LOCUS       DATWEK010000001       138743 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.001, whole genome shotgun sequence.
ACCESSION   DATWEK010000001 DATWEK010000000
VERSION     DATWEK010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 138743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 138743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..138743
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.001"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..366
                     /locus_tag="VCR92_000001"
     CDS             <1..366
                     /locus_tag="VCR92_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4267104.1"
                     /translation="ALAFHLFTGQAYYGIVIDRMIKQLPFYIAIIALCQFLFNILRKT
                     YQSITAYILYVLLFDKVSATLANHFFKLDISPVLMFKHLSLSLGDKHLSSTSILVAFG
                     LTLCYLLGNVFLFSKRELK"
     gene            complement(715..1680)
                     /locus_tag="VCR92_000002"
     CDS             complement(715..1680)
                     /locus_tag="VCR92_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEP4267105.1"
                     /translation="MKKILVLHTGGTISMQADNSGRVVPNQDNPMTKIHAAAQDIQLT
                     VSDFLNLPSPHITPHHMLSIYHHIQERTDVFDGIVITHGTDTLEETAYFLDTMALPTN
                     IPVVLTGAMRSSNEVGSDGIYNYLTALRVASSDKAKEKGVLVVMNDEIHAAKYVTKTH
                     TTNISTFQTPTHGPLGIIMKNDLLFFKTAEPRIRFDLRCISGTIPIIKAYAGMGDGSI
                     LSLLTPGSIQGLVIEALGAGNVPPLAVGEIEHLITLGIPVVLVSRCFNGMAEPVYAYE
                     GGGAMLQEAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            1752..3140
                     /locus_tag="VCR92_000003"
     CDS             1752..3140
                     /locus_tag="VCR92_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEP4267106.1"
                     /translation="MTVKAVFFDIDGTLLNDRKNIQKTTQKAIQQLKKQGIMVGLATG
                     RGPGFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSMIYKVIRYANEKKREIS
                     LGTASGLAGSRIIDMGTSPFGQVISSFVPKSWARTVEGSFKHLIRRIKPQSFRNLVTI
                     MREPIYQVVLVASQAETKKIQEKFPHIKITRSSPYSLDLISVDQSKIKGIERLGEMFG
                     FDLSEVMAFGDSDNDLEMLSGVGIGIAMGNAETVVKDGAHFTTDSNNNDGISKALAHY
                     GLIHFDIEKSFKSRDENFNKVKDFHRLMDSDTIETPRSYTISEAGYRSGFKVEEIVEF
                     LYAASKGDQQQFTQAIFDLHGAVDQAANKVQAKKHVETPLIGQVDALADLLYFTYGSF
                     VLMGVDPQPIFEAVHEANMAKIFPDGKAHFDPVTHKIQKPDYWQERHAPEVAIKKELD
                     KQLQKSLQRFDK"
     gene            complement(3263..3715)
                     /locus_tag="VCR92_000004"
     CDS             complement(3263..3715)
                     /locus_tag="VCR92_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEP4267107.1"
                     /translation="MSLKYKRILVAIDGSYESELAFNKGVNVALRNDATLLLVHVIDT
                     RALQSVATFDTYIYEKLEQEAKDVLDDFEKQAQIAGITNIKQIIEFGNPKNLLAHDIP
                     DRENADLIMVGATGLNTFERLLIGSSSEYIMRHAKIDLLVVRDSTKTL"
     gene            3946..5160
                     /locus_tag="VCR92_000005"
     CDS             3946..5160
                     /locus_tag="VCR92_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEP4267108.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPA
                     AFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIEDIYLGN
                     GVSELISISLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
                     IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGK
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAIPGLSAVKPEAGLYL
                     FPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQ
                     EKITRVLYQYRR"
     gene            5378..6160
                     /gene="codY"
                     /locus_tag="VCR92_000006"
     CDS             5378..6160
                     /gene="codY"
                     /locus_tag="VCR92_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEP4267109.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYVKAASRVYDTEANLSVENELTIF
                     PVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
                     LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASIIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFAKLKEF"
     gene            6307..6861
                     /locus_tag="VCR92_000007"
     CDS             6307..6861
                     /locus_tag="VCR92_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEP4267110.1"
                     /translation="MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQG
                     DYIFFAIDCHDQNDPWHPESKLFAAHNIKGTTGRHLYGPLAEVYSYMKQHPRVFWIDK
                     RYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGYQLEIVKSAVASL
                     TKESYEWSLAHFEQVLGAKLINDY"
     gene            7305..7623
                     /locus_tag="VCR92_000008"
                     /pseudo
     CDS             7305..7623
                     /locus_tag="VCR92_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991537.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dikinase"
     gene            7855..8157
                     /gene="gatC"
                     /locus_tag="VCR92_000009"
     CDS             7855..8157
                     /gene="gatC"
                     /locus_tag="VCR92_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEP4267111.1"
                     /translation="MKISEEEVRHVAKLSKLSFLESETTTFATTLSKIVDMVELLNEV
                     DTEGVAITTTMADKKNVMRQDIAEEGTDRALLFKNVPEKENHFIKVPAILDDGGDA"
     gene            8157..9623
                     /gene="gatA"
                     /locus_tag="VCR92_000010"
     CDS             8157..9623
                     /gene="gatA"
                     /locus_tag="VCR92_000010"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEP4267112.1"
                     /translation="MSFNHKTIEELHDLLVAKEISATELTQKTLEDIKSREEAVGSFI
                     TVSEEAALKQAAAIDAKGIDADNLMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATSVANAYAKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHTKVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGTVSRYGLIAFGSSLDQIGPFAPTV
                     KENAQLLNVIASSDVKDATSAPVRIADYTSKIGRDIKGMKIALPKEYLGEGIDPEIKE
                     TVLAAAKQFEALGATVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRADDA
                     KNLDEIYVNTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIEDFDKVFA
                     DYDLILGPTTPTVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFVDGLPVG
                     LQLIGPKYAEETIYQAAAAFEAVTDYHKQQPIIFGGDK"
     gene            9623..11062
                     /gene="gatB"
                     /locus_tag="VCR92_000011"
     CDS             9623..11062
                     /gene="gatB"
                     /locus_tag="VCR92_000011"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEP4267113.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNANTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMDIHKEMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEIKLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEQFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKLLRSGGVIRQETRRYDEANKGTILMRVKEGAADYRYFPEPD
                     LPLYEIDDAWIDEMRAQLPQFPAQRRAKYEEELGLSAYDASQLTATKALSDFFETAVS
                     LGGDAKQVSNWLQGEVAQFLNAEGKTIEEIRLTPDNLVEMIAIIADGTISSKMAKKVF
                     VHLAKNGGSARAYVEKAGLVQISDPAVLVPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVAQQLLAQELQKLRD"
     gene            11059..11274
                     /locus_tag="VCR92_000012"
     CDS             11059..11274
                     /locus_tag="VCR92_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267114.1"
                     /translation="MIVADSNKLKYFVSEKKAVGLSQAAFLYVMLVTVYKKTIIYAKI
                     RLTGIALEPSGVSDVYLMNYHVCLHYY"
     gene            11493..11732
                     /locus_tag="VCR92_000013"
     CDS             11493..11732
                     /locus_tag="VCR92_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEP4267115.1"
                     /translation="MIWSLIVGAFIGMIAGKMTEKSQSMGCFTNIIAGLIGSAVGQRL
                     FGDWGIQLAGMAIFPSILGAAIVIVLVSAIFGKRY"
     gene            12124..12831
                     /locus_tag="VCR92_000014"
     CDS             12124..12831
                     /locus_tag="VCR92_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEP4267116.1"
                     /translation="MTKTRLYIARHGKTMFNTIGRAQGWSDTPLTKKGEEGIRELGLG
                     LKDATIPFKAAFSSDSGRTMQTIEIILRESENEFLPYTKDNRIREWCFGSLEGTYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLRKRIWEGFEAIAL
                     SIQNAGGGNALVVSHGMTIGTFMWLIDPDREKQYIDNGSVTVVEFEDGQFTIKTIGDM
                     SYRYRGREIIEAMSDEA"
     gene            12821..13564
                     /locus_tag="VCR92_000015"
     CDS             12821..13564
                     /locus_tag="VCR92_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEP4267117.1"
                     /translation="MKHNHFKLLLQTLVVLLFVGGIYLFIKPEKQATKTPSSQQASSQ
                     KVVKNSKESTGLPKVSPKDWELILVNRDHMTEELSPELVDINGISVDKRIEQATSDFL
                     AAAQAIDPQEHLISGYRSVAYQAELYQSYIKKEMANDPTLTQEAAEALVQTYLQPPGA
                     SEHHTGLAIDMSTVDTLNASDPSVSKAVQKIAPDYGFVLRFPEGKKTSTGVDYEDWHY
                     RYVGKASARYMAQHNLTLEEYIAALKEKR"
     gene            13561..14130
                     /locus_tag="VCR92_000016"
     CDS             13561..14130
                     /locus_tag="VCR92_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEP4267118.1"
                     /translation="MRKRLKFPYFLTLLACFLLLIVCPLLSSQRIASADKEVRVNYSQ
                     KQFITKMGKEVKPLAKYYGIRPSILIAQILLETHDGKTLLASKYHNLFSKKATPGQAA
                     ITLKSPKQTNQNVRYAIYKDDASAIRDYLRMLRQGKEVDKRLYRNLATEKGYKAPAKS
                     LQKYLHYTDKTYARRLIQVIESNDLTNYD"
     gene            14265..15299
                     /gene="hrcA"
                     /locus_tag="VCR92_000017"
     CDS             14265..15299
                     /gene="hrcA"
                     /locus_tag="VCR92_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001872861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEP4267119.1"
                     /translation="MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKTFDFEAFKLE
                     DMLQKASHILAEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQ
                     FAIPRNFLTRDLIAFKAIVEERLLDSSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFD
                     YVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADS
                     QEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYR
                     YLNSNHYEVH"
     gene            15302..15874
                     /gene="grpE"
                     /locus_tag="VCR92_000018"
     CDS             15302..15874
                     /gene="grpE"
                     /locus_tag="VCR92_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEP4267120.1"
                     /translation="MAVFNKLFKRRHSVSEEIKKDDLQEEVEATETEETVEEVIEETP
                     EKSELELANERADEFENKYLRAHAEMQNIQRRSSEERQQLQRYRSQDLAKAILPSLDN
                     LERALAVEGLTDDVKKGLEMTRDSLIQALKEEGVEEVEVDSFDHNFHMAVQTLPADDE
                     HPADSIAEVFQKGYKLHERLLRPAMVVVYN"
     gene            16055..17881
                     /gene="dnaK"
                     /locus_tag="VCR92_000019"
     CDS             16055..17881
                     /gene="dnaK"
                     /locus_tag="VCR92_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEP4267121.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPETVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDK
                     DEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFD
                     DLTRDLVERTKTPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIDRMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQSALDELKAAQESGNLDDMKAKLEALNEKAQ
                     ALAVKMYEQAVAAQQAAQGAEGAQANDSANNDDVVDGEFTEK"
     gene            18162..19298
                     /gene="dnaJ"
                     /locus_tag="VCR92_000020"
     CDS             18162..19298
                     /gene="dnaJ"
                     /locus_tag="VCR92_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEP4267122.1"
                     /translation="MNNTEYYDRLGVSKDASQDDIKKAYRKMSKKYHPDINKEAGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGAQGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGSRNPNAPRQGDDLQYRVNLSFEEAVFGVEKEVSYNREATCGTCLGSGAKPGTA
                     PVTCRKCHGSGVMTIDTQTPLGMMRRQVTCDICHGSGKEIKEPCQTCHGTGHEKQAHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYNLDI
                     SFTQAALGDTVEIPTVHGDVEMAIPAGTQTGKTFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNDAQREALQAFAEASGEKMLHPKKKGFFDKVKDALEDI"
     gene            19518..20309
                     /locus_tag="VCR92_000021"
     CDS             19518..20309
                     /locus_tag="VCR92_000021"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEP4267123.1"
                     /translation="MQFKHIIFDVVDDLATLTLNRPEVSNGFNIPICQEILVALAEVK
                     RDTSVRFLLIKAVGKVFSVGGDLVEMQEAVAKDNVQSLVKIAELVQEISFAIKHLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGITADKGLDYGFVYRTAESDKLDKVCLQLLKRLRRGSSNSYAGMKSLVW
                     QSFFTGWEDYAKAELAIQEELAFKEDFKEGVIAFGERRRPNFQGK"
     gene            20386..20820
                     /locus_tag="VCR92_000022"
     CDS             20386..20820
                     /locus_tag="VCR92_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEP4267124.1"
                     /translation="MEYDKINQYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYDQVTPSDIARELMVTLGTVTTSLNKLEAKGYIARTRSRSDRRVVYLSLTKRGRLL
                     DRLHAKFHKNMVGHVIADMSDEEMQALVRGLGNLHQFLEDLV"
     gene            20821..21795
                     /locus_tag="VCR92_000023"
     CDS             20821..21795
                     /locus_tag="VCR92_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEP4267125.1"
                     /translation="MIFSKISQVAHYVPQQLVTNNDLASIMDTSHEWIFSRTGIAERH
                     ISRDEMTSDLAIQVADQLLTQSGLKADAIDFIIVATISPDATMPSTAAKVQAAIAATS
                     AFAFDMTAACSGFVFALAMADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDG
                     AGGVLLEASKDKHVLAETLHTDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIF
                     DFAIRDVSKSILTLMAQSDITKDDIDYCLLHQANRRILDKIARKIDVPREKFLENMMR
                     YGNTSAASIPILLSEAVQKGQIRLDGTQKILLSGFGGGLTWGSLIVKI"
     gene            21856..22080
                     /locus_tag="VCR92_000024"
     CDS             21856..22080
                     /locus_tag="VCR92_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEP4267126.1"
                     /translation="MAVFEKVQEIIVEELGKETEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKSK"
     gene            22282..23253
                     /gene="fabK"
                     /locus_tag="VCR92_000025"
     CDS             22282..23253
                     /gene="fabK"
                     /locus_tag="VCR92_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEP4267127.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDRPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHQAGIIVVPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMSLVRQVVEA
                     VSIPVIAAGGIADGHGAAAAFMLGAEAVQIGTRFVVAKESNAHQNFKDKILAAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKAFLIGQKTATDIEEMGAGSLRHAVIEGDVVN
                     GSVMAGQIAGLVRKEESCETILKDIYYGAARVIQNEAKRWQSVSIEK"
     gene            23278..24216
                     /gene="fabD"
                     /locus_tag="VCR92_000026"
     CDS             23278..24216
                     /gene="fabD"
                     /locus_tag="VCR92_000026"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEP4267128.1"
                     /translation="MTKTAFLFAGQGAQKLGMARDFYDNFAIVRKTFDQASQVLGYDL
                     RRLIDSDELKLNQTSYTQPAILTSSIAIYRVLGLHHVKPDMVAGLSLGEYSALVASGA
                     LSFEDTLSLVAKRGRLMEEAAPQGSGKMVAVMNTDVQVIEEVCQIAAKHGVVAPANYN
                     TPSQIVIGGQTDAVNVAVELLKERGVKRLIPLNVSGPFHTALLEPASRLLAKELERYN
                     FSDFKIPLVGNTEANIMEKDRIPELLARQVMEPVRFYDSVATLVESGITQFIEVGPGK
                     VLTGFVKKIDKNLLCTSVENMVSLRLFLDREDIHGN"
     gene            24206..24940
                     /gene="fabG"
                     /locus_tag="VCR92_000027"
     CDS             24206..24940
                     /gene="fabG"
                     /locus_tag="VCR92_000027"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEP4267129.1"
                     /translation="MEIKGKNIFITGSTRGIGLAMAHQFASLGANIVLNGRSAISEEL
                     VASFTDYGVTVVTISGDVSEASEAKRMVNEAIESLGSIDVLVNNAGITNDKLMLKMTE
                     EDFERVLKINLTGAFNMTQSVLKPMIKARQGAIINVSSVVGLTGNIGQANYAASKAGM
                     IGFTKSVAREVAARNICVNAIAPGFIESDMTGVLPEKMQEQILSQIPMKRIGKAQEVA
                     HLASFLVEQDYITGQVIAIDGGMTMQ"
     gene            24955..26187
                     /gene="fabF"
                     /locus_tag="VCR92_000028"
     CDS             24955..26187
                     /gene="fabF"
                     /locus_tag="VCR92_000028"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEP4267130.1"
                     /translation="MTFKRVVVTGYGLTSPIGHDPETFWNNLKAGQIGIGPITKFDTT
                     DYAVKNAAEIQDFPFDKYFVKKDLNRFDRYSLYALYAAKEAINHADLNIEMVDSDRFG
                     VIVASGIGGIAEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMSLKAQGVCKSI
                     NTACASSNDAIGDAFRAIKFGTQDVMIVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQERGATILAEIVGYGNTCDAYHMTSPNPEG
                     LGARKAIHLALQEAGIEASAINYVNAHGTSTPANEKGESQAIVAVLGKDVPVSSTKSF
                     TGHLLGAAGAIEAIATIEAMRHNYVPMTAGTQALSEDIEANVIFGEGKETAINYAISN
                     TFGFGGHNAVLAFKCWEE"
     gene            26189..26689
                     /locus_tag="VCR92_000029"
     CDS             26189..26689
                     /locus_tag="VCR92_000029"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEP4267131.1"
                     /translation="MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASTS
                     NQEHAVPVPQVQLVPNSTASEASSPASVKDVPVEEQPQAESFVAEGDIVESPLVGVAY
                     LAASPDKPPFVAVGDTVKKGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQ
                     GLVRIK"
     gene            26686..27108
                     /gene="fabZ"
                     /locus_tag="VCR92_000030"
     CDS             26686..27108
                     /gene="fabZ"
                     /locus_tag="VCR92_000030"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEP4267132.1"
                     /translation="MMDIREIQAALPHRYPMLLVDRVLEVSDDHIVAIKNVTINEPFF
                     NGHFPHYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFIKRRGTIAVVEARAEVDGKLAASGTLTFACGQ"
     gene            27140..28504
                     /locus_tag="VCR92_000031"
     CDS             27140..28504
                     /locus_tag="VCR92_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEP4267133.1"
                     /translation="MFKKILIANRGEIAVRIIRAARELGISTVAVYSEADKEALHTIL
                     ADEAICIGPARSKESYLNMNSVLSAAIVTGAQAIHPGFGFLSENSKFATMCEEMNIKF
                     IGPSASVMDKMGDKINARSEMIKAGVPVIPGSDGEVYNAQEALAIANKIGYPVMLKAS
                     AGGGGKGIRKVETEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDAH
                     GNIIHLGERDCSLQRNNQKVLEESPSIAIGNTLRHEMGQAAVRAAEAVAYENAGTIEF
                     LLDEDSEKFYFMEMNTRIQVEHPVTEFVTGVDIVKEQIKIAAGQPLAISQEDITITGH
                     AIECRINAENTAFNFAPSPGKITDLYMPSGGVGLRVDSAVYNGYAIPPYYDSMIAKII
                     VHGSNRFDALMKMQRALVELEIEGIITNTDFQLDLISDKRVIAGDYDTSFLMETFLPH
                     YNKD"
     gene            28513..29379
                     /locus_tag="VCR92_000032"
     CDS             28513..29379
                     /locus_tag="VCR92_000032"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEP4267134.1"
                     /translation="MALFRKKDKYIRITPNNSLKGSVSHNVPEVPDELFAKCPACKHM
                     IYKKDLGLAKICPTCSYNFRISAQERLTLTVDEGSFQELFTSIETKDPLRFPGYQEKL
                     QKAKETTGLHEAVLTGKAMVKGQQIALAIMDSHFIMASMGTVVGEKITRLFELAIEEN
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAVKRHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDIILAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLQDHGFVDAIVKRTELRDK
                     IAHLVAFHGGGQ"
     gene            29376..30146
                     /locus_tag="VCR92_000033"
     CDS             29376..30146
                     /locus_tag="VCR92_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEP4267135.1"
                     /translation="MTDVSRILKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGA
                     IVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRLMKQAEKFGRPVV
                     TFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPEHGYF
                     SSEIVDIIKANLIEQITSLQAKPLDQLLDERYQRFRKY"
     gene            complement(30379..31656)
                     /gene="serS"
                     /locus_tag="VCR92_000034"
     CDS             complement(30379..31656)
                     /gene="serS"
                     /locus_tag="VCR92_000034"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEP4267136.1"
                     /translation="MLDLKRIRTDFDTVAAKLKNRGVSEDTLTHLKELDEKRRALLVQ
                     SEELKAERNIASAAIAQAKRQKEDATQQIADMQKVSADIKTIDNQLVAIDQQVTDIIT
                     VLPNTPHDSVPVGADEEDNVEIRRWGTPRDFDFEVKAHWDLGEDLDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTF
                     ELADTNFVLIPTAEVPLTNYYRGEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLGLPYRVISLCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRSYMGGETVISPK"
     gene            complement(32048..32407)
                     /locus_tag="VCR92_000035"
     CDS             complement(32048..32407)
                     /locus_tag="VCR92_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEP4267137.1"
                     /translation="MAQSLNTSVEYKTKAVSYLGIGGKVGHILLGDKALEFYNDKNVN
                     DYIQIPWTAINHIGANVSRKKVSRHFEIFTDQGKFLFASGDSGKILKITRQHIGNEKV
                     ITLPTLMQTFINKFFRH"
     gene            complement(32521..33432)
                     /locus_tag="VCR92_000036"
     CDS             complement(32521..33432)
                     /locus_tag="VCR92_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000139230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEP4267138.1"
                     /translation="MTEQIKLTKSDRQRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTSPEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTPIDDKAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLASTGNIVGPLLFFFGWNLIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTIDLPGKQLSDGA
                     YVVFPDGAVKGAELKTILANAIGGMSLDKVQAQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIGLFAFGILAHLAGIM"
     gene            complement(33449..34258)
                     /locus_tag="VCR92_000037"
     CDS             complement(33449..34258)
                     /locus_tag="VCR92_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEP4267139.1"
                     /translation="MSDISIISAILVVIIAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVILGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKSGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTLSTALVHAGDKAATEGNFAGIERFHFIALLLQGLRIAVPA
                     ALLVAVPTSAVQSVLNAMPNWLNEGMQIGGAMVVAVGYAMVINMMATREVWPFFALGF
                     ALAAISQLTLIAMGVIGVAIAFIYLNLSKKGGNGGNAAGSADPIGDILEDY"
     gene            complement(34347..35339)
                     /gene="manX"
                     /locus_tag="VCR92_000038"
     CDS             complement(34347..35339)
                     /gene="manX"
                     /locus_tag="VCR92_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEP4267140.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIQQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDAGAGVEQVAANIIKESKDGIKALPEDLNPVEETAATEKVVNALQGAIPAG
                     TVIGDGKLKINLARVDTRLLHGQVATAWTPASKADRIIVASDEVAQDDLRKQLIKQAA
                     PGGVKANVVPISKLIEASKDPRFGNTHALILFQTPQDALRAVEGGVEINELNVGSMAH
                     STGKTMVNNVLSMDKEDVATFEKLRDLGVTFDVRKVPNDSKKNLFELIQKANIK"
     gene            complement(35691..36503)
                     /locus_tag="VCR92_000039"
     CDS             complement(35691..36503)
                     /locus_tag="VCR92_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEP4267141.1"
                     /translation="MTKKLIAIDLDGTLLHHDNTISTYTQKIIKAVQDKGHHVIISTG
                     RPYRMALDYYLQLNLKTPIITFNGALTHMPEQKWAYEHNVTLDKGYLLRLLKYQDDFQ
                     MDFIASEYRKNVYITMTNPESIDPQLFGVDEITQDMALEITKITRNPNALLMQTHHED
                     KYALAKNMRAFFKDEIEIDSWGGPLNILEISSKNVNKAYALNYLLGIYNMDKKDLIAF
                     GDEHNDTEMLAFAGTGYAMKNASPVLLPYADQQLNFSNEEDGVAKKLEELFL"
     gene            36767..38227
                     /locus_tag="VCR92_000040"
     CDS             36767..38227
                     /locus_tag="VCR92_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEP4267142.1"
                     /translation="MEKFFKLSENGTTVSTEIMAGLTTFFAMSYILFVNPSILGAAGM
                     PSNAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFALGFSWQEALAM
                     VFICGLFNIFITVTKFRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANIITFSISAE
                     NIVMVNGVEPAKASAKTFADGLLFVDANGGVVPTISSFTDSSVLLAIFGLLLTTALVI
                     RNFRGAILIGIVATTLVGIPLGIVDVSNLNFGISHIGEAWTELGTTFLAAFDGLSSLF
                     SDSSRLPLVFMTIFAFSLSDTFDTIGTFIGTGRRTGIFSQDDENALENSIGFSSKMDR
                     ALFADAIGTSIGALVGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFLLSILLLPLVG
                     IVPAAATAPALIVVGVMMVSSFLDVNWSKFADALPAFFAAFFMALCYSISYGIAAAFI
                     FYCLVKVVEGKTKDIHPIIWGATFLFIVNFIILTIL"
     gene            38381..38842
                     /gene="tsaE"
                     /locus_tag="VCR92_000041"
     CDS             38381..38842
                     /gene="tsaE"
                     /locus_tag="VCR92_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEP4267143.1"
                     /translation="MFYSENEYTLKAYGETLGTYLSIGDVIVLSGDLGAGKTTLAKGI
                     AKGMGISQMIKSPTYTIVREYEGRLPLYHLDIYRVGDDPDSIDLDDFLFGNGVTVIEW
                     GELLGEGLLQDYLQITITKRDKGRQLDLLAHGERSRQLLEIMSHDSAKSRY"
     gene            38817..39341
                     /locus_tag="VCR92_000042"
     CDS             38817..39341
                     /locus_tag="VCR92_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP4267144.1"
                     /translation="MIQQSLVIEEGVPQDAKAVLSLVAAAAKETDFITGVETILEATP
                     HELSDFLSRSQTSFIDFCLLARLDEKVVGLLNLSGEVLSQGQVEADVFMLVAKTYRGY
                     GIGQLLLEIALDWAEENPYIESLKLDVQVRNTKAIYLYKKYGFRIESMRKNDIKSKNG
                     DDLDVYHMRKSVSQ"
     gene            39350..40633
                     /locus_tag="VCR92_000043"
     CDS             39350..40633
                     /locus_tag="VCR92_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEP4267145.1"
                     /translation="MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTGELSKTFKDF
                     STSSKKSDAIKQTRAFSILLMGVDTGSSERASKWEGNSDSMILVTVNPKTKKTTMTSL
                     ERDTLTTLSGPKNNEMNGVEAKLNAAYAAGGAQMAIMTVQDLLNITIDNYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIAENEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALDSISSYRKILSAVSSNMQTNIEISSRTIPSLLGYRD
                     ALRTIKTYQLKGEDATLSDGGSYQIVTSNHLLEIQNRIRTELGLHKVSQLKTNATVYE
                     NLYGSTKSQTVNNNYDSSGQAPSYSDSHSSYANYSSGVDTGSSYQSASTDQDSTASSH
                     TPTTPSSSSDALAADESSSSGSGSLVPPANINPQT"
     gene            complement(40744..41100)
                     /locus_tag="VCR92_000044"
     CDS             complement(40744..41100)
                     /locus_tag="VCR92_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEP4267146.1"
                     /translation="MKVKTVIAVGLLSFTAYKAYQKRCTIKELLSISRQAKDAAQLDL
                     DNIKANLDLIHSQGKVIQNISQDLAHKWRYFNQETQAHLTEIQNRMAKYQEDSELISS
                     ESPTCQTVILTNNHSR"
     gene            complement(41097..41516)
                     /locus_tag="VCR92_000045"
     CDS             complement(41097..41516)
                     /locus_tag="VCR92_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEP4267147.1"
                     /translation="MENCIFCSIIQGDIPSSKVYEDEQVLAFLDISQTTKGHTLVIPK
                     QHVRNLLEMTAETASHLFARIPKIARAIQLATGATAMNIINNNEALAGQTVFHAHVHL
                     VPRYNEKDGISIQYTTHEPNFPVLEKLARQINQEVSS"
     gene            41588..42313
                     /locus_tag="VCR92_000046"
     CDS             41588..42313
                     /locus_tag="VCR92_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4267148.1"
                     /translation="MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIPETPSLYEELTLSEHINTVAMAY
                     DIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLAD
                     LQEAFGDRSASLNDIYLALTKED"
     gene            42316..43350
                     /locus_tag="VCR92_000047"
     CDS             42316..43350
                     /locus_tag="VCR92_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4267149.1"
                     /translation="MKALFLKRRQDFQKQQNKYLRYVLNDHFVLVLMFLLGYAMVQYG
                     QLLNHFPTNHLPIQVCLGILIPLLLSMGSIATYLEEADQHFLLPKEEEVISYIKQAER
                     LSFLLWGTLQTAILLFLYPIFRRLGLSLFIFIILVLILLALKRVVLSRKTRYFLRGNR
                     LDWAKAVAFESNRKQSILKFYSLFTTVKGISTKVKERTYLNPLLKLVKQTPSNLWLSL
                     YARAFLRSSDYLGLFLRLMLLSSLSVFFIHNLYLSVSLALIFNYLVVFQLLSLYYHYD
                     YHYMTSLYPENSRSKKKNVLSFLRGLSFLMLIVNMLCCSSAPKALILIVGMVFIACIY
                     LPYKLKKIID"
     gene            43414..44205
                     /locus_tag="VCR92_000048"
     CDS             43414..44205
                     /locus_tag="VCR92_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEP4267150.1"
                     /translation="MTTTEQELTLTPLRGKSGKAYKGTYPNGECVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTKEDMNSKQIIHILLRLHKSKKLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFKSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDSVRLTDRMYDVAYLLSHYIPRSRWSEWLSYYGYKNNDKV
                     MQKIIWYGQFSHLTQILKCFDKRDMEHVNQEIYALRKFREIFRKK"
     gene            44205..44840
                     /gene="trmB"
                     /locus_tag="VCR92_000049"
     CDS             44205..44840
                     /gene="trmB"
                     /locus_tag="VCR92_000049"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEP4267151.1"
                     /translation="MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIE
                     VGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSLTN
                     YFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFE
                     YSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNKGQVIYRVEANF"
     gene            44905..44991
                     /locus_tag="VCR92_000050"
     tRNA            44905..44991
                     /locus_tag="VCR92_000050"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:44939..44941,aa:Ser,seq:gga)
     gene            45099..45635
                     /gene="rimP"
                     /locus_tag="VCR92_000051"
     CDS             45099..45635
                     /gene="rimP"
                     /locus_tag="VCR92_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEP4267152.1"
                     /translation="MDSQGPIILEKSIKIEEVIKIANTSIIDIVTKTVTPEIKAPYEL
                     VDVEYDKMGSDYILSILVDKEGGITVEDTSDLTNIISPLLDTIDPDPFPNQYMLEVSS
                     PGLERPLKTADSLKAAVGSYINVSLYQAIDKVKVFQGDLLAFDGETLTIDYLDKTRHK
                     IVNIPYQAVAKVRMAVKL"
     gene            45810..46967
                     /gene="nusA"
                     /locus_tag="VCR92_000052"
     CDS             45810..46967
                     /gene="nusA"
                     /locus_tag="VCR92_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEP4267153.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIDAVTESLKSAYKRRYGQSES
                     CVIEFNEKTADFQVFTVREVVEEVFDSRLEISLKDALAISSAYELGDKIRFEESVNEF
                     GRVAAQSAKQTIMEKMRRQMREVMFNEYKEHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRVDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDEDLKRATVVVPDSKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYDRLEAEKEAATVVEEPVVDDVMTAEEV"
     gene            46983..47279
                     /locus_tag="VCR92_000053"
     CDS             46983..47279
                     /locus_tag="VCR92_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEP4267154.1"
                     /translation="MSKVKKIPLRKSLVSGEIIAKRDLLRIVKTKDGQVFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMDIPESFYDDLIAYVDHKIKRRELGLD"
     gene            47272..47574
                     /locus_tag="VCR92_000054"
     CDS             47272..47574
                     /locus_tag="VCR92_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEP4267155.1"
                     /translation="MTNLERLSSLIGLAQRAGKVISGEELVVKAIQHQQVILVFLAND
                     AGPNVTKKVTDKSNYYNVEVSTVLNALELSAALGKPRKVAAVADAGFSKKMRTLME"
     gene            47594..50455
                     /gene="infB"
                     /locus_tag="VCR92_000055"
     CDS             47594..50455
                     /gene="infB"
                     /locus_tag="VCR92_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEP4267156.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVEHAKYLGLDVKSHASSVEEADAK
                     KIISSFSKASKPDVTASQTVKPKEVAQPSVTVVKETGSEHVEKTQVSKPKSRNFKAER
                     EARAKEQAARKQANGSSHRSQERRGGYRQPNNHQTNEQGDKRITHRSQGDTNDKRIER
                     KASNVSPRHDNHQLVGDRNRSFAKENHKNGRFTNQKKQGRQEPQSKSPKIDFKARAAA
                     LKAEQNAEYSRQSETRFRAQQEAKRLAELARQEAKEAALKAQAEEMSHREAALKSIEE
                     AETKLKSSNISAKSTADNRRKKQARPEKNRELTHHSQEGQKKNKKSWNSQNQVRNQKN
                     SNWNKNKKTKKGKNVKNTNTAPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAE
                     IVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDDADIERFFEDENYLNPE
                     NIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFL
                     DTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAINKID
                     KPGANPERVIAELAEYGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEELKA
                     DPTVRAIGTVIEARLDKGKGAIATLLVQQGTLHVQDPIVVGNTFGRVRAMVNDLGRRV
                     KSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERSKRALLKQRQNTQRVSLD
                     NLFDTLKAGEIKTVNVIIKADVQGSVEALAASLVKIEVEGVRVNVVHSAVGAINESDV
                     TLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDPVYQ
                     EKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSSVRVIRDSVVIFDGKLASLKHYK
                     DDVKEVGNAQEGGLMIENFNDLKVDDTIEAYIMEEIVRK"
     gene            50661..51011
                     /gene="rbfA"
                     /locus_tag="VCR92_000056"
     CDS             50661..51011
                     /gene="rbfA"
                     /locus_tag="VCR92_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEP4267157.1"
                     /translation="MANHRIDRVGMEIKREVNDILQKKVRDPRVQGVTITEVQMQGDL
                     SLAKVYYTIMSDLASDNQKAQTGLEKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELDKKD"
     gene            complement(51064..52065)
                     /locus_tag="VCR92_000057"
     CDS             complement(51064..52065)
                     /locus_tag="VCR92_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEP4267158.1"
                     /translation="MKKTLKSTLILLGLTLAIGASTQVDASSRSWKSWFIEKYFWLKG
                     DKGYYSEQDETKFDQYVNSAGEASNKGFDLKEEQVNGTLVTKTVDNMQVHTWNENPSN
                     KANQKVIFYLHGGSYLNNPTTYHIDMLKTLSTSLDAKIILPIYPKAPTYSYSDAMPKL
                     VDLYRDTLKETTAQNITIMGDSAGGGLALGLALALKNESLKQPKDIVLLSPWLDVTMS
                     NPDIESYESNDPILSAWGLRKVGEIWARRDPNNTKHPYVSPINGDVSGLAPITMFVGT
                     HEIFYPDVKKFDDILTAKGHQHELIVADKMNHVYPIYPIEEAKTAQYQIIDTIQKAY"
     gene            52228..52665
                     /locus_tag="VCR92_000058"
     CDS             52228..52665
                     /locus_tag="VCR92_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEP4267159.1"
                     /translation="MNQNISAAEWEVMRVVWASGDIKSSDIITILRKKYQWSDSTIKT
                     LIGRLVEKKALGTYRQGRAYIYQALLDETLLQKEALATVLDGICQRQHTHLLLERLYD
                     LPMTLEEIEAFQELLEVKKENAVLEVSCNCLPGQCHCQKKETY"
     gene            52665..54896
                     /locus_tag="VCR92_000059"
     CDS             52665..54896
                     /locus_tag="VCR92_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEP4267160.1"
                     /translation="MAKEIFLVEGMSCASCALTIEKMVNQLPEVEQAVVNLATEKLTV
                     TYQDDDLETAKVIQAVKAAGYGAQVFDEHAKHMQTGRRDEDLKVIWSQVLWSALFTIP
                     ILYLAMGHMVGLWLPPFLQPDRYPFVYSFSQLLLTIPVLVLNRHYYHNGFKALFKGYP
                     NMDSLVALATSFAFAYSLYGVVEISLGQANFVHSLYFESVVVILTLIGLGKYFESRSK
                     GRTSQAIQKLLSLKATVVRVWRNSQWQLLPLEEVSYDDLVLVQPGEKVSIDGIIVEGH
                     SSLDESFLTGESLPVEKGEKDNVFAGSLNGPGALTIKPDKLGNDTLLAQIIQLVENAQ
                     ENKAPIAAIADKVSGVFVPVVLVLALLTGVFWLVFMQESLRFSLTTAIAVLVIACPCA
                     LGLATPTAIMVGTGRAAENGILFKGGDILEQAHQVDTVVFDKTGTITEGKPSLQKLLT
                     FSGDDHLILQEAASLEAYSQHPLGEAIVRAAQEAGYDSLPVEEFESLTGLGVTGQLEG
                     RRLAIGNAALMGILGIDLSCVQSVCAKASEKGQTLVYYAKEGQLRALFSIADAVKEDS
                     QATVEALHQLGIHTIMLTGDHDATAKAIASQVGITDVISQVLPDQKAGVIADLRSQGR
                     KVAMVGDGINDAPALAVADIGIAMGSGTDIAIESADVILMKPDMLDLVKAMSLSRATM
                     RIVKENLFWAFIYNVLMIPVAMGLLHLFGGPLLNPMLAGFAMSFSSVSVVLNALRLKG
                     KTI"
     gene            54910..55113
                     /locus_tag="VCR92_000060"
     CDS             54910..55113
                     /locus_tag="VCR92_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HEP4267161.1"
                     /translation="MEKHYQVTGMTCDGCARTVTEKLSAVPGVQSVQVNLEKGQAKVT
                     GRPLTFLLKRALKDTKFELHQSS"
     gene            complement(55317..56087)
                     /locus_tag="VCR92_000061"
     CDS             complement(55317..56087)
                     /locus_tag="VCR92_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEP4267162.1"
                     /translation="MLKRERLLKITEIVNEQGIVTVNDIIQTLNVSDMTVRRDLDELE
                     KAGKLIRIHGGAQSITMPNKKERSNIEKQTVQTKEKWELASYATQLVNDGETIFIGPG
                     TTLECFAEQLKNRQIRIVTNSLPVFNILQDSETIDLILIGGEYRSITGAFVGSLASQN
                     ISSLKFAKAFISCNGIYKNDIATYSETEGEIQKLAFNNSIEKYLLVDNQKFNAYDFFI
                     FYHLNNIDAVVTDSQITEDVIERYSQFTQLLVAHENKE"
     gene            56324..56797
                     /locus_tag="VCR92_000062"
     CDS             56324..56797
                     /locus_tag="VCR92_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEP4267163.1"
                     /translation="MFPNILFTEARTQPELFDLVASYLEKVGYVTQEYHQALVEREAV
                     FPTGLKVDLKDGSDILYAAIPHTETKYCLVDQVVYVRNSQALTFKHMINPEEDCLVTD
                     FFFIINSQNEGQTTILSNLITFFITKGNLSYLASLKDDKQAISNYLIEKGVFQHD"
     gene            56790..57095
                     /locus_tag="VCR92_000063"
     CDS             56790..57095
                     /locus_tag="VCR92_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEP4267164.1"
                     /translation="MIKILAACGAGVNSSHQIKDAIETQMSDRGYDVHCDAVMVKDIT
                     EELVSRYDIFTPIAKTDLGFEMPIPTVEAGPILYRIPIMSEPVFAELERVIKENHLQ"
     gene            57121..58572
                     /locus_tag="VCR92_000064"
     CDS             57121..58572
                     /locus_tag="VCR92_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEP4267165.1"
                     /translation="MMQPFLDIINKILGFPIQLGSGVVMLIVMTGLAMIFGVKFTKAL
                     EGGIKLAIALTGIGAIIGILTGAFSESLQAFVKNTGISLNIIDVGWAPLATITWGSPY
                     TLYFLLVMLVVNIVMIVMKKTDTLDVDIFDIWHLSITGLLIMWYADHNHLPVLVSLLI
                     ATVAVILVGVLKIINSDLMKPTFDDLLGTGSQSPMTSTHMNYMMNPIIMVLDKIFDKV
                     FPGLDKYDFDAAKLNKKIGFWGSKFFIGMALGFVIGIMGDPHFTVESIKNWFGLGFTA
                     GACLELFSLIGSWFIAAVEPLSQGITNFANARMHGRRFNIGLDWPFIAGRAEIWACAN
                     ILAPIMLIEAVLLSKVGNGILPLAGIIAMGMTPALLVVTRGRLIRMIIFGSLLLPLFL
                     LSGTMIAPFATELAKKVGAFPAGTSAGSLITHSTLEGPMEKIFGYVIGQATTGQIASI
                     ITLIIFVAIYLGLFAWYANQMKARNAEYAKTMK"
     gene            58829..59254
                     /gene="lacA"
                     /locus_tag="VCR92_000065"
     CDS             58829..59254
                     /gene="lacA"
                     /locus_tag="VCR92_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEP4267166.1"
                     /translation="MAIILGADAHGNALKELIKSFLQEEGYDIIDVTDINSDFIDNTL
                     AVAKAVNEAEGRLGIMVDAYGAGPFMVATKLKGMVAAEVSDERSAYMTRGHNNARMIT
                     IGAEIVGPELAKNIVKGFVTGPYDGGRHQIRVDMLNKMA"
     gene            59269..59784
                     /gene="lacB"
                     /locus_tag="VCR92_000066"
     CDS             59269..59784
                     /gene="lacB"
                     /locus_tag="VCR92_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEP4267167.1"
                     /translation="MKIAIGCDHIVTNEKMAVSDFLKSKGYDVIDCGTYDHTRTHYPI
                     FGKKVGEAVVNGQADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIDAFIKAEYKETEENKKLIAKIAHLESHHANQEDPDFFTEF
                     LEKWDRGEYHD"
     gene            59794..60247
                     /locus_tag="VCR92_000067"
                     /pseudo
     CDS             59794..60247
                     /locus_tag="VCR92_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="catalyzes the formation of tagatose
                     1,6-bisphosphate from tagatose 6-phosphate and ATP;
                     frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
     gene            60294..61271
                     /gene="lacD"
                     /locus_tag="VCR92_000068"
     CDS             60294..61271
                     /gene="lacD"
                     /locus_tag="VCR92_000068"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEP4267168.1"
                     /translation="MTITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEAT
                     VTQIETLKVLVSEELTPYASSILLDPEYGLLATKVRANQTGLLLAYEKTGYDATTTSR
                     LPDCLVEWSVKRLKAAGADAIKFLLYYDVDGDEQINLQKQAYIERIGSECTAEDIPFF
                     LELLSYDERISDNNSAAYAKLKPHKVNGAMSVFSDKRFGVDVLKVEVPVNMAYVEGFT
                     EGEVHYSQAEAIKAFQDQEAASHLPYIYLSAGVSAKLFQETLYFAAAAGAQFSGVLCG
                     RATWAGSVPVYITKGEDEARKWLCTEGFQNIDELNRVLEETASPWTEKI"
     gene            61468..62085
                     /locus_tag="VCR92_000069"
     CDS             61468..62085
                     /locus_tag="VCR92_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEP4267169.1"
                     /translation="MTIDMWEILNIIGTIAFALSGAIVAMEEEFDILGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQKPEFTCAFFAMVLIMLFPKLIARGWVRAVVLTDAIGLA
                     AFSVQGALHAVRLNQPLSAVIVAAVLTGAGGGVVRDILAGRKPSVLRSEIYAGWSILA
                     AIVLHFKLADSTIECYALVVLLTTLRMIGNRKKWNLPKIKWKEER"
     gene            62087..62911
                     /locus_tag="VCR92_000070"
     CDS             62087..62911
                     /locus_tag="VCR92_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEP4267170.1"
                     /translation="MIQLIAIDLDGTLLNQDKQIPKENITAIQEAAQSGLKIVLCTGR
                     PQSGTRPYFDQLGLTQEEFLIINNGCSTYSSPDWQLRHSKMLKVSDIELLEELSQSFP
                     DIYLTLTEENDYLVLEEEVPDLVQEDGDLVFTIVKPVSLAELSDTPRLIFQAMYLGEK
                     AALDAFERAVRNQLSQSFHVVRSQDNILEILPQGVSKASALKELVEDLGLTADQVMAI
                     GDAPNDIEMLTYAGLGVAMENASAAIKPLADKVTLTNDMAGVAQAIRQFALAAQKD"
     gene            complement(62947..63504)
                     /locus_tag="VCR92_000071"
     CDS             complement(62947..63504)
                     /locus_tag="VCR92_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEP4267171.1"
                     /translation="MTDKALSKRSLQNLTQFNKETRRIARESMEIALLNLLETKPLGD
                     ITISELVTKAGVSRNAFYRNYTSKEAIIEQLLVGVIRRIFRGLKQFDIKTQAYQAWLY
                     LFTEAKKEAQLLKMIFKHHLHHLLTRLVTKRLKAYQKLKDKKQSHYKRLFWSNAIVSV
                     LTNWISDDMIVPAEEMAAMGLPLLT"
     gene            63797..64639
                     /locus_tag="VCR92_000072"
     CDS             63797..64639
                     /locus_tag="VCR92_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEP4267172.1"
                     /translation="MTWKIVTDSGCDLRSLTRQSKELRFERVPLTLQIGTEIFRDDDG
                     LDIDNMMTTMYQSSKATTSSCPSPEAFLQAYRGADNVIVMTITGTLSGSHNSARLAKN
                     ELLEENPNVNIHLIDSLSAGGEMDLLVLELERLINLGLSFEEVVKQITAYQQKTRLIF
                     VLAKVDNLVKNGRLSKLVGKVIGLLNIRMVGKASNKGTLELLQKARGQKKAVSALIEE
                     IQKEGYVGGKVYIAHAQNPKICEQISEKIKSLYPDAVIQTGRTSGLCSFYAEDGGLLM
                     GYEI"
     gene            complement(64768..65490)
                     /locus_tag="VCR92_000073"
     CDS             complement(64768..65490)
                     /locus_tag="VCR92_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267173.1"
                     /translation="MATMKQYHKGDSMTKSQKEALYWMLSVLTITLIGGSCLIFGSHP
                     QTQDKVAKHSKSAASLLKKAVKAVNDADRLATAAAIQEAQKAVDKLAESSKKKTLQEQ
                     LNVAKAKQEQEDAATQAVKAAEETLNQNLKDIAQKAVNDLSNKGKKAALQSRLDAILP
                     AKPIIDEFPRQSGEITDNSYWTPFPGDVSDTYDNSQSPTLDPSSESSASDVTPQPSHP
                     DPIPPQTSSEPSDSGDKQSSKE"
     gene            65692..67323
                     /locus_tag="VCR92_000074"
     CDS             65692..67323
                     /locus_tag="VCR92_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEP4267174.1"
                     /translation="MSVNWQDIAFHFFGGLGLFLFSIKYMGDGLQQAAGDKLRYYIDK
                     YTSNPFFGILVGIAMSALIQSSSGVTVITVGLVSAGLLNLRQAIGIVMGANIGTTITS
                     FLIGFKLGDYALPMIFIGAACLFFTSNKKLNNFGRIIFGVGGIFFSLNLMGDAMDPLK
                     SVSAFQNYLATLGDKLFQGVFIGTALTMLIQSSAAIIGILQGLFSGGLLTLQGAIPIL
                     LGSNIGTCITAVLAAIGSNIAAKRVAAAHVLFNLIGTIIFMIILVPFTSLMLWLQSKL
                     SLTPEMTIAFSHGSFNITNTILLIPFISLLAMIVTRLIPGEDEVVKYEALYLDRLLIT
                     QAPSIALGNAHKELVHLASYAIQAFEASYSYIMTADGKFGEKVKRYERAVDTIDEELT
                     TYLVDISNEALSPSENEVLAGILDSSRDLERIGDHSESLGILIEGIISKQIGFSISAR
                     QELTEMYQLTHCLTLDAIRAIVDSDTDLAQTIVTRHKEIEEKERRLRKTHIKRLNCGE
                     CTAQAGINFIDIISHYTRITDHALNLAEKVLSHQL"
     gene            67440..68588
                     /gene="nagA"
                     /locus_tag="VCR92_000075"
     CDS             67440..68588
                     /gene="nagA"
                     /locus_tag="VCR92_000075"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEP4267175.1"
                     /translation="MTCYLKADCFYYPTEVKPAGYLGLHDGVFGEWTEIVPADAQIID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAQGIHQMSEGLLATGVTSFLPTTLTSTFEQL
                     EKVSGTIASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPSYMKTPRLEEFDAWQKAAK
                     GLIKKIALAPEREGVKEFVSAVTKQGVTVALGHSNGTYQEAKEAVQAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNLPNTYAELICDGHHVSPIACDILMQQKGHDHVAMITDCMRA
                     GGSPDGDYLLGEFSVVVANGTARLKESGNLAGSILKLKDGLRNVVAWGIATPAEAIHM
                     ATYVPAVSVGIDDVCGQIKAGHAADFIVLDKDLTLVATYLNGQKAFDA"
     gene            68710..69549
                     /locus_tag="VCR92_000076"
     CDS             68710..69549
                     /locus_tag="VCR92_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEP4267176.1"
                     /translation="MVTTVKMTSGYEIPVLGFGTYQAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYKNEESVGRAIKDSGVLREDLFITTKLWNDAHSYEGAKDALAASLDRLGLDYV
                     DLYLIHWPNPKALRNTWKEANAQAWQYMEEAVEAGLIKSIGVSNFMVHHLEALQETAK
                     ITPAINQIRLAPGCYQKEVVDYCKANEILLEAWSPLGQGEIFDNETMQQLANKYDKTV
                     AQVALAWSLAEGFIPLPKSVHDERIKENMAIFDVSLTQEDKKTIRYLSGMSAIPNPDT
                     TSF"
     gene            69681..70214
                     /locus_tag="VCR92_000077"
     CDS             69681..70214
                     /locus_tag="VCR92_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEP4267177.1"
                     /translation="MTIFLVMLAMFTIRLVFLKKSITNEKAILAQGGQEFGAQNTKFL
                     TLLHIMIYVFAVIEALLKQIKFDGISFLGLLLMLLSVAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTIKHPNYFLNIAPELVGIALLCHAKITAMLLFPCYIVVIYLRIREE
                     NKLLAEVIIPNGTRTKP"
     gene            70586..71503
                     /gene="glyQ"
                     /locus_tag="VCR92_000078"
     CDS             70586..71503
                     /gene="glyQ"
                     /locus_tag="VCR92_000078"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEP4267178.1"
                     /translation="MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFE
                     KFEKEASRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKKLGFPLLDEATRAILLAEDDE"
     gene            71881..73920
                     /locus_tag="VCR92_000079"
     CDS             71881..73920
                     /locus_tag="VCR92_000079"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEP4267179.1"
                     /translation="MSKNLLIELGLEELPAYVVTPSEKQLGERLATFLTENRLSFEDI
                     QTFSTPRRLAVRVSGLADQQTDLTEDFKGPAKKIALDADGNFSKAAQGFVRGKGLTTD
                     AIEFREVKGEEYVYVTKHEAGKPAKEVLLGVTEVLSAMTFPVSMHWANNSFEYIRPVH
                     TLTVLLNDEALELDFLDIHSGRVSRGHRFLGTETTITSADSYEADLRSQCVIVDAKER
                     QEMIVEQIKTLEVEQGVQVDIDEDLLNEVLNLVEFPTAFMGNFEAKYLDVPEEVLVTS
                     MKNHQRYFVVRDQAGHLMPNFVSVRNGNDQAIENVIKGNEKVLVARLEDGEFFWREDQ
                     KLQIADLVAKLTNVTFHEKIGSLAEHMDRTRVIAASLAKEANLSAEEVTAVDRAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLAGEDAAVATAIREHYLPDAAGGALPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILDHFGWRIPMDKLVDSLYD
                     LSFDSLTYTNKADVMNFIRARVDKMMGKAAPKDIREAILASSTFVVPEMLAVAEALVK
                     ASHTENYKPAVESLSRAFNLAEKADASVQVDPSLFENEQENTLFAAIQGLTLAGSAAQ
                     QLEQVFALSPVINDFFDNTMVMAEDQALKNNRVAILSDLVSKAKTIAAFNQLNTK"
     gene            74074..74331
                     /locus_tag="VCR92_000080"
     CDS             74074..74331
                     /locus_tag="VCR92_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEP4267180.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKLVDEEGNDVTPEKLRQVQREKGLHGRSLDDPKS"
     gene            74458..74850
                     /locus_tag="VCR92_000081"
     CDS             74458..74850
                     /locus_tag="VCR92_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEP4267181.1"
                     /translation="MCLSYNRRNQRKKVVLMTIKKFSLLAIASLSLLSLAACDMDDKD
                     DHMDNQPKTSQTSKKVKLSEDKAKSIALKDASVTEADAQMLSVTQDNEDGKAVYEIEF
                     QNKDQEYSYTIDANSGDIVEKSSEPIND"
     gene            75210..76736
                     /gene="glpK"
                     /locus_tag="VCR92_000082"
     CDS             75210..76736
                     /gene="glpK"
                     /locus_tag="VCR92_000082"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEP4267182.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNQKGEKVSSSQKEFPQIFPHAG
                     WVEHNANQIWNSVQSVIAGAFIESSIKPSQIEAIGITNQRETTVVWDKKTGVPIYNAI
                     VWQSRQTAPIAEQLKQDGHTKMIHEKTGLVIDAYFSATKIRWILDHVPGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKDLTWDDEILELLNIPKDMLPEV
                     KSNSEIYGKTAAFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GDEMQLSSNNLLTTIGYGINGKVHYALEGSIFIAGSAIQWLRDGLKMIETSPESEQLA
                     LASTSDDEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTSKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGIDIQQLRVDGGAAMNNMLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     AVGYWEDMDALKELNATGQLFKASMNESRKEKLYKGWKRAVKATQVFTQEEDADDDAK
                     "
     gene            76752..78590
                     /gene="glpO"
                     /locus_tag="VCR92_000083"
     CDS             76752..78590
                     /gene="glpO"
                     /locus_tag="VCR92_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEP4267183.1"
                     /translation="MEFSRETRRLALQKMQERDLDLLIIGGGITGAGVALQAAASGLD
                     TGLIEMQDFAQGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEPGSTFSMFRLKVAMDLYDLLAGVSNTPAANKVLTKEEVLKREPDLKQEGL
                     LGGGVYLDFRNNDARLVIENIKRANRDGALIASHVKAEDFLLDDNGKIIGVKARDLLS
                     DQEIIIKAKLVINTTGPWSDETRQFSHKGQPIHQMRPTKGVHLVVDRQKLPVSQPVYV
                     DTGLNDGRMVFVLPREEKTYFGTTDTDYTGDLEHPQVTQEDVDYLLGVVNNRFPNANV
                     TIDDIESSWAGLRPLLSGNSASDYNGGNSGKVSDDSFDHLVDTVKAYINHEDSREAVE
                     KAIKQVETSTSEKELDPSAVSRGSSFDRDENGLFTLAGGKITDYRKMAEGALTGIIQI
                     LKEEFGKSFKLINSKTYPVSGGEINPANVDSEIEAYAQLGTLSGLSMDDARYLANLYG
                     SNAPKVFALTRQLTAAEGLSLAETLSLHYAMDYEMALKPTDYFLRRTNHLLFMRDSLD
                     ALIDPVINEMAKHFEWSDQERVAQEDDLRRVIADNDLSALKGQQEG"
     gene            78592..79293
                     /locus_tag="VCR92_000084"
     CDS             78592..79293
                     /locus_tag="VCR92_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEP4267184.1"
                     /translation="MDIFGEFLGTALLVLLGNGVVAGVVLPKTKTHASGWIVIATGWG
                     IAVAVAVFISGKVAPAHLNPAVSLAFAMSGTIAWSTAIAYSLAQLLGAMVGSTLVFLQ
                     FRPHYLAAESQADILGTFATGPAIRDTSSNLLSEIFGTFVLMLGILAFGLYDMPAGLG
                     TLCVGTLVIGIGLSLGGTTGYAINPARDLGPRLVHAILPLNNKGDSDWSYAWIPVVGP
                     IIGAALAVLLFQVMS"
     gene            79402..80748
                     /locus_tag="VCR92_000085"
     CDS             79402..80748
                     /locus_tag="VCR92_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEP4267185.1"
                     /translation="MTLTTKTIHVIGASFAGLAFVDKYKDLNPDSQIILIDKESCPNY
                     IPNGINQLFRGDIQDLSDAMWGRACLAAQIESNHRFIQAEVLAIEAPSNTLLLKDSQG
                     RVFEEGYETLVCAMGASPQSHYIETSQTNKVLVTKYYEESQASLKLIEASQEVLVIGA
                     GLIGLDLAYSLSLQGKRVKLIEAAERPDFYQTDAELIAPVMAEMSTHHVTFINNKRVT
                     AIHEIEGKVVAHTEQGDTFQGDLAILAINFRPNTHLLQGQVACALDKTILVNENLQTS
                     QANIYAIGDMVSLYFGILGMDYYTPLINQAMKTGQALALHLAGYPIPPLQTVKVLGSS
                     HFGYYRASVGVTEEEAELYMDTCSYLYQNGDSKNLFWLKLIARKTDGILIGAQLLSKT
                     NALVIANQLGQALALKVTDGDLAFQDFLFLQGHSDLAYHLHEACLKLFEKRLRHED"
     gene            80738..82237
                     /locus_tag="VCR92_000086"
     CDS             80738..82237
                     /locus_tag="VCR92_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP4267186.1"
                     /translation="MKIEDLMDKERKAQYRLLVTLYHAKETLRLKDLMRLSNLSKVTL
                     LKYIDNLNHLCREQGLACQLLLEKDSLSLKENGQFHWEDLVALLLKESVAYQILTYMY
                     CHEHFNITNLSVELMVSEATLNRQLAHLNQLLSEFDLALSQGRQLGSELQWRYFYLEL
                     FRHTLTRQGIDALVNQLDASHLATLIERLIGQSLSAEALEQLLIWLAISQARMSFQKG
                     YNDHFLRDSDFMTSNIFFKRLESMLLHYLRRYALEFDAFEAKSLFVFLHAYPLLPIAS
                     MKYSLGFGGPIADHISEALWLLKKAHVIIHQTKEEIIYGLGIFFSKAYFFKGAILSQP
                     TNSQYLYQLVGEDKRALLRVIINHLVLQMGQETDFSQQLSDDILALLVFSIERHHEPL
                     LVGLALGQNKVEAAIAELAIRRHLGHRRDFQLMPYDHQKVYDCLITYQTVYLPRQDLP
                     YYRLKQYSSPYELTALEAFLKDLFQQKNTREEELSLSPAAKSSFAHKTV"
     gene            82363..83007
                     /gene="fsa"
                     /locus_tag="VCR92_000087"
     CDS             82363..83007
                     /gene="fsa"
                     /locus_tag="VCR92_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEP4267187.1"
                     /translation="MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIK
                     EICDIVDGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREIIDLYDFQAEI
                     IAASIRTTAHVEAVAKLGAHIATIPDPLFAKMTQHPLTTNGLKTFMEDWASFKK"
     gene            83225..85210
                     /gene="tkt"
                     /locus_tag="VCR92_000088"
     CDS             83225..85210
                     /gene="tkt"
                     /locus_tag="VCR92_000088"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013793690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEP4267188.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLHLAGYDLSVEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVNHYTFALNGDG
                     DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEEIAAAIEAAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAVYEAEYPELAAEYQKAF
                     TNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETD
                     FQPGHYEGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQN
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNFNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLEGILIATGSEVKLAMDT
                     QEALEAEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVANATELYKSL"
     gene            85403..85669
                     /locus_tag="VCR92_000089"
     CDS             85403..85669
                     /locus_tag="VCR92_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEP4267189.1"
                     /translation="MEKKRQRLYDVIRQAYDYPENRENVALSQLLLAASNRLIKHSNP
                     LLVAYQLNQDVDNYLLDNDILLPKSLCRFKQSLEKYILEEASSV"
     gene            85703..86437
                     /locus_tag="VCR92_000090"
     CDS             85703..86437
                     /locus_tag="VCR92_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4267190.1"
                     /translation="MIEFKHVSKLYGDKEALSDLNVTINDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYGEVFVDGQLLTENREAIKKQIAYVPDSPDIFLNLTPNEYWQFLAKIY
                     GVSDEDREERLAQLTTLFELKEEVNQTIDSFSHGMRQKVIVIGALVSNPNIWILDEPL
                     TGLDPQASFDLKEMMKAHAASGHTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTIDE
                     LKEHHPDKDLESIYLELAGRKAQEEG"
     gene            86442..88070
                     /locus_tag="VCR92_000091"
     CDS             86442..88070
                     /locus_tag="VCR92_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4267191.1"
                     /translation="MNWSTIWELIKINILYSNPQSLANLKKRQENHPKENFKAYKSMM
                     RQQALMIAMFLVIYLFMFIGVDFSHYPGLFSFDVAMFFIMSTLTAFSSLYTIFYESND
                     LKLYIHLPVTSEELYIAKIVSSLGMGAVFLMPLISLLLIAYWQLLGNPLSILVAIVLF
                     LVLLVSSMVLAIYINAWVGKIIVRSRKRKLISTIMMFVSTFGAFVLIFAINISNNKRT
                     MTDGVFTDYPTIPYFKGFYDVIQAPFSTAALLNFWLPLLLILAMVYGIVTKVMPTYYR
                     EAFYISNENKAKQTKKPVNRPHQNQSLTQLLRKHHLLTLQNATLLTQTYLMPLMYVML
                     FIGPSLSRGTGFFKHISPDYFGVALLFGVSLGVMCATPTSFIGVGISLEKDNFTFIKS
                     LPITLKKFLLDKFCLLVGLQLIVPMVIYLVFGLFVLHLHPLLTIAFCLGYALSLIVQG
                     ELMYRRDYRLLDLKWQDMTQLFTRGNGQWLTMGLIFGNLIVTGVVGFGAVIIANIIQQ
                     PLLISILLSCLTLMVLGIAHLWIQKTFWKSLEKL"
     gene            88134..88955
                     /gene="proB"
                     /locus_tag="VCR92_000092"
     CDS             88134..88955
                     /gene="proB"
                     /locus_tag="VCR92_000092"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEP4267192.1"
                     /translation="MMKRQFEDVTRIVIKIGTSSLVLPTGKINLEKIDQLAFVISSLM
                     NKGKEVILVSSGAMGFGLDILKMEKRPTNLAKQQAVSSVGQVAMMSLYSQIFAHYQTN
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHATKFGDNDR
                     LSAVVAGITKADLLIMLSDIDGLFDKNPTIYEDAQLRSHVAVITQEIIASAGGAGSKF
                     GTGGMLSKIQSAQMVFENKGQMVLMNGANPRDILRVLEGQPLGTWFKQIEEVTHD"
     gene            88948..90198
                     /locus_tag="VCR92_000093"
     CDS             88948..90198
                     /locus_tag="VCR92_000093"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEP4267193.1"
                     /translation="MTDMRRLGQRAKQASLLIAPLSTQIKNRFLSTLAKALVDDTQTL
                     LAANQKDLANAKEHGISDIMMDRLRLTSERIKAIAQGVQQVADLADPIGQVIKGYTNL
                     DGLKILQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALHSNKALVKL
                     IRQSLEKSGITPDAVQLVEDPSHAVAEELMQATDYVDVLIPRGGAKLIQTVKEKAKVP
                     VIETGVGNVHIYVDAQADLDMATNIVINAKTKRPSVCNAAEGLVIHEAVAARFIPMLE
                     KAINQVQPVEWRADDKALPLFEQAVPAKAEDFETEFLDYIMSVKVVSSLEEAISWINQ
                     HTSHHSEAIITRDIKAAETFQDLVDAAAVYVNASTRFTDGFVFGLGAEIGISTQKMHA
                     RGPMGLEALTSTKFYINGDGHIRE"
     gene            90218..90439
                     /locus_tag="VCR92_000094"
     CDS             90218..90439
                     /locus_tag="VCR92_000094"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267194.1"
                     /translation="MTNEREKEEAKVALEELLHQIQVIHLELKIVRNWGYFDLFGDGM
                     LVSWIKRRKMSKVNQLLIDLQVTLQNCRR"
     gene            90482..90646
                     /locus_tag="VCR92_000095"
     CDS             90482..90646
                     /locus_tag="VCR92_000095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267195.1"
                     /translation="MSWDKIFDIWLDNLLTDCCVIKEAKNFLQVVEILEAAAKSVLAK
                     LADSEQKEQD"
     gene            90670..91683
                     /gene="rsmH"
                     /locus_tag="VCR92_000096"
     CDS             90670..91683
                     /gene="rsmH"
                     /locus_tag="VCR92_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEP4267196.1"
                     /translation="MKSFSLTFSFLNLLKYGTIKVMTKEFHHVTVLLHETVDMLDIKP
                     DGIYVDATLGGSGHSAYLLSKLGEEGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTFIK
                     DNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLDMRMDRQSLLT
                     AYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIKPIETTTELAELIKAAKPA
                     KELKKKGHPAKQIFQAIRIEVNDELGAADESIQDAMELLALDGRISVITFHSLEDRLT
                     KQLFKEASTVDVPKGLPLIPEDMKPKFELVSRKPILPSHSELTANKRAHSAKLRVAKK
                     IRK"
     gene            91688..92011
                     /gene="ftsL"
                     /locus_tag="VCR92_000097"
     CDS             91688..92011
                     /gene="ftsL"
                     /locus_tag="VCR92_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEP4267197.1"
                     /translation="MTNEKRTQAVTNALQKRIKTFSRIEKAFYTAIIVTAITMAVSII
                     YLQSRKLQLQQEITSLNSHISDQKLELNNAKQEVNELSRRDRIIDIAGKAGLSNRNNN
                     IKKVE"
     gene            92015..94270
                     /locus_tag="VCR92_000098"
     CDS             92015..94270
                     /locus_tag="VCR92_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEP4267198.1"
                     /translation="MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIIN
                     FMIIIGTDQKFGVSLSEGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSASDEKLYVQPSQYETVADILKKHLGMKKTDVIKQLKRKGLFQVSFGPSGSGIS
                     YSTMSTIQKAMEDAKIKGIAFTTSPGRMYPNGTFASEFIGLASLTEDKKTGVKSLVGK
                     TGLEASFDKILSGQDGVITYQKDRNGTTLLGTGKTVKKAIDGKDIYTTLSEPIQTFLE
                     TQMDVFQAKSNGQLASATLVNAKTGEILATTQRPTYNADTLKGLENTNYKWYSALHQG
                     NFEPGSTMKVMTLAAAIDDKVFNPNETFSNANGLTIADATIQDWSINEGISTGQYMNY
                     AQGFAFSSNVGMTKLEQKMGNAKWMNYLTKFRFGFPTRFGLKDEDAGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNNGEMLEPQFISQIYDPNTASFRTANKEIVGKPVS
                     KKAASETRQYMIGVGTDPEFGTLYSKTFGPIIKVGDLPVAVKSGTAQIGSEDGSGYQD
                     GGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHFGPLFWQDVVNPVLEEAYLMQDTLTK
                     PVVSDANRQTTYKLPNFVGKNPGETSSELRRNLVQPVVLGTGSKIKKVSHQPGQTLTE
                     NQQVLILSDRFVEVPDMYGWTKSNVKTFAKWTGIDISFKGTDSGRVMKQSVDVGKSLK
                     KIKKMTITLGD"
     gene            94272..95282
                     /locus_tag="VCR92_000099"
     CDS             94272..95282
                     /locus_tag="VCR92_000099"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEP4267199.1"
                     /translation="MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDDFL
                     KIFKQINEGLTAKQKLALQLVGGLMFYFLHVSPSGISSINVFGYQLPLGIFYLFFVLF
                     WVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQSQFDVLLLIGAMIGALLGFFC
                     FNHKPAKVFMGDVGSLALGAMLAAISIALRQEWTLLIIGIVYVLETSSVMLQVSYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILY
                     VF"
     gene            95440..96783
                     /locus_tag="VCR92_000100"
     CDS             95440..96783
                     /locus_tag="VCR92_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEP4267200.1"
                     /translation="MSFKDYHFKQYVQQALEEIGFVNPTEVQKRLIPIVNSGRDLVGE
                     SKTGSGKTHTFLLPIFEKLDEAKAEVQVVITAPSRELATQIFDACKQIAKHFQEEIRL
                     ANYVGGTDKLRQIEKLKGSQPHIVIGTPGRIYDLVKSGDLAIHKATTFVVDEADMTMD
                     MGFLDTVDKIAASLPKSVQILVFSATIPQKLQPFLKKYLTNPVIEQIKTKTVIADTID
                     NWLVSTKGRDKNGQLLEILKTMQPYMAMLFVNTKERADDLHAFLTANGLKVAKIHGGI
                     PPRERKRIMNQVKKLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGMAGTAITLYQPSDDSDIKELEKMGIAFTPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKERRAENRAKGRAERNAKKQHF"
     gene            96978..97781
                     /locus_tag="VCR92_000101"
     CDS             96978..97781
                     /locus_tag="VCR92_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEP4267201.1"
                     /translation="MTSVFLTSGWAFYDYLISPIPHGKLFSWHAVFDAIPNIIQRLPI
                     TLGLTLSGATFGLVLALIFALVKINKVKLLYPIQAIFVSFLRGTPILVQLMLTYYGIP
                     LFLKFLNQKYGFDWNVNAIPASIFAITAFAFNEAAYASETIRAAILSVDTGEIEAAKS
                     LGMTSVQVYRRVIIPNATVVAIPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGSD
                     YRYFERYISVALVYWSISILMEQVGRLIENKMAIKAPEQARNEKLGELR"
     gene            97781..98524
                     /locus_tag="VCR92_000102"
     CDS             97781..98524
                     /locus_tag="VCR92_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEP4267202.1"
                     /translation="MITIRNLSKTFSGQKVLDSLALDIEKGQVIALVGASGAGKSTFL
                     RSLNYLEKPDSGSISIGDFTVDFETITTEQVLILRRKLAMVFQQFNLFERRTALENVK
                     EGLKVVKKLSDQEATKLAQAELAKVGLADRKHHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSITDAAKSGQTMVLVSHDMNFVYQVADRVLFLDQGKIL
                     EQGTPEEVFRHPQKERTKEFFASYSKTYI"
     gene            98628..98852
                     /locus_tag="VCR92_000103"
     CDS             98628..98852
                     /locus_tag="VCR92_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEP4267203.1"
                     /translation="MLVEIFSLYVKGLILSSLTMILICLIWTLWRAKTKRDKTLIERQ
                     AFLYEMLMVAILTIPILSFAFMSILVVIKS"
     gene            98916..99833
                     /gene="trxB"
                     /locus_tag="VCR92_000104"
     CDS             98916..99833
                     /gene="trxB"
                     /locus_tag="VCR92_000104"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEP4267204.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNTFD
                     IENYPGYDHISGPELAMKMYEPLEKFNVENIYGIVQKIENFGDYKCVLTEDASYEAKT
                     VIIATGAKYRVLGVPGEEYYTSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEAIYLT
                     QFAKKVTVVHRRDQLRAQKILQDRAFANDKVDFIWDSVVKEIQGNDIKVSNVLIENVK
                     TGQVTDHAFGGVFIYVGMNPVTGMVKDLEITDQEGWIITDDHMRTSIPGIFAIGDVRQ
                     KDLRQITTAVGDGAIAGQGVYHYLESFPS"
     gene            100002..101381
                     /locus_tag="VCR92_000105"
     CDS             100002..101381
                     /locus_tag="VCR92_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEP4267205.1"
                     /translation="MSIKEQTDNNELENGMVRGLENRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGAFMFMMMRAIGEMLYYDPDQHTFINFISKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVGAYVQFWFPSWPAWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKILAILALIATAIFMVLTGFETHTGHASLSNIFDHLSMFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPTRIVIFYVGALVSIMAIVPWHQLPVDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTNRLK
                     INTLSRQGVPSRAIIASAVVVGISALINILPGVADAFSLITASSSGVYIAIYALTMIA
                     HWKYRQSKDFMADGYLMPKYKVTTPLTLAFFAFVFISLFLQESTYIGAIGATIWIIVF
                     GIYSNVKFK"
     gene            101552..103006
                     /locus_tag="VCR92_000106"
     CDS             101552..103006
                     /locus_tag="VCR92_000106"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEP4267206.1"
                     /translation="MYKDDSLTLHTDLYQINMMQVYFEQGIHNRHAVFEVYFRKEPFN
                     NGYAVFAGLQRMVEYLEQFQFSETDLAYLEELGYPGNFLTYLKELRLELTIRSAKEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQELDAAIWGTRAAMIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFMAYA
                     KTHKDCVFLVDTYDTLKVGVPTAIRVAKEMGDKINFLGVRLDSGDLAYLSKTVRQQLD
                     DAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QEDGSMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTDINVNELTEIEM
                     FHPTYTYIKKTVRNFDAIPLLVDIFVKGELVYQLPTLSEIKTYAKKEFDKLWDEYKRV
                     LNPQDYPVDLARDVWQNKMTLIDNIRKDTHGKSE"
     gene            103008..103832
                     /gene="nadE"
                     /locus_tag="VCR92_000107"
     CDS             103008..103832
                     /gene="nadE"
                     /locus_tag="VCR92_000107"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEP4267207.1"
                     /translation="MTLQEEIIRQLGVKASIDPQEEIRKTVDFLKAYLRKHSFLKTYV
                     LGISGGQDSTLAGKLAQMAIAELREETSDQAYQFIAVRLPYGVQADEADAQKALAFIA
                     PDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQYAIAGQMAGAVIGT
                     DHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQK
                     PGLADEVALGVTYQDIDDYLEGKLISKAAQATIEKWWHKGQHKRHLPITIFDDFWK"
     gene            104017..105354
                     /gene="pepC"
                     /locus_tag="VCR92_000108"
     CDS             104017..105354
                     /gene="pepC"
                     /locus_tag="VCR92_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEP4267208.1"
                     /translation="MSALTETFTEQLFAHYEANAKFSAIENAVTHNGLLKSLETRQSE
                     VDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLITEFKLENFELSQAHTFFWD
                     KYEKANWFMEQVIATADQELTSRKVKFLLDVPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESISSSNSRELNQYLNKLLRQDAQILRDLIASGAKADQVEDRKAELLQEIFNFLAMTL
                     GLPPRHFDFAYRDKDDHYHVEKGLTPQAFYDKFVGLKLSDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSREVRYLNLDMKRFKELAIKQMQAGESVWFGSDVGQVSDRQKGILATN
                     TYDFEASMDINLSQDKAGRLDYSESLMTHAMVLTGVDLDETGKPLKWKVENSWGEKVG
                     DKGYFVASDAWMDEYTYQIVVRKEFLTADELAAYEKEPQVLAPWDPMGALAQC"
     gene            complement(105818..107983)
                     /locus_tag="VCR92_000109"
     CDS             complement(105818..107983)
                     /locus_tag="VCR92_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEP4267209.1"
                     /translation="MITIKNPKILKWLKYVLSAILSLIILVIIIGGLLFTFYISSAPK
                     LSEAQLKSTNSSLVYDGNNNLIADLGSEKRENVTADSIPINLVNAITSIEDKRFFNHR
                     GVDLYRIFGAAFHNLTSQTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKSYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYLHPEAAQNRRNVVLQQMYMEKHLTKAEYETAIATPVAEGLQSLQQRSTYPKYMD
                     NYLKQVIEEVKKETNKDIFTAGLKVYTNIIPDAQQTLYNIYHSGDYVYYPDQDFQVAS
                     TIVDVTNGHVIAQLGGRNQDENVSFGTNQAVLTDRDWGSTMKPITAYAPAIESGVYTS
                     TAQSTNDSVYYWPGTTTQLFNWDLRYNGWMTIQAAIMLSRNVPAVRALEAAGLDYARS
                     FLSSLGINYPEMHYSNAISSNNSSSDKKYGASSEKMAAAYAAFANGGIYHKPRYVNKV
                     EFSDGTSKTFDEKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAKIGEKYGLYPDYVGTLAPDENFVGFTKRYAMAVWTGYKNRLTPVYGSSLEIA
                     SDVYRSMMTYLTNGYSEDWTMPNGLYRSGGFLYLSGTYASNTDYTNSVYNNLYSNNTT
                     TASSQTTSDDTSSSNDISNSTNTDNNSNHPSTDDKKTTH"
     gene            complement(107970..108578)
                     /gene="recU"
                     /locus_tag="VCR92_000110"
     CDS             complement(107970..108578)
                     /gene="recU"
                     /locus_tag="VCR92_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEP4267210.1"
                     /translation="MVNYPHNLIRQKVSSVQKQTKQNKVDFANRGMSFEAAINATNDY
                     YLSRQIAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYCGVYKGHYVDFEAK
                     ETRQKTAMPMKNFHLHQIEHMACVLHQKGICFVLLHFSTLKETYYLPAQALISFYQID
                     NGSKSMPIDYIRKNGFKVAFGAFPQVPYLNIIEQNFLGGDYN"
     gene            108659..109174
                     /locus_tag="VCR92_000111"
     CDS             108659..109174
                     /locus_tag="VCR92_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEP4267211.1"
                     /translation="MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVD
                     WFIFTGNLGFEQWALEVANELKEEYPLQIATIFLFETHGDRWNEKNQEVLSQFRAVDF
                     VKYYFPNYEQPTQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPHYQLLLL
                     TFDRLNDMSQS"
     gene            109296..109622
                     /gene="gpsB"
                     /locus_tag="VCR92_000112"
     CDS             109296..109622
                     /gene="gpsB"
                     /locus_tag="VCR92_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEP4267212.1"
                     /translation="MTSIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYENFNA
                     QIEALKAENEALKKAKFQARNTVSATVQQPVPQPTRVAQSATNFDILKRISKLEKEVF
                     GKQIIE"
     gene            109636..110004
                     /gene="rnpB"
                     /locus_tag="VCR92_000113"
     ncRNA           109636..110004
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VCR92_000113"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            110067..111221
                     /locus_tag="VCR92_000114"
     CDS             110067..111221
                     /locus_tag="VCR92_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEP4267213.1"
                     /translation="MKETFRLVATAAAGLEAVVGKEVRALGFDCQVENGKVYFEGDVE
                     AIVKTNLWLRAADRIKIIVGQFPARTFEELFQGVFALDWGNYLPLGAKFPISKAKCVK
                     SKLHNEPSVQAITKKAVVKKLQKHFHRPEGVPLQEVGSTFNIEVSILKDQATIMIDTT
                     GSSLFKRGYRVQKGGAPIKENMAAAILALSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDMVQQVRDDAEQEANYEIELDISGFDIDGRMIEIAKSNA
                     EEAGLSDVITFKQMRLQDFRTDKVNGVVISNPPYGERLLDDKAVDILYNEMGQTFAPL
                     KTWSKFILTSDELFELKYGQKADKKRKLYNGTLKVDLYQFYGERVKRHLI"
     gene            111235..112704
                     /locus_tag="VCR92_000115"
     CDS             111235..112704
                     /locus_tag="VCR92_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267214.1"
                     /translation="MSEESKEVEVTKESQTLGLNEAKSMTIGEAVRKQSEIKAGVTKD
                     DSILDKYIKQHRDEVSSQKFDAKYTELDTASLDNFIKKQREALSKAGLVDDEPVSAES
                     AEQDSTLVEEVAEDLAPMETTAVVTGIPVEATVPVLDLDPSERGIPEPQMTKEEPKRD
                     QFLSEDSHHPAKQNTKKGWLIALFLLLLAILAVVFGWNHFLRQDSGKTTQTASKQTKT
                     SLQTDSAKKATRLKAAAKAFEKQYGTFYTDATKSKLKNSAFATLPDLEAALKALEGSA
                     YYDKAKAKVDSLKKAIAAITAVNGKFVSDVVVDGEKVSAEVKADANFDDLSSATLTTG
                     NANLDAVLQASITEGRQQLASKAEAAKAANEQAAQAQAAQGQSTSVAPSGYGLTSYDP
                     ASLQRHLSRVPYNQDVIADRANPSWAFNPGVLEKIVATSQARGYISGYQYILEPVNII
                     NGNGYYNMFKPDGTYLFSINCKTGYFVGNGKGYADALDY"
     gene            complement(112850..113332)
                     /locus_tag="VCR92_000116"
     CDS             complement(112850..113332)
                     /locus_tag="VCR92_000116"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEP4267215.1"
                     /translation="MTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLV
                     QPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKV
                     IKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGISDDPFSRHVI
                     "
     gene            complement(113406..114737)
                     /locus_tag="VCR92_000117"
     CDS             complement(113406..114737)
                     /locus_tag="VCR92_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEP4267216.1"
                     /translation="MEIIGSLGVLIGVIVIIYLSVKEVNIIIAAPLATSLVILFNQMD
                     PTTTLLGKEPNQFMGALSTYILNYFAIFLLGSILAKLMETSGETTSIADYILKKVGHD
                     SPYKVLVAIFLISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLDTSLTAAAIPSIVGSIGCVTFGLFYMKYCLAKSMARG
                     ETYATYAFDNEIQVKTKNLPHFLASILPLLLLIIIALTGSLFGNDFFKKNIIFIALLA
                     AILTASWLFRQFIPNKIAVFNLGASSSIAPIFATASAVAFGAVVMIAPGFTFFSDLIL
                     NIPGNPLISLAVLTSSMSAITGSSSGALGIVMPNFAQYYLDQGLNPEMIHRVATIASN
                     IFTIVPQSGVFLTFLALTGLNHKNAFKETFITVSVSTFIAQVIMIAFDLFS"
     gene            complement(114808..115587)
                     /locus_tag="VCR92_000118"
     CDS             complement(114808..115587)
                     /locus_tag="VCR92_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEP4267217.1"
                     /translation="MTHTKEVAFITGAASGIGKQIGETFLKEGKTVVFSDINQEKLDQ
                     VVADYTKEGYDAFSVVCDVTKEEAINAAIDTVVEKYGRIDILVNNAGLQHVAMIEDFP
                     TEKFEFMIKIMLTAPFIAIKRAFPTMKAQKHGRIINMASINGVIGFAGKSAYNSAKHG
                     LIGLTKVTALEAADSGITVNAICPGYVDTPLVRGQFEDLSKTRGIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGVTGQACILDGGYTAQ"
     gene            complement(115620..116279)
                     /locus_tag="VCR92_000119"
     CDS             complement(115620..116279)
                     /locus_tag="VCR92_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEP4267218.1"
                     /translation="MGTSATVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANY
                     IPEGVTITLQSENGFVGLTGLTDDHYDPSIVNAGGQPVSIAPGGAFFDSSTSFGIIRG
                     GHVAATVLGALQVDKEASIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAK
                     ILDKCTLPLTAQNVVNLIITEMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKT
                     N"
     gene            complement(116281..116931)
                     /locus_tag="VCR92_000120"
     CDS             complement(116281..116931)
                     /locus_tag="VCR92_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEP4267219.1"
                     /translation="MCKEITIKEAVAHVKDGDTIMVGGFMTNGTPEKLIDTLVEKGVK
                     DLTLICNDAGFPDKGVGKMVANKQFSTIIASHIGLNREAGRQMTEGETVIDLVPQGTL
                     AERIRSGGFGLGGFLTPTGIGTEVAKGKEVITVDGKDYLLEKPLKADIALIFANKADK
                     NGNLQYAGSENNFNHVMAANAKTTIVEAREIVDVGQMDPNFVHTPGIFVNYLVKGA"
     gene            complement(116955..118142)
                     /locus_tag="VCR92_000121"
     CDS             complement(116955..118142)
                     /locus_tag="VCR92_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEP4267220.1"
                     /translation="MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVK
                     PEMVDEVILGNVLHAGLGQNVARQVAVHSGIPEDKTAFTLDMVCGSGLKAIQLAAQSI
                     MLGDADIVIAGGVENMSQAAYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGIT
                     AENVAQKYGISREEQDQFALESQEKAAKALENHRFADEIVPVSVPQRRKDPLIVTTDE
                     YPKVDTSLEKLQQLRPAFLPKEGTVTAGNASGINDGAALLMLMTEEKALELGLTPLVT
                     IESYASAGVAPELMGTGPIPATQKALKKAGLTISDLDLVESNEAFAAQSLAVLKDLKL
                     NPEIVNVNGGAIALGHPIGASGARILVTLIHEMKKRQVTRGLATLCIGGGQGTAVIVK
                     NNT"
     gene            118343..119239
                     /locus_tag="VCR92_000122"
     CDS             118343..119239
                     /locus_tag="VCR92_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEP4267221.1"
                     /translation="MDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRE
                     NVKLFKRKRGRIIGLTYLGDNYYKDAQKVLSLYDDMFLKLHDHSKGLKGSISIGIPPL
                     ILSVVFSEVMPKLILENPGIQFNVKEIGAYQLKNELLVGNVDVAVLLSPTGIADNLVE
                     TYEIQRSELSVCLSPRHRLASKKVIQWEDLTDEQLALFDPSFMVHHLVLEACERHQVR
                     PNIILTSSSWDFMLNSTKINHNVLTICPKPITELYQFKDIKCILMERPISWRVVLTRL
                     RKKSYSEIEAYIMDDLLQSFFK"
     gene            119369..120976
                     /locus_tag="VCR92_000123"
     CDS             119369..120976
                     /locus_tag="VCR92_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEP4267222.1"
                     /translation="MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEA
                     VDIRGKAEVDAEHIKKTAKRESKANRKELLLEAKEEARKYREEIEQEFKSERQELKQL
                     ETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQLQVEKLEEEKKAELE
                     KVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTVKTAKDLLAQAMQRLAG
                     EYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVILSGFDPI
                     RREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDL
                     IKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDRE
                     VEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGARN
                     ESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQPEKISDDQVVILSHKVRE
                     KIENNLDYPGNIKVTVIREMRAVDYAK"
     gene            121086..121721
                     /gene="gmk"
                     /locus_tag="VCR92_000124"
     CDS             121086..121721
                     /gene="gmk"
                     /locus_tag="VCR92_000124"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEP4267223.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKSKVPDGVFVFLTPPDLDELEDRLVGRGTDSQEVIAQRIERAKEEIALM
                     REYDYAVVNDEVALAAERVKRIIETEHFRVERVIGRYDKMIKITKNPFKAK"
     gene            121737..122054
                     /locus_tag="VCR92_000125"
     CDS             121737..122054
                     /locus_tag="VCR92_000125"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEP4267224.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQEFKSV
                     KSTLQALEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEEEG
                     EKI"
     gene            122119..124503
                     /locus_tag="VCR92_000126"
     CDS             122119..124503
                     /locus_tag="VCR92_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEP4267225.1"
                     /translation="MEKVAHVIVDIPLMQTDKPFSYGIPKELVSLVQLGSRVHVPFGK
                     GNRLLQGFVIGFGQEDSSSLKLIQTVLDPEPVLNQEQLTLADQLRKTVFSYKITLLKA
                     MIPNLLNSNYDKVLRPESGLKKPDRDFLFEGKPSVLYSTLDREKEKIALKGIQAGHIT
                     VSYLAKDKKNLKTEKYYHVDLDALAVHPISSRAKKRQLLKDYLLTHTKEAKLATLYQA
                     FSRDVVAYFVTNHLIRIDERQIDRSEPYFDQIKPSSFLTLNEQQASAVTEIVEQIGKP
                     SKPFLIEGITGSGKTEVYLHIIEAVLKQDKTAIVLVPEISLTPQMTSRFISRFGKQVA
                     IMHSGLSDGEKFDEWRKIKTGQAKVVVGARSAIFSPLERIGAIIIDEEHESTYKQESN
                     PRYHAREVALLRAKHHQAVVVMGSATPSIESRARASKGVYHFIQLTKRANPLAKIPEV
                     TIVDFRDYIGQQAVSNFTPYLIDKIKERLVKKEQVVLMLNRRGYSSFVMCRDCGYVDK
                     CPNCDISLTLHMDTKTMNCHYCGFQKPIPITCPECHSNSIRYYGTGTQKAFDELQGVI
                     PEARILRMDVDTTRKKRSHKTILDSFGRQEADILLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLNLPDFRASEKTFQLLTQVAGRAGRAHKPGEVLIQTYNPDHYAIQLAKQQDFEAFY
                     RYEMAIRRQMAYPPYYFTVGITLSHRLEASVVKKAYQVTELLKSHLSDNIKILGPTPK
                     PIARTHNLYHYQILLKYRFEDNLEETLNRILDWSQEADNRHLKLIIDCEPQQFL"
     gene            124565..125500
                     /locus_tag="VCR92_000127"
     CDS             124565..125500
                     /locus_tag="VCR92_000127"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEP4267226.1"
                     /translation="MIKLLFMGTPQFSATVLKGLLDNPAYEILGVVTQPDRAVGRKKD
                     IKVTPVKQLALEHGISIYQPEKLSGSQELIEIMELGADGIITAAFGQFLPTILLDSVS
                     FAINVHASLLPKYRGGAPIHYAIMNGDKEAGVTIMEMIKEMDAGDMVAKASTPILETD
                     NVGTLFEKLAIIGRDLLLDSLPAYLSGELKPIPQDHSQATFSPNISPEQEKLDWTMSD
                     QEVFNHIRGMNPWPVAHTFLEGQRLKIYEAQLAEGEGLPGQVIVKTKKSLVIAAGQGA
                     LSLLVVQPAGKPKMAIADFLNGLGRKLEVGDFIGR"
     gene            125490..126812
                     /gene="rsmB"
                     /locus_tag="VCR92_000128"
     CDS             125490..126812
                     /gene="rsmB"
                     /locus_tag="VCR92_000128"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEP4267227.1"
                     /translation="MADNWKISIRGKALLTLEHIFDQGAYTNIALNQQLSNKALSAKD
                     RALLTEIVYGTVSRKISLEWYLAHYVKDRDKLDKWVYYLLMLSLYQLIYLDKLPAHAI
                     VNDAVGIAKNRGNKKGAEKFVNAILRQFTSHPLPDMETIKRRNKYYSVKYSLPVWLVK
                     KLEDQFGSDRSVAIMESLFVRSKASIRVTDPLKLEEAAEALDAERSLLSATGLTKASG
                     HFAASDYFTNGDITIQDESSQLVAPTLNIDGDDIILDACSAPGGKTSHIASYLKTGKV
                     IALDLYDHKLELVKENANRLGVADNIETRKLDAREVHRHFEKDSFDKILVDAPCSGIG
                     LIRRKPDIKYNKESQDFNALQAIQLEILSSVCQTLRKGGIITYSTCTIFDEENRQVIE
                     AFLQSHPNFEQVKLNHTQADIVKDGYLIITPEQYQTDGFFIGQVRRVL"
     gene            126850..127590
                     /locus_tag="VCR92_000129"
     CDS             126850..127590
                     /locus_tag="VCR92_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEP4267228.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIRDWLFETIQSENQRIYDLGQSEDFKGMGTTVE
                     AVALVESSAIYAHIGDSRIGLVHDGHYTLLTSDHSLVNELVKAGQITEEEAASHPQRN
                     IITQSIGQASPVEPDLGVRVLEPGDYLVINSDGLTNMISNDEIVTILGSKVSLDEKNQ
                     EMIDLANLRGGLDNITIALVHNESEDVE"
     gene            127587..129485
                     /gene="pknB"
                     /locus_tag="VCR92_000130"
     CDS             127587..129485
                     /gene="pknB"
                     /locus_tag="VCR92_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEP4267229.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGADLKRYI
                     QNHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIEENHNVPQALENVVIRATAKKLSDRYGSTFEMSRDLMTALSYN
                     RSRERKIVFEDVESTKPLPKVASGPTASVKLSPPTPTVLTQESRLDQTNQTDALQPPT
                     KKKKSGRFLGTLFKILFSFFIVGVALFTYLILTKPTSVKVPNVAGTSLKVAKQELYDV
                     GLKVGKIRQIESDTVAEGNVVRTDPKAGTAKRQGSSITLYVSIGNKGFDMENYKGLDY
                     QEAMNSLIETYGVPKSKIKIERIVTNEYPENTVISQSPSAGDKFNPNGKSKITLSVAV
                     SDTITMPMVTEYSYADAVNTLTALGIDASRIKAYVPSSSSATGFVPIHSPSSKAIVSG
                     QSPYYGTSLSLSDKGEISLYLYPEETHSSSSSSSSTSSSNSSSTNDSTAPGSNTELSP
                     SETTAQTP"
     gene            129608..130300
                     /locus_tag="VCR92_000131"
     CDS             129608..130300
                     /locus_tag="VCR92_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEP4267230.1"
                     /translation="MKKFQFFLLIECILLAMGIMTILDNDLSSFILILVLILLALRFY
                     NQDSRNNFLLTVSLLFLFLIFMLNPYIIMAVLLGIVYIFINHFSQVKKKNRFALIRFK
                     EEKIEVNNTKHQWIGTANYESDYYCFDDINIIRISGNDTVDLTNVIVTGMDNIIVIRK
                     IFGNTTILVPIDVTVTLDVSSIYGSVDFFRCQQYDLRNESIKLKETDNQSLKKVKIIV
                     TTIAGNVEVDRR"
     gene            130297..131301
                     /locus_tag="VCR92_000132"
     CDS             130297..131301
                     /locus_tag="VCR92_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP4267231.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFNYLRNHLWQVER
                     LGFSILLLIVSVTLLLLLLWIIMDDNSKRNINQNLKYILNNRRLYLDETSEINTNLSR
                     LSKKMSHLTANMQKKESAYILDSQEVVKQERKRIARDLHDTVSQELFASSLILSGISM
                     SLEQLDKTQLQTQLTTVEAMLQNAQNDLRILLLHLRPTELANRTLSEGLHMILKELTD
                     KSDIEVIYKETIAQLPKTMEDNLFRIAQEFISNTLKHAKASRIEVYLNQTSTELQLKM
                     IDDGVGFDMDQVRDLSYGLKNIEDRVNDLAGNLHLISQKGKGVSMDIRLPIVKGDDDE
                     "
     gene            131294..131935
                     /locus_tag="VCR92_000133"
     CDS             131294..131935
                     /locus_tag="VCR92_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP4267232.1"
                     /translation="MSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDL
                     ALALKPDVLVMDLVMPELGGVEATLEVLKKWKEAKVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN"
     gene            131972..133372
                     /locus_tag="VCR92_000134"
     CDS             131972..133372
                     /locus_tag="VCR92_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEP4267233.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKDTGYMPESIQRVFKALKA
                     KGILVGIASGRARYGVPQEVQDLHADYCVKLNGAYVKDDAKTIIFQAPIPADVVVAYK
                     KWADDMGIFYGMAGRHEAVLSARNDMISNAIDNVYAQLEVCPDYNEYHDVYQMWTFED
                     KGDGLQLPAELAEHLRLVRWHDNSSDVVLKGTSKALGVSKVVDHLGLKPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPLLQEKADFITKKVKEDGILYALEELGLIDKELQFPQL
                     DLPNHKGPKATIKTNHGDMTLVLFPDHAPKTVANFLGLAKEGYYDGIIFHRIIPEFMI
                     QGGDPTGTGMGGQSIYGESFEDEFSDELYNLRGALSMANAGPNTNGSQFFIVQNSKIP
                     YAKKELERGGWPAPIAASYAAIGGTPHLDRRHTVFGQLVDETSFQVLDLIAGVETGAQ
                     DKPKEDVIIETIEVFD"
     gene            133372..133749
                     /locus_tag="VCR92_000135"
     CDS             133372..133749
                     /locus_tag="VCR92_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEP4267234.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDDI
                     DQLLAIGNQVLVQVIDIDEYSKKPSLSMRTLAEEKQHFFHRHRYSNSRHKIGFRPLEE
                     QLPQWIEESLQFLKKNTKKSLEP"
     gene            complement(133767..134708)
                     /gene="cysK"
                     /locus_tag="VCR92_000136"
     CDS             complement(133767..134708)
                     /gene="cysK"
                     /locus_tag="VCR92_000136"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEP4267235.1"
                     /translation="MTKIYKTITELVGQTPIIKLNCLIPNEAADVYVKLEAFNPGSSV
                     KDRIALSMIEAAEAEGLISPGDVIIEPTSGNTGIGLAWVGAAKGYRVIIVMPETMSLE
                     RRQIIQAYGAELVLTPGAEGMKGAIAKAETLAIELGAWMPMQFNNPANPSIHEKTTAQ
                     EILEAFKEISLDAFVSGVGTGGTLSGVSHVLKKASPETVIYAVEAEESAVLSGQEPGP
                     HKIQGISAGFIPNTLDTKAYDQIIRVKSKDALETARLTGAKEGFLVGISSGAALYAAI
                     EVAKQLGKGKHVLTILPDNGERYLSTELYDVPVIKTK"
     gene            complement(134836..135468)
                     /locus_tag="VCR92_000137"
     CDS             complement(134836..135468)
                     /locus_tag="VCR92_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEP4267236.1"
                     /translation="MEHFKTIKASGFFEESIKKSRFICHIKRVSTEEDGKNFVNAIKK
                     EHYKANHSCFAMIIGNNSQIKRSSDDGEPSGTAGIPILSVLEKQCLTNVVVVVTRYFG
                     GIKLGTGGLIRAYSNMTATAIKRFGIIEVKQQIGLEITLSYPQYQLYSNLLDQLALTE
                     TETKFSDTIKTTLYCDTERVENLIDTLTNYYHGQISCEKIGSKVIEFPCD"
     gene            135524..136849
                     /locus_tag="VCR92_000138"
     CDS             135524..136849
                     /locus_tag="VCR92_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEP4267237.1"
                     /translation="MESIENSYGRLLLESQLPDSAKQLAQPLKSVVISRGKMICQRCH
                     YQLDEEARLPNGAYYCRFCLVFGRNQSDKLLYAIPPMHFPKGNYLVWSGQLTAYQEMI
                     SQQLLINMQNQKTTLVHAVTGAGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATR
                     LSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQL
                     HYAASQALKEGGAKILLTATSTRTLERKVNKGEVVKLTLARRFNNRPLVIPKFIRSFN
                     LFKMIHRQKLPPKILKYLKKQRKTGYPLLIFLPTIIMAESVTAILKELLPAEQIACVS
                     SQSQNRKEDITAFRQGKKTILITTTILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAG
                     RVGRSIDRPDGTLYFFHEGISKAMLLARKEIKEMNYKGYSHDLSTMSTN"
     gene            136821..137486
                     /locus_tag="VCR92_000139"
     CDS             136821..137486
                     /locus_tag="VCR92_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEP4267238.1"
                     /translation="MICLLCQQISQTPISITEIIFLRRISSPICQQCQKSFQKIGKSV
                     CATCCANSDIIACRDCLKWENKGYNVNHRSLYCYNAAMKAYFSQYKFQGDYLLRKVFA
                     VELADVITKYYKGYIPVPVPVSPGCFRERQFNQVSAILEAANVSYLSLFEKLDNTHQS
                     SRTKKERLLVEKSYRLLKVSNIPDKILIVDDIYTTGSTIIALRKQLAKVANSDIKSLS
                     IAR"
     gene            137566..138114
                     /gene="raiA"
                     /locus_tag="VCR92_000140"
     CDS             137566..138114
                     /gene="raiA"
                     /locus_tag="VCR92_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEP4267239.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFAKDQEIDARVNL
                     KVYRERSSKVEVTIPLDSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KVPTGQVFTTEFEAEEVDEIPEVQVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDS
                     EDGATNILYRREDGNLGLIEAK"
BASE COUNT        42848 a        24561 c        29580 g        41754 t
ORIGIN      
        1 gctttagcat ttcatttatt tactggtcaa gcatactatg gaatagtcat agatcggatg
       61 attaaacaac tgccttttta tattgctatt attgctttgt gtcaattttt gtttaatata
      121 cttcgtaaaa cttatcagtc aatcacagct tatatacttt atgtccttct ttttgataaa
      181 gtatctgcta ctttagcaaa ccattttttt aagttagata ttagcccagt tttgatgttt
      241 aaacacctat ccttgtctct tggtgataaa cacctttcta gtactagcat attagtggcc
      301 tttggtttaa ctctttgtta tcttttaggc aatgtctttc ttttttccaa acgagaacta
      361 aaataaaggg taatatgtgc tttgtttatt ttaaaagaca aagaagttct tagaaaaagg
      421 tcgtcttcat cattactaaa aaaggataag caagtagttt tgttattatt caagtaagct
      481 catacttaat gagacaaaat aaagacttgt ttacccggta tctgattgct aagagttgga
      541 tttattggaa tactggtctc aaactgttat agaaatgatt atgagtgcac aatctcatag
      601 tttgaaacat agttgtttat tctagacatt taggagatgt cctaatttaa agcttaaagt
      661 actagaaatg tcccactaat atgttttagt gggacatttc taaaggaagc tagattatcc
      721 ttcaatataa tcttttagct cttgaccagt aagtccggcg ttgagagcaa ttaataactt
      781 tagacgggct tttggagcat tcaattcttt tacaaacata acacctgctt cttgtagcat
      841 cgcaccacca ccttcataag catagacagg ttctgccata ccattgaaac aacgggaaac
      901 aagaacgaca ggaataccta aagtaattaa gtgctcgatc tccccaactg ctaatggtgg
      961 gacatttcct gcccctagag cttcgataac tagaccttga atgctacctg gagttaatag
     1021 actcaagata ctaccatcgc ccatacctgc gtatgctttg ataatgggga tggttccaga
     1081 aatgcatctc aagtcaaaac gaatacgagg ttcagcagtt ttgaaaaaaa gtaggtcatt
     1141 tttcatgatg ataccaagcg gtccgtgtgt gggtgtttgg aaagttgaaa tattggttgt
     1201 atgtgtttta gtaacatatt tagcagcatg gatttcatcg ttcataacaa caagtacccc
     1261 tttttcttta gctttatcac tacttgcaac tctaagtgcg gtaaggtaat tatatatgcc
     1321 atcactacca acttcattag aagacctcat agcacctgtt aggacaacag gtatattagt
     1381 aggcaatgcc atggtatcta aaaaataagc tgtttcttct aaggtatctg ttccatgtgt
     1441 gatgactata ccatcaaaga catcagttct ttcttgaata tgatgataaa tagataacat
     1501 gtggtgaggc gtgatgtgag gactcggaag atttagaaaa tcactaacgg taagctgaat
     1561 atcttgggct gcagcatgta ttttcgtcat aggattatct tgatttggaa caaccctacc
     1621 agagttatca gcttgcatag aaatggttcc accagtgtgt aagactagga tttttttcat
     1681 ttgattgtca aacttccttt tatttatgat ataatctatt ctatcataaa cacaggaggc
     1741 aaaagaaggt tttgacagta aaagcagtct tttttgatat tgatgggacc cttctcaatg
     1801 atcgtaaaaa tatccaaaaa acaacgcaaa aagccatcca acaactcaaa aaacaaggca
     1861 ttatggtcgg tttagcaact ggtcgtggac cgggatttgt acaacctttt ctagaaaatt
     1921 ttggattaga ttttgccgtt acttacaatg ggcaatatat cttaacaaga gataaggtct
     1981 tatatcagaa tcaattgcca aagtcgatga tttacaaagt gattcgctat gccaacgaaa
     2041 aaaagcgaga aatttctctt ggaacagctt ctggattagc aggatcgcgt attattgata
     2101 tggggactag cccatttgga caagtcatta gtagttttgt gcccaaaagt tgggcaagaa
     2161 cagttgaggg tagttttaag catttgattc gccgaatcaa gcctcagagt tttagaaatt
     2221 tagtaactat tatgcgggag cctatttatc aggttgttct ggtagcgtca caagctgaaa
     2281 ctaagaaaat acaagagaag ttccctcata taaaaattac aagaagtagt ccttattcct
     2341 tggatctgat ctctgttgat caatcaaaaa taaaaggaat tgaacgtttg ggagagatgt
     2401 ttggatttga cttgtctgaa gtgatggctt ttggagattc agataatgac cttgaaatgt
     2461 tatcaggagt tggtatcggt attgctatgg gaaatgctga aactgtggta aaagatggag
     2521 cccatttcac taccgactct aataataatg atgggatttc caaagcctta gctcactacg
     2581 gtctcatcca ttttgatata gagaagagct ttaaaagccg tgatgaaaat tttaataaag
     2641 tcaaagattt tcatcgtctg atggactcag atactattga aacaccgcgt agttatacca
     2701 tttcagaagc tggttatagg tcaggcttta aagtagaaga aattgttgag tttctttacg
     2761 cagcaagcaa gggagaccaa caacaattta cacaggctat tttcgatttg catggtgctg
     2821 ttgaccaagc agctaataag gtacaagcta aaaaacatgt tgaaacgccc ctgattgggc
     2881 aagttgatgc cttagcggat ttgctttatt ttacttatgg ttcttttgta ctgatgggag
     2941 tagatccaca acctatattt gaagcagtac atgaagcaaa tatggctaaa atttttccag
     3001 atggcaaggc acactttgac cccgttaccc ataaaattca aaaacctgac tattggcaag
     3061 agcgtcacgc acctgaagta gccataaaaa aagagttaga caaacaatta caaaaatcac
     3121 tacaacgatt cgataaatag aggtttactc ttttaaatat caagaaataa aaagatattg
     3181 actagactta gctcagcaca aaaaaacaag caatttcgtt gtagatgctg cttgtttttt
     3241 ggtgtttgaa aattgtaata gactagagtg ttttagtgct atctcggact acaagtaagt
     3301 caatcttagc gtgtcgcata atgtactcag aagatgagcc aataaggagg cgttcaaagg
     3361 tattaagacc agtagctcct accataatta aatcagcgtt ctcacgatct ggaatatcgt
     3421 gagctagtaa gtttttgggg ttgccaaatt caataatttg tttgatgttt gtaattcctg
     3481 ctatctgtgc ttgtttttca aaatcatcta aaacatcctt agcttcttgt tctaattttt
     3541 catagatgta agtatcaaaa gtagctacgc tttgcaaggc acgggtatca ataacgtgta
     3601 ctagtagtaa ggtagcgtcg ttacgtagtg ctacgttaac gcctttattg aaagctaatt
     3661 cagactcata agagccatca atagcaacga ggatacgttt atattttagt gacatagaac
     3721 tgtcctcctt taacagtttg acaagaatag cttttattct ttttttcatt atactctttt
     3781 ttgagtcatt ttgaaagcga tccattattt ttgctaaact aaagactgta ttatcgtctc
     3841 ataagacctg tgttaaaacg attagctgtc ctaagctttg atggataaat tctttctatt
     3901 ttaagtattt tggtttataa tatggaatac gaggtgtatg agactatgaa aattattgaa
     3961 aaatcatcaa aattagaaca tgttgcctat gatattcgag ggcctgtttt ggatgaagct
     4021 aatcgcatga ttgcgagtgg tgaaaaaatt ctgcgtttaa atactggcaa tcctgctgct
     4081 tttggttttg aagcaccaga tgaagtgatt cgtgatttaa ttgtcaacgc gaggctaagt
     4141 gagggctatt ctgacagtaa agggattttt tcagcgcgta aggctatcat gcagtattgc
     4201 caactcaagg gcttcccaga tgttgacatt gaagatattt atttgggaaa tggcgtgtca
     4261 gagttgatat ccatatccct tcaagctttg ctagataatg gcgatgaagt tttagtacca
     4321 atgccggatt atcctttatg gacggcttgt gtgagtcttg gtggaggaaa agcggtccat
     4381 tatctttgtg atgaagaagc tggttggtat cctgatattg ctgatatcaa atcaaaaatc
     4441 acgagtcgca ccaaagctat tgtggtcatc aatcctaata acccaacagg agccctttat
     4501 cctaaggaga ttttagaaga catcgttgct ttggcaagag aacaccagct gattattttt
     4561 gccgatgaaa tctatgatcg tttggtgatg gatggtaaag agcatattgc tattgcaagt
     4621 ttggcacctg atgttttttg tgtatctatg aatggtcttt ccaaatctca tcgtattgct
     4681 ggttttcgtg ttggatggat ggtcttatca ggtcctaaag accatgttaa aggttacatt
     4741 gaagggttaa acatgcttgc caatatgcgg ttatgctcca atgttttagc ccaacaagtt
     4801 gttcaaactt ccttaggagg tcatcaatca gttgatgcac tgttactgcc aggagggcgt
     4861 atttttgagc aacgtaattt tatttatgaa gctattaatg ctatccctgg cttatcggca
     4921 gttaaacctg aagcaggtct ttatttattt ccgaaaattg atcgtcagat gtatcgtatt
     4981 gatgatgatg aagaatttgt cttacagtta ttaaagcaag aaaaagtgat gttggtacat
     5041 ggacgtggtt ttaactggaa agatccagat cacttccgta ttgtttacct accaagtgta
     5101 gaagaattag aagatgtcca agaaaagatt acacgtgtct tataccagta tagacgttaa
     5161 tgcaatgctc atctttgatt aataaaaata gcgtttctta aaagaatgtg atcctatgct
     5221 ctaacaagct agtgcttatc tcctttaaat gaagtgataa taaggcatca atagttggaa
     5281 ttgtagtaag aatagaaaat tttctgataa ttccttgcaa aagcgagtta gctttgttat
     5341 aatgaaagcg caaataattc aaaggaaaag gaaaaaaatg cctaacttat tagaaaaaac
     5401 tcgtaaaatc acatctattt tgcagcgttc cgtagatagc ctagaaacag aattaccgta
     5461 taacacaatg gcatctcgcc tagcagatat cattgactgc aatgcttgta ttatcaatgg
     5521 cggcggcaca ctgcttggtt atgccatgaa atataaaact aacactgatc gtgttgagga
     5581 attttttgaa gctaaacaat ttccagatac ttatgtaaag gctgctagcc gagtttacga
     5641 tacagaagct aacctttctg tcgaaaatga attgactata ttccctgttg agtctaaaga
     5701 cacttatcca ggaggtctaa cgactattgc gccgatttat ggtggaggga tgcgccttgg
     5761 atcactcatt atctggcgta atgacaatga gtttagtgat gatgatttga ttttggttga
     5821 gatctcaagt actgttgtgg ggattcaact attaaatctt cagacagaaa acttagaaga
     5881 caccatccgt aaacaaacag cggtcaacat ggcaattaat acgctttctt attcagaaat
     5941 gaaagctgtt gcagcaattc ttggagagtt agatggtaac gaaggacgat tgacagcttc
     6001 tattattgct gatcgtattg gtattacccg ttctgttatt gtcaatgctc tgcgtaaatt
     6061 agaaagtgca gggattattg aaagtcgttc tcttggtatg aaagggacat acctcaaagt
     6121 tatcaacgaa ggtatttttg ctaaattaaa agaattttaa atagaaaaag acaacatctc
     6181 ttgaaaagag atgttttttg ctgttaatgg tagatgcaaa tagatgtctt gatacctgta
     6241 ataaaaactg atacaatgcc atatataaga gataagggga gaggtttccc tgtttaggag
     6301 agagtgatga gagcattgat ttcaattgat tacacaaatg attttgtagc agatgatggt
     6361 aaattaagtg caggtaaatc tgctcaggct attgccacta aaatagcaga ggtaactaaa
     6421 acggcatttg atcaaggaga ctatattttt tttgctattg attgtcatga tcaaaatgat
     6481 ccttggcatc ctgagagtaa gttatttgca gcacataata tcaaaggaac tactggacgc
     6541 catctttatg gtccactagc tgaagtttac agttatatga agcaacatcc cagagttttt
     6601 tggattgata agcgttatta ttcagctttt tcggggactg atttagatat tagactacga
     6661 gaaagaggta tcactcaatt agtgttaaca ggagttttat ctgatatctg tgtcttacat
     6721 actgctattg acgcttatca tcttggttat caattagaga ttgttaaatc ggctgtcgct
     6781 agccttacaa aagaatctta tgagtggtct ttggctcact ttgagcaggt tcttggtgct
     6841 aagcttatta acgattacta aaagagccta ccaaactatt gattcagtga ctaagagttt
     6901 ggtaaccgta atcattgctc tatgtggttt taccgtatgt atgggttagg tagatgaggt
     6961 atgtgacatg ctggtcagaa ttagtcctga tgattcttgt gctgtctaaa aggcaactaa
     7021 actttggact gtgtcagata gaacacatgt ttttttgaag gagacaggat tttagctgtt
     7081 tgagaaatga tttgagttgg tggtttagag gatcgtctca cagccattag acaaactcta
     7141 gtcttttcag cattagaata taaataaagc ttcaaactct tgaatgctag agtctgtacc
     7201 atttttatct taggcttatc acatcacatg ttgtcacaat cgttgaggat ttggtaaatt
     7261 agaataaagc acccctttac taccttcgta aacatattac cgacttgaaa gaacgttact
     7321 ttttctgtga tgttgtagga aaatacttgg aagaatacgt tgacaggggt atttttgata
     7381 aggagccgtt ccagaccttt gatcagaaag ggattggccg tctctttagc ccgttcggtt
     7441 aagcctgagt tgaaacttgg tatttgtggg gaacatggtg gcgatcctgc ttccattgac
     7501 ttttaccaca gccaaggcct gacctacgtt tcttgttcgc catttagagt gccgcttact
     7561 cgcttggcgg ctgctcaggc tgccatcaaa gcttcaggcc acagtcttac ccaagacaaa
     7621 tagagtttag tttgtcacac ttcctgacta aggttttctg accttagtca ggaagttttt
     7681 tgctgtatag ctttctagaa ttgcattagt cacctatggt aaatgggcgc aattgtgata
     7741 taataattga gactatgtaa aaacgatgtg aggagttttt ccgctacctt tggagaatag
     7801 cagagctgtt ctttggaatt ggaatacttc tgatcatctt ggatgggaga aatcatgaaa
     7861 atttctgaag aagaagttcg ccatgtcgcg aagctatcaa aattatcatt cttagaaagt
     7921 gagacaacaa cctttgcaac gaccttatcc aaaatcgttg atatggttga attgctgaac
     7981 gaagttgaca ccgaaggtgt cgccattaca acaaccatgg cagataagaa aaatgtgatg
     8041 cgtcaagata ttgctgagga aggaacagac cgtgccttgc tctttaaaaa tgttcctgaa
     8101 aaagaaaatc actttatcaa ggtacctgct attttggatg acggaggaga tgcctaatgt
     8161 cttttaatca taaaaccatt gaagagttgc atgacctcct tgtagctaag gagatttccg
     8221 caaccgaatt gactcaaaaa acacttgaag acatcaagtc tcgtgaggag gctgtcgggt
     8281 cgtttatcac tgtttcagaa gaagctgctc ttaaacaagc tgcggcaatt gatgccaaag
     8341 gtattgatgc tgataacctc atgtcgggta ttccactagc tgttaaggat aatatctcaa
     8401 ccaagggcat cctaaccaca gccgcttcaa aaatgttgta taactacgag ccgatttttg
     8461 atgccacatc agtagcaaat gcctacgcta aagacatgat tgtcattgga aaaaccaaca
     8521 tggacgaatt tgccatgggt ggttcaacag aaacctctta tttcaagaaa acgaaaaatg
     8581 cttgggacca cacaaaagta cctggtggct catcaggtgg ttcggcaaca gcagtcgctt
     8641 caggacaagt ccgtttatct cttggttcag acactggtgg ttctattcgg cagccagctg
     8701 catttaatgg tgttgtcggt ttgaaaccaa cctatggcac tgtttctcgc tatggtctca
     8761 ttgcttttgg aagttcactt gatcagattg gaccttttgc tccgacagtt aaagaaaacg
     8821 cccaattatt aaatgtgatt gcaagtagcg atgtcaagga tgccacttca gcgcctgtcc
     8881 gcattgcaga ctacacatct aagattggtc gtgacattaa aggcatgaag attgcccttc
     8941 ctaaagagta tcttggcgaa gggattgatc ctgagattaa ggaaacggtt cttgcggcag
     9001 ctaaacaatt tgaagcctta ggagctactg ttgaggaagt tagtcttcca catagcaaat
     9061 atggtgtggc tgtctattac attattgctt cgtcagaagc gtcctcaaac ttacaacgtt
     9121 ttgatggcat tcgctatggt ttccgtgctg acgatgctaa aaacttggat gaaatctatg
     9181 ttaacactcg tagccaaggc tttggtgatg aggttaaacg tcgtatcatg cttgggacct
     9241 ttagtttgtc atcaggttat tatgacgctt atttcaaaaa ggccggtcaa gtgcgtacct
     9301 tgattattga agattttgac aaggtctttg cggattatga tcttatttta ggcccaacaa
     9361 caccgacggt tgcttttggc ttagacacac tcaaccacga tcctgttgcc atgtatttgg
     9421 ccgacttatt gaccattcca gttaacttgg ctggtctgcc aggaatttcc attccagcag
     9481 gattcgtcga tggcttgcca gtagggcttc aattaattgg tccgaaatac gctgaagaaa
     9541 ccatctatca ggcggcagca gcctttgaag cggtgacaga ttatcacaag caacaaccga
     9601 ttatttttgg aggtgacaag taatgaattt tgaaaccatt attgggcttg aagtccatgt
     9661 ggaattaaat accaattcca aaattttctc accttcgtca gctcactttg gtgaggaccc
     9721 aaatgccaac acgaatgtga ttgattggtc tttcccaggg gtcttaccag tcatgaacaa
     9781 aggggtgatt gatgcgggca taaaagctgc gcttgccctc aatatggaca tccataaaga
     9841 gatgcatttc gaccgcaaaa attatttcta cccagacaat cctaaagctt accaaatttc
     9901 acagtttgac gagccgattg gctacaacgg atggattgag attaaattgg aagacggctc
     9961 gactaagaaa attcgtattg aacgcgcaca cttggaagaa gatgctggta aaaacactca
    10021 tggcacagat ggttattctt atgtggacct taaccgccaa ggagttcctt tgattgagat
    10081 tgtgtcagaa gccgacatgc gttctcctga agaagcctat gcttatttga cagctctgaa
    10141 agaaatcatc cagtatacgg gtatttctga tgtcaagatg gaagaaggct ccatgcgtgt
    10201 ggatgccaat atttctcttc gtccttacgg gcaagaacaa tttggaacaa agaccgaatt
    10261 gaaaaacttg aactccttct caaatgtccg taaagggctt gaatttgagg tggaacgtca
    10321 agccaaactc ttgcgttcag gtggtgtgat acgccaagaa acgcgccgct atgacgaagc
    10381 gaataagggg actattttga tgcgggtcaa agaaggggca gcggactatc gttatttccc
    10441 agaaccagac ctgccattat atgagattga tgatgcttgg attgacgaga tgcgtgctca
    10501 attacctcaa ttcccagctc agcgtcgtgc taaatacgaa gaggaacttg gcctctcagc
    10561 ttatgatgct agccaactaa cagctaccaa agccttgtca gatttctttg aaactgcagt
    10621 aagtcttggt ggcgatgcca agcaagtctc taactggttg caaggggaag ttgcccaatt
    10681 cttaaatgca gaaggcaaaa ccattgaaga aattagattg acgcctgaca acttagtgga
    10741 aatgattgct attattgctg atggtacaat ctcttctaaa atggctaaga aggtctttgt
    10801 gcatttggct aaaaacggtg gctcagctcg cgcctacgtc gaaaaggcag gacttgttca
    10861 gatttctgat cccgctgttt tggtaccaat tattcaccaa gtctttgctg ataatgaagc
    10921 tgcagtggct gatttcaaat caggcaaacg taatgctgat aaggctttca caggcttctt
    10981 gatgaaggca accaaaggtc aagctaatcc acaagtcgct caacaattat tggcacaaga
    11041 attgcaaaaa ttgcgagatt gatagttgct gatagcaata agttaaagta ttttgtctct
    11101 gaaaaaaagg cggtcggtct ttcacaggct gcctttttgt atgtcatgtt agtgaccgtc
    11161 tataaaaaga ccatcatcta tgctaaaata agactgacag gtattgcttt agaaccttca
    11221 ggagtttctg acgtgtattt aatgaactat cacgtttgtc tacactatta ttagcgatta
    11281 gctgtgtgat aaagtttgtt aagttattta gtgtgtgaag acttctagtc gttctcggtc
    11341 tatctacctt aatagaagga attgtttttt ctattttact caggcacgga aacatttact
    11401 aaagaagaag gtaaaggaat caactaaagt taagaacatt taatggatag cagttcttct
    11461 aaaaggattt tacaagaaag gaggtgttaa cgatgatatg gtctttaatt gtaggtgcct
    11521 ttatcggcat gatagcaggt aaaatgactg aaaaaagcca gtccatgggt tgttttacta
    11581 atattatcgc aggtctcata gggtcagctg ttgggcaaag gctttttggg gattggggaa
    11641 ttcagttggc aggtatggct attttcccgt ccattttggg agcggcaatt gtaattgtac
    11701 ttgtttcagc tatttttgga aaaaggtatt aaaaaaaggc tgcatggaag tttccaagca
    11761 gccttttttg caacataaaa tgtcttatct ttttattggt tgcatcctca ttataagata
    11821 gttgtgtgaa aatttaatat cattttcttg acaaatagtt agattttgtt actgttttga
    11881 catcattttg taatgtcagt ttagttgtag tgtgggtctg ttgttatata tatttgagcg
    11941 aaacgcacaa atgtaatcgt ttggaaattt atgtgatgat ttgaattgta gcaatagcat
    12001 tatttttaat aaaatagaca ataagtcagt ggtctatttg atctcaaata gctatcagga
    12061 agtgttttgc aagtgttttc tttaaatgct ataataatta ataagacagt ttaggaggtt
    12121 gaaatgacaa aaacaaggtt gtatattgcc agacatggaa aaacgatgtt taataccatt
    12181 ggtcgcgctc agggttggag tgacacacct cttacaaaaa aaggagaaga aggtattcga
    12241 gaacttggct taggtttaaa agatgcaact ataccattta aggctgcgtt ttcaagtgat
    12301 tcaggtcgaa ccatgcagac aatagaaatt attttaagag aatcagaaaa cgaatttttg
    12361 ccttatacta aagataatcg tattcgtgag tggtgttttg ggagtctaga agggacttat
    12421 gattcagaat tatttctagg tgtccttcca agaacaaaag cctttgaaaa tcgtgataac
    12481 ctacgtgatg ttccctattc tgaactggca gaaagcatcg tggaagtaga taccgctaat
    12541 tgggcagaac catgggaagt tcttcgtaag cgcatttggg aggggtttga agctattgct
    12601 ttgtctattc aaaatgctgg cggcggaaat gctcttgtgg ttagccatgg gatgactatt
    12661 ggaacattta tgtggctaat cgatcctgac cgtgagaaac aatatattga taacggcagt
    12721 gtcactgttg tcgaatttga agatgggcaa tttaccatca aaaccattgg agatatgagt
    12781 tatcgctacc gtggccgtga aataatagaa gcaatgtcag atgaagcata atcattttaa
    12841 attattattg caaacactgg ttgttctgct ctttgtcgga ggtatttacc tctttattaa
    12901 gccagagaag caggccacca agacgccttc aagtcaacag gcaagcagtc aaaaagtggt
    12961 caaaaatagc aaagagtcca cagggcttcc taaagtctct ccaaaagatt gggaattgat
    13021 tttagtgaat cgggaccata tgactgagga attgagccca gaattagttg acattaatgg
    13081 tatttctgtg gataaacgca ttgagcaagc cactagtgat tttttagcgg cagctcaggc
    13141 tattgaccca caagagcacc ttatttcagg ctatcgctcc gtagcttacc aagcagagct
    13201 ttaccaatct tatattaaaa aagagatggc taacgatcca acattgacac aagaagctgc
    13261 ggaggctttg gtgcaaacct atttacagcc gccaggggct agtgaacatc acactggtct
    13321 tgctattgac atgagcactg tagatacttt aaatgccagt gacccatcgg tatctaaagc
    13381 agttcaaaaa attgcacctg attatgggtt tgtcttgcgc tttccagaag gaaaaaagac
    13441 tagtacaggg gttgattatg aggattggca ttaccgctat gtaggcaagg cgtctgctcg
    13501 ttatatggct cagcacaacc taacgttgga agagtacatt gctgctttaa aggagaaacg
    13561 atgagaaaac gactaaagtt tccgtatttt ttaacgcttc tagcttgctt tttattgctg
    13621 attgtttgtc ccttactgag tagccaaagg atagctagtg cagataaaga agtaagggtg
    13681 aactacagcc aaaaacaatt tattacaaaa atgggtaaag aagttaaacc attggcaaaa
    13741 tattatggca ttagaccatc tattttgatt gctcaaattc ttttggaaac ccatgatgga
    13801 aaaacattac tagcgtctaa gtatcataat ctttttagca agaaagcaac tccaggacaa
    13861 gcggccatta ccctaaagtc ccctaaacaa accaaccaaa acgtgagata tgctatttat
    13921 aaagatgacg ctagtgcaat tagagattat ttacgaatgc ttcggcaggg aaaagaagtc
    13981 gataagcgtt tgtatcgtaa tcttgctaca gaaaaagggt ataaagcacc agctaaaagt
    14041 ttacaaaagt atttgcatta tactgataaa acctatgcta ggcgactgat tcaggtcatt
    14101 gaaagtaacg atttaacaaa ctatgactga aattagcact ctttataaaa gagtgctaat
    14161 ttttttgagt ttttttcttg acatgtgtcc cataaagagt ataatagaat tataaattag
    14221 cagtctacta aatagagtgc taaacgaaag ggagtggttg gtttgtgatt acacaacgtc
    14281 aaaatgatat tttgaattta atcgttgagc tatttacaca aactcatgaa ccagtagggt
    14341 ctaaagcttt acagagaacg attgattcta gtagcgccac tattcgtaat gatatggcaa
    14401 aactagagaa gttgggattg ttggaaaaag cgcacacttc tagtggacgg atgccaagtc
    14461 cagctggctt taagtatttt gtagagcact ccctcaggct agatagtatt gatgagcaag
    14521 atatttatca tgtcataaaa acttttgatt ttgaagcatt caaattagaa gacatgcttc
    14581 aaaaagctag tcacatttta gcggagatga cgggctatac atccgttatt ttagatgtgg
    14641 agccagctcg tcaacgttta acagggtttg atgttgttca gcttagcaac catgatgctc
    14701 tagcagtcat gactttagat gaatctaagc cagtgacagt gcagtttgct attccaagaa
    14761 actttttgac acgtgacttg atagcattta aagctatcgt agaggagcgc ttgctggata
    14821 gtagtgtcat agatattcat tataagttga ggacagaaat tcctcagatc gttcaaaagt
    14881 attttgtgac tacggataat gttttacaac tatttgatta tgttttttca gagctgtttt
    14941 tggaaacggt atttgttgct ggtaaggtaa attctttaac gtattcagat ctatcaacgt
    15001 atcagttttt ggataatgaa cagcaagtag caatttcttt gaggcaaagt ctgaaagaag
    15061 gtgagatggc ttctgtccaa gtggcagata gtcaagaagc cgcacttgca gatgtgtcag
    15121 ttttgactca caaatttttg attccttacc gtgggtttgg actcctgagt ttgattggtc
    15181 ctattgatat ggattatcgt aggtctgtta gtttggtaaa cattattgga aaggtattgg
    15241 ctgctaaatt aggtgattat tatcgatacc taaattctaa ccattatgaa gtccactgat
    15301 aatggcagta ttcaataagt tatttaaaag gaggcactca gtgtcagaag aaattaaaaa
    15361 agacgattta caagaagaag tggaagccac tgaaactgaa gagacagttg aggaagttat
    15421 tgaagaaact cctgaaaaat cagagttaga acttgcaaac gaacgtgctg atgagtttga
    15481 aaataaatac ttgcgagctc atgcagaaat gcagaatata cagcgtcgct ctagtgaaga
    15541 acgtcaacaa cttcaacgct atcgttctca ggatctggca aaagcaatct taccatcgct
    15601 tgacaatcta gaacgtgcct tggctgttga agggttgaca gatgatgtta aaaaaggttt
    15661 agaaatgact cgtgatagcc ttattcaagc actaaaggaa gaaggcgtag aagaagtaga
    15721 agttgactca tttgaccaca actttcatat ggcagttcag accctcccag ccgatgatga
    15781 acatccagcc gatagcattg cagaagtctt tcaaaaggga tataaattgc acgagcgtct
    15841 gctaagacca gcgatggtag ttgtctataa ctaaggtaaa tgagttttcg tttttgtccg
    15901 taatgacagt aaactagata gcaagttaga agttatttcg cttgctgatt aaactatagt
    15961 gattgcttag aattggaagt aaaataattc gagtgcttac taagataaat tgaaataaaa
    16021 agtaataaag tattataaaa taagaggtat taacatgtct aaaattattg gtattgactt
    16081 aggtacaaca aactcagcag tagcagttct tgaagggact gaatcaaaaa tcattgctaa
    16141 cccagaaggc aatcgtacaa ctccttcagt agtatcattc aaaaatggtg aaattatcgt
    16201 gggtgatgct gcaaaacgtc aagcagtgac aaacccagaa acagtaatct ctattaaatc
    16261 taaaatggga acttctgaaa aagtttctgc aaatggtaaa gaatatactc ctcaagaaat
    16321 ttcagcaatg attcttcaat accttaaagg ttatgctgaa gactatcttg gagaaaaagt
    16381 agaaaaagca gttattactg ttccagctta cttcaacgat gcacaacgtc aggcaactaa
    16441 agacgctggt aaaattgcag gtcttgaagt agaacgtatc gttaacgaac caacagcagc
    16501 cgcacttgct tatggtatgg acaagactga caaggatgaa aaaatcttag tttttgacct
    16561 tggtggtggt acatttgacg tatcaatcct tgaattaggt gatggtgtct tcgacgttct
    16621 tgcaacagca ggtgataaca aacttggtgg tgacgacttt gaccaaaaaa ttattgattt
    16681 cttagtggct gaatttaaga aagaaaatgg cattgactta tcacaagata agatggcact
    16741 tcaacgcttg aaagatgctg ctgaaaaagc taaaaaagat ctttcaggtg tgacacaaac
    16801 acaaatttca ttaccgttca tcactgctgg ttctgccggt cctcttcact tggagatgag
    16861 cttatctcgt gctaaatttg acgatctcac tcgcgacctt gtagaacgta cgaaaactcc
    16921 agttcgtcaa gccctttcag atgcaggatt gtcattgtca gaaattgatg aagttatcct
    16981 tgttggtgga tcaactcgta tcccagcagt tgtcgaagct gtaaaagctg aaactggtaa
    17041 agaaccaaat aaatctgtaa accctgatga agtggttgct atgggtgctg ctatccaagg
    17101 tggtgttatc actggggatg tgaaagacgt tgtccttctt gacgtaacac cattgtcact
    17161 tggtattgaa acaatgggtg gtgtcttcac caaattgatc gaccgcaaca ccactatccc
    17221 aacatctaaa tcacaagtct tctcaacagc agcagacaac caaccagctg ttgatatcca
    17281 tgttcttcaa ggtgaacgcc caatggcagc agataacaag actcttggtc gcttccaatt
    17341 gactgatatc ccagctgcac ctcgtggaat cccacaaatt gaagtaacat ttgatatcga
    17401 taaaaacggt attgtttctg taaaagctaa agaccttggt acgcaaaagg aacaacacat
    17461 cgttatcaaa tcaaacgacg gactttctga agaagaaatt gatcgcatga tgaaagacgc
    17521 tgaagctaat gccgaagccg atgcgaaacg taaagaagaa gttgacctta aaaacgaagt
    17581 tgaccaagct atctttgcta ctgaaaaaac aatcaaagaa actgaaggta aaggctttga
    17641 tacagaacgc gatgcagcgc aatcagctct tgacgagtta aaagctgcgc aagaatctgg
    17701 caaccttgac gacatgaaag ctaaacttga agcattaaat gaaaaagcgc aagctttggc
    17761 tgttaaaatg tacgagcaag ctgtagcagc tcaacaagca gcacaaggtg cagaaggtgc
    17821 acaagctaat gattcagcaa ataatgatga tgttgtagat ggcgaattta cagaaaagta
    17881 atgatttagt tatctagtaa cattaatatc cgaattcaga ggttgtacca aacctctgtt
    17941 tttggctaaa taaaatgtaa aaatgctgac gtcaaaatat tttaagaaag gaatacaagt
    18001 tcgattattc gaacacaggc taaagcgtgt aaagactctt ttgcggattc gaacacgcct
    18061 acgactctgc gaaaaaagag aaatacctcc tagatacgag agtatctttg tcggatttcc
    18121 tatttttcat tgagtcgttt tacggcttgg tatcttacat tatgaacaat acagaatatt
    18181 acgatcgtct gggggtttct aaggacgctt ctcaggacga tatcaaaaaa gcttatcgaa
    18241 aaatgtctaa gaaatatcat ccagatatca ataaagaagc tggagcggag caaaagtata
    18301 aggatgttca agaagcttac gaaaccttaa gtgattcaca aaagcgtgct gcttatgatc
    18361 aatacggcgc tgcaggtgct caaggcggct ttggtggcgg agcaggcggc tttggtggtt
    18421 ttgacggagg tggctttggt ggttttgaag atatcttctc aagcttcttt ggtggcggtg
    18481 gaagccgaaa cccaaatgcc cctcgtcaag gtgacgattt gcaatatcgt gttaatttat
    18541 cttttgaaga ggctgtattt ggtgttgaaa aagaagttag ctataatcgc gaagcaacct
    18601 gcggcacttg tttaggctca ggtgcaaaac ctggtaccgc tccagtaact tgtcgtaagt
    18661 gccatggttc aggtgtaatg acaattgaca cccaaacacc acttggtatg atgcgtcgac
    18721 aagtcacctg cgatatttgt catggtagtg gtaaggaaat taaagaaccc tgtcaaacct
    18781 gtcacggtac tggtcatgaa aagcaagctc ataaagtgtc tgttaagatt ccagctggtg
    18841 tagagactgg tcagcaaatc cgtttacaag gtcaaggaga agctggcttt aatggcggac
    18901 cttatggtga tttatttgtt attttgaatg tcttaccaag taagcaattt gaacgcaatg
    18961 gttccactat ttactacaac ttagatattt cttttactca agcagcctta ggagatactg
    19021 ttgaaattcc aacggttcat ggcgatgttg agatggctat ccctgctggg acacaaacag
    19081 gtaaaacctt ccgcctcaaa ggcaaaggag caccaaaact ccgtggtgga ggtcaagggg
    19141 atcaacatgt taccgttaat attgtgaccc caaccaaact caatgacgct caaagggaag
    19201 ccttgcaagc atttgcagaa gcgagtggtg aaaaaatgtt acatccaaag aaaaaaggtt
    19261 tttttgataa agtgaaagat gccttagagg atatttaaag atgtcaaacg tataatctca
    19321 ggataatttt cccgaagtta tacgtttttt tacgtcaaaa cagttagaga aaacgttttc
    19381 ttttatagat atcgtttttt tctcttgtca aaatggttta tttagtatat cataattagg
    19441 taattgattt gattatcaaa tgattttaaa gagaaataat ttcttagtca aataaattat
    19501 cagaaaagag gattgttatg cagtttaaac acatcatctt tgatgttgta gatgatcttg
    19561 cgacattgac tttaaaccgt ccagaggttt caaacggttt taatattcca atttgtcaag
    19621 agattctggt agcattagca gaagttaaac gcgatacatc tgtgcgtttt ttattaatta
    19681 aagccgttgg aaaagtgttt tcagttggtg gtgacctagt tgaaatgcaa gaagctgttg
    19741 caaaagataa tgtgcagtcg ctagtcaaga ttgctgaact ggtacaagaa atttcttttg
    19801 caatcaagca tttgccaaaa ccagtcatcc tttgcgccga tggagctgta gctggagcgg
    19861 cttttaatat agctttagct gttgactttt gtatcgctag tactcaaaca aaatttatcc
    19921 aagcttttgt aaatgttgga ctagcaccgg atgccggtgg tttatttcta ttgactcgtg
    19981 cagtaggact taatcgtgca actcaccttg tgatgacagg tgaaggaatt actgctgata
    20041 aaggtctcga ttatgggttt gtctaccgta cggcagaatc tgataaacta gacaaagttt
    20101 gtcttcaact tttaaagcga ttgagacgtg gctcttcaaa ttcttatgct ggaatgaaat
    20161 cattggtctg gcaaagcttt ttcacaggat gggaagatta tgctaaggca gagcttgcta
    20221 ttcaagagga gctagctttc aaggaagatt ttaaagaagg tgtcatagct tttggagaaa
    20281 ggcgccgacc aaattttcaa ggtaagtaag acagctgttg cttgcaaaat actttgacct
    20341 ttgatataat ttgattgtca aagtttattg ctaggaggtg tttacttgga atatgacaaa
    20401 attaaccaat acttagttga tattttcaac cggattttgg ttattgaaga aatgagctta
    20461 aagacgagtc agtttaatga tgtctcttta aaagagatgc acactattga aattatcggc
    20521 aaatatgatc aggtgactcc aagtgatatc gccagagaat taatggtaac gttagggaca
    20581 gtaacgacta gcttaaataa attagaagca aaaggttata tcgcaagaac gcgatcacgc
    20641 tcagataggc gagttgttta cctgtcatta acaaaaaggg gtcgactttt ggaccgcctc
    20701 catgcaaagt tccataaaaa tatggttgga catgtcattg ctgatatgag tgatgaagag
    20761 atgcaggcat tggtgcgtgg actagggaat ctacatcaat ttttggagga tttggtttaa
    20821 atgatttttt ctaaaatcag tcaggtagcc cactatgttc cacagcagtt agtgactaat
    20881 aatgatttag ctagcataat ggacactagt catgagtgga tcttttctcg aacaggaata
    20941 gcagaacgcc atatttctag agatgaaatg actagtgacc tagctattca ggttgctgat
    21001 cagcttttaa ctcagtctgg gttaaaagct gatgctattg attttattat tgttgcaact
    21061 atcagccctg atgccactat gccatcaaca gctgcgaaag ttcaagcagc tattgcggct
    21121 acaagtgctt ttgcttttga tatgactgct gcttgtagtg gctttgtctt tgccttggct
    21181 atggcagata agcttattgc atcaggtgca taccaaaacg gaatggtaat aggtgcagag
    21241 actttatcta agttagtaaa ctggcaggat cgagcgacag ccgttctttt tggagacgga
    21301 gctggtggcg tgctactgga agccagtaaa gataaacatg ttttagcgga aacattacac
    21361 acagatggtg cgagatgtca gagtttaatt tcaggagaaa ctagtctttc atctccgtac
    21421 tcaattggca aaaaagccat agcgactatt cagatggatg gacgtgccat atttgatttt
    21481 gcgattaggg atgtgtcaaa aagcatcctc acactaatgg cgcaatcaga tattacaaaa
    21541 gatgacatag actattgttt attgcatcaa gctaatcgtc gtatacttga taaaatagca
    21601 cgcaagattg atgttcctcg ggaaaaattc cttgaaaaca tgatgcgtta tggtaatact
    21661 agtgctgcta gtatcccaat tctcttgtca gaggctgttc aaaagggaca gattaggtta
    21721 gatggtaccc aaaaaatctt actttccggt tttggtggag gtttgacatg gggaagtcta
    21781 attgttaaaa tctagttatt catgtgccta gcacatttat aaaaacaaat ttatattttt
    21841 taaggagaaa taaacatggc agtatttgaa aaagtacaag aaattattgt tgaagaactt
    21901 ggtaaggaga cagaagaagt aacgctagaa actacatttg atgatttaga tgcagattca
    21961 cttgatgttt tccaagttat ttcagaaatt gaagatgctt ttgatattca aattgaaaca
    22021 gaagaaggat taaatactgt tggtgacctt gttgcttacg ttgaggaaaa gtcaaaataa
    22081 ggataaaagt gacaagtaac atcagaagtc tatgaaaagc ttactgctgt tatgttcatg
    22141 ttcatcacta aaaaaaacaa taagtattaa tcaaaccatt agggtgggat tagactcttt
    22201 ttaggatcta gctcgctctt tcttcttact ataatagttt gattatcaaa ttattctcct
    22261 tattttttat agaaagttat tatgaaaaca cgtattacag aattacttaa tattgattac
    22321 cccatttttc aaggaggaat ggcttgggtt gctgatggtg atttagcagg tgcagtttct
    22381 aatgctggtg gtttaggcat tataggtggt ggcaatgctc ccaaagaagt cgttaaagct
    22441 aatattgatc gtgtcaaagc tattactgat agaccttttg gggttaatat catgctttta
    22501 tctccttttg ctgatgatat cgttgatctg gtcattgaag aaggtgttaa agtagtaaca
    22561 acaggcgcag gaaatccagg aaagtatatg gaaagactgc accaggcggg tataatcgtt
    22621 gttcctgttg tcccaagcgt tgcgctagcc aaacgtatgg aaaagcttgg ggtagatgca
    22681 gtgattgctg agggtatgga agctggagga catattggca agttaacgac tatgtcttta
    22741 gtaagacaag ttgttgaagc ggtttcgatt cctgtcattg cggcaggtgg tatagctgat
    22801 ggtcatggtg cagcagcagc atttatgtta ggagcagagg ctgttcaaat tggaactcgc
    22861 tttgttgttg ctaaagaatc caatgcccac caaaatttta aagataaaat cttagcagca
    22921 aaagatattg atacggtgat ttctgcgcag gttgtgggcc accctgtccg ctctattaaa
    22981 aataaattga cctcagctta cgctaaagca gaaaaagcat ttttaattgg tcaaaaaaca
    23041 gctactgata ttgaagaaat gggagcagga tcgcttcgac atgctgttat tgaaggcgat
    23101 gtagtcaatg gatctgttat ggctggccaa attgcagggc ttgtgagaaa agaagaaagc
    23161 tgtgaaacga ttttaaaaga tatttattat ggtgcagctc gtgttattca aaatgaagct
    23221 aagcgctggc aatctgtttc aatagaaaag tagataaaca catgaaggat aatgataatg
    23281 acaaagacag cctttttatt tgccggtcaa ggtgcccaaa aattagggat ggcaagggat
    23341 ttttatgata actttgctat tgtaagaaaa acctttgatc aagctagtca agtattggga
    23401 tacgatttgc gccgtttgat tgatagtgac gagttaaaac ttaatcaaac tagctatacg
    23461 caaccagcta ttttgacatc atcaattgct atttaccgtg ttctgggctt acatcacgtt
    23521 aaaccggata tggtagctgg tctttcctta ggagagtact cagctttggt agcatcaggg
    23581 gcactctctt ttgaagatac cctatcctta gtagctaaga gaggccgctt gatggaggaa
    23641 gcagcaccac aaggatctgg aaagatggtt gccgttatga atacagacgt gcaagtcatc
    23701 gaagaagtct gtcaaatagc tgctaaacat ggagtggttg ctccagcaaa ctataatact
    23761 cctagtcaaa ttgtaattgg tggtcagaca gatgctgtga acgtggcagt tgaactttta
    23821 aaggaaaggg gagttaagcg tttaatccct ttaaacgtgt caggtccttt ccacactgct
    23881 ttgttagaac cagctagccg cttgttggct aaagagttgg aaagatacaa cttcagtgac
    23941 ttcaagattc ctttggttgg taataccgaa gctaatatta tggaaaaaga tcgtatccca
    24001 gaactattag cccgtcaagt catggagcct gttcgttttt atgacagtgt tgcgacttta
    24061 gtagaaagtg gcataacaca attcattgag gtaggaccag gtaaggtttt gacaggtttt
    24121 gtgaagaaaa ttgataaaaa tttactatgt actagtgttg aaaacatggt aagcttacgt
    24181 ttatttttag atagagagga tattcatgga aattaaagga aaaaatatat ttatcacagg
    24241 ctcaacgaga ggtatcggtt tagcaatggc tcatcaattc gccagtttag gagctaatat
    24301 tgtcttaaat ggtcgctctg ctatctctga ggagcttgtt gctagtttta ctgactatgg
    24361 tgttacagtt gttaccatct ctggggatgt ttcagaagca tcagaagcta aacgtatggt
    24421 caatgaagct atcgaaagtt taggttcgat tgatgtttta gttaacaatg ctggcattac
    24481 taatgataaa ttgatgctta aaatgacgga agaggatttt gagcgcgtct tgaaaatcaa
    24541 tttgaccggt gcttttaaca tgactcaatc agtgttaaaa ccaatgatca aggcccgcca
    24601 aggagcaatt attaatgtct ctagtgtggt tggtttaaca ggcaatattg ggcaagcaaa
    24661 ctatgctgct tctaaggcag gaatgattgg ttttaccaag tctgttgccc gtgaagttgc
    24721 tgctcgtaac atttgcgtga atgctattgc tccaggattt atcgagtccg acatgacagg
    24781 tgtccttcct gaaaaaatgc aagagcaaat cttaagtcaa atcccaatga aacgtattgg
    24841 aaaagctcaa gaagttgctc acttagcaag cttcttggtg gaacaagatt atattacggg
    24901 acaagttatc gctattgatg gcggtatgac aatgcaataa ggagacgtag tgaaatgaca
    24961 tttaaaagag tagtggtaac aggttatggt ctaacatctc caatcgggca tgatcctgaa
    25021 acgttttgga acaatctgaa agctggccaa attggtattg gtcctattac taaatttgac
    25081 acgactgatt atgcagtcaa gaatgctgct gaaattcagg attttccatt tgacaaatac
    25141 tttgtgaaaa aagatttgaa ccgtttcgat agatattctc tttatgctct ttacgcagcg
    25201 aaagaggcta ttaatcatgc tgatttaaat attgagatgg ttgattccga tcgatttggc
    25261 gttattgttg cttcaggtat tggtggaatt gcggagattg aagagcaggt gattcgctta
    25321 catgaaaaag ggccaaaacg tgtgaagcca atgacgttgc caaaagcgct accaaatatg
    25381 gctgcaggaa atgtcgccat gtctttaaaa gctcaaggag tatgtaaatc aattaatact
    25441 gcctgcgctt cttcaaatga tgcgattggg gatgcctttc gtgccattaa atttgggact
    25501 caagatgtga tgatagttgg tgggtcagag gcggccataa ccaagtttgc cattgctggc
    25561 ttccaaagtt taacagctct ctcaacaact gaagatccaa gcagaagctc tattccattt
    25621 gataaagacc gaaatggttt tatcatggga gaaggatcag gaatgcttgt tttagaaagc
    25681 ctagaacatg cgcaagaacg cggggcgaca atcttagcag aaattgtggg ttatggaaat
    25741 acctgcgatg cctaccatat gacatctcca aatcctgagg gattaggagc tcgtaaagcc
    25801 atccacttag ccttacaaga agctggtatt gaagccagtg ctattaatta tgtcaatgcg
    25861 cacggaactt caactccagc taatgaaaaa ggagagagtc aagcaattgt agccgttctt
    25921 ggtaaggatg ttccggtgtc ttcaacaaaa tcgtttacgg gtcaccttct tggagcagca
    25981 ggcgctattg aagctattgc cactatcgag gctatgcgtc ataactatgt tccgatgacg
    26041 gctgggacac aagctttatc agaggatatc gaagcaaatg tcatctttgg agaaggaaaa
    26101 gaaacagcta tcaactatgc catttcaaat acttttggat ttggtggtca taatgctgta
    26161 ttagctttca aatgttggga ggagtaggtt gaatattcaa gaaatcaaag atttgatggc
    26221 tcagtttgat acctcaagcc tacgtgaatt tttattcaaa acaaatgaag gtgagctaat
    26281 ctttagtaaa aacgaacaac acctcaatgc atcgacatca aatcaagaac atgctgtgcc
    26341 tgtaccacag gtacaacttg ttccgaattc aactgcttcg gaagcgtcca gtccagcatc
    26401 agttaaggat gttcctgtag aggagcaacc acaagcagaa tcttttgtag cagaaggtga
    26461 tattgttgaa agtcctttag tcggtgtagc ctatcttgca gctagccctg acaagccacc
    26521 atttgtggca gtcggagata ctgtaaaaaa aggacaaacc cttgtgatta tcgaagccat
    26581 gaaggtgatg aacgaagtgc cagcgccatg tgatggtgtg attacagaaa ttttggtatc
    26641 aaatgaagat gtcattgaat ttggacaagg attggtgcgg atcaaatgat ggatattaga
    26701 gaaattcaag cggctttgcc tcatcgctac ccaatgttat tggttgatcg tgtgttagaa
    26761 gtgtcggacg accatatcgt tgccattaaa aatgtgacta ttaatgaacc tttctttaac
    26821 gggcattttc ctcactatcc tgtgatgcca ggtgttctga ttatggaagc tttggctcaa
    26881 acagctggtg tcttagaatt gtcaaaagaa gaaaataaag gcaagttggt cttttacgct
    26941 ggaatggata aagtgaagtt caaaaaacaa gtcgtccctg gtgatcaact tgtgatgaca
    27001 gcaaccttta tcaagcgtcg cggtaccatt gctgtcgttg aagccagggc agaagttgat
    27061 ggcaagctag cagcaagtgg aacattaacc tttgcctgtg ggcaatgaga atgattgttc
    27121 tgcggaggaa gaaaccctta tgtttaaaaa aatcttaatt gctaatcgtg gtgaaattgc
    27181 agtgcgtatc attcgtgctg cacgagaatt agggatttcc acagttgcag tttattcgga
    27241 agcggataag gaagctctgc acacgatatt ggcggacgag gctatctgta ttggtcctgc
    27301 ccgttccaag gaatcctatc ttaatatgaa ttccgtcttg tcagcagcta ttgtgacagg
    27361 agcccaagcg attcacccag ggtttggctt tttaagtgaa aactcaaagt ttgcgaccat
    27421 gtgtgaagag atgaatatta aatttatcgg tccatccgca tcggttatgg ataaaatggg
    27481 tgataaaatc aatgctcgtt ctgaaatgat taaggcagga gtgcccgtta ttccagggtc
    27541 agatggtgaa gtttataacg ctcaagaagc cttagctatt gccaataaga ttggttatcc
    27601 tgtcatgcta aaagcatcgg caggtggtgg aggtaaaggg attcgtaaag tggagacaga
    27661 agcagatttg gaggcggctt tcaatgctgc cagtcaagaa gctttgggag ctttcggaaa
    27721 tggcgccatg tatttggaaa aagtaattta cccagctaga catattgagg tgcaaatttt
    27781 aggagacgct cacggtaaca tcattcactt gggagaacgg gattgctcct tgcaacggaa
    27841 taatcaaaaa gtcttggaag aaagtccatc cattgctatt ggcaataccc tcagacacga
    27901 aatggggcaa gcagcggtta gagcagctga agctgtagcc tatgaaaatg cgggaaccat
    27961 tgagtttttg ttggacgaag acagcgagaa attctatttc atggaaatga atacccgtat
    28021 ccaagttgag catcctgtca ccgaatttgt gacaggagtg gatattgtca aagagcaaat
    28081 caaaattgca gcaggtcagc ctttggcgat tagtcaagaa gacatcacta tcacgggaca
    28141 tgctattgaa tgtcgtatca atgctgaaaa tactgctttt aactttgcac cgagtccagg
    28201 aaagattaca gacttgtata tgccaagtgg tggtgtagga ctacgagttg attcagcagt
    28261 ttacaatggc tatgccattc ctccttatta tgacagcatg attgctaaaa tcatcgttca
    28321 tggaagcaat cgatttgacg ctttgatgaa aatgcaacgt gccttagttg aattggaaat
    28381 tgaaggcatt atcaccaata cagacttcca gctcgatttg atttcagata agcgagtgat
    28441 tgcaggagat tatgatacct ctttcttgat ggaaacgttc ctgccacatt acaataaaga
    28501 ttaggagaaa atatggcttt atttcgtaaa aaagataaat acatccgtat tactcccaat
    28561 aattccctca aaggatctgt cagccataat gtcccagaag ttccagatga actctttgcg
    28621 aaatgcccag cttgtaagca catgatttat aagaaagatt tgggattggc aaagatttgc
    28681 ccaacctgtt cttacaattt taggatttct gcccaagagc ggctgacctt aacagttgat
    28741 gaaggctctt tccaggaatt atttacaagt attgaaacca aggatccgtt acgctttcca
    28801 ggttatcagg aaaaattaca aaaagccaag gaaacaactg gtctgcatga agctgttttg
    28861 acagggaaag ctatggttaa aggacaacaa attgctcttg ctattatgga ttctcacttt
    28921 attatggcta gtatgggaac tgttgttggg gaaaaaatta cccgattgtt tgaattggct
    28981 atcgaagaaa acctgccggt ggtgattttt acggcttcag gaggcgcccg tatgcaagag
    29041 gggatcatga gccttatgca aatggccaag gtctctgcag ctgtgaaaag acattctaat
    29101 gcaggcctct tttacctcac tattttgaca gatccaacta ctggtggggt aacagctagt
    29161 tttgccatgg aaggggatat tattttggca gaacctcaat ccttggttgg ctttgcaggt
    29221 cgtcgtgtca ttgagaccac agttcgtgaa aacttgccag atgatttcca aaaagcagaa
    29281 tttttacaag accatggttt tgtggatgct attgtgaaac gaacagagtt gcgagacaag
    29341 attgcccact tagtagcatt tcatggaggt ggccaatgac agatgtatca agaattttaa
    29401 aagaagcgcg tgatcaaggg cgtttaacaa ctttggatta cgccaacctt attttcgatg
    29461 actttatgga actgcatggc gatcgccatt tttcagatga tggtgctatt gtaggtggct
    29521 tagcttattt ggcgggacaa cctgttacgg tcattggtat tcaaaaaggt aagaatttac
    29581 aggataattt ggcaaggaat tttggccagc ccaatccaga aggttatcgt aaagctttgc
    29641 gccttatgaa acaggcagaa aaatttggac gaccagttgt tacgtttatc aatactgcag
    29701 gagcctatcc aggtgtcggt gcggaagaac gaggacaggg tgaggccatt gctaaaaatt
    29761 tgatggaaat gagtgatctc aaggttccca ttatcgccat cattattggt gaaggaggct
    29821 ctggtggtgc attagcctta gcggttgccg atcaggtctg gatgctagaa aacaccatgt
    29881 atgcagtcct tagtccagaa ggctttgctt ctattttatg gaaagatggt tcaagagcga
    29941 cagaggctgc tgaattgatg aaaattaccg caggcgaatt gtatcaaatg ggcatagtag
    30001 accgtattat tccagaacat ggttattttt caagtgaaat cgttgacatc atcaaagcta
    30061 acctcatcga acaaataacc agtttgcaag ctaagccatt agaccaatta ttagatgagc
    30121 gttaccaacg ctttcgtaaa tattaacaac atccttttgg agtctcccta cgtgtttatc
    30181 aagctaaggg aggcctttcc aaaagggttt ttaactagtc ttgtaaataa ggaaatgggt
    30241 atactaataa gacttttgat aaactagtgt gaaaaaaagt gttgttaaag gggcaatgta
    30301 gtgagtttca agtgatgtgg tggctcttta aaatagtaaa ccccagaaat cactttaatg
    30361 atctctgggg tgagtttatt atttaggtga aatgacggtt tcgccaccca tgtaagagcg
    30421 gagtacttca gggatggtaa cagaaccatc ttcattttgg tagttttcta aaatggctgc
    30481 tacggtacga ccgacagcaa gtcctgaccc attaagggtg tgaagaagtt tgaccttacc
    30541 gtcagcttca tcacggtaac ggatttgagc acgtcgtgct tggaaatctt cagtatttga
    30601 acatgatgaa atttcacggt aggtgttttg tgcaggaatc cagacttcaa ggtcataggt
    30661 tttagcagct gagaagccca tgtctccagt acaaagggaa atgacgcgat atggcaaacc
    30721 aagtttttga agaatatttt cagcattagc agtcattttt tctagttctt ggtaagattc
    30781 ttctggttta gcaaatttaa ccatttcaac tttgtggaat tggtgtaggc ggataaggcc
    30841 acgtgtgtca cgacccgcag aacccgcttc agaacgaaaa gatgggctca ttgcagtaaa
    30901 gtaaattggc aattctttgc cgtctaggat ttccccacgg taataattgg tcaaaggcac
    30961 ttcagcagtt ggaatcagga caaagttggt atctgctaat tcaaaggtgt cctctttgaa
    31021 ctttggatat tgtcctgtac caaacatgga atcgtggtta accatgtaag gtgtgatgat
    31081 ttcttgataa ccttctttga tatgttcatc cagcatgaag ttataaagag cacgctccaa
    31141 acgagcacca agatttttat agaataagaa acgagcacca gttacctttg ccccacgttc
    31201 ccagtctaaa atatcaagat cttcgcctag atcccaatga gccttaactt cgaagtcaaa
    31261 gtcacgaggc gttccccaac ggcgaatttc gacattgtct tcttcgtcag ctccaacagg
    31321 gacagaatcg tgaggagtat taggtaaaac agtgatgatg tcagtaactt gctggtcgat
    31381 agctactagt tgattgtcaa tagttttgat atctgcagag actttttgca tatcagcaat
    31441 ttgttgagtg gcatcttctt tttgacgttt tgcttgggcg atggctgcag aagcaatatt
    31501 acgctctgct tttaattctt ctgattgcac taatagagca cgacgttttt catcaagttc
    31561 tttaagatgg gtcagggtgt cttcagaaac accgcggttt tttaatttgg cagcgacagt
    31621 gtcaaaatcg gtacggatac gtttaagatc tagcatacag aagctccttt aagatagtta
    31681 ttagtagctg tcagtgaaac aaggctaagt aagacagttg gatcttgtga ttctctgacg
    31741 atagaaaaag cacagcttat gaagatgctg gagcgctttg gcgcggttcc atccagcttc
    31801 acaatctgtg cacttaatct ctattttatt gatgacacgg tagaatttca tatcattttc
    31861 cctatctgtt cacagcatcc acagactctc tgaatgaaaa aaaggtatta cttatccgtt
    31921 aggactatta taacaaaaaa caagaaaaag taaactcaaa tgagggaatc ttttccacta
    31981 aatagcaatt tagagctact attctttgct ttcttgaaat gataaatcag cactgctcat
    32041 tattttttta atgtcgaaaa aatttgttaa taaaggtttg catcaaggtt ggtaatgtaa
    32101 tcactttctc attaccaata tgttgacgag tgatttttaa gatttttcca gagtctccag
    32161 aagcaaataa aaacttgcct tggtccgtaa aaatttcaaa gtggcggcta actttttttc
    32221 ttgaaacatt agccccgatg tgattgatag ctgtccaagg aatttgaata taatcattca
    32281 catttttatc gttgtaaaat tcaagggcct tgtcaccgag taaaatatga ccaactttgc
    32341 ctcctattcc aaggtaggag acagcttttg tcttgtattc gacactagtg tttaaagatt
    32401 gagccattta agttcctttc attgcgtagt tgtagttatt ataccatatt ttaagtggga
    32461 ttttcctgac ataaagcata aaaaagaagc ctgagttcat ctcagacttc cattggttga
    32521 ttacataata cctgcaaggt gagcaaggat accaaatgca aacaagccga tgatgattgc
    32581 gattggagaa acttttttct tcaataacca catgcaaagg aatgtaagga gtaatccagc
    32641 taaacctggg ataagagagt ccaattgtcc ttgaagggtt tgagcttgga ctttatcaag
    32701 gctcataccg ccaatagcgt tggcaaggat agttttcaac tcagcacctt taacagcgcc
    32761 atctgggaag accacatagg caccatctga caattgtttt ccaggaaggt cgatagtaaa
    32821 gttgatagat acccaacgtt gaacaagcac tgcaaggata aacattccaa ggattgaagc
    32881 acctttagta atgtcttgga ggataccgcc tgacatgtct ttagtaattt cagaaccagc
    32941 tttgtaacca aattcttgag tataccataa gaaggccata cggataaggt tccatccaaa
    33001 gaagaacaga agtggaccaa cgatgttacc tgttgaagcc aaagaagcac caagtgcccc
    33061 aaggatagga cgaaccgtaa accagaatac tgggtcaccg ataccagcaa gaggtcccat
    33121 cataccgatt ttaacccctt ggatagcctt gtcatcaatt ggcgtaccat ttgcgcgttc
    33181 ttcttcaagg gcaagtgtta caccaatgat tggagctgca acgtatgggt gagtgttaaa
    33241 gaattccatg tggcgctcaa gagcagctgc acggtcttca ggagacgtat acaatttttt
    33301 aagagcaggg ataagtgcat aagcccagcc catgttttgc atacgttcgt agttccaaga
    33361 accttgtaag aattgtgaac gccaccaaac acgttgacgg tctgatttag ttaatttaat
    33421 ttgttcagtc atttgttctt acccctttct agtagtcttc taagatgtcg ccgattggat
    33481 cagctgaacc tgctgcatta ccaccgttac cacctttttt agaaagatta aggtagatga
    33541 aggcaattgc tacaccgata acacccatag cgataagggt taattggctg atagctgcaa
    33601 gagcaaaacc tagggcgaag aatggccata cttcacgagt agccatcatg ttgataacca
    33661 tagcataacc tacagcaaca accatcgcac caccgatttg cataccttcg ttcaaccagt
    33721 ttggcatagc attcaaaaca gattgtacgg ctgaagtagg aacagcaaca agaagagctg
    33781 ctgggacagc gatacgcaat ccttgaagaa gaagggcaat aaagtggaag cgttcaatac
    33841 ctgcgaaatt accttcagtg gcagctttgt caccagcgtg tacaagggca gttgacaaag
    33901 tacgaacgat cattgtaagg aaaagaccag caacagcaag tgggatagct gttgagtaag
    33961 caaaggtaat tcctttttga gtaaagtcgc cacttttgac catgatgata gcagctgcaa
    34021 cagaggcaag ggcagcatca ggggcaacgg cagcaccgat gtttgcccaa ccaagagcaa
    34081 gcatttgaag tgtaccacca aggatgacac cagcttcaag gtgtccagtt acaagtccaa
    34141 tcaaagtaca ggcaacaagt ggttggtgca tttgaaattg gtcgaggata ccttcaagac
    34201 cagcgaagaa ggcaatgata acgactaaaa ttgcagaaat aatcgaaata tctgacatgt
    34261 tgtaatcctt tcaaagtata gtaaacgagg actttttgct aataagttag ctagtcatcg
    34321 ttttaaaacc ttatagcgtt tgaaacttat ttaatgttag ctttttggat aagctcaaat
    34381 aagtttttct tagaatcgtt aggaacttta cggacgtcga atgtaacacc taggtcgcgt
    34441 aatttttcaa aagtagcaac gtcttctttg tccattgata aaacgttgtt aaccattgtt
    34501 ttaccagttg agtgagccat tgaaccaacg ttcaattcgt tgatttcaac accaccttca
    34561 accgcgcgaa gggcatcttg aggggtttgg aaaagaataa gtgcgtgtgt gttaccaaaa
    34621 cgaggatctt tagaagcttc aatcaatttg ctaattggaa caacgttagc tttgacacca
    34681 ccaggtgcag cctgtttgat caattgtttg cgaaggtcat cttgagcaac ctcatcagaa
    34741 gcaacaatga tacggtcagc cttagaagct ggagtccatg ctgttgcaac ttgaccgtgt
    34801 aaaagacgag tgtcaacacg agcaagattg atctttaatt taccatctcc gatgacagtt
    34861 ccagcaggaa tagctccttg aagtgcgtta acaacttttt cagttgcagc agtttcttca
    34921 actgggttaa ggtcttcagg aagggctttg ataccgtcct tagattcctt aatgatgttt
    34981 gcagcaactt gttcaacacc tgcaccagca tccataagac gttcagtgta agcttgaata
    35041 agcataggca agttgagacc agtgatgatc gccattttgc ggtcaggatt ttcacctgcc
    35101 acacgactag cttggttaaa tggagaacca ctccaaaggt cagctagcac aaggatttca
    35161 tcatcagcat caaattgttg gatagcattg ttgaagtgtc catacaaatc atctggtcct
    35221 tcgtttggca tgaaagtaac aacttgaact ttctcttgtt caccaaaaat catagaacca
    35281 gattgatgaa taccttcagc aaatttacca tggctggcaa taataatacc gatacccatt
    35341 cttgttcttc ctcctttaaa atatttttcg ttgaaatgaa gaagaataat ctccttccaa
    35401 aactaaattt tggcaattct ttttcactta aacgaaattc aagaacgttt ctattttaaa
    35461 acgttttcac taaaaaatca agccctttcg gaaaaatagt acaaaacatg aaaaaatttt
    35521 cagaatttag gattaaatag gcagattatt gatattaaag gtgttttcaa gctgtttaaa
    35581 acaaaaatat gctgaaaaat gttgaaatta ttaaaatgat tttcattttt tgatagctgt
    35641 tgacagaaga aaaaccacca ttttctgaaa aatagtggtt tcgtttgcta ctacaagaaa
    35701 agttcttcca attttttggc aacaccgtct tcttcgttgg aaaaattaag ctgctgatca
    35761 gcataaggca gtagcacagg gctagcattt ttcatagcat aaccagttcc agcaaaagct
    35821 agcatctcag tgtcattgtg ttcatcacca aaggcgatta aatccttttt atccatattg
    35881 taaattccaa ggagatagtt cagagcgtaa gctttattga cattcttaga cgaaatttca
    35941 agaatgttga gagggcctcc ccaagaatca atttcaattt catctttgaa gaaagcacgc
    36001 atgtttttag ctaaggcata cttgtcttcg tgatgcgttt gcatcaataa ggcgtttgga
    36061 tttcgagtga ttttggtaat ctctaatgcc atgtcctgag taatttcatc aacaccaaag
    36121 agttgagggt cgatactttc tggattggtc atggtgatgt agacattttt tcgatactca
    36181 ctggcaataa aatccatctg gaaatcatcc tgatatttta gtaaccttag taggtagcct
    36241 ttgtccaaag tgacattatg ttcataggcc catttttgtt caggcatgtg ggtcaaggcc
    36301 ccattaaaag taatgattgg ggtctttaaa ttgagctgca gatagtagtc cagtgccatg
    36361 cggtaaggac ggcctgttga aataatgacg tggtggccct tgtcttggac agctttgatg
    36421 attttttgag tataggtaga gatggtgttg tcatgatgta ataaggttcc atccaaatca
    36481 atggcaatca attttttagt cataattaaa ttatagcaaa ttttgctcca agataaagag
    36541 aaaagataag ttaagcgtat tcattagtaa aaaagatagg ataactgttt ttttaatgaa
    36601 taaatgaagt tacagacgtt gaaaagtgaa caaaaaaatg gtaacatagt gttattgttc
    36661 attttaatac gaacaataac aataataatg aggtgtcaaa aagacttatc tagtgataag
    36721 cgctttttga ttttacctac tatttaatta aggagactcc atttcaatgg aaaagttttt
    36781 taagttaagc gaaaatggga caactgtctc aactgagatt atggctggtt taacgacctt
    36841 ttttgccatg tcctatattt tgtttgttaa cccaagtatt ttaggtgcag cggggatgcc
    36901 ctctaatgct gtctttttgg ctacgattat cgcagcagcc atatcaacct taattatggg
    36961 actatttgcc aatgtgcctt atgcgttggc accaggaatg ggacttaacg cttttttcac
    37021 ttatacagtt gtttttgctt tagggttttc atggcaagaa gccttggcaa tggttttcat
    37081 ttgtggatta ttcaatattt ttattaccgt aaccaagttt cgtaaaagta tcatcaaggc
    37141 gattccagtt agtttacagc atgctattgg tgggggaatt ggtgtctttg tagcttattt
    37201 aggatttaaa aacgcaaata tcattacttt ttctatctct gctgaaaata tagtaatggt
    37261 aaatggtgtt gaaccggcta aagcatcggc taaaacattt gcagatggtc tattatttgt
    37321 agacgccaat ggtggagttg tacctacgat ttctagtttt acggattcta gtgtattact
    37381 tgctattttt ggtttacttt taacgacagc tcttgtgatt cgaaatttta gaggtgctat
    37441 tttaattggt attgtcgcaa caactcttgt aggtattcct ttaggaatag tggatgtgtc
    37501 caacctcaat tttgggatca gccatattgg tgaagcttgg actgaattag gtacaacttt
    37561 ccttgcagct ttcgatggtt tgagttctct ttttagcgat tcaagtcgtt taccgctagt
    37621 tttcatgact atttttgctt ttagtctatc agatactttt gacacaattg gtacctttat
    37681 cggaactggt cgtcgaacag gtattttctc tcaagacgat gagaatgctt tggaaaatag
    37741 tataggcttt agttcaaaaa tggatcgtgc gctttttgca gatgctatcg gtacttctat
    37801 tggggctttg gttggaactt caaatacgac tacctatgtt gaatcagcag caggaattgc
    37861 tgaaggtgga cgtactggac taacagcagt ctccaccgca gtatgcttct tattatcaat
    37921 attgctatta ccgcttgtag gtattgtccc agctgctgct acggctccag ctttaattgt
    37981 tgtgggtgtc atgatggtgt cttcttttct tgatgttaat tggagtaaat ttgcagatgc
    38041 tcttccagct ttttttgcag ctttctttat ggcgctgtgt tactctattt cctatggtat
    38101 tgccgctgcc tttattttct attgtctagt aaaagttgtt gagggaaaaa caaaagatat
    38161 tcaccctatt atttggggag caaccttctt gttcattgta aatttcatca tattaactat
    38221 cttataacca aataatttac ttattttgct actaactgcc gcttctttaa ttgattttaa
    38281 cctttaatat aacgaagcgt ttttacttta cgaatacctt attggagtca tcttctaggt
    38341 agtgcttgga agtatgtttt ttttctgata taatgttgct atgttttata gtgaaaatga
    38401 atatactctt aaagcttacg gagaaaccct aggtacttat ttgtctattg gagatgtgat
    38461 tgtattgtct ggcgacttag gtgccggtaa aacaacattg gcaaaaggta ttgctaaagg
    38521 gatggggatt agtcaaatga tcaaaagccc aacttatact attgttagag aatatgaagg
    38581 acgtctacct ctttatcact tagatattta ccgtgttggt gatgatccag actctattga
    38641 tttagatgat tttctttttg gtaatggtgt taccgttatt gagtggggag aattattagg
    38701 agagggatta ttacaagact atttgcaaat aaccattact aaacgagata aaggtcgtca
    38761 actagacttg ttagcgcatg gtgagcgctc tcgtcagctt ctggagataa tgtcacatga
    38821 ttcagcaaag tctcgttatt gaagaaggcg tacctcaaga tgcaaaagct gtactttcct
    38881 tagtggcggc agctgccaaa gaaacagatt ttataacagg cgtagagact atattagagg
    38941 ctactcctca tgaattatca gactttttat caagaagtca aacctctttt attgattttt
    39001 gcctgctagc tagattagat gaaaaagtag tagggctttt aaatctttct ggggaagtat
    39061 tatcccaagg ccaagttgaa gcagatgtat ttatgttagt tgctaagact taccgtggtt
    39121 atggtatcgg tcaattattg ttagagattg ctcttgattg ggctgaagaa aacccttata
    39181 tcgaaagcct taagttggac gttcaagtaa gaaatactaa ggctatttac ctgtataaaa
    39241 agtatggttt tcgtattgaa agtatgcgaa aaaacgacat caaatcaaaa aatggagatg
    39301 acttagatgt ttatcatatg cgtaaatctg taagtcagta agtgaatcga tgaaaattgg
    39361 aaaaaaaata gttttaatgt tcacagctat tgtgttaaca actgtcttgg cattaggtgt
    39421 ctatctaact agtgcttata ccttctcaac aggagaatta tcaaagacct ttaaagattt
    39481 ttcgacatct tcaaagaaaa gtgatgccat taaacaaaca agagcttttt ctatcttgtt
    39541 gatgggtgtt gatacaggct cttcagagcg tgcctccaag tgggaaggaa acagtgattc
    39601 gatgattttg gttacggtta atccaaagac caagaaaaca actatgacta gtttagaacg
    39661 agatacctta accacgttat ctggacccaa aaataatgaa atgaatggtg ttgaagctaa
    39721 gcttaacgct gcttatgcag caggtggcgc tcagatggct attatgaccg tgcaagatct
    39781 tttgaatatc accattgata actatgttca aattaatatg caaggcctta ttgatcttgt
    39841 gaatgcagtt ggagggatta cagttacaaa tgagtttgat tttcctatct cgattgctga
    39901 aaacgaacct gaatatcaag ctactgttgc gcctggaaca cacaaaatta acggtgaaca
    39961 agctttggtt tatgctcgta tgcgttatga tgatcctgag ggagattatg gtcgacaaaa
    40021 gcgtcaacgt gaagtcattc aaaaggtatt gaaaaaaatc cttgctcttg atagcattag
    40081 ctcttatcgg aagattttat ctgctgtaag tagtaatatg caaacgaata tcgaaatctc
    40141 ttctcgcact atccctagtc tattaggtta tcgtgacgca cttagaacta ttaaaactta
    40201 tcaactaaaa ggagaagatg ccactttatc agatggtgga tcataccaaa ttgttacctc
    40261 taatcatttg ttagaaatcc aaaatcgtat ccgaacagaa ttaggacttc ataaggttag
    40321 tcaattaaaa acaaatgcta ctgtttatga aaatttgtat gggtcaacta agtctcagac
    40381 agtaaacaac aactatgact cttcaggcca ggctccatct tattctgata gtcatagctc
    40441 ttacgctaat tattcaagtg gagtagatac tggctcatct tatcagagtg ctagtacaga
    40501 ccaggactct actgcttcaa gccatacgcc aactacgccg tcttcttcat cagatgcttt
    40561 agcagctgat gagtctagct catcagggtc tggatcatta gttcctcctg ctaatatcaa
    40621 ccctcagacc taacgttctg agggttttta tgtttaaaat atccgatttt gaatataaaa
    40681 aagacaggta tcaaagatga tagctgtctg tgatttcaaa taaagtatat gagggagata
    40741 atactatctg gaatggttgt tagttaaaat gacggtttgg caagtaggtg attcactaga
    40801 aattagctca ctatcttctt gatatttggc catacgattt tggatttcag taaggtgtgc
    40861 ttgtgtctct tggttaaagt agcgccattt atgggccaag tcctgactaa tattttgaat
    40921 tacttttcct tgactgtgaa tgaggtcaag gtttgcttta atgttatcta aatcaagttg
    40981 ggcagcatct tttgcttgtc gactgatgga taacagctct tttatggtac aacgtttttg
    41041 atatgctttg taagcggtaa aagataataa tccgacggct atcacggttt taactttcat
    41101 gaactaacct cctgattgat ttgtcgggcg agcttttcca agacaggaaa gttaggctca
    41161 tgagtggtgt attgaattga gataccgtct ttttcattat aacgaggaac gagatgaaca
    41221 tgagcatgga aaacagtttg tcccgctaag gcttcgttat tgttaatgat attcatggca
    41281 gtagcgccag tagctaactg gatagcacga gcaattttag gaatacgagc aaagagatga
    41341 ctagctgtct cagcagtcat ctctagtaag ttacgaacat gttgcttagg aatgactaga
    41401 gtatgccctt ttgtagtttg tgagatatct aaaaaggcga ggacctgctc atcttcgtag
    41461 actttcgaag aggggatatc cccttgaatg atgctgcaaa aaatacaatt ttccatttta
    41521 tatcaccttc tctacttgaa tttgttataa tatattataa gtatatcaaa aactagaaag
    41581 aaattatatg ttaaacatta aaaatctaac aggaggatat cacaatatcc ctgttttaaa
    41641 cgatgtctca ttttctgtag ataatggaga gttagtcggt ttgatcgggc taaatggtgc
    41701 tggaaagtca acaactatca acgaaattat tggctttttg aagccttatc aaggaagtat
    41761 ttctattgat ggtttaactc tagcagaaaa tgcagttgcc taccgtcaaa aaataggttt
    41821 tatcccagaa actcctagtc tctatgaaga attgacctta tcagagcata tcaacaccgt
    41881 agctatggct tatgatatcg acttagaagt ggcacaaaaa cgagcacaac ctttcttgga
    41941 aatgtttcgt ttaactgaca aacttgaatg gtttcctgtc aatttttcta aagggatgaa
    42001 acaaaaagtc atgattattt gtgcctttgt cattgatcca agtctattta ttcttgatga
    42061 accattctta gggttagacc ctttagctat ttcagactta atccaaacgc tagaagtcga
    42121 aaaagcaaaa ggaaaatcta ttttgatgag tacacatgtt ttggactctg ctgaaagaat
    42181 gtgtgatcgc tttgtgattt tgcatcatgg acaagttcgt gcccaaggaa ctcttgctga
    42241 cttgcaagaa gcttttggtg accgttcagc gagcttaaat gatatctatc ttgcattaac
    42301 aaaagaggat taagtatgaa agcattattt ctgaaacgcc gtcaagactt tcaaaaacaa
    42361 caaaacaaat accttcgtta cgtcttaaat gatcactttg ttttggtgtt gatgttttta
    42421 ttaggctatg ctatggtgca gtatggtcag ctactaaacc attttccaac gaatcatcta
    42481 cctattcagg tttgtcttgg gatattgatc ccattattgc tcagtatggg atctatagca
    42541 acgtatctag aagaggcaga tcagcatttc ttacttccaa aagaagaaga agtgatttct
    42601 tatatcaaac aagctgaacg actttctttt ttgctttggg gaactttgca gactgctata
    42661 ttgctctttt tatatcctat ttttagacgt ctaggtctgt ctttatttat ttttattatc
    42721 ttagttttga tattattggc actaaaaaga gtagtgctta gtcgaaagac aagatatttt
    42781 ttgagaggaa atcgtttaga ttgggcaaaa gctgtcgcat ttgaaagcaa tcgcaagcaa
    42841 agtattttaa agttttattc tctttttaca acagtcaaag gaatttctac aaaagtgaaa
    42901 gaaagaactt atctaaatcc tcttttaaaa ttagttaagc aaactccttc aaacctttgg
    42961 ctatcccttt atgctagagc ctttttacgt agttcagatt atttgggctt atttttacga
    43021 ctaatgctat taagctcatt atctgtattt tttatccata atctttattt gtcagtaagt
    43081 ttagcactca tttttaacta tttagttgta ttccaattac tttcacttta ttatcactac
    43141 gattaccatt atatgactag tctttatcct gaaaatagtc ggagcaagaa gaaaaatgtg
    43201 ttaagttttt tacgaggttt aagcttttta atgttaatcg tcaatatgct gtgttgctca
    43261 tcagcgccaa aagcactcat tttgattgta ggtatggttt tcatagcttg tatatatcta
    43321 ccttataagt taaagaagat cattgactaa gtagcctaaa acaagtaaaa taggggtaaa
    43381 cgactataaa agatagaaaa ggagggcgat aaggtgacaa cgacggaaca agaacttacc
    43441 ttgactccct tacgtgggaa aagtggcaaa gcttataaag gcacttatcc aaatggggaa
    43501 tgtgtcttta taaaattaaa tacgacccct attctacctg ccttagcaaa agaacagatt
    43561 gcgccacagt tactttgggc caaacgcatg ggcaatggtg atatgatgag tgcccaagaa
    43621 tggcttaacg gccgtacatt gaccaaagaa gatatgaaca gtaagcaaat cattcatatt
    43681 ctattgcgcc ttcacaaatc taaaaaatta gtcaatcaac tgcttcagct caattataag
    43741 attgaaaacc catacgattt attggttgat tttgagcaaa atgcaccctt gcaaattcag
    43801 caaaattcat acttacaagc tatcgttaaa gaattaaaac ggagcttacc agagttcaaa
    43861 tcagaagtag caacgattgt gcatggagat attaaacata gcaattgggt gattactact
    43921 agtggtatga tttttttagt agattgggat tctgttcgtc tgactgatcg gatgtatgat
    43981 gttgcttacc tgttgagcca ctatattcca cggtctcgtt ggtcagaatg gctgtcttat
    44041 tatggctata aaaataatga caaggttatg caaaaaatta tttggtatgg tcaattttct
    44101 cacctgacac aaattctcaa gtgttttgac aagcgtgaca tggagcatgt gaatcaggag
    44161 atttatgccc tcagaaaatt tagagaaata tttagaaaga aataatgcga gttagaaaac
    44221 gaaaaggtgc tgaggagcac ttagctaata acccacacta tgtgatatta aatccagaag
    44281 atgccaaggg ccgttggcat gacgtttttg gaaatgaccg tcctattcat atcgaagttg
    44341 gttcaggaaa gggcggattt atcacaggga tggccttgaa aaatcctgat attaactaca
    44401 ttggcattga tattcaatta tctgtcctaa gctacgcctt ggataaggta ttagcttcag
    44461 aagtacccaa tgtcaaactt ctgcgagtgg atggatcaag tttaaccaac tattttgaag
    44521 atggtgaggt ggatatgatg tatctcaact tttcagatcc ttggccaaaa accaagcatg
    44581 aaaaacgtcg tttgacctac aaggatttct tagacactta caagcgtatc ttgccagaac
    44641 acggtgaaat tcattttaaa accgataatc ggggcttgtt tgagtacagt ttagctagtt
    44701 tttctcaata cggcatgacc ttgagacaga tctggcttga cttacacgct agtaactatg
    44761 aaggaaatgt catgacagaa tatgaagaga agttctctaa taaaggtcaa gtcatttacc
    44821 gagttgaggc aaatttctag tagtattttg tttcaaaata tgataacata aaggagttga
    44881 tacagtatta acttctttag taatggagag gtcgcatagt ggcttagtgc gcacgcttgg
    44941 aaagcgtgta gtccttaacg gggctcgggg gttcgaatcc cctcctctcc ttgtgagtaa
    45001 aacaaagtgc atatccttgc attcctctta aattatggta taatgggctt aaataataca
    45061 gaaaggtggt gggatatgtc tcgccgcttt tgtattaagt ggattcccaa ggaccaatta
    45121 tcttagagaa gagcataaaa atagaggagg taatcaaaat agcaaataca tctattatcg
    45181 atatcgtaac caagacagta acacctgaga ttaaggcacc ttatgaatta gtagacgttg
    45241 aatatgacaa aatgggtagt gactacatcc ttagtatttt agtcgataag gaaggtggaa
    45301 tcacagtgga agatacatct gacttgacga atattattag tccgctgtta gatacgattg
    45361 atccagatcc ttttccaaac caatatatgc tagaagtctc tagtccaggt ttggagcgtc
    45421 cgcttaagac agctgacagt ttaaaagcag cagttggctc ttatatcaat gtgagtcttt
    45481 atcaagctat tgataaggtg aaagtttttc aaggagactt actagccttt gatggtgaaa
    45541 cgttgaccat tgattatctt gataaaacac gtcataagat cgtgaatata ccatatcaag
    45601 cagttgctaa ggtgagaatg gctgtcaaat tataactttt atttcaaagc actaaacttt
    45661 tttaggaacg cttaagcaaa tttgaaacaa cacctataga gtttatacaa gctaaacaaa
    45721 aggaattaag ggagccttta gggggctatt gatcgtatta atttaagaaa ggatttttgc
    45781 caagctttac aagcaaggta gataacatta tgagcaaaga aatgctagaa gccttccgta
    45841 ttttggaaga agaaaaacac attgataaag cagatattat tgacgcagtg acagaatcat
    45901 taaagtctgc ctataaacgt cgctatggtc aatcagaatc atgtgttatt gaatttaatg
    45961 aaaaaacagc tgattttcaa gtattcacgg ttcgtgaggt tgttgaagaa gtttttgaca
    46021 gccggcttga gattagtttg aaagatgctc ttgctatcag ttctgcctat gaattgggtg
    46081 ataagattcg ctttgaggaa tctgtcaatg aatttggacg tgtcgcagct caatcagcta
    46141 agcagactat tatggaaaag atgcgccgcc aaatgcgtga agtgatgttc aatgaataca
    46201 aagagcatga aggtgaaatt atgacaggaa cagttgaacg gtttgatcaa cgttttattt
    46261 atgtcaatct tggttcctta gaagcacaat tgtctcacca agaccagatt ccaggtgaaa
    46321 ctttcaaatc acatgaccgt attgacgttt atgtctacaa agttgaaaat aatcctaaag
    46381 gagttaacgt ctttgttagt cgtagccatc cagaattcat caaacgtatt atggagcaag
    46441 aaattcctga agtctttgat ggtactgttg aaatcatgag tgtctctcgt gaagcaggtg
    46501 accgtaccaa ggttgctgtg cgcagtcata atcctaacgt tgatgccatc ggaacaattg
    46561 ttggacgtgg tggaagtaat attaaaaagg tcatcagcaa gttccatcca aaacgtgtag
    46621 atgctaagac ggggcttgaa attccagttg aagaaaatat tgacgtgatt caatgggtag
    46681 atgatccagc tgagttcatc tacaatgcca ttgctccggc tgaagtagac atggtacttt
    46741 ttgacgatga agatcttaaa cgtgctacgg tagtagttcc tgatagcaaa ttatcattag
    46801 ctatcgggcg tcgcggccaa aacgttcgtt tagcggcaca tttgactggc taccgtattg
    46861 atatcaaatc agctagcgaa tatgatcgtc ttgaggcgga aaaagaagca gcaacagttg
    46921 tggaagagcc agttgttgac gatgttatga ctgccgagga agtgtaagaa aagaggtgtt
    46981 tgatgtctaa agtcaaaaaa atacctttac gaaaatcact tgtttctggt gaaattattg
    47041 ctaaacgaga tcttcttagg attgtaaaaa ctaaggatgg tcaagttttc attgatccaa
    47101 ctggtaaaca aaatggtcgt ggtgcttata tcaaattaga caatcaagag gccttaatgg
    47161 ccaagaaaaa acaagttttc aacaggagtt tctcaatgga cattccagaa agtttttacg
    47221 atgacttgat tgcttatgtt gatcacaaaa tcaaaagaag agagttaggt cttgactaat
    47281 ttagaaagat tatctagtct tattggtcta gctcaacggg ctggaaaagt gatttcaggt
    47341 gaagaactag tagtaaaagc tattcaacac cagcaggtaa tattagtatt tttagccaat
    47401 gatgctggtc ctaatgtgac aaaaaaagtg acagataaaa gtaattatta taatgtagaa
    47461 gtctccacag tgttgaatgc actggaatta agtgctgcac taggtaaacc aaggaaggtt
    47521 gctgccgttg cagatgctgg attttcaaag aaaatgagga ctcttatgga atagatgaat
    47581 aggaggacac aaattgtcaa agaaaagatt acatgaaatt gccaaggaaa ttggtaaaag
    47641 tagtaaagag gtggttgaac acgctaaata cttaggatta gatgtgaaaa gccatgcatc
    47701 aagtgttgaa gaagcggatg cgaaaaagat tatttcaagt ttttcaaagg cttctaaacc
    47761 tgatgtgaca gcttctcaaa cagtcaagcc caaagaagtt gctcaaccct ctgtaacagt
    47821 ggtcaaagaa acaggttctg agcatgtaga gaaaacacag gtctctaagc caaagagtcg
    47881 taattttaaa gctgaaagag aggctcgtgc aaaggaacag gctgctcgaa aacaagcaaa
    47941 tggctcttct catcgttctc aagaacgtcg aggaggttat cgccagccca ataatcatca
    48001 aactaacgaa caaggagata agaggattac ccatcgttct caaggtgata caaacgataa
    48061 gcgtattgag cgaaaagcat cgaatgtatc acctagacat gataatcatc agctagttgg
    48121 tgatcgtaac cgttcctttg ctaaggagaa tcacaagaat ggtcgattca caaaccagaa
    48181 aaagcaagga cgacaagagc ctcaatcgaa aagtcctaaa attgatttca aagctcgtgc
    48241 tgctgcctta aaagctgaac aaaatgctga atactcacgc caaagtgaaa cacgttttcg
    48301 tgcacagcaa gaagctaagc gtttagctga gttggcaaga caagaagcta aagaagcggc
    48361 tttaaaagca caagctgagg agatgagcca tcgtgaagca gcactgaaat ctattgaaga
    48421 agcagaaact aaattaaagt catcaaatat tagtgctaaa tctactgctg ataatcgccg
    48481 taaaaaacaa gcacgtcctg aaaagaatcg tgagttaact catcattcac aagaaggaca
    48541 aaagaaaaat aagaagagtt ggaatagtca aaaccaagtg agaaatcaaa aaaatagtaa
    48601 ctggaataaa aataaaaaga ccaaaaaagg caaaaatgtt aagaatacta acaccgctcc
    48661 aaaaccagta accgagcgta aattccatga attgccaaaa gaatttgaat atactgaagg
    48721 catgacagtt gccgaaatcg caaaacgtat caaacgcgaa cccgctgaaa ttgttaaaaa
    48781 gctgtttatg atgggtgtta tggcaactca aaaccagtct ttagatgggg atactatcga
    48841 attattgatg gtagattatg gtattgaggc taaggctaag gtagaagtag atgatgctga
    48901 tatcgagcgc ttctttgagg atgaaaatta cctcaatcct gaaaatattg tagaacgcgc
    48961 acctgttgta actatcatgg gacacgtaga ccacggtaag acaactttgc ttgatacttt
    49021 gcgtaactca cgtgtggcaa caggagaagc tggaggaatt actcagcata ttggtgctta
    49081 ccagattgaa gaagctggca agaaaattac cttcttggat actcccggac acgcggcctt
    49141 tacaagcatg cgcgcacgtg gagcttccgt taccgatatc accattttga ttgttgcagc
    49201 tgatgatggt gttatgccac aaacgattga agcgatcaat cactcaaaag ctgctggtgt
    49261 tccaattatt gttgctatca acaaaattga taaaccaggt gctaatccag aacgtgttat
    49321 cgcagaattg gcagaatatg gtatcatctc aactgcttgg ggcggagagt gcgaatttgt
    49381 agagatatct gctaaattta ataaaaatat tgatgaacta ttagaaacag tccttttggt
    49441 tgctgaagta gaagaattga aagctgatcc gacggttcgt gctattggta ctgtgattga
    49501 agcacgctta gataaaggta aaggtgctat cgctacgctt cttgtccaac aaggaactct
    49561 tcatgttcaa gacccaatcg ttgttggtaa tacctttggt cgtgtccgtg ccatggtaaa
    49621 tgaccttggg cgtcgtgtta aatctgcgga gccatcaaca ccagtttcca ttactggttt
    49681 gaacgaaaca ccaatggctg gtgatcactt tgctgtttac gctgatgaaa aagctgcgcg
    49741 tgcagctggt gaggagcgat caaaacgtgc cctcctcaaa caacgtcaaa atacacagcg
    49801 tgttagcctt gataatctct ttgataccct taaagcagga gaaatcaaga ctgttaatgt
    49861 catcatcaaa gcagacgttc aaggttctgt tgaagccctt gcagcatctc ttgtaaagat
    49921 tgaagtggaa ggtgtccgtg tcaatgtcgt tcactctgct gtaggtgcta tcaatgagtc
    49981 tgatgtgacc cttgctgaag catcaaatgc tgttattatc ggtttcaacg ttcgccctac
    50041 cccacaagct cgtcaacaag cagatacgga tgatgtggaa attcgtcttc atagcattat
    50101 ctataaagtc attgaagaag tagaagaagc catgaaaggg aaacttgacc ctgtttacca
    50161 agaaaaaatt cttggtgaag ccattattcg tgaaaccttc aaagtttcta aagtgggaac
    50221 aattggtggc tttatggtaa tcaacggtaa ggtgacacgt gattcgagtg ttcgtgttat
    50281 ccgtgatagt gtcgttattt ttgatggtaa actggccagc ttgaaacatt acaaagatga
    50341 cgttaaagaa gtcggtaatg ctcaagaagg tgggttgatg attgaaaact ttaacgatct
    50401 taaagttgac gatactattg aagcctatat tatggaagaa attgtgagaa aataggggct
    50461 aagaaggtct gagatgtgac gtttttcctc tgtcggaaat aatgacttgt tctaccagat
    50521 gagctacttg gggcattcct tccagtctcg tcatggaatt ctcagattcc ctttagttgt
    50581 cgttatcaaa acaggtagca atgtcataag ctgggctttc agcctagctt ttgttttaaa
    50641 aatgtggaaa ggaaatggct atggctaatc atcgtattga ccgcgttggg atggaaatca
    50701 agcgcgaagt aaatgatatt cttcagaaaa aagtgcgtga tccacgcgtt cagggagtaa
    50761 cgattacaga agtgcaaatg cagggtgact tgtcacttgc taaagtttat tacactatta
    50821 tgagtgactt ggcatctgat aatcaaaaag cacaaacagg gcttgaaaaa gcgactggaa
    50881 cgattaaacg tgaacttggc aaacaattga ccatgtacaa aattccagat ttggtgtttg
    50941 aaaaagacaa ttccatcgcc tatggtaata aaatagatca actgttacgt gagcttgata
    51001 aaaaagatta aattaaaaac ctttaaggta tcttattaga gtcaccttaa gggttttttg
    51061 tttttagtaa gctttttgaa tcgtatcaat gatttgatat tgtgcagtct tggcttcttc
    51121 aattggatag attgggtaaa catgattcat tttatcagcg acgataagtt catgttgatg
    51181 acctttggca gttaatatat catcaaattt cttaacatct gggtagaaaa tttcatgtgt
    51241 accaacaaac atagtaatag gtgctagccc tgatacatct ccattaattg gactaacata
    51301 tggatgtttg gtgttgtttg ggtcacggcg tgcccaaatt tccccaactt tacgtaggcc
    51361 ccaagctgaa agaatgggat cattactttc atagctctca atatctggat ttgacatggt
    51421 tacatctaac catggtgata agagaacaat gtcttttggt tgttttaaac tttcattttt
    51481 tagggctaat gctaaaccaa gcgctagtcc accacctgct gaatcaccca taatagtgat
    51541 attttgtgca gttgtttctt taagagtatc tctgtaaagg tcaaccaatt ttggcatagc
    51601 atcactgtaa gagtaagtag gtgcttttgg atagattggt aagataatct tagcatcaag
    51661 actagttgat aaggttttta gcatgtcgat atgataagta gttgggttgt ttaggtaaga
    51721 gcccccatgt aaatagaaaa tgaccttttg attggcttta ttgctggggt tctcattcca
    51781 agtatgaact tgcatattat caacagtttt agtgactaat gtgccattta cctgttcttc
    51841 tttaagatca aagcctttat ttgaagcttc tccagcagag ttgacatatt gatcaaactt
    51901 agtttcgtct tgctctgaat aatagccttt gtctcctttt aaccaaaagt atttctctat
    51961 aaaccagctt ttccaagatc tagaactggc atcaacttga gtgctagctc ctattgctag
    52021 agtaagtcct agtaaaataa gagtgctttt aagtgtcttt ttcaatgagt tctccttatt
    52081 attatcattt ttttatcata taatcatatc ataaatgaaa aaattgtcaa cttaagaaat
    52141 aaaatcatta gaaactttat atatttacaa atgtagataa atatgatata atatatctac
    52201 aaatgtagat taaaaggttg tgagttgatg aatcaaaata tttcagctgc cgaatgggaa
    52261 gtcatgcgtg tggtgtgggc cagtggtgat attaaaagta gtgatattat tactatttta
    52321 aggaaaaaat atcaatggtc agattctacc attaaaacct tgattgggcg tttggtggaa
    52381 aaaaaggctt tgggaactta ccggcaagga agagcttata tttatcaagc tcttttggat
    52441 gagactttgc tacaaaaaga agcactagcg actgttttag acggtatttg tcagcggcaa
    52501 cacacgcatc tacttcttga acggctttat gacttaccga tgaccttaga ggaaattgag
    52561 gcattccaag agctactaga agtcaaaaaa gaaaatgcag ttcttgaggt gtcgtgtaat
    52621 tgcctgcctg ggcagtgcca ctgtcagaaa aaggagacgt attaatggct aaagagatat
    52681 ttttagtgga gggaatgagt tgtgcctctt gtgctctaac aattgaaaaa atggtcaatc
    52741 aattgcctga agtagaacag gctgttgtga atttagcgac cgagaaactc acggttactt
    52801 atcaagatga cgatttagaa acggccaaag ttattcaagc ggtaaaagct gctggttatg
    52861 gtgcacaagt ctttgatgaa catgcaaaac acatgcaaac aggtcgtcgt gacgaagacc
    52921 taaaggttat ttggtctcag gtcttgtggt ctgccctatt caccattcct atattatacc
    52981 tagctatggg tcacatggtg ggcttatggc ttcctccatt tctgcaacca gatcgctatc
    53041 ctttcgttta cagctttagt cagctactct tgacgattcc agtcttagta ttaaatcgtc
    53101 attattacca taatgggttt aaagctttgt ttaagggata tcctaatatg gactccttgg
    53161 tagctttagc aaccagcttt gcttttgctt atagtcttta tggagtggtt gaaatcagtt
    53221 tgggccaggc caactttgtg cactcccttt attttgaatc ggtggtagtg attttgacac
    53281 tcattggtct aggaaagtat tttgaaagtc gttctaaagg ccgtacttcc caagctattc
    53341 aaaagctctt atccttgaag gctactgttg tgagggtatg gagaaatagc caatggcaat
    53401 tgttgccgtt agaagaggtt agctatgatg accttgtcct ggttcaacca ggtgaaaaag
    53461 tttctattga cggtattatc gtggaaggac atagcagttt ggatgaatcc tttttaactg
    53521 gggaaagttt gcctgttgaa aagggagaaa aagataatgt ctttgcgggc agcttgaatg
    53581 ggccaggcgc cctcacgatt aaaccagata agcttgggaa tgataccttg ttagcacaaa
    53641 ttatccaact agttgagaat gctcaagaaa ataaagcacc tattgcagct attgctgata
    53701 aggtctcagg tgtctttgtt ccggtggttt tggtattagc tctgttaaca ggggtgtttt
    53761 ggttggtatt catgcaggaa agtcttcgtt ttagtttgac aacagccatc gctgttctag
    53821 tcattgcttg cccttgtgcg cttggtttag caacgccgac agcgattatg gttggaacag
    53881 ggcgtgcagc tgaaaatggt attcttttta aaggtggtga catcttagaa caagcccatc
    53941 aggtagatac ggttgttttt gataaaacgg ggacgattac ggaggggaaa ccaagtcttc
    54001 aaaagctcct aactttttcg ggagatgatc accttatctt gcaagaagct gcttccttgg
    54061 aggcctattc tcaacacccc ttaggggagg ctattgttcg tgctgctcag gaagctggtt
    54121 acgatagtct accagtggaa gagtttgagt ctttaaccgg cctaggagtt actggtcagc
    54181 ttgaagggcg tcgtttggcg attggaaatg ctgctttaat gggaattctt ggtatcgatt
    54241 tatcttgtgt tcagtcagtt tgtgctaagg cttctgagaa aggccaaacc cttgtatatt
    54301 atgctaaaga ggggcagcta cgagctcttt tcagtattgc tgacgctgtc aaagaagata
    54361 gtcaagctac cgtcgaagct ttgcatcaac tgggaattca caccatcatg ctaacaggtg
    54421 accacgatgc taccgctaag gctattgcct ctcaagtggg gattacagat gtgatcagtc
    54481 aagtcttacc tgatcaaaaa gcaggcgtga tagcagacct ccgctctcaa gggagaaaag
    54541 ttgcaatggt aggtgatggt attaatgatg ctccggcatt ggctgtagca gacattggga
    54601 tagctatggg gtcagggaca gatattgcca ttgaatcggc ggatgtgatt ctgatgaaac
    54661 ctgatatgct ggatttggtg aaagctatgt cattgagtcg agcgactatg aggattgtca
    54721 aggaaaattt attttgggca ttcatttaca atgtcctcat gattccagtg gccatgggct
    54781 tacttcatct ttttggaggc ccattattga acccgatgtt agcaggtttt gccatgagtt
    54841 ttagttcagt atcagttgtt ttgaatgccc tgcgattaaa aggaaaaacc atttaaagga
    54901 gaatacaaaa tggaaaaaca ttatcaggtt acaggaatga catgtgacgg ttgcgcaaga
    54961 acggtcactg aaaaattatc agctgtcccc ggtgtgcaat cggtccaggt aaatttggaa
    55021 aaaggacagg ctaaggtgac aggacgtcct ttaacgttcc tactcaagcg tgctttgaag
    55081 gataccaaat ttgaattaca tcaatcatct taggttattt tggtagcctt acttcatctc
    55141 aaaagaggtt ccagtttttt aatctgggct tctttttttg tggtcactca taaagactct
    55201 gacgttagca ggtgtgttcc gagcaaaata aaaacacctc tctggaagca aatcactttt
    55261 gccagaaggt gtttaaggac gatgcgctga caggctgtcc attcttgatg aaacggttac
    55321 tccttgtttt cgtgggctac taataattgt gtgaactgac tataacgttc gatgacgtcc
    55381 tcagttattt gcgaatctgt aacaacagca tcaatgttgt ttaaatggta aaaaatgaag
    55441 aagtcgtagg cattgaattt ttggttatct accaagaggt atttttcaat agaattatta
    55501 aaagctagct tttgaatctc tccttcagtt tcgctataag ttgcaatatc gtttttataa
    55561 ataccattac agctaataaa agccttggca aattttaagg atgagatatt ttgactggca
    55621 agggacccta caaaagctcc tgtaatagat cggtattcac cgccgataag aatcaggtca
    55681 atggtttcgc tgtcctgaag gatgttaaag acagggaggc tattggtcac aatgcgaatc
    55741 tgacgatttt ttaattgctc agcgaaacat tctaaagttg ttcctggacc aataaagatt
    55801 gtttcaccat cattgactag ttgtgtcgca tatgaagcta gttcccattt ttcctttgtt
    55861 tgaacggttt gtttttcaat atttgaccgc tcttttttat taggcatggt aatgctttgt
    55921 gcacctccat ggatgcggat caatttgccg gctttttcca gttcatctaa gtctctacga
    55981 actgtcatat cagaaacgtt taaagtctga ataatatcat tcacagtaac aataccttgc
    56041 tcattgacta tttcggtaat ttttagaagt ctttctcttt ttaacatcta aggggctcct
    56101 ttctatagtt tatttactta tgtttatcat agcatataga ccttcatatt tcaataaaac
    56161 aaaataaaca aaacaaaaac aaacatatag aacaaaaaat attgcgtaaa aatgttgaat
    56221 tatgttgaag gttatactat aatgattttg taaacggtta ccaatttgtt gatgatgaga
    56281 tgacagttgt taaaaattga tacttataga aaggcggtag ggagtgtttc ctaatattct
    56341 atttactgaa gcaaggacgc agccagagct ttttgatctt gttgctagct acttggaaaa
    56401 ggttgggtat gtgacgcaag agtatcatca ggctttagtg gagcgtgagg cggtatttcc
    56461 gacaggactc aaagtggacc tcaaagatgg gtcagatatt ttgtatgcgg ctattccgca
    56521 tacagaaacc aagtattgct tggttgatca agtggtctat gttagaaata gtcaagccct
    56581 tacctttaag cacatgatta atccagagga agactgtttg gtaacggatt tcttctttat
    56641 tatcaatagt caaaacgagg gtcaaacgac gattctatcc aatctcatta ccttctttat
    56701 tacgaaaggc aatcttagct atctagccag tctaaaagat gataaacaag ctatttcaaa
    56761 ctatttaata gaaaaaggag tgtttcagca tgattaaaat tctagcagcc tgcggtgcag
    56821 gggttaactc aagccatcaa attaaagatg cgattgaaac tcagatgagt gatcgtggct
    56881 atgatgtgca ttgtgatgcg gtgatggtca aagacatcac agaagaattg gtgtctcgtt
    56941 atgatatttt tacgccgatt gcaaaaactg acttgggatt tgagatgcca attcccacag
    57001 tagaagcagg accgattctc tatcgtatcc caatcatgag tgagcctgtt tttgctgaat
    57061 tagagcgcgt gattaaagaa aaccatttgc agtgagttaa taaaaacata aggagacaag
    57121 atgatgcaac cttttttaga cattattaac aagattctgg gatttcctat tcagttggga
    57181 tcaggtgtgg tcatgctgat tgtcatgaca ggtttagcca tgattttcgg ggttaaattc
    57241 acaaaggcac tggaaggcgg gattaagtta gctatcgctc ttacaggtat tggagccatt
    57301 attgggattt tgacgggggc tttttcagag tctttgcagg cctttgttaa aaatacaggg
    57361 atcagtttaa acattattga tgtcggttgg gcaccgcttg caacaattac ctggggttcc
    57421 ccttataccc tttatttctt gctggtgatg ctggtggtta atattgtcat gattgtcatg
    57481 aaaaaaacgg acacccttga cgtcgatatt tttgatattt ggcatttgtc tatcacaggt
    57541 ctattgatta tgtggtatgc tgatcacaac catttgccag tccttgtgtc tcttttgatt
    57601 gctactgtgg cagttattct tgttggggta ttgaaaatca ttaactctga tttgatgaaa
    57661 ccgacctttg atgaccttct tgggacaggg tctcaatcac caatgacttc aactcacatg
    57721 aactacatga tgaatccaat cattatggtc ttagataaga tttttgacaa ggtctttccg
    57781 gggctagata aatatgactt tgatgctgct aaattgaaca aaaaaattgg cttctggggc
    57841 tctaagttct ttatcggaat ggctctaggt tttgtgattg ggattatggg agatcctcat
    57901 ttcactgttg aatctatcaa aaattggttt ggtctaggat ttacagctgg tgcctgcttg
    57961 gaacttttct ctttgattgg ctcttggttt atcgcagctg ttgagccttt gtcacaaggg
    58021 attaccaatt ttgccaatgc tagaatgcat gggcgtcgtt tcaatatcgg tttggactgg
    58081 cctttcattg ctggtcgcgc tgaaatctgg gcctgtgcca atattcttgc cccaatcatg
    58141 ttgattgaag ccgttctcct atcaaaagtt ggcaatggga ttttaccatt ggcggggatt
    58201 attgctatgg ggatgacacc agctcttctt gtggtcacac gtggtcgttt gattcgcatg
    58261 attatttttg gttccctctt attgccatta ttcctcttgt caggaactat gattgctcca
    58321 tttgcgacag agttggctaa aaaagtaggg gcttttccag caggtacaag cgctggttcc
    58381 ttgattacgc attcaacact tgaaggacca atggaaaaaa tttttggtta tgtgattggt
    58441 caagcgacaa caggtcagat tgcctcaatc atcacgctaa tcatctttgt ggccatttac
    58501 ctaggtctct ttgcttggta tgctaaccaa atgaaggcac gtaacgctga gtatgcgaaa
    58561 acaatgaaat aaaatcaggt caggtgactg actaaaaaat tagggagaat agcagataac
    58621 tgcgtaaggt atttctgcct taccccctaa cgtgaaaaga gtatttctca tgtaaggcaa
    58681 ggcgctctgt gggaactcac aagtgctttg tcttgaaaga aataatggaa gacactaaga
    58741 ctactggcaa tcatcttgat ctaaggacag gtaatcatgt cccccttctc tagattggca
    58801 agcgttttgg gttagaaaag gaaaagctat ggctattatt ttaggtgcag atgcacacgg
    58861 aaatgcatta aaagaattga tcaaaagttt tcttcaagaa gaaggctatg atattattga
    58921 cgtgactgat attaacagtg attttattga taacacatta gcggtggcga aagccgttaa
    58981 tgaagcagaa ggtcgtttag gcattatggt agatgcttac ggagcaggtc cctttatggt
    59041 agccacaaaa ttaaaaggaa tggttgctgc tgaagtgtca gatgaacgct ctgcttacat
    59101 gacgcgcggt cacaacaatg cccgcatgat cacaataggg gcagagattg taggtccaga
    59161 attagcgaag aatatcgtca aaggttttgt gactggtccc tacgatggtg gtcgtcatca
    59221 aattcgtgtt gacatgctca ataaaatggc ctaaaggagg ataaagtgat gaaaattgcg
    59281 attggttgtg accatattgt caccaacgaa aaaatggctg tttctgattt tttgaaatct
    59341 aaaggctatg acgttattga ctgtggcact tatgaccata caagaaccca ttaccctatt
    59401 tttggaaaaa aagtcggcga agctgtggtt aatggtcaag cagacttggg tgtttgtatt
    59461 tgtggaactg gagttggcat taataatgcc gtgaacaagg taccaggtat tcgttcagcc
    59521 cttgttcgag atatgacaac agcgctttat gccaaggaag aattgaatgc caatgtgatt
    59581 ggctttggtg gtaaaatcac tggtgaactt cttatgtgtg atattataga tgcttttatc
    59641 aaggcagaat acaaagaaac tgaagagaat aagaagctaa ttgctaaaat agcccacttg
    59701 gaaagtcatc atgccaacca agaagatcct gattttttta cagaattttt ggaaaaatgg
    59761 gatcgtggtg agtatcacga ttaggaagaa gagatgagtt taacagttat cttaaatcct
    59821 tctgtcgcta tttcctatcc tttagattgt ctggctatgg acacggttaa tcgtgttgac
    59881 agaacggcaa aaacagctgg tgataaggag ctaaatgtga ccagaatgtt agcaaaagct
    59941 ggtcagttat ggcaacagga tttagtggtg gtaaactggg tgactttatc attcatcagt
    60001 tacaagaaca gggcatttct aaccaatttt tcaaaatcaa aggggaaacg agaaattgta
    60061 ttgctgtttt acatgaaggc atgcagacaa aaattttgga agctggtccc tacagtgatg
    60121 tggacgaagc cgaagtctct ttgagccaca tgagtactat tgctaagccg tttgatgtct
    60181 taacttctca ggcagtctgc ctaggagact agctactcac tattatcaag atttgatgac
    60241 tatggcaact tttaaacaat tatatcagca acttcaagta agagaggtat cacatgacaa
    60301 tcacagcaaa taaaagacat tacttagaaa aagtgagcca tcaaggaatc atatcagctt
    60361 tagcttttga tcaacgaggt gcactgaagc aaatgatggc agcacatcaa gaaggagaag
    60421 cgacagttac acagatagaa acattgaaag ttctcgtttc tgaggaattg acgccttatg
    60481 cttcatctat tttattagat ccagaatatg ggttgctggc tactaaggta agagctaatc
    60541 agacaggctt actgttagct tacgaaaaaa caggttatga tgctacaacc actagccgtt
    60601 tacccgattg cttagtggaa tggtcggtca aacggttgaa agcagcaggt gcagatgcta
    60661 ttaaattttt gctctattat gatgttgatg gagatgaaca aatcaattta caaaaacaag
    60721 cttatattga acgcattggt tcagaatgta cagctgaaga catccctttt tttcttgaac
    60781 ttttgagtta tgatgagaga atatcagata acaacagtgc ggcatacgca aagcttaagc
    60841 cacataaggt taacggtgct atgtcagtat tttcggataa gcgttttggc gttgatgtgc
    60901 taaaagtaga ggttcctgtt aatatggctt atgtagaagg ttttactgaa ggggaagtcc
    60961 attacagtca agctgaggct attaaagctt ttcaagacca agaagctgcc agccacctcc
    61021 cttatatcta tttgagtgca ggcgtatctg ccaaactttt tcaagagaca ttatactttg
    61081 cagcagcagc aggtgctcaa tttagcggtg ttttgtgtgg gcgtgccacg tgggcaggat
    61141 ccgttccagt ttatattact aaaggagagg acgaagcaag aaagtggcta tgcactgaag
    61201 gcttccaaaa tattgacgag ttaaacaggg tactcgaaga gacagctagc ccttggacgg
    61261 aaaaaatcta aaacaacctt atcctatcaa gcagctctca ttgatgtgat aagataagta
    61321 tggggataat tgtttgaatc ttttgtagca aggatgaaaa tgggttttat ccttgctttt
    61381 ttatccttac attttatctt tttctactta ttttttaaag gaaaacgtgg taaactaaaa
    61441 gaagactaaa agacaatagg gtagcttatg acaattgata tgtgggaaat tttaaatatc
    61501 atcgggacca ttgcctttgc tctttctggt gctattgttg ccatggaaga agaatttgat
    61561 attttaggga tttttatttt aggtttcgtg acagcctttg gaggcggagc cattcgaaac
    61621 accctaattg gtttacctat agaggcctta tgggggcaaa agccagaatt cacttgcgct
    61681 ttctttgcta tggttttgat tatgcttttt cctaagctaa tagctagagg ttgggtacgg
    61741 gcagttgttt tgactgatgc cattggtctg gcagctttta gtgtccaagg agccttgcat
    61801 gctgtccgtc ttaaccagcc tttaagtgct gtcattgtag cagctgtgtt gactggtgca
    61861 ggcggtggtg ttgtcagaga tattctggca gggcgaaaac ctagtgtttt gcgtagtgaa
    61921 atctatgctg ggtggtctat tcttgcagct attgttttgc attttaaact agcagattca
    61981 acgattgaat gttatgcctt ggttgtttta ctcacgactt tacgcatgat tggcaaccgt
    62041 aaaaaatgga acctccctaa aatcaaatgg aaagaggaaa gataggatga ttcaactaat
    62101 tgcaattgat ttggacggca ccttattaaa ccaggacaaa cagattccaa aagagaatat
    62161 cacagccatc caagaagcag ctcagtcagg cttaaaaatt gtcttatgca caggccggcc
    62221 tcagtcaggg acaagaccct attttgacca attaggtttg acacaagagg aattcctcat
    62281 tatcaataat ggctgtagta cttatagtag tcctgactgg caattacgcc attcaaaaat
    62341 gttgaaggtt tcagatattg aattgctgga agagctaagc caaagttttc cagatattta
    62401 cctgacttta actgaggaaa acgattattt ggtgcttgaa gaagaagtgc cagaccttgt
    62461 gcaggaagat ggagatttgg tatttaccat tgtcaagcct gtctccttag cagagctgtc
    62521 ggacactcct cgcctgattt ttcaagccat gtacttagga gaaaaagctg cgctagatgc
    62581 ctttgaacgt gcggtgagaa atcagcttag tcagagtttt catgttgttc gtagccaaga
    62641 taatatttta gaaattctcc ctcagggagt cagcaaggca tcggctctca aagaattagt
    62701 agaagatttg ggtttaactg ctgaccaagt gatggctatt ggggatgctc ccaatgacat
    62761 tgagatgtta acttatgctg gtttaggagt tgctatggaa aatgcttcag cagctatcaa
    62821 gccattagct gacaaagtca ctttgactaa tgatatggcg ggtgtggccc aggctatccg
    62881 tcagtttgca cttgcagctc aaaaagacta actattatat aaaaaaggtt cccaaaagga
    62941 acctttttac gttaatagag gcaagcccat agcagccatt tcttcggcag gaacgatcat
    63001 gtcatctgaa atccagtttg tcaagacaga aacaatagca ttgctccaaa aaaggcgctt
    63061 atagtgcgat tgttttttgt cttttaattt ttgataagct ttcagacgtt tagtgactaa
    63121 tcgtgttaga agatggtgca ggtgatgttt gaaaatcatt ttaagaagct gagcttcttt
    63181 tttagcttca gtaaaaagat agagccaggc ttgataagcc tgagttttaa tatcaaattg
    63241 ttttagtcca cgaaaaatac gacggataac ccctactaac agttgttcta taatggcttc
    63301 tttagaggta taattacgat aaaaagcgtt acgagatact cctgctttcg tcaccaattc
    63361 tgaaatcgta atatcaccta aaggttttgt ttctagaaga ttcagtaagg cgatttccat
    63421 agattcacgt gctatgcgtc gtgtttcttt attaaattgt gttaagtttt gaagtgatct
    63481 ttttgagagt gctttatcag tcatcacaaa tacctttcaa gtgttacctc tgatgagtta
    63541 tcagtagcaa aaaccgactt aataatgata taattttatg ggaaaagtct tagtttgtca
    63601 actaaagtta gttatcagga gcctcattac ctccttgtat agctctattg gatgacttta
    63661 ctaactattg aaaaggctag taataaaaca taggatttaa tgattagtta ttaccattag
    63721 cctagacatc ttagcgaagg cttaataatc tggtctttgt taccgaacac aaattagaga
    63781 aaaagaagga taaaaaatga cttggaaaat tgtaacagat tcaggatgtg atcttagaag
    63841 tttgactaga caatccaaag agttgcgctt tgaacgtgtg cctttgaccc tacagattgg
    63901 cacagaaatt tttagagatg atgatggatt agatatcgat aatatgatga caactatgta
    63961 ccagtcgtct aaagcaacga catctagctg tccaagccca gaagcctttt tgcaggccta
    64021 tagaggtgca gataatgtta tcgtgatgac aattacaggg accttatctg gcagtcataa
    64081 tagtgcacga ctggctaaaa atgaacttct tgaagaaaat cctaatgtca atattcacct
    64141 aatcgattct ttatcagcag gtggcgagat ggatttgctc gtactggagc ttgagcggtt
    64201 gatcaatctt ggattatcct ttgaagaagt tgtcaaacag atcacagctt atcagcaaaa
    64261 aacacgtttg atttttgtgc ttgccaaggt tgataatttg gttaaaaatg gtcgactgag
    64321 taaattagta ggtaaagtaa ttggcttact caatattaga atggttggga aagctagcaa
    64381 taaaggaacg cttgaacttc ttcaaaaagc gcgtggtcaa aaaaaagcag tttctgcttt
    64441 gatagaagaa attcaaaaag agggttatgt aggcggaaaa gtttacattg ctcatgctca
    64501 aaatccaaaa atttgtgagc agatcagtga aaaaatcaaa tctttatatc ctgatgctgt
    64561 gattcaaact ggaaggacct caggtttgtg tagcttttat gctgaagacg gaggactttt
    64621 aatgggctac gaaatttaat gctatctaac aaaacaaaaa gctagactct tttgatttga
    64681 gctagctttt ttaagatatc aggaagacta atcactaaga tagccgtcta aaacgtttat
    64741 tgattgattt tacgaaaaat ttttgtatta ctcttttgat gattgcttgt ctcctgagtc
    64801 agaaggttct gaagaggtct gaggtggaat tggatcagga tgactaggtt gtggcgtaac
    64861 atctgaagct gaagattctg agcttgggtc taaagtaggt gactgggaat tatcataagt
    64921 atctgagacg tctcctggga aaggtgtcca gtaagagtta tctgttattt ctccactttg
    64981 tcttggaaat tcatcaataa tgggttttgc tggtaaaata gcgtctaacc gagattgtaa
    65041 agcggctttt ttacctttgt tacttaagtc gttaactgct ttttgggcga tatctttaag
    65101 attttgattg agagtctcct cagcagcttt aactgcttga gtagctgcat cttcttgctc
    65161 ttgctttgct ttggcaacgt ttagctgttc ttgtagcgtt tttttcttag aagattctgc
    65221 taatttatca acagctttct gggcttcttg gatagcagct gcagtggcta aacgatcagc
    65281 gtcattaact gctttaactg ctttttttag taaactagca gcacttttag aatgtttagc
    65341 taccttatct tgcgtttgag ggtgggatcc aaaaataagg caggagccac ctattagagt
    65401 gatagttaga acactcaaca tccaataaag cgcctctttt tgtgatttag tcatggaatc
    65461 tcctttatga tattgtttca tcgtagccat attatacctc taattaaacg aaatgaaaag
    65521 atttgtgcaa aaacaaatga tgtaaaatat cggaaaagcc taacacctta tcaaaccaat
    65581 aatatgcaaa tgttgacatc ggtatacaca gaaacgctta aaaaaacctt gtgataaaga
    65641 ccgtaataca ttaaaataga atagactaaa aaattgagcg aggacaatat tgtgtcagta
    65701 aattggcaag acattgcatt tcatttcttt ggaggcttag gtctctttct tttcagtatc
    65761 aagtatatgg gagatggtct gcaacaagca gcaggagata aactaaggta ttacattgat
    65821 aaatacacca gtaatccctt ttttggtatc ttagtcggaa ttgccatgtc tgccttaatt
    65881 cagtccagtt caggcgtaac tgtgattacg gttggtttgg tttctgcggg tttgctaaat
    65941 ttgcgacaag ccattggaat tgttatgggg gctaatattg gaacgactat cacttcgttt
    66001 ttaattggtt ttaaactagg agattacgcc ttgcccatga tttttattgg tgcagcctgt
    66061 cttttcttta cctctaataa aaagctcaac aattttgggc gtatcatttt tggtgtcgga
    66121 ggaattttct tctcgctgaa cctaatggga gatgccatgg atcctttgaa atctgtgtca
    66181 gcctttcaaa attatttagc gacattaggt gataaactct tccaaggtgt ctttatcgga
    66241 acggctttga ccatgttgat tcagtcatcg gcagccatta tcgggatttt acagggtctg
    66301 ttttcaggtg gtcttttgac tttacaggga gctattccta ttttgttagg ctcaaatata
    66361 ggaacctgca ttacagctgt cttagcagct ataggttcaa atattgctgc taaacgtgtg
    66421 gcagcagctc atgtgttatt taatttgatc ggtacaatta tttttatgat tatcctagtc
    66481 ccattcacat cattgatgtt atggctacaa tcaaagttga gtttaacgcc tgagatgact
    66541 atcgcttttt ctcacggttc ttttaatatc actaatacca tcttattaat tcctttcatt
    66601 agtctactag ctatgattgt gactagactc attccaggag aagatgaagt ggtcaaatac
    66661 gaagcccttt atttagatcg cttacttatt acccaagccc cttctatcgc actaggaaat
    66721 gcccacaagg aattggttca tttagcctct tatgcgattc aagcttttga agcttcttac
    66781 agttatatta tgacagctga cggtaaattt ggggaaaagg tcaagcgtta tgaaagagca
    66841 gttgatacca tcgatgagga gttaaccact tatttggttg atatttctaa cgaagccctc
    66901 agcccaagtg aaaatgaagt cttggctggt attcttgact cttcacgtga tttggaaaga
    66961 attggagatc attctgagtc tttaggcatt ctaattgaag gcatcatatc taaacaaatt
    67021 ggtttttcaa tatctgctcg tcaagaattg acagagatgt atcaattgac gcattgttta
    67081 acactggatg ccattagagc tatcgttgat agtgatacag acttggcgca aactattgtg
    67141 actcgccata aagaaattga agaaaaagag cgacgattac gtaaaaccca cattaagcgc
    67201 ttgaattgtg gagaatgtac ggcacaagca ggtattaatt ttattgatat tatttcccac
    67261 tatacccgca tcacagatca tgccttgaat ttagcagaga aagtactttc acaccagctt
    67321 taaaaaagag aaaacgtgaa tgatcatcca cgttttcttt tttgaatcca aaaagtggta
    67381 tataccattt acaaagtaaa gaataaggcg tataataagg aaaaaaggga ggaaaaaaga
    67441 tgacatgcta tcttaaagca gattgttttt attacccaac agaggtgaaa ccggctggct
    67501 acctaggtct tcatgatggt gtttttgggg agtggacaga aattgttccg gcagatgcgc
    67561 aaatcattga ctacaccggt tatcaaattg caccaggtct tgtggatacg catatccatg
    67621 gctatgcggg agctgatgtc atggataatt ctgcccaagg gattcatcaa atgagtgaag
    67681 gactattagc aacaggagta acgtcttttt taccgacgac cttaacttct acctttgagc
    67741 agttagaaaa agtatcaggg actattgctt cagttgctga tcaggtaaaa ggtgctaaaa
    67801 tacaaggtat ctactttgaa ggtccttatt ttaccgaaga atataagggt gctcaaaacc
    67861 caagttatat gaaaacccca cgcttggagg aatttgatgc ttggcaaaaa gctgctaaag
    67921 ggctcatcaa aaaaattgcc cttgctcctg agcgtgaggg tgtcaaagaa tttgtgtctg
    67981 cagtgacaaa acaaggcgta acagtggcct tagggcattc aaatggtact tatcaagagg
    68041 ctaaagaagc tgttcaagct ggtgctagtg tttgggttca tgcttataat ggcatgcgag
    68101 gattgaccca ccgtgaacca ggaatggtgg gagcggttta taatcttcca aatacttacg
    68161 cagagttgat ttgtgatggc caccatgtct caccaattgc ttgtgatatt ttgatgcagc
    68221 aaaaagggca tgatcatgta gccatgatta cggactgtat gcgagcaggt ggttcaccag
    68281 atggtgatta cctcttgggg gaattctctg tggttgtggc aaatggcact gctcgtctta
    68341 aagagagtgg aaacttggca ggatctattt tgaaattaaa agacggcctt agaaatgtag
    68401 tggcctgggg aatcgcaact ccggcagaag ccattcatat ggcaacttat gtgccagctg
    68461 tttctgtcgg tattgacgac gtatgtggtc aaatcaaagc tgggcatgcg gctgacttta
    68521 ttgttcttga taaggattta acacttgttg caacctattt aaatgggcaa aaagcttttg
    68581 atgcctaaga gatacaaaag gattggagta gctatgtctg gcaggccaat tctttttgta
    68641 ttttctttct ttatgataga atagattaaa gtaatcgctt acagatattg ataaaaggag
    68701 gtttttgtga tggtaacaac agtaaaaatg acaagtggct atgagattcc cgttttagga
    68761 tttggaactt accaagcagc cgatggtgag gaagcttacc aatctacctt agcagccatc
    68821 aaggctggct atcgtcatat tgatactgca gctatttata aaaatgaaga aagtgtgggt
    68881 cgtgccatca aggattctgg ggttctacga gaagacttat ttattacaac taaactctgg
    68941 aatgacgccc atagttatga aggggcaaaa gacgctttag ctgcttctct tgaccgtctt
    69001 ggtctggatt atgtggatct ctatcttatc cattggccaa acccaaaagc tctgcgtaac
    69061 acttggaaag aggcaaatgc ccaagcatgg caatatatgg aagaggcggt tgaagcaggg
    69121 cttattaaaa gcattggcgt cagcaatttt atggtgcatc atctagaagc tcttcaagag
    69181 acagctaaaa taactccagc aattaatcag attcgattag ccccaggttg ctatcaaaag
    69241 gaagtggttg attattgtaa ggcaaatgag attttattgg aagcttggag tcctctagga
    69301 caaggagaga tttttgataa tgagactatg cagcagttag ctaataaata tgacaaaaca
    69361 gtggcacaag ttgccttagc ttggtcgctg gcagaaggtt ttattccctt gccaaaatcg
    69421 gtgcatgatg agcgcatcaa ggaaaatatg gctatttttg atgtgagctt gacacaagaa
    69481 gataaaaaaa caattcgcta tctctcagga atgtcagcga ttcctaaccc tgatactaca
    69541 agtttttaag gaactacaaa gatttagcca taattcgcta aatctttttt gaaaacggtt
    69601 tgacaaaggt ttatcattta gctataatct ttattagtgt tttgtgaaag aaactattat
    69661 tgaaaataag gagccgtatt gtgaccatct ttttagtgat gttagctatg tttactattc
    69721 gtttagtatt tttgaagaaa tcgataacaa atgaaaaagc catattagcc caaggaggac
    69781 aggaatttgg tgctcagaac acgaaatttt tgacgttact tcacattatg atttatgtgt
    69841 ttgcggtgat tgaagcgctg cttaaacaaa ttaagtttga tggcattagt tttttaggtc
    69901 ttttgttgat gttattatca gtagctgttt tatatgaagt gacacgtatc ttaggtgaca
    69961 tttggactgt aaaattgatg ttagcaaaag accacaaata tgtggatcac tggttgttca
    70021 aaacgattaa acatcctaac tactttttaa atatcgcccc tgagctggtg ggcatagcct
    70081 tactttgcca tgctaaaatt acggctatgc ttcttttccc atgctacatt gtagtaatat
    70141 atttacgtat tcgagaagaa aacaagctat tagcggaagt gattattcca aacggtactc
    70201 gaacaaaacc ttaagctcat gatggacaaa ctaatggctt tatgctaaac tagactctag
    70261 gaaaaaggat gcaagtatct tatctaaagc gagttcgggg tagttagagc cgaatggtag
    70321 gactgcagat tggcgcttcc gtttgggcag tgtgattaag tatatttgtc aatattgccc
    70381 aaaaagatac tatataaatg aagtaataaa ttagggtgga accgcgtttt gacgccccta
    70441 ggtcttatga tttaggagca tcaaaatgcg gttttttggt gcctagacct gtaatacatg
    70501 ctagtaacat cgtcaggtat tttactgatg acaaaaaaac gattgtcaat gatataccat
    70561 tttactacta tcaaaggagt acgaaatgtc taaaaaactt acctttcaag aaatcatctt
    70621 gaccttacaa caatattgga atgatcaggg ttgtatgctc atgcaagcct atgacaatga
    70681 aaaaggagct gggaccatga gtccttacac gttcttacgt gctataggtc ctgagccatg
    70741 gaatgcggct tatgtagagc catcacgtcg tcctgcagat ggccgttacg gagaaaaccc
    70801 aaatcgtctt taccaacacc accaatttca agtggtcatg aaaccatcac catcaaatat
    70861 tcaagaactt taccttgctt ctttggaaaa attgggcatc aatcctttag aacatgatat
    70921 tcgttttgtt gaagataact gggaaaaccc atcaacagga tcagcagggc ttggttggga
    70981 agtttggctt gatggaatgg aaatcacaca atttacgtat ttccaacaag ttggtggcct
    71041 tgcgacatct ccagtgacag cagaagtaac ttatggtctt gagcgcttag cttcctatat
    71101 tcaagaagtg gattcggtct atgatattga gtgggcacca ggtgttaaat atggtgaaat
    71161 cttcttacaa cctgagtatg agcattcaaa atattccttc gaaatatcag accaagacat
    71221 gctgcttgaa aactttgaaa agtttgaaaa agaagcctcg cgtgccctag aagaaggttt
    71281 ggttcaccca gcttatgatt acgtgctcaa atgttctcat acgtttaacc tgctggatgc
    71341 ccgtggcgct gtttccgtca cagaacgcgc aggctacatt gctcgtatcc gtaatttggc
    71401 acgtgtcgtt gctaagacct ttgttgcaga acgcaagaag cttggatttc cactgttgga
    71461 tgaagcaaca cgcgcaatct tgctagctga agatgacgaa taagtcgatt taaagatgat
    71521 ctagttgcga gctttgtaat cttaagagcg agcaagaagt gggcgaccga aggtcgccga
    71581 gtcaaggtta ctcccgctgt agtgacaatt cggtaaggtt acttatcgaa cgagggagtt
    71641 ggcgagactt taggctggct aactaggaat ggaacacttt tgttttctga aattatccac
    71701 tggataattt cactttgcgt cccccctacc taagggaaca atcaaaaaga tactttttag
    71761 agaaaggaac tgaacatggg ctacggacta tgtcaaaaag accaagactt cctaggtgca
    71821 agcacctgcg tcgctttgct attttgatgg tgtccgctta acgcccttgg tatcttaatt
    71881 atgagtaaaa atctactaat cgaacttggt ctggaagaac ttccagccta cgtggtcaca
    71941 ccaagtgaaa aacaactggg agagcgcttg gcgactttct taacagaaaa tcgtctctct
    72001 tttgaagata tacaaacctt ttcaactcca cgccgtttgg cagtgcgtgt gtctggatta
    72061 gctgatcagc aaacggattt gactgaggac tttaaagggc ctgctaagaa aattgccctt
    72121 gatgctgatg ggaatttctc aaaagctgct caaggatttg ttcgtggcaa aggcttgacc
    72181 acagatgcta tcgaattccg cgaagtcaaa ggagaagaat acgtttatgt gaccaaacac
    72241 gaagctggaa aacctgctaa ggaagtgctt ctaggcgtta ctgaagtgtt gtcagcaatg
    72301 accttcccag tcagcatgca ctgggctaac aatagttttg aatatattcg tcctgttcac
    72361 accttgacag ttctgttgaa tgatgaggcc ttggaacttg acttcttgga tattcattct
    72421 ggacgcgtca gccgtggtca ccgtttttta ggtactgaaa ccactatcac aagtgctgat
    72481 tcttatgagg ctgatttgcg cagccaatgc gtcattgttg acgctaaaga gcgtcaagag
    72541 atgattgtgg agcaaatcaa gacgcttgaa gtggagcagg gtgtgcaagt tgacattgac
    72601 gaagacttgc ttaatgaagt tttgaacttg gtcgagtttc caacagcttt catgggaaat
    72661 tttgaggcta aataccttga tgtcccagaa gaagtattgg taacatcaat gaaaaaccac
    72721 caacgttatt ttgtggtacg tgatcaggct ggtcacttga tgccaaactt tgtatcagtt
    72781 cgtaatggga atgatcaagc cattgaaaat gttattaaag ggaacgaaaa agttttggta
    72841 gctcgcttag aagatggtga attcttctgg cgtgaggatc agaaattgca aattgctgat
    72901 ttagttgcca aattgaccaa tgtgaccttc catgaaaaaa tcggctctct tgctgaacac
    72961 atggatcgta cgcgtgtcat tgccgcatca cttgctaagg aagccaacct atctgctgag
    73021 gaagtcacag ctgttgaccg tgctgcccaa atttacaaat ttgacctttt aacaggtatg
    73081 gttggtgaat ttgatgagct gcaagggatt atgggtgaaa aatatgctct tctagctggt
    73141 gaagatgctg ctgtggcaac agcaatccgt gaacactact tacctgatgc tgcaggaggt
    73201 gcgctacctg aaaccaaagt tggcgctgtc ctggccttgg cagataaatt ggatactctc
    73261 ttgtcattct tttctgttgg attgattcca tctggctcta atgatcctta tgctctacgt
    73321 cgtgcaacgc agggtatcgt tcgtattctt gatcattttg gatggcgcat cccaatggat
    73381 aagctggtag atagcttata tgacttgtcc tttgatagtt tgacctatac caataaggcg
    73441 gatgtgatga actttatccg tgctcgtgtg gataagatga tgggcaaagc cgcaccaaaa
    73501 gacattcggg aagctattct agcaagttca acctttgtgg ttccagaaat gttagcggta
    73561 gctgaagctc ttgtcaaagc cagccatacg gaaaattaca aaccagcagt tgaatctttg
    73621 tcacgtgctt ttaatttggc agaaaaagcg gacgcttctg ttcaggtgga ccctagcctc
    73681 tttgaaaatg agcaagaaaa cactttgttt gcagctattc aaggcttaac tctagcaggc
    73741 agtgctgccc agcagttaga acaggtcttt gcccttagcc cagtgattaa tgatttcttt
    73801 gataatacaa tggttatggc agaagatcaa gcccttaaga acaaccgtgt agctatttta
    73861 tcagatttag taagcaaagc taagaccatt gctgctttta accaactaaa caccaagtaa
    73921 atagaaagga aagagccgtt ggggacttag ctagaaaagt gagttcagta cccgagtgga
    73981 aagaacaagg cctttaaaca ttgcttttca cagtgagagt caagtcagtt ttttaagtct
    74041 tacacttttt tcccaggctc ttagtggctt aacatggatc ctaaaaaaat tgctcgtatc
    74101 aatgagctgg ctaaaaagaa aaaaacggta ggcttgactg gacctgaaaa agtggaacag
    74161 gcaaaactcc gtgaagaata cattgaaggc tatcgtcgct ctgtcagaca ccatatcgaa
    74221 ggcatcaaat tggtggacga agaaggaaac gacgtgaccc ctgaaaaatt aagacaggtg
    74281 caacgtgaaa aaggcttgca cggccgttca ttagatgacc caaaatcata agacaaaaag
    74341 cagctctgaa ctgctttttg tttatcgtga tgactgttag cttttatttt aaatggtatg
    74401 atacttcaaa gtgaccacac gtttttatat tgtatagtca aaatattggg aaaaaccatg
    74461 tgtttgagtt ataatagaag aaatcaaaga aagaaggtag tacttatgac aattaaaaaa
    74521 ttctctctac tagccatagc cagcctctct ttactcagtc ttgcagcctg tgatatggat
    74581 gataaagacg atcatatgga taatcaacca aagacaagtc aaactagcaa gaaagttaaa
    74641 ctttcagaag acaaagccaa atcaattgcg ttaaaagatg cttctgttac ggaagctgat
    74701 gctcaaatgc tatcagttac acaagataat gaagatggca aagccgtgta tgaaatcgag
    74761 tttcaaaaca aagatcaaga atacagctat accattgacg ccaactcagg ggatattgtg
    74821 gaaaaatctt ctgaaccaat caatgactaa tcaagaactg taatgaataa gacagcctta
    74881 actcttgtgt ccaattgtct ttgcctctta ggcgcggctg tttgataccg tgttgccttt
    74941 gaggcttagt tctctttatg acccaatgat gactctggat tagcagagtg attgttgggt
    75001 cttttgattt tctttgataa gaaagattac ctcgttagaa atgaggagac gtggttgtca
    75061 tcagtggatt tttcaagatc atctagtggg ataagctacc tatcttatca gctttttttt
    75121 agctttaaaa attcttgata atatatttct gataaaatta gctataatag aatcaaatag
    75181 gaaaacgctt acttaaagga gggtaatgaa tgtcgcaaga aaagtatatc atggctattg
    75241 atcagggaac aacaagttca cgagcgatta ttttcaatca aaaaggggaa aaggttagca
    75301 gtagccaaaa agaattccct cagattttcc cacacgctgg ttgggtagag cacaatgcta
    75361 atcagatttg gaattcggtt cagtctgtta ttgcgggtgc ttttattgag tccagcatca
    75421 aaccaagcca aattgaagca atcggaatta ccaaccaacg tgagaccaca gtggtttggg
    75481 acaaaaaaac gggtgtacct atttataatg ctattgtgtg gcaatcacga cagacggcac
    75541 caattgctga gcaactcaaa caagatggcc atacaaaaat gatccatgaa aagacaggcc
    75601 ttgttattga tgcctacttt tctgcaacca agatccgttg gattttagat catgttcctg
    75661 gtgctcaaga acgagctgaa aaaggcgagt tactttttgg aaccattgat acttggctgg
    75721 tttggaaatt gacagatggt gctgttcatg tgacggatta ttccaatgcg gctcgtacca
    75781 tgctctataa tattaaagac ttaacatggg atgatgagat tttagagctt ttaaatattc
    75841 caaaagatat gcttccagag gttaaatcca attctgaaat ttatggcaaa acagctgcct
    75901 ttcattttta tgggggcgaa gtgcctattt caggtatggc gggtgaccaa caggcagctt
    75961 tgtttggcca actagctttt gagcctggta tggtgaaaaa tacttatgga accggttctt
    76021 tcatcatcat gaatactggt gatgagatgc agctatcgag taataacctt ttgaccacca
    76081 ttggttacgg gattaatggg aaggttcact atgctttaga aggctctatt tttattgcag
    76141 gctctgccat tcaatggttg cgagatggtc ttaaaatgat tgagacctca ccagagtctg
    76201 aacagctggc actagcatct accagtgatg atgaagtcta cgttgtgcct gcctttaccg
    76261 gtttaggagc tccttactgg gattctaatg cgcgtggatc tgtctttggc ttgacacgtg
    76321 gtaccagcaa agaagacttt gtcaaagcaa ccttacaatc tatcgcctat caagtgcgag
    76381 atgttattga taccatgcag gtggattcag gtattgacat tcaacagctc cgtgtggatg
    76441 gcggtgcagc catgaataat atgctcatgc aatttcaggc tgatatttta ggaattgata
    76501 ttgcccgtgc taaaaattta gaaacaacag ctctaggagc agctttctta gcaggacttg
    76561 ctgtgggcta ctgggaagac atggatgctt tgaaagagtt aaatgccaca ggccagctct
    76621 ttaaggctag catgaatgaa tcgcgcaaag aaaaattata caagggttgg aagcgcgctg
    76681 ttaaagcaac tcaagttttc acccaagaag aagatgcaga tgacgatgca aaataactag
    76741 aggaggatgg aatggaattt tcaagagaaa caagacgctt agctctccaa aaaatgcaag
    76801 aaagagattt agacctactg attattgggg gaggtattac gggtgctggt gtggcacttc
    76861 aggcggcagc tagtggccta gatacgggtc tgattgagat gcaagatttt gcgcaaggaa
    76921 cctctagccg ttcaaccaaa ttggttcacg gggggcttcg ttacttgaaa caatttgatg
    76981 tggaggtggt ttcagatacg gtgtcagagc gggctgtggt gcaacaaatt gcaccccaca
    77041 ttccaaaacc agaccctatg ttattacctg tttatgacga acctggtagt acctttagca
    77101 tgttccgttt gaaggtcgct atggatttgt atgatctttt agcaggcgtg tccaatacgc
    77161 cagcggccaa caaggtgtta accaaagaag aagtcttaaa acgagaacca gacttaaaac
    77221 aagaaggctt gcttggtggt ggggtttacc ttgatttccg taataatgac gcaaggcttg
    77281 ttattgaaaa tatcaaacga gctaatcgtg atggggctct tattgctagt catgtgaaag
    77341 cagaagattt cttgctagat gacaatggta agattattgg tgtgaaggcg cgtgatttgc
    77401 tgtcagatca agaaatcatt atcaaggcta aattagtcat caacaccaca ggtccatgga
    77461 gtgatgagac tcgtcaattc tctcataagg gacaaccgat tcatcaaatg cgccctacaa
    77521 aaggggtgca tctggtagtg gaccgtcaaa aattaccagt gtctcaacct gtctatgttg
    77581 acacagggtt aaatgatggt cgtatggtct ttgtcttgcc acgtgaagaa aaaacttatt
    77641 ttggaacaac ggacacggac tacactggag acttggagca cccacaagtt actcaagaag
    77701 atgtggatta tttgttaggc gttgtcaata accgctttcc aaatgccaac gtgaccattg
    77761 atgatattga aagcagttgg gctggtcttc gccccttgtt atcaggtaat agtgcttctg
    77821 actacaatgg tggcaacagc ggtaaagtca gtgatgatag ttttgatcac ttggttgata
    77881 ctgtcaaagc ctatattaac cacgaagata gccgagaagc tgttgaaaaa gctattaagc
    77941 aggttgaaac cagcacatct gaaaaagaat tggatccgtc tgcagtgtca cgaggttcaa
    78001 gttttgaccg tgatgagaat ggactcttta ccttggcagg tggtaagatt accgactatc
    78061 gcaaaatggc tgaaggagca ttgacaggga ttattcaaat cctcaaagaa gagtttggca
    78121 aatccttcaa gcttatcaat tcaaaaacct atcctgtttc aggaggtgaa atcaatccag
    78181 ccaatgtaga ttcagaaata gaagcttatg ctcaattagg aacacttagt ggtctttcga
    78241 tggatgatgc taggtatttg gcaaaccttt atggttctaa tgcgccaaaa gtctttgcct
    78301 taactcgtca attaacagca gctgaagggt taagtttagc tgaaaccttg tccttacatt
    78361 atgcgatgga ttatgaaatg gctcttaaac cgacagatta tttcttgaga agaacaaatc
    78421 acctcttatt tatgcgagat agcctagatg ctttgattga cccagtgatt aatgaaatgg
    78481 ctaaacattt tgaatggtct gatcaggaaa gagtggcaca agaagacgat cttcgtcgcg
    78541 tgattgcaga caatgatttg agtgccctaa aaggccagca ggagggttaa tatggatatc
    78601 tttggtgaat ttttgggtac agccttattg gttttactag gaaatggtgt ggtagcaggg
    78661 gttgtcttac ccaaaacgaa aacccatgct tctggctgga tcgtgattgc gactggctgg
    78721 ggaattgcag ttgctgtggc agtttttatc agtggcaaag ttgcccctgc ccacctcaat
    78781 ccagctgtta gccttgcttt tgccatgagt ggaaccattg cttggtcaac agctattgcc
    78841 tatagccttg cccaactatt gggagctatg gttggttcaa ctctggtatt ccttcagttc
    78901 aggccacatt atctggctgc tgagagtcag gctgatattt tagggacatt tgcgacaggt
    78961 cctgctattc gagataccag ctcaaaccta ttgagtgaaa tctttgggac ctttgtcttg
    79021 atgcttggta ttttggcatt tggcttatat gatatgccag caggactagg aaccctctgt
    79081 gtaggtacct tggttattgg gattgggtta tccttaggag gaacgacagg ttacgccatt
    79141 aacccagcgc gtgatttagg acctcgtcta gttcatgcta ttctaccact caacaacaag
    79201 ggagattctg attggtctta tgcttggata cctgttgtag gaccaattat tggagcggcc
    79261 ttagcagttt tgcttttcca agtcatgtcc taaccatcac taaaggggtt ggctatcata
    79321 ggccagctcc tttgcttttt ctttatagga ttaggtaaaa cgctttcata tcttaaaaac
    79381 aactgctata ataatactat tatgacatta acgacaaaga ccatacatgt tatcggggca
    79441 tcctttgctg gtctagcctt tgttgataaa tataaggacc tcaatccaga ttcccaaatc
    79501 attctcattg ataaggaaag ctgtcccaat tatattccaa atggtatcaa ccaattattc
    79561 agaggagaca ttcaagacct gtctgatgct atgtggggaa gggcctgcct agcagcacaa
    79621 atagaatcta accaccggtt tattcaagca gaagtgttag ctatcgaagc tccctcaaac
    79681 accttgcttc tcaaagacag tcaaggacga gtttttgaag aaggttatga aacgcttgtt
    79741 tgtgccatgg gtgctagccc ccagtctcat tatattgaga cgtcacagac caacaaagtt
    79801 ttggtaacca aatattatga agaaagccaa gctagtttaa aactgattga ggctagccaa
    79861 gaggtcttgg ttattggtgc cggcttgatt ggcttagacc ttgcctacag tttgtcctta
    79921 caaggcaaac gggtcaaact gattgaagca gccgaacgtc cagatttcta tcagactgac
    79981 gcagaactga tagcccctgt aatggcagaa atgtccactc accatgtcac ctttattaat
    80041 aataagcgtg ttacggctat ccatgagata gagggaaaag ttgtcgctca taccgagcaa
    80101 ggggacacct tccaaggtga tttggctatt ttagccatta actttaggcc aaatacacac
    80161 cttttgcaag gacaagtggc ttgtgctctg gataagacca ttttggtcaa tgaaaactta
    80221 cagaccagcc aggctaatat ctatgccatt ggagacatgg tttcattgta ttttggtata
    80281 ttgggaatgg attactatac acctttgatt aaccaagcaa tgaagacagg tcaggctctg
    80341 gctctgcatt tagctggata tcctattcct ccattacaga cggtcaaggt attaggaagt
    80401 tctcactttg gttattatcg cgcgagtgtt ggtgtgacag aagaagaagc agagctttat
    80461 atggatacgt gtagctattt gtaccaaaat ggggattcta aaaacctctt ttggctgaaa
    80521 ttaatagcta gaaaaacgga tgggatttta ataggcgctc agctcctatc caaaaccaat
    80581 gctcttgtca tcgccaatca attaggtcag gctctggctc tgaaagttac agacggtgac
    80641 ttagcatttc aagattttct ctttttacaa ggtcacagtg atttggctta tcatcttcat
    80701 gaagcttgtc tcaaattatt tgaaaagagg ctccgccatg aagattgaag acttaatgga
    80761 taaagaacga aaagctcaat atcgtctctt ggtgaccctt tatcatgcta aagaaacgtt
    80821 aaggctaaaa gacctaatga ggctatcaaa cttgtctaaa gtgaccctat taaaatacat
    80881 tgacaaccta aatcatttgt gtcgagaaca aggtttagcc tgtcaattac ttttagaaaa
    80941 agacagtctg agcttaaaag aaaatggcca gttccattgg gaggatttgg tagctctgct
    81001 tctcaaagaa tcggttgcct atcagatatt gacctacatg tactgccatg aacactttaa
    81061 catcaccaac ttatccgttg aactgatggt tagtgaagct actctaaaca gacaactagc
    81121 tcacctcaac cagcttttat cagaatttga tctggcgctc tcgcaaggca gacaactggg
    81181 aagtgagctt cagtggcgtt atttctattt ggaattgttc cgtcatacct tgaccagaca
    81241 aggcatagac gccttggtca atcagttaga cgcttcgcat ttggctacct taattgagcg
    81301 gctgattggc cagtcattat cggcagaagc cttagaacaa ttattgattt ggttggcgat
    81361 ttcgcaagcg cgaatgtcct ttcaaaaagg ctacaatgat cattttttaa gagatagtga
    81421 ctttatgaca tctaatattt tctttaagcg cttagaaagc atgcttttac attacttaag
    81481 acgctatgcc cttgaatttg atgcttttga agctaagagc ctctttgtct ttttgcatgc
    81541 ttatcctcta cttcctattg ccagcatgaa gtatagtttg ggttttggag gtcctattgc
    81601 tgatcacatt tcagaagcct tatggctttt aaagaaggct catgtgatta tccatcagac
    81661 aaaggaggaa atcatttatg gcttggggat atttttttcc aaagcttact tttttaaagg
    81721 agctatcctt agccaaccaa ccaatagcca atacctttat caattagtag gcgaagataa
    81781 aagagcgctt ttaagggtta tcataaacca tttagtgctg caaatgggtc aggaaacgga
    81841 tttcagtcag cagttgagtg acgacatttt agcattgttg gttttttcca ttgagcgcca
    81901 ccatgagcct cttttagtag ggcttgcctt ggggcaaaat aaggtggaag cagccattgc
    81961 ggaattggcc attagacgtc atttggggca tcgtagggat tttcaattaa tgccctatga
    82021 tcatcaaaaa gtttatgact gtctgattac ctatcagact gtctatttac cgagacaaga
    82081 tttaccctat taccggttaa aacagtatag ctccccctat gaactcactg ccttagaagc
    82141 ttttctcaaa gaccttttcc agcaaaaaaa tacacgagaa gaggaactct cactcagccc
    82201 agcagctaag tctagttttg cacacaaaac tgtgtgatac ttggtctttt ctaaggactg
    82261 ttacactttt ataataataa agtaggatag tctaaaggta gatgatttga aaaagcttat
    82321 caaatagagc ttaacaaaat cgaaaatttt tggaggtaag aaatgaaatt tttcctagat
    82381 acagctaatg tagccgctat taaagcgatt aatgaacttg gcgttgtaga tggtgtcacc
    82441 accaatccaa ccattatctc acgtgaagga cgtgattttg aaacagttat caaagaaatc
    82501 tgtgacatcg tcgatggccc aatcagtgct gaagtgacag ggttaacagc agatgctatg
    82561 gtagaagaag ctagaagcat tgctaagtgg catgacaatg tcgtcgttaa aattccaatg
    82621 accacagaag ggttaaaagc aacaaacatt ctttcaaaag aagggattaa aactaatgtg
    82681 accttgattt tcacagtaag ccaaggttta atggcaatga aagcaggcgc aacttacatt
    82741 agcccattta tcggtcgttt ggaagatatt ggcacagatg cttatcaatt aatcagcgac
    82801 cttcgtgaaa tcattgactt gtacgatttc caagcagaaa tcatcgcagc aagtattcgt
    82861 acaacagccc atgtggaagc tgttgctaaa ttaggcgcac acattgcgac gattccagac
    82921 cccttgtttg ctaagatgac gcaacatccc ttaacgacaa atggtttgaa aacctttatg
    82981 gaagattggg cttcctttaa aaaataaggc taaagagtct gtggctactg tgtcaacagg
    83041 ctctcttata ttcatcgtcc aaaagaattc accaatgatg tccaaactag tttttttctg
    83101 gcaaaataga gaaaaagaat ttagggactt tggaggattt tctgaaaaaa gcgtctattt
    83161 ttgtgataca atagacaata gaaaacgttt aattttagtt gtaataaaca gagaggtttt
    83221 acttatgaca tttgatgcaa ttgaccagtt ggcagtaaac actgtccgca ccctatcaat
    83281 ggatgccatt caagcggcaa attctggaca cccaggactt ccaatggggg cagcacctat
    83341 ggcctatgtt ctttggaatc acttcatgaa catcaatccc aaaacaagcc gtaattggtc
    83401 aaacagagac cgttttatcc tatcagcagg tcatggaagt gccatgcttt atagcttgtt
    83461 acacttagct ggttatgatt tatctgtaga agatttaaag aacttccgtc aatggggttc
    83521 taaaacacca ggtcacccag aagtgaatca cacagacggt gtcgaagcaa ccacaggacc
    83581 tcttggtcaa gggatcgcaa atgccgttgg tatggccatg gcagaagctc acctagcagc
    83641 taaatttaac aaaccaggct ttgacatcgt taatcactac acctttgctt tgaatggtga
    83701 cggtgacctt atggaagggg tcagccaaga agcagcaagt atggcaggac atttaaaact
    83761 tgggaaattg gtcttgctat atgattcaaa cgacatctct cttgatggtc caacctctat
    83821 ggctttcaca gaagatgtga aaggacgttt cgaagcttac ggttggcaac atatccttgt
    83881 gaaagatgga aatgatttag aagaaattgc agctgctatt gaagcagcta aagctgaaac
    83941 tgagaaacca accatcatcg aagtcaaaac cattattggt tttggtgccg aaaaacaagg
    84001 aacttcagct gttcacggcg ctcctcttgg agcagaaggc attgcttttg ccaaaaaagc
    84061 ttaccaatgg actcatcaag attttgaagt gcctgctgaa gtaacagagc gctttgctca
    84121 aggtcttcaa gcgcgtggtg aaaaagcaga acaagcctgg aatgacttgt ttgcagttta
    84181 tgaagcagaa tatccagaat tagcagcaga ataccaaaaa gcctttacta acgaagctgc
    84241 tcaagtagaa cttgaagcgc acgaacttgg tagttcaatg gcgagtcgtg tatccagtca
    84301 acaagccatc caacaaatct cagaacaagt agcctctttc tggggtggat cagcagatct
    84361 ttcagcatct aacaacacaa tggttaaggc tgaaacagat ttccaaccag gtcactacga
    84421 aggccgtaac atctggtttg gcgttcgtga atttgccatg gctgcagcca tgaacggtat
    84481 tgcccttcac ggcgggacac gcgtttacgg cggaaccttt tttgtcttct ctaactatct
    84541 tcttccagct gttcgtatgg cagcgctcca aaacttgcca acagtttatg tcatgacaca
    84601 tgattctatc gctgttggtg aagatgggcc aacgcacgaa ccaattgaac aattggcaag
    84661 tgttcgctca atgcctaact ttaacgttat tcgtccagca gacggtaacg aaacaaatgc
    84721 tgcttggaaa cgtgccattg ctgaaacaga tcgcccaacc atgcttgtat tgacgcgtca
    84781 aaaccttcca gtgcttgagg gcacaaaaga attggcagaa gatggtctta acaaaggagc
    84841 ttacatcttg tcagaagcca aaggcgacct tgaaggtatc ttgattgcaa caggttcaga
    84901 agtgaaactg gcaatggata ctcaagaagc tcttgaagca gaaggcattc atgtgcgtgt
    84961 cgtatctatg ccatcacaaa atatctttga cgaacagtca gcagagtata aagaaagcat
    85021 cctaccagca gctgtgacta aacgtctcgc tatcgaagca ggttcaagct ttggctgggc
    85081 aaaatatgtt ggcctagcag gaaaaacatt gaccattgac acttggggtg cttcagctcc
    85141 aggaaatcgt atcttcgaag aatatggttt cactgtggca aatgcaactg agttatacaa
    85201 atcactctag gttacacatc ccaaacagag taaatcaaat gatttactct gtttttttaa
    85261 aataaaataa ccagttcttt cttttcctca aactgcctaa tacacttctt ttgataagaa
    85321 gtcattgaca aaacgattca taaaaattat aatttaattg ttattgtatt agcgtaaaag
    85381 tacaaaaaat aaaggagtat aaatggaaaa gaaacgacag cgcttatacg atgtgattag
    85441 acaggcttat gattatccag aaaaccgtga aaatgtggcc ttgtcgcagc tacttttagc
    85501 agcttctaat agattaatta aacacagtaa cccacttctt gttgcctacc aactaaacca
    85561 agatgtggat aattacttac ttgataatga cattttactt ccaaaatcgc tttgccgttt
    85621 taagcagtca ttggaaaagt atattttaga ggaagcctca tcagtctagg gagaaaaaga
    85681 gaagaaaagg aaaaaggata ccatgataga atttaaacat gtttcaaagt tgtatggcga
    85741 caaagaagct ctcagcgatt taaacgtcac catcaatgac ggtgaaattt ttggccttat
    85801 cggacataat ggtgcaggta aaaccacgac catcagcatt ttgacttcta ttatcgaagc
    85861 gagttatggc gaagtatttg tggatggtca acttctgaca gaaaatagag aagctatcaa
    85921 aaaacaaatt gcttatgtgc cagattctcc tgatattttc ttgaatctaa ctccaaatga
    85981 gtattggcag tttttagcta aaatttatgg ggtgtcagat gaggaccgag aagaacggtt
    86041 agcacagctg acaacacttt ttgaactgaa ggaagaagtt aatcaaacca ttgatagttt
    86101 ctcacatggg atgcgccaaa aagtgattgt gattggtgct cttgtatcaa atcctaacat
    86161 ctggattttg gatgaaccat taacaggttt ggatcctcag gcttcttttg accttaagga
    86221 aatgatgaaa gctcatgcag cttctggaca tacggtctta ttttcgactc acgtgctatc
    86281 agtcgctgag cagttatgtg atcgtatcgg gattctaaaa aaagggaaat tgatttttgt
    86341 tggaacgatt gatgagttga aagaacacca tcctgacaaa gacttggaga gcatctacct
    86401 tgaactcgca ggtcgtaagg cgcaagaaga ggggtgatgg gatgaattgg tctactattt
    86461 gggaacttat caagataaac attctttatt ccaatccaca aagtttagct aacctcaaaa
    86521 agcgtcagga aaaccacccg aaagaaaact tcaaagccta taaaagcatg atgaggcaac
    86581 aggccttaat gattgccatg tttttggtga tttacctttt tatgtttatt ggtgtcgatt
    86641 tcagtcatta tccaggactt ttctcctttg acgttgctat gttttttatc atgtcaacct
    86701 tgacagcctt tagctctctt tacaccattt tttatgaaag taatgactta aaactttata
    86761 ttcacttacc agtaacgtca gaagaactct atattgcaaa aattgtctcg tcgctaggga
    86821 tgggtgctgt ctttttgatg cctcttatct ctcttctctt aattgcctat tggcaactat
    86881 tgggaaatcc tttgtctatt ttagtagcta ttgtgctctt tttagtgtta ctagtgagtt
    86941 cgatggtatt agctatttat atcaatgctt gggtgggcaa aatcattgta aggagtcgca
    87001 agcggaaact catttcaact atcatgatgt ttgtctcaac ttttggagct ttcgtcttaa
    87061 tttttgcgat taatattagt aacaacaagc gtacgatgac ggatggcgta tttactgatt
    87121 acccaactat tccgtatttc aaaggattct atgatgttat tcaggcaccg ttttctactg
    87181 cggccctcct taacttttgg ttgccattgc tactgatttt agctatggta tatggtattg
    87241 tcacaaaagt gatgccaact tattatcgtg aggcttttta tattagtaac gagaacaaag
    87301 ccaagcaaac taaaaaacca gttaatcgtc ctcatcagaa tcaatcactg acgcagttgt
    87361 tgcgaaaaca tcatctttta acgttacaaa atgcaacttt actgacacaa acctatctca
    87421 tgcccctgat gtatgtgatg ctttttatcg gtccaagttt gtcacgtggc acaggtttct
    87481 ttaagcatat ttccccagat tactttgggg tggccttatt atttggggtc agtttgggtg
    87541 tcatgtgtgc aacaccaacc agctttattg gagtaggtat ttcacttgaa aaggataact
    87601 ttacctttat taaaagctta ccaataacgt taaaaaaatt cttgctggat aaattttgct
    87661 tgctcgtcgg tctgcaactg attgtgccta tggtgattta tcttgtgttt ggtctctttg
    87721 tgttgcacct gcatcctctt ctaacgattg ctttttgtct tggctacgcc ctgtctctga
    87781 ttgtgcaagg ggaattgatg tatcgtcgtg actaccggct tctggattta aaatggcaag
    87841 acatgacaca actctttacc agaggaaatg ggcagtggct aacaatgggc cttatctttg
    87901 gtaatttaat agtcacaggt gtagtaggtt ttggagctgt tatcattgcc aatattatcc
    87961 aacaacctct gttgattagt attctattga gttgtctgac actaatggtt ttagggattg
    88021 ctcacttatg gattcaaaaa accttctgga aaagcttaga gaagctttaa cgaagagaga
    88081 tcattattcg gaaaaacagt cctctggggc tgtttttatg ctataatttg ggtatgatga
    88141 aacgacaatt tgaagatgta acacgtatcg taattaaaat tggcactagt tcattagtgc
    88201 taccaacagg taaaatcaat ttagaaaaaa tcgaccaact ggcttttgtg atttcaagtt
    88261 tgatgaataa gggcaaggaa gttattttag tatcatcggg agcgatggga tttggactag
    88321 atattttgaa aatggaaaaa cgtccgacca atcttgctaa acaacaggca gtttccagtg
    88381 ttggtcaggt ggccatgatg agtctttatt cacaaatttt tgcacactac caaaccaacg
    88441 tgtcacaaat tttattgacg agagatgtgg tggttttccc agaaagtcta gccaatgtta
    88501 ccaatgcttt tgaaagtctg attagtttgg gcattgtgcc gattgttaat gaaaacgatg
    88561 cggttagtgt ggatgaaatg gatcatgcga ctaaatttgg agataatgac cgtttatctg
    88621 ctgttgttgc tggtattaca aaagctgatt tattaatcat gttgtctgat attgatggcc
    88681 tttttgataa aaaccctact atttatgagg atgcgcagtt acgcagtcat gttgcagtca
    88741 ttacgcaaga aatcattgcg tcagcaggtg gtgcgggcag taaatttggc acaggtggga
    88801 tgcttagcaa aattcagtct gctcagatgg tatttgaaaa caaaggacag atggtcttga
    88861 tgaatggagc taatcccaga gatattttaa gagtgcttga agggcaacca ctaggcacct
    88921 ggttcaagca gatagaagag gtaacacatg actgatatga gaaggttagg gcaaagggca
    88981 aaacaagcta gtcttttaat agcacctttg tcgacgcaaa ttaaaaatcg ctttttaagc
    89041 accttagcaa aggcattagt tgacgataca cagactctct tagccgctaa ccaaaaagat
    89101 ttagcgaatg ctaaagaaca tggtatttct gacatcatga tggatcgctt gcgcttaact
    89161 tcagaacgga ttaaagcgat agcacaggga gttcaacagg ttgctgactt agctgatcca
    89221 atcggacaag tcattaaggg ctatactaac ctcgatggcc ttaaaatcct ccaaaagaga
    89281 gttcctctag gggtgattgc gatgattttt gagagtcgcc cgaatgtttc agtggatgct
    89341 tttagtctgg cgttcaaaac caataatgcc atcatcctaa ggggaggaaa agatgccctt
    89401 cactcaaata aagctttggt gaagttgatc cgacaaagtc tggaaaaatc agggatcacc
    89461 ccagatgctg tccagctagt tgaggatccc tcacatgctg ttgctgaaga attgatgcag
    89521 gcaacggact atgtggatgt gttgattcca cgtggtggtg ctaaattaat tcagaccgtt
    89581 aaggaaaaag caaaagtgcc tgtcatcgaa acaggtgtgg ggaatgtgca tatctatgtg
    89641 gatgctcaag ctgacttaga tatggctact aatattgtta tcaacgctaa aacaaagcgc
    89701 ccaagtgttt gcaatgcagc tgagggattg gtaattcacg aagctgtagc agcaaggttt
    89761 attcctatgc ttgaaaaagc gatcaatcag gttcagccag tagaatggcg ggcagatgac
    89821 aaggctttgc cgttatttga gcaggcagtg cctgcaaaag cagaggattt tgagaccgaa
    89881 tttttagatt atatcatgtc tgttaaggtt gtttcctctt tggaagaagc tatttcttgg
    89941 ataaatcagc atactagtca ccattccgaa gctatcatca caagggatat taaggcagca
    90001 gagacctttc aagatttagt ggatgctgct gctgtttatg tcaatgcttc aacacgattt
    90061 accgatggtt ttgtttttgg gcttggtgct gaaattggga tttctactca aaaaatgcac
    90121 gcccgtgggc caatgggctt agaagccttg accagcacta aattttatat taatggggat
    90181 ggacatatca gagaataagc tactagaagg tcccttaatg actaatgaaa gagaaaaaga
    90241 agaagcaaag gttgctttag aagaactttt acatcagatt caggtgattc atttggaatt
    90301 gaaaattgtc cgaaattggg gctattttga tctttttgga gacggtatgc ttgtcagctg
    90361 gatcaaacgt cgaaaaatga gcaaggtcaa ccaattatta atagacttac aagttactct
    90421 tcaaaactgc cgaagatagc tggcagacgt cgataggcta ttattagctg acttaccgaa
    90481 tatgagttgg gataaaatct ttgatatttg gttagacaac ctgctgacag attgttgtgt
    90541 gattaaagaa gctaaaaatt ttttacaagt agttgaaatt ctagaggcag cggctaagtc
    90601 agtgcttgct aagttggctg atagcgaaca aaaagaacaa gattagagaa gaggaagatt
    90661 cccacgagaa tgaaatcctt ttctcttact ttttcatttc taaacctttt gaagtatggt
    90721 acaattaaag ttatgacaaa agaatttcat cacgtgaccg tactccttca cgaaacagtg
    90781 gacatgcttg acataaagcc tgatgggatt tatgttgatg cgacgctagg tggctcaggc
    90841 cactcagctt atttgttgtc caaacttggt gaagaagggc acctctattg ttttgaccaa
    90901 gaccaaaagg ctattgacaa tgcacaagtt accctcaaat cttatattga caaaggacag
    90961 gtaactttta ttaaagataa ttttagacac ctcaaagcac gtttaacagc gcttggagtt
    91021 gatgaaattg atggtatctt atacgacctt ggtgtttcca gcccgcaatt ggatgaaaga
    91081 gaacgagggt tttcttataa acaagatgct ccattggata tgcgcatgga tcgtcagtcg
    91141 ctcttaacag cttacgaagt ggtgaatacc tatccattca atgatttggt taagattttc
    91201 ttcaaatatg gtgaagataa attctccaag cagattgctc gaaaaattga acaagcaaga
    91261 gctattaagc ctattgagac aacaacagag ttggcagaat tgattaaggc agcaaagcca
    91321 gctaaagagt tgaagaaaaa aggccaccct gctaaacaga tttttcaagc tattcgcatt
    91381 gaagtcaatg atgaattggg agcggccgat gaatctattc aggacgctat ggaattatta
    91441 gcccttgatg gtcgtatctc agtcattacc ttccattctc tggaagatcg cctaaccaag
    91501 cagttgttta aagaagctag tacggtggat gtgccaaaag ggcttcctct aattcctgaa
    91561 gatatgaaac ctaagtttga acttgtttca cgtaagccga tcttacctag tcattcagag
    91621 ttaacagcta ataaaagggc acactcagcc aagctacgtg ttgccaaaaa aattcggaaa
    91681 taagcctatg acaaatgaaa aaagaactca ggcagttaca aatgccttgc aaaaacgaat
    91741 aaaaactttc tctagaattg agaaggcttt ttatactgct atcattgtaa cagcgattac
    91801 gatggcagta agtattattt acctgcaaag tcgtaagttg cagttacaac aagaaatcac
    91861 tagtttaaat agtcatattt cggatcaaaa actagagctt aataatgcca agcaagaagt
    91921 aaatgagtta tctcgccgtg atcgtattat agatattgct ggtaaagcag gcttaagcaa
    91981 ccgtaataat aatatcaaga aagtcgagta atctatgaaa aaatggcaaa aatatgtttt
    92041 agattatgtt gtgcgcgata ggagaactcc agtcgaaaat cgcgttcgag ttggacaaaa
    92101 tatgatgctc ttaactatct ttattttctt tattttcatt attaatttca tgattattat
    92161 tggaacagat caaaagtttg gagttagttt gtcagaaggg gcgaagaagg tttatcaaga
    92221 aaccgttacg atccaagcta agcgtgggac catttatgat cgaaatggta cagctattgc
    92281 agtggattct acgacttata gcatatacgc aattttggat aaatcatttg tctcggcttc
    92341 agatgaaaag ttatatgtac aaccttctca gtatgaaaca gtagctgata ttttaaaaaa
    92401 gcatctggga atgaaaaaaa cagatgtaat taaacagctt aagcgtaaag gacttttcca
    92461 agtctcgttt ggaccgtcag ggtctggcat ttcatatagt actatgtcta ctattcaaaa
    92521 ggctatggaa gatgccaaaa tcaagggaat tgctttcaca actagtcctg gtcgtatgta
    92581 tccaaacggg acatttgctt cagaatttat aggcttggca tctctaacag aagataaaaa
    92641 gacaggtgtt aagagtttag ttggaaaaac aggtctagaa gcttcttttg ataaaatttt
    92701 atcaggtcaa gatggtgtta ttacttatca aaaagatcga aatgggacca cactcttggg
    92761 tacaggtaag actgtcaaga aagctattga tggcaaagat atttacacaa cgctatctga
    92821 gcctatccag accttcttag aaacccagat ggatgttttt caagccaaat caaatggtca
    92881 gttggccagt gcaacacttg ttaatgctaa aactggtgaa attttggcaa caacacaacg
    92941 ccctacttat aatgctgata ctctgaaagg acttgaaaat acgaactaca aatggtacag
    93001 tgcacttcat caaggaaatt ttgagccagg ctcaaccatg aaagtgatga ctctggcagc
    93061 ggctattgat gataaagttt tcaacccaaa cgaaaccttt agcaatgcta atggtttaac
    93121 aattgcagat gctactattc aagactggtc tattaatgaa ggcatttcca caggacagta
    93181 catgaattat gcacaaggat ttgccttctc aagtaacgtt gggatgacta aacttgaaca
    93241 aaaaatgggt aatgcaaaat ggatgaatta tttgacgaag ttccgctttg gttttcctac
    93301 tcgttttggt ttaaaagatg aagacgcagg tatatttcct tctgataata tcgtgactca
    93361 agctatgagc gcttttggtc aagggatttc tgtaacccag attcaaatgc ttagagcctt
    93421 tactgctatt tctaataatg gtgagatgtt agagccacaa tttatcagtc aaatttatga
    93481 tcctaacaca gcaagtttta gaacggcaaa taaagaaatt gttggaaaac ctgtatcaaa
    93541 aaaagccgct agtgaaacaa gacaatacat gattggtgta ggaacagacc ctgagtttgg
    93601 aacactctat tcaaaaacat ttggaccaat tattaaagtg ggtgatttac ctgttgctgt
    93661 taaatcagga acagcacaaa ttggttcaga agatggaagt ggttatcaag atggtggatt
    93721 gactaactat gtctattcgg ttgtggcaat ggtgccagct gataaaccag actttttgat
    93781 gtatgttact atgactaaac cacaacattt tggtcccctt ttttggcaag atgtggttaa
    93841 cccagtattg gaagaagcat acttaatgca agatacacta actaagccag tagtatcaga
    93901 tgctaatcgt caaacaactt ataaattacc aaactttgta ggaaagaatc ctggtgagac
    93961 atcaagcgag ttgcgtcgaa atcttgtcca gccagttgtc cttggtactg gcagcaagat
    94021 caaaaaagta tcgcatcagc ccggtcaaac gttaacagaa aaccaacaag ttctcatatt
    94081 atcagaccgt tttgtggagg taccagacat gtatggctgg acaaaatcca atgttaaaac
    94141 ctttgctaaa tggactggaa tagacatcag ctttaaagga acagattctg gtcgtgttat
    94201 gaaacaaagt gttgatgttg gtaagtcctt gaaaaaaata aaaaaaatga ccattacttt
    94261 aggagattaa catgttttta acccttattg cagcaatcat atcctttatg gtatctgctt
    94321 tcacaatgcc ttattttatc aaattctatc aattgaaaaa aattggtggg caacaaatgc
    94381 atgaagatgt caagcaacat ttagctaaag ctggaacacc gactatgggg ggaactgttt
    94441 ttcttttagt agctacggca gtatcgttat tggttagtct attttcgatc aaaaacactc
    94501 aaagtttagc tttgatttca ggcattttat caattgttgt catttacggg attatcggat
    94561 ttttggatga ttttttaaaa atttttaaac aaatcaatga aggattgaca gccaaacaaa
    94621 agttagcctt gcagttggtt ggaggattga tgttctattt tttacatgtt agtccaagtg
    94681 gcatttcctc tattaatgtg tttggttatc agctgccgct gggaattttc tacctattct
    94741 ttgttttgtt ttgggtggtt ggtttttcaa atgccgttaa tttgacagat ggtatcgatg
    94801 gcttagcttc tatctcagtg gtgattagtc tagtgactta cggcgttatt gcctacgttc
    94861 agagtcaatt tgatgttttg ttactgattg gagcaatgat tggagccttg cttggcttct
    94921 tctgctttaa tcacaaacct gctaaagtat ttatgggaga tgtaggtagt ttagcccttg
    94981 gagctatgtt ggctgccatt tctattgcgc ttcgtcaaga atggactctc ctgattattg
    95041 ggatcgttta tgttcttgaa acaagttctg tgatgttgca agtgtcctat ttcaagtaca
    95101 ccaagaaaaa atatggagaa ggtcgtcgta tttttagaat gacgcctttc caccaccatt
    95161 tggaattggg aggcttgtct ggtaaaggca agaagtggtc agaatggcag gtagatgctt
    95221 ttttgtgggg agtaggaagt ctagctagtt tactagtttt agctatctta tacgtgttct
    95281 aagggggatt atcaagaata gtcaccaata gcattttgat taacatcatc aataagagag
    95341 tggagatgac ccacaaatgc tgattttgtg agtgttgtcc cactcctttt gcttgtctct
    95401 aacaataatg atataatatg gaagaaaacg aggtaaaaca tgtcatttaa agattatcat
    95461 tttaagcaat acgttcagca agcgctggaa gaaattggct ttgtcaatcc aacagaggtc
    95521 cagaagcggc tgattcctat tgttaactcc ggtcgtgact tagttgggga atcaaaaaca
    95581 ggttcaggga aaacccacac ctttttgttg cccatttttg aaaaacttga tgaagctaaa
    95641 gcagaagtgc aagtcgttat tacagcacct agccgtgaat tagcaactca aatttttgat
    95701 gcttgtaaac agattgctaa gcacttccaa gaagagattc gtttggccaa ctatgttgga
    95761 ggcacagaca aactccgtca gattgaaaaa ctaaaaggca gccagccgca tattgtcatc
    95821 ggaaccccag gtcgtattta tgacttggtc aagtctggtg atttagcgat tcataaagca
    95881 acgacctttg ttgtggatga ggccgatatg accatggaca tgggcttttt ggatacggta
    95941 gataagattg cagcttcgct tccaaaatct gttcagattt tggtgttctc agcaactatt
    96001 ccacagaaat tacaaccctt tttgaaaaaa tacttgacca atcctgttat tgaacaaatc
    96061 aagacaaaga ccgttatcgc agataccatt gataactggc ttgtgtcgac aaaagggcgt
    96121 gataagaatg gtcaactgtt agagattctc aaaaccatgc agccttatat ggctatgctt
    96181 tttgtcaata ccaaggaacg cgcagatgat ttgcatgcct ttttaacagc taatggctta
    96241 aaagtggcta agattcatgg gggcattcct ccaagagaac gtaagcgcat catgaaccaa
    96301 gtcaaaaaac tggactttga atacattgtt gccacagact tagcagcgcg tgggattgac
    96361 attgaagggg tcagccatgt gatcaatgac gccatcccac aagacttgtc tttctttgtc
    96421 catcgtgtag gccgaacagg tcgaaatggt atggcaggaa ctgccattac actttaccag
    96481 ccaagtgacg actcagatat caaagagctg gaaaaaatgg ggattgcctt tacaccgaag
    96541 gtgctcaaaa atggagaatt tcaagatacc tatgaccgtg atcgccgtca aaaccgtgaa
    96601 aaagcctatc aaaaattaga cacagaaatg attggtttgg tcaaaaagaa aaagaaaaaa
    96661 gtcaaaccag gttacaagaa aaaaattcag tgggcggttg atgaaaaacg tcgcaaagaa
    96721 cgtcgtgctg aaaatcgtgc taagggccgc gctgagcgta acgccaaaaa acaacatttt
    96781 taagaacaaa gagcaagcaa gtgatcaatt ggcatctaat cttgcttttt ttacacctgc
    96841 tacttgtatt gtttaccatt tgttaacaca aaaagtgatc atagcttttg cttattgcta
    96901 taatacggat ttactatttt acatgtgggt ctaagagtgt tagaatatta agacaaacaa
    96961 atacaaaggg gaaatacatg acatcagtgt ttttaaccag tggttgggct ttttatgatt
    97021 acctcatctc accgattcca catggaaaac tttttagttg gcatgctgtt tttgatgcca
    97081 ttccaaatat tatccaacgg cttccaatta cgcttggttt gacactatca ggagcaacct
    97141 ttggcttggt tttggctttg atttttgccc ttgtcaaaat taataaagtg aagctactat
    97201 accctattca agctattttt gtgagtttct tgcgaggaac tcctattttg gtacagttga
    97261 tgttgaccta ctacggtatt cccctctttc taaaatttct caatcagaag tatggctttg
    97321 attggaatgt taatgcaatt ccggcttcta tttttgccat tacagccttt gcttttaatg
    97381 aagcagccta cgctagtgaa actattcggg cagccatttt atcagtagat acaggtgaaa
    97441 ttgaagcagc aaaaagtcta ggcatgactt ctgtgcaggt ttaccgtcgt gtcattattc
    97501 ctaatgcaac tgttgtggct attccaacct tgattaatgg gttaattggc ttaactaaag
    97561 gaacatcgct tgcctttaat gcagggattg tcgaaatgtt tgcccaggct caaattctag
    97621 gcggatcaga ttaccgttat tttgaacgtt atatctctgt tgctcttgtc tattggtcta
    97681 tcagtatttt gatggagcaa gtaggtcgct tgattgaaaa caagatggcc atcaaagcac
    97741 cagaacaagc tagaaatgaa aagttaggag aattgcgttg atgattacaa ttagaaattt
    97801 gagcaagaca ttctcagggc aaaaagtttt agatagtttg gctcttgata ttgaaaaagg
    97861 tcaagtgatt gctttagttg gtgcttcagg agcagggaaa tcgaccttcc ttcgtagcct
    97921 aaactatttg gaaaaaccag attcaggatc cattagcatt ggtgacttta cggttgattt
    97981 tgagaccatt accacagagc aagtccttat tttacgtcgg aaacttgcca tggtttttca
    98041 acaatttaat ctttttgagc gtcgtacagc ccttgagaat gtcaaagaag gtcttaaggt
    98101 ggtcaaaaaa ctgtctgacc aagaagcgac taagctggcg caagcagaat tggctaaggt
    98161 tggtttagca gatcgaaaac atcattaccc acgtcattta tcagggggac aaaaacaacg
    98221 ggtagcttta gcaagagctc tggctatgaa accagatgtt ttattactag atgagccgac
    98281 ctcggctctt gacccggaat tagttggcga agtggaaaag tctattactg atgctgctaa
    98341 atccggacag accatggttt tagtgagtca tgacatgaat tttgtttacc aagtggcaga
    98401 tagagtactc tttttagatc aagggaaaat cttggaacaa ggaacacctg aagaagtctt
    98461 tagacatcct caaaaagaac gaaccaaaga attttttgca agctattcaa aaacatacat
    98521 ttaatgatat tcttttgtta taataaaaag gtctaggtat tcctgggctt ttcttgttat
    98581 gttttttaga aaaacttatg ggaaagaaat aatgactagg tggaaatatg ttagtagaaa
    98641 tctttagcct ttatgtaaaa ggtctcattc tctcaagcct tactatgatt ttaatttgtt
    98701 taatatggac tttatggcga gcaaaaacca aaagagataa aacattgatt gaaagacaag
    98761 cttttcttta tgagatgcta atggttgcta ttttaaccat cccaatttta tcgtttgctt
    98821 ttatgagtat tttggttgtc ataaaatcct aatcattgca agaagggatt atcattgcta
    98881 aaatattggc aagagtagat taaaggagaa aaatcatgta cgatacatta attattggtt
    98941 caggaccagc aggaatgact gccgctttat acgctgctag aagtaattta tctgttgcca
    99001 ttattgaaca aggggcacct ggtggtcaga tgaacaacac ttttgatata gagaattacc
    99061 cgggatatga tcatatatct ggaccagaat tagctatgaa aatgtacgaa cctttagaga
    99121 agtttaacgt tgaaaacatt tatggtattg ttcaaaaaat agaaaatttt ggtgactata
    99181 agtgtgtgtt gactgaagat gctagttatg aagctaaaac ggttattatt gcaacgggag
    99241 ctaaataccg tgtactaggt gttccaggtg aagaatacta tactagtcga ggagtttctt
    99301 attgtgcagt atgtgatggt gcgtttttcc gtgaccagga tcttttggtc gttggtggtg
    99361 gtgactcagc agttgaagaa gctatttatc ttactcagtt tgctaaaaag gtaaccgttg
    99421 ttcatcgccg tgatcaacta agagctcaaa aaatactgca agatcgtgct tttgccaatg
    99481 ataaggtcga ctttatctgg gattcagtcg tcaaagaaat tcaaggcaat gatattaagg
    99541 tctccaatgt cctaatcgaa aatgtgaaaa caggccaagt cactgaccac gcttttggag
    99601 gtgtgtttat ctatgttggt atgaatcctg tgacaggtat ggtaaaggat ctagaaatta
    99661 ccgatcaaga aggttggatt atcacagatg atcatatgag gacaagtatt cctggtattt
    99721 ttgcgattgg agatgttcgt caaaaagacc ttcgccaaat cacgacagct gttggagatg
    99781 gtgcaattgc agggcaaggt gtttatcact accttgaaag tttcccttca taaggttaaa
    99841 actccttcat ttttccttgt ctttccctta aaaaagctaa attgcataag acctttaaga
    99901 aatataaaga acagttttcc ttaatatctt tcctagataa atgttgaaaa ttttctgaaa
    99961 aaaggatata ataaatagta ttttagtgaa tggagtttag aatgtctata aaagaacaaa
   100021 cagacaataa cgaactagaa aatggaatgg taaggggctt agaaaatcgt catgtgcagt
   100081 taattgcgat tgcaggaacg attggaacag gtctcttttt aggggcagga cgctctattg
   100141 ccctaacagg accatctatt atttttgtgt atatgattac aggtgccttc atgtttatga
   100201 tgatgcgtgc catcggtgaa atgctctatt atgatccaga tcaacacacc tttatcaatt
   100261 ttatttccaa atacattggt ccaggctggg gttatttttc gggtctatcc tattggattt
   100321 cccttatttt tattggaatg gcagaaatca cagcagtagg tgcttatgtg caattttggt
   100381 tcccaagctg gccagcctgg ttgattcagt tggttttctt agtcttactt agttcgatca
   100441 acttaattgc tgtgcgcgtt tttggggaaa cagagttttg gtttgccatg attaagattt
   100501 tagctatttt agctttgatt gcaacagcta ttttcatggt attgacaggt tttgaaactc
   100561 acacaggcca tgctagcctt tccaatattt ttgaccatct ttccatgttc ccaaatggga
   100621 aactaaagtt ctttatggcc ttccaaatgg ttttctttgc ttatcaagct atcgaatttg
   100681 tgggaattac cacttctgag acggctaacc caagaaaagt tctaccaaag gctattcaag
   100741 aaattccaac ccgtattgtg atcttttatg tgggagcctt ggtctctatt atggcaattg
   100801 tgccatggca tcagttacca gttgatgaat ctccttttgt gatggtgttc aaattgattg
   100861 gtattaaatg ggcagcagcc ttgattaact ttgtggtctt gacatcagca gcgtcagcgc
   100921 ttaactcaac cctttattca accggtcgtc atctctatca gattgctaat gagactccaa
   100981 acgctttgac caatcgctta aagattaata ctttatctcg acaaggggtg ccaagtcgtg
   101041 ccattattgc ttcagcggtt gtggttggta tctcagcttt gattaatatc ctaccaggag
   101101 ttgcagatgc gttctcactc attacggcct cctcatcagg tgtatatatt gctatctacg
   101161 ccttaaccat gattgctcac tggaagtacc gtcaatctaa ggactttatg gcagatggtt
   101221 atttgatgcc aaaatataaa gtgacaacgc ctttgaccct tgctttcttt gcttttgtct
   101281 ttatctctct tttcttacaa gaatccacct atatcggcgc cattggagca acgatttgga
   101341 ttattgtttt tgggatttat agcaatgtca aatttaaata ataattagcg atatagaact
   101401 gaatccatta actctttctt atttgaggat gtcatgatgg atcagttctt tttttacttt
   101461 agcgataact caagttattt ctaaacccta gccaaagagt cctttttaaa atatgttata
   101521 atagtaacaa taattcaaag gagtcccctt tatgtataaa gatgatagtt taactctcca
   101581 tactgatttg tatcagatta atatgatgca agtttatttt gagcagggca ttcataatcg
   101641 tcatgcggtg tttgaagtct atttccgcaa ggaacctttt aacaatggtt atgctgtttt
   101701 tgccggttta cagcgcatgg tggagtatct agagcaattt caattttcag aaacagattt
   101761 ggcttacctt gaagaactgg gttatccagg aaactttttg acctacctta aagagttacg
   101821 attagaattg accatccgtt cagctaaaga aggagatttg gtttttgcta atgagccgat
   101881 tgtgcaagta gaaggccctc taggtcagtg tcagttggtc gaaacagctc ttttaaacat
   101941 tgttaacttc cagaccttga ttgctacaaa ggctgctcgt attcgttctg tgattgagga
   102001 tgaacccctt ttggaatttg gtacccgtcg tgcacaggaa ctagatgctg cgatttgggg
   102061 aacccgcgca gcgatgattg gtggagcaga tgcaacaagt aatgtgagag caggtaaacg
   102121 ctttgatatc cctgtttcag gtacgcatgc tcatgcttta gtgcaagcct atggtaatga
   102181 ttatgatgct ttcatggctt atgctaagac ccataaagat tgtgtatttc ttgttgacac
   102241 ctatgacaca cttaaagtag gtgtgccaac agctatccga gtagccaaag aaatgggtga
   102301 caagattaat tttctaggtg ttcgattgga ctctggtgac ttggcttacc tctcaaaaac
   102361 agtccgtcag cagttagacg acgctggttt taccgaggct aagatctatg cttctaatga
   102421 cctcgatgaa aataccatcc tcaacttaaa aatgcaaaag gccaaaattg atgtttgggg
   102481 tgttgggacc aaactgatca cagcctatga tcagcctgcc ttaggtgctg tttataagat
   102541 tgtctctatt gagcaagaag atggtagcat gcgtgatacg atcaaattat caaataatgc
   102601 agaaaaagta tccacaccag gtaaaaaaca agtttggcgc atcaccagtc gtgaaaaagg
   102661 caaatcagaa ggcgactata tcacgtttac tgatattaat gttaatgaat taactgagat
   102721 tgagatgttc catccgacct atacctatat taagaaaacc gtcagaaatt ttgatgcaat
   102781 tcctctctta gttgatattt ttgtcaaggg agaattagtt taccagctac cgaccttatc
   102841 tgaaatcaag acttatgcta aaaaagaatt tgacaagctt tgggatgaat acaagcgtgt
   102901 cttaaatcct caagactacc cagtagactt ggcacgagat gtgtggcaaa ataagatgac
   102961 cttgattgat aacattcgta aagatactca tggaaagagt gaatgacatg acattacaag
   103021 aagagatcat tcgacaatta ggcgtcaagg ctagcattga tccacaagaa gaaattcgaa
   103081 aaaccgttga ttttttaaaa gcttatttgc gaaagcactc atttttaaaa acttatgtct
   103141 taggcatttc tggaggtcag gattctaccc tcgcaggaaa gctagcccag atggccattg
   103201 cagagttacg ggaggaaaca agtgatcaag cttaccaatt tatagctgtt cgcttgcctt
   103261 acggggttca ggctgatgaa gcagatgcgc aaaaagcctt ggcttttatt gcaccagatc
   103321 agacccttac cattaatatc aaggcagctg tggacggtca agtagaggct ctacaagcag
   103381 caggcgttga gatttctgat tttaacaaag gtaatattaa agcacgtcag cgaatgataa
   103441 gtcaatatgc cattgctggc caaatggctg gtgctgttat tggaacggat catgcggcag
   103501 aaaacatcac tggtttcttt actaaatttg gtgatggtgg agcagatatt cttcccctct
   103561 ttaggcttaa caaacgtcaa ggaaaggctc ttttgaaagt tttaggagca gatgctgctt
   103621 tgtatgaaaa agttccaact gctgatttag aagatcaaaa accaggcttg gctgatgagg
   103681 ttgccctagg ggtgacctat caagacatcg acgactattt ggaagggaag ctgatttcca
   103741 aagcagctca agcaactatt gaaaaatggt ggcataaagg acaacacaag cgtcacctgc
   103801 caatcaccat ttttgatgat ttttggaaat aagaaatgat gttcaaagag taaaaaaaga
   103861 aaacaaaaaa agttaggtta tcctaacttt tttcttgaag aaaatcaaat aaggtctata
   103921 atagaagtaa tcctttagaa tagaatggct ggataataac catcttgcca atattatttc
   103981 aggtgaagct tatcttaata ttttaggagg acaataatgt cagcattaac agagacattt
   104041 acagaacaat tatttgctca ttacgaagcc aatgcaaaat tttcagctat tgagaatgcc
   104101 gttacgcata atggtttgct aaaatcatta gaaacccgtc aaagtgaagt ggacaatgat
   104161 tttgtgtttt ctattgattt aactaaagat aaggtatcta accaaaaggc atctggtcgc
   104221 tgctggatgt ttgctgcctt gaacactttc cgacacaaat taatcacaga gtttaaatta
   104281 gaaaattttg aactgtcaca agcccatact ttcttttggg ataagtatga aaaagctaac
   104341 tggtttatgg agcaggtcat tgctacagct gaccaagaat taaccagtcg taaagttaag
   104401 tttctcttgg atgttccaca acaagatggt ggccagtggg acatggtggt ttccttgttt
   104461 gagaagtatg gagtggtgcc aaaatctgtt tacccagaat caatctcatc aagtaacagt
   104521 cgtgaattaa accagtattt gaataaatta ttgcgccaag atgctcaaat tcttcgtgac
   104581 ctgattgcat caggtgctaa ggcagaccaa gttgaggatc gaaaagcaga gcttcttcag
   104641 gaaattttta acttcttggc catgaccctt ggtttaccac ctcgtcattt tgattttgcc
   104701 taccgtgata aagatgacca ctatcatgtt gagaaaggtt tgacaccgca agcgttttac
   104761 gacaaatttg ttggcttaaa gctttctgat tatgtgtctg ttattaatgc gccaactgct
   104821 gataagcctt atggcaaatc atacactgtt gagatgctag gaaatgtggt cggtagtcgt
   104881 gaggttcgct acctcaacct tgatatgaaa cgtttcaaag aactagctat caagcagatg
   104941 caggctggtg agtccgtttg gtttggctct gatgtgggtc aagtttcaga tcgtcaaaaa
   105001 gggattttgg caactaatac ttacgatttt gaagctagta tggatatcaa tcttagtcaa
   105061 gataaggctg gacgtttgga ttatagtgaa agtttgatga cacatgctat ggttttaaca
   105121 ggtgttgact tagatgaaac aggaaaaccg ttaaaatgga aggttgaaaa ttcatggggt
   105181 gagaaggttg gtgacaaagg ttactttgtt gcttcagatg cttggatgga tgaatatacc
   105241 tatcaaattg ttgtccgtaa agaattctta acagctgacg agttagcggc ttatgaaaaa
   105301 gagccacaag tactagctcc ttgggatcca atgggtgctt tagcacaatg ctaattcctt
   105361 tctttgcgac tgtatgaaat ctaaaggctg gacaaaacga acagcaaacg gattggactc
   105421 cgcataagaa agtgaacatg aaaaaaatta ttatgctaag aaaatgacat atgaaaaaac
   105481 acgtcttcgg tatatggaaa cgtgtttttt catgtttact ctcttatggc attagttgct
   105541 atttataaca attttaaata agtctatttt gttttaggtt aacgtttgaa aaatcagttg
   105601 ctaattccct taacgttgta ccttttcttt aatacgatta aagaattctg ttttttgttt
   105661 tatattgtat gtggtaagtc atttgtgtca tataaaaacg agtcctcaca gaacgtggac
   105721 tcgcttttta tttagattat cacttaaggt agatattaaa agtaactaaa tggatatgta
   105781 ataaaaggta ggtacagaca ataagtagag ttagagatta atgagttgtc tttttatcat
   105841 cggtagatgg atgattgcta ttgttgtctg tattggttga attacttata tcattgctac
   105901 tactagtatc atctgaagtc gtttggctag aagctgttgt cgtgttattg ctgtaaagat
   105961 tgttgtaaac cgaattagta tagtcggtgt tgctcgcata ggttccgctt aagtagagga
   106021 atccaccact gcgataaaga ccatttggca tcgtccaatc ttcactgtaa ccatttgtta
   106081 agtaagtcat catgctacga taaacgtcag atgcaatctc tagacttgat ccgtatactg
   106141 gggtcaagcg gtttttgtaa cctgtccaaa cagccatggc gtagcgctta gtaaagccaa
   106201 caaagttttc gtctggcgct aatgtaccaa cataatctgg ataaaggccg tatttttcac
   106261 caattttagc tagttcctca tcagtgtagt tagaagtccc tgttttacca gcttgcgcaa
   106321 caccaggaat ggcagcagca gtacctgtac cataagtgag aacagttttt aacatatctg
   106381 tcatcatata ggccgtggtt tctttcatgg cacgttttcc tttttcatca aaagttttac
   106441 ttgtaccatc actaaattcc actttattga cataccttgg tttatgataa ataccaccat
   106501 ttgcaaaagc agcgtatgca gcagccattt tttcactact tgcaccatat tttttatctg
   106561 agctactgtt attacttgag atagcgtttg agtagtgcat ttcgggatag ttaataccta
   106621 aactgcttaa gaaagatcga gcatagtcaa gtcctgcggc ttccagtgct cggactgctg
   106681 ggacatttcg cgatagcata atagcagctt ggattgtcat ccatccgtta tatctaaggt
   106741 cccagttaaa caattgggta gtggttccag gccaataata gactgagtca ttagtcgact
   106801 gagcagtaga agtataaaca ccagattcaa tagcaggagc ataggctgtg attggcttca
   106861 tggtagaacc ccagtcacga tcagttaaaa cagcttggtt agtcccaaat gaaacatttt
   106921 catcttgatt acgtccgcca agctgagcaa taacatgacc atttgtcaca tcaacaatcg
   106981 ttgaagcaac ttggaaatct tggtctggat agtaaacata atcaccagaa tgataaatat
   107041 tataaagagt ctgctgcgca tcggggataa tattggtata aacttttaaa ccagcggtaa
   107101 aaatatcttt attcgtttct tttttgactt cttcaataac ttgttttaga taattatcca
   107161 tatattttgg ataagttgag cgctgttgga gtgattgtag accttcagcg acgggagttg
   107221 cgatggcagt ttcatattct gctttcgtca gatgtttttc catgtacatc tgttgcaaca
   107281 cgacgttacg gcgattttga gcagcttcag gatgaaggta aggatcatat tgactaggag
   107341 cttgagggat tccagccaat agggctagtt gggcataaga taaatcctta agatccttgc
   107401 cataataaga cttagcggct gtcagcatac catagttgcc attacccata tatactttgt
   107461 tgatgtaaaa agtcaggatt tcttgtttag tatattttcg ctccatttga agagcaagcc
   107521 aaacttcttg agccttacgt tttaaggttt gatcagattc attagtagaa aaataggcta
   107581 gtttaatgag ttgctgatca agcgttgacc ccccttgagt ggtctgactc gttagattat
   107641 gaaaggcagc accaaaaata cgataaagat ctactccacg atggttaaag aaacgtttat
   107701 cttcaattga ggtaatagca ttaactagat taatagggat actatcagct gttacatttt
   107761 cacgcttttc agaacccaaa tcagcaatca gattgttatt accgtcataa accaagctag
   107821 agtttgttga ttttaactgg gcttctgaca gtttcggagc actgctaatg tagaaggtaa
   107881 acaaaagacc accaataata ataacaagga taataaggct aagaattgca cttaatacat
   107941 actttagcca cttaaggatt tttggatttt taattgtaat caccgcctaa aaaattttgt
   108001 tcaattatgt ttaaataagg gacttgtgga aaggctccaa atgctacctt aaagccattt
   108061 tttctgatat aatcaatggg catcgattta ctgccattat ctatctgata aaatgaaatc
   108121 aaggcttgag caggtaggta gtaagtctcc ttcagtgtgg aaaagtgaag aaggacaaag
   108181 cagattcctt tttgatgtaa aacgcaagcc atatgttcaa tctgatgtaa atggaaattt
   108241 ttcatgggca tagctgtttt ttgcctggtt tcttttgctt caaaatcaac ataatgtcct
   108301 ttataaacgc cgcaatagtc agtcgttgaa gcttgtctaa agtacgcttc aacgattttt
   108361 gcccgactgc gtttagggta atccactttg acaatttgga caggagtagg ttttttgtga
   108421 atgacagcta tttgacgaga taaataataa tcatttgtcg cgttgatagc agcttcaaag
   108481 gacatacctc tattggcgaa gtccacctta ttttgctttg tttgcttttg aacggaactt
   108541 actttttgtc gaataagatt atgaggataa ttaaccattg ttctcctaat attatctagt
   108601 taatgctaaa aatttaagca cttttattat aacatatttt ttgaaaggat aacacctaat
   108661 gactgcgatt ctaattacag gttaccgaag ctttgaaata gggatttttg accataaaga
   108721 cccacgagtt tcaattatta aacaggctat tcgtaaagat ttaataggtt atttggaaaa
   108781 tggtgtggat tggtttatct ttacagggaa cttgggtttt gaacaatggg ctttggaagt
   108841 agctaatgag ctaaaagagg agtatccctt gcagatagct actatattct tgtttgaaac
   108901 gcatggagat aggtggaatg aaaaaaatca agaagtttta agtcagttta gggctgttga
   108961 ctttgtaaaa tattactttc caaattacga acaaccgacg caatttagtc aatattatca
   109021 gtttttatta gaaaagacag aaggggctta tgttttttat gacacagaaa acgagaccaa
   109081 cttaaaatat tttctcaaga aagcaaaaga tatgccgcat tatcagttgc tattgctaac
   109141 ctttgatcgg ctaaatgata tgtcacaaag ctagcattgt atttttaggg gtattggtat
   109201 ttaaatactt gctttttgaa ctatttttct gtatcattaa taataatact gaaatataat
   109261 tttggtaaaa agattgaccg ttcggagagt aaagaatgac aagtattatt tatagtccta
   109321 aagatatttt tgagcaagaa tttaagacta gtatgcgagg gtttgataag aaagaagttg
   109381 atgaatttct tgataatgta attaaagatt atgaaaattt caatgctcaa attgaagctt
   109441 taaaagctga gaacgaagcc ttaaaaaagg ccaagtttca agctagaaat acagtttcag
   109501 cgactgttca acaaccagta ccgcaaccga ctcgtgttgc tcaatcagct actaattttg
   109561 acatcttgaa acgtattagt aaattggaaa aagaggtttt tggtaaacaa attattgagt
   109621 aatgaaaact gtgcaatttt tggataatcg cgtagtattt taatactatg aggaaagtcc
   109681 atgctagcac tggctgtgat gccagtagtg attgtgctag gcgaacacat aagcctaggg
   109741 atgtgcatac acattacggc gaaggaaatg gctaagtcgt ttgatatgcc aaagtacttc
   109801 tgaaagtgcc acagtgacgt agtttttatg gaaacgtaaa aaatggaacg cggtaaaccc
   109861 ctcaagctag caacccaaac tttggtaggg gcatgggata gttggaaacg aacaagctat
   109921 cctgactgtc aacagacggt agacagatga ttatcgaagg aaataattcc tagttatttc
   109981 cggaacaaaa catggcttat agaaaattgc ataataggtt aagctagcac ttgctagctt
   110041 ttatttgatt taaaagaaag agatatatga aagaaacatt tagattagtc gcaactgcag
   110101 ccgcaggttt agaagctgtc gttggtaaag aagtcagagc actaggtttt gattgtcagg
   110161 ttgaaaatgg gaaagtttat tttgaaggtg atgtagaagc gattgttaaa acaaatcttt
   110221 ggttacgtgc agcagatcgt atcaaaatta tcgtaggaca atttcctgct agaacctttg
   110281 aagaattatt ccaaggtgtc tttgccttgg attggggaaa ttatttaccg ctaggagcta
   110341 agtttccaat ctcaaaagcc aagtgtgtca agtcaaagct acacaatgag ccaagtgttc
   110401 aggcgattac caaaaaagct gttgttaaga aactgcaaaa acatttccac aggccagaag
   110461 gagttcctct tcaagaagtt gggtcaacgt ttaacattga ggtatctatt ttaaaagacc
   110521 aagccactat tatgattgac acgacaggat ctagcctatt taaacgaggg taccgcgttc
   110581 aaaagggtgg ggctcctatt aaagaaaata tggcagctgc tatcttggcc ttatctaact
   110641 ggtttccaga taaacctctg gttgatccca cctgtggatc gggaacgttt tgcatcgagg
   110701 cagccctgat tgggatgaat attgctccag gatttaaccg ttcgtttgct tttgaagaat
   110761 ggagctgggt agataaagac atggtgcaac aagttcgtga tgatgccgaa caagaagcta
   110821 attatgaaat cgaattagat atttctggct ttgatatcga tggccgcatg attgagattg
   110881 ctaaaagtaa tgctgaagaa gctggtttat ctgatgtgat tacctttaag caaatgcgtc
   110941 tgcaagactt tcgaacagac aaggttaatg gtgtagtgat atcaaatcct ccttatggag
   111001 aacggttgct tgatgacaaa gcggttgaca tcttgtataa tgaaatggga caaacctttg
   111061 caccattgaa aacatggagc aaatttatcc ttacaagtga tgaacttttt gaactaaaat
   111121 acgggcaaaa agctgataaa aaacgtaaac tttataacgg caccctaaaa gttgatttgt
   111181 accaatttta tggggaaagg gtaaagcgac atctgatata gagaggtagt aagcgtgtca
   111241 gaagaaagca aagaagtcga agtaacaaaa gaatcgcaaa cattggggct taatgaagcc
   111301 aagtcaatga caattggtga agctgtacgc aaacagtcag agataaaagc aggtgttact
   111361 aaggatgata gtattttaga taagtacatt aagcaacacc gtgacgaagt ttcttctcaa
   111421 aagtttgatg ctaagtatac agagcttgat acagctagtt tagataactt tatcaaaaaa
   111481 caaagagaag cattgagtaa agccggtctt gttgatgacg aacctgtgtc tgcggagtct
   111541 gctgagcaag atagcacttt ggttgaagaa gtagctgaag acttagctcc aatggagact
   111601 actgcggtgg taactgggat tccggtggaa gcgacagtcc ctgtgttaga tctagatcca
   111661 tcagagaggg gcattccaga accacagatg accaaggaag agccaaaaag agatcagttt
   111721 ctttctgaag atagccacca tccagccaaa caaaacacga aaaaaggttg gttaatagct
   111781 ttatttctac tattattggc cattcttgca gttgtatttg gttggaacca tttcttgaga
   111841 caagacagtg gtaaaacaac tcaaacagca agtaaacaga caaagacctc tttgcagacc
   111901 gacagtgcta aaaaagcaac gcgcttgaag gctgctgcta aagctttcga aaaacaatat
   111961 ggtacttttt atacagatgc cacaaagagc aaattaaaaa atagtgcctt tgctactttg
   112021 ccagatttag aagctgcctt gaaagctttg gaaggctctg cttactatga taaggcgaaa
   112081 gcaaaagtcg attcccttaa gaaagctatt gctgctatta cagcggttaa cggtaaattt
   112141 gtttccgatg ttgttgtaga tggtgaaaag gtttcggctg aagtcaaggc tgatgctaat
   112201 tttgatgatt tatcaagtgc aaccttgaca acaggaaatg caaatcttga tgctgtcttg
   112261 caggcaagca tcacagaagg tcgtcagcaa ctagccagca aggctgaggc cgctaaagca
   112321 gctaatgagc aagcagccca ggctcaagca gctcaaggac aaagtacatc agtagcacca
   112381 tctggctatg gcttgacaag ttatgaccct gcaagcttac aacggcattt atcacgtgta
   112441 ccttacaatc aagatgttat tgctgacaga gctaacccat cttgggcatt taatccagga
   112501 gttcttgaaa aaattgtagc aacctcacaa gctagaggtt atatttcagg ctaccaatat
   112561 attttagagc cggttaatat tattaatggc aatggttact ataatatgtt taagcctgat
   112621 ggcacttatc tgttctctat taattgtaag acgggttatt ttgtaggaaa tggcaaaggt
   112681 tatgctgatg ctttagatta ctgagaaaat caaaaaaaac tgagataagg caacttgtct
   112741 cagttttttg attaataaag tatgttgtct taaaatctgc agatagactt gttttttgta
   112801 acaagtcaaa taggtcagta ggattgttat gtttgacaac acactagtat cagatgacat
   112861 ggcgactaaa aggatcgtct gaaatccctt gatcaataat caattgagcc cattctttgg
   112921 cggcaaagag gctatgatcc ttatagtttc cacaggattc aagagttgtt ccaggaacat
   112981 cttcccaagt aatcccagtt gcaatttctt ctaggctgga tttaatcacc ttggcaatat
   113041 cagtagaact gtgttttccc cacatgataa ggtgaaaacc tgttcgacag ccaaaaggag
   113101 agcaatcaat catcccatca atgcgttggc ggatgagctt ggcaagtaag tgttcaatgg
   113161 tatgcaaacc ggctgtttca atagaatttt ggttaggctg cactaggcga acatcaaaat
   113221 ttgtaatacg atcgcccttg ggtccaaatt cttcagaaat aagacgaaca taaggggcct
   113281 ttacaatagt atgatctagc tcaaaacttt cgacgataac ttcttttgtc atttcaatct
   113341 cctttgtttt acactttatc ataacacaaa tagtgagaaa gtggctactt gtggaggaga
   113401 aaaggctaag aaaacagatc aaaggctatc ataatgacct gtgcgataaa agtacttaca
   113461 gaaacagtaa taaaggtttc tttaaaagca tttttgtggt taagtcctgt caatgctaag
   113521 aaggtgagaa agacaccact ttggggcaca atggtaaaga tattagaagc aatagtggca
   113581 acacggtgaa tcatttcggg attaaggcct tgatctaaat aatactgggc aaagttaggc
   113641 atgacaattc ctagagcacc ggaagaagag ccggtaatag ctgacataga ggaagtcaac
   113701 acggctaaac taataagagg attaccggga atattcaaaa tgagatctga gaagaatgtg
   113761 aaacctgggg caatcatcac aacggctccg aaggcaactg cagatgctgt cgcaaaaata
   113821 ggtgcaatag agctgctagc tcctaaatta aagacagcaa tcttattagg aataaactgt
   113881 ctaaagagcc agcttgcggt gagaatggca gctaaaagtg ctatgaaaat aatgttcttc
   113941 ttaaaaaaat cgtttccgaa aaggctaccg gttagggcga taataatgag caacaataaa
   114001 ggtaagatac tggcaaggaa atgtgggaga ttttttgttt tcacttgtat ctcattgtca
   114061 aaagcataag tggcataagt ttcacccctt gccatacttt ttgctagaca atatttcata
   114121 taaaagagcc caaaagtcac gcagccaatt gagccaacga tactcggaat ggcggcagca
   114181 gttagtgagg tgtccaagta ttgaatagga ataacatttt gaatggcagg tgttccgggt
   114241 aaaatcgtca tggtaaaagt tgcaataccg agccaaagag gaacttgaat taagttccaa
   114301 gccaagtcca tttttttgaa tagacttcgt gcaagcggca agacagcaaa catgacaaca
   114361 aagaggctga ttcccccgta agttaatata gcactgatta gaaaaatagc aacgagtact
   114421 ttataaggac tatcatgacc aacttttttt aaaatataat ctgcaataga agtggtttca
   114481 ccgcttgttt ccattaattt ggctaagata gaacctaata aaaagatagc aaaataattg
   114541 agaatataag tggagagtgc ccccataaat tggttgggtt cttttccaag taaggttgtg
   114601 gttggatcca tttgattaaa caaaatgacc aagctggtag caagaggcgc agcgatgata
   114661 atgttaactt ctttgacaga caggtaaata ataacaataa cacctatcaa gacccccaga
   114721 gaaccaataa tttccatagt tttatgacct ccttattaga aaataaagag acagatcaca
   114781 agatacagcc tctttatctc tccaaattta ttgagcagtg tagccaccgt ctaagataca
   114841 ggcttgacct gtaacacctt ttgccttatc actggcaagg aaagacacat agtctgcaat
   114901 ttcttgaacg tcaatgaggc gtttttgagg aacaagtggg tatagcactt cttcaagaac
   114961 attttcaagg ggaatacctc ttgttttgga aaggtcttca aactggccac gaaccagtgg
   115021 tgtgtcaaca tatccaggac aaatggcatt gaccgtaatg cctgaatcag cagcttctaa
   115081 ggcagttact ttggtcagac cgatcaagcc gtgcttagct gaattgtagg cggatttgcc
   115141 agcaaaacca atgacaccat tgatagaagc catattaata atacgaccgt gtttttgagc
   115201 tttcattgta ggaaaagcac gtttaatggc aataaatggt gctgtcaaca tgattttaat
   115261 catgaattca aatttttcag ttggaaaatc ttcaatcatg gcaacatgtt gaaggcctgc
   115321 gttgttaacc aaaatatcaa tacgaccata tttttcaaca accgtatcaa tagcagcatt
   115381 gatggcttct tctttggtga catcgcacac aacactaaaa gcgtcatagc cttctttagt
   115441 atagtcagca acaacctgat ccagtttttc ttgattaatg tcagaaaaaa caaccgtttt
   115501 accttctttt aagaaggttt ccccgatttg ttttccaatc ccgcttgcag caccagtgat
   115561 aaatgcaact tctttagtat gtgtcatgat actatcctcg tctttctttt ggttagtctt
   115621 tagtttgttt tatcaattag ggtaacttcg gtaacgtttt gcacgtcttc aaaggtgtaa
   115681 tctgggttaa tttcaagggc gcatagacct tcatcttgat attcaaagac tcccatttca
   115741 gtaatgatta ggttaacaac attttgagca gtgagaggaa gggtgcattt gtctaaaatt
   115801 tttgctttgc ctttattggt atgctccatt gcaacaatga cttttttagc acctaccaat
   115861 aagtccatgg cccctcccat cccaggaacc atttttccag gaatcaggta attagcaatg
   115921 ctagcttctt tatcaacttg taaggcacct aagacggttg cggccacatg gccgcctcga
   115981 ataataccaa aggaagttga gctatcgaag aaagcccctc caggagcaat actaacaggt
   116041 tgcccaccag cattaacaat actaggatcg tagtgatcat ctgttaatcc agtgagaccg
   116101 acaaaaccat tttcggactg cagggtaatg gttacacctt caggaatata gttggctact
   116161 tttgttggca aacctatgcc taagttgacc agtgtattgt gttctaattc ttgtgcaacg
   116221 cgcttagcaa tacgtgtttg aatctcttct tttgaaagaa cagtagctga tgttcccatg
   116281 ttaggctcct ttcactaagt agttaacaaa aatgccagga gtatggacaa aattaggatc
   116341 catttgcccc acgtcaacaa tttctcttgc ttcaacaatg gtggttttcg cattagcagc
   116401 catcacatga ttaaagttat tttcagaacc tgcgtattgc aaattgccat ttttatctgc
   116461 cttgttagca aaaataagtg cgatatcagc tttcaaaggt ttttcaagaa ggtagtcttt
   116521 gccgtcaaca gtaatgactt cttttccttt ggcaacttcg gttcctattc cagtaggtgt
   116581 taagaaaccg cctagcccaa aaccgccact gcggatgcgc tcagctaatg ttccctgagg
   116641 tacaagatca attacagtct cgccctcagt catttgtcgg cccgcttcac ggttgagacc
   116701 gatatgtgat gcaataatag ttgaaaactg tttattggca accatcttac caacgccttt
   116761 gtcaggaaaa ccggcatcgt tacagattaa agtgaggtct ttgacacctt tttccacaag
   116821 tgtatcaatt aatttttctg gtgtgccatt tgtcatgaag ccaccaacca taatggtatc
   116881 accatcttta acgtgagcta ccgcttcttt tattgtgatt tctttacaca ttttttctac
   116941 caactttcac gagactaagt attgtttttc acgataacag cagttccttg tcctccacca
   117001 atgcaaagtg ttgctagtcc tctggttact tggcgttttt tcatttcgtg gattaatgtg
   117061 actagaatgc gagcgccact ggcaccaata ggatgaccta aagcgatggc tcctccatta
   117121 acattcacga tttctgggtt taactttaaa tcttttaaaa ccgccaagga ctgtgctgca
   117181 aatgcttcat tggactccac taagtccaaa tcagaaattg ttaatccagc tttcttaagg
   117241 gctttttgag tggcaggaat tggtccagtt cccatcagtt caggtgcaac acctgcacta
   117301 gcatagcttt caatagtgac taaaggtgtt aaccctaatt caagagcttt ttcttcagtc
   117361 attaacatca ataaggctgc accatcgttt attcctgagg cattcccagc agtaacggtt
   117421 ccttctttag ggaggaaagc aggacgtaat tgctgtaatt tttcaaggct tgtatcaact
   117481 tttgggtatt catctgttgt aacaattaaa gggtctttgc gtcgttgagg cacagagaca
   117541 gggacaattt cgtcagcaaa acgatgattt tctaatgctt tagcagcttt ttcttggctt
   117601 tctaaagcaa attgatcttg ctcttctctt gagatgccat atttctgagc aacgttttca
   117661 gcagtaatac ccatgtggta attgttaaaa gcatctgtta agccatcatg aacaagagta
   117721 tcaatcaatt gactattacc aagacgttga ccaaagcggt gctgagttga gacataagct
   117781 gcttgtgaca tgttttcgac accaccagca ataacgatat cagcgtcacc aagcatgatg
   117841 ctttgcgcag ctaattggat tgctttaagt ccagaaccgc aaaccatatc taatgtgaaa
   117901 gctgttttat cttcaggaat tcctgagtgg actgcaactt gtcttgccac attttgtcct
   117961 aggcctgcat gaaggacgtt tcctaggatg acttcatcaa ccatttcagg ctttacttgc
   118021 gttttatcaa ggattttttt cagtacagtt gttccaagtt caacagcaga gacactttta
   118081 aaggagcctc caaaagctcc gataggagtt cgtaaagctt caacgataac tatgtttttc
   118141 ataaaataaa catcctttca gttttagaaa gcgctttcca tgtctctaag ataacaagaa
   118201 aacgctaaaa ataaaaatat agaattttta taagcatata attttttttg atagagttgg
   118261 caatagcatt taacatctac ttgtgtcata atataggtaa ttataccgga aaaagtaatt
   118321 gataagacaa ggagaatcct atttggatat taaacaaatt cgttatttta tcgcaatcgt
   118381 tgaaaatcat tttaacttga gccaggcggc ggaactgttg tatgtttctc aaccgacgct
   118441 gagtatgatg attaacgatt ttgaaaaaag agaaaatgtt aagctcttca aacgaaaaag
   118501 aggtcgtatt attgggttaa cctatcttgg tgataattat tataaggacg ctcaaaaggt
   118561 tctcagtctc tatgatgaca tgtttttgaa attgcatgat cacagtaaag ggttaaaggg
   118621 aagtatcagt attggtattc ctcctcttat tttatcagtt gttttctcag aagtaatgcc
   118681 aaaactgatt ttagaaaatc cggggattca attcaatgtt aaggagattg gtgcttacca
   118741 actaaaaaat gaactactcg tgggaaatgt tgacgtcgca gtcttgttat ccccaacagg
   118801 catcgctgat aatttggttg agacttatga aatccagaga tcagaattat ctgtatgcct
   118861 gtctccacgc catcgtttag cttccaaaaa agttattcag tgggaagatt taacagatga
   118921 acaacttgcc ctatttgatc ctagtttcat ggttcaccat ttagtgcttg aagcttgcga
   118981 gcgtcaccaa gtcagaccta atattatttt gacgtcctct tcctgggatt ttatgcttaa
   119041 ttctaccaag attaatcaca acgtcttaac tatttgtccc aaacctatta cagaattata
   119101 ccaattcaag gacattaagt gtattctaat ggaacgtccc atttcttggc gtgttgtctt
   119161 aacacgcctc cggaaaaaaa gttattctga aatagaagcc tacatcatgg acgacttgct
   119221 acagtctttt tttaagtagg gttctcaact acttggccca aatgttaatt tttttaaaaa
   119281 tgaattggaa ttgtgtaaac gctcaattta tgataaacta agagatggct ttctattaat
   119341 gaaatctaga atatattgag gtacaaacat ggttaatatt attttattaa ttgtttctgc
   119401 cctcattggt ttaatattag gttatgcact tatttcgatt agactcaagt ctgcgaagga
   119461 agctgcagag ttgactcttt taaacgctga acaagaagct gttgatattc gtggcaaagc
   119521 agaagtagat gctgaacaca tcaaaaaaac agctaaacgt gaaagtaaag caaatcgtaa
   119581 agaattactt ttagaagcaa aagaagaggc aagaaaatat cgtgaagaga ttgaacaaga
   119641 atttaagtct gaaagacaag agcttaaaca actcgagaca cgcttagcgg agcgctcctt
   119701 aactcttgac cgtaaagatg aaaacctatc aagtaaagaa aaggtactag atagtaaaga
   119761 acaaagtctg accgataaat ctaaacacat tgatgagcgg caacttcaag tggaaaaact
   119821 tgaagaggag aaaaaagcag aactggaaaa agttgctgcg atgacgattg cagaagcgcg
   119881 tgaagtgatt ttaatggaga cggaaaacaa actgacccat gaaattgcga cgcgcattcg
   119941 agatgccgaa cgtgacatca aggaccgaac agttaaaaca gccaaggact tgttagcgca
   120001 agccatgcaa cgccttgctg gtgagtatgt gactgaacaa actattacca gtgtccatct
   120061 cccagacgac aacatgaagg gccgaattat tggacgtgaa ggccgtaata ttcgtacttt
   120121 agagagcttg actggcattg acgttattat tgacgatact cctgaagttg ttatcttatc
   120181 aggatttgat cctattcgac gtgaaattgc tcgtatgacc ttggaatctc tgattgctga
   120241 tggtcgcatc catccagctc gtatcgagga attggttgag aaaaatcgtc ttgaaatgga
   120301 taatcgtatt cgtgagtacg gtgaagctgc agcctatgag attggtgcac caaaccttca
   120361 tcctgatttg attaaaatca tgggacgcct gcaattccgt acctcgtttg gtcaaaatgt
   120421 cctacgtcac tctgttgagg ttggtaagtt agctggtatt ttagctggtg aactgggtga
   120481 aaatgttgcc cttgcccgcc gcgctggttt cttgcatgat atgggtaaag ctattgaccg
   120541 tgaggttgaa ggtagtcacg ttgagattgg aatggaattt gcacgtaaat acaaagaaca
   120601 tccagttgtt gtcaacacta ttgctagcca ccacggagat gtggagccag attctgtgat
   120661 cgctgtgcta gtagctgcag cagacgctct cagttcggct cgcccaggcg ctcgtaatga
   120721 gtcaatggag aattacatca agcgtcttcg tgatttagaa gaaatcgcga caagttttga
   120781 tggggtacaa aatagttttg ctctacaagc tggacgtgag attcgtatta tggttcaacc
   120841 tgaaaaaatt tcagatgatc aggttgtcat tttgtcgcat aaagtaagag aaaaaattga
   120901 aaacaatcta gattacccag gaaatattaa agtaactgtt attcgtgaga tgagagcggt
   120961 tgattatgcc aagtagaaaa agaggaatta tcctcttttt ctttatgact tgcctttgaa
   121021 aatgttcttg aaaaagacta gcctttttga taaactatta aaaagcaact aataaggaga
   121081 atataatgtc tgaacgcggt ttgttaatcg tcttttctgg cccttcaggt gtcggaaaag
   121141 gaacggtaag acaagaaatt ttttcaacgc cagatcataa atttgaatat tcggtttcaa
   121201 tgacgactcg tccgcaaaga ccgggcgagg ttgatggggt tgattatttc ttccgcacac
   121261 gtgaagaatt tgaagaactc attaaaactg gtcaaatgct agagtatgct gaatatgttg
   121321 gtaattacta tggcacccct ttaacttatg ttaatgagac tcttgataag ggaattgatg
   121381 tctttttaga aattgaagtt caaggagctc ttcaggttaa gtcaaaagta ccagatggtg
   121441 tttttgtttt tttaacacca ccagatttag atgaattaga agaccgcctg gttggtcgtg
   121501 gtacagatag tcaagaagtc atagctcaac gtattgaaag agcaaaagaa gaaattgccc
   121561 ttatgcgcga atacgattat gcagttgtta atgatgaagt tgccttggca gctgagcggg
   121621 ttaagcgtat cattgagaca gaacactttc gtgtggagcg cgtgattggt cgttatgata
   121681 aaatgattaa aataacaaaa aatcccttta aagctaaata gaaaagagta agcattatga
   121741 tgttaaaacc ttccattgat accttattag ataaagtacc atctaagtat tcacttgtga
   121801 ttttacaagc caaacgtgcc catgaactag aagctggtgc cactccaact caagaattta
   121861 aatcagtgaa gtcaacactt caggcacttg aagaaattga atcaggaaac gttgtgattc
   121921 acccagatcc ttcagctaaa cgtgaagctg tccgtgctaa gattgaggca gaacgcttgg
   121981 ccaaagagga agaggaacgt aaaatcaaag aacaaattgc caaagaaaaa gaagaagaag
   122041 gagaaaaaat ctaaggtttc agaaatctta gattttttca tatttagtac gatgtccatg
   122101 acagaaaagg agaagcaaat ggaaaaagta gctcatgtga ttgtagatat tccattgatg
   122161 caaacggaca agccattttc ttatggtatt ccaaaagagt tagtttctct cgtgcagctt
   122221 ggttctcgtg tgcatgttcc ttttggaaaa gggaatcgtt tgttgcaagg ctttgttatt
   122281 ggttttggcc aggaagattc aagctctctt aaactgattc agaccgtttt agatcctgag
   122341 ccagtcctaa accaagaaca attgaccctt gctgatcagc ttcgaaaaac agttttttct
   122401 tataaaatca cgctcttaaa agcaatgatt cctaatcttc ttaactctaa ctatgataaa
   122461 gtgctaaggc cagagtcagg tctaaaaaag cctgataggg actttctttt tgaaggaaaa
   122521 ccatctgtct tatattctac cttagaccgc gagaaggaaa aaatagctct taagggcata
   122581 caagctgggc atattactgt tagttattta gccaaagaca agaaaaacct aaagacagaa
   122641 aaatattatc acgtcgactt agacgcctta gcggtacatc ccatctctag tcgtgccaaa
   122701 aagcgtcaat tattaaaaga ctatctgcta acccatacga aggaagctaa acttgcaacg
   122761 ctttatcaag ccttttctag agatgtggtg gcttactttg tgacaaatca cttaattcgt
   122821 attgacgaac gtcaaattga tcgcagtgag ccctattttg accagatcaa accatcttct
   122881 tttttaacct taaatgaaca gcaggcatca gctgttactg aaattgttga gcaaattggg
   122941 aaaccgagta aacctttttt gattgaaggt attacaggtt cgggtaagac agaagtttat
   123001 cttcatatca tcgaagcggt tttaaaacag gataagacag ccattgtttt agtaccagaa
   123061 atttcgttga ctcctcagat gacctctcgt tttatttccc gtttcggaaa gcaagtggct
   123121 attatgcatt caggcttatc agatggtgaa aagtttgatg agtggcgcaa gataaaaaca
   123181 ggacaggcta aggttgtggt tggtgcccgc tctgctattt tctctccact agagcggatt
   123241 ggtgcaatta ttattgatga ggagcatgaa tcaacctata aacaagaaag caaccctaga
   123301 taccatgcca gagaggttgc cctgctcaga gctaaacacc atcaagcagt tgtggttatg
   123361 ggctctgcta cgccaagtat tgaaagccga gcaagggcta gtaagggtgt ctatcatttt
   123421 attcaattaa cgaaaagagc aaaccctctt gctaagattc cagaagtaac gattgttgat
   123481 tttcgtgatt atattggaca gcaagcagtt agtaatttta ccccatattt gattgataag
   123541 attaaagaac gtttggttaa aaaagaacaa gttgtcttaa tgttaaatag acgtggttat
   123601 tctagttttg tgatgtgtcg ggactgtggt tatgtggaca aatgtcccaa ctgtgatatc
   123661 tctttaaccc ttcacatgga tactaaaact atgaattgcc attactgtgg gtttcaaaaa
   123721 cctatcccaa ttacttgtcc tgagtgtcat agcaacagta tccgctatta tggcactgga
   123781 actcaaaaag cttttgatga attgcaaggg gttatcccag aagctaggat cttgagaatg
   123841 gatgttgaca ccacacgaaa aaaaagaagt cacaaaacca tactagatag ttttggtcgc
   123901 caggaagcag atattttgtt agggacgcaa atgattgcca aaggactgga ttttccaaat
   123961 gtgactttag ttggggtact aaatgcagat acctccttaa atttgccaga ttttcgagcg
   124021 tcagaaaaaa cgtttcaatt gttaacacag gttgctggtc gggcaggccg tgcccataag
   124081 ccaggggaag tcttgattca aacttataat cccgatcact atgctattca attagctaaa
   124141 caacaagatt ttgaagcctt ttaccgttat gaaatggcga ttcgccgtca gatggcttat
   124201 cccccttact actttacagt gggtattacg ctttcgcatc gtttagaagc atcggttgta
   124261 aaaaaagctt atcaagttac agaactgcta aagagtcact tatcggataa tattaaaata
   124321 ttaggaccga ctcctaagcc aattgctaga acacacaatt tataccacta tcaaattttg
   124381 ttaaaatacc gttttgaaga taacctagaa gagacgctca atcgtattct tgattggagt
   124441 caagaagcag ataatcgtca tttaaaacta attattgatt gtgaaccgca acaattttta
   124501 taaggtaaat cactaaatct aggatgatca gttatgatat aataaaaata caaagaggaa
   124561 agtcatgata aaattattat ttatgggaac tccccaattt tcagcaactg tattgaaggg
   124621 cttgctagat aatcctgcct atgagatttt aggagtggtt actcagcctg atcgagctgt
   124681 tggacgcaaa aaagatatta aggtaacacc tgtaaagcaa ttagctcttg agcatggaat
   124741 atcaatctat cagccggaaa aattatcagg ctctcaagaa ctcattgaga ttatggaact
   124801 tggtgcagat ggtattatta cagcagcatt tggccaattt ttaccaacaa tattacttga
   124861 ttcagtttca tttgctatta atgtacatgc atcattgtta cctaaatatc gaggtggagc
   124921 acctatccat tatgctatta tgaatggaga taaagaggct ggcgttacta ttatggaaat
   124981 gataaaagaa atggatgcag gtgacatggt cgctaaagca agcactccaa ttcttgaaac
   125041 cgataatgta ggtactcttt ttgagaaatt agccatcatt ggtcgagact tacttttgga
   125101 tagtttgcca gcttatcttt ctggagaatt aaaacctatt cctcaagatc acagccaagc
   125161 tactttttcc cctaatatct ctccagaaca agaaaaatta gattggacaa tgtctgatca
   125221 agaagtgttc aatcatattc gaggtatgaa cccttggccg gtagcgcata cgtttttaga
   125281 ggggcaacgt ttaaaaattt acgaagctca attagctgaa ggagaaggat tacctggaca
   125341 agttattgtc aaaaccaaaa aatctttggt aatagctgct ggtcaaggag ccctgtcatt
   125401 gctggttgtg caacctgcgg ggaaacctaa aatggctatt gcagatttct taaatggcct
   125461 tggtagaaaa cttgaagtgg gtgatttcat tggcagataa ttggaaaata agtattcgag
   125521 gaaaagcact tctaacctta gaacatattt ttgatcaggg ggcttacaca aacatagcgc
   125581 ttaatcagca gctaagcaat aaagctttat ctgctaagga cagagctcta ttaactgaga
   125641 ttgtatatgg taccgtttca cgtaaaatta gcttggaatg gtatttagcc cattatgtca
   125701 aagaccgaga taaattggac aaatgggttt attatctcct tatgctcagt ctttatcaac
   125761 tgatttattt agataagtta ccagcgcatg ccattgttaa cgatgcggtt ggtattgcca
   125821 aaaatcgtgg caataaaaaa ggtgcagaga agtttgtcaa tgctatttta cgtcaattca
   125881 ccagccatcc tctcccagat atggaaacaa ttaagcgtcg aaataagtat tattcggtca
   125941 agtattcact gcctgtttgg ttggttaaaa agttagaaga ccaatttggt tctgacagat
   126001 cagtggccat catggaaagt ttatttgtgc gtagtaaggc tagtattcgc gtgacagacc
   126061 ctttgaagct agaggaagct gctgaggctt tagatgcaga acgttccctt ttatcagcaa
   126121 ctggtttaac caaagcgtca ggtcattttg cagccagtga ttatttcaca aatggggaca
   126181 tcactattca agatgaaagc agtcagcttg tagctcctac tttaaacatt gacggtgacg
   126241 acataattct tgatgcatgt agcgctccag ggggcaagac ctctcatata gcatcttact
   126301 taaaaacagg taaagttatt gccttagatc tctatgatca taaactagag ttggtgaagg
   126361 aaaatgctaa ccgcttagga gttgctgata acattgagac aagaaaacta gatgccagag
   126421 aggttcatcg tcattttgaa aaggatagct ttgataagat tttggtggat gctccttgct
   126481 caggaattgg tttgattcgt cgaaaacccg atatcaaata taataaagaa agtcaagatt
   126541 tcaatgctct acaggctatc cagctagaga tattgtctag tgtttgtcaa accttgcgta
   126601 aaggtggtat aataacatac agtacttgca ctatttttga tgaggagaat cgtcaagtca
   126661 tcgaagcatt tttacaaagt catcctaatt ttgaacaagt aaaactgaac catacacaag
   126721 cagatattgt caaggatggt tatcttatta tcacaccaga acaataccag actgatggct
   126781 tctttattgg acaagtcaga cgagtcttgt agtattttag gaggaaactg actgagtcag
   126841 aaaaaacgta tgaagatttc attaaaaaca gacattgggc aaaaacgctc aaacaatcaa
   126901 gattttatca ataagtttga taataaaaaa ggcatcactt tagtgatttt agcagacggt
   126961 atgggtggcc acagagctgg aaatattgcc agtgagatga cagtcacaga cctgggaaga
   127021 gaatgggtaa aaacagactt cacagagtta agtcagatta gagattggtt atttgaaact
   127081 atccagtcag aaaatcaacg gatttatgat ctaggccaat cagaagactt taaaggaatg
   127141 ggaacgactg ttgaagcagt agctttagtt gaatctagcg ccatttatgc tcatattggt
   127201 gattcacgga ttggtcttgt ccatgatggg cattatacct tattgaccag tgatcattct
   127261 ttagtgaatg agttggttaa ggcaggacag atcacagaag aagaagctgc tagccatcca
   127321 caaagaaata ttatcactca atctattggt caagcttccc cagtagagcc tgatttagga
   127381 gtgagggttt tggagccagg ggattatctt gtcattaaca gtgatggtct aaccaatatg
   127441 atttcaaatg atgaaattgt gactatcttg ggcagtaagg ttagtcttga tgaaaaaaac
   127501 caagaaatga ttgacttagc taacctaaga ggaggcctag ataatattac aatcgctttg
   127561 gttcacaacg aaagtgagga cgtcgaatga ttcagattgg caaattattt gctggtcgtt
   127621 atcgcattct gaaatctatt ggccgcggtg gtatggcgga tgtttattta gcaaatgatt
   127681 tgatcttgga taatgaagac gttgcaatca aggtcttgcg taccaattat caaacagatc
   127741 aggtagcagt tgcgcgtttc caacgagaag cgcgggccat ggctgaattg aaccatccca
   127801 atattgttgc catccgggat ataggtgaag aagacggaca gcaattttta gtaatggaat
   127861 atgtggatgg tgctgaccta aagagataca ttcaaaatca tgctccatta tctaataatg
   127921 aagtggttag aattatggaa gaagtccttt ctgctatgac tttagcccac caaaaaggaa
   127981 ttgtacacag agatttaaaa cctcaaaata tcctactaac taaggagggt gttgtcaaag
   128041 taactgattt cggcatcgca gtagcctttg cagaaacaag cttgacacaa actaattcga
   128101 tgttaggcag tgttcattac ttgtctccag aacaggctcg cggctccaaa gcgacgattc
   128161 aaagtgatat ttatgcgatg gggattatgc tctttgagat gttgacaggc catatccctt
   128221 atgatggcga tagtgctgtt acgattgcct tgcaacattt tcaaaagcct cttccatcta
   128281 ttatcgagga gaaccacaat gtgccacaag ctttggagaa tgttgttatt cgagcaacag
   128341 ccaagaaatt aagtgatcgt tacgggtcaa cctttgaaat gagtcgtgac ttaatgacgg
   128401 cgcttagtta taatcgtagt cgggagcgta agattgtctt tgaggatgtt gaaagtacca
   128461 aacccctccc caaagtggcc tcaggtccca ccgcttctgt aaaattgtct ccccctaccc
   128521 caacagtgtt aacacaggaa agtcgattgg atcaaactaa tcaaacagat gctttacagc
   128581 cccccaccaa aaagaaaaaa agtggtcgtt ttttaggtac tttattcaaa attctttttt
   128641 ctttctttat tgtaggtgta gcactcttta cttatcttat actaactaaa ccaacttctg
   128701 tgaaagttcc taatgtagca ggcactagtc ttaaagttgc caaacaagaa ctgtatgatg
   128761 ttgggctaaa agtgggtaaa atcaggcaaa ttgagagtga tacggttgct gagggaaatg
   128821 tagttagaac agatcctaaa gcaggaacag ctaagaggca aggctcaagc attacgcttt
   128881 atgtgtcaat tggaaacaaa ggttttgaca tggaaaacta caaaggacta gattatcaag
   128941 aagctatgaa tagtttgata gaaacttatg gtgttccaaa atcaaaaatc aaaattgagc
   129001 gcattgtaac taatgaatat cctgaaaata cagtcatcag tcaatcgcca agtgcgggtg
   129061 ataaatttaa tccaaacgga aagtctaaaa ttacgctcag tgttgctgtt agtgatacga
   129121 tcactatgcc tatggtaaca gaatatagtt atgcagatgc agtcaatacc ttaacagctt
   129181 taggtataga tgcatctaga ataaaagctt atgtgccaag ctctagctca gcaacgggct
   129241 ttgtgccaat tcattctcct agttctaaag ctattgtcag tggtcaatct ccttactatg
   129301 gaacgtcttt gagtctgtct gataaaggag agattagtct ttacctttat ccagaagaaa
   129361 cacactcttc tagtagctca tcgagttcaa cgtcaagttc aaacagttct tcaacaaatg
   129421 atagtactgc accaggtagc aacactgaat taagcccatc agaaactact gctcaaacac
   129481 cttaacaaag aatagttagt ctcatgtttt actagcatgc cactaactat tctttttaac
   129541 tactcgtcat ataaagatgc aattttccag gaattctgat aaaatacaaa gaaataaggg
   129601 gaaactaatg aaaaaatttc aattcttttt acttatcgag tgtatactgc tagctatggg
   129661 tatcatgaca atcttggata atgatttatc aagttttatc ctaattctag ttcttatctt
   129721 attagcatta cgcttttata accaagatag ccgcaataat tttttactaa ctgtcagttt
   129781 attgtttctt tttttaattt tcatgcttaa tccctacatt atcatggctg ttcttttggg
   129841 gatagtttac attttcatta accatttttc acaagtcaaa aagaagaatc gctttgcctt
   129901 gattcgtttc aaggaagaaa agattgaagt gaacaatacc aagcatcaat ggattggtac
   129961 tgctaattat gaaagtgatt attattgttt tgatgacatt aacatcattc gaatctcagg
   130021 aaatgacacg gttgacttaa ccaatgttat tgtgacagga atggataata tcattgtgat
   130081 acgtaaaatt tttggaaata cgactatatt ggtacctatt gatgtcactg ttactttaga
   130141 tgttagttcc atatacggaa gtgttgattt ttttagatgt cagcaatatg atttgcgcaa
   130201 cgaatctatt aagttaaaag aaacggataa ccaatccctt aaaaaagtca aaattatcgt
   130261 tacaactatt gccggaaatg ttgaggtgga taggcgatga aaaaacgtta ctatgctctt
   130321 gtttggctct actcaaccat taccatttta tctattgttt ttgtggtcat ggataattta
   130381 ggaatcactt ttaactacct tcgcaatcat ttatggcagg tcgaacgtct agggttttcg
   130441 attttattgt tgattgtttc tgtgacttta ttattgttgt tattgtggat tattatggat
   130501 gataacagta agcgtaacat caaccaaaat ctaaaatata ttctcaataa tcgacgactc
   130561 tatctagatg agacatcaga aatcaatact aatttaagtc gactttctaa aaaaatgtct
   130621 cacctgactg ctaacatgca aaagaaagaa agtgcttata ttcttgatag ccaagaagtt
   130681 gtaaaacaag agcgcaaacg aattgcaaga gatttacatg acacagtcag tcaagagcta
   130741 ttcgcttcgt cattgatttt atcaggaatt tcaatgagtt tggaacaact ggacaaaaca
   130801 caattacaaa cacagttaac aacggttgaa gcaatgttgc aaaatgctca aaatgatcta
   130861 cgcattctcc ttttgcatct tagacctacc gagctagcta atcggacttt atctgagggc
   130921 cttcatatga ttcttaagga attaacagat aaaagtgata ttgaagtcat ttataaggaa
   130981 accattgctc agcttcctaa aacaatggaa gataatcttt ttagaattgc ccaagaattc
   131041 attagcaaca cgttaaaaca tgctaaagct agtcgaattg aagtttatct caatcaaacc
   131101 tcaacagaat tacaattgaa gatgattgat gatggtgtag gatttgatat ggatcaggta
   131161 agggatttga gttatggtct gaagaatatt gaagaccgtg tcaatgattt agcaggaaac
   131221 ctacatttaa ttagtcaaaa aggcaaagga gtttccatgg atattagact gccgatagtg
   131281 aagggagatg acgatgagta agataaaagt gatattggtc gatgatcatg aaatggtccg
   131341 catgggactc aagagttttt tgaatttaca agctgatatt gatgtcgttg gtgaggcctc
   131401 taatggacgt gaaggggttg atttggcatt ggctttgaag ccagatgttt tggttatgga
   131461 tctagtgatg ccagagttag gcggtgttga ggcaacttta gaagttctaa aaaaatggaa
   131521 agaggctaag gtacttgtgt taacttccta tctagataat gaaaagatat accctgtcat
   131581 tgatgcagga gcgaagggtt atatgttaaa aacatcgagt gcggctgaaa ttttaaatgc
   131641 cattcgcaag gtttcaaagg gagagttagc tattgaaaca gaagttgaca aaaaaattaa
   131701 ggcgcatgat caacaccctg acttgcatga ggaactaaca gcgcgtgagt atgatatttt
   131761 acacctttta gctaaagggt atgataatca gaccatcgct gatgaactct ttatttcctt
   131821 aaaaaccgtc aaaacacatg tgtccaatat tctagccaag ttagaagttg atgaccgaac
   131881 ccaagcggtt gtctatgctt ttcgacatca tttagtcccc caagacgata attaatgcta
   131941 taatataggg tatagcaaat tggaggaaag tatggacgca aaactaaaat acaaagctaa
   132001 aaaaatcaaa atggtgttct ttgatattga tgataccttg agggtcaaag atacgggtta
   132061 tatgcctgag tcgattcaaa gagtatttaa ggctttgaag gcaaaaggca tcttggttgg
   132121 tattgcttca ggtcgcgctc ggtacggtgt tccacaagaa gttcaagatt tacatgctga
   132181 ctattgtgtc aaattaaatg gagcttatgt caaagacgat gctaaaacta ttattttcca
   132241 agctccgatt ccagcagatg ttgttgtggc ctataaaaaa tgggcggatg atatgggcat
   132301 tttttatgga atggcgggtc gtcatgaagc ggtgttgtcc gctcgaaatg acatgattag
   132361 caatgctatt gataatgtct acgctcaact agaggtctgt ccggattata atgagtatca
   132421 tgatgtttac cagatgtgga ctttcgagga caagggagat ggcttgcagt tgcctgctga
   132481 attagcagag caccttcgtt tggtcagatg gcacgataac tcatcagatg ttgtcttgaa
   132541 aggtacgtca aaagcgctag gtgtttcaaa agtagttgac catttaggat taaaacctga
   132601 aaacattttg gtttttggag atgaactcaa tgacctagag ttatttgact atgctggtat
   132661 cagtattgca atgggagtat cacatccatt actgcaagaa aaagcagatt ttatcacaaa
   132721 aaaagttaaa gaagatggca ttttatatgc cttggaggaa ttaggattga ttgacaaaga
   132781 attacagttt ccacaattgg atttgccaaa ccataaagga ccaaaagcaa ccattaaaac
   132841 aaaccatggc gatatgaccc tggtcttgtt cccagatcat gctcctaaaa cagtagccaa
   132901 tttcttaggt ttggctaaag aagggtacta tgatgggatt atcttccacc gtattattcc
   132961 tgaatttatg attcaagggg gcgatccaac aggaacagga atgggtggac aatccatcta
   133021 tggtgaaagt tttgaagatg aattttcgga tgaactctat aatctccgtg gggccttgtc
   133081 gatggctaat gcgggaccaa atactaacgg cagtcagttc tttattgttc aaaatagtaa
   133141 gattccttat gccaaaaaag aactagaacg tggtggttgg ccggctccaa ttgcagcttc
   133201 ttacgctgca attggtggaa ctcctcacct tgatcgtcgt catacggtct ttggtcagct
   133261 tgtggacgaa acttcattcc aagttttgga tttgattgct ggcgttgaaa ctggcgcaca
   133321 ggataaacct aaagaagacg ttatcattga aacaatcgag gtatttgact aatgaaaatt
   133381 ggcgacaaac tgcatggcac catcactggg attaaaccat acggagcctt tgttgccctt
   133441 gaaaatggga caacaggtct cattcatatt tcagaaataa aaacgggatt tattgacgat
   133501 attgatcaat tattggctat aggcaaccag gttttagtac aagtaattga tattgatgaa
   133561 tatagtaaaa agccaagttt atctatgcgg accttagcag aagaaaaaca gcattttttc
   133621 catcgtcatc gttattccaa cagtcggcac aagattggct ttaggccact tgaagagcag
   133681 ttacctcagt ggattgaaga aagcctgcag tttttaaaaa agaacactaa aaagagtctg
   133741 gaaccttagt agttccaaac ccttttttat ttcgtcttaa ttactggcac atcatagagt
   133801 tcagtcgata aatagcgttc gccattatct ggtaaaatag ttaacacatg tttgcctttt
   133861 cctaattgtt tagcgacttc aatagcggcg taaagagcag ctccagaaga aatcccaacc
   133921 aggaagcctt ccttagctcc tgttagtcga gcagtttcta aagcatcttt cgatttaaca
   133981 cggataattt ggtcataggc tttggtatct aacgtgtttg ggataaatcc agctgatata
   134041 ccttgaattt tatgtggtcc aggctcttga ccagataaga cagcagattc ttcagcttca
   134101 acagcataga taacagtttc agggctagct tttttcaaga catgtgaaac accagaaagt
   134161 gttcctccag taccaacacc agatacgaat gcatctaaag aaatctcctt aaaagcttcc
   134221 aaaatttctt gagctgttgt tttttcatgg atgcttggat tggcagggtt attaaattgc
   134281 ataggcatcc aagcacctag ttctattgct aaagtttcag cttttgcaat agcccctttc
   134341 ataccttctg ctccaggtgt taagacaagc tctgcaccat aagcctgaat gatttgtcgt
   134401 ctttccaagc tcatagtttc gggcataaca ataatgactc gatacccttt agcagcacct
   134461 acccatgcaa gaccaatacc tgtattaccg cttgttggtt cgataataac gtcaccagga
   134521 cttatcagac cttcagcttc agcagcttca atcatcgata aagcaatacg atctttaaca
   134581 gaagatcctg ggttaaaagc ttctaatttt acataaacgt cagcagcttc gtttggaatt
   134641 aaacagttaa gtttgataat aggtgtttga cctactaatt ctgttatagt tttgtaaatt
   134701 ttagtcatag tttagcctct tttcttgata caaaataaat acgctgtgta tttaagtata
   134761 aggagagata ttattaaagt aaaatacaga tttactatca ctctgataat aaagccatat
   134821 cacttttgtt gatgattaat cacaggggaa ttcaataact ttggatccga ttttctcaca
   134881 gcttatctga ccatgataat aatttgttaa agtatcaatg agattttcca cacgttcagt
   134941 atcacaataa agtgttgtct ttatcgtgtc tgaaaactta gtttctgttt cggttaaagc
   135001 caattgatct agcaagttag agtatagttg gtattgggga taagaaagtg tgatttctag
   135061 tcctatctgc tgtttaactt caatgatgcc aaatcgttta atagctgttg cggtcatgtt
   135121 agagtatgct ctgattagcc cacctgttcc taatttaata ccaccaaagt aacgcgttac
   135181 cacaactact acatttgtta aacactgctt ttctaacaca gaaaggatag gtattccagc
   135241 agttcctgaa ggttcaccat catcacttga gcgcttgatc tgactgttgt taccgataat
   135301 catcgcaaag caggaatgat tagctttgta atgttctttt ttgatagcat taacaaaatt
   135361 cttaccatct tcttcagtgc ttactcgttt gatatgacaa atgaaacgag attttttaat
   135421 actttcttcg aaaaaaccac tggctttgat tgtcttaaaa tgttccataa aaaaattgta
   135481 caagaaaaga taaaaattag caaaaaaaag cgaataataa agtatggagt ctattgaaaa
   135541 tagttatgga cgattgttgc tagaaagcca gttaccagat tcagcaaagc agcttgctca
   135601 acctttaaaa agtgtagtaa tatcgagagg aaaaatgatt tgtcaacgtt gtcactatca
   135661 gcttgatgaa gaagcacgat tgccaaatgg agcctattat tgccgatttt gtcttgtctt
   135721 tggacgaaat caatcagata aattgctcta tgctatccca cctatgcatt ttccaaaagg
   135781 taattatctg gtttggagcg gtcaactaac tgcttatcaa gagatgattt cccaacaatt
   135841 attaatcaat atgcaaaatc aaaaaacaac attagttcat gctgtaactg gtgcaggaaa
   135901 aacagaaatg atttatgctg cgattgaggc ggtaattaac acaggtggct gggtttgcat
   135961 tgccagccca agagtagatg tttgtgtaga ggtggctact cgtttatccc aagccttctc
   136021 ctgcagcatc tgtttaatgc acgcagagtc tcttccttat caaagagctc ctattatagt
   136081 agccacaacg catcagctgc taaaatttca caaggctttt gatctcttaa ttattgatga
   136141 agtagacgca ttcccttttg taaataatat tcaacttcat tatgctgcaa gtcaggcttt
   136201 aaaagaaggt ggcgcaaaga ttttattaac tgcaacttca actagaactt tagaaagaaa
   136261 ggtaaacaag ggagaagtag tcaagctgac attggcgaga cgctttaata ataggccatt
   136321 agttattccg aaatttataa gaagttttaa tctatttaaa atgatacatc ggcaaaaact
   136381 tcctcctaaa attttaaaat acttaaaaaa acaaagaaaa acaggctatc cccttttaat
   136441 ttttctaccc actattataa tggcagaatc tgttacagca atcttaaaag agttattgcc
   136501 cgccgaacaa atagcttgtg tttctagtca atcacaaaac aggaaagaag atatcacagc
   136561 ttttcgtcaa gggaaaaaaa cgattttaat tacaacaaca attttagaaa ggggtgtgac
   136621 atttccccaa attgatgttt ttgttcttgg gtctcatcat cgtgtctata gttcccaaag
   136681 tcttgttcaa attgctggac gagttggaag atctatagac agaccagacg gaacgttata
   136741 tttctttcat gaaggtatca gtaaagcaat gctactagca agaaaagaga ttaaagaaat
   136801 gaattataaa gggtattcgc atgatctgtc tactatgtca acaaattagt caaacaccaa
   136861 taagtattac agaaatcatc tttttaaggc gtatctcttc accgatttgt caacaatgtc
   136921 aaaaaagctt tcaaaagata ggaaaaagtg tttgtgcgac atgttgtgca aactcagata
   136981 taatagcttg tcgagattgt ctaaaatggg aaaacaaagg atacaatgta aatcatagaa
   137041 gcttatattg ttataatgct gctatgaaag catacttcag tcaatataag tttcaaggag
   137101 actatttatt aagaaaagtt tttgcagtag aacttgccga tgttattacc aagtactata
   137161 aaggctatat cccagtcccg gttcctgtaa gtcccggttg ttttcgagaa agacaattta
   137221 atcaagtgag cgctattctt gaggcagcta atgttagcta cctttctctt tttgaaaagc
   137281 tagataatac tcaccaatct tccagaacaa aaaaagagag attattagta gaaaaatctt
   137341 atcgactact aaaagtatca aacattcctg ataaaatcct tatagtagat gatatttata
   137401 ctactggtag tacaattatc gctcttagaa aacaattggc taaagtagca aatagtgaca
   137461 ttaaaagttt gtcaattgca cgttaaaact tgcaaatttt catgaaagca gtataatagt
   137521 attaaagata aagtaagcgc ttcaagcgcg agaaagaggt atcctatgat taagttcagt
   137581 attcgtggag aaaatatcga agtgacagaa gctattcgcg attatgtaga atcaaagctt
   137641 actaaaatcg aaaaatattt tgctaaagac caagaaatag atgcacgtgt taatttaaaa
   137701 gtttatcggg agagatcttc aaaagttgag gtaacgatcc cattagattc agtaaccctt
   137761 cgtgctgaag atgtttcaca ggatatgtac ggctctattg atttagttgt tgataagatc
   137821 gaacgccaaa ttagaaaaaa taaaaccaaa attgctaaaa aacatcgcga aaaggttcca
   137881 actggtcaag tctttacaac tgagtttgaa gctgaagaag tcgatgagat accagaagta
   137941 caagttgtac gtactaaaaa tgtgacatta aaaccaatgg atgttgaaga agcgcgttta
   138001 cagatggaac tattgggaca tgatttcttt atctacactg attctgaaga tggtgcaaca
   138061 aacattttat accgtcgcga agatggaaac ctaggattaa tagaagctaa atagttcaca
   138121 actaaaacct acagggatga ttatacgtat tttaaaagtg ggaaaaagct attcatgttt
   138181 cgaggtgaca tgatgaaaat gagattaagt gatagatacg acagtcatta tataacaaaa
   138241 gtatctatta cagttcctct ttaagtaaat cttacgtaaa attagtttga aaaaaagatt
   138301 agtcccaatt ctgggctaga aattctcaaa aaatatgaaa aagcgcgttt tcagaatata
   138361 aagcgcgttt ttttcttttt ccatttaaca ataaaaaact catgacgaac atggtatcat
   138421 aagagaattt ttacttttta aaaaaaggtc aaagactttc tgacaccaaa taaaaataga
   138481 attttttcta actaaaaata atagcacaat ctttggcagc aatctgaatt gtttttccat
   138541 aaaagattta agcacttacg tttgcttaaa atataggtta tgtgacgtgc gtgcaagatc
   138601 agattataac aaaatagttc caaataagcc tatcactgag aaagcatcac agaagggtta
   138661 aacttttttt gtattagtgt tttatcagta caacctaaca cttattttta taaaaaaata
   138721 aaaaagctat tgacaatctt ata
//
LOCUS       DATWEK010000002       101178 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.002, whole genome shotgun sequence.
ACCESSION   DATWEK010000002 DATWEK010000000
VERSION     DATWEK010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 101178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 101178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..101178
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.002"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            187..1401
                     /gene="sstT"
                     /locus_tag="VCR92_000141"
     CDS             187..1401
                     /gene="sstT"
                     /locus_tag="VCR92_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEP4267240.1"
                     /translation="MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLF
                     VGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIVLYLFGTFASALVAVLTAYLFPL
                     TLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKA
                     ASQETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLV
                     GTMVFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKI
                     GLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLLSVVAAVSAC
                     GASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKRKKA"
     gene            complement(1456..2130)
                     /locus_tag="VCR92_000142"
     CDS             complement(1456..2130)
                     /locus_tag="VCR92_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEP4267241.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNFDQDVIAIDIRESHVKEVA
                     DLVTKAAVGDITDKEFLLAVGIEHCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRRHIESIIYLEHGISMIEFVIPKSW
                     EGQSLSELDVRRKYELNVIGMRQKEVKTLDTNVKPFEPLEPNTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(2140..3531)
                     /locus_tag="VCR92_000143"
     CDS             complement(2140..3531)
                     /locus_tag="VCR92_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEP4267242.1"
                     /translation="MSGGNMKRSFIKSLSVTQRLTFSFAIVILIGTLLLSMPFTHYQN
                     GPNTVYLDHFFNVVSMVCVTGLSVVPVAEVYNGIGQTIAMALMQIGGLGLVTLIAVST
                     FALKRKMRLSDQTLLQSALNRGDSKDLKHYLFFAYKVTFSIEAFAAIVIMIDFIPRFG
                     WKNGIFNSIFLAVSAFCNAGFDNLGSSSLKDFMLNPTLNVIITFLIISGGLGFAVWVD
                     LGVAFKKYFFERPHCYGATFRKLSNQSRLVLQTTAVILFLGTFLTWFLEKDNSKTIAN
                     FSLHQQLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKVT
                     TAAITFLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGFILLLSVEPH
                     IAPIPLLFESISAIATVGVSMDLTPQLSTAGRLIVIVLMFVGRVGPITVLISLIQRKE
                     KTIQYATTDILVG"
     gene            complement(3601..4314)
                     /gene="rsmG"
                     /locus_tag="VCR92_000144"
     CDS             complement(3601..4314)
                     /gene="rsmG"
                     /locus_tag="VCR92_000144"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEP4267243.1"
                     /translation="MTPQDFYRTLEEDGFSLSSKQKEQFDTYFKLLVEWNTKINLTAI
                     TEENEVYLKHFYDSIAPILQGFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTIIDS
                     LNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVVTARAVARMQVLSELT
                     IPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNHSYQLPNGDSRFITIVEKK
                     KETPNKYPRKAGLPNKKPL"
     gene            4464..5021
                     /locus_tag="VCR92_000145"
     CDS             4464..5021
                     /locus_tag="VCR92_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEP4267244.1"
                     /translation="MPTVLIILVVLGVLALWLMISYNSLVKSRMHTKEAWSQIDVQLK
                     RRNDLIPNLIETVKGYASYEQKTFEKITDLRARVANASTPQETMAASNELSKQVTSLF
                     AVAENYPDLKANENFLKLQEELTNTENKISYSRQLYNSTTSNYNLQLESFPSNIAGKL
                     FGFKPSEFLQTPEAEKEVPKVEFNF"
     gene            5068..5964
                     /gene="htpX"
                     /locus_tag="VCR92_000146"
     CDS             5068..5964
                     /gene="htpX"
                     /locus_tag="VCR92_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEP4267245.1"
                     /translation="MLYQQISQNKQRTVVLLVVFFALLALIGASAGYLLLDNYAMGLV
                     LALVIGVIYATSMIFQSTSLVMSMNNAREVTEKEAPGFFHIVEDMAMVAQIPMPRVFI
                     IEDPSLNAFATGSSPQNAAVAATTGLLEVMNREELEGVIGHEISHIRNYDIRISTIAV
                     ALASAVTVISSIGGRMLWYGGGSRRQRDDGDDDVLRIITLLLSLLSLLLAPLVASLIQ
                     LAISRQREYLADASSVELTRNPQGMINALEKLQLSQPMKHPVDDASAALYINEPRKKR
                     SFSSLFSTHPPIEERIERLKNM"
     gene            6198..6731
                     /locus_tag="VCR92_000147"
     CDS             6198..6731
                     /locus_tag="VCR92_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEP4267246.1"
                     /translation="MLAISEIRKHPDGLSFDRLCDVKSMLLERDQQIIDIKAVKAVGN
                     VRYDKGLYLLDYQLSYEVILPSSRSMVPVCLSEVQHIQELFIEATDLADKKELVEDNL
                     VLVLDKDAINLEESIVDNILLAIPLQVLTEEEKKSKELPAGQNWAVLTEEDYQCLKEE
                     KQKENNPFASLQGLFDE"
     gene            6998..7684
                     /gene="covR"
                     /locus_tag="VCR92_000148"
                     /gene_synonym="csrR"
     CDS             6998..7684
                     /gene="covR"
                     /locus_tag="VCR92_000148"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEP4267247.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALE
                     KEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            7839..9203
                     /gene="covS"
                     /locus_tag="VCR92_000149"
                     /gene_synonym="csrS"
     CDS             7839..9203
                     /gene="covS"
                     /locus_tag="VCR92_000149"
                     /gene_synonym="csrS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CovS"
                     /protein_id="HEP4267248.1"
                     /translation="MKKEKQSVFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDKTHLR
                     IDDRKGSRVIRSERDITNTLDANQDIYVYNIDKQMIFTTDNEESSPGLHGPIGRVYHD
                     HIEDQYRGFSMTQKVYSNRTGKFVGYVQVFHDLGNYYVIRARLLFWLLVVELFGTSLA
                     YLIILITTRRFLKPLHNLHGVMRNISENPNNLNLRSDISSGDEIEELSVIFDNMLDKL
                     ETHTKLQSRFISDVSHELRTPVAIIKGHIGLLQRWGKDDSDILEESLTATAHEADRMA
                     IMINDMLDMIRVQGSFEGHQNDMTVLEDSIETVVGNFRVLREDFIFTWQSENPKTIAR
                     IYKNHFEQALMILIDNAVKYSRKEKKIAINLSVTGKQEAIVRVQDKGEGISKEDIEHI
                     FERFYRTDKSRNRTSTQAGLGIGLSILKQIVDGYHLQMKVESELNEGSVFILHIPLAQ
                     SKES"
     gene            9418..9912
                     /gene="nrdR"
                     /locus_tag="VCR92_000150"
     CDS             9418..9912
                     /gene="nrdR"
                     /locus_tag="VCR92_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEP4267249.1"
                     /translation="MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERV
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENVISRIEQEVRTTYENE
                     VSSTAIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITNRVRGKKKRLNN
                     DETN"
     gene            9896..11071
                     /locus_tag="VCR92_000151"
     CDS             9896..11071
                     /locus_tag="VCR92_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEP4267250.1"
                     /translation="MMKPIDTFTYLKRNKVTLDSVTLIQLYFPIIGSDAVSIYQYFIH
                     FFDDGLQRHKFSDILNHLQFGMKRFEDALAILTAMELVSVYQLSDTYLITLHQPLSRD
                     LFFQHPAYSRLLEQKIGEVAVSELQVTVPSQARNISKRFSDIFGVQGDLTNVPQKPQK
                     NFDLSSFQQLMVRDGLQFEDNQKDIISLYSIAEQYDMTWFDTYQIAKATAVNGKIRPE
                     RLLAKKNQSMTKPSKENFSQAEQIILREAKQDSALVFLEKIKKARRATITKDERILLQ
                     TLAKMNFLDDVINVMVLYTFNKTKSANLQKSYVLKMANDFAYQKVSTAEEAIVVLRAF
                     TDRQSRRQSKVKTSQSNVPKWSNPDYQETTSQEEQAKLDQFKQAALKRLENLGKGGD"
     gene            11072..11974
                     /gene="dnaI"
                     /locus_tag="VCR92_000152"
     CDS             11072..11974
                     /gene="dnaI"
                     /locus_tag="VCR92_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEP4267251.1"
                     /translation="MEKIGETMAKLGQNTRVNSDQLIQTILADPEVASFISQHHLSQE
                     QINLSLSKFNQFLVERQKYQLKDPSYIAKGYQPILAMNEGYADVSYLETKELVEAQKQ
                     AAISERIQLVSLPKSYRHIHLPDIDVNNASRMEAFSAILDFVEQYPSAEQKGLYLYGD
                     MGIGKSYLLAAMAHELSEKKGVSTTLLHFPSFAIDVKNAISNGSVKEEIDAVKNVPVL
                     ILDDIGAEQATSWVRDEVLQVILQYRMLEELPTFFTSNYSFADLERKWATIKGSDETW
                     QAKRVMERVRYLAREFHLEGANRR"
     gene            12037..13347
                     /gene="der"
                     /locus_tag="VCR92_000153"
     CDS             12037..13347
                     /gene="der"
                     /locus_tag="VCR92_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEP4267252.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDADEY
                     VSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDEIV
                     ENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DADGQEFTMIDTAGMRKSGKIYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTIDKDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQ
                     RLNKLPDLIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK"
     gene            13554..16652
                     /locus_tag="VCR92_000154"
     CDS             13554..16652
                     /locus_tag="VCR92_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEP4267253.1"
                     /translation="MMARLIPGRVRNEGIKLYEQGLVSFQDDNKGILQIEVETYQVQY
                     GADDEDITCQCDTFHMKHYCKHIAAVEYFLKNDQKGKLFLKQLTNQTKIKETTKKMTS
                     FGSLFLDSLAMNEDDSVKYRLSALGSRSPFSSDYWWSLKINRLPDDRSYVIRDIKGFL
                     QLIKKEGFYQIGKNYFEQLSWLQFDPSSQDLIEFLWRLASNTDKGDNENIFPNHARHL
                     RLPSGFFEEGIHYLTSLYDFTFEGPSQTYHHLFVRSLEAEAGLYEFKVEVHRKSIELQ
                     IAEKNVQYLFDNDYLLYQDTFYHLTLKQRKMVQAIRSLPIEADLAKHIHFDLDDHAKL
                     AASLSDFKQIGLVEAPKSFAIRDFEVTFQFDLLNRDEISCQLMFDYGNYQVSDKASLE
                     ALPFASHLKKEEKINRSLLAFGFSPQFYSKKRLTSAKELYTFFEETVPCFERLGNVAL
                     STAIQALQVKEMPKIAIRRNQGLLDISFDFSTIIENDIDQAVTALFQNNPYFVSQTGQ
                     LVVFDDETQKVSKSLQELRARQLKNGHLQLDGIRALQVSKLFEGMTSVHFSKELEELA
                     YHLQHPETFSIKPLPVKAQMRDYQRNGVQWLSMLNHYGFGGILADDMGLGKTLQTLAF
                     LASHLKSDSKVLILSPSSLIYNWFDECQKFTPQLDVVVSYGLKQIRDQIIEEGHQITI
                     TSYSSFRQDFETYQAFHYDYLILDEAQVIKNAQTKISHCLRAFNTANCFALSGTPIEN
                     KMLEIWSIFQIVLPGLLPTKKEFLKLTAEQVSRYIKPFVMRRKKEDVLPELPDLIETN
                     YSNEMTDEQKAIYLAQLRQMKDQIRNSSDVDISRQKIEILSGITRLRQICDTPSLFMD
                     YQGKSGKLDSLRILLTQIKENGHRALIFSQFRGMLDLAKQEMTALGLTSYQMTGSTPA
                     NERQEMTRAFNNGSKDAFLISLKAGGVGINLTGADTVILIDLWWNPAVEMQAISRAYR
                     IGQKENVEVYRLITRGTIEEKILELQESKRNLVTTVLDGNENRASMSIEEIKEILGLN
                     TH"
     gene            16895..17497
                     /locus_tag="VCR92_000155"
     CDS             16895..17497
                     /locus_tag="VCR92_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267254.1"
                     /translation="MVKNQFPLVADGIAISDPAKQMALYENEDLITNIRGYYQDKEYD
                     DIARNEEFTAKATSRQAPSSKRFCSNDEKHHYVKEARQKAKQDLKEKRQAYLAKEMAY
                     VPKQVSKKQQPADSSPSQKQATTEMSRFTKKLHQDNYILAELPKEYKEPKNLPQQGTT
                     KKNNYDFLKSSQIYNNKEMRQQREKTIAQELNLSRFEDLP"
     gene            17537..18865
                     /locus_tag="VCR92_000156"
     CDS             17537..18865
                     /locus_tag="VCR92_000156"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEP4267255.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNITPDMELIVGNAFRENNKEVAYALRHQIPFKRYHDFLGDFMKSF
                     ISFAVAGAHGKTSTTGLLSHVLKNITDTSYLIGDGTGRGSANAQYFVFESDEYERHFM
                     PYHPEYSIITNIDFDHPDYFTGIADVRNAFNDYAKQVKKALFVYGEDDELKKIEAPAP
                     IYYYGFEEGNDFIAYDITRTTNGSDFKVKHQGEVIGQFHVPAYGKHNILNATAVIANL
                     FVAGIDTALVADHLKTFSGVKRRFTEKIINDTIIIDDFAHHPTEIVATIDAARQKYPS
                     KEIVAIFQPHTFTRTIALLEDFACALNEADSVYLAQIYGSAREVDKGEVKVEDLAAKI
                     IKPSQVVTVENVSPLLDHDNAVYVFMGAGDIQLYEHSFEELLANLTKNNQ"
     gene            18911..19393
                     /locus_tag="VCR92_000157"
     CDS             18911..19393
                     /locus_tag="VCR92_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP4267256.1"
                     /translation="MLIRQVQGSDLEVIATIESDNFSPQEATTRAVLEERIRLIPDTF
                     LVALIDQEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQGVG
                     TALLAALKDLVVAQQRTGLILTCHDYLISYYEMNGFINQGISESQHGGTLWYQMIWKL
                     "
     gene            19505..21079
                     /gene="mltG"
                     /locus_tag="VCR92_000158"
     CDS             19505..21079
                     /gene="mltG"
                     /locus_tag="VCR92_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEP4267257.1"
                     /translation="MALTDFKDKDQQDQQRSFKEQILAELEKANQIRKEKEEELFQKE
                     LEAKEAARRTAQLYAEYKRQDAFQKESIAHNNKTAKHFQAIKGAVMTSEALKPTLLSE
                     KENSSLKTTNKRVVQANELQETASKESQVPLTIEKGHSVRRKLSKRQQTERAAKKIST
                     VLISSIIITLLAVTLAGAGYVYSALNPVDKNSDAFVQVEIPSGSGNKLIGQILQKKGL
                     IKNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEEIASALQEGGTAEPTKPSLGKILIP
                     EGYTIKQIAKAVEHNSKGKTKKAKTPFNEKDFLDLVTDEAFIQDMVKRYPKLLATIPT
                     KEKAIYRLEGYLFPATYNYYKETTMRELVEDMLAAMDATLVPYYDKIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNSGMALQSNIAILYAMGKLGEKTTLAEDATI
                     DTTINSPYNIYTNTGLMPGPVASSGVSAIEATLNPASTDYLYFVANVHTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            21152..21634
                     /gene="greA"
                     /locus_tag="VCR92_000159"
     CDS             21152..21634
                     /gene="greA"
                     /locus_tag="VCR92_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016481121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEP4267258.1"
                     /translation="MAEKTYPMTLTEKEQLEKELEELKLVRRPEIVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVIVQEVGTTD
                     KDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVRIESPAATYDVEIISVEKTN
                     "
     gene            complement(22254..23177)
                     /gene="yidC"
                     /locus_tag="VCR92_000160"
     CDS             complement(22254..23177)
                     /gene="yidC"
                     /locus_tag="VCR92_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEP4267259.1"
                     /translation="MKLTLNRILFSGLALSILFTLTGCVGRDAHGNPKGMIWEFLGKP
                     MSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQSEKMAFLKPVFEP
                     INKRIKQASSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFAAQYT
                     KGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMYTMPIMM
                     IFMSFSLPAGVGLYWLVGGFFSIIQQLITTYLLKPRLHKQIKEEYAKNPPKAYQSTSS
                     RKDVTPSQNMEQANLPKKIKSNRNAGKQRKR"
     gene            complement(23259..23537)
                     /locus_tag="VCR92_000161"
     CDS             complement(23259..23537)
                     /locus_tag="VCR92_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEP4267260.1"
                     /translation="MQKVRLIVSGRVQGVGFRYATHTLALDIGDIYGRVWNNNDGTVE
                     ILAQSKDSDKIATFIQEVRKGPSKWAKVTYVDVTMANFEDFQDFQIGK"
     gene            23798..24535
                     /locus_tag="VCR92_000162"
     CDS             23798..24535
                     /locus_tag="VCR92_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEP4267261.1"
                     /translation="MVITSKTNQLIKQTKKLLQKKHRKQSYLIEGWHLFEEAQKSGQV
                     FRHIFVLEEMVERLAGEQELVIVSPQVLKELTDSPSPQGIVAEVEIPKLAFPSDYKGK
                     YLVLEDVQDPGNLGTIIRTADAARFDGVFLSEKSADIYNQKTLRSMQGSHFHLPIWRT
                     DVYQLCRELQEYKTPILATTLSKKSVDYKSLTHHERLALVLGNEGQGISAEMAALADQ
                     LVHITMPGQAESLNVAVAAGILIFSLI"
     gene            24574..25074
                     /locus_tag="VCR92_000163"
     CDS             24574..25074
                     /locus_tag="VCR92_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEP4267262.1"
                     /translation="MHYTEDKEYMEHVGHLIAHPRFQKLSHIVQHQHSTRLEHSINVS
                     YSSYKLAKRFGWDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTEL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTMVDKYWAVKEAVTPLRQKWSNRRFLRRKT
                     LQSHNR"
     gene            25089..25778
                     /locus_tag="VCR92_000164"
     CDS             25089..25778
                     /locus_tag="VCR92_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEP4267263.1"
                     /translation="MNDHVIYTQSDVGLNQFFAKIYSLVGMGVGLSAFVSYLMLYPFR
                     ENLISILVNQPMIYYGAAIIELILVFVASGAARKNTPAALPIFLIYSALNGFTLSFII
                     VAYAQTTVFQAFLSSAAVFFAMSIIGVKTKRDMSGLRKAMFAALIGVVVASLINLFIG
                     SGMMSYVISVISVLIFSGLIASDNQMIKRVYQATNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRIFGRND"
     gene            25956..26198
                     /locus_tag="VCR92_000165"
     CDS             25956..26198
                     /locus_tag="VCR92_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEP4267264.1"
                     /translation="MSTAIWILLLIVALGVGVFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIIKQSKAAVSKGKK"
     gene            26376..27170
                     /gene="racE"
                     /locus_tag="VCR92_000166"
     CDS             26376..27170
                     /gene="racE"
                     /locus_tag="VCR92_000166"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEP4267265.1"
                     /translation="MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGP
                     RPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKAALDIPVLGVVLPGASA
                     AIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSVQVRSLACPKFVPIVESNEMCSSI
                     AKKIVYDSLSPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLL
                     NYFDINGNYHQKAVKHRFFTTANPEIFQEIASIWLKQKINVEHVTL"
     gene            27167..28153
                     /locus_tag="VCR92_000167"
     CDS             27167..28153
                     /locus_tag="VCR92_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEP4267266.1"
                     /translation="MSEKIYEYKDENNWFIGKMTGHNLISGWGVKHTTIKKIDDLLDG
                     IAATLDWENPKGYDVSVVRYQSPLSLITFIIDMINQETQRKIKVTPHAGTILLMENAK
                     LLAVYLPEGGVSTATFFATSEQGFGDIILIATRNEGKTKEFRNLFGQLGYRVENLNDY
                     PELPEVAETGTTFEENARLKAETISRLTGKMVLADDSGLKVDALGGLPGVWSARFSGP
                     DATDAKNNAKLLHELAMVFDQKKRSAQFHTTLVVAAPNKDSLVVEAEWPGYIATQPKG
                     ENGFGYDPVFIVGETGRHAAELEADQKNQLSHRGQAVRKLMEVFPAWQAKQS"
     gene            28132..28653
                     /locus_tag="VCR92_000168"
     CDS             28132..28653
                     /locus_tag="VCR92_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEP4267267.1"
                     /translation="MASKTIIVMSDSHGDRDIVQAIKDKYLGQVDAIFHNGDSELNSS
                     DPIWAGIYVVGGNCDYDTGYPDRLVTQLGTVTIAQTHGHLYHINFTWDKLDYFAQEVA
                     ADICLYGHLHRPAAWQVGQTLFMNPGSVTQPRGEINEKLYARVELTDTQIKVDYFTRD
                     HKLYPSLSKEFKR"
     gene            28650..29111
                     /locus_tag="VCR92_000169"
     CDS             28650..29111
                     /locus_tag="VCR92_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEP4267268.1"
                     /translation="MIAKEFETFLMSHLDNYLIPEQDLAIFIDTHNADHVMLLLVSNG
                     FSRVPVITREKKYVGTISISDIMMYQSKRQLTDWEMSQTDIGEMVNTKIETISITSSL
                     TEIMHKLIDFPFLPVVDRANRFVGIITRKSILKAVNSLLHDFTDDYTIIKK"
     gene            29108..29854
                     /gene="xerD"
                     /locus_tag="VCR92_000170"
     CDS             29108..29854
                     /gene="xerD"
                     /locus_tag="VCR92_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEP4267269.1"
                     /translation="MKSYIEPFIASKALSQNSQKAYRYDLQQFCQLIGERVNQDKLLL
                     YQNSIANLSLSAKKRKLSTANQFLYYLYQIKYLNSYFRLTDTMKVMRTEKQQAAIINT
                     DIFYQKTPFVWGQLISLLILELGLTPSEVAGIEVANLDLNFQMLTLKTKKGVRVLPLS
                     QILIPFLEQQLVGKEAYLFEHRGIPFSRQWFFNHLKTFVRSIGYEGLTAQKLREQFIL
                     KEKLAGKSIIELSDILGLKSPVTLEKYYKS"
     gene            29854..30558
                     /locus_tag="VCR92_000171"
     CDS             29854..30558
                     /locus_tag="VCR92_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEP4267270.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSQYKVDIYEVPIVEVIEQYLNYIET
                     LQVMKLEVAGDYMLMASQLMLIKSRRLLPKVVEHIEEEDLEQDLLEKIEEYSRFKAVS
                     QALAKQHDQRAKWYSKPKQELIFEDAILQEDKTVMDLFLAFSNIMAAKRAVLKTNHTV
                     IERDDYKIEDMMASIKQRLEKENVISLSAIFEECQTLNEVISIFLASLELIKLHVVFV
                     EQLSNFGAIILRKEKK"
     gene            30555..31106
                     /locus_tag="VCR92_000172"
     CDS             30555..31106
                     /locus_tag="VCR92_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEP4267271.1"
                     /translation="MTYLSQIEALLFVAGEEGLSLRHLASMLSLTPTALQQQLEKLSQ
                     KYEKDQHSSLCLIETANTYRLVTKEGFAELLRAYAKTPMNQSLSRASLEVLSIVAYKQ
                     PITRIEIDDIRGVNSSGALSKLLAFDLIREAGKKDVVGRPHLYATTDYFLDYMGINHL
                     DELIEVSAVEPADEEIALFRTQD"
     gene            31228..31950
                     /locus_tag="VCR92_000173"
     CDS             31228..31950
                     /locus_tag="VCR92_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEP4267272.1"
                     /translation="MRINKYIAHAGIASRRKAEELIKQGLVTLNGQVITDLATTVKSG
                     DVVEIEGSPIYNEEKVYYLLNKPRGAISSVSDDKGRKTVLDLLPQVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDTMIHPRNEIDKVYLARVKGIATKENLRPLTRGIVIDGKKTKP
                     ARYNIVRVEADKNRSIVELTIHEGRNHQVKKMFESVGLLVDKLSRTRFGTVDLKGLRP
                     GEARRLNKKEISQLHNLANTKK"
     gene            31947..32210
                     /gene="yidD"
                     /locus_tag="VCR92_000174"
     CDS             31947..32210
                     /gene="yidD"
                     /locus_tag="VCR92_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEP4267273.1"
                     /translation="MMKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGT
                     KGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA"
     gene            32388..32936
                     /locus_tag="VCR92_000175"
     CDS             32388..32936
                     /locus_tag="VCR92_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HEP4267274.1"
                     /translation="MTTKELINKNDKVKKARNHIVLFQPQIPQNTGNIARTCAATNAP
                     LHIIKPMGFPIDDRKMKRAGLDYWDKLELHFYDHLEQFINQCHGQLHLISKFAVNNYS
                     QATYADGDSHYFLFGREDTGLPEDFMREHAEKALRIPMNDEHVRSLNVSNTVCMVIYE
                     ALRQQGFQGLELKHTYEHDKLK"
     regulatory      33045..33169
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            33248..33811
                     /locus_tag="VCR92_000176"
     CDS             33248..33811
                     /locus_tag="VCR92_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEP4267275.1"
                     /translation="MSKTHKMIMIGILSAISFLLMLVSFAIIPGAAFLKIEFSIIPVL
                     FGLMIMDLKSAYLILLLRSLLKLFLNNRGVNDFIGLPMNIIAIALFVTAFALVWNRQK
                     TLSQYVFASLLGTGLLTFGMVVLNYTFAIPLYAIFANIDIRAYIGVTKYMMTMVIPFN
                     LVEGLIFAITFYFVYIASKPILERYLH"
     gene            33813..34466
                     /locus_tag="VCR92_000177"
     CDS             33813..34466
                     /locus_tag="VCR92_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEP4267276.1"
                     /translation="MMTNKQTHFLIASFALLIFVIIGYTVKFFPERLALLDNTIQAEI
                     RGNLPIVLTQFFRGVTVFGNVMTQVLLVIVSVLVLFFMKWKIEALFILSNGAIAAFLI
                     TTLKLFYQRPRPAIEHLVYAGGYSFPSGHAMGSMLIFGSLLIICYQRLHSKLLQFVTS
                     MIFIILILLIGLSRIYLGVHYPSDILAGFVLGFGILHFIYPFYKQKRFEWRFLLKQD"
     gene            34759..35679
                     /locus_tag="VCR92_000178"
     CDS             34759..35679
                     /locus_tag="VCR92_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407327.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEP4267277.1"
                     /translation="MKKRYQTLNEHYRQLFGAKMFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIKEQFYKEIDFMHRKWPDVNRYLVYFQNFTNTHDTVDVIRD
                     RYEQAINEPGVVGINIGTRPDCLPDDTIAYLAELSERMHVTVELGLQTTYEETSRLIN
                     RAHSYDLYKETVRRLRHYPNINIVSHLINGLPKETHDMMLENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLKLLSQKDYVSIICDQLEIIPKHIVIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDKEMERRGSFQGCKVD"
     gene            35718..36272
                     /locus_tag="VCR92_000179"
     CDS             35718..36272
                     /locus_tag="VCR92_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEP4267278.1"
                     /translation="MLKRPIHLSHDFLAEVVDKSSVVVDATMGNGNDTAFLAQLAKKV
                     YAFDVQEQAIRKTSERLAQLGLSNAELILAGHEAVDQYVTEPVRAAIFNLGYLPSADK
                     SIITLPNTTLQALSKLLTLLMVGGRIAIMVYYGHDGGSLEKDALLDFVKQLDQRKVSA
                     MLYQPLNQVNTPPFLIMLEKLADV"
     gene            36405..37739
                     /locus_tag="VCR92_000180"
     CDS             36405..37739
                     /locus_tag="VCR92_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEP4267279.1"
                     /translation="MEDPVSQPLVIQFLLLVVLTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKKYARLLRVLEEPNHFLSTIQVGITFISLLSGASLSASLGKVISGWLGNSATA
                     RTAGTIISLVFLTYVSIVLGELYPKRIAMNLKDKLAIVSAPIIIGLGRLVSPFVWLLS
                     ASTNLLSRLTPMTFDDADEQMTRDEIEYMLSKSEATLDAEEIEMLQGVFSLDEMMARE
                     VMVPRTDAFMIDINDDPLENIQEILKQSFSRIPVYDVDKDKIIGLIHTKRLLESGFRQ
                     GFDQINMRKMLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHEIGDNTYIVVGTMTLNEFNDYFDTELESDDVDTIAGFYLT
                     GIGTIPSQEQKEAYEIDNKDKHLVLINDKVKDGRITKLKLILSNIEQIIEED"
     gene            37817..38608
                     /gene="pflA"
                     /locus_tag="VCR92_000181"
     CDS             37817..38608
                     /gene="pflA"
                     /locus_tag="VCR92_000181"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEP4267280.1"
                     /translation="MTEKDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKLRCQYCH
                     NPDTWEMETNNSKIRTVNDVLKEALQYKHFWGKKGGITVSGGEAMLQIDFITALFIEA
                     KKLGIHTTLDTCGFTYRPTPEYHQVLDNLLAVTDLILLDLKEIDEKQHKIVTRQPNKN
                     ILQFARYLSDKQIPVWIRHVLVPGLTDIDDHLTRLGEFVKTLKNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVQNAKNLMQTESYTEYMNRIHQS"
     gene            38739..39674
                     /locus_tag="VCR92_000182"
     CDS             38739..39674
                     /locus_tag="VCR92_000182"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEP4267281.1"
                     /translation="MSKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPN
                     EETAFALDYFGVEAPRVVESAKAQGSEQVILTDHNEFQQSIADIREVEVYGVVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRMFKENGIEVPKAIAGMLLSGLISDTLLLKSPTT
                     HVSDHLVAEELAELAEVNLEDYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERQEAIEAAIKDAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKV
                     EAAFNFTLDNNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            39750..40403
                     /locus_tag="VCR92_000183"
     CDS             39750..40403
                     /locus_tag="VCR92_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEP4267282.1"
                     /translation="MITVFHSDKLTRQPFFQDLINYLDQHDHVILREIKKAFPNVTGI
                     DKAIESYVQAGYIRRENKRYGINLPLVSSDQQLALDTMLFVDTCSAMYENILAVVFET
                     QLTNQTNHVMIKEKTNITRDDLTLANYFYRLKRGEKPSAEQLDLYDLLGDVNQEYALK
                     YMTTFLLKFMRKDLVMQKRPDIFVEALVTLGYLKQVEPTTYQLLMTLDKESLTFIAP"
     gene            complement(40448..41485)
                     /locus_tag="VCR92_000184"
     CDS             complement(40448..41485)
                     /locus_tag="VCR92_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEP4267283.1"
                     /translation="MLFMVNKKRRPLLKSHRHLLGLYTSLILLLVSLMGLALSLGESH
                     LSFLDLIHVFLGKSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQRLTRNPLADS
                     GVLGITIGAGISLAIVVSFSFFEQAHISHYLPLFAMLGAVVTTFSVYWLSLTKQGQID
                     PTRLILTGVAVTTMLSSLMVALVGHINRYKVDLVINWLSGQLIGDDWPTLSVIAPLLL
                     CFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKRRLILVLAAGLGALSVLLVGNISFI
                     GLIAGHFSTYLVGSNHKITIPISILIGMILLLVADTVGRVYLVGTNIQTGILVSLIGA
                     PYFLYLMAKTK"
     gene            complement(41446..42459)
                     /locus_tag="VCR92_000185"
     CDS             complement(41446..42459)
                     /locus_tag="VCR92_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEP4267284.1"
                     /translation="MLKKTQIITKSHIFWLVFVLLSFSLCVAIYCHLRFGAVALSHQD
                     LNSILFGKQNGHKANVLLAIRLPRLFGATLTGSALAVSGTIMQAITRNPIAEPGLLGI
                     NAGAGLALVLAYAFVPHLHYSLIILLSLLGSSLAATLVFGLSYQSGKGYHQLRLVLAG
                     AMVSILLSALGQGITNYYHLANAVIGWQAGGLVGVNWQMIGYIAPLIILSLCLAQLLS
                     YHLTVLSLSESQAKALGQKTNLISAVFMILVLILSSAAVAIAGSISFIGLVIPHLMKH
                     FTPHHYRYLLPLCAVSGASFMVWVDIACRNLNPPYETPLGALVSLIGFPCFLWLIRRG
                     GRY"
     gene            complement(42487..43419)
                     /locus_tag="VCR92_000186"
     CDS             complement(42487..43419)
                     /locus_tag="VCR92_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEP4267285.1"
                     /translation="MKKLTLLLTLCLTTITLIACGNQATNHSNTASKSLSPMPQIAGV
                     TYYGDIPKQPKRVVSLASTYTGYLKKLDMNLVGVTSYDKKNPILAKTVKKAKQVAATD
                     LEAITTLKPDLIVVGSTEENIKQLAEIAPVISIEYRKRDYLQVLSDFGRIFNKEGKAK
                     KWLKDWKTKTAAYEKEVKAVTGDKATFTIMGLYEKDVYLFGKDWGRGGEVIHQAFHYD
                     APEKVKTEVFKQGYLSLSQEVLPDYIGDYVVVAAEDDKTGSALYESKLWQSIPAVKKH
                     HVIKVNANVFYFTDPLSLEYQLETLREAILSSEN"
     gene            complement(43445..44227)
                     /locus_tag="VCR92_000187"
     CDS             complement(43445..44227)
                     /locus_tag="VCR92_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4267286.1"
                     /translation="MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSS
                     LLKALTRLLPPKQGVVYLNGQNIATLETKEVAKKLALLPQVQEATNGITVYELVSYGR
                     FPHQSYFGNLSPADKKAIHWAMQATNVMAYADQPVDALSGGQRQRVWLAMALAQGTDT
                     IFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIVMVLHDLNLSARYSDHLIAMKHGKI
                     HYTGTIADVMTSPIIQDIFQIKPVLVDDPIHNCPIVLTYQLQ"
     gene            complement(44473..45918)
                     /locus_tag="VCR92_000188"
     CDS             complement(44473..45918)
                     /locus_tag="VCR92_000188"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEP4267287.1"
                     /translation="MITIEQLLDILKKDHNFREVLDADGYHYHYQGFSFERLSYDSRQ
                     VDGKTLFFAKGATFKADYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIAMV
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYHMLKESYKPAMFSTMNTTLDGKTFFKSQLT
                     TPESLDLFAMMAECVTNGMTHLIMEVSSQAYLVDRVYGLTFDVGVFLNISPDHIGPIE
                     HPTFEDYFYHKRLLMENSRAVVINSGMDHFSFLADQVADQEHVFYGPLSDNQITTSQA
                     FSFEAKGQLAGHYDIQLIGHFNQENAMAAGLACLRLGASLADIQKGIAKTRVPGRMEV
                     LTMTNHAKVFVDYAHNGDSLEKLLSVVEEHQTGKLMLILGAPGNKGESRRADFGRVIH
                     QHPNLTVILTADDPNFEDPEDISKEIASHIARPVEIISDREQAIQKAMSLCQGAKDAV
                     IIAGKGADAYQIVKGQQVAYAGDLAIARHYL"
     gene            46006..47640
                     /locus_tag="VCR92_000189"
     CDS             46006..47640
                     /locus_tag="VCR92_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEP4267288.1"
                     /translation="MSTEKKQLTQEELMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQTEHSYQLIRSTLKL
                     MLGLGLIFSAIMYLGSPLFASLSGGDDTLVPIMHSLSLAVFIFPVMSVIRGIFQGHNN
                     IKPYAISQIAEQLIRVIWMLLTTFLIMKLGSGDYASAVTQSTFAAFIGMVASMGVLGY
                     YLWKQGLLAAIFSKPDHTVSIDIKGLLLETLKESIPFIVTGSAIQAFQLIDQWTFVNT
                     MTLFTDYSRSQLLVLFGYFNANPAKITMVLIAVAASIGGVGIALLTENYVKKDMKAAA
                     RLIINNIEMLVMFLLPALTGAIILARPLYSVFYGASEDRAIHLFVAVLFQTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGILIKLVLQIPLIYLLHAYGPLLATTIALVVPIYLMY
                     RRLYQVTHFNRKLLQKRLLLTLIETLLMGLVVFVANWLLGYVFKPTGRLTSLLYLLII
                     GGLGMTVYTALTLLTHQLDKLIGSKASRLRQKLGWH"
     gene            47808..48437
                     /gene="upp"
                     /locus_tag="VCR92_000190"
     CDS             47808..48437
                     /gene="upp"
                     /locus_tag="VCR92_000190"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEP4267289.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQTTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVDIQTPVSKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDINQRQIFLVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDIDIFTAALDDHLNEHGYIVPGLGDAGDRLFGTK"
     gene            48661..49251
                     /locus_tag="VCR92_000191"
     CDS             48661..49251
                     /locus_tag="VCR92_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002274529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEP4267290.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLTYGFIDEIMENNELK"
     gene            49746..50021
                     /locus_tag="VCR92_000192"
     CDS             49746..50021
                     /locus_tag="VCR92_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEP4267291.1"
                     /translation="MFQKQERIGLVVYLYYNRDARKLSKFGDLYYHSKRSRYLIVYIN
                     KNDLDTKLEEMRRLKCVKDIRPSAFDDIDRQFVGNLHRDETNNHQKG"
     gene            50270..50905
                     /locus_tag="VCR92_000193"
     CDS             50270..50905
                     /locus_tag="VCR92_000193"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEP4267292.1"
                     /translation="MITGKLITVEGPDGAGKTTVLEQLIPLLKQKVAQEILTTREPGG
                     VAISEYIRELILDINHTTMDPKTELLLYIAARRQHLVEKVLPALEAGQLVFIDRFIDS
                     SVAYQGAGRGLIKADIQWLNEFATDGLEPDLTLYFDVPSEIGLARINANQQREVNRLD
                     LETIEIHQRVRKGYLALAKEHPKRIVTIDATKPLKEVVSVALEHVLALLLA"
     gene            50923..51798
                     /locus_tag="VCR92_000194"
     CDS             50923..51798
                     /locus_tag="VCR92_000194"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEP4267293.1"
                     /translation="MDLAQKAPNVYQAFQTILKKDRLNHAYLFSGDFANEEMALFLAK
                     VIFCEQKKDQTPCGHCRSCQLIEQGDFADVTVLEPTGQVIKTDVVKEMMANFSQTGYE
                     NKRQVFIIKDCDKMHVNAANSLLKYIEEPQGEAYIFLLTNDDNKVLPTIKSRTQVFQF
                     PKNEAYLYQLAQEKGLLNHQAKLVAKLATNTSHLERLLQTSKLLELITQAERFVSIWL
                     KDQLQAYLALNRLVQLATEKEEQDLVLTLLTLLLARERAQTPLTQLEAVYQARLMWQS
                     NVNFQNTLEYMVMSE"
     gene            52301..52624
                     /gene="yabA"
                     /locus_tag="VCR92_000195"
     CDS             52301..52624
                     /gene="yabA"
                     /locus_tag="VCR92_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEP4267294.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLE
                     NTKLRERLSHLEHETVAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            52629..53492
                     /gene="rsmI"
                     /locus_tag="VCR92_000196"
     CDS             52629..53492
                     /gene="rsmI"
                     /locus_tag="VCR92_000196"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEP4267295.1"
                     /translation="MQVQKSFKDKKTSGTLYLVPTPIGNLQDMTFRAVATLKEVDFIC
                     AEDTRNTGLLLKHFDIATKQISFHEHNAYEKIPDLIDLLISGRSLAQVSDAGMPSISD
                     PGHDLVKAAIDSDIAVVALPGASAGITALIASGLAPQPHVFYGFLPRKAGQQKAFFED
                     KHHYPETQMFYESPYRIKDTLTNMLACYGDRQVVLVRELTKLFEEYQRGSISEILSYL
                     EETPLKGECLLIVAGAQVDSEVELTADVDLVSLVQKEIQAGAKPNQAIKTIAKAYQVN
                     RQELYQQFHDL"
     gene            53519..53911
                     /locus_tag="VCR92_000197"
     CDS             53519..53911
                     /locus_tag="VCR92_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267296.1"
                     /translation="MTEDQATILILGVYGIILAVFLLSALLCLIANWRLFKRAGYKGW
                     YSLIPFYAGFVKHKITFGEDNKWFYFIGWVIAIYYYYVHFCYVRAFGGSKGLAVFGLF
                     FPGIASLIVAFGKTYTTQECHPVPHLLN"
     gene            complement(53958..54587)
                     /locus_tag="VCR92_000198"
     CDS             complement(53958..54587)
                     /locus_tag="VCR92_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEP4267297.1"
                     /translation="MIKEFCAENLTLLPTLDAGQVSRVELCDNLAVGGTTPSYGVIKE
                     ACQLLHDKKISVATMIRPRGGDFVYNDLELKAMEEDILKAVEAGSDALVLGLLTSENQ
                     LDTDAIEQLLPATQGLPLVFHMAFDRIPTDHQHQALDQLIDYGFVRVLTHGSPEATPI
                     TDNVEQLKSLVTYANKRIEIMIGGGVTAENCQSLSQLTGTAIVHGTKII"
     gene            54886..55242
                     /locus_tag="VCR92_000199"
     CDS             54886..55242
                     /locus_tag="VCR92_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEP4267298.1"
                     /translation="MITIYQYPKCSTCQRAMAELKQLVSDFEAIDIKANPPKAQDLKH
                     WMETSGYTIKNFFNTSGNSYRELGLKDKIDQLSLDKAAELLATDGMLIKRPILIKDGN
                     VLQVGYRKPYQELDLG"
     gene            complement(55316..56143)
                     /gene="xth"
                     /locus_tag="VCR92_000200"
     CDS             complement(55316..56143)
                     /gene="xth"
                     /locus_tag="VCR92_000200"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEP4267299.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHIETLLSYFPNYLHVWRSSVEPARKGYAGTMFLYKNTLNPVITFPEI
                     GAPTTMDAEGRIITLEFEDFFVTQVYTPNAGDGLRRLDDRQIWDHKYADYLTELDAQK
                     PVLATGDYNVAHKEIDLANPSSNRRSPGFTDEERQGFTNLLARGFTDTFRHLHGDIPH
                     VYTWWAQRSKTSKINNTGWRIDYWLASNRIVDKVKRSEMISSGERQDHTPILLDIDL"
     gene            56377..57558
                     /gene="lctO"
                     /locus_tag="VCR92_000201"
     CDS             56377..57558
                     /gene="lctO"
                     /locus_tag="VCR92_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEP4267300.1"
                     /translation="MAQKTVITEETTDFVMDFKTSSAEGNVDFINVFDLEKMAQQVIP
                     KGAFGYIASGAGDTFTLHENIRSFNHKLIVPHSLKGVENPSTEITFDGDHLTSPLILA
                     PVAAHKLANEQGEVASAKGLKEFGSIYTTSSYSTTDLPEISAALGGTPHWFQFYCSKD
                     DGINRNIMDRVKAQGCKAIVLTADATVGGNREVDRRNGFVFPVGMPIVQEYLPDGAGK
                     TMDYVYKSAKQALTSKDIEYIATYSGLPVYVKGPQCAEDTLRALDAGASGIWVTNHGG
                     RQLDGGPAAFDSLQEVAEAVDHKVPIVFDSGIRRGQHIFKALASGADLVALGRPAIYG
                     LAMGGSIGTRQVFEKLNDELKMVMQLAGTQTIQDVKAFNLRHNPYDSSIPFDQNALRL
                     D"
     gene            57824..62761
                     /gene="scpC"
                     /locus_tag="VCR92_000202"
     CDS             57824..62761
                     /gene="scpC"
                     /locus_tag="VCR92_000202"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CXC chemokine-degrading serine protease SpyCEP"
                     /protein_id="HEP4267301.1"
                     /translation="MEKKQRFSLRKYKSGTFSVLIGSVFLMMTTTVAADELTTTSEPT
                     ITNHAQQQAQHLTNTELSSAESQSPDTSQITPKINREKEQPQGLVSEPTTTELADTDA
                     APMANTGPDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQS
                     MRISDVSTAKVKSKEDMLARQKAAGINYGSWINDKVVFAHNYVENSDNIKENQFEDFD
                     EDWENFEFDAEPKAIKKHKIYRPQSTQAPKETVIKTEETDGSHDIDWTQTDDDTKYES
                     HGMHVTGIVAGNSKEAAATGERFLGIAPETQVMFMRVFANDVMGSAESLFIKAIEDAV
                     ALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVYGSDHDDPLA
                     TNPDYGLVGSPSTGRTPTSVAAINSKWVIQRLMTVKELENRADLNHGKAIYSESVDFK
                     DIKDSLGYDKSHQFAYVKESTDAGYNAQDVKGKIALIERDPNKTYDEMIALAKKHGAL
                     GVLIFNNKPGQSNRSMRLTANGMGIPSAFISHEFGKAMSQLNGNGTGSLEFDSVVSKA
                     PSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQIAGA
                     SLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGLLNIDG
                     AVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLSNKAKTLRYDTELLTDHVDPQKG
                     RFTLTSRSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTKQMPNGYYLEGFVRFRD
                     SQDDQLNRVNIPFVGFKGQFENLAVAEESIYRLKSQGKTGFYFDESGPKDDIYVGKHF
                     TGLVTLGSETNVSTKTISDNGLHTLGTFKNADGKFILEKNAQGNPVLAISPNGDNNQD
                     FAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNFNSDIRFAKSTTLLG
                     TAFSGKSLTGAELPDGYYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFDPET
                     NRFKPEPLKDRGLAGVRKDSVFYLERKDNKPYTVTINDSYKYVSVEDNKTFVERQADG
                     SFILPLDKAKLGDFYYMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDGNYQTKETL
                     KDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFVAFKGLK
                     NNVYNDLTVNVYAKDDHQKQTPIWSSQAGASASAIESTAWYGITARGSKVMPGDYQYV
                     VTYRDEHGKEHQKQYTISVNDKKPMITQGRFDTINGVDHFTPDKTKALGSSGIVREEV
                     FYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYTISKRDGVTLSDYYYLVEDRA
                     GNVSFATLRDLKAVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEYYNN
                     SGNSLILPYGKYTVELLTYDTNAAKLESDKIVSFTLSADNNFQQVTFKMTMLATSQIT
                     AHFDHLLPEGSRVSLKTAQGQLIPLEQSLYVPKAYGKTVQEGTYEVVVSLPKGYRIEG
                     NTKVNTLPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTASATPTKTTTSATAK
                     ALPSAGEKMGLKLRIVGLVLLGLTCVFSRKKSTKD"
     gene            63534..64241
                     /locus_tag="VCR92_000203"
     CDS             63534..64241
                     /locus_tag="VCR92_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEP4267302.1"
                     /translation="MSKKKRKHYQVYDGLRCAMTLCFISGYVNAFTYMTQGKRFAGVQ
                     TGNLLSFAIRLSEQQLKEALQFLLPMIVFMLGQSFTYFMHRWATKKGLHWYLLSSVIL
                     TGIAFGMALFTPFLPSNVTVAALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYEKNHELTHIGRNTLIVILAFAVGVVCSTLLCIAYGEYALMPILMPLLYVNYLL
                     AQEFYHIQTKIKPIKRT"
     gene            64481..66481
                     /gene="metG"
                     /locus_tag="VCR92_000204"
     CDS             64481..66481
                     /gene="metG"
                     /locus_tag="VCR92_000204"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEP4267303.1"
                     /translation="MMKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGHEV
                     FYLTGLDEHGQKIQTKAKEAGITPQTYVDNMAKDVKALWQLLDISYDTFIRTTDDYHE
                     EVVAAVFEKLLAQDDIYLGEYSGWYSVSDEEFFTESQLEEVFRDEDGKVIGGIAPSGH
                     QVEWVSEESYFLRLSKYADRLVAFFKERPDFIQPDGRMNEMVKNFIEPGLEDLAVSRT
                     TFTWGVPVPSDPKHVVYVWIDALLNYATALGYGQANHANFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDLPMPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERFGLDPLRY
                     YLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGTVPAYVDNGT
                     AFDADFSQLIDAQLADYHKHMEAVDYPRALEAIWTIIARTNKYIDETAPWVLAKEDGD
                     KAQLASVMAHLAASLRVVAHVIQPFMMETSAAIMAQLGLAPVSDLSTLALADFPANTK
                     VVAKGTPIFPRLDMEAEIDYIKAQMGDSSAISQEKEWVPEEVALKSEKDVITFETFDA
                     VEIRVAEVKEVSKVEGSEKLLRFRVDAGDGQDRQILSGIAKCYPNEQELVGKKLQIVA
                     NLKPRKMMKQYISQGMILSAEHGDQLTVLTVDSSVPNGSIIG"
     gene            66972..67985
                     /gene="nrdF"
                     /locus_tag="VCR92_000205"
     CDS             66972..67985
                     /gene="nrdF"
                     /locus_tag="VCR92_000205"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEP4267304.1"
                     /translation="MTQHYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQQLITRTYTGLTLLDTVQATVGDVAQIQHSQT
                     DHEQVIYTNFAFMVGIHARSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRSRVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVARLSPEKQAEMKAFVFDLLYELIDLEKAYLRELYAGFDLAEDAIRFSLYNA
                     GKFLQNLGYDSPFTDEETRISPEVFAQLSARADENHDFFSGNGSSYVMGITEETTDDD
                     WEF"
     gene            67989..68477
                     /gene="nrdI"
                     /locus_tag="VCR92_000206"
     CDS             67989..68477
                     /gene="nrdI"
                     /locus_tag="VCR92_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEP4267305.1"
                     /translation="MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYL
                     LIVPTYAAGGSDAKGAVPKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPIISQ
                     KLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQINNLITERTHPCHKPMRHT
                     SH"
     gene            68444..70624
                     /gene="nrdE"
                     /locus_tag="VCR92_000207"
     CDS             68444..70624
                     /gene="nrdE"
                     /locus_tag="VCR92_000207"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEP4267306.1"
                     /translation="MSQTNASYLSLNALTRFKKPDGSYHFDSDKEAVRRYLEEHVSPN
                     QMAFNSLEDKLAYLINEGYYEQAIFDAYPNDLIKEAFHYAYQQGYRFLNLMGAMKFYQ
                     SYALKTLDGKQYLETFEDRAVMNALFLADGDQTFVFDVIDAILHRRFQPATPTFLNAG
                     KKRRGEYISCYLLRVEDNMESISRAISTSLQLSKRGGGVALCLTNLREIGAPIKGIEN
                     QATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLHAHHPEVLTFLDTKRENADEKIRIK
                     SLALGLVIPDITFQLAKENKDMALFSPYDIKRAYGKDMSDISITEEYDKLLANPAIKK
                     TYISARKFFQLIAELHFESGYPYLLFDDTVNKRNPHAKKGRIVMSNLCSEIAQVSTPS
                     TFKEDLSFETIGEDICCNLGSINIAQAMADAPHFEQLITTSIRALDRVSRVSDLNCAP
                     SVETGNAANHAVGLGAMNLHGFLATNHIYYDTKEAVDFTDLFFHAMAYYAFKASCQLA
                     KEKGAFAGFSLSTYADGTYFAKYLQEDAKPQTAKVATLLQDYGFTLPTVADWQALVAD
                     IKQFGLANAHLLAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGSLGRIYVPAYQIDQA
                     NYAYYERGAYEVGPKAIIDVVAAAQKHVDQAISLTLFMTDQATTRDLNRSYIQAFKQN
                     CASIYYVRVRQDVLAGSEQYDEDSLVTAPGASDETTTECQSCMI"
     gene            complement(70829..71581)
                     /locus_tag="VCR92_000208"
     CDS             complement(70829..71581)
                     /locus_tag="VCR92_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEP4267307.1"
                     /translation="MLKKRYQLAMILLLSCFSLVWQTEGLVELFVCEHYERAVCEGTP
                     AYFTFSDQKGAETLIKKRWGKGLVYPRAEQEAMAAYTCQQAAPINTSLDKTKGELSQL
                     TPELRDQVAQLDAATHRLVIPWNIVVYRYVYETFLRDIGVSHADLTSYYRNHQFDPHI
                     LCKIKLGTRYTKHSFMSTTALKNGAMTHRPVEVRICVKKGAKAAFVEPYSAVPSEVEL
                     LFPRGCQLEVVGAYVSQDQKKLHIEAYFKGSL"
     gene            72038..72619
                     /locus_tag="VCR92_000209"
     CDS             72038..72619
                     /locus_tag="VCR92_000209"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267308.1"
                     /translation="MKTKSKRFLNLATLCLALLGTTLLMTRPVKADNDTRESQERVDQ
                     RIEDPYDDGKNAGRKDGYESGNHKGISEEPPTKTPEPPTNPYSRDRVKSKKYRDGYQE
                     WYVYGYYEGWHRANDEDKNKESSDHSRDQDLEGTEQTDGQDEDKNKESSDHSRNQDLE
                     GTEQTDTEYSAIISTLYGIAGVVLEYVLSWFSI"
     gene            73279..73515
                     /locus_tag="VCR92_000210"
     CDS             73279..73515
                     /locus_tag="VCR92_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018364244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEP4267309.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTLEVDGKVLQAT
                     PYFLIHVTGEGEGFSMWAPTPCDVLAEDWIEVND"
     gene            73508..74206
                     /locus_tag="VCR92_000211"
     CDS             73508..74206
                     /locus_tag="VCR92_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEP4267310.1"
                     /translation="MTKVVLVTGCASGIGYAQARYFLRQGYHVYGVDKSDKPDLSGNF
                     HFIKLDLSSELSPLFKVVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFATVK
                     LTRHYLRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQI
                     HIFGIAPGAVKTAMTASDFEPGGLAEWVARETPIGRWTEPDEVAELTGFLASGKARSM
                     QGEIVKIDGGWTLK"
     gene            74282..75241
                     /locus_tag="VCR92_000212"
     CDS             74282..75241
                     /locus_tag="VCR92_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEP4267311.1"
                     /translation="MKLAVLGTGMIVKEVLPVLQKIDGIDLVAILSTVRSLKTAKDLA
                     KAYHMPLATSEYEAVLGNEEIDTVYIGLPNHLHFAYAKEALLAGKHVICEKPFTMTAG
                     ELDELVVIAKKRKLILLEAITNQYLNNMTFIKEHLDQLGDIKIVECNYSQYSSRYDVF
                     KRGDIAPAFNPKMGGGALRDLNIYNIHFVVGLFGRPKTVQYLANVEKGIDTSGMLVMD
                     YEQFKVVCIGAKDCTAEIKTTIQGNKGSLAVLGATNTLPQVQLSLHGHEAQVVNHNKY
                     DHRMYEEFVAFRDMIDQRDFEKVNQALEHSRAVMAVLERAVHS"
     gene            75574..76911
                     /locus_tag="VCR92_000213"
     CDS             75574..76911
                     /locus_tag="VCR92_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP4267312.1"
                     /translation="MEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLM
                     SNTIMVQNGWDKAQIATLLSCLTVSYGLAKFYMGALGDRVSLRKLFSISLGASALICI
                     LIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGS
                     ALLPLTIALLTSMGLVVPANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLR
                     TMYGDAGESAVASEEEKHNLSYWQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMP
                     IYLSQVANMSEAHIHFAISMLEWVAIPGSLVFAWLAVRYPNKMAKIGAIGLFVLAAIV
                     FVYERLTATGAPNYFLLLVIAGILGSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVT
                     AYLIGNMGANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD"
     gene            77084..78466
                     /gene="glmU"
                     /locus_tag="VCR92_000214"
     CDS             77084..78466
                     /gene="glmU"
                     /locus_tag="VCR92_000214"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEP4267313.1"
                     /translation="MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAIS
                     PEKSVTVIGHKSEMVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIAGD
                     TPLITGESLKSLIDFHVNHKNVATILTATAQDPFGYGRIVRNKDGEVIKIVEQKDANE
                     YEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTDVVTIFRANKEKVGAYILR
                     DFNESLGVNDRVALATAETVMRQRITQKHMVNGVTFQNPETVYIESDVEIAPDVLIEG
                     NVTLKGRTHIGSGTVLTNGTYIVDSEIGDNCVVTNSMIESSVLAAGVTVGPYAHLRPG
                     TTLDREVHIGNFVEVKGSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKY
                     ETVIGDHAFIGSNSTLIAPLEVGDHALTAAGSTISKTVPIDSIAIGRSRQVTKEGYAK
                     RLAHHPSRSK"
     gene            78497..79051
                     /locus_tag="VCR92_000215"
     CDS             78497..79051
                     /locus_tag="VCR92_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEP4267314.1"
                     /translation="MKFEEKTLKRQTVFDGHIFKVVVDDVELPNNLGQSKRELIFHRG
                     AVAVLAITPERKILLVKQYRKAIERVSYEIPAGKLEIGEEGSKLKAAARELEEETAYT
                     GTLTFLYEFYTAIGFCNEKITLFLATDLTQVANPKPQDDDEVIEVLELTYQECMDLVA
                     QGKLADAKTLIALQYYALHFGGEQ"
     gene            79051..79302
                     /locus_tag="VCR92_000216"
     CDS             79051..79302
                     /locus_tag="VCR92_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267315.1"
                     /translation="MGRPLLTDDIIEKARRMETFESDDAVDFDTKVMTLPEKDDKARI
                     YKSRRIENAKRSQLQSKLNVILIAVMLLIAILVYAIFYL"
     gene            79322..80017
                     /locus_tag="VCR92_000217"
     CDS             79322..80017
                     /locus_tag="VCR92_000217"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEP4267316.1"
                     /translation="MKIGIIAAMEEELSLLLANLLDAQEHQVLSKTYYTGRFGKHELI
                     LVQSGVGKVMSAMTVAILVEHFKAQAIINTGSAGAVASHLAIGDVVVADRLVYHDVDA
                     TAFGYAYGQMAGQPLYYDCDPQFVAIFKQVLKHEKTNGQVGLIATGDSFVAGQDKIDQ
                     IKTAFSDVLAVEMEGAAIAQAAHTAGKPFIVVRAMSDTAAHDANITFDQFIIEAGKRS
                     AQILMTFLENLPV"
     gene            80168..80509
                     /locus_tag="VCR92_000218"
     CDS             80168..80509
                     /locus_tag="VCR92_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267317.1"
                     /translation="MTLKKHYYLLSLLALVTVGAAFNTSQSVSAQVYSNGRYRQGLTD
                     EKSKLQYSKDNAKLQLRNILNGYQSDLGRHYSSYYYYNLRTVMGLSKEQEIEKYYEEL
                     KNKLHDMYNHY"
     gene            complement(80608..81255)
                     /locus_tag="VCR92_000219"
     CDS             complement(80608..81255)
                     /locus_tag="VCR92_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEP4267318.1"
                     /translation="MTPNKEDYLKCIYEIGEQEPKITNKMVAEKMHVSAPAVSEMIKK
                     MISQGWIVKDKAKGYLLKDKGYALVANLYRKHRLIEVFLIHQLGYNTQEVHQEAEVLE
                     HTVSDTFIDRLDKILDFPDFCPHGGTIPRYGQPLVEMNTTTLNTITELGRFRLSRIHD
                     HFDLIQYLEAHHLSINTELTLTQIDTFAKTYTICYGDKELVIPENIAKQLYVTAL"
     gene            81400..82332
                     /locus_tag="VCR92_000220"
     CDS             81400..82332
                     /locus_tag="VCR92_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_101244918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEP4267319.1"
                     /translation="MGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIA
                     DMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADVIFYNGINLEDGGQAWFT
                     KLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLI
                     AKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYS
                     EIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK"
     gene            82396..83121
                     /locus_tag="VCR92_000221"
     CDS             82396..83121
                     /locus_tag="VCR92_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004218966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEP4267320.1"
                     /translation="MITTNNLCVTYDGNSNALEAINVTIEGPSIVGIIGPNGAGKSTF
                     MKAILNLIDYQGHVTVDGKDGRKLGHTVAYVEQRSMIDYNFPITVKECVALGTYSKLG
                     LFRRVGKKQFEQVDKVLKQVGLEDFGHRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIVDLLKELKMAGKTILIVHHDLSKVEHYFDKLMILNKHLVAYGNVC
                     EVFTVDTLSKAYGNHLILGKEMV"
     gene            83122..83976
                     /locus_tag="VCR92_000222"
     CDS             83122..83976
                     /locus_tag="VCR92_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEP4267321.1"
                     /translation="MSMKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGVNFFIGAIIFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDSDKWITIGVSIFVLVVISLFFKELLLT
                     SFDPILAKSMGVKVNAYHYLLMVLLTLVAVTAMQSVGTILIVALLITPAATAYLYANS
                     LKVMLVMSSLLGALASVLGLYLGYTFNVAAGSSIVLTSAMMFLISFFVSPKQGYLKRW
                     MQKKEKTP"
     gene            complement(84123..84929)
                     /locus_tag="VCR92_000223"
     CDS             complement(84123..84929)
                     /locus_tag="VCR92_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEP4267322.1"
                     /translation="MKKLLSLSLVAISLLSLSACESVDRAIKGDKYIDEKTAKEESEA
                     ASKAYEESIQKALKADASQFPQLTKEVGKEEAKVVMRTSQGDITLKLFPKYAPLAVEN
                     FLTHAKKGYYDNLTFHRVINDFMIQSGDPKGDGTGGESIWKGKDPKKDAGNGFVNEIS
                     PFLYHIRGALAMANAGANTNGSQFYINQNKKNQSKGLSSTNYPKPIISAYEHGGNPSL
                     DGGYTVFGQVIDGMDVVDKIAATSINQNDKPKQDITITSIDIVKDYRFKN"
     gene            85146..87551
                     /locus_tag="VCR92_000224"
     CDS             85146..87551
                     /locus_tag="VCR92_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEP4267323.1"
                     /translation="MVKRNQRRKSAPKKCLTKAEVEKQRAIKRMILSVLMALLLIFAM
                     LRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCFKWLRQKDGMIAGVVIAFLGLLV
                     EWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKEAVDKLAVAYQENKEKRFIKREEHRLQA
                     EKEALEKQAQEEEKRLAELTVDPETGEIVEDSQSQVSYDLAEDMPKEPEILAYDSHLK
                     DDEASLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVDVDFTPKTHLLYKLPTI
                     DLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGV
                     RVNRISNLADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANP
                     ENLLEVPLGKAVNGNARSFNLARMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQVK
                     FLMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKVGVRNIA
                     GYNAKVEDYNRQSEQKQMPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIH
                     MILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPI
                     DENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFDPGEVSDNDPGFSGNGGAAEG
                     DPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVL
                     QTN"
     gene            complement(87621..87974)
                     /locus_tag="VCR92_000225"
     CDS             complement(87621..87974)
                     /locus_tag="VCR92_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEP4267324.1"
                     /translation="MMIYKLTALAFLIVTPLFAMIVTPLFKLNKKGFKFPDVALLLFA
                     IEIVLVSGKFFTHNLLPYYLIIMSLLAIVISLLLVIRTQSFSYHRFMKLFWRVGFLVT
                     VIFYLILVIFIFTLA"
     gene            88218..88643
                     /gene="rplK"
                     /locus_tag="VCR92_000226"
     CDS             88218..88643
                     /gene="rplK"
                     /locus_tag="VCR92_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEP4267325.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNTTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            88749..89438
                     /gene="rplA"
                     /locus_tag="VCR92_000227"
     CDS             88749..89438
                     /gene="rplA"
                     /locus_tag="VCR92_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEP4267326.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALVKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMANVSITSTQ
                     GVGIKVDPNSL"
     gene            89760..90488
                     /locus_tag="VCR92_000228"
     CDS             89760..90488
                     /locus_tag="VCR92_000228"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEP4267327.1"
                     /translation="MEPKYQRILIKLSGEALAGEKGVGIDIPTVQAIAKEIAEVHVSG
                     VQIALVIGGGNLWRGEPAADAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKNRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPKKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIQRVVFGEHIGTTVSNKVCD"
     gene            90517..91074
                     /gene="frr"
                     /locus_tag="VCR92_000229"
     CDS             90517..91074
                     /gene="frr"
                     /locus_tag="VCR92_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEP4267328.1"
                     /translation="MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAIKEIDRMTAEKEKELLSV"
     gene            91183..92040
                     /locus_tag="VCR92_000230"
     CDS             91183..92040
                     /locus_tag="VCR92_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEP4267329.1"
                     /translation="MNDLLATVITGLIKEENANDYFIQKEGFTFTLSKAEGERQIGDM
                     VTGFAYTDIKQKARLTTKEIRSTRTSYGWGEVTEVRRDLGVFVDTGIPNKEIVVSLDV
                     LPEMKELWPKKGDKLYIRLDVDKKDRIWGLPAEPEVFQKMASPAYNNMQNQHWPAIVY
                     RLKLTGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMIVTYLEANGGFMTLNDKSSPEEIKATFGISKGQFKKALGGLMKAKRIKQ
                     DATGTELIG"
     gene            92113..92622
                     /gene="msrA"
                     /locus_tag="VCR92_000231"
     CDS             92113..92622
                     /gene="msrA"
                     /locus_tag="VCR92_000231"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEP4267330.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHLPNPSYEQV
                     CAKTTGHTEAVEIIFDPEEISYKELVELYWVQTDPTDAFGQFEDRGDNYRPVIYYTTE
                     RQKEIAEQSKANLQASGRFDQPIVTTIEPAEPFYLAEDYHQGFYKKNPRRYAQSSAIR
                     HQFLEENWS"
     gene            92619..92834
                     /locus_tag="VCR92_000232"
     CDS             92619..92834
                     /locus_tag="VCR92_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEP4267331.1"
                     /translation="MRKSFYSWLMTQRNPKSNAPVAILADLVFDDTTFPKHTNDFELI
                     SRYLEDQASFSFNLGQFDEIWEDYLAH"
     gene            92990..94171
                     /locus_tag="VCR92_000233"
     CDS             92990..94171
                     /locus_tag="VCR92_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEP4267332.1"
                     /translation="MIITKKSLFVTSVALSLAPLATAQAQEWTPRSVTQIKSELVLVD
                     NVFTYTVKYGDTLSTIAEAMGIDVHVLGDINHIANIDLIFPDTILTANYNQHGQATTL
                     TVQAPASSPASVSHVPSSEPLPQASATSQSTIPMAPSATPSDVPTTPLASAKPDSFVT
                     ASSELTSSTNDVSTELSSESQKQPEVPQEAVPTPKAAETTEVEPKTDISEDSTSANRP
                     VPNESASEEASSAAPAQAPAEKEETSQMLTAPAAQKAVADTTSVATSNGLSYAPNHAY
                     NPMNAGLQPQTAAFKEEVASAFGITSFSGYRPGDPGDHGKGLAIDFMVPVSSTLGDQV
                     AQYAIDHMAERGISYVIWKQRFYAPFASIYGPAYTWNPMPDRGSITENHYDHVHVSFN
                     A"
     gene            94486..96258
                     /locus_tag="VCR92_000234"
     CDS             94486..96258
                     /locus_tag="VCR92_000234"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HEP4267333.1"
                     /translation="MYYTSGNYEAFATPRKPEGVDQKSAYIVGTGLAGLAAAVFLIRD
                     GHMAGERIHLFEELPLAGGSLDGIEKPHLGFVTRGGREMENHFECMWDMYRSIPSLEI
                     PGASYLDEFYWLDKDDPNSSNCRLIHKRGNRVDDDGQYTLGKQSKELVHLIMKTEESL
                     GDQTIEEFFSEDFFKSNFWIYWATMFAFEKWHSAVEMRRYAMRFIHHIDGLPDFTSLK
                     FNKYNQYDSMVKPIIAYLESHDVDIQFDTKVTDIQVEQTAGKKVAKTIHMTVSGEAKA
                     IELTPDDLVFVTNGSITESSTYGSHHEVAKPTKALGGSWNLWENLAAQSDDFGHPKVF
                     YQDLPAESWFVSATATIKHPAIEPYIERLTHRDLHDGKVNTGGIITITDSNWMMSFAI
                     HRQPHFKEQKDNETTVWIYGLYSNSEGNYVHKKIEECTGQEITEEWLYHLGVPVDKIK
                     DLASQDYINTVPVYMPYITSYFMPRVKGDRPKVIPDGSVNLAFIGNFAESPSRDTVFT
                     TEYSIRTAMEAVYSFLNVERGIPEVFNSAYDIRELLKAFYYLNDKKAIKDMDLPIPAL
                     IEKIGHKKIKDTFIEELLKDANLM"
     gene            96417..97469
                     /locus_tag="VCR92_000235"
     CDS             96417..97469
                     /locus_tag="VCR92_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEP4267334.1"
                     /translation="MQEYSIDITLTHPDDVLALFGSNERHLKLIEAHLGVIVHARTER
                     VQVIGDDEEAVELARLTIKALLVLVGRGMVVNTSDVVTALSMAESHQIDQFMALYEEE
                     IIKDNYGKAIRVKTLGQKTYVDSVKRHDVVFGVGPAGTGKTFLAVTLAVTALKRGQVK
                     RIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYHILGKEQTTRLMERDVIEIA
                     PLAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFNSKMIVNGDTSQIDLPRNVKS
                     GLIDATQKLQGIKQIDFVYFSAKDVVRHPVVADIIKAYETSSEEMKDLLKPKASDVEA
                     DYQPGLTKYPVIGQEH"
     gene            97515..98090
                     /locus_tag="VCR92_000236"
     CDS             97515..98090
                     /locus_tag="VCR92_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEP4267335.1"
                     /translation="MDDLTKAIMADEANLSYTERGIFPLYDAPQTARLIIVGQAPGIV
                     AQETKLYWNDRSGIRLRDWLGVDNDTFYHSGLFGIIPMDFYYPGKGKSGDLPPREGFA
                     AKWHPPLRALMPEVELTILVGRYAQDFYLGNKAYKTLTETVRHFEDYLPDYFPLVHPS
                     PRNQLWLAKNPWFEQDLLPILQKRVEAILTK"
     gene            98249..98746
                     /gene="ybeY"
                     /locus_tag="VCR92_000237"
     CDS             98249..98746
                     /gene="ybeY"
                     /locus_tag="VCR92_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEP4267336.1"
                     /translation="MYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGKEEKEMSVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDFAADPSLAEMMAEFDAYIGEL
                     FISIDKAREQSQEYGHSFEREMGFLAVHGFLHINGYDHYTLEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            98727..99134
                     /locus_tag="VCR92_000238"
     CDS             98727..99134
                     /locus_tag="VCR92_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEP4267337.1"
                     /translation="MALHDNNTTKRKWKNRTITSSLEFALTGVFTAFKEERNLRSHLL
                     SACLACVAGLFFSISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKNA
                     KDMAAGAVLMISGYAVLTGLIIFIPKIWNIFVH"
     gene            99254..100150
                     /gene="era"
                     /locus_tag="VCR92_000239"
     CDS             99254..100150
                     /gene="era"
                     /locus_tag="VCR92_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEP4267338.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTL
                     IKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKR
                     DEETDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNEKEY"
     gene            100170..100646
                     /locus_tag="VCR92_000240"
     CDS             100170..100646
                     /locus_tag="VCR92_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEP4267339.1"
                     /translation="MPQDYISYIRSKVGHDKIILNFAGGILTNDDGKVLMQLRGDKKT
                     WAIPGGTMELGESSLETCKREFLEETGIEVEAVRLLNVYTHFEEVYPNGDAVQTIVFI
                     YELTAVSDMAIDNFHNEETLKLQFFSHEEIAELESVSAKHRLMLEEYFSDSFAMGH"
     gene            complement(100952..101131)
                     /locus_tag="VCR92_000241"
     CDS             complement(100952..101131)
                     /locus_tag="VCR92_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267340.1"
                     /translation="MRYPHAHIILIGNHINYEEIFKNHYRVFGVIDTTSHKSLKSIRD
                     QIQLYLDELYNSNNG"
BASE COUNT        31730 a        18435 c        21232 g        29781 t
ORIGIN      
        1 ttaattatat tatgtgtcaa aataacaaca aaggttatta tatctaagat tacttcgata
       61 gtcaatagaa attgactgaa aattcttagc acaaaaaatg gttaagatat gtagctcatt
      121 cgatttgacg aatagataga attatattat tataaaaaac atgtaacttt agtaaggatg
      181 taacgtatga aaaaaatata tgatttatgg gttagggtta gtctaatcaa aaaaataggt
      241 atcggtgttg taataggagt catgttgggc attttggctc ctgatcttac aggttttagt
      301 attttaggaa agttatttgt tggtggttta aaggctatcg cacctttgct tgtatttgct
      361 ttggtttccc aagccatctc ccatcagaaa aaagggaaac agactaatat gacattaatc
      421 attgttctgt atttatttgg tacctttgcg tcagctttag tagcagtact gacagcttat
      481 ctattccctt tgacgttagt gttaaataca cctgtaaata cagaattatc accacctcaa
      541 ggtgttgctg aagtttttca gtcacttcta ttaaaattag tggataatcc gatcaatgct
      601 ttagctactg ccaattatat tggtgtgcta tcatgggcaa ttatttttgg actagcatta
      661 aaggctgcaa gtcaagaaac aaagcatctt ataaaaacag cggcagaagt tacttcacaa
      721 atagttgttt ggatcatcaa tctggcacct attgggatta tgagtctggt gttcactacg
      781 atttctgaaa acggtgttgg aatcttatct gattatgctt ttttgatact agttttagta
      841 ggaacaatgg tttttgtcgc cttagtggtt aatccactta ttgcggtttt gattacacga
      901 caaaatcctt atccccttgt cttgagatgt ttacgtgagt caggtcttac agcatttttc
      961 acacgaagtt ctgcagccaa tattccagtc aatatgcaat tatgccaaaa aattggattg
     1021 agtaaagata cttattcagt gtcaattcca cttggagcaa ctattaatat gggtggggca
     1081 gcaattacca tcaatgtcct aacgcttgct gctgtacaca cttttggtat tcctattgat
     1141 tttctaacag ccctcttact tagcgttgtt gctgctgtct ctgcttgtgg tgcttctggt
     1201 gttgctgggg gatcgttgtt acttattcct gtagcatgta gtttgtttgg catctcaaat
     1261 gatcttgcga tgcaggtggt tggtgttggt tttattgttg gtgttatcca ggattcttgt
     1321 gagacagcct taaattcgtc aaccgatgtt ctttttacag ctattgctga aaatgctttt
     1381 tggaaacgta aaaaagccta gctaggttta acatagtaaa aaacatcctt ggaaaacgcc
     1441 aaggatgttt ttttattatt taagatagcc aagataatca aatttttcaa aggtgtggtc
     1501 attagcgatg gctacaatga tagtattcgg ttctaaaggt tcaaaaggtt tgacattggt
     1561 atctaaggtt ttaacttctt tttgacgcat gccaatcaca tttaactcat atttacgacg
     1621 aacatctagt tcggaaagag attgtccttc ccagctttta ggaatgacaa attcaatcat
     1681 ggaaatgcca tgttcgaggt agatgatgct ttcgatatga cgtcttaaca gatttgaagc
     1741 tacacgtttt ccagaatcac gttcaggggt gatgacttta gttgccccga tgccatatag
     1801 aacttcttca aaaattttat ttttagcctt ggcaataatg gttggaacac cgagtttttt
     1861 acagtgcatg actgcaagaa cagaagattc caagttattc cctgaagcga taacgacagt
     1921 atcacaatgt tcaatcccta cagctaatag aaattctttg tcagtaatat ctccaacagc
     1981 ggctttagtg accaagtcgg ccacctcttt aacatgactt tctctgatat caatagcaat
     2041 aacgtcttga tcaaaattac ttaattctct ggcaacagta cggccaaaaa taccaaggcc
     2101 aagaacgccg acagttttac gttttaacat gttttctcct taacccacta aaatatcagt
     2161 agtggcatat tgaatggttt tttcttttcg ttgaatcaga ctgatgagga cagtaattgg
     2221 gccaacgcgg ccgacgaaca tcaagacaat gacaataaga cgtccagcag tagacaattg
     2281 tggtgtcaaa tccatagata ccccaactgt cgcgatggca gaaatagatt caaataagag
     2341 tggtatagga gcgatatgag gctccacgct aagtaataaa ataaaaccta tcataagaac
     2401 tgcaaaaaag aagataagaa ctgtcatggt ctgcttaatt gtcttatttg cgataattcg
     2461 gttacgaaag gtaacttctg attgccctga aagttccgct ttaaagagta agaaagtaat
     2521 ggcagcagtc gtcactttaa taccaccagc tgttccacca ggagcaccac caataaccat
     2581 ttgaatcata taaagaatgt tagtcggtgc tagggtatcg ttataagaga ttgttgcaaa
     2641 gccagctgtt ctcatagtga ctgtttgaaa aaatgaaacc ataagttgct gatgtaaact
     2701 aaaattggca atggttttgc tgttatcttt ttctaaaaac caggttaaga aggttccaag
     2761 aaaaagaata acagctgtgg tttgtagtac tagacgagac tgattggata atttacgaaa
     2821 agttgcccca taacaatgag gtctttcaaa aaagtatttt ttaaaagcta ctcctaaatc
     2881 aacccaaacc gcaaaaccaa gtccaccaga gataatcaag aacgtaatga taacatttaa
     2941 tgtaggattt aacataaagt cttttaaact agaagatcct aaattgtcaa aaccagcgtt
     3001 acaaaatgcc gacacagcta gaaaaatact attgaagata ccatttttcc acccgaagcg
     3061 ggggataaag tcaatcatga taactatcgc agcaaaggct tctatactaa aggttacttt
     3121 ataagcaaaa aaaaggtagt gctttaaatc tttgctatca cctcgattta acgctgattg
     3181 gagcaaggtt tgatcgctca atcgcatttt tcgcttgagg gcaaaagtac tcacagctat
     3241 taacgtcacc aagccaagac caccaatctg cattagtgcc atagcaatgg tttgtccgat
     3301 accgttatac acttcagcga cgggaacaac agaaagtcca gtcacacaaa ccatggaaac
     3361 cacattaaag aaatgatcaa gatagacggt attaggacca ttttgataat gggtaaaggg
     3421 catggataac aagagagtcc caatcagaat cacaatggca aaactaaatg ttaagcgctg
     3481 tgtgactgaa agagatttga taaaagagcg tttcatgttt cctccagaca taatatctcc
     3541 tactataata acaaaaataa gttaaaaaag ctaagtttca tcttagcctt tggtactatt
     3601 ttatagaggt tttttgttag gcaagccagc ttttcttgga tacttgttag gtgtttcctt
     3661 tttcttctca acaatggtga tgaagcgaga atctccattt ggcaattggt agctatggtt
     3721 tttaatgact ttaccaaaaa gaagacaaag agcattctta gcttcttcta actcttggtc
     3781 agcagcttgt gcctttaagg cgattaattt tcctccaatt tttaaaaagg ggatggttaa
     3841 ttcagataga acctgcatcc gagcaaccgc tctggcagta acgacatcaa attgacctcg
     3901 aaaggccttg tcctgtccga aatcttctgc tctaccatga aaaaaatgga cattttccaa
     3961 gcccaattcc tgagcaagga gtgtcagaaa agaaatccgc ttattaagag aatcaataat
     4021 ggtaacctca aggttcggga aaagaatttt catgggtagg ctaggaaaac cagctccagc
     4081 tccaatgtcc aataatttga ttggttcatt agctaaaaag ccctgtaaaa taggagcgat
     4141 ggaatcataa aaatgcttga ggtaaacctc attttcttct gtaatagctg ttaaattaat
     4201 tttagtgttc cattccacta gtaatttaaa gtaggtgtca aattgttctt tttgtttcga
     4261 tgataaggaa aaaccatctt cctctagtgt tcggtaaaag tcttggggtg tcatttgtat
     4321 cctctgtttt tgatagttgt taccatttta tcataaaata gcccataaca aaatccaata
     4381 aatcatcaga aataacacct cattacttgc tattagccta gaaattgcta taattgagac
     4441 acaaagatta aaggagaccc actatgccaa cagttttgat tatcttagtc gttttaggag
     4501 tgcttgcgct atggttaatg attagttaca atagcctggt taaatctcgg atgcacacaa
     4561 aagaagcttg gagtcagatt gatgtgcaat taaagcgtcg taatgacttg attccaaatc
     4621 ttattgaaac cgtaaaggga tatgctagct acgagcaaaa gacatttgaa aaaatcactg
     4681 atttgcgtgc gcgtgttgcg aatgcctcaa ctcctcaaga aaccatggcg gcttctaacg
     4741 aattgagtaa acaagtgacc agtttgtttg ccgttgctga aaattaccca gacttaaaag
     4801 ctaacgaaaa cttcttgaaa ttacaagaag agttgaccaa tacggaaaat aaaatctcat
     4861 attctcgtca actctataat tcaacaacgt ctaattacaa ccttcaatta gaatctttcc
     4921 caagcaatat cgctggtaaa ttatttggtt ttaaaccaag tgaattctta caaacaccag
     4981 aagctgaaaa agaagttcca aaagttgaat ttaactttta aatatgaaat tatcatctag
     5041 taggcaatca taagagaaag gagaattatg ctttatcaac agatttcaca aaataagcaa
     5101 cgaacagttg ttttattagt tgttttcttc gctctcttag cacttattgg agcttcagca
     5161 ggctatctgc tgttagataa ttatgccatg ggcttggttc ttgctcttgt cattggggtg
     5221 atttatgcta ccagtatgat ttttcaatcc accagtcttg taatgagtat gaacaatgct
     5281 agagaagtca cagaaaaaga ggctccaggc ttcttccata ttgtcgagga tatggctatg
     5341 gtggctcaga ttccgatgcc gagagttttt attattgaag atccttcttt aaatgctttt
     5401 gcgacaggat ctagccctca aaatgctgct gttgcagcaa cgacaggttt acttgaagtc
     5461 atgaatcgtg aagaacttga aggtgttatc ggccatgaaa ttagccacat ccgaaattat
     5521 gatatccgta tttcgactat tgctgtagct ttggcgagtg ctgttaccgt tatttctagt
     5581 atcggtgggc gtatgctatg gtatggtggc ggttctcgca ggcaaagaga tgacggagat
     5641 gatgatgttt taagaatcat tacattactt ttgtcgttat tatctttgct tttagcgccc
     5701 ctagtagcaa gtttgattca gttggctatt tctcgtcaaa gagaatatct agctgatgct
     5761 agttctgttg aactaacaag aaatccccaa ggtatgatta acgctcttga aaaattgcag
     5821 ttatctcagc caatgaagca tcctgttgat gatgctagtg cagccttgta tattaatgag
     5881 cctcgcaaaa aaaggagctt cagttcatta ttcagcaccc atcctcctat tgaggagagg
     5941 attgaaaggc taaaaaacat gtgagcgttt ggggtttttg ctcaaacctc acttttttat
     6001 gtctttgggc agataatcta aaatggcagg aattatcaaa aatatctgaa caaaaagaaa
     6061 aaaatgagtg aaacaatggt taaaaataga atgatttaaa tcttaaaatt aaaaaacgtc
     6121 agaaaataaa tgcaaaacta ttgacaaatc ttttagatag tagtaaaaat aaatgagagt
     6181 tttattagga gaagatgatg ttagctattt ccgaaatcag aaaacaccca gacggtctct
     6241 cgtttgatcg tttatgtgat gtcaaaagta tgttacttga gcgtgaccaa cagattattg
     6301 acataaaggc agttaaagct gtcggtaatg ttcgctatga taaggggctt tatctgttag
     6361 attatcaatt gagttacgaa gtgatattac cgtctagccg ttctatggtt ccggtctgtt
     6421 taagtgaagt ccaacacatt caagaattat ttatagaggc gacagattta gctgataaga
     6481 aagagttggt tgaagacaat ctggtattag ttttagacaa agacgctatt aacctcgaag
     6541 aaagtattgt ggataatatc ttacttgcta ttccgctaca ggtcttgaca gaggaagaaa
     6601 agaaatcaaa agagttgcca gcaggtcaaa attgggcagt tttgacagaa gaagactacc
     6661 agtgtctaaa agaagaaaag caaaaagaaa ataatccttt tgctagcttg caagggttgt
     6721 ttgatgaata aaactgaata ttaaagatgt ctgtaatttt tatttgaaaa aacagctatt
     6781 ctttgatata ctctttagag aatatggtta cttatctaaa gtagaaggta ttttgaccat
     6841 agagggcaaa gaaggtaatg actattagat gcttcatatt ttattcgcta gaagactatt
     6901 tgaccattag aactgaaata gtctaggata tgagatgaat ttcatagttt tctttctggg
     6961 agaaaaagat agattaagag gataagggtt ggtataaatg acaaagaaaa ttttaattat
     7021 tgaagatgaa aagaatctgg ctagattcgt ttctcttgag ctgcaacatg agggttacga
     7081 agtcattgtt gaggtcaatg gtcgtgaagg gttagaaact gctttggaaa aagagtttga
     7141 tttaatcctg cttgacttaa tgttaccaga gatggatggt tttgaagtga cccgtcgttt
     7201 gcaaaccgaa aaaacaacgt atatcatgat gatgactgcg cgtgattcta ttatggatgt
     7261 ggttgcaggt ttagaccgcg gtgcagacga ctatattgtt aaaccgtttg ccattgaaga
     7321 actacttgcc cgtattcgtg ctattttccg ccgtcaagat attgaatctg agaagaaagt
     7381 gcctagtcaa ggcatttatc gagatctagt tttaaatcca caaaaccgtt cagttaatcg
     7441 tggcgacgat gagatttctc tcactaaacg tgaatatgat ttgcttaata ttttgatgac
     7501 taatatgaat cgtgtcatga cacgtgaaga attattgtca aatgtttgga aatatgatga
     7561 agccgttgag actaatgttg tagatgtcta tattcgttat ctccgcggca aaattgacat
     7621 tccaggcaag gaatcttata tccaaacagt gcgtggcatg ggatacgtta ttcgtgagaa
     7681 ataagtcata tggaaaatca gaaacaaaaa cagaagaaat ataaaaattc gttaccaaaa
     7741 cgactatcta atatcttttt tgttcttttt ttctgcattt tctctgcatt ttctctgcct
     7801 ttacactgat tgcctatagt tcaacaaact atttcttatt gaagaaagaa aagcagtcag
     7861 tctttcaagc tgtaaatatt gttagagttc gtctttctga ggtggactct aattttacat
     7921 tagagaactt agcagaagtt ttgtacaaaa acgataaaac acatctgaga attgatgaca
     7981 gaaagggcag tcgagtcatt aggagtgagc gcgatatcac aaatactcta gatgcgaatc
     8041 aagatattta tgtctataac attgataagc agatgatttt taccacagat aacgaagaat
     8101 catctcctgg cttgcatggt cctatcggtc gggtgtatca cgaccatatc gaagatcagt
     8161 atcgtgggtt ttccatgaca caaaaggtat attctaatcg gactggaaaa tttgtggggt
     8221 atgttcaagt ctttcatgat ttaggcaatt attatgtcat tagagcaaga ctgctgtttt
     8281 ggctactagt tgttgagtta tttggcacaa gcttagccta tttaatcatc ttaattacta
     8341 cgcggcgctt tttgaagcct ttacacaatt tacatggagt aatgcgtaat atctctgaaa
     8401 atcctaataa tttaaacctg cgctcagata tttcgtcagg agatgaaatc gaagaattgt
     8461 ctgttatctt tgacaatatg ttagacaaat tggagacaca tactaagttg caatcacgtt
     8521 ttattagtga tgtcagccat gaattacgaa caccggttgc gattattaaa gggcatattg
     8581 gtctcttaca acgttggggt aaagatgaca gtgatattct tgaagaaagt ttgacagcaa
     8641 cagcgcatga ggctgaccgt atggcaatca tgattaatga tatgttagac atgattcgcg
     8701 tacaaggctc atttgaggga catcaaaatg atatgacagt tttggaagat tctattgaaa
     8761 ctgttgttgg taattttaga gttttaagag aagattttat ctttacatgg cagtcagaaa
     8821 atccaaaaac gatagcccgt atttataaaa atcattttga gcaggctttg atgattctta
     8881 ttgataatgc tgtgaagtat tcccgtaaag aaaagaaaat cgcgattaac ctttcagtga
     8941 ctggcaaaca agaagctatt gttagagttc aagataaagg cgaaggaatt tctaaagaag
     9001 atattgaaca tatctttgaa cgcttttata gaacggataa atcacgtaat cgaacaagta
     9061 ctcaggctgg attagggatt ggcttgtcta ttctcaagca aattgtagat gggtatcatt
     9121 tacagatgaa ggttgaaagt gaattaaatg aaggttcagt gtttatctta catattcctt
     9181 tggcccagtc taaagagagt tagagtagct taaggcattg ttaatgtgac aggtatagta
     9241 tgtaatcatt agataatagt agcagtcttt tgccacaact ggttagaagc tgatgctatt
     9301 tttttagcaa tgatggatga catgaaagaa atactgtcaa tcgcgatgcc ttttgttatc
     9361 cttgataata tggtaaaata gtgtattaga ttaatttgat agaattgggg tgtttgcgtg
     9421 cgttgtccaa aatgtaatta ccataaatcg agtgttgttg acagtagaca agctgaagac
     9481 ggcaacacca ttcgtcgtcg aagagaatgt gaacagtgtc atactcgctt tactaccttt
     9541 gagcgtgttg aagaactccc tttattagtc atcaaaaaag atggcacacg agagcaattt
     9601 tctagagata aaatattaaa tggggttgtc caaagtgcgc aaaaacgacc tgtctcgagc
     9661 acagatattg aaaatgtcat ttctcgtatt gaacaagaag ttcgaacaac ctacgaaaat
     9721 gaagtgtcaa gtactgctat tggtaattta gtgatggatg agttggccga acttgatgaa
     9781 atcacatatg tacgctttgc tagtgtctac aagagcttca aggacgttga tgaaatcgaa
     9841 gaacttttgc aacaaattac gaatcgcgta cgcggaaaga aaaaacgttt aaataatgat
     9901 gaaaccaatt gatactttta catatctaaa acgcaacaaa gtaactcttg attcggtgac
     9961 tttaatacag ttgtactttc caattattgg aagtgacgca gtctctatct atcaatactt
    10021 tattcacttt tttgacgatg gtttacaacg tcataaattc agcgatattt taaatcacct
    10081 acagtttggt atgaaacgtt ttgaagatgc tcttgccata ttgacagcaa tggaattagt
    10141 gagtgtgtat cagctatcag atacatatct cattacgttg caccagccgc ttagccgtga
    10201 cttgtttttt caacatccag cttattctcg attattagaa caaaagattg gagaggtagc
    10261 tgtctctgag ttgcaggtaa ctgtcccaag tcaagcaaga aatatttcta agcgattttc
    10321 ggatattttt ggggtgcaag gagatttgac gaacgtacct caaaagccac aaaagaattt
    10381 tgacctttca agtttccagc aattaatggt tcgtgatggg ttacaatttg aagataatca
    10441 aaaagatatc atcagccttt acagtattgc tgaacagtat gatatgacgt ggtttgatac
    10501 ttatcaaata gctaaggcga cggctgttaa tgggaaaatt cgacctgaac gcttattggc
    10561 taaaaaaaat caaagcatga caaaaccaag caaagaaaat ttttcacagg ctgagcaaat
    10621 tattttgcga gaagcaaagc aagacagtgc tttagtcttt ttggaaaaaa ttaaaaaggc
    10681 tagacgtgca acgattacta aggatgaacg cattttattg caaacattgg ccaaaatgaa
    10741 ttttcttgat gatgttatca atgtcatggt gctttatacc tttaataaga caaaatctgc
    10801 taatttacag aagagttatg tcttaaaaat ggccaatgat tttgcctacc aaaaggtgtc
    10861 aacggctgaa gaagctatag tggttttgcg agccttcacg gatcgtcaaa gtcgtcggca
    10921 atcaaaagta aaaacaagtc aaagcaatgt gcctaagtgg agcaatcctg attaccaaga
    10981 gacaacaagt caagaagagc aggcgaaact agatcagttc aaacaggctg ctttgaagag
    11041 gttagaaaac ctaggaaaag ggggtgacta gatggaaaag attggagaaa ccatggcgaa
    11101 attgggtcaa aacactcgtg ttaatagcga ccagttgatt caaaccattt tagcggatcc
    11161 tgaagtagca agcttcatca gtcaacatca cttatctcaa gagcaaatta accttagctt
    11221 atctaagttc aatcaatttt tggtggaacg ccagaagtat caactcaaag atccctctta
    11281 tattgctaag ggctatcagc ctattctagc tatgaatgag ggctacgctg atgtgtctta
    11341 tttggaaacc aaagaattgg tagaagctca aaaacaggca gctatctctg aacggattca
    11401 actggtcagt ttgccaaaat cctatcgcca tattcattta ccagatattg atgttaataa
    11461 tgcgagccgt atggaagctt tctctgctat tttagatttt gtggaacaat acccatcagc
    11521 agagcaaaaa ggcttatatt tgtacggaga tatgggaatt ggcaagtctt acttgttggc
    11581 tgctatggcc catgaattgt ctgagaaaaa aggtgtgtca acgacccttc tacattttcc
    11641 gagctttgcc attgatgtaa aaaatgccat ttcaaacggc tctgttaaag aagaaatcga
    11701 tgcggtcaaa aatgtaccag tgctcatttt agatgatatt ggtgcagagc aagccacttc
    11761 ttgggtccgt gatgaggtgt tgcaggtgat tttacaatac cgtatgttag aggaattgcc
    11821 aaccttcttt acctctaatt acagctttgc ggatttggag cgaaaatggg caaccatcaa
    11881 aggaagtgac gaaacttggc aggccaaacg tgtcatggaa cgcgtgcgtt atttggctag
    11941 agagtttcat ttagaagggg ctaaccgccg ttaagtttga gatagcaatc aagaagaata
    12001 gctacacgta tgagtgagtg aaagaaaagg agaatcatgg ttttacctac cgttgccatt
    12061 gtgggccgtc caaatgtggg caagtccacc ttatttaatc gaatcgcagg agagcgcatt
    12121 tcaattgtag aagacgttga aggggttact cgtgaccgta tttatgctac tggggagtgg
    12181 cttaaccgcc aattctcatt gattgataca ggtggtattg atgacgttga tgccccgttt
    12241 atggagcaaa tcaagcacca ggctcaaatt gctatggaag aagcggacgt tattgtcttt
    12301 gtcgtttctg gtaaagaagg ggtgaccgac gctgacgaat atgtgtctaa aattctgtat
    12361 cgaaccaata ccccagtcat tttagctgtt aataaggttg ataatcctga aatgcgtaat
    12421 gacatttatg atttttattc acttggttta ggggatccct atccagtttc ttctgttcat
    12481 ggtatcggaa caggggatgt cttggatgag atcgttgaaa acttgccagt agaagaggct
    12541 gaagaaaatg atgatattat tcgcttcagt ttaatcggtc gtcctaatgt tgggaaatct
    12601 agcttgatta acgctatttt aggtgaggac cgtgttatcg ctagccctgt cgcagggaca
    12661 acacgtgacg ctattgacac gcattttacg gatgctgacg gtcaagaatt taccatgatt
    12721 gacacggctg gaatgcgcaa atctggcaag atttacgaaa atacagagaa atattctgtc
    12781 atgcgtgcca tgcgtgccat tgaccgctcc gatgtggtct tgatggttat caatgctgaa
    12841 gaaggtatcc gtgaatacga caagcgtatc gctggctttg cacacgaagc tggtaaagga
    12901 atgattatcg tggttaacaa atgggatacc attgacaagg ataatcatac cgttgctaag
    12961 tgggaagccg atattcgtga ccaattccaa tttttgacat acgctccgat tatttttgtg
    13021 tcagctttga cgaagcagcg cctcaacaaa ttgcctgact tgattaaacg tatcagtgag
    13081 agtcagaata aacgtatccc atctgctgtc ctcaatgatg ttatcatgga tgctattgct
    13141 attaatccaa cgccaacgga taagggtaaa cgtttgaaaa ttttctatgc cactcaagtg
    13201 tcagtaaagc caccaacatt tgtcgtcttt gttaacgaag aagaattgat gcacttctct
    13261 tatctacgct tcttggaaaa ccagattcgc gcagccttta cctttgaagg gacaccgatt
    13321 catctgattg ctcgcaaacg gaaataagaa atgaacatca actaaaatgc tgacctaaga
    13381 aataatctca tcattgataa ggactgtgtt gtgtatgtta caggagacag tcctttttat
    13441 aataccttta agggtgtaga cggaagatta gtagcaaaca aagaaaaagg attttgacaa
    13501 gaaatatcag tcggtttttg ctataatgaa aggataagca aaaaggtgga aaaatgatgg
    13561 ctagattaat tccaggacga gtaaggaatg aaggtattaa gctttatgag caaggtttag
    13621 tctcattcca agatgataat aaaggcattc ttcaaataga agtggagact tatcaggttc
    13681 aatatggagc agatgatgag gatatcactt gtcaatgcga cacatttcat atgaaacatt
    13741 attgcaagca tattgcagca gtcgagtatt ttttaaaaaa tgatcaaaaa ggtaagcttt
    13801 ttttaaaaca gttaacaaat caaacaaaaa tcaaagaaac aacaaagaaa atgacatctt
    13861 ttggtagtct ctttttagat agcttagcca tgaatgaaga tgattctgtt aaatacaggc
    13921 tgtctgctct tggtagtcga agcccttttt cgtcagatta ctggtggagt ctgaaaatca
    13981 atcgtttacc agatgatcgt tcttatgtga ttcgagatat taaaggcttt ttgcagctta
    14041 ttaaaaaaga aggcttttat cagattggaa aaaattattt tgaacaactt tcatggctgc
    14101 agtttgaccc atccagtcaa gaccttattg agtttttatg gcgcttagca tctaatactg
    14161 acaaagggga caacgagaac atttttccaa atcatgcaag gcatttgcgc ttacctagtg
    14221 gtttttttga agaaggtatt cactatttga cgtcacttta tgactttact tttgaggggc
    14281 cttctcaaac ttatcatcat ctttttgtcc gttctttgga agcagaggca ggcctttatg
    14341 agtttaaagt ggaagtgcat cgcaaatcta ttgaattgca aattgctgaa aaaaatgtgc
    14401 aatacctctt tgataatgac tatcttcttt atcaagatac cttttatcac ttgacgttaa
    14461 agcaacgaaa aatggttcag gctattcgta gtctgcccat tgaggccgac ttggctaaac
    14521 atattcattt tgatttggat gatcatgcga aattagctgc aagcttatca gattttaaac
    14581 agatcggtct agtagaggct cctaaaagct ttgctattag agactttgag gtgacttttc
    14641 aatttgattt gttaaatcga gatgaaatca gttgtcagct tatgtttgat tatggcaatt
    14701 accaagttag tgacaaagca agtttagaag cacttccttt tgctagtcat ttaaaaaaag
    14761 aagaaaaaat caatcgttct ttacttgctt ttggcttctc gccacaattt tactcaaaaa
    14821 agcgactaac aagtgcaaaa gagctctata ctttttttga agaaacagtt ccatgttttg
    14881 agcgcttagg taatgttgcg ttgagtacag ctatccaagc attacaagtg aaagaaatgc
    14941 ccaagatcgc tattagacgc aatcagggat tactagatat ttcgtttgat ttttcaacca
    15001 ttattgaaaa tgatattgac caagctgtta cagctctttt tcaaaataat ccttattttg
    15061 tgagtcaaac aggtcaatta gtggtttttg atgatgaaac tcaaaaagtt agcaaaagtt
    15121 tacaagaatt aagagcaaga cagctaaaaa atggtcactt gcaactggat ggcattagag
    15181 ctctacaagt atccaaactt tttgaaggca tgacatctgt tcatttttca aaggaattag
    15241 aagagttagc ctatcatttg cagcatcctg aaactttttc aataaaaccg ttaccagtta
    15301 aggctcaaat gcgagattat caacgcaacg gtgttcagtg gttatcaatg ctcaatcatt
    15361 atggctttgg tggcatttta gcagatgaca tgggacttgg aaaaactctc cagacacttg
    15421 cttttttagc tagtcacctg aaatcagata gtaaagtgct cattttatct ccatctagtc
    15481 ttatctataa ttggtttgat gaatgtcaaa aattcacacc tcagctagat gttgtagttt
    15541 cttacggact taaacaaatc agagatcaaa tcatcgaaga aggtcatcaa ataaccataa
    15601 ccagctattc ctcctttaga caggattttg agacctatca agcgtttcac tacgattatc
    15661 ttatcttaga tgaagctcaa gtgataaaaa atgcgcaaac taagatttca cactgtttac
    15721 gtgcgtttaa tacagccaat tgttttgcgc tttcgggcac tcctattgaa aataaaatgc
    15781 ttgaaatttg gtccattttc caaattgttt tgccagggtt gctaccgact aaaaaagagt
    15841 ttttaaaatt aacagctgag caagtatcgc gctatatcaa accctttgtg atgcgtcgta
    15901 aaaaagaaga tgtcctacca gaattacctg atttaattga aactaattat tcaaacgaga
    15961 tgacagatga acaaaaagct atttacttag cgcagttaag gcagatgaaa gatcaaattc
    16021 gaaattctag tgatgtggat attagccgtc aaaaaattga gattttatct ggtatcactc
    16081 gattgaggca aatctgtgac actccaagtc tctttatgga ttaccaaggc aaaagtggta
    16141 agctagatag tttgcgaatc ttattgacac aaattaaaga aaatggtcat cgggctttga
    16201 ttttttctca atttagaggg atgctggact tggccaagca agagatgact gctctaggat
    16261 tgacctctta tcaaatgacc ggatctaccc ctgccaatga acgtcaagaa atgactagag
    16321 cctttaataa cggttccaag gatgcttttt tgatttccct caaggcaggt ggagttggaa
    16381 tcaaccttac gggagcagac acagtgattt taatcgattt atggtggaat cctgctgttg
    16441 aaatgcaggc aatcagtcgc gcctaccgta ttggtcaaaa agaaaacgtt gaagtatatc
    16501 gcttaatcac tcgagggacg attgaagaaa agattttaga gcttcaagaa agtaagcgca
    16561 atttggtgac tacagttttg gatggcaatg aaaaccgagc aagtatgtcc attgaagaaa
    16621 taaaagaaat tttggggcta aacactcatt aatcttcctt gattttagtg acattaaaaa
    16681 ccctttaaag aagatgacac caaaagcacc ttatataacc tcgttaaaac gcttcttttt
    16741 gaaatatctt tattgatata gcgattgtca tttgctagta atgattaaaa catttagaaa
    16801 aagacaagtc atagaatcat caaggaatgc tttgaaaaat aacagtattt aagttataat
    16861 agaggatgct acaagaaggg agaatcaaaa aaggatggta aaaaatcagt ttcctttagt
    16921 tgcagatggc attgctatta gtgatccagc aaagcaaatg gctctgtatg aaaatgaaga
    16981 tctcattacc aacatccgtg gctattacca ggacaaggag tatgatgata ttgctagaaa
    17041 tgaggagttt actgctaaag caacttctcg gcaggcccct tctagtaagc gcttttgtag
    17101 caatgatgaa aaacaccatt atgtcaaaga ggcgcgtcaa aaagcaaagc aagatctcaa
    17161 ggaaaaaaga caggcttatc ttgccaaaga aatggcctat gttcctaaac aggtttctaa
    17221 aaagcaacag cctgcggatt cttctccttc tcaaaagcaa gcaacaacag aaatgagtcg
    17281 ttttacaaaa aagcttcatc aagacaacta tattttagct gagttgccaa aagaatataa
    17341 agagccaaaa aatcttcctc aacaaggaac tacaaaaaaa aataattacg attttttaaa
    17401 atccagtcaa atttacaata ataaagaaat gagacaacaa cgagaaaaaa caattgcgca
    17461 agagcttaat cttagtaggt ttgaggatct tccttaataa atctactcag cgtatgcaga
    17521 tgacaaagga gttaagatgt caaaaacgta tcattttatc ggaattaaag ggtcaggaat
    17581 gagtgccttg gcccttatgt tgcatcaaat ggggcataag gtgcaaggta gtgatgttga
    17641 aaaatactat ttcactcaaa gaggattgga acaagcgggc atcactatct taccttttag
    17701 cgaggacaac attacgccag atatggaact tatcgttggg aatgcctttc gtgaaaacaa
    17761 caaagaagtg gcctatgctt tgagacacca gattcctttc aaacgttatc atgacttttt
    17821 aggtgatttt atgaaatcat ttatcagttt tgcagtagca ggtgctcatg gtaaaacttc
    17881 tacaacgggt ttattgtcac atgtcttgaa aaatatcaca gacacatctt atttaattgg
    17941 tgatggtact gggcgtggat ctgctaatgc acagtatttt gtttttgaat cagacgaata
    18001 cgaacgccat tttatgcctt atcacccaga atactctatc attactaata ttgattttga
    18061 ccatcctgat tatttcacag gaattgctga tgtgcgaaac gctttcaacg attatgctaa
    18121 gcaggtcaag aaagctttgt ttgtttatgg tgaagatgac gaactaaaaa agatcgaagc
    18181 acctgcacct atttactatt atggttttga agagggcaat gattttatcg cttacgacat
    18241 tacgcgtact acgaacggat cggactttaa ggtaaaacac caaggagagg tcattggtca
    18301 gtttcacgta cctgcttatg gaaaacataa cattttaaac gctacagcag taattgcaaa
    18361 cttgtttgta gccggcattg atacggctct agtggcagac catcttaaaa ctttttcagg
    18421 tgtgaaacgt cgttttacag agaaaattat caatgacact attattattg atgactttgc
    18481 tcatcatcca accgaaattg tggcaacaat tgatgcggct agacaaaaat acccaagtaa
    18541 agaaattgta gcaatatttc agccacatac ttttactcgc actattgcct tattagagga
    18601 ttttgcttgt gctttaaatg aagctgacag tgtttattta gcccagattt atggttctgc
    18661 acgtgaagta gataaaggtg aagttaaggt tgaagatttg gctgctaaga ttatcaaacc
    18721 atcacaagta gtaacggtgg aaaatgtctc tcctcttctt gatcacgata atgctgttta
    18781 tgtttttatg ggagctggag atattcagct atatgaacat tcttttgagg aattacttgc
    18841 aaatttaact aaaaataacc aataacatgt cctgccttag gcaggttttc tcattctaaa
    18901 ggagtttgat atgttgatta gacaggttca aggatccgat ttggaagtta ttgctaccat
    18961 tgaaagtgac aatttttcac cacaagaagc aacgacaaga gcagttcttg aagagcgcat
    19021 acggctgata ccagatactt ttttagtggc acttatcgat caggaaattg ttggctatat
    19081 cgaaggtcca gttgtcacta ctcctatttt ggaggattct ttgttccacg gggtgactaa
    19141 aaatcctaaa actggaggct atattgctat tactagtttg tccatagcta aacattttca
    19201 gcaacaaggg gttgggacag ctttgttggc ggcactaaaa gatttagtag tagcgcagca
    19261 aagaacaggt cttattttga cttgtcatga ttacttgatt tcctattatg aaatgaatgg
    19321 gtttattaac caaggaattt cagagtctca acatggtgga accctttggt accaaatgat
    19381 ttggaaactt tagaatcaca gctgattcaa ctgttggttt gttaaaaata agtaacaaat
    19441 gcatcattta attgcaatta ggatactttt aagttataat ggcggttgat tatatttagg
    19501 aggattggct ttgaccgatt ttaaggataa agaccaacaa gatcagcagc gaagctttaa
    19561 agagcagatt cttgctgagt tggaaaaagc aaatcaaatc agaaaagaaa aagaggaaga
    19621 actttttcaa aaagagttgg aagctaaaga agcagctagg agaacggccc agctatatgc
    19681 tgaatataaa agacaagatg cttttcaaaa agagtctata gcacataaca ataagacagc
    19741 taaacacttt caagctataa aaggtgcggt aatgacttca gaagcgctta aaccgacttt
    19801 actttctgaa aaagaaaact catctttaaa aacgacaaat aagagagtcg tgcaggcaaa
    19861 tgagcttcaa gagactgcct ctaaagaatc tcaagtaccg ttaactattg agaaaggtca
    19921 ttcagtgaga cgaaaattaa gcaaacgcca acagactgag cgagctgcta aaaagatttc
    19981 aaccgttttg attagttcta ttattataac ccttttggct gttactctag caggagcagg
    20041 ctatgtttat agtgctttaa atcctgttga taaaaatagt gatgcctttg ttcaagttga
    20101 gataccatct gggtcaggca ataaattgat tggtcaaatt cttcaaaaaa aaggtttaat
    20161 caagaatagc actgttttta gtttttatac aaaatttaaa aactttacaa attttcagag
    20221 cgggtattac aatctgcaaa aaagtatgag tctagaagaa attgctagtg ctttacaaga
    20281 aggtggtaca gcagaaccta ccaagccatc tcttgggaag atcttgattc cagaaggata
    20341 cacgattaaa caaatagcta aagctgttga gcataatagc aagggaaaga ccaaaaaagc
    20401 taaaacacct tttaacgaga aggatttttt ggatttagtc acagatgagg cttttattca
    20461 agatatggta aaaagatatc caaaattatt agcaactatc ccaactaaag aaaaagctat
    20521 ttaccgtttg gaaggttacc ttttcccagc aacctataac tattacaaag aaactaccat
    20581 gagagaactt gtagaggaca tgctggcagc tatggatgct actttggtac cctattatga
    20641 taaaattgct gctagtggta agacagtcaa cgaggtattg accttggcct ctttggttga
    20701 aaaagaaggt tcaacagacg atgacagacg tcaaattgca agtgtctttt ataaccgcct
    20761 taatagcgga atggcactac aatctaatat agctattttg tatgcgatgg ggaaacttgg
    20821 tgagaaaaca accttggctg aggatgctac tattgacacc accattaatt ctccttataa
    20881 tatttatacc aatacaggtc tgatgcctgg tccagttgct agctcggggg tttctgcaat
    20941 tgaagcaacc ctaaatccag cctcaacgga ttatttatac tttgtggcca atgtccatac
    21001 tggtgaagtt tactatgcaa aaacatttga agaacactct gcaaatgttg aaaaatatgt
    21061 gaatagtcaa attcagtaaa cacaaacatg gtgcttaagc accatgtttg tgtttctgat
    21121 tcgttcaaaa aagaaaagag agaaaacaat tatggcagaa aaaacgtatc cgatgaccct
    21181 aacggaaaaa gaacaacttg aaaaagaact tgaagaatta aaacttgtgc gtcgtccaga
    21241 aatagtggag cgtattaaaa ttgcacgttc gtatggagat ctttcagaga actctgaata
    21301 cgatgccgca aaagatgagc aagcttttgt tgaaggtcaa atttcaacgc ttgaaactaa
    21361 gattcgctat gctgaaatca ttgacagtga tgctgttgca aaagatgaag tcgctatcgg
    21421 aaaaacagtt atcgttcaag aagttggaac aacagataaa gatacctatc atattgtagg
    21481 tgctgctgga gcagatatct tctcaggaaa aatttcaaat gaaagcccga ttgctcaagc
    21541 tttgattggt aaaaaaacag gtgacaaggt tagaattgaa tcaccagcag ctacttatga
    21601 tgttgaaatc atcagcgttg aaaagacaaa ttaatcagat gaagccatta tttgcctaac
    21661 cactaagtgt tttggttgct aatggctttt ctagtatctt caaatgaggt tgactgttag
    21721 gaaggtcaag tattaatcgc attgattatg agccaagagg actatagatc aaagatcgtt
    21781 ttcgatggtt atttaatgcc aaaagaaaag accagcacct taatgtactg accccaaaaa
    21841 gttggacact atattttaag gaagtgtatg atctaaggaa actgacacta atgattgacc
    21901 gttttgcaag actttattaa tgatttcttg ctttatttta aatgaataag tctgatacgt
    21961 ttccttcctt aacactatcg actccatact gacccatcag tcaaacggta tatctcaaac
    22021 gactacggtt tactccaaat tgattggcta gttgaggcca agaaacacct gatttttttt
    22081 aatgctaaat ttctagctta tcttcatagc ttaatttcat acaaaaacac cccaatcgtt
    22141 agattttttt gatatgtccc ctttcactag atgagtccag taaaaggggg catatcgttt
    22201 tttgtctaac ttttggggtg cagttcataa ttgtgctagg ttttttgtct ttcttaacgc
    22261 tttcgctgtt ttccagcatt acgattggat tttatttttt taggcaagtt agcctgttcc
    22321 atgttttgtg aaggcgtaac gtccttacga gaagaagttg attggtatgc tttaggcggg
    22381 tttttagcgt attcttcttt aatttgctta tgcaatcgag gttttaagag gtaggttgtg
    22441 attaactgtt gaataatact aaagaaacca ccaactagcc agtaaagacc aacaccagca
    22501 gggagtgaga aggacatgaa gatcatcatg ataggcatgg tgtacatcat cgtcttcatt
    22561 tgctcacgtt gttcttctga aacggccatc attgataacc atgattggaa gaagtaaaga
    22621 gcagcgataa ttgctgttaa cactaaacta cggctaccaa gatcaatacc cataaaggtg
    22681 cttgttgata ctcctttagt gtattgagcg gcaaaataca tggcagaaaa gaatggcatc
    22741 tggatgagaa gaggtagaca tccaatacct ccaagaggat taatcccatg agcacgctga
    22801 gcagccatta attctgtttg ggcagccatt ttttcttcct gactacttgc ctgtttgata
    22861 cgtttgttga ttggttcaaa aacaggtttc aagaaggcca ttttctcaga ttgataactt
    22921 gctttccaag attgatatag acctagtggt aagataagtg ttctaacaat aatggttacg
    22981 atgatgatag ccagtccata acctagtcca gcattgtttg caaagtaatc gataaagtat
    23041 gacatgggtt ttccaagaaa ttcccaaatc atacctttgg gatttccgtg agcgtctctt
    23101 cccacacagc ctgtcaaggt gaatagaatt gacagtgcta gtcctgaaaa gaggatgcga
    23161 tttaatgtta gtttcaatgt gtttatcctt taattttaat atacttatct attttacagt
    23221 ttttttcaga aattcacaat agttctgaag gccgattttt acttgcctat ttgaaagtcc
    23281 tgaaagtctt caaaattagc catggtgaca tccacataag tgacttttgc ccatttggat
    23341 ggtcctttac gaacttcttg aataaatgtg gctattttat ctgaatcttt tgattgggcc
    23401 aggatttcaa cggtcccatc gttgttattc cagacacgac cataaatatc tcctatatct
    23461 agagctaaag tatgggtagc gtatcgaaaa ccaacacctt gtacacgtcc agaaacaatt
    23521 aaacgtactt tttgcataag aagggcctcc ttgcttttat tatagcacat acttagcagg
    23581 aaatctcttt agctaattgt ctacttcctg tcacttttac taaagacaag aatacaaaaa
    23641 tgagatagtt agtagtacta acagtaaaag aggtttgtct attttaaaaa tagtatcaaa
    23701 aaaaggtctt ttaggtttaa aacattgaac tgcccccaaa ttgaccatct aagaagttga
    23761 tgctttcaaa tgctgtcgcg tatggtataa taggtgcatg gttattacat caaaaacaaa
    23821 tcaactaatt aagcaaacaa aaaaattatt gcaaaaaaag catcgaaaac agtcctattt
    23881 gattgagggc tggcaccttt ttgaagaagc ccaaaaatca ggacaagttt ttcgccacat
    23941 ctttgtttta gaggaaatgg tggagcgtct agcaggtgag caagaactcg ttattgttag
    24001 cccacaagtg ctcaaggagt tgaccgactc tcctagtcca caaggcattg ttgctgaggt
    24061 ggagatacct aagttagcct ttccatcaga ttacaaaggg aaatatttgg ttttagagga
    24121 cgtccaagac ccaggaaatc ttgggaccat cattcgtaca gcagacgctg cacggtttga
    24181 tggggtcttt ctttctgaaa aatcagcaga tatttacaac caaaaaaccc tacgttccat
    24241 gcaaggtagc cattttcatt taccaatttg gcgaacagat gtctatcagc tttgtcgaga
    24301 gctccaagag tataaaactc ccatcctagc aacaactctg tcaaagaaat ctgttgacta
    24361 taaaagcctc acacatcatg aaaggttggc tttggtgttg ggaaatgaag gccagggcat
    24421 tagtgctgaa atggcagccc tagcagacca actggttcat attacaatgc ctggtcaggc
    24481 ggaaagtttg aatgttgccg tagcagcagg aatcctcatt ttcagcttga tttaagctaa
    24541 tatgatataa taaccaagtg gggtgattat gttatgcatt atacagaaga taaagaatat
    24601 atggaacacg tcggtcattt gatcgctcat cctcgctttc aaaaattgag tcatattgtt
    24661 cagcaccaac attcaacgcg tcttgaacat tctatcaatg tttcttattc cagttataaa
    24721 ttagccaagc gatttggttg ggatgctaaa agtacagcca gagggggctt acttcatgat
    24781 ttcttttatt atgattggcg cgtgaccaag tttaataagg gtcatgcctg ggttcatcct
    24841 cgtattgctg tacgaaatgc gaaaaagtta acagaactca ataaaaaaga agaggatatc
    24901 attctaaaac acatgtgggg agcgaccatt gcttttccgc gttacaagga aagttatatt
    24961 gtgacaatgg tagataaata ctgggctgtc aaggaagcag tgacaccttt aagacaaaaa
    25021 tggtctaatc gacggtttct tcgccgcaag accctccaaa gtcataatcg ttaagtaaag
    25081 gagttattat gaacgatcac gttatttata cacaatcaga tgtgggatta aatcagtttt
    25141 ttgctaaaat ttatagtcta gtgggaatgg gagtgggttt atctgctttt gtttcttatt
    25201 tgatgcttta tccatttaga gaaaatttaa tctctattct tgttaatcag ccgatgattt
    25261 actatggtgc tgcgattatt gaacttattt tagtttttgt agccagtggt gcagcacgaa
    25321 aaaacacacc agctgcattg cccatttttc ttatctattc tgcgctaaat ggctttaccc
    25381 taagctttat tattgtggca tacgctcaaa cgacagtttt tcaagcattt ctttcttcag
    25441 cagctgtgtt ttttgccatg tcaatcattg gtgtcaagac taaacgggat atgtcaggtc
    25501 ttagaaaggc tatgtttgct gctttgattg gtgttgttgt ggctagtctg attaatcttt
    25561 ttattggtag tgggatgatg agttatgtca ttagtgtgat ttccgtgcta attttctcag
    25621 gtctcatcgc atcagataat caaatgatta agcgcgttta tcaagcaaca aatggccagg
    25681 ttggtgatgg ctgggctgtt gctatggcct taagcttgta tttagatttt attaacttat
    25741 ttatcagcct tcttcgtatt tttggaagaa atgattaaca ttaaaaagtg agtataacta
    25801 ctcacttttt aatgttaaca ggataagtaa actgtaagga agaaattcga gatagatata
    25861 agatgaggct gctaaaagac ctagtgttaa tttgtaaact ctttcttttt ttggtatact
    25921 attaaggatt aaatacgagg agaatataga tagatatgtc aacagctatt tggattttat
    25981 tacttattgt tgcccttggg gtaggtgttt ttggtgggat ttttattgcc cgtaaacaaa
    26041 ttgaaaaaga aattggtgaa cacccacgtt taacaccaga agctatccgt gaaatgatga
    26101 gccagatggg gcaaaaacca agtgaagcaa aaatccaaca aacttatcgt aatatcatca
    26161 aacaatcaaa agcagccgta tccaaaggta aaaaataaaa gctaattgtt ataggggaaa
    26221 cctttgtgat agttagaagt gaacagtctt tgatctcaat gttcagtagc acttgtctta
    26281 tcagttagat ttgtcaactg ttcagggttt aaaaagaaac tcagttggct atttccaact
    26341 gagtttttca tatcgtcagt aaggaagtaa acataatgga tacaagacca attgggtttt
    26401 tagattctgg tgtgggaggt ctgaccgtcg tttgtgaatt gattcgtcag ctccctcatg
    26461 agaagattgt atatattggt gattcagcaa gagcccccta tggtcctaga cccaaaaaac
    26521 aaattaagga gtatacttgg gagctagtca attttttgct gactcaaaat gttaaaatga
    26581 ttgtttttgc atgcaatacc gcaacagcgg tggcttggga agaagtaaaa gcagctttag
    26641 atattcctgt tttaggggtt gtcttaccgg gggcaagcgc agctattaaa tcaacgacaa
    26701 aaggccaggt tggggtcatc ggaaccccaa tgacagtggc ttcagacatt tatcgcaaaa
    26761 aaatccagct attagcacca tctgttcaag taaggagtct tgcttgcccg aagtttgtac
    26821 cgattgtgga atcaaatgag atgtgttcga gtatagctaa aaaaatagtt tatgacagtc
    26881 tatcaccatt agtcggtaaa atagataccc ttgtactagg atgtactcac tatcccttgt
    26941 tacgaccaat tatccaaaat gttatggggc catctgttaa gctgattgac agtggagcag
    27001 aatgcgtccg agatatctct gtcttattaa actattttga cattaacggt aattatcatc
    27061 aaaaagctgt caaacaccgc ttttttacaa cagcaaatcc tgagattttt caagaaattg
    27121 cctcgatttg gctgaaacaa aaaataaatg tggagcatgt caccttatga gtgaaaaaat
    27181 ttacgaatac aaagatgaaa ataactggtt tatcggaaag atgactggtc ataatttaat
    27241 atcgggctgg ggagtcaaac acacgacaat caaaaaaata gatgaccttt tagacggtat
    27301 tgccgcaacg ttagattggg aaaatcctaa aggttacgat gtttcggtgg tgcgttatca
    27361 gtctccttta tctctcatca cctttattat cgacatgata aatcaagaga cccagcgtaa
    27421 gattaaggta actccccatg caggcacgat tttattaatg gaaaatgcga aactgcttgc
    27481 agtttatctc ccagaaggtg gagtttcaac ggctacattt tttgcgacta gtgaacaggg
    27541 atttggggat attattttaa tcgctacacg aaacgaggga aaaaccaaag agttccgcaa
    27601 tctgtttggc cagctaggtt atcgtgtgga aaatctcaat gattatccag aattgccaga
    27661 agtagcagaa actggtacta cttttgaaga aaatgctcgc ttgaaagcag aaacgatttc
    27721 acgcctcaca ggaaaaatgg tattagcaga cgattcagga ctaaaagttg atgccttggg
    27781 tggtttacct ggggtttggt cagctcgttt ctcaggacca gatgccacag atgccaagaa
    27841 taatgccaaa ctcttacacg aattagctat ggtgtttgac caaaagaagc gctcagctca
    27901 atttcatacg actttggtag tggctgctcc caataaagat agtttggttg tggaagccga
    27961 gtggccaggc tatattgcta cgcagcctaa gggagaaaat ggttttgggt atgaccctgt
    28021 ctttatcgtc ggagagactg ggcgtcatgc tgcagaatta gaggctgacc aaaagaatca
    28081 gttgtcgcat agaggtcaag cagttcgaaa attaatggag gtctttccag catggcaagc
    28141 aaaacaatca tagtaatgag tgactctcat ggtgaccgag atatcgttca agccattaaa
    28201 gacaagtatc ttggtcaagt tgatgctatt ttccataatg gggattctga attaaacagc
    28261 tcagatccta tttgggctgg tatttatgtc gttggcggta attgtgacta tgatacaggt
    28321 taccctgatc gtttagtaac tcaattaggc acagttacga ttgcccagac acatggtcac
    28381 ttgtaccata ttaatttcac ttgggataaa ctggactact ttgctcaaga agtagcagca
    28441 gatatttgtc tatatggaca cctacaccgt ccagctgctt ggcaagttgg gcaaaccctc
    28501 tttatgaatc ccggatcagt aacacaacct cgcggagaaa ttaacgagaa attatatgct
    28561 cgtgttgaac taactgatac tcaaattaaa gttgattact ttacaagaga tcataaactt
    28621 tacccatcac tgtctaagga atttaaacga tgatcgcaaa agaatttgaa acgtttttaa
    28681 tgagtcattt agataattat cttatcccgg aacaagactt ggctattttt atcgacacac
    28741 ataatgcaga ccatgtgatg ttacttttgg tgagcaatgg tttttctaga gttcctgtta
    28801 tcacacggga gaaaaaatat gtgggaacca ttagcatctc agatattatg atgtaccaat
    28861 ctaaaaggca gctgacagat tgggaaatga gtcaaacaga tattggcgag atggttaata
    28921 ccaaaattga aaccattagc attacttcca gcctaacaga aattatgcac aagttaattg
    28981 atttcccatt cttaccggtt gtagatagag cgaatcgctt tgttgggatt attacgcgaa
    29041 aatctatatt aaaggctgtc aacagtcttt tacatgattt tacagatgat tacacgatta
    29101 taaaaaaatg aagagttata ttgaaccttt tattgctagc aaggctttat ctcaaaatag
    29161 tcaaaaagct tatcgatacg atttgcaaca gttttgtcaa ctgattggtg aacgtgtcaa
    29221 tcaagacaaa ctattacttt atcaaaatag tatagctaac ctcagtttat ctgcaaaaaa
    29281 acgcaaatta tcaacagcta atcaattctt atactacttg tatcaaataa agtatttaaa
    29341 tagctatttt cgattaacag acaccatgaa agtgatgcgg actgagaagc agcaagctgc
    29401 tattattaat actgatattt tctatcaaaa aacccctttt gtgtgggggc aattaatcag
    29461 cttattaata ttggagctgg gtttaactcc gagtgaagta gctggtattg aagtagctaa
    29521 cttggattta aattttcaaa tgttgacgct aaagactaaa aaaggtgtgc gtgtattacc
    29581 tttgtcgcaa atactaatcc cttttttaga acaacaactc gttggcaaag aagcctatct
    29641 ttttgaacat cgaggcatcc ctttttcaag acaatggttt tttaatcacc taaaaacctt
    29701 tgttcgaagt attggttatg aaggattaac tgctcaaaaa ttacgagagc aatttatttt
    29761 gaaagaaaaa ctagctggta aatcgataat agaacttagc gatattcttg ggctgaaaag
    29821 ccctgtgacc ttagaaaaat actacaaatc ataatggata taaaacttaa agattttgaa
    29881 ggtcctcttg atttactctt gcacttggta tcacagtaca aagttgacat ctacgaggtt
    29941 cctattgttg aggttattga gcagtacctt aattatattg aaaccttaca ggtaatgaaa
    30001 cttgaagtgg ctggtgacta catgctgatg gcaagtcagc tcatgttaat caaaagtaga
    30061 aggctattac caaaggtggt agaacacatc gaagaagaag atttagaaca agatctgtta
    30121 gaaaagatcg aagaatatag tcgctttaaa gcagttagtc aagcgttagc gaagcaacat
    30181 gaccaaaggg caaaatggta ttcaaaacct aaacaagaat taatttttga agatgctatc
    30241 ttacaagaag ataaaacggt gatggatcta tttctagctt tttcaaacat aatggcagct
    30301 aaaagagcag ttttaaaaac caaccataca gtcatcgagc gtgatgatta taagattgaa
    30361 gacatgatgg cttctatcaa acagcgactg gaaaaagaaa acgttattag cttatcagcg
    30421 atttttgagg aatgccaaac attaaatgaa gttatcagta tatttttagc tagtctagaa
    30481 ttgattaagc ttcacgtggt atttgtagag cagctctcta attttggggc tatcatacta
    30541 cgaaaggaga agaaatgacg tatttgtcac agatagaagc gctgctattt gttgcaggtg
    30601 aagaagggtt aagtttgcga catctagcgt ctatgttatc attaacgcca acagctcttc
    30661 aacagcaatt agaaaaactc tctcaaaagt atgaaaaaga tcaacattct agtctttgtt
    30721 tgatagaaac agctaatacc tacaggctag taactaaaga aggttttgca gaactcttgc
    30781 gtgcttatgc caaaacacca atgaaccaaa gtctatctcg tgcgagttta gaggtcttgt
    30841 ctattgttgc atacaaacaa cctattacac gaatagaaat tgatgacatt cgaggggtaa
    30901 actccagtgg agctttgagt aaattattgg catttgatct cattagagaa gctggcaaaa
    30961 aagatgtggt tgggcgtcct catttgtatg cgacaacaga ttattttctg gactatatgg
    31021 gaattaatca tttagacgaa ttgattgaag tatctgccgt tgaaccagca gatgaagaga
    31081 ttgctctttt taggacacaa gactgagttt tgcttgtcat caaatagcaa atggcgttta
    31141 caaaaggatt tgttttaagg cgttttagtt gaaaaaaagc cttaaactag ggacaacaaa
    31201 aagttgctca aaagaaagaa gaatataatg cgaattaaca aatacattgc ccatgcgggt
    31261 attgccagtc gacgtaaggc tgaagaattg attaagcaag gcttagtaac cttaaatggt
    31321 caggttatta cggatttagc aaccactgta aaatcgggag acgtggttga aatagaagga
    31381 agtcctattt acaacgagga aaaggtttac tatttgctta ataaacctcg tggcgctatc
    31441 tcaagtgtgt cagatgacaa aggccgtaaa acggtactgg atttactgcc tcaggttaaa
    31501 gaacgcatat accctgttgg acgattggat tgggacacat caggggtcct tattttaacg
    31561 aatgatggtg attttacaga tactatgatt catcctagaa atgaaataga caaggtttat
    31621 ctggcgcgtg tcaaaggaat tgcaacgaaa gaaaatcttc gtcccttaac tcgaggaatt
    31681 gttattgatg gtaaaaagac caaaccagct cgctacaata ttgttcgtgt agaagctgat
    31741 aagaatcgat cgatcgtaga attgactatc catgaagggc gaaaccatca ggttaaaaaa
    31801 atgtttgagt ctgtggggct tttggttgat aaattatctc gtacacgttt tgggaccgtc
    31861 gacttaaagg gactaagacc aggagaagca agacgcttaa ataaaaaaga aataagtcaa
    31921 ctgcataact tagctaatac gaaaaaatga tgaaaaaact attaatagta tctgttaaag
    31981 cttatcaaaa atacatttct cctttatcgc ctcctagttg tcgctacaag ccaacctgtt
    32041 cagcttatat gttaactgct attgaaaaac atggtactaa gggaatacta atggggatag
    32101 caagaatatt aagatgtcac ccttttgttg ctggtggtgt cgatcctgtt ccagaagatt
    32161 ttagcctaat gagaaataaa aacacgtcta aaaacgctga aaaggcatga ctttatcaaa
    32221 aaatggcttg acattgatag ctgaagtgtt ataatggaaa acaagcattc gttggtttaa
    32281 atcaaacctg ttatgattta agttagcgag tcaccatcaa ccacattgtt tgctgagcat
    32341 gactccgagc agtgtggttt tttaaattaa aaagagtaaa tgagattatg acgacaaaag
    32401 aacttatcaa caaaaacgac aaagtaaaaa aggctcgcaa tcatattgtc ctgtttcaac
    32461 cccaaattcc acaaaatact ggtaatattg ctagaacatg tgctgcaact aatgcacctt
    32521 tacacattat taaacccatg ggatttccta ttgatgaccg caaaatgaag cgtgccggct
    32581 tggattactg ggacaagtta gaactgcatt tttatgatca tttagaacag tttatcaatc
    32641 aatgtcacgg acagcttcac ctgattagca agtttgcagt taataattat tctcaagcta
    32701 cttatgctga tggcgattcc cattatttct tgtttggacg agaagataca ggcctgccag
    32761 aagattttat gcgagaacat gctgaaaaag cacttcgtat tccgatgaat gatgagcatg
    32821 tacggagttt aaatgtctca aatacggttt gtatggtgat ttatgaagcc cttagacaac
    32881 agggctttca agggttagag ttaaagcata cttacgaaca cgataaacta aaataatgga
    32941 ctttttaaaa gcgtcagttt ttggcaacat gcgttgtcag tagctgacgc ttttaaaaat
    33001 ttagtcaaag ctattgctat ctaggtttaa atctgctatg ctagaagtgt cttcagggca
    33061 gggtgtgatt cccgaccggc ggtgactagg taactagaag tccgcgagcg caagctgatg
    33121 tggtgtaact ccacaaccga cagtatagtc tggatgagag aagaccgggc tttttgtgta
    33181 ggcttatttt agctacacaa taacgacgga acttctttca atttgaaaaa attggaggaa
    33241 ttttttaatg tcaaaaacac ataaaatgat tatgattggt atactttctg cgatatcatt
    33301 tctattgatg ctagttagct ttgccattat tccaggcgca gcttttttaa aaattgaatt
    33361 tagtattatt cctgtcttat ttggtttaat gattatggac ttaaagagtg cttacttgat
    33421 tttgttattg aggtccttat tgaaactctt tttgaacaat cgtggggtta atgattttat
    33481 tggtctccca atgaatatta tcgctatcgc tttatttgtg acggcttttg ccttagtttg
    33541 gaaccgtcaa aaaacgctta gtcaatatgt atttgctagc ttactaggca cagggttatt
    33601 aacgtttggc atggttgttc tcaattatac ttttgccatt cctttatatg ctatatttgc
    33661 aaatattgat atcagagctt atattggtgt tactaagtat atgatgacta tggttattcc
    33721 gtttaatctt gttgaggggt tgatatttgc aattaccttt tattttgtgt atattgcaag
    33781 taaaccaatt ttagaaagat acttacacta atatgatgac aaacaaacaa actcactttt
    33841 taatagcttc ttttgcattg ctaatctttg ttataatagg ctatacggtc aaattttttc
    33901 ctgaacgttt ggcacttcta gataatacta ttcaagcaga gattagaggc aaccttccta
    33961 tagtgctgac gcaattcttt aggggtgtta ctgtatttgg aaatgtcatg acacaagttt
    34021 tgttagttat tgtgtcggtc ctagttttat tctttatgaa gtggaaaatt gaagccttgt
    34081 ttatcttgtc aaatggtgcc attgcagcat ttttgattac gactctcaag ctcttttacc
    34141 aaagaccaag acctgctatt gagcatttgg tttatgctgg tggctattcg tttcccagtg
    34201 gccatgcgat gggtagcatg ctgatttttg gtagcctatt gattatttgt tatcagaggc
    34261 tacattcaaa actattacaa tttgtgacta gcatgatctt tataatacta attttattaa
    34321 ttgggttatc tcgtatttat ctaggagtac actacccaag tgatatttta gcaggctttg
    34381 tattaggatt tggtattttg cactttattt atccttttta taagcaaaaa cgatttgaat
    34441 ggcgatttct tttgaaacaa gactaatttt tcttgagaag acataggctt atttaaatca
    34501 tttagaataa cattggcaag catcaccccc ttgattgcca gtgttatttt agttttagtt
    34561 agatgatgtg agctgatgat tagtaaatat gtttagataa aaaacgatta aagtgctatg
    34621 taacgtcaga aaagacgtga tttttgttga tctgtaatca ttaagtaagc tgatgtagaa
    34681 gtagtgaatt ctaatgactg agctatcttt tgcatagatg actatcttgc tagtaatgat
    34741 ttgtgctaca atagaaacat gaaaaaaaga tatcagacat taaatgagca ttaccgtcaa
    34801 ctatttggcg caaaaatgtt taaagttccg attgatgccg gctttgattg tcccaatcgt
    34861 gatggaacgg tagctcatgg aggatgtact ttttgcacag tatcaggttc tggagatgct
    34921 attgtagcac cagatgctcc aattaaagag caattttata aagaaattga ttttatgcac
    34981 cgtaaatggc ctgatgtcaa tcgctatttg gtttattttc aaaactttac caatactcat
    35041 gatacagttg atgtgattcg cgaccgttac gaacaagcta ttaacgaacc tggagttgtt
    35101 ggtattaata ttggcacacg gcctgactgt ctaccagatg ataccattgc ttacttagca
    35161 gaattatcag aacgcatgca tgtgacagtg gagctaggct tacagacaac ttatgaagaa
    35221 acttctaggc taattaacag agcacattct tatgatttgt ataaagaaac ggtgaggcga
    35281 ctaaggcatt accccaacat taatattgtc tcgcacttga ttaatggatt gccaaaagaa
    35341 actcatgaca tgatgcttga aaatgtgaga cgctgtgtaa cagacaatga cattcaagga
    35401 attaaattgc atttgctgca tttgatgacc aatactagaa tgcaaagaga ttatcatgaa
    35461 ggacgcttaa agttgttgag tcaaaaggac tatgtttcga ttatttgtga ccagctagag
    35521 attatcccta agcatattgt gattcaccgt attacaggag atgccccacg cgatatgttg
    35581 attgggccca tgtggagtct aaataagtgg gaagtattga atgccattga taaagaaatg
    35641 gaaagacgag gaagctttca gggctgtaaa gttgactaat ttgtctcatt ttgacggatt
    35701 tggataggag aaaagtgatg ctaaaacgcc ccattcatct ctcgcatgat tttttagcgg
    35761 aggttgtgga taagtctagt gtggttgttg atgccacgat gggtaatgga aatgatactg
    35821 cctttttggc acaattagct aaaaaggttt atgcttttga tgtgcaagaa caagctatta
    35881 gaaaaacaag tgagcggtta gcgcagctag gattatcgaa cgctgagctg attttagcgg
    35941 gtcatgaagc ggttgatcag tatgtgacag agccggtgcg cgcagcgatt tttaaccttg
    36001 gttatttgcc cagcgcagat aaatctatta ttaccttacc aaataccaca ctccaagctt
    36061 tatcaaaact actaacgtta ttaatggtag gtgggcgtat tgctattatg gtctattatg
    36121 ggcatgatgg aggcagtttg gaaaaagatg ctttattaga ttttgtcaag caattagacc
    36181 aaagaaaggt ttctgcaatg ctttatcagc ctcttaatca ggtgaatacc ccaccttttt
    36241 taatcatgtt ggagaaatta gcagacgttt agctcttatc cctgtgtcaa gtctactaga
    36301 agttctgcga ttatttcggt ggaaaaagaa gaaatcccat aggctttggc tataaatgtg
    36361 atataatgaa gtcactatat tattttttta ggagttacat taacatggaa gaccctgtga
    36421 gtcagccctt agtgattcaa tttttattgt tagttgtttt aaccttgtta aatgcttttt
    36481 tttcagccag tgaaatggcc ttagtttctc tcaatcgttc tcgggtggaa caaaaagcag
    36541 cagacggtga taaaaaatac gctcgtttgt tgcgggtttt agaggaacct aatcattttt
    36601 tatcaacgat tcaagttggg attaccttta ttagtttact atcaggagca agtttatcag
    36661 cttctttggg taaggtgatc tcaggttggc taggtaattc agcgaccgca aggacagctg
    36721 gtactatcat ctccttggtt ttcttgactt atgtctctat tgttttagga gaattgtatc
    36781 caaaacggat tgccatgaac ctcaaagaca agttggcgat tgtttcagcc cctattatca
    36841 ttggattagg gagactggtt agtccctttg tatggctctt atcagcttct actaatttac
    36901 tgagccgact tacccctatg acctttgatg atgcagatga gcaaatgaca cgtgatgaaa
    36961 tcgagtatat gttatcaaaa agtgaggcga cccttgatgc tgaagaaatt gagatgttgc
    37021 aaggagtttt ctcacttgat gaaatgatgg cgcgtgaagt catggtccca aggaccgatg
    37081 ctttcatgat tgacattaac gatgatccgc ttgaaaatat tcaggaaatc ttaaaacaaa
    37141 gtttttcacg cattcctgtt tatgatgtgg ataaagataa aattatcggt ctcatccaca
    37201 ctaagcgtct cttggagtca ggtttccgcc agggatttga tcagattaac atgcgaaaaa
    37261 tgttacaaga acctcttttt gttcccgaaa ccatttttgt agatgatctc ttacgccagc
    37321 tgcgcaatac ccaaaatcag atggctattt tgctagatga atatggtggt gtggcaggac
    37381 ttgtgacttt ggaagacttg cttgaagaaa tcgtcggtga aatcgatgat gaaaccgata
    37441 aagcagaaca atttgttcat gagattggag acaataccta tattgttgtt ggtactatga
    37501 ctttaaatga gtttaatgac tattttgata ccgaactaga atcagatgat gtagatacca
    37561 ttgctggttt ttatttgaca ggtatcggaa ccattccaag ccaggagcaa aaagaagcct
    37621 acgaaataga taacaaagac aaacatttag ttctaatcaa cgataaagtc aaagatggcc
    37681 gtattacgaa attaaaatta atcctgtcta atatagaaca gattattgag gaagactagg
    37741 ctccatgcct agtctttttg atgaaaagtg ttataatgaa aatgtaaaaa cgtttacaag
    37801 taatgaagga gatgcaatga ctgagaaaga ttatggacaa gtaacaggga tggtgcattc
    37861 gacagaaagt tttggttctg tagatggtcc aggcattcgt tttatcattt tcttgcaagg
    37921 ctgtaaatta cgttgccaat attgccataa tccggatact tgggagatgg aaaccaacaa
    37981 ttcaaaaatc agaacagtca atgatgtctt gaaagaagcc cttcagtaca aacatttctg
    38041 gggaaaaaaa ggaggaatta ccgtatctgg tggtgaagct atgcttcaaa ttgattttat
    38101 cactgcctta ttcatcgaag ctaaaaaatt aggtatccat accacactag acacctgtgg
    38161 ctttacctat agaccgacac ctgaatacca tcaggttctt gataacttat tggcagtgac
    38221 cgatttgatt ttattggact taaaagaaat tgatgaaaaa caacataaaa ttgtcacgcg
    38281 tcagcctaat aaaaacatat tgcaatttgc taggtattta tccgacaagc agattcctgt
    38341 ctggattcga catgtcttgg ttccaggctt gactgatatt gatgatcatt tgacacgatt
    38401 gggtgagttt gtcaaaacct tgaaaaatgt cgataaattt gaagttttgc cttaccatac
    38461 catgggagaa ttcaagtggc gtgagctagg tattccttat cagttagaag gtgttaaacc
    38521 accaactaag gaacgcgttc aaaatgctaa aaatctgatg cagaccgaat cttacacaga
    38581 atatatgaat cggattcatc agtcataaga gctgttatag ggttgaggtt tcctcaactt
    38641 tttaaagtat tataagcaga tcttttgtaa tcttcctttg attttagggg gtaattttgc
    38701 taaaataaaa tgaataaaca aaatgaggta gaatgattat gtcaaaaatt ttagtttttg
    38761 gtcatcaaaa tcctgatacg gatgctattg catcatctta tgcttttgat tacttatccc
    38821 aaaaagcgtt tggtttggat actgaagtcg tagctttagg aacacctaac gaagaaacag
    38881 cttttgccct tgattatttt ggtgttgagg caccacgtgt ggtagagtct gctaaagcac
    38941 aagggtctga acaagtgatt ttgacagacc acaatgaatt ccaacaatcc attgcagata
    39001 tccgtgaggt tgaggtatat ggtgtggttg atcaccaccg tgtggctaat tttgaaactg
    39061 caaatccttt atacatgcgt gtggaaccag taggatcagc ctcatctatt gtttaccgta
    39121 tgtttaaaga aaatggcatc gaggtgccaa aagcgattgc agggatgctc ttgtctggtt
    39181 tgatttcaga taccttgttg ctgaaatctc caacaactca tgtgtctgat caccttgtcg
    39241 ctgaagaatt ggcagagcta gcagaagtga acttggaaga ctatggaatg gctcttttaa
    39301 aagcaggtac aaaccttgca agcaaatcag aagtagaatt gattggtatt gatgccaaaa
    39361 catttgaatt aaatggcaat gctgtgcgcg tggcacaagt gaacactgtt gacattgcag
    39421 aagtcttaga acgtcaagaa gctattgaag cagccattaa agatgccatg gctgcagaag
    39481 gttattcaga ttttgttttg atgatcacgg atattgttaa ctcaaactct gaaattctag
    39541 ctattggagc aaacatggac aaggttgaag cagcctttaa cttcaccctt gacaacaatc
    39601 atgccttctt agcaggtgcc gtttctcgta aaaaacaagt ggttccacaa ttgacagaaa
    39661 gttttggagc ttaatgaaaa gacgctttaa aaggacttga tttttttgac caagtccttt
    39721 tgtcactctt ctatgttata atagaaggta tgataacagt atttcattca gataaactca
    39781 ccagacaacc tttctttcaa gaccttatca attatctcga ccagcatgat cacgttatat
    39841 tacgagagat caaaaaagcc tttcctaatg tgacaggtat tgacaaggcc atcgaaagct
    39901 atgttcaagc tggctatatt cgccgtgaaa ataagcgtta tggaatcaat cttcctttgg
    39961 tgagttctga tcagcagctg gccttagaca ctatgctttt tgtggacacc tgttcagcta
    40021 tgtatgaaaa tattttagcg gttgtttttg agactcagct aacaaaccaa accaatcacg
    40081 tgatgatcaa ggaaaagacc aacatcacga gagacgattt gaccctggct aattattttt
    40141 accgtctcaa aagaggtgag aagccatcag ctgagcagct ggacttgtat gacctcttgg
    40201 gggatgtgaa tcaggaatat gcccttaaat atatgacaac ttttttgctt aaattcatgc
    40261 gcaaagacct tgtgatgcaa aaacgtcctg atatatttgt ggaagctctg gttacacttg
    40321 gttacctaaa acaagtggag cctacaacat accagctgct aatgaccttg gataaagaaa
    40381 gtttaacctt tatagcacca tagaaaaaag ctaggaacaa ggactgttct tagctttttg
    40441 agtgctttta ttttgttttt gccattaagt aaagaaaata aggggctccg ataagcgaca
    40501 ctaaaatccc tgtctggata ttagtgccaa ccagatacac tcgcccgact gtatctgcaa
    40561 caagaagtag gatcattccg attaaaatac taatgggtat tgttatttta tgattactcc
    40621 ctaccaagta tgtactaaag tgtccagcta ttaagccgat aaaactaata ttaccaacca
    40681 aaagaacact caaagcacct aagccagctg ctaagacaag tatcaaacga cgcttacggt
    40741 ttaaagggag tcctagccca atagcagtat tatcagctaa tcccataata ttaaggaaat
    40801 gggcttgact ataagtcaat agccaaaaac acaataataa aggagcgatg acactcagag
    40861 taggccagtc gtctcctatt aattggccgc taagccaatt gatgaccaaa tcgactttgt
    40921 agcgattaat atgaccaaca agagcaacca ttagacttga aagcatggta gtaacagcta
    40981 caccagtaag aattaaccgt gtaggatcaa tttgtccttg ttttgtcaaa gatagccaat
    41041 aaacgctaaa ggttgttaca acagcaccaa gcatggcaaa taaaggcaag taatggctga
    41101 tatgagcttg ctcaaagaaa gaaaaggaga ccacaatagc caaagagata cctgctccta
    41161 tagtaatacc taatacacca gagtcagcta agggatttcg tgttaaacgt tgtaataata
    41221 gccctgataa agcaagagaa ccgcctccta gacaagcagc tagaattctt ggcagacgaa
    41281 tgttaataac gatgaaagat atggcatggc tagattttcc caaaaacaca tggataaggt
    41341 ccaaaaaaga tagatgagat tctccaaggg acaaagctaa tcccataaga cttacaagta
    41401 gcaggatcag gctagtatat aaccccaaaa ggtgtcggtg agatttcaat agcggcctcc
    41461 tcttcttatt aaccataaaa agcatggaaa accaattaag ctaaccaatg ccccaagagg
    41521 ggtttcataa ggcggattga gattacgaca agcaatatca acccatacca tgaaactagc
    41581 gccagaaact gcacaaagcg gcaaaaggta tcggtaatga tgaggtgtaa agtgtttcat
    41641 aagatgagga atgactaagc cgataaaaga aatgcttcca gcaatggcta cagctgctga
    41701 tgataaaata agaaccaaaa tcataaagac tgcactgatc aagttggtct tttgcccaag
    41761 agcttttgcc tgagactcac ttagactaag gacggtcagg tgataagata atagctgggc
    41821 taaacaaaga ctaagaataa taagaggagc aatatagccg atcatttgcc aattgacccc
    41881 gacaagacct cctgcttgcc agccgataac agcatttgcc agatgatagt aattggtaat
    41941 accttgacct aatgctgata gcagtatgga aaccatagct cctgctaaga caaggcggag
    42001 ctgatggtag cctttgccag attgataaga aaggccaaag actaaggttg ctgccaggct
    42061 agaccctaac aacgaaagca gaataatgag ggaatagtgc aagtgaggta caaacgcata
    42121 agccagtacc aaggctagtc ctgctccagc attaatgcct aaaaggccag gctcagcgat
    42181 aggattacgt gtgattgctt gcatgatagt tccagaaaca gctaacgcag agccagttaa
    42241 ggtagcacca aaaagtctcg gtaatcgtat agcgagtaaa acattggctt tatggccgtt
    42301 ttgctttcca aataaaatag agttaagatc ctgatgtgat aaagcaacgg ctccaaagcg
    42361 cagatgacag taaatagcaa cacataagct aaaactaagt agcacaaaga caagccaaaa
    42421 gatatgtgac ttagtgatta tctgcgtttt tttaagcaaa aacgctcgag acacaaaaag
    42481 ggatgcttag ttttcacttg ataagattgc ctctcgtaaa gtctctaatt gatattctaa
    42541 agaaagagga tcagtaaagt aaaaaacatt ggcattgact ttgatcacat ggtgtttttt
    42601 cacagctgga atggattgcc atagcttact ttcatataga gcagaaccag tcttatcatc
    42661 ttctgcagca acgacgacat aatcaccaat atagtctggc aagacttcct gcgacaatga
    42721 caggtaacct tgtttaaaaa cttcagtctt cactttttca ggagcatcat aatggaaagc
    42781 ttgatggata acctctccgc cacgtcccca gtctttacca aaaaggtaaa cgtctttttc
    42841 ataaagcccc ataatagtaa aggttgcttt gtcacctgta acggctttga cttctttttc
    42901 ataagctgct gttttagttt tccaatcttt taaccatttc ttggctttgc cttctttgtt
    42961 aaagatgcgg ccgaagtcag ataacacttg taaataatca cgtttgcggt attcaatcga
    43021 aataacaggc gcaatttctg ccaattgttt aatattttct tctgtagagc caacaacaat
    43081 gaggtcaggc ttaagcgttg taatggcttc taaatcagtt gcagcaactt gctttgcttt
    43141 ttttacagtc tttgctaaga tggggttttt cttgtcataa gaagtaaccc cgactagatt
    43201 catatctaat tttttgaggt aaccagtgta agttgaagcc agactgacta ctcgcttagg
    43261 ctgtttagga atatctccgt aataagtcac accagcaatt tgaggcatag gcgataaact
    43321 ttttgaggcg gtgttagaat gattagttgc ttgattacca caggcgatta aggtaatagt
    43381 tgtcaaacag agtgttaata gtagagttaa ttttttcatg tatgctaatt ctcctagaat
    43441 aaagttattg aagctgataa gtcagcacta taggacagtt gtggatagga tcatcaacca
    43501 gtaccggttt gatttggaag atgtcttgaa tgataggtga agtcataaca tctgctatag
    43561 taccagtata atggatcttg ccatgtttca tagcaatcag atgatccgaa tagcgggctg
    43621 aaagattgag gtcgtgaaga accataacaa tagtcttgcc ggcatcctta tttagggatt
    43681 taacgagctc taggatttct agttgatgat ttaaatctaa ataagtagtt ggctcatcta
    43741 aaaaaatagt atcagtgcct tgggctaatg ccattgcaag ccaaaccctt tgacgttgcc
    43801 ccccagaaag agcatcaaca ggttgatcag cataggccat gacattggtg gcttgcatag
    43861 cccaatgaat ggcttttttg tcagctggac taagatttcc aaagtaagat tgatggggaa
    43921 aacgtccgta agaaaccaat tcgtaaacag ttatgccgtt agttgcttct tgaacttgag
    43981 gtaaaagagc tagtttttta gcaacctctt tagtttctaa tgtggcaatg ttttgcccat
    44041 ttaaatatac aactccctgt tttggtggta ataatcttgt cagtgctttt aataaactag
    44101 acttcccaca gccattggcg ccaataatgg tcgtaatttt accttcagga atataaaacg
    44161 ataatttatc gatgatggta cgctgttcat aggcaattgt gaggtcttca gcactaattg
    44221 ttgtcatatg gttgtctcct ttctaaaaag agtcaaaggg ttgatgaaag tgcacattaa
    44281 agtattcatc tgcccatttt aaaatagttg agaagtagct tattttctca aaatcttcac
    44341 tattatagca tagaaaaaag gcttaacaaa gccttttttg atgtgatttt taggatgtat
    44401 taaaaaagaa atattagttt agaatgatta aaaacaatag cgataatcat tctaaactaa
    44461 cgtcaacata ctctagaggt agtgtctggc gattgctaaa tcaccagcat aagctacttg
    44521 ttgtccttta acaatttgat aagcatctgc gcctttccca gcgataatca cagcatcttt
    44581 tgctccttgg caaagagaca tggctttttg aatagcttgc tcacggtcac taataatctc
    44641 tactgggcgt gcgatatggc tggcaatttc ttttgaaata tcttctggat cctcgaaatt
    44701 agggtcatca gcagtgagaa tgacggtgag gtttggatgc tgatgaatca ccctaccaaa
    44761 atcagctcgt ctgctctcgc ctttatttcc tggtgcacct aaaatcaaca ttaatttgcc
    44821 tgtctgatgt tcttccacaa cgctgagtaa tttttctaag ctgtcaccat tatgggcata
    44881 atcaacaaaa actttagcat gatttgtcat agtgaggact tccatacggc ctgggacgcg
    44941 agtcttagcg ataccttttt gaatatcagc taggctagca cccaaacgaa ggcaggcaag
    45001 tccagctgcc atagcatttt cttggttaaa atggccaatt aattgaatgt cataatggcc
    45061 agctaattgt cctttagctt caaaggagaa ggcttggcta gtggtgatct ggttgtcaga
    45121 caagggacca taaaacacat gctcttgatc cgctacctga tccgctagaa atgaaaaatg
    45181 atccatcccg ctattgatca caacagctct gctattctcc attaaaagac gcttatgata
    45241 gaaataatct tcaaacgttg gatgctcgat tgggccaata tgatcaggac taatatttag
    45301 gaaaacccca acatcgaacg taagcccata gacacggtca acgaggtaag cctgactaga
    45361 aacttccata atcaagtggg tcatgccatt agtcacacac tcagccatca tagcaaaaag
    45421 atccaagctc tcaggagttg tgagttgtga tttgaaaaag gtcttgccat ctaaggtggt
    45481 attcatggta gaaaacatgg caggtttata ggattctttc aacatgtggt aggcaaaata
    45541 agcagccgtc gtctttccct tagtacctgt aaaagctagt agtttgagct tttcttgagg
    45601 gttgccatag aaaaccatgg caattagact catagctttt ttgatatcag tgaccaaaac
    45661 aacgggaata ccaagctcgt aatctacctc tgaaatatag agttgtaatc cgttagtgat
    45721 tgcttcttta aggtagtcag ctttgaaagt tgccccttta gcaaaaaaaa gggtcttgcc
    45781 atctacttga cggctatcgt aactcaagcg ctcaaaacta aagccttgat aatggtagtg
    45841 gtatccgtcg gcatcaagaa cctcacgaaa attatggtct ttttttaaaa tgtctaataa
    45901 ttgttcaatg gttatcatac ccttatttta tccttaaagt tcttgtttta caagtcacaa
    45961 gcaaaagttt ataataaagc taatagaaac taggaaagaa tagatatgtc gacagaaaaa
    46021 aaacaactga cacaagaaga attgatggtt cagggagcag cctggtccac agctggcaat
    46081 ttcattagcc gacttttggg agtgttatac attattccct ggtatatttg gatggggcaa
    46141 tacgcgattc aagccaacgc tcttttcaat atggggtata atgtttatgc ttatttttta
    46201 ttgatttcaa ccacaggact caatgttgcg attgctaagc aggttgccaa gtacaattcc
    46261 atgggacaaa ctgagcatag ctatcaatta atccgaagta ccctaaaact catgcttggt
    46321 ctgggcctta ttttttcagc cattatgtat ctgggctctc ctttatttgc gagcttatct
    46381 ggtggtgatg acacacttgt tcccattatg cacagccttt ctttagcagt ttttattttt
    46441 cctgtaatga gtgtcattcg aggtatcttt caaggccaca ataatatcaa gccttatgcg
    46501 attagtcaga ttgctgagca actcattcgg gttatctgga tgcttttgac caccttcctt
    46561 atcatgaaat taggttctgg tgattacgct tcagcagtaa ctcagtcaac ttttgcagcc
    46621 tttatcggga tggtggctag tatgggtgtt ctggggtact atctttggaa acagggactt
    46681 ctagcagcta tttttagtaa gccagatcat actgtttcca ttgatatcaa gggcttgttg
    46741 cttgaaacct taaaagaatc catccccttt atcgtaacag gaagtgccat tcaagccttt
    46801 caattgattg atcaatggac ttttgtcaat actatgactc tttttacaga ttatagccgt
    46861 tctcaattgc ttgttttatt tggttacttt aacgcaaacc cagccaaaat tacaatggtt
    46921 ttaattgcag tagcagcatc tattggtggt gtaggcattg ccttattaac tgaaaattat
    46981 gtcaaaaaag acatgaaagc agctgctcgc ttaatcatta acaacattga aatgttagta
    47041 atgtttttgt tacccgctct tactggggca attattttag caagacctct atattctgtt
    47101 ttttacggag ctagcgagga tcgtgccatt cacctctttg tggcggtcct cttccaaacc
    47161 ttgttgatgg cgctttacac ccttttttca ccgatgcttc aagctctttt tgaaaatcga
    47221 aaagcgattt actactttgc ctatggtatc ttgattaagt tagttttaca gataccgctt
    47281 atttatttgc tacatgctta tggtccttta ctagcgacga cgattgcttt agtggtgccg
    47341 atttatttga tgtatcgacg cctatatcag gttactcatt ttaaccgcaa actgttgcaa
    47401 aaacgtttat tattaacctt gattgaaacc ttattaatgg gactggtcgt gtttgtggcc
    47461 aactggctat tgggctatgt ctttaaaccg acaggccgct tgaccagcct tctttacctc
    47521 ctcattattg gtggcttggg aatgacggtt tacacggcac tcaccttgct gacgcatcaa
    47581 ctggataaat taattggtag caaagctagt cgccttcgtc agaaattagg ctggcattaa
    47641 tataatgaca ccaagaacga tttcgtgagt gcttatcgaa atcgtttttt tcttaatgat
    47701 ctcgcttagt aaaggtagcc gataaaaaat caggatttcc caagcaaact actgatattt
    47761 ttggtataat gataaaagtg taaaaaaata gaaggaagta tatcaacatg ggaaaatgtc
    47821 aagttatttc gcatccgctt atccaacaca aactttcaat cttacgtcgt caaaccacat
    47881 caactaaaga ttttcgtgag ttggttaatg aaattgcgat gctgatggga tatgaagtgt
    47941 cacgcgacct tcccttagaa gatgtcgaca tccaaacgcc agtatcaaaa acggtccaaa
    48001 aacagttagc tggtaaaaaa ttagctattg ttccgattct tcgtgctggt attgggatgg
    48061 ttgatggctt gttaagtttg gtaccagctg caaaagttgg ccatatcggc atgtaccgta
    48121 atgaagaaac tcttgaacct gttgaatacc tcgttaaact accagaagat attaaccaac
    48181 gacaaatttt ccttgttgat ccaatgttgg caacaggtgg ttcggctatc ttagcagtgg
    48241 attcgttgaa aaaacgtggt gcagcaaata ttaagtttgt ctgtttagtt gcagcaccag
    48301 aaggggtgaa aaaacttcaa gaagctcatc cagatattga tatcttcaca gcagcacttg
    48361 atgatcattt aaatgaacat ggctatatcg tgccaggatt gggagatgct ggtgatcgtt
    48421 tatttgggac aaaataaaag agacaaccat caaatagtag cctttttagg ccaatcgttc
    48481 ttgattttgt taaaaaaatc agagagattt ctcttcttta aaggaaaagc aagtttatga
    48541 tttgaccttt attgaccaaa atattataat aaagacaatc agtaaaaaag agatgaccta
    48601 gtgggttgcc gtctctcaaa atgacgctac taaaaaccct tgtagattgg agaatgtatt
    48661 atgattcctg ttgttattga acaaactagc cgtggagaac gttcttatga catttattca
    48721 cgtttattaa aagaccgtat tatcatgtta acagggcctg tcgaagacaa catggccaac
    48781 tctgtcatag cgcagctctt attccttgac gcgcaagaca acacgaaaga tatctaccta
    48841 tatgtcaaca caccaggtgg ctctgtctca gcaggcttgg ctattgtcga taccatgaac
    48901 tttatcaagg ccgatgtgca aactattgtc atgggtatgg cagcttctat ggggacagtc
    48961 attgcttcat caggaacaaa aggcaaacgc tttatgttac caaatgcaga gtatatgatc
    49021 caccagccaa tgggtggcac aggcggtggc acgcaacaaa cggatatggc tatcgcagca
    49081 gaacatctct taaaaacacg tcaccgttta gaaaaaatct tagcacaaaa tgctgggaaa
    49141 acgattaaac aaattcataa agatgctgag cgtgattatt ggatgagtgc tgaagaaacc
    49201 ttgacttacg gtttcattga tgaaatcatg gaaaacaacg aactaaaata aagaggatat
    49261 ctgcaaaagt attctagaaa tttctaggat gctttttctc ttagaaagga aaataatgat
    49321 acagcctact gcattaaaac agcttcaaga gttaaaacgt cagttcagat ccctttgcaa
    49381 ccaattatga gatagtttga ggatgatcct tagcagctgt gtgcaagaag ttatgacgat
    49441 ttcataaagg atgacctagc cagtctttct tcgtctcttt tacttaaagt gtggtataat
    49501 cagattatgc tagccaaaat taaaaaaggc attgccatta aaggtgttgt agatcggctt
    49561 atcctagatc tcataacaat gctgtagtac cgcccttacc ttgctactaa aggcgctgtt
    49621 gaagcacaaa ttgacttgca aaggatcttg actgataggt atatgtctgg tggaatcgcc
    49681 aaagcagcaa aaagaccaag acccttattt ggtctctacc aaaatataat agaaaaggat
    49741 ttagaatgtt tcaaaaacaa gaacgtattg gactcgtcgt ttacctgtat tataaccgag
    49801 atgccagaaa gttatcaaaa tttggtgatt tatattacca ttccaagcgc tctcgttatc
    49861 tcattgttta tattaataaa aatgatttag acacaaaatt agaagaaatg agacgtttga
    49921 aatgtgttaa agacattaga ccatcagctt ttgatgatat tgaccgccaa tttgtaggta
    49981 accttcatcg cgacgaaaca aacaaccatc aaaagggtta acaaccccct agttactgat
    50041 tagcgtttta gatttagtta gcttattaaa gtaagaaggt tttgacagat gctcacacta
    50101 cttcaagaca atgagacaac tagagcatta gtgaataact gagttgacgg tcacttcttt
    50161 aataagaacg gataggattg gtcctaaaat agagcactgc aaagatatgc cagtgctttt
    50221 tagctcattt tttgataaaa tagaactact aaaaagtgaa ggaaataaga tgatcacagg
    50281 aaaactcata accgttgaag gtccagatgg cgcagggaaa acgactgttt tagagcaact
    50341 cattccactg ttaaaacaaa aagtggctca ggagatcttg acaacaagag agcctggagg
    50401 tgttgccatt tcagaataca ttagagaact tattttagac atcaaccata ctactatgga
    50461 ccctaaaaca gaactcttac tttatattgc ggctcgaagg cagcatttgg tggaaaaggt
    50521 actaccagct cttgaagcag gccagttggt ttttattgat cgtttcatcg atagttcagt
    50581 agcttatcaa ggtgcaggac gcggtttgat caaagcagac attcagtggc tcaacgagtt
    50641 cgcaacagat ggtttagagc ctgacttgac cctttatttt gatgttcctt ctgaaattgg
    50701 tttagcacgg attaacgcga accaacaaag agaagtcaat cgtttagatt tggaaacaat
    50761 agagatacat caacgagtac gaaaaggata cctagcctta gctaaggagc atccaaaacg
    50821 tattgtcaca attgatgcga ctaaaccatt gaaagaagtt gtctctgtcg ctttggaaca
    50881 tgtcttagcc ttgcttttag cctaggataa gggaggggag gaatggattt agcgcaaaaa
    50941 gctcctaacg tttatcaagc ttttcagacg attttaaaga aagaccgtct gaatcatgct
    51001 tatctttttt cgggtgattt tgctaatgaa gaaatggctc tttttttagc taaggtcatc
    51061 ttttgtgagc agaaaaagga tcagacgccc tgcgggcatt gtcgctcttg tcaattgatt
    51121 gaacaaggag attttgccga tgtgacggta ttggaaccaa cagggcaagt gattaaaacg
    51181 gatgtggtca aagaaatgat ggccaacttt tctcagacag gatatgaaaa caaacgacaa
    51241 gtttttatta tcaaagattg tgacaaaatg catgtcaatg ccgctaatag cttgctaaag
    51301 tatattgagg agcctcaggg agaagcttac atatttttat tgaccaatga tgataacaaa
    51361 gtgcttccga ccattaaaag tcggacacag gtttttcagt ttcctaaaaa cgaagcctat
    51421 ctttaccaat tggcacaaga aaagggatta ttaaaccatc aggctaagct agtagccaaa
    51481 cttgccacaa ataccagtca tctagaacgt ctgttgcaaa cgagcaagct tttagaactg
    51541 ataactcaag cagagcgttt tgtatctatt tggctgaaag atcagttgca ggcatattta
    51601 gcgttgaacc gtctggtaca gttagcaact gaaaaagaag aacaagattt agttttgacc
    51661 cttttgacct tgctcttggc aagagagcgt gcgcaaacgc ctttgacaca attggaggct
    51721 gtctatcagg ctaggctcat gtggcagagc aatgttaatt ttcaaaacac attagaatat
    51781 atggtgatgt cagaataagt gcaattggaa ttcgttatgg ggaaacgaag cttgtcaaaa
    51841 gacttgcccg tactcccttt tcagcagaag agcacatgga tttttacaac tgttaaaaga
    51901 tttagcggcc gattttaggt caagaagtga gctgccccag attaacagcc aagaagattt
    51961 cattttctat ggaggctatg gaccgtgtgg caggccactg tgctgcattc gtttttggga
    52021 aaatttctga cagtatctat taaaatacta aaaaatcaag ggttatcatt gactttgggt
    52081 aaagcaacaa gcccttatgg ccgtttgctt tgctgtctct atgatgaagg tggcttttac
    52141 caataaagca agaaaaaatt ccctgaatat ggtaccatag tagagacaag tgatggccct
    52201 gcaacagtag cagccgttga tatatttaca gatcccatta aggtgcggtt aaaagaccag
    52261 ttgaccttag tcacttatgc tttagaggag gttaaagtag gtgaataaaa aagaattatt
    52321 cgatgctttt gatggatttt cccaaaattt aatggttact ttagctgaaa ttgaagccat
    52381 gaaaaaacaa gtccaatcac tagtagaaga aaacacgatt cttcgcctag aaaatacaaa
    52441 actacgggaa cgtttgagtc acctagaaca tgaaacggta gctaaaaatc cttccaaaca
    52501 aaggaaggat cacttagagg gaatttatga tgaagggttt catatctgca attttttcta
    52561 tggacaacgt cgtgaaaatg atgaagaatg tatgttttgc agagaattat tagatagaaa
    52621 gtaagggcat gcaggttcaa aaaagtttta aagacaaaaa aacaagcgga accttgtatt
    52681 tggttccaac cccaattggc aatctgcagg acatgacctt tagagcagtg gcaacgttaa
    52741 aagaggttga ttttatttgt gcagaagaca caagaaacac aggtcttttg ctaaaacact
    52801 ttgacattgc taccaagcaa atcagctttc atgagcacaa cgcctatgag aagattcctg
    52861 atttaattga tttattaata tcaggacggt cactagctca ggtgtctgat gcaggaatgc
    52921 catcgatttc tgatcctggg catgatttgg tcaaggctgc tattgatagt gatatcgcag
    52981 tcgttgcttt accaggtgcc tcagctggga ttacagcttt gattgctagt ggactggctc
    53041 ctcaacccca tgttttttat gggtttttac ccagaaaagc agggcaacaa aaggctttct
    53101 ttgaggacaa acaccattac ccagaaacac aaatgtttta tgaatcgccc tatcgcatca
    53161 aagataccct gaccaatatg ttggcttgtt atggtgatcg tcaagtggtg cttgtcagag
    53221 aattaaccaa gctttttgag gagtaccaac gggggtcgat ttcagaaatc ttgtcctacc
    53281 ttgaggaaac acccctcaaa ggggagtgtc tgctgattgt ggctggagcc caagtagaca
    53341 gtgaggttga gctgacagct gatgttgact tagtgtctct agtgcaaaaa gaaattcaag
    53401 caggagccaa gccaaatcag gctattaaaa caattgctaa agcttaccag gtaaatcgcc
    53461 aagagcttta ccaacaattt catgacttat aagtcatcgt aggttaggag aaaaacaaat
    53521 gacagaagat caagcaacta tccttatttt aggagtatac ggaatcatat tggctgtatt
    53581 cttattatca gctttattat gccttatcgc taactggcga ctctttaaaa gagcaggtta
    53641 caaaggatgg tatagtctca ttcctttcta tgcaggtttt gtcaaacaca aaatcacttt
    53701 tggagaagat aataaatggt tttactttat tggttgggtc attgctattt attattacta
    53761 tgtgcacttt tgctatgtcc gtgcttttgg tggatcaaag ggtctagcag tatttggctt
    53821 gtttttccca ggcattgctt ctttgatagt ggcttttgga aaaacttata ccacacaaga
    53881 atgccaccct gtgccacatc ttttaaacta agagaaaaaa gaccatcaat tggatttatt
    53941 gatggtcttt taggtgttta aatgatttta gtcccgtgaa caatggccgt tccagtgagt
    54001 tgactcaagc tttggcaatt ctcagcagtg acgcctcccc caatcatgat ttcaatgcgt
    54061 ttattggcat aggtcacaag acttttaagc tgttccacat tgtctgtaat aggagtagct
    54121 tcaggtgagc catgagttag cacacgcaca aagccataat caatcagttg gtcaagcgct
    54181 tggtgctggt gatcagtcgg aatccggtca aaagccatgt ggaaaaccag tggcaagcct
    54241 tgtgtagcag gcagtaattg ctcgatagcg tcggtatcca gttgattttc tgaggtcagc
    54301 aagcctaaga ctagcgcatc tgagccagct tcaacagctt ttaagatatc ttcttccata
    54361 gcttttagtt cgaggtcgtt atagacaaaa tcgccaccgc gaggtcgaat catggtcgct
    54421 acgctaatct ttttatcgtg taagagctga caggcttctt tgatgacgcc ataagatggc
    54481 gtggtccctc cgacagctag gttatcacag agttccacac gactgacttg accagcatca
    54541 agggttggca gtagtgtgag gttctcagca caaaattctt taatcatttt tagttctcct
    54601 ttatcactaa tattatagca cgaatgaagc tagtcatcag gaaacatttt tgtcaaatca
    54661 tggacattat gctatactca ctagtattaa aagtaggcca aaacagcagc aaatactttg
    54721 aaaaaagatt gctatgttct acggcaatat cagtctttac caacgaactc tcaagaagaa
    54781 aagaaagaca aagcttagca ttttaaaaaa gccccccttt ttttgtgaaa tgatgaccaa
    54841 aaacaggcgc ctcacgccta aaacagttac cctaaaggag aacaaatgat tacgatttac
    54901 caatacccaa aatgtagcac ctgccaaaga gccatggctg aattaaagca actggttagt
    54961 gactttgaag ccattgacat caaagctaat ccacccaaag ctcaggacct caaacattgg
    55021 atggaaacat ctggttatac catcaaaaat ttctttaata ccagtggtaa cagctaccgc
    55081 gaattgggac ttaaagataa aatagaccag cttagccttg ataaagctgc tgaactttta
    55141 gccacagatg gtatgttgat taaacggcct attctgatta aggacggtaa cgtcttacaa
    55201 gttggctatc gcaagccata tcaagagttg gatttaggat aatgcgacaa agtctcaaaa
    55261 aaggacaagg caacattata acgccttgtc cttttttggg atctgttttt agacattaga
    55321 gatcaatatc tagtaaaatt ggcgtatggt cttggcgttc cccagaagaa atcatttcag
    55381 aacgcttaac cttatccacg attcggtttg aagctagcca atagtcaatt ctccaaccgg
    55441 tattattgat tttgctggtt ttactacgtt gtgcccacca ggtataaaca tgaggaatat
    55501 cgccgtgcaa gtgacgaaaa gtatctgtaa agcctcttgc taataggtta gtaaagcctt
    55561 gacgttcttc gtcggtaaaa ccaggagaac gtcgattgct gcttggattt gccaaatcaa
    55621 tctctttatg ggcaacgttg taatctcccg tagccaaaac aggcttttga gcatccagtt
    55681 cagtcaaata atcagcgtat ttgtggtccc aaatttgacg gtcatctaac cgtcttagac
    55741 catcaccagc attaggcgta taaacctgtg tgacgaaaaa gtcttcaaat tctagggtaa
    55801 tgatacggcc ctcagcatcc attgttgttg gggcaccaat ttctggaaaa gtaatgacag
    55861 ggtttaacgt gtttttgtac aggaacatgg tgccagcata gcctttccta gcaggctcaa
    55921 ctgaagaacg ccacacatgc aaatagtttg gaaagtaact aagtagggtc tcaatatgtt
    55981 ttttggtagg ccccttagca gataatttag tttcttggat ggcaataata tccgcatctt
    56041 gagcgactaa agtgtctaaa acagcgcgtg ataaaagcgc acgaggggac tctcctgtga
    56101 gagcagcatt taaggaatca atgttccatg aaatcagttt catttggttt ctctttctaa
    56161 cagatagtct tgttgttatt gtaacaaaaa acgaaacgat aagcgacttt gggcacctag
    56221 cccccataaa acagtctagc caaatgaagc atagcagcgt aagaacaaga caaggaggtg
    56281 atcagtgagc atatcgtttg acagttaaga gtaggattac tataatagaa acataaatgt
    56341 aagcgctaac aaaataaaaa atataggaga atgtcaatgg cacaaaaaac agtcatcacc
    56401 gaagaaacaa ccgattttgt tatggatttc aaaacaagta gcgctgaggg aaatgttgat
    56461 tttattaacg tttttgacct tgagaaaatg gcacaacagg tcatccctaa aggagccttt
    56521 ggttatattg ctagtggtgc tggtgatacc tttaccctcc atgaaaatat tcgctcattt
    56581 aatcataaat taattgtccc tcactccctc aaaggggttg aaaatccgtc aacagagatt
    56641 acgtttgatg gtgatcactt aacctctcct cttattttag cacctgtagc ggctcataag
    56701 ctggccaatg aacaaggaga agtagcgtct gccaaaggat tgaaggaatt tggaagtatc
    56761 tacaccacta gttcctactc aacaactgac ctgccagaaa tcagtgctgc cttaggtggg
    56821 acaccccatt ggtttcaatt ttattgcagt aaagacgatg gcattaatcg taatattatg
    56881 gatcgtgtca aagcacaagg ttgcaaagct atcgttttga cagcagatgc aacagttgga
    56941 ggaaaccgcg aagttgatag gcgaaacggc tttgtttttc cggtcggtat gccaattgtt
    57001 caagaatatt tacctgatgg tgcaggtaaa acaatggatt atgtctataa atcagctaaa
    57061 caagcgctta cctcaaaaga tattgaatat atcgcaacct actcaggcct gcctgtttat
    57121 gtcaaaggac cacagtgtgc tgaggatacc ttgcgggcat tggacgcagg agcatcaggt
    57181 atctgggtaa ccaatcatgg tggccgtcaa ttagatggtg gtccagctgc ttttgattcc
    57241 ttacaagaag tcgctgaagc agttgatcac aaagttccta ttgtctttga ctcaggtata
    57301 agacggggtc aacatatttt caaagctctt gcttcaggtg ctgaccttgt tgccttgggg
    57361 cgtccagcga tttacggctt ggctatggga ggaagcattg gtactcgtca ggtctttgaa
    57421 aagttaaatg acgagttaaa aatggttatg caactggctg ggacacaaac tatccaagat
    57481 gttaaagcct ttaaccttcg ccacaatccg tatgattcat cgattccatt tgatcaaaat
    57541 gcactacgct tagattagaa cagacaaaaa cctctgctat catgtcacaa atagtagagg
    57601 ttttacactg caaaaagagg tatgaaaatc caataacata gttacaaggc tttcgtttaa
    57661 taccccccac taatagatta aaatgaaaga cttcttacat taatagaagt ttctgttgct
    57721 tttctcagaa aaatgtggtt aaataatcaa atattattaa cgaaaaatga gttaatgatt
    57781 aacattaaac tggttttagt taaaacattt aggagggtat caggtggaga aaaagcaacg
    57841 tttttccctt agaaaataca aatcaggaac gttttcggtc ttaataggaa gcgttttctt
    57901 gatgatgaca acaacagtag cagcagatga gctaaccaca acgagtgaac caacaatcac
    57961 gaatcacgct caacaacaag cgcaacatct caccaataca gagttgagct cagctgaatc
    58021 acaatcccca gacacatcac aaatcactcc caagataaat cgtgaaaaag agcaaccaca
    58081 aggtctagtc tctgagccaa ccacaactga gctagctgac acagatgcag caccaatggc
    58141 taatacaggt cctgatgcga ctcaaaaaag cgcttcttta ccgccagtca atacagatgt
    58201 tcacgattgg gtaaaaacca aaggagcttg ggacaagggg tacaaaggac aaggtaaggt
    58261 tgttgcagtt attgacacag ggatcgatcc ggcccatcaa agcatgcgca tcagtgatgt
    58321 atcaactgct aaagtaaaat caaaagaaga catgctagca cgccaaaaag ccgccggtat
    58381 taattatggg agttggataa atgataaagt tgtttttgca cataattatg tggaaaatag
    58441 cgataatatc aaagaaaatc aattcgagga ttttgatgag gactgggaaa actttgagtt
    58501 tgatgcagag ccaaaagcca tcaaaaaaca caagatctat cgtccccaat caacccaggc
    58561 accgaaagaa actgttatca aaacagaaga aacagatggt tcacatgata ttgactggac
    58621 acaaacagac gatgacacca aatacgagtc acacggtatg catgtgacag gtattgtagc
    58681 cggtaatagt aaagaagccg ctgctactgg agaacgcttt ttaggaattg caccagagac
    58741 ccaagtcatg ttcatgcgtg tttttgccaa cgacgtcatg ggatcagctg aatcactctt
    58801 tatcaaagct atcgaagatg ccgtggcctt aggagcagat gtgatcaacc tgagtcttgg
    58861 gaccgctaat ggtgcacagc ttagtggcag caagcctcta atggaagcaa ttgaaaaagc
    58921 taaaaaagcc ggtgtatcag ttgttgtagc agcaggaaat gagcgcgtct atggatctga
    58981 ccatgatgat ccattggcaa caaatccaga ctatggtttg gtcggttctc cctcaacggg
    59041 tcgaacacca acatcagtgg cagctataaa cagtaagtgg gtgattcaac gtctaatgac
    59101 ggtcaaagaa ttagaaaacc gtgccgattt aaaccatggt aaagccatct attcagagtc
    59161 tgtcgacttt aaagacataa aagatagcct aggttatgat aaatcgcatc aatttgctta
    59221 tgtcaaagag tcaactgatg cgggttataa cgcacaagac gttaaaggta aaattgcttt
    59281 aattgaacgt gatcccaata aaacctatga cgaaatgatt gctttggcta agaaacatgg
    59341 agccctggga gtacttattt ttaataacaa gcctggtcaa tcaaaccgct caatgcgcct
    59401 aacagctaat gggatgggga taccatctgc tttcatatcg cacgaatttg gtaaggccat
    59461 gtcccaatta aatggcaatg gtacaggaag tttagagttt gacagtgtgg tctcaaaagc
    59521 accgagtcaa aaaggcaatg aaatgaatca tttttcaaat tggggcctaa cttctgatgg
    59581 ctatttaaaa cctgacatta ctgcaccagg gggtgatatc tactctacct ataacgataa
    59641 ccactatggt agccaaacag gaacaagtat ggcctctcct cagattgctg gcgccagcct
    59701 tttggtcaaa caatacctag aaaagactca gccaaacttg ccaaaagaaa aaattgctga
    59761 tatcgttaag aacctattga tgagcaatgc tcaaattcat gttaatccag agacaaaaac
    59821 gaccacctca ccgcgtcagc aaggggcagg attacttaat attgacggag ctgtcactag
    59881 cggcctttat gtgacaggaa aagacaacta tggcagtata tcattaggca acatcacaga
    59941 tacgatgacg tttgatgtga ctgttcacaa cctaagcaat aaagccaaaa cattacgtta
    60001 tgacacagaa ttgctaacag atcatgtaga cccacaaaag ggccgcttca ctttgacttc
    60061 tcgctcctta aaaacgtacc aaggaggaga agttacagtc ccagccaatg gaaaagtgac
    60121 tgtaagggtt accatggatg tctcacagtt cacaaaagag ctaacaaaac agatgccaaa
    60181 tggttactat ctagaaggtt ttgtccgctt tagagatagt caagatgacc aactaaatag
    60241 agtaaacatt ccttttgttg gttttaaagg gcaatttgaa aacttagcag ttgcagaaga
    60301 gtccatttac aggttaaaat ctcaaggcaa aactggtttt tactttgatg aatcaggtcc
    60361 aaaagacgat atctatgtcg gtaaacactt tacaggactc gtcactcttg gttcagagac
    60421 caatgtgtca accaaaacga tttctgacaa tggtctacac acacttggca cctttaaaaa
    60481 tgcagatggc aaatttatct tagaaaaaaa tgcccaagga aaccctgtct tagccatttc
    60541 tccaaatggt gataacaacc aagattttgc agccttcaaa ggtgttttct tgagaaaata
    60601 tcaaggctta aaagcaagtg tctaccatgc tagtgacaag gaacacaaaa atccactgtg
    60661 ggtcagccca gaaagcttta aaggagataa aaactttaat agtgacatta gatttgcaaa
    60721 atcgacgacc ctgttaggca cagcgttttc tggaaaatcg ttaacaggag ctgaattacc
    60781 agatgggtat tatcattatg tggtgtctta ttacccagat gtggttggtg ccaaacgtca
    60841 agaaatgaca tttgacatga ttttagaccg acaaaaaccg gtactatcac aagcaacatt
    60901 tgatcctgaa acaaaccgat tcaaaccaga acccctaaaa gaccgtggat tagctggtgt
    60961 tcgcaaagac agtgtctttt atctagaaag aaaagacaac aagccttata cagttacgat
    61021 aaacgatagc tacaaatatg tctcagtaga agacaataaa acatttgtgg agcgacaagc
    61081 tgatggcagc tttatcttgc cgcttgataa agcaaaatta ggggatttct attacatggt
    61141 cgaggatttt gcagggaacg tggccatcgc taagttagga gatcacctac cacaaacatt
    61201 aggtaaaaca ccaattaaac ttaagcttac agacggtaat tatcagacca aagaaacgct
    61261 taaagataat cttgaaatga cacagtctga cacaggccta gtcacaaatc aagcccagct
    61321 agcagtggtg caccgcaatc agccgcaaag ccagctaaca aagatgaatc aggatttctt
    61381 tatctcacca aacgaagatg ggaataaaga cttcgtggcc tttaaaggct tgaaaaataa
    61441 cgtgtataat gacttaacgg ttaacgtata cgctaaagat gaccaccaaa aacaaacccc
    61501 tatctggtct agtcaagcag gcgctagtgc atccgctatt gaaagtacag cctggtatgg
    61561 cataacagcc cgaggaagca aggtgatgcc aggtgattat cagtatgttg tgacctatcg
    61621 tgacgaacat ggtaaagaac atcaaaagca gtacaccata tctgtgaatg acaaaaaacc
    61681 aatgatcact cagggacgtt ttgataccat taatggcgtt gaccacttta ctcctgacaa
    61741 gacaaaagcc cttggctcat caggcattgt ccgcgaagaa gtcttttact tggccaagaa
    61801 aaatggccgt aaatttgatg tgacagaagg taaagatggt atcacagtta gtgacaataa
    61861 ggtgtatatc cctaaaaatc cagatggttc ttacaccatt tcaaaaagag atggtgtcac
    61921 actgtcagat tattactacc ttgtcgaaga tagagctggt aatgtatctt ttgctacctt
    61981 gcgtgaccta aaagcggtcg gaaaagacaa agcagtagtc aactttggat tagacttacc
    62041 ggtccctgaa gacaaacaaa tagtgaactt tacctacctt gtgcgggatg cagatggtaa
    62101 accgattgaa aacctagagt attataataa ctcaggtaac agtcttatct tgccatatgg
    62161 caaatacacg gtcgaattgt tgacctatga caccaatgca gccaaactag agtcagataa
    62221 aatcgtttcc tttaccttgt cagctgataa caacttccag caagttacct ttaagatgac
    62281 gatgttagca acctctcaaa taactgccca ctttgatcat cttttgccag aaggcagtcg
    62341 cgttagcctt aaaacagctc aaggtcagct aatcccgctt gaacagtcct tgtatgtgcc
    62401 taaagcttat ggcaaaaccg ttcaagaagg cacttacgaa gttgttgtca gcctgcctaa
    62461 aggctaccgt atcgaaggca acacaaaggt gaatacccta ccaaatgaag tgcacgaact
    62521 atcattacgc cttgtcaaag taggagatgc ctcagattca actggtgatc ataaggttat
    62581 gtcaaaaaat aattcacagg ctttgacagc ctctgccaca ccaaccaaga caacgacctc
    62641 agcaacagca aaagccctac catcagcggg tgaaaaaatg ggtctcaagt tgcgcatagt
    62701 aggtcttgtg ttactcggac ttacttgcgt ctttagccga aaaaaatcaa ccaaagattg
    62761 ataacaaaac gcaaagagac aacaaatcat cccttttaac agtcggacct ttctttgaga
    62821 ttgagctggc agatgatcat ttcttaacaa aagttaaaga gttgagcaaa gtaaggaaca
    62881 gacataaaga ccataaaagc aagccagttt ggcttgcttt tatggtgtta ttgtcgtgtg
    62941 ctacgatgac tgaaaaagaa caacgaacaa tgacctcgaa tcaccaaaag gacttgattt
    63001 gatagcttcc ctatgctata ctaagcctat tctttcaaga aggactcctt ttgtggaaaa
    63061 gactgaaaaa aaggacacta atctatccaa aaactccaga tgagtagctg caaacggatg
    63121 cctctgctgt gatcaagggg ataaagcaga ctggcttgtc actacctgag caggtgtcaa
    63181 aaaaagaagc ttttggcttt gacattcaac atactgagct ttagtatttt agaacggaga
    63241 cacccccagt tttgtactca aaaagcatga acagttctgc tgatgtgaca tctgatttct
    63301 acgtgcgcag tgagccaaaa cagctgctgt ttgctatgga aaaagtggcg ccaatcgaga
    63361 tttttgagac cctaggctca aaaataaggc atagaattcc aaaggaagtc gctgccgtga
    63421 gcacaaccta agaaaaacta ttccaaaaga ctttttctgc aatttgaaat actgaatttc
    63481 agtatttttt cttttgtaac taagagcaat gaatgaggta aaaaaaggca acaatgtcaa
    63541 aaaagaaacg aaaacactat caggtttatg atggattacg ctgtgctatg acgctttgtt
    63601 ttatcagtgg ctatgtcaat gcctttacct atatgaccca aggcaaacgt tttgcaggtg
    63661 ttcagacagg caaccttttg tcatttgcca ttcgcttgtc agaacagcaa ctgaaggagg
    63721 cactgcaatt tttacttccc atgatagttt ttatgcttgg gcagtccttt acttatttca
    63781 tgcaccgctg ggccactaaa aaagggctcc actggtactt attatcaagc gttatcttaa
    63841 cagggattgc ttttggaatg gccctattca cgccttttct tccttccaat gttacggtag
    63901 cagctttagc cttttttgcc tctattcagg ttgatacgtt taaaacctta cgaggagcta
    63961 gctatgctaa tgtgatgatg acaggaaata tcaaaaatgc cgcctattta ctaaccaaag
    64021 gcttgtacga aaaaaatcac gaactaacac atatcggacg caacacctta atagtcatct
    64081 tggcttttgc tgttggggtg gtttgttcga cgttgctttg catagcttat ggcgagtatg
    64141 ctttgatgcc tattttaatg cctttactct atgtcaatta cctgttggct caggaatttt
    64201 atcacattca aaccaaaatc aaaccgatta aaagaactta acggacttgt ggagaaagaa
    64261 agttcattta gggtaagttt ttacttaccc tccgttgatt tgctggtttt gctgcccctt
    64321 aaaatatgat ataatagacc attgatagct gttacttaac agaaggctga taaaaaaggt
    64381 tccattagcc ttgagggttg aatttaaaca ggaaaaaacg aaatcctaca ctatgcatct
    64441 caatcgtact ttcatttgag tatggttctg aaaggaaact atgatgaaaa aaccatttta
    64501 cattacgaca cccatttatt acccatctgg gaaattacac attggttctg cctatacaac
    64561 tattgcttgt gatgtcttgg cacgctacaa gcgtctgatg ggccatgagg tcttttacct
    64621 cacaggacta gatgaacacg gacaaaagat tcaaaccaag gcaaaagaag ctggtattac
    64681 acctcaaacc tacgttgata acatggcaaa ggatgtcaaa gccctttggc aattgctaga
    64741 tatttcctat gacacattta tccggacaac ggacgattac cacgaagagg tcgttgctgc
    64801 tgtttttgaa aaattactgg cgcaagatga catttacctt ggtgaatact ctggttggta
    64861 ttctgtctct gatgaggaat ttttcactga aagccaacta gaagaagttt ttagagatga
    64921 agacggtaag gttattggag ggattgctcc ttcaggtcac caagtagagt gggtatcaga
    64981 agaatcttac ttcctacgcc ttagcaagta cgctgaccgc ctcgtagcct tctttaaaga
    65041 gcgacctgac tttatccaac cagacggtcg tatgaatgaa atggtgaaaa actttatcga
    65101 gccaggccta gaagatttgg ctgttagccg tactaccttt acatggggtg tacctgttcc
    65161 atcagaccca aaacacgtgg tttatgtctg gatcgatgcc ctcctaaact acgcgacagc
    65221 tcttggttat ggtcaagcta atcacgctaa ctttgataaa ttctggaatg gaacggtttt
    65281 ccacatggtt ggaaaagata tcttgcgttt tcatagcatc tactggccga tcttactcat
    65341 gatgcttgat ttaccaatgc cagaccgctt aattgcccat ggttggtttg tcatgaaaga
    65401 cggtaaaatg tctaaatcaa aaggcaatgt ggtctatcca gaaatgttag tggagcgctt
    65461 tggacttgat cctcttcgtt attacctcat gcgttctttg ccagttggtt cagacgggac
    65521 ctttacccct gaagattatg tgggtcgtat caactatgag ttagccaacg accttggcaa
    65581 tttattgaac cgtaccgttg ccatgatcaa caagtatttt gacggcacgg tgccagctta
    65641 tgttgacaat ggaactgcct ttgatgctga cttcagtcaa ctgattgatg ctcagctagc
    65701 agactaccat aagcacatgg aagctgtaga ctacccacgc gccttagaag ccatttggac
    65761 catcattgct cgtaccaaca aatacatcga tgaaaccgct ccttgggtgc tcgctaaaga
    65821 agatggtgac aaagctcaac tagccagtgt catggcacac ttggcagcta gcttgcgcgt
    65881 ggtcgctcat gtgatccaac cctttatgat ggaaacatca gctgctatca tggcccagct
    65941 tggcttagcg cctgtttctg acttatcaac acttgctcta gcagattttc ctgccaatac
    66001 aaaggtcgtt gccaagggca caccgatttt cccacgtctt gacatggaag ctgagattga
    66061 ctacattaaa gcccaaatgg gtgacagctc agctatttcc caagaaaaag aatgggtccc
    66121 tgaagaggtt gcgctcaaat ctgaaaaaga cgtcatcaca tttgaaacct ttgatgctgt
    66181 ggaaatccgt gtggcagaag tcaaggaagt gtcaaaagtg gaaggttcag aaaaattgct
    66241 gcgctttaga gtagatgcag gagacgggca agaccgtcaa atcttgtcag gtattgccaa
    66301 atgctacccc aacgagcaag aattagtggg taaaaaacta caaattgttg ctaacctgaa
    66361 accgcgtaaa atgatgaaac aatacatcag ccaaggcatg attttgtcag cagagcatgg
    66421 agatcagcta acggtcttaa ccgttgattc ctctgttcca aatggaagta tcattggctg
    66481 atgctgacct attattcaaa aacctaagca agaatatgtg cttaggtttt ttgattgcct
    66541 tcaagaaaga tgaataacga gatgggtgat atggcatcaa aagcataact atcctaggac
    66601 ctgtcctagt aagattgctg tgcttttgac aagtgaacag agaggtctta aactatatct
    66661 tgtcataaaa aagattgcaa aacactatat cttgtgttat tatggttttt ataaaagtta
    66721 agcgtgctta actttagcca aacaaaagag gacactagag cgtgtcccac aagacagttg
    66781 agcccttcgc ttttttagta gagtaggagt gctcaagtca aaaagagaca gcccatcaaa
    66841 ccattgctgt ttagcaggtc tttttgtgtt gctcaaaaaa cagttcctgt ctgtttggcg
    66901 tctagtgatg acttaggctt agcgctacta gacttttgtt tgaaaaatac ctcaagcctt
    66961 gaaggagaca aatgacccaa cattattatg aacgttcgca atccccaatt gaatacgccc
    67021 tatctgaaac acaaaaacag ttgcgctcca tcaattggaa ttaccttaat gatgacaaag
    67081 atttggaagt gtggaaccgt gtcactcaaa atttttggtt gcctgaaaag gttcctgttt
    67141 ctaatgattt aaattcttgg cgctccttgg gtgaggattg gcaacagctc atcacaagga
    67201 cctacactgg gttgacctta ctagatacag tacaagcaac ggttggtgat gtggcacaaa
    67261 ttcagcattc acaaaccgac cacgaacaag tcatctatac gaactttgcc tttatggtgg
    67321 ggattcatgc ccgctcttac gggacgattt tttcgaccct ttgcagcagc gagcaaatcg
    67381 aagaagcaca tgaatgggtg gtctcaacac agagcttgca agaccgttcc cgtgtcttga
    67441 ttccttacta tacgggtgat gaccctttga aatcaaaagt agcagcagct atgatgccag
    67501 gatttttgct gtatggcggc ttttaccttc ctttttacct atcagcacgt ggtaaaatgc
    67561 caaacacctc tgatatcatc cgcctgattt tacgcgacaa agttattcac aactattaca
    67621 gcggttacaa ataccaacaa aaagtagcac gtcttagccc agaaaaacag gctgaaatga
    67681 aggcctttgt ctttgacttg ctctatgaac tcatcgacct tgaaaaagct tacttgagag
    67741 aactgtatgc aggctttgat ttggcagaag atgctatccg ttttagcctt tataacgctg
    67801 gaaaattcct tcaaaattta ggttatgatt cgcccttcac agatgaagaa acccgtatct
    67861 cacctgaagt atttgctcag ctatcagcgc gtgcagacga aaaccatgac tttttctcag
    67921 gcaatggctc atcttatgtg atggggatca ccgaagaaac cacagatgac gattgggagt
    67981 tttaagaaat ggcagagctg attattgtgt atttttcatc taagtccaat aacacccatc
    68041 gcttcgtcca aaaattaggc ctgcctgctc agcgcatacc agtagataat aggccacttg
    68101 aagtttcaac ccattacctt ttgattgtgc ctacctatgc agctggtggt tcagatgcca
    68161 aaggagccgt tcctaaacaa gtgattcgtt ttttgaataa tcctaacaat cgtaaacatt
    68221 gtaagggagt gatctcttca ggaaatacca attttggcga tacctttgcc ttagcaggcc
    68281 ctatcatttc tcaaaaattg caggtccccc tattacacca atttgaacta ttaggcactg
    68341 ctacagatgt caaaaaggta caggcgatct ttgcccgctt aaagcatcac acacacgaca
    68401 agcaaaaaca aatcaacaac ctgattacag aaaggacaca cccatgtcac aaaccaatgc
    68461 gtcatacctc tcattaaatg cactgacccg ttttaaaaaa ccagacggca gctaccattt
    68521 tgatagcgat aaagaagctg ttaggcgcta cctggaagaa catgtctctc ccaatcaaat
    68581 ggcttttaac tcactagaag ataagctagc ttacctcatc aatgaagggt attatgagca
    68641 ggccattttt gatgcctatc ctaacgacct tatcaaggag gcctttcatt atgcctatca
    68701 acaaggctat cgctttttaa atctcatggg cgctatgaaa ttttaccagt cctatgcctt
    68761 aaaaaccttg gacggtaagc agtatctaga aacatttgaa gaccgtgctg tgatgaatgc
    68821 actcttttta gctgatggag atcaaacctt tgtctttgac gtgattgatg ccatcttgca
    68881 ccgacgcttt caaccagcta ccccaacgtt tttaaatgcc ggaaaaaaac gccgtggcga
    68941 atacatttcg tgctatcttc ttcgtgtcga agacaatatg gaatctatct ctcgcgccat
    69001 tagcaccagc ttgcaactct caaaaagagg aggcggagtc gccttgtgcc tcaccaacct
    69061 cagagaaatc ggagcaccga taaaagggat tgaaaatcag gcaacaggca tcgttcctgt
    69121 catgaaacta ctagaggact ctttttccta tgccaatcaa ctaggtcagc gccaaggagc
    69181 aggtgcggtt taccttcatg cccatcatcc tgaggtcttg acctttttag acaccaaacg
    69241 tgaaaatgcc gatgagaaaa ttcgcattaa gtccctagca ttgggacttg tgatcccaga
    69301 tattaccttc cagttagcca aagaaaacaa agacatggct ctcttttcac cctatgatat
    69361 caagcgtgcc tatggcaagg acatgtcaga catctccatc acagaggaat acgataaact
    69421 gctagccaat ccagccatca aaaagaccta catcagtgct agaaagttct ttcagttaat
    69481 tgcagagcta cattttgagt caggctaccc ttacctcttg tttgatgaca cggtcaataa
    69541 gcgcaatcct catgccaaaa aaggcagaat cgtcatgtct aacctgtgtt ctgaaatcgc
    69601 tcaagtcagc accccaagca ctttcaaaga agatttgagt tttgaaacca ttggagagga
    69661 tatctgctgt aatttagggt ctatcaatat tgcccaggct atggcagatg cgccacactt
    69721 tgaacagctc atcacaacga gcatcagagc acttgatcgt gtctctagag tgtctgacct
    69781 gaattgtgcg ccttctgttg agacaggcaa tgcagccaac catgcagtag gattaggcgc
    69841 catgaaccta catgggtttt tggcaaccaa ccacatctac tatgatacaa aagaagccgt
    69901 tgactttaca gatctgtttt tccatgccat ggcctattat gcttttaaag cctcttgcca
    69961 attagccaaa gaaaaaggcg cttttgcagg attttcgtta tcaacctatg cagatggcac
    70021 ttattttgcc aagtatttgc aagaagatgc caagccacaa acagccaagg ttgccacatt
    70081 gttgcaagat tacggcttca cattgccaac ggtggcggat tggcaagccc tagtagcaga
    70141 tatcaagcag tttggtctag ccaatgcgca cttgctagcg gttgctccga caggctccat
    70201 cagctactta tcatcctgca ctccgagtct acaaccagtc gttgctcctg ttgaggtccg
    70261 aaaagaaggt agcctgggca ggatttacgt ccctgcctat cagattgacc aggctaacta
    70321 tgcttactat gaacgtggtg cctatgaggt cggcccaaaa gccatcatcg acgttgtagc
    70381 tgctgcccaa aaacacgttg accaagccat ctcattgacc ctgtttatga ccgatcaagc
    70441 gaccacacgt gaccttaacc gctcctatat ccaagctttt aagcaaaact gtgcatcgat
    70501 ctattatgtg cgagtgaggc aagacgtcct agcaggcagc gaacagtatg acgaggatag
    70561 tcttgtgaca gctcctggag ctagtgatga gaccaccaca gagtgtcaaa gctgtatgat
    70621 ctaacagcta ctagaaagct ctcgtgtccc ctatcacatg cataggatca gtgcactcga
    70681 cctttcaaga caagcaagca tcagctcttg cttgtctttt tttggcctta aagcccgtta
    70741 gtctgctgct atgcgaggct ttttttgagc attagaacgt caaaaaaaag gacatggagt
    70801 ccttttttgg tgatcggtgt tgaggccgtc acaaactgcc cttgaaatac gcttctatgt
    70861 ggagcttttt ttggtcttgt gacacgtaag ctccaacgac ctccagctga cagcctcttg
    70921 gaaacaagag ctcaacctct gaaggcacag ccgaataagg ctcgacaaag gctgccttgg
    70981 cccctttttt gacacagatg cgcacctcca ccggtcgatg ggtcatggcg ccgtttttca
    71041 aggctgtcgt gctcataaaa ctgtgcttgg tgtagcgtgt gccaagcttg atcttacaaa
    71101 ggatatgagg gtcaaactga tggttacggt agtaagacgt gagatcagcg tgtgaaacac
    71161 cgatatcacg caaaaacgtc tcgtacacat agcggtatac cacaatgttc cacgggatga
    71221 ctagccggtg agtcgcagca tcgagctggg ccacctgatc ccttagctca ggcgtgagtt
    71281 ggctgagctc acctttggtc ttgtctaggc tggtgttgat aggggctgcc tgctggcagg
    71341 tataagcagc catcgcctct tgctcagccc ttgggtagac gagacccttg ccccagcgct
    71401 ttttaatcag tgtctcagcg cccttttgat ccgaaaaggt aaaataagca ggcgtcccct
    71461 cacaaaccgc ccgctcatag tgctcacaga caaaaagctc gaccaagccc tcagtttgcc
    71521 agactagact aaaacagcta agaagaagga tcatagccag ttgatagcgc ttttttagca
    71581 tagttccccc tgacaccagc ccaaaaggct gacccttccc ctaggccttt tggctagctc
    71641 atgataccac cagtttctca gacaggctaa tctttttgtc atctctttct ccctaaacag
    71701 actctcttat catgatatta tgctattatg aacgatttgt caatccatag caaccgtttt
    71761 ttagccagat aagtaagctt ttgacctaga ggcagacaag agtggcagta cctgccgttt
    71821 gctgtggtgg ctaataagga ctaacataaa atatcaaacg ctttcaaaaa cagctcctaa
    71881 gcttaaaaaa gctgatgaac aattttttga gtttaagaga gattgccatg attttctaat
    71941 catttgatgt ttaaaatgat aaaaacatga acttgaaatg aaagaatacg agtagtaaac
    72001 taaaaatata tcaaaaataa tgaaatggag tgattttatg aaaacaaaat caaaacgctt
    72061 tttaaaccta gcaacccttt gcttggccct actaggaaca actttgctaa tgacacgtcc
    72121 cgtaaaggcg gataatgata ctagggagtc tcaagagcgc gtagaccaaa gaatagaaga
    72181 tccttatgat gatggaaaaa atgctgggag aaaggatggt tatgaatcag ggaatcataa
    72241 gggaatctct gaagagcctc caactaaaac tcctgaacct ccgactaatc cttatagccg
    72301 tgatagggtg aaaagcaaga agtatagaga tggttatcag gaatggtatg tctatggata
    72361 ctatgaaggt tggcatagag caaatgatga ggataaaaat aaagagtctt ctgaccattc
    72421 tcgagatcag gatttagaag gtacagaaca gacagatgga caggatgagg ataaaaataa
    72481 agagtcttct gaccattctc gaaatcagga tttagaaggt acagaacaga cagatactga
    72541 atattcagca attatcagta cattgtatgg aattgctgga gttgtattgg aatatgtgct
    72601 atcttggttt agtatctaag atttagtttt ggttactgga taatggttta aatatttatt
    72661 attatctaaa aatggcgtga tcaaattttg atgatttggt taatattgtt tagaacagac
    72721 tgaagacaaa gctcttagta actaaattct aagggctttg tcttcagtct gaggcacctt
    72781 acggggtgtc ttttattatt taggtggctt aatgaattgg ttaaaatctt tttagtttag
    72841 taaaattgct atttaaggtt agccacctct cgtatggtca cagttgatga attatgctat
    72901 agtatagaca taaaaaatag ttcaaatccc ttcttgcctg ttggtggatt ttgaactgaa
    72961 agcctctctg attgcagttg gtaggctttt ttgatgcttt ttcgtacttt ttttatttat
    73021 tacgctaaaa aatgttatac ttgatgaaga aaaaggagag tttagaacgt taagatacct
    73081 cacagcagat tgatagagga tatggaaaaa ggttagcttt cccaagagat gccgtttggg
    73141 aatggtataa caataactgg cagaagttat aagtaaaaca agaacaaatt aactcagatg
    73201 atttttagac gttcccacgc gtgtgcgaat taattggaaa aaaatgagaa aatacgatat
    73261 acaaaaaagg agaacaatat gacatttgaa gaaattttac caggtttaaa agccaagaaa
    73321 aaatatgtac gtacaggttg gggtggcgct gaaaattatg tgcagttgtt tgataccctt
    73381 gaagtggatg ggaaagtact acaggcgacg ccttattttc tgattcatgt tactggtgaa
    73441 ggtgaaggtt tttccatgtg ggcaccgaca ccatgtgatg tgttagcaga ggattggatc
    73501 gaggtcaatg actaaagttg ttttagtgac gggctgtgct agtgggattg gttatgcaca
    73561 ggcccgctat tttttgagac aagggtatca cgtatatggt gtggataagt cggataagcc
    73621 ggacttaagc ggtaactttc actttatcaa attggattta tcctctgagt tatccccact
    73681 ctttaaagtg gtccccagtg ttgatatttt gtgtaatact gcagggattt tagatgccta
    73741 caagccactt ttagacgtta gtgatgaaga agtggaacac ctatttgata ttaatttttt
    73801 tgcgacggtg aagttaacac gtcattatct tagacgtatg gtggaaaagc agtcaggtgt
    73861 tatcatcaat atgtgctcaa tagcaagttt tatagcgggt ggtggtggtg ttgcctatac
    73921 gagttctaag catgcgcttg cgggcttcac gcgtcaattg gctttggatt acgccaaaga
    73981 tcagattcac atctttggta tagcgccagg tgctgtcaaa accgctatga cggctagcga
    74041 ctttgagcct ggtggcttag cagaatgggt agctcgtgag acgccaattg ggcgttggac
    74101 tgaaccagat gaagttgctg aattaacggg atttcttgcg tcaggaaaag cgagatcaat
    74161 gcaaggtgaa attgtcaaaa ttgacggtgg ctggactttg aaatgatcac atgccttagc
    74221 ttgagctggc gcagtaagcc ctagaggtgt gatgagtcaa acagtcaaag gagatgaaca
    74281 aatgaaatta gcggttttgg ggacaggtat gattgttaag gaagttttgc ctgtcttgca
    74341 gaaaattgat ggtattgatc tagttgctat cttatcaaca gttagaagtt taaagacagc
    74401 taaagacctc gctaaggcat atcacatgcc tctagctacg agtgaatatg aggctgtctt
    74461 aggcaatgag gagattgaca cggtctatat tggactgcca aatcacctgc attttgccta
    74521 tgctaaggag gctcttctgg ctggtaaaca tgtcatttgt gaaaagccct ttaccatgac
    74581 agcaggagaa ttagatgaac tggtggtaat cgctaaaaaa cgaaagctta ttttgttaga
    74641 agcgattacg aatcagtatt taaacaacat gacctttatc aaagagcatc ttgaccaact
    74701 tggcgatatc aaaattgtag aatgcaatta ttcacaatat tcttcacgct acgatgtctt
    74761 caaacgaggt gatatcgcgc cagcttttaa tcctaaaatg ggtggtggag ctttacgtga
    74821 tttaaacatt tacaacattc attttgtggt aggattattt ggtcgcccta aaacggttca
    74881 atatttagcc aatgtcgaaa aaggcattga cacatcaggc atgcttgtca tggactatga
    74941 gcagtttaaa gtggtgtgta tcggggccaa agactgcact gcggaaatca aaacaaccat
    75001 ccaaggtaat aaagggtcac tggcagtgct tggagcaaca aatacccttc ctcaggttca
    75061 gttaagtcta cacggtcacg aagcacaagt ggttaatcac aacaagtatg accaccggat
    75121 gtatgaagag tttgtcgctt ttagggacat gattgaccaa agagactttg agaaagtgaa
    75181 tcaggctttg gagcatagcc gagctgtcat ggctgtgttg gagcgagctg ttcattcgtg
    75241 atggtaatct ggtagccatt gccttttgtg cagttgctat ggtaatggtt gaaagacgtg
    75301 ttttcacgag ggttaacccc ctcgtgcttt tttggtaaaa ataacttgtt caggatttgg
    75361 gccttctttg tgagatgaga gatgcctgac gaattgattt gattaaaata atgataaagc
    75421 caaacgattt aagaaatgac cgttcggaaa ttctgcccca aaaggtctct agaagcagta
    75481 aaatcgaatt tgtaagcgtt gacactgctg cataactctg ttacactaag agaatgtcat
    75541 gacaaaaatt acagtgtagg agtttaattg tttatggaag aggattataa caaaagagaa
    75601 cctgagaagt ttacgcaatt tctgcgccgt caaaaggtcg tcttttttgt cgcatttttt
    75661 ggttatgtgt gtgcttactt ggtacgcaac aatttcaaac taatgtcaaa cactattatg
    75721 gtccaaaacg gttgggacaa ggctcaaatt gcgaccttgt tatcgtgttt gaccgtttct
    75781 tatggcttag caaaattcta tatgggggcc ttaggggatc gtgttagctt gagaaagctc
    75841 ttttcgatca gcttgggtgc aagcgctttg atttgtattt taattggttt tttcaatagt
    75901 tcaatggtag tgttagggat actgctagtc ttgtgtggtg ttgtacaagg tgccttggca
    75961 cctgcctcac aagccatgat tgccaattat tttccaaata aaacacgcgg cggagccatc
    76021 gctggatgga acatttctca aaacatggga tcagccctct tgccattaac catcgccttg
    76081 ctcaccagta tgggcttggt ggtaccagct aatggcaata ttttacttgc ctttttaatc
    76141 cctggtgttt tagtgttctt gtttgctttg tgttgctgga agcttggcgg tgataatcct
    76201 gagtctgagg gacttgactc tcttcgaacg atgtatggtg atgcgggcga atcagctgtt
    76261 gccagtgaag aagaaaagca taacctgtct tattggcaac tcatctggaa atacgttttt
    76321 tgtaacccgt cgctcttact tgttgctgct gtcaatgtgg ccctttattt tgttcgtttt
    76381 gggattgaag actggatgcc gatctacttg tcacaagtag ccaatatgtc agaggcccat
    76441 attcattttg cgatttcaat gttagagtgg gtagctattc caggctcgct ggtatttgcg
    76501 tggttagcgg ttcgttatcc taataaaatg gccaagattg gggctattgg gctttttgtg
    76561 ttagcggcta ttgtgtttgt ctatgaacgc ttgactgcca caggtgctcc aaactatttc
    76621 ttgttgcttg ttattgcagg tattttaggg tcattgattt atggcccaca gttgatcgtg
    76681 aatattttaa caatcaactt tgttccttta aacgttgcag gaacagcgat tggttttgta
    76741 ggagtaacag cttatctcat cggcaatatg ggagcaaact ggctgatgcc gattttggca
    76801 gatggttttg gctggttttg gtcatatatt gtcgttgcag ccttatctgc tttttcagcg
    76861 gttggttatt taattttagc caaacgtgag gaagaaatca tcaaagatta gctaggcaaa
    76921 tgcctaagaa agacagactt attgctgaag tcctgtcttt tttagtcatc acaagccgca
    76981 agtaacacta taaaagacaa gaaaatgcta gggtgtttca ggaaaaaaag agaaaatatg
    77041 ctataatgag aaggtattta aattatatag taaggaaaaa caaatgacaa attatgccat
    77101 tattttagca gcgggcaaag ggactcgcat gacttctgat ctcccaaaag ttcttcataa
    77161 agtatctgga ctaaccatgc ttgagcatgt ttttcgtagt gtaaaagcga ttagtcctga
    77221 aaaatccgtg acggttattg gtcacaaatc agaaatggta cgtgctgtct tagcagatca
    77281 atcagccttt gtccatcaaa cagagcagtt aggaactggc catgccgtga tgatggcaga
    77341 aacacaacta gaaggactag aagggcatac cttggtgatt gcaggagata ctcccttgat
    77401 cactggagaa agcctgaaga gtctgattga ttttcatgtg aaccataaaa atgtcgccac
    77461 tattttaaca gctacggctc aagatccatt tggttatggt cgtattgttc gcaacaaaga
    77521 tggcgaagtg atcaagattg ttgagcaaaa agacgccaat gagtatgagc aacaattaaa
    77581 agaaatcaat acaggaactt atgtgtttga taacaagcgt ctctttgaag cgctcaaatg
    77641 catcactacc aacaatgctc aaggagagta ttacctgact gatgttgtga ctatttttag
    77701 agcaaacaaa gaaaaggtag gagcctatat cctgagagac ttcaatgaaa gtcttggtgt
    77761 taatgatcgt gtggccttag caacagctga aacagtgatg cgccagcgca ttacccaaaa
    77821 acatatggtc aatggggtga ctttccaaaa tcctgaaacc gtttatattg aaagcgatgt
    77881 tgagattgct ccagatgtcc ttatcgaagg aaatgtgacc ttgaaagggc gtacacatat
    77941 cggctcagga actgtcttga cgaatggtac ttatattgtg gattctgaaa ttggtgataa
    78001 ctgtgttgtt actaattcaa tgatcgaatc atctgtttta gctgcaggag ttacggttgg
    78061 cccttacgcc caccttcgac caggaacgac cttagatagg gaagtccata tcggtaactt
    78121 tgttgaggtc aagggttctc acattggtga aaaaacaaag gctgggcatc tgacttatat
    78181 tggaaacgct caggttgggt cttcagtcaa tgttggggct ggaaccatca ctgtcaacta
    78241 cgacggccaa aacaaatatg aaacagtcat tggagatcac gcttttattg ggagcaactc
    78301 gactctcatt gcacctttgg aagttgggga tcacgcttta acagcagcag gttcaacgat
    78361 ttcaaaaacg gttcctatcg atagcattgc tattggtcgt agccgccaag tcacaaaaga
    78421 aggttatgcc aagcgcctag cgcatcaccc aagtcgaagc aaataattca agatctattt
    78481 agtaaggagg ccaggcatga aatttgaaga aaaaacgctt aagagacaaa cagtttttga
    78541 tggtcatatt tttaaagttg ttgtggatga tgttgaactt cccaacaatc tggggcaatc
    78601 caagcgagaa ttaatttttc atcgtggtgc cgttgctgtt ttggctatta ctcctgaacg
    78661 taagattctc cttgtcaaac aataccgtaa ggctattgaa cgtgtctcat acgagatccc
    78721 agcgggtaag ctagagattg gtgaggaagg ctcaaagcta aaagctgctg cacgtgagct
    78781 agaagaagaa acagcctata cggggacatt gacgtttttg tatgaatttt atacagcgat
    78841 tggtttttgc aacgaaaaaa tcacactttt cttagcgaca gacctaacac aagttgccaa
    78901 tcccaaacct caagacgacg atgaagttat cgaggtctta gagttgacat atcaagagtg
    78961 catggactta gtcgctcaag gtaaacttgc tgacgctaaa acgttgattg ctttgcaata
    79021 ctatgcctta cattttggag gtgagcagtg atgggaaggc cattgttgac cgatgatatc
    79081 atcgaaaaag cgagacgaat ggaaacattt gagtcagatg atgctgtaga ctttgacaca
    79141 aaagtaatga cgctaccaga aaaagatgat aaagcacgca tttataaaag ccgtcggatt
    79201 gaaaatgcca agcgcagcca attgcaatct aaattaaatg tgattttgat agctgttatg
    79261 ctgttaattg ccatcttggt atatgctatc ttttatcttt aaaaaaacgt aaggaaatga
    79321 tatgaaaata ggaattattg ctgctatgga ggaggagttg tccctgctct tagcaaatct
    79381 tttggatgct caagaacatc aggtgctttc aaaaacttac tatacgggtc gttttggcaa
    79441 gcatgagctc attttggtac agtcaggtgt tggaaaagtg atgtctgcta tgacagttgc
    79501 gatcttggtt gagcatttca aagcccaagc tattatcaat acaggatcag caggggcagt
    79561 cgcttcacat ttagcgattg gagatgtggt ggttgcagat cggttagtgt atcatgatgt
    79621 ggatgctact gcatttggtt atgcttatgg tcaaatggct ggtcaaccat tatactatga
    79681 ttgtgatcca cagtttgtgg ctatcttcaa acaagtccta aaacacgaaa agacaaatgg
    79741 ccaagttggt ttgattgcaa caggagacag ttttgttgct ggtcaggaca agattgacca
    79801 gatcaaaaca gcttttagcg acgtgttagc agtagaaatg gaaggcgcag ctattgctca
    79861 agcagcacat actgcaggga aacccttcat cgttgttcgt gcgatgagtg ataccgcagc
    79921 gcatgatgcc aatattactt ttgatcaatt tattatagaa gctggcaagc gttcggccca
    79981 gatattaatg acatttttag aaaacttacc tgtttaactc accttatcgt gagacaatta
    80041 gctggataat ctctatttta ggagtctggt cacttcttgt tttgaaacct aaaaataaga
    80101 attgcaatca cttgaccaaa cgctataata ggttaagtaa cgatagatta ctaaaaggag
    80161 tctaaaaatg acactaaaaa aacactatta tcttctcagt ctgctagctc ttgtaacggt
    80221 tggtgctgcc tttaacacaa gccagagtgt cagtgcacaa gtttatagca atggaagata
    80281 tcgtcaaggt ttgactgatg aaaaatcaaa gctgcaatat agtaaagaca acgccaaact
    80341 tcaattgaga aatatcctta acggctacca aagtgaccta gggagacact actctagcta
    80401 ttattactac aacctaagaa ccgttatggg actatcaaaa gagcaagaga ttgaaaaata
    80461 ttatgaagag cttaagaaca agttacatga tatgtacaat cattattaag ttaaaggctt
    80521 aaaaatggag actagcccct caaaaaaaga ggccacactc atttaaattt aaatgagtgt
    80581 ggcctctttt tgaggagacg caaggggtta aagggctgtg acatagagtt gcttagcaat
    80641 attttcaggg atgacaagtt ccttgtcgcc ataacaaatc gtataggttt ttgcaaaggt
    80701 atcaatttga gttaaggtta gctcggtatt gatactcagg tgatgtgctt ctagatactg
    80761 gattaaatca aagtggtcgt ggattctgct taggcgaaac cgtcccaact ccgtgatggt
    80821 gttgagagtt gtagtgttca tttcgacaag aggctgacca tagcgaggaa tagtccctcc
    80881 gtgtgggcag aaatctggaa aatcaaggat cttgtctaaa cggtcgataa aggtgtctga
    80941 gacagtgtgc tctaagactt cagcttcttg gtgcacttct tgggtattat agcccagctg
    81001 gtgaatcaaa aatacctcaa tcaagcggtg tttgcggtag aggttagcaa caagagcata
    81061 gcctttgtct tttagcaaat agccttttgc tttatctttg acaatccagc cttgtgaaat
    81121 cattttttta atcatctctg aaacggcagg tgccgaaacg tgcatctttt ctgcaaccat
    81181 tttatttgta atcttgggtt cttgttctcc aatttcatag atacatttca agtaatcttc
    81241 tttattaggc gtcatatgtt tggcctttct cttatttata atgattatta tatcagaatt
    81301 tttaggaaaa agcttgacaa aaagcctaaa agaggatatc cttatagcat aattaactaa
    81361 acttaattaa ataaataata tatcctaagg agagaaatga tgggaaagag aatgagcctc
    81421 attttgggtg cttttttatc tgtttttctt ttagtagctt gttcgtcaac tggcactaaa
    81481 actgctaaga gtgataaatt aaaagtcgtg gcaaccaatt caattattgc cgacatgaca
    81541 aaagctattg ctggtgataa aatcgatctg cacagcattg tgccaatcgg tcaagaccct
    81601 catgagtacg aaccattacc agaagatgtt gaaaaaacaa gtaatgctga tgtgattttc
    81661 tataatggta tcaatctaga agatggtggg caagcttggt tcaccaaact agtgaaaaat
    81721 gctcaaaaaa cgaaaaacaa agattacttt gccgtgtctg atggcattga tgtgatttac
    81781 ttggaaggtg caagcgaaaa aggaaaagaa gatccacatg cttggttaaa tctcgaaaac
    81841 ggaatcattt attcaaaaaa cattgccaaa caattgattg caaaggatcc taaaaacaaa
    81901 gaaacttatg aaaagaacct aaaagcttat gtggctaaat tggaaaaact agacaaagaa
    81961 gccaaatcaa aatttgatgc tattgcagaa aataaaaaat tgattgtgac tagtgaaggc
    82021 tgcttcaagt acttttcaaa agcttacggt gtcccatctg cttatatctg ggaaattaac
    82081 accgaagaag aaggaacacc agatcaaatt tcatcattga ttgaaaaact aaaagtcatc
    82141 aagccatctg cgctttttgt agagtcaagt gtcgatagac gccctatgga aaccgtttct
    82201 aaagatagtg gtattcctat ttattctgag atctttacag attcaattgc taaaaaaggt
    82261 aaacctggcg atagttatta tgctatgatg aaatggaacc ttgacaaaat ttctgaaggt
    82321 ctagcaaaat aagataacaa taaagcacag cgattttagt gttgtgcttt gttttattta
    82381 tgtaaaggag acaaaatgat tacaactaac aatctttgtg tgacctacga tggcaacagt
    82441 aatgctttag aagcgattaa tgtgacaatt gaaggtcctt ctatcgttgg tattattggt
    82501 cctaatggag ctggaaaatc aacctttatg aaagctattt taaatcttat tgattatcaa
    82561 ggtcacgtaa cggttgatgg caaagatggt cgtaagcttg ggcatacagt agcttacgta
    82621 gaacaacgaa gcatgattga ctataatttt cctattactg ttaaagaatg tgtggcgcta
    82681 gggacttata gtaaattagg cctttttcgc cgagtaggaa aaaaacaatt tgagcaggtt
    82741 gataaggttc tcaaacaagt tggtttagaa gactttggcc atcgaccgat aaaatcctta
    82801 tctggtggtc agtttcagcg gatgttggtt gcgcgttgct tgattcaaga atcagactat
    82861 attttcttag atgaaccgtt tgttggcatt gactcggtca gcgaaaaaat cattgtagat
    82921 cttttgaaag agctcaaaat ggctggcaaa acgattttaa ttgtacatca tgatttgagc
    82981 aaagtagagc attattttga caaactcatg attttaaata aacatttggt ggcttatggc
    83041 aacgtttgtg aggtatttac tgttgatacc ttgtcaaaag cctatggcaa tcatttgatt
    83101 ttaggaaagg agatggtgta aatgtctatg aaattttttg agggcttgat gtcataccac
    83161 tttttacaaa atgcactgat aacggctgta gtcattggta tcgtctcagg tgctgtaggg
    83221 tgttttatta tccttaggtc aatgtctctt atgggtgatg ccatctcaca cgctgtttta
    83281 ccaggggttg ctttgtcatt tattttagga gtcaattttt ttattggagc gattattttt
    83341 gggttattag cttctgttat tattacttat atcaaggaaa actctgtcat taaaggagat
    83401 acggctattg gtatcacctt tagctctttt ttggcactgg gagttatctt gataggggta
    83461 gccaatagtt cgacggactt atttcatatt ttgtttggga atattttagc tgtgcaagat
    83521 agcgataagt ggattactat tggtgtttcg atttttgttt tagtggttat tagtctcttt
    83581 ttcaaagaac tattattaac atcatttgat cctatcttag ccaaatcaat gggtgtgaag
    83641 gtcaatgcgt atcattattt gttgatggtc ctattaactt tagtggctgt tacggcgatg
    83701 caaagcgtgg gtactatctt gattgttgcc ttactgatta cgccagcagc gacagcttat
    83761 ttatatgcta atagcttaaa agtaatgtta gtgatgtcat ctttactagg tgctttagca
    83821 tcggttttag ggctttattt gggctatacc tttaatgttg ccgcagggtc aagtatcgta
    83881 ctgacttctg cgatgatgtt tttgatcagt ttctttgttt cacccaagca aggctacctc
    83941 aaaagatgga tgcaaaaaaa agaaaaaaca ccttaaactt ttcgctttaa acaccttagt
    84001 ggtttgcaaa tagtggcaaa taacatcaaa gggtgttttt tatatgtcat caaaagacca
    84061 taaaaaacct tatcaaacca aggtatttag cctattatct gataaggttt tttaagcatg
    84121 atttagtttt taaagcgata atctttgaca atgtcaattg aggtaatcgt aatgtcttgt
    84181 tttggtttat cattttggtt gatagaagtc gcggcaattt tatcgacaac atccatacca
    84241 tcaatgactt gaccaaatac agtataaccg ccatctaagc ttggattgcc gccatgctca
    84301 taggcagaga tgataggttt tgggtagttg gtacttgata atcccttgct ttgatttttc
    84361 ttgttttggt tgatataaaa ttggctaccg ttagtattag cgccagcatt tgccatggca
    84421 agagcaccgc gaatatgata taaaaatgga gagatttcgt tgacaaagcc attgccagca
    84481 tcttttttag gatccttgcc cttccaaatc gattcaccac ctgtgccatc tcctttgggg
    84541 tcacctgatt gaatcataaa gtcgttgatc acacgatgga aggtaaggtt atcatagtag
    84601 ccttttttag catgggtgag gaagttctca acagctaagg gagcatattt tgggaataac
    84661 ttaagggtga tgtccccttg acttgtcctc attacgacct tagcttcttc tttgccgact
    84721 tctttggtta gttgtggaaa ttggctagca tcagctttga gagctttttg aatgctttct
    84781 tcataggctt tagaagctgc ttcgctttct tctttggcag ttttttcatc aatgtattta
    84841 tcgcctttta tagcgcggtc aacagattca caagcactca aactaagtaa actaatggct
    84901 actaaactga gagataataa ttttttcatg tctactccta agaatgattt tctttatttt
    84961 atcataaaat gcaacagaaa atagtagtaa agagttaaaa acgcctattt ttgtgtttta
    85021 tgatctaacc ttggttaaaa ggctgctacg actgttatta tagcacaaga tgctatagaa
    85081 aaacttaaaa caccttggtt ttttagagct atttcctaat agttaaaaaa tggtataata
    85141 gtgttatggt taaaagaaat caaagaagaa aaagtgcgcc taagaagtgt ctgacaaaag
    85201 cagaagtgga aaagcaacgt gccattaaga ggatgatttt atctgtttta atggctttgt
    85261 tgcttatttt tgcgatgctt cgcttgggcg tctttggcgt gacaacttat aatatgattc
    85321 gttttttggt gggtagttta gcctatccgt ttatgtttgc ctggttaatt tacttatttt
    85381 gttttaaatg gttacggcaa aaagatggaa tgattgcggg agttgttatt gcctttttgg
    85441 gattgctagt tgagtggcac gccttcttat ttgcgatgcc taggatgctt gatcaagata
    85501 tttttctagg cactgctcgg ctaattacaa gagatttact agccctgcgc gtgactgaat
    85561 ttgttggtgg aggaatgctt ggtgcattac tttataaacc catagccttt ttattttcga
    85621 atatcggctc ttactttatt ggttttttgt ttatcttatt aggattattt ctaatgacgc
    85681 cttgggatat ctatgatgtg agtcactttg tgaaagaggc tgttgataaa ctagcagtgg
    85741 cttatcagga aaataaagaa aagcggttca tcaaacgaga agagcaccgc ttacaagctg
    85801 aaaaagaggc tttagagaaa caagcacagg aggaagaaaa acgtctagca gaattgacgg
    85861 ttgatcctga gacgggagag attgttgagg atagtcagtc tcaagtcagc tatgatttgg
    85921 ctgaggatat gccaaaagag ccagagattc ttgcttatga tagtcacctc aaagacgatg
    85981 aggcaagctt atttgaccaa gaagacttgg cttacgctca tgaggaaatt ggggcttatg
    86041 actctttatc tgctttagca tcttctgaag atgagatgga tatggatgaa cctgttgatg
    86101 ttgatttcac gccaaaaacc catcttcttt ataaacttcc aacgatagat ttatttgcac
    86161 cagataagcc caaaaaccag tccaaagaga aaaacttagt ccgcaaaaat atcaaggtgc
    86221 ttgaagatac cttccaaagt tttgggattg atgtcaaggt agagcgagca gaaatcgggc
    86281 cttccgtcac caaatatgaa atcaagccag ctgtcggggt ccgagttaat cgtatttcaa
    86341 atcttgctga tgatttggca cttgctctgg ctgctaaaga tgttcgtata gaagcaccaa
    86401 ttcctggaaa atccttaata ggtattgaag ttcctaactc agaaattgca acggtttctt
    86461 tccgcgaact ttgggaacaa tctgatgcca atcctgaaaa ccttttagaa gtaccactag
    86521 gtaaagctgt taatggtaac gctcgcagtt ttaacttagc tagaatgccg catcttttgg
    86581 tagctggttc aactggttca ggtaaatcgg ttgctgttaa tggcattatt tcaagtattt
    86641 tgatgaaggc acgtccagac caagtgaaat ttttgatggt cgaccctaag atggttgagt
    86701 tgtctgttta taatgatatt ccccatttgc tgattccagt agtgaccaat cctcgtaaag
    86761 ccagcaaggc gttgcaaaaa gtggttgatg agatggaaaa tcgctatgaa ctctttagta
    86821 aagtcggggt tcgaaatatt gctggttaca atgcaaaagt tgaggattac aataggcaat
    86881 ctgagcaaaa acaaatgcct ttaccattga ttgtggttat tgtggatgag ttagctgatt
    86941 tgatgatggt ggctagtaaa gaagtggaag acgctattat ccgtctgggg caaaaggcgc
    87001 gtgcggcagg tattcacatg attcttgcaa cccaaagacc atctgtggat gttatttctg
    87061 gactgattaa ggccaatgtg ccatcccgta ttgcatttgc cgtatcttca ggaacagata
    87121 gtcgaacgat tctggatgaa aatggcgctg aaaagctctt aggacgtgga gatatgctct
    87181 ttaagccgat tgatgaaaat caccctgttc gtctgcaagg gtctttcatc tcagatgatg
    87241 atgtggagcg tattgtcaac tttatcaaag accaagctga agcggattat gatgatgcct
    87301 ttgatcctgg tgaagttagc gacaatgatc ctggtttttc tggaaatggc ggagctgctg
    87361 aaggtgatcc tctttttgaa gaagcaaaag ccttggtctt agaaacacaa aaagctagtg
    87421 cctcaatgat tcaaaggcgt ttgtcggttg gatttaatcg tgccacgcgc ttgatggatg
    87481 aattggaaga agcaggtgtt atcggtccag cagaaggaac caaacctcgt aaggtattgc
    87541 agacaaacta aaagaacctg acgtctcatg atgagatgtc aggttctttt tttgtgatgt
    87601 caagccagtt gatgagatgc ctatgctaat gtaaaaataa agataactag aatcaggtag
    87661 aaaataacgg tgactaaaaa gccaactcgc caaaatagct tcataaagcg atggtaagaa
    87721 aacgactgag ttcggatgac tagcagtagt gaaatgacga tggctagcag cgacatgata
    87781 ataaggtaat aaggcagtaa attatgggtg aaaaattttc ctgagacaag cacaatttct
    87841 atcgcaaaaa gtaaaagtgc gacatctgga aatttaaatc cctttttatt aagtttaaat
    87901 aaaggggtta caatcatggc aaaaagaggc gttactatca agaaagctaa ggcagttaat
    87961 ttatagatca tcataggtct attttatact caaatccctt acttgtaaac tgatacttac
    88021 ctgttgtgat agaaaatgat ctttgagagg gaaagcgcct acttcaattt aaacattaca
    88081 aaaggcatca gctattttaa caaaaagact tgatttattt tggcaataag ctataatggt
    88141 agggtatgca atattgcata tctgtgggag gtaaaaatct caattaccgc caaaaccaca
    88201 acaggaggat ttttaaaatg gctaaaaaag tcgaaaaact tgtaaaactt caaatccctg
    88261 ctggtaaagc tacaccagct ccaccagttg gaccagctct tggtcaagca ggtatcaaca
    88321 tcatgggctt cactaaagaa tttaacgctc gtacagctga tcaagctggt atgatcatcc
    88381 cagttgttat ctcagtttat gaagacaaat catttgattt catcactaaa acaccaccag
    88441 ctgctgttct tttgaaaaaa gctgcaggtg ttgaaaaagg atcaggtaca cctaacacta
    88501 ctaaggttgc gacagttact cgtgcacaag tacaagaaat tgctgaaact aagatgccag
    88561 atttgaacgc tgcaaacatt gaagctgcaa tgcgtatgat cgaaggtact gctcgttcta
    88621 tgggattcac tgttactgac tagtcagtca agaaccccta ttacccgcac gacttcatca
    88681 taagagatga gtgacgtggg agattttaaa tcaaatcgat atgaccacat tacaaggaga
    88741 attttaaaat ggctaaaaaa agcaaacaaa tgcgtgctgc acttgaaaaa gtagatagca
    88801 caaaagcgta cagtgtagaa gaagctgtag cattagtaaa agaaacgaac ttcgcaaaat
    88861 ttgatgcgtc tgttgaagtt gcttacaact tgaacattga cgttcgtaaa gcagaccaac
    88921 aaatccgtgg cgcaatggta ttgccaaacg gaactggtaa aacacaacgt gttcttgttt
    88981 ttgcacgtgg tgcaaaagct gaagaagcaa aagcagctgg tgcagacttc gtaggtgaag
    89041 acgaccttgt tgcaaaaatc aatggtggat ggcttgactt tgacgttgtt atcgcaacgc
    89101 cagacatgat ggctatcgta ggtcgtcttg gacgtgtcct tggacctcgt aacttgatgc
    89161 caaaccctaa aactggtaca gtaacgatgg atgttgctaa agccgttgaa gagtctaaag
    89221 gtggtaaaat cacttaccgt gctgacaaag caggtaacgt acaagctctt attggtaaag
    89281 tttcatttga tgctgacaaa ttggttgaaa acttcaaagc cttccacgat gtaatggcta
    89341 aagctaaacc tgcaacagct aaaggaactt acatggcaaa cgtctcaatc acatcaacac
    89401 aaggtgttgg tatcaaggtt gatcctaact cactttaaga aaaaaattag ggcatcgcct
    89461 aatcatagca aaaagacaaa tttctgaaga caaatcttca ctagaggttt gtctttttta
    89521 tggtttaaaa tggaatgcaa acaaaaaagt gtaggcgata ataccatgaa aggagttgat
    89581 tctcttaatg agatgtggtg ttaacacatc atgagctcac aaaaaatgat aaaggaagta
    89641 tcggtggtgt taaaaaaggg attttaattg acatttatta gcctctaaaa tgtcctttcc
    89701 ctattcataa ttgagggttt gtggtaaaat agtaaggaca aactaaggag aacatagtag
    89761 tggaacctaa atatcaacgt atattaatta agttatctgg tgaagcatta gcaggtgaaa
    89821 aaggagttgg cattgacatt ccaactgttc aggctattgc aaaagaaatt gccgaagttc
    89881 atgtgtcggg agtacagatc gctcttgtta ttggtggagg caatctctgg cgtggagagc
    89941 ctgcagcaga cgctggaatg gaccgtgttc aggctgatta cactggcatg cttggaacgg
    90001 tgatgaatgc cctagtcatg gctgatagtc ttcaacatta tggtgttgat acccgtgtgc
    90061 aaacagctat tcctatgcaa aatgtagcag aaccttatat tcgcggacgt gccttgcgcc
    90121 atctagaaaa aaatcggatt gttgtttttg gagctggtat tggctcgcct tatttttcaa
    90181 cagacaccac cgcggcactg cgtgctgctg agattgaagc agatgctatt ttaatggcaa
    90241 aaaatggtgt ggatggggtc tataatgctg atcctaaaaa agatgctaat gcggttaaat
    90301 ttgatgaatt aacacatggt gaagtgatca aacgtggtct caaaatcatg gatgcaacgg
    90361 catcgacctt atcgatggac aacgatattg atctggtggt tttcaatatg aatgaagctg
    90421 gcaatattca acgtgttgtc tttggagaac atattggaac tactgtatca aataaagttt
    90481 gtgactaaaa gttagaaaag aaagagagta attatcatgg caaatgcaat tattgaaact
    90541 gcaaaagaac gttttgcaca atcccatcag tctttatcac gtgaatatgc cagcattcgt
    90601 gcgggtcgtg ccaacgctag tcttttagac cgtatccaag ttgattatta cggggcaccg
    90661 acgccattaa atcaattggc ttcaatcact gtgccagaag cgcgtgtctt attgatctcg
    90721 ccttttgata aatcttctat caaagatatc gagcgcgctc ttaacgcatc agatttaggc
    90781 attacacctg ctaacgatgg ctctgtcatt cgtttggtta ttccagcttt gaccgaagaa
    90841 acacgtaaag aattagccaa agaagtgaaa aaagttggtg aaaatgctaa aattgcaatc
    90901 cgtaatatcc gccgtgatgc tatggatgat gctaaaaagc aagaaaaagc aaaagaaatc
    90961 actgaagatg agttaaaaac acttgagaaa gatatccaaa aagtaaccga tgatgctatc
    91021 aaagaaattg accgcatgac ggctgaaaaa gaaaaagaat tgctctcagt gtaacaggat
    91081 ttctacgaaa aatagacgac tatagacaca aaaagatagg tgaccatttc agaagcgttt
    91141 ggttttgatt tgtccctatt tttttaaaga aagaaaaaag atatgaatga tttactagca
    91201 acagtcatta ctgggcttat taaagaagaa aacgctaatg actattttat ccaaaaagag
    91261 gggtttacct ttaccttgtc taaagcagaa ggagaacgcc agattggtga tatggtcaca
    91321 ggctttgcct atacagacat aaagcaaaag gcacgtctca caaccaaaga gatccgttca
    91381 acacggacaa gttatggctg gggggaagtg acagaggttc gtcgtgacct aggcgttttt
    91441 gtcgatacag gaattccaaa taaagaaatt gtggtttctt tggacgtgtt gcctgaaatg
    91501 aaagaactat ggcctaaaaa aggggataaa ctttacattc gtttggatgt ggataaaaaa
    91561 gaccgtattt ggggacttcc agcagagcct gaggtctttc aaaagatggc tagccctgca
    91621 tacaataata tgcaaaatca acattggcca gcaattgttt accgcctaaa attaacagga
    91681 acgtttgttt acctgcctga aaacaacatg ttaggcttta ttcacccaag tgaacgctac
    91741 gcagaaccgc gcttaggtca ggttttagat gcccgtgtga ttgggtttag agaggtcgat
    91801 cgtaccctaa acttgtcgtt gaaaccacgt tcttttgaga tgttggagaa tgacgctcag
    91861 atgattgtca cttatcttga agccaatggt ggcttcatga ccttaaatga caaatcaagt
    91921 ccagaagaga ttaaagcaac ctttggtatt tcaaaaggcc agtttaaaaa agccttgggt
    91981 ggattgatga aagctaaacg catcaaacaa gacgccacag gaactgaatt aataggataa
    92041 aaatgctttg ccactggcaa agttttttgt tacaatgaag accattaagt gaagaaaaag
    92101 gggatataga gaatggaaag agccattttt gcaggaggtt gtttctggtg tatggtgcaa
    92161 ccttttgagg agcaagcagg tattttgtca gtcagaagtg gctacacagg tgggcatctc
    92221 ccaaatccta gctatgaaca agtttgtgcc aaaacaacag gacatacaga agctgttgaa
    92281 attatttttg accctgaaga gatcagctat aaggaattag ttgaattgta ttgggtgcag
    92341 acggatccaa cagacgcctt tgggcaattt gaagatcgtg gggacaacta ccgtcctgtc
    92401 atttactaca caacagaaag acaaaaagaa attgcagagc aatcaaaagc aaacttgcaa
    92461 gcttcaggac gttttgacca acccattgtc accactattg aaccagcaga gccattttat
    92521 ctcgcagagg attatcacca aggattttat aaaaagaatc ccaggcggta tgcacaaagc
    92581 agtgctattc gtcatcagtt tttagaggag aattggtcat gagaaaatca ttttacagct
    92641 ggctgatgac acaacgtaac cctaaatcaa atgcacctgt ggcgatttta gcagatttgg
    92701 tgtttgatga caccactttt ccaaagcata ccaatgattt tgaactcatt agtcggtatc
    92761 tagaagatca agctagtttt tcctttaatt taggtcaatt tgatgaaatc tgggaagatt
    92821 atctagcaca ttaatacgtg gataagaaag agtcatatcg actcttttga agggttatca
    92881 cgttattatt acaaaatgac atcactttct ttcaaaaaaa tgacaagcta ctttttttct
    92941 taaaaatatg ctatgatata gcttagaaaa aaataaaaag gaagcagaga tgattattac
    93001 taaaaagagt ttatttgtga caagtgtcgc tttgtcgtta gcacctttgg cgacagcgca
    93061 ggcacaagag tggacaccac gatcggttac acaaatcaag tctgaactcg tcctagttga
    93121 taatgttttt acttatacag taaaatacgg tgacacttta agcacaattg ctgaagcaat
    93181 ggggattgat gtgcatgtct taggagatat taatcatatt gctaatattg acttaatttt
    93241 tccagacacg atcctaacag caaactacaa ccaacacggt caggcaacga ctttgacggt
    93301 tcaagcgcct gcttctagtc cagctagcgt tagtcatgta cctagcagtg agccattacc
    93361 ccaagcatct gccacctctc aatcgactat tcctatggca ccatctgcga caccatctga
    93421 tgtcccaacg acaccattag catctgcaaa gccagatagt tttgtgacag cgtcatctga
    93481 gctcacatca tcaacgaatg atgtttcgac tgagttgtct agcgaatcac aaaagcagcc
    93541 agaagtacca caagaagcag ttccaactcc taaagcagct gaaacgactg aagtcgaacc
    93601 taagacagac atctcagaag attcaacttc agctaatagg cctgtaccta acgagagtgc
    93661 ttcagaagaa gcttcttctg cggccccagc acaagctcca gcagaaaaag aagaaacctc
    93721 tcagatgtta actgcgccag cagcacaaaa agctgtagct gacaccacaa gtgttgcaac
    93781 ctcaaacggc ctttcttacg ctccaaacca tgcctacaat ccaatgaatg cagggcttca
    93841 accacaaaca gcagccttca aagaagaagt ggcttctgcc tttggtatta cgtcatttag
    93901 tggttaccgt ccaggagatc caggagatca tggtaaagga ttagccattg actttatggt
    93961 accggttagc tctacgcttg gtgatcaagt tgctcaatat gccattgacc atatggcaga
    94021 gcgtggtatt tcatacgtta tttggaaaca gcgattctat gcgccatttg caagtattta
    94081 cggaccagcc tacacatgga accccatgcc agatcgcggc agtattacag aaaaccatta
    94141 tgatcatgtt catgtctcct ttaatgctta attcatgcta tcaaaaaaac tcacgtttag
    94201 gcgtgagttt tttgacaatt ctgacagagt aagccctata agaggctgag atacgctttt
    94261 aatacctgtt gtttttctcg ccctttagac agttttaacg ttatgtctaa aagagatggt
    94321 ttttattagc gcaaatatgg gtttaggggt aaaatataga taattaacct gatatgatca
    94381 tgataaaggt agaagaatac ctattatttc gtgacaactg agcaatctgc ccttaccttt
    94441 ggagtgatga tatcactttg cttgactatt caaggaggtc ttgaaatgta ttatactagt
    94501 ggtaattacg aagcttttgc gacacctcga aaacctgaag gggtagatca gaaatcggct
    94561 tatattgttg gtactggttt agctggttta gcagcagctg ttttccttat tcgcgatggg
    94621 catatggctg gggaacgcat tcatctgttt gaggaattgc ctttagcagg tggttcttta
    94681 gatggtattg aaaagcctca tcttggtttt gtgacccgtg gtggtcgtga gatggaaaat
    94741 cattttgagt gtatgtggga catgtatcgg tctattccct cactggaaat tcctggtgcg
    94801 tcttatttgg atgaatttta ttggttggat aaggatgatc ctaactcatc caactgtcgt
    94861 ttgattcaca agagaggaaa tcgtgtggat gatgacggcc agtatacgct cggtaaacag
    94921 tcaaaagaat tagtccattt aatcatgaag acagaagaat ctctaggaga tcaaaccatt
    94981 gaagagttct tctcagaaga tttctttaag agtaattttt ggatctattg ggcaaccatg
    95041 tttgcttttg aaaaatggca ttctgctgta gaaatgcggc gctatgcgat gaggtttatc
    95101 caccatattg atggtttgcc agatttcacc tctctcaagt tcaacaaata taaccaatat
    95161 gattctatgg tcaaaccgat tattgcttac ctagaatcac acgacgttga catccaattt
    95221 gacacaaaag tcactgatat tcaggtggaa caaacagctg gtaaaaaggt agcaaaaacc
    95281 atccatatga cggtgtctgg ggaggctaag gcgattgagc taacacctga tgatttggtt
    95341 tttgtgacca atggttctat tactgaaagt agcacatacg gtagtcatca cgaagtggct
    95401 aagccaacca aagcgttagg tggttcttgg aatttatggg aaaatctagc tgctcaatca
    95461 gatgattttg gtcatcctaa agtgttttac caggacttgc ctgctgaaag ctggtttgtg
    95521 tctgccacag caaccataaa acacccagct atcgagcctt atattgaacg tttgacccac
    95581 cgtgatttgc acgatggcaa agtgaacact ggcggcatca tcactattac agattctaac
    95641 tggatgatga gctttgccat tcaccgtcaa cctcatttta aagaacaaaa agataatgaa
    95701 accactgtct ggatttacgg tctttattcc aatagtgagg gcaattacgt ccacaagaaa
    95761 attgaggagt gtacaggtca agaaatcaca gaagaatggt tgtaccacct tggggtacct
    95821 gttgataaaa tcaaggactt agcgagtcag gactatatca atacagttcc tgtttacatg
    95881 ccttatatta cgagttactt tatgccacgt gtcaaaggag accgtccgaa agttatccca
    95941 gatggttcag tcaacttggc ctttattggt aactttgcgg aatctccatc tcgagatacg
    96001 gtctttacga ctgagtattc tattcgtact gccatggaag cagtgtatag cttcttgaat
    96061 gtggaacgag gcattccaga agtctttaat tcagcctatg atattcgtga attgctcaaa
    96121 gccttttatt accttaatga taaaaaggca atcaaggata tggatttgcc aattcctgca
    96181 ctgattgaga aaatcggaca taaaaaaatc aaggatacct ttatcgaaga attgctcaaa
    96241 gatgctaatc ttatgtaaca tgccttagag tagttaaagc tgataagttt aggcttatca
    96301 gcttttttga tgatttatag aaaagtgata aaggaaaagt ctgacgtgaa cgtcacataa
    96361 gaatttaaaa tttgttataa tgtaagcaat aaagatgaaa gaaagaggga ctctatttgc
    96421 aagagtattc tattgacatt accttaaccc atcctgatga tgttttagct ctttttggta
    96481 gcaacgagcg tcatttgaag ctaatagaag ctcatttagg agttattgtt cacgcaagaa
    96541 ccgagcgagt ccaagtgatt ggtgatgatg aagaagctgt ggaattggct cgattgacca
    96601 tcaaagccct actggttcta gtgggtcgtg gcatggtggt caacacatca gatgtggtga
    96661 cagctttatc tatggcagaa tctcatcaga ttgaccaatt tatggcgctt tatgaagaag
    96721 aaatcattaa agataactat ggtaaggcaa tacgagtcaa aacattaggt caaaaaacct
    96781 atgttgatag tgtcaaacgt catgatgtgg tttttggtgt aggacctgca gggacaggga
    96841 aaaccttctt agctgttacg cttgcagtca ctgctctgaa aagaggacag gtaaagcgta
    96901 ttattttgac gcgtcctgcg gtagaagctg gtgaaagcct aggtttttta ccaggcgatt
    96961 tgaaagaaaa ggtggatcct tacctcagac ctgtttacga tgccctttat cacattttag
    97021 gcaaggaaca aaccacacgc ctgatggaac gagatgtgat tgagattgct ccgttagctt
    97081 atatgcgggg tcgtactctg gatgacgctt ttgttatctt agatgaggct caaaacacga
    97141 ccatcatgca aatgaagatg tttttgaccc gtcttggttt taattctaaa atgattgtca
    97201 atggagatac gagtcagatt gacctccctc gaaatgtcaa gtctggtttg attgatgcta
    97261 ctcagaaatt acaaggcatt aaacagattg attttgtcta tttctctgct aaggatgttg
    97321 tccgacatcc tgttgtggct gatattatca aggcttatga aacgtcctca gaggagatga
    97381 aggacttact aaaacctaag gctagtgacg ttgaagctga ttaccagcca ggcttgacaa
    97441 aataccctgt gattggtcaa gagcactaag atttttacga tgatgtttaa tatggccttt
    97501 ttaaggagga ttctatggat gatttaacca aagctattat ggcagatgag gctaatctct
    97561 cctataccga aagaggtatt tttcctttat atgatgctcc tcaaacagct aggcttatta
    97621 ttgttggcca agctcctgga atagtagctc aagaaaccaa actttactgg aatgatcgta
    97681 gtggcatccg cttacgagac tggctaggtg tggacaatga caccttttac cactcaggat
    97741 tgtttggcat tatccctatg gatttctatt atcctggtaa gggaaaatcc ggtgacttac
    97801 cacctagaga aggttttgcg gctaagtggc acccgccatt aagagcattg atgccagaag
    97861 ttgaattgac gattttggtt ggtcgctatg ctcaggactt ttaccttggt aacaaggctt
    97921 acaaaacctt aactgaaaca gtccgtcact ttgaggatta cttgccagac tattttccac
    97981 ttgttcatcc ttctccaaga aaccaattgt ggttagctaa gaacccctgg tttgagcagg
    98041 atttattacc tatcttgcaa aaacgtgtgg aggcaattct aaccaaatag gccctgattt
    98101 acctagcatt cccatttttt aggggcttgt ggtataatgg gtaaataaca aatgctgatt
    98161 gaaaggataa gggaaattat ctgtcagata ataatgggtg cccaacatac caaatgaggt
    98221 gggcagccct tccctaacaa ttaaccttat gtatatcgag atgattgacg aaacgggaca
    98281 agtttcgcaa gagattatgg agcaaacact tgatttgctc aattttgctg ctcaaaagac
    98341 gggcaaagaa gaaaaagaaa tgtctgtgac ctttgtgacc aatgaaagaa gtcatgaact
    98401 caacttagaa taccgagata ctgatcgtcc aacagatgtg atttctctag aatataagcc
    98461 agaaacgcct attttattta gtcaagagga ttttgctgct gatcctagtt tggcagagat
    98521 gatggcagag tttgatgctt atattggcga attgtttatt tctattgaca aggcgcgtga
    98581 gcagtcccaa gaatatgggc actcttttga gcgtgaaatg ggatttttag ctgttcatgg
    98641 attcttacat attaatgggt atgatcacta cacccttgaa gaagaaaaag agatgtttac
    98701 cttacaggaa gagattttga ctgcttatgg ccttacacga caataatacc accaaacgga
    98761 aatggaaaaa cagaaccatt acctcaagcc tggagtttgc cttgacaggg gttttcacag
    98821 cttttaagga agaacgcaat ctcagaagtc accttttgtc tgcctgttta gcttgtgttg
    98881 ctggtttatt ttttagcatt tcagccatcg aatggttatt tttacttcta gccatttttt
    98941 tggtcattac cttagaaatt gtcaattctg ctattgaaaa tgtagttgat ttggctagtg
    99001 actatcactt ttctatgcta gctaaaaatg ccaaggatat ggcagcaggt gctgttttga
    99061 tgatttctgg ctatgctgtc ttgacaggac ttattatttt tattcctaaa atttggaata
    99121 ttttcgttca ttaaaaagaa aggaatgggc tatcctatgt gatgatggca taggagaata
    99181 aggaaaggac aagacggtta agcttagtga caagcttgat ctgaagccct accgttaagg
    99241 cccgtaatta tctatgttta aatcaggctt tgtagccatt cttggtcgtc caaatgttgg
    99301 caaatccacc tttttaaatc acgtcatggg gcaaaaaatt gccatcatga gtgacaaggc
    99361 tcagaccacc cgtaataaaa ttatgggcat ttacaccaca gaaacagaac aaattgtctt
    99421 tattgatacg ccaggtattc ataaaccaaa gaccgccctt ggtgatttta tggttgaatc
    99481 tgcttatagt actttacgtg aagttgagac ggttcttttc atggttcctg ccgatgaaaa
    99541 gcgtggtaag ggtgacgaca tgattatcga gcggctaaaa gcagctaaga ttcctgttat
    99601 tttagttatc aacaaaattg ataaggttca tccagaccaa cttttggaac agattgatga
    99661 cttccgtagc caaatggatt ttaaagaagt ggtcccaatt tctgccctag aaggtaataa
    99721 tgtgccaacc ctaatcaagt tattaactga taatcttgaa gaaggtttcc aatattttcc
    99781 agaagatcag attactgatc atccagaacg tttccttgtg tcagaaatgg ttcgtgagaa
    99841 ggtactgcat ttgacgcaac aagaggttcc acattccgta gctgttgttg tcgaatccat
    99901 gaagcgagat gaagagactg ataaagtgca tatccgtgca accattatgg tggagcgcga
    99961 tagccaaaaa ggcatcatca ttggaaaaca aggagccatg ctcaaaaaaa tcggaaaaat
   100021 ggcgcgccgt gatattgaac tcatgttagg tgacaaggtc tacttagaaa cgtgggtcaa
   100081 agtcaagaaa aactggcggg ataaaaagct tgatttagct gattttggct ataatgagaa
   100141 agaatactaa catagtaaag cgagatcata tgccacaaga ctacatttct tatatccgct
   100201 ccaaagttgg gcatgataag attattctta actttgctgg tgggattttg accaatgatg
   100261 acggcaaggt gctgatgcag ttgcgtggtg ataagaaaac ctgggctatt cctggtggta
   100321 ctatggaact gggtgagagc tctttagaga cttgcaaacg tgagttctta gaggaaaccg
   100381 gaattgaggt tgaagctgtt cgcttactga atgtttacac tcattttgag gaagtttatc
   100441 ccaacggtga tgctgttcag actattgtct ttatctatga actaacggct gtttctgata
   100501 tggctattga taactttcat aatgaggaaa cgctcaagtt acagtttttc tctcatgagg
   100561 agatagcaga gttagagagt gtctcagcca aacatcgcct gatgttagag gaatatttta
   100621 gtgatagctt tgctatgggg cattaagaac tctctaggac agttggagta tttttggaga
   100681 ttggcttgtt aaaaaaattt ttgaaagacg atgtttcgag agcttatgct ctcttttttt
   100741 gcttccaatt tttctgatta agtctgaata attttgttaa atgttaacag gattttcttt
   100801 ccaattgata ctagcagaca tcaaacattt gttttagagt tatgacgaat tgccacctag
   100861 ccatgcatga cttaggcaag ttgaacctaa ctgtggcaat agacttggaa ggggtgacaa
   100921 gaatcatttc ctaaaagaat tgatgaagtg cctatccatt attcgaattg taaagttcgt
   100981 ctaagtaaag ttgaatttga tctcgaatgg actttaatga tttatgactt gttgtgtcaa
   101041 taacaccaaa aactcgataa tgatttttaa atatttcctc gtaattaata tgatttccga
   101101 ttagaataat atgagcatga ggataacgca tacgtatttc gtttagaagg tcatatactt
   101161 gctcagattt aaaaaagt
//
LOCUS       DATWEK010000003        93726 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.003, whole genome shotgun sequence.
ACCESSION   DATWEK010000003 DATWEK010000000
VERSION     DATWEK010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 93726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 93726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..93726
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.003"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            115..1350
                     /gene="arcA"
                     /locus_tag="VCR92_000242"
     CDS             115..1350
                     /gene="arcA"
                     /locus_tag="VCR92_000242"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEP4267341.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            1450..1878
                     /locus_tag="VCR92_000243"
     CDS             1450..1878
                     /locus_tag="VCR92_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP4267342.1"
                     /translation="MTDKFDANDETRTVYAVVYDNDQPVSTGQFLAETKIEARLTRIV
                     TLADYCGCGYGAKVTEALETYTRREGFYQLTIHSELTAQTFYENLGYQSYGPKCLEDG
                     EYCQSLAKTILKWEKNMDIAMLIAIVGGLLGCYLYLTKNN"
     gene            1918..2931
                     /gene="argF"
                     /locus_tag="VCR92_000244"
     CDS             1918..2931
                     /gene="argF"
                     /locus_tag="VCR92_000244"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEP4267343.1"
                     /translation="MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEIVTLAEGYAKESGARILITEDA
                     DEAVKGADVLYTDVWVSMGEEDKFKERVELLQPYQVNMNLVQKAGNDKLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVKEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            3101..4594
                     /locus_tag="VCR92_000245"
     CDS             3101..4594
                     /locus_tag="VCR92_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEP4267344.1"
                     /translation="MTEEKKRGFRIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKGGG
                     VISGTYKTVASNPQGFFDILMAPVRGMLGVEGTDGAIQVSFFILMVGGFLGVVNKTGA
                     LDTGIASVVRKNKGREKMLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRVIQWVILVGMSIWFV
                     YNYASKIEEDPSKSLVADKEEEHKELFQLQNSGEDLNKRQRNVLTIFTLTFVIMILSL
                     IPWEDFGIKFFTNINTWLTTMPILGGVIGKTMGAFGTWYFPEITMLFIMMGVLVAIVY
                     RMSEEDFFSSFLTGAGEFLGVAMICAIARGIQVIMNGGMITATILHLGETSLSGLSSQ
                     VFVILAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRVDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            4611..5942
                     /locus_tag="VCR92_000246"
     CDS             4611..5942
                     /locus_tag="VCR92_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEP4267345.1"
                     /translation="MESYITPKHQEACVAAIKQIVSYPSVCHEGENGTPFGQAIQDVL
                     EATLDLCQGLGFHTYIDPEGYYGYAELGDQKEVLAILCHLDVVPEGDRQLWKTDPFDC
                     VEADGCLFGRGTQDDKGPTMMALFATKALIDAGVTFNKRIRFIFGTDEETLWRCMNRY
                     NDVEEQATFGFAPDSSFPLTYAEKGLLQAKLVGKGSDKLSLEIGQAYNVVPARASYKG
                     NKLEALQKELDKLGFEYVVKEGELTVYGLAQHTKDAPDGINAMIRLAKALVVLEPNKT
                     LDFLANVIDEDGRALNIFGRIEDEPSGKLSFNAAGLTLTKDKAEIRLDIRIPVLADKE
                     KLVQQLSQKAQEYGLTYEEFDYLAPLYVPLDSELVTTLLSVYRKKTGDQSPAQSSGGA
                     TFARTMKNCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            5962..6912
                     /gene="arcC"
                     /locus_tag="VCR92_000247"
     CDS             5962..6912
                     /gene="arcC"
                     /locus_tag="VCR92_000247"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEP4267346.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALISTSKSLVKLIKEGH
                     EVIVTHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GIQKEVAAVVTQVIVDAKDPAFENPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPVGIKEANVIRSLVDSGVVVVSAGGGGVPVVEDATSKSLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYINFNKPDQAKLEEVTVSQMKEYITQDQFAPGSMLP
                     KVEAAIAFVENKPNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            7225..8217
                     /locus_tag="VCR92_000248"
     CDS             7225..8217
                     /locus_tag="VCR92_000248"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEP4267347.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGTENPVSVNVLKIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGKRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVAKYPDLTPKERENAITKEFGAVFLIGIGGVLPDGKPHDGRAPDY
                     DDWTTETENGYHGLNGDILVWNDQLGSAFELSSMGIRVDEEALKRQVEMTGDQDRLAF
                     DWHKSLLNGLFPLTIGGGIGQSRMVMFLLRKKHIGEVQTSVWPQEVRDSYDNIL"
     gene            8340..8879
                     /gene="rsmD"
                     /locus_tag="VCR92_000249"
     CDS             8340..8879
                     /gene="rsmD"
                     /locus_tag="VCR92_000249"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEP4267348.1"
                     /translation="MRVVSGEFGGRPLKTLDGKITRPTSDKVRGAIFNMIGPYFNGGR
                     VLDLFAGSGGLAIEAVSRGMSAAVLVEKNRKAQAIIQDNIIMTKAENRFTLLKMEAER
                     AIDCLTGRFDLVFLDPPYAKETIVATIEALAAKNLLSEQVMVVCETDKTVLLPKEIAT
                     LGIWKEKIYGISKVTVYVN"
     gene            8869..9360
                     /gene="coaD"
                     /locus_tag="VCR92_000250"
     CDS             8869..9360
                     /gene="coaD"
                     /locus_tag="VCR92_000250"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEP4267349.1"
                     /translation="MLTKIGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKK
                     SYFKLEVRKAMLTQALADFTNVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEYEE
                     NLEYFNHLLAPNIETVYLISRNKWQALSSSRVRELIHFQSSLEGLVPQSVIAQVEKMN
                     EKT"
     gene            9347..10384
                     /locus_tag="VCR92_000251"
     CDS             9347..10384
                     /locus_tag="VCR92_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEP4267350.1"
                     /translation="MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTV
                     LQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTPFTEISTAEDTTGGYSDTDFLRI
                     NQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
                     QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSV
                     NSEDTVIFSTKGVGGPSAGLMFTLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGG
                     AGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRAAKRLKTKMKIVPVT
                     TVQEALVYLRK"
     gene            10799..11776
                     /locus_tag="VCR92_000252"
     CDS             10799..11776
                     /locus_tag="VCR92_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP4267351.1"
                     /translation="MVTIKQVAEEAGVSRSTVSRYISQKGYVSDDARHKIKAAIAKLH
                     YTPNVLAQSLKTKKNQLVGLLLPDISNPFFPRLARGAEEYLKEKGYRVMLGNISDSEA
                     LEEEYVHVLLQSNAAGIITTHDFTKRYPTLAIPVVVVDCVDQETQYGVFSDNRAGGLL
                     AAQTVWQAGAKEVLLIRGPLDNAENINERFEASFSYLQKQDVTMYVCDSQNFDFESIQ
                     LEASYNLKCYPTIDSIIAPSDIHAIAYIHELHSQGKKIPQDVQIIGYDDILMSQFIYP
                     SLSTIHQSSYLMGRYAAELVYTIASQLTVKANRIKLPVHYVERETIRKR"
     gene            12200..12844
                     /locus_tag="VCR92_000253"
     CDS             12200..12844
                     /locus_tag="VCR92_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1027 domain-containing protein"
                     /protein_id="HEP4267352.1"
                     /translation="MDFSERCQMKKEISPEMYNYNKFPGPKFIHFEEQVKAEGIDLLL
                     LEDVKNAFDTTSFGQRYTEVLLKYDYIVGDWGNEQLRLKGFYKDSDDIKKTNRISRLE
                     DYIKEFCNFGCAYFVLENLHPQDIKFEEERQPRRKKSPKSKSNRRKPNYSNQQPATPK
                     SKSKRVSKEKQPENQAFTSQKRRSNTKHKEKSKRNQTSQLNTKISHFIIRKKDK"
     gene            12848..13927
                     /gene="rlmN"
                     /locus_tag="VCR92_000254"
     CDS             12848..13927
                     /gene="rlmN"
                     /locus_tag="VCR92_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEP4267353.1"
                     /translation="MKPSIYSLTRDELIAWAVERGQKQFRATQIWDWLYKKRVQSFEE
                     MTNISKDFVSILNDSFCVNPLKQRVVQESADGTVKYLFELPDGMLIETVLMRQHYGHS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMLVQKYFDDRKQGERVSHVVVM
                     GIGEPFDNYKNVMCFLRVINDDNGLAIGARHITVSTSGLAHKIRDFANEGVQVNLAVS
                     LHAPNNDLRSSIMRVNRSFPLEKLFSAIEYYIEKTNRRVTFEYIMLNEVNDSIKQAQE
                     LADLTKTIRKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDVLKKNGVNCVVRQEHGT
                     DIDAACGQLRSKTMKKDREKVTATK"
     gene            complement(14009..14635)
                     /locus_tag="VCR92_000255"
     CDS             complement(14009..14635)
                     /locus_tag="VCR92_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEP4267354.1"
                     /translation="MIAFFSICSGILLTHLFYCLLLYFPDNGQEQLSKQTVIVCDQLT
                     FAKRVFRQLQNHFITSQKIFFSLEISLIIILWASMVHWVSASYCYLLLFSLLFSLFDW
                     RSQEYPFILWLFSFVSLLLFYSINYLSLILLLLGLLAHLRPFSIGAGDFFYLASLALV
                     LDLTSLIWLIQLASLAGITACLLLGIKRIPFIPYLSFGLFWIVLLEHF"
     gene            14863..15390
                     /locus_tag="VCR92_000256"
     CDS             14863..15390
                     /locus_tag="VCR92_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012997888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEP4267355.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDSLNANLDEMSERLITIGGAPYSTLAEFSKHSK
                     LDEAKGTYDKTVAQHLARLVEVYLYLSSLYQVGLDITDEEGDAGTNDLFTAAKTEAEK
                     TIWMLQAERGQGPAL"
     gene            15532..15735
                     /locus_tag="VCR92_000257"
     CDS             15532..15735
                     /locus_tag="VCR92_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEP4267356.1"
                     /translation="MKTLYDVQQLLKNFGIFVYLGKRLYDIEMMKIELQRLYDSGLLD
                     KRDYLNAELILRREHRLELEKEG"
     gene            15740..16711
                     /locus_tag="VCR92_000258"
     CDS             15740..16711
                     /locus_tag="VCR92_000258"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEP4267357.1"
                     /translation="MSQKLLGIDLGGTTIKFGILTAAGEVQEKWAIETNILEGGKHIV
                     PDIIASIKHRLDLYGLSSADFVGIGMGSPGAVDRDTNTVTGAFNLNWKETQEVGSVVE
                     KELGIPFAIDNDANVAALGERWVGAGENNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPENGFACTCGSHGCLETVASATGVVKVARLLAEAYEGDSAIKAAIDNG
                     EGVTSKDIFMAAEAGDSFADSVVEKVGYYLGLASANISNILNPDSVVIGGGVSAAGEF
                     LRSRIEKYFVTFTFPQVRYSTKIKIAELGNDAGIIGAASLARQFITK"
     gene            16721..17110
                     /locus_tag="VCR92_000259"
     CDS             16721..17110
                     /locus_tag="VCR92_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEP4267358.1"
                     /translation="MSPITLILWLLLVGIVGYYTWNYFSFRKMAKQVDNETFKDVMRQ
                     GQLIDLREPAAFRAKHILGARNFPAQQFDAAIKGLRKDKPVLIYENMRPQYRVPAVKK
                     LKKAGFEDVYVLKDGIDYWDGKVKQTT"
     gene            17293..19134
                     /gene="typA"
                     /locus_tag="VCR92_000260"
     CDS             17293..19134
                     /gene="typA"
                     /locus_tag="VCR92_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEP4267359.1"
                     /translation="MTNLRNDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLIPIVVVNKIDKPSARPAEVVDEVLELFIELGADDEQ
                     LEFPVVYASAINGTSSLSDDPADQEHTMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPILRIDEPTLQMTFLVNNSPFAGREGKWITSR
                     KVEERLLAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVQGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            19256..19507
                     /locus_tag="VCR92_000261"
     CDS             19256..19507
                     /locus_tag="VCR92_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEP4267360.1"
                     /translation="MFYLIMAVSIISYYLYMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPPEFFIGMGMVALGYFALKDVRKMTKKPRVK"
     gene            19863..21221
                     /locus_tag="VCR92_000262"
     CDS             19863..21221
                     /locus_tag="VCR92_000262"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEP4267361.1"
                     /translation="MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFD
                     QNPAAQALLEEGIKVICGSHPVELLDEDFEYMVKNPGIPYDNPMVKRALAKEIPILTE
                     VELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIA
                     GDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESD
                     YLILNANQEISATLAKTTKATVIPFSTQKVVDGAYLKDGILYFKEQAIIAATDLGVPG
                     SHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNI
                     LATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKA
                     EVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRG
                     DA"
     gene            21221..22303
                     /locus_tag="VCR92_000263"
     CDS             21221..22303
                     /locus_tag="VCR92_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEP4267362.1"
                     /translation="MPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEH
                     TEIEKSGLDVTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFSKG
                     GFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQLSKVKHLG
                     AVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRY
                     NIINITGDPHLNELSSHLYRVDYVTDLYQPLMAMADLVVTRGGSNTLFELLAMAKLHL
                     IVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATML
                     ATKEIQSPDFFYDLLRADISSAIKEK"
     gene            22304..23452
                     /locus_tag="VCR92_000264"
     CDS             22304..23452
                     /locus_tag="VCR92_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HEP4267363.1"
                     /translation="MAKDKEKQSDDKLVLTEWQKRNIEFLKKKKQQAEEEKKLKEKLL
                     SDKKAQQQAQNASEAVELKTDEKTDSQEIESETTSKPKKPKKVRQPKEKSATQIAFQK
                     SLPVLLGALLLMAVSIFMITPYSKKKEFSVRGNHQTNLDELIKASKVKASDYWLTLLT
                     SPGQYERPILRTIPWVKSVHLSYQFPNHFLFNVIEFEIIAYAQVENGFQPILENGKRV
                     DKVRASELPKSFLILNLKDEKAIQQLVKQLTTLPKKLVKNIKSVSLANSKTTADLLLI
                     EMYDGNVVRVPQSQLTLKLPYYQKLKKNLENDSIVDMEVGIYTTTQEIENQPEVPLTP
                     EQNAADKEGDKPGEHQEQTDNDSETPANQSSPQQAPPSPETVLEQAHG"
     gene            23664..25028
                     /gene="ftsA"
                     /locus_tag="VCR92_000265"
     CDS             23664..25028
                     /gene="ftsA"
                     /locus_tag="VCR92_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEP4267364.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAATAIKTAVEQAEEKAGMTIEKVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKTILNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSLAIAEALKFNFGQAEISEASITETVKVD
                     VVGSEEPVEVTERYLSEIISARIRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEIAQEIFGVTVKLHVPNQVGIRNPMFSNVISLVEYVGMMSEVDVLAQTAVSGEELLR
                     RKPIDFSGQESYLPDYDDSRRPESTIGYEQQASQTAYDSQVPSDPKQKISERVRGIFG
                     SMFD"
     gene            25052..26371
                     /gene="ftsZ"
                     /locus_tag="VCR92_000266"
     CDS             25052..26371
                     /gene="ftsZ"
                     /locus_tag="VCR92_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEP4267365.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEEILTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRGNFAIEGIEELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAQDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDTMKDDIRVTVVATGVRQEKAEQVSGFRQPRTFT
                     QTNAQQVAGAQYASDQAKQSVQPGFDRRSNFDFDMGESREIPSAQKVISNHNQNQGSA
                     FGNWDLRRDNISRPTEGELDNHLNMSTFSANDDSDDELETPPFFKNR"
     gene            26374..27045
                     /locus_tag="VCR92_000267"
     CDS             26374..27045
                     /locus_tag="VCR92_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEP4267366.1"
                     /translation="MDLLTNKKKIFETIRLSTEAANRTNDSVSVIAVTKYVDSTIAGQ
                     LIEAGIEHIAENRVDKFLEKYDALKYMPVKWHLIGTLQRRKVKEVINYVDYFHALDSV
                     RLALEINKRADHPVKCFLQVNISKEESKHGFNISEIDEAIEEIGKMEKIQLVGLMTMA
                     PANASKESIITIFRQANQLRKNLQLKKRKNMPFTELSMGMSNDYPIAIQEGSTFIRIG
                     RAFFH"
     gene            27057..27713
                     /locus_tag="VCR92_000268"
     CDS             27057..27713
                     /locus_tag="VCR92_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEP4267367.1"
                     /translation="MAFKDTFNKMISYFDTDEVNEVEEDVAASTDNVIPRSQQSVRAS
                     SHPKQEPRNNHVQQDHQARSQEQTRSQMHPKHGTSERYYQQSQPKEGHEMVDRRKRMS
                     TSGIANRREQYQQSTCSDQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQFMLDAQA
                     RRCLDFIDGASKVLYGSLQKVGSSMYLLAPSNVSVNIEEMTIPHTTQDIGFDFDMKRR
                     "
     gene            27718..27972
                     /locus_tag="VCR92_000269"
     CDS             27718..27972
                     /locus_tag="VCR92_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEP4267368.1"
                     /translation="MILILSILLRLIKVYTYLLIAYALMSWFPGAYDSKIGRLISGIV
                     EPILKPFRAFNLQFAGLDFTIFVVIISLNFLAQVLVRVFI"
     gene            27972..28763
                     /locus_tag="VCR92_000270"
     CDS             27972..28763
                     /locus_tag="VCR92_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEP4267369.1"
                     /translation="MVSHSKIYQHFHQEEYPFIDRMSDMINRVGDYYLLEVTEFLNPR
                     EVMILKSLIALTDLKMFVSTDYYPSEYGRVIIAPGYYDLEQSDFQIALVEISYQAKFN
                     QLTHSQILGTLINELGVKRNLFGDVFVEMGYAQLMIKRELLDYFLGTITKIAKTSVKL
                     REVNFDQLIRSIDNSQTLDILVSSFRLDGVVATILKKSRTQVIALIEANKIKVNYRLA
                     NKASDNLVIGDMVSIRGHGRFTLLADNGVTKHGKQKITLSKMIHK"
     gene            28773..29531
                     /locus_tag="VCR92_000271"
     CDS             28773..29531
                     /locus_tag="VCR92_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEP4267370.1"
                     /translation="MALTTLEIKDKTFKTKFRGYCEEEVNEFLDIVVDDYEALVRKNR
                     DNEARIKDLEEKLSYFDEMKESLSQSVILAQETAEKVKATANAEATNLVSKATYDAQH
                     LLDESKAKANQMLRDATDEAKRVAIETEELKRQTRVFHQRLISSIESQLSLSNSPEWD
                     ELLQPTAIYLQNSDDAFKEVVKTVLNEDIPESDDSASFDATRQFTPEELEELQRRVDE
                     SNKELEAYQLDSQSDSTTEPEVNLSETQTFKLNI"
     gene            29804..32605
                     /locus_tag="VCR92_000272"
     CDS             29804..32605
                     /locus_tag="VCR92_000272"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEP4267371.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQAAWEQAELYKKRQELN
                     AGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRSKSMSGFQAPYVPGWDTHGLPIE
                     QVLAKQGIKRKEMDLAEYLEMCRQYALSQVDKQRDDFKRLGVSADWENPYVTLDPQFE
                     ADQIRVFGAMAEKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANKVKDGK
                     GILDTNTYIVVWTTTPFTVTASRGLTVGPDMDYLVVKPAGSDRQYVVAEGLLDSLAGK
                     FGWESFETLASHKGADLEYIVTEHPWDTDVEELVILGDHVTLESGTGIVHTAPGFGED
                     DYNVGTKYKLEVAVTVDERGLMTENAGPDFHGQFYNKVTPIVIDKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQDILDEIEKTTFHPSWGETRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQENGSIIWWQKEAKDLLPEGF
                     THPGSPNGEFTKETDIMDVWFDSGSSWNGVMNTKENLSYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMEILGQVSETYRKIRNTLRFLIANTSDFNPATDTVAYADLGAVDKYMT
                     IVFNQLVATITDAYERYDFMAIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLERRR
                     MQTVFYDILVKITKLLTPILPHTTEEIWSYLEHESEAFVQLAEMPVAETFSAQEDILE
                     AWSAFMTLRTQAQKALEEARNAKIIGKSLEAHLTIYASEEVKTLLTALDSDIALLLIV
                     SQLTIADLADAPADAVAFEGIAFMVEHAIGEVCERSRRIDPTTRMRSYNAFVCDHSAK
                     IIEENFPEAVAEGFEESDK"
     gene            complement(32870..33172)
                     /locus_tag="VCR92_000273"
     CDS             complement(32870..33172)
                     /locus_tag="VCR92_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEP4267372.1"
                     /translation="MRLINTTSSHPELIRNQLKNTDAYLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELDIIREFFLKRKIDPKIVIPGQSKTLHTNNLIEISFQTSV"
     gene            complement(33223..33678)
                     /locus_tag="VCR92_000274"
     CDS             complement(33223..33678)
                     /locus_tag="VCR92_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEP4267373.1"
                     /translation="MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWF
                     LPGGEIEAGEGQLQALERELIEELGFSATIGSYYGQADEYFYSRHRDTHFYHPAYLYE
                     VTAFQAVSKPLEDFNNLSWFSPIEAIAKLKRESHQWGVKEWQKKHHSTN"
     gene            complement(33806..36088)
                     /locus_tag="VCR92_000275"
     CDS             complement(33806..36088)
                     /locus_tag="VCR92_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEP4267374.1"
                     /translation="MLCQNCNLNESTIHLYTSVNGKQRQVDLCQNCYQIMKSDPANSI
                     LNGLTPGYRAQDRSTSPFFDDFFGDLNNFRAFGNLPNTPPTQAGQNGNGGGRYGGNYN
                     GQRPAQPQTPNQQAKGLLEEFGINVTDIARNGNIDPVIGRDEEITRVIEILNRRTKNN
                     PVLIGEPGVGKTAVVEGLAQKIIDGTVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERM
                     QKLMEEIRNRKDVILFIDEIHEIVGAGSAGDGNMDAGNILKPALARGELQLVGATTLN
                     EYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSPAAIEAAAHL
                     SNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYE
                     RAAYFRDQITKYKEMQAQKVDEQDIPIITEKTIEAIVEQKTNIPVGDLKEKEQSQLVN
                     LANDLKAHVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLA
                     IELFGSTNNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLD
                     EVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAR
                     EGRTSSVLGELSNFFSPEFMNRFDGIIEFKALSKEHLLHIVDLMLEDVNERLGYNGIH
                     LDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLEHPTEKQLRALMTNSE
                     NITIKAVKEGDSFLNEESLD"
     gene            36386..36616
                     /locus_tag="VCR92_000276"
     CDS             36386..36616
                     /locus_tag="VCR92_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEP4267375.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFSNDPEN
                     GPVFTLRDVEARESYSFDSIDLIAMEIYDLLY"
     gene            36743..37429
                     /locus_tag="VCR92_000277"
     CDS             36743..37429
                     /locus_tag="VCR92_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEP4267376.1"
                     /translation="MDLSFLPKYWAYFNYGVLVTIMISVSVVFFGTLIGVLVTLIKRS
                     HVKPLTWVVNLYVWIFRGTPMVVQIMIAFAWMHFNNMPTIGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPQNAMRYVILPQAFKNILPALGNE
                     FITIIKDSAFLQTIGVMELWNGAQSVVTATYSPISPLLVAAFYYLMVTTVMAQLLAVL
                     ERHMAQGGNH"
     gene            37429..38163
                     /locus_tag="VCR92_000278"
     CDS             37429..38163
                     /locus_tag="VCR92_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEP4267377.1"
                     /translation="MTEAIISIKDLHKYYGHNEVLKGIDLDIMPGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGQIRFEGIDITDKKNDIFSMREKMGMVFQQFNLFPNMTVLENI
                     TLSPIKTKGMAKAEADKTALSLLDKVGLSEKAKAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGVI
                     VEEGSPNQLFDLTKEERTKDFLSRVL"
     gene            38312..39721
                     /locus_tag="VCR92_000279"
     CDS             38312..39721
                     /locus_tag="VCR92_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HEP4267378.1"
                     /translation="MVSVMWFRRDLRIDDQKALAHAIASQSPTLCVFQFNKEQLNLLH
                     SRNQSSFITSVLAFRKLLKCESIDLYLMYGDLMTCFEQLLTQLKDWTDVYFNYDESGY
                     GRLRDQKAAQFFKKNGIAVHTYQDHYLHGSQEIINQSGQPYKVFTPYYRIWQNYPKET
                     PIKVELSQGRWLNLETPDDVLRTVESFKDEKYQDVATFDEASKQLNRFIQDQLAAYHA
                     NRDFPAQLGTSRLSPFLRIGAIGIRTVYHAVRQAPNSLGQATFLKELAWRDFYNMVYV
                     AYPDQKTQPIQKAFSQIEWVNNPDWFQLWKEGKTGYPIVDAAMLQLQKTGWMHNRLRM
                     IVASFLTKDLLCDWRLGEQYFQQQLIDYDAASNIGGWQWAASTGTDAVPYFRIFNPVT
                     QGKRFDPKGEFIKAYLPQLEHVPEKYLHEPWKMPKYLQESVSCIIGTDYPQPIVDHAK
                     QREQAIAKYEWAKEKAKIE"
     gene            39899..41593
                     /locus_tag="VCR92_000280"
     CDS             39899..41593
                     /locus_tag="VCR92_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEP4267379.1"
                     /translation="MTYNEVYQEWLHNNDLSDDIKADLAAIKDNEAEIQDRFYKTLEF
                     GTAGLRGKLGAGTNRMNTYMVGKAAQALANTIIDHGPEAVKKGIAVSYDVRYQSRTFA
                     ELTCSIMAANGIKAYLYKGIRPTPMCSYAIRALGCISGVMITASHNPQAYNGYKAYWQ
                     EGSQILDDIADQIAQHMAALTQYEEIKQMPFEKALDSGLVTYIDESIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLRRRGFENVYVVPEQEMPDPDFTTVGYPN
                     PEVPKTFAYSEKLGKAVDADILIATDPDCDRVALEVKNAVGDYVFLNGNKIGALLSYY
                     IFSQRFDLGNLPANPVLVKSIVTGDLSRAIASHYGIETVETLTGFKNICGKANEYDVT
                     KQKNYLFGYEESIGFCYGTFVRDKDAVSASMMIVEMAAYYKKKGQNLLDVLQTIYATF
                     GYYNERQIALELEGIEGQKRIARIMEDFRQTPIASVAEMALDKTIDFIDGYQDFPKQN
                     CLKFYLDDGSWYALRPSGTEPKIKFYLYTIGQTQENSATKLDAIEAACRTKINQVN"
     gene            41801..42655
                     /locus_tag="VCR92_000281"
     CDS             41801..42655
                     /locus_tag="VCR92_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEP4267380.1"
                     /translation="MTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDP
                     ASQVYVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPLPN
                     HINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLREYNVNLEGKH
                     AVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCRCADVLIVAIGQGHFITKQ
                     YIKDGAIVIDVGMNRDDNGKLIGDVAFDEVAEVAAKITPVPGGVGPMTIAMLLEQTYQ
                     SALRSTHK"
     gene            42808..44148
                     /locus_tag="VCR92_000282"
     CDS             42808..44148
                     /locus_tag="VCR92_000282"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEP4267381.1"
                     /translation="MADYLTVTHLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDESAVIQATMWAGVYKKLGFDLEEGMKINVIGRVQLYEPSGSYSIVIEKAEPDG
                     IGALALQFEQLKKKLTAEGYFEQKHKQPLPQFVSKIGVITSPSGAVIRDIITTVSRRF
                     PGVEILLFPTKVQGDGAAQEVVANIRRANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESQLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDLMSWIVERQN
                     RSYQACLRRIKQRQEWVDKLSQSVIFRQPERLYDAYLQKIDRLSMTLMNTMKDRLSSA
                     KENKVQLDHSLANSQLQTKIERYQDRVATAKRLLMANMASQYDSQLARFEKAQDALLS
                     LDASRIIARGYAMIEKNQALVASVSQITKGDQLTIKMRDGQLDVEVKDVKNENI"
     gene            44126..44341
                     /locus_tag="VCR92_000283"
     CDS             44126..44341
                     /locus_tag="VCR92_000283"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEP4267382.1"
                     /translation="MSKTKTFEENLQDLETIVNKLENGDVPLEEAISEFQKGMLLSKE
                     LQKTLQAAEKTLVKVMQADGTEVDMDD"
     gene            44341..45213
                     /locus_tag="VCR92_000284"
     CDS             44341..45213
                     /locus_tag="VCR92_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEP4267383.1"
                     /translation="MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPL
                     ILLEMIEGFGVSLQNAHFDLAAALEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKQFGE
                     ATAILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQA
                     LSLPQLSLIHLNKTGKLLTFPFKAAALVTEQAITVRQQLEQAGMLIGHAFQIRDDILD
                     VTASFEDLGKTPKKDLFAEKATYPSLLGLEASYQLLTESLDQALTIFQTLESDVGFKP
                     QIITKLIEGLRLNA"
     gene            45206..46033
                     /locus_tag="VCR92_000285"
     CDS             45206..46033
                     /locus_tag="VCR92_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEP4267384.1"
                     /translation="MPKERVDVLAYKQGLFETREQAKRGVMAGLVVSVINGQRYDKPG
                     DKIDDGTELKLKGEKLKYVSRGGLKLEKGLHVFGVSVANQIGIDIGASTGGFTDVMLQ
                     DGAKLVYAVDVGTNQLVWKLRQDPRVRSMEQYNFRYAQPEDFNEGQPVLASIDVSFIS
                     LSLILPALHNVLSDQGQVIALIKPQFEAGREQIGKKGIVKDKQIHEKVIQKVMDFASG
                     YGFTVKGLDFSPIQGGHGNIEFLAHLAKSQTPETLAPHLIQEVVAKAHKEFEKHEKE"
     gene            46020..46490
                     /locus_tag="VCR92_000286"
     CDS             46020..46490
                     /locus_tag="VCR92_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEP4267385.1"
                     /translation="MKKSERLELIKKMVLTHPIETQHDLLRLLAEHGLELTQATISRD
                     MNEIGIVKIPSGSGRYIYGLSQDSGKKIVQGPRSIKSTILAVSDKTKGLEQHLYLKVV
                     PGNSKLIKRYLLADFSKAIFSLIADDDSLLLIAKSPSEADMIRQEILLWMQGIT"
     gene            46512..48173
                     /gene="recN"
                     /locus_tag="VCR92_000287"
     CDS             46512..48173
                     /gene="recN"
                     /locus_tag="VCR92_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEP4267386.1"
                     /translation="MLLEISIKNFAIIDEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     MLGARASTEVIRRGANKAEIEGFFSVDATPELVACLESSGIAMEEELIIRRDIFANGR
                     SVSRINGQMVNLATLKQVGQFLVDIHGQHDQEELMRPQLHQQILDAFGDKAFEQLKEN
                     YQLIFDRYKSLRRQVIDKQKNEKEHKDRIDMLAFQIAEIEAAALSRGEDDRLNQERDR
                     LMNHKQIADTLTNAYVMLDNDDFSSLSNIRSSMNDLLSIEQFDSEYKGMSTSISEAYY
                     ILEEVSKQLSDTIDQLDFDGGRLQEIEFRLDTLNSLTRKYGGNVNDVLDYYDNIIKEY
                     QLLTGDDLSSGDLESELKALEKQLVAAATNLSERRHQLAEQLEAEIKAELKELYMEKA
                     DFKVHFTTSKFNRDGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISRKE
                     DKTSIVFDEVDTGVSGRVAQAIAQKIYKIGRHGQVLAISHLPQVIAIADYQYFISKES
                     KEESTVSKVRLLTPEERVEEIASMIAGTDMTQAALTQARELLAKH"
     gene            48345..49286
                     /locus_tag="VCR92_000288"
     CDS             48345..49286
                     /locus_tag="VCR92_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEP4267387.1"
                     /translation="MTSKKACLSSIIVLASLTCGNDTVSANHLSATGDKFDDCSTLVE
                     KDVAPKDELEMLAWSSSQTTDDADRDYEDFLDDDSFISQNETDKMFENLTDDRLLNKL
                     DELDELDELDEEDTIEPEQNVIMPSDDELFDLTDAVETRLTVSSAPHLEAELPKPHLR
                     SLSDTALRSGEIRGHLDNKLDALSVTATKLALTMAQKFDLTTHVYSIGESFSEVLAAH
                     YEDRKAESAFSKKKRFHLPIATPDVVIEELRRLVSSIGSSKEDVSVPYNRKLGMVVAK
                     RKIALPQTGEEFSYYPALLGLMILGLTPIMIPKKINN"
     gene            49502..50353
                     /locus_tag="VCR92_000289"
     CDS             49502..50353
                     /locus_tag="VCR92_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEP4267388.1"
                     /translation="MEKYMGTIKIVTDSSITIEPELIKALDITVVPLSVMIDSKLYSD
                     NDLKEEGHFLSLMKASKSLPKTSQPPVGLFAETYENLVKKGVTDIVAIHLSPALSGTI
                     EASRQGAEIAEAPVTVLDSGFTDQAMKFQVVEAAKMAKAGASLNEILAAVQAIKSKTE
                     LYIGVSTLENLVKGGRIGRVTGVLSSLLNVKVVMALKNDELKTLVKGRGNKTFTKWLD
                     SYLAKNSHRPIAEIAISYAGEASLALTLKERIAAYYNHSISVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            50346..51188
                     /locus_tag="VCR92_000290"
     CDS             50346..51188
                     /locus_tag="VCR92_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEP4267389.1"
                     /translation="MNNRHLFSGIFFFVISLCLAFLLLNIIIPKSNSRLKKSDFLTKE
                     QVAIQYVAIGDSLTEGVGDLTHQGGFVPLLTNDLSEYFKANVNHQNYGVSGDTSQQIL
                     DRMIKQKQIQLSLKKADIMTLTVGGNDVMAVIRKNLADLQVSSFRKPARQYQKRLRQI
                     IELARKDNKDLPIFILGIYNPFYLNFPELTDMQKVIDDWNTKTKEVVGEYDRVYFVPI
                     NDLLYKGINGQEGIVHSSGDQTTIVNDALFTGDHFHPNNTGYQIMSNAVMEKIKKHEK
                     KIKP"
     gene            51166..51753
                     /locus_tag="VCR92_000291"
     CDS             51166..51753
                     /locus_tag="VCR92_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEP4267390.1"
                     /translation="MKKKSNLNWWKWSFLCLLAFNTAFLMVIASRLIQVREPESELIA
                     KKPVKNIKIGTFVTTREQLNETVASYLKDYQTKKMSYKFYATSSSILFEGTYQLLGYE
                     VPLYIYFQPHRLENGAVQLQVISFSVGTLPLPEKDVLQYLKSSYKLPSFVKVMPNQSA
                     IVVNLQDIQNDAKVYLKAKKIDLFNDEISFNIYKK"
     gene            51852..52127
                     /locus_tag="VCR92_000292"
     CDS             51852..52127
                     /locus_tag="VCR92_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEP4267391.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSTIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGAEIEIAASKVPAFKAGKALKDAVK"
     gene            52481..54343
                     /gene="cadA"
                     /locus_tag="VCR92_000293"
     CDS             52481..54343
                     /gene="cadA"
                     /locus_tag="VCR92_000293"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEP4267392.1"
                     /translation="MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQVASAIFITA
                     FLIGGYASAKTGILDLVKNKHLSVDILMILAAIGAGIIGYWLEGALLIFIFSLSNTLE
                     EMAMEKSKDAISALMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQ
                     LLSPFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINL
                     VESAQEKKSKTATFIESLEDGYVKFVLVLIPAFILFSHFVLSWTWLAAFYRGMILLTV
                     ASPCALIASSTPASLAAISRAARKGLIIKGGDIVDNMGDIKAVVMDKTGTLTQGKPSV
                     VNAHYLEDELLVNRLVKGAETASTHPISKALLEYTEKLEPLTFDHLEEISGKGFQGFY
                     QGQEWRIGKKTFILEKVQDLSAFEETIQVEENQGKTLIFVSRDHQLIAYYALLDDIKI
                     ESKRAIKSLHAMGIKTVMLTGDQERTANYVAQKLGIDEVVANCMPQDKVAKLAELKTK
                     YGFVAMVGDGINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSIQLSRKM
                     KTIIKQNIVFALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK"
     gene            complement(54643..55578)
                     /locus_tag="VCR92_000294"
     CDS             complement(54643..55578)
                     /locus_tag="VCR92_000294"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004228450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEP4267393.1"
                     /translation="MVSTATQIGHFSFDNCLMNAAGVYCMTKEELMEVEKSQAASFVT
                     KTGTLEVRPGNPEPRYADTRLGSINSMGLPNNGFRYYLDFVSDLAKTGQHKPHFLSVV
                     GLSPTETETILKAIMASDYEGLVELNLSCPNVPGKPQIAYDFETTDQLLENIFTYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLSFVNCVNSIGNGLVIEDEQVLIKPKNGFGGI
                     GGDYIKPTALANVHAFYKRLKPSIHIIGTGGVKTGRDAFEHILCGASMVQIGTALHQE
                     GPAIFERVTKELKTIMVEKGYQSLDDFRGNLRYKD"
     gene            55817..56512
                     /locus_tag="VCR92_000295"
     CDS             55817..56512
                     /locus_tag="VCR92_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEP4267394.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDLAFTSVLTRAIKTTNLALENAGQLWVPTEKSWRLNERHYGALTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAM
                     PYWEEKIAPALLDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDE
                     KLNIVKEYYLGGE"
     gene            56619..57140
                     /locus_tag="VCR92_000296"
     CDS             56619..57140
                     /locus_tag="VCR92_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEP4267395.1"
                     /translation="MKAEDRRQKIIECLNSEQKAVSATRLGKLLGVSRQVIVGDIALL
                     RAQQIDIISTPKGYIMSTALYSHQFCARIVCQHNVEETKKELEIILAHQGIITTVEVE
                     HPIYGMITAPLNIKTHSDVTNFMSKLSQSKAELLSSLTEGLHSHLISCPSQEAFLAIK
                     HDLELAGILYKGI"
     gene            57301..57843
                     /locus_tag="VCR92_000297"
     CDS             57301..57843
                     /locus_tag="VCR92_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267396.1"
                     /translation="MTKKPTQLIAYTSILVAFAILIPIIMPLKLIIGPASFTLASHVP
                     LFLAIFMSIPVAILVALGTTLGFLLAGLPLIIVLRALSHLLFAILAAWWLSRKPQLMT
                     SAVKCFSFAFFINVIHGLAEFLVVYILTATTATSMSYFWSMLGLIGLGSLIHGILDFY
                     LALVLWRFLAKNLKLPTINA"
     gene            57967..58746
                     /locus_tag="VCR92_000298"
     CDS             57967..58746
                     /locus_tag="VCR92_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEP4267397.1"
                     /translation="MKTPEQILEATIHIGEHKVTKTFLAKSILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSIVGACAFPIGLIIILMAGGELITGNMMAVSAALLAKKIKFSE
                     LAKNWLIITLFNVIGAVFVAFVFGHFLGLTSAGIFKEEVIEVAHAKIAASPLQALVSG
                     IGCNWFVGLALWLCYGANDAAGKFLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     TWLDFATNFIFVYSGNIIGGAIFVSFLYFKVYYHPQKSKTQ"
     gene            59544..60140
                     /gene="recR"
                     /locus_tag="VCR92_000299"
     CDS             59544..60140
                     /gene="recR"
                     /locus_tag="VCR92_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEP4267398.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSNEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDTSRDQTTILVVEDAKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMDGKVSEVIVATNATADGEATSMYISRVL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            60241..61287
                     /locus_tag="VCR92_000300"
     CDS             60241..61287
                     /locus_tag="VCR92_000300"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEP4267399.1"
                     /translation="MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFIT
                     QMGQFIKTQQFSEKPSESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLRMPYIGTNVMSSSIAMDKITTKRVLESIGIPQVAYTVYIDGQDLEACLVE
                     TLARLTFPIFVKPANMGSSVGISKAQTKVELRKAIQLALTYDSRVLIEQGVVAREIEV
                     GLLGNDKVKSTLPGEVIKDVDFYDYQAKYVDNKITMAIPADVDQSIVTEMRSYAEVAF
                     KALGGCGLSRCDFFLTQDGQVYLNELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVT
                     LAQEMFDQRESHLI"
     gene            61486..62877
                     /locus_tag="VCR92_000301"
     CDS             61486..62877
                     /locus_tag="VCR92_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEP4267400.1"
                     /translation="MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLP
                     LKGQRDGHEFIDLAFQNGAVATFSEKELPGKPHLLVEDCLKAFQKLAHYYIDKMRVDV
                     IAVTGSNGKTSTKDMIGAVLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMG
                     QDHMGDIRLLSEIARPRIAVLTLVGEAHLEYFGSRDKIAQGKMQIVDGMNSDGILIAP
                     GDPIIDPYLPENQMVIRFGNQQEIDVTGIQEDKDSLTFTTNVLATPVSLPLPGKYNAT
                     NAMVAAYVGKLLAVTDEDIIAALQTVTLTGNRTEWKKAANGADILSDVYNANPTAMRL
                     ILETFANIAKNPGGKKIAVLADMKELGKDSVILHSQLIDSLTSGNIDQLVFYGDHIKE
                     LARLASQVYPAEQVHYFLKTEQEDQFEAMAQYVQNILNPFDQILLKGSHSMSLEKLVD
                     RLVTDKNCDSYQP"
     gene            62957..63652
                     /locus_tag="VCR92_000302"
     CDS             62957..63652
                     /locus_tag="VCR92_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEP4267401.1"
                     /translation="MDFFAIDPIGLPHTSLIFYLSSLLIALLLVFLTFQAYRLKSYRY
                     FFLFLQLSQVIGLYTWYVLRGFPLDEALPLYHCRIAMLAIFFLPDRNKFKQLFMVLGI
                     GGTFLALLSPDLYPFRLWHVANVSFYLGHYALLVNGLIYLLRFYDASQLRLLSVVRYL
                     ATVNFLLLLVSLATKGNYGFVMDIPVIHTRHLLLNFVIVTSGLTFMVKITEYFYLKFG
                     EAQQLAFAFSKEK"
     gene            63900..65444
                     /locus_tag="VCR92_000303"
     CDS             63900..65444
                     /locus_tag="VCR92_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEP4267402.1"
                     /translation="MSLTEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGDERFASIEDGDQLFANNPFYEQVKED
                     IELLQEAGNVFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGN
                     VVDPLAKDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFERGMGVNLTRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     PKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMTPMGKKTVRWISEDDLDQRMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     TLEEKM"
     gene            65751..67370
                     /locus_tag="VCR92_000304"
     CDS             65751..67370
                     /locus_tag="VCR92_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEP4267403.1"
                     /translation="MKFTEFNLSQDIQSAVVTAGFEKASPIQEMTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTNENIIQALVIAPTRELAVQSQEELFRFGREKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALILDHVETLILDEADEMLNMGF
                     LEDIEAIISRVPADRQTLLFSATMPAPIKQIGVKFMKDPEHVQIKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVNQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQIDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLSMIENLTKKQMKPLRPATAEEAFQAKKKVALKKIERDFADE
                     TIRSNFDKFKGDAVQLAAEFTPEELALYILSLTVQDPDSLPEVEIAREKPLPFKYVGG
                     GHGNKNGKGGRGRDNRNRGDRRGGYRGDRNRDERDGDRRRQKRDKRDGHDGSGNRDFK
                     RKSKRNSKDFFNKEKKSSAKNTGFVIRHKGE"
     gene            67497..69497
                     /locus_tag="VCR92_000305"
     CDS             67497..69497
                     /locus_tag="VCR92_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HEP4267404.1"
                     /translation="MSDSHLTAFDKASKAGFIIALGIVYGDIGTSPLYTMQSLVENQG
                     GVNQVSESFILGSISLIIWTLTLITTIKYVLIALKADNHHEGGIFSLFTLVRKISPWL
                     IIPAMIGGATLLSDGALTPAVTVTSAIEGLKAVPGLSHIYQNQTNVIITTLVILIVLF
                     GIQRFGTGFIGKIFGPVMFIWFSFLGVSGFFNTLGHLEIFKAINPYYALHLLFSPENH
                     RGIFILGSIFLATTGAEALYSDLGHVGRGNIYVSWPFVKMCIVLSYCGQAAWILANKH
                     SGIELNPFFASVPSQLRVYLVSLATLAAIIASQALISGSFTLISEAMRLKIFPLFRVT
                     YPGANLGQLYIPVINWILFAVTSCTVLAFRTSAHMEAAYGLAITITMLMTTILLKYYL
                     IKKGTRPILAHLAMAFFALVEFIFFLASAIKFMHGGYAVVILALAIVFVMFIWHAGTR
                     IVFKYVKSLNLNDYKEQIKQLRDDVCFDLYQTNVVYLSNRMQDHMIDRSILYSILDKR
                     PKRAQVYWFVNVQVTDEPYTAKYKVDMMGTDYMVRVNLYLGFRMPQTVPRYLRTIVQD
                     LMESGRLPKQEQEYTITPGRDVGDFRFVLIEERVTNARQLSNFERFIMQTKASIKHVT
                     ASPMRWFGLQYSEVTLEVVPLILSDVLKLPIKELVPVEDSEA"
     gene            complement(69521..69799)
                     /locus_tag="VCR92_000306"
     CDS             complement(69521..69799)
                     /locus_tag="VCR92_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEP4267405.1"
                     /translation="MTTKKAYMYVLECADKTLYTGYTTDLKKRLATHNAGKGAKYTRY
                     RLPVSLLYYEVFDSKEAAMSAEALFKKRKTRSQKLAYIATHQKEKKNH"
     gene            complement(69789..70643)
                     /locus_tag="VCR92_000307"
     CDS             complement(69789..70643)
                     /locus_tag="VCR92_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEP4267406.1"
                     /translation="MKADFSKVKITLQTFTSSLFYVKITGMIKAILKEGERIDQLFSS
                     DVGIIQNKDVFSYSIDSVLLSRFPKMPSKGLIVDLCSGNGAVGLFASTRTKAAIVEVE
                     LQERLADMGQRSIQLNQLEDQVTMICDDLKNLLNHVPRSGVDLMLCNPPYFKSHESSK
                     KNVSEHYLLARHEVTTNLEEICQVARHALKSNGRLAMVHRPDRFLEIIDSLRANGLAP
                     KRVQFVYPKLGKSANMLLIEAIKDGSIEGMTILPPLVVHKENGEYTDHIFEIYFGAAS
                     KGKPNHDH"
     gene            70683..71423
                     /locus_tag="VCR92_000308"
     CDS             70683..71423
                     /locus_tag="VCR92_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEP4267407.1"
                     /translation="MFYAYLRGLVVFLLWVVNGNAHYHHEEKMLDASENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFANRLFAWWIKMCGAFPIDRDKPSPDAIRYPVNM
                     LKKSNRSLLMFPSGSRHSQEVKGGVAVIAKLAKVKIMPAAYQGPMSVKGLLAGERVDM
                     TFGNPIDVSDIKRMNDEGIAEVANRIQAEFDRMDDELAPFQPGKARNPLTYLYRLPLG
                     LVLVVVLLLTILFSYIASFVWNPDKHRH"
     gene            71623..72285
                     /locus_tag="VCR92_000309"
     CDS             71623..72285
                     /locus_tag="VCR92_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEP4267408.1"
                     /translation="MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQ
                     SKAAVPALREISPVKQQVSEEKKEIQEDSSILVDLKGAVQKEGVYKLTASSRVRDVIE
                     LAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
                     INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIF
                     LD"
     gene            72266..74508
                     /locus_tag="VCR92_000310"
                     /pseudo
     CDS             72266..74508
                     /locus_tag="VCR92_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
     gene            74579..75619
                     /locus_tag="VCR92_000311"
     CDS             74579..75619
                     /locus_tag="VCR92_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEP4267409.1"
                     /translation="MIAIEKIEKLSKENLGLITLVTGDDIGQYSQLKSRLMEQIAFDK
                     DDLAYSYFDMSEAAYQDAEMDLVSLPFFAEQKVVIFDHLLDITTNKKSFLKEKDLKAF
                     EAYLENPLETTRLIIFAPGKLDSKRRLVKLLKRDALVLEANPLKEAELRTYFQKYSHQ
                     LGLGFESGAFEQLLLKSNDDFSQIMKNMAFLKAYKKTGNISLTDIEQAIPKSLQDNIF
                     DLTRLVLGGKVDVARDLIHDLRLSGEDDIKLIAIMLGQFRLYLQLAILAKEGKSEQQL
                     VTSLSEILDRRVNPYQVKYALKDSRTLSLAFLTGAVKTLIETDYQIKTGLYEKSYLVD
                     IALLKIMTHSQK"
     gene            75716..76321
                     /locus_tag="VCR92_000312"
     CDS             75716..76321
                     /locus_tag="VCR92_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEP4267410.1"
                     /translation="MAIILPELPYAYDALEPQFDAETMTLHHDKHHATYVANTNAALE
                     KHPEIGENLEELLADVTKIPEDIRQALINNGGGHLNHALFWELLSPEKQDVTPDVAQA
                     IDDAFGSFDAFKEQFTAAATGRFGSGWAWLVVNKEGQLEITSTANQDTPISEGKKPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSELYQAAK"
     gene            76488..76714
                     /locus_tag="VCR92_000313"
                     /pseudo
     CDS             76488..76714
                     /locus_tag="VCR92_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922433.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            76699..76947
                     /locus_tag="VCR92_000314"
     CDS             76699..76947
                     /locus_tag="VCR92_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267411.1"
                     /translation="MDADLAQMDALGLYYDDNHLSLVNTVKVYLKEFGIGESQIAFSY
                     KDLNSGRTAAMNDHQPMIAGSTYKLPLNMLVVDKANYP"
     gene            76944..77534
                     /locus_tag="VCR92_000315"
     CDS             76944..77534
                     /locus_tag="VCR92_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEP4267412.1"
                     /translation="MTERFDITETDYEYDQEHHAYVAQFNGAMSIPDMQEYSLVYSEN
                     TPAYALAERLGGMNKAYQLFDRYGKVSGAITTIDRNGNKITTAYYLQGLDYLWQHQDK
                     YKDILYYIGESFPDLYYKTYLPHVKVYQKPGYVREALNVGAIVCEESPYLITLYSSGL
                     GGATQASEEVNGLGYVQLVQLTYVINEWHRVNHNMI"
     gene            complement(77648..78868)
                     /locus_tag="VCR92_000316"
     CDS             complement(77648..78868)
                     /locus_tag="VCR92_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEP4267413.1"
                     /translation="MKLLGKWLFFLMFLTFCVSFWQKDYQRIAFEKEHKLYQNLVAPF
                     YQNYPKLRELQLSEAIKLRHDLLDYVRKLDKDGWSYKAIQKGYLEQLAVRGNSYHFEQ
                     LYSRIRLIGSPDFQKLWQQEEMAQTPQEAQKRLQLLLTYLKMPDELTGQSKQTQQVLA
                     QLSPKLSPTDPFWDQLSTLIQAYYVNLEHIPYSRFNRKIHQLRYLISTQQTEWVRSHY
                     GNKGKTDADALAKYLATLEDDDYALYESSRYHNKVASILDANGNHQAVYTDNIPQANY
                     KILIHFHSEFILSESGQFLVALDPDNLTRNSIVNGSSFNYGNQNDDLHRLLDIDPILL
                     FDPAFIEKAINSPDATFLVPDLEQQRDKHNPIYSRNGKSSKQLTRAAVKKFKKLLHHY
                     QETRGDNKTSKTQH"
     gene            complement(78875..79903)
                     /gene="queA"
                     /locus_tag="VCR92_000317"
     CDS             complement(78875..79903)
                     /gene="queA"
                     /locus_tag="VCR92_000317"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEP4267414.1"
                     /translation="MNTNDFDFELPEELIAQTPLEKRDSSKLLIIDHRQKTMVDSHFD
                     HIIDQLNPGDALVMNNTRVLPARLYGEKPDTHGHVELLLLKNTQGDQWEVLAKPAKRL
                     KVGSQVNFGDGRLKATIIDELEHGGRIVEFSYDGIFLEVLESLGEMPLPPYIHEKLED
                     AERYQTVYAKENGSAAAPTAGLHFTTDLLKKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHDMHSEFYSLSEEAAQTLRDVKQAGGRVVAVGTTSIRTLETIGGKFQGDIQADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYRHAVDEKYRFFS
                     FGDAMFVN"
     gene            80105..80809
                     /gene="nagB"
                     /locus_tag="VCR92_000318"
     CDS             80105..80809
                     /gene="nagB"
                     /locus_tag="VCR92_000318"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEP4267415.1"
                     /translation="MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQ
                     EMVKSPLDFSDLTSINLDEYVGLSVESDQSYDYFMRQNLFNAKPFKKNYLPNGLATDI
                     EAEAKRYDQIIAEHPIDFQVLGIGRNGHIGFNEPGTSFEEETHVVDLQESTIKANSRF
                     FTSIEDVPKQAISMGIASIMKSKMIVLLAFGQEKADAIKGMVFGPITEDLPASILQKH
                     DHVIVIVDEAAASQLD"
     gene            80928..81644
                     /locus_tag="VCR92_000319"
     CDS             80928..81644
                     /locus_tag="VCR92_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEP4267416.1"
                     /translation="MRLDKLLEGTKVGSRSQVKKLIKAQGVWVDHMPARNGRQNVDPG
                     LQLIEVTGQRVTHPKHSYIILNKPSGVVSAKKDTNYLTVIDQLAEEDKSPDLYPVGRL
                     DRDTEGLVLLTDNGPLGFRMLHPIHHVSKTYLVTVNGLLAEDASDFFAAGICFPTGEQ
                     CQPAQLTILKADTDQSQASLTISEGKFHQVKKMFLTYGLKVTSLKRTHFAGLELGHLA
                     SGEYRYLTASERQLIKTYLD"
     gene            81939..82901
                     /locus_tag="VCR92_000320"
     CDS             81939..82901
                     /locus_tag="VCR92_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEP4267417.1"
                     /translation="MTKILTALDGKNQLISLVTQPISTKPPFCCPACKSPVRLRQGTI
                     RRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLVRTEAVCIEKYLPELQQIADLWV
                     NDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
                     SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYS
                     YQKKMTVNLSKRIQRALLARHPKWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSG
                     FCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK"
     gene            82914..84719
                     /gene="pepF"
                     /locus_tag="VCR92_000321"
     CDS             82914..84719
                     /gene="pepF"
                     /locus_tag="VCR92_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEP4267418.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEIDAAKDFS
                     GHLLDSSANLLTITDTYLELARRVEKVYVYAHMKNDQDTTVAKYQEYQAKASGLYAKF
                     SEVFSFYDPEVMALSQEDYQAFLAETPDLKRYHHFFDKLFQTRDHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIVFPVVKNDKGEDVELTHGNFISLMESKDRSIRQAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGKDYA
                     DRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQKGEVLTSEYLNQLYADLNEKYYGLSKKDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFKVFDERLTELEVLVSKGIHKS"
     gene            85095..86291
                     /locus_tag="VCR92_000322"
     CDS             85095..86291
                     /locus_tag="VCR92_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEP4267419.1"
                     /translation="MEKTKRYIIATAGILLHLMLGSTYAWSVYRNPILQETGWDQAPV
                     AFAFSLAIFCLGLSAAFMGNLVEQYGPRLTGTVSAILYASGNMLTGLAIDRKEIWLLY
                     IGYGVIGGLGLGAGYITPISTIIKWFPDKRGMATGFAIMGFGFASLLTSPIAQWLIET
                     EGLVATFYLLGLIYLIVMLFASQLIIKPTAAEIAILDKKRLQNNSYLIEGMTAKEALK
                     TKSFYCLWVILFINITCGLGLISVVAPMAQDLTGMSPEMSAIVVGAMGIFNGFGRLVW
                     ASLSDYIGRRVTVILLFLVSIIMTISLIFAHSSLIFMISIATLMTCYGAGFSLIPPYL
                     SDLFGAKELATLHGYILTAWAIAALTGPMLLSITVEWTHNYLLTLCVFIVLYILGLMV
                     ALRLKK"
     gene            86357..87064
                     /locus_tag="VCR92_000323"
     CDS             86357..87064
                     /locus_tag="VCR92_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEP4267420.1"
                     /translation="MVKSYSKTANHNMRRPVVKEELVHYMRTRQKQITGFLAELEQFA
                     RQENIPIIQPEVVAYFRFLLQSLQPKHILEIGTAIGFSALLMAENAPDATIVTIDRNR
                     EMIDFAKANFAKYDSRQQIRLLEGDAADILSTLEGNFDFVFMDSAKSKYIVFLPEILR
                     LLKVGGVVILDDVFQGGDITKPIEDIRRGQRTIYRGLQSLFDATLTHPNLTTSLVPLS
                     DGLLMIRKNQADILLPD"
     gene            87127..88182
                     /gene="prsA"
                     /locus_tag="VCR92_000324"
     CDS             87127..88182
                     /gene="prsA"
                     /locus_tag="VCR92_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEP4267421.1"
                     /translation="MKNSNKLIASVVTLASVMALAACQSTNDNTKVISMKGDTISVSD
                     FYNETKNTEVSQKAMLNLVISRVFEAQYGDKVSKKEVEKAYHKTAEQYGASFSAALAQ
                     SSLTPETFKRQIRSSKLVEYAVKEAAKKELTTQEYKKAYESYTPTMAVEMITLDNEET
                     AKSVLEELKAEGADFTAIAKEKTTTPEKKVTYKFDSGATNVPTDVVKAASSLNEGGIS
                     DVISVLDPTSYQKKFYIVKVTKKAEKKSDWQEYKKRLKAIIIAEKSKDMNFQNKVIAN
                     ALDKANVKIKDKAFANILAQYANLGQKTKAASESSTTSESSKAAEENPSESEQTQTSS
                     AEEPTETEAQTQEPAAQ"
     gene            88569..91187
                     /gene="alaS"
                     /locus_tag="VCR92_000325"
     CDS             88569..91187
                     /gene="alaS"
                     /locus_tag="VCR92_000325"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEP4267422.1"
                     /translation="MKELSSAQIRQMWLDFWKSKGHCVEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPDWFDFPKDKLYMTYYPDDKDSYNRWIACGVEPSHLVPIEDNFWEI
                     GAGPSGPDTEIFFDRGEDFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPNKNIDTGAGLERLAAVMQGAKTNFETDLFMPIIREVEKLSGKTYNPDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGINETFLYKLVPTV
                     GQIMESYYPEVLEKRDFIEKIVKREEETFARTIDAGSGHLDSLLAQLKAEGKDTLEGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKSAMKEQQDRARAAVVKGGSMGMQNE
                     TLAGIVEESRFEYDTYSLESSLSVIIADNERTEAVSEGQALLVFAQTPFYAEMGGQVA
                     DTGRIKNDKGDTVAEVVDVQKAPNGQPLHTVNVLASLSVGTNYTLEINKERRLAVEKN
                     HTATHLLHAALHNVIGEHATQAGSLNEEEFLRFDFTHFEAVSNEELRHIEQEVNEQIW
                     NALTITTTETDVETAKEMGAMALFGEKYGKVVRVVQIGNYSVELCGGTHLNNSSEIGL
                     FKIVKEEGIGSGTRRIIAVTGRQAFEAYRNQEDALKEIAATVKAPQLKDAAAKVQALS
                     DSLRDLQKENAELKEKAAAAAAGDVFKDVQEAKGVRFIASQVDVADAGALRTFADNWK
                     QKDYSDVLVLVAAIGEKVNVLVASKTKDVHAGNMIKELAPIVAGRGGGKPDMAMAGGS
                     DASKIAELLAAVAETV"
     gene            91548..91763
                     /locus_tag="VCR92_000326"
     CDS             91548..91763
                     /locus_tag="VCR92_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4267423.1"
                     /translation="MEVILKNRLKELRARDGINQTEMAKLAGVSRQTISLIERNEYTP
                     SVIIAMKIAKVFQEPVEEVFRLVEVEE"
     gene            91760..92521
                     /locus_tag="VCR92_000327"
     CDS             91760..92521
                     /locus_tag="VCR92_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEP4267424.1"
                     /translation="MKKKKNSFLRLLKMLLLSSLAGGIIGGMVGAFLGYHGERLDQLT
                     FLKDDVINLIILLNRLVVVTGLTLSFVFLTQLKKETAVYNTIEEDDYSENGYRQLNKK
                     HAYTMLLIAVASILSMCNVLLGLTLTNDSQHAMLAIPLLDILLLLMVIPFQALAMKRY
                     NAIRGTDVPYFPNLKELKHNIMALDEAELQAYHKTSFESVLSLNGVIIPSLYVILFFV
                     YLFTGQVELTAILVLVLIQLYLLVKSATMTRQFYR"
     gene            92540..93235
                     /locus_tag="VCR92_000328"
     CDS             92540..93235
                     /locus_tag="VCR92_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEP4267425.1"
                     /translation="MKGFINYLKIAVLIILAMVFNVLPMILLQKQHDIPMVLNWGIGI
                     FYLVIVGSVLIVLWRLYQAKQDTPIKQQKMRLVDWGYLALFWLIIRVIAIAGTLVNQL
                     WSGQQVSANDAAIHTLARLIKGGFPLYTALFVLVIAFIAPIMEELVFRGFPMIDLFKG
                     KSLKVAGLVTSLVFALPHATNSVEFIMYSCMGIFLFVAYQRRGNLKDAILLHIFNNLI
                     EVILLMSIGLGVI"
     gene            complement(93329..>93726)
                     /locus_tag="VCR92_000329"
     CDS             complement(93329..>93726)
                     /locus_tag="VCR92_000329"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEP4267426.1"
                     /translation="VGWAMGQRMQDKLVTEAFNQAYNREKPKEGVIVHTDQGSQYTGA
                     RFQDLLRWKKCKSRMSRKGNPYDNALMESFYKTLKRELVNDAHFATIEQAKLEIFKYS
                     ETYYNPKRLHSALGYLSPVEFEKNSYSLA"
BASE COUNT        29229 a        16272 c        19604 g        28621 t
ORIGIN      
        1 gctgtgagaa ataccctatt tttatctttt ttaaggagta cactaggaat ataagcaaga
       61 gttaagaatc ttgacggtga attcacaaaa accaattaga aagaggtaat tcttatgact
      121 gctcaaacac caattcatgt ttattctgaa attggaaaat taaaaaaagt gttgctccac
      181 agacccggta aagaaattga aaatcttatg ccagactact tggaacgctt gttgtttgat
      241 gatattccat tcttagagga tgcccaaaaa gaacatgatg cttttgccca agctttgcgt
      301 gacgaaggta ttgaagtctt gtaccttgag accttagctg cagaatctct tgtcactcca
      361 gaaattcgcg aagctttcat cgatgaatac ctaagtgaag ctaatatccg tggaagagct
      421 actaaaaaag ccattcgtga attgttgatg gctatcgaag acaatcaaga attgattgaa
      481 aaaaccatgg caggagttca aaaatctgaa cttccagaga tcccagcatc tgaaaaaggc
      541 ttgactgact tggttgaatc caattaccca tttgcgatcg acccaatgcc aaacctttat
      601 ttcacacggg acccattcgc aactatcggt acaggtgttt ctcttaacca catgttctca
      661 gaaacacgta accgtgaaac cctttatggt aaatacattt tcactcatca cccaatttat
      721 gggggtggca aagtgcctat ggtttatgac cgtaatgaaa ccactcgcat tgaaggtggg
      781 gacgaacttg ttctttcaaa agatgtgctt gcggttggta tttctcaacg tacagatgct
      841 gcttctattg aaaaattgtt ggttaacatc tttaaacaaa accttggctt caagaaagta
      901 ttggcctttg aatttgcaaa taaccgtaaa ttcatgcact tagacactgt ctttaccatg
      961 gttgactatg acaaatttac cattcaccca gaaattgaag gcgaccttcg tgtttactct
     1021 gtcacttacg acaatgaaga acttcatatc gttgaagaaa aaggtgattt agcagaactt
     1081 cttgctgcta accttggtgt tgaaaaagtt gaccttatcc gttgtggtgg tgacaactta
     1141 gtagcagcag gtcgtgaaca atggaacgat ggttctaaca cccttactat cgcaccaggt
     1201 gtggttgtgg tttataaccg taacaccatt accaatgcta ttcttgaatc taaaggcttg
     1261 aaattgatca agattcacgg aagtgaattg gttcgcggtc gtggtggacc tcgttgtatg
     1321 tcaatgccat ttgaacgtga agatatttaa taagctatgg taaaggtggt tataggtcag
     1381 aagccttttt aaagggcagc tagtgtttat cttcgcttct gtgtctttgt ccttcaatga
     1441 aattttgtca tgacagataa atttgatgcc aatgacgaaa caagaacggt ttatgcagtc
     1501 gtttatgaca atgaccagcc cgtttcaaca ggacaatttt tagctgaaac gaaaatagaa
     1561 gcacgattga cacgcattgt aaccttagca gattattgtg gttgcggtta tggtgccaaa
     1621 gtcactgaag cgctagaaac ttataccaga cgagaaggct tttaccaact aaccattcac
     1681 agtgaactga cagcacaaac cttttatgaa aacctaggtt atcagtccta tggtcccaag
     1741 tgtttagaag atggtgagta ttgtcagtcc cttgcaaaaa ccattcttaa atgggagaag
     1801 aatatggaca tagcaatgct aattgcgatt gttggtggtc tattaggctg ctatctctat
     1861 ctcacaaaaa ataattaatc aaaacagatt acagttaaca ctcgaaggag acaatagatg
     1921 acacaagtat ttcaaggacg tagcttccta gcagaaaaag attttacacg cgctgaatta
     1981 gaatacctta ttgatttttc agcacatttg aaagatttga aaaaacgtgg tgtgcctcat
     2041 cactacttag aaggtaaaaa cattgccctc ttgtttgaaa aaacatcaac tcgtacgcgt
     2101 gcagctttta caacagcagc cattgaccta ggtgctcacc cagaatacct cggtgccaat
     2161 gacatccaac ttggtaaaaa agaatcaaca gaagacactg ctaaagtatt gggtcgtatg
     2221 tttgatggga ttgaattccg tggctttagc caacgcatgg ttgaagaatt ggcagaattc
     2281 tcaggtgtgc cagtttggaa tggtttgact gatgaatggc acccaaccca aatgcttgct
     2341 gactatttaa cagtgaaaga aaactttggc aaacttgaag gccttaccct tgtttactgt
     2401 ggtgacgggc gtaataacgt tgccaattcc cttcttgtga ctggtgctat ccttggtgtt
     2461 aatgttcata tcttctcacc aaaagaactt ttcccagaag aagagattgt gacattggct
     2521 gaaggctatg ctaaagaaag tggcgctcgt atccttatca cagaagatgc tgacgaagct
     2581 gttaaaggcg cagacgtgct ttacacagat gtttgggtat caatgggtga agaagacaaa
     2641 ttcaaagaac gtgttgaatt gcttcaacca tatcaagtca acatgaacct tgttcaaaaa
     2701 gcaggaaatg acaagcttat cttcttgcac tgcttgccag ctttccatga cacaaatacc
     2761 gtttatggta aagacgttgc tgaaaaattc ggcgtgaaag aaatggaagt cactgatgaa
     2821 gtcttccgca gcaaatacgc tcgtcatttt gaccaagctg aaaaccgcat gcacactatc
     2881 aaagcggtta tggcagcaac ccttggtaac ctctttattc caaaagtgta ataaggactg
     2941 gtactcctta actcatttca catatcaatg tgaccccttt aatttaacaa tttaactact
     3001 taaaaacgta ctttaactac atgacaagtc gttctggttt tcgcgtcctt gaccggaact
     3061 agaacggctt atttttatga aaaggtaaga ggtaatcatt atgacagaag aaaaaaaacg
     3121 gggttttaga attccttctt cttacaccgt tctttttatc attatagcca tcatggcagt
     3181 gttaacttgg tttattccag ctggcgccta cgaaaccgct aagggcggtg gtgttatttc
     3241 aggaacctac aaaacagtag catccaatcc tcaaggattt tttgacatct tgatggctcc
     3301 cgttcgaggc atgttaggtg ttgaaggcac tgatggtgct attcaagtgt ctttctttat
     3361 cttaatggtt gggggctttt taggagttgt caacaaaaca ggtgctcttg acacagggat
     3421 tgcgtcagtg gttcgtaaaa acaaaggtag agaaaaaatg ctgattgcta ttttaatccc
     3481 tttgtttgct ctaggtggaa cgacctatgg tatgggggaa gaaaccatgg ccttttaccc
     3541 acttttaatt cctgttatga ttgcggttgg ttttgacagt attgttgctg tagccattat
     3601 tttgattggt tctcaaattg ggtgtctagc ctccactatt aacccatttg caactggtgt
     3661 agcagctgat gctgctggtg tcagcattgc agatggaatg atttggcgtg ttatccaatg
     3721 ggttattctt gtcggcatgt ctatttggtt tgtttacaat tacgctagta agattgaaga
     3781 agacccaagt aaatcattgg ttgcagacaa ggaagaagag cataaggaac tcttccagtt
     3841 gcaaaattct ggagaagact taaacaagcg ccaacgaaac gttttgacca tttttacttt
     3901 gacctttgtc attatgattc ttagtttgat tccgtgggaa gattttggca tcaaattctt
     3961 taccaatatc aatacttggt taaccacaat gcctatctta gggggagtta ttgggaaaac
     4021 catgggagca tttggtactt ggtatttccc agaaatcacc atgctcttta tcatgatggg
     4081 tgtcttagtt gctattgttt atcgtatgag tgaagaagac ttttttagct cttttttgac
     4141 tggtgcaggt gaatttttag gtgttgccat gatctgtgct attgcacgcg gtattcaagt
     4201 tatcatgaat ggtggtatga ttacagccac tatcttacac ttaggtgaaa caagtctttc
     4261 tggtttatct tctcaagttt ttgtgatatt agcttatatt ttctacctcc caatgtcctt
     4321 cttgattcca tcaacatcag gacttgctgg ggctacaatg gggattatgg caccgcttgg
     4381 acaattctca aatgtccctg ctcaccttgt tattacagcc ttccagtcag cttctggaat
     4441 cttaaacatg atttctccaa cttcagcaat cgttatggga gcacttgcgc ttggtcgcgt
     4501 tgaccttggt acttggtgga aattcattgg taaatttatt gtaatggtga tgcttgtaag
     4561 cgtgctatta cttgtagttg caacattctt ttaacagata ggaggttcct atggaatcct
     4621 atatcacacc taaacatcaa gaggcctgtg tagctgccat taaacagatc gtttcttacc
     4681 cttctgtttg tcatgaagga gaaaatggca caccttttgg acaggccatt caagatgttc
     4741 tcgaagcaac cttagactta tgtcaaggtc ttggttttca tacttatatt gatcctgaag
     4801 gttactatgg ctatgctgag ttaggtgacc aaaaagaggt cttggctatt ctttgccatt
     4861 tggacgttgt tccagaagga gatcgtcagt tatggaagac agatcctttt gactgtgttg
     4921 aggcagacgg ctgtttattt ggtcgaggca ctcaagacga taaagggcct actatgatgg
     4981 cgctatttgc caccaaagcc ttgatagatg caggtgttac ctttaataaa cgcattcgtt
     5041 ttattttcgg aacagatgaa gaaactttgt ggcggtgtat gaatcgctac aatgatgtag
     5101 aagaacaggc tacctttggg tttgctcctg attcaagttt ccctttaacc tatgccgaaa
     5161 aaggcctact tcaggcaaaa ttagtgggga aaggttctga taaactgtca cttgaaatcg
     5221 gacaagccta caatgttgtt cctgcaagag cttcttataa aggcaataag cttgaggctt
     5281 tacaaaaaga actagataag cttggctttg agtacgtcgt caaagaggga gaattaacgg
     5341 tttatggtct cgcccaacat actaaagatg ctcccgatgg catcaacgct atgattaggc
     5401 ttgccaaggc tttagtggtc cttgaaccta acaaaaccct tgattttctt gctaatgtca
     5461 ttgatgaaga tggcagagca cttaatattt ttggcagaat cgaagatgaa ccttcaggca
     5521 aattaagctt taatgccgca gggcttacct taaccaaaga caaagcagaa attcgcctag
     5581 atattcggat tccagttttg gcagataagg aaaaattagt ccaacaatta agccaaaaag
     5641 cacaagaata cggcctaacc tatgaagaat ttgattattt ggccccatta tatgtgccat
     5701 tagacagtga attggtaaca accttgttat ctgtctatcg gaaaaaaaca ggtgatcaaa
     5761 gccctgccca atcatcagga ggggcaacct ttgctagaac aatgaagaat tgtgttgcct
     5821 ttggtgccct tttccctgat gctgttcaaa cggaacacca agaaaatgaa catattgttt
     5881 tagcggatgc ttaccgcgct atggatattt atgcggaagc tatttaccga ctaacgcgat
     5941 aacaagatat gaggagtaat tatgacgaaa caaaaaatcg tagtcgcact tggaggaaat
     6001 gctattcttt caacagatgc gtcagcaaaa gcacaacaag aagccttgat ttccacatca
     6061 aaatcattgg ttaaattaat taaagaaggt catgaagtca tcgtgaccca cggcaatggc
     6121 ccacaagttg gtaatctctt attacaacaa gcagcggcag attctgaaaa gaatccggct
     6181 atgcctttgg acacttgtgt tgccatgaca gaaggtagca tcggtttttg gttagttaat
     6241 gcccttgata atgaattgca agcccaaggt attcaaaaag aagtggcagc tgttgtcact
     6301 caagtgatcg tggatgccaa agacccagct tttgaaaacc caacaaaacc aattggtcca
     6361 tttcttaccg aagaagatgc caaaaaacaa atggcggagt ctggtgcaag tttcaaagaa
     6421 gatgcaggtc gtggctggcg taaggttgtg ccatcaccaa aaccagttgg tattaaagaa
     6481 gccaatgtca tcagaagtct cgttgattct ggcgttgttg tggttagtgc tggtggtggc
     6541 ggtgtgcctg ttgtggaaga tgcaactagc aagtccttga ctggtgtgga agctgttatt
     6601 gacaaggact ttgctagcca aaccctttca gaattggtgg atgcagacct ctttatcgtt
     6661 ttgacaggag ttgacaatgt ttacatcaac ttcaacaaac ctgaccaagc caaattggaa
     6721 gaagtgactg tctctcaaat gaaagaatac atcacacaag accaatttgc accaggtagt
     6781 atgttaccaa aagtggaagc tgccattgct tttgttgaaa acaaaccaaa tgctaaagcc
     6841 attatcacat cgctagaaaa tattgacaat gtactatcag caaacgctgg aacacaaatt
     6901 atcgcagggt aatcaagagg atttttagtt ctgtttaaaa gactcattta atggtatttt
     6961 ctgaagagta cgactgacat aaagagttga tactgttttt aaaggaaaag agtgtgccat
     7021 aataaaaaac aatagtagta ttagaaaagg ctaattttat tgagaattag ccttttcttt
     7081 tagctttgat aggtgtataa taaccatact attttttatt tttcaaaata ttagaataaa
     7141 caaaagtgga caacgtataa agagaactgc taagtcgttg agttcattag tcccaaaaag
     7201 attaccaaaa atgaaggagg agctatgaag aaaagtttta ttcatcaaca agaggagatt
     7261 tcctttgtta agaatacgtt cactcagtat ttgattgcta agttagatgt tgttgaagtg
     7321 caaggaccca ttttaagtcg ggtcggggac ggtatgcaag ataatttgtc cggtactgaa
     7381 aatccagtat ctgtcaatgt cttgaaaatt cctaatgcaa cctttgaagt tgtgcattca
     7441 ttagcaaaat ggaaacgtca caccttagcc cgttttgggt ttaatgaagg tgaaggcctt
     7501 gttgttaata tgaaggctct ccgacctgat gaggattcac ttgaccaaac ccattctgtc
     7561 tatgttgacc aatgggactg ggaaaaagtc atccctgatg gcaaacgtaa tctcgcttac
     7621 ctcaaagaaa ccgttgaaac catttacaag gtcattcggt taactgaatt agctgtagaa
     7681 gctcgttatg atattgaggc tgttttacct aagaaaataa ccttcattca taccgaagaa
     7741 ttggtagcta aataccctga tttgacgccc aaagaacgtg aaaatgccat tactaaagaa
     7801 tttggagcag tctttttaat tggtattggc ggggttttac ctgacggtaa accacacgat
     7861 ggccgcgctc ctgactatga tgactggaca acagaaactg aaaatggcta tcatgggctt
     7921 aatggtgata ttttggtttg gaatgaccaa cttggttcag cctttgaatt atcctcaatg
     7981 gggatccgtg tggatgaaga ggccctaaaa cgtcaggtgg aaatgactgg tgaccaagac
     8041 cgcttagcct ttgattggca caaatctttg ttgaatggac ttttccctct aacgattggt
     8101 ggaggaatcg gtcaatcacg tatggtcatg tttttgttgc gtaaaaaaca tattggagaa
     8161 gttcagacct ctgtttggcc ccaagaagtt cgtgatagct acgataatat tttataagta
     8221 atcacatcat tttgctaagt tttccacttg tataagagac tttaaataaa tgatcagaaa
     8281 tattgaaaaa agaaatcatt tttaaggttt agagctagaa atttgctata ataaatatta
     8341 tgagagttgt atcaggtgaa tttggtgggc gtcctttaaa gacgctcgat ggaaagataa
     8401 cacgccctac ttcagacaaa gttagaggtg cgatttttaa tatgatagga ccttacttta
     8461 atggtggtcg tgttttagat ttgtttgcag gttcaggtgg attagccatt gaggctgttt
     8521 ctcgtgggat gtctgctgca gttttggttg agaagaatcg taaagcgcaa gctattattc
     8581 aagacaatat tataatgact aaagctgaga atcggtttac cttgttaaaa atggaagctg
     8641 agcgagctat tgattgcttg actggtcgat ttgacttagt ctttttagac cctccttatg
     8701 ccaaagaaac aattgtggca actattgaag ctttagcagc taaaaactta ttgagtgaac
     8761 aggttatggt tgtctgtgag acagataaaa cagtcttgtt gccaaaagag attgcaacgt
     8821 taggtatttg gaaagaaaaa atttatggaa ttagtaaggt aacagtttat gttaactaaa
     8881 ataggacttt atacagggtc atttgatcct gttacaaacg gtcatctcga tattgttaaa
     8941 cgggcaagtg gcctatttga tcaaatatat gttgggattt ttgataatcc taccaaaaaa
     9001 agctatttta aactagaagt tcgtaaagca atgcttactc aagctctggc tgattttaca
     9061 aatgtaattg tagtaacttc gcacgaacgt ttagctattg atgtagctaa agaattacga
     9121 gtaactcact tgattagagg cttgcgaaat gcaactgact ttgagtatga agaaaatttg
     9181 gaatatttta atcacctttt agctccaaat attgagaccg tctatttgat atcaagaaat
     9241 aaatggcagg cccttagctc tagtcgtgtg agagagctaa ttcattttca gtcttcctta
     9301 gaaggtttgg ttcctcagtc agttattgct caagtggaga aaatgaatga aaagacttaa
     9361 aaaaatcaaa tggtggttag tgggtctgct agctttaatc tctttgttgc tagcgttatt
     9421 ttttccgcta ccttattata ttgaaatgcc tggaggcgct tacgatattc ggactgtctt
     9481 acaagtcaat ggcaaagaag acaaacgaaa aggagcttac cagtttgttg cagtgggcat
     9541 tagtcgtgcc agcctcgcgc agctattata tgcttggctg acaccgttta ctgaaattag
     9601 tacagcagaa gatacaacag gcggatacag cgatactgat ttccttcgaa ttaatcaatt
     9661 ttacatggaa acatcacaaa atgcagctat ttatcaagct ttatccttag ctggaaaacc
     9721 agttacatta gattataaag gcgtatatgt tttagacgta aacaacgaat ctacttttaa
     9781 aggaacgtta cacttagcag atactgtaac aggtgtaaat ggtaaacagt ttactagttc
     9841 agcagaactt attgactatg tttctcacct aaaactaggg gatgaagtta cggttcagtt
     9901 tacgagtgat aataagccta aaaaaggagt tggccgtatt atcaaactga aaaatgggaa
     9961 aaatgggatt ggcattgcct tgactgatca tacaagtgtc aattcagaag acacagtgat
    10021 ctttagtact aaaggagtag gaggacctag tgctggtcta atgtttactc ttgatatata
    10081 tgatcaaata actaaagaag atttacgcaa gggccgtaca attgcaggta caggaactat
    10141 tggcaaggat ggcgaagtag gagatattgg tggtgcaggt cttaaagtag ttgcagcagc
    10201 tgaagctggt gcagatatat tttttgttcc gaataatcct gttgataagg aaattaaaaa
    10261 agttaatcca aatgctataa gtaattacga agaagccaaa cgggcagcca aacgactaaa
    10321 gaccaaaatg aagattgttc ctgttacgac tgttcaagag gcactggttt atcttcgcaa
    10381 ataaaataac tatgaatgta ttatattcaa ttatattcac gctattaact cataaaaaaa
    10441 cggttgaacc agatagacag atccttgacc agtcttttgg gttcaatcat tttttacata
    10501 aaacatatct aacttgacag cgtaaaaaag atgttataaa agtctagtgg taaaaaggca
    10561 atagagaatt gagtaaactt tagtcgatta tctggaaata gagcatacta aaaacaccta
    10621 gtgaaaattg atttttttca ctagctcatc caagaacttg cgcagataat catgagtcca
    10681 ttccatgact ctattattct ggaaagcctt gcaatagaca agctaacgtt ataacaacta
    10741 aattaaaaac ttgagattga aaaatcccca taaacttatt ttacaaggag gtaaggctat
    10801 ggtaaccatt aaacaagttg ctgaagaagc aggtgtttct agatcaacag tctccaggta
    10861 tatttctcaa aaaggatatg tatctgatga tgcaaggcat aaaatcaaag cagcgatagc
    10921 aaaattacat tacactccaa atgtcttggc gcagtcattg aagacgaaaa aaaatcaact
    10981 agtcggttta ttattaccag acatttccaa tccttttttt ccgaggttag caagaggagc
    11041 agaagaatat ttaaaagaaa aggggtatcg ggttatgcta ggaaatattt cagacagcga
    11101 agctcttgaa gaagaatacg tccatgtcct tcttcaaagc aatgctgctg gcattattac
    11161 tacccatgac tttacaaagc ggtatcctac tcttgctatt ccagttgtag tggtagattg
    11221 tgttgaccaa gagacccagt acggtgtctt ttcagataat agggcagggg gcttattggc
    11281 ggctcagact gtctggcaag caggggcgaa agaagttctg ttaataagag gtccgctgga
    11341 taatgctgaa aacattaatg agcggtttga agctagtttt tcttaccttc aaaaacaaga
    11401 cgtgactatg tatgtgtgtg atagtcagaa ttttgatttt gaaagtattc agctagaagc
    11461 tagttacaac ctcaagtgtt acccaacaat agatagtatt atagcacctt ctgatatcca
    11521 tgctattgct tatattcatg aactgcattc tcaaggtaaa aagattcctc aagatgttca
    11581 aataataggt tatgatgaca ttttaatgag tcaatttatt tatccttctt tatcgactat
    11641 tcatcaatcc tcttatttga tgggccgtta tgccgccgaa ttagtttata ctattgctag
    11701 tcaattaact gtgaaagcaa atcggattaa attgcctgtt cactacgttg agcgagaaac
    11761 aataaggaaa agataagtaa taatattagt ccagatttta gcaggtatga tgaagattta
    11821 ttgggattta ccttctactt taaaagatgt tatctgtcat tactttcatc gctatcagtc
    11881 aaaacgcatt cttatgcaac tcttaacctt aagcttaatg tctttttgat aacatagagg
    11941 aatgttacac gatgatgacg caataaagcc taaatatagt aattgtcgtg attttatagc
    12001 tagtgagtaa tgagatagca agtctctcat ttacttacaa aagtcaaaaa atagtgtata
    12061 atggttgagt tacagataac actgcaaaaa agataacaag tgtccataat tatctaagac
    12121 tataaaggcg atatagacag atataaaaaa gatgacgaat cagttatcac tggacaatta
    12181 accgatttag ttacaactaa tggatttttc agaaaggtgt caaatgaaaa aagaaatttc
    12241 gccagaaatg tacaactata ataaatttcc aggtcccaaa tttattcatt ttgaagagca
    12301 agttaaggct gaaggcattg atttgttact cttagaagat gttaagaacg cttttgatac
    12361 gactagcttt ggtcaacgtt atacagaagt tctcctaaag tatgactata ttgttggcga
    12421 ttggggaaat gaacagcttc gtcttaaagg gttttataag gatagtgatg atatcaagaa
    12481 aacgaatcgc atctcacgtt tagaagatta tattaaagaa ttttgcaatt ttggttgtgc
    12541 ttattttgtt ttagaaaatc ttcatccaca agatattaaa tttgaagagg agcgccaacc
    12601 aagacgaaag aaatcaccta aatcaaaatc aaatcgtcgc aagccaaact attcaaatca
    12661 gcagcccgca acacctaaga gtaaatcgaa gcgggtatca aaagaaaagc aacctgaaaa
    12721 ccaagcgttt accagtcaaa aacgtcgaag taatactaag cataaagaaa agtcaaaacg
    12781 taatcagact agtcaactta ataccaaaat tagtcatttt atcatcagaa agaaagataa
    12841 ataatccatg aaaccatcga tttatagctt aacacgcgat gaactgatcg cgtgggcagt
    12901 tgaacgcggc caaaaacagt ttagagctac tcaaatttgg gattggctct ataaaaaaag
    12961 agttcaatct tttgaggaga tgacgaatat ttctaaagat tttgtttcta ttttaaatga
    13021 tagtttctgt gtcaatcctt taaaacagcg agttgtacaa gagtcagctg atggtacagt
    13081 aaaatattta tttgaactgc ccgatggtat gttaattgaa acagttttaa tgcgtcaaca
    13141 ttatggtcat tctgtttgtg tgacgactca agttggctgt aacattggct gtactttctg
    13201 tgctagtgga ttgatcaaaa agcaacgtga tctaaacagt ggggaaatta cagctcaaat
    13261 catgttagtc caaaaatatt ttgacgatag aaagcaaggt gagcgggtta gccatgttgt
    13321 cgtaatgggc attggtgaac cttttgataa ttacaaaaat gtcatgtgct ttcttcgcgt
    13381 catcaacgat gataatggct tagcaattgg tgcccgtcat attacagtct ctacctcagg
    13441 gttagctcac aagattcggg attttgcaaa cgagggagta caggttaatt tagcagtctc
    13501 gttgcatgca ccaaataatg atttacgttc aagtattatg cgagtaaatc gctcttttcc
    13561 gctggaaaag ctcttttcag ctatagaata ctatattgaa aaaacgaatc gtcgtgtcac
    13621 ttttgaatac attatgctaa atgaagttaa cgatagcatt aagcaagctc aagaattagc
    13681 agacttaact aaaactattc gtaagttatc ttatgttaac ttgattccgt ataatcctgt
    13741 ttcagaacat gatcagtata gtagaagtcc taaagagcga gttctagcgt tttatgatgt
    13801 gctaaagaaa aatggagtta actgtgtggt gcgtcaagag cacggaacag atattgatgc
    13861 agcctgtggc cagttacgtt ctaaaacgat gaaaaaagat cgcgaaaagg ttacagcgac
    13921 aaaataaagc ccaaaaaata tctttgattg acaatgcttg atgacaaaat attcctagtc
    13981 actaaaatga ctaggttttt tatctggcct aaaaatgctc tagaagcaca atccaaaata
    14041 atccaaaact aagataagga ataaaaggta tgcgcttgat gcctaatagt aagcaagcag
    14101 taatacctgc taaactagca agttgaatta gccaaatcaa cgacgttaga tccaatacta
    14161 aagctaagct agcaaggtag aaaaaatcgc ctgctccaat tgaaaaaggt cttaaatgag
    14221 ctaataaacc tagtagcagt aatatcaatg ataaataatt gatcgaataa aacaggagta
    14281 gacttacaaa gctaaaaagc cacaagataa aagggtattc ttgagaacgc caatcaaata
    14341 aactaaataa taaagaaaag agtaacaagt aacagtaact agcactaacc caatgtacca
    14401 tactagccca taagataatt attagactta tctctaagct aaagaagatt ttttggctag
    14461 ttataaaatg gttttggagc tgccgaaaaa cgcgtttggc aaaagttagt tggtcacaaa
    14521 caatgacagt ctgtttactt agctgttctt gaccattatc aggaaaataa agtagtaaac
    14581 agtaaaaaag atgggtcaat aagatgcccg aacatatact aaaaaaagct atcatactta
    14641 tttattcgaa aagaaatcaa atacttgcaa tctttcctta atcattgtag aatatagata
    14701 taaaacgata atgattctaa ttaagtgtct aatcatccaa ttaggattat tccgttattg
    14761 tcgaatagga ttaggtcctt aaccctttct tatgtttatc acgttagggt tagttccccc
    14821 tccattcttg ccctttaagc tgaaaagtaa ggagatgtta ttatgacaaa cacactcgtt
    14881 gaaaatattt atgcttcagt aactcacaat atttctaaaa aagaagcatc aaaaaatgaa
    14941 aaaactaaag ctgttttaaa ccaagctgtc gctgacttat ctgtggctgc atctattgtg
    15001 caccaagtac actggtatat gcgtggtcca ggtttcttgt accttcaccc aaaaatggat
    15061 gaattacttg atagcttgaa tgctaattta gatgaaatga gcgagcgttt gatcactatt
    15121 ggcggagcgc cttattctac cctagctgag ttttctaaac actctaaatt ggacgaagca
    15181 aaaggtactt acgataaaac agttgctcag catttagcaa gattggtcga agtttacctt
    15241 tacctcagca gcctttacca agttggtttg gatattaccg atgaagaagg cgatgctgga
    15301 acaaacgatt tgtttacagc agctaagaca gaggctgaaa aaaccatttg gatgctccaa
    15361 gcagagcgtg gacaaggccc agcactctaa tggattatgc cttaggataa aagaagtcaa
    15421 tgataaaatt ggcttctttt ttatggaatc atcgattcat tttcagaaac atagaaagcg
    15481 attccatact tgtcttgaaa tttgccgtag aatttgctaa aatctactta tatgaaaaca
    15541 ctatatgatg tgcaacaatt gctaaaaaac tttggcattt ttgtttacct tggcaaacgt
    15601 ctctatgata ttgaaatgat gaagattgaa cttcagcgtc tctatgatag cggcttattg
    15661 gataagaggg attacttaaa tgcggagtta attttgcgac gtgagcatag attagaattg
    15721 gaaaaagaag gatagacaaa tgagtcaaaa attactgggg attgatttag gtggtaccac
    15781 cattaaattt ggaattttaa cagcagcagg agaagtccaa gaaaaatggg caattgagac
    15841 taatatttta gaaggaggca aacatattgt ccctgatatc atcgcttcca tcaaacatcg
    15901 cttagacttg tatggtctaa gcagtgctga ttttgtggga attggtatgg gatcaccagg
    15961 agcggttgac cgtgatacta atacagttac tggggcattc aaccttaatt ggaaagaaac
    16021 ccaagaagtc ggttccgttg ttgaaaaaga attgggcatt ccttttgcca ttgacaatga
    16081 tgccaatgtg gctgcccttg gtgaacgttg ggtaggtgct ggtgaaaata acccagatgt
    16141 cgtcttcatg acacttggaa caggtgtcgg tggaggcatt attgctgatg gtaacttgat
    16201 tcatggtgtt gcaggagcag gtggtgaaat cggccacatg attgttgagc cagaaaatgg
    16261 ctttgcttgt acttgtggct cacacggctg tttggaaaca gtagcttcag caacaggagt
    16321 tgtcaaagtg gcacgtttat tggcagaagc ttatgaaggg gattcagcca tcaaagcagc
    16381 tattgacaat ggtgaaggtg ttaccagcaa agatattttt atggcggctg aagcagggga
    16441 ttcctttgct gattctgttg tggaaaaggt tggttactac cttggccttg cttcagcaaa
    16501 tatttccaat atcttgaatc cagactcagt ggttatcggt gggggtgtgt cggcagcagg
    16561 agaatttcta cgctcacgta ttgaaaaata ctttgtgacc ttcactttcc cacaagtgag
    16621 gtattcaact aaaattaaga ttgcagagct tggcaatgat gctggaatta tcggtgcagc
    16681 tagccttgct cgacaattta tcacaaaata ggagggggat atgtctccaa tcacacttat
    16741 cttatggtta cttcttgtcg gcattgttgg ttattataca tggaactatt tctcttttcg
    16801 aaaaatggca aagcaggttg ataacgagac ttttaaagac gtgatgcgtc aaggtcaatt
    16861 gattgattta cgagagccag cggcttttag agctaagcat attttaggag ctcgaaattt
    16921 tccagcgcaa caatttgatg ctgctatcaa aggtcttcgc aaggacaaac ctgttcttat
    16981 ttacgaaaat atgcgtcccc agtaccgtgt gcctgcggtc aaaaaactta aaaaagctgg
    17041 ctttgaagac gtttatgtct taaaagacgg tattgattat tgggatggca aagttaaaca
    17101 aacaacctag ttaagagtaa cgtggagtta aggggaataa aggtagtcac tgtctcaaaa
    17161 accttaaatc ctttttttgc tgtatccaga cttgctgaaa gtctgaaaac atttacaatt
    17221 gattaaaacc agttttttaa aacattttgt gttatactta tctagttaaa atatatttac
    17281 ttagaggaac aaatgactaa cttaagaaac gatatccgta acgtagcgat tattgcccac
    17341 gttgaccacg gaaaaacaac acttgtagat gaattattaa aacaatccca tactcttgat
    17401 gagcgtaaag agcttcaaga gcgtgccatg gattccaatg accttgaaaa agaacgtggg
    17461 attacaatcc ttgcgaaaaa tacggcagta gcctataacg atgttcgtat taacatcatg
    17521 gataccccag gacacgcgga cttcggtggt gaagttgaac gtatcatgaa aatggttgac
    17581 ggggttgttc ttgttgtgga tgcctacgaa ggaacaatgc cccagacgcg tttcgtattg
    17641 aaaaaagcac ttgagcaaaa ccttatcccg atcgttgtgg tgaacaagat tgacaaacct
    17701 tcagctcgtc cagcagaagt tgtagatgaa gtgcttgaat tattcatcga acttggtgcc
    17761 gatgatgagc aattggaatt cccagttgtt tacgcatcag ctattaatgg aacatcatca
    17821 ttatcagatg accctgctga ccaagagcat actatggcac cgatctttga tacgattatt
    17881 gatcatattc cagcgccagt tgataattca gatgagcctt tgcaattcca agtgtcactt
    17941 ttggactaca acgatttcgt aggtcgtatc ggtatcggtc gtgttttccg tggtactgtt
    18001 aaagtgggtg accaagtaac tctttcaaaa cttgatggta ccactaaaaa cttccgtgtt
    18061 acaaaactgt ttggtttctt cggtttggaa cgtcgtgaaa ttcaagaagc taaagcaggt
    18121 gacttgattg ctgtttcagg tatggaagat atctttgttg gagaaaccat tacaccaact
    18181 gactgtgtgg aagctctgcc aattcttcgt attgatgagc caacacttca gatgactttc
    18241 ttggtcaata actctccttt tgcaggtcgt gaaggtaaat ggatcacgtc acgtaaggtt
    18301 gaagaacgtc ttttagcaga attgcaaaca gacgtgtcac ttcgtgttga cccaacagat
    18361 tcgccagata aatggacggt ttcagggcgt ggagaattgc atttatctat cctcattgaa
    18421 accatgcgcc gtgaaggcta tgaacttcaa gtatcacgtc cagaagttat catcaaagaa
    18481 attgatggtg tcaaatgtga accgtttgag cgtgttcaaa ttgatacacc agaagaatat
    18541 cagggtgcaa tcatccagtc tctttcagaa cgtaaagggg atatgcttga tatgcagatg
    18601 gttggtaatg gtcaaacgcg tttgattttc ttgattcctg cacgtggttt gattggttat
    18661 tcaacagagt ttctttcaat gacacgtgga tatggtatca tgaatcatac ttttgatcag
    18721 tatctaccgg ttgttcaagg agaaatcggt ggccgtcatc gtggtgcctt ggtttctatt
    18781 gaaaatggga aagcaacgac atattcaatc atgcgtattg aagaacgtgg aactatcttt
    18841 gtcaacccag gtacagaagt ttacgaaggg atgattgttg gtgaaaactc acgtgataac
    18901 gaccttggtg ttaacattac aacagctaag caaatgacaa atgtccgttc agcgactaaa
    18961 gatcaaactg cagttatcaa gacgcctcgt atcctaacgc ttgaagaatc attagagttc
    19021 ttgaatgacg acgaatacat ggaagtaacg ccagaatcta tccgcttgcg taaacaaatc
    19081 ttgaataaag ctgcgcgtga taaagctaat aaaaagaaaa aatcagccga atagcttttg
    19141 aagttaaact aactaaataa aatagcaaaa agatatttaa gaaaagtcat tttttaaagg
    19201 tctttttgcg tttacaagtt cctatggaat ataaaccaaa ataaaggagg acggaatgtt
    19261 ttaccttatt atggctgtct cgattatatc ttattatcta tacatggctc ctaaaagtgt
    19321 ccgtaacacc cttgggatga ttggtttagt tggcttggtt gctctgctta ttgttttagc
    19381 gggcttgagt tttatcaaaa tcatgcaaac ccctcctgaa ttttttattg ggatgggaat
    19441 ggtggcattg ggctattttg ctttaaaaga tgtgcgtaaa atgaccaaaa aaccgagagt
    19501 taaataaaaa tacttaaaga ttgatgattt tggtttttat acgataaaag gactgatttg
    19561 ttttagacaa tatcagtcct tttttaatag ttcatttttt ctgaaagaaa gcttttagcc
    19621 gattttcatt gagtgtgcaa ctaaaaaaag atgcttggta gtgacagtta agacctctga
    19681 ctagtatttt atcttacttt acttaaaaaa acgtaccaat aatctcacaa atatgggcat
    19741 gatgtttgta tattggaaac ggattctaat tctaaactca agaacggtat ttttaaaatg
    19801 ttgaaaaagc atctaaataa aggtaaaata gaaatcaaat agaatggata gtgtgagctt
    19861 agatgaaagt gataagtaat tttcaaaata aaaaaatatt aatattgggg ttagccaaat
    19921 cgggcgaagc agcagcaaaa ttattgacca aacttggtgc tttagtgact gttaatgata
    19981 gtaaaccatt tgaccaaaat ccagcggcac aagccttgtt ggaagagggg attaaggtca
    20041 tttgtggtag ccacccagta gaattattag atgaggactt tgagtacatg gttaaaaacc
    20101 ctgggattcc ttatgataat cctatggtta aacgcgccct tgcaaaggaa attcccatct
    20161 tgactgaagt agaattggct tatttcgtat ctgaagcgcc tattatcggg attacaggat
    20221 caaacgggaa gacaaccaca acgacaatga ttgccgatgt tttgaatgct ggcgggcaat
    20281 ctgcactctt atctggaaac attggttatc ctgcttcaaa agttgttcaa aaagcaattg
    20341 ctggtgatac tttggtgatg gaattgtcct cttttcaatt agtgggagtg aatgcttttc
    20401 gccctcatat tgctgtcatc actaatttaa tgccgactca cctggactat catggcagtt
    20461 ttgaggatta tgttgctgct aaatggatga ttcaagctca gatgacagaa tcagactacc
    20521 ttattttaaa tgctaatcaa gagatttcag caactctagc taagaccacc aaagcaacag
    20581 tgattccttt ttcaactcaa aaagtggttg atggagctta tctgaaggat ggaatactct
    20641 attttaaaga acaagcgatt atagctgcca ctgacttagg tgtcccaggt agccacaaca
    20701 ttgaaaatgc cctagcaact attgcagttg ccaagttatc tggtattgct gatgatatta
    20761 ttgcccagtg cctttcacat tttggaggcg ttaaacatcg tttgcaacgg gttggtcaaa
    20821 tcaaagatat taccttctac aatgacagta agtcaaccaa tattttagcc actcaaaagg
    20881 ctttatcagg ttttgataac agtcgcttga ttttgattgc tggcggtcta gatcgtggca
    20941 atgaatttga cgatttggtg ccagaccttt taggacttaa gcagatgatt attttgggag
    21001 aatccgcaga gcgtatgaag cgagctgcta acaaagcaga ggtctcttat cttgaagcta
    21061 gaaatgtggc agaagcaaca gagcttgctt ttaagctggc ccaaacaggc gatactatct
    21121 tgcttagccc agccaatgct agctgggata tgtatcctaa ttttgaggtt cgcggggatg
    21181 aatttttggc aacctttgat tgtttaagag gagatgccta atgcctaaga agattttatt
    21241 tacaggtggt ggaactgtag gtcatgtcac cttgaacctc attctcatac caaaatttat
    21301 caaggacggt tgggaagtac attatattgg tgataaaaat ggcattgaac atacagaaat
    21361 tgaaaagtca ggccttgacg tgacctttca tgctatcgcg acaggcaagc ttagacgcta
    21421 tttttcatgg caaaatctag ctgatgtttt taaggttgca cttggcctcc tacagtctct
    21481 ctttattgtt gccaagcttc gccctcaagc ccttttttcc aaaggtggtt ttgtctcagt
    21541 accgccagtt gtggctgcta aattgcttgg taaaccagtc tttattcatg aatcagatcg
    21601 gtcaatggga ctagcaaaca agattgccta caaatttgca actaccatgt ataccacttt
    21661 tgagcaggaa gaccagttgt ctaaagttaa acaccttgga gcggtgacaa aggttttcaa
    21721 agatgccaac caaatgcctg aatcaactca gttagaggcg gtgaaagagt attttagtag
    21781 agacctaaaa accctcttgt ttattggtgg ttcggcaggg gcgcatgtgt ttaatcagtt
    21841 tattagtgat catccagaat tgaagcaacg ttataatatc atcaatatta caggagaccc
    21901 tcaccttaat gaattgagtt ctcatctgta tcgagtagat tatgttaccg atctctacca
    21961 acctttgatg gcgatggctg accttgtagt gacaagaggg ggctctaata cactttttga
    22021 gctactggca atggctaagc tacacctcat cgttcctctt ggtaaagaag ctagccgtgg
    22081 cgatcagtta gaaaatgcca cttattttga gaagaggggc tacgctaaac aattacagga
    22141 acctgattta actttgcata attttgatca ggcaatggct gatttgtttg aacatcaggc
    22201 tgattatgag gctactatgt tggcaactaa ggagattcag tcaccggact tcttttatga
    22261 ccttttgaga gctgatatta gctccgcgat taaggagaag taaatggcaa aagataaaga
    22321 gaaacaaagt gatgacaagc tcgttttgac agagtggcaa aagcgtaaca ttgaattttt
    22381 aaagaaaaag aagcagcaag ctgaggaaga aaaaaaactc aaagagaaat tattgagtga
    22441 taaaaaagcg cagcagcaag ctcaaaatgc ttctgaagca gttgagctta aaactgatga
    22501 gaaaactgat agtcaggaaa ttgagtcaga aacgacgtca aaacctaaaa aacccaaaaa
    22561 agttagacaa cccaaggaaa aaagcgcgac acaaatcgct tttcaaaaat ccttgcctgt
    22621 tcttttgggg gcgctcttac ttatggcggt gtctattttt atgatcactc cttatagcaa
    22681 aaagaaagag ttttctgtaa gaggaaacca tcaaacgaac cttgacgaat taatcaaagc
    22741 tagcaaagtc aaagcatctg actattggtt aacgttgtta acttcgcctg gtcagtatga
    22801 acgaccgatt cttcgtacta ttccatgggt gaaatctgta catctctctt accaatttcc
    22861 taatcacttt ctatttaacg ttattgaatt tgaaatcatc gcttatgcac aagtcgaaaa
    22921 cggttttcag cctattttgg agaatggaaa acgtgtggac aaggtcaggg catcagaact
    22981 accgaaatct ttcttgattc ttaatttaaa agatgagaaa gcgatccaac agttagttaa
    23041 gcaattaacg acattaccta aaaaattagt caagaatatc aagtcagtgt ctcttgcaaa
    23101 ttccaaaacg acagcggatt tactacttat tgaaatgtat gacggtaatg tagttagagt
    23161 accgcagtca caactcacat tgaaacttcc ctattatcaa aaattgaaaa aaaaccttga
    23221 aaatgatagt atagtggata tggaagttgg aatttacact acaacacagg agattgaaaa
    23281 tcaacctgaa gttcctctta cgccagaaca aaacgcagct gataaagaag gagataagcc
    23341 tggtgagcat caggaacaga cagacaatga ttcagaaacg ccagcaaatc agagtagtcc
    23401 tcagcaagca ccaccatccc cagaaacggt cctcgaacag gcccatggct agctaatatc
    23461 taagttgaaa aagcaatgaa aacgttagaa attcaacgat tctaacccat aatgaattgc
    23521 ctaaaaaaaa ttaagtttat ataacaaaaa acgtaaaatg ataacatttt acgttttttt
    23581 atggtataat attttctgaa tgattctgtt ttttagcagt ttttagaata gcaaaagttt
    23641 ggaaagtaag tgaggtcaag tgaatggcta gaaatggctt ttttactggt ttggacattg
    23701 gaacaagctc gataaaagtt ttagtagcag aatttatttc tggtgagatg aacgtcattg
    23761 gtgttagtaa tgttccaagt accggcgtaa aagatggcat aataatcgat atagaggcag
    23821 ctgcgactgc catcaaaact gcggtagaac aagcagaaga aaaagcaggg atgacaattg
    23881 aaaaggttaa tgttgggcta ccggcaaacc ttcttcaaat tgaaccaaca caaggaatga
    23941 ttcctgtccc aagtgagtct aaagagataa aagatgagga tgttgatagc gttgttaaat
    24001 cggctttaac aaaaagtatc acaccagaac gagaggttat ctctttagtt ccagaagagt
    24061 tcattgtgga tggctttcag ggcattcgag atccacgtgg tatgatgggg attagattag
    24121 agatgcgcgg gcttatttat actggaccaa gcaccatttt acataatctg cgtaaaacgg
    24181 tagaaagagc aggcattaaa gttgaaaaca tcattatttc tccgttagct atggctaaaa
    24241 ccattttaaa cgaaggtgag cgcgagtttg gagctactgt aattgatatg ggaggtggac
    24301 agacaactgt cgcttctatg cgagcacaag aattgcagta taccaatata tatgctgaag
    24361 gcggcgaata cattactaaa gatatatcaa aagtattaaa aacgtctttg gctattgcag
    24421 aagcacttaa gtttaatttt ggtcaagcgg agatatcaga agctagtata actgaaacag
    24481 taaaagttga tgtggtaggt agtgaagagc ctgttgaggt aactgaacgt tatttatctg
    24541 aaattatttc agcgcgtatt cgtcatattt tagatcgtgt gaagcaagat ttggaaagag
    24601 gtcgtttact agacttacca ggaggcattg ttttgattgg tggcggtgca atcatgcctg
    24661 gagtggtaga aattgcacaa gaaatctttg gagtaactgt aaagctccat gttccaaatc
    24721 aagtcggtat tagaaatcca atgttttcaa acgttatcag tttggtagaa tatgttggta
    24781 tgatgtctga agtagacgtt ttagcacaaa ctgcagtttc aggagaagaa cttttgcgac
    24841 gcaagcctat cgatttcagt ggtcaagaat cttatttacc agattatgat gattcaagaa
    24901 gaccagaatc gaccattggc tatgaacaac aagcgtcaca aacagcatat gattcacaag
    24961 ttccgagtga tcctaaacaa aaaatttcag aacgtgttcg tggcatattt gggagtatgt
    25021 ttgattaaaa gtaataaagt gaggagataa aatggcgttt tcatttgata ctgcatcaat
    25081 tcaaggtgca attataaaag taattggagt cggcggaggt ggcggaaatg ccattaatcg
    25141 tatgattgat gaaggtgttg ctggtgtcga gttcatcgca gcaaatacag acattcaggc
    25201 attaagctca tcaaaagctg aaacggttat tcaactaggc cctaaattaa ctcgtggact
    25261 tggtgctgga ggacaacctg aagtaggacg taaagctgct gaagaaagcg aagaaatttt
    25321 aacagaagct cttacaggag cggatatggt atttattact gccggtatgg gtggtggctc
    25381 tgggacaggg gctgcaccgg ttattgctcg tatcgctaag agtttgggag ccttgacagt
    25441 agctgttgtt actcgcccgt ttggttttga aggtaacaaa cgtggtaatt ttgctattga
    25501 aggtatcgaa gaactccgtg aacaagttga tactttgtta attatttcaa ataataacct
    25561 tcttgagatt gttgataaaa agacaccttt attagaagca cttagtgaag ctgataatgt
    25621 tttacgtcag ggagttcaag ggataaccga cttaattact agtcctggcc ttatcaatct
    25681 cgattttgcc gacgtgaaaa cagttatggc aaataaaggg aatgccttaa tggggattgg
    25741 gattggttct ggagaagagc gcattgttga ggcggcgcgt aaggcaatct attcacccct
    25801 attagaaacg actattgatg gtgcacaaga cgttattgtg aacgttacag gaggtctcga
    25861 catgacactc acagaagctg aagaagcctc tgaaattgtt gggcaagctg ctggtcaagg
    25921 cgttaacatt tggttaggaa catctattga tgatactatg aaagatgaca tccgtgtgac
    25981 tgttgtagca actggagtgc gccaagaaaa agccgaacaa gtttcaggtt ttcgtcagcc
    26041 taggactttt acccaaacca acgcgcagca agtagcgggt gcacaatatg catcagatca
    26101 agcaaaacag tcggttcaac cagggtttga tcgtcgctca aattttgatt ttgacatggg
    26161 ggagtctcgc gagataccaa gtgcacaaaa ggtaatttct aatcataatc aaaatcaagg
    26221 ttctgctttt ggaaattggg atttgagacg tgataatatt tctcgtccaa cagaaggtga
    26281 attggataac catcttaata tgtcaacgtt ctcagctaac gatgacagtg atgatgaatt
    26341 agaaacgcct ccattcttta aaaaccgtta ataatggatt tactgacaaa taaaaagaaa
    26401 atttttgaga ctatccgctt atctacagag gcagcaaata ggactaatga tagtgtttca
    26461 gttattgctg taacaaaata tgtggatagt acaattgcag gtcagcttat cgaagcagga
    26521 attgagcaca ttgccgaaaa ccgtgttgat aaatttcttg aaaagtatga tgcgttaaag
    26581 tatatgccag taaagtggca tttaatcggt accttacaac gtcgtaaagt caaggaagtt
    26641 atcaattatg ttgattattt tcacgctcta gattctgtga gattagcttt ggaaatcaac
    26701 aagagagctg accatcctgt gaagtgtttt ctacaagtta atatttctaa agaagagagt
    26761 aaacatggtt ttaacatttc tgagattgat gaagcgattg aagaaatagg taagatggag
    26821 aagatacagt tagttggttt aatgactatg gcaccagcaa atgccagtaa agaaagtatt
    26881 ataactattt ttcgacaagc aaatcaatta agaaaaaact tgcagttaaa aaaaagaaag
    26941 aatatgcctt ttacagaatt gagcatgggc atgagtaacg attatccaat tgctattcaa
    27001 gaaggctcaa cttttattcg gattggtaga gctttctttc actaatggag aataagatgg
    27061 cttttaaaga tacatttaac aagatgattt cttattttga cacggatgag gttaacgaag
    27121 ttgaagaaga tgttgcagca tcaactgata acgttattcc aagatcacaa caatcagtca
    27181 gagcaagtag tcatccaaaa caagaaccta gaaacaatca cgtacaacaa gatcatcagg
    27241 cgagatccca agaacagaca aggtcacaaa tgcatccaaa acatggtact tctgaacgct
    27301 attatcagca gtctcagcca aaagaaggcc atgaaatggt tgacagaaga aaacggatga
    27361 gcacttctgg tattgcaaat cgccgtgagc agtatcaaca atcaacttgt tcagatcaga
    27421 caactattgc cttaaaatat cctcgtaaat atgaggatgc tcaagaaatt gtggatcttt
    27481 taatagttaa tgaatgcgtt ttgattgatt ttcagtttat gctagatgct caggctagac
    27541 ggtgtttaga ttttattgat ggtgctagta aagtgctcta tggtagctta caaaaggtcg
    27601 gctcttcaat gtacttactg gctccgtcaa atgtatccgt caatatagaa gaaatgacta
    27661 tcccacatac tacacaagat attggctttg attttgatat gaaaaggcgg taaataaatg
    27721 atattaatac tatctattct tcttcgtctg atcaaagttt acacttattt attgattgct
    27781 tacgcattaa tgtcatggtt tcctggggca tatgattcaa aaattgggcg tttgattagt
    27841 ggtatcgttg aaccaatttt aaaacctttt agagcattta atttacaatt tgccggtctt
    27901 gacttcacta tttttgtcgt cattattagt ttgaattttt tagctcaagt tttggtccgt
    27961 gtgtttattt aatggttagt catagtaaga tttatcagca ttttcaccaa gaagaatatc
    28021 cttttattga tagaatgtct gatatgatta atagagttgg agattactat cttttagaag
    28081 ttactgagtt tttaaatcct agagaagtga tgattttaaa aagtttgatt gctttaacag
    28141 atctaaaaat gttcgtatca acagattact acccaagcga atatggtcgt gtcattattg
    28201 cacctggtta ctatgactta gaacaaagtg attttcaaat agctttagta gagataagtt
    28261 atcaggcaaa gtttaatcag ttgacacata gtcaaatttt aggaacttta attaatgaat
    28321 taggagtaaa gcgaaattta tttggagatg tttttgttga aatgggatat gcccagctca
    28381 tgattaagcg ggagttattg gattattttt taggaacaat tactaaaata gctaaaacta
    28441 gtgtgaaatt aagagaagtt aactttgatc agttaattag gtctattgat aacagccaga
    28501 ccctggatat tctagtttct agttttcgat tagatggtgt agttgctact atcttaaaaa
    28561 aatctcgaac gcaagttata gcattaattg aagcaaataa gattaaggta aactatcgac
    28621 tcgctaataa agcttcagat aatctagtca taggggatat ggtgagtatc agaggtcacg
    28681 ggcgttttac tcttttagca gataatggag tgaccaaaca tggcaaacaa aaaataacac
    28741 taagtaaaat gatacataaa taaggagata caatggcact tacaacgcta gaaattaaag
    28801 ataaaacttt taagacaaaa ttccgaggat actgtgaaga agaagtcaat gaattccttg
    28861 atattgttgt tgatgattac gaagctcttg tacgtaaaaa tcgtgataac gaagcaagaa
    28921 ttaaagatct tgaagaaaaa ttatcttact ttgatgaaat gaaagagtca cttagccagt
    28981 ctgtaatctt agctcaagaa acagctgaaa aagtgaaagc aacggctaat gcggaagcaa
    29041 caaacttggt tagtaaagcg acttatgatg ctcagcattt attagatgaa tctaaagcta
    29101 aagccaatca aatgttgcgt gatgcaactg atgaggctaa gcgagttgcg attgaaacag
    29161 aagaactaaa gcgtcaaaca cgtgtgttcc accaacgttt aatctcatct attgagtcac
    29221 aattaagctt atcaaattca cctgaatggg atgaactgct acaaccgact gcaatctatc
    29281 ttcaaaattc tgacgatgct tttaaggaag tcgtgaagac cgttcttaat gaagacattc
    29341 ctgaatctga tgatagtgcc tcttttgatg caacacgtca gtttactcca gaagagttag
    29401 aagaattgca acgtcgtgtt gatgaaagca ataaggagtt agaggcttac caacttgact
    29461 ctcaatctga ttctacgact gagccagagg taaatctcag tgaaacacaa acgtttaaat
    29521 taaatatcta aataaagaaa aacaagatga tttgcttata atcacagcaa gcgggagatg
    29581 atgagagtct cgtattccct aagtattatc attatcattt tctaaaattt tcgctgaact
    29641 acagtaagcg aggaggtttg ttcaccttac gagcaaagag ggagcggtaa gtcttatgat
    29701 atattatcgc tctgaactaa ggtggtacca cgagctttcg tcctttttga gacgaggctt
    29761 ttttcgttat agtcgcaagt ttgtttaaaa ggagtttgaa ataatgaaat taaaagagac
    29821 acttaatcta ggaaaaacag cctttccaat gcgcgcaggt cttcctaata aagagccaca
    29881 atggcaagca gcttgggaac aagcagagct ttacaaaaaa cgtcaagaat tgaatgcagg
    29941 taagcctgcc tttcatcttc atgatggacc tccatacgct aacggcaata ttcacgttgg
    30001 gcatgccctt aataaaattt caaaagatat cattgtgcgt tctaagtcca tgtctggctt
    30061 tcaagcgcct tatgtacctg gttgggacac acacggcctt ccaatcgaac aagtcttggc
    30121 taagcaagga atcaaacgta aggagatgga tttagcagaa taccttgaga tgtgtcgtca
    30181 atacgcttta agtcaggttg ataaacagcg agatgatttc aaacggttag gtgtttcggc
    30241 agactgggaa aatccttatg tcactttgga cccacagttt gaagctgatc aaattcgtgt
    30301 ttttggagcg atggctgaaa aaggttacat ctatcgtggt gctaaacctg tttattggtc
    30361 atggtcttca gaatcggcct tggcagaagc tgaaattgaa taccatgaca tcgattcaac
    30421 ctctttatac tacgccaata aagttaaaga tggtaaaggt atccttgata ctaatacgta
    30481 tatcgttgtt tggacaacaa caccatttac ggttacagca tcacgcggtt tgactgttgg
    30541 tcctgatatg gattatcttg tggtgaaacc tgctggttca gaccgtcaat atgttgtggc
    30601 agaaggtctt ttggatagcc ttgctggaaa atttggctgg gaatcttttg aaactttagc
    30661 tagccataaa ggagctgatt tagagtacat tgtgacagaa cacccatggg atactgacgt
    30721 agaagaattg gttatccttg gtgaccatgt tacccttgag tcagggacag ggattgtcca
    30781 cacagcacca ggttttggtg aggatgacta caatgttggg acaaaatata aactggaagt
    30841 tgctgtgact gttgatgaac gtggcctaat gacggaaaat gcaggtccag atttccacgg
    30901 acaattttat aacaaggtaa cgccgattgt cattgataaa cttggtgatc ttttattggc
    30961 acaagaagtg atcaatcact cttacccatt tgactggcgg acgaaaaaac caatcatctg
    31021 gcgtgctgta ccgcaatggt ttgcttctgt ttctgatttc cgtcaagata ttttggatga
    31081 aattgaaaaa acaacctttc atccatcatg gggtgaaaca cgcctttaca atatgattcg
    31141 tgatcgtggc gactgggtta tttctcgtca acgtgcttgg ggagttccgc ttcctatctt
    31201 ctatgccgaa gatggcacag ctattatgac taaagaagtg acagatcatg tggctgattt
    31261 gttccaagaa aatggatcaa tcatttggtg gcaaaaagaa gctaaagacc tattaccaga
    31321 gggcttcact catccagggt caccaaatgg cgagtttaca aaagaaactg atatcatgga
    31381 cgtttggttt gactctggtt cttcttggaa tggagtcatg aatactaaag aaaatctttc
    31441 ctatccagcg gatctctact tagaaggctc tgaccagtat cgtggttggt tcaattcatc
    31501 cttaattaca tctgtggctg ttaatgggca tgctccatat aaggctattt tatcgcaagg
    31561 ctttgttctt gatggtaagg gcgaaaaaat gtctaaatca aaaggcaata tcatttctcc
    31621 taatgatgtg gctaaacaat atggtgcaga tattcttcga ctttgggtag cttctgtgga
    31681 taccgataat gatgtccgtg tttctatgga gatccttggt caagtctctg aaacttaccg
    31741 taaaatccgt aacacccttc gcttcttgat tgctaataca tctgatttca accctgctac
    31801 ggatacagta gcttatgcag atttaggagc tgttgataag tacatgacaa ttgtctttaa
    31861 tcagttggta gcaacgatta ctgacgctta tgagcgttat gactttatgg ctatttacaa
    31921 agcagtggtg aactttgtta cggttgattt atcagccttc tatcttgatt ttgctaaaga
    31981 cgttgtctat attgaagctg ccaatagctt agaacgtcgt cgcatgcaga cagtcttcta
    32041 tgatatcttg gttaagatta ccaagttatt gacgccaatc ttgcctcaca ctactgaaga
    32101 aatctggtct tatctagagc atgagtcaga agcatttgtt caattggcag aaatgcctgt
    32161 ggcagaaact ttctcagctc aagaggatat tttagaagct tggtctgctt tcatgacttt
    32221 gcgtacccaa gctcaaaaag ctttggaaga agcgcgaaat gctaagatta tcggtaaatc
    32281 attggaagcc catttgacca tctacgctag cgaagaagtg aaaaccttat tgactgcttt
    32341 agacagcgat attgctttgc ttttgatcgt gtctcaatta accattgctg acttggcaga
    32401 tgcgcctgcg gatgcagtgg catttgaagg tattgccttt atggtagaac atgccatagg
    32461 tgaagtttgt gagcgttcac gccgcatcga cccaactact cgcatgcgtt cttacaatgc
    32521 atttgtctgt gatcacagcg ctaaaatcat tgaagaaaat ttcccagaag ctgtggctga
    32581 agggtttgaa gagagtgaca aataagtctt atcaagactt gaagtgacac tgagtaagaa
    32641 gacaaccatc gggtcttagg gcctgatggt tttttagtag agctgattac gtccattagc
    32701 cagctttaac gagagacaaa gtaggagaaa tttagagtac ttttttaatt tcttttaaga
    32761 aaattgctgg cttcatataa ggactattaa gatagagttc acctttcgct aataaaaaaa
    32821 cttagctctt ttagaagggc taagttttgt ctgaatagct ggctgctgtt tatacagaag
    32881 tttgaaatga aatttcaata aggttattcg tgtgaagtgt ttttgattgt ccaggaataa
    32941 caattttagg atcaatttta cgttttaaaa aaaattcgcg aatgatatca agttcatcct
    33001 ccttgatggc acggtattta tttgaaataa gtagttcgta atgttttggt gcttgggtaa
    33061 aaatgacatc tgtatttcct gctgagtata cttcgactaa ataggcatcg gtgtttttta
    33121 gctgatttct gatgagttct gggtgactgc tagtggtatt gatgagtctc ataaatgtcc
    33181 tccttagtat tcctgtacct attatagcac taatttaaag ccttagttag tagaatgatg
    33241 ctttttttgc cattccttga ctccccattg atggctctct cgttttaatt tagcaattgc
    33301 ctcgatagga gaaaaccaac ttaagttatt aaaatcttct aagggcttag aaacggcttg
    33361 aaatgcggtt acttcataaa gataggcagg atggtagaag tgggtatcac gatggcgaga
    33421 gtagaaatat tcatcagcct gaccgtaata tgaaccaata gtagcagaaa aaccaagttc
    33481 ttcaatcagt tcacgctcta gggcctgaag ctgaccttca cctgcttcaa tttcaccacc
    33541 aggtaaaaac caggaaccat taggagcttg aacaagaata atttttgttt gttcgtgatt
    33601 gggaatgata gcatagacac cgtaacgtgt gacatagtct ttatgtgcat ttttatgtcc
    33661 aaatgttgga atcatcattt tatttacctt tcctttttct tcattatact aaatttttgc
    33721 taattattct tatcaatttg tttagtttaa taaaaaattg atagaaaaag agagagtctc
    33781 cttatagaaa ctctcttagc taacgttaat ctagagactc ttcgttaaga aaagaatctc
    33841 cctctttaac agctttaatc gtgatgtttt cactgtttgt catcagtgca cgtaactgtt
    33901 tttcagttgg gtgttctaaa taatagtctg taatggcatc ttcgatataa tcttggatag
    33961 tacgacggag cggccgagcg cccattttag gatcatagcc taaatctact aatttttctt
    34021 tgaccttttg tgtcacatca agatgaatcc cattatagcc taagcgctca ttaacatctt
    34081 ccagcattaa atcaacgata tgcagcaaat gctctttaga taaagctttg aattcaataa
    34141 taccatcgaa acgattcata aactctgggc tgaagaagtt gcttaattca ccaaggacag
    34201 aacttgtccg tccttctcta gcagcaccaa atccgacaga agcttcgctt ttacctgttc
    34261 cggcattaga ggtcatgata ataatggtgt ccttgaagct gactgttcgc ccttggccgt
    34321 ctgttaagcg accgtcatca agaacttgta agaacatgtg catgacgtca ggatgggctt
    34381 tttccacctc atctaagaga ataagggaat aaggattgcg acgaacttgt tcggttagct
    34441 gtccagcttc ttcatagccg acataacctg gaggagcccc gactaatttg gcgacagcgt
    34501 gtttttccat gtattcggac atgtcaaagc gaatcatatt gtttgtcgaa ccaaagagtt
    34561 caatggctag ttgtttagac aattcagttt taccaacccc agtcggtcca acgaataaga
    34621 aagaaccaat agggcgattt ggagttccta atcccacacg gttacgacga atagccttag
    34681 cgattttatc aacagcatcg tcttgcccga tcacgtgtgc tttcagatca ttggctaagt
    34741 ttacgagttg agactgttcc ttttctttta agtccccaac tggaatatta gttttttgct
    34801 ctacaatagc ttcaatggtt ttttcagtaa tgatgggaat atcttgctca tcgacttttt
    34861 gagcctgcat ttctttgtat tttgtaattt gatcgcggaa ataagctgcg cgttcatagt
    34921 cttcgtctcg agtagcttgc gccttgagat tctcagcttc aataagacgt ttgtcaattt
    34981 ctttaggatc aacaaagttg agggttagat tcattttgga accagcttcg tccagaaggt
    35041 caatagcctt atcaggaaga aaacggtctt gaatatagcg gttagataaa tgagcggcag
    35101 cttcaatagc ggctgggcta tatttgacat gatgatagtc ttcgtatttc ggttggatac
    35161 cttttaaaat cgtgatggtt tcctcaacag aaggttcatc aactttaacg ggttgcatac
    35221 gtcgttctaa ggcagcgtct ttttcaataa tacggtattc atttaatgta gtagcaccaa
    35281 cgagttgcaa ctcaccacgg gccaaggctg gttttaaaat attaccagca tccatattgc
    35341 cgtctcctgc agaaccagca ccgacaatct catgaatttc atcaataaag agaatcacat
    35401 ccttgcgatt gcgaatttct tccattaatt tttgcatgcg ctcttcaaac tgaccacgga
    35461 tacctgttcc ctgaacgagg ctaaccacat caagacgaat cacttgcttg ccttggagtt
    35521 tttgaggaac agtaccatca ataatttttt gagccaaacc ttctacaaca gcagttttac
    35581 caactccagg ctcaccaatt agcacaggat tatttttagt acggcggttg aggatctcga
    35641 taacgcgtgt aatctcttcg tcacgaccaa taacaggatc aatattacca tttcttgcaa
    35701 tatctgtgac attaatccca aactcttcta ataagccctt tgcttgctga tttggtgttt
    35761 gtggctgagc aggtcgttgt ccgttgtagt taccaccata gcgtcctccg ccatttccat
    35821 tttgccctgc ctgagtaggt ggggtatttg gaagattacc aaaagctcta aaattattca
    35881 aatcaccaaa aaagtcatca aagaaaggac ttgtggatct atcttgtgct ctatatcctg
    35941 gggttaggcc atttaaaata gaattggcag gatcggattt catgatttga taacaatttt
    36001 gacagagatc aacctgtctt tgttttccat taacacttgt ataaagatga atagtagatt
    36061 cgtttaaatt acaattttga cacagcataa tatacctccg agggtttatc taaaagtcaa
    36121 agtcatttag tcaaaaatgg tcaaacttta tattcatatt atagcaccac ggcttgggaa
    36181 atcaagtaaa aagtttatcg ctttagcgtt agcttttaga gagtaacatg acagagtaac
    36241 tttattaagt ttccaatgag caaatgttta aaatcattga aaagagtaaa aaaagtaaaa
    36301 tatcaataaa tatattactt tccttgttag tttcccttgt tttgtgttaa aataagaggg
    36361 ataaaaaacg aataggagaa acgaaatgga atcacatttg gtgagaatca tcaatcgttt
    36421 ggagttgatg gtgacagatg gcggtaatct caagcgaaat tttgaacgcg atggtgttgt
    36481 tgttgcagaa gttgcctttt caaatgatcc tgaaaatgga cctgttttca cattgcgtga
    36541 tgttgaagcg cgtgagtcat attcctttga tagcattgac ttgattgcaa tggaaatcta
    36601 cgatttatta tattaagctt gacatagtaa agagacttgc ctgaggcagg tttttttatt
    36661 gtcaaaaagt attgtattaa tattcatcag atggtataat tatctttatt gtaatgaacc
    36721 taggacttat gaggagatat aaatggattt gtcatttttg cccaaatact gggcctactt
    36781 taactacggt gtacttgtca ccattatgat ttcagtcagc gttgtctttt ttggaaccct
    36841 tattggtgtc ttggtaaccc tgattaagcg tagtcatgtg aagccgttga cctgggtcgt
    36901 taatctttac gtttggatct ttcggggaac acctatggtg gttcaaatca tgattgcctt
    36961 tgcttggatg cattttaaca atatgcctac tattggtttt ggggttttag acttggactt
    37021 ttcaagacta cttcctggaa ttattatcat ttcattgaat agcggtgctt atatttcaga
    37081 aattgttaga gcaggtattg aggctgtacc aaaagggcaa ttagaagcag cttattcact
    37141 aggtattcgt cctcaaaatg ccatgcgtta tgtgattttg cctcaggcct ttaaaaatat
    37201 tttgccagcc ttaggaaatg aatttattac cattattaag gatagtgctt ttttacaaac
    37261 cattggagtg atggaacttt ggaatggtgc ccaatcagtg gtaacggcta cttattctcc
    37321 aatttcccct ttactggtgg ctgcttttta ctacttaatg gtcacaacag tgatggcaca
    37381 gttattggca gtcttagaac gtcacatggc gcaaggaggt aatcattgat gactgaggcc
    37441 attatttcaa ttaaagactt gcacaagtat tatgggcaca atgaagtgct taagggaatt
    37501 gatttagaca ttatgccagg agaggttgtg gtgattattg gcccgtctgg ttctggaaaa
    37561 tcgaccttac ttcgaaccat gaatcttttg gaagtaccaa ctaagggaca gattaggttt
    37621 gaggggattg atattaccga taagaagaac gatattttca gcatgcgtga aaaaatgggg
    37681 atggtttttc agcagtttaa cctctttccc aatatgactg ttttagaaaa tatcacttta
    37741 tcgccaatca aaactaaggg aatggctaaa gcagaggctg acaaaacagc cttgagcttg
    37801 ttggacaaag ttggattatc agaaaaagcc aaggcttatc ctgctagtct ttctggtggg
    37861 caacagcagc ggattgcgat tgcgcgtgga ctggctatgg atccagatgt tttactcttt
    37921 gatgaaccaa cttcagctct agacccagaa atggtgggtg aggtcttggc tgtcatgcaa
    37981 gatttggcta aatctgggat gactatggtt attgtgactc atgaaatggg ctttgctaaa
    38041 gaagtcgcag atcgtgtgat ttttatggat ggtggcgtta ttgtggaaga aggaagtcct
    38101 aaccaacttt ttgatctgac taaagaagaa cgtacaaaag attttttgag tagagtatta
    38161 taaatctgtt ctatgaatta taaaaggaag tcctaaatca tttaggactt ccttttataa
    38221 tttgctaagg cattttatag gagattactt ttctttttgt taaaataaaa agaaatagtt
    38281 acattatttg catagaagaa agggatctgt tatggtttca gtgatgtggt ttcgtagaga
    38341 tttaaggatt gatgatcaaa aagctttagc tcatgctatt gctagtcaat cgccaacctt
    38401 atgtgtgttt caatttaaca aggagcaatt aaacctgcta catagtcgga atcaatctag
    38461 ttttattact agcgttttgg cttttagaaa gttattaaaa tgtgaaagta ttgacttata
    38521 tctaatgtat ggagacttaa tgacctgttt tgagcaatta ttgacacaat taaaagactg
    38581 gacagatgtg tattttaact atgatgaatc tggatatggt cgtttacgtg atcaaaaagc
    38641 agcacaattt ttcaaaaaaa atgggattgc tgttcatacc taccaagatc actatttaca
    38701 tggtagtcaa gagatcatta accaatcagg tcagccttat aaagttttta cgccctacta
    38761 taggatttgg caaaattatc cgaaagagac tcctattaaa gtagaactat cgcaaggcag
    38821 gtggttaaat cttgagacac cagatgatgt tttaaggact gttgagagct ttaaagatga
    38881 aaaatatcag gatgttgcaa cttttgatga agcgtcaaaa caactaaatc gatttattca
    38941 agaccaatta gcagcttatc acgctaatcg agattttcca gcgcagctag ggacgagtcg
    39001 gttgtctccc tttttaagaa taggagctat tggcattcgc acggtatatc acgctgtgcg
    39061 tcaagcacca aatagtctag ggcaagctac ttttttaaaa gaattagctt ggagagactt
    39121 ttacaatatg gtctatgtgg cttatcctga tcagaaaact cagcctatcc aaaaagcctt
    39181 ttctcaaatc gaatgggtta ataatcctga ctggtttcag ttgtggaaag aaggtaaaac
    39241 gggttaccct attgttgatg ctgccatgct tcagttacaa aagacaggat ggatgcataa
    39301 tcgtttacga atgatagtag cttctttttt aactaaagat cttttatgtg attggcgttt
    39361 aggagagcag tattttcaac aacaactaat tgattatgat gctgccagta atatcggagg
    39421 atggcagtgg gctgcttcca ctggaacaga tgctgttcct tattttagaa tatttaatcc
    39481 tgttactcaa ggtaagcgtt ttgatcccaa aggcgagttt attaaagcgt atttgcctca
    39541 actagaacac gttccagaga agtatctcca cgaaccgtgg aagatgccaa aataccttca
    39601 agagagtgta tcctgtatta ttggcacaga ctatcctcaa ccaattgtcg atcatgctaa
    39661 acaacgtgaa caagctattg caaagtatga gtgggcaaaa gaaaaagcaa aaatagaatg
    39721 actgttctca ttataagagt ttaaacaaaa agttatcatg aattaagatt atttaattta
    39781 aaaaataagt tgactttatt tagattattt gatactattc agttgtctcc cttagagaaa
    39841 gcgatttctt gttttggagc tgatttttac catttggtct tagaatagga tgagtaatat
    39901 gacttacaac gaggtatatc aagaatggtt gcacaataat gatcttagtg atgatattaa
    39961 agcagattta gcagccataa aagacaatga ggctgagatt caagatcgtt tttacaaaac
    40021 acttgaattt ggaacagcag ggctaagagg aaaacttgga gcaggcacca atcgcatgaa
    40081 tacctatatg gttggtaagg cagcacaagc tttagctaat actattattg atcatggacc
    40141 tgaagcggtt aaaaagggca ttgcggttag ttatgatgtt cgctatcaat ctagaacatt
    40201 tgcagaatta acatgctcta ttatggcagc taacggtatt aaggcgtacc tttataaagg
    40261 gattcggcca acaccaatgt gttcgtacgc tattcgtgct ttgggatgta tctctggtgt
    40321 tatgattaca gctagtcaca atccccaagc ttacaatggt tataaagctt attggcaaga
    40381 aggttctcaa attttggatg acattgcgga tcaaattgca caacacatgg ctgcactaac
    40441 tcagtatgag gaaatcaaac aaatgccttt tgaaaaggct ctggacagtg gacttgttac
    40501 ttatattgat gagagtattg aagaagcata taaaaaagaa gtgcttggtt taacgattaa
    40561 tgatactgac attgataagt cagtccgagt agtctatacc cctttaaatg gtgttgggaa
    40621 tctaccagtg cgtgaggttt taagacgccg cggttttgaa aatgtttatg tggtacctga
    40681 gcaggaaatg cccgatcctg attttacaac agttggctat cctaatcccg aagtccctaa
    40741 aacttttgca tattcagaaa aattaggtaa ggcagttgat gctgatattt tgattgcaac
    40801 tgatccagat tgtgaccgtg tggctttaga agttaaaaat gcagtcggtg actatgtttt
    40861 tctcaatggc aataaaatcg gagcgctttt atcttactat atcttttcac aacgatttga
    40921 cttaggcaat ttaccggcta atcctgtttt agtgaaatcc attgtaacag gagacttgtc
    40981 acgggctatt gctagccatt atggtattga aaccgttgaa acattgactg gttttaagaa
    41041 tatttgtggc aaggcaaacg aatatgatgt gacgaaacaa aaaaactacc tgtttggtta
    41101 tgaagaaagt attggttttt gctatggcac ttttgttcgt gacaaagacg ctgttagcgc
    41161 ctctatgatg attgtagaaa tggcagctta ctacaagaaa aaagggcaga atttactaga
    41221 tgttttgcag actatttatg cgacatttgg gtattataat gaacgtcaaa ttgccttgga
    41281 gcttgagggg atagaaggac aaaaacgcat tgcgaggata atggaagatt tcagacagac
    41341 accaatagct agtgttgcag agatggcgtt agacaagaca attgatttta ttgatggcta
    41401 tcaagatttt ccaaagcaaa actgtctcaa attttatttg gatgatggtt cttggtatgc
    41461 acttagacca tcaggaacag agcctaaaat aaaattttat ttatatacta ttggccaaac
    41521 acaagaaaat agtgcaacaa aattagatgc tattgaagca gcgtgtcgca caaaaataaa
    41581 tcaagttaat taaacatcaa aaatggataa cacttttaca ctatttttcc atataaacaa
    41641 ctacaaaagg aggtgagact tttaggcacc ttctttttct tgtaggtgcc actaatcaat
    41701 ttaatcgact caaaccaata ctaaaaaata agtaagagta taaagaacag gcatctattt
    41761 ttttgttata atagaaaaat gaaattaaag ggagatgtca atgacagaac taattgatgg
    41821 taaagcctta gctcaaaaga tgcaacaaga gttagcagct aaagtcaaca atctaaaaca
    41881 aaaaaaagga attgtaccag gcttagccgt tattcttgta ggtgatgatc ctgctagtca
    41941 ggtgtatgtc cgtaataaag agcgtgcagc tcttactgta ggttttaaaa gtgagaccgt
    42001 tagattatca gaattcattt gtcaagaaga gcttattgca gtaatcgaac gttacaatgc
    42061 agataacact attcatggta ttttagtgca gctacccctg ccaaatcata ttaatgataa
    42121 aaaaattatt ctcgccattg atcccaaaaa agatgtggac ggttttcacc cgatgaatac
    42181 aggtcacctt tggtcaggac gtcccttaat ggttccttgt actccatcag ggattatgga
    42241 attgcttcga gaatataatg ttaaccttga aggtaaacat gccgtcatta ttggcagatc
    42301 gaatatcgtt ggaaaaccaa tggcacagct cttactagac aaaaatgcaa cagtcacgtt
    42361 gacacattca agaacacgtc aattagaaga agtatgtcgc tgtgcagatg tgttgattgt
    42421 ggcaatcgga caaggtcatt tcataacaaa acaatatata aaagatggtg cgatagtgat
    42481 tgatgtggga atgaaccgtg atgataatgg caagctaatt ggagatgtgg cctttgatga
    42541 ggtggcagaa gttgcagcga aaatcacccc tgtaccagga ggtgtcggtc ctatgacgat
    42601 tgctatgttg ctagagcaaa cttatcaatc tgccctccgt agtactcata aatagttata
    42661 attagacaat tcaacataag agaatataag aagtcagcaa tggcttcctt ttttgttttt
    42721 ctgctcacta tttatccaga aaaatggtat aattgcatta gtatgcaaag ggactatgtc
    42781 aggtccaact aagtgaaagg tggcttgatg gcagattatt taaccgtcac tcatttgacg
    42841 aaatatttaa aattaaaatt tgaccgtgac ccttatttgg aacgggttta tctgactggt
    42901 caagtgtcca attttcgaaa acgaccaact catcaatatt tttccttaaa agatgaaagt
    42961 gctgtgattc aagccaccat gtgggcagga gtctataaaa aactaggatt cgacctagaa
    43021 gaaggcatga aaattaatgt aattgggcga gtccaacttt atgaacctag tggctcttac
    43081 tctatcgtga ttgaaaaggc agagccagat ggtataggtg ccttggcttt gcagtttgaa
    43141 caattaaaga aaaaattaac ggcagaaggt tattttgagc aaaaacacaa gcagcccttg
    43201 ccacagtttg tatcaaaaat tggggtcatt acaagtccta gtggtgctgt gattcgagat
    43261 attatcacaa ccgtttcacg gcgttttcca ggggttgaga ttttattatt cccaactaaa
    43321 gtacaaggtg atggagccgc ccaagaagta gtggctaata ttcgaagagc caatcaaaga
    43381 gaggatttgg acttgctcat tgtcggccgt ggaggtggct cgatagaaga cctttgggcc
    43441 ttcaacgagg aaatagtggt tcaggctatc tttgaatcgc aacttccagt gatttcgagt
    43501 gtgggtcatg aaacagacac gactttagcg gattttgtgg cagatcgcag agcagccaca
    43561 ccaacagcag cagcagagtt agcaacgcct attacaaaaa cagatcttat gtcttggata
    43621 gtagagcggc aaaatcgttc ctatcaggcc tgcttgaggc ggattaagca acggcaagag
    43681 tgggtggata aactctcgca atctgttatt tttaggcaac cagaacgatt atatgatgcc
    43741 tacctgcaaa aaattgatcg ccttagcatg accctgatga atacgatgaa agatcgtctg
    43801 agttccgcca aagaaaacaa ggttcagttg gaccattcct tggccaatag tcaattacag
    43861 acaaaaatcg agcgatacca agaccgtgtt gctaccgcta agcgtttact gatggctaat
    43921 atggctagtc aatatgatag tcagctggct cgctttgaaa aagcacagga tgctttgcta
    43981 tcactggatg ccagccgaat tatcgcccgt ggttatgcaa tgattgaaaa aaatcaagca
    44041 ctggtagcct ctgtaagtca gataacaaag ggtgatcagt taaccattaa gatgcgtgat
    44101 ggacaattag atgtagaggt aaaagatgtc aaaaacgaaa acatttgaag aaaatttaca
    44161 agatttagag actattgtga acaaacttga aaatggggat gtccctttgg aagaagctat
    44221 ttcagaattt caaaaaggaa tgcttctctc aaaagaactt caaaagacct tacaagcggc
    44281 agaaaaaaca ctcgtcaaag tgatgcaagc tgatggcaca gaagtagata tggatgatta
    44341 atggacaaat tagctagaat tgacgaagcc attcgtcgct actataagac gactagtaac
    44401 ggtgtatctg aagagttgat tgatgctatc ttgtattctg ttgacagtgg tggcaagcgc
    44461 attcgcccac ttatcttatt agagatgatt gagggatttg gggtatcgtt acagaatgct
    44521 cattttgatt tggctgcagc ccttgaaatg attcatacag gaagtctgat tcacgatgat
    44581 ttgccagcca tggataatga tgattaccga cgtggtagac tgaccaatca caaacaattt
    44641 ggagaggcta ctgctatttt ggcgggagat agcttatttt tagacccctt tgggttaata
    44701 gctcaagctg aattaaatag cgaggttaaa gtagccttaa tccaagaact ttccctagct
    44761 tcaggaactt ttggcatggt tggtggtcag atgctagata tgaaagggga aaatcaagct
    44821 ttgagtctcc ctcagttgtc actgattcac ctcaataaaa ccggaaaatt attaactttt
    44881 ccttttaaag cagcagctct tgtaacagaa caggctatta ctgttcgtca acaactagag
    44941 caggcgggaa tgctcatcgg gcacgccttt cagattaggg atgatatttt agacgtgaca
    45001 gctagctttg aagatcttgg aaaaacgcct aaaaaggatt tatttgcaga aaaagctact
    45061 tacccaagtt tattggggtt agaagcctcc taccaactgt tgacagagag tttagatcag
    45121 gctttgacga tttttcagac actcgaaagc gatgtaggct ttaagcctca aataattaca
    45181 aaactgatag aagggttacg acttaatgcc taaagaaaga gtagatgtgt tagcctataa
    45241 gcaaggatta tttgagacca gagagcaagc taagcgtggt gttatggcag gcttagtggt
    45301 ctctgtgatt aatggccaac gctatgacaa gccaggtgac aaaattgacg atgggactga
    45361 gttaaaactt aaaggtgaaa aactcaaata cgtcagtcgt ggtggattaa aactggaaaa
    45421 ggggctgcac gtttttggtg tatcagttgc taatcaaatt gggattgata ttggcgcttc
    45481 aacaggtggc tttaccgatg ttatgttaca agatggggcc aaactagtct atgccgtcga
    45541 cgttgggact aaccagttgg tatggaaact cagacaagat ccacgagtaa gaagtatgga
    45601 acagtataac tttcgttatg ctcagccaga ggactttaat gagggacagc ctgtattggc
    45661 cagtattgat gtgtccttta tttctctcag cttgattttg ccagccctgc ataacgtttt
    45721 gtcagatcag ggacaggtta ttgctctcat taaaccgcaa tttgaagctg ggcgcgagca
    45781 gattggtaaa aaaggcatcg tcaaggacaa acagattcat gaaaaagtga ttcaaaaggt
    45841 catggatttt gcctcaggtt acggatttac agttaaggga cttgattttt cccctattca
    45901 gggtggtcat ggcaatatcg aatttttagc tcatcttgct aagtcacaga cacctgaaac
    45961 gttagccccg catttgattc aggaagttgt tgccaaggca cataaggagt ttgagaaaca
    46021 tgaaaaagag tgaacgactt gaattaatca aaaaaatggt tttgacgcat ccaattgaga
    46081 cgcaacatga cctcttaaga ttattggcag agcatgggtt agaattaacc caggctacta
    46141 tttcaagaga catgaatgaa attggtatag taaagattcc ttctggcagt ggacgttaca
    46201 tctatggtct ttctcaagat agtggaaaaa agatcgttca aggacctaga tcgataaaga
    46261 gcactatttt agctgtatct gacaaaacaa aaggtttaga acaacacctc tatttaaaag
    46321 tcgtacctgg caatagtaaa ttaatcaaac gttatttatt agcagatttt tcaaaagcta
    46381 tttttagtct tattgctgat gatgatagtt tattgttaat tgcaaagtct ccttcagaag
    46441 cagatatgat acgccaagaa attttgcttt ggatgcaggg tataacctag aaaaaaatag
    46501 gggagaaagt gatgttatta gaaatttcta ttaaaaattt tgctattatt gatgaaattt
    46561 ccctaaattt tgaaaatggt atgacggttt tgacgggtga aactggagca ggaaagtcta
    46621 ttatcattga tgctatgaat atgatgcttg gtgcgcgtgc tagtacagaa gtgattcgtc
    46681 gtggagctaa taaagcagaa attgaggggt tcttttcggt agatgctacc ccagaactgg
    46741 ttgcgtgtct ggaatcatca ggcattgcta tggaagaaga actgattatt cgccgagata
    46801 tctttgccaa tggcagaagc gtgagccgca ttaatggtca gatggttaac ctagccacct
    46861 taaaacaggt cggacagttt ttggtagata ttcatgggca acatgaccaa gaagaattaa
    46921 tgcgaccaca gctccaccag caaattttgg acgcttttgg tgataaggct tttgagcaat
    46981 tgaaagagaa ctatcagctt atttttgatc gttataaaag cttgcgtcgc caggttattg
    47041 acaaacaaaa aaatgaaaag gaacacaaag atcgtattga tatgttggcc tttcagatag
    47101 cagaaattga agctgctgcc ttgagtcgag gtgaggacga ccggttaaat caagaacgtg
    47161 atcgcttaat gaaccacaaa caaattgctg ataccctgac caatgcctac gtcatgctag
    47221 ataatgacga tttttcaagt ctatccaata ttcgctctag catgaatgac ttactatcaa
    47281 ttgagcagtt tgattcagag tacaaaggga tgtcgacttc gatttctgaa gcctattata
    47341 ttcttgaaga agtgagcaag caattatcag ataccattga ccaactggat tttgatggtg
    47401 ggcgattaca ggaaattgaa tttcgcttgg atacactcaa tagcttaacc cgtaaatacg
    47461 gtggtaatgt gaatgatgtg cttgactact acgataatat tatcaaagaa taccagctat
    47521 taacaggaga cgacttgtct tcaggggatc tagaatcaga attgaaagcc ttagaaaaac
    47581 aattggttgc tgcagccact aacttgagtg aacgccgcca tcaattggca gagcaattag
    47641 aagctgagat taaagctgaa cttaaggaac tttatatgga aaaagcagat ttcaaagttc
    47701 actttaccac atcaaaattc aatcgtgatg gtaatgaaag cttggaattt tacatctcta
    47761 ctaatccagg cgaaggattt aagccccttg tcaaggtggc ttctggagga gagttatcac
    47821 gccttatgtt agccatcaag gctgctattt ctagaaaaga agataagacg agtattgttt
    47881 ttgatgaagt agatacaggt gtttctggtc gcgttgcgca agccattgcc caaaaaattt
    47941 ataaaattgg gcgacatggg caagttctcg ctatttcaca cttacctcaa gttattgcta
    48001 ttgctgatta tcagtatttt atttctaaag aaagtaaaga agagtccacc gtttctaagg
    48061 taaggttatt aactcctgaa gaacgtgtgg aagaaattgc tagcatgatt gcaggaacag
    48121 atatgacaca agctgctctt acgcaggctc gtgaactact tgccaaacat taagattgtg
    48181 tttggtattt gatattttca taattagatg acattgattt tttaggtgct aaaataatca
    48241 ttgtgctaga ccatttttcc tctgttaatc tggcttggtt tgccttgaca aacctctgag
    48301 aaatagtaga atagataaga gaattttaag ctgaggggat agaaatgact agtaaaaaag
    48361 cgtgtttatc aagcatcatt gtgttagcaa gtttaacgtg tggaaatgat actgttagtg
    48421 ccaatcatct ctcagcaact ggagataagt ttgatgattg ctcaacactt gttgaaaaag
    48481 atgtggcccc taaagatgaa cttgagatgt tagcatggtc ctcgtctcaa acaactgatg
    48541 atgctgacag agactatgaa gattttctcg atgatgattc ttttatttct caaaatgaaa
    48601 ctgataagat gtttgagaat ttaactgatg ataggttatt aaataaatta gatgaattag
    48661 atgaattaga tgaattagat gaagaagata caattgagcc agagcaaaat gtaataatgc
    48721 ctagtgacga tgagctattt gatttaactg atgctgttga gacacgcctt actgtttcta
    48781 gtgctcccca tttagaggct gaattgccga aaccacattt gaggagccta tcagatacag
    48841 cactgcggtc tggtgaaatt agaggacatt tagataacaa actggacgct ttgtctgtaa
    48901 cagctacaaa gttagcatta acgatggctc aaaaatttga tttgacaacg catgtctatt
    48961 ctataggtga aagctttagt gaagtattag ctgctcatta tgaagacaga aaagcagaat
    49021 cagctttttc taagaaaaag agatttcacc ttcctattgc tactccagat gttgttatag
    49081 aggagttaag gcgcctagtc tcttctattg gaagttcaaa agaagatgtt tcagttcctt
    49141 ataatcggaa gctaggtatg gtagttgcaa aaagaaaaat agccctgcca caaacgggag
    49201 aggagttctc ttattatcca gctttacttg gtttaatgat attaggatta acgccgatta
    49261 tgataccaaa gaagataaat aattaggtaa taagttattg tagttgtaaa agacggggca
    49321 aatgttcaag cgtgaaaagg ttgacttttg cctcgttttg tatctcgtta ttgctaaggc
    49381 attttcttcg agcagctagt gctcgccata cctatctacc gagtgattat tcaatagcac
    49441 taccagtttt gctttattta gtgaggagtg ttagaataaa gaggtgagaa actagtttag
    49501 aatggaaaaa tacatgggaa ctataaaaat tgttacagat tcatcaataa ctattgaacc
    49561 agaattaatt aaagctttag atattactgt agtgccttta tctgtcatga ttgatagcaa
    49621 attatattct gataatgatt taaaagaaga aggtcatttt ttgagtctta tgaaggctag
    49681 caaatccctt cccaaaacca gtcagccacc ggttggtctc tttgctgaaa cttacgaaaa
    49741 tttggtcaaa aaaggagtaa ctgacattgt tgctattcac ctctcaccag ctttatcagg
    49801 tactattgaa gcttcccgtc agggggctga aatcgctgag gcccctgtta cagttttaga
    49861 ttcaggattt actgatcaag ccatgaaatt tcaggtcgtt gaggcagcaa agatggcaaa
    49921 agcgggtgct agtttgaatg agattttggc tgctgttcaa gctatcaaat caaaaacaga
    49981 gctctacatt ggtgtatcta ccttagaaaa tttagtaaaa ggaggtcgta ttggtcgtgt
    50041 gacgggtgtt ttgagctcgc tacttaatgt caaagttgtt atggcactta aaaatgatga
    50101 gttaaaaacg cttgtcaaag gtcgaggtaa taaaacattt acgaaatggt tagatagtta
    50161 cctcgctaaa aatagtcatc gcccgattgc agagatagct atttcttatg ctggtgaagc
    50221 tagcctggca ttaaccttaa aagaaagaat cgcagcttat tacaaccact ctatttcggt
    50281 tttagaaaca ggctctatca tccaaacaca tacaggagaa ggagcttttg cggttatggt
    50341 tcgttatgaa taatcgtcat ttatttagtg ggatattttt ctttgttatt agtttatgtc
    50401 tggccttttt attgctaaat attattatcc ctaagtcaaa ttcacgtttg aaaaagagtg
    50461 attttctgac aaaagaacaa gtagctatcc aatatgttgc tataggagat tcattgacag
    50521 aaggagtagg tgatctaact catcaaggtg gttttgttcc tttgttaacg aatgatctca
    50581 gtgaatattt taaggctaat gttaatcatc aaaattacgg cgtatctggt gataccagtc
    50641 aacaaattct tgataggatg ataaaacaaa agcagataca gttatcttta aaaaaagcag
    50701 atataatgac gttaaccgtt ggtggtaatg atgttatggc agttattcgg aagaatttag
    50761 cggatttgca agtttctagt tttagaaagc cagctcgtca gtatcaaaaa cgattaagac
    50821 agattatcga gttagccaga aaagataata aagatcttcc tatttttatt ttaggcatct
    50881 ataatccgtt ttatttgaat tttccagaac taactgatat gcaaaaagtg attgatgact
    50941 ggaataccaa aactaaggag gttgttggag aatacgatcg tgtgtacttt gtgccaataa
    51001 atgacctctt gtataaaggg ataaatggac aagaaggaat tgttcattct tcaggagatc
    51061 aaactacaat tgtcaatgat gccttgttta ctggggacca ttttcaccca aataatactg
    51121 gctatcaaat catgtcaaat gcagtaatgg agaaaataaa aaagcatgaa aaaaaaatca
    51181 aaccttaatt ggtggaagtg gagcttctta tgtctgcttg cttttaatac cgcctttttg
    51241 atggttattg caagtcgtct cattcaagta agagaacctg agtcagaact gattgctaaa
    51301 aaaccagtta aaaatatcaa aattggtaca tttgtcacaa ccagagaaca gcttaacgaa
    51361 actgtagcaa gttatcttaa agattatcag actaaaaaaa tgtcttataa attttatgcg
    51421 acatcttctt ctattttgtt tgaaggaact tatcaattat tagggtatga agtcccttta
    51481 tatatctatt ttcaacctca tcgtctagaa aatggagctg tccaactaca ggtgatctct
    51541 ttttcagtgg gaactctgcc actcccagaa aaagatgttt tgcagtattt gaaatcaagc
    51601 tacaaattgc caagctttgt taaagtgatg ccaaatcaat cagctatcgt tgttaattta
    51661 caagatatcc aaaatgatgc taaggtttat ttaaaggcca agaaaattga tttatttaat
    51721 gatgaaatca gttttaacat ctataagaaa taagctcaaa taacgttaaa tacttgacct
    51781 aatcgctttt tttagatatg ataatatctg ttaaagcatt aagcttacta attatttgga
    51841 ggatttgtta aatggctaac aaacaagatt taatcgcaaa ggttgcagaa gcaactgaat
    51901 tgactaaaaa agattcagca gcagcagttg atgccgtgtt ttctacaatc gaagctttcc
    51961 ttgctgaagg tgaaaaagta caattgatcg gttttggtaa cttcgaagta cgcgaacgtg
    52021 cagctcgtaa aggtcgtaac ccacaaactg gtgcagaaat tgaaattgca gcttcaaaag
    52081 ttccagcctt caaagctggt aaagctctta aagacgctgt taaataattc gtctagaaaa
    52141 atcttgttgc tatcgatgtt tattgatagc gacaaggttc ttttttatat ttggggcata
    52201 tttggggcat aaagttagta gttttctctt cagttaagcc aagttctaat gcatgcactc
    52261 tataatggtc agtcatcctt ctattagtat atcatttccg caggtagggg gagttttttt
    52321 catatttgca aatagtcgaa gttaggattt ttgaaagcaa aaggtaagtt taaaaaagtt
    52381 tatttagaat gcttctaaat tacttgactt atttatttag aattattata attaatgtat
    52441 cttaaagatt gaataacttt taattgcgag ggaactaaaa atgacaatca gacaatggat
    52501 ggcagaccat cttcatttaa tggagacttt agcgtgtttg gtattaataa taattggcct
    52561 agccttttta cactcatttc cacaagtggc ttccgctatt ttcattacag ccttcttgat
    52621 tggaggatat gcgtctgcaa aaacgggtat attggatttg gtgaagaaca aacacttgtc
    52681 agtggatatt ttgatgattt tagcagctat cggtgctgga attatcggct attggctgga
    52741 gggtgctctg cttattttta tcttttcgtt gtccaatacg cttgaagaaa tggccatgga
    52801 aaaaagtaag gatgctattt cagccttgat gtccttgacg ccagatacag ctcgtcaata
    52861 ccaagaagat ggccatattt tagaagttga gaccagatcc ttgagtgttg gtgaccgttt
    52921 acaagttcgt aaaggcgaag ctgttccaat tgacgggcag ttgcttagtc cttttggtca
    52981 atttgatgaa tctatggtca ctggtgagcc tatcactgtt gataaggcag aaggccagga
    53041 tctgattggg ggaaccatta accaaggaca aaccatagat atgttggtta ctattgaaaa
    53101 tgacgatact ctctttgcca agattattaa tctggtggaa tctgcccaag aaaagaaaag
    53161 caaaactgcc acctttatcg aaagcttaga agatggttat gtcaaatttg tgctcgtcct
    53221 tattcctgcc tttatcctct ttagccactt tgtgctttct tggacttggt tggctgcttt
    53281 ttaccgaggg atgattctct taacagtagc ttcaccatgt gccctaattg ccagttccac
    53341 acctgctagc ttggctgcta tttctcgtgc agccagaaag ggattgatta tcaaaggagg
    53401 ggatattgtc gataacatgg gagatattaa ggctgttgtc atggataaaa cgggaacgct
    53461 cacccaagga aaaccttctg ttgtgaatgc tcattatttg gaagatgagt tgctcgtgaa
    53521 tagactggta aaaggagcag agactgctag tacccatcct atttctaaag cccttcttga
    53581 atacactgaa aaattggagc cactgacctt tgaccactta gaagaaattt ctgggaaagg
    53641 ttttcagggc ttctatcaag ggcaagaatg gcgaattggc aagaaaacct tcattttgga
    53701 aaaggttcaa gacctatcag cttttgaaga aactattcaa gtggaagaaa atcaagggaa
    53761 aaccctaatc tttgtttcac gtgaccatca attgatagct tactatgccc tcttggatga
    53821 tatcaaaata gaatcaaaac gtgctattaa gtctcttcat gccatgggaa tcaaaacagt
    53881 catgttaaca ggtgaccaag aacgaaccgc caattatgtg gcacaaaaac ttggtattga
    53941 tgaagtggta gccaactgta tgcctcaaga taaggtggct aagttagcag aattaaagac
    54001 caaatatggt tttgtggcca tggtaggaga tggtattaat gatgctcctg cccttgctca
    54061 agcagatgtt tcttatgcta ttggatcagg aacagatatt gcaatggaaa gtgcagacag
    54121 tgtgattatg gatgacttga ctcgtattcc attttcgatt caactttccc gcaaaatgaa
    54181 gaccattatc aaacaaaata ttgtttttgc cttatctgtg attaccttat tgattttagc
    54241 caatgttttt caggtagtta acttgccgct tggtgttgtt ggacacgaag gctcaacgat
    54301 tttagtgatt ttaaatggct tgcgtttact ttcttttaaa taatttagaa acttgcttga
    54361 aaacttgaaa gtgtttataa taatagtaag acttatgaaa gagaaaaccg ccgtatgttt
    54421 actattatga tcattggttt agctgtattt tcaataatta aaatcattct atttttctat
    54481 ttttatcagc aatttgagcg caagcaaaaa agaaaagttg aatcaaacaa ccagcaaaga
    54541 cagtcccaag aaagtgacgc tgtcccttca aaaaaattcc cattttaaaa agcttggaaa
    54601 gtgtacaaag tgcacatttc caagcttttt tgactattaa ggttaatctt tgtaacgtaa
    54661 gttcccacga aaatcgtcta agctttggta gcctttttct accataatcg tttttagttc
    54721 cttagtgacc cgttcaaaga tagctggccc ttcttgatga agggctgtcc caatttggac
    54781 catgctggcg ccacaaagaa tatgttcaaa ggcatcgcgt cctgttttaa ctccccctgt
    54841 accaataatg tggatagaag gttttaagcg tttgtaaaac gcatggacat tggctagagc
    54901 agtaggtttg atgtaatctc cacctatacc accaaagcca tttttaggct tgatgaggac
    54961 ttgttcatcc tcaatgacca gcccatttcc gatagaattg acacagttaa caaaggaaag
    55021 ggggtattta ttgaaaatcg cagccgcttg atcaaaatgc acaatgtcaa aataaggagg
    55081 taatttgata ccaagaggtt tagtgtaata ggtaaagatg ttctctagaa gttgatcagt
    55141 ggtttcaaaa tcataagcaa tctgtggttt tcctggaacg ttagggcaag aaaggtttag
    55201 ttccactaga ccctcataat ctgaagccat gatggctttt aaaatggttt cggtttcagt
    55261 aggagatagc ccgacaacgg agagaaagtg aggtttatgt tgcccggttt tggcaagatc
    55321 actgacaaag tctaagtagt agcgaaaacc attattaggg agtcccattg aattgataga
    55381 accaagacga gtatctgcgt agcgaggttc tggattacct ggacgaactt caagcgtccc
    55441 tgttttggtg acaaaggaag cggcttgaga cttttcaacc tccataagct cttcttttgt
    55501 catgcagtaa acaccagcag cattcatcaa acagttatca aaagagaaat gaccaatttg
    55561 cgtagcagta gaaaccatta tttcctccat attttagaca aattttttct attctaccac
    55621 taggcatgaa taatagcaag ctattttcac aaaaatgtaa atatattact gttattgacg
    55681 aacatttgaa attttcatga tagtcacatt atgattttca ataaagtcag aatagactag
    55741 cttttttgct atattttttg taaaatagga attgtaaaaa ggtagcaacc tttaaattaa
    55801 aaggagatat taactcatgg taaaattggt tttcgctcgc cacggtgagt cagaatggaa
    55861 caaagctaac ctcttcactg gttgggcaga tgttgatctt tcagaaaaag ggacacaaca
    55921 agcgattgat gcaggtaaat tgatcaaaga agcaggtatt gaatttgacc ttgctttcac
    55981 ttcagtattg acacgtgcta tcaaaacaac taaccttgcc cttgaaaatg caggtcaatt
    56041 gtgggttcca actgaaaaat catggcgctt gaacgagcgt cactatggtg ctttgactgg
    56101 caaaaacaaa gctgaagctg cagaacaatt tggtgatgaa caagttcata tctggcgtcg
    56161 ttcatacgac gtattgccgc cagctatggc taaagatgat gagtattcag cacacaaaga
    56221 ccgtcgttat gctgatcttg acccagctct tattccagat gctgaaaact taaaagtaac
    56281 tcttgaacgc gcaatgcctt actgggaaga aaaaattgct ccagctcttc ttgatggtaa
    56341 aaacgtcttt gttggcgcac atggtaactc aatccgcgct cttgtgaaac acattaaagg
    56401 tctttcagat gacgaaatca tggatgtgga aattccaaac ttcccaccac ttgtttttga
    56461 attagatgaa aaacttaaca ttgttaaaga atactacctt ggtggtgaat aacttaaaaa
    56521 ccagactttg gtctggtttt ttggttctat atcctaagaa gaaagaaaac cctgcttaaa
    56581 aatatgatat gatagaaata aaaaaggata gatagattat gaaagcagaa gatcgtcgtc
    56641 aaaaaattat tgagtgctta aatagtgaac aaaaagctgt atctgctact cgtttaggta
    56701 agttattagg agtgagtcgc caagtaatcg ttggagatat agctcttctt cgagctcagc
    56761 agattgatat tatttcgact ccaaaaggtt atattatgtc aacagcgctt tatagtcacc
    56821 aattttgtgc acgtattgtg tgccaacata atgtagaaga aactaaaaaa gaattagaaa
    56881 ttattttagc tcatcaaggg attattacga cggtagaggt agaacatcct atttacggta
    56941 tgataacagc ccctttaaat attaagacac actctgatgt aactaatttc atgtccaaac
    57001 tcagtcaatc taaagcagag ttattgtctt cgttgacaga aggactacat agtcacttaa
    57061 tttcgtgtcc tagtcaagaa gcctttttag ctatcaagca tgatttagaa ttagcaggta
    57121 tcttatacaa aggaatataa ctatagtata ttatgccatt gatggttgtt atgaatacca
    57181 tgctaaaata ttctattgat tatttatcag caacaaggta tcgtttaaaa ataccaaaag
    57241 atacaggtgt cttgatagtt attggttttt aaggtatact atttttgaaa aggagataaa
    57301 atgactaaaa aaccaacaca actaatagct tatacctcta ttttggtcgc atttgcgatt
    57361 ttgattccga taatcatgcc tcttaagctt attattggac cagcttcctt tactctggcg
    57421 agccatgttc ctttgttttt ggctattttt atgtcgattc cagtagcaat tttggtcgct
    57481 cttggtacca cattaggttt tttattagct ggacttcctt taattattgt tttaagagca
    57541 ctctctcatt tattgtttgc tattttggca gcgtggtggt taagtagaaa accacaactg
    57601 atgacatcgg cagtaaaatg ttttagtttt gcgtttttca ttaatgtcat tcatggcttg
    57661 gctgaatttt tagttgtcta tattttaaca gcaaccacag caacttctat gtcttatttt
    57721 tggtctatgc taggcttgat tggcttaggt tcgcttattc atggcatatt ggatttctat
    57781 cttgctttag ttctatggcg ttttttagca aaaaacttaa aacttcccac cataaatgcc
    57841 taagactaaa atagagatag ttatatgata atgacgagcc ctttcttgtt gaaagggctt
    57901 gcatttttta ggaaaattga tatactaaag tgtgtgtttg tgaatacagt aacaaaagga
    57961 gatatcatga aaacaccaga acagatttta gaagcaacta ttcatattgg ggaacataag
    58021 gttaccaaaa cttttttggc taaatctatc ttaggcttta ttggtggagc gatgattagc
    58081 cttggttatt tactctacgt gagaattgcc gccagtggtt tagaaacttt tggtgctttt
    58141 tccagtatcg taggagcttg tgcttttccg attggtctaa ttattatttt aatggcgggt
    58201 ggagaattaa ttacagggaa catgatggct gtttctgcag ctttgttggc caaaaaaatt
    58261 aagtttagcg agcttgccaa gaattggctt atcattacct tgtttaatgt gattggagct
    58321 gtttttgtag cttttgtgtt tggtcatttt ctaggcttaa catcagctgg tatttttaaa
    58381 gaagaagtga ttgaggtggc ccatgctaaa atagcagcga gccctttgca ggcactagta
    58441 tcaggaattg gttgtaactg gtttgttggt ttggccttgt ggctatgcta tggggcaaat
    58501 gatgctgctg gtaaattcct tggtacttgg tttcctgtca tgacctttgt agcccttggt
    58561 tttcagcata gtgtagcaaa tgcttttgtc attcctgctg ctatttttga aggaggagca
    58621 acatggttgg attttgccac taattttatt tttgtctata gtggtaatat tatcggtgga
    58681 gccatttttg ttagtttttt atattttaaa gtttactatc atccgcaaaa gagtaaaact
    58741 caatgagaaa atattttttt agactgaggg cgtcctattc tcagtcttct ttttataatt
    58801 tatggtaaaa taagaagcga agtttaaaaa atttagctaa ataatggtta gtttattccc
    58861 taaaaaagga gtattcccaa aaaatccgta aaaagaattt gctatgggag tagttcccaa
    58921 aataatgcag atcattagtt gtctttcaaa aatagccttg atagggtaaa aagtggacag
    58981 tgatgcagca acagattcat caggcgtaca aactgtctta tggtttgtgc ttagagattt
    59041 cttaataatg cttttggtaa tacactttta gtgaagaaag tgtagcatga aagcttaaag
    59101 ataaccatga gttcgcttta tgcactcttg ttgagaaaaa tagcatagtc aattgagtaa
    59161 acatcatttc tgcatggaat gaaacaattc ctataaactt atatcataag gatggtttgc
    59221 ggtttctaaa aaagtaaaat gaatcaaaaa acaaaagcca aatatctcaa ggccaaggta
    59281 acaagtcgag taaaaaagtt tttacttggc taatccaaac ggttctgtca cgattcacgc
    59341 taaaattgga actgctgaga cttgtatcac agacaattca gatcagacct tagtaactta
    59401 caacttaaat gtagtagctt ataatacaaa taacgaagat aatattgcgg ttgctgttat
    59461 gtatccacat attacgaata tatcggcaaa gatgtgaggg cgctttatgt ggcgatatat
    59521 ggaaaacaat aaaggagaac ttagtgcttt atccaacacc cattgcaaag ttaattgaca
    59581 gttactctaa acttccagga attggtatca agacggcgac gagattagcc ttttatacta
    59641 ttggaatgtc aaatgaagat gtcaatgatt ttgctaaaaa cttattagca gctaaaagag
    59701 aactgaccta ttgttcgatt tgtggaaacc ttaccgatga cgatccttgt cacatttgca
    59761 cagacacgag ccgtgatcag acgaccattc tggtagtaga agatgctaaa gatgtttctg
    59821 ccatggaaaa aatccaagag tatcatggct attatcatgt gcttcacggc ttgatttcgc
    59881 ctatgaatgg tgtggggcca gatgacatca accttaaaag tttaattacc cgtctaatgg
    59941 atggtaaggt gagcgaagtt atcgtagcta ccaatgccac agcagatggg gaagcaacgt
    60001 ccatgtatat ttcacgtgtc ttgaaaccag ccgggattaa ggtaactcgt ttggcaagag
    60061 gtctcgcagt aggttcagat attgagtatg ctgatgaagt aacattattg agagctattg
    60121 agaatcgtac tgaactttaa tgatcatgtt ggtgccttta ctcgcaaaga gaggttttga
    60181 aaaggctaca tctttttgtt ataataaaaa aacattcaat tcagataaga aaggttagct
    60241 atgtccaaac aaacgttagt tctattatac ggaggccgct cagcagaacg tgaagtctca
    60301 gtgctttcag cagagagtgt gatgcgagca gtcaactatg ataagttctt agtaaaaact
    60361 tattttatta ctcagatggg ccaatttatc aaaactcagc aattttcaga aaagccatcg
    60421 gaatcagaac gcttgatgac aaatgagacg atagagctaa ctcaaaaaat aaaaccaagt
    60481 gatatctatg aagaaggtgc agttgtattt cctgtattac atggacctat gggagaagat
    60541 ggctctatcc aaggtttctt agaagtgctt agaatgccat atatagggac taatgtcatg
    60601 tcttctagca tagctatgga taaaattact actaaacgtg tcttagaatc aattggaatt
    60661 ccacaagttg cctatactgt ttatattgac ggacaagatt tggaggcttg tttagttgaa
    60721 actttagcaa gacttacttt tcctatcttc gtaaaaccag ctaatatggg ttcttctgtg
    60781 gggatttcca aagcccaaac aaaagtagaa ttaagaaaag cgattcagtt agccctgacc
    60841 tatgacagtc gtgtcttgat tgaacaaggc gtggttgcca gagaaattga agttggtctc
    60901 cttggaaatg ataaggttaa atcaactcta ccaggagaag taatcaagga cgttgatttt
    60961 tacgactacc aagcaaaata tgttgacaat aagattacga tggccattcc agcagatgta
    61021 gaccagagta ttgtgacaga aatgcgttct tatgctgaag tagcctttaa agccttaggt
    61081 ggttgtgggt tgtcccgttg tgactttttc ttgacccaag acggacaggt ttaccttaac
    61141 gaattaaaca ccatgccagg ctttacccaa tggtctatgt atccactctt atgggaaaat
    61201 atgggattgg cttatccaga tttgattgaa gagctggtga cactggcaca agaaatgttt
    61261 gaccagcgtg agagccacct gatttaaacc tatgagatga ataaacattg acttggatgg
    61321 aacggcaaac atcgtcaaga tgtgacgttc gtcctttttt tgttgctctt ttaggaagaa
    61381 tagtagagcc attaagggag tttgacattt tagaaatttt tctaatgttt tgtgctataa
    61441 tagataggac atcgtaaata ctagtgttct tagaaagaaa acaaaatgaa attaacctta
    61501 cacgaagtgg ctaaaatagt tgacgcccaa aataatgtgt ctgacttaga cgacgttcct
    61561 ctgcatcaca ttgaatttga tagccgaaag attacaaaag gagacctctt tttaccctta
    61621 aaaggtcaaa gggatggtca tgagtttatt gatttagcct ttcaaaatgg agctgtcgct
    61681 actttttcag aaaaagaatt gccggggaaa cctcaccttc ttgttgaaga ctgcctaaaa
    61741 gcttttcaaa agctagccca ttattatatt gataagatgc gcgtggatgt tattgctgtg
    61801 acaggctcaa atggtaaaac ttccaccaaa gatatgatag gagctgtcct atcaaccact
    61861 tacaaaactt acaaaacgca aggaaattac aataatgaga ttggtttgcc ttacaccgtt
    61921 ctccacatgc ctgacgatac ggaaaaaatt gttcttgaaa tgggacaaga tcacatggga
    61981 gatattcgtc ttctgtctga aattgcaagg cctcgtattg cagttttaac cttagtcggc
    62041 gaagctcatt tagaatattt tggaagccga gacaaaatag cccaaggcaa aatgcagatt
    62101 gttgacggca tgaattcaga tgggatttta attgctccgg gagatccgat tattgaccca
    62161 tatcttccag aaaatcagat ggttatccgt tttggaaatc agcaggaaat tgacgttact
    62221 ggtattcaag aagacaaaga tagcttaacg tttacaacaa atgtgttagc aacacctgtg
    62281 tccctacctc taccaggaaa atacaacgcg accaatgcta tggtagcagc ctatgtagga
    62341 aaactattgg cagtaacaga cgaggatatt atagctgctt tacagactgt gacgttgaca
    62401 ggtaatcgta cggagtggaa aaaagcagcc aatggtgctg atattttatc agatgtctac
    62461 aatgccaacc caacagccat gcgtctgatt ttagaaacat ttgctaacat agcaaagaac
    62521 cccggaggaa aaaagattgc agtgctagca gatatgaaag aacttgggaa ggattcagtg
    62581 atacttcatt ctcagttaat tgacagctta acatcaggta atattgatca gcttgttttt
    62641 tatggggatc atattaaaga attagcacgg ttggcaagtc aggtttatcc tgctgagcaa
    62701 gtacattatt ttttaaaaac tgaacaagaa gaccagtttg aagccatggc acaatatgtt
    62761 caaaacattc ttaatccctt tgatcaaatt cttttaaaag gcagccactc gatgtcgcta
    62821 gaaaagttag tggatcgatt agtgactgac aagaattgtg atagctatca gccttgattt
    62881 ttataaaact ttcagataaa gtcttgttct ctcatgaaga ttaaggtata atgaaaaaat
    62941 atagaaaggg acgattatgg atttttttgc aattgacccc atcggactgc ctcatacctc
    63001 acttatcttt tacttgtcgt cactcttgat agcgcttttg cttgtttttt tgacttttca
    63061 agcatatagg ttaaaatctt atcgatattt tttcttgttt ttacagttat ctcaggtgat
    63121 tggcttgtac acatggtacg tgttaagggg gtttccttta gatgaagctt tgccgttgta
    63181 tcattgtcgc atcgctatgt tagctatctt ttttctacct gatcgtaaca agtttaagca
    63241 attatttatg gttttgggga taggtggaac attccttgca cttttatcgc cagatcttta
    63301 tccgtttaga ttatggcatg tagcaaatgt ctcgttttat cttggtcatt atgctttgtt
    63361 agtgaatggt ttgatttacc tcttgcgttt ttacgatgcc agtcagttaa gactgctatc
    63421 agtagtacgc tatttagcaa ctgttaactt tcttcttctg ttggtcagtt tagccacgaa
    63481 aggaaattat ggttttgtga tggatattcc agtgattcat acgcgtcatt tgctacttaa
    63541 ttttgtgatc gttacaagtg gcttgacttt tatggttaaa ataaccgaat atttttacct
    63601 taaatttggt gaagctcaac agctggcatt tgctttctct aaagaaaagt aggtcgttga
    63661 aaaagcactt aaaatcagct ataataagaa gagtctggga tgatttccag gctcgatttt
    63721 tttaaaaaag atactcattg atagcccaag ataagttata ataccagttt tgaagaactt
    63781 tagaggctaa tcgtatatgg agaaacccaa tgtagcccaa ctcttttgat aaacaagtaa
    63841 tacctaacga aaataactca gagaaaagct ctgccatttt actatacaag gaaaaaagaa
    63901 tgtcacttac agaagaaatt aaaaaacgcc gtacttttgc catcatctct cacccggatg
    63961 ctggtaagac gactattact gagcaactat tatattttgg tggtgaaatt agagaagcag
    64021 ggacagtaaa agggaaaaaa tcaggtacgt ttgcaaagtc cgactggatg gatattgaaa
    64081 agcaacgtgg tatctctgtt acttcatctg ttatgcaatt tgattacgcg ggtaaacgtg
    64141 ttaatatttt ggatacacct ggacatgagg atttctcgga agatacatac cgtaccttaa
    64201 tggctgtgga tgcggctgtc atggttgtag attcggctaa aggtattgag gcgcaaacga
    64261 aaaaactttt tgaagttgtc aaacatcgta atattcctgt cttcaccttt attaacaagt
    64321 tagaccgtga tgggcgtgag cctttagaac tcttggaaga attagaagaa gttttaggga
    64381 ttgcttctta tccgatgaac tggccgattg gtatgggacg cgcctttgag ggcttatatg
    64441 atttacataa taaacgttta gaactctata agggagacga gcgttttgca agtattgaag
    64501 acggtgatca gctgtttgcc aataatccct tttatgaaca agtcaaagaa gatattgaac
    64561 ttcttcaaga agcaggtaat gtcttttcag aacaagctat tcttgatggt gacctaactc
    64621 cagtcttttt tggctctgcc cttacgaact ttggagttca gacttttctt gatactttct
    64681 tggagtttgc cccagaacct catggtcaca agactacaga aggtaatgtt gttgacccct
    64741 tagctaaaga tttttcaggt tttgtcttta aaattcaagc taacatggac cctaaacacc
    64801 gtgaccgtat tgcttttgtg cgtattgttt ctggtgaatt tgagcgcggt atgggagtta
    64861 atttgacacg cactggcaaa ggcgctaagc tctccaatgt tactcaattt atggcagaat
    64921 cacgggaaaa tgtgacgaat gctgttgctg gggatattat cggggtttat gatacaggaa
    64981 cttatcaagt tggggatacc ttaacagttg ggaaaaataa atttgaattt gaacccttac
    65041 caacttttac cccagaaatc ttcatgaagg tttctccgaa aaatgttatg aagcagaaat
    65101 ccttccacaa aggtattgaa caattagtac aagaaggagc aattcagctt tataagaatt
    65161 atcagacagg cgaatacatg ctgggtgctg tgggtcaact gcagtttgaa gtctttaaac
    65221 atcgtatgga aggtgaatac aacgctgaag ttgtgatgac accaatgggt aaaaagactg
    65281 ttcgctggat ttcagaagat gatttggatc aacgcatgtc ctcaagccga aacattttag
    65341 ctaaggatcg ttttgaccaa ccagttttcc tatttgaaaa tgattttgcc cttcgctggt
    65401 ttgcagacaa atacccagat gtcactttag aagagaaaat gtaatcgaaa catgattttc
    65461 aacagtctaa cgttttggag atcaatttac tgagcaactt tttaaaagaa atgagtggct
    65521 agttatctct tttgcagatt taagattcta tcaaaaaacg atatcttcac aactgtaagc
    65581 atatttatga tttagcggat aatcgtgaaa gcgtgttatt gcttatatta gccttatttc
    65641 ctatcttttt gattctaatt gtgttacact agttaggttg ttaatcaaac gacgaaaatt
    65701 aaaaggttta taaggcagct tcgcactgcc tttttagaaa agagaaacaa ttgaaattta
    65761 cagaatttaa cttatcacaa gacatccaat cagctgttgt taccgctggt tttgagaaag
    65821 catctcctat ccaggaaatg acgattcctc tcgcactaga agggaaggat gttattggtc
    65881 aagcacaaac aggaactggt aaaacagcag cgtttggtct accaaccttg aataagattc
    65941 gtactaacga aaatatcatc caagcattgg tcattgcacc aacgcgtgaa ttggctgtac
    66001 aaagtcagga agaattgttc cgttttggac gtgaaaaagg ggttaaggtt cgctctgttt
    66061 acggtggatc aagtattgaa aaacaaatca aagcccttaa atcaggtgcc cacattgtcg
    66121 tgggaacacc gggtcgcttg ttagatttga ttaagcgcaa ggctcttatt ttagatcatg
    66181 tggaaacctt aatccttgat gaagcagatg aaatgcttaa catgggattc ttggaagaca
    66241 ttgaagctat tattagtcgt gtcccagcag accgtcaaac cttgctcttc tccgcaacga
    66301 tgccggcacc tattaaacaa atcggggtta aattcatgaa agaccctgaa catgttcaaa
    66361 ttaagaacaa agaattaaca aacgtcaatg ttgatcaata ctatgttcgt gtgaaagaac
    66421 aagaaaaatt tgatactatg acccgtctga tggatgttaa ccagccagaa ttatccatcg
    66481 tttttgggcg gactaagcgc cgagttgatg aaattacacg tggcttgaaa cttcgtggtt
    66541 tccgtgccga aggaatccat ggtgatcttg accaaaataa acgcttacgt gttatccgtg
    66601 atttcaaaaa cgaccaaatt gatattcttg ttgccactga tgtagcagcg cgtggccttg
    66661 atatttcagg agttacccac gtttataact acgatattac ccaagatcca gaaagttatg
    66721 ttcaccgtat tggtcgtaca ggtcgtgccg gtaaatctgg tgagtctatc acttttgtct
    66781 caccaaatga gatgggctac ctctcaatga ttgagaactt aacgaaaaaa cagatgaaac
    66841 ctcttcgtcc agcaactgct gaagaggcct ttcaagccaa gaaaaaagta gccctcaaga
    66901 aaattgaacg cgactttgcg gatgagacta ttcgttcaaa ctttgataaa ttcaaaggcg
    66961 atgctgtcca attggctgcc gaattcactc ctgaagaatt agctttatat attttgagct
    67021 taacggttca agatccagat agcttaccgg aagttgaaat tgcacgtgaa aaaccattac
    67081 cattcaaata tgtgggtggt ggtcacggca ataaaaatgg caaaggtggt cgtggacgtg
    67141 acaaccgtaa ccgtggtgat cgccgtggtg gctatcgtgg tgaccgtaac agagatgagc
    67201 gtgatggtga ccgtcgtcgt caaaaacgtg ataagcgtga tggtcacgat ggcagtggca
    67261 accgcgattt caaacgtaaa tcaaaacgta atagtaaaga ctttttcaat aaagagaaaa
    67321 aatcaagtgc taaaaatact ggttttgtga ttcgtcacaa aggtgaataa gcttaaagag
    67381 agttgatgag agtcagctct ttttaatttt ctgaaaaagt tgcttttata atgggatctg
    67441 ttataatggt ttcagttatt tcattataat ttttaaaaaa ttaggaggag tataagatgt
    67501 ctgatagcca tcttactgcc tttgacaaag cttcaaaagc aggttttatt attgctttag
    67561 gtattgttta tggagatatt ggaacaagcc ccctttatac gatgcagtct ctagttgaaa
    67621 atcaaggagg ggttaatcag gtttctgaat cctttatttt aggatcaatc tctttaatta
    67681 tttggacact gaccttgatc acaacaatca agtacgtttt gattgctcta aaagctgata
    67741 accaccatga aggtgggatt ttttctttat tcaccttggt acgtaaaata tcaccgtggc
    67801 tcattattcc ggcgatgatt ggaggtgcaa cacttttgtc tgatggggct cttacacctg
    67861 cggtaacagt tacttcagct attgagggct tgaaagccgt tcctggtctg agtcacatct
    67921 accaaaatca aaccaatgtc attatcacaa ctctagtgat tttaatagtc ttgtttggta
    67981 ttcagcggtt tggaacaggt tttattggta aaatttttgg accagttatg tttatctggt
    68041 ttagttttct aggtgttagt ggttttttta atacgttggg gcatctggaa attttcaagg
    68101 ctatcaatcc ttactatgct ctgcatttgc tgtttagtcc tgaaaaccat cgtgggattt
    68161 ttatcttggg gtccattttt cttgcgacaa caggagctga agccctttat tcggatttag
    68221 gacatgttgg tcgaggaaat atttatgtga gctggccctt tgttaagatg tgtattgtgt
    68281 tgtcttactg tggccaggct gcgtggattt tagcgaataa acactcaggt attgaactaa
    68341 accctttctt tgctagtgtg ccatcacaat taagagttta ccttgttagt ttggcaacct
    68401 tggcagctat tattgcctca caggctctta tttcaggctc ctttaccttg atttcagagg
    68461 ccatgcgttt gaaaattttc cctttgtttc gtgtgactta cccaggggca aatttggggc
    68521 aattgtatat tcctgtcatt aactggattt tatttgcagt gacctcttgt actgttttgg
    68581 cttttagaac atcagcccac atggaggcag cttatggtct tgctattacc atcaccatgt
    68641 tgatgacaac aatcctctta aagtattact taatcaagaa aggaacgaga cccatcttgg
    68701 ctcatttagc gatggctttc tttgcccttg tagaattcat tttcttcttg gcttcagcta
    68761 tcaaatttat gcacggtggc tatgcggttg ttatcttggc acttgcaatt gtctttgtca
    68821 tgtttatctg gcatgcgggc acacggattg ttttcaagta tgtgaaatct cttaatttga
    68881 atgattacaa ggagcagatt aaacaacttc gtgacgacgt ttgttttgac ctctaccaaa
    68941 caaatgttgt ctacttatcc aatcgtatgc aggatcatat gattgaccgg tctattttgt
    69001 actccatttt agacaagcgg ccaaaacgcg ctcaagttta ttggtttgta aatgtccagg
    69061 taactgatga accttataca gctaagtaca aggtagatat gatgggaacg gattatatgg
    69121 ttcgagtcaa cctttatctt ggttttagaa tgccacagac tgtgccacgc tatttgcgca
    69181 cgattgttca ggatttgatg gaaagtggcc gtttacccaa acaagaacag gaatatacca
    69241 tcacacctgg tcgtgatgtt ggtgattttc gctttgtttt aatagaagaa cgggtcacca
    69301 atgcacgtca attgagtaac tttgaacgct ttattatgca gactaaggca agcattaaac
    69361 atgttaccgc tagtccaatg cgttggtttg ggcttcaata ttccgaagta acccttgaag
    69421 tggttccctt gattctatca gatgtcttga agttaccaat caaagaattg gtgcctgtgg
    69481 aagacagtga agcataaaaa aatcattgag atgataagtc tcaatgattt ttcttttctt
    69541 tttgatgagt agcaatatag gccaatttct ggcttcttgt ttttcgtttt ttaaagagtg
    69601 cttcagcgct catcgcagcc tctttgctat caaacacttc gtaataaagt aaagaaacag
    69661 gtaaccggta gcgagtatat ttagccccct ttcctgcgtt atgtgtagct aaacgctttt
    69721 tcaaatcagt tgtataacca gtgtagaggg ttttatctgc acattctaac acatacatat
    69781 aagctttttt agtggtcatg attaggtttt cctttggaag cagcaccaaa ataaatctca
    69841 aaaatatgat cagtgtattc tccgttttcc ttgtggacaa ctaaaggagg taaaatagtc
    69901 atcccttcaa tagaaccgtc tttgattgct tcaataagta acatattagc tgatttacct
    69961 aatttaggat agacaaattg taccctttta ggggcaagac cattagctct aaggctatct
    70021 ataatttcca agaatcgatc tggtcgatga accattgcca gacgaccatt tgatttaagg
    70081 gcatgacggg ctacctgaca aatctcttct aaattagtgg tcacttcatg acgagccagt
    70141 aaataatgtt cagagacgtt cttcttagaa ctttcgtgac ttttaaagta agggggattg
    70201 cagagcatca aatcaactcc tgaacgtggc acatggttta ggaggttttt taaatcatca
    70261 caaatcatgg ttacttggtc ttccagttga ttgagctgga tagagcgttg tcccatatca
    70321 gcaagccgtt cttgtaattc tacttcaacg atggctgcct tggttctagt gctagcaaat
    70381 aagccaaccg ccccatttcc tgagcacaaa tccacaatta accctttgga aggcatcttg
    70441 gggaagcggg ataagaggac gctatcaata gagtaactaa agacatcctt gttttgaata
    70501 atgccaacat cacttgaaaa gagttgatca atacgttcgc cttcttttaa gattgctttt
    70561 atcatacctg ttattttaac ataaaatagg cttgaggtga atgtttgaag agtgattttg
    70621 actttcgaaa agtcagcttt catgatacaa taagtaagat tattctatta aaggagaagc
    70681 ctgtgtttta cgcttactta cgcggtttag tagtcttttt attatgggtt gtcaatggca
    70741 atgcccacta ccatcatgaa gaaaagatgt tagatgcttc tgagaattat attctggtag
    70801 caccccatcg aaccttttgg gatccagttt acatggcatt tgcagcacgt cctaagcagt
    70861 ttatttttat ggctaaaaaa gagttgtttg caaatcgtct ctttgcttgg tggattaaaa
    70921 tgtgtggtgc ttttcctatt gatcgtgaca aaccgagtcc agatgctatt cgttaccctg
    70981 ttaatatgct caaaaagagc aatcgttctc ttcttatgtt tccaagtgga agtaggcatt
    71041 cgcaagaggt caaaggaggg gtcgctgtga ttgctaaatt ggctaaggtc aagattatgc
    71101 cagcagccta tcaggggcct atgtcggtca agggattact agcgggagaa cgggttgaca
    71161 tgacttttgg gaatcccatt gacgtctcag atattaaacg catgaatgat gaagggattg
    71221 ctgaggtggc aaaccgtatt caggcagagt ttgatcggat ggatgacgag ttggcacctt
    71281 tccaaccagg aaaagcaagg aaccctttaa cttatctcta ccgtttacca ttaggattgg
    71341 ttttggtggt ggtattatta ttaaccatat tattttccta tattgctagt tttgtttgga
    71401 atccagataa acatcgccat taagaacatg agggctaaca tgtgcctgaa ataagaagtg
    71461 attgagatta gtcttctatt gaaagaagcc gctaatgctt aatcactttt ttcatttcta
    71521 aaaaagatat tcgatgatac ccttaactct tttaagcaca aaaaatgaca atactactat
    71581 acttttggat atcatttacg aataaaaaga tgaggtaaaa aaatgttaga cgaattatta
    71641 attaaaggaa aatcgttttt gagagagcgg tattttctgc catacctaat tagtctttta
    71701 ttaggacttt ttctaatact aagcttcagt tttttgttct ggggaaatag gcagagcaag
    71761 gcagccgttc ctgctttgag agaaatatcg cctgtgaaac agcaggttag tgaagaaaaa
    71821 aaggaaattc aagaagatag cagtatttta gtggatttaa aaggcgccgt acaaaaagag
    71881 ggagtttata agctaactgc tagcagtcgt gtgcgagatg tcattgaact agctggaggc
    71941 ctaacttcag aagctgataa acatgctatt aattttgcag aaaaactaac tgatgagcaa
    72001 gttgtttatg tacctaaaca aggagaagag atttctgtgc taccaagatc attagtttct
    72061 ggtaaaaaag aaactgccag caaggatcag tcaaaggttc atattaataa ggccagctta
    72121 gaagaactac aacatatccc aggtattggt gctaaaagag ctcaggatat tattgatatg
    72181 agagataagt taggtggttt taaagcgtta gaagatctcc gtcaggtttc ggggattggc
    72241 gaaaaaacgc tcgagaaatt aaaagatgac attttcttgg actaagctag tgcccctgtc
    72301 aaagattcaa tttgcttttt taatcttggt tctcttttat caaatccata gccctagctg
    72361 gttaacgttt ctccttagcc ttagtttgat ttgcttactt gtcaagcgtt tgtctaaaaa
    72421 agaatttctc ggtgtctttg ccatccttag tttctgtgct ttgtttttgc tgtatcagaa
    72481 acagcagttg attcaaaaac tggaaattca gccagtacaa ataacctctg tagcattagt
    72541 tcctgatagt attcggatta atggtgatca attactgttc ttggacgtca cgggaaacat
    72601 tcttatcagt tattttaccg tttgaaaagc caagcagaag cccaattgtt caagaaagag
    72661 caccgttggt tagtgatgca cgcaaaagtg acattggaaa aagctgagga agttcgaaat
    72721 tttaaaggct ttaattatca gacttttttg gcttatcaag gaatttacag gatagggaag
    72781 gtagagcaaa tagaacagct tgaagtgatt tcacccgagt caatatgtga ctatttgtcc
    72841 tctttaagac gacgagccat tgttcattgc cagcagcatt ttccaagacc tatgtctcac
    72901 tacctgacgg gcctcctttt tggttattta gataagtcgt ttggtgagat gacagattat
    72961 tatagtcagt tgggtatcat tcatctcttt gctttatcag ggatgcaggt tggcttcttt
    73021 cttacttgtt ttagaagggt gttgctatta ctcgcagttc ctttggaatg gataaaatgg
    73081 atagagcttc cttttgcttg cttttatgcc gcgttgacag gttatagtat ttctgttatt
    73141 cgaagcctcg tgcagtcgca gttgcgtcat ttaggaataa aaggattaga caatctggct
    73201 tgtacttttt tacttgtctt tttatgggat gctcatttct taatgactgt tggtggcgta
    73261 ttaacgttta gctatgcttt tttgttaaca gtggttactg ttgaagaatt atcaggagct
    73321 aaaagacagt tggtacaagt cttgaccatt tccctaggaa tattaccatt tttgctcttt
    73381 tatttttcta gttttaaccc catgtcaatg gtcttaacag ggctcttgtc ttatctcttt
    73441 gaccttttta ttttgcccct tctttgtctg gttttttgtc tatccccttt ggtgactgtc
    73501 tcaatatgta accatctttt tattttatta gaaaaagtca ttcaatttct cggaaatact
    73561 ttcaatagtt cccttgtttt tggaagcccg accagttggc acttgcttat cttggtgatt
    73621 agcttcgcta ttttttatga ttatcggcag gtgcgacaac gagttatcac ttgcggtttg
    73681 gttatagcgt tgacgctttt gtctgtcaaa tatcctttga ccaatgaagt gacctttatc
    73741 gacattggcc agggagatag tattttggtg agggagtgga cagggaaaaa tctcttaata
    73801 gatgtaggtg ggcgcccttt cttttcttca aaagagcact ggcgacgagg acatcacgta
    73861 gctaatgctc agaaaacctt aattccttac ttaaaaagta gaggtattca cacaattgac
    73921 caactattag taactcacgc agatactgat catatggggg atatcgaagt ggttgccaaa
    73981 gctattcgaa taaaggagat tttgactagt caaggcagtt taagccatcc aagctttgtt
    74041 aggcggctaa ggcgtttaaa atgtcacgtt agggttttag cagctggaga ccagttgcct
    74101 attatgggaa gtgtcttaca ggtactctac ccttggcagt taggggacgg gaaaaataac
    74161 gattctttgg tactttatgg caggctctta aatcgaactt ttcttttcac aggtgacttg
    74221 gaaaaagagg gggaaaacga gatcataaaa cgttatcctc aactaagagt agattattta
    74281 aaagcaggtc accatggatc aaatacctct tctagtgcag cttttttaga ccatattcag
    74341 cctaaagtgg cctttatttc tgctggaaaa aataaccgtt atcagcatcc tcacagagaa
    74401 accttagccc gtttggaaga cagacaaatt acttattacc gaacggatac gcaaggagct
    74461 attcgtttga ctggttggac aagctggcat cttgaaacgg tccgttagtt aaaattccag
    74521 cctgacgaag aaacaagcag tcgctttcct tttaggagaa agatgatata ataaaagcat
    74581 gattgcgata gaaaagattg aaaaactgag taaagaaaat ttgggtctta taacccttgt
    74641 cacaggagat gacattggtc agtatagcca gttgaaatcc cgcttaatgg agcagattgc
    74701 ttttgataag gatgatttgg cctattctta ctttgatatg tctgaggccg cttatcagga
    74761 tgcagaaatg gatctagtga gcctaccctt ctttgctgag cagaaggtgg tcatttttga
    74821 ccatttgtta gatatcacga ccaataaaaa aagtttctta aaagaaaaag acctaaaggc
    74881 ctttgaagcc tatttagaaa atcccttaga gactactcga ctaattatct ttgctccagg
    74941 taaattggat agtaagagac ggcttgttaa gcttttgaaa cgtgatgccc ttgttttaga
    75001 agccaaccct ctgaaagaag cagagctaag aacttatttt caaaaataca gtcatcaact
    75061 gggtttggga tttgagagtg gcgcttttga acaactgctt ttaaaatcaa acgatgattt
    75121 tagtcaaatc atgaaaaaca tggctttttt aaaagcctat aaaaaaacgg gaaatattag
    75181 cctaactgat attgagcaag ccattcctaa aagtttacaa gacaatattt ttgacttaac
    75241 cagacttgtc ctaggaggta aagttgatgt ggctagagat ttgattcatg atttacgctt
    75301 atcaggggaa gatgatatta aattaattgc tattatgttg gggcaatttc gcttatattt
    75361 acagcttgcc attcttgcta aagaaggaaa atcagaacag cagcttgtaa ccagtttgtc
    75421 agagatactt gatcggcggg ttaatcctta ccaggtcaag tatgcgttaa aggattctag
    75481 gaccttatct cttgcctttc taacaggagc ggtgaaaacc ttgattgaga cagattacca
    75541 gataaaaaca ggactttatg agaagagtta tctagttgat attgctctct taaaaatcat
    75601 gactcactct caaaaatagg cgttggaccg ctttccaaga gataatcaaa ttagttgaaa
    75661 gctcttattt tttgcgataa gatagacgta tcataaagga aaagaggaca ggaaaatggc
    75721 tattatttta ccagaacttc catacgcgta tgatgctctt gaaccacagt ttgatgcgga
    75781 gacaatgact cttcatcatg ataaacacca tgccacttat gtcgctaata ccaatgcggc
    75841 tttagaaaaa cacccagaga tcggagaaaa tctggaggaa ctattggcag atgtcactaa
    75901 gattccagaa gatattcgtc aagccttaat taataatggt ggcggacacc taaaccatgc
    75961 gcttttctgg gaactattat cacctgaaaa acaagacgtc actcctgatg ttgcacaagc
    76021 cattgatgat gcttttgggt catttgacgc ctttaaagaa caatttacag cagctgctac
    76081 tggacgtttt ggttcaggtt gggcatggtt agttgttaat aaagaaggac aactcgaaat
    76141 cacatcaacc gctaaccaag atactccaat ttcagaaggc aaaaaaccaa ttctagcgct
    76201 tgatgtgtgg gagcatgctt actacttgaa ttatcgtaat gtacgtccaa attatatcaa
    76261 agctttcttt gaaatcatta attggaaaaa agtatcagaa ctttaccaag ccgctaaata
    76321 agaaaagggt ttccaatctc aaaaagagat tggtttttta agtggttttg tgaataacag
    76381 tgtggggaca tcatttttta gaaaagataa aaatagtttg tctttttaat gtaattcctt
    76441 gatttttagc taaatttagc tagaatagaa tggataggag attttaggtg ttaagaaaga
    76501 agaaaactac cattgtaggg attattttag gaatgatgat agtgacctta cttgtcggct
    76561 gtttgactgg taaaaagaaa ggctttcctc ctaaagcagg tgagcggcag caaacggctg
    76621 acttaaaaat gaaaaaagat tagaaaaact gttcaaaaac cgttacctga aaaatctaaa
    76681 gaggctaagc aagctgttat ggatgcagat ttagcgcaaa tggatgcctt agggctctat
    76741 tacgatgaca accatttgag tttggtcaat acggtcaagg tgtatttaaa ggaatttggc
    76801 attggtgaat ctcaaattgc cttttcctac aaagacctca attcaggcag gactgctgcc
    76861 atgaatgacc atcagccaat gattgcagga agcacctata agctgccatt aaacatgctg
    76921 gtggtagata aggcaaatta tccatgacag agcgttttga cattacagaa actgattatg
    76981 aatatgatca ggaacatcat gcctatgttg ctcaattcaa tggtgccatg tctattccgg
    77041 atatgcaaga atattccttg gtgtactcag aaaacacgcc agcttatgct ctagcagaac
    77101 gattgggtgg catgaataag gcttaccaat tatttgaccg ctacgggaag gtatccggag
    77161 ctattacgac cattgatcgt aatggcaata aaatcaccac cgcttactat ttgcaaggtt
    77221 tggattactt gtggcagcat caggataaat ataaggatat cttgtactac attggtgaat
    77281 ctttccctga tttgtattac aagacttatt tgcctcatgt aaaggtttat caaaaaccgg
    77341 gttatgtcag agaagcctta aatgtaggtg ccattgtttg cgaagagtct ccttatttga
    77401 ttactcttta ttcatctggt ttaggtggag caacacaagc atcagaggaa gtcaatggcc
    77461 ttggttatgt gcagcttgtt cagctaacat atgtaattaa tgagtggcat agagtcaatc
    77521 acaacatgat ctaatactca gttgacatta gtctgatagt agacatactt actgatgaaa
    77581 gtcactaaaa taagtttttg ctcattaaaa aagcttggcc tgtttcttca ggtcaagctt
    77641 tttgagatta atgctgtgtt tttgaggtct tattgtcacc tcttgtttct tgataatggt
    77701 gaagcaattt tttgaatttt ttaacggcag cgcgtgttag ctgcttagat gatttgccat
    77761 ttctgctgta aatgggattg tgcttatccc tttgctgttc taaatcggga actagaaaag
    77821 ttgcatcagg actattaatt gctttttcaa taaaagccgg atcaaaaagc agaatagggt
    77881 caatatcaag cagacggtgc aagtcatcgt tttggttgcc ataattgaaa gaagaaccat
    77941 tgacaatact atttcgcgtt aggttatcag gatctagtgc tactaaaaat tgtccagatt
    78001 ctgacaaaat aaactctgag tgaaaatgaa ttaaaatctt atagttggct tgaggaatat
    78061 tgtctgtata gactgcctga tgattgccat tagcatctaa aatactagca accttattat
    78121 ggtatctaga agattcataa agagcataat cgtcatcttc tagagtagcc aaatatttgg
    78181 ctaaggcatc cgcatcggtt ttccctttat tcccataatg tgagcgaacc cactccgttt
    78241 gctgggttga tatgaggtaa cggagttgat gaattttccg attaaaacgg ctataaggaa
    78301 tgtgttcgag attaacataa taagcctgaa tcagggtaga taattggtcc caaaaaggat
    78361 ctgttggcga tagctttgga cttaattgtg ccaatacttg ctgtgtttgt tttgattgtc
    78421 ctgtcaactc gtctggcatc tttaaatacg tcaagagcag ttgtaaccgc ttttgagctt
    78481 cttgaggcgt ctgtgccatc tcttcttgtt gccaaagctt ttgaaagtca ggtgatccta
    78541 tcaggcgaat gcgactataa agttgttcga aatgataaga gtttcctcta acagcgagtt
    78601 gttcaaggta tcctttttgg atggctttat aggaccatcc gtccttatcg agctttcgaa
    78661 cataatcaag caagtcgtgg cgtaatttaa tagcttctga aagctggagt tctcgtaatt
    78721 taggatagtt ttggtaaaaa ggtgccacta aattttgata aagtttgtgt tctttttcaa
    78781 aggcaatccg ctgatagtct ttctgccaaa aactgacgca aaaagtcaga aacatcaaga
    78841 agaatagcca ttttccaagt aatttcatag gtttttagtt gacaaacatg gcatcgccaa
    78901 agctaaagaa acgatacttt tcgtcaaccg cgtgtctgta agcttcaagg acaaagtcac
    78961 gccctgcaaa ggctgatact agcatcacaa gggttgattt tggaagatgg aaattagttg
    79021 aaaaagcatc aactaccttg aattggtagc ctggtttaat aaaaatattg gtccaacctg
    79081 aatcagcttg aatgtcccct tggaacttac ctccgatggt ttccaacgta cgaatagagg
    79141 tggttcctac agcgacaaca cgaccgccag cttgtttgac gtctcttagg gtttgcgctg
    79201 cttcttctga gagggaataa aattccgaat gcatatcatg ctcatcgagg ttatccacgg
    79261 aaacaggtct aaaagtccca agccctacat gtagggtcaa ataaaccaaa tgtacccctt
    79321 tggcttcgat ttttttgagc aagtctgttg tgaagtggag accagcagtt ggggcggccg
    79381 cagagccatt ttctttagca taaacggttt ggtatcgctc agcatcctct aatttttcgt
    79441 gaatataagg aggcaatggc atttcgccga ggctctctaa aacttctaag aaaatcccat
    79501 catagctgaa ttcaacaatt cgtccaccat gttctaattc gtcgataatg gtggctttga
    79561 gacgcccatc tccaaaattg acttggctac caaccttgag ccgtttggct ggcttggcta
    79621 aaacttccca ttgatctcct tgtgtatttt taagcaaaag caattccaca tgaccatgag
    79681 tatcgggttt ttctccataa agtctggcag gcaagacacg ggtgttattc atgacgaggg
    79741 catcccctgg atttaattga tcaatgatat ggtcaaaatg gctatcaacc atagtttttt
    79801 gacggtgatc aataatcaat agttttgaac tgtctctttt ttcgagtggg gtttgggcaa
    79861 tcaattcttc tggtaactca aaatcaaaat cgttagtatt cattgggact cctttaaagc
    79921 cactagtaaa tctcttccta gtaactcttt catgtaagat aaatcttttc tattatatca
    79981 cttgtcgtct aacccgtcat ctttaatctt tcatcagaaa gtaaaggata ggcttgacaa
    80041 aaattggtat ataccatata ataaaaacac gaaaggtcta taccaattag aaaaggagaa
    80101 tgacatgaaa attattcggg tccaagatca gattgaaggt gggaaaatcg cttttacctt
    80161 attgaaagat agcttagcta agggagctaa gacgttagga ttagcaacag gaagttcacc
    80221 aattagtttt taccaagaaa tggtcaaaag tcctttggat ttttcggact taacaagtat
    80281 taacttggat gaatatgtcg gtctttcagt agagagcgat cagagttatg attattttat
    80341 gcgtcaaaac ctttttaatg cgaagccttt taaaaagaat tacttgccca atggtttagc
    80401 aactgatatc gaagctgaag ctaaacgata tgaccaaatc attgcagagc atccgattga
    80461 ttttcaagtg cttgggattg ggcgtaatgg gcacattggt tttaacgaac ctgggacctc
    80521 ttttgaagaa gaaacgcatg tagtggatct tcaggaatca actatcaaag ccaatagtcg
    80581 tttctttaca agtattgagg atgtgccaaa acaagctatc tctatgggaa ttgcctccat
    80641 catgaagtcc aaaatgattg ttcttcttgc ctttggacaa gaaaaagctg atgcgatcaa
    80701 gggaatggtt tttggaccaa tcacagaaga cctcccagca agtattctcc aaaaacatga
    80761 tcatgttatc gtcattgtgg atgaagctgc tgcgtcacaa ttagattaac ctaaccagtc
    80821 gttaaacctt gtaagaacaa aaatgaggag atagtcaacc tcatttaaga agaagtcttg
    80881 taacttctat ttcttttgca agggtaaatt tatgttacac tactaatatg cgtttagata
    80941 aattattaga aggtacaaaa gttggctcta gaagtcaagt gaagaaactg attaaggctc
    81001 aaggggtttg ggttgatcac atgcctgcca gaaatggtcg acaaaatgtt gatcctggct
    81061 tgcaactgat tgaggtgact ggacagcgag tgacgcatcc taaacattcc tacattatcc
    81121 tcaacaagcc atcaggggtg gtctcagcta agaaagatac taactattta accgttattg
    81181 atcagcttgc tgaagaagat aaaagtccag acttgtatcc tgttggcaga ttggatagag
    81241 ataccgaagg gttggtttta ctcactgata atggtcccct agggtttcgg atgttgcacc
    81301 ctattcatca tgtttctaaa acgtatcttg taaccgttaa tggcttgtta gcagaagatg
    81361 cctcagattt ttttgcagct ggtatttgtt tcccaacagg tgaacaatgt caaccagctc
    81421 aattgactat tcttaaagcc gacacagacc agtcacaggc tagtttgacc atttcagaag
    81481 gaaaatttca ccaagtgaaa aaaatgtttt tgacctatgg tttgaaagtg acctctctga
    81541 aacggacgca ctttgcagga ttggaactcg gtcatttagc cagcggagaa tatcgttatc
    81601 taacagcgtc agaaaggcaa ctcattaaaa cgtatctaga ctgagcaaaa catgctttca
    81661 aaaagaagct attcttgctt aatcaataaa gtgtccattg actattatag tcatgatgag
    81721 tccgactttt gctatgttta gtcatcttgt tgttacaaaa tcaggtaagc aaaaaaattc
    81781 aattcccact gtctccttaa cctgaagcgt tataaaaacc cttgtgttaa actctcataa
    81841 attggaaatg ggagtgtttt ttgatggcta aaaaaactaa agctacttaa agtttggtac
    81901 ttagttttcg aataataagg tggaagatct aataggaggt gacaaaaata ttaaccgctt
    81961 tagatggtaa gaatcagctc atttcgctag taactcagcc tatttcaacg aaaccgcctt
    82021 tttgttgccc agcttgcaaa tctcctgttc gcttgcgtca ggggacaatt agacgacctc
    82081 attttgccca tgtacaacta gctcattgtc aattccaagc agaaaatgaa tctgaggaac
    82141 atttgacgtt gaaggcaaaa ctttacacca gtttagtccg aacagaagct gtctgtattg
    82201 aaaaatatct tcctgagctg caacagatag cagacctttg ggtgaatgat aagttagcct
    82261 tagaaattca gtgcagtccc ttgccagtgg agcgtctaaa gaaacgcacc aaagcctatc
    82321 aagaaaaggg gtatccggta cgatggttac tgggaagaaa attgtggctt aacactcact
    82381 taactgcttt gcaaaaacag tttctttact tttcatctag tttgggcttt catttgtggg
    82441 agctggatgc agctgcaaat ctgctacgtc tcaaatattt aatccatgaa gacttatttg
    82501 gtaaggtaag ttatctaacc aaaaccattt ctttagacca caatattatg gaaatgtttc
    82561 gattacccta tcagcaagaa atcctttatt cttatcagaa aaaaatgact gtgaacctat
    82621 ctaaaagaat acaaagagct cttttagcta gacacccgaa atggctacga cgacaagaaa
    82681 aggcttactt atcaggctat aatttactta tgttaacaac tgatgctttt tatcctcaat
    82741 ggagaccagt tcaatcttcc agcggttttt gtcaaattaa aggaaatctt cgcccttatt
    82801 atgaaagttt taaagtctat tataaaaaag aaaaggataa gaaggtgcaa acgctttttt
    82861 caccaaaata ttatgttaaa atggatagta atagaaaatg agaaggagat gttatgactg
    82921 ataatcgcag ccatttagaa gaaaaataca cttgggattt gagcactatt tttgcaacag
    82981 ataaggattg ggaagctgaa gtcagtgact tagctactga aattgacgcg gctaaggatt
    83041 tttcaggtca tttactagat tctagcgcta atctgttgac aattacagat acttatttag
    83101 agttagctcg tcgtgttgag aaagtctatg tttatgctca catgaaaaat gaccaagaca
    83161 ctactgttgc caagtatcaa gaataccaag ctaaggcttc aggcttgtat gcaaagttta
    83221 gcgaagtgtt ttcattctat gacccagaag ttatggcatt gagtcaggaa gattaccaag
    83281 cttttcttgc ggaaacacct gatttaaaaa ggtatcatca tttctttgac aaattgttcc
    83341 agacacgtga ccatgtgctc agccaggctg aagaggaatt attagcagga gcccaagaaa
    83401 ttttcaacgg cgctgaagaa acctttagta ttcttgataa cgctgatatt gtctttccag
    83461 tagttaaaaa tgataagggg gaagatgttg aattaaccca tggtaacttc attagcctaa
    83521 tggaatctaa ggaccgtagc attcgccaag ctgcttatga agccatgtat agtacttatg
    83581 aacagttcca acatacttac gctaaaacct tgcaaaccaa tgtgaaagtg caaaactata
    83641 aggcgcgtgt tcataaatac gattcagcac gtcaagctgc catggctgct aactttattc
    83701 cagaagctgt ttacgatacc ttgttagaaa cggttaataa acatttgcca ctcttacacc
    83761 gttatttgaa attgcgtcaa gaggttcttg gtttagacga tttgaagatg tatgatgttt
    83821 acacaccatt atctgaaaca gatttagcca ttggttatga tgaggctttg gaaaaggctg
    83881 agaaggtttt ggctgttttt ggtaaggatt acgcggatcg tgtacatcgt gcttttaccg
    83941 aacgttggat tgatgttcac gtcaataaag ggaagcgctc tggggcttat tcaggtggtt
    84001 cctatgatac caatgccttc atgctgttga actggcaaga tacacttgat aatctttaca
    84061 cacttgtcca cgaaacaggc cacagtttgc attctacttt cactcgtgaa acacagcctt
    84121 atgtgtatgg ggattatagt atcttcttgg cagaaattgc atccacaacg aatgaaaaca
    84181 tcatgacaga agctctctta aatgaagtgc aagatgagaa agaacgcttt gccattttaa
    84241 accattacct cgatggtttc cgtggaacag ttttccgtca aacccaattt gctgagtttg
    84301 aacatgccat tcatcaagct gatcaaaaag gagaagtgtt aacaagtgaa taccttaacc
    84361 agctatacgc tgatttaaat gaaaaatatt atggtttaag taaaaaagat aatcatttta
    84421 ttcagtatga atgggcacgt attcctcatt tctattacaa ttattatgtt taccaatatg
    84481 caacagggtt tgcagctgca agctatttag cggataagat tgtgcatggc acacaagatg
    84541 atatcgatca ttacttggcc tacctcaagt caggaaattc tgattaccca cttgaagtga
    84601 ttgctaaagc aggcgttgat atggcaaaag gtgattattt ggaagctgcc tttaaagtct
    84661 ttgacgaacg tctaacagaa cttgaagtac tcgtgtccaa aggcatacac aaaagctaaa
    84721 atcacaaaag tcaaggacaa aaagagttta ggattgatag aaatggagat tcacagttgg
    84781 tgtgaatctc catttctatc ggtcattttc tttttatatt ttagtggatt atcagtcctg
    84841 aaaagcaggc ttcattgacc ttagtttgac ggtttctttt ttgtcttttt tattgtgtgg
    84901 tcactcactt aaataaaacc aatagttgag taaggcgctt cagattaacg ccattccatt
    84961 gttttagaga taacgttcgt ataaaacgtg tttttattat atttgacatt ttataaaaga
    85021 gataatagaa ttaaaatact aacatttatg ttttttaaaa aataaacgtt cgtataataa
    85081 aaaaggagtt ttttatggaa aaaacaaaac gttatatcat tgcaacagca gggatacttc
    85141 tccacttaat gttgggatcg acctatgctt ggagtgttta tcgtaatcca attttacaag
    85201 agaccggttg ggatcaagct cctgtcgctt ttgccttttc tttagctatt ttttgtttag
    85261 gtttatctgc tgcttttatg ggaaatttag ttgaacaata tggtcctcgt ctaaccggaa
    85321 cggtgtcggc tattctttat gcttctggaa atatgctgac tggtttagcg attgatcgta
    85381 aagaaatttg gcttttatat attggttatg gtgttattgg tggcttagga cttggagcgg
    85441 gatatatcac accgatatca actattataa aatggtttcc agataaaaga ggcatggcaa
    85501 cagggtttgc tattatgggg tttggttttg cgtctttatt aacaagtccg attgcccagt
    85561 ggctaattga aacagaaggt ttggtagcaa cattttacct tttagggctg atttatctaa
    85621 tagttatgct ttttgcttct caattgataa taaaaccaac tgctgctgag atagctatac
    85681 tagataaaaa aagattacaa aataacagtt atttaatcga aggaatgacc gctaaagaag
    85741 cacttaaaac aaaatcattt tattgtcttt gggtaatttt atttatcaat atcacatgtg
    85801 gcttaggact tatctcagtt gttgcgccaa tggcacaaga tctaactggt atgagtccag
    85861 aaatgtcagc aattgtggtt ggtgctatgg ggatttttaa cggtttcggt cgtttagtgt
    85921 gggccagttt gtcagactat attggacgcc gtgtgacagt aatactttta tttttagtaa
    85981 gcataattat gactattagt ttaatatttg cacatagttc cctaattttc atgataagca
    86041 ttgccaccct tatgacttgt tatggtgcgg gtttttctct cattccgcct tatttaagtg
    86101 atctttttgg ggcaaaggaa ctggctacat tacatgggta tatattgaca gcttgggcaa
    86161 tagctgcatt aactggacct atgttattat ctatcactgt tgaatggact cataattatc
    86221 ttcttacctt atgtgttttt attgtcttat acattttagg attaatggta gcattaaggt
    86281 taaagaaatg atgtcctata aaaaatttaa aagtaaaccc tagcaaagcc tagggttttt
    86341 ttatataatt aggtttatgg ttaaatcata cagtaaaaca gcaaatcata atatgcgtcg
    86401 tcctgttgtc aaagaagagc ttgttcatta tatgcgaaca cggcagaagc aaatcacagg
    86461 ttttttagca gagttagagc aattcgcaag acaagaaaac attcctatta ttcagcctga
    86521 ggtcgtggct tatttcaggt ttttattgca aagcttacag ccaaaacaca ttttggagat
    86581 tggcacagcc attggttttt ctgcgctttt aatggctgaa aatgcaccag atgcgacgat
    86641 tgtgactatt gatcgtaatc gagagatgat cgattttgct aaagcaaatt ttgctaagta
    86701 cgacagtcgc caacagatcc gcctgttaga aggagatgca gcagatatat tatctacact
    86761 tgaaggaaat tttgactttg tgtttatgga ttccgccaaa tccaaatata ttgtctttct
    86821 accagagatt ttaagactgt taaaagtcgg tggtgtagtc attttggatg atgtctttca
    86881 aggaggtgac attacaaaac cgatcgaaga cattcgacga ggtcagcgta ctatttatcg
    86941 tggcttacag tctttgtttg atgctacctt aactcatcca aacctaacaa ctagcctggt
    87001 ccctcttagt gatggattat taatgattcg taaaaatcaa gcagatattc tattaccaga
    87061 ttaagtaaca ttgataaatt tatgttataa taaattagtt aaagataaaa aggagctcag
    87121 aagtaaatga aaaactcaaa taaactcatt gctagtgttg tgacattggc ctcagtgatg
    87181 gctttagcag cttgtcaatc aactaatgac aatactaagg ttatttcgat gaaaggtgat
    87241 acaattagcg ttagtgattt ttacaatgaa acaaagaaca cagaagtatc gcaaaaagcg
    87301 atgctaaatc tggtaattag tcgtgttttt gaagctcaat atggtgataa ggtttcaaaa
    87361 aaagaagttg aaaaggcgta tcataaaaca gctgaacagt atggcgcttc attctctgct
    87421 gctttggcac aatcaagctt gacacctgag acttttaagc gtcagatccg ctcttcaaaa
    87481 ttagtagaat atgcggttaa agaagcagct aaaaaagaat tgacaacaca agaatataag
    87541 aaagcatatg aatcttatac tccaacaatg gcagtcgaaa tgattacttt agataatgaa
    87601 gagacagcta aatcagtctt agaggaacta aaagccgaag gcgcagactt tacagctatt
    87661 gctaaagaaa aaacaacaac acctgagaaa aaagtgacct ataaatttga ttcaggcgcg
    87721 acaaatgtac cgactgatgt cgtaaaagcg gcttcaagtt tgaatgaggg tggcatatca
    87781 gacgttatct cggttttaga tccaacttct tatcaaaaga agttttacat tgttaaggtg
    87841 actaaaaaag cagaaaaaaa atcagattgg caagaatata agaaacgttt gaaagctatc
    87901 attatagctg aaaaatcaaa agatatgaat ttccaaaaca aggttattgc aaatgcattg
    87961 gataaagcta atgtaaaaat taaagacaaa gcttttgcta atattttggc gcaatatgca
    88021 aatcttggtc aaaaaactaa agctgcaagt gaaagttcaa caaccagcga atcatcaaaa
    88081 gctgcagaag agaacccatc agaatcagag caaacacaga catcatcagc tgaagaacca
    88141 actgagactg aggctcagac gcaagagcca gctgcacaat aagtaggatt ttattgacta
    88201 atcagttaaa aaaacttata ataatttagt taagaattgt ttatcaagga ttagatacag
    88261 aaaagtgacg gttgctgcga gtcattgata attagataaa catgctactt aactttacaa
    88321 caattgatat cgtaaattaa gaatgacaag ttcattgaat agaggtggta ccgcggtttt
    88381 cgccctctgt gagatggact tgttttgtat tgaggactat ttgaaatcaa cgaaaggaat
    88441 agagtagact aggctgccag gcttatagct gatctcctag caagaaagac gagctgtgtc
    88501 aactggtgtg attacattac tagcttcagc ataacactgt ttttcttact ctttgtatct
    88561 aaatttttat gaaagaatta tcgtctgcac aaatccgcca aatgtggttg gatttctgga
    88621 aatctaaagg acattgcgtt gagccttcag ctaacttggt tcctgtgaat gacccaacgc
    88681 ttctttggat caactcaggt gttgcaacct tgaaaaaata ctttgatggt tcagtgattc
    88741 cagaaaatcc acgtattacc aatgcacaaa aatcaattcg tactaatgat attgaaaatg
    88801 ttggtaaaac agcacgtcac catactatgt ttgaaatgct tggtaacttc tcaattggag
    88861 actatttccg tgatgaagct attgagtggg gatttgaact cttgacaagt ccagactggt
    88921 ttgatttccc taaagataag ctctacatga cttattaccc agatgacaag gattcatata
    88981 accgttggat tgcttgtggc gttgaaccaa gtcacttggt gccgatcgag gataacttct
    89041 gggaaatcgg tgctggtcct tcaggtccag atacggagat tttcttcgat cgtggtgaag
    89101 atttcgatcc agaaaatatc ggacttcgcc tcttggctga agatatcgaa aacgatcgtt
    89161 acatcgaaat ctggaacatc gttctctcac aattcaatgc tgacccagcc gtaccacgtt
    89221 cagaatacaa agaattacca aacaaaaaca ttgatacagg tgctggtctt gaacgtcttg
    89281 cagctgttat gcaaggggca aaaacaaact ttgaaactga cctcttcatg ccaatcatcc
    89341 gtgaagtaga gaagttgtca ggtaaaactt ataatccaga tggcgacaac atgagtttca
    89401 aggttatcgc tgaccacatc cgtgcgcttt catttgctat cggtgatggt gcgcttcctg
    89461 gaaatgaagg tcgtggttac gttcttcgtc gtcttctccg tcgtgctgtt atgcatggtc
    89521 gtcgtcttgg catcaacgaa actttccttt acaaattggt tccgactgtt ggacaaatca
    89581 tggaaagcta ctacccagaa gtgcttgaaa aacgtgattt tatcgagaaa atcgttaaac
    89641 gtgaggaaga aacatttgct cgtactatcg atgcaggtag cggtcactta gattcattgc
    89701 ttgcgcagct taaggctgaa ggtaaggata ctcttgaagg taaagatatc ttcaaacttt
    89761 atgatactta tggattcccg gttgaattga cagaggaatt ggcagaagat gcaggctaca
    89821 agattgatca cgaaggcttt aagtcagcca tgaaagaaca acaagaccgt gcgcgtgcag
    89881 ctgttgttaa gggtggttca atggggatgc aaaatgaaac cctagctggt attgttgaag
    89941 aatcacgatt cgaatacgac acatatagtc ttgaatcaag tctttcagtc atcatcgctg
    90001 ataatgaacg taccgaagct gtttcagaag gtcaagctct tcttgtcttt gctcaaacac
    90061 cattctatgc tgaaatgggt ggacaggttg ctgacacagg tagaatcaaa aatgataagg
    90121 gtgacacagt tgctgaggtt gttgatgttc aaaaagcacc aaatggtcaa cctctacaca
    90181 ctgtaaacgt tttggcatca ctttcagttg gaacaaacta cacacttgaa atcaacaaag
    90241 agcgtcgttt ggctgttgag aaaaaccaca cagcaactca cttgcttcat gcagcccttc
    90301 acaatgttat cggtgaacac gcaactcagg ctggttcatt gaacgaagaa gaattcttgc
    90361 gctttgattt tactcacttt gaagcagtaa gcaatgagga acttcgtcac attgaacaag
    90421 aagttaatga gcaaatttgg aacgctctta cgatcacaac gactgaaact gacgttgaaa
    90481 ccgcaaaaga gatgggagca atggcacttt ttggtgagaa atatggtaaa gtggttcgtg
    90541 tggttcaaat tggtaattat tctgttgaac tttgtggtgg aactcactta aataattctt
    90601 cagaaatcgg tctcttcaag attgtcaaag aagaaggtat tggttcaggc actcgtcgta
    90661 ttattgcagt tactggtaga caagcttttg aagcttatcg taaccaagag gatgccctaa
    90721 aagagatcgc tgctactgta aaagctccgc aattgaaaga tgcagcagct aaagtacaag
    90781 ctcttagcga ctcacttcgt gatcttcaaa aagaaaatgc agagcttaaa gaaaaagcag
    90841 cagctgcagc agctggtgat gtctttaaag atgttcaaga agctaagggc gtgcgcttca
    90901 ttgctagtca agttgatgtt gcagatgcag gggcacttcg tacatttgct gataactgga
    90961 aacaaaaaga ctactctgat gtgcttgttc tcgtagcagc tattggtgag aaggttaatg
    91021 tccttgttgc aagcaaaact aaagatgtcc acgctggtaa catgatcaaa gaattggcac
    91081 caattgtagc aggtcgtggt ggaggtaaac cagacatggc tatggcaggt ggtagcgatg
    91141 caagtaaaat tgcagagctg ctagcagcag ttgctgaaac agtgtaaatc cataaaaaac
    91201 caagttattt agaacttggt tttttatatt tgaaatgact accatcataa cctttttgac
    91261 tattatcgtt gtcaaaaaga aaaagatatg ttacaattat agtaacaaat agacatgagg
    91321 aggtgttaga gaaaatgaca catggtatca aacttaagag gcagatttgc ttatgggcaa
    91381 gtatcctgac tcttttcatt ttaagttatc atcttatcag ggtaatctgg tttggagtac
    91441 ccttgagtta tctggttttg ggctttacag gactagcctt gctgttgaat actttttctt
    91501 attttagaaa gtaagttata agttaaagaa gaatgaagga gatggcaatg gaggttattc
    91561 ttaaaaatcg gctcaaagaa ttacgagcca gagatggaat taatcaaacg gaaatggcta
    91621 aactggcagg agtatcgagg cagaccatca gtctcattga gcgtaacgag tacaccccat
    91681 cagttataat tgccatgaaa attgcaaagg tatttcagga accagttgaa gaggtgtttc
    91741 gtctagtgga ggtcgaggaa tgaaaaagaa gaagaatagt tttttacgct tgttaaaaat
    91801 gttattgcta tcaagtttgg cgggagggat tataggtggc atggttggag cctttttagg
    91861 ttaccatgga gagagattag atcagctcac gttcctaaaa gatgatgtga ttaacctgat
    91921 tatcttatta aatcgtctag tagttgtcac aggcctcaca ctttcctttg tttttttaac
    91981 gcaactgaaa aaagagacag ctgtttataa cacaattgaa gaggatgatt attctgaaaa
    92041 tggttaccgt cagctgaata aaaagcatgc ttataccatg ttattgattg ccgtagcttc
    92101 tattttatcc atgtgcaatg tgctacttgg tctgacctta actaatgatt cacagcatgc
    92161 catgctggcc attccgcttc tggatatcct tttattatta atggtcattc cttttcaagc
    92221 tttagccatg aaacgttaca atgccattcg gggaaccgat gttccttatt ttccaaattt
    92281 gaaagaatta aaacataata tcatggctct agatgaggca gagttacaag cctatcataa
    92341 gacatcgttt gaaagtgtgt tgtcattaaa tggagtcatc atcccttcct tgtatgtgat
    92401 tttatttttt gtctatctat tcactggtca agtggagtta acagccatct tagttttggt
    92461 gttaattcag ctctatttac tcgttaagag tgcaacaatg accagacaat tttaccgtta
    92521 gcctaaaagg agactgttta tgaaaggatt cattaattat ttaaaaatag cagtgctcat
    92581 tattctggct atggttttca atgtccttcc gatgatttta ttgcaaaagc aacacgatat
    92641 tcctatggtg cttaattggg gaattggtat tttctacttg gttattgttg gaagtgtcct
    92701 tattgtatta tggcgtcttt atcaagctaa gcaagacacc cctattaaac agcaaaaaat
    92761 gagattggtt gactggggtt atttagcatt attttggtta atcatccgtg tgatagctat
    92821 tgcaggtacc cttgttaacc agctatggtc tggtcaacaa gtgagtgcta atgatgctgc
    92881 aatacatacc ttagctagac ttatcaaagg tggtttcccg ctttatactg ccctatttgt
    92941 acttgtgata gcttttatcg ctcctattat ggaagaacta gtctttagag gatttcctat
    93001 gattgatctc ttcaaaggaa aatcacttaa ggtggcaggt ttagtgacct ctcttgtttt
    93061 tgctttacca catgccacca atagtgttga atttatcatg tacagctgta tgggcatttt
    93121 tctctttgtt gcctatcaaa gacgaggaaa cttaaaagac gctatcttgt tacatatttt
    93181 taataacttg attgaagtca ttttgttaat gtcaataggc ttaggagtca tataataaaa
    93241 agcttcggat ggatgaactg caccccaaaa gttggacaaa aaaatctaac atttgggttg
    93301 gaattgtcaa gaaaaaatag acataaagtt aagctaatga gtaactattt ttttcaaatt
    93361 caacaggtga gagataccct aaagctgaat gcagacgttt ggggttatag taagtctcac
    93421 tatatttaaa aatctcaagc ttagcttgct caatagttgc gaaatgagca tcattgacaa
    93481 gctctctttt taatgtttta taaaaggatt ccatgagtgc attatcgtat ggattacctt
    93541 ttcgactcat cctggactta cattttttcc atctaagtag gtcctgaaat cgtgctccgg
    93601 tatattgaga accctgatct gtatggacga ttaccccttc tttaggcttt tctctattat
    93661 aagcttgatt gaaagcttct gttaccaact tgtcttgcat acgttggccc attgcccaac
    93721 caacaa
//
LOCUS       DATWEK010000004        82585 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.004, whole genome shotgun sequence.
ACCESSION   DATWEK010000004 DATWEK010000000
VERSION     DATWEK010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 82585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82585
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.004"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            221..1780
                     /locus_tag="VCR92_000330"
     CDS             221..1780
                     /locus_tag="VCR92_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEP4267427.1"
                     /translation="MIELNDEFIRKETIELANDGPRVHTTQYETKVPRLHKCYLLFFS
                     IIISSLTIAVPFLTDAANGLQSQNLYIGMMLTKGQLPYSDAFTTGGLFYFVIIALSYY
                     LGSTLWLVFVQVFCFYLSGLYLYKLINYMTCFQKVALTFSISYYLLSVSLGFGGLYPT
                     QLAMPFILISAWFLTKYFACLVKDEAFILFGFVGALAMLIDPSTLIFWSFACVTVFSY
                     NISQKHLARGFYQLLASIFGMILVFYTAGYFILNLQVLNPYLSQTMIYPFTFFKSGNL
                     SLLFGLAIQLFFALGLGLLTGMGNVIRRFKNNSDRVVKWLFVMVILESILVAIFSQDY
                     RPYHLLPLLPFGLILTAIPVGYQYGIGLGQSSHRRRHGKNGVGRVMMIYLKRHFYLPI
                     LIVGTILICSTYCFISSIPLNQERDHIASYLEQKLNKTQSIYVWDDTSKIYLDSKAKS
                     VSQFSSPDINTQKASHRKILEDELLENKAAYIVVNRYKNLPKIIQKVLSTNYKVDKQI
                     TTKSFIVYQKK"
     gene            1877..4075
                     /gene="nrdD"
                     /locus_tag="VCR92_000331"
     CDS             1877..4075
                     /gene="nrdD"
                     /locus_tag="VCR92_000331"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEP4267428.1"
                     /translation="MVSLEEDKVTVQPDIKVIKRDGRLVNFDSTKIYSALLKASMKVT
                     RMSPLVEAKLEAISDRIIAEIIERFPTNIKIYEIQNIVEHKLLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLINKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKM
                     LPSHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAKKWIVETKRESYAF
                     EKTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIDLTG
                     SFKSPMGCRSFLQGWKDENGQDVTSGRMNLGVVTLNLPRIAMESNGDMDKFWELFNER
                     MLISKDALIYRVERVTEAKPANAPILYQYGAFGKRLEKTGNVNDLFKNRRATVSLGYI
                     GLYEVASVFYGGQWEGNPDAKAFTLSIIKAMKQACEDWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTEKFGIVTDITDKEYYTNSFHYDVRKSPTPFEKLDFEKDYPEAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYNCQFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGL"
     gene            4257..4403
                     /locus_tag="VCR92_000332"
     CDS             4257..4403
                     /locus_tag="VCR92_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267429.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSKKKTDKKSRVQELKARFLEKSK
                     KQDN"
     gene            4432..5367
                     /locus_tag="VCR92_000333"
     CDS             4432..5367
                     /locus_tag="VCR92_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEP4267430.1"
                     /translation="MLNIGIVGLGAISQKAYLPYMRQLSDITWHLSTRNAAVRQQVGQ
                     LFGHAILYSDVKELSKASLDGVFIHAATSAHAELASLFLNQGIPVFMDKPIADNYLMT
                     KNLYDLAKENQTFLMAGFNRRFTPRVKKLSSLSTKRKVAVEKNDLNRPGDMTFKLFDF
                     FIHPLDTALFLSEGTLLKGHFQYHLEAGLLSQVMVTLMTESMTTTASMNLQSGSRREV
                     MEVQRAEETYHLENLDELSIYKGTEKRVLGFASWDTTLHKRGFETMIDAFLEAISTGV
                     NPVSPESSLLSHWICQQIADSQLSYGELTVELPKD"
     gene            5376..5885
                     /locus_tag="VCR92_000334"
     CDS             5376..5885
                     /locus_tag="VCR92_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP4267431.1"
                     /translation="MEIRRPTLKDKDAVLSMINEFLEQKSATDGLWHFNVNDFNYETW
                     LEDSLRQEMGLSSQGVPAIQYVAFDERSQAIGFLNLRLRLNERLLEKGGHIGYSVRPS
                     QRGKGYAKEMLKQAVSYAISKNITTILVTCDETNVASRAVIVANGGVLEDSRGGTERY
                     WIEEQRGDK"
     gene            5885..6499
                     /gene="nrdG"
                     /locus_tag="VCR92_000335"
     CDS             5885..6499
                     /gene="nrdG"
                     /locus_tag="VCR92_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEP4267432.1"
                     /translation="MAEKCWNNPKPKEWQAEELSQGRIIDYKAFNFVDGEGVRNSLYV
                     SGCLFHCKGCYNAATWSFKAGMPYTQELEEQIMTDLAQPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRRELPEKDIWSWTGYTWEEMMLETPDKLEMLSLIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVQKSLAAKEVIIWDKLNDGDQTFEQISREDLL"
     gene            complement(6673..7404)
                     /gene="yaaA"
                     /locus_tag="VCR92_000336"
     CDS             complement(6673..7404)
                     /gene="yaaA"
                     /locus_tag="VCR92_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEP4267433.1"
                     /translation="MLTFLIPTAKEMMIPKESHPHLLPQDSQAILKIMAAMTTEDLAK
                     SYRIKEEAAKKEQQRWQDMASQQNLAYPAYQLFNGLMYRHIKRDKLTTQEQAYLTQQV
                     YITSSFYGIIPANHPIAEHRHDFHTRIKIEGQSLKSYWRPCYNQFAKEHPQVISLLSS
                     EFDDVFSKDCKQLWISPKFMAEKEGQFKTHSTISKKARGAFLTACMENNCQTVDSLKS
                     LVFAGFYYHPDLSTDHEFVYIKKEA"
     gene            complement(7446..8303)
                     /locus_tag="VCR92_000337"
     CDS             complement(7446..8303)
                     /locus_tag="VCR92_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEP4267434.1"
                     /translation="MTYPYNSTISLGTVSLNVTDLAKMTTFYTSIIGLQVLSQDTTSR
                     QLTTDGKTVILELRQTPLPANKAYGLYHTSFLVPDRHSLGLVLNHFLTRGISLEGSAD
                     HGYSEAIYLSGPEGNGIEIYHDKAVEHWDIRDNGQIIGVTEPTDTKSILEQLTDIPKR
                     FLLAQDTRIGHVHLSVKNALASSLLYQKVFDLGDKMTIPSASWIASGNYHHHLAFNHW
                     SAPYLKKHQEGAPGLAFLTIHIETPLLFSATLKKARLHGLAILQEDSSSFTTEDEEGI
                     CVNVILGQD"
     gene            8490..8827
                     /locus_tag="VCR92_000338"
                     /pseudo
     CDS             8490..8827
                     /locus_tag="VCR92_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018307.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(9106..9819)
                     /gene="treR"
                     /locus_tag="VCR92_000339"
     CDS             complement(9106..9819)
                     /gene="treR"
                     /locus_tag="VCR92_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEP4267435.1"
                     /translation="MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVR
                     KALSLLTKAGLILKKQGRGTQVIKHHQIMFPISELTSYQELVSYSNLDSKTNVIAIDK
                     LIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
                     QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTE
                     SRHKLEKFKFLDFARRRPK"
     gene            10030..12054
                     /gene="treP"
                     /locus_tag="VCR92_000340"
     CDS             10030..12054
                     /gene="treP"
                     /locus_tag="VCR92_000340"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEP4267436.1"
                     /translation="MGKFEQDAKSLLTAIGGKENIKAVTHCATRMRFVLNDNNKANVK
                     EIEKISVVKGTFTNAGQFQVIIGNDVPVFYNDFTAVSGIEGVSKEAAKSAAKSNQNAL
                     QQVMTMLAEIFTPIIPAIIVGGLILGFRNILESVPFEFLGQQVEKGKLVFDAAGDPVW
                     NTIVRVSPFWSGVNHFLWLPGEAIFHFLPVGITWSVTRKMGTTQILGTVLGICLVSPQ
                     LLNAYAVAGTPAAEIAKNWVWDFGFFTINRIGYQAQVIPALLAGLSLAYLEIFWRKRI
                     PEVVSMIFVPFLSLIPALILAHTVLGPIGWTIGKGISFVVLAGLTGPVKWLFGAIFGA
                     LYAPLVITGLHHMTNAIDTQLIADTATRTTGLWPMIALSNIAQGSAVFAYYLMNRHEE
                     REAEISLPAAISAYLGVTEPALFGVNVKYVYPFVAGMIGSGIAGLLSTTFNVQANSIG
                     VGGLPGFMAINVKYMIPFFICMVVAIVVPMFLAFFFRKSHIMTKTEDEAKLPETPVSD
                     APVATAPHKTMQGTVITLTSPLTGEVKALSEAVDPVFAQGVMGQGALLQPTEGVLVAP
                     CDAEVSVLFPTKHAICLVTTEGLELLMHIGMDTVNLDGQGFEALVKQGDQVKAGQTLI
                     QFDIAAISEAGYATETPLVVTNQDAFTVTVEGSLPRQIKANDKLAVAMKK"
     gene            12122..13750
                     /gene="treC"
                     /locus_tag="VCR92_000341"
     CDS             12122..13750
                     /gene="treC"
                     /locus_tag="VCR92_000341"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEP4267437.1"
                     /translation="MTIDKKKVVYQIYPKSYKDTTGNGVGDLRGIIDKLPYLQELGID
                     MIWLNPFYPSPQRDNGYDVSDYTAVNPDFGTMADFEDLVKAAKEHQIELMLDMVLNHC
                     STDHEWFQKALAGDPYYQDFFILRDQPTDWVSKFGGNAWAPFGDTGKYYLHLFDVTQA
                     DLNWRNPHVREELAKVVNFWRDKGVKGFRFDVINLIGKDEELVDCPVNDGKPAYTDRP
                     ITHTYLHDLNQASFGQDDSFMTVGEMSATTIDNCLLYTAPEREELSMAFNFHHLKVDY
                     ENGQKWTIMAFDFAALRDLFHAWGEGMSQGNGWNALFYNNHDQPRALNRFVDVTHFRN
                     EGATMLAASIHLSRGTPYIYMGEEIGMLDPDFDSMDDYVDVESLNAYSSLLVSGKSAE
                     EAFAIIKAKSRDNARTPMQWDASEHAGFTTGKPWLEVGKSYRDINVETEKEGRIFPFY
                     QRLIALRKELPIIAEGDYRAAFKDSQAVYAFERHLGDQCLLVLNHFYAGEVELELPPR
                     YQHGQALISNYEKVSICEKVMLKPYQTLAILADN"
     gene            13958..15853
                     /gene="pepO"
                     /locus_tag="VCR92_000342"
     CDS             13958..15853
                     /gene="pepO"
                     /locus_tag="VCR92_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEP4267438.1"
                     /translation="MTTYQDDFYQAVNGKWAETAVIPDDKPRTGGFSDLADEIEALML
                     DTTDAWLAGDHIPDDAILKNFVKFHRLVADYAKRDEVGVSPILPLIEEYQSLKSFSEF
                     VANIAKYELAGLPNEFPFSVAPDFMNAQLNVLWAEAPSILLPDTTYYEEGNEKAEELR
                     GIWRQSQEKLLPQFGFSTEEIKDLLDKVIELDKQLAKYVLSREEGSEYAKLYHPYVWA
                     DFKKLAPELPLDSIFEKILGQVPDKVIVPEERFWTEFAATYYSEANWDLLKANLIVDA
                     ANAYNAYLTDDIRVESGAYSRALSGTPQAMDKQKAAFYLAQGPFSQALGLWYAGQKFS
                     PEAKADVESKVARMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDESLSLVENAQNLAKITIAHTWSKWNKPVDRSEWHMPAHLVNAYYDPQQNQIVF
                     PAAILQEPFYSLDQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLNDWWTQEDYA
                     AFKERTDKIVAQFDGLESHGAKVNGKLTVSENVADLGGVACALEAAQSEEDFSARDFF
                     INFATIWRMKAREEYMQMLASIDVHAPGELRTNVTLTNFDAFHETFDIKEGDAMWRAP
                     KDRVIIW"
     gene            complement(16019..17059)
                     /locus_tag="VCR92_000343"
     CDS             complement(16019..17059)
                     /locus_tag="VCR92_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEP4267439.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREK
                     GMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAE
                     GKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKTDEQHFGAYQHNG
                     GRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNE
                     SRAMVDKPALPFLKYGSKAQLSDDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(17193..17960)
                     /gene="rpsB"
                     /locus_tag="VCR92_000344"
     CDS             complement(17193..17960)
                     /gene="rpsB"
                     /locus_tag="VCR92_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEP4267440.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFDVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDIIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDADVAFEADIQADSIEEIVEVVEGDNA"
     gene            18264..21338
                     /locus_tag="VCR92_000345"
     CDS             18264..21338
                     /locus_tag="VCR92_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEP4267441.1"
                     /translation="MTKGIRFQLLGSPHIFLDDKEQFFAFAKANALLYYLVVNGSVSR
                     EVAASLLWENKNTQTAKKNLRNAIYQVNKVLQADVIICPNRNLLVLKKTLDIKTDINL
                     FLADPLAHLELYQGEFLQGFYLKSGEEFDLWVSKMRMQYEQVYLKACYQKIEEKLSLD
                     AIEDVEEHLKQLIERDEFEEKNYQLLMRLYQQGNCPGKVIETYYQLANVLDKELGIQP
                     SLQSQQIYQEVVAKDRNERKIKHFLRNSNHFLGRIDEIKQLENYFANCLACQEVGALL
                     LIGDTGIGKRTLARQVLANQTQTFQIVTAKCFREEAMDSLLPWRNILDGLGDLVIQNR
                     LLTTKAWKAALKRCFPVATIFQEDNNQPFIKDHTSLLVSFIVDILQHLAEIKALVILI
                     EDCHWMDEDSLTLLQRVMNQLVHYPIAFVLTKHLGTTPELGLCLNALMSQGRLESICL
                     EPFNRQESLAYINSQLGSQPVTEEEMEHLYQASQGNPFFLSEYTQTLLRHEKFVPLTP
                     AIKAKLGLKLANLSSRDDALLNYLSCCRRPIPLNTLAQLMLLPLEEVIEMVDNLGHYY
                     ILVEESVGEEVLISFRQRIIQLYSYDRLSLSKRRLLHGQIAKRLEDLLPILTPSPHLL
                     DDIAYHYQESRQVIKALEYNLNYLDATLPFQHELFPIYSKSIGSLEKSDRDHQRLMEE
                     QFDRIRQSIADLELTYDNNRDFQQLLIRFSYLEGRYDIRTGRYQEGIKNIQKVIALAT
                     ELKQPSFLLEGYRQLIHYCIQVENKPEMRYYTSLSLEAAVAANHFEAIAISLRLNGLY
                     HLIIGELNEAERLLQQSIDFFKVTPGLQANYAIQIAAALDYLGEIAQIRYQFEKAVAY
                     QKQAIALTENKPAELSVSIFYIGLGISYFYLADFEQAEQILSLAKEALVNHSYPWKET
                     QLQIYLAMIQWKKGNYQPALTLLDYRETLMSRYRNPRDKGLVFYLMAVVKYQLIFQGA
                     TLSQQEKEMADYLLSESFEYYYEIASTNLNPYRDCHLVSELNDLRQQLSAKS"
     gene            complement(21369..22355)
                     /locus_tag="VCR92_000346"
     CDS             complement(21369..22355)
                     /locus_tag="VCR92_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formimidoylglutamase"
                     /protein_id="HEP4267442.1"
                     /translation="MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFE
                     GTHFALIGFKSDKGVYINNGRVGAVKSPAAIRTQLAKFPWHLGNQVMVYDVGNIDGPN
                     RSLEQLQNSLSKAIKRMCDLNLKPIVLGGGHETAYGHYLGLRQSLSPSDDLAVINMDA
                     HFDLRPYDQTGPNSGTGFRQMFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGI
                     QFLTGQDIYQMGHQKVCRAIDRFLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPN
                     LAVLVLQHIAASGKLVGFDVVEVSPPHDIDNHTANLAATFIFYLVQIMAQHN"
     gene            complement(22541..24082)
                     /gene="hutH"
                     /locus_tag="VCR92_000347"
     CDS             complement(22541..24082)
                     /gene="hutH"
                     /locus_tag="VCR92_000347"
                     /EC_number="4.3.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ammonia-lyase"
                     /protein_id="HEP4267443.1"
                     /translation="MTRVINLDGESLTIEDVIAIARQGVACRIDDSAIEAVNASRKIV
                     DDIVSEKRVVYGVTTGFGSLCNVSISPEDTVQLQENLIRTHASGFGDPLPEDAVRAIM
                     LIRINSLVKGYSGIRLSTIEKLLELLNKRVHPYIPEKGSLGASGDLAPLAHMVLPMLG
                     LGKAYYKGELLSGQEALDKAGIDKISLAAKEGLALINGTTVLTAIGALATYDAIQLLK
                     LSDLAGALSLEVHNGITSPFEENLHTIRPQSGQLATARNIRNLIEGSQNTTVATQSRV
                     QDPYTLRCMPQIHGASKDSIAYVKSKVDIEINSVTDNPIICKDGHVISGGNFHGEPMA
                     QPFDFLGIAISEIGNVSERRVERLVNSQLSKLPSFLVKYPGLNSGFMITQYACASLAS
                     ENKVLAHPASVDSIPSCENQEDFVSMGTTAARKAFEILKNSRRIVATEIMAACQALDL
                     KPENHELGKGTKVAYDLFRKEINFIEHDKHIEIYDELNKASAVIEDPSFLEAVEQAVE
                     LSIQF"
     gene            complement(24093..25436)
                     /locus_tag="VCR92_000348"
     CDS             complement(24093..25436)
                     /locus_tag="VCR92_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HEP4267444.1"
                     /translation="MASNHMNEQEREQAKFSLSGATLYGINAVIGSGIFLLPRAIYKG
                     LGPASIAVMFGTAILTIMLAVCFAEVSGYFGKNGGAFQYSKRAFGDFIGFNVGFLGWT
                     VTIFAWAAMAAGFARMFIITFPAFEGWHIPLSIGLIILLSLMNIAGLKTSKIVTITAT
                     IAKLIPIVAFCACTLFFIKNGLPNFTPFVQLEPGTNLLGAISNTAVYIFYGFIGFETL
                     SIVAGEMRAPEKNVPRALLGSISIVSVLYMLIIGGTIAMLGSQIMMTNAPVQDAFVKM
                     IGPAGAWMVSIGALISITGLNMGESIMVPRYGAAIADEGLLPAAIAKQNQNGAPLVAI
                     LVSGAIAIVLLLTGSFENLAKLSVVFRFFQYIPTALAVMKLRKDDPDANVIFRVPFGP
                     IIPILAVIVSLVMIWGDNPMNFVYGAVGVIIASSVYYLMHGRNHQMDQMPPKEQI"
     gene            complement(25656..26252)
                     /locus_tag="VCR92_000349"
     CDS             complement(25656..26252)
                     /locus_tag="VCR92_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HutD family protein"
                     /protein_id="HEP4267445.1"
                     /translation="MTKVTIKAPSDYLQTDWSGGETNQLFLYPEDGDYKKREFSYRLS
                     KSTVALRQTTFTLLDGYHRILMTLDKPITLSDLSHAKEISLTPFEPYAFEGDTRIVSR
                     GICQDINLMYDDQYQGQLLPVWSDTPFEAPKADCQLLYALSKLTYSVTNQANQELEAN
                     HLLVIEQEASLSDLKVCPNQTSPAQTPVAVWAGLWYKT"
     gene            complement(26274..27947)
                     /locus_tag="VCR92_000350"
     CDS             complement(26274..27947)
                     /locus_tag="VCR92_000350"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEP4267446.1"
                     /translation="MVLSDIEIANSVTMEPISKVANQLGIDEEALCLYGKYKAKIDAR
                     QLVALKDKPDGKLILVTAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPV
                     FGVKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSR
                     RITWKRVVDMNDRQLRHIVDGLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKA
                     RLEKIIIGYNYQGEPVTAKDLKAGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANI
                     AHGCNSVLATKLALKYGDYAVTEAGFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRA
                     LKMHGGVPKANLATENVQAVVDGLPNLDKHLANIQDVYGLPVVVAINKFPLDTDAELQ
                     AVYDACDKRGVDVVISDVWANGGAGGRELAEKVVALAEQDNQFCFVYEEDDSIETKLT
                     KIVTKVYGGKGIRLTPAAKRELADLERLGFGNYPICMAKTQYSFSDDAKKLGAPTDFT
                     VTISNLKVSAGAGFIVALTGAIMTMPGLPKVPASETIDIDEEGNITGLF"
     gene            complement(27965..28591)
                     /locus_tag="VCR92_000351"
     CDS             complement(27965..28591)
                     /locus_tag="VCR92_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HEP4267447.1"
                     /translation="MGLVDLSLTDFAKVLGSDAPAPGGGSAAALSGANGISLTKMVCE
                     LTLGKKKYADYQAIITEIHAKSTALQASLLAAIDKDTEAFNLVSAVFDMPKETDEDKA
                     ARRTAMQKALKTAAQSPFEMMTLMVEALEITATAVGKSNTNAASDLGVAALNLKAGLQ
                     SAWLNVLINLSGIKDEDFVTDYRQKGQALLDKGCHLADDIYTKILDIV"
     gene            complement(28602..29501)
                     /gene="ftcD"
                     /locus_tag="VCR92_000352"
     CDS             complement(28602..29501)
                     /gene="ftcD"
                     /locus_tag="VCR92_000352"
                     /EC_number="2.1.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003005485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate formimidoyltransferase"
                     /protein_id="HEP4267448.1"
                     /translation="MAKIVECIPNFSEGQNQAVIDGLVATAKSIPGVTLLDYSSDASH
                     NRSVFTLVGDDQSIQEAAFQLVKYASENIDMTKHHGEHPRMGATDVCPFVPIKDITTQ
                     ECVEISKQVAERINRELDIPIFLYEDSATRPERQNLAKIRKGQFEGMPEKLLEEDWAP
                     DYGDRKIHPTAGVTAVGARMPLVAFNVNLDTDNIDIAHKIAKIIRGSGGGYKYCKAIG
                     VMLEDRHIAQVSMNMVNFEKCSLYRTFETIKFEARRYGVNVIGSEVIGLAPAKALIDV
                     AEYYLQVEDFDYPKQVLENHLLG"
     gene            complement(29589..31619)
                     /locus_tag="VCR92_000353"
     CDS             complement(29589..31619)
                     /locus_tag="VCR92_000353"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HEP4267449.1"
                     /translation="MSFYSETDIAAAMTVKLDDVLPEKTVFKEGIRRAPDRGFRLTQA
                     QTEIALKNALRYVPTKFHEEVIPEFLEELKTRGRIYGYRWRPKDRIYGKPINEYKGNC
                     TAAKAMQVMIDNNLSFEIALYPYELVTYGETGSVCANWMQYCLIKKYLEVMTDEQTLV
                     VESGHPVGLFQSKPEAPRVIITNGLLVGEYDNMKDWEIAEEMGVTNYGQMTAGGWMYI
                     GPQGIVHGTFNTLLNAGRLKLGVADDGDLTGKLFISSGLGGMSGAQGKAAEIAKAVAI
                     IAEVDQSRIETRHSQGWVTQIAESPEEALQLAQKAIDAKESTSIAYHGNIVDLLEYVN
                     DKQIHVDLLSDQTSCHNVYDGGYCPVGISFDERTRLLAEDKDTFHQMVDDTLARHFEA
                     IKTLTENGTYFFDYGNAFMKSVYDSGITEISKNGRNDKDGFIWPSYVEDIMGPMLFDY
                     GYGPFRWVCLSGKHEDLVATDKAAMEAIDPDRRYQDRDNYNWIRDAEKNQLVVGTQAR
                     ILYQDCIGRVTVALKFNELVRKGKIGPVMIGRDHHDVSGTDSPFRETSNIKDGSNVTC
                     DMAVQCYAGNAARGMSLVALHNGGGTGIGKAINGGFGLVLDGSERIDEIIKSAIAWDT
                     MGGVARRNWARNEHAIETAIEYNRLHAGTDHITIPYLADDDLVTSAVDQLFH"
     gene            31911..33176
                     /locus_tag="VCR92_000354"
     CDS             31911..33176
                     /locus_tag="VCR92_000354"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HEP4267450.1"
                     /translation="MVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDG
                     LIVALGSGEPDAELVGPQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVS
                     YLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETE
                     KRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAE
                     FCDIFCEKNVFTADESRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLM
                     MITDDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPT
                     ANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNI
                     DYPFYFFATNLIHQVYKKGQLTVDRGRIL"
     gene            complement(33234..34766)
                     /gene="ahpF"
                     /locus_tag="VCR92_000355"
     CDS             complement(33234..34766)
                     /gene="ahpF"
                     /locus_tag="VCR92_000355"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEP4267451.1"
                     /translation="MALSPDIKEQLAQYLTLLEADLVLQVSLGDNEQSQKVKDFVEEI
                     AAMSERISIENITLDRQPSFKVAKKGHGSGVVFAGLPLGHELTSFILALLQVSGRAPK
                     VDQDVIDRIKAIDRPLHFETYVSLTCHNCPDVVQALNIMSVLNDKISHTMVEGGMFQD
                     EVKAKGIMSVPTVFLDGEEFTSGRATIEQLLEQIAGPLSEEAFADKGLYDVLVIGGGP
                     AGNSAAIYAARKGLKTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAEVEAHTKSY
                     DVDIIKAQLATSIEKKENIEVTLANGAVLQAKTAILALGAKWRNINVPGEDEFRNKGV
                     TYCPHCDGPLFEGKDVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTNNMTIIKNVATKDIVGEDHVTGLSYTERDSGEDKHLDLEGVFVQIGLVPNTAWLK
                     DSGVNLTDRGEIIVDKHGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            complement(34787..35347)
                     /gene="ahpC"
                     /locus_tag="VCR92_000356"
     CDS             complement(34787..35347)
                     /gene="ahpC"
                     /locus_tag="VCR92_000356"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEP4267452.1"
                     /translation="MSLIGKEIAEFSAQAYHDGKFITVTNEDVKGKWAVFCFYPADFS
                     FVCPTELGDLQEQYETLKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     LISQAFEVLGEDGLAQRGTFIVDPDGIIQMMEINADGIGRDASTLIDKIHAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            35754..35824
                     /locus_tag="VCR92_000357"
     tRNA            35754..35824
                     /locus_tag="VCR92_000357"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35786..35788,aa:Cys,seq:gca)
     gene            36343..36546
                     /locus_tag="VCR92_000358"
     CDS             36343..36546
                     /locus_tag="VCR92_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEP4267453.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQTNGFKTLEEG
                     QKVAFDVEEGQRGPQAVNITKLA"
     gene            36742..37203
                     /locus_tag="VCR92_000359"
     CDS             36742..37203
                     /locus_tag="VCR92_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEP4267454.1"
                     /translation="MPTKNTSDSIEEYIKELLAKSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGNLMATIEDCISEQVFTDSI
                     QLLFDEHLLTEREGNIILAVASDDVLGTDGSTIRARMLYRLLQRIDRKGSN"
     gene            37203..39647
                     /locus_tag="VCR92_000360"
     CDS             37203..39647
                     /locus_tag="VCR92_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEP4267455.1"
                     /translation="MIMYSTKMQDIFRQAQFQAARFDSHCLETWHVLLAMVAVDNSLA
                     NMILSEYDAQVAIEEYEAAAILAMGKTPKEQLSRVDFRPQSKTLTNLLAFAQAISQIT
                     RDQEVGSEHVLFAILLNPDIMASRLLEIAGYQIKDNGNGQPRLADLRKAIERHAGYSK
                     EMIKAIHELRKPKKTKTQGTFSDMMKPPSTAGELSDFTRDLTEMARQGLLESVIGRDQ
                     EVSRMIQVLSRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELKEMRVLELDMM
                     SVVAGTRFRGDFEERMNQIIDDIEADGQIILFVDELHTIMGSGSGIDSTLDAANILKP
                     ALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNTEDAYQILMGLKLSYET
                     YHNVSISNEAVKTAVKMAHRYLTSKNLPDSAIDLLDEASAAVQNMVKKSAPETLTPID
                     QALINGDMKKVSRLLAKEAKGQMRKPTPVTEDDILATLSKLSGIPLEKLTQADSKKYL
                     NLEKELHKRVIGQDAAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTELAKAL
                     AEVLFDDEAALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTQKVRNKPYSVLLF
                     DEVEKAHPDIFNVLLQVLDDGILTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFG
                     VKGIHQDHQAMEKRILEELRKTYRPEFINRIDEKVVFHSLTQDNMRDVVKIMVQPLIT
                     TLAEKGITLKIQPLALKHLSEVGYDEHMGARPLRRTLQTEIEDKLSELILSRELTSGH
                     TLKIGLSYGKLTFHIA"
     gene            39825..40115
                     /gene="groES"
                     /locus_tag="VCR92_000361"
     CDS             39825..40115
                     /gene="groES"
                     /locus_tag="VCR92_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEP4267456.1"
                     /translation="MLKPLGDRVVVRFDDEKEQTVGGFVLAGTHKESTRKATVLAVSE
                     TGVRTITGDSVLPSVSVGQEVLVENGHDLEVTVDDEKVSIIRESDIIAIVTK"
     gene            40151..41782
                     /gene="groL"
                     /locus_tag="VCR92_000362"
     CDS             40151..41782
                     /gene="groL"
                     /locus_tag="VCR92_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEP4267457.1"
                     /translation="MAKDIKFSADARAAMVRGVDMLADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVHEG
                     LKNVTAGANPIGIRRGIETATATAVEALKAIAQPVSGKEAIAQVAAVSSRSEKVGEYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKVSNIQDILPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATMTALGQAAKITVDKDSTVIVEGS
                     GSSEAIANRIALIKSQLETTTSDFDREKLQERLAKLAGGVAVIKVGAPTETALKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALITVIEKVAALELEGDDATGRNIVLRALEEPVRQ
                     IALNAGYEGSVVIDKLKNSPAGTGFNAATGEWVDMIKTGIIDPVKVTRSALQNAASVA
                     SLILTTEAVVANKPEPAAPAPAMPAGMDPGMMGGF"
     gene            42033..42299
                     /locus_tag="VCR92_000363"
     CDS             42033..42299
                     /locus_tag="VCR92_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4267458.1"
                     /translation="MNHFGEIFKTFRESKGLRLKDVAKAGISTSQLSRFEKGETDLTI
                     STFMLILDESNMSIDEFMYAVHDFHRDDLNELLSKSEGFRNNSR"
     gene            complement(43022..44521)
                     /locus_tag="VCR92_000364"
     CDS             complement(43022..44521)
                     /locus_tag="VCR92_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEP4267459.1"
                     /translation="MINKKISLGVLSILTAFSLQSVSYACTGFIIGKDLTKDGSLLYG
                     RTEDLEPHHNKNFIVRLAKDNPAGEKWKDPSNGFEYPLPEHSYRYSAIPDVTPNKGVY
                     DEAGFNEFGVSMSATVSASANDAIQKIDPYVKNGLAESSMASVILPSVKTAREGVALI
                     AKIVTEKGAAEGNIVTLADKDGIWYMEILSGHQYVAIKFPDDKYAVFPNTFYLGHVDF
                     NDKENTIASEDVEKVTKKAKSYTEVDGKFHIAKSYNPPLNDANRSRSFSGIKSLDPDS
                     KVTYKDSNYELLQSTDKTFSLEDAMKLQRNRFEGLDLKPLDQMALDGKGKPKSKKAVK
                     GYAYPISNPNVMEAHIFQLKKDIPAELGGGVMWLSIGSPRNAPYLPYLGNISRTYEAY
                     QEKSTQYNDKSWYWTVSHINDLVAAHPKPFGTKVIDEMKGLEKTWIAEQDKSTKEISD
                     LVVSDPKAAQEKADKISLDRAEKTFKRLKAIEAKLVEEKPQNKKGLNRS"
     gene            44768..46408
                     /locus_tag="VCR92_000365"
     CDS             44768..46408
                     /locus_tag="VCR92_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267460.1"
                     /translation="MTKPFHHKKLKQITIIAATSLFLFLIGGAFYYSKNHCINAYLKA
                     RSAQSGPVFENIKAYLVWDDTNEQITNDEAMYTKFRRYSQKELRQKKQDLKAASQDSA
                     VQVKSVGRRFWIFPDYRIAIKPMDLTIKTNVPQADVLLNQKKVAVSDSEQFSVKLDRL
                     PTAEYTASIRGKHNGRNIKVNKSYDGDNPVLDLSVSFRTFLVTSNAKQGDLYFDDNHI
                     GTLKDGQLQVEDYPVTENAQAYMKTTFPDGELRSQKYALADVEEGATLEILVTDLLEE
                     DKAGELLVSAFDQLMHYLSTGQDSSNLRSVFEAGSSNAFYRGLKESIKAKFQTDTRKA
                     SRLNIPSILLTTMTQVGKTTYVLDFTATYEFLYDNSTDPEQHTSGHINQDLTGKVTVK
                     KVGQHYLISQSGSKNITVVKEDNQLKAPSVFPESILGTWTGQANGLSIHMSLASDGTI
                     TTKVEDRKGNRSKETRTAKISKVEDKGNGFYLYTPDPGSDISALAPEGGLGGANVKYA
                     YGFKISGKTASPVVWQAALTHEFDYTKPLSGVTLQKQP"
     gene            complement(46497..47498)
                     /locus_tag="VCR92_000366"
     CDS             complement(46497..47498)
                     /locus_tag="VCR92_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEP4267461.1"
                     /translation="MTSVKVLKLSLLLLPPKWLSTLLKNTITGSMKTTNKPSKGFTVT
                     LKNPFEELTVKALLEEQLLIPRKIRHFLRTKKHVLINGHPVNWQSCVKYGDQVKLFFD
                     HEDYPEKIIVMGQAEKVTCLYEDEHIIIVNKPEGMKTHGNDPTELALLNHVSAYTGQT
                     CYVVHRLDKETSGAILFAKTPFILPILNRLLEKRDIHREYLALVHGSLDSPRVTYHHP
                     IGRHRHDRRKRVVDPINGKKAITEVTLVKNFHKTASLLNCQLQTGRTHQIRVHLAHQG
                     HVLFGDPLYSNGKKDCARLMLHAYQLRLKHPLTQEDICVQAKSATFDAVLNAQKARK"
     gene            48075..48455
                     /locus_tag="VCR92_000367"
     CDS             48075..48455
                     /locus_tag="VCR92_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEP4267462.1"
                     /translation="MKTIRRYDVNEDRGHTGLVEAGDFYYLNYCVGNVGQDIESQING
                     AFDEMERRLALVGLTLDAVVQMDCLFRDVWNIPVMEKMIKERFNGRYPARKSIQTEFA
                     HHGGPQGLLFQVDGVAYSKHISMT"
     gene            48494..50830
                     /locus_tag="VCR92_000368"
     CDS             48494..50830
                     /locus_tag="VCR92_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEP4267463.1"
                     /translation="MRFLELLQKKFFPKAYQEKQFLMHQKTRLTPQHNQKQYSPNANH
                     LDSSATKNSEQDPAIALQRSRAYEGSPKSRPAWLQKLEAVLPSPQHPIRRFWRRYHIG
                     KLLMILIGTLVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDHKGEYAGSLSGQKGSY
                     VELNAISDDLENAVIATEDRTFYSNSGINLKRFLLAVVTAGRFGGGSTITQQLAKNAY
                     LSQDQTIKRKAREFFLALELTKKYSKKDILTMYLNNSYFGNGVWGVEDASQKYFGTTA
                     ANLTLDEAATLAGMLKGPEIYNPYHSLKNATHRRDTVLGAMVDAKKITQTKAQQARAV
                     GLKNRLADTYVGKTDDYKYPSYFDAVISEAIATYGLSEKDIVNNGYKVYTELDQNYQT
                     GMQTTFNNDELFPVSAYDGSSAQAASVALDPKTGGVRGLIGRVNSSENPTFRSFNYAT
                     QAKRSPASTIKPLVVYAPAVASGWSIEKELPNTVQDFDGYQPHNYGNYESEDVPMYQA
                     LANSYNIPAVSTLNDIGIDKAFTYGKTFGLDMSSAKKELGVALGGSVTTNPLEMAQAY
                     AAFANNGVIHPAHLINRIENARGEVLKTFTDKAKRVVSQSVADKMTAMMLGTFSNGTA
                     VNANVYGYTLAGKTGTTETNFNPDLAGDQWVIGYTPDVVISQWVGFNQTDENHYLTDS
                     SAGTASAIFSTQASYILPYTKGSQFHVDNAYAQNGISAVYGVNETGNQSGVDTQSIID
                     GLRKSAQEASQSLSKAVDQSGLRDKAQSIWKEIVDYFR"
     gene            50879..51031
                     /gene="rpmG"
                     /locus_tag="VCR92_000369"
     CDS             50879..51031
                     /gene="rpmG"
                     /locus_tag="VCR92_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEP4267464.1"
                     /translation="MAQKKASLACVECGSRNYSIGVSSTPKPTRLEVNKFCKYCKTYT
                     LHKETR"
     gene            51045..51221
                     /gene="secE"
                     /locus_tag="VCR92_000370"
     CDS             51045..51221
                     /gene="secE"
                     /locus_tag="VCR92_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEP4267465.1"
                     /translation="MGFISGTFKVLKDTTWPNRKQRWKDFISVLEYTAFFTVIIYIFD
                     QLLAKSVLALINLF"
     gene            complement(51458..52231)
                     /locus_tag="VCR92_000371"
     CDS             complement(51458..52231)
                     /locus_tag="VCR92_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEP4267466.1"
                     /translation="MTDRGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQQ
                     KAPEQMLTSDGLNTKIVGEEKTVDEVIEEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAAGLHTAIETTAFAKHEQFVTLIDYVDFIYTDLKHYNQLRHQKVTGVRND
                     LIIKNIHYAFQAGKEIVLRIPVIPQFNDSLDDAKAFSELFNQLEIDQVQLLPFHQFGE
                     NKYKLLGREYEMAEVKAYHPEDLADYQAVFLNHNIHCYF"
     gene            52357..53103
                     /locus_tag="VCR92_000372"
     CDS             52357..53103
                     /locus_tag="VCR92_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEP4267467.1"
                     /translation="MNRLERIIQLVSQKKKIDVNSLSEQLEVSKVTIRKDLDKLESKG
                     LLRREHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKRNIKIITNSCFIANYIRQYSSCQIILLGGYYQPNSEVTVGPLLKEMISLFHV
                     NRVFVGTDGFNKDLGFMGKDMMRSEGVRYMADAAEEVVILTDSSKFSKTSLVHQLSLA
                     DVNRVITDQALDKQTQELLSSGGLVLDFVS"
     gene            53119..54099
                     /locus_tag="VCR92_000373"
     CDS             53119..54099
                     /locus_tag="VCR92_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEP4267468.1"
                     /translation="MKEERRRLLAKVAYLHYVQGKSQTLISKEMNIYRTTVCRMLAKA
                     KEEGIVRIEIADYDADLFALEEYVRKQYGLEKLDLVPNQVEDTPMDTLTNVAKTAAEV
                     FRHVVKDGDKIGLSWGATLSCLMDELNPKAMKDVFIYPLAGGPSHINAKYHVNTLVYR
                     LARIFHGNSAFMNAMVIQEDKHLAKGILQSKYFNDILTSWDQLDLALVGIGGEPNSLE
                     QSQWRDLLTSSDHDQLKYEKAVGEVCCRFFDQAGQPVYTGLQDRTIGISLEQLRRVPK
                     TMAVATGKHKAKAILAALKAGFINYLVTDKETMLAVLALDEDIDLNNVLL"
     gene            54387..54707
                     /locus_tag="VCR92_000374"
     CDS             54387..54707
                     /locus_tag="VCR92_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEP4267469.1"
                     /translation="MQVIVPDQIIMGLILNAGDAKQHIYQALKCAKEDDYATSEKEMA
                     LADDALLEAHNLQTQFLAQEASGNKSEITALFVHSQDHLMTTITEINLIKEIIDLRKE
                     LATK"
     gene            54735..55043
                     /locus_tag="VCR92_000375"
     CDS             54735..55043
                     /locus_tag="VCR92_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEP4267470.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIDCQIEAYAQGKLAD
                     YAPLLDVALLGPQVAYTLDKSEAICKDNDIPIAVIPMADYGMLDGNKVLDLALSLVKE
                     "
     gene            55053..56357
                     /locus_tag="VCR92_000376"
     CDS             55053..56357
                     /locus_tag="VCR92_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEP4267471.1"
                     /translation="MAKMNMQNIIKPIMTFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVFGADWTEPFMQVYHGTFAIMGLISCFAIGYSYAKNSDVEPLP
                     SGVLSLSAFFILLRSSYVPAEGEAIGDAISKVWFGGQGIIGAIVIGLTVGAVYTTFIR
                     RHIVIKMPDQVPQAIAKQFEAMIPAFVIFTLSMLVYIIAKSVTGGGTFIEMIYDVIQV
                     PLQGLTGSLYGALGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALMAAGELS
                     LDKGAHIVTQQFLDSFLILSGSGITFGLVVAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVLAALTVYGAIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGAIVQILILIMSTLVYFPFFKIQDNMAYQNEQASEES"
     gene            56568..58985
                     /locus_tag="VCR92_000377"
     CDS             56568..58985
                     /locus_tag="VCR92_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEP4267472.1"
                     /translation="MIETKSPYFGHLTDRMAHYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPANLKRAYMLQTILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRDIAPFWENNNLRARCGVLLPEEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEHGLKGFEERARAAKAALDLTIPENIDKYHFYDSVFIVIDAV
                     KTYAKRYAKLARELAKTAKPERQAELLDIARICDKVPYEPAKTFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYVKADLEAGRETEDTIVERLTNLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNT
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDMTSYEELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTPEELWHALESDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKLKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            58998..59666
                     /locus_tag="VCR92_000378"
     CDS             58998..59666
                     /locus_tag="VCR92_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEP4267473.1"
                     /translation="MEYMLDTLDLEAIKKWHHILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVIAQDYEGILKDAAEIRRQCGDSVYVKVPVTTEGLAAIKTLK
                     AEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAINRENA
                     DSKILAASFKNVAQVNKSFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWEAIHH
                     RKSI"
     gene            59723..60811
                     /locus_tag="VCR92_000379"
     CDS             59723..60811
                     /locus_tag="VCR92_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEP4267474.1"
                     /translation="MKVFASPSRYIQGKNALFTNAKTLKQLGNSPILLCDDVVYGIVG
                     ERFESYLIDNGMTPVHVAFNGEASDNEISRVVAIAKENGNDVIIGLGGGKTIDSAKAI
                     ADLLAVPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYSKNPDLVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGVAIAKACEQTLFADGLKAMA
                     SCDRQVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGAIHHLTHGEKVA
                     YGTLTQLFLENRSREEIDRYIDFYQAIGMPTTLKEMHLDTATQEDFLKIGRQATMAGE
                     TIHQMPFVISPEDVAAALVAVDAYVTSR"
     gene            complement(60893..61402)
                     /locus_tag="VCR92_000380"
     CDS             complement(60893..61402)
                     /locus_tag="VCR92_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HEP4267475.1"
                     /translation="MSTDHHLREVSYQLLAERGVSLEAIAELVLFLQNDYIPNLTMAE
                     CLESVEAVLAKREVQNAIITGVELDKLAEANQLSEPLLSILKTDQGLYGIDEILALSI
                     VNLYGSIGFTNYGYLDKTKPGIVDKLNHKDGNSCHTFLDDIVSAIAAAAASRIAHNDP
                     AKSAITNQQ"
     gene            61766..62581
                     /gene="sdaB"
                     /locus_tag="VCR92_000381"
     CDS             61766..62581
                     /gene="sdaB"
                     /locus_tag="VCR92_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase B"
                     /protein_id="HEP4267476.1"
                     /translation="MNLLGSRRVFSKKCRLVKFSMVALVSATMAVTTVTLENTALARQ
                     TQVSNDVVLNDGASKYLNEALAWTFNDSPNYYKTLGTSQITPALFPKAGDILYSKLDE
                     LGRTRTARGTLTYANVEGSYGVRQSFGKNQNPAGWTGNPNHVKYKIEWLNGLSYVGDF
                     WNRSHLIADSLGGDALRVNAVTGTRTQNVGGRDQKGGMRYTEQRAQEWLEANRDGYLY
                     YEAAPIYNADELIPRAVVVSMQSSDNTINEKVLVYNTANGYTINYHNGTPTQK"
     gene            complement(62822..63664)
                     /locus_tag="VCR92_000382"
     CDS             complement(62822..63664)
                     /locus_tag="VCR92_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEP4267477.1"
                     /translation="MEIGETVEFIRHSKNISIKQVCGDYLTRQTYYRFIKNNLDISSK
                     KLLYILDNLNVNVDEFLFISNNFKQYKEFIDMDTAKHYFECRNIEGLNHILDSYKDSK
                     STKEKNLFALVKVLLATLTEEDCLTERTYLSNYLINIETWSHYETVLFNNCMFIFESC
                     FIEMVFSKVILNLDKYNTLRYYGNESIRMFVNMLILFIQRQEYDKASEILAKIEDYQL
                     NDDCLYERCCVSFFDGIIGLINGKEGAEQKCVQILEIFQLLNCKTIHHMFQTYLEAIK
                     HKLS"
     gene            64605..65801
                     /gene="speB"
                     /locus_tag="VCR92_000383"
     CDS             64605..65801
                     /gene="speB"
                     /locus_tag="VCR92_000383"
                     /EC_number="3.4.22.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine proteinase exotoxin SpeB"
                     /protein_id="HEP4267478.1"
                     /translation="MNKKKLGIRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAIT
                     FIQKSAAIKAGARSAEDIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILG
                     YSTSGSFDANGKENIASFMESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHY
                     NQGNPYNLLTPVIEKVKPGEQSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTL
                     SSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDY
                     GPSSGSAGSSRVQRALKENFGYNQSVHQINRSDFSKQDWESQIDKELSQNQPVYYQGV
                     GKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALNPSALGTGGGAGGFNGYQSA
                     VVGIKP"
     gene            65803..66108
                     /locus_tag="VCR92_000384"
     CDS             65803..66108
                     /locus_tag="VCR92_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spi family protease inhibitor"
                     /protein_id="HEP4267479.1"
                     /translation="MEMHFVRTEPEARRIAETFCAENTQTKTPMRVQQLSYPSDTDHS
                     GGELYIYALSPAGFIIVSGDTRAHTILGYSFDNNLDLNHDNVRSMIEAYQTQINSLD"
     gene            66586..67515
                     /gene="prsA"
                     /locus_tag="VCR92_000385"
     CDS             66586..67515
                     /gene="prsA"
                     /locus_tag="VCR92_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEP4267480.1"
                     /translation="MKQMNKLITGVVTLATVVTLSACQSSHNNTKLVSMKGDTITVSD
                     FYNETKNTELAQKAMLSLVISRVFETQYANKVSDKEVEKAYKQTADQYGTSFKTVLAQ
                     SGLTPETYKKQIRLTKLVEYAVKEQAKNETISKKDYRQAYDAYTPTMTAEIMQFEKEE
                     DAKAALEAVKAEGADFAAIAKEKTIAADKKTTYTFDSGETTLPAEVVRAASGLKEGNR
                     SEIITALDPATSKRTYHIIKVTKKATKKADWKAYQKRLKDIIVTGKLKDPDFQNKVIA
                     KALDKANVKIKDKAFANILAQFAKPNQKQPAQK"
     gene            complement(67791..68027)
                     /locus_tag="VCR92_000386"
     CDS             complement(67791..68027)
                     /locus_tag="VCR92_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267481.1"
                     /translation="MTHRFFLTPLSTLWRRLRPKRYSKKVLADEPTSYQPPAAHGPCD
                     DIHQLLEDKSLSDDYLIATSAMRHLWYWGYSQIG"
     gene            68451..71531
                     /locus_tag="VCR92_000387"
     CDS             68451..71531
                     /locus_tag="VCR92_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEP4267482.1"
                     /translation="MTNCKYKLRKLSVGLVSVGTMLIAPTVLGQEVSASSSTESSTTT
                     ANTGTGTASGMTATTPSATTDTGEAAGSGARSEANGASSVVSSEESQSSGTTPASPQA
                     QTAPAATSTSSASSSNEKTPKTATTTTSSTPVASTSNNSNKVTSTEAETQTMDVERYT
                     VDKENSKLNIKDGKTPKTRSSVNKDTKLIRNRDDKQRDIVDVTRTVKTNEDGTIDVTV
                     TVKPKQIDEGADVMALLDVSQKMTKENFDKAKEQIKKMVTTLTGEPTDGKENHNRRNS
                     VRLMTFYRKVNEPIELTAENVDKTLDEVWKKAKEDWDWGVDLQGAIHKAREIFNKEKE
                     KKSGKRQHIVLFSQGESTFSYDIKNKSDITKTKITEKVTTSSPLFPWLPIFNHTNRKA
                     EIIGDLEKVLDMAEKVGISLPSSLKSAVKALGLTNSAIGSILGKGLTEYLGLTEYSSD
                     NLDGGGFDYSKRVGEGYYYHSFSDRKYENTMPLEEAIRTALASNFPKLTDNWFFDILN
                     SFVNKDTVEKAKLDVIMKVLNSIFYKREYRYYNHNLSAIAEAKMAQQEGITFYSVDVT
                     DLNSASKRVRRQAAVRKGTKEEENKKNEEERNTKFDTYLKKMSEGNNFLSNVEERDKF
                     KDTLTELTIKDEFTDKVTVEKDSWSKSITDGLKNSNNNNVKHQQANTSTWSFFSSSKE
                     SLTWIISKEQLKEAFEKNGSLTFKYKLRVNKDKLLDKDKKRTKRDTPTENKTSVTADI
                     ISNTVDYKINNQEVKGNKLDAVKLTYTKETVPVPDVEGEVVPIPEKPLVEPMTPLYPA
                     IPNYPTPQLPKDEDLEISGGHGPIVDIVEDTGTGVEGGAQNGVVSTQENKDPIVDITE
                     DTQPGMSGSNDATVVEEDTAPKRPDVLVGGQSDPIDITEDTQPSVSGSNDATVVEEDT
                     VPKRPDILVGGQSDPIDITEDTQPGMSGSNDATVIEEDTKPKRFFHFDNEPQAPEKPK
                     EQPSLSLPQAPVYKAAHHLPASGDKREASFTIVALTIIGAAGLLSKKRRDTEEN"
     gene            71711..73648
                     /locus_tag="VCR92_000388"
     CDS             71711..73648
                     /locus_tag="VCR92_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEP4267483.1"
                     /translation="MTKKFIKSAVILGLASITISMTQPVEAISNSLEYQAQYERVKEE
                     LDALKEKGPKLGERSLYFRLVNKFLSWFGQVWDPLAIKETDYLLDLIGQVNYLVSNTE
                     FQAPEYKDAKNKLDLAVAGYDLYLAREKKRGDAPDYQVTQLTLEQLKTIKKKIREALE
                     TFAQEVKTIQQKNPDLFPHAYVLNAKSKDITDKAQPFLVNSYYDVFYKQFLFTNTNDG
                     YNYNKEADNLTSYQNLIKELLGLKAEIDQLTKGKTGDDRLEMLMWQSKFTLSDSRKKS
                     HLSAYYTQGEYVDKVVLSEEAPNLRTAKEKVKTLKGILHDYYVETNKPEKAKKYHVED
                     ETLPSQPEAPATPEAPAPAPVPVPGQKPAEDERSPQATEPANPSKEDSSTDASQGSHD
                     SENPATDSPSQPQAPDQGNHQSQVPNAKPQTDKTDTPNAPAIPQDTPKAPEAGGQSGP
                     AGNTEEKAPDSGPKESDQSSSKESPSVGEDTTPNQPDVLVGGQSEPIDITEDTITDAP
                     PTVSGHNASTQPQSVVEDTAPQRPDVLVGGQSEPIDITQDTQPGMSGSNDATVINEDT
                     KPKRVFHFDNKEPQASEKAAEQKLAPHDSHTTPQASDDTAAPHLPASGDKPEKVFALA
                     ALTMVAAAGLLSKKRRNTDKN"
     gene            73790..74086
                     /locus_tag="VCR92_000389"
     CDS             73790..74086
                     /locus_tag="VCR92_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4298 domain-containing protein"
                     /protein_id="HEP4267484.1"
                     /translation="MTKQDQLIVEKMEQTYEAFSPKLANLIEALDAFKEHYEEYATLR
                     NFYSSDEWFRLANQPWDDIPCGVLSEDLLFDMIGDHNQLLADVLDLAPIMYKHM"
     gene            74235..74519
                     /locus_tag="VCR92_000390"
     CDS             74235..74519
                     /locus_tag="VCR92_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEP4267485.1"
                     /translation="MKFKKVLVIPALALAATCFLTACGTKKDSKKEEVKEIKMSDIKD
                     DAVSKKTKVVDGEEVTEYTTKDGNVIQIPAGNEEGMESKDAGGSGAPAKN"
     gene            74953..76221
                     /locus_tag="VCR92_000391"
     CDS             74953..76221
                     /locus_tag="VCR92_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEP4267486.1"
                     /translation="MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEIVSSVN
                     KVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKDVFVKKGDVVKVGQP
                     LFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAP
                     DESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKANATATTEKGKLEYDTVKSD
                     TAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIGQKVEVID
                     RKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLI
                     GSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVE
                     VTSGLTMQDKIAQPLPGMKDGMEVGSIVKP"
     gene            76208..76882
                     /locus_tag="VCR92_000392"
     CDS             76208..76882
                     /locus_tag="VCR92_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4267487.1"
                     /translation="MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGK
                     STLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQ
                     NVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNP
                     SFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNI
                     EHSDIE"
     gene            76895..78112
                     /locus_tag="VCR92_000393"
     CDS             76895..78112
                     /locus_tag="VCR92_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4267488.1"
                     /translation="MEDIIAALSSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTE
                     NTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVK
                     NALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYL
                     EKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNI
                     NGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLN
                     KSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEA
                     VILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIK
                     ASKLDPIEALRFE"
     gene            78206..78859
                     /locus_tag="VCR92_000394"
     CDS             78206..78859
                     /locus_tag="VCR92_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP4267489.1"
                     /translation="MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTT
                     SYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKP
                     FSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLA
                     KRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE"
     gene            78856..80244
                     /locus_tag="VCR92_000395"
     CDS             78856..80244
                     /locus_tag="VCR92_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEP4267490.1"
                     /translation="MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKR
                     EFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDS
                     QNVNIVTTFDNSYSNVKVMSQKVTLRDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLM
                     FSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRL
                     YASLSTSIKSLQKEYEKASDSEREKSEFLRMTSHELKTPITSVIGMIDGMLYNVGDFA
                     DRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSE
                     LKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKSGGQVMIQLKDNQLVIKNEA
                     ETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLAYRFVVLDQRWM
                     VFTIDFPSHHDD"
     gene            80346..81971
                     /locus_tag="VCR92_000396"
     CDS             80346..81971
                     /locus_tag="VCR92_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEP4267491.1"
                     /translation="MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNNTSSTDQPTTAD
                     TDTDDESETAKKDKKSKETASQHDTQKDHKSSHTHLTPPSNDTKQTDQASSEATDKPN
                     KDKNDTKQPDSSDQSTPSPKDQSSQKESQNKDGRPTPSPDQQKDQTPDKTPEKSADKT
                     PEKGPEKATDKTPEPNRDAPKPIQPPLAAAPVFAPWRESDKDLSKLKPSSRSSAAYVR
                     HWTGDSAYTHNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVRA
                     IVAIAMAESSLGTQGVAKEKGANMFGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIANK
                     NQTFERQDLKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMIKLDQWIDDHGSTPE
                     IPEHLKITSGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVDR
                     YMGNGGDWQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILISE
                     SNVMGLGTISYRTFTAEQARLLTYVVGDKLPRP"
     gene            82049..82300
                     /locus_tag="VCR92_000397"
     CDS             82049..82300
                     /locus_tag="VCR92_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267492.1"
                     /translation="MIKKVTTPSQKIKKRVRNGYLLKLGTACLLLSILSYGIGLLGQP
                     SMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD"
BASE COUNT        25679 a        15985 c        17471 g        23450 t
ORIGIN      
        1 aaagattctg ttatacttgt tttataatat tctttgacga taatatcatt tttcaactta
       61 ctttgtttat gcactgtcac tttgctatgt gcaatacaaa gtcatgttat ttatctcata
      121 ctaaaaaaat aatggataat agctatgtta gactagtgat atgaagaaat attgctttta
      181 ttgaatcgtt agagaatatg atatttcaag gagaaaaata gtgatcgagt taaacgatga
      241 attcatccga aaagagacga tagaactggc caacgatggc ccacgagtac acaccactca
      301 atatgaaact aaagtacctc ggcttcataa atgctatctg cttttcttta gcattattat
      361 cagttcttta acaattgcag tacctttttt aacagatgca gccaatggtc ttcagtccca
      421 aaacttatat ataggaatga tgttaacgaa ggggcaactt ccctatagtg atgcttttac
      481 aacaggaggg ctcttttact ttgttatcat tgcattaagt tattatttgg gatcgacact
      541 ttggctagtc tttgttcagg tgttttgttt ttacttatct ggtttatatc tttataaact
      601 cattaattat atgacatgct ttcaaaaagt ggctttaact ttttcaatta gctactattt
      661 gttgtctgtt agtcttggtt ttggaggatt gtatcctact caactggcta tgccatttat
      721 attaatatcg gcttggtttt taactaagta ttttgcctgt ttagtgaaag atgaggcatt
      781 tattcttttt ggctttgtag gtgctcttgc aatgctaatt gacccgagta cccttatctt
      841 ttggtctttt gcttgtgtga cagttttttc ttataatata agccaaaagc atcttgcaag
      901 aggtttttat caactgctag cttcgatttt tgggatgatt ttagtttttt acacagcagg
      961 atatttcatt ttgaacttac aagtgctaaa tccttattta tcacaaacga tgatttatcc
     1021 ttttactttt tttaaatcag gaaacttatc gttgcttttt ggactggcta ttcagttgtt
     1081 cttcgctttg gggcttggtc ttttgacagg aatggggaat gtcattaggc gatttaaaaa
     1141 caattctgat agggtcgtca agtggctatt tgtcatggtc attctagaat ctatacttgt
     1201 ggctatattt tcacaagact atcgccccta tcatctttta cctcttttac cttttggatt
     1261 aattttgact gctattcctg ttggctatca gtatggtata ggattaggtc agagtagtca
     1321 tcgcagacgt catggtaaaa atggtgttgg tcgagtaatg atgatttatc ttaagagaca
     1381 cttttatttg ccaattttaa ttgtagggac aatactaatc tgttctactt attgtttcat
     1441 tagtagtatt cctcttaatc aggagcgtga tcatattgct agttatttag aacagaaact
     1501 aaataaaact caatctattt atgtttggga tgatacttct aaaatttatt tggacagtaa
     1561 agctaaatct gtttctcaat ttagttctcc tgacatcaat acgcaaaaag cgagtcatcg
     1621 aaaaatatta gaagatgaac tattagaaaa taaggctgct tatatcgttg ttaatcgcta
     1681 taaaaacctg cctaaaatca ttcaaaaagt attatctact aattacaaag tagataaaca
     1741 gataacgaca aaaagtttta ttgtttatca gaaaaagtaa tctaatatca atatattgtg
     1801 ttcgagcaaa aaacttgaca caatatattg atttttttag ttgtcgtgat ataatagttc
     1861 cgtaaggaga tttgatatgg taagtttaga agaagacaag gtgactgttc aacctgatat
     1921 taaagtgatt aaacgagatg gtcgccttgt taattttgat agtacaaaaa tctatagtgc
     1981 tttattaaaa gcaagcatga aagtaactcg gatgtcgcca cttgttgagg ctaaattaga
     2041 ggctatttct gatcgcatta tagcagaaat tattgagcgt tttccaacta atatcaaaat
     2101 ttatgaaatc caaaatattg tagagcataa gcttcttgca gctaatgaat atgctattgc
     2161 aaaagaatac attaattatc gtactcagcg tgactttgca cgttcacaag caacagatat
     2221 caatttttct attgataaat taattaataa agatcaaaca gttgttaatg aaaatgctaa
     2281 caaagatagc gatgttttta atactcaacg agatttaact gctggaatcg tagggaaatc
     2341 gattggttta aaaatgttac cttcgcatgt tgctaatgct catcaaaaag gagatatcca
     2401 ttaccatgat ttggattaca gtccttatac accgatgacg aactgctgtt taattgactt
     2461 taagggcatg ttagccaatg gctttaaaat tggtaatgct gaagtggaaa gtcccaagtc
     2521 tattcaaact gcaacagctc agatctcaca gattattgcg aatgtagcat caagtcagta
     2581 cggcggatgc acagctgatc gcattgacga gtttttagcc ccatatgcgg agcttaactt
     2641 taaaaaacat atggctgatg ctaagaaatg gatcgttgag actaagagag aaagctatgc
     2701 ttttgaaaag actcaaaaag atatttatga tgcgatgcag tctttggagt atgaaattaa
     2761 tacgctcttt acgtctaatg gtcaaacacc atttacttct ttaggatttg gtttggggac
     2821 gtcttggttt gaacgtgaga ttcaaaaagc tattttgacc attcggatta atggtcttgg
     2881 tagtgaacat cgcacggcta ttttccctaa attaattttc acggttaaac gtggcttgaa
     2941 tttagaacca gattcaccaa actatgatat taagactttg gctttagaat gtgcgactaa
     3001 gcggatgtac ccggatatgt tatcttatga taaaattatt gatttgacag gatctttcaa
     3061 atctccaatg ggatgccgct ctttccttca aggctggaaa gatgaaaatg ggcaagatgt
     3121 gacctcaggc cgtatgaatc ttggggttgt caccctcaat ttacctcgca ttgccatgga
     3181 atcaaatggc gatatggata agttttggga gctgtttaat gagaggatgc taattagtaa
     3241 ggatgcttta atttatcgtg tcgaacgtgt cacagaagca aaaccagcaa atgcccctat
     3301 tctttatcaa tatggtgctt ttggaaagcg tttggagaag acagggaatg taaatgatct
     3361 ctttaagaat cgtcgtgcaa cagtctctct tggctatatt ggtctttatg aagtggcgtc
     3421 tgttttttat ggtggtcaat gggaaggtaa tccagatgct aaagctttta ccttgtcaat
     3481 tatcaaggca atgaaacagg cctgtgagga ttggtcagat gaatatggtt atcatttctc
     3541 tgtttattcg actccatcag aaagtttgac agatcgcttt tgtcgtttag atacggaaaa
     3601 atttggcatt gtgacagata ttacggataa agaatactat acaaattctt ttcactatga
     3661 tgtgcgtaag agtccgacac cttttgaaaa attagatttt gaaaaagatt atccagaagc
     3721 aggtgcttca ggtggtttta tccactactg tgagtatcct gttttgcaac aaaatccaaa
     3781 ggccttggaa gcggtttggg actatgctta tgatcgtgtg gggtatttgg gaaccaatac
     3841 gcctattgat aaatgctata attgccaatt tgaaggcgat tttaccccaa cagaacgtgg
     3901 ttttacttgc ccaaactgtg gcaataatga ccctaaaaca gttgatgtgg tcaaacgtac
     3961 atgtggttac ttggggaatc ctcaggcccg cccaatggtt aacggtcgcc ataaggaaat
     4021 ctctgcgcgt gtaaaacata tgaatggttc tactataaaa tacccaggcc tgtaaactca
     4081 agctggggga gagccctttt gatggaaata tgatatgctt aaaaggttgc ttcatgcaag
     4141 caatctttta ttgtttaatg gtttcttagc aattgtgaga taagaataac taatccaaaa
     4201 cgactaatta gctgttagca atcggactat aagaagaaag agataaggaa gaaataatgg
     4261 gaaaatatca attagactat aaaggaatgc agcaggtaga acgctttcat gagaagcatt
     4321 ctaaaaaaaa gacggataaa aaatcccgcg ttcaagaact taaggctcgg tttttagaga
     4381 agtcaaaaaa acaggataac taaagtatcc aataaagaaa gaaggttgag tatgcttaat
     4441 attgggattg tgggactagg tgccatttca caaaaagcct atttaccata tatgagacag
     4501 ctgagtgaca ttacttggca tctatcaacg cggaatgcag cagtacgtca gcaggtcggt
     4561 cagttatttg gtcacgctat tctttacagt gatgtcaagg agttgtcaaa ggcaagttta
     4621 gatggcgtct ttattcatgc ggccacatcg gcccacgcag agttggctag tttattttta
     4681 aatcagggga tcccagtctt tatggataaa cctatagctg acaattacct gatgacaaag
     4741 aacctctatg acttagccaa agaaaatcag acttttctga tggcaggatt taacagacgt
     4801 tttacacctc gtgtcaagaa gttgtcaagt ttgtcaacta agcgtaaagt ggctgttgaa
     4861 aaaaatgact tgaaccggcc aggagatatg acttttaagc tctttgattt ctttattcat
     4921 cctttagata cagccttatt cttgtcagaa gggaccttac taaaagggca ttttcaatat
     4981 catctggaag caggcttact gagtcaagtt atggtaacct tgatgaccga aagcatgacg
     5041 actacagctt ctatgaattt acaatcaggg agtcgccgtg aggtaatgga agttcaacgg
     5101 gctgaagaaa cttatcattt agagaactta gacgagttat ctatttataa aggtactgaa
     5161 aaaagggtgc ttggctttgc ttcttgggac actaccttgc acaaaagagg ttttgaaaca
     5221 atgatcgatg cctttttaga agctattagc acaggcgtca atcctgtcag tcctgagtct
     5281 agtcttttaa gccactggat ttgtcaacag attgctgact ctcagctttc ttatggagag
     5341 ttaacggtag agttgcctaa ggattaggaa ttgatatgga aataagacga ccgactttaa
     5401 aagataaaga cgctgtattg tcaatgatta acgaattttt agagcagaaa agtgctacag
     5461 atgggttatg gcattttaac gtcaatgact ttaactatga aacatggttg gaagattcct
     5521 tgcgacagga aatgggtttg tccagtcaag gagtgcctgc tattcaatac gtcgcatttg
     5581 atgagagaag tcaggctatc gggttcttaa atcttcgttt acggttaaat gagagattac
     5641 ttgaaaaagg tgggcatatt ggttactctg tccgtcccag ccagcgtggg aaaggttatg
     5701 ccaaggagat gcttaaacaa gctgtcagct atgcgatttc caagaatatc acgacaattt
     5761 tggtaacttg tgatgagact aatgttgcaa gccgagcagt tattgtggct aacggtggtg
     5821 tcttggaaga tagtcgaggt ggaacggaac gttattggat tgaagaacaa agaggcgata
     5881 agtgatggca gaaaagtgtt ggaataatcc taagccaaag gaatggcagg cagaggagtt
     5941 aagtcaaggc cggattattg actataaggc ttttaacttt gttgatggtg aaggagttcg
     6001 taattccctt tatgtgtctg gttgtttatt ccattgcaag gggtgttata atgctgcgac
     6061 ttggtctttt aaggcgggaa tgccttatac gcaagaactt gaagagcaga taatgacgga
     6121 tttggcacag ccttatgttc agggactgac acttttaggt ggagaaccct ttttgaatac
     6181 gggtatctta attcctctga ttaagcgtat tcggcgtgaa ttgccagaaa aagatatttg
     6241 gtcttggacg ggttatactt gggaagaaat gatgcttgaa acaccagaca aactggaaat
     6301 gctgtcctta attgatattc tggtagatgg tcgttttgat atcacaaaaa agaacctcat
     6361 gttgcaattt agaggctctt ctaaccagcg aattatcgat gttcaaaagt ctttggctgc
     6421 taaagaagtg attatctggg ataagttaaa cgatggggac caaacctttg aacaaattag
     6481 tcgggaggat ttgctttaag aagctgactt atccacatga tttttttgaa aaggtcatgt
     6541 gaaaacaggt cctttaaggg tgaattgggg agaaagtaat tgttatttcc tggttttccc
     6601 cacattatcc tcatagttat ccacaggttg tgtataagtt gtagaattgt gaataaagac
     6661 taaaaaagag gcctaggcct cttttttgat atagacaaat tcatgatctg ttgataggtc
     6721 tggatggtag taaaaaccag caaagacaag gcttttaagg ctgtcaacag tttggcaatt
     6781 attttccata caggcagtga gaaatgcacc tcgtgccttt tttgaaatgg tggaatgggt
     6841 tttgaattgg ccctcttttt ctgccataaa cttgggactt atccacaatt gtttacagtc
     6901 tttggaaaag acatcgtcaa attcactgga taaaagggaa atcacttggg gatgctcttt
     6961 ggcaaactga ttataacagg gccgccagta agacttgagg ctttgtcctt caatttttat
     7021 tctggtgtga aaatcatggc ggtgctctgc gataggatga ttagcgggaa tgataccgta
     7081 aaaggatgag gtgatgtaaa cttgctgggt gaggtaagcc tgttcttggg tagtgagctt
     7141 atcgcgcttg atatggcggt acataaggcc attgaacagt tggtaggcag ggtaagccaa
     7201 gttttgttga gaggccatgt cttgccagcg ttgctgttct tttttagctg cctcttcttt
     7261 gatacgatag gatttggcca agtcctccgt ggtcatagct gccatgattt ttaaaatggc
     7321 ttggctgtct tgtggaagga ggtgtgggtg agattcctta gggatcatca tttcttttgc
     7381 ggttggaatt aaaaaggtta gcatagtgtt attgtagtaa agttacttgc tttctgtcaa
     7441 gaaaactagt cttgtccaag gatgacgttc acacagatac cttcctcgtc ttctgtcgtg
     7501 aaagaagaag aatcttcttg taaaatagct aggccgtgta atcttgcttt tttcagagta
     7561 gctgaaaaaa gcaggggcgt ctcaatgtga atggtcaaga aggctaagcc tggggcacct
     7621 tcttggtgtt ttttgaggta aggggctgac cagtgattga atgcaaggtg atgatggtag
     7681 ttccctgaag caatccagct agcacttgga atggtcattt tatcgcctaa atcaaaaacc
     7741 ttttgataga gaagtgaaga agccagagca tttttgacac tcagatggac atggccaatg
     7801 cgtgtgtctt gagctagtaa aaagcgcttg gggatatctg tcaactgctc caatatgctt
     7861 ttggtatccg tgggctcagt cacaccaata atttgaccat tgtcgcggat atcccaatgc
     7921 tcaacagctt tgtcatgata aatttcaatc ccattgccct caggaccgct gaggtagata
     7981 gcttcgctat agccgtgatc agctgatcct tctaaagaga tacctctggt taagaaatga
     8041 ttgagaacaa gtcccaagct atgacgatca ggaactaaaa aggatgtgtg ataaagacca
     8101 taagccttat ttgctggtaa aggtgtttgt cgtaactcta agataacggt tttaccgtct
     8161 gtagtcaatt gacgagatgt cgtgtcttgt gagagaacct gtaaaccgat aatacttgtg
     8221 taaaaggttg tcatctttgc tagatcggta acatttagag aaaccgttcc taaagagatg
     8281 gttgagttgt aagggtatgt catcctatta cctccaaaaa ctaattaaat ctatcataat
     8341 caatcagttt caaaaagaaa agtaggcaca aataagtggt ataggcacta aaaagtaact
     8401 catttgtcag ccctatcttg tttctgttct ctctaatagt ctataatggg ttataagtta
     8461 caaaaagata ctaagaggag ctgctgccta tgctgaaaaa aagaccggct tgtcccgtag
     8521 aaacaacctt atcggtaatc gggaataaat agaaattatt aatattaagg gacttgctaa
     8581 agggaccttg cgttttgggc agttgaagtc ctcaataggt ttggtcagtc aaaaggtact
     8641 tactgcacaa ttaagggcta tggaagcaga cggattggtt catcgggaag tgtatgcaga
     8701 agtgccacct cgggtggagt attccttaac agaaactggg ttgagcttag ctcctgttat
     8761 tgaagcgatg tcggattggg gccaaactta ccaagaaaaa catgccgatt tatttgaaga
     8821 aggctagagg aaagagttgt ccgagcatac tgagacttag agaagctgat agtttttaaa
     8881 aaatgatatt atcaaattct ttacagtttg ataaaattac tttttttcta caaaaagact
     8941 tgcgctcatc tcacgaatat gataatataa tatcaagtat gtttgagaaa acagaagctc
     9001 aggtcaagta agtgcacact tacaataaca cagttgataa tggggaaact cagagtcaag
     9061 aaaaagaaaa gcaagccttg cattttgcaa ggcttttttc tgtctttatt ttggtctgcg
     9121 ccgagcaaaa tctaaaaatt taaatttttc cagtttatgg cgactctcgg tgaattggaa
     9181 ttggttatta ttggaaaggt agactttgga tttgacggaa acaacatgtt ggtctgatcc
     9241 aaggtcaagt aaaattttat cacgatcggt tatttggtca atggtaacct ctttgagggc
     9301 aaagtcaatg gcgagatgga gttccttttc caaatattga taaatagaat gctctgcgat
     9361 ttcccttgtc attattggca ccaaagtttt actaaggtaa tcaatgtcta agacggaagc
     9421 cacaccctca acaacgcgtt ggcgtgtaac acgccagacc aagctgtttt tgctaaaacc
     9481 ggtcaatttt gaaagtgtct catccacaat cagtttatca atggcaatga cgttggtctt
     9541 agaatctaga tttgagtaag agacgagttc ctgataacta gttagttctg agatagggaa
     9601 catgatctga tgatgtttaa tcacttgggt gccacgtcct tgttttttga ggataagacc
     9661 tgcctttgtg agaagtgaga gagccttgcg gacggtatct cggctagctt ggtattgttg
     9721 actcaattct atttcagtag gtaaaaaatc cccttctttg taaaagtctt tgtttatttt
     9781 tgtttcgagg tctttataaa tacgttcata ctttgtcata gggtaaatta cctttccatt
     9841 tgtctatttt tttacagaca acacctttta ttttaccaaa ataatggctt ttttggcaca
     9901 aacaacttgt agacaaattt gcaatcgatt acaataaagg tgtcagttag attctatcta
     9961 agaatttgaa tatttcattt tgacgttgct tgttaaaagc aactagaaca aaggactagg
    10021 ggatgtcaca tgggaaaatt tgaacaggat gctaagagtc ttctaactgc tattggcggt
    10081 aaagaaaaca tcaaggctgt cacacactgt gcaacgcgta tgcgttttgt tttgaatgat
    10141 aataataagg caaatgtcaa agagattgaa aaaatctctg tagttaaagg gacatttacc
    10201 aatgctgggc agtttcaggt aatcattggt aatgatgttc cagtttttta taatgacttt
    10261 acagctgttt ctggtattga aggggtgtct aaagaagctg ccaaatcagc agctaaaagt
    10321 aatcaaaatg ccttacaaca ggtgatgacc atgttggctg agattttcac acctattatt
    10381 ccggcgatta ttgttggggg gcttatttta ggtttccgta atattttgga gagtgtgcct
    10441 tttgaatttc ttgggcagca ggtcgaaaaa gggaaattag tttttgatgc agctggggat
    10501 cctgtttgga atacgattgt gagggtatct cctttctggt caggggttaa ccatttcttg
    10561 tggttaccag gggaagctat tttccacttc ttaccagttg ggattacttg gtctgtgacg
    10621 cgtaagatgg gaaccactca aattttaggg actgtccttg gtatctgttt ggtgtcacca
    10681 caattattga atgcttatgc ggtagcagga acgcctgctg ctgagattgc caaaaactgg
    10741 gtttgggatt ttggtttctt taccattaat cgtattgggt atcaggcaca ggttattcca
    10801 gcccttttag ctggtctgtc ccttgcttat cttgaaattt tctggcgtaa acggattcca
    10861 gaagtggtct caatgatttt tgtgccattc ctttctttga ttccagcttt gattttagcg
    10921 catacggtat tggggccaat cggttggact attggtaaag ggatttcctt tgttgtgtta
    10981 gctggtttga ctggtcctgt taaatggcta ttcggtgcta tctttggtgc cttgtatgct
    11041 ccgctagtta ttactggttt acatcacatg acaaatgcca ttgataccca attaattgct
    11101 gatactgcaa ctcgtacaac tggtttgtgg ccaatgattg ctctttcaaa tatcgctcaa
    11161 gggtcagccg tttttgctta ttatttaatg aatcgtcatg aagaacgtga ggctgaaata
    11221 tcgcttcctg cagcaatttc tgcttacctt ggggtaactg agcctgcctt atttggggtt
    11281 aatgttaaat acgtttatcc ctttgtagcc ggaatgatcg gatcaggtat tgcgggtctc
    11341 ttatcaacaa cctttaatgt tcaggcaaat tctattggtg ttggtggctt accaggtttc
    11401 atggctatca atgtgaagta catgattcca ttcttcatct gtatggtagt agccattgtg
    11461 gtgccgatgt ttttagcctt ctttttccgt aaatcacata tcatgactaa gacagaagat
    11521 gaagctaaac tacctgagac acccgtttcg gatgctcctg tagcaactgc tccacataag
    11581 actatgcaag gaacagttat cactttaaca agccctttaa cgggtgaagt taaagcgttg
    11641 tctgaagctg ttgatcctgt ctttgcacag ggagttatgg gccaaggtgc tcttcttcaa
    11701 ccgacagaag gggtgttagt agcgccttgt gatgctgaag tatcggtctt gttcccaact
    11761 aaacacgcta tttgtttggt gacgactgaa ggtttggaat tattgatgca tattggcatg
    11821 gatacggtta acttagatgg tcaaggattt gaagctttgg tgaagcaagg tgatcaggtt
    11881 aaggctggac aaacattgat tcaatttgat atagcagcta tttctgaagc tggatacgcc
    11941 actgaaacgc ctcttgtggt gactaatcaa gatgctttta cggtaactgt tgaaggtagt
    12001 ttaccgcgtc agattaaggc taatgataag ttagcagtag cgatgaaaaa gtaggtttac
    12061 tagggagaaa acgttcagga actgagatca gttcctgaaa ctattttagg gaggaaaact
    12121 catgacaatt gataaaaaga aagtcgtcta tcaaatttac ccaaaatcct ataaggacac
    12181 gactggaaat ggtgtgggag acttgcgagg gatcattgat aaattgcctt acttacaaga
    12241 actaggaata gatatgattt ggttgaaccc tttctaccct agtccacaac gagacaatgg
    12301 ctatgatgtt tcagattata cggcggtcaa ccctgatttt gggacaatgg ctgattttga
    12361 agatttggta aaagctgcta aggagcatca gattgagtta atgttggata tggttttgaa
    12421 tcactgttcc acagaccacg agtggttcca aaaagcttta gcaggagacc cttattatca
    12481 ggatttcttt atcttgagag atcagccgac tgattgggtt tccaaatttg gtgggaatgc
    12541 ttgggcgcct tttggagata caggcaaata ctacttacac ttgtttgatg tgacacaggc
    12601 tgacttgaat tggcggaacc cacatgttcg tgaggaattg gctaaagtgg ttaatttttg
    12661 gcgagataaa ggagtgaagg gattccggtt tgatgtgatt aatctgattg ggaaagatga
    12721 agagctggtg gattgtccgg tcaatgatgg taagccagct tatacggatc gtcctattac
    12781 tcacacttat cttcatgatc tcaatcaagc cagttttggt caggatgatt cgtttatgac
    12841 agtaggggaa atgtctgcca cgactattga taactgtctt ttatacacgg ctcccgaacg
    12901 tgaggagcta tccatggctt ttaatttcca ccatctaaaa gttgattatg agaacggtca
    12961 gaaatggact attatggctt ttgattttgc agcgctgcga gacttattcc atgcttgggg
    13021 tgaaggcatg agtcagggca atgggtggaa tgccttgttc tacaataacc atgatcaacc
    13081 acgtgccctg aatcgttttg ttgatgtaac acatttccga aacgaaggtg cgacgatgtt
    13141 agcggcttcc atccatttgt cacgaggaac gccttacatt tatatgggtg aggagattgg
    13201 catgcttgat ccagattttg atagtatgga tgattatgtg gatgtggaaa gtctcaatgc
    13261 ttactcaagc ttattagtct caggtaaaag tgcagaagaa gcctttgcca ttatcaaggc
    13321 taagtcaagg gacaatgcca gaacaccaat gcaatgggat gctagtgaac atgctggctt
    13381 tacgactggt aagccttggt tagaggttgg caaatcttat cgagacatca atgtcgaaac
    13441 agaaaaagag ggacgtattt tccctttcta ccaacgcttg attgctttgc ggaaggaact
    13501 ccctattatt gctgaagggg actatcgggc tgcttttaaa gatagtcagg ctgtctacgc
    13561 ctttgaacgc catttaggtg accagtgttt gcttgttctc aatcatttct atgctggtga
    13621 ggtcgaactg gaattacctc cacgttatca acatggacag gccttaatca gcaactatga
    13681 gaaagtctct atttgtgaaa aagtgatgct gaaaccttat cagacacttg ctattttagc
    13741 tgataactaa ctaaaagcct gaggttaggc ctcaggcttt tggtgattgt cacgaaaaaa
    13801 gcagttttct catatattta tttttaaact cttatttttt ctaaataaaa acaattgaga
    13861 taagttattt tagctaaatt ttggtacaat ggaaaagatt ataagtagag tttaagataa
    13921 agattctaca aatttaaaat gatataagga gatacgaatg acaacttatc aagatgattt
    13981 ttaccaggct gtgaatggaa agtgggctga aacagcggtt attccagacg acaagcctcg
    14041 aacaggtgga ttttcagact tagcagatga aattgaggca ttaatgctag acactacaga
    14101 tgcttggtta gcaggggatc atatccctga tgatgctatt ttaaaaaatt ttgtgaaatt
    14161 ccatcgtttg gtggctgact acgctaaacg tgatgaagtt ggagtaagtc caattctccc
    14221 tttaattgaa gaatatcagt ccttaaaatc tttttcagaa tttgttgcta atatagcgaa
    14281 atatgaattg gcaggtttac caaatgaatt tccctttagt gtggcaccag attttatgaa
    14341 tgctcagctg aatgtgcttt gggcagaagc accaagcatt cttttgccag atacaacata
    14401 ctacgaagaa ggcaacgaaa aagctgagga attgcgtggt atttggcgtc agtcgcaaga
    14461 aaagctttta cctcaatttg gtttttcaac agaagaaatc aaggatcttt tggataaggt
    14521 aattgagcta gataagcaat tggccaagta tgtcttgtct cgtgaggaag gctcagaata
    14581 tgccaaatta taccatcctt atgtgtgggc tgattttaaa aaactagctc cagagcttcc
    14641 tttggatagc atttttgaaa agattttagg ccaagtacct gacaaggtta ttgttcctga
    14701 ggaacgtttt tggacagaat ttgcagccac ttattactct gaagccaatt gggatttact
    14761 caaggctaat ttgattgtgg acgcggctaa tgcttacaat gcttacttga cggatgatat
    14821 tcgtgtggaa tcaggcgctt attcgcgcgc tctttcagga acacctcaag ctatggacaa
    14881 acaaaaagca gccttttatt tggcgcaagg accgtttagc caagcgcttg gcttgtggta
    14941 tgctggtcaa aaattctccc cagaagctaa ggctgatgtg gaaagtaagg tagcacgcat
    15001 gattgaggtt tataagtctc gtctagaaac ggctgattgg ttagcaccag ccacacgtga
    15061 aaaagccatt actaaattaa atgttatcac gccacatatt ggttacccag aaaaattacc
    15121 agaaacctat gctaaaaaag tgattgatga gagcttgtca ttggttgaaa atgcacagaa
    15181 cttggctaaa atcacgattg ctcacacttg gagtaaatgg aacaagccag ttgaccgtag
    15241 tgagtggcat atgccagccc acttagtcaa tgcttattat gatcctcagc aaaatcagat
    15301 tgtctttcct gcggcaatct tacaagagcc attttattct ttagatcaga gttcttcagc
    15361 caattatgga ggaattggtg cagtcattgc gcatgagatt tcacatgcct ttgacaccaa
    15421 tggtgcttcc tttgatgaac atggtagcct aaatgattgg tggacacaag aagactatgc
    15481 tgcctttaaa gagcgtacag ataagattgt ggcgcagttt gacggcttag agtcacatgg
    15541 tgctaaggtc aatggtaaat tgacagtttc agaaaacgtc gctgatctag gtggggtagc
    15601 ttgtgcttta gaagcggcac aatcagaaga agacttctca gcccgtgact tctttattaa
    15661 ctttgcgacg atttggcgta tgaaggcccg tgaggaatac atgcaaatgc tagctagcat
    15721 tgatgttcat gccccgggtg aactgcgaac aaatgtcacc ttaaccaact ttgatgcttt
    15781 ccatgagacc tttgatatta aagaaggcga tgctatgtgg agagctccga aagaccgtgt
    15841 gattatttgg taattaggta gttgataaac cttcaaatgc ctgtgattat aaaaatgact
    15901 gattctgtaa aacacaggat cagttttttg cttccttatt ggtgtccgtt ttgacacaac
    15961 aaaaagacaa ccctcaggaa agaaggttgc cttttttaga cttatcagaa ataagtgatt
    16021 agttgttaag ggcagcagcc atagtagctg caacttctga ttcaaagtcg ttagcttttt
    16081 tctcgatacc ttcaccaact tcaaaacgtg caaaagcaat cgctttagcg tttactgagt
    16141 caaggtaagc ttcaacagtt ttgctgtcgt ccatgatgta aacttgtgca agaagagtgt
    16201 aagcttggtc aactttagtg ttgtcaagca tgaagcggtc cattttacct gggatgattt
    16261 tgtcccagat tttttctggt ttgccttcag cagcaagttc agctttgatg tctgcttcag
    16321 cagcagtaat cacatcgtct gataattgag cttttgaacc gtatttcaag aatggaagag
    16381 ctggtttgtc aaccattgca cgagattcgt tgtcaagttc gatagcgtgg ttcaattgag
    16441 caagttcatc tttgatgaat tgtgcatcaa gctcagtgta tgaaagaaca gttggtttca
    16501 ttgcagcgat atgcattgat acttgtttag caagagcatc gtcgccgcct tcgacaactg
    16561 agataacccc gatacggcca ccattatgtt ggtaagcacc gaagtgttgc tcatctgttt
    16621 tttcaatcaa agcaaaacga cggaatgaga ttttttctcc gatggtagca gttgcattaa
    16681 cgtaagcttc agcaagagtt tcacctgaag gcataacaag tgcaagtgct tcatcgttgt
    16741 tagctggttt gccttcagcg ataactttag cagttgcgtt taccaattca acgaattgag
    16801 catttttagc aacaaagtct gtttcagcgt taacttcaac aacagcagca acgttaccat
    16861 gaacgtaaac gcctgttaaa ccttcagcgg caacacggtc agctttttta gctgctttag
    16921 ccattccttt ttcacgaaga agttcaacgg ctttgtccat gtcaccatct gtttcaacaa
    16981 gtgctttttt agcgtccata acgccagcac cagatttttc acgtaattct tttacaagct
    17041 tagctgtaat ttctgccatg tgtagtatcc tccaaatgat atttgttttg gtttcaaaaa
    17101 acgagacaga gcggtttgct ttctgccccg tttggttttc gattgttaaa gacaaacaaa
    17161 gtttgccata agagttagga actctgtgct aattaagcgt tgtcgccttc gacaacttca
    17221 acgatttctt cgattgaatc tgcttgaatg tcagcttcaa aagcaacgtc tgcatcttca
    17281 ccttgacggc cttcgataat agcgtcagct aatttagcgg tgattaattt aacggcgcgg
    17341 atagcgtcat cgttagctgg aatgatgata tcgatatcat ctggatcagc gtttgtatca
    17401 accatcgcta cgactgggat accaagtttt ttagcttctt taacagcaat ttgttcttta
    17461 tgtgggtcaa caacatacat cacgtctggg atacgaggca tatcttcgat accgcccaag
    17521 aatttttcaa gacgagcgcg ttgtttgtta agaagtgcaa cttctttctt aggaagaacg
    17581 tcaaaggttc cttcttcttc catacgtttg atttctttca aacgagcgat acgtttttgg
    17641 atagttcccc agttggtaag cgttccaccc aaccaacggt ggttgatgaa gtattggcct
    17701 gcacgcgttg cttcgtcagc aactgcttca gcagcttgtt tcttagtacc aacgaacaag
    17761 atgacagcat cgtttgctgc agcatcacga acaaattcgt aagcttggtc agctaatttt
    17821 acagtttgtt gaagatcgat aacgtggata ccgttacgtt ctgtgaagat gtatttagcc
    17881 atcttagggt tccagcgacg agtttggtga ccaaagtgaa caccagcctc aagaagttgt
    17941 ttcattgaaa ttactgccat gagtagtttc tcctttataa aatgtttttt cctcttccag
    18001 acttcgactt gcaggctaac ctagcggcaa caagcccaca attggtctag aatgagtatt
    18061 tgccgcctac acgaccctac tatattatca aaaaaagagg ttaaaagcaa ggagaaatgc
    18121 tatggattcc cttatttttg agatgactag cttctttgtt tattggtaag tgttaagaca
    18181 agcttttgct cattttgggt gacacttgcc aaatcgtttt atttaagata tagtgaactt
    18241 gactaatttt tggaggcgtt ttcatgacga agggtattcg atttcaattg cttggcagtc
    18301 cccacatttt tcttgatgac aaagaacaat tttttgcctt tgccaaagca aatgctctcc
    18361 tttattactt agtggttaat ggatctgtta gccgcgaggt ggcggcgagt ctactttggg
    18421 aaaataagaa cacgcaaaca gcgaaaaaga atttacgaaa cgctatctac caggtcaata
    18481 aagtcttgca agctgatgtg attatttgtc ccaatcgcaa cctgctggtt ttgaaaaaaa
    18541 cacttgatat caaaacagat attaaccttt ttctggctga tccgctagct cacttagaac
    18601 tctaccaagg ggagtttttg cagggctttt accttaaaag tggtgaggaa tttgatcttt
    18661 gggtttcaaa aatgcgtatg cagtatgaac aggtatacct aaaagcgtgt taccaaaaaa
    18721 ttgaagaaaa gctctcttta gatgccattg aagatgtcga ggaacattta aagcagctta
    18781 ttgaacgtga tgaatttgaa gagaaaaatt atcagctctt gatgaggctt tatcagcagg
    18841 ggaattgtcc tggtaaggtc atcgaaactt attatcagtt ggctaatgtg ttggataagg
    18901 agctagggat tcagccaagt ttgcagagcc aacagattta tcaggaagtg gtcgctaaag
    18961 atcgtaatga acgcaaaatc aagcattttt tgcgcaacag taatcatttt ttggggcgga
    19021 ttgatgagat taagcagctg gaaaactatt ttgccaactg tttggcctgc caagaggtag
    19081 gagctctgct cttaattggt gatacaggga ttgggaaacg aaccctagcc agacaggtct
    19141 tagccaatca aacccaaacg tttcaaattg tcacagctaa atgttttcgt gaagaggcta
    19201 tggattcctt attgccttgg cgtaatatct tagatggcct gggagatttg gtgattcaaa
    19261 accgcttatt gaccaccaaa gcttggaagg ctgctcttaa acgctgtttt cctgtggcaa
    19321 ccatttttca agaagataac aaccaaccct ttatcaagga ccacaccagc ttgttggttt
    19381 cctttattgt tgatatttta caacatttgg cagaaatcaa ggcgctggta atccttattg
    19441 aggattgtca ctggatggat gaggatagtt tgaccttgtt gcaacgggtc atgaatcaat
    19501 tggtccacta tccgattgct tttgtcttga ccaagcatct aggaacgact cctgagctcg
    19561 gtctttgttt gaatgctttg atgagtcagg ggcgtttaga aagcatttgt ttggagcctt
    19621 ttaatcggca agaaagtttg gcatatatta acagtcaact gggtagtcag ccagtgacgg
    19681 aagaagaaat ggagcacctc tatcaagcca gccaaggcaa ccctttcttt ttgtcagaat
    19741 acactcagac cctactgcgt cacgaaaaat ttgtgcctct aacgcctgcc attaaggcta
    19801 agttgggtct taaactagct aacctaagta gtcgtgatga cgcattgtta aactatttgt
    19861 cttgttgtcg gaggcctatc cctctaaata ccctcgctca attgatgtta ctgcctttag
    19921 aagaagtgat cgagatggtg gataatctgg ggcactacta tattttggtg gaagaaagcg
    19981 taggagagga agtgttgatt tcatttcgtc agcgaattat tcaactctat agttatgacc
    20041 gtttatcttt gtcaaaaagg cgtttattgc acggacaaat tgccaaacgg ttagaagatt
    20101 tactgcctat tttgacacca agccctcact tattagatga cattgcttac cattatcagg
    20161 aatcacggca ggtgattaag gctttggaat acaaccttaa ctatctagat gctaccttgc
    20221 catttcagca tgagctgttt cccatttatt caaagagtat tggctccttg gaaaagtcag
    20281 atcgtgacca tcaacgctta atggaagagc agtttgatag gattcgtcaa agcattgcgg
    20341 atttggaact gacctatgat aataaccgtg atttccagca gttgcttatt cgtttttctt
    20401 accttgaagg ccgttatgat attcgaacag ggaggtatca agaagggatt aaaaacattc
    20461 aaaaggtcat cgctttggca accgagctaa aacagccctc cttcttgcta gaaggctatc
    20521 gccagttaat tcattactgt atccaagtgg aaaacaagcc agaaatgcgt tattacacta
    20581 gtctttcatt ggaggcagcg gttgctgcta atcattttga ggccattgcg attagtttgc
    20641 ggttaaacgg tctttatcat ttgattattg gggagttaaa tgaggcagag cgtctgcttc
    20701 aacagtcgat tgacttcttt aaggtgacgc caggcttgca agctaactat gcgattcaga
    20761 ttgctgctgc cttagattat ttgggggaga tcgcccagat tcgctatcag tttgaaaagg
    20821 ccgttgctta ccaaaaacaa gccattgcct tgaccgaaaa caagccagct gagttatcag
    20881 tgagtatttt ttatattgga ttagggattt cctactttta tttagctgat tttgaacaag
    20941 ctgagcaaat cttgagtttg gctaaggaag ctttggtcaa tcatagttat ccttggaaag
    21001 aaacgcaact tcaaatttac ctggccatga ttcaatggaa aaagggcaat tatcagccag
    21061 ccttgaccct acttgattac agagaaacct tgatgtctag gtatcgcaat ccgcgtgata
    21121 agggcttggt tttctatttg atggctgtgg tcaagtacca attgatattt caaggagcta
    21181 ccctaagtca gcaggaaaaa gaaatggcag actacctgtt gtcagaatcc tttgagtatt
    21241 attatgaaat tgctagtact aacctcaacc cttaccgaga ttgtcatttg gtgagtgagt
    21301 tgaacgattt gcgtcaacaa ttatctgcta aaagctaagg aaaaccctct gattcacatc
    21361 agagggtttt agttatgttg tgccataatc tgtacgaggt aaaagataaa ggtggctgct
    21421 aaattggcgg tgtggttatc aatatcgtgt ggtggtgaaa cctcaaccac atcaaagcca
    21481 actaattttc cgctagctgc aatgtgttgc aaaactaaga cggcaagatt tgggtcaaca
    21541 ccgagggact ggatagcact aaccccaggt gcagcaccaa ctgagaaaca atccatgtcg
    21601 atagtcaggt agaccctttc ttgcccttct aagaaacggt caatggctcg gcagaccttt
    21661 tgatggccca tttggtagat gtcttgacct gttaaaaatt gaatgccctt ggattttgcc
    21721 acaaagtcaa ataggaaaag gttgttatta tgttcttgaa tgcctaaaac gaagtattta
    21781 aagaggcgtt tgtcagcaac tgcatcgtca aacatttgtc gaaagcctgt ccctgaatta
    21841 gggcctgttt ggtcgtaagg ccttaaatca aagtgggcgt ccatattgat gacagctagg
    21901 tcatcacttg gggataggct ttggcgtagg cctaagtagt ggccgtaggc ggtttcatgg
    21961 ccacctccta agacgatggg tttgagattg aggtcacaca tccgtttgat ggctttgctt
    22021 aaactgtttt gcagttgttc caaagagcga ttggggccgt caatgttacc cacatcgtaa
    22081 accataactt ggtttcctaa atgccaaggg aatttggcta gctgggttcg tatggcagct
    22141 ggacttttga ccgctccgac acgaccatta ttgatataaa cgcccttatc acttttaaag
    22201 ccaatcaagg caaaatgcgt cccttcaaat ggggttagtg agctgtcgtt aaggtcaagg
    22261 aaagtcatga ccatgcccca tttggcagta tataagtcat cgtcgatccc accatgataa
    22321 tagctagtgg tggatgggta gtaatcttct agcatgcgcg tcatctcctt taggattatg
    22381 atagcaaaat aaaacttaca gtcaacactt tcttggcctt tgtcactggt ttttaggaat
    22441 agcagagcaa taaaatcgtc tgcttttggt cccagttagt tagtctaaag aggccatgac
    22501 ctctgccaca gcccctctag ttaaagaagt accttattca ctaaaattgg atactcaact
    22561 caactgcctg ctcaaccgct tcgaggaagc ttgggtcttc aatgactgct gatgccttgt
    22621 ttagttcatc gtagatttcg atgtgtttat cgtgttcgat aaagttgatt tccttgcgga
    22681 agagatcgta ggcaacctta gtccctttac ctagttcatg attttcaggt ttgagatcaa
    22741 gagcttggca ggctgccatg atttcagtag ccacgatgcg gcgagaattt ttaaggattt
    22801 caaaggcctt gcgagcagcg gtagtgccca tgctgacaaa gtcttcttgg ttttcacaag
    22861 atgggataga atccacgctg gctggatgtg ccaaaacctt gttttcagaa gcaagagagg
    22921 cacaagcgta ctgggtaatc ataaagcctg aattgagacc tgggtatttg acaagaaagg
    22981 atggcaattt gctgagctgg ctattgacca aacgttccac gcggcgttca gaaacatttc
    23041 caatttcaga aatggcgatg cctaagaagt caaatggctg tgccattggt tctccgtgga
    23101 aattacctcc tgaaataacg tggccatctt tacagataat tggattatct gtgacagaat
    23161 tgatttcaat gtcaactttg gatttgacat aggcgatact gtctttgcta gccccatgaa
    23221 tttgaggcat gcagcgcaag gtgtaagggt cttgcacacg agattgagta gctacggttg
    23281 tgttttggct gccttcaatg aggtttcgga tattgcgggc tgttgccaac tggccgcttt
    23341 gtgggcgaat ggtgtgaagg ttttcttcaa atggactagt aatcccgtta tgcacttcaa
    23401 gggatagggc accagctagg tctgacagtt tcaataattg aatggcgtca taggttgcaa
    23461 gggcaccgat tgcagtgaga acagttgttc cgttgataag ggcgagtcct tctttagcgg
    23521 ctaaagaaat cttgtcaata ccagctttat caagagcttc ttgaccagaa agaagctctc
    23581 ctttgtagta agctttccct agaccaagca taggaagcac catgtgagca agcggcgcca
    23641 aatctcctga agcccctaga gacccttttt caggaatgta aggatgaacc cttttgttga
    23701 gcagttccaa cagcttttca atggtggata gacgaatacc agaataccct ttgacgagag
    23761 agttgatacg gatcagcatg atagctctca cggcatcttc tggcaatggg tcaccaaatc
    23821 cactagcatg ggtacgaatc aaattttctt ggagttggac tgtatcttct ggtgagatgc
    23881 ttacgttaca aagggatcca aaaccagtgg tcaccccgta aaccacccgt ttttcactga
    23941 caatgtcatc aacaatttta cgagaggcat tcacagcttc aatagcacta tcatcaatgc
    24001 gacaggctac gccttggcga gcaatcgcaa tcacgtcttc gatagtaagg ctttcgccat
    24061 ctaaattaat cactcttgtc atagtttttc tcctagattt gttccttagg gggcatttgg
    24121 tccatttggt ggttacgtcc gtgcataagg tagtacacac tacttgcaat gatgacacca
    24181 actgcaccat aaacaaagtt cattgggttg tcaccccaaa tcataactaa actaacgata
    24241 actgcaagaa ttgggataat aggaccaaat ggtactcgga agatcacatt agcatcggga
    24301 tcgtccttcc gtaatttcat aacggctagt gctgttggaa tgtattggaa gaagcggaaa
    24361 acaacactga gttttgctaa gttttcaaat gagccagtaa gtaggagtac aatggcaatt
    24421 gctcctgaaa ccaagatagc aacgagtggt gcgccatttt gattttgctt ggcaatagca
    24481 gctggtaaga gcccttcatc agcaatggca gcaccgtaac gtggcaccat gatggattct
    24541 cccatgttaa gacctgtaat ggaaattaaa gcaccgattg agaccatcca agcgccagca
    24601 gggcctatca ttttaacaaa ggcatcttga acaggtgcat tggtcatcat gatttgagag
    24661 ccaagcatgg caatggttcc accgataatc agcatatata agacagagac gatactgatt
    24721 gatcctaaaa gagcacgcgg tacatttttt tcaggggcac gcatttcccc agcgacaata
    24781 gagagggttt caaaaccgat aaagccatag aagatataaa cagcagtatt ggagatagcc
    24841 cctaagaggt tagtccctgg ttccaactga acaaatgggg taaagttagg aagcccgttt
    24901 ttgatgaaaa aaagggtaca ggcacaaaag gcaacgattg gaattaactt agcaatggtg
    24961 gctgtgatgg tgacaatttt agaggttttc aaaccagcga tattcatcaa agatagtaag
    25021 atgattaacc caatactaag tggaatgtgc caaccttcaa aggcagggaa agtaatgata
    25081 aacattctgg caaacccagc tgccatggct gcccaagcga agatagtaac ggtccaacca
    25141 aggaagccaa cgttaaagcc aataaaatca ccaaaagctc gtttggaata ttggaaggct
    25201 ccgccgtttt tcccaaaata accagagact tctgcaaaac aaactgccaa catgatggtc
    25261 aaaatagctg ttccaaacat aacagcgatg gatgcagggc caaggccctt gtaaatggcc
    25321 ctaggtaaga gaaaaatacc agagccgata acggcattga tcccgtaaag agtggcaccg
    25381 ctcaagctaa actttgcctg ttctctttct tgttcgttca tgtgatttga cgccataata
    25441 atgctctcct ttttgtttgc aaattgcgtt caaatataat ggataaggtc gctaggaaat
    25501 gaggagatag tcggtttagg agggtccttc ttgcacctaa cgatagtgat gagctattgg
    25561 ttagcgatga gaaataggta gccttttgtg atgatgtgta gtgatttcat tggagaagaa
    25621 caggcatgag tagtgtgatg cctatcttta tcccactaag tcttatacca taagcctgcc
    25681 caaacagcta ctggagtttg ggcggggctt gtttgattgg ggcaaacttt tagatctgaa
    25741 aggctggcct cctgctcgat taccaacaag tgattggctt caagctcttg attcgcctga
    25801 ttggtcacag aataagtcag tttgcttagg gcataaagca gttgacagtc cgctttgggt
    25861 gcctcaaatg gtgtgtcaga ccagacgggt aataattgcc cttggtattg gtcatcatac
    25921 attaaattga tgtcttggca gattccacga ctgacgattc tggtatcgcc ttcaaacgca
    25981 tagggttcaa aaggagttag ggaaatctct ttagcatgac tcaaatcact caatgtgatg
    26041 ggcttgtcta gggtcattag aatcctgtga tagccatcaa gtaaggtaaa ggttgtctgt
    26101 cgtagggcca cagttgactt tgagaggcga taagagaatt ctctcttttt gtaatctcca
    26161 tcttcgggat aaaggaacaa ttggttggtt tcaccgccag accagtcagt ttggaggtaa
    26221 tcagagggcg ctttgatagt tacctttgtc atttgttctc tccttgtttc caattagaat
    26281 agtcctgtga tgttgccctc ctcgtcaata tcaattgttt cgctggcagg tacttttgga
    26341 aggccaggca tggtcatgat agcacccgtc agagcaacga taaagcctgc tcctgcggac
    26401 actttgaggt tgctaatagt cactgtaaag tcagttggtg cgccaagttt tttggcatcg
    26461 tctgagaagg aatattgggt tttggccatg caaattgggt agttgccaaa gccgaggcgt
    26521 tctaagtcag ccagttcacg tttggctgcg ggggtcaatc taatcccctt accaccgtaa
    26581 accttggtaa cgattttagt cagtttggtt tcaatgctat catcttcctc ataaacaaag
    26641 cagaattgat tgtcttgctc ggctagtgcc acgacttttt cagctaattc acggccacca
    26701 gctccgccat ttgcccaaac atcagaaatc acaacgtcaa cgccacgttt gtcgcaggca
    26761 tcatagacag cttgtaattc agcatcggta tcaagcggga atttattgat cgccacgaca
    26821 actggaagac catagacgtc ttggatatta gccaaatgtt tgtcaaggtt aggtaaacca
    26881 tccacaacgg cctgaacatt ttcagtagcc aggtttgctt ttggcacacc cccatgcatc
    26941 ttaagggcac gtatagtggc tactaggaca acggctgctg ggcgaaggcc tgacatgcga
    27001 catttgatgt caatgaattt ttcagctcca aggtcagcgc caaatccagc ttcggtaacg
    27061 gcataatcgc catatttcaa ggctagtttg gtggctagga cactattaca gccatgggcg
    27121 atattagcaa atgggccacc gtgaatgagg gctggtgtgt gttccagggt ttgcacgaga
    27181 ttaggatgaa tcgcatcctt gagcagagcg gctagggcac caccagcttt caagtcttta
    27241 gctgttacag gttcaccttg gtagttgtaa ccgatgatga ttttttcaag gcgggctttg
    27301 aggtcagaaa tattttcgga taggcacagg attgccatga tttcagaggc gacggtaatg
    27361 tcataaccat cttcacgagg aaccccgttg accttgcctt gcaagccgtc aacaatatga
    27421 cgaagctggc ggtcattcat atccaccaca cgtttccaag tgatacgtct agaatcaatg
    27481 cctaggctat tgccatggtg aatgtggtta tcaatcaagg cagccaataa gttgttggcg
    27541 acaccgatgg catgaaagtc ccctgtaaag tgaaggttga tgtcttccat tgggacaact
    27601 tgcgcgtggc caccgccagc agctcctccc ttaaccccaa aaacaggacc aagagaaggt
    27661 tcacgaaggg caataactgc tttttttcca atggcagaaa gagcatctac caatccaacg
    27721 gaagtagtgg ttttgccttc accagctggt gttggtgaga tagcagtgac aagaatgagt
    27781 ttgccatcag gtttgtcttt taaggcgacc agttgacggg catcaatttt tgccttgtac
    27841 ttgccataga gacagagcgc ttcctcgtca atccctaatt gattggcaac cttactgata
    27901 ggctccatag tgacagagtt ggctatttca atatctgata aaaccatagt tgctccttta
    27961 cttgttaaac aatatcgaga attttcgtgt agatgtcatc tgccaagtga cagcccttgt
    28021 ctaataaggc ttgtcctttt tggcgatagt cggtaacaaa gtcttcatct ttgatgccag
    28081 acagattaat caaaacattc aaccaagcgc tttgtaaacc tgcttttaag tttaaagcag
    28141 caactcctaa gtcgctagca gcatttgtat tagacttacc gacagctgtt gcagtgatct
    28201 caagtgcttc gaccatgagg gtcatcatct caaaaggtga ttgtgcagct gttttcaagg
    28261 ccttttgcat ggcagttcgt ctagcagcct tgtcttcgtc agtctctttt ggcatatcaa
    28321 aaacggcaga aaccaggttg aaggcttcgg tatctttgtc aatggctgca agcaagctag
    28381 cttgtagagc ggtgctttta gcatggatct ctgtaataat agcttgataa tcagcatact
    28441 ttttcttacc aagggtcaat tcacagacca tcttggtcaa ggaaatgcca ttagcgccag
    28501 agagagcagc agcagaacca ccacccggag caggggcatc tgagccaagg actttagcga
    28561 aatctgttaa gcttaaatca actaaaccca tagagaacct cctaacctag caaatggttt
    28621 tcaagaacct gtttagggta gtcaaagtcc tcaacttgta agtagtattc agccacatcg
    28681 attaaggcct tggctggcgc taagccgatg acttcagaac caataacatt cacaccgtag
    28741 cgacgcgctt caaatttgat ggtttcaaaa gtacggtaaa gagaacattt ttcaaagtta
    28801 accatgttca tggagacttg ggcaatatgg cggtcttcta acatgacacc gatagcctta
    28861 caatatttgt agccaccacc tgaaccgcgg ataattttag caattttatg agcaatgtcg
    28921 atattgtcag tatccaaatt aacattgaaa gcaaccaatg gcatgcgagc accaacggca
    28981 gttaccccag cagttgggtg aatcttacga tctccgtagt caggtgccca atcctcttcc
    29041 aatagttttt ctggcatgcc ttcaaactga cctttacgga ttttagcaag gttttgacgt
    29101 tctggacgtg tggcagagtc ttcataaagg aagatcggaa tgtcaagttc acggttaatg
    29161 cgttctgcga cttgtttgga aatttcgaca cattcttgtg tagtgatgtc tttgattggg
    29221 acgaacgggc agacatcggt tgctcccata cgaggatgtt caccatgatg cttggtcatg
    29281 tcaatgtttt cagaagcgta tttcaccagt tggaaagctg cttcttgaat agactggtca
    29341 tctccaacta aggtaaacac gctccggttg tggctcgcat cagaagagta gtcgagaagg
    29401 gtcactccag gaatactttt ggccgtcgct accaaaccat cgataacagc ctgattttgg
    29461 ccttctgaga agttgggaat acattcaaca atttttgcca tgttaatctc cttttatgtc
    29521 attgagttac tcattagggg aataggttac ctactttaga taacgcttac atttttagct
    29581 agcagttatt agtgaaataa ttgatctacc gctgaagtca caaggtcatc atcagccaag
    29641 tatgggatag tgatgtgatc agtacctgca tggagacggt tgtattcaat agcggtttca
    29701 atagcgtgct catttcgggc ccagttacgg cgagctacac cgcccatagt atcccaagca
    29761 atagcagatt taataatctc atcaatgcgt tcgctgccat ctaaaacaag tccgaaacca
    29821 ccattgatgg ctttaccaat accagttccg ccaccgttgt gaagagccac taaactcata
    29881 ccacgcgcag cgttaccagc gtaacattgc accgccatat cacaggtcac attggaaccg
    29941 tctttaatgt ttgaggtttc acgaaatggt gagtcggtac cagacacgtc atggtggtca
    30001 cgaccaatca tgacaggtcc aatcttgcct ttgcggacca attcattaaa tttaagggcg
    30061 acagtcacac gaccgataca gtcttggtaa aggatccggg cttgggtacc aactacgagt
    30121 tgatttttct cagcatcacg aatccagttg tagttatcac ggtcttgata gcggcggtca
    30181 ggatcgatag cttccatggc agctttgtca gtagccacca agtcttcgtg tttaccactc
    30241 aagcagaccc aacggaaagg tccatagcca tagtcaaaaa gcataggtcc catgatatct
    30301 tccacatagg atggccagat aaatccgtct ttgtcgttac gaccattctt agaaatttct
    30361 gtaataccag agtcgtaaac agacttcata aaggcattgc cgtagtcaaa gaaataggtg
    30421 ccattttcag ttaacgtctt aatagcttca aaatgccgtg ccaaggtatc atcaaccatt
    30481 tggtggaagg tatctttatc ttctgccaag agccgggttc tttcgtcaaa gctaatacct
    30541 actgggcagt agccaccgtc ataaacgttg tgacaagagg tttggtcaga caaaagatca
    30601 acatgaatct gcttgtcatt gacgtactct aaaagatcaa cgatattacc atggtaagca
    30661 atcgaagtgg actctttagc atctatggct ttttgggcta attgcagagc ttcttcaggg
    30721 ctctcagcaa tttgggtaac ccagccttgc gaatgacggg tttcaatccg agattggtca
    30781 acttcagcaa taatggcaac tgctttagca atttcagcag ccttaccttg tgccccactc
    30841 atgcctccta aaccagatga gataaagagt ttaccggtca aatcaccatc gtcagccacc
    30901 ccaagtttga gacgaccagc atttaagagg gtattaaatg ttccatgaac gattccttgt
    30961 gggccaatat acatccaacc acctgcggtc atttgaccat agttggtgac acccatctct
    31021 tcagcgattt cccagtcttt catgttgtcg tattcaccca ccaaaaggcc attagtaata
    31081 atcacacgag gcgcttcagg tttggattgg aaaagaccaa ctggatgacc agactcaacc
    31141 accaaggttt gttcatcagt catgacttct aggtattttt taatcaaaca atattgcatc
    31201 cagttggcac aaacagaacc agtttctcca taagtgacta gttcgtaagg gtacaaggca
    31261 atctcaaaac tcaagttatt gtcaatcatg acctgcatgg ccttggcagc tgtacaattt
    31321 cccttgtact cgttaatggg tttgccgtaa atgcggtctt ttggacgcca tctgtaacca
    31381 tagatgcgtc cccttgtttt gagttcttcc aaaaattctg gaatgacttc ttcgtggaac
    31441 ttcgtaggta catagcgtag ggcatttttc aaggcgattt cggtctgagc ctgggtcaat
    31501 cgaaaacctc tgtctggtgc tcttcggata ccttctttga agacagtctt ttccggtaaa
    31561 acatcgtcta acttaacagt catagcggca gctatgtcag tttcactgta aaatgacata
    31621 gaaaactcct cctcaactcc tttttattgt cgagattagt ctaacttaga ctagtctata
    31681 aaaagtcaac cacgctttga aatgcgaaaa aagtctaaaa aaaaatcaaa acctcatttt
    31741 ttgactaaaa tttgacgctt aatcagtaca cttgaggcat gacagataaa gtcagtcaga
    31801 gtttaattgt tgttaccaaa gttgcagaga tcgcaactat tgagtgggtg aggggggact
    31861 agtaatggct attaatcagt tgacaaacga tgttaaaaaa ggaggttttt atggttgctg
    31921 atgtcttatt aacacatttt aatcaactat tttgtctaaa tgatccaggt catcctttaa
    31981 ctggtcaaga aatgaaaaaa gccactatcg ttgaagatgg ctatatagcc atcaaagacg
    32041 gcctcattgt ggctcttggt tctggtgaac cggatgctga gcttgtcggt ccacagacta
    32101 ttatgcgttc ttataaaggt aaaattgcaa cgcctggtat tattgactgt catacccatt
    32161 tggtctatgg tggcagtcgg gaacatgaat ttgccaagaa attagcaggg gtgtcttact
    32221 tggatatttt agctcaaggt ggtggtattt taagcacggt gagggccact cggtcagcca
    32281 gctttgacaa cctttatcaa aaatccaaga gattgctaga ctacatgttg cttcatggag
    32341 tgactactgt cgaagcgaaa agtggctacg gccttgattg ggaaacagaa aaacgccaac
    32401 tggatgttgt tgctgcgtta gaaaaagacc atcctattga tttggtgtct acgtttatgg
    32461 cagcccatgc gattcctgaa gaatacaaag ggaatcctaa ggcttatctc gatgtgatta
    32521 tcaaggatat gcttcctgtt gttaaagagg aaaatctggc agaattttgt gatattttct
    32581 gtgaaaaaaa tgtttttaca gctgatgagt cccgctatct gttaagcaaa gccaaagaaa
    32641 tgggcttcaa gcttcgtatt catgcagatg aaattgcgtc tatcggcgga gttgatgtcg
    32701 cagcagagct cagcgcagtt agtgcagagc atttgatgat gataacagat gatggtatcg
    32761 ctaagttgat tggtgctggt gttattggta atttgcttcc agccaccacc tttagtttaa
    32821 tggaagacac ttatgcccct gctcgcaaaa tgatcgatgc cggcatggct atcactctct
    32881 caacagatag taatccaggc agttgcccga ctgctaacat gcagtttgtg atgcaattag
    32941 gttgttttat gttacgttta acaccgattg aagtcttaaa tgctgttacc attaatgcgg
    33001 cctactctgt caatcgtcag gagagggttg gtagtttgac agttggtaaa gaagcagata
    33061 ttgccatctt tgatgcccca aatattgatt acccatttta tttctttgcc accaacttga
    33121 ttcaccaagt ctataaaaaa ggacaactca cggttgatcg aggtcgtatt ctttaaaaaa
    33181 tttcaaaaag aagctttgag cgttagctca aaacttcttt taaatatgct attttattga
    33241 cgaatcaagt agtcaaaggc accgatggca gcagtagcac cagaccccat ggaaataatg
    33301 atttgtttat aagctgaatc agtacagtct ccagcagcaa agataccagg aatattggtt
    33361 gacccatgtt tatccacaat gatttcaccg cggtcggtta ggttgacacc actatctttg
    33421 agccaagctg tgtttggaac aagaccaatt tgaacaaaga ccccttcaag gtcaaggtgt
    33481 ttgtcttcac cgctatcacg ctcagtgtag ctaagacctg taacatggtc ctctccaaca
    33541 atatccttag tagcaacatt tttgatgatg gtcatattgt tagtcttagc tgcgcggtct
    33601 tgaagcactt tgtcagcttt aagttcaggc aagaattcta aaacgtaaac gtgtttagca
    33661 agaccagcca agtcaagggc cgcttctaat ccagagttcc caccaccgat aacagcaaca
    33721 tctttgcctt caaagagagg accgtcacag tgagggcagt aagtcacccc tttattacgg
    33781 aattcatctt caccaggaac attaatgtta cgccatttgg ccccaagagc taagatagca
    33841 gttttggctt gtagaaccgc accattagct agagtaacct caatgttttc ttttttctca
    33901 atagaagtag ctagttgtgc tttgataata tcaacatcat aagacttagt atgggcctcc
    33961 acttcggcca ttaattttgg tccttcagtg taaagggtac caatcatgtt ttcgatgccg
    34021 accgtttcca tgacctgacc accaaaggtt tcagcaagta aacctgtttt tagtccttta
    34081 cgagctgcat agatagcagc gctattgccc gcagggccac caccaataac aaggacatca
    34141 tagaggcctt tatcagcaaa ggcttcctca gaaagtgggc cagcgatttg ttctaagagt
    34201 tgctcaatgg tagcgcgacc agaagtgaat tcttccccgt ctaaaaagac agtagggaca
    34261 gacataatgc cttttgcttt cacttcatct tggaacatgc cgccttctac catagtgtgt
    34321 gaaatcttgt cgttcaagac ggacataatg tttaaagctt gaacaacatc tgggcagtta
    34381 tggcaggtta agctgacata agtttcaaaa tgcaacggac ggtcaatggc cttgatgcga
    34441 tcaataacat cttgatccac ttttggagca cgtccagata cttgcaagag agcaagaata
    34501 aaggacgtca attcgtggcc taaaggaaga ccagcaaaga caaccccact accgtgacct
    34561 tttttcgcaa ccttaaagct tggttgtcgg tctaaagtga tgttttcaat agaaatacgc
    34621 tcagacatag cagctatttc ttccacaaag tctttgactt tttgagactg ctcattgtca
    34681 ccaagggaaa cttgcaaaac aagatcagct tctaacaggg tgaggtattg ggcaagttgt
    34741 tctttaatat caggacttaa tgccatagct ttcctcctaa aatttattaa attttaccaa
    34801 ctaaatcaag acttggtgtc aaagtttcag cgccttcttt ccatttagct ggacaaactt
    34861 cacctggatg tttacggacg tattgggcag cgtgaatttt atcaatcaag gtgctagcgt
    34921 cacgtccaat accatcagca ttaatttcca tcatttggat aataccatct gggtcaacga
    34981 taaatgttcc acgttgagca agtccgtctt cgccaagcac ttcaaaggct tgtgaaataa
    35041 ggtgtgaagg gtcaccaatc atagggtatg tgatagtgcc aaccacatct gagtcatcat
    35101 gccaagcttt atgaacaaaa tgagtatcag tagagacaga ataaacttct acaccaagag
    35161 atttcagtgt ttcgtattgc tcttgaaggt caccgagttc agttgggcaa acaaatgaaa
    35221 agtctgctgg gtagaaacaa aaaactgccc attttccttt aacgtcttca tttgtaacag
    35281 tgatgaattt tccatcgtga taagcttgag ctgaaaattc agcaatttct tttccaatta
    35341 gagacatata gttgtcctcc ttttttatag ttttatactt gtattataaa agaacaacaa
    35401 gattatgtct actcagaaac ccttgatttt actgggaaat cagcgattgt tttctgacaa
    35461 ttcagttgtg aaataaatca cattaattaa aatgattcta aataagctga agacgccgtt
    35521 aaatcaaagg ttaatttaat tataatctac agaaaatgta attgttatta aagcgtttac
    35581 aaaaaaactt ttttgattcc gttaaggcaa cttaatatta tggttaccta atcgctaata
    35641 ttgtaaccta ttttggcatg agatcaggga atggctgtta tattaattgg atatgtcttg
    35701 tgcaaatagt gcttgacgga tttgtggaat tagggtaaaa taatctttgt tgtggcggta
    35761 tagccaagtg gtaaggcacg gctctgcaaa agcttgatcg tcggttcaaa tccgtctacc
    35821 gccttttata tacaaaacaa gccttgatta atttcgtgaa aacgttgtta aatcaaggtt
    35881 tttatttttt gcgacaggat aaaaaaagag aaaaaaagaa ataaagtcgg tcaaaagtcg
    35941 gtcaaatttc ccgaagatgt cttttatagc ctgattatta ggtatgaaaa atactatggc
    36001 caaaattggt aaacgattgc aaataaaggt cagagttctt acccccttaa acgatatgcg
    36061 ttaaaagtta gttgaactgc cgtgcaccta acgatagaca cggtgatgtg agagcgagta
    36121 gagttgaatc tctacttgtt tatcttacca tagtcagctt tataaagtaa ccacccatta
    36181 caatgcaact atattcttaa tgtttttaag catgttattg acaagtgtta taaaatgtgt
    36241 tactcttagt gagtaaatta gtttttgagt tagtatttgt gtttcaacat ctttatttct
    36301 ctctattttt acaaatgatt tttagaaagg aagtggatgt atatggcaca aggtacagta
    36361 aaatggttta acgctgaaaa aggttttggt tttatttcaa ctgaaaacgg tcaagatgtc
    36421 tttgcacatt tttcagccat ccaaactaat ggttttaaaa cgttagaaga aggacaaaaa
    36481 gtggcatttg acgtcgaaga aggtcaacgt ggacctcaag cagtcaatat cactaaattg
    36541 gcctaatctg gttaaagtaa ctaaagagaa gcagatgttg gaaacaacaa ctgctttttt
    36601 gatttctacc agttaccttt aatgattaag agttgcgttt aaggtcttgt atttgttata
    36661 ataatagtca gttttagtca aaatgtattg acgtggtgct actaagtttt tagagtagcc
    36721 cgcaagcaaa ggagtgacag catgccaacc aaaaatactt cagacagcat tgaagagtat
    36781 attaaagaat tattagctaa gtcaggaata gcagaaatta agcggtccat gctagcagat
    36841 tcgtttcaag ttgtcccaag tcagatcaac tatgtcatta aaacccgttt tacggagagt
    36901 cgaggctatg aagtagagag taaacgaggt ggtggaggct atattcgtat tgccaaggtt
    36961 catttttcag acaaacacca tctgattggc aatttaatgg caactattga agactgtatc
    37021 agtgagcaag ttttcacgga ctcgatacaa ttgctttttg acgaacactt attgacagag
    37081 cgtgagggaa atatcatttt ggctgtggcg tctgatgatg ttttaggaac tgatggttca
    37141 actattcgtg cacgaatgct ctatcgctta ttgcaacgaa ttgacagaaa gggaagcaat
    37201 taatgattat gtattcaacg aagatgcaag acatttttag acaggcgcag ttccaagctg
    37261 ctcgctttga tagccattgc ctggaaactt ggcatgtttt gttagctatg gtagctgtag
    37321 ataattcttt agcaaatatg attttaagtg aatatgatgc ccaagtcgcc atagaagaat
    37381 atgaagctgc agctatttta gccatgggca aaacccctaa ggaacagttg tctcgtgtag
    37441 acttcagacc tcaatctaaa accttgacta acttgttagc ttttgcgcag gctattagcc
    37501 aaatcactag ggatcaagaa gtcggctctg agcatgtctt atttgctatt ttattgaatc
    37561 cagatatcat ggcgagtcgt ttgttagaaa tagcaggcta tcagataaaa gataacggca
    37621 atgggcagcc gcgattagct gacttgcgaa aagcaataga acgtcatgca ggttacagta
    37681 aggaaatgat taaggctatt cacgaactac gtaagcctaa aaaaacgaaa acacaaggga
    37741 ccttttcaga tatgatgaag ccaccaagta cagctggtga attgagtgat ttcacaagag
    37801 atttgactga aatggcaaga caaggtttgt tagaatcggt gattggacgt gaccaagaag
    37861 tatctcgtat gattcaggta ctaagtcgta aaacgaaaaa caatcctgtc ttggtaggtg
    37921 atgcaggtgt tggtaaaact gcgcttgctt atggccttgc tcaacggatt gcaaatggcg
    37981 ctattcctta tgaacttaag gagatgcgtg tcctagaatt agacatgatg agtgtggtag
    38041 caggaacccg ttttcgtggg gattttgaag agcgcatgaa tcaaatcatt gatgatattg
    38101 aagctgatgg tcagattatt ctttttgttg atgaactaca tactattatg ggttctggca
    38161 gtggtattga cagtacactt gatgcggcta acattttaaa accagcatta tcgcgcggta
    38221 ctcttcatat ggttggagca acaactcaag aagaatatca aaaacatatt gaaaaagatg
    38281 cagctctttc gcgtcgtttt gctaaaatat taattgaaga acctaataca gaagatgctt
    38341 atcagatttt gatgggccta aaattatctt atgagaccta ccataatgtc tcgatatcaa
    38401 atgaggcagt taaaacagct gtaaaaatgg cacaccgtta tttaaccagt aaaaatctcc
    38461 ctgattcagc tatcgattta ttagatgaag ctagtgctgc tgtgcaaaac atggtgaaaa
    38521 aatcagctcc tgagacttta acaccaatag accaagctct tatcaatggt gatatgaaaa
    38581 aagtatctcg cctcttagct aaagaagcaa aaggtcagat gagaaaacca acaccagtga
    38641 cagaagatga tattttggca accttgagta agttatcggg aattccactt gaaaaactga
    38701 cgcaagctga tagtaaaaaa tacctcaatt tagaaaaaga actgcataag cgtgtgattg
    38761 gtcaggatgc tgctgttacg gctatttcaa gagccattcg tcgcaatcag tcaggtattc
    38821 gaacaggaaa acgtcctatt ggatcattta tgtttcttgg cccaacagga gtaggtaaga
    38881 cagaactagc aaaggccctt gcagaagttc tctttgatga tgaagcagcg cttattcgtt
    38941 ttgatatgtc tgagtacatg gaaaaattcg cagcgtctag gcttaatgga gcacctcctg
    39001 gttatgtcgg ctatgatgaa ggaggtgaac tgacacagaa agttagaaat aaaccttatt
    39061 cagtcttgct ttttgatgaa gtggaaaaag cacatcctga tatttttaac gttctccttc
    39121 aagtattaga tgatggtata ttgactgata gtcgtgggcg taaggtcgat ttttcaaata
    39181 ctattattat catgaccagc aatcttggcg caacagccct gcgtgatgat aaaacggtcg
    39241 gttttggggt caaaggcatt caccaagacc atcaagctat ggagaaacgt attttagaag
    39301 aattaagaaa aacttaccgc ccagaattta tcaatcgtat tgatgaaaaa gtggtctttc
    39361 atagtctgac ccaagataac atgcgcgatg tggttaaaat catggtacag cctctgatta
    39421 ctacattggc agaaaaaggt attaccctta aaattcagcc tttggccttg aaacatttgt
    39481 ccgaggtcgg ctatgatgag catatggggg caagaccatt acgtcgaacg ctgcaaactg
    39541 agatagaaga taagctatca gagcttatcc tttctcgaga attgacaagt gggcatacgc
    39601 taaaaattgg attatcatat ggcaaattaa cgtttcacat agcttaattt ccatataaaa
    39661 ggtggatcat ccttgatgtc accaaaaaaa gaggttattc ttacaaaaat aacttctttt
    39721 ttcttgacta tttttgacca agtgataaaa tagaatataa agttagcact cgatgaacat
    39781 gagtgctaac tttactaaag attcttttat tggaggaaaa tttcatgtta aaaccattag
    39841 gtgaccgtgt ggtcgtaaga tttgatgatg aaaaagagca gacagtcggt ggttttgtcc
    39901 ttgcaggcac tcataaagag tcaacacgaa aagcgacagt cctcgctgtc agtgaaacgg
    39961 gtgttcgcac tattacaggt gatagcgtgc taccttcagt ttcagtgggt caagaggttt
    40021 tagttgaaaa tgggcatgat ttagaagtaa ccgtagatga tgagaaagtt tctatcatcc
    40081 gtgaatctga catcattgct attgttacaa aataaaacga caaatctcta aatagaaaga
    40141 aggattgaat atggcaaaag atattaaatt ttcagcagat gcgcgtgctg ccatggtgcg
    40201 cggagttgat atgttagcag ataccgtcaa agtaacgctt ggtcctaaag ggcgtaatgt
    40261 tgttcttgaa aaagcttttg gttctccctt aattactaat gacggggtaa ccattgctaa
    40321 agagatcgaa ttagaagatc attttgaaaa catgggagca aaattggtgt ctgaagtggc
    40381 ttctaaaacc aatgatattg ctggtgatgg gacgactact gcaacagttt tgacacaagc
    40441 cattgttcat gaaggactaa aaaatgtgac agcaggtgct aatccaattg gtatccgtcg
    40501 aggcattgaa acagcaacag caacagctgt tgaagccttg aaagccattg ctcaacctgt
    40561 atctggcaag gaagctattg ctcaggtcgc tgcagtatca tcacgctctg aaaaagttgg
    40621 agagtatatc tcagaagcta tggagcgtgt gggcaacgat ggtgtgatta ccatcgaaga
    40681 atctcgaggt atggaaacag aacttgaagt ggtcgaaggc atgcaatttg accgtggtta
    40741 cctgtctcaa tacatggtca cagacaatga aaaaatggtt gcagaccttg aaaacccatt
    40801 tatcttaatc acggataaaa aagtgtcaaa catccaagac attttgccac tacttgagga
    40861 agttcttaaa accaaccgtc cattactcat tattgcagat gatgtggatg gtgaagccct
    40921 tccaaccctt gtcttgaaca agattcgtgg tactttcaat gtggttgctg tcaaagcgcc
    40981 aggatttggt gatcgtcgta aagctatgct tgaagacatt gctatcttga caggtggtac
    41041 agtgattaca gaggatctag gacttgaatt aaaagatgct acaatgacag cccttggaca
    41101 ggctgctaag attacagttg ataaagatag cacagtaatt gttgaaggtt caggaagttc
    41161 agaagctatt gctaaccgta ttgcactgat taaatcgcaa ttagaaacaa caacttctga
    41221 ctttgaccgt gaaaaactac aagaacgttt ggcgaaatta gctggtggtg tagctgttat
    41281 caaagtagga gctccaacag agacagcttt aaaagaaatg aaacttcgca ttgaggatgc
    41341 tctaaatgcc acacgtgcag ccgttgaaga aggtatcgtt gctggtggtg gaacagcact
    41401 tattacggtg atcgaaaaag tagctgctct tgagcttgag ggcgatgacg ctactggacg
    41461 taacattgtg cttcgtgctc tagaagagcc tgtacgtcaa attgctttaa atgctgggta
    41521 cgaaggctcc gtagttattg acaagttgaa aaacagccct gcaggaacag gatttaatgc
    41581 tgcaacaggt gagtgggttg atatgattaa aacaggaatc attgaccctg tcaaagtaac
    41641 acgatcagcg cttcaaaatg cagcttctgt agctagtctt attttgacaa cagaagcagt
    41701 tgttgctaat aagcctgaac cagctgcgcc agcgccagca atgccagcag gtatggatcc
    41761 aggaatgatg ggcggcttct aagctctcta tagcattaag gattatgaaa aagaagttga
    41821 gactaaaggt ctgcttctta ctatgaaaaa agaacaaaga ttggatttcg actcatgata
    41881 tcccatcttt gtttttttag ttgtgatata aaatgccaat ctttgtggtt acagactttt
    41941 aatgtattgg aaaatatatt gtttttcttt gtcatgtgct atcatggagc caatgaaaag
    42001 ttattcccat atatgcgtgg tggaggtctg tgatgaatca ttttggagag atttttaaaa
    42061 cctttagaga atcaaaggga ttacgattaa aagatgtcgc aaaggctggt atatcaacct
    42121 ctcagctgtc gcgtttcgaa aaaggggaga cggatttaac catatcgaca tttatgctga
    42181 ttttggatga aagtaacatg tccattgatg agtttatgta tgctgtccat gattttcatc
    42241 gtgacgactt aaatgaactc ttatcaaaaa gtgagggatt tcgtaacaat tcaagatagt
    42301 gatggcttga agcagttact tcatgctcaa ctagcatcaa ctgataagaa ggaaatgttc
    42361 acggatatct tttggcatat ctagcatgtc taagtctgct atggcatgcc attttgggag
    42421 tccctcacgc gactctgtca gtagctctcc ttcaaaggat tcacatagaa agtcgtaata
    42481 gacatagcac tctttttttg tcaggcttga taaagctgga aatacccttt aattgaaggt
    42541 ttaaagctgt cagacctatt tcttctttta gttctcataa agccgcttca aagaaagatt
    42601 cacagggctc gactttacct tctggctgga cccatcctgg taagttatcg tgttgtctat
    42661 ggagtcataa aatcatatcg ttatgtttga cacacatatt gccccagtct ctaaccgttg
    42721 ctatcaccag attcaccacc ttttagtata agaaaaaagg ggtgaaagag gtttcttgtt
    42781 gtttttttgg cttaagattt ctttaagtct tatctagtat actaatgtca ttccttaata
    42841 ggataagtat ttggttgtag aagtatcgtc ttaaactaat gctatctcaa ccgattccca
    42901 acttattcac ccctcctata ccgataaggt ctcacaaagt gtgagacctt attttttgac
    42961 ttcagctcta gttatggaga aacttgttga tacaagcttt tttgggttat gggttatggt
    43021 attatgatct attcaagcct ttcttgtttt ggggtttttc ttcaaccaac ttggcttcaa
    43081 tagcttttaa gcgtttgaag gttttttcag cgcgatctag tgaaatctta tcagcttttt
    43141 cttgagcagc tttggggtca ctgacgacta agtcactgat ttctttggtg cttttgtctt
    43201 gttcggctat ccaggttttt tccaagcctt tcatctcatc aatcacttta gttccaaatg
    43261 gttttggatg agcagccacg agatcattaa tgtgtgacac cgtccaatac catgacttat
    43321 cgttatattg ggtgcttttt tcttgatagg cttcataggt tctactgata ttgccaaggt
    43381 atggcaagta aggggcatta cgaggactgc caatagatag ccacatgaca ccaccaccca
    43441 attcagcagg aatgtctttt ttcagttgga aaatatgagc ttccatgaca ttaggatttg
    43501 agatggggta agcataacct ttaacagctt ttttggattt tggtttaccc ttaccgtcta
    43561 atgccatctg atcaagtggt ttaagatcca gcccctcaaa acgattacgt tgcagtttca
    43621 tcgcatcttc tagactaaag gtcttatcag tgctttggag caactcataa ttgctgtctt
    43681 tataagttac ttttgaatca gggtcaagtg atttaatccc tgagaaagag cgagagcggt
    43741 tggcatcgtt tagtggtgga ttgtaagatt tggcaatatg aaatttacca tcaacttcgg
    43801 tataagattt ggctttttta gtgacttttt ccacatcttc tgaggcaatc gtattttcct
    43861 tatcgttgaa atcgacatgt ccgagataga aggtatttgg aaaaacagcg tatttatcat
    43921 ctgggaattt gatggcaacg tattggtgac cagagagaat ttccatgtac cagatgccat
    43981 ctttgtcagc caaggtaaca atatttcctt cagcagctcc tttttcagtg actattttag
    44041 caatcaatgc gacaccttca cgggctgttt tgacacttgg taaaatgaca ctggccatag
    44101 atgattccgc taagccattt ttgacgtaag gatcaatttt ttggatggca tcattagctg
    44161 aagctgatac tgttgcagac atagagacgc caaactcatt aaaaccagct tcgtcataaa
    44221 cgcctttatt aggtgttaca tcaggaatcg cactatagcg ataagaatgc tcaggcaatg
    44281 ggtactcaaa accattagag gggtctttcc atttttcgcc agcaggattg tcctttgcta
    44341 gacgtacaat gaagttttta ttatgatgtg gctcaagatc ttctgttcga ccataaagaa
    44401 gagaaccgtc tttggttaaa tctttgccaa taataaaacc agtacaagca taactaacac
    44461 tttgaagcga aaaggctgtc agaatactta aaactccaag tgatattttt ttgtttatca
    44521 tgcgaatcct cctagtaaac gataacgctt tcacagacat tataaaatgc tctttttaaa
    44581 aattcaagtt ttttatgaag tgttttgaaa ttgttagcta tctaaatatt atgagaattc
    44641 tctcttgaat tttggcttaa cggcccctaa aaacgtatag gcagtgaact atctaggttt
    44701 cttcgaaaat ccattagcca tttatgatat aatagtaaag aaaaacatag aaagttgggg
    44761 tctgttgatg accaaaccat ttcatcataa gaaactaaaa caaataacta taatagctgc
    44821 aactagcctt tttttattcc tgatcggtgg tgccttttac tactctaaaa atcattgtat
    44881 taatgcctat cttaaagctc gatcagccca atcaggacca gtttttgaaa atatcaaagc
    44941 atatctagtc tgggatgata ctaatgagca gatcacaaat gacgaggcga tgtatactaa
    45001 gtttagaagg tatagtcaaa aagaattgag gcaaaaaaag caggatttaa aagccgctag
    45061 tcaagatagt gccgttcaag taaagtctgt tggtcgtcgt ttttggattt ttcctgatta
    45121 tcggattgcc ataaaaccca tggatttaac gataaaaacg aatgtgcctc aagcagacgt
    45181 tcttttaaat caaaaaaaag ttgctgtttc tgattcagaa cagttctcag taaagcttga
    45241 tcggctacca acggcagaat ataccgcaag tatcagaggc aaacacaacg ggcgaaacat
    45301 taaagtcaac aaatcatatg atggtgataa tcccgtgcta gatttgagtg tgtcttttag
    45361 aactttttta gtaacaagca atgctaagca aggagatctt tacttcgatg ataaccatat
    45421 tggcacatta aaagatggtc aattacaagt agaagattac cctgttacag aaaacgcaca
    45481 agcttatatg aaaacaacat tcccagatgg tgagttaaga tcacaaaaat atgctctagc
    45541 tgatgttgaa gaaggagcaa ccctggagat tttagttaca gatcttttag aagaggacaa
    45601 agcaggggag ctattagtat cagcttttga tcagctgatg cactacctca gtacaggtca
    45661 agactcatct aacttacgta gcgtctttga ggcagggtct agcaacgcat tttatagggg
    45721 attgaaagag tccataaaag cgaaatttca gacagataca agaaaagcca gccgtctcaa
    45781 tattccatct atccttttga caacaatgac tcaagtgggt aaaacaactt acgtgcttga
    45841 tttcacagct acctacgaat ttttgtatga caactcaaca gatcctgagc agcatacctc
    45901 tggacatatt aatcaagact tgactggaaa agtgactgta aaaaaagttg gacagcatta
    45961 ccttatcagc cagtccggct ctaaaaatat tactgttgtt aaagaggaca atcaactcaa
    46021 agcgccatct gtctttcctg agtctatttt gggaacgtgg acaggccaag ccaatggttt
    46081 aagcatccat atgtctctag catcagatgg aacaattacg actaaagttg aagatcgaaa
    46141 aggcaaccgt tctaaagaaa ctcggacagc taaaattagt aaagttgaag acaaaggcaa
    46201 tggtttttat ctttatacgc cagatcctgg aagtgacata agcgccttag ctccagaagg
    46261 aggattgggg ggtgcaaatg tcaaatatgc ttatggtttc aaaatatctg gtaaaacagc
    46321 ctctccagtg gtgtggcagg cagcattaac acatgaattt gattatacca agccactttc
    46381 gggagtaact ttgcaaaagc aaccataaag gatgcaaagc cacaaagaac agtagaaaca
    46441 atgttatcac tcaaatacag tgctatgaaa acagataaac tcaaaaggct aggagattat
    46501 ttcctagcct tttgagcgtt taagactgcg tcaaatgtag ctgatttagc ttgcacgcaa
    46561 atgtcttctt gggttagagg gtgttttaaa cgtaattgat aagcatggag catcagtcga
    46621 gcacaatctt tttttccatt agaatacaaa ggatcaccaa ataaaacatg accttgatgg
    46681 gctaaatgga ctcgaatttg atgagtccgt ccagtttgta attgacaatt gagtaagctt
    46741 gccgttttgt ggaagttttt gactagagtt acctcagtaa tagctttctt gccatttatc
    46801 ggatcgacaa cacgttttct gcggtcatgt cgatggcgac caattggatg atggtaagtt
    46861 accctaggac tgtctaagga tccgtgaact agtgccaaat attctcgatg gatgtctctt
    46921 ttttctaaaa gacgattaag gattggtaag ataaaaggtg ttttagcaaa taaaatggcc
    46981 ccacttgttt ccttatccag acgatgaacc acatagcagg tctgtcccgt gtaagcagac
    47041 acgtggttga gcagcgccaa ctctgttgga tcattgccgt gtgttttcat cccttcaggt
    47101 ttgttaacaa taatgatgtg ctcatcttca taaaggcagg ttactttttc ggcctgcccc
    47161 atcacgataa tcttttcagg ataatcttcg tgatcgaaaa aaagtttgac ctgatcaccg
    47221 tatttaacac aactttgcca gttaacagga tgaccattaa taagaacatg ttttttagtt
    47281 ctcagaaaat gcctaatttt acggggaatt aacaattgtt cctctaataa tgctttgacc
    47341 gtcaattctt caaagggatt tttcagtgtg acagtaaacc cctttgatgg tttatttgtt
    47401 gtcttcattg agccagttat ggtatttttc aacaaggttg atagccattt gggtggcaag
    47461 agcagcagag aaagcttcag taccttcacg ctcgtcatta gctacctcca agcgagtctc
    47521 atcgtaaatg gcttttagac tttctgcgga taaggtttct ttaaaagctt ggaatttatt
    47581 cattggttaa acccgtcctt ctatgtttaa tgtgagctcc tgattaatgc aaggaattca
    47641 atgctattat agcatgtttc taatcaaaac gtgccactca aaaaggtaaa aacgttattt
    47701 tgctaatcca tctaataaga aagtgtctta aataagacct cttgatagag tttgtaacag
    47761 aaatgatatg aaactaggtg ctaacgcaga aatagaaaac aactaacgtg ttgcgaagtt
    47821 ggaacagtca taaaaaaata gcaagataaa acttatcaac acacagttac ctaagacgat
    47881 gagtcaaaca ggtatgttct ttcaaaacaa ccccatgagg ttgaacgacg tatcggaaaa
    47941 atacggatta gtttggcctt atgataggtc cttctctatc gtaaaagaag tcaaccaaag
    48001 gtttttaata taaaatatta agaaaaattg ttataattat gataaaaaca taatcgtaaa
    48061 atagaggaaa aacaatgaaa acaattagac gttatgatgt taacgaagat agagggcata
    48121 caggccttgt agaagcagga gatttctatt atttaaacta ttgtgtcggc aatgttggac
    48181 aagacattga aagtcagatt aatggagcct ttgacgagat ggagcgccga ttagcattgg
    48241 tggggctcac attagatgca gttgttcaaa tggattgtct atttcgagac gtttggaaca
    48301 tacctgtgat ggaaaaaatg attaaagagc gctttaatgg cagatatcct gctcgaaaat
    48361 cgattcaaac ggaatttgca catcacggtg gacctcaagg actactcttt caagtggatg
    48421 gtgtggctta ttcaaaacat atttcgatga cctaatcaag gttactttaa gatcatagtg
    48481 gtataataac gttatgagat ttctagaact tttacaaaag aaattttttc ctaaagcata
    48541 tcaggaaaaa caattcttaa tgcatcaaaa aacgcgttta acgccacaac acaatcaaaa
    48601 gcagtattcg ccaaatgcca atcatttgga ctcatcagct accaaaaact cagaacaaga
    48661 ccctgcaata gctctgcaac gcagtagagc ctatgaagga agccctaaaa gtcggcccgc
    48721 ttggttgcaa aagttggaag ctgttttgcc gtctcctcaa catccaattc ggcgtttttg
    48781 gcgccgctat cacatcggaa aactgctaat gattctgatt ggaactcttg tcttactctt
    48841 aggatcatac ttgttttact tatcaaaaac agctaaagta tctgatttac aagatgcctt
    48901 gaaggctaca actgttattt atgatcacaa aggagagtat gcaggcagtt tatctggtca
    48961 aaaagggagt tatgttgagc tcaacgctat ttcagatgat cttgagaatg ctgttattgc
    49021 cactgaggat aggacttttt acagtaatag cggtattaat cttaaacgct tcttattggc
    49081 ggtagttacg gcgggccgct ttggaggtgg ctcaacgatt acacagcaac tggctaaaaa
    49141 tgcttatctc tcacaagatc agacaattaa acgaaaggcc cgagagtttt ttttggcgtt
    49201 agagttgacc aaaaaataca gtaaaaaaga tattcttact atgtacctta acaactccta
    49261 ctttggaaat ggagtttggg gagttgaaga tgccagtcaa aaatattttg gaaccacagc
    49321 tgctaactta acactggatg aagctgccac attagcaggt atgctcaaag gacctgaaat
    49381 atataaccct taccattctc taaaaaatgc tactcaccgt agagatactg ttttaggagc
    49441 gatggttgat gccaaaaaga ttacccaaac aaaagctcaa caagctagag cagtagggct
    49501 aaaaaatcgc ttagctgata cttatgttgg taagacagat gactacaaat acccatccta
    49561 ctttgatgct gttattagtg aagcaatagc aacttatggt ctttcagaaa aagacattgt
    49621 taataatgga tacaaagttt acaccgagct agatcaaaat taccaaactg gcatgcagac
    49681 gacttttaac aacgatgaac tatttcctgt ttcagcttat gacggtagct ctgctcaagc
    49741 agctagtgtt gctttagatc ctaaaacagg aggtgttaga ggtctgattg gtcgtgtgaa
    49801 tagtagtgaa aatccgactt tcagaagttt taactatgcg actcaagcaa aacgtagtcc
    49861 cgcatcaaca atcaaaccac tcgtggttta cgcgccagcc gttgcttcag gatggtcaat
    49921 tgaaaaagaa ctaccaaata ccgttcaaga ttttgatggc tatcagccac ataattatgg
    49981 aaattatgaa tcagaagatg ttcctatgta tcaagcatta gcaaactctt ataatattcc
    50041 agcagtttct acattgaacg atatcggaat cgataaagcc tttacctatg gtaaaacatt
    50101 tgggttagat atgagctctg ccaaaaaaga gttgggggta gctttaggtg gcagcgtgac
    50161 aaccaatcca ttggagatgg ctcaggcata tgctgccttt gccaataatg gagtaatcca
    50221 tcctgcgcac ttgattaacc ggattgaaaa tgccaggggt gaagtgctta aaacctttac
    50281 tgataaggct aaacgtgttg tcagccagtc tgttgcagat aagatgacag ccatgatgct
    50341 aggtaccttt tcaaatggaa cagcagtcaa tgctaacgta tatggctata cactagctgg
    50401 taaaacagga acgacagaaa ccaacttcaa tcccgactta gcaggcgatc agtgggttat
    50461 tggttatacg ccagatgttg ttattagtca atgggtagga tttaatcaga ccgatgaaaa
    50521 tcattatcta acggattcaa gtgcaggcac ggcttcagct atttttagca ctcaggcatc
    50581 ttacattttg ccttatacca agggcagcca atttcatgta gataatgcct acgctcaaaa
    50641 tggtatttca gctgtttatg gagtcaatga aacaggtaat caatcaggag ttgacactca
    50701 atctattatt gatggtttaa gaaaatcagc acaagaagct tcgcaatcac tatcaaaagc
    50761 agtcgatcag tcagggttac gtgataaagc ccaatctatt tggaaagaga ttgttgacta
    50821 ttttagatag cttgcagtat tttagagatc gtgttaaaat aatagttacg gaggcgttat
    50881 ggcacagaaa aaagcgagtc tagcgtgtgt cgaatgtggc agtcgtaact actctatcgg
    50941 agtgagtagc acgcctaaac caacacgtct agaagtaaat aaattttgca aatactgcaa
    51001 aacatatacc ttacacaaag aaacacgtta aaaaggagag cctgatggga ttcattagcg
    51061 ggacttttaa agtcttaaaa gacacaacat ggccaaatcg taaacaacgt tggaaagatt
    51121 ttatctcagt tcttgagtac acagctttct ttacggtgat tatctacatc tttgaccagc
    51181 tcttagcaaa gagtgtatta gcactgatta atttatttta ggtcaagatt ggtagaaatg
    51241 ataagcttgc ttggaaaagc ctaggctggg agtattccca gccttttttg tagtatcaat
    51301 aatctaatta gtaagctttt ttaaagccca tactggtttg agctattcaa aagcataaag
    51361 gtaaaggcaa tgtagcaacg atctccaaac caagttcact aaattagctt gtaacagagt
    51421 caacgcataa acagcctggc ctcacttgct tagcacatta aaaatagcaa tgaatattat
    51481 ggttgaggaa aacagcctga tagtctgcta aatcttcggg atgataagcc ttgacctcag
    51541 ccatctcata ctccctacct agaagtttgt acttgttttc tccaaattga tggaaaggta
    51601 acagttgcac ttggtcaatc tcaagctgat taaagagctc tgagaaggct ttagcatcgt
    51661 ctagtgaatc attaaattgg ggaataacag ggatgcgcaa gacgatttct tttccagctt
    51721 gaaaggcata atgaatattt ttgataatca agtcattacg aaccccagtc actttttggt
    51781 gtctgagctg attataatgt ttcaaatcgg tatagataaa gtctacgtag tcaataaggg
    51841 tgacaaattg ctcgtgtttg gcaaaggcgg tggtttcaat tgcggtgtga agacctgctg
    51901 ctttggctgc ttttaacagg gctaaggcaa agtcaaattg ggcaaagatt tcaccccctg
    51961 acagggtcat gcccccacct gactcttcgt agaaatcaag gtctttaagg acttcttcga
    52021 tcacctcgtc cacggttttt tcctctccaa ctattttagt attaagccca tcacttgtta
    52081 acatctgctc aggtgctttt tgttgggatt cgggattggc acaccaagga catctcaagg
    52141 gacaaccttt taaaaaaacg gttgtccgaa taccagggcc gtcatgaata ctaaaatgtt
    52201 ggatgttgaa aacaataccg cgatcagtca taagtgtgaa ttcctttcgt tgtaaaacca
    52261 tcataccaga taaacgtaaa taaatcaatt acgaatgaaa gtaaatatct cttttctttt
    52321 aagaaaataa ctggtacaat gaaagggggg tgaatgatga atcgattaga acgtattatt
    52381 caactggttt cccagaagaa aaaaatagat gttaacagtt tatcagagca attagaagtt
    52441 tcgaaagtaa ccattcgaaa agaccttgat aaacttgaaa gtaagggctt gttgcgacgg
    52501 gaacacggct atgcggtgct aaacagtggc gatgacctca atgtacgctt gtcctacaat
    52561 tacaacataa agcgacggat tgcagaaaaa gcagctgaat tggtgcaaga caacgatacc
    52621 attatgattg aatctggctc aacctgtgcc cttttggcag aagtgctttg ccagaccaaa
    52681 cgaaatatta aaatcattac caattcgtgc ttcattgcca actacattcg tcaatatagt
    52741 agctgtcaaa tcattttact gggcggttat taccagccca attcagaggt gactgttggt
    52801 cctttattga aagaaatgat atcccttttt catgtcaatc gtgtctttgt tggaacagac
    52861 ggtttcaaca aagatcttgg ctttatgggc aaggacatga tgcgctcaga aggggtgcgt
    52921 tacatggcag atgctgctga ggaagtggtg attttgaccg attccagcaa gttttcaaaa
    52981 accagtctgg tacaccagtt gtcattagct gatgtcaatc gcgtcattac agaccaagca
    53041 ctagacaagc aaacacaaga gttattaagt tctggtggtc ttgttcttga ttttgtttct
    53101 tagaaaatag gtggctagat gaaagaagaa cgcagacggc tccttgccaa ggtggcttac
    53161 ttgcattatg ttcaaggcaa gagccaaacc ttgatttcaa aggaaatgaa tatctaccga
    53221 acaacggttt gtcggatgtt agcaaaagcc aaggaagaag gcattgttcg gattgaaatt
    53281 gccgactatg atgctgattt atttgcttta gaagaatacg tgcgaaagca gtacggcttg
    53341 gaaaaactag accttgtgcc caaccaggtt gaagataccc caatggatac cttgacaaat
    53401 gttgctaaaa cagcagctga ggtttttaga catgttgtta aagatggcga taagatcggt
    53461 ctgtcctggg gagcgactct ttcttgcttg atggatgagt taaatccaaa agcgatgaaa
    53521 gatgtgttta tttatccttt ggcaggagga cctagccata ttaatgccaa ataccatgtc
    53581 aataccctgg tttaccgctt ggctcgcatc tttcatggta atagcgcttt tatgaacgct
    53641 atggtcattc aagaagacaa acacttggct aagggaatct tacaatctaa atactttaac
    53701 gatattttaa caagctggga ccagttagat cttgccttag taggaattgg tggggagcct
    53761 aatagccttg agcagagtca atggcgtgat ttattaacca gctcagatca tgaccaactc
    53821 aaatatgaaa aagccgttgg tgaagtttgt tgtcgtttct ttgatcaggc aggtcagcca
    53881 gtttacactg gcctacagga tcgaactatt ggtatttcgc tagaacagtt gaggcgtgtc
    53941 cctaaaacaa tggctgttgc aacaggtaaa cacaaggcta aggcaatatt ggcagcctta
    54001 aaagcaggtt ttatcaatta tctagtgacg gataaagaga ccatgctagc tgttttagcg
    54061 ttagatgaag atattgatct taataacgtt cttctttaat agaaattcaa agatactatg
    54121 atatttatag aggcccaaga ccaaacggtc agggcttttt tgtttgatgt gttgataaaa
    54181 cagagattgc tcaaatgtgc atttaatgta ttggcacaaa agtgcattaa acaaaatata
    54241 gcacaaaata tattgaccct aaaaacaaaa atgatacaat aaacttacca acgaaatgta
    54301 aacgattaca aacataataa catcaccttc gaaaaaaaag actcattgtc gatacatcac
    54361 atgaaaaaga aaaaaaggag acaccaatgc aagttattgt accagaccaa atcattatgg
    54421 gcttaatttt aaatgcaggc gatgccaaac aacatatcta ccaagctctg aaatgtgcta
    54481 aagaggacga ttatgccact agtgaaaaag aaatggcctt agcagatgat gccttattag
    54541 aagcccacaa tttacagacc cagtttcttg cccaagaagc tagtggtaat aagtcagaga
    54601 ttacagctct ttttgttcac tcacaggatc acttgatgac gaccattaca gaaattaatc
    54661 tcatcaaaga gattattgac cttcgtaaag aattggcaac taaataagtt ttcatgacta
    54721 aaaaggagat tgacatgatt aaaattggat tgttttgtgc agcaggattt tcaaccggca
    54781 tgttggtgaa caacatgaaa gtagctgctg aaaaaaaagg cattgactgt cagattgaag
    54841 cctatgctca agggaaatta gcggactatg caccattact tgatgtggca cttttaggcc
    54901 cacaggttgc ctatactctg gataaatcag aagctatttg taaagacaat gatatcccta
    54961 ttgcagttat cccaatggct gattatggaa tgttagacgg caacaaggtg cttgatttag
    55021 cccttagcct tgttaaagaa taggagtcaa tcatggcaaa aatgaatatg caaaacatca
    55081 tcaagccaat catgacattt gtgaatatgc gcggcatcat tgccttaaaa gacggtatgt
    55141 tagccatttt acctttgacc gttgtgggga gtcttttcct gattgctggg cagattcctt
    55201 tccaaggggt taatgatgcc attgctagtg tgtttggtgc tgactggaca gaacccttta
    55261 tgcaggttta ccatggaaca tttgctatta tggggttgat ttcctgtttt gcaattggct
    55321 attcttatgc taaaaactca gatgttgaac ctctcccttc aggggttcta tccttgtcag
    55381 ccttctttat tttattgaga tcatcttatg ttccagcaga aggtgaagct attggagatg
    55441 ctatcagtaa ggtttggttt ggtggtcaag ggattattgg tgctattgtg attggtttaa
    55501 cggtcggagc tgtttacaca acatttatcc gtcgtcatat cgtcattaaa atgccagatc
    55561 aagtgccaca agccatcgcc aaacagtttg aagccatgat tccagccttt gtgatcttta
    55621 ccttgtcaat gcttgtgtat attattgcca agtcagtaac aggtggtggc acctttattg
    55681 aaatgattta tgatgtcatt caggtaccgc tgcaagggtt aacgggttct ctttatggcg
    55741 cactaggtat tgccttcttt atttcctttc tttggtggtt tggcgtgcat gggcaatctg
    55801 tggtcaatgg aattgtcact gctcttctct tatcaaatct agatgccaat aaggccttga
    55861 tggcagcagg tgagttatcc ctagacaagg gtgcccatat tgtaacccaa caatttttag
    55921 actctttctt gattctatca ggttctggca ttacctttgg tttagtggta gctatgatct
    55981 ttgcggctaa atccaaacaa tacaaggctt taggtaaggt tgcagccttc ccagccctct
    56041 ttaatgttaa tgaaccagtt gtctttggtt ttccaattgt gatgaatcca gtcatgttct
    56101 tgccatttat cttggttcct gtcttggcag ctctcacagt ttatggcgcc attgctattg
    56161 gtttcatgca gccctttgca ggagtgaccc ttccgtggtc aacaccagcc attatctcag
    56221 ggttcatggt tggtggctgg caaggagcta ttgtgcaaat tcttatactc atcatgtcaa
    56281 cgttggtgta cttcccattc tttaaaatcc aagataatat ggcttatcaa aatgaacaag
    56341 ctagtgaaga gtcatgattt agcgtccaca caaattcttg agaccatctc cagttagagg
    56401 tggtttttta gaaaaagaag aacgatttat caggcctata ttgcacaata gtgcaaaata
    56461 aagtgactat ctcttcttat ggttaaggat acgcaaaagt cgcaatatat gataaaatag
    56521 ttacgaaaga aacatttata atttcgtaag aaagaaggag accccgcatg attgaaacaa
    56581 aaagccctta ttttggacat ttaacagaca gaatggctca ctatcgtgaa gctgtgttag
    56641 acaagaaacc ttatattgat gctgagcgtg ctattttagc cactgaagcc tatcaaaaac
    56701 accaaaataa gccagcaaac ctcaaacgcg cttacatgct tcaaactatt ttggaaaaca
    56761 tgaccatcta tattgaggat gaaagcctca ttgctggtaa ccaagcctct tcgaacaagg
    56821 atgcgccgat tttcccagaa tacactctgg aatttgtcct caacgaactt gatctttttg
    56881 aaaaacgaga tggggatgtc ttctacatta ccgaagaaac caagcaacag ctccgagaca
    56941 ttgccccatt ctgggaaaac aataacttac gtgctcgctg cggggtcttg ctaccagaag
    57001 aagtgcaagt gtacatggaa acaggtttct ttggcatgga aggcaagatg aactctgggg
    57061 atgcccattt agcggttaat taccaaaaac tcttggagca cggcttaaag ggatttgaag
    57121 aacgggcacg agctgccaaa gctgcgcttg atttgaccat tcctgaaaac attgacaaat
    57181 accattttta cgactctgtt tttattgtca ttgatgcagt caaaacttat gccaaacgct
    57241 atgccaagtt ggctagagaa ctagcaaaaa cggctaaacc agaacgtcaa gcagaattgt
    57301 tagacatcgc gcgcatttgt gataaagtgc cttacgaacc agcgaaaacc tttgcagagg
    57361 ctgtgcaatc tgtctggttc attcagtgta ttttgcaaat tgaatcaaat gggcattccc
    57421 tatcttatgg ccgctttgac cagtacatgt atccttatgt caaagctgat ttggaggctg
    57481 gccgtgaaac agaagacaca attgttgagc gtttgaccaa cctctggatt aagaccttga
    57541 ccattaataa agtacggagc caagcccaca ccttctcatc agcagggagt ccactttacc
    57601 aaaacgtgac gatcggcggt caaacacgcg ataaaaaaga tgcggtcaac ccactgtctt
    57661 accttgttct aaggagtgtg gctcaaacca aattgccaca acctaacttg actgttcgtt
    57721 accataaagg cctagacaat acctttatga acgagtgtat cgaggtcatg aaacttggtt
    57781 ttggtatgcc agccatgaac aacgatgaaa tcatcattcc atctttcatc aaaaaaggtg
    57841 tctcagaaga agacgcctat gattactcag ccattggctg tgtggaaaca gcagttcctg
    57901 ggaaatgggg ctaccgttgc acggggatga gttacatcaa cttccctaaa attttgctga
    57961 ttaccatgaa tgacgggatt gacccagcat caggcaagcg ctttgcaaaa ggacacggtc
    58021 acttcaaaga catgacatct tatgaagaat taaaagcagc atgggatgcc accctgcgcg
    58081 aaattacccg catgagcgtc attgttgaaa atgccatcga cctaggtctt gaacgtgaag
    58141 taccagatat tctttgctca gccttgacag atgattgtat cggtcgtggc aagaccttaa
    58201 aagaaggcgg agctgtttac gactatatct caggccttca agtcggtatt gccaacctat
    58261 cagactccct agcagcgctg aaaaaattag tatttgaaga aggtcgatta actccagaag
    58321 aactctggca cgcccttgaa agtgactttg ctggagagcg cggagaagag atccgacaaa
    58381 tgctcatcaa tgacgcacca aaatatggta atgatgatga ctacgcagat agtttagttg
    58441 tcgaagctta cgacacctac attgatgaaa ttgccaaata cccaaatacc cggtatggcc
    58501 gtggcccaat cggaggtatc cgctattctg ggacatcatc aatctcagcc aatgtcggac
    58561 aaggaaaagg aaccttggcg acaccagacg gtcgccatgc aggcacacca ctagcagaag
    58621 gctgttcacc agaacacagc atggacaaaa aaggcccgac ttcagtattg aaatctgttg
    58681 ctaaattacc aacagatgag attgtcggag gagtgctact caaccaaaaa gttaacccac
    58741 aaaccctggc caaagaagaa gacaaactga aattaatggc cttacttcgt accttcttta
    58801 atcgcctaca cggttatcat atccagtaca atgtcgtgtc acgtgaaacc ttgattgatg
    58861 cccaaaaaca tcctgaaaag caccgtgacc tcattgtccg tgttgccggc tactcagctt
    58921 tcttcaatgt gctctcaaaa gcaacccaag atgacattat tgaacgtaca gaacacacac
    58981 tttaggagaa aataagtatg gaatacatgt tagacactct agatttagaa gctattaaaa
    59041 aatggcatca cattttgcct ctcgcaggtg tgacctcaaa cccttctatt gccaaaaaag
    59101 aaggtgacat tgatttcttt gaacggattc gagaagttcg tgccattatc ggtgacaagg
    59161 cttctattca tgttcaagtg atcgcccaag attacgaagg catcttaaaa gatgctgctg
    59221 aaatccgcag gcaatgtgga gatagtgtgt atgtcaaagt acctgtaacc acagaaggcc
    59281 ttgcagccat taaaaccttg aaagccgaag gctatcacat cacagcaacc gctatttata
    59341 cgaccttcca aggactatta gccattgaag ctggtgctga ttatttggct ccttactata
    59401 accgtatgga aaatctcaat attgatccag aagctgtcat aggacaatta gcagaagcta
    59461 ttaaccgcga gaatgctgat agtaagattt tggcagcaag ctttaaaaat gtggctcagg
    59521 tcaataaatc ctttgctctg ggagcacaag ccatcactgc tggcccagat gtgtttgaag
    59581 caggatttgc catgccatct attcaaaaag cggttgacga ttttggcaag gattgggaag
    59641 ccattcatca ccgcaagagc atttaagaaa tagcatcagt agtaatcaca tcattaggaa
    59701 tcacagataa aggagttcaa cgatgaaagt atttgcaagt ccatctcgtt acattcaagg
    59761 taaaaatgcc ttgtttacca atgctaaaac cctaaaacaa ctaggaaata gccccatttt
    59821 actgtgtgat gacgtggtgt atggcatcgt cggagaaaga tttgaaagct atttgataga
    59881 taatggcatg actcctgttc acgtagcctt taatggcgaa gcctcagata atgaaatcag
    59941 ccgcgtggtt gccattgcca aggaaaatgg caatgatgtt attattggac ttggtggtgg
    60001 aaaaaccatt gacagcgcta aggctatcgc tgacttactt gctgttccgg tgattattgc
    60061 cccaaccatt gcttcaacag atgccccaac ctcagcctta tcggttattt ataccgatga
    60121 aggagccttt gaaaaataca ttttctattc aaaaaatcca gatcttgttt tggttgacac
    60181 acaagtaatt tgtcaggcac caaaacgctt attggcgtca gggattgcag atgggttagc
    60241 aacatgggta gaggcgcgtg ctgttatgca aaaaaatgga gacaccatgg caggtggcaa
    60301 tcaaaccttg gcaggagttg ccattgccaa agcctgtgag cagaccttgt ttgcagatgg
    60361 cctaaaagcg atggctagct gtgacagaca agtcgtgacc ccggccttgg aaaatgtcat
    60421 tgaagccaat acacttctta gtgggcttgg ttttgaaagt gcgggtctgg ctgctgcaca
    60481 tgccattcac aatggcttta cagcgctgac aggtgctatt catcacctta cccatggtga
    60541 aaaagtcgcc tatggcacgt tgacccaact tttcttggaa aatcgttcgc gtgaagaaat
    60601 tgaccgctac atcgactttt accaagctat tggcatgcca acaaccctca aagaaatgca
    60661 tttagacacg gctactcaag aggatttctt aaaaattggc cgtcaagcaa ccatggcagg
    60721 cgaaaccatc catcaaatgc catttgttat cagtccagaa gatgtagcag cggctttggt
    60781 tgctgttgat gcctatgtta cgagtcgata ggctaaccaa aaagagattt cttatttgcc
    60841 agataacctc aaaaaaacaa gtctagggag tcatttccta gacttgtttt acttattgtt
    60901 ggttggtaat agcactttta gcagggtcat tgtgggcaat acggctggca gctgcagccg
    60961 caatggcgct aacaatatca tctaaaaagg tatggcagga gttgccatct ttgtggttga
    61021 gtttgtcaac aatccccggt tttgtcttgt ccagataccc ataattggta aaaccgatag
    61081 acccatagag gttaacaatg gataaggcca ggatttcatc aatcccatac agcccttggt
    61141 cggttttcaa gatactaagg agtggctcag acagctggtt ggcttcagcc aatttatcca
    61201 attctacccc agtgataata gcattttgca cttctcgttt tgcaagcacc gcttcaacgc
    61261 tctctaaaca ttctgccatg gtcaaattgg gaatataatc attctgcaaa aaaagcacca
    61321 gctctgcaat agcttctaaa gaaacccctc gttcagccag taattgataa gaaacttctc
    61381 gtaagtgatg gtcagttgac atgtgagacc tccttttttt ctttattgta acataaaaga
    61441 ttttaagaaa cctctacaac agctaaagag gggatagttc ttttttaaga gatgttgact
    61501 actgagaccc cctacttggt aaaagtcaaa gaaacgatag taaagtaacc atcttaccta
    61561 ggcctaaata caatcaccac ccctaggtga cacacagcac ctatttcaaa aatgatatta
    61621 gtatggcaaa acaaaaagac aacgccttct tttttctcct tattatctcg tttaattttc
    61681 atatttttta aaaaaactat tgataaacta gttaagtaag cgtatactat ggttagtgag
    61741 cgaaattaga aaagaggaca agcatatgaa tctacttgga tcaagacggg ttttttctaa
    61801 aaaatgtcgg ctagtgaaat tttcaatggt agctcttgta tcagccacaa tggccgtaac
    61861 aacagtcaca cttgaaaata ctgcactggc acgacaaaca caggtctcaa atgatgttgt
    61921 tctaaatgat ggcgcaagca agtacctaaa cgaagcatta gcttggacat tcaatgacag
    61981 tcctaactat tacaaaactt taggtactag tcagattact ccagcactct ttcctaaagc
    62041 aggagatatt ctctatagca aattagatga gttaggaagg acgcgtactg ctagaggtac
    62101 attgacttat gccaatgttg aaggtagcta cggtgttaga caatctttcg gtaaaaatca
    62161 aaaccccgca ggatggactg gaaaccctaa tcatgtcaaa tataaaattg aatggttaaa
    62221 tggtctatct tatgtcggag atttctggaa tagaagtcat ctcattgcag atagtctcgg
    62281 tggagatgca ctcagagtca atgccgttac aggaacacgt acccaaaatg taggaggtcg
    62341 tgaccaaaaa ggcggcatgc gctataccga acaaagagct caagaatggt tagaagcaaa
    62401 tcgtgatggc tatctttatt atgaagccgc tccaatctac aacgcagacg agttgattcc
    62461 aagagctgtc gtggtatcaa tgcaatcttc tgataatacc atcaacgaga aagtattagt
    62521 ttacaacaca gctaatggct acaccattaa ctaccataac ggtacaccta ctcaaaaata
    62581 ataccaaaag gctagacctc tgctcactag gcctagcttt ttacatcaaa aaaagcaatg
    62641 actatagaaa gtaaaaatac tagaaaaagc aatgattgcc gtcattgctt tttatgattt
    62701 gtcaaaaagt aaaaagcaaa ttgaaaaaat cgccctggag ctgttgagat aaactacacc
    62761 atttattaag ataccaaatc aaaaagctaa caccataaga gcgttagctt tttaaagagc
    62821 ctcaggacag tttatgttta atggcttcta ggtaggtttg aaacatatga tggatcgttt
    62881 tgcaattgag taattggaag atctctaaga tctgcacaca cttttgctca gccccctctt
    62941 taccatttat gaggccaata atgccatcaa aaaaagacac acaacaccgt tcatataagc
    63001 aatcatcatt tagctgataa tcttcaattt ttgccaaaat ctcagaagct ttatcatact
    63061 cttgtcgctg aataaacaaa atcaacatat tgacaaacat ccgaatcgat tcattcccat
    63121 aataccttag ggtattgtat ttatcgaggt tcaaaataac ttttgaaaac accatctcaa
    63181 taaaacaaga ctcaaaaata aacatacaat tattaaaaag cacagtctca tagtgactcc
    63241 aagtttcaat attaataaga tagtttgaca aataagtccg ctctgtcaga cagtcttcct
    63301 cagtaagagt tgctaataac accttgacca aggcaaaaag gttcttttcc tttgttgact
    63361 tactatcttt ataagaatca aggatatgat ttaaaccttc tatgtttcgg cattcaaaat
    63421 aatgttttgc cgtatccata tcaataaatt ctttatattg tttaaagtta ttactaataa
    63481 agagaaactc atcaacattg acattcaagt tgtctaagat ataaagtaac tttttcgaag
    63541 aaatgtcaag attattttta ataaaacgat aataggtttg cctagtgaga taatcaccac
    63601 aaacttgttt aatcgaaatg ttttttgaat gcctaatgaa ttcaacggtt tcaccaattt
    63661 ccatatgtca agccttccta gttgatgtca aaaatacgtt acgcatgtac ctaatacgta
    63721 acaagttgaa tgtttcggat gatagtcgct tatgataggt gcataaggtc aatagccaga
    63781 tgcgatagtt ttatcaactg tcatatgtta aacctttcta atctaataga tgttaaaaat
    63841 acgttacgtg tgtacctaat acgtaacaaa ataatgggtt agcaaaataa gcagctatga
    63901 tatagccata aggttaaaag gaggcgccta ctatgtggtt attgttacta tttttgtagt
    63961 tccttttgca aaatggtagt agataaaaat gagaagtcaa taaaagcatt gacaaacaaa
    64021 agaatcattt tgtttatatt atcagtattt ttaagtttct tgtcaactga aatgagcatc
    64081 tactagccac aatagtaact aaaaggctaa ttgtcagtaa aaatgagata aatcagccag
    64141 gaaaaagcct acgagtcaac taatggacaa ccccaaaaaa gacaaaggac tttcacttgg
    64201 tgttgtggac cctatcacga tccttatcac agaatcagtt attaacaaaa tgagaacggt
    64261 cccatatcat ctaaaaaaac tgtcaagcac aacctattgt ttgctagctg atcttgccta
    64321 tcagtctgcc tagtagatac ggcagaagat aagagatcaa ccaaaagatg ataagtgcaa
    64381 cgactcatag cgtcttttga ccaaaaccaa ttagactcac atgagatgag aataattggg
    64441 ttgggttgtc agtgtcaact aaccgtgtta ttgtctatta ccattcatgg tatcagcgac
    64501 atcgtatgat aaccatgcga ttcagctaag taaggaggtg tgtccaatgt actgttaaaa
    64561 gcaaatgcag tagattaact tattttgaaa gaggtataaa aaaaatgaat aaaaagaaat
    64621 taggtatcag attattaagt cttttagcat taggtggatt tgttcttgct aacccagtat
    64681 ttgccgatca aaactttgct cgtaacgaaa aagaagcaaa agatagcgct atcacattta
    64741 tccaaaaatc agcagctatc aaagcaggtg cacgaagcgc agaagatatt aagcttgaca
    64801 aagttaactt aggtggagaa ctttctggct ctaatatgta tgtttacaat atttctactg
    64861 gaggatttgt tatcgtttca ggagataaac gttctccaga aattctagga tactctacca
    64921 gcggatcatt tgacgctaac ggtaaagaaa acattgcttc cttcatggaa agttatgtcg
    64981 aacaaatcaa agaaaataaa aaattagaca ctacttatgc tggtaccgct gagattaaac
    65041 aaccagttgt taaatctctc cttgattcaa aaggcattca ttacaatcaa ggtaaccctt
    65101 acaacctatt gacacctgtt attgaaaaag taaaaccagg tgaacaatct tttgtaggtc
    65161 aacatgcagc tacaggatgt gttgctactg caactgctca aattatgaaa tatcataatt
    65221 accctaacaa agggttgaaa gactacactt acacactaag ctcaaataac ccatatttca
    65281 accatcctaa gaacttgttt gcagctatct ctactagaca atacaactgg aacaacatcc
    65341 tacctactta tagcggaaga gaatctaacg ttcaaaaaat ggcgatttca gaattgatgg
    65401 ctgatgttgg tatttcagta gacatggatt atggtccatc tagtggttct gcaggtagct
    65461 ctcgtgttca aagagccttg aaagaaaact ttggctacaa ccaatctgtt caccaaatca
    65521 accgtagtga ctttagcaaa caagattggg aatcacaaat tgacaaagaa ttatctcaaa
    65581 accaaccagt atactaccaa ggtgtcggta aagtaggcgg acatgccttt gttatcgatg
    65641 gtgctgacgg acgtaacttc taccatgtta actggggttg gggtggagtc tctgacggct
    65701 tcttccgtct tgacgcacta aacccttcag ctcttggtac tggtggcggc gcaggcggct
    65761 tcaacggtta ccaaagtgct gttgtaggca tcaaacctta gtatggaaat gcatttcgtt
    65821 agaacagaac ctgaggcacg ccgcatagct gaaacctttt gtgccgaaaa cacacaaaca
    65881 aaaaccccta tgcgcgtgca gcagttaagc tatccatcag acacagatca ctcaggtggt
    65941 gagctataca tctatgcttt gtctcctgct ggatttatca tcgtatcagg agacaccaga
    66001 gcgcacacca ttttaggcta ttcttttgat aataacctag acctcaacca tgataatgtc
    66061 aggagtatga tagaagctta ccaaacacaa atcaactctt tggattgatc ggtcaaagta
    66121 gcttttgccc ccctcaccac tcgtttaaga cgaccgtgtt tctaaaatac cactaccttt
    66181 taagtttcac gccggcctaa gcgagtgttt gtctcatgga gcagactgtt tccatcgaaa
    66241 agtcacccat tgataaagga ggtcatcaac gcctactaat gatgacttcc ctaagatgcc
    66301 aaggtaaagg actgagttct gtagagatgg gactcagtcc ttttacgatt tttgggagtt
    66361 attctagcca taccgtggca agaaaacaac acttaaaaat agccaacgtc agtttctgtt
    66421 catacatgac tacagccaaa caccacaacc taacctatcc taaacacagt ggctttctaa
    66481 cgaacagtca caacgagcag caacaccaaa aagcaagatt aagctacgtt taagactaat
    66541 gatataagat aacagtaatt attaatgaga aaagaggctc aggacatgaa acaaatgaat
    66601 aaactcatta caggagtggt aacgctggcg acagtcgtga ccttatcagc ttgtcaatca
    66661 tcacacaaca acaccaaact cgtctcgatg aaaggagaca ccatcactgt cagtgacttc
    66721 tacaatgaga ccaaaaacac agaactcgca caaaaagcca tgttaagctt ggtgattagc
    66781 cgtgtatttg agacacaata tgccaacaaa gtctctgaca aagaggttga aaaagcctat
    66841 aaacaaaccg cagaccaata cggtacatcc tttaagacag tcctagcaca atcaggctta
    66901 acgccagaaa cctataaaaa acaaattcgc ctcacaaaat tagtcgaata tgccgtcaaa
    66961 gaacaagcca aaaacgaaac catctcaaaa aaagactacc gtcaggccta tgacgcttat
    67021 accccaacca tgaccgcaga aatcatgcag tttgaaaaag aagaggatgc caaagcagcc
    67081 cttgaagccg tcaaagctga aggggcagac tttgcagcta ttgccaaaga aaaaaccatt
    67141 gcagccgata aaaaaacaac ctacacgttt gactcaggtg aaacaaccct accagcagaa
    67201 gtagttagag ctgcatcagg cctcaaagaa gggaacagat cagaaatcat cacagcgctt
    67261 gatccagcca cctcaaaacg cacctaccat atcatcaaag tcaccaaaaa agcaactaaa
    67321 aaagcagact ggaaagcgta ccaaaaacgc ttgaaagaca tcatcgtgac tggcaaatta
    67381 aaagaccctg acttccaaaa caaagtcatc gctaaagctc ttgataaagc aaatgtcaaa
    67441 atcaaagaca aagcatttgc caatatctta gcccagtttg caaaacctaa ccaaaaacaa
    67501 cctgcccaaa aatagagggt tgccagttta tttccctaag gttgcttaaa aagacagccc
    67561 taaccatcac tccccttttc aaaacaccga taatggaaac gtgtcctata ctgatggtct
    67621 agggcaatgt cataaagcta aagactctat ccaaataagg atagagtctt taatatttaa
    67681 aaaccagtca gcaaaaaaaa ttcacgctaa gcctagctag aatgaggctt agcgtgaatg
    67741 gtatcagtga tagtccgtta acatagctga ttgggagtca gaaactctaa ctacccaatc
    67801 tgactatacc cccagtacca gaggtgtctc atcgcagaag tagcaatcag ataatcgtct
    67861 gataagctct tgtcctcaag caactgatga atatcgtcgc acgggccatg agctgccggt
    67921 ggctgatagc tagtaggctc atcagccaaa acttttttgg agtaacgctt tggtctcaga
    67981 cggcgccaga gggttgagag aggggtgaga aaaaaacgat gggtcatctt ggcctccttg
    68041 tctaatgata gtcaccttaa cagacaaaag tgtcaataat gtcattttaa ggagaaaaag
    68101 attaaaaatc aaggtcacaa actttccttt gttaaaaaaa cgcgacccta acaaagaatc
    68161 taaatacctc tcgcacttga gcttctcctt gcgcagctat cttgtgcact cagttgcctc
    68221 caagataatg ataacgatac catcattatc ctataggcta tcgcgacaac cccttttttc
    68281 gcctcaacga gtctgacaca gctgtcatga cagaaaaaag acctctgcct atctaagaga
    68341 ccattaattt ttctctcact aaaaaactga ttttagaaac gaagaagcat ggtgtataat
    68401 aaggttcaga acaattatga cataataatg aaagtaaggt taacgaaaca ttgacaaatt
    68461 gtaagtataa acttagaaag ttatctgtag ggctcgtctc cgtcggaacg atgctgatag
    68521 ccccgacagt tttaggacag gaggttagtg ctagtagtag tacggagagc agtaccacta
    68581 cagctaatac tggtaccggt acggcaagtg ggatgactgc cactactcct agtgctacga
    68641 cagatactgg tgaagcagct gggagcggag ctaggagtga agctaatggt gcatcgtccg
    68701 tagtatctag cgaagaaagt cagagttcag gcactactcc agcctcaccc caagcacaga
    68761 cagctccagc agcaacgtca acatcatcgg cttcttctag taatgagaaa actcccaaga
    68821 cagcaactac aactacatca tcgactccag tagcaagtac cagtaataat agcaacaaag
    68881 taactagtac tgaagctgaa acacagacga tggacgtgga acggtataca gttgataagg
    68941 aaaattcaaa gctaaatatt aaagacggta agactccaaa aactaggagt agtgttaata
    69001 aagacacaaa acttattaga aaccgcgatg acaaacagcg tgatatcgtt gatgttactc
    69061 ggacagttaa aactaacgaa gatggcacta ttgatgttac cgtaacggtt aaaccgaagc
    69121 aaattgacga aggcgccgat gttatggccc ttctagatgt ctctcaaaag atgacaaaag
    69181 agaattttga taaggctaaa gaacaaataa aaaaaatggt tacgacttta acaggcgagc
    69241 caactgatgg taaggaaaat cataataggc gtaattctgt acgtctaatg actttttacc
    69301 gtaaggttaa tgagcctatc gaattgactg ctgaaaatgt agacaaaaca ttagatgaag
    69361 tttggaaaaa agctaaagaa gattgggact ggggcgttga cttacaggga gctatccata
    69421 aagctcgaga gatttttaat aaggaaaaag aaaaaaaatc gggtaaacgc cagcatatcg
    69481 tcttgttctc tcaaggcgaa tcaaccttta gttatgatat taaaaataaa agtgatatta
    69541 caaaaacaaa aataactgaa aaagttacga cctctagccc actgtttcct tggctcccta
    69601 tctttaatca cactaaccga aaggcagaga ttattggtga tttagaaaaa gtactagaca
    69661 tggccgaaaa agtgggaata agtttaccta gtagtctgaa gtcagcagtg aaagcccttg
    69721 gcttaactaa tagtgcaata ggttctattt tagggaaagg tttgacagag taccttggtt
    69781 tgacagaata tagttcagat aacttagatg gaggagggtt tgattatagt aaacgtgtag
    69841 gggaaggtta ctactaccac agtttttcag ataggaaata tgaaaataca atgccccttg
    69901 aagaagctat caggacggcc ttagcatcta attttcccaa actcacagat aattggtttt
    69961 tcgatatctt aaatagtttt gtcaataaag atacagttga gaaagctaaa ttagacgtaa
    70021 ttatgaaggt acttaatagt attttttaca aacgtgaata tcgctattac aaccataacc
    70081 tgtcagcaat agccgaagct aaaatggctc aacaagaggg cattaccttc tattccgttg
    70141 atgttactga tttaaactca gcttctaaaa gagtgaggcg acaagcagca gtgcgtaagg
    70201 gcactaagga agaagaaaac aaaaaaaatg aagaagagcg taatacaaag tttgacacct
    70261 atctgaaaaa gatgtctgaa ggtaataatt tcttaagtaa tgttgaagag agagataagt
    70321 tcaaagatac tttaacagag ctgacaatta aagacgaatt tacggataaa gttacggtcg
    70381 agaaggattc ctggagtaaa tctataactg atggacttaa aaattcaaat aacaataatg
    70441 ttaaacatca acaggcaaac acatcgacat ggagtttctt cagttcatcc aaagaaagcc
    70501 tcacctggat tatttccaaa gagcagctca aagaagcctt tgagaaaaat ggttctctca
    70561 cttttaaata caaattacgg gtcaataaag acaaactatt agataaagat aagaagagaa
    70621 caaaacgtga tacacctacg gaaaataaga cttctgtaac ggcagatatc atttcaaata
    70681 ctgttgacta caaaattaat aatcaagaag ttaagggtaa caaacttgat gctgtcaagt
    70741 tgacttatac taaagagacc gttcctgttc cagatgtgga aggagaagtt gtaccaatac
    70801 cagaaaaacc actggtagaa ccaatgacgc ctctataccc tgcaattcct aattacccta
    70861 cccctcaact tccaaaagat gaagatctgg agattagtgg aggtcatgga ccgattgtcg
    70921 atatcgtcga agatactggt acaggtgttg agggcggcgc tcaaaatggt gtggtttcaa
    70981 ctcaggaaaa taaagatcca atcgttgaca tcaccgaaga tacccaacca ggtatgtcag
    71041 gctcaaatga cgcgacagtt gtcgaggaag acacagcacc taaacgtcca gatgtccttg
    71101 ttggtggtca aagtgatcca atcgatatca ccgaagatac ccaaccaagt gtgtcaggct
    71161 caaatgacgc gacagttgtc gaggaagaca cagtacctaa acgtccagat atccttgttg
    71221 gcggtcaaag tgatccaatc gatatcaccg aagataccca accaggcatg tcaggttcta
    71281 atgacgctac tgttatcgaa gaagatacga aaccaaaacg cttcttccac tttgataacg
    71341 agccacaagc accagaaaaa cctaaagagc aaccatctct cagcttacca caagctccag
    71401 tctataaggc agctcatcac ttgcctgcat ctggagacaa acgtgaagca tcctttacaa
    71461 ttgttgctct aacaattatt ggagctgcag gtttgctcag caaaaaacgt cgcgacaccg
    71521 aagaaaacta accctcgtta gtctagcgac cctaagcctt tggctttaag aatttctcat
    71581 tatccccctc aaacaccggt acctcactga gatggcgctt taaaaaggcg ctaatctcaa
    71641 atcaggtatc ccctacggtt gagggggatt aatgggtatc acaacaagaa aaaaggtata
    71701 atgatgaaat atgactaaaa aatttattaa atcagcagtg attctaggct tagcaagcat
    71761 aaccatcagc atgacgcaac ccgttgaagc catttcaaat agcttagaat atcaagcaca
    71821 atacgaacgt gtcaaagaag aactagacgc attaaaagaa aagggcccaa aattaggaga
    71881 acgttccctt tattttagat tggtgaataa atttctaagt tggtttggcc aagtctggga
    71941 cccactcgca atcaaagaaa ccgattacct gttggacctc atcggacaag tcaattactt
    72001 ggtgagtaac accgagtttc aagcccctga gtacaaagat gctaaaaaca aactagactt
    72061 agctgtagca ggctatgacc tctacctagc tagagagaaa aaacgtggtg atgctcctga
    72121 ttaccaagtg acccagctaa cgctagaaca gctcaaaacc atcaaaaaga agatacgaga
    72181 ggccctcgaa acatttgcac aagaggtcaa aacaatccag caaaaaaacc cagacctatt
    72241 tccccatgct tatgttttaa acgctaagag caaagatatc acagataaag cgcaaccctt
    72301 tttagtaaat agttactacg atgtctttta taagcagttt ttattcacta atacaaatga
    72361 cgggtacaac tataataaag aagcagacaa tctgacctcg tatcaaaatc tgattaaaga
    72421 gctattaggc ttaaaagctg agatcgatca gttaacaaaa ggcaagactg gcgatgaccg
    72481 tttagagatg ttaatgtggc aatcaaagtt caccttatct gattcacgga aaaaatcaca
    72541 ccttagcgcc tactatacac aaggcgagta tgtcgataag gtggtcctat ctgaagaagc
    72601 tcccaacttg agaacagcaa aagaaaaggt caagacctta aaagggatct tgcatgatta
    72661 ctatgttgaa actaataagc cagaaaaagc taaaaagtat catgtcgagg acgagacctt
    72721 gccgtctcaa cctgaggctc ctgctacacc tgaagctcct gctcctgctc ctgttcctgt
    72781 tcctggtcaa aaaccagcag aagatgagag atcgccacaa gctacggagc cagctaaccc
    72841 gtcaaaagag gattcctcaa cggacgcatc tcagggatct cacgatagtg aaaacccagc
    72901 gacagacagt ccttctcaac ctcaggcacc agaccaaggc aatcaccaaa gtcaagtgcc
    72961 taacgccaag cctcaaacgg acaagacgga cactcctaac gccccagcca tcccacagga
    73021 caccccaaaa gcgcctgagg ctggtggtca gagtggcccc gctgggaaca ctgaggagaa
    73081 agctcctgac tctggaccta aagagtctga tcaaagctca tctaaagagt ccccatccgt
    73141 tggcgaagac acgaccccta atcagccaga tgtccttgta ggtggtcaaa gtgagccaat
    73201 tgatatcacc gaagacacaa tcactgacgc tcctccgaca gtatctgggc acaacgcatc
    73261 aacacagccc caatctgtgg tcgaagacac agcacctcag cgcccagatg tccttgtagg
    73321 tggtcaaagc gagccaatcg atatcaccca agatacccaa ccgggcatgt caggctctaa
    73381 tgacgctacc gttatcaatg aagatacaaa accaaaacgc gtcttccact ttgacaacaa
    73441 agagccacaa gcatcagaaa aagcggcaga gcaaaaactt gctcctcatg atagccacac
    73501 aacccctcaa gcttcagatg atacagcagc ccctcacttg cctgcatctg gagataaacc
    73561 tgaaaaagtg tttgcacttg ctgccttgac aatggtcgca gctgcagggc tactcagcaa
    73621 aaaacgtcgc aacaccgaca aaaactagtc gctgttaggc acaacgcatc actaaggcca
    73681 gtgcatttgc actggcctta gttgggtttt tatcaaatag agggtttttc atgacaattg
    73741 ttagcacttc ggtgtaaaat aaaagtaata accagcaaag gagcaaccta tgacaaagca
    73801 agatcagtta atcgttgaaa aaatggaaca aacctatgag gcctttagcc caaagctagc
    73861 aaatctcata gaagccctag atgcctttaa agagcactat gaggaatatg ccacacttag
    73921 aaatttttac agtagtgacg aatggtttcg gcttgcaaac caaccttggg atgatatccc
    73981 gtgcggtgtc ctatctgaag acctcctctt tgatatgatc ggtgaccata accaactact
    74041 agctgatgtc ttagacttgg cccctatcat gtacaagcat atgtaaccat tgttaacgtc
    74101 acagatacta cgatgacagg acaaaaaaag cttgaaaatc tcaaaaaaaa acagataaaa
    74161 aacagataat cgttagaaaa acagtagatg cgtctgttaa actaaaggta tcaaaacaaa
    74221 aggagcattt catcatgaaa ttcaaaaaag tattagtcat tcctgcatta gcattagcag
    74281 caacatgctt tttaacagct tgtggcacaa aaaaagattc taaaaaagaa gaagttaaag
    74341 aaatcaaaat gtctgacatc aaagacgacg cagttagcaa aaaaacaaaa gtggttgatg
    74401 gcgaagaagt tacagaatac accacaaaag atggaaacgt gattcagatt cctgcaggaa
    74461 acgaagaagg catggaatca aaagatgctg gtggatcagg cgctcctgct aaaaactaag
    74521 ggttacaaca aagagcataa ggtgactcgc aaacgttacg catgacatga ggcagtctgc
    74581 ctaagatggt aactcactta tcataatgcc taaatagcca aacacactaa ctcgcaaatg
    74641 tacaaaatca tatacccgtg cttatgtgag cgaacggtta tatgattttt gttttccaaa
    74701 aacaagaaaa gaacgctaaa atagccagtt tgtcgtgttt caagctacca aaaaggaagt
    74761 gctaagaagt gctaaaatga aaaaaagatc cattatacct gtcatcttac tgttggtcat
    74821 cggattaatc gttggtgtta agcgtcatca tgactagtag gtcttgctag tgaccgttca
    74881 aaagggataa cgttggtatg gtataaccat aaaaatcgta taaaaagaaa aaatagctat
    74941 tgaggagaaa gtatgtttca gttaagaaaa aaaatgacgc gcaaacaatt agccttgttg
    75001 agtgctggag tgttgacctg tgtggttggt ggtagctact tgataatgaa ccatcaacaa
    75061 caagaaattg tctctagtgt caacaaagta aaagccttaa ccataaaaga agccatggaa
    75121 caaggaaaag atatcagctt gaccttagct ggcgaagtaa cagctaacaa cagcagcaaa
    75181 gtcaaaatcg actcaagtaa aggagaagtc aaagatgtct ttgtcaaaaa aggcgatgtt
    75241 gtcaaagtag ggcaaccctt gtttagttat gaaacgtcac aacggttaac ggctcaaagt
    75301 tcagaatttg atgttcaaac caaagccaat caactccaag ttgctaaaac caatgcagca
    75361 ttgaagtggg aaacctacaa tcgcaaggtc aatgaaatca ataccctaaa atctcgctac
    75421 aacactgcac cagatgagag cttactagag caaattcgca gcgcagaaga cagtgtatcc
    75481 caagcactaa gcgatgccaa aacagcagat agcgatgtca aaaccgctca aatcgaactc
    75541 gataaagcta atgctactgc cacaacggaa aaaggtaaac tagagtatga cactgttaag
    75601 tcagacactg caggaaccat tgttagccta aatactgatt tgccaaatca atcaaaatcc
    75661 aaaaaagaaa atgaaacttt tatggaaatt atcgacaaat caaaaatgtt agtcaaaggt
    75721 aacatcagtg aatttgaccg tgacaagtta aaaatcggtc aaaaagtcga agtgattgac
    75781 cgcaaagaca actctaaaaa atggactgga aaagtaaccc aagttggcaa cctcaaagca
    75841 gaggaaaaag gccaaggtca aggccaaggt ggcaatgacc aacaagacaa tccaaaccaa
    75901 gcaaaattcc cttatgttat cgaacttgac caatcagaca agcagccact cattggttca
    75961 cacacctatg ttaatgtgct caacaatgtt ccagaagctg gcaagatcgt attgaaagaa
    76021 acctttacaa tggcagaaaa tggaaaaacc tatgtgtgga aagttgataa aaacaaggtc
    76081 aaaaaacaag aaatcaagac taagcccttc tcaaaaggtt atgttgaggt gacaagtggc
    76141 ttgactatgc aagataagat tgctcagccg cttcctggca tgaaagacgg tatggaggta
    76201 ggaagtattg ttaaacctta aagatattcg aaaaagctat catcttggga ctgaagaatt
    76261 tgcgatttta aaaggaatcg atttagaagt taacgagggt gactttttag ccatcatggg
    76321 accatcaggt tcgggaaagt caacattgat gaatatcatt gggtgtttag ataagcctgg
    76381 ctctggctca tatgccattg aaggcagaga cgtgtcatcc ttatctgata atgaacttgc
    76441 tgatttgcgt aatcaaaaaa tcggctttgt ttttcaaaac tttaacctga tgcccaagct
    76501 aacagcttgt caaaatgtcg aattgccctt gacttatatg aatgttccta aaaaagagcg
    76561 tcgcaaacga gcgctagaga tgttaaagct agtaggacta gaagaacgca gtgaatttaa
    76621 accgatggag ctatctggtg ggcaaaaaca gcgtgtagcg attgcaagag ctttagtcac
    76681 taacccgagt tttatccttg gtgatgagcc aacaggtgca ctagacacaa aaaccagcgt
    76741 ccaaatcatg gacctattta aacaattcaa tgataacggc aaaacgatta ttatcatcac
    76801 acacgagcct gaagtagctg ccttatgcaa aaagacggtg atcctaagag atggtaatat
    76861 agaacattcc gatatagagt aaagggggaa aataatggaa gatattattg cagctttaag
    76921 ctctatatta tcacacaaga tgcggtcaat tttgacaatg ctagggatta ttatcggtat
    76981 tggtgccatt atcgcaatct tttcaatcat cgaaggtaat accgaaaata ccaaaagaca
    77041 gttgattggt ggcagcaata acactattaa cattgtgttt aacaaaaaaa gcagtattga
    77101 ccctaaattt ccagacaagt caaatgctaa aaaaccagac tatcttcctt ttatggctga
    77161 agaagagctt agcaaaatac agcaagtcaa aggtgtcaaa aacgccctga tctcatatgg
    77221 tattgatgac aaagtctacc atctaggcca aaaatcatct gcaaagattt ctgccatcac
    77281 aaaaaacgta gctgaagtga ggcgcatgac atttattaaa ggcagtgact tttcagacaa
    77341 agactttatt gaccaaaaac aggtgattta ccttgaaaaa agcttgtatg agtcactatt
    77401 tccaaaagac gatggccttg gaaaatttgt cgaagtgatg ggaaatccct tcagggtcat
    77461 tggggtgttt gaatcaaaag aacaaagtgg cctcacaagt gggactgaga aaattgctta
    77521 tatcccgcta catcagtggt ataatattaa tggtgtagtg gatgcgacac ctgagatcac
    77581 gatccagacc tatcgcgcag atgacctcaa acctgtagca aagcgtgtca gtgatatgct
    77641 caatcaaacg atccctaaat cagattatat gtttggtgtc atgaacctta aagaatttga
    77701 gcgccaacta gacaacctaa acaaatctaa ttttgtgtta ttagctggta ttgctagcat
    77761 ctctcttatt gtaggtggta ttggtgtgat gaacattatg ctagtatcag ttaccgaaag
    77821 aacgagagaa attgggatca aaaaagcgct tggcgctaga cgtaagctta ttttaaaaca
    77881 atttttaatt gaagcggtca ttctaacctt gctaggtggt gtgatagggg ttatttcagg
    77941 gatggtatca ggattgatca tcacaagatc actcgagtat ccctatatcc tatccttgtt
    78001 ctcagttgtc ttgagtttag cgttttgttg tattataggg attgtctttg gactattacc
    78061 agccattaaa gcgtctaagc tagacccaat tgaagcattg cgatttgaat aatcaaccaa
    78121 acaagcataa aagtcaaaag ggatgaccct ttgatgtcat ccttagctgc ttgatacact
    78181 aaacgccaat ctagaaaggg aagttatgtt taaaatatta gtagttgaag atgatgatac
    78241 catcagtcaa gtgatttgtg agtttttaaa agcgaataac tatgatccag attgtgtatt
    78301 tgatggccaa gctgccttag acaagtggca gacaacgtct tatgatctga ttattttaga
    78361 catcatgctc ccttccttaa gtggcttaga agtgctaaaa acaattcgaa agacatcaga
    78421 tgtccctatt attatgctaa cggcattaga tgacgaatac acacagcttg taagcttcaa
    78481 ccatttgatt agtgattatg tgaccaaacc attttcacca ctcattttaa tcaaacgtat
    78541 cgaaaatgta ttacgcgtct ctactccaga tgaaaagcgc caaatcggag acttacttgt
    78601 tgatgagact gaacatagcg tctattggca aggaacattg gtcaaactaa ccaaaaaaga
    78661 atatgacatt attgattatt tagcaaaacg tcaccaaaaa attgtcacca gagaccaatt
    78721 gatggatgac atatggggct attctgaact ggatacgcgt gtccttgaca accacattaa
    78781 gaaccttcgt aaaaaaatga cgggtattcc cctcaagaca attacaggca tgggctattt
    78841 attgggagag cgtgagtgag actaatcaaa aaaacctttt tggtcatcaa tggcttaatt
    78901 attgtagtgg ttacctctat tttgttagtg ctttattttg caatgccaat ttattacacc
    78961 aaagtcaaag acaaagaagt taagcgtgaa tttgaccaaa caagcaagca aatcaaaggc
    79021 aaaacggtaa ccgagattag agatatccta acaaaaaaaa tcaacaaaga taatatttgg
    79081 tacagcttag tagacagtga taaccaactg ctctatcctt ccttgcagct gttagacggc
    79141 gtcagtgaaa gcaaagacag tcaaaatgtt aatatcgtca ccacctttga caactcttat
    79201 tctaatgtta aggtgatgag tcaaaaagta accctacgcg atggaaaaaa aatgacattg
    79261 cttgggcaat cttcacttca acccgtaaca gatgctagca aagttctcct tgacctctac
    79321 ccgtcactat tgatgttttc agtgaccgta gggagtattg tcgcctactt atatagtagg
    79381 acttctagcc ggcgtatcct tagcatgtca caaaccgcca aaaaaatggt caacctagaa
    79441 ccaaacttaa cgtgtaccat tcacggcaaa gatgaaatag caatgttggc tagtgatatt
    79501 aaccgtttgt atgcgagtct ttcaacgagt atcaaatcct tgcaaaaaga gtatgaaaaa
    79561 gcttctgatt cagaaagaga gaaatctgag tttttacgca tgacatcgca cgagctaaag
    79621 acaccaatca ccagtgttat cggaatgatt gatggaatgc tctataatgt tggtgacttt
    79681 gcagatcgtg acaaatattt gcgaaaatgc cgagacgtcc ttgaagggca agcccaactg
    79741 gttcaatcca ttttatcttt atctaagatt gaaaccctag cttctcaaaa tcaagaactg
    79801 ttttcactaa aaagcagcct agaagaagaa atggaagtct ttctcgtctt atcagaacta
    79861 aaacatctca aagtgactat caatctcgaa gaacaattcg tcaaagccaa taaagtatac
    79921 ctactaaagg cgattaaaaa tattattgac aatgcctttc actataccaa atcaggcggc
    79981 caagtgatga ttcaactaaa agacaaccaa ctagtgatta aaaatgaagc agagacatta
    80041 ttgacacaac agcagatgaa acagttattc caaccgtttt atcgaccaga ttatagtcgt
    80101 aacaggaaag acggtggtac aggattgggg ctgtttatca cccaccagat tcttgatcag
    80161 catcatctgg cttatcgctt tgttgttctt gatcaaagat ggatggtatt tacgattgat
    80221 tttccatccc atcatgacga ttgatccaca ctagtaggac gacaaaagtc atcaatcact
    80281 aaccaagcct tgacctttac ccatcattgt ttaggcaagt ataaaaaaga ggagagaaat
    80341 catatatgaa gaaaaggaaa ttgttagcag taacactatt aagtaccata ctcttaaaca
    80401 gtgcagtgcc attagttgtt gctgacacct ccttgcgtaa taacacatca tccactgatc
    80461 agcctactac agcagatact gatacggatg acgagagtga aacagcaaaa aaagacaaaa
    80521 aaagcaagga aacagcgtcg cagcacgaca cccaaaaaga ccataagtca tcacacactc
    80581 acctaacccc cccttcaaat gatactaagc agaccgatca ggcatcatct gaagctactg
    80641 acaaaccaaa taaagacaaa aacgacacca agcaaccaga cagcagtgat caatccaccc
    80701 catctcccaa agaccagtcg tctcaaaaag agtcacaaaa caaagatggc cgacctaccc
    80761 catcacctga tcagcaaaaa gatcagacac ctgataaaac accagaaaaa tcagctgata
    80821 aaacccctga aaaaggacca gaaaaagcaa ctgataaaac accagaacca aatcgtgacg
    80881 ctccaaaacc catccaacct cctttagcag cagctcctgt ctttgcaccg tggagagaaa
    80941 gtgacaaaga cctgagcaag ctaaaaccaa gcagtcgctc atcagcggct tacgtgagac
    81001 actggacagg tgactctgcc tacactcaca acctgttgtc acgccgttat gggattactg
    81061 ctgaacagct agatggtttt ttgaacagtc taggtattca ctatgataaa gaacgcttaa
    81121 acgggaagcg tttattagaa tgggaaaaac taacaggact agacgttcga gctatcgtag
    81181 ctattgcaat ggcagaaagc tcactaggta ctcagggagt tgctaaagaa aaaggagcca
    81241 atatgtttgg ttatggcgcc tttgacttca acccaaacaa tgccaaaaaa tacagcgatg
    81301 aggttgctat tcgtcatatg gtagaagaca ccatcattgc caacaaaaac caaacctttg
    81361 aaagacaaga cctcaaagca aaaaaatggt cactaggcca attggacacc ttgattgatg
    81421 gtggggttta ctttacagat acaagtggca gtgggcaaag acgagcagat atcatgatca
    81481 aactcgacca atggatagat gatcatggaa gcacacctga gattccagaa catctcaaga
    81541 taacttccgg gacacaattt agcgaagtgc ctgtaggtta taaaagaagt cagccacaaa
    81601 acgttttgac ctacaagtca gagacctaca gctttggcca atgcacttgg tacgcctata
    81661 atcgtgtcaa agagttaggt tatcaagtcg acaggtacat gggtaacggt ggcgactggc
    81721 agcgcaaacc aggctttgtg accacccata aacctaaagt gggctatgtc gtctcatttg
    81781 caccaggcca agcaggagca gatgcaacct atggtcacgt tgctgttgta gagcaaatca
    81841 aagaagatgg ttctatctta atttcagagt caaatgttat gggactaggc accatttcct
    81901 atcggacgtt cacagctgag caggctcgtt tgttgaccta tgtcgtaggg gacaaactcc
    81961 caagaccata accccacaac caagaagcta cctgcctgtt gaccaatctc aaaaagagac
    82021 agtgtcaact tagaatgagg ttcatcagat gataaagaaa gtgaccaccc cgagtcaaaa
    82081 aataaaaaaa cgtgttcgta atggctatct cctaaaacta ggtacagcct gtttactctt
    82141 aagtatactc agttatggca ttggtctttt gggccagcct agcatggaaa atacgtttat
    82201 gggaatagcg agtgttgcca tgttaggaag tgtctgtttc tttattatct ttgctctaaa
    82261 ccgtatcttt gacgcactag aggacaattt gcgagattag agtaataggt caaataatct
    82321 tccaataatt tagagcacaa gctaagttat tggaagtttt tttgtctttt gagagccatg
    82381 atgccatcaa aaagtcaaac actccttatg atgtgagagt cacatgacta aaattaaaag
    82441 caaaatagac cccaaagccc tgttttctca aaacagccaa cgaaaaaaga caagttaacc
    82501 agttcataaa aaacatcgta gaaacgtttt caagagctaa tgttggagta aattgactga
    82561 agtatgatag aatttttaat gaatg
//
LOCUS       DATWEK010000005        75598 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.005, whole genome shotgun sequence.
ACCESSION   DATWEK010000005 DATWEK010000000
VERSION     DATWEK010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 75598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75598
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.005"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..1400)
                     /locus_tag="VCR92_000398"
     CDS             complement(<1..1400)
                     /locus_tag="VCR92_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEP4267493.1"
                     /translation="MITFLDHRDIEYGVISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGLNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTR
                     MYFWNGAEWEEPEVVNDPERWREDLEKQISEAIEKAKKAQEEINQRTDKELEEFRAAL
                     KNLALPEEAIKKITEA"
     gene            complement(1410..2252)
                     /locus_tag="VCR92_000399"
     CDS             complement(1410..2252)
                     /locus_tag="VCR92_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEP4267494.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSNVERLLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNLSFALRTAELP
                     FGETKPKDITLSGGSFAYAGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            complement(2264..6646)
                     /locus_tag="VCR92_000400"
     CDS             complement(2264..6646)
                     /locus_tag="VCR92_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEP4267495.1"
                     /translation="MPGTFDGSIFADVGANTKDYEQAMARIVSTTQNAFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFQKVIIPVASVIDKIRGNLTGFINQTKMQLQNLVDIGKIRSAFAKAATGVDILTQR
                     ASSKLNNLSAIFETVAGKLPRPFGTAFRKIASSVSTLNSSIQSVGGKISNSLGRQVLN
                     PALQSWNNFFSSVSAKASAFANKVSTSLFGRLTSSLANLSSKIGSSLSNGFSRMSSSA
                     ATSLNGISQKFANTSSAGERLKSTVMSIVQAFSLMAVAQKAMHAITGAIDGAVSRVDT
                     MNRFPKTMALFGYSAEQSKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTS
                     LALAFNNAMIGYGATTEGAEQALRQFNQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAF
                     GFGKNGVQDLKSALSDGKITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHT
                     AVVKGVAGMLSAFDEAAKANGMKTIAETLLSLKPAITSVFDTINSLIPNAVAAFARLK
                     QSINIDFSPLGASVKEVFALINTVLRDFAHTGELSGQAFDNLKAKITSLAPKVIALWA
                     VMNPASAISTIMPLLSLFGKVALALGSLGTSVGAFGGIISSGIASASGVVGAFAATLS
                     GLPGVFTTAAGRGLSVLGTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQ
                     IEQLLNTAVTKGPGIIQGLVKGITSKIPVLIASGTQLIAKFANAITVLLPVIIQAGVQ
                     LITSLVQGIGQNATNLISSAIKIIGSFVSSIASALPQLISVGMELLLNVVNGIVQNIP
                     LIIQQAQQIIDSFGNSLQANLPSIISNGIAILVNLVQGITQMLPTVLQIATQVITSFV
                     SGIVQFLPQLLQGGIQIIISLVQGIIQNLPQIAQSAVQIIQFLASGLTQALPQIIAAG
                     IQLVAQLAVALIKGFPQIISAGIQLIMGLGKAMLGAIPNALSGVWEGIKSGFSSMWDQ
                     ITGKSSTSTAKVSADATVMAMNVGMQTTAMANQANTDTTSMLNSISQNTELANINATS
                     NATQMANNVNAQTGTMSLQGLNDSMSLASGISANMSVANINATTQAREMASGVNGATS
                     SMNLDAINHTLSLASGVGANMGAASTGATSQAQAMSSGVSNSLASMQSNSTKAASGLS
                     NSVTSKMSSAATSATSSVNRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTA
                     KQSMANLVSSVTSGMSRATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASS
                     AGTIYAIANSIAANVAATIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLG
                     KAYATAVTDQNWGVNSTVSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVG
                     DKIYTAVKEKESREQSKDSYFVFD"
     gene            complement(6661..6894)
                     /locus_tag="VCR92_000401"
     CDS             complement(6661..6894)
                     /locus_tag="VCR92_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267496.1"
                     /translation="MEGLEYKQLAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            complement(6969..7424)
                     /locus_tag="VCR92_000402"
     CDS             complement(6969..7424)
                     /locus_tag="VCR92_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267497.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDMDATQIQIIEDMIGRMSNAVS"
     gene            complement(7478..8077)
                     /locus_tag="VCR92_000403"
     CDS             complement(7478..8077)
                     /locus_tag="VCR92_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEP4267498.1"
                     /translation="MANTKKGTTIEITTGKPIVGKKIFYFIQSVDAPKKSQALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQIPESTGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            complement(8089..8448)
                     /locus_tag="VCR92_000404"
     CDS             complement(8089..8448)
                     /locus_tag="VCR92_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267499.1"
                     /translation="MDYSLETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKSRMLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            complement(8452..8796)
                     /locus_tag="VCR92_000405"
     CDS             complement(8452..8796)
                     /locus_tag="VCR92_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEP4267500.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYSEQQRLLHYRVVSPALYSIYLELGTRKMEAQSFLDPALRKEWP
                     VLMANIKKMFKR"
     gene            complement(8793..9071)
                     /locus_tag="VCR92_000406"
     CDS             complement(8793..9071)
                     /locus_tag="VCR92_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267501.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKSRLIKGLAHHKNSTVIYV"
     gene            complement(9082..9438)
                     /locus_tag="VCR92_000407"
     CDS             complement(9082..9438)
                     /locus_tag="VCR92_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEP4267502.1"
                     /translation="MGDKQLIDDIKLFIGISKGDGAQDEIITLAIYESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGAVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            complement(9450..10337)
                     /locus_tag="VCR92_000408"
     CDS             complement(9450..10337)
                     /locus_tag="VCR92_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEP4267503.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            complement(10350..10919)
                     /locus_tag="VCR92_000409"
     CDS             complement(10350..10919)
                     /locus_tag="VCR92_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEP4267504.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKHEYERTFTRADISKMMAAE
                     RTKWESEQSAAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLATTAEEVKANIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            complement(11081..11347)
                     /locus_tag="VCR92_000410"
     CDS             complement(11081..11347)
                     /locus_tag="VCR92_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267505.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEAIKNQNKQIMELKSIVQ
                     RNALATNEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRKWGK"
     gene            complement(11352..11540)
                     /locus_tag="VCR92_000411"
     CDS             complement(11352..11540)
                     /locus_tag="VCR92_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267506.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKEG"
     gene            complement(11568..13016)
                     /locus_tag="VCR92_000412"
     CDS             complement(11568..13016)
                     /locus_tag="VCR92_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEP4267507.1"
                     /translation="MLVVKKNQRQKSLNYWQKRQEDILSYLDRTDLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKVASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKRLKQGFVRGEHPRAMARDLAKR
                     FNVANHRAETLIRTDGTMVINNATARRYLNAGLKYYRDLVRLDDRTTEICRTIAKENK
                     RKLLSELKPGINVAPYHFNCRTTIIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNE
                     HKPQLSLLNEYVKNGTPYKVDGHSVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HIKTPDYLVDGAPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEHIYMIDRRGLDISIIKNKDEVLAVLEKEGG"
     gene            complement(12976..14508)
                     /locus_tag="VCR92_000413"
     CDS             complement(12976..14508)
                     /locus_tag="VCR92_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEP4267508.1"
                     /translation="MEEKQFLAGTRFNENANKQFIMLQEDFEAIDYESKLWIDQLKNY
                     ISRFKAEQLERLKELKRYYLGDNNIKYRPAKTDKYAADNRIASDFAKYITVFEQGYML
                     GVPVEYKNENKDLQAAIDLMSVRNNEDYHNVKIKTDLSIYGRAYELLTVEKIDDKKTE
                     VKLYQLPAEQTFVIYDDTYQRNSLMAVHFYDIDYGSGKRKQIIKAYTSDTIYTYEDYN
                     LETKGMRLKDYEGHFFKGVPVNEYANNEERTGAYESVLDNIDAYDLSQSELANFQQDS
                     VNALLVIAGNAYTGADENDYLDDGRLNPNGRLAISIGFKKAQVLILDDNPNPNGVKPQ
                     AYFLKKEYDTAGSEAYKNRLVADILRFTFTPDTQDMKFSGVQSGESMKYKLMASDNYR
                     EKQERLFKKGLMRRLRLAANIWAIKGNEATTYSLVNDTSIVFTPNLPQNNNEIVTAAQ
                     NLYGIVSDQTIFEILNTVTGVDAEAELERLKEEADKKQSLPEPRLVGDASGQEEPTAE
                     KP"
     gene            complement(14524..15801)
                     /locus_tag="VCR92_000414"
     CDS             complement(14524..15801)
                     /locus_tag="VCR92_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEP4267509.1"
                     /translation="MTTKQRPKINIVIKHPSKVFNKHIYDKLYNYSNFTEVHYGGASS
                     GKSHGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKCKI
                     NMSAFRITLPNGAEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDYTQLTLRLRDK
                     KHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELAN
                     RNEAYYKIYALGQFATLDKLIFPKYDKQILNKDKLSYLPSFFGLDYGFINDPSALLHV
                     KIDDANKKLYILEEYVRKNLTNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIP
                     RMIDVTKGPGTVMQGIQYLLQYDWIVDERCVKTIEELENYTWKKDKKTNEYTNEPVDS
                     YNHCIDAIRYAVQDRIYQSADRSKRMKNAKYYF"
     gene            complement(15791..16243)
                     /locus_tag="VCR92_000415"
     CDS             complement(15791..16243)
                     /locus_tag="VCR92_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEP4267510.1"
                     /translation="MLGGDGKLSKLTLKQKRFADEYIISANATAAAIKAGYSKKTARS
                     IGQENLTKPDIKAYIDERLEKLESEKIATQEEVLQYLTSIMRGDQQEKTLISVGEFGQ
                     KIVDIDVGAKDRIKAAELLGKRYRLFTDKVEMDVSSDVTINVGEWDDD"
     gene            complement(16333..16749)
                     /locus_tag="VCR92_000416"
     CDS             complement(16333..16749)
                     /locus_tag="VCR92_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEP4267511.1"
                     /translation="MSRLSNAQLKAFDEWLFDYRFIDNKIALRKLELQTDMNTAVDKN
                     IGGGRTNFVSKVTEDVVARWDSDRELKGLSNFKEAVIATLNLLDEELTDIFNLRWGVG
                     SSNTWEEIAYTRHLSRKSIYRKRERILEIFSKKIGM"
     gene            complement(16882..17154)
                     /locus_tag="VCR92_000417"
     CDS             complement(16882..17154)
                     /locus_tag="VCR92_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267512.1"
                     /translation="MTEEQMIDCLLYELVKKDKAIKKKNIIITALTVMLLIVVSGLGI
                     SLKSYYEPQIYGLRAQLSRTQKQLKRASDDRARQTKRIAELTKNGG"
     gene            complement(17147..17317)
                     /locus_tag="VCR92_000418"
     CDS             complement(17147..17317)
                     /locus_tag="VCR92_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267513.1"
                     /translation="MKKEYVVRIYTGREKNFEAKPQFEEKTFTRKADMLRFWDSCEAT
                     VKEKYTREREND"
     gene            complement(17318..18640)
                     /locus_tag="VCR92_000419"
     CDS             complement(17318..18640)
                     /locus_tag="VCR92_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEP4267514.1"
                     /translation="MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNI
                     FSEDHKILIVAPKKVAEETWPTEIGKWHFDFTYSKVLGDERKRIEALETEADIYLINR
                     ENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRLVGLTGTPAPN
                     SLIDLWPQIYLMDRGDRLETSQTRFKDKYFVPDKRNGPIIYSWALRDGAEAEIYNKIE
                     DICVSMKAKDYLKLPPRTNDVVSVKLSNMKAYKQLEADLVLEFKNKEISAANSAVLAN
                     KLLQMANGAIYDDDKATVAIHDDKLDALENIVEESQGQPILVFYQYQHDLERLKKRFP
                     QAEELTSVDKWNSGKIPILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARL
                     DRQGQTEPVIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV"
     gene            complement(18637..18912)
                     /locus_tag="VCR92_000420"
     CDS             complement(18637..18912)
                     /locus_tag="VCR92_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEP4267515.1"
                     /translation="MRTEKDIENYLKKKTKGLCLKFASPGTIGVPDRIVVMNTGTFFV
                     EVKAPGKKPRPSQVAMHKKIKKAGQHVWVVDSYESVDIALKEMENWV"
     gene            complement(19298..21682)
                     /locus_tag="VCR92_000421"
     CDS             complement(19298..21682)
                     /locus_tag="VCR92_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEP4267516.1"
                     /translation="MKQEKLIVKSSPLQELHIATGNSRTAKTWKNITLTWQELVERLE
                     KPTVTQETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADSPS
                     KDFLDRLDLLADYAYVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPVARYLANQLGM
                     SNFDDTTYQSVRLMFWPSHSRDADFTFKYNDEAFLSVDEVLDTYPDWRDSSFWPESPT
                     HAVKRQREAKKQGDPLSKKGLIGAFCRNYDIRQAIATFLPEVYEEGTTPDRYTYTEGS
                     TANGLVIYDDVFAYSHHGTDPVGDTLVNAYDLVRIHKFGEQDSETKDITPTNKLPSSK
                     AMNAFVSDLPEIKDYLMAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIK
                     EVPIYWDGLEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETVVAIKAQA
                     FSSEVFTESDLNKIVLANGVYDLRDNSFKTKFDPELHARSSHPVVYDPEAACETFEGF
                     LRETVGAENIDFIFEWFGYNFYREYAIQKMLFIYGSGGTGKSTLINILREMIGADNYS
                     AVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLADGATLKMLTGEDTIHADRKNKEPI
                     NFYNYAKLSFAMNELPPMRDFSGGLKRRMMILEMDKVLTQEVKAKYPLDKIMGEVPGI
                     FNRAMEGLRKALSKRDFSISASMGSSVEKWEKGNDVVAMFLEDECELGEDFKVPVRDV
                     YPAYKFYCQDSGYKPLAKNAFNHRLRELNYENKNVKSGGKQAKNWVGFKLKSEF"
     gene            complement(21687..23609)
                     /locus_tag="VCR92_000422"
     CDS             complement(21687..23609)
                     /locus_tag="VCR92_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HEP4267517.1"
                     /translation="MRHLNIDIETYSSNDIKNGVYKYADAEDFEILLFAYSIDGGEVE
                     CLDLTRQSLPEDIKDMLFDDKVRKHAFNAQFERVCLSRYLGLPYYLDPCQWQCTMVLA
                     QELGLPSSLEKCALYLKLAQEKDTSGKNLIRYFSLPCKPSKANGGRTRNLPEHAPEKW
                     QMFIDYCIQDVVVEMAIAEKLESVPVHDREWDYYACDQRINDRGVALDKELVASALYC
                     KDVKMESLSGELKALTGLDNPNSRAQLLPWLKEHGYSVNGLTKADVEQELKTAEGELK
                     RVLELKLQTAMSSLKKYEAMERAMCSDGRVHGLLQFYGASRTGRWAGRVVQVQNLARN
                     YIKDLDDAREYVKKRDIDAVEILYDSLNDTLKQLVRTALVAKDCCTFYVSDFSAIEAR
                     VIAWFAGEQWRLDVFSTHGKIYEASASQMFGIPIEEIDKELRQKGKISELALGYQGGP
                     GALKQMGALNMGVKEEELQGLVDDWRRANKKIVQFWKDVQRAAIKAIKSRAPIKLGKL
                     RFRYRKGFLFITLPSGRNLAYARAKVEPGDYGDKIVYEGQGDKAYFTAQETYGGKLVE
                     NIVQATARDILAEALLRIEAAGYGVVFHVHDEAIIEGSGLTIEEVNDLMAQAPEWAEG
                     LPLNSEGYVTKYYMKD"
     gene            complement(23652..24215)
                     /locus_tag="VCR92_000423"
     CDS             complement(23652..24215)
                     /locus_tag="VCR92_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HEP4267518.1"
                     /translation="MIMTPNTTKVVTGKVRLSYVALLEPKAFEGQEAKYSTVILIPKT
                     DKVTIKKIKDAQKAAYEAAKDNKLKGVKWERVKTTLRDGDEEMDTEEHPEYAGHVFMS
                     VSSKTKPQIIDKYKNPVDSADEVYSGVYARVSLNAYAYNTAGNKGISCGLNNVQIVAK
                     GDYLGGRSSADADFDEWNEEEDEDDIL"
     gene            complement(24224..25381)
                     /locus_tag="VCR92_000424"
     CDS             complement(24224..25381)
                     /locus_tag="VCR92_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HEP4267519.1"
                     /translation="MPVENHALLSASSAHRWLYCPMLPRLEADYPSRDTVYTQEGTSA
                     HELSEIKLMYKSGKITKRKFNTLTKAFKENSDFYNEEMEEMTELYTDIVMEHLNAYEN
                     AEIELEKRVDFSDWVPGGFGTSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYAL
                     GAYASYDMVYDFDRIKMTIIQPRLDSVSSVDIYVEELLYWADNVVLPMAAQADAGIGD
                     WNLSEKVLQWSPVAAKLVPRAQENWELIDKYDYQEPVYLSDEAVAEILDKASAIKKWV
                     ESVEAYALKEALSGKEVPGYKIVEGRSNRVITDKDKAIDILQDNGFDDEIFKPKELLA
                     MGTLEKLIGKTTFADLLAEVIDKPQGKPVLVKNSDKRPALNSLEQAIKDFE"
     gene            complement(25381..25680)
                     /locus_tag="VCR92_000425"
     CDS             complement(25381..25680)
                     /locus_tag="VCR92_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267520.1"
                     /translation="MIEVTFKAESMAGVFDAMREALDMPKTVTKDVVEEKPAPKKKEE
                     SVTLTLADIKKMAKAKVEEGKSKDIKEVLKEMNVAKVGELEEYQFAEFVEKLEAL"
     gene            complement(25768..25971)
                     /locus_tag="VCR92_000426"
     CDS             complement(25768..25971)
                     /locus_tag="VCR92_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267521.1"
                     /translation="MNYLEYALVYLERELEIIDNEVIEVELPGGDWEFVPNPYYEKGL
                     HDSPHYRSQVAKDILDIKGLLGR"
     gene            complement(26115..26501)
                     /locus_tag="VCR92_000427"
     CDS             complement(26115..26501)
                     /locus_tag="VCR92_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267522.1"
                     /translation="MMTTFEKIIKKINRIEGELVKPEAERRDSLPILSAQLGSIKQDL
                     KLMLWIELPTLNDVERYEALYQGNDFKFSETFLERKATRKAFWRRLAKETFKEDQDRR
                     NFVKLAEKEFKGATLSWQEFLWGKKK"
     gene            complement(26498..26701)
                     /locus_tag="VCR92_000428"
     CDS             complement(26498..26701)
                     /locus_tag="VCR92_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267523.1"
                     /translation="MSKWELQKQLLENATDFESTVEALLDLNESGEISDEELLLNLRI
                     SYRKYSEEKLRIIDKLIKLGGAE"
     gene            complement(26694..26864)
                     /locus_tag="VCR92_000429"
     CDS             complement(26694..26864)
                     /locus_tag="VCR92_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267524.1"
                     /translation="MNKLELFLLVTTVALAIVARIQYEVIKKHNSPENKRKIFREVAL
                     ENSKKWSAERYV"
     gene            complement(26866..27177)
                     /locus_tag="VCR92_000430"
     CDS             complement(26866..27177)
                     /locus_tag="VCR92_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEP4267525.1"
                     /translation="MPKAELVYRPAKQSEKAEAGDYEHLCQIWEGLTVGTAKVWATEM
                     RDHPDFKQFVLNPTHKIVFIDYEGFRLFVKWKSRNRYKPKKETLAEMLENIKFEKRVG
                     V"
     gene            complement(27256..27447)
                     /locus_tag="VCR92_000431"
     CDS             complement(27256..27447)
                     /locus_tag="VCR92_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEP4267526.1"
                     /translation="MPDIAVGREKVVTFLKSNNIKKSDLAAAYGLNRQEVTNILSGST
                     RGPKANQFILRVIADYSIE"
     gene            27498..28286
                     /locus_tag="VCR92_000432"
     CDS             27498..28286
                     /locus_tag="VCR92_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000092751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267527.1"
                     /translation="MSRYSDYKYANTILKSIEERPEKYLIIHYSCESFYNLGGKSPRI
                     ASISVRQFNNAQTNNFSIHQYSEILDTPITDDTYETIEKELLTDFFTFVDRNTDKNWI
                     HWNMRDTVFGFHAIEQRFKVLGGTPIIIDDDKKIDLAYLFKKMYGGGYIDNPHIEKLL
                     ELNNLTPHRFLTGKQEADAFSSRQYHELSMSTSSKVNSFSTFLTLAINDDLKTNTPKW
                     KMRGTNLSGLLSTFQETISGKVIIGIINLIVGGIVGAIIAKYIQ"
     gene            complement(28312..28482)
                     /locus_tag="VCR92_000433"
     CDS             complement(28312..28482)
                     /locus_tag="VCR92_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267528.1"
                     /translation="MKKNIVDLQKRKEHFQWVADSLEGKENELYVERDWYDNPTLISK
                     EDAKKEVEQIRQ"
     gene            28778..29128
                     /locus_tag="VCR92_000434"
     CDS             28778..29128
                     /locus_tag="VCR92_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4267529.1"
                     /translation="MFPTFEKIKELCKQRGITLIQLEETLGYSRNTLYKLKTQKPNAE
                     RIAEIADYFNVSTDYLLGRTDNPAIANGTPSQKTIDFKEIAAQSMSYDGKPLTDDDID
                     LIAAVLEQRFKNRD"
     gene            29131..29517
                     /locus_tag="VCR92_000435"
     CDS             29131..29517
                     /locus_tag="VCR92_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEP4267530.1"
                     /translation="MDLSLQEYVKGHGYELLFYDNRGTDKEAFANHDCKVLGIGSYLD
                     DHEKKKAIYHEIGHKEHTNRQYELNRELCELEADRNMIHHLLKEELSYLDNVNEFNYA
                     RFMEKYKLKTIADEKMVIDEYYTLIG"
     gene            29529..29795
                     /locus_tag="VCR92_000436"
     CDS             29529..29795
                     /locus_tag="VCR92_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HEP4267531.1"
                     /translation="MGFLDNVKEASTVSTASGENYEYVVLQVTLKEKLIGTGSGNLTE
                     LENVINKQAKKGYRLHTITTSNGGSKGFGGGDRIQATMVFEKIK"
     gene            29923..31062
                     /locus_tag="VCR92_000437"
     CDS             29923..31062
                     /locus_tag="VCR92_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEP4267532.1"
                     /translation="MWSEKHKSGKVNFVERYKHPYTGKWCRASVLMEKDTPRIRKEAQ
                     KYLDEKISKILTSLTTTDAYLLDVMNEWWEHHQKSLKSTSVRSLDFRIRELRNLIDPE
                     VMIAKITTKYLQSIIDKIPGSYDKRKRARQLLKQTFDYAIALEYVSINPVISTQLAKP
                     VKTIKDFEDVAQKFLEKDELKRLLDEMYRRKGSIKMAYLAEFMSLNGCRIGEALAIQP
                     DNIKNDIIEIHGTLDYTSNGYRNAIKTTPKTNSSWRETLITKREKEIIQDILKINALE
                     KNTNPNYKDMGYIFISRNGVPIQDNALNTSIRAANKRLEKPIQKELTSHIFRHTLVSR
                     LAENKVPLKTIMDRVGHADSKTTQQIYTHVTKSMKNEVVDILNRL"
     gene            complement(31145..32185)
                     /gene="rfbB"
                     /locus_tag="VCR92_000438"
     CDS             complement(31145..32185)
                     /gene="rfbB"
                     /locus_tag="VCR92_000438"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEP4267533.1"
                     /translation="MYKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNRA
                     NIEAILGDRVELVVGDIADAELVDKLAAKTDAIVHYAAESHNDNSLEDPSPFIHTNFI
                     GTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGQGEGPGEKFTAETKYNPSSPYS
                     STKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLYGE
                     GKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILEKMGQPKDAY
                     DHVTDRAGHDLRYAIDSTKLREELGWEPQFTNFSEGLEETIKWYTENETWWKAEKDAV
                     EAKYAKTQEVIK"
     gene            complement(32429..33022)
                     /locus_tag="VCR92_000439"
     CDS             complement(32429..33022)
                     /locus_tag="VCR92_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HEP4267534.1"
                     /translation="MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MLPIGFPERFFEEGKLQNNVSFSRQHVLRGLHAEPWDKYISVADDGKVLGAWVDLREG
                     ETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYAFVNYA
                     DPSLGITWENLAAAEVSEADKNHPLLSDVKPLKPKDL"
     gene            complement(33022..33891)
                     /gene="rfbA"
                     /locus_tag="VCR92_000440"
     CDS             complement(33022..33891)
                     /gene="rfbA"
                     /locus_tag="VCR92_000440"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEP4267535.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDENMNAISIEEK
                     PEVPKSHFAVTGLYFYDNDVVEIAKNIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYISKEDVHELAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(33950..35056)
                     /locus_tag="VCR92_000441"
     CDS             complement(33950..35056)
                     /locus_tag="VCR92_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEP4267536.1"
                     /translation="MKIAIIGAGIVGSTAAYYLQQSGQKEVTIFDHGQGQATKAAAGI
                     ISPWFSKRRNKVWYRMARLGADFYQQLINDLKEDGFATDFYQQNGIYVLKKQEEKLRD
                     LYELALARKVESPIIGELAIKNRKELGDDFKGLIGFDNCLYASGAARVEGAALCETLL
                     KTSGYPVIRQKVTLKQQGSGYEIAGHYFDQVILAAGAWLPDLLMPLGYQVDVRPQKGQ
                     LLDYDVHHIISDNYPVVMPEGEIDLIPFNQGKISVGASHENDKGYDLEPDWQVLEKLE
                     MQALTYLPLLKEATQKSCRVGIRAYTSDYSPFYGQVPGLKNLYTASGLGSSGLTVGPL
                     IGYELAQLLLGHEGLLTPSDYSPEPYLLRSTGKA"
     gene            complement(35096..35884)
                     /locus_tag="VCR92_000442"
     CDS             complement(35096..35884)
                     /locus_tag="VCR92_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEP4267537.1"
                     /translation="MKAKTLIDAYEAFCPLDLSMERDVKGLQMGSLDKDIRKVMITLD
                     IRESTVAEAIKNEVDLIITKHAPIFKPLKDLVSSPQRDILLDLVKHDISVYVSHTNID
                     IVPGGLNDWFCDLLEIKEATYLSETKEGFGIGRIGTVKEQALEELASKVKRVFDLDTV
                     RLIRYDKENPLISKIAICGGSGGEFYQDAVQKGADVYITGDIYYHTAQEMLTEGLFAV
                     DPGHHIEVLFTEKLKEKLQGWKEENGWDVSIISSKASTNPFSHL"
     gene            complement(35874..36560)
                     /locus_tag="VCR92_000443"
     CDS             complement(35874..36560)
                     /locus_tag="VCR92_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEP4267538.1"
                     /translation="MDSQLSNRLAQVAAYVPKGVKLLDVGSDHAYLPIFLVETNQISA
                     AIAGEVVRGPYESALKNVTQSGLAEHIQVRLANGLAAFEEADDVTAITICGMGGRLIT
                     DILEAGKEKLQGIERLVLQPNNREDDLRAWLSVNAFKIVAETIMAENDKYYEIIVAEH
                     GEKALSATELRFGPYLSQEKSVVFKEKWQREMDKLAYALSCIPEEKTQERQLLLTKIQ
                     QIKEVIVHES"
     gene            complement(36632..37288)
                     /gene="nth"
                     /locus_tag="VCR92_000444"
     CDS             complement(36632..37288)
                     /gene="nth"
                     /locus_tag="VCR92_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEP4267539.1"
                     /translation="MRIGKARLAKVLTIIGQMFPEAKGELDWETPFQLLIAVILSAQT
                     TDKAVNKVTPGLWQSYPEIEDLAFAELSDVENALRTIGLYKNKAKNIIKTAQAIRDDF
                     KGQVPKTHKELESLPGVGRKTANVVLAEVYGVPAIAVDTHVARVSKRLNISSPDADVK
                     QIEADLMAKIPKKDWIITHHRLIFFGRYHCLAKKPKCEICPVQSYCKYYQNTYGKSKA
                     "
     gene            complement(37285..37968)
                     /locus_tag="VCR92_000445"
     CDS             complement(37285..37968)
                     /locus_tag="VCR92_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEP4267540.1"
                     /translation="MSFLEHYKSGNLVIPSALLFHYKDLFKSSDDFLVWQFFYLQNTT
                     KRDDLAPSQIAHALGKSVADINKIISSLTSQGLLDMRTIELTGEIEIIFDASPVLAKL
                     DQLFVSQTATEIDKQETPNHFKRLVDEFERELGRFLSPFELEDLEKTLRDDKTDPDLI
                     REALKEAVFNGKTNWKYIQAILRNWRKEGIVNLRQVEERRRVREGEDLSQVTISEDFL
                     SAMNLWSDS"
     gene            complement(38049..38567)
                     /locus_tag="VCR92_000446"
     CDS             complement(38049..38567)
                     /locus_tag="VCR92_000446"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEP4267541.1"
                     /translation="MDLTNYIASIKDYPKAGITFRDISPLMADGKAYSYAIREIAQYA
                     CDKDIDMVVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPRDVVSADYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIELEGLNGRHAIR
                     NYDYKVLMQFPG"
     gene            complement(38717..40927)
                     /gene="recJ"
                     /locus_tag="VCR92_000447"
     CDS             complement(38717..40927)
                     /gene="recJ"
                     /locus_tag="VCR92_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEP4267542.1"
                     /translation="MIKSKYSWKIKDKKPDDGFFKLAKTKGLTQTAAQLIYERGIRTE
                     EALDEFLTADLSQLHDPYLLHDMAKAVPRIRQAIEEGERILIYGDYDADGMTSASIVK
                     ETLDMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEAVSLIITVDNGVAGHEAIRYAQ
                     EQEVDVIVTDHHSLPEELPEAFAIIHPEHPDADYPFKHLAGCGVAFKLATALLESLPT
                     DCLDLVAIGTIADMVSLTGENRVLVKNGLAMLKHTERVGLQELMSLSPIDLEHFNEDA
                     IGFQIAPQLNALGRLDDPNPAIELLTGFDDQEAQAIALMIKKKNEERKALVQDIFDQA
                     MAMVDPQKPVQVLAQAGWHPGVLGIVAGRIMETIGQTVVVLTIDNGFAKGSARSLEAI
                     NIFEALNGKRELFTAFGGHAGAAGMTLPVDNLEALSDFLCQFVIERGLDQTAKNTLTI
                     DERLSLDDLSLDILKSLDKLAPYGMDHQKPVFYVKDIRVSQARTIGQDQSHLKFKVSQ
                     GKASFDVLAFGQGSQLQEFRQATGLELAVTLSVNHWNGNTSLQFMLVDARVDGVQLLD
                     LRTKTAKVPEGIPTIEEDPNARVILINDIPEDFKTWRNQFVHKDFDAIYFKNQMKHPY
                     YLTGFGSREQFAKLYKTIYQFPEFDLRHKLTELSHYLNIEKLLLIKLIQIFEELSFVT
                     IDDGLMTVNPQAQKREISESHIYQDLKELVKFQEIMALASPKEMYDYLVKSNDQ"
     gene            complement(40924..41688)
                     /locus_tag="VCR92_000448"
     CDS             complement(40924..41688)
                     /locus_tag="VCR92_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEP4267543.1"
                     /translation="MAQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQ
                     HIDNKECLELDITNPVAIEKMVAQIYQRYGRIDVLINNAGYGAFKGFEEFSAQEIADM
                     FQVNTLASIHFACLIGQKMAEQGQGHLINIVSMAGLIASAKSSIYSATKFALIGFSNA
                     LRLELADKGVYVTTVNPGPIATKFFDQADPSGHYSESVGTFTLQPNQVAKRLVSIIGK
                     NKRELNLPFSLAVTHQFYTLFPKLSDYLARKVFNYK"
     gene            complement(41688..42617)
                     /locus_tag="VCR92_000449"
     CDS             complement(41688..42617)
                     /locus_tag="VCR92_000449"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEP4267544.1"
                     /translation="MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKTYV
                     LTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFVVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKDYISAPKKGKIITIIGDTR
                     KTSASVKLAKDADVLVHESTYGKGDERIARNHGHSTNMQAAQIAHEAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKMVQDLEEVII"
     gene            complement(42632..43267)
                     /locus_tag="VCR92_000450"
     CDS             complement(42632..43267)
                     /locus_tag="VCR92_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEP4267545.1"
                     /translation="MNNYIDLAKTYGGFTSLDTNYLNHLLASLTDQQKLAFITPPPSV
                     INAYFAEIYQKQSPQAATDYYFNLSKALGLFTDQPSFEEEKPFVRLNLSGKAYGFAYQ
                     NDQEVALVFSEKAEPKKPELFFELTQIFPQYMVYEDKGQLKMQAKQFEQGECEDITPD
                     DTLLSKIYRLANGITMLKGFNVEELWALSQTFSGQKYYDFAQREFMIYITQ"
     gene            complement(43260..44498)
                     /gene="hflX"
                     /locus_tag="VCR92_000451"
     CDS             complement(43260..44498)
                     /gene="hflX"
                     /locus_tag="VCR92_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEP4267546.1"
                     /translation="MIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMA
                     SFSQKRERYDSKTFIGSGKLDEIKAIVEADEIDAVIVNNRLTARQNANLEAVLEVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLTQVEKNRQTIRDRRVGSDTFKIGLIGYTNAGKSTIMNLL
                     TDDSHYEANELFATLDATTKQLYLENQFQATLTDTVGFIQDLPTELVAAFKSTLEESK
                     YVDLLLHVIDASDPNHSEQEKVVLNLLKELDMLNIPRLAIYNKVDIAEQFTATAFPNI
                     RISARSKDSKILLRRLIIDQIRDQFVPFRIKVHQDKAYKLYDLNRVALLDHYTFDQEI
                     EDISGYISPKQQWRLDDFYE"
     gene            complement(44571..45470)
                     /gene="miaA"
                     /locus_tag="VCR92_000452"
     CDS             complement(44571..45470)
                     /gene="miaA"
                     /locus_tag="VCR92_000452"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEP4267547.1"
                     /translation="MTKIKIVVIVGPTAVGKTALGISLAKAFNGEIISGDSQQVYRQL
                     DIGTAKATQEEQEAAVHHLTDIREVTESYSAYDFVQDAQKAISDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGQVDQEAVKAYRNELEQLDDHDLYERLQVNNITIEQVNRRRAIR
                     ALELAQFADELENAETAYEPLIIGLNDDRQVIYDRINQRVDRMLENGLLEEAKWLYEH
                     YPTVQASRGIGYKELFPYFVGEMTLAEASDQLKQNTRRFAKRQLTWFRNRMAVSFTAI
                     TAPDYPQVVHDRVRDFLGQKEKS"
     gene            45598..45774
                     /locus_tag="VCR92_000453"
     CDS             45598..45774
                     /locus_tag="VCR92_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEP4267548.1"
                     /translation="MIMEYQFVKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFI
                     EENRKKAARRRVAR"
     gene            complement(45892..46800)
                     /locus_tag="VCR92_000454"
     CDS             complement(45892..46800)
                     /locus_tag="VCR92_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEP4267549.1"
                     /translation="MKHLKNPPLVMSGLALGTLSFGNLLATYVSIFSYLGILAALFIY
                     GILLVGMVRNLNDTKMQLRQPLIASVFPTFFMTGMLLSSLFLKVTGGCWLGFLTWWLF
                     FLGNLVLIAYYQYRFVFSFSWDNVFPSWSVLFVGIAMAALTAPASRQFLLGQVIFWVC
                     LLLTAVILPFMAKKTYGIGLGQAVMPNISTFCAPLSLLSASYLATFPRPQVGMVIFLL
                     ISSQLLYAFVVVQLPRLLNRPFNPGFSAFTFPFVISATSLKMTLSFLGWQGLGWQVLL
                     LGEVLLATALVTYVYGAYLRFLFQNK"
     gene            complement(46859..47245)
                     /locus_tag="VCR92_000455"
     CDS             complement(46859..47245)
                     /locus_tag="VCR92_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HEP4267550.1"
                     /translation="MLFIAKQTLKSQLIPQDNLLAESRFNEIMDFLTGDFPLVFRPMY
                     NPHRYTISQDNQALEKVKQASYKRMDIAMTHLDGLIGDSGHVYRDQQTIADAYAYAMA
                     LWSQKTPKSYENYPHLAAFMAKMLEM"
     gene            complement(47556..48542)
                     /locus_tag="VCR92_000456"
     CDS             complement(47556..48542)
                     /locus_tag="VCR92_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEP4267551.1"
                     /translation="MSEKIRVLLYYKYVSIENAQEYAAKHLEFCKSIGLKGRILIADE
                     GINGTVSGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLGLE
                     DNNFDSDINPLETTGEYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWMVREGFKDVGQLHGGIATYGKD
                     PEVQGELWDGAMYVFDDRISVPINHVNPTVISKDYFDGTPCERYVNCANPFCNKQIFA
                     SEENETKYVRGCSPECRAHERNRYVQENGLSRQGWAERLEAIGESLPEFVGA"
     gene            48742..49044
                     /locus_tag="VCR92_000457"
     CDS             48742..49044
                     /locus_tag="VCR92_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267552.1"
                     /translation="MTYELCLEYGTYPLSRVYAYWGEDQNPPTFIQEDRLLCHKLETM
                     NHLFHDLFVTIESQFHYVGFNMPEKRAQIRILYQEVATILKSKYKDYPIKIETFLL"
     gene            complement(49407..49478)
                     /locus_tag="VCR92_000458"
     tRNA            complement(49407..49478)
                     /locus_tag="VCR92_000458"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(49443..49445),aa:Arg,seq:ccg)
     gene            complement(49591..50796)
                     /gene="rpsA"
                     /locus_tag="VCR92_000459"
     CDS             complement(49591..50796)
                     /gene="rpsA"
                     /locus_tag="VCR92_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEP4267553.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDRDADINDFVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     VGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVIEEAAKEARAEVFSKISEGAVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLSIDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVVEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLSVGQEVTVKVL
                     EVNAADERVSLSIKALEERPAQAEGDNKEEKRQSRPRRPKRESRRDYELPETQTGFSM
                     ADLFGDIEL"
     gene            complement(50923..50994)
                     /locus_tag="VCR92_000460"
     tRNA            complement(50923..50994)
                     /locus_tag="VCR92_000460"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(50960..50962),aa:Gln,seq:ttg)
     gene            complement(51045..51125)
                     /locus_tag="VCR92_000461"
     tRNA            complement(51045..51125)
                     /locus_tag="VCR92_000461"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(51089..51091),aa:Tyr,seq:gta)
     gene            complement(51186..51416)
                     /locus_tag="VCR92_000462"
     CDS             complement(51186..51416)
                     /locus_tag="VCR92_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEP4267554.1"
                     /translation="MSKKDKKIEIQLIDHKVMVNETKIDGYQLQIGKRVVGEIAELDE
                     KFAVLKNDGVDCFFKTLEQAVENIIENYNLNH"
     gene            complement(51480..52547)
                     /locus_tag="VCR92_000463"
     CDS             complement(51480..52547)
                     /locus_tag="VCR92_000463"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEP4267555.1"
                     /translation="MKKSYNRKKQKRGTMMTIAIDWDNLGFEYHKLPFRYISYYKNGQ
                     WDKGQLTEDATLHISESAPALHYGQQAFEGLKAYRTKDGSIQLFRPDRNAVRLQATAD
                     RLLMPQVSTEQFIDAAKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPAEEYI
                     FTIFAMPVGNYFKGGLAPTNFIVSEAFDRAAPYGTGAAKVGGNYAGSLLPGKAAKSAG
                     FSDVIYLDPATHTKIEEVGAANFFGITANNEFVTPLSPSILPSITKYSLLQLAEERLG
                     MTVIEGDVPINELDKFVEAGACGTAAVISPIGGIQYKDNLHVFYSETEVGPVTRRLYD
                     ELVGIQFGDIEAPEGWIVKVD"
     gene            complement(52625..55084)
                     /gene="parC"
                     /locus_tag="VCR92_000464"
     CDS             complement(52625..55084)
                     /gene="parC"
                     /locus_tag="VCR92_000464"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEP4267556.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVSFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVVYMIDHPKASLEKLMEFLPGPDFPTGGI
                     IQGADEIKKAYETGKGRVVVRSRTEIEELKGGKQQIIVTEIPYEVNKAVLVKKIDDVR
                     VNNKVPGIVEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTDLQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYISHRKDIIIERSKFDKAKAEKRLHIVEGLIRVLSILDEIIALI
                     RSSDNKTDAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQNEENDLRDLITTLS
                     AIIGDEATMYNVMKRELREVKKKFANPRLSELQAESQIIEIDTASLIAEEETFVSVTR
                     GGYLKRTSPRSFNASSLEEVGKRDDDELIFVKQAKTTEHLLLFTTLGNVIYRPIHELT
                     DLRWKDIGEHLSQTISNFATEEEILYADIVTSFDQGLYVAVTQNGFIKRFDRKELSPW
                     RTYKSKSTKYVKLKDDKDRVVTLSPVIMEDLLLVTKNGYALRFSSQEVPIQGLKSAGV
                     KGINLKNDDSLASAFAVTSNSFFVLTQRGSLKRMAVDDIPQTSRANRGLLVLRELKTK
                     PHRVFLAGGVQSDTSAEQFDLFTDIPEEETNQQMLEVISKTGQTYEIALETLSLSERT
                     SNGSFISDTISDQEVLVARTR"
     gene            complement(55175..57124)
                     /gene="parE"
                     /locus_tag="VCR92_000465"
     CDS             complement(55175..57124)
                     /gene="parE"
                     /locus_tag="VCR92_000465"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEP4267557.1"
                     /translation="MTKKEITINNYNDDAIQVLEGLDAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGDDIKVVINKDGSVSVADSGRGMPTGQHAMGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSAWLEVEITRDGSVYRQRFENGGKPVTTLK
                     KVGTAPKSKSGTVVTFMPDDKIFSTIDFKFNTISERLKESAFLLKNVKMSLTDLRGDD
                     PIIEEFHYENGVQDFVEYLNEDKETLTPVIYMEGQDQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTNLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGEVASHLVRKAIKARDARE
                     AARKARDDSRNGKKNKKDKGLLSGKLTPAQSKNAKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLEDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKTEKVSYAWTDGEL
                     EDLRKEFGKGAILQRYKGLGEMNANQLWETTMDPETRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVKFTLEENTVF"
     gene            57259..57900
                     /gene="plsY"
                     /locus_tag="VCR92_000466"
     CDS             57259..57900
                     /gene="plsY"
                     /locus_tag="VCR92_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEP4267558.1"
                     /translation="MKLLLFITIAYLLGSIPTGLWIGQYFYHINLREHGSGNTGTTNT
                     FRILGVKAGTATLAIDMFKGTLSILLPIIFGMTSISSIAIGFFAVLGHTFPIFANFKG
                     GKAVATSAGVLLGFAPLYLFFLASIFVLVLYLFSMISLASVVSAIVGVLSVLTFPAIH
                     FLLPNYDYFLTFIVILLAFIIIIRHKDNISRIKHHTENLIPWGLNLSKQVPKK"
     gene            complement(57958..59226)
                     /locus_tag="VCR92_000467"
     CDS             complement(57958..59226)
                     /locus_tag="VCR92_000467"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEP4267559.1"
                     /translation="MLLIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVI
                     DASGLIVAPGLVDIHVHFREPGQTHKEDIHTGALAAASGGVTTVVMMANTNPVISDVE
                     TLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVL
                     KEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVQVVAFAQQLGAKVTAEVSPQHFSTTEDLLLIVGTSAKMN
                     PPLRTQRDRLAVIEGLKSGVITVIATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLG
                     LTHLVEPGHLTLMSLLEKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFA
                     SKASNSPFIGNKLKGVVKYTIADGEVVYPN"
     gene            complement(59350..60003)
                     /locus_tag="VCR92_000468"
     CDS             complement(59350..60003)
                     /locus_tag="VCR92_000468"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEP4267560.1"
                     /translation="MAHSIWHEKIKSFLPEHYYGRINHFLDEAYASGLVYPPRENVFK
                     ALQVTPLEETKVLILGQDPYHGPKQAQGLSFSVPEEISAPPSLINILKELADDIGPRD
                     HHDLSTWASQGVLLLNACLTVPAGQANGHAGLIWEPFTDAVIKVLNEKDSPVVFILWG
                     AYARKKKAFITNPKHHIIESPHPSPLSSYRGFFGSKPFSRTNAILEKEGMTGIDWLQ"
     gene            complement(60136..60786)
                     /locus_tag="VCR92_000469"
     CDS             complement(60136..60786)
                     /locus_tag="VCR92_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEP4267561.1"
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFLTGLVFGLLLALLGR
                     SHQPLLHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYI
                     SEVFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSS
                     LAAMITVPDIFQNAKIIGGREWDYMSMYILVAFIYWIIAFLLERYQEFLENKLALV"
     gene            complement(60815..61678)
                     /locus_tag="VCR92_000470"
     CDS             complement(60815..61678)
                     /locus_tag="VCR92_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEP4267562.1"
                     /translation="MKKSVTLLSIGLASLLLAACAPHKSQKSSWETIKEKGVLKVATP
                     GTYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLN
                     NFDITPKRQKKYNISTPYKYGVGGMIVRADGSSNMAKKDLSDWKGKKAAGASGTEYMK
                     VAQKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMS
                     DAQYNPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDK
                     KIPIIDTKDVN"
     gene            complement(61796..63250)
                     /locus_tag="VCR92_000471"
     CDS             complement(61796..63250)
                     /locus_tag="VCR92_000471"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEP4267563.1"
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSE
                     RFEAALEEAKQRDFSGKLFAGVPIFLKDLGQELKGDLSTSGSKLFKNHHATKTDLFVK
                     RLEDLGFIILGRSNTPEFGFKNISDSQLHGPVSLPHDNTRNAGGSSGGAAALVSSGIS
                     ALATASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTR
                     NLLYYLQMEQMESPFPLATLTKNSIYQSLQRPLTIAFYQRLSDGSPVSLDTEKALRQA
                     VTWLREQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMET
                     MTWAIYQSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVP
                     DSKLMANLAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEG
                     LPMGIQLIAAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            complement(63447..64076)
                     /locus_tag="VCR92_000472"
     CDS             complement(63447..64076)
                     /locus_tag="VCR92_000472"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEP4267564.1"
                     /translation="MTLGSQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLS
                     YPKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDH
                     GAGNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKAS
                     QNFKEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            complement(64134..64826)
                     /gene="pyrF"
                     /locus_tag="VCR92_000473"
     CDS             complement(64134..64826)
                     /gene="pyrF"
                     /locus_tag="VCR92_000473"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEP4267565.1"
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQG
                     PDIVRSIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAARE
                     GLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEV
                     EAIKAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPV
                     AAYQAIKAEWAG"
     gene            complement(65103..65639)
                     /locus_tag="VCR92_000474"
     CDS             complement(65103..65639)
                     /locus_tag="VCR92_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267566.1"
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEF
                     PAHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLI
                     DLCQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEE
                     EAFIKYYQSPKVPTGEFE"
     gene            65861..66766
                     /locus_tag="VCR92_000475"
     CDS             65861..66766
                     /locus_tag="VCR92_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEP4267567.1"
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMG
                     ITIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFV
                     VNAFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDD
                     NHLTASPLFKAQPHIFVSKSNPLATKSLLNMDDLRDFPYLSYDQGIHNSFYFSEEMMS
                     QMPHSKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFI
                     KHEKANLSKMGERFIEYLLEEVTFD"
     gene            complement(66845..67633)
                     /locus_tag="VCR92_000476"
     CDS             complement(66845..67633)
                     /locus_tag="VCR92_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEP4267568.1"
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERR
                     ELNLAFLAEHAAENRIIGDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRS
                     VSPILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSR
                     NVTTKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSS
                     QAFLENIITLATFSGVIYRREPFYFDDMNAIIKTELGLWRQSIV"
     gene            complement(67626..68339)
                     /gene="deoD"
                     /locus_tag="VCR92_000477"
     CDS             complement(67626..68339)
                     /gene="deoD"
                     /locus_tag="VCR92_000477"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEP4267569.1"
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRN
                     MFGYTGTYKGRRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRE
                     LVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFY
                     TNMPERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEER
                     QTTFTDMMKVALETLIAND"
     gene            complement(68924..69733)
                     /locus_tag="VCR92_000478"
     CDS             complement(68924..69733)
                     /locus_tag="VCR92_000478"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEP4267570.1"
                     /translation="MSLMTKINETKDFLVAKGIEAPEFGLILGSGLGELAEEVENPVV
                     IDYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKA
                     LGCEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTK
                     VYRNKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTEHIKEDFKGLVKAILAEL"
     gene            complement(69717..70157)
                     /gene="arsC"
                     /locus_tag="VCR92_000479"
     CDS             complement(69717..70157)
                     /gene="arsC"
                     /locus_tag="VCR92_000479"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HEP4267571.1"
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETL
                     IELLQSMGISARELLRTNVPEFEAHGLANQAVAEKDVINAMLTDPILINRPIVVTRKG
                     VKLCRPSETLLDILPVPLPSPYIKEDGEIVNPIEVKGEKDVIDD"
     gene            complement(70173..71384)
                     /locus_tag="VCR92_000480"
     CDS             complement(70173..71384)
                     /locus_tag="VCR92_000480"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEP4267572.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLSVPNMAKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGSRQMETGELIV
                     YTSADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRHDYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIIANMKEDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDIA
                     MIGESFLGHLK"
     gene            complement(71461..72144)
                     /gene="rpiA"
                     /locus_tag="VCR92_000481"
     CDS             complement(71461..72144)
                     /gene="rpiA"
                     /locus_tag="VCR92_000481"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEP4267573.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQE
                     GLQVVGVTTSSVTSKQAEVLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMK
                     GDSRLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGV
                     TVLEVPKAS"
     gene            72522..74621
                     /locus_tag="VCR92_000482"
     CDS             72522..74621
                     /locus_tag="VCR92_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEP4267574.1"
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPE
                     EFQHYRQTGQLPVATTKATTSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEI
                     QDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
                     EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKP
                     ALSRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQ
                     HHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEI
                     AKQKERQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTG
                     IPVSNMGTNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLF
                     VGPTGVGKTELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNN
                     TLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATS
                     NAGFGQQDTETSGFNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVN
                     QTTAKKGISLTIADDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKK
                     LQAILEEGQLVIRQKDQ"
     gene            complement(74679..74858)
                     /locus_tag="VCR92_000483"
                     /pseudo
     CDS             complement(74679..74858)
                     /locus_tag="VCR92_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(74905..75105)
                     /locus_tag="VCR92_000484"
     CDS             complement(74905..75105)
                     /locus_tag="VCR92_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEP4267575.1"
                     /translation="MIEVLSKQEILNLLTNNSRYQISKATGISEQTLSNYANGVTDVG
                     RMSYNNAIKLTKYAKENEVKLK"
     gene            complement(75255..75401)
                     /locus_tag="VCR92_000485"
     CDS             complement(75255..75401)
                     /locus_tag="VCR92_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267576.1"
                     /translation="MKTSEIIELISSIGIALTGFGSALTGVAKVIKATKKEPQKTAQP
                     RKFK"
BASE COUNT        21967 a        16372 c        13355 g        23904 t
ORIGIN      
        1 atagcctcgg tgattttttt aatcgcttcc tctggtaacg ctaggttttt gagggcggct
       61 ctaaattctt caagctcttt atcggtgcgt tggttgattt cttcctgtgc ttttttggct
      121 ttttcgatcg cctcagagat ttgtttttcg aggtcttcac gccatcgttc tgggtcgttc
      181 acaacctcag gttcttccca ctcagcacca ttccagaaat acattctagt agtatcgcca
      241 acttttagga ataatatgtc tccttttttt aaggttcctt ttggttcatc tttgggcatt
      301 tctgtgccac cgtaaacagt atttttcccg tcagcagata ctagtgcttg tgttgctact
      361 tcaattgcag aagcaatatc tgcatctatc tgattgattc tactgtttat agacagactt
      421 cctacgcttt gttttttcac agatccgata tcattacaag tgacttcatg ttttactaaa
      481 gctccagttg cgtcgtagta gcttgtaaaa gaaactatcc gtatacgctc ttgaaaacct
      541 aaagtctcat ttatcgccat aatgtagtca ccagcaaccg gcctctcaca tctataccca
      601 gctctcgtta aatcttccat atcaattttt actgatatct tatatgaatt ttcaacatta
      661 ctttttaaag cttcttttag attatctgcc accgtgaagc gctcatccgt cagaggcgcc
      721 ccttcaagtc gaccgtactc cttggcaaga ggactttcgt attccgcctc aagtctcccc
      781 ttagagtggt cctctgggtc ggtccatgca ccaaagcctt tctgataggt aataaagcta
      841 tcaatatttt tttcaatggt aaggtcattc atgttgaaat tttttcgtac cactgttgac
      901 agatcagtac ctatgttttt taatagccga acaactttcc cgctgactga aaattcaagt
      961 ccggtcgctt taataatctc attgaataaa tctaacctgg acttataatt aaaagattgt
     1021 tttctaaatg cgttcaaacc tacttctagc ttatagcggt acccactacc tttaaatact
     1081 gtctctagat aggtatcaat ggtatgagac ccatctccga gaccctcata gatactactc
     1141 ttgctgaagt cccaaaaaaa ttggtgtatg gcatcaaacg aaacttgcgt tttttgacca
     1201 acatcaacag gctttgcgta aataacaacg taatactcat cttcaaatct aagtcgccac
     1261 cctctatcga tattattgag gacatcactg tttgtataaa tttccccgct cactgagcgc
     1321 tcaccattaa cagcattagt atgcctaatg acactaatga ccccatactc aatgtcacga
     1381 tgatccaaaa aagtaatcat tagacctccc tatttataca actctacaaa atttaaaatc
     1441 ctaatcgtgc caagaaaatc cgttttgtaa gtaattctct tgttaggatt aggattgaag
     1501 ataaaatact catagttcgt tttagcattg acataatttc cgtttagtgt ggtagctatg
     1561 cctgtcaaaa gtaatttatc actattttgt agctggctat tctgcttaaa ctcaaagcgc
     1621 ctgccatcaa tttcaatata aaaattagtc tgacctccag aaggagtaag ctctataata
     1681 aaaggccact ctagctgact tgctttagcg gttcctgcat aggcaaaact gccccctgat
     1741 agagttatgt cctttggctt tgtctcaccg aaaggtaatt cagcagttct tagcgcgaag
     1801 gaaagattat attttagtcc ttgactggtt tttcctataa attcataagc gatagtgtcg
     1861 tctaagatga ctttaaatct atatttccaa ggtttatgag gagagccaat aagttgcagg
     1921 tctcctgtgc tttcccctgg aagctcaaag ttaaatagat ctgagttttc agggtacatc
     1981 ttagtcacgt agaaaggttc gtcaacaaca agcagagcgt ttagttcgtc ctgtttgtcc
     2041 aaaagtcttt ctacgttgct taccgtcact cttcctttga ccttaagcgt tttagtcgta
     2101 aaagtagccc catcgtagat gtaaccactc cttcctttga ctgctcggtg tgatacagat
     2161 agtaaaggag cgctatcttc aatagcaata ttataaatac caaagtcaga caacctagtt
     2221 gcctgactct ctttttctat taataaatcc aaaatactcc cttctagtca aaaacaaaat
     2281 aagaatcttt agattgctct cttgattctt tttctttaac agccgtgtaa attttatctc
     2341 caacaatctc attatgcact tcaaagatag gctctgacaa ttgagactgc ctaacctctt
     2401 cgctaagatt atcaagagag gtattgattc cactattatt aactttagca gatgttgaaa
     2461 cagtactatt taccccccag ttttgatcag taactgctgt tgcgtatgct ttacctaggc
     2521 tattgatctc acctatccac tctgccatac cgagggcaaa cccctctcca gtaaatgcac
     2581 ctagtgtttt agtgacacga gatggggagt gaatatctaa agcgcgtcta attgttgctg
     2641 ctacattagc ggcaatgctg ttagctattg cgtagattgt gcctgcgcta ctagctagac
     2701 cattagcaaa accttgacct gcataagctc ctgcagaaga catctgccct gccaaagccc
     2761 tgaatattga gaggatcttc tgacaagcat tattagacac cgcggttgca cgagacatcc
     2821 cagaagtcac tgaacttaca aggtttgcca tagattgctt tgcagtactg ttaatgctac
     2881 taaatcctgt tttaaccgca ttggctatcc cattcattga ggttgttgct gaagtcttcg
     2941 ccttattgaa gccagactcg accgccgagg acaacctatt aacgcttgag gttgcagagg
     3001 ttgctgcaga agacattttg cttgtcacac tattagacag accagaggct gctttagttg
     3061 agtttgactg cattgatgcc aggctgttac tcacccctga gctcatagct tgcgcctgag
     3121 aagttgcacc tgtgctagca gctcccatgt tcgcaccaac accactagct aagctgagcg
     3181 tatgattaat ggcgtctaga ttcattgaag aagtcgcacc attaacccct gaagccattt
     3241 ctcgagcctg agtagtagcg tttatattag cgacagacat attagcgcta atgccactag
     3301 caagagacat cgaatcattc aacccctgaa gactcatcgt tcctgtctga gcattaacgt
     3361 tattagccat ctgtgtggca tttgatgtag cgtttatatt agcaagctct gtattttgac
     3421 taatgctatt aagcatagat gtcgtatctg tattagcttg attagccata gctgtcgttt
     3481 gcatcccaac attcatggcc atgaccgtgg cgtccgcaga gactttagct gtacttgtgg
     3541 aactcttacc tgtgatttgg tcccacatcg aactgaatcc gctcttaata ccttcccaaa
     3601 ctcctgaaag agcgtttggg atagccccta acatggcttt accgagcccc ataattaatt
     3661 gaatacccgc agaaataatc tgtggaaatc cctttatcaa ggctacggct agttgcgcaa
     3721 caagctgaat gcctgctgcg ataatctgag gtagagcttg cgtcagtcca gaagctaaaa
     3781 actgtataat ctgtacagca gattgtgcaa tctggggtag attttgaata atcccctgca
     3841 caaggctaat aatgatttga ataccacctt gaagtaactg cggtaaaaac tgtacaattc
     3901 cagatacaaa actcgtaatg acttgagtag ctatctgcag aacagttggc aacatttgag
     3961 taattccctg tacaagattc accaaaatag ctataccgtt gctaataata ctaggaaggt
     4021 tagcctgtaa actattccca aaactatcaa taatttgctg ggcttgctgg ataataagag
     4081 gtatattttg aactatgccg ttgacaacat ttaataatag ctccattcca acagaaataa
     4141 gctgcggcaa tgcactcgca attgaactaa caaaactacc aatgattttt attgctgaac
     4201 taattaaatt cgttgcattt tgtccaatac cttggacgag actcgtaatt agctgaacgc
     4261 cagcttgaat tataactggt aataacactg tgatagcatt tgcaaattta gcaatcaatt
     4321 gagtgccact agctatcaaa actggtattt tagaagtaat tccttttaca aggccttgaa
     4381 taataccagg accttttgta actgcggtgt taagtagctg ctcgatttgt gcgccaaact
     4441 gactattaat caaaccaagt cctgccacca caagacctag aatagcggcc ggtcctatgg
     4501 ccgccagtgc taaactcaca agactggaca ttgcgcttgt catagttcca agcacagata
     4561 gcccacgccc tgctgcggta gtaaaaacgc caggtaatcc gcttagagtt gccgcaaagg
     4621 caccaacaac gccgctggca ctagctatcc cactagaaat tatgccgcca aacgccccga
     4681 cagaagtccc taagcttcct aaagctagag caacttttcc gaatagagaa agcaaaggca
     4741 ttatcgttga tatagcgcta gcggggttca tcactgccca aagggcaatg actttagggg
     4801 ctaaagaagt gatttttgct tttagattat caaaagcctg ccctgataat tcaccagtat
     4861 gtgcaaaatc tctaagaaca gtattaataa gagcaaacac ctctttaacg ctggcgccta
     4921 atgggctaaa gtcaatattg atagactgtt ttagcctagc gaatgctgca actgcatttg
     4981 gaataagaga attaatcgta tcaaaaacac tggttattgc tggcttcaga ctaagaagtg
     5041 tttcagcaat ggtcttcatg ccattagctt tagccgcttc atcaaaggct gaaagcatac
     5101 ctgctacgcc ttttacgacg gcggtatgta cgttcttcca tgcagttcgg attccaccag
     5161 ccgatgattg ggccatctct gcaaatccgc cttgggcatc gttaagctca atcattttat
     5221 ctgcgaactc ttgtgcagtg attttgccat cagataaggc tgattttaaa tcttgtacgc
     5281 catttttacc aaaaccgaag gcttccgcca ttttagacat taaacctggc gcagcttctg
     5341 atacagagtt aaactcttca gcttgaattt ttccagaccc caacgactgg ttaaactgcc
     5401 tgagtgcttg ctcagcccct tcagttgttg ccccgtaacc aatcattgcg ttattgaagg
     5461 cgagggctaa actagtccct ttatctaaac ttcctgtggt tatggcgagc tgttgagcgc
     5521 tttttacagc actgtctaga ggagttggca gaccttcaat tccttttgat agcttatcaa
     5581 ttgatgcctt agattgttca gcagaatacc caaatagcgc catcgttttc ggaaagcggt
     5641 tcatggtatc aacgcgacta accgccccgt ctattgcccc agtaatagcg tgcatagctt
     5701 tttgagcaac agccattaaa ctaaaggcct gcacgatgct catcactgta cttttgagtc
     5761 tctctccagc agaagaggtg ttggcgaatt tctggctgat tccattcaag gaagtagccg
     5821 cagaactaga cattctgcta aaaccattgc taagactgct ccctatttta cttgataaat
     5881 tagctaaact tgaggtcagc cgaccaaaca aactagtact cactttgttt gcgaaagcag
     5941 acgccttagc tgatacagaa ctaaaaaaat tattccatga ctgtaaggct gggttcaaga
     6001 cttgccgacc aagtgaatta gaaatcttcc ctccaacaga ctgtatagag ctattcaggg
     6061 tagaaacgga tgaggcaatt tttctaaacg ctgttccgaa tggtcgcgga agcttgcctg
     6121 cgaccgtttc gaatattgca gataagttat taagcttact acttgccctc tgagttaaga
     6181 tatcaactcc agtcgcagcc ttggcaaatg cagatcttat cttaccaata tccacaagat
     6241 tctgaagttg catttttgtt tgattaatga acccggttaa gttaccccgt attttgtcaa
     6301 taacacttgc aactggaata atgacttttt gaaaaccatt ctttatgggt tcgggaattt
     6361 tttcgccaat ggaagctgct atgcgttgaa tttcaccaat gctcagtttt aaaccagtag
     6421 cgtaggcaga gccaagtctc ttcccgagcg attcgccgtt gttcgccagt tgggccatga
     6481 tttgtccaat gatttgaacc attttattac tactgttaac cgctgtatct tgggcttttc
     6541 tgaaagcatt ctgagtcgta ctaacaatac gagccatggc ctgctcatag tcctttgtgt
     6601 tggcaccaac atcagcgaaa atagaaccat caaatgttcc tggcatctac tcctccttat
     6661 ctatctattt tgaaaatgat tattaagcat ttgtattctc tcaacaatac tgctatcact
     6721 atcggcttgg ctacggctag ctttttgata cgatcttttg atagttagcc tatgcttatc
     6781 gtatttgagc ttacctacat caaccttttt agcatttaat gtatatctaa gctttagaga
     6841 caattcagag aggttctcgc gctcagcaag ctgcttatac tcaagcccct ccataatagc
     6901 ctctagctcc cacttagtac atttatagat agtatcaatg tctgtgagcc ctagccgtgc
     6961 gcaatttact aagatactgc gttgctcatt cttccaatca tatcttcgat aatttggatt
     7021 tgagttgcgt ccatatcgtc cttcgctttg agataacgag ctgatttctc catgttttcg
     7081 atatatttca aaatcttcgc tctgaaaaaa ccagaatcaa ccatttcttt ttcaatctca
     7141 gcaaacaacc cttctgttgt tccttcttca tcaacagctt ctgcaattgc atctagaatt
     7201 tcatcttcag ttagcgcttt ttttccgctt cccgcagata aacgcacaag gtcaacaatg
     7261 gcgctttcat tacgctctaa gatattgaaa aacaaagcac caacaccatc tgcattgcgc
     7321 tctcctgttt ctgggttaat tgttcctagt ttattattga tcttaaacat agttttaaaa
     7381 tcaaatttaa tatcgatatt tcgttttgct gctgtaaatt ccattatttt atctcctttt
     7441 taaatcaaaa tggggtagca gttgccaccc ctgtgtgcta tttagtgata ttatcgtagt
     7501 cgccagtagt atcacccgga ttttgatagc cgtatacatt ttctagcatt tcaatttctt
     7561 ctttcgtgag agggaattta ccatcttgta aggcccctac aatgttagcg gtgtaggaca
     7621 tttctactaa gtctgaaata ccagtaccgc gttcgatttc gtcaatcttg gcgtacccaa
     7681 acttagcagg gtaaacatct ttcttgggtc cagtcgattc aggaatttga atctgttctt
     7741 tgacactttc gtcggcaata acttcccaaa ttttgataga tttacctgtt ttcttagctt
     7801 cctcgatgac agcaacagat ggatctgtcg gtacaaagta cgttgtcaaa tcaatagagt
     7861 gttcatctgt agccttctca ataacgcgac cttgttgggt ttgctcatca atgtattcac
     7921 cacccatggt tgtagtacca tcggtacgat aggctggcaa cagagcctga cttttctttg
     7981 gtgcatcaac tgattgtata aagtaaaaaa tcttttttcc tacaatcggt ttacctgttg
     8041 taatttcaat agttgttcct ttttttgtgt ttgccattta ggtccccttt aaaatagtgt
     8101 ttctgtaatg ttgatagcaa ctctatagac ttctcgtcct attgaattat ctaccaaaat
     8161 ctgagccttt atttggttat tgcgcccaag cagtctaagc atgcgagatt ttatctcttc
     8221 tgcatccaaa cgactatcgc caggtaagaa agcatcgata ttcaggctaa aatcatcaat
     8281 aactgctcca gtttgagctg tttttgacaa gtctgatata tttgtaccta caacaataaa
     8341 aggctctaaa acgtctgatt taggcaattt aaaatagatt ggtatgtcta aaactcccaa
     8401 tctatttttt acctttttta aatatagtgt ttccagtgag taatccatgc atcacctctt
     8461 aaacattttt ttgatattag ccattagcac aggccattct tttctcaggg cagggtctaa
     8521 aaacgattgt gcttccattt tacgagtacc taattcaaga taaatagaat ataaagcagg
     8581 agaaaccact ctatagtgta agagtcgttg ttgctcactg tagatttgag ctctcaacca
     8641 tccagtgtca accggggcta gtattttagc ctgtctctca atcctagcag ctgatttact
     8701 aagctcttta tctacagcga ttcgtactga cttctgcttg cgctcaacgc tgcgtaaaaa
     8761 cctatctagg cctctcatcc gataaataag actcatacat aaataaccgt gctattttta
     8821 tggtgtgcta gtccctttat caacctcgat tttcccttgt agataatctt gctaaagccg
     8881 tcgtaatggc cttgcaagtg caacttaaaa gcattcaaat catatttacc aaatagcccc
     8941 atctgttcag attttgtgaa agtattttcc atacagggga ttttcccgct aggtttttca
     9001 acagttcttt tatctagaaa atcgtcctgt tcatcgacat acactaagat tactctatct
     9061 ttatagatca ttgtgtatct cctaaataaa tcttgctacc cctttgcctg aatatacctt
     9121 cccaatagca gcgcttctga gtgttgattc atactcttta aggtaactgt cccacttaaa
     9181 agtctttcct tcttcgctat cttcaacggc tccttctgaa ttaatcctat taaaccgttt
     9241 aatagcaaca tcacggacaa taaacctcaa tctatcagga attttggtga tttcagtttc
     9301 tgagtattca ttaagtttag ctagcacacg ctctttactt tcatatatag caagggtgat
     9361 gatctcatct tgcgcaccat cacccttgga aatacctata aagagtttga tatcgtcaat
     9421 aagttgttta tcacccatat aaatagcctt taaccaccaa tgccgggtac agcagcagct
     9481 tcgattgttg cctctacaac cccttcagga atttcagcaa acagtacatt cgccccaaag
     9541 aaaacagatt cataggtaag attagaaagc tgacgattac gagctgcagc aattaaacct
     9601 gtctcatcag taaaatcagc aaacaagccg cccaagtctc cccctttaac atttaaagat
     9661 gcaaaaacta gattttctac agccgttgag tagattttac cctctggcac agatggcata
     9721 acaatcacat tttgcatacc caaaaagttc ttaagcaatg tcattccaaa aacattagag
     9781 gcatccgcac ctactttagt atctccaaga tagttagcta cgtctaaagg agagacaaaa
     9841 gaaacaagcg gggaaccctc aaactcatta aaagtagcta gcttagccca tgatgcagac
     9901 agcgcttttt gaaggccaac gcctttaact tttgttggtt ttgttttgag gaatgtaaag
     9961 aatgcatcct taattccatt ctgaagctca cgcataatgc gcttatctgc ttcagtaata
    10021 gcacgagctg caccatggcg agcaattgcc tcagctgtag ttgcacgacg tttcttgaac
    10081 cacttcactg tatagtcttt atctttagtt cgagtaacct tagacagagg gattgtttcc
    10141 ccttctccag gatcagtttg atctaaagtc acttcccact tataggtctg aatttttaga
    10201 tcgttagtta atgtttcacg acgagtaacc cctagcaatt ttagtaaatc attaatattt
    10261 ttggaaaact tgttaacaaa atcaattgat ttaatatctc ctaagtccgc catagtgttt
    10321 aagttttttt cagccataat attcccctct taaaataagt tacgattctc agcaattaaa
    10381 cgcatacgtt cgtcgtcatc ctctatcgcc atgatgtcag ccttagtcat accgaccgag
    10441 ccatttccag ttcgtggcgg tttctgagtt aaacgatcgt taacacgttt ttcaacagct
    10501 ttatcaaaaa tagtttgtaa attatcaata ttggccttaa cctcttctgc agtagtggct
    10561 aaaacaatat caataaaatc caatggcaat cctttctcca caagcaggga atgcgtctca
    10621 atgcgcatct cacgctctgc tactgctttt tcacgctctg cgatagcatc tagacgtttt
    10681 tgttcctcct ctttagcgcg ctcatctttt gacaacttgg ccaaacgttc accttctgta
    10741 cgagcttttt caatagctgc ggattgttca gattcccatt tagtgcgttc agcagccatc
    10801 atttttgaga tgtctgcgcg agtaaaagtt cgctcatatt catgcttagg atgttcaaca
    10861 gcttcttttt gagtgtcgac ttgctcagtt gtctctgttg ttacattttc ttctgccata
    10921 actttctcct agtggttacg ccaccaaccg atagtctagc tttacgtcct gcgacgaaac
    10981 agtgtagctt ttagtgtcat caacaaagtt tggacacaat aaaaagccgt attgctacga
    11041 ctttggtttc taaaggggtc gaattcgaca cggttaaact ttatttcccc cacttccgtt
    11101 tgtagttttt cttaatatag tcaaccgtgt caccaattgc cttgataact gattggttat
    11161 ctaaagtagc agctttaaca gtcgctaact cttcgtttgt tgccagagcg tttcgttgaa
    11221 cgattgattt tagctccatg atttgtttgt tttgattttt aatagcttct gcttgcatgg
    11281 cattctctgc aacaagcatc acaaccgctg tttccaattt acgttttttc ttaatgcgct
    11341 tattcattgt tttatccttc ttttttcaat tctgcaataa ttgacttaac cgctattgct
    11401 gcaatgccaa caatcaatat gagtaccaat acacctagtg ccactaatac catttgccaa
    11461 ataaacatat tttcctcctt gatagtttta atagggtgat gtataattga gataaagaag
    11521 gatgatggtc taacgcccat gaagcagttt actgtggagg cggtgggtca tcctccttct
    11581 ttttctaata cagctaatac ctcatcttta tttttgataa ttgatatatc aagaccccta
    11641 cgatctatca tataaatatg ttctaattgc cccattatct cttcaaatga taaaggggtt
    11701 tttgttatat caaaaatgat attagttgcc tgcttttttg cttttcgtag attgccatca
    11761 atgacgtttt tacccgaacc tgtgatttct tttagatcaa aaggagctcc atcaactaaa
    11821 taatcaggag tcttgatatg ttcaggggaa ttaactcttg gcaccatgtc aacttgcaat
    11881 cctgtctttt tggatagcca attagcaact ctatattcat aattcgaatg atcaagaacg
    11941 acactatggc catctacttt gtaaggagtg ccatttttta cgtactcatt tagtagtgac
    12001 agttgtggtt tatgctcatt tccatctatc caatctgagg tgacatcctt aaaatactta
    12061 gtgcttttat catcaattgg ttctacttca atacttagct catcttcatc aggaataata
    12121 gttgttctgc agttgaaatg atagggtgct acattaattc caggctttag ctcagataat
    12181 agctttcttt tgttttcttt agcaattgta cggcatatct cagttgtcct gtcatcaagt
    12241 ctaactaaat cacgataata cttaagtcct gcattcaagt agcgcctagc ggtagcatta
    12301 ttaatcacca tagttccatc agttctgatt agtgtttcag ccctgtgatt agcaacatta
    12361 aatcgcttag ctaaatctct ggccatcgct ctaggatgct cgccacgaac aaaaccttgt
    12421 tttaatctct tttgaagatt cttaacaaga ttgtcagtat tgccccacaa ctgttctgaa
    12481 tagttataac catcaaacgg ggttctaacc agttcttcta aaactggacc attgattgtc
    12541 cctgaccgtc cacccattgc ttttttataa gcatatgagg caactttttt taaatgattt
    12601 tcaaatgctg aatcaagtac accttttagt atccccgcac gataaacaag ctcaagattt
    12661 aatgcatcca tccttgtagc tcttgctgat acatactgct cattaagtcg ttttagcagc
    12721 tcaggatctt tctcagcttg tttacgatac ttgttagcat tagctacgta atctgataaa
    12781 tcttcatgac gtagtttttt aacgacatcc tgataagtca ttttgttctc ttcagaatac
    12841 ttagtataaa aatcaaacaa ttccttttgt aactcaaaag cctgttcatt atataacttc
    12901 tgcagttctg aaaagacatc taaatcagtt ctgtctaaat aacttagaat atcttcttga
    12961 cgcttttgcc agtaattaag gcttttctgc cgttggttct tcttgaccac tagcatcacc
    13021 taccaatcta ggctccggta aagattgctt tttatcagct tcttctttca agcgttcaag
    13081 ctctgcttca gcatctactc ctgtgacagt atttaagatt tcaaagatag tctgatcgct
    13141 aacaatgcca taaagatttt gtgcagctgt aacaatttca ttattgtttt gaggaagatt
    13201 aggtgtgaaa actatactcg tatcatttac aaggctatat gtagttgctt cattcccttt
    13261 gatggcccag atattagctg ctaagcgtaa gcgtcgcatt aatccttttt taaacaacct
    13321 ctcttgcttc tcgcgatagt tgtcagaagc cataagctta tacttcattg attcaccaga
    13381 ttgaactcct gaaaatttca tatcttgtgt atctggcgta aaagtaaacc tcaaaatgtc
    13441 tgcaactaat ctatttttgt aggcttcgct accggcggta tcatactctt ttttgagaaa
    13501 gtacgcttgc ggtttaacgc catttggatt aggattatcg tctaaaatta acacttgggc
    13561 ttttttaaac ccaattgaga tcgctaaacg accattagga tttaatcggc catcatctaa
    13621 gtagtcattc tcatcagctc ctgtgtaagc attaccagct attacaagca acgcattgac
    13681 tgaatcttgt tgaaagttag caagctctga ttgagataaa tcataggcgt caatattatc
    13741 aagtacagac tcataagccc ccgttcgctc ctcgttatta gcgtattcgt tgactggtac
    13801 acctttaaaa aaatgtcctt cataatcttt taatcgcata ccttttgttt caaggttata
    13861 gtcttcgtag gtataaattg tgtcggaagt atatgctttg ataatctgtt tacgtttacc
    13921 tgagccgtaa tctatgtcgt agaaatgaac ggccatcaac gaatttcgct ggtatgtatc
    13981 atcatagata acaaaagttt gctcggccgg gagctggtag agttttactt cggttttttt
    14041 gtcatctatt ttctcaacag ttaacagctc gtaggctctt ccataaattg ataaatctgt
    14101 ttttattttg acgttgtggt agtcctcatt gtttctgacc gacataaggt caatagctgc
    14161 ctggaggtct ttattttcat ttttgtactc aacgggaacg ccaagcatat aaccttgctc
    14221 aaataccgta atatacttag caaaatcact tgcaatacga ttatccgctg cgtatttatc
    14281 tgttttagca ggtctatact tgatgttatt atccccaaga tagtatcgct ttaactcttt
    14341 caaacgctct aattgttctg ctttaaacct tgaaatgtaa ttcttaagtt gatctatcca
    14401 aagttttgat tcatagtcaa ttgcttcaaa gtcttcttgc agcataataa attgcttatt
    14461 agcattctca ttaaaacgag ttcctgctaa aaattgtttt tcttccaaag tttcacctca
    14521 ttcctaaaaa taatatttag catttttcat gcgcttactt ctatccgccg actggtatat
    14581 tctgtcttgt acggcatatc ttatggcatc aatgcagtgg ttatagctgt caactggttc
    14641 gttggtatac tcattagtct tcttgtcttt cttccaagtg taattttcga gttcttcaat
    14701 agtcttgaca cacctttcat caacaatcca atcatattga agcaaatact gtattccttg
    14761 cataacggtt ccaggccctt tggtaacatc aatcattcta ggaataccta aattcctcag
    14821 ctcttgatta gatttctttt cagccgaatc tcctctgatt tcttctttgg catagccgag
    14881 gtcctttata gcatttgcta ttttgtcatt ggtcaaattc ttcctgacat attcctctaa
    14941 gatgtataac ttcttgtttg cgtcatcgat tttaacatgc aaaagtgccg aaggatcatt
    15001 gataaatcca tagtccaaac caaaaaaaga aggcaagtat gataacttgt ctttgtttaa
    15061 tatttgcttg tcatatttgg gaaaaattag tttatcaagt gtagcaaact ggccaagagc
    15121 atatattttg taataagctt cattcctatt ggctagttcc tcgatatttt ctctcgtgac
    15181 atcatctaag aagcggttgt ctttataagt tgtttgatag acaactgtat tcttaggtgt
    15241 cttaacgaag aaggctttat aaacccagtt tacttttgat accgggttaa acatcaagta
    15301 tatttgcttc tctagatgtt tcttatctct taaacgcaag gtcaactgcg tataatcatc
    15361 aagcgtaaac tcactagctt cttccataac cacatcagat atacccttaa ttgacttaat
    15421 cttctctggg ttgtccatac ccttgaaaat gaattctgcg ccatttggga gcgttattct
    15481 aaaagccgac atatttatct tacatttatc caagatgccg aaatacgaca aattagacat
    15541 gatatcagca aatacagagt ctctaacagt tgcaccgact tttctgagaa ctaatatctt
    15601 tctgggatgt ttgaatttag ggttaagtgc ttttaaaatt atcttttgaa aaacaccgtg
    15661 agactttccg ctagacgccc caccataatg aacttccgtg aagttgctat agttgtaaag
    15721 tttgtcgtag atatgtttgt taaaaacttt gctaggatgc ttgatcacga tattaatttt
    15781 agggcgctgt ttagtcgtca tcccactcac ctacgttaat ggttacatct gagctgacat
    15841 ccatttcaac cttgtcagta aataacctgt accgtttgcc tagtagctca gctgccttga
    15901 ttctatcctt ggcaccaaca tcgatgtcaa ctatcttctg accaaactct ccaacgctaa
    15961 tgagcgtctt ttcttgttgg tctcctcgca taattgaagt gagatattgt aggacttctt
    16021 cttgcgtagc aatcttttca gattcaagtt tttcaagccg ctcgtctata taagctttaa
    16081 tgtcaggttt ggtcaagttt tcttgaccta ttgaccttgc tgtcttttta ctataccctg
    16141 ctttaatagc cgctgctgtc gcgttagctg agatgatgta ctcatctgca aaacgcttct
    16201 gttttagggt taatttactc aattttccat cacctccaag catagcaaaa aggcaagaca
    16261 ctatctgcct taccttcaaa ctcatactac caatttatca tcaaaaagat gacaattcca
    16321 tacatttttg tgtcacattc ctattttttt ggaaaatatt tctagaatcc gctctctttt
    16381 gcggtaaata gacttacgcg acagatgtct tgtgtaggca atttcttccc aagtgttact
    16441 tgaaccaacg ccccacctaa gattaaaaat atcagttagt tcttcatcca aaagatttaa
    16501 cgttgcaata actgcttctt tgaaattgga tagacccttt agttccctat ctgaatccca
    16561 ccttgcaacc acatcctcag taacttttga aacaaaattt gttcttcctc caccgatatt
    16621 tttatctacc gcagtattca tatcagtttg tagctcaagt tttcggagtg cgatcttgtt
    16681 atcaataaaa cgataatcaa acagccattc gtcaaaagct tttaactgtg cattagataa
    16741 tctgctcact aagttttacc tcctccagag tcatcttata cgtcttcccc tccgctttaa
    16801 atgttcgact ggattttcca ccagaacaca tccacatcaa gtcaaacgct gccgcttgtg
    16861 ctttatcaaa tctgtccatc cttatccccc atttttcgtc aattctgcaa ttctctttgt
    16921 ctgtctagct ctatcatcac tagcacgttt aagctgcttt tgtgtcctac ttagctgagc
    16981 acgtagtccg tatatttgcg gctcgtagta acttttaagt gatatgccaa gccctgatac
    17041 gacaatcagc agcataactg ttagtgcagt gataatgatg tttttctttt tgattgcttt
    17101 gtcttttttt actaactcat aaagcaagca atcaatcatc tgttcttcag tcattctccc
    17161 gctccctagt atatttttct ttaactgttg cttcgcaaga atcccaaaac ctcagcatgt
    17221 ctgcttttcg cgtaaaggtt ttctcttcaa actgaggttt tgcctcaaaa ttcttttctc
    17281 tacccgtgta gattctaacg acatattctt ttttcatcta gacccctaac tgcgccttaa
    17341 ctgcttcaag taaggcgttc tgattttttt ctttgccttg taaaatccta agtacttttt
    17401 catcaactgt attttctgca acaatgtggt gcacaataac gggttctgtc tgcccttgtc
    17461 tatctaatct ggcattagct tgctgataat attcaagact ccatgttagc ccaaaccaaa
    17521 caataatatg cccgcctttt tgcagattaa gcccatgccc agctgattga gggtggcaca
    17581 gaagaattgg tatttttccg gaattccact tgtcaaccga cgtcagctct tcagcctgag
    17641 gaaatcgttt cttaagtctt tcaagatcat gttgatactg gtaaaaaact aagattggct
    17701 ggccttggct ttcttctact atgttctcaa gcgcgtcaag tttgtcgtcg tgtatagcaa
    17761 ctgttgcttt atcatcatca tagatagcac cattggccat ttgaagtaat ttattggcca
    17821 aaaccgcaga attagccgca gatatttctt tatttttaaa ctccaacacc aaatcagctt
    17881 caagctgttt gtaggctttc atattagata acttaactga tacaacgtcg ttggttcgcg
    17941 gcggtaactt gagatagtct ttagctttca tgctgacaca gatgtcctca atcttgttat
    18001 agatttctgc ttctgcacca tccctaagtg cccaactgta aatgattgga ccattacgct
    18061 tatcaggaac aaaatacttg tctttaaatc gagtctggct cgtctcaagc ctgtcgcctc
    18121 tgtccatcag ataaatctgc ggccacaaat caatcaaact gttaggcgct ggggttcctg
    18181 ttagtcctac aaggcgttgg actttcggtc taacttttcg caaagcccta aaccgttttg
    18241 acttactaga cttaaaactt gataactcat caataaccac aaaggtaaac ggccatttag
    18301 tcttgtagta ttcaacaagc caagtaacat tctcacgatt aatcaaatag atatcggctt
    18361 ctgtttctaa cgcttcaatt cgttttctct cgtcccccaa aactttagag taggtgaaat
    18421 caaaatgcca tttcccaatc tccgttggcc acgtttcttc cgccactttt ttaggagcta
    18481 cgattaaaat cttatgatcc tcggaaaaaa tattttgaat ctcatctatt gccgatagtg
    18541 ttgtcagcgt tttaccaagg cccatgtcaa gtaaaaggcc acaataaggg tgctctacta
    18601 tccatgtctt agcgtattct tgatactcat gcagtctcac acccagttct ccatttcttt
    18661 taaggctatg tccactgatt cgtaggagtc aacaacccaa acgtgctgcc cagccttttt
    18721 tatttttttg tgcattgcaa cttgactggg tcttggtttt ttaccaggcg ctttgacctc
    18781 tacaaaaaag gttcccgtgt tcatgacaac aattctgtca ggcactccta tcgtccctgg
    18841 acttgcaaat tttaaacaca gcccttttgt tttctttttc aaataatttt caatgtcttt
    18901 ttcagtcctc atctttcctc ctttggtcaa taaaggtcag ggttaccgtt tttttcaact
    18961 tattttctct tttttatata tgtgttttat atatgcctta ttttatatat atttattttt
    19021 tatatttata tttaagttaa tagaagaaaa gtggtagatt ggtaaccata ggggctaagc
    19081 tattgctatg aaaggtttct tagggctacc aaaaagctac cagggctact tttcgaaccc
    19141 atttctaagg gtcgagttac taagttaccg atttttccaa ttcagttttg attttttaaa
    19201 aattattttt aaatttttta tttttaaagt ttgaaaaacc ggtaacttgg taactttttt
    19261 ctagggttac caaactctaa tcccaaaaaa gtaaccccta aaactcactt tttaacttaa
    19321 aaccgaccca atttttggct tgctttcctc cagatttaac gtttttattt tcataattta
    19381 actctcttag tcggtggtta aatgcatttt ttgccaaagg tttgtagcct gaatcctgac
    19441 aatagaattt ataagctggg tagacatctc taacaggaac tttgaagtct tcgccaagtt
    19501 cacactcgtc ttcaaggaac atagccacga catcgttgcc tttttcccat ttctcgacac
    19561 ttgaccccat gctggcacta atactgaaat ctcttttact taaggccttt ctaagcccct
    19621 ccatcgctct gttaaagata ccaggcacct cgcccataat cttatctagg gggtattttg
    19681 ccttaacttc ctgagttaat accttatcca tctcaaggat catcatgcgg cgcttaagtc
    19741 ccccactgaa atctcgcata ggtgggagct cattcatggc aaaagacagc ttagcataat
    19801 tgtaaaagtt aatcggctct ttatttttac ggtctgcgtg aatagtatcc tcccccgtca
    19861 acattttaag tgttgcgcca tctgctaagt attgaggttt agcatcggta tcgaagttag
    19921 cagtctttcg atataagccg atttttgcaa agcgttcttg catcaggtac tgcagtgtca
    19981 cggctgagta attatcagca cctatcattt cacgtaaaat attaatcagt gttgatttac
    20041 cagtaccgcc gctgccgtag atgaatagca ttttttgaat agcatattcg cgataaaagt
    20101 tatagccgaa ccactcaaag atgaaatcta tattttcagc tccgacggtc tccctaagaa
    20161 aaccctcaaa ggtttcacag gccgcctcgg ggtcatagac aacgggatgg cttgaccttg
    20221 catgcaattc tggatcaaac ttagtcttaa aactgttatc cctcaagtca tagactccgt
    20281 tcgctagcac tatcttgtta agatcgctct cagtaaacac ttcgcttgag aaagcctgtg
    20341 ccttaatcgc tacgacggtt tcgctaatgt gcctaatctt agtaatttta ccgagtttct
    20401 tagttgagat ataactcttc aaatactcct ctgcgtttgg caaccagatg ccttttttag
    20461 cgtcgtagcg taaaaattct aagccgtccc aataaatcgg aacctcctta ataatctgcg
    20521 ttgctagcaa ataactattg acctcaggtt cgcccctctc atcaatttca agccagcttc
    20581 tgtcatcttc gactggtaac tcttcatcga aatcgcctaa agcctccgcc attaaatagt
    20641 ctttaatttc gggtaagtca gagacaaaag cattcatcgc tttacttgat ggcaacttat
    20701 tagtaggagt aatatcttta gtctcgctat cttgctctcc gaatttatgg atacgaacaa
    20761 ggtcgtatgc atttacaagc gtatccccca cgggatctgt cccgtgatgg ctataagcga
    20821 agacatcatc atagatgact aagccatttg cggttgaacc ctcagtgtag gtgtacctat
    20881 caggagtcgt tccttcttca taaacctcgg gcaagaacgt tgcaatggcc tgtctaatgt
    20941 catagttacg acaaaaggct ccaataagcc cttttttact aagtgggtca ccttgttttt
    21001 tagcttcacg ctgtctttta acagcgtgcg tcgggctttc tggccagaag cttgagtcac
    21061 gccagtccgg gtatgtatca agcacctcat caacacttag aaaagcctcg tcgttatatt
    21121 taaacgtaaa gtcagcatct ctcgagtggc tcggccagaa catcaaacgc acactttgat
    21181 aagtcgtgtc atcaaagttc gacatgccta gttgattagc caagtaccta gcgactggct
    21241 catattcatc aggcatcatt aaacggtcag tagggataat aagacggtac ttagcagctt
    21301 tttttgagtg gctgtgagta ctgtagagta cgtatgcata gtctgcaagc aggtctagcc
    21361 tatctaagaa atctttactt gggctatctg cgtcaagcgc aaccaaggac ctactttgaa
    21421 cattttcgtt tttccgttta ccctgcttta gccacccgcc gacaaaacct cctacgtctt
    21481 ttgcttgccc tttttctgct cgagacatct tctggtactc cgcaaacgtc tcttgggtga
    21541 ctgtaggttt ctctaacctc tcaaccagct cctgccaagt tagcgtaata tttttccacg
    21601 tcttagctgt tcgtgaatta cccgttgcga tatgaagctc ttgcagagga gaagacttta
    21661 ctattagttt ttcttgcttc atctatctaa tccttcatat aatactttgt tacgtagcct
    21721 tcgctattta aaggaagacc ctccgcccat tcaggagcct gagccatcaa atcattaact
    21781 tcttcgattg tcaggcctga gccttcgata atagcctcat catgaacgtg gaaaacaaca
    21841 ccatagcctg cagcttcaat cctcagaagc gcttcagcta gaatatccct ggccgtcgcc
    21901 tgaacgatat tttcgacaag cttaccgccg taagtctctt gcgctgtgaa gtaggcctta
    21961 tctccttggc cctcatagac gattttgtct ccatagtcgc ctggctcaac cttggctctt
    22021 gcataagcta agttcctacc gctaggcaat gttataaaga ggaaaccttt acggtatcta
    22081 aatcgtagtt ttccaagttt tattggtgct ctcgatttga tagctttgat ggcggctctc
    22141 tgcacatctt tccaaaattg gacgattttc ttattggccc tgcgccagtc atcaactagc
    22201 ccttggagct cctcttcctt gactcccata tttagagctc ccatctgctt gagcgctcca
    22261 ggacctcctt gatagccaag tgccaactct gagattttgc ctttttggcg tagttcctta
    22321 tcaatctcct caattggaat tccgaacatc tggctagcgg atgcctcata gatttttccg
    22381 tgcgtcgaaa acacgtcaag cctccactgc tctccggcaa accacgcaat caccctagcc
    22441 tcaatcgctg agaagtcaga gacgtagaag gtacagcagt ctttggccac gagtgccgtt
    22501 cttacgagct gctttaaagt gtcgttaaga ctatcgtata aaatctccac agcatcaata
    22561 tcacgctttt taacatactc tctagcatca tctagatcct ttatataatt cctagctaag
    22621 ttctgtactt ggacaactct gcccgcccat cttcctgtcc tgctagctcc gtaaaactga
    22681 agtagtccat gaactcgtcc gtctgagcac atagctcttt ccatagcttc atattttttt
    22741 agacttgaca tagcggtttg tagtttaagt tctaaaactc tcttaagttc tccttcggcc
    22801 gtcttaagct cctgctcaac atccgcttta gtcagaccat taaccgaata accgtgttct
    22861 tttagccacg gtaacaactg cgccctgcta ttaggattat caagtcctgt tagagctttt
    22921 agttcaccag acaaactttc catcttaaca tctttgcaat acaaggccga agcaactaac
    22981 tctttatcaa gcgccacgcc tctgtcgttg attctctggt cgcatgcgta gtagtcccat
    23041 tcacggtcgt gcacaggaac tgactctagt ttttcggcaa ttgccatctc aacaacaacg
    23101 tcttggatgc agtagtcaat aaacatttgc cacttttcgg gggcgtgttc tggtaagttt
    23161 ctagttctcc caccgttagc tttacttggt ttgcaaggca gggaaaagta tctgattaag
    23221 tttttacccg aggtatcttt ttcctgcgct aattttaaat acagcgcaca cttttccaag
    23281 cttgaaggca gccccaactc ttgggccagc accatggtgc attgccattg gcaaggatct
    23341 agatagtaag gtagaccgag gtaacgactg agacaaactc tttcaaattg ggcattaaag
    23401 gcgtgctttc ggactttatc atcaaataac atatctttga tgtcttcagg tagagactgc
    23461 cttgtcaaat caaggcactc tacttctccg ccatctatag agtaagcgaa aagtaaaatc
    23521 tcaaaatctt ctgcgtcagc gtacttgtaa accccatttt tgatgtcatt cgaactatag
    23581 gtttcaatat caatatttaa atgtctcata cctctccttt aaaaatgagg agcctctaaa
    23641 gaggccctct actataaaat gtcgtcttcg tcctcttctt cgttccactc gtcaaaatct
    23701 gcatcagctg acgaacggcc gccaaggtag tctcctttag caacaatttg gacgttgttt
    23761 aatccgcaag agattccttt atttcccgct gtgttgtaag cataggcatt aagtgatacg
    23821 cgagcataga cgccagagta aacttcatcc gctgagtcaa cggggttttt atacttgtca
    23881 atgatttgtg gcttagtttt acttgacact gacatgaaca cgtgtccagc gtactctggg
    23941 tgctcttcgg tatccatttc ttcgtcgccg tcacgaagcg ttgtcttaac gcgctcccat
    24001 ttaacccctt tgagtttatt gtccttggca gcctcataag cagctttctg cgcgtcttta
    24061 attttcttga ttgtgacttt gtctgttttt ggaattaaga taactgttga atacttagcc
    24121 tcttgacctt caaaggcttt aggctctagt aaagctacat agcttaggcg tacttttccg
    24181 gttactactt tagttgtgtt tggtgtcata attataattt ctcctattca aaatctttaa
    24241 ttgcttgttc taagctattt aatgcggggc gcttgtcgct atttttaaca aggacaggtt
    24301 tgccctgtgg tttatcaatt acttctgcta ataaatcagc aaaagtggtt ttacctatta
    24361 acttttcaag agttcccatt gctaacagct ctttcggttt aaaaatctca tcgtcaaagc
    24421 cgttatcttg taaaatatca attgctttgt ctttatcagt gatgactcga ttacttctac
    24481 cttcaacaat cttatagcct ggaacttctt ttcccgagag tgcttctttc agggcatagg
    24541 cttcaactga ctcaacccac ttcttgatag ctgaggcttt gtcaagaatc tctgcgacgg
    24601 cttcatcaga taaatagaca ggctcctgat agtcatattt atcaattaat tcccaatttt
    24661 cttgcgctct tggtaccaat ttagctgcga caggagacca ctgcaatact ttttcactta
    24721 ggttccagtc accaatgcct gcgtctgctt gagcggccat aggcaagaca acattatccg
    24781 cccagtagag taactcctcc acgtaaatgt caacagaact aaccgaatct aaacgtggct
    24841 gaataatggt cattttgata cggtcaaagt cataaaccat atcgtaggaa gcataagctc
    24901 ctagagcgta cagccccatc tgtgggtttt ggttagcaga cacaggcatg cccttgccat
    24961 acttaagatc aataatttca atgaccccat ccgctaaaat gacaacatcc gaagtcccaa
    25021 aaccgccagg cacccagtcg ctaaaatcaa cccgtttttc aagttcaatt tcggcgttct
    25081 cataagcatt taggtgctcc ataacaatat ctgtgtaaag ttccgtcatc tcttccatct
    25141 cttcgttgta gaagtctgag ttttccttaa aagccttggt taacgtgtta aatttacgct
    25201 tggtgatttt accagacttg tacatcagtt tgatttcaga aagctcatgg gcgcttgtgc
    25261 cctcttgagt gtatacggta tcgcggctag gatagtctgc ttctaatctc ggcagcatag
    25321 ggcaataaag ccatctgtga gcactagaag cagacagtag tgcgtgattt tctactggca
    25381 ttagagggcc tccaacttct caacaaactc agcaaactgg tattcttcaa gttcaccaac
    25441 ttttgcgacg ttcatctctt tcaagacttc cttgatgtcc tttgacttcc cttcttcaac
    25501 cttggcttta gccattttct taatatcagc taatgtcaaa gttacagact cttctttctt
    25561 tttaggagct ggtttttctt caacaacatc cttggttact gtcttcggca tatccagagc
    25621 ttcacgcata gcatcgaaaa cacctgccat gctctctgct ttaaaagtta cttcaatcat
    25681 tgtgtttctc tctttctgtg ttataattta attgtgtata attgttgacg gtttcctaag
    25741 ccgtcttttt tgatgcaatc aatagcctca cctccccaaa agtcctttaa tatcaagaat
    25801 gtctttagca acctgactac gatagtgtgg gctatcatgt agacctttct cgtagtaggg
    25861 attaggcaca aactcccaat ctccgcccgg caactcaact tcgataactt cgttatcaat
    25921 aatttctaac tcacgttcaa gataaactag tgcgtattct aaatagttca ttttctctcc
    25981 tcaattactt gttttaaagc tgttagtata aaaactgcgt ctgctaaggc ttggttttgg
    26041 gagcaagagc cccccctgac gtaaaatatc atttaagcca gctagggttt catcaataaa
    26101 ttttagtgat atattcattt ctttttaccc cacaaaaatt cttgccatga caaagttgca
    26161 cctttaaatt ctttctcagc caacttaaca aagttcctcc tatcctggtc ttctttaaaa
    26221 gtttccttag ctaatcgtct ccaaaaggct tttcttgtcg ctttacgctc taagaaagtt
    26281 tcactgaatt taaaatcatt tccttgataa agagcttcat atctctctac gtcatttaac
    26341 gtcggtagct caatccaaag catcaatttt aaatcttgtt taatagaacc caactgagca
    26401 gataggatag gtaagctatc tcgtctttca gcttcaggtt taactaactc cccctcaatc
    26461 cgattaattt tcttaataat cttttcaaaa gttgtcatca ttctgcgcct cctagtttaa
    26521 tgagtttgtc aataatacga agtttttcct ctgagtattt cctgtaacta attctcaaat
    26581 ttaacaagag ttcctcgtcc gagatttcgc cagactcgtt taagtcaagt aaagcctcaa
    26641 ctgtgctctc aaaatctgtc gcattttcca gtagttgttt ttgtaattcc catttagaca
    26701 taacgttctg cactccattt cttgctgttt tctaaagcta cttccctaaa aatttttcgc
    26761 ttattctctg gcgagttgtg ttttttgatg acttcatatt gtatcctggc aacaattgct
    26821 aaagcaacag ttgttactaa taaaaataat tctaatttgt tcatgttata ctcctactct
    26881 tttttcgaat ttaatatttt caagcatttc tgccagggtt tccttcttgg gtttatagcg
    26941 gttacgactt ttccatttaa caaataaacg gaaaccttcg taatcaatga atacgatttt
    27001 atgcgttgga tttaatacaa actgtttaaa gtctggatga tcacgcattt ctgtcgccca
    27061 aaccttagcc gttccgactg tcaaaccttc ccagatttgg caaaggtgtt catagtcacc
    27121 agcttctgct ttttcagatt gcttagctgg tctgtaaact aattcagctt ttggcatttc
    27181 ttacctccaa tctgtgatat aatgtaagta gaatttttga taaggggctg actgcaatca
    27241 gttccttttt tgcatttact caatgctgta atctgcaatc actcgcagaa taaactggtt
    27301 agcctttggt cctctagttg agccactaag aatgttagtg acctcttgac gattgagacc
    27361 ataggctgct gctaaatcac tcttcttgat attgttactt tttaggaagg taacaacttt
    27421 ttctcgtcca actgcaatat ctggcatatt ttctcctttc ttttctgata taataaaaat
    27481 aaaaacttga ggtaaaaatg tctcgatact ctgattataa atacgctaat actatcctta
    27541 aaagtattga agaacgacca gaaaaatatc tgattatcca ttactcctgc gaaagttttt
    27601 ataatctagg tggtaaaagt cctagaatag cttccatttc agttcgtcaa ttcaataatg
    27661 cccaaaccaa caacttttcc attcatcagt actccgagat attagatacc ccaattactg
    27721 atgatactta tgaaactatc gaaaaagagc tgttaacaga tttcttcaca tttgttgaca
    27781 gaaataccga caaaaattgg attcactgga acatgagaga tactgtcttt ggctttcatg
    27841 ctattgagca gcgattcaaa gttctaggcg gcacaccaat aatcattgat gatgacaaaa
    27901 agatcgattt agcctatctg tttaaaaaga tgtacggtgg aggatatatt gacaatccgc
    27961 atattgaaaa attacttgaa ttgaacaatc taaccccaca tcgttttctg acaggtaaac
    28021 aagaagctga cgctttctct tcgagacaat accatgaact aagtatgtca acatcaagca
    28081 aggtcaatag cttttcaaca ttcctcactt tagctatcaa cgatgattta aaaactaaca
    28141 cccctaaatg gaaaatgaga ggaactaacc tatctggatt actttccact tttcaagaaa
    28201 caatctcagg aaaagtgata atcggtataa tcaaccttat tgtcggtgga atagttggtg
    28261 caataattgc aaaatatatt caataaatga tttattttga agtagaataa gttattgtcg
    28321 tatttgctct acttcttttt ttgcatcctc tttggaaata agagtcggat tgtcgtacca
    28381 atctctttcc acgtaaagtt cgttttcttt cccctctaag ctatcagcga cccactgaaa
    28441 atgctcttta cgcttttgta gatcaacgat gttttttttc atttttcctc cttgttttaa
    28501 aatttgtaaa caagaaataa ctaaattttc aactttttag tatatgacca cttgacaact
    28561 cacacctaaa aagttagaat taaagcatat taaagaacct taacaaatca acttaaactc
    28621 gttcgccaaa actgttttat agttgtttgc ttagttgttt ttttagttat ctcttgctta
    28681 caaaaaatat gatacaccca tttggttgaa ttgtcaacat ttttcaccca aaaagttgaa
    28741 atattttttg tcatgcctta gaaaggttga taaatcaatg tttccgacgt ttgaaaaaat
    28801 caaagaattg tgcaagcagc gtggaattac acttattcaa ctagaggaaa ctttaggata
    28861 tagccgaaat acactctata agttgaaaac tcaaaaaccc aacgctgaaa gaattgctga
    28921 aatagcagac tacttcaatg tttcaacaga ttatttgctt ggtcgcactg ataatcctgc
    28981 tattgctaat ggcaccccta gtcaaaaaac aatagacttt aaagagatag ctgctcagtc
    29041 aatgtcttat gatggaaaac cacttaccga tgatgatatt gatctcattg cagcagtctt
    29101 agaacaaaga ttcaagaata gagattaact atggacttat cacttcaaga gtatgtcaaa
    29161 ggtcacggtt atgagctttt attttatgat aaccgtggca cagataaaga agcgtttgct
    29221 aaccatgact gcaaagttct tggtattggt tcttatcttg atgatcatga aaaaaagaaa
    29281 gcaatatatc atgaaatcgg tcataaagag cataccaaca gacagtatga actaaataga
    29341 gaactgtgtg aattagaagc agacagaaat atgattcatc acttgctaaa agaagagtta
    29401 tcttatttag acaatgtaaa tgaattcaac tatgctcgtt tcatggaaaa atataagtta
    29461 aaaacaattg ccgatgaaaa aatggtaatt gatgaatatt atactttaat aggttaaagg
    29521 agattatcat gggatttttg gacaatgtaa aagaagctag tactgtttcg actgcttctg
    29581 gcgaaaatta tgaatatgtt gtgctacaag ttacactaaa agaaaagctt ataggaacag
    29641 gctcaggaaa tttaactgaa cttgaaaatg ttattaataa gcaagcaaaa aaaggatatc
    29701 gcctacacac tattaccaca tcaaatggtg gcagtaaagg atttggtggc ggagatagaa
    29761 tacaagctac aatggtattt gagaaaatca agtaaaataa aaaaagccct acgctcaaat
    29821 tttggtcggt gcgagcgtga ggcaaatcta gtatagtaaa aacctgcttc gcagtaggtc
    29881 tctttactat acctatttta acagaaaatg aggtaaaaaa caatgtggtc agaaaaacac
    29941 aaaagcggaa aagtaaattt tgtagaacgg tacaaacacc cgtatactgg caagtggtgc
    30001 agagcttctg tccttatgga aaaagacacg ccacgaatac gaaaagaagc ccaaaaatat
    30061 cttgacgaaa aaatatctaa aatcttaaca agtcttacca caaccgatgc ctacctacta
    30121 gatgtcatga acgaatggtg ggaacatcat cagaaatcac tcaaatcaac ttctgtccgc
    30181 tctcttgatt ttagaataag agaattgcga aacttaattg atccagaagt gatgattgcc
    30241 aagataacca cgaaatacct gcaaagtatt atcgacaaaa taccaggtag ttatgacaaa
    30301 cgtaaacgag cacggcagct gctcaaacaa accttcgact acgctatcgc tttagagtat
    30361 gtctcaatca atccagttat tagtacccaa ctcgcaaaac ctgttaagac catcaaagac
    30421 tttgaagacg ttgcccagaa gtttttagaa aaagatgaac tcaaaaggct attagatgaa
    30481 atgtatagac gtaaaggatc gattaaaatg gcttatctgg cagaatttat gagcttaaat
    30541 ggctgccgca ttggagaagc tctagctata cagccagaca atatcaaaaa tgatatcatt
    30601 gaaatccacg gaactcttga ctacacctca aatggctata gaaacgctat caaaaccacc
    30661 cctaaaacaa attccagttg gcgtgaaaca ctgataacca aacgtgaaaa agaaattatt
    30721 caggatatac tgaaaattaa tgctcttgaa aaaaatacta atcctaatta caaggacatg
    30781 ggctacatct tcatttccag aaatggtgtt cctattcaag acaacgccct caacacctct
    30841 atcagagcgg caaataagag actagaaaaa ccgattcaaa aagaactcac cagccacatc
    30901 ttccgtcata ccctggtgag tcgccttgca gaaaacaaag tgcccttaaa aactatcatg
    30961 gatagagttg gacatgctga ctcgaaaact actcaacaaa tctataccca cgtcacgaaa
    31021 agcatgaaaa atgaagtcgt cgacatctta aatcggctat aatatgcccc aaaaatgccc
    31081 caaaacacaa gaaaaaacct tgacatcttc aacaaacgtt gatatgacaa ggttctttaa
    31141 tgttttattt aatcacttct tgagttttag catacttggc ttctacagca tctttttctg
    31201 ctttccacca tgtctcattt tctgtatacc acttaatagt ttcttccaaa ccttctgaaa
    31261 agtttgtaaa ttgtggttcc cagccgagtt cttcacgcaa ttttgtagaa tcaatagcgt
    31321 aacgaagatc gtgaccagca cggtcagtta cgtgatcata agcgtctttt ggttgaccca
    31381 ttttctcaag gataagctca agaacttcct tgttgttttt ctcgccgtcg gcaccaataa
    31441 ggtatgtttc accgatacga cccttagtca aaatagccca tactcctgta gaatgatcat
    31501 tagtatgaat ccagtcacgg acatttttcc cttcaccgta tagttttggc ttgatgcctg
    31561 ataaaatatt ggtgatttgg cgaggaataa atttctcaat gtgctggtaa ggtccgtagt
    31621 tattggaaca atttgaaatg gtcgctttca caccgaagga acgtacccat gccttaacga
    31681 taaggtcaga agctgcctta gttgatgagt aaggtgatga tggattgtat tttgtttcag
    31741 cagtgaattt ttcacctggt ccttcaccct gtcctggaag gtcttcacga agtggaagat
    31801 ctccataaac ttcatcagtt gacacgtggt ggaaacggat atcgtattta cgagctgctt
    31861 caagcaaagt gtaagttccg ataaagtttg tatggataaa tggacttgga tcttccaatg
    31921 agttatcgtt gtgactctca gccgcatagt gaacaatagc atccgttttg gcagccaatt
    31981 tgtctaccaa ttcagcgtca gcgatatcac caacaactaa ctcaacacga tcaccaagaa
    32041 tagcttcaat gttagcacgg ttacctgcat atgtcaattt atcaaggaca gttacatgaa
    32101 catctgggtg gttattgtag acatagtgca caaagttaga tccgatgaaa ccagctccac
    32161 cagttacgat aatattttta tacataagat ataaagggac ctttcgtttc cgaaaaaatc
    32221 tattaaaagt aataactcta acaaagacgt tttaggccta agaaaacatc gctttctaag
    32281 atttgagtcc catgttcagc tcaaagagag aaactgaact ttcctttcat catttttagt
    32341 tgttacttgt tacctgaagt agagaagaat aactcccctc atatccacct caaatgatta
    32401 atcccaatca tctgagtatg ttgtttccct ataggtcttt tggtttcagt ggtttgacat
    32461 cactaagaag aggatggttt ttatctgctt cagaaacttc tgcagctgct agattttccc
    32521 aagtaatccc aagacttggg tcagcatagt ttacaaaagc atacttaggt ttcaagtcaa
    32581 gagcccagta gtcattgaca agataactgt aagagacagt ctctgaaaga acttgaaagc
    32641 cattagcaac ccctctagga acaaacattc cttttgaagc atcaatcact gtctggtaga
    32701 cgtttccaaa agtctctccc tcacgaagat caacccaagc tcctaaaacc ttgccatcat
    32761 cagcaactga gatgtattta tcccaaggtt cagcatgaag tccacgcagc acatgctgac
    32821 gtgaaaaaga aacgttgttt tgtagttttc cttcctcaaa aaaacgttct ggaaagccaa
    32881 ttggcaacat tttttctttt tggaaatttt ctttaaacca gccacgatta tccccacgaa
    32941 caggaatatc aaactctagt aagcctggga tttctttgat ttctcggcaa gccaatggtt
    33001 tgtcaaaaaa agtttctgtc attaagcttc tccaatcaaa cgaagcaagt attgcccgta
    33061 ttcgtttttc tttaaagact gcgccaattc atggacatct tctttactga tgtaacccat
    33121 gcgataggca atttcttcca gatttgccac ttgagcgttt tgcaaacgtt gaactgtttc
    33181 aatatattga gccgcttcaa gtagactttc atgcgttcca gtgtctagcc atgcaaaacc
    33241 acgccccatc aattcaacgg agaggtcacc acgttccaag taagccttgt tgacgtctgt
    33301 aatttccaac tcaccacgcg cgcttggttt aatgttttta gcaatttcta ccacgtcatt
    33361 gtcatagaaa taaagtccag tcactgcaaa gtgggactta ggcacttctg gtttttcttc
    33421 gatagagata gcattcatgt tctcatcaaa ttccaccact ccaaagcgct cagggtcttt
    33481 cacttgataa ccaaaaacgg tggctccttt ttctttggca gctgcctttt gaagcatttt
    33541 agtgaggcca ttaccgtggt aaatattatc tcctaaaata agagcaacac ggtcatcacc
    33601 gataaactcc tctccaataa tgaaagcttg tgctaaacca tctgggcttg gttgttcctt
    33661 ataggataag ctaatgccaa attctgaccc atctcctagc aattcttcga aacgaggaag
    33721 atcttggggg gttgaaatga ttaaaatatc tttaatccct gccaacatca aggttgacaa
    33781 tgggtaataa atcattggtt tgtcataaat gggcatcaac tgtttagatg cggcacgggt
    33841 cagtggatac aagcgtgtcc ctgaacctcc tgcaagaata atacctttca tacgtagtgc
    33901 tcctattctt ctatataccc tatcattcta tcattttttg aaagcagtgt cacgctttac
    33961 cagtagaccg caaaaggtaa ggctcagggg aatagtcgct aggcgttaaa agtccttcgt
    34021 gtcctagcaa taattgagct aattcatagc caatcaaagg gccaactgtt aatcccgatg
    34081 accctaaacc actagctgta taaaggttct tcaatcctgg aacctgacca taaaaaggag
    34141 aataatcact ggtataagct cttatcccta cacgacatga tttttgagta gcttctttta
    34201 ataacggcaa ataagtgaga gcttgcattt caagtttttc taagacctgc caatcaggct
    34261 ccaaatcata acctttatca ttttcatggc tcgcaccaac agaaatctta ccttgattga
    34321 aaggaatgag gtctatttca ccttctggca taacaacggg ataattgtcg ctgatgatgt
    34381 gatgaacgtc ataatccaag agttgtccct tttgtggtcg cacatcaacc tgatagccta
    34441 aaggcatcaa taagtcaggt agccatgctc ctgctgccag aatgacctga tcaaaataat
    34501 gaccagcaat ctcataacca cttccttgct gtttcagagt gactttttgg cgaataactg
    34561 gataaccact agtcttgagt aacgtctcac ataaagcggc tccctccact ctagcagctc
    34621 ctgaagcgta cagacagtta tcaaagccaa tcaatccttt aaaatcatcc cccagttctt
    34681 tacgattttt aatggctaac tcaccaataa tcggtgattc tacctttctt gctaacgcta
    34741 attcataaag atctcttagt ttttcttcct gcttttttaa aacatagatg ccattttgct
    34801 gataaaaatc tgttgcaaaa ccatcttctt tgaggtcatt gattaattgc tgataaaagt
    34861 ccgctcctaa acgagccatg cggtaccaaa ctttattgcg acgctttgaa aaccaaggac
    34921 taataatacc agcagcagcc ttagtggctt gtccttgacc atggtcaaaa atggtaactt
    34981 ctttttgacc actttgttgt aaataataag cggcggttga tcctacaatc cccgccccaa
    35041 taatggctat tttcattcct ggtatccttt tatcttactt taagacctta acagcctata
    35101 aatggctaaa tggattggtc gaggctttgc ttgaaataat gctgacatcc caaccgttct
    35161 cttctttcca cccttggagt ttctccttta atttctccgt aaaaagcacc tcaatatgat
    35221 gccccgggtc aaccgcaaat agtccttctg tcagcatctc ctgtgctgta tggtaataga
    35281 tatcccctgt aatataaacg tctgcgcctt tttgcacagc atcctgataa aattcaccac
    35341 cacttccgcc acagatagca atctttgaaa tcaaagggtt ttccttatcg taacggataa
    35401 gtcgcacggt atctaaatca aacacccttt tgaccttact tgctaactct tctaacgctt
    35461 gttctttaac tgttccaata cgaccaatgc caaagccttc tttggtttca gacaagtaag
    35521 ttgcttcctt gatttctagc aggtcacaaa accaatcatt tagcccgcct ggtacaatgt
    35581 caatattggt atggctcaca tagacagaaa tgtcatgctt gaccaaatct agaaggatat
    35641 cacgctgagg ggatgaaacc agatctttaa gcggtttaaa gatgggagca tgcttagtta
    35701 taatgagatc aacttcattt ttgatggctt ctgctactgt tgactctcgg atatctaaag
    35761 taatcataac cttacgaatg tctttatcca atgaacccat ttgaagacct ttaacgtctc
    35821 tttccataga taaatcaagt gggcaaaagg cttcataggc atcaattagg gttttagctt
    35881 tcatgaacaa tcacctcttt tatttgttgt atttttgtca agagaagctg acgctcttga
    35941 gttttttctt ctgggatgca ggacaaggca taagctaact tatccatttc tcgttgccac
    36001 ttctctttaa aaacgactga tttttcctga gaaaggtatg gaccaaaacg caattctgtc
    36061 gcggataagg ccttttcacc atgctcagca acgatgattt cataatattt gtcattttca
    36121 gccatgatgg tttctgcaac aattttaaaa gcgttaaccg ataaccaagc ccgtaaatca
    36181 tcctcacgat tgttgggctg taaaaccaga cgttcaatgc cctgcaattt ttccttacct
    36241 gcctctaaaa tatcagtaat caaacggcca cccatgccac aaatggtaat ggctgtcaca
    36301 tcatcagctt cttcaaaggc tgcaaggcca ttggctaagc gcacctgaat atgctcggca
    36361 aggccagact gtgtgacatt tttaagagca gattcgtagg gacccctaac cacttcgcca
    36421 gcaatggctg ctgaaatctg attagtttct accaaaaata tgggaagata ggcatgatca
    36481 ctgccaacat ctaataattt gacacctttt ggaacatagg ccgcaacttg ggctaaacgg
    36541 tttgataatt gactatccat cttgatttct ttctaaaacg taatggttct attatagcaa
    36601 aattacctcc ataaaaaaag aaaaccaaag gctaggcttt cgattttcca taagtatttt
    36661 gatagtactt acagtaagac tgaacgggac aaatctcaca ttttggtttt ttggctaaac
    36721 aatggtagcg tccaaagaaa atcaatcgat ggtgagtaat aatccaatct ttctttggaa
    36781 ttttagccat caaatctgct tcaatctgct tgacatcggc atctggtgat gaaatattga
    36841 gcctctttga gactctagcc acatgagtat caaccgcaat agctggaaca ccataaacct
    36901 ctgccaatac cacattggct gtttttcggc caacacccgg taaactttca agctctttgt
    36961 gggtttttgg cacttgaccc ttaaaatcat cacgaatagc ctgagcagtt ttaatgatat
    37021 ttttggcctt atttttatag agtccaatcg ttctcagagc attttcaaca tcagaaagtt
    37081 cagcaaaagc taagtcttct atttctggat aagactgcca tagtccagga gttaccttat
    37141 tgacggcctt atctgtcgtt tgagctgata aaatcaccgc aattaacaat tgaaaaggtg
    37201 tttcccagtc taactctccc ttagcctcag gaaacatttg accaatgatg gtcaggactt
    37261 ttgctaatct tgcttttcca attctcatga atcactccat aaattcatcg cagatagaaa
    37321 atcctctgat atcgtcactt gagaaagatc ttcgccttct ctaacacgtc tacgttcttc
    37381 tacttgtcga agattaacaa taccttcttt tcgccaatta cgtaagatag cctggatata
    37441 tttccaattt gttttgccgt tgaagacagc ttcttttaaa gcttctcgta tcaaatcagg
    37501 atctgtttta tcatcacgaa gcgttttttc aagatcttct aactcaaaag gactcaagaa
    37561 tcgtcctaat tcacgttcaa attcatcaac taatcgtttg aaatggtttg gtgtttcttg
    37621 tttgtcaatt tcagttgccg tttgactgac aaacaattga tctaacttgg ctaacacagg
    37681 actcgcatca aaaataattt caatttctcc agtaagttca attgtccgca tatctaaaag
    37741 cccttgacta gtcaaagatg aaatgatttt attaatatca gcaactgatt ttccaagcgc
    37801 atgagcaatt tgactgggcg ctaagtcgtc tcgctttgtc gtattttgaa gatagaaaaa
    37861 ctgccagacc aaaaaatcat ctgagctctt aaaaagatct ttgtaatgaa aaagcaaggc
    37921 acttgggata accaaattac ctgacttata atgttctaaa aaactcataa tccctcaatc
    37981 aaaaggctaa aatcgaatct atagccttta ctactttaaa tcccctaatc agatgctgat
    38041 taatgtgctt acccaggaaa ctgcattaag actttatagt catagttcct aatagcatga
    38101 cgaccattta aaccttctaa ttcaataagg aaggcacaac cagctacaat accaccaagt
    38161 ttttcaatca tttcaatagt tgcttttacc gtaccgccag tcgctagtaa atcatcgaca
    38221 atcaaaacac gttgtccagg cttaatagca tctgcatgca tagttaaggt atcaagacca
    38281 tattcttttt cgtaatcggc agagacaaca tctcttggca gttttcctgg tttacgaacg
    38341 ggagcaaaac caattcctaa ctcaactgca acaggacaac caatgataaa accacgcgct
    38401 tcaggtccaa caaccatatc aatatcttta tcacaagcgt actgtgctat ttcacgaata
    38461 gcatagctat atgctttacc gtcagccatt aaaggtgaga tatctcgaaa cgtaatacca
    38521 gctttagggt aatctttgat cgatgcaatg taatttgtta aatccatagt taattctttc
    38581 tagtggcaaa ttgccaaata taaaatactc ttcattatat cacgaaacat atttttcgta
    38641 aaataagact tctgacatta tgtttatctg atacttcatt cgtaactacc tcaataacta
    38701 ctgtcaactg ctttacttat tgatcgtttg atttcaccaa ataatcatac atctctttcg
    38761 ggctagccaa agccatgatt tcttgaaatt tcaccaattc ttttaagtct tggtaaatgt
    38821 ggctctctga aatctctcgt ttttgcgctt gggggttaac cgtcatcagc ccatcgtcaa
    38881 tcgtcacaaa agacaactct tcaaaaattt gaatcaactt aatcagtaaa agtttttcta
    38941 tgtttaaata gtgactcaac tctgtcaatt tatgccgtaa atcaaattca ggaaactgat
    39001 agatggtttt gtagagcttg gcaaactgct ctctgctgcc aaatcctgtt aaataataag
    39061 gatgtttcat ctgattttta aaatagatgg cgtcaaaatc cttgtgaaca aactggttgc
    39121 gccaggtttt gaaatcttca gggatgtcat taatcagaat gactctggca tttgggtctt
    39181 cttcaatagt cggaatacct tcaggaactt tggctgtttt tgtccttaag tcaagaagtt
    39241 gcactccgtc aacacgagca tctactaaca tgaattggag actcgtgttc ccattccaat
    39301 ggttgacaga taaggtaact gctaattcta aaccagtagc ttgtcggaac tcttgcagtt
    39361 gacttccttg accaaaagcc agtacgtcaa aggaagcttt gccctgactg actttaaatt
    39421 taagatggct ctggtcttgc cctatggtac gcgcttgact aacccttatg tccttgacat
    39481 aaaagaccgg cttttgatga tccatcccat aaggggctaa tttatctaaa ctctttaaaa
    39541 tatcaaggct aaggtcgtcc aaagacagtc tttcatcaat agttaacgta tttttggcag
    39601 tctgatctaa gccacgttct atcacaaact gacaaagaaa gtctgaaaga gcttccaagt
    39661 tgtcaacggg cagggtcatt cctgctgcac cagcatgtcc cccaaaggct gtaaataact
    39721 cacgcttgcc attcaaggct tcaaaaatat taatagcttc taaacttctg gccgagcctt
    39781 ttgcaaagcc attatcaatg gtcaaaacga cgaccgtttg tccaatagtt tccatgatac
    39841 gaccagcgac aatcccaaga acaccaggat gccagccagc ttgtgccaag acttgaacag
    39901 gtttttgagg atcaaccata gccatcgctt gatcaaaaat gtcttggact aaggccttac
    39961 gctcttcatt ttttttctta atcatcaagg caatcgcttg agcttcttgg tcatcaaagc
    40021 ccgtcagtag ctcaatggct ggattagggt catctaagcg ccctaaagca tttaattgcg
    40081 gagcaatctg aaagccaata gcgtcttcat taaaatgttc caaatcaata ggagacaaag
    40141 acatcaactc ctgcaagccc actctttcgg tgtgtttgag catggccaga ccatttttga
    40201 ctaaaacacg gttttcacct gtcaagctta ccatatcggc aatggttcca atagctacca
    40261 agtctagaca gtctgttggt aaactttcta gcaaagctgt tgccaattta aaggcaacgc
    40321 cacagccagc taagtgttta aagggataat cagcatcagg atgctcagga tgaatgatgg
    40381 caaaggcttc tggcaattct tcaggcaggc tatgatggtc agttacaatg acatcaactt
    40441 cctgttcttg agcatatcta atcgcttcat gtccggccac gccattatca accgtgataa
    40501 ttagggacac agcttcctgc tcaataaaat atttatagac gctctggttg gggccatagc
    40561 catctgtaaa gcggttggga agataaacca aaggctctgc tcccatcatg tctagggttt
    40621 ctttgacaat agaagccgac gtcatgccat cagcatcata gtcgccgtaa atgagaattc
    40681 gttcgccctc ttcaatagct tgacgaattc ttggcacagc ttttgccatg tcatgtagca
    40741 agtaaggatc atgcagttga gacaagtccg ctgttaaaaa ctcatctaag gcttcttcag
    40801 tccttatccc tcgctcataa atcaactgag cggcggtctg ggttagacct tttgtctttg
    40861 ctagcttaaa gaagccatca tctggcttct tgtcttttat tttccagcta tatttggatt
    40921 taatcattta taattaaata cctttcttgc aagataatca gataatttag ggaaaagggt
    40981 gtaaaattga tgggtcaccg ctaaactaaa gggcaaattc aattctcgtt tatttttccc
    41041 gataatagaa accaaacgct tagccacttg atttggttgg agagtaaatg taccaacgct
    41101 ttccgaataa tgtccagacg ggtcagcttg gtcaaaaaac ttggtggcaa tgggacctgg
    41161 attcacggtg gtcacgtaaa cccctttatc cgctaattct aagcgaaggg cattggaaaa
    41221 tccgataagg gcaaacttgg tggctgaata aatgctcgat ttggctgacg caatcaagcc
    41281 tgccatggac acaatattaa taaggtgacc ttgcccctgc tctgccattt tctgaccaat
    41341 caagcaagca aagtgaatgc tcgctagggt gttaacctga aacatatcag ctatttcttg
    41401 ggcagaaaac tcttcaaagc ctttgaaagc tccgtagcca gcattattaa tcaagacatc
    41461 aatacggcca tagcgctggt aaatctgggc gaccattttc tcaatggcta ctggattggt
    41521 aatatccaac tcaaggcatt ctttgttgtc aatatgctga taacagtgtt ctaggcgttc
    41581 tttgttacgt cctaataaaa tcaagctgtc ttccttgggt aactgcttaa caattgcctg
    41641 agccagtcct ccagaagctc ccgtgataac aatgattctt tgtgccatta aataatcact
    41701 tcctctaaat cttgtaccat tttaacattt tcaaatatag tggcggcatc tttttccatc
    41761 tggcgacaat cacgccctaa aaagcgagct gatacatgat tgagcaagag gcgttttgcg
    41821 cctgcttcat gagcgatttg tgctgcctgc atgttggtag aatgcccgtg atttctcgca
    41881 atccgctcgt cacccttacc ataggtggat tcatgaacca aaacatctgc atctttagcg
    41941 agtttaacac tggcagacgt tttgcgcgta tcgccgataa tggtgatgat tttgcctttt
    42001 ttaggggcag aaatataatc tttggcacaa atcaggcggc cgtcttccaa ctcaacatct
    42061 tgaccatttt taattttgcc aaagagtggt ccgaagggaa cacccgctgc ttttaaggct
    42121 tctgcgtcta gggttccttc taagtctttt tgaactactc gataacccat gcaaaaaatg
    42181 gtatgcgcca gacgctctgc atagaccaca aacttatctg tttccattat tttacctaat
    42241 gatttgtcat caaattcatg aaaatgaatc tgataaggta cacgcgctcc agaaactttt
    42301 agactagtta acacgtaagt tttaatgcca attggtccat aaatatcaag atctgtctgt
    42361 tcttcactag cttgaaaaga ccgacttgat aaaaatcctg gtaatccaaa aatgtggtcc
    42421 ccatgcaaat gagtaatgaa aatctttctt atttttcgtg gcttaatcgt cgtttctaaa
    42481 atttgtcttt gcgttccttc accgcaatca aacatccaga cttcattgat ttcgtctagt
    42541 aatttcaagg caagacttga cacattgcgc tgcttggctg gttgaccagc tccagttcct
    42601 aaaaattgta attccattca atctattctt tctattgggt gatgtaaatc ataaattctc
    42661 gttgggcaaa atcataatac ttttgaccag aaaatgtttg gctaagagcc cataactcct
    42721 ctacattaaa ccccttaagc atggtgatac cgtttgccag acggtaaatc ttcgacaaga
    42781 gtgtgtcatc aggcgtaatg tcttcacatt ctccttgctc aaactgctta gcctgcattt
    42841 taagctggcc tttgtcttca taaaccatat attgtgggaa aatttgtgtt aattcaaaga
    42901 agagttcggg tttcttaggc tctgcttttt cagaaaatac caatgcaact tcttggtcat
    42961 tttggtaagc aaaaccataa gcttttccag acaaattgag gcgtacaaag ggcttttctt
    43021 cctcaaaaga tggttggtca gtaaaaagcc ccaaagcctt agaaagatta aaataataat
    43081 cagtcgcagc ttgcggtgac tgtttctggt agatttcagc aaagtaggca ttaataacac
    43141 ttggtggtgg tgtgataaaa gctagttttt gctggtctgt caaactggct aatagatggt
    43201 ttaggtagtt ggtatccaga ctagtaaatc caccataggt ttttgctaaa tcaatataat
    43261 tattcataaa aatcgtcaag tctccattgc tgttttgggg aaatgtagcc cgaaatatcc
    43321 tctatttctt ggtcaaacgt gtagtggtct aaaagagcaa ctcggttcaa atcatacagc
    43381 ttgtacgcct tgtcttgatg cactttgatt ctaaaaggaa caaactggtc tcgaatttgg
    43441 tcaatgatta aacgtctcaa gagaattttg ctatcctttg aacgggctga aatcctaata
    43501 tttggaaaag cagtagctgt gaattgttct gctatatcca ccttgttata aatagctaaa
    43561 cgtggaatat taagcatgtc tagctctttt agaaggttta aaaccacttt ttcttgctca
    43621 ctatgattag ggtcgctagc gtcaatcaca tgtaacagca aatccacata tttgctttct
    43681 tctagggttg atttaaaagc agccactaat tccgttggca agtcttgaat aaagcctacg
    43741 gtgtctgtta aggttgcttg aaattgattt tctaaataga gttgctttgt agttgcatct
    43801 aaggtagcaa ataattcatt ggcttcatag tggctgtcat ctgtcaacaa gttcataatg
    43861 gttgacttgc cagcattggt gtagccaatc aagccaattt taaaggtatc tgaacccaca
    43921 cgacgatctc taattgtttg acgatttttc tctacctgag ttaattggcg ttcaatatca
    43981 gcaatctgat gacgaatcga acggcgattt aactctagtt ggctttcacc tggtccacgg
    44041 ctcccaatac cacctgcttg acgacttaac atgatgccct gtccaaccaa acgaggtaac
    44101 atatatttca attgggcaag gtgtacttgt aatttgccct catggcttct ggcacgcatg
    44161 gcaaaaatat ctaagattaa ctgcatacgg tcaatgactt ttacctctaa aacagcttct
    44221 agattagcat tttgcctagc agtcaaccga ttgttcacaa taactgcatc aatctcatca
    44281 gcttccacaa tcgccttaat ctcatccagt ttccctgagc cgataaaggt tttgctgtcg
    44341 taacgttctc gtttttggct gaaacttgcc ataactttga cgccagctgt tttggcaaga
    44401 ttagctaatt ctgtcatgga catatcaaaa tgttctgttg tctgaagctc aactcctaaa
    44461 agaatcactc tttcttgctg acgctttgtc tcaatcatca cctttaccaa tcctccaaat
    44521 tccgtaaatt ctattataac atatcttcaa cagattctgc taattttgcg tcatgacttc
    44581 tctttctgac caagaaaatc cctgacccta tcatgtacta cctgtgggta atcaggagcc
    44641 gttatggcag tgaagctaac agccattcga ttgcggaacc aagttagctg tcgcttggca
    44701 aaacgtctcg tgttttgttt taactgatca ctagcttctg ccaaagtcat ttcacctaca
    44761 aaatagggga ataattcctt ataacctatg ccacgactag cctgaacagt cgggtaatgc
    44821 tcatataacc attttgcttc ttccaataag ccgttttcaa gcatacgatc cacgcgctga
    44881 ttgatacggt catagatgac ttggcggtca tcattcaagc cgataataag cggctcataa
    44941 gccgtctcgg cattctctaa ttcatcagca aactgagcca attcaagggc tcggatcgcc
    45001 cgcctgcgat tcacctgctc aatggtaatg ttattgactt gcaagcgttc atacaagtcg
    45061 tgatcgtcca attgctccaa ctcattccga taggctttta ccgcctcttg atcaacttga
    45121 cctcctagat gataaccttc gagtaaactt tgtaagtaaa gaccagttcc acctacaata
    45181 attggtaatt tcccacgact aacaatgtct gaaatagctt tttgagcatc ttgaacaaaa
    45241 tcgtaggccg aataagactc cgtcacctca cgaatatcag ttaagtgatg aaccgctgct
    45301 tcttgctctt cttgagtggc cttggctgtt ccaatatcca actgtcgata aacttgctgg
    45361 ctatctcctg aaataatttc tccattaaaa gccttggcta aactaatccc aagtgctgtt
    45421 tttccaaccg ctgtcggacc aacaatcaca actattttta tttttgtcat tttcttgtct
    45481 ttctattaga aaagcgtgtc caaaaacgcc ttttacttga aaattagctt atttttcgct
    45541 accatatatt ataacataag attaaggacc actgaggtcc ttcactagaa atggagaata
    45601 atcatggaat atcaatttgt taaaggtctt gctactggcg tcctagcaac tgctgctact
    45661 gttgctggtg ctgtctttgc tgtaaaaaaa acaatcattg accctgaaga agaaaaagct
    45721 gctttcattg aagaaaaccg caaaaaagct gcgcgtcgtc gtgtagctcg ctaacgtgac
    45781 aatggatcaa tttaaaagag actagcacat taaagtgccg gcctcttttt tagtaatctc
    45841 gataactagt tagtagtaac tgtctcttga tgagccaaga tgttagctgc tttacttatt
    45901 ttgaaataga aatctcaggt aagccccata aacatacgtg actaaagctg tcgccaacaa
    45961 tacctctcct agcaaaagaa cctgccaacc taaaccttgc caacctaaaa aagataaggt
    46021 catttttaag gaagtggcac taatcacaaa cggaaaggta aaagctgaaa aacctgggtt
    46081 aaagggacga ttgagtaagc gaggaagctg tacaaccaca aaagcatata acagttgtga
    46141 gctgatgaga agaaagataa ccattcctac ttgtggtcta ggaaaggttg ctaaataaga
    46201 cgctgaaagt aaggacagag gggcacaaaa cgttgaaata ttgggcatta ctgcttgacc
    46261 taaaccaatc ccataagtct ttttggccat aaaaggtaaa atcacagcag ttaagagaag
    46321 acaaacccaa aaaatcacct gtcctaataa aaactgccta ctagcaggtg ctgttaatgc
    46381 cgccattgca attccaacaa aaagcacgga ccaggaagga aaaacgttat cccatgaaaa
    46441 agaaaagaca aaacgatact ggtaataagc aatcaggaca agatttccca aaaagaatag
    46501 ccaccaagtg agaaagccta accaacaccc tcctgtcact ttgagaaaga gtgaagacaa
    46561 caacatccct gtcataaaaa aagttggaaa aacagaggca attagaggtt gtcgtaactg
    46621 cattttggta tcgttaaggt tcctaaccat gccaacaagc aagataccat aaataaaaag
    46681 agctgccaga attcccaaat aactaaaaat cgaaacataa gtagccaaca aattgccaaa
    46741 tgacaacgtt cctaatgcca atcctgacat gaccaatggt gggtttttaa ggtgtttcat
    46801 aagtgtcctt ttctgcctat taacagctat ttttagtgac ataatcttgt ttattttatc
    46861 acatttcgag catttttgcc ataaaggctg ccagatgcgg ataattctcg taagattttg
    46921 gtgttttttg agaccatagc gccatggcgt aagcataagc atctgcaatg gtttgttgat
    46981 ctcgataaac atgcccacta tccccaataa gaccatctaa atgcgtcata gcaatatcca
    47041 tccgcttgta agaagcttgt ttgacttttt caagcgcttg attgtcttga gaaatagtgt
    47101 agcgatgagg gttgtacatt ggcctaaaaa caaggggaaa atcacctgtt aagaaatcca
    47161 tgatttcgtt gaatcgactt tctgccaaaa gattatcttg gggaatgagc tgagatttca
    47221 gggtttgttt cgctataaag agcaagataa tacctgcctg tgtgacgatt tgaccatcat
    47281 caagctgtaa agcttaaacc attcccaaag gattgatggt aaggcagtct tcagaatcca
    47341 gttttacctt ctctatctcg taatacagaa actcacaatt cttttgaaaa ggttctagac
    47401 agagttggtg ttgacgtctt cgctgttgat ggctctgcat gacaaaatga gcttggtgtc
    47461 cacgttcact agtatcttgt tgcaaagtct ttgcaatttg gtctcatcat ctgtatcaca
    47521 aaaaacaaac cagtttcctg atttgttttg agatattagg cacctacaaa ttctggcaag
    47581 gattctccaa tagcttctaa acgttctgcc catccttgac gtgataaacc attttcttgc
    47641 acatagcgat tacgttcatg tgcacgacat tcaggcgagc atcctcgaac atactttgtt
    47701 tcgttttctt ctgaagcaaa aatttgtttg ttacaaaacg gatttgcaca attgacataa
    47761 cgttcacaag gtgttccatc aaaataatct ttactaatga cagttggatt aacatgatta
    47821 attggcaccg agatacgatc atcaaaaaca tacatcgcac catcccaaag ttcaccttga
    47881 acttccggat cttttccata tgttgcaata ccaccgtgta attgtccaac atctttaaag
    47941 ccttctcgaa ccatccaacc cgagaatttc tcacagcgaa caccacccgt acagtaaaca
    48001 acaacacgtt tttccataaa cttatctttg ttgtcacgta cccattgtgg taactcacgg
    48061 aaattgcgaa tatcaggacg aattgctcca cggaagtgac ctaagtcata ttcataatca
    48121 ttacgcgtat ctaaaacaac agtatcttca tcaagcaagg cttctttaaa ttgtttagga
    48181 tttaaatact cacctgttgt ttccaaagga ttaatatcac tatcaaagtt attgtcttct
    48241 aacccaaggt gcacgatctc tttcttataa cgaacaaaca ttttacggaa agcttgttga
    48301 ttttcctcgt caatcttgaa ccaaagatca gcaaaacgct catcgctgtg gacccaatcc
    48361 atatacttct gagttgtttc ataatctcca gaaacagttc cattaatccc ctcatccgca
    48421 atcaaaatac gacctttaag cccaatagat ttacaaaatt ctagatgttt cgcagcgtac
    48481 tcttgcgcat tttcaattga aacatattta taatagagta aaactctgat tttttctgac
    48541 attttttctc cttcattgtt attcagttac ttcctattat atctaggaaa aacaagtcta
    48601 ggcaagtcat ttgtttgtct tttttttcac aaaatagatc tcaatttatt tttgatgaga
    48661 tgagatgcaa cccattactc ctttaagcag atcattagaa gctttattta gaaaatgcta
    48721 agataaaaca aggaggccaa aatgacttat gaactttgtt tagaatatgg gacttatccg
    48781 ttgtcacgtg tttatgctta ttggggagaa gatcaaaatc ccccaacatt cattcaagaa
    48841 gatcgactgc tttgccataa actagaaact atgaatcacc tgttccatga tttatttgta
    48901 actattgaat cacaattcca ttatgttggt tttaacatgc ctgaaaaaag agcgcagatt
    48961 cggatactat atcaagaagt agctactata ttaaaatcca aatataagga ttatccaatt
    49021 aagattgaga cgtttcttct ttaaaaatct aatactaaaa aactaactgt gcttagacag
    49081 atgacacagc tagtttttta ggtaaaactc ttcttaaatt ttaaaacgtt tcgaaaaatc
    49141 actaaatgct ttaatagcac ttgctaaaaa tggtttcacc atctcatcaa taattaacct
    49201 tgattactta caatcttatg aatctgagtc aaataaaatt caggctgtgg cattacagag
    49261 atatttaaaa cctatactca tcgttttcaa ggtcagaaaa ataatgattt tgaaaaggtt
    49321 cgtcaactct tctagataat tttggacaaa ttttggaaaa gaaacaaaaa aagcctatca
    49381 aatagggctt ttttatatga tttctatcca ccttgaggga atcgaacccc catctcaaga
    49441 accggaatct tacgtgatat ccattacact aaaggtggtc acaactttgt caataccctt
    49501 atagtatatc ataaaatgaa ataatatgaa ataacttttc taaccagaag acaataaaaa
    49561 gttgaggaaa acctcaactt tttagattta ttacaattca atatcaccga aaagatcagc
    49621 cattgagaat ccagtttgtg tttctgggag ttcgtagtca cgtcttgatt cacgttttgg
    49681 acgacgtggg cgtgattgac gtttttcttc tttgttgtct ccttcagctt gcgctgggcg
    49741 ttcttcaaga gctttgattg ataatgatac gcgctcatca gctgcattca cttcaagaac
    49801 tttaactgtt acttcttgtc ctacagaaag tacatctttt ggattttcaa cacgtttgtg
    49861 tgaaatttgt gaaatatgaa caagtccatc aatacctggt aatacttcaa caaaagcacc
    49921 gaagtcagtc aagcgtttta ctttaccttc aacaacatca ccttgagcaa gtttttgttc
    49981 aacgccgtcc catggtccag gtgttgttgc tttaagtgaa agtgacacac gaccagcttc
    50041 ttcgtcaatt gaaagaactt taacttcaac ttcttcacca actgaaacaa ctgatttagg
    50101 tgacacatta cgttcgtgag acaattcagt cacgtgaaca agtccgtcaa caccaccaag
    50161 gtcaatgaaa gcaccaaaac ttgttaaacg cgctacagta cctgtaacga ctgcaccttc
    50221 tgaaatctta gagaacactt cagcacgagc ttctttagcg gcctcttcga taacttcacg
    50281 acgtgatagg atgaaacggt tttctgctgc atcaacttct ttgattttag catcaaactc
    50341 ttgtccaaca aatttttcag tgttgcgaac aaaacgagtg tcaatcattg aagcagggat
    50401 aaatccacga agtccttcaa attcaactga aagaccacct ttaacagcac gggtaccttt
    50461 aacagtaaca acttcgcctt cacgaccaac aagtttgtcc caggctttac gagcttccaa
    50521 acgtttttta gatactagga aagtaactgt atcagtatct ttacctacta cttgacgaag
    50581 aacaagtact tcaactgtgt cgccagcttt aacaaagtcg ttaatatcag catcgcggtc
    50641 gttagtcaat tcacgaagtg tcaagacacc ttcaacacct gttccttcga taacaacgtt
    50701 tgcttgaccg ttatcaacag ttaaaacttc cgcagtgaca acatcaccag ggttcacttc
    50761 gctaacactg tttagcaaat cttcaaattc attcattcta aaaaatcctc caacaaaagc
    50821 tagccaatgc tagcttttga taacaatata ttttctcaag gtaacccgca acgacaacaa
    50881 ctcttatctt tgacggtctc agggagcacc tgatacctct gactggggta gctggattcg
    50941 aaccaacgca tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaataaaa
    51001 ttttttacag aaaactaatt ttctaattag attagtttcc gaaatggaaa gagagggatt
    51061 cgaacccccg aacccgaagg agcggattta cagtccgccg cgtttagcct cttcgctatc
    51121 tttccgtaac aacaaaaact attctatcat agtttttgta agctggcaag tgtttttgtc
    51181 taattttaat ggttcaaatt gtagttttca atgatatttt caaccgcttg ttcgagcgtt
    51241 ttgaagaagc aatctactcc atcatttttt aagacagcaa atttctcatc aagttctgca
    51301 atttctccaa ccacacgttt accaatttgt aattgatagc catcaatctt agtttcatta
    51361 accataactt tgtgatcaat cagttggatt tcaatttttt tatctttttt actcatcact
    51421 ttacctcact ttgtctattt tacacaaaat caaaaaagct tgcaagagca agctctattt
    51481 taatctactt ttacaatcca accttctggt gcttcaatat ccccaaattg aataccgacc
    51541 aactcatcgt ataaacggcg tgtcacagga ccaacttctg tttcactgta aaagacatgt
    51601 aagttatcct tgtactggat accaccaatt ggagagataa cagctgctgt tccacaagct
    51661 cctgcttcca caaatttatc caattcatta attggaacat caccctcaat tactgtcata
    51721 ccaagtcttt cttcagctag ttgtaagagt gaatacttcg taatagatgg caagatagat
    51781 ggactaagtg gcgtaacaaa ttcattattt gcagtaatgc caaaaaagtt tgcagctccg
    51841 acttcttcaa ttttagtatg ggttgctgga tctaagtaaa tcacatcaga aaagcctgct
    51901 gatttagcgg ccttacctgg tagcaaactt cctgcatagt ttcctcccac cttagcagca
    51961 cctgttccgt aaggagcggc gcggtcaaac gcttcagaaa caataaaatt agtcggagca
    52021 agtccacctt tgaaatagtt tcctactggc atggcaaaaa tggtgaaaat atattcttcg
    52081 gctggtttaa ccccaataat atctccaact ccaattaata acggtctcag gtaaagcgtt
    52141 gcacctgttc cgtaaggtgg tacaaagtct tcattggctt taaccacttg cttagctgca
    52201 tcaataaatt gctctgttga tacttgtggc atcaacaagc ggtctgctgt ggcttgtaaa
    52261 cgcactgcat tacggtctgg tctaaatagt tgaatagagc catctttggt gcgataagcc
    52321 tttaaacctt caaaagcttg ttgcccataa tgaagcgctg gagcgctttc tgagatatgt
    52381 aaggtggcat cttctgttaa ttgaccttta tcccattgac catttttgta ataagaaatg
    52441 taacgaaatg gcaacttatg atattcaaat cctaggttgt cccaatcaat tgctattgtc
    52501 atcatcgtac ctcttttctg cttttttcta ttgtaacttt ttttcaataa ttttcaagtt
    52561 tattctactc ttttgcatta atattctaaa tttaccataa aattaaaaag agttttcact
    52621 ctttttaacg tgttctagct accagtactt cttgatccga aatagtgtct gaaataaagg
    52681 agccattgct ggttctttcc gataacgaaa gcgtttctaa agcaatctcg taggtttgac
    52741 cagtcttact aatgacttca agcatttgtt gattagtttc ttcttcaggt atatcagtga
    52801 acaaatcaaa ctgctcagct gaagtatctg attgaacgcc tccggccaga aaaactctat
    52861 gaggtttggt ttttaactct cgtaggacca atagtccacg attggcacga cttgtctgag
    52921 gaatatcatc gacagccatc cgtttgagag aacccctctg agttaagaca aagaaagagt
    52981 tacttgtcac agcaaaggct gaggcaaggc tgtcatcatt tttcaagtta atgcctttaa
    53041 caccagcaga tttcaaccct tgaataggca cttcctgact ggagaatcgc aaagcataac
    53101 catttttagt cactaatagg aggtcttcca taataactgg tgacaaggta accacgcggt
    53161 ctttgtcatc ctttagcttc acatatttgg ttgatttaga tttataagtt cgccaaggac
    53221 ttagttcttt acgatcaaag cgtttgataa aaccattttg tgtgacagcc acatacaagc
    53281 cctggtcaaa ggaagtcaca atatcagcgt agagaatctc ttcttctgtc gcgaagtttg
    53341 aaatggtttg tgataaatgt tcaccgatat ccttccaacg taaatcggtc aattcatgga
    53401 ttggccggta aatgacattg cctaaagttg taaacaacaa aaggtgttct gttgttttgg
    53461 cctgtttaac gaagatgagt tcgtcatcat ctctcttgcc aacttcttcc aaactagacg
    53521 cattgaagga tcgtgggctg gttcttttga ggtatccgcc ccgtgtcaca ctaacaaaag
    53581 tttcttcctc tgcaatcaag ctggcagtgt caatctcaat gatttgactt tctgcttgta
    53641 actctgataa acgaggattg gcgaatttct ttttcacttc tcttaattca cgtttcatga
    53701 cgttatacat ggttgcttcg tcaccgataa tagcggaaag ggtcgtgatt aagtctctta
    53761 aatcattttc ttcattttgg agagtaacaa tatcggtatt agttaaacga taaagctgca
    53821 aggttacaat cgcttctgct tgttcctcag agaaatcata gctgactttc agattttctt
    53881 tagcatcagt cttattgtca gacgatctaa tcaaagcaat aatctcatct aagatggaca
    53941 agacacgaat caatccttca acaatgtgga ggcgtttttc agctttggct ttatcgaatt
    54001 tagaccgctc aataataata tctttgcggt gactgatata gcttgatagt attttttgaa
    54061 gccctacttg acgtggtgtg aagtgatcaa tggcaaccat attgaaatta taattaactt
    54121 gaaggtctgt gtatttcaac aaataattta gaatggtttg gctatctgca tcttttttca
    54181 actcaatagc tatgcgaaga cctgtgcgat cagattcatc acgtacttct acgatgcctg
    54241 ggactttatt gttaacacga acatcgtcaa tctttttgac caagactgct ttgttaactt
    54301 cataaggaat ctcagtgaca ataatttgtt gtttaccacc tttaagttcc tcaatttccg
    54361 tcctagagcg aacaacgaca cgtcccttac ctgtttcgta ggcttttttg atttcgtcag
    54421 ctccttggat aatgcctcct gtcgggaaat ctggcccagg caaaaattcc atcaatttct
    54481 ctaagctagc cttgggatga tcaatcatat acacaacagc atcaatcact tctgacaaat
    54541 tgtgcggtgg aatatctgtc gcatagcctg cggaaatacc agaagaccca ttgacaagta
    54601 agttaggaaa agctgctggt aaaacggtgg gttctttttc tgtgtcatca aagttccacg
    54661 caaaagagac cgtatttttt tcaatgtctt gaagaagata acctgcaatt tcagacaagc
    54721 gagcttctgt ataacgcata gccgcaggcg gatcgccatc cattgaacca ttatttccgt
    54781 gcatttcaac aaggatttca cggtttttcc aattttgact catccgtacc atggcatcat
    54841 aaatagagga atccccatgc gggtggaaat tccccatgat attaccaact gatttggctg
    54901 atttacggta acctttttca aaagtattgc catccttatt catcgaataa agaatccgac
    54961 gctgaacggg tttcaatcca tctcgaatat caggaagtgc ccgttcctga ataatatact
    55021 tggaataacg gccgaagcgt tctcccataa tatcctcaag ggacatgttt tgaatgtttg
    55081 acatattcaa atagctttct ttttcattat ttattaatta cctaaaaaac aatcgtcttt
    55141 agcacttgta attatctgtg agaaacttgt atgactaaaa caccgtattt tcttctaagg
    55201 taaacttgac gttatcctcg atccactgac ggcgtggggc tgctttgtca cccatcaaca
    55261 cagaaacacg tcgctctgct cttgccaagt cgtcaatagt aacacgaata agggttctgg
    55321 tttcagggtc catagtggtt tcccataatt ggttagcatt catttcaccc agtcctttat
    55381 agcgttgaag aatagctcct ttaccaaatt ccttacgtaa atcttctaat tcaccatctg
    55441 tccaagcgta ggacactttc tctgttttac ctttaccttt tgacatttta taaagcgggg
    55501 gaagcgcaat ataaacgtga cctgcttcca ccaacggtcg catataacgg taaaagaaag
    55561 tcagcaaaag agtctgaata tgagccccat cggtatcagc atcggtcatg ataataatct
    55621 tatcatagtt gatatcctcg aggttaaagt cagctcccac tccagctcca atggtataaa
    55681 ccatagtgtt aatttcttca tttttcaaga tgtcagccat cttagctttt tcggtattta
    55741 aaactttgcc acgtaatggt aaaatagcct gaaatttgcg gtctcgtcct tgtttggctg
    55801 aacctcccgc agaatctcct tcgaccagat acaattcatt tttcttggca tttttggact
    55861 gggctggggt taattttccc gacaacaagc ctttgtcttt tttgtttttc ttaccattac
    55921 gtgagtcatc acgcgctttt cgagcagctt cgcgagcatc tctagcttta atggctttgc
    55981 gaactagatg agaagctact tctccatttt cgagtaaaaa gaaggttaat ttttcagaaa
    56041 caatgctctc tacaataggt ctcgctaagg gacttcccaa tttgtctttg gtctgtcctt
    56101 caaattgcaa gtgctgctca ggaactaaga tagataatac tgctgagagt ccttctcgat
    56161 aatctgagcc ctctagattt ttatcctttt cttttaagag attggtttta cgagcatagt
    56221 cattcatcgc tttggtaata gctgacttta gtcccgtttc atggcttcca ccatctttgg
    56281 tgcgcacatt gtttacaaag gataagatat tgtcggagaa accatcgtta tactgcaaag
    56341 caacctcgac ttgaaagtct tggtcttgac cttccatgta aataacaggt gtcaaggttt
    56401 ccttatcttc attgaggtat tcgacgaaat cttgaacccc attttcataa tgaaactctt
    56461 caataatcgg gtcatctcca cgaagatctg tcaagctcat cttgacattt ttcaaaagaa
    56521 aagcagattc tttcaatcgt tctgaaatgg tattgaactt aaagtcaata gttgaaaaaa
    56581 tcttatcatc tggcataaag gttacaaccg ttcctgattt agacttagga gctgtgccaa
    56641 cttttttaag ggttgtaaca ggtttccccc cattttcaaa gcgctgacga tacactgacc
    56701 cgtctcttgt gatttcgact tctaaccagg cagacaaagc attgacaaca gaggagccaa
    56761 caccgtgcaa accacctgac gttttgtagc caccctgacc aaatttacca cctgcatgaa
    56821 gaatcgtaaa aataacttga acggtgggaa tccccatggc atgctgacct gttggcattc
    56881 cacgtccgct atctgccaca ctgaccgagc catctttatt gataacaacc ttaatatcat
    56941 ctccaaaacc agacaaggcc tcatcgacag cattatcaac aatttcccaa atcaggtggt
    57001 gcaatcccgt agcatctgtt gaaccgatat acatccctgg acgcttgcga acagcatcta
    57061 acccttctag gacttggata gcatcgtcat tataattatt aattgtaatt tctttcttag
    57121 tcaacaccga cctccagaca gtttcatctt ttttatctta caagtttttt accaattttg
    57181 caaaataatt tgctaatttt ttccgaattc ttttccagat ctagttctcc aatctatgaa
    57241 tatgttataa taaggattat gaaattacta ctttttatta ccattgccta tttacttggt
    57301 tctattccaa ctggactatg gattggacag tacttttacc acatcaactt acgagagcat
    57361 ggatcaggaa atactggaac cacaaatact tttcggattt taggtgtcaa ggcaggaaca
    57421 gctaccttag ctattgatat gtttaaaggg acactttcaa tattgttacc aattattttt
    57481 ggtatgactt caatttcatc cattgctatc ggctttttcg cagttttagg gcatactttt
    57541 cctatttttg ccaactttaa aggtggtaag gccgtagcaa caagtgctgg tgtattgcta
    57601 ggctttgctc cgttatatct ctttttttta gcatctatct ttgttttagt tctctattta
    57661 tttagcatga tatctttagc tagtgtggtt tcagctatcg ttggtgtgtt atctgtttta
    57721 acatttcctg ccattcattt tcttttacca aattatgact actttttaac ttttattgtg
    57781 atattacttg cgttcattat tattataaga cacaaagata acattagtcg tatcaaacat
    57841 catactgaaa atctaatacc ttgggggcta aatttaagca aacaagtgcc taaaaaataa
    57901 atttactaaa agcctgactt cctctgaaag tcaagctttt ttgttttaac tcatttgtta
    57961 attagggtaa acaacctctc cgtctgcaat agtgtatttc acgacacctt tgagtttgtt
    58021 accaataaat ggggaattac tagctttaga agcaaaattc tcagtgatca gacgttcttg
    58081 cttgtctgca aaaataacca aatctgctgg accattttct gccaaataac ccgcatcaaa
    58141 accataaagc aaagctggat taagcgtcat tttttctaat agtgacataa gtgtaagatg
    58201 acctggttca accaaatgcg tcaaacctaa tgacaaagaa gtttcaagtc ctgtcatacc
    58261 agatggagct ttagtcatat catcaacagc tttttcatcc ttgtgatgag gagcatgatc
    58321 agtggcaatg actgttataa cacccgattt caagccttct atgacagcta agcgatctct
    58381 ttgtgtacga aggggaggat tcatcttggc gctggtacct acaatcaata agagatcttc
    58441 agttgttgaa aaatgttgtg gggacacttc agcagttacc ttagcaccca actgctgagc
    58501 aaaagccact acttgaaccg attctgcttt agataaatgt tggatatgaa catgagcttg
    58561 cctgtcataa gcaatcatga catctcttgc aatcatacta tattctgcta caccagttgc
    58621 cccacaaaaa tgaaaatgct cctcagcaat accttcatta aaaccaagaa ccccatttaa
    58681 ctgaggatct tcctcatgca aagaaatgaa agtttggttg gcattagcca aatcaaaggc
    58741 ttcttttaaa actttagaac tttctaaggg aataccatca tctgaaaagc ttactgctcc
    58801 tgcttccaac aaagctttaa aatcagtcac gtcttttcca ttaaaggctt gggtgacact
    58861 ggcattggtg taaatatgaa tcttttcttt agctgcgcta gctaatactt cctgtaaagt
    58921 ttcgacatct gaaatgacag gattggtatt agccatcatg acaaccgtag tcacaccacc
    58981 tgatgctgct gccaaggctc ccgtgtgaat atcttctttg tgcgtttgac cgggttctct
    59041 aaaatgcaca tgaatatcga ccaaacccgg agcaacaata agaccactag catcaatcac
    59101 ttgagcttct tggcattcaa tagctgaagc tatctttaca atctgtttac catcaatcaa
    59161 gacatctgcc acttgatctc tctgcgattt cgggtccata acgcgtccat ttttgatgag
    59221 taacatgctc tctccttctt ctcacttatc tgtaaaactg atagacagac ctgtctgcca
    59281 ataatactga aactttgtcc ataggctgct tacctcaaac catctgcctg ataatcacta
    59341 atgcttgtcc tattgtaacc aatctatgcc agtcatgcct tctttttcta aaatagcatt
    59401 tgttcttgaa aagggtttgc tgccaaaaaa gccacgataa gacgacaaag ggcttggatg
    59461 aggactctcg atgatgtggt gctttggatt agtaatgaag gcttttttct tccttgcata
    59521 agctccccac aaaatgaaaa ctacagggct gtctttctca ttcagcactt taataacagc
    59581 gtctgtaaat ggctcccata ttaagcctgc atgcccatta gcctggcctg ctggcactgt
    59641 taagcaagca ttcaaaagca gaaccccttg actagcccaa gtgcttaaat catgatggtc
    59701 acgaggacca atgtcatctg ctaattcttt taaaatatta ataagggatg gcggagcaga
    59761 aatctcttct ggaactgaaa atgataagcc ctgggcctgt ttggggccat gataagggtc
    59821 ttgtcctaaa atcaacactt tggtttcttc caaaggagtg acttgtaagg ctttaaagac
    59881 attttctcgt ggaggataga caagaccgga agcataggct tcatctaaaa agtgattgat
    59941 gcgaccgtag taatgctccg gcaaaaatga tttgattttc tcatgccaaa ttgaatgagc
    60001 cataagattc ctttctaatc acgtcagttt ctaagttaaa tacgatgtcc ttttctatct
    60061 agtttaccac attttaaata gaaagaccct gaaaatatga tatttccagg gttaatattc
    60121 gttttttaca ggatattaaa caagtgctag cttattttct aagaattctt ggtaacgttc
    60181 taacaaaaaa gcaataatcc aatagataaa ggctactaaa atgtacatgg acatgtagtc
    60241 ccactcccta ccaccgataa ttttggcatt ttgaaaaata tctggtacgg taatcatggc
    60301 agctagcgac gaacttttaa ccatatcaat aatgacattg cctagaggag gaactgcaat
    60361 tcgaaaggct tgaggaagaa taattttctt aaccataaga gcatatggca accctaaagc
    60421 cttagctgct tcccactgtc ccttgtcaat agcttctata gaagagcgaa aaacttcaga
    60481 aatataggca gcgctaacca tagaaaaacc aagataagcg caaagtaaag ctggcaattc
    60541 taaaccataa taaggcaacc cgaaataaag aacaaagagc accacgatca tcggcacacc
    60601 tcgcataata gagatgtagg ccctaacaag atagtgtagc agtggctgat gtgaccttcc
    60661 tagtagggca aggagcaaac caaagaccag ccccgttaaa aagctaagca acgatatgcc
    60721 aagggtataa ggtaatcccg ataatacaaa tcctaaacta tctttcatta atgggatatt
    60781 aatcatgtgg ttaggactcc tttaacatca agtattagtt aacgtctttc gtatcaatga
    60841 tgggaatttt tttgtctttg ccaaaaggtt ttgtcaaatc ttgaccagca tagtaggttt
    60901 cagatatttt cttcaagcta ccatctttta tcatgtcttt aataacagca tctatttttt
    60961 tcttgaggct atcgtctttt ttgttcataa caattccttg ttcggttggg ttgtactgag
    61021 catcgctcat tttgacattt agatttggat tttgagataa catgtaatcc acaaataatt
    61081 tttgagctgg gtaatcattt ggaatgaaat ctgttcgacc gttagccaca tcgtttagat
    61141 aaacatctcc tgtaacatta tcgtaggtca ccagttcagc tccctgtttt tgcgctactt
    61201 tcatgtactc tgttccagaa gcgccagctg ctttttttcc tttccagtcg ctaagatctt
    61261 ttttagccat gtttgagctg ccatcagcac ggacaatcat gcctcctacc ccgtatttat
    61321 aaggcgtaga gatattgtat tttttctgac gttttggggt aatgtcaaag ttgttcaaag
    61381 aaatatccac tcgaccacta tcaactgagg taaaggcttg gtcaaatcct gtttcaacaa
    61441 acttgacttt aatgttaagt cgtttaccga tttccttgac catatctact tcgtaaccta
    61501 ctaactcatt attatcgttg taaaaagaag ttggctgata ggttcctggg gtagctactt
    61561 ttaacacccc tttttctttg atagtctccc aacttgattt ttgagattta tgtggcgcac
    61621 atgctgccaa taaaaggctg gcaagtccga tagacagtaa agtaactgat ttcttcatag
    61681 taactccttt attaagataa gaatagtata acattttgat taagttgtgt tatcagtgag
    61741 cgctcaatct ctttaaaaag ttaatctata atagttaaac tgttttataa gattattatt
    61801 gaggaatctt caataatcct gctgcctcaa actgctctgc aattcctaat aataggtcct
    61861 ctctaccttt ggctgcaatt agttgaatgc ccattgggag cccttcctta gtttcgtaag
    61921 taggtaaact aatagctggc tggccagtta gattaggcag agctgtgtaa ggattaatag
    61981 ccagactctt accaaacatg gtttcgacca aattgaattg ctcttcactg ctgaaaattt
    62041 cagcttgagc caagttagcc atgagtttcg aatctgggac aagttctccg tgcttaggag
    62101 ctggtgtgtt ggttgtgaac gtcaacaaca ggtcataagt ctcatgaaaa ctagccatgg
    62161 ttgcactgta cgtatcccat ttttgaagga cctgtgagta acgccaagct gggatgtctt
    62221 tacctgattg gtaaatagcc caggtcatgg tttccatatc gtctttggtc atcggacgtc
    62281 caaaagtgtc ttcaatatca gcaaacatag cagccgtttc cacactattc ataatataat
    62341 aatgacgaat cacttctgtc atatttacag gaaactcttc caattcaact agctgatgcc
    62401 cttgttctct taaccaagtt actgcttgtc ttaaagcttt ttcagtatct aaagatactg
    62461 ggctaccatc acttaaccgt tgataaaaag caattgtcaa gggacgttgt agcgattgat
    62521 aaatactatt ttttgttaag gtggctaggg ggaaggggct ttccatttgt tccatctgta
    62581 aatagtagag tagatttcta gtatctctaa cggatttggt caaggcaaaa tgaactgagg
    62641 ctccttgcca gcttcgataa gaaccaggtc cgacaggcat gcgcccgcgg ctaggtttga
    62701 gcccaattaa gccattaaac gaggctggaa ttcgaataga accaccacca tcactagcag
    62761 ttgctagtgc actaattcct gatgacacta gagcagcagc tcccccagat gagccaccag
    62821 catttcgtgt attatcatga ggtaatgaaa ccgggccatg gagctgacta tcactaatat
    62881 ttttaaagcc aaattcaggt gtgttagaac gccctaaaat aataaatccc aagtcttcta
    62941 accttttcac gaataaatct gttttagtcg catgatgatt cttgaatagc ttagaacccg
    63001 atgttgataa gtctcccttc aattcttgtc ccaaatcttt caaaaaaatg ggaactcctg
    63061 caaaaagctt acctgaaaaa tccctttgtt tggcttcttc tagggctgct tcaaagcgtt
    63121 ctgaggtaat agcatttaag gtagggttca actttttagc cttataaata gcctgggtta
    63181 ctaattctag tggtgtggtc tgaccggtct gaacagcaat agccatagcc gtcgcatctt
    63241 gataagtcat agctactctt cctttctaag atatgaatcc taaaacattc ttttttatta
    63301 aaacacaaat aaaagaaaac caccattaaa aggttagaaa ttagaatgtg atgtgtaagg
    63361 aatgtagaca aaacaatcaa aacataacat tttgaattgg ggttaaagag attttttcat
    63421 taaaaataaa cctggctgat agttccttat tgttgccagt ttacctggtc ttctttaaat
    63481 tttttaagta aatgtaaacc atcattagta atatagcctt gcaactttgc aactgcaatt
    63541 agctcagtat aattagaaag cgtaatcaac ttgataccag cttctttaaa attctgacta
    63601 gcttttggta actcataagt gaaaatcgca acaactccca gaacgtcagc tccctcacga
    63661 ctggctgctg cggctgcatc tagtaccgaa ccacctgttg aaatcaaatc ttcaatgata
    63721 accatttttt ggcctttaag cacacgcccc tcaatctggt tgcctgctcc atgatctttt
    63781 ggcttactgc gaatataagc aaaaggaaga gtcattttat ctgctataat ggcaccgtga
    63841 ggaatacctg ctgtagctgt accagcgatg acctcaactt ctgggaaatg agccctgata
    63901 gtttccacaa acccattctc aattaaatca cgagtcttag gataagaaag ggtgacacga
    63961 ttatcagtgt aaataggtga tttaatgcca gatgcccacg taaaaggatc ttcaggcttt
    64021 aaataaacag ctttaatatc aagtaattga gttgcaattt ggcttcctag tgtcatttct
    64081 tattctcctt tttcttcttt aacagacaag tgttggtttc ctaatcttat ctgttagcct
    64141 gcccactcag cttttatggc ttggtaagca gccactgggt cttttgcctg ggtaattggt
    64201 cgccctacca caatataatc acttccaatg cgtcttgctt ggtttggagt catcactcgt
    64261 ttttgatcgc caatattact gcctttagga cgaatgccag gagttaagca agtaaatccc
    64321 gtaggcgtca ccgccttgat agcttctact tcttgtgccg aacaaaccac cccatctagc
    64381 tgagctttag ctgccccctt gctgtaatgc aaaacagact ctaaaagact cgtttgaata
    64441 ttttgatcac cacgcatttg gtcttcactg gttgaagtta gctgcgttac cgcaattaag
    64501 gtagggcctt ggcctagtcc ttctcgagct gcttttagca tctctacacc accagctgca
    64561 tgaacagttg ccatatcaat atctaattct ttaagaactg ccatagcagc acgaacagta
    64621 tttggaatat catgtaattt taaatccaaa aatacattat gccctaacga tttgatagac
    64681 cgaacaatat ctggtccttg cgcataatat aattccatac caattttcac gtatagtttt
    64741 tcttctgctg gaaataagtc taaaaatgct ttagtctcct caaatgatga aaagtctaaa
    64801 gcaataattg ggcgttcttc tttcataact tatcctttct ataatgtgtc aatatctcat
    64861 taagcaccaa aaagcctcgc taccaaagaa gcgaggctac agcaaactaa aagggaattc
    64921 ccttttttta tcttgtatac cttgtttgcc tctctggact cacttaaagg tgtctaaatt
    64981 taaactatta tagctttttt aaaacaagat gtcaaaactt tttgttattt gaacacattt
    65041 ttcctactat atcttttttt gtacacttac gtcaactcat tttatcattt ttacccaatc
    65101 atttattcaa actcacctgt gggtacctta gggctttggt aatattttat aaaagcttct
    65161 tcttcaagat taaccctctg gatatgttca tagagcacat ccggaatagg agcttcctta
    65221 agtgacaaag cactcacttt taaagatgaa aaaacatcac ttaagacccc aaaaactcga
    65281 atgcgtttat ctccaataat aatttgaaag acttctttgg actggcataa atctatcaga
    65341 tgatccactc ctttaatcca attatcgaca atatccaaag ttttgttcat caacttaaaa
    65401 gctgattctt cataccaaaa ggtagactca atcaagcgtt gctgcatatc caaggtatca
    65461 atggccgcaa caatatctcc caactcagac tgtactaaat gagctggaaa ttcccctcca
    65521 agtatagaag gagttcgttc tacaagcttc agttcatctc gaaaaagagt caaatagtgg
    65581 atactgacca ataacttttg gattaagatt tgatgactat tttgttcagt aacattcaca
    65641 cgaccaccac cctttgatta gaaaaatacc tatttgttaa tactattaat ataacacaag
    65701 aaaaataaaa gggcaatgaa attgatagat tcaactctca aaattgaatc atatttatcc
    65761 taggccatat cgagaaaaga ctccagcgct ttttcaaagt tctaaaccca tgatgacgtt
    65821 tgtgcttgcg tctttatttt ttttgagcta gactgtactt atgagaattc aacaactgca
    65881 ttatattatc aaaattgttg agtgcggctc tatgaatgaa gctgctaagc aattatttat
    65941 cacacaacca agtctatcca atgcggtcaa ggatttggaa atggagatgg gcattaccat
    66001 tttcaaccga aatcctaaag ggatcacctt gacaaaagat ggggtggaat ttttatctta
    66061 tgctcgccaa attatagagc aaacatcact gttagaagac cgctataaaa accacaatac
    66121 tggccgagag ctctttagcg tttcatctca acattatgcc ttcgtagtca atgcatttgt
    66181 ctcactcctc aagcggaccg acatgactcg gtacgaactc tttttgcgtg agacaagaac
    66241 ttgggaaatc attgatgatg tcaaaaactt tcgatctgaa attggtgttc tctttatcaa
    66301 cgactataac cgagatgtct tgaccaaatt atttgatgac aatcatttga ctgcctctcc
    66361 attatttaag gcacagcctc atatttttgt cagcaaatca aatcctctag caactaaaag
    66421 cctattaaac atggacgact tgagagattt tccttacctg agctatgacc aagggattca
    66481 caactccttt tatttttcag aagagatgat gtcccagatg ccccatagca aatcaattgt
    66541 ggtcagtgac cgtgccaccc tctttaactt aatgattggt ttagatggct acaccgttgc
    66601 cagtggtatt ctaaatagca atctaaatgg tgaccagatt gtggctatcc cgctagatgt
    66661 ccctgacgaa attgacattg tttttatcaa gcatgaaaaa gccaacttgt ccaaaatggg
    66721 ggaacgtttt atcgaatacc ttctcgaaga agtaaccttt gattaatttc tttttcaatc
    66781 gtcacactaa aaaacacggt agtaagacct gtatcggtca agttatcgtg ttttttgata
    66841 aatatcagac aatagattgt ctccaaaggc ccaactccgt tttaataatg gcattcatgt
    66901 catcaaagta aaaaggttca cgtcggtaga ttacaccaga aaaagtcgcc aaggtgataa
    66961 tgttttccaa aaaagcctgt gaagaaaaat gagtggtgcg atgcagttcc tcttcatcaa
    67021 aaggcttaat caaatgagcc agaggattac ggacagcctt ttcaaaatgt cgtaacaaaa
    67081 aaaccaagtc cttgatttcc tgaggtaagg aggtcaacgt caacatgtct gctaagcttt
    67141 tggtcgtcac attgcgagac tgcttttgag acaggtaagc cttaaaaacc tcgtgatcag
    67201 attccaacat ggcctgaaaa tgccaggtat catattggtc attctttgta tcaaaaatat
    67261 aagccttgaa gtttggaatt tctgacgtga ttagtctgag aaaaagtcgg taaagaatag
    67321 gcgacactga cctgacgaaa tcaataatag caccgttttt tactttaact tctaaatcca
    67381 aaatgtaatt ggcaatctgc tcatcttcaa gcgattggtt aagccataat gaacagtggt
    67441 actggtctcc aatgatccga ttctctgctg catgttccgc cagaaaggca aggttcaatt
    67501 ctctgcgctc ttttaacatc tctagtaaat agagggcagt tttagggata tttggcaagg
    67561 ctttagcaat tctaaaggcg tgattataag catagacatc caaaaggatg tctagtgttt
    67621 gattattagt cattggcaat taaggtttcc aaggcgacct tcatcatatc agtgaaagtg
    67681 gtttggcgct cttcagctgt agtatcttcg gttggatcat tcaagttatc tgagatcgtc
    67741 atgattccaa gggctttgac atggtgctga gcagctaaat agtaaagagc tgctgcttcc
    67801 atttcgatgg ctttaacacc caatttacca agagccatat tacgctcagg catgttagtg
    67861 taaaagacat cagaagaaag cacattccca acgtgagttg ttactcccat ttctctggcg
    67921 atatggtaag ccttgtcaag taaaccaaaa tcagcaattt gtgggaaatc aaattctggg
    67981 aagtcattac ggataatatt tgagttggtt gctgctgctt gggcaagcac caattcacgc
    68041 acatgaactt ctgggtcaat cgcacccgca gtaccaacac ggatcaatgt tttgacaccg
    68101 taatcaacga ttaattcacg agcatagata gagatcgaag gcatccccat accagttccc
    68161 atgacagaaa cgcggcgccc tttgtaagtt cctgtgtagc caaacatgtt acgcacttcg
    68221 ttaaaacaca ctgcatcttc taggaaattt tcagcgataa atttcgcgcg caaagggtct
    68281 ccaggtagaa gaattttatc agcaatatca ccttttttgg cagaaatatg gatagacatt
    68341 attaagatat taaaggcgac aaagaacaaa gtaaaaatag gaaactgacg acgcatccca
    68401 gatgctagac agtttatctt ttttacacag ttctccgccc gtattcaatt caatgaatac
    68461 agttagccct acctttcctt ttattttgta gaaggtcaga gggcggacag aaagcaactg
    68521 aaatttaggg aactaacgcc atgtgtgagc acaaaagtta gtttatctag tttccgagct
    68581 ttccgcccgt attcaattga atacaacccc attcctttca taattgatat tgaatagaag
    68641 aagagagcta aaaatcgagt tcaaataaga aaggactaac tctctttcct ttattattta
    68701 aaaattaata cgaagaaata ttcgagtcca tgcttaattt aaaccgaata cgtctctttc
    68761 ccttcgttgg ttatgttagt tagaaaagct agaatctgag ttcaacattc atggaactca
    68821 caccccgtga ttattttttg atttttttat tgcgaacaga tgtgccaaac tgacgacata
    68881 aaataacatt cctgtaataa tgctccagtt gattttgttc gtcctacaac tcagctaaaa
    68941 tagctttaac aagacctttg aaatcttctt taatatgttc agtcacttca acaacttctt
    69001 cgtggttcaa ttctgattgg aaaccagctg caaagttagt gatggctgaa atgccaagta
    69061 ctttaagtcc agaatgagca gccacaataa cttctggcac agttgacatg ccgacagcat
    69121 ctgctcctaa tactttgaaa gcacggattt ctgctggtgt ctcataagtt ggaccagtta
    69181 agcccatata aacaccatct tctagtttga tgttcatttt ttcagccact tcatgtgcct
    69241 tattgcgata aaccttagta taggcatcag acatatcagg gaagcgtgga ccaaactcgt
    69301 ccaagttttc accgattagt gggttatttc cggtcatatt gatatggtct gtgattgcca
    69361 tcaaggtacc tgggccgtag ccgataccac cagctgcatt tgtgacaaga acaccttcac
    69421 atcccagagc tttcatgaca cgaacaggga aagtcaccac ttcaagcggg tttccttcgt
    69481 aaaaatggaa acgaccttgt agggcaagta ctttacgacc agctaaatca ccgtagacta
    69541 attttccagc atggccaaca actgttgatt tgccccagtt tggaatatct gcataatcaa
    69601 taacaacagg attctctact tcttcagcaa gttcaccaag tcctgaaccc agaattaatc
    69661 caaattctgg agcttcaatt cctttagcaa ctaaaaagtc ttttgtttcg ttaattttag
    69721 tcatcaatga catctttttc tccttttacc tcaatagggt tcacaatctc gccatcctct
    69781 ttaatataag gactaggcag gggaacagga agaatatcca gtaaggtctc agaaggacgg
    69841 caaagtttta ctcctttgcg agtcacaaca ataggacgat tgatcaaaat tggatccgtc
    69901 aacatggcat taataacgtc tttctcagct actgcttgat ttgctaatcc atgagcctca
    69961 aattcaggaa cattggttcg caagagttct cgcgcagaga ttcccatcga ttgtaagagc
    70021 tcaattaaag tctcccgatt aggtggcgtc tgcaaatact caataatagt aggctcaata
    70081 cctgcatggc gaatcatggc aagaacatta cgtgaagtgc cacagtttgg attatgataa
    70141 atcgtgattt cttccattat caactaattt tcttatttta agtgaccaag gaatgactcc
    70201 ccaatcatgg ctatatcaac tccaaaattt tctgcaacag tcgctgaaat atctgcaaaa
    70261 tgcccttgtg gaataagacc atttccagta aaggatgcag agtaggcaag caatggaatg
    70321 tattcacgag tgtggtcggt gcctgcatag gttgggtcat taccatggtc agcagtgatg
    70381 agaagcaaat cgtcttcttt catatttgcg atgatttcag gtaggcgatt gtcaaattca
    70441 tgcaagcagt cgcgataacc ctctgggtca cgacgatgac caaagttggc atcaaaatca
    70501 acgaggttag taaaggagaa tcccttagta aactcaggta attgaagagt cttaataagc
    70561 gtgtcaatac catggctgtt cgacttattg tgtcccatgt cgtttgtaat acctgaacca
    70621 ttaaagatgt cattaatctt accaacggca taagttggga cacctgcgtc agccagtttg
    70681 ttcaaaacgg tatcttggaa aggagacact gcatagtcat gacggttagc cgtacgtgta
    70741 aagtttcctg gttcgcctac ataaggacgc gcaataatac ggcctaaaag ggcagggcgt
    70801 tcaagcgtga tggagcgagc atattcacaa atcttgtaaa gctcttccac aggaataatg
    70861 tcttcatggg ctgcaatttg aagcactggg tctgctgagg tgtaaacaat caactcacct
    70921 gtttccattt gacgcgaacc aaaatcatca ataaccgcag ttcctgaata gggtttatta
    70981 gcttcacgaa taattttgcg acctgagaat tcttcaatct tagttaaaat ctcttctggg
    71041 aaaccattcc agaaagtgtc aaaaggttct gtaatgttca aacccataat ttcccaatgg
    71101 cctgtcatgg tatcttttcc aagagatact tcttccaatt tggtcacgta accagtagga
    71161 ttatcttctg ttggaacagt ttttagtggt attggacgag aaatgtttcc aagtccaatt
    71221 tttgccatat ttggaaccga taagcctgct gtttctgaaa tatgaccgag ggtgtcagaa
    71281 tctgtatcag ctacaccagc attaaagaat ttgtcagcat ctggtgctgc accaataccg
    71341 acagagtcta aaacaaccaa gtgaatacga ttaaattttg acataagtct ccaatctagg
    71401 ggaggttacg gttgactccc caatacctat aaaatacatt aacactgtta tatgctaaga
    71461 ctagcttgct ttaggcactt ctaaaacagt aacgccgtct ttactagcaa caatcacctt
    71521 atcaaccata ccattaaaga gaccgtgttc cacaacacca actgttccat ctaacaggtg
    71581 accaaaagca acaggatctt taatacaacc caaatcaaga tcaataatat agttttgcat
    71641 gtctgtcacc aaacgactat cacctttcat acgaaaagac ggtttgtaac cagctttttc
    71701 aaagacacgg aacaaacgat cagcaccata ttgaacgact tcgactggta acttaaaggc
    71761 acccagatgt tctaccattt tagaagcatc aacaacccag atgtattctt ttgttggtgt
    71821 tgcaacaatt ttttccatta gtaaggctgc gccgccaccc ttgattccat tgaaatcctt
    71881 atccacttca tcagcaccat ctacggtgag gtcaatgcta tcaatatcat ctatcgattt
    71941 taaaggaatg cctaagactt ctgcttgctt gctagtcaca cttgacgtag tcacaccaac
    72001 cacttgcagt ccttcttgct ttacgcgacg gccaatttcc tcaacaaaat agtaagccgt
    72061 tgacccagtt ccaagcccaa tggtcatgcc atcagtcaca tattgcgcag cggtaacacc
    72121 ggcaattttt ttgagtgctt ccatgattcc cccttataat agaattgcgt cttagcactt
    72181 tattatacca tgaaagcgcc aacttgttaa tgaaaacatt tgtttttctc tcattgacag
    72241 cctaagtgct atagaatagg atgatctttt taaaacttat gatttattct aaagtcatca
    72301 tataagcact tacttttcgt gtttatttag ctttttgaaa atcaagtgtt tttgtttgac
    72361 ctttactgac cttttggtta taataatact ataagatgag taaaaataat gtctgaatca
    72421 ttttattagc aaagggtttc ctatcatgtg aaatcctaac aacgattctg cgactgctta
    72481 caaacatctt atagtctatt ttttattgcg aggtaactga tatgacacat ttttctggta
    72541 aagatccttt tgtaaatatg gatgatattt tcaaccaatt aatggcaaac atgggtggtt
    72601 atcgtagcga aaatccccgc tatctcgtta acggtcgcga aataactccc gaagaattcc
    72661 aacactatcg tcaaacagga caactccctg tagcgacaac caaagcaaca acttctcaaa
    72721 tgttaacacc taaagctgat agtgtattga ctcaactcgg aactaactta acacaagaag
    72781 ctcgtcaagg gcatcttgac cccgtcattg gtcgtaacaa agaaattcaa gataccgctg
    72841 aaatcttggc acgacgaact aaaaataatc ctgtccttgt cggagatgct ggtgtcggta
    72901 aaactgcagt cattgaaggt ttagctcaag ccattgttaa tggagatgtc ccagctgcta
    72961 ttaaaaacaa ggaaatcgta tcaattgata tttctagtct tgaagctggt acacagtatc
    73021 gtggttcctt tgaagagacc attcaaaact tgattcaaga agtaaaagaa gctgggaata
    73081 tcatcttatt ttttgatgaa attcatcaaa tagttggtgc tggtgccaca agcagtgatt
    73141 caggctcaaa gggacttgca gatattctta aaccagcctt gtcacgagga gaattaacac
    73201 tgattggtgc tactactcaa gacgaatacc gcaatactat tttaaaaaat gctgcactcg
    73261 ctcgtcgctt taatgaagtt aaagtgaatg caccatcagc tgaagatact tttcacattt
    73321 taatgggtat tcgtaatctt tatgaacaac accaccatat tacccttcct gataatgttc
    73381 taaaagctgc tgttgattat tctattcaat acatcccaca gcgtagcctg ccagataaag
    73441 caattgactt actggatatg acagctgctc atttagctgc gcaacacccg gtcactgact
    73501 taaaaacact cgaaactgaa atagctaaac aaaaagagag gcaagaaaaa gctgtcgcca
    73561 aagaagactt tgaaaaagct ttagcagcaa aaacacggat tgaaacatta caaaagcaaa
    73621 ttgagcaaca taaccaaagc caaaatgtta ctgctacagt caatgatatc gcagagtctg
    73681 tagagcgctt aactggtatt cccgtctcta acatggggac taatgattta gaaaggctca
    73741 aaggaattag cagccgctta aaaagccatg tcatcggaca agatgaggct gttgcagcag
    73801 tagcacgtgc tattcgacga aatcgagcag gttttgatga tggtaaccgt ccaataggtt
    73861 ctttcctttt tgtgggtcca actggtgttg gtaaaacaga gttagctaaa caattagcac
    73921 ttgatttatt tggttccaaa gatgctatta ttcgacttga tatgtccgaa tataacgatc
    73981 gcactgctgt gtcaaaattg attgggacaa cggctggtta tgttggctac gatgataata
    74041 ataataccct aactgagcgt gttcgtcgta acccttatgc tattgtctta ctagatgaaa
    74101 ttgaaaaagc tgatcctcaa atcattacac ttcttctaca agtgttagat gatggacgat
    74161 tgacagatgg acaaggaaat actattaact ttaaaaatac cgttattatt gctacatcaa
    74221 atgccggttt tggccaacaa gatacggaaa cttctgggtt taacattatg gatcgcattg
    74281 caccttattt cagaccagag tttttgaacc gttttaatag tatcattaaa tttaatcatc
    74341 tgcaaaaaga aaatttagaa gaaattgttg atttaatgct agctgaagta aatcaaacca
    74401 ccgcaaaaaa aggtattagt ttaacgattg ctgatgacgc taaagctcat ttgatagatt
    74461 tagggtacaa tcacgctatg ggagctcgtc cattacgacg tattatcgaa caggaaattc
    74521 gtgaccgtat aactgattat tatcttgacc atccagaagt caaaaaactt caggcaatcc
    74581 tagaagaagg acaactagtg attaggcaaa aagatcagta ataaacttct tcaattgaat
    74641 aattttcaaa acatgaaaaa atccgtcttg tgactacgtt atacacttga cggacttttt
    74701 tttagcgctt ttttaaaaat aattttttca tcgcctaata actcaagttt ctttccaaat
    74761 ctggtgtaat caaaataacc attaggtgtg agcaatcctt ttgaaaaaga agtatgtccc
    74821 gctgctactt cttctttgat atcaatcaaa tatattaaat ttgtttatta aataggaaga
    74881 aaaagacggt catcagaccg ccttttattt tagttttacc tcattttctt ttgcgtattt
    74941 tgttaatttg atagcgttgt tgtatgacat acgcccgaca tctgtaacgc cgtttgcgta
    75001 atttgataac gtctgttcag atattcctgt tgctttagaa atctgataac gtgaattatt
    75061 cgttagtaag tttaaaattt cttgttttga taatacttca atcatattac ttccctttaa
    75121 tcatcttttg ctatccatag atatactaag aatacaaaag caaaaataat aaaatacttc
    75181 ataattttaa ccagttatga tatactcaac atagtaggtg tgggagcttt cgctcccgtt
    75241 cccactacag aaccttattt aaacttcctt ggttgggctg ttttttgagg ttcttttttt
    75301 gttgctttga ttactttggc tacgcccgtt aaggctgaac caaaacctgt taaagcaatt
    75361 ccgattgaac tgataagctc aattatttct gaggttttca taactttttt cctttctgta
    75421 gtttccttgt ctaaggtttt atttttttac ctccctcaac cttacatata tattatacta
    75481 ctatttatag tagtagttaa cactttttat aaactttttt gatatttttt aaattttttg
    75541 gtccgtttta acggactttt tttagttttg tggctataac agcaataaaa aagctccc
//
LOCUS       DATWEK010000006        70683 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.006, whole genome shotgun sequence.
ACCESSION   DATWEK010000006 DATWEK010000000
VERSION     DATWEK010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 70683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70683
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.006"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..322
                     /locus_tag="VCR92_000486"
     CDS             <1..322
                     /locus_tag="VCR92_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEP4267577.1"
                     /translation="SIKTKKISAVLEKVGLSSGYLNQKIYELSGGQAQRVAIARMLMK
                     PRKIILADEPTGALDGEIGKEIINLLLSETAENKYVIIATHDPAVYNKVDFIIDMKDI
                     GSKK"
     gene            319..810
                     /locus_tag="VCR92_000487"
     CDS             319..810
                     /locus_tag="VCR92_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267578.1"
                     /translation="MKKKIYIGLIVIVGVFVVFLSGKQITQKETSNKPVVTLTVYTIS
                     SSDTQKWSKVKQFETKEAIYLVKVKETTSSEEVFSNIIADGMAVGFGVSEEDVKQFND
                     NLCSPVEDAKNNKLIGIEFINFSSVDKGFVVANFDYGKKAFNSQKTENKKLYKKLYEA
                     YKG"
     gene            1014..1544
                     /locus_tag="VCR92_000488"
     CDS             1014..1544
                     /locus_tag="VCR92_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEP4267579.1"
                     /translation="MGIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNEKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDAQLAS
                     KDEQMRVKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEANQARLQVEEVQ
                     AEVGPKKGFLTRLFAK"
     gene            1593..2180
                     /locus_tag="VCR92_000489"
     CDS             1593..2180
                     /locus_tag="VCR92_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEP4267580.1"
                     /translation="MKHLDTYIAFDLEFNTVNDVSHVIQVSAVKYDHHKEVDSFDTYV
                     YTDVPLQSFINGLTGITSDKIAAAPKVEEVMAAFKNFVGELPLIGYNAQKSDLPILAE
                     NGLDLRDQYQIDLFDEAYDRRSADLNGIANLRLQTVATFLGIKGRGHNSLEDARMTAA
                     IYKSFLETDTNKAYLSQQEEVTTDNPFAALGDFFD"
     gene            2333..3061
                     /locus_tag="VCR92_000490"
     CDS             2333..3061
                     /locus_tag="VCR92_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEP4267581.1"
                     /translation="MSQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTEGGRRLYT
                     DSDLEQLRMICFLRDLGFSIEQIRKVLAEENAAQVLELLLVDHIATAKEDLAAKEQQV
                     DIAVKILDRLRKQDPQSLDFLMDISLSMKNQKAWKKRFITLIVCLTVETLLFVGGAYF
                     LQLTVWKYLLIPVFLLVLLGTLYWYYQNICYLCPSCHQTFEAKWTEFALAGHTPRTRK
                     LTCSHCHQKSYCLELAKEDTVSRG"
     gene            complement(3118..3417)
                     /locus_tag="VCR92_000491"
     CDS             complement(3118..3417)
                     /locus_tag="VCR92_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEP4267582.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQDLVTATFT
                     GDKKLVGIDFKEAVVDPEDVETLQDMTTQAINDALTQIDEATKKTLGAFAGKLPF"
     gene            complement(3610..3984)
                     /locus_tag="VCR92_000492"
     CDS             complement(3610..3984)
                     /locus_tag="VCR92_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4267583.1"
                     /translation="MSAKKTFFASNLKYLRLKKNMEQLELANLLGRKSSSSISEWEKG
                     KYTPKSGLLSDIAAIFDVSLTALMEEDLTLESKGVSYQLPQRELAMISEQLSENNYTK
                     WVDFAQILLEQQAKEDRELDNH"
     gene            4154..4375
                     /locus_tag="VCR92_000493"
     CDS             4154..4375
                     /locus_tag="VCR92_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4267584.1"
                     /translation="MTKSTLKELRTTKKMTQQELSHLTGISVRTIARYEKDTKKLRRA
                     KYEKLKGIAQALAVSVDDIFLGIDSEFMN"
     gene            complement(4455..6737)
                     /locus_tag="VCR92_000494"
     CDS             complement(4455..6737)
                     /locus_tag="VCR92_000494"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEP4267585.1"
                     /translation="MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKI
                     FFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADA
                     FLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL
                     ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINE
                     VANDKKLYRMEKELVVKKRRQITVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLND
                     YFLARGFANIYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHSKTHQV
                     RADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLAGDYLRHNDHYQELLNQQSQALDRQSGDYNQFWHDRNY
                     LKNAHQIKCDVVYSHGLQDWNVKPRQVYEIFNALPSTINKHLFLHQGEHVYMHNWQSI
                     DFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELDLGQELL
                     LIDNHYGEDEFKAYGKDFRASKAALFKGKANQALIDILLEEDLPINGEIVLQLKVKSS
                     ENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKG
                     FMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKGDTLRVILYTTDFEHTVRDNS
                     NYALTIDLSQSQLIVPIASN"
     gene            complement(6759..7418)
                     /locus_tag="VCR92_000495"
     CDS             complement(6759..7418)
                     /locus_tag="VCR92_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEP4267586.1"
                     /translation="MNHHILQRYIDNHNFPIIEKSYHKYLTFESLEEDFTYILKDGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMGEPYNVRIESEKASFYKVRRSAFL
                     KDINEDIELQGYVKDFYHNRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGEELPNG
                     QILINFVITNEELGKFCGISTASSVSRILKQLKEKNIIRIDKQHIIITNLDKLKDNIV
                     F"
     gene            7584..8780
                     /locus_tag="VCR92_000496"
     CDS             7584..8780
                     /locus_tag="VCR92_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP4267587.1"
                     /translation="MEEKLFNKHFVAITVINFIVYMVYYLFTVIIAFVATRELGAQTS
                     QAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMMYL
                     VRFLNGFGYGVVSTATNTIVTAYIPARKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMVIVLCSVLIGCVVVGAFAFPVKNMSLNAEQLAKTKSWTVDSFIEKKALFITA
                     IAFLMGIAYASVLGFQKLYTSEIHLTTVGAYFFVVYALIITITRPAMGRLMDAKGDKW
                     VLYPSYLFLAMGLFLLGSVSSGGSYLLSGALIGFGYGTFMSCGQAASIQGVDEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDLALGSGVASFRHLFWLAAVIPLICTLLYLLKTK
                     TRQVLS"
     gene            9282..10130
                     /locus_tag="VCR92_000497"
     CDS             9282..10130
                     /locus_tag="VCR92_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEP4267588.1"
                     /translation="MEMTWTVKYITEFIATAFLIILGNGAVANVDLKGTKGHNSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTVGLAVSGLFPWAHVLQYVVAQLLGAIFGQ
                     LVVVMVYKPYFMKTENPNHVLGSFSTISSLDNGQKDSHKVSYINGFLNEFVGSFVLFF
                     GALALTKNYFGVELVGKLIEAGYDQTTAATQISPYVTGSLAVAHIGIGFLVMVLVTSL
                     GGPTGPALNPARDFGPRLLHHFLPKSVLGQAKGDSKWWYAWVPVVAPILAAIVAVAAF
                     KYLYIR"
     gene            complement(10466..11362)
                     /locus_tag="VCR92_000498"
     CDS             complement(10466..11362)
                     /locus_tag="VCR92_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEP4267589.1"
                     /translation="MNEMLILRLIQALLVSAMLFIFFMLVKHLKKNKINPFKRFWTGF
                     WIGLLTDALDTLGIGSFATTTTCFKLTKLVTDDRQLPGTMTVAHVLPVLIQSLCFIFV
                     VKVEVLTLLAMAAAAFIGAYLGTHITKNWHAPTVQRILGSLLIIAAIIMIIRIIYHPG
                     EHLSDTIHGLHGIWLFVGIGFNFIVGVLMTMGLGNYAPELIFFSLMGLSPTVAMPVMM
                     LDAAMIMTASSSQFIKANRVSWDGFAGIVSGGIIGVLLAVFFLTNLDINSLKLLVIAI
                     VFFTGGMLIRSSFTSHKQQTNR"
     gene            11660..12412
                     /locus_tag="VCR92_000499"
     CDS             11660..12412
                     /locus_tag="VCR92_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEP4267590.1"
                     /translation="MTLMENITFKTPVLRVNDRDLNIAFYQNNLGLRLVSEENAIAIF
                     SSWGEGQECFVIEESPSVRTRAVEGPKKVNTIVIKTNQPKEIEQLLAHGAHYDALFKG
                     QNGYAFETISPEGDRFLLHAEQDIKHLQGTDLPSLEKDATFKGLTQFKFDIIVLNVIS
                     EERSKAFYRDLFSDQLPITMDFIQEEGPDLAIDPHIAWDLEILEFQVSKDYDMKVLKA
                     TLEEDGHKVYIDKKHKVLVLSDPSQIEVWFTK"
     gene            12397..13347
                     /locus_tag="VCR92_000500"
     CDS             12397..13347
                     /locus_tag="VCR92_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEP4267591.1"
                     /translation="MVYEMTLAVIKCIENHLHKKVYKGASLALFQSGRWQEYHIGTID
                     GRRPVDANLVYDLASVSKVVGVATICNILLNNGTLALDDPLKAYYPSIVDATVTIRQL
                     LTHTSGLDPYIPNRDVLNAQQLRKALNHLTQKGNKNFYYTDVNFLLLGFMLEELFSES
                     LDQIFDKTIFTPFGMYHTSFGPRPEAVPTLKGVSDGEVHDPKAKILKKHSGSAGLFST
                     LADLESFSNHYLNDPFSDCLWRNYSQQTIERSLGWNLDGDWISHTGYTGPFLMLNKKE
                     QTAAIFLTNRTYDEDDKSKWLKERQLLYNALKHDLTTPVS"
     gene            complement(13527..15854)
                     /gene="pflB"
                     /locus_tag="VCR92_000501"
     CDS             complement(13527..15854)
                     /gene="pflB"
                     /locus_tag="VCR92_000501"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEP4267592.1"
                     /translation="MATVKTNTDVFEKAWEGFKGTDWKEKASVSRFVQANYTPYDGDE
                     SFLAGATERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKENELIYGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEV
                     NLQYQALGEVVKLGDLYGVDVRRPAQNVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFGRTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDQLPETFRRYCMKMSHKHSSI
                     QYEGVTTMAKEGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHRDYKVFNVVEPITSEVLEYDEVMANFEKSLDWLTDTYVDALNIIHYMTDKYNYE
                     AVQMAFLPTHQRANMGFGICGFANTVDTLSAIKYATVKTIRDENGYIYDYEVTGDFPR
                     YGEDDDRVDDIAKWLMEAYHTRLASHKLYKNAEASVSLLTITSNVAYSKQTGNSPVHR
                     GVFLNEDGTVNTSQVEFFSPGANPSNKAKGGWLQNLNSLAKLEFSHANDGISLTTQVS
                     PRALGKTFDEQVDNLVTVLDGYFENGGQHVNLNVMDLNDVYDKIMNGEDVIVRISGYC
                     VNTKYLTPEQKTELTQRVFHEVLSMDDAAEAISSK"
     gene            16063..17157
                     /gene="dinB"
                     /locus_tag="VCR92_000502"
     CDS             16063..17157
                     /gene="dinB"
                     /locus_tag="VCR92_000502"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEP4267593.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPALKGKPVVIGKD
                     PRETGGRGVVSTCNYEARKYGIHSAMSSKEAYERCPKAIFISGNYEKYRTVGDQIRRI
                     FKRYTDVVEPMSIDEAYLDVTNNKLGIKSAVKIAKLIQHDIWKEVGLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLKEDALCFLAKLPIEKFHGVGKKSVEKLHDMGIYTGQDLLA
                     VPEMTLIDHFGRFGFDLYRKARGISNSPVKSDRIRKSIGSERTYAKLLYQETDIKAEI
                     SKNAKRVAALLQDHKKLGKTIVLKVRYADFTTLTKRVTLPELTRNAAQIEQVAGDIFD
                     SLSENPAGIRLLGITMTNLEDKVADISLDL"
     gene            complement(17250..17732)
                     /locus_tag="VCR92_000503"
     CDS             complement(17250..17732)
                     /locus_tag="VCR92_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267594.1"
                     /translation="MISYEKVRQALKTSTIAIIILNGLGVVLSLMGFAGIFYLQSQLK
                     NEAFRAQLTTEQLAQLQSSMTPFMIFLSILNVLAIIAIIVFCAQNLSKLKQGLTVSYI
                     PYILGLILSVIGLVNQFTTTMSMVGTILILIQAALYGFAFYKAKTLNEKGDDTDQAML
                     "
     gene            complement(17823..20186)
                     /locus_tag="VCR92_000504"
     CDS             complement(17823..20186)
                     /locus_tag="VCR92_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEP4267595.1"
                     /translation="MEYVFTGTVDRIIFENQANFFKILLLAIEDTDSDIDDFEIIITG
                     TMADIIEGDDYTFWGELTQHPKYGQQLKLSRYQKIKPSSSGLVNYFSSDHFKGIGKKT
                     AEKIIALYGHNTIDHILEDPSKLETISGLSKANRQAFVAKLKLNYGTEQLIAGLVELG
                     LSNRFAFQAFEKYKEEALDLVKENPYQLVEDLQGFGFKMADALAENLGIESGSPKRFR
                     AALLHCLLEESINRGDTYVQARQLLDFAITLLEDARQVECDPAAVAEQLSELIIEGKI
                     KNSDTKLFDASLYFAEEGIANNISRLLDTPLSQSFSHDTIQTTIQAVQKDFAITYDQV
                     QQEAITKALTSKVFLLTGGPGTGKTTVIRGILQAYANLHQIDLDKKDLPILLAAPTGR
                     AARRMNELTGLPSATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLG
                     AINSTTQVIIVGDSDQLPSVGPGQVLSDLLKVNSLPQIALQKIFRQSQESTIVNLADQ
                     MRRGILAADFRDKKADRSYFEAQAAFIPDMIQKIVLSAIKSGIPAEEIQILAPMYKGQ
                     AGINHLNQLMQELLNPLQGQTEFLFNDTHFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDELILDFDGSEVTYPRNEWLKLTLAYAMSIHKSQGSEFQVVILPITRQ
                     SGRLLQRNVIYTAITRSKSKLILLGEYTAFEYAIKHEGDKRQTYLIERFQEQSDLASS
                     QSTNSNPTENSQSDNDDFRLTPENYSTIDSMIGLTESDIALFFQKKS"
     gene            complement(20244..20837)
                     /gene="lepB"
                     /locus_tag="VCR92_000505"
     CDS             complement(20244..20837)
                     /gene="lepB"
                     /locus_tag="VCR92_000505"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEP4267596.1"
                     /translation="MKQFIKEWGPFTLFLILFGLSRLFLWQAVKVDGHSMDPTLAHGE
                     RLIVFNQARIDRFDIVVAQEEENGQKKEIVKRVIGLPGDTISYNDDTLYINGKKTVEP
                     YLAEYLKQFKNDKLQKTYAYNTLFQQLAETSDAFTTNSEGQTRFEMSVPKGEYLLLGD
                     DRIVSRDSREVGSFKKENLIGEVKARFWPLNKMTVFN"
     gene            complement(20848..21750)
                     /locus_tag="VCR92_000506"
     CDS             complement(20848..21750)
                     /locus_tag="VCR92_000506"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEP4267597.1"
                     /translation="MNTLVLKIDAILSKHLKKQLAPYTISSQNIYVAFAAKKNGVTVL
                     LYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAV
                     VASFVDPKDHPFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGK
                     SKPYNTISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLT
                     FQEKAESHYLAVAVSSIIARNLFLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYG
                     MSSLEYSAKLHFANTHKAQALLTK"
     gene            21907..22215
                     /locus_tag="VCR92_000507"
     CDS             21907..22215
                     /locus_tag="VCR92_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267598.1"
                     /translation="MKSINRYKFTFGEKTLTLTTDKDNLFMEEVERVAKEKYQALKNH
                     LPEADDETIAILMAINTLSTQLSREIAIEKMEAEILDLRQKTLVGLQEKANQIDVNEV
                     "
     gene            22218..22763
                     /locus_tag="VCR92_000508"
     CDS             22218..22763
                     /locus_tag="VCR92_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEP4267599.1"
                     /translation="MLSLLIVLVLTWNFYIGYSRGIILQSFYVLGALLSLLVANRFYI
                     GLAHKLTLWIPYSNPVEGTSVFFFKSVDIFVLDKVYYAGLAFFIIFLLGYALSRFLGI
                     FVHFLLLDYFDNQWTKCLSGGLALLVSLLFLNMLLSIFATVPMPFLQHYLHSSFLARL
                     VIEHLPPLTIIIQKLWIQAII"
     gene            22912..25251
                     /locus_tag="VCR92_000509"
     CDS             22912..25251
                     /locus_tag="VCR92_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEP4267600.1"
                     /translation="MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIE
                     KSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLELSADLNIQELLAIKKVLQSSSDM
                     IHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
                     SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTV
                     YIEPRAVVTLNEEITQLRADERHEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRA
                     KYLFMSDNKATIPKISDDSTLALINVRHPLLSNPVANDLHFDHDLTAIVITGPNTGGK
                     TIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHI
                     VSILNEADRNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYG
                     IETNFVENASMEFDAETLSPTYRFMQGVPGRSNAFEIASRLGLAPFIVKQAKQMTDSD
                     SDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKELEKIYQ
                     EAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKK
                     IKAARAPRIGDDIIVTSYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQ
                     KVKNKQINVVKKADSSGPRARLDLRGKRYEEAMQELDHFIDQALLNNMGQVDIIHGIG
                     TGVIREGVTKYLRRHKHVKHFAYASQNAGGSGATIVTLG"
     gene            25255..25755
                     /locus_tag="VCR92_000510"
     CDS             25255..25755
                     /locus_tag="VCR92_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEP4267601.1"
                     /translation="MESYEHFYAKLSQPFRKKPQLIILLNVLLKIITGVMYILYPSFL
                     IFTLWQGMTFQLWLRLLIIPAVGFIALSYIRKRFDFPRPYEKWNIKPLIDKDTKGRSM
                     PSRHVFSATMISMCLLRYYVYFGIVCLILSVLLAICRVIAGIHYPKDVIVGYLIGLML
                     GLCLLI"
     gene            25836..26150
                     /gene="trxA"
                     /locus_tag="VCR92_000511"
     CDS             25836..26150
                     /gene="trxA"
                     /locus_tag="VCR92_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEP4267602.1"
                     /translation="MALEVTDATFVEETKEGLVLIDFWATWCGPCRMQAPILEQLSQE
                     IDEDELKILKMDVDENPETARQFGIMSIPTLMFKKDGEVVKQVAGVHTKDQLKAIIAE
                     LS"
     gene            complement(26202..26790)
                     /locus_tag="VCR92_000512"
                     /pseudo
     CDS             complement(26202..26790)
                     /locus_tag="VCR92_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402392.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(26866..27990)
                     /gene="mutY"
                     /locus_tag="VCR92_000513"
     CDS             complement(26866..27990)
                     /gene="mutY"
                     /locus_tag="VCR92_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEP4267603.1"
                     /translation="MWDNETIASFRRTLLGWYDQEKRDLPWRRTTNPYYIWVSEIMLQ
                     QTQVNTVIPYYKRFLEWFPQIKDLADAPEEQLLKAWEGLGYYSRVRNMQKAAQQVMVD
                     FGGIFPHTYDDIASLKGIGPYTAGAIASISFNLPEPAVDGNVMRVMARLFEVNYDIGD
                     PKNRKIFQAIMEILIDPDRPGDFNQALMDLGTDIESAKTPRPDESPIRFFNAAYLNGT
                     YGKYPIKNPKKKPKPMRIQAFVIRNQNGQYLLEKNTKGRLLGGFWSFPIIETSPLSQQ
                     LDLFDDNQSNPIIWQTQNETFEREYQLKPQWTDNHFPNIKHTFSHQKWTIELIEGVVK
                     ATDLPNAPHLKWVAIEDFALYPFATPQKKMLETYLKQKNA"
     gene            28188..28481
                     /locus_tag="VCR92_000514"
     CDS             28188..28481
                     /locus_tag="VCR92_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267604.1"
                     /translation="MFQKLKNLIDRYSWFVFIMMILVLFLNYIYPFDPSLSGLQLEWL
                     IMTQVFPGLGIVCAMVAIIFKKFNLFVLALILYFALWLKLFLAFSFFTYFLGV"
     gene            28654..28944
                     /locus_tag="VCR92_000515"
     CDS             28654..28944
                     /locus_tag="VCR92_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEP4267605.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAAALNEFDRLSKINGDILRHMIVKLDA"
     gene            28966..29457
                     /locus_tag="VCR92_000516"
     CDS             28966..29457
                     /locus_tag="VCR92_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEP4267606.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRTFKSQNGER
                     EADFINCVIWRQPAENLANWAKKGALIGVTGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREGGSTGSFNGGFNNNTSSSNSYSAPAQQTPNFGRDDSPFGNSNPMDISDDD
                     LPF"
     gene            29622..29861
                     /locus_tag="VCR92_000517"
     CDS             29622..29861
                     /locus_tag="VCR92_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEP4267607.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(29994..30650)
                     /locus_tag="VCR92_000518"
     CDS             complement(29994..30650)
                     /locus_tag="VCR92_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEP4267608.1"
                     /translation="MELQELTKKNQEFIHTATNKLIQDGKSDEDIKLILEEAIPAILE
                     NQKKGVTARNLLGTPTAWAASFSQDPSQKAAETDKNTNPWLMWLDTSLLFIGIVALLN
                     GIMTFFNTNATVTGLISLLALGFGGGASMYATYYFIYRHLGKDKSLRPSWFKIIAALS
                     LAMLIWIALYSATAFLPTSLNPQLPPLALLIIGGISLALRYYLQRKYNIQNTMSPVNK
                     "
     gene            complement(30783..31727)
                     /locus_tag="VCR92_000519"
     CDS             complement(30783..31727)
                     /locus_tag="VCR92_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEP4267609.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESMKIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPIYEERNNKSYYITMPLGIIVTENAVITT
                     CLHDMTLFDHFHNRRVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QNNWLPLNGLEHAFWYITLIAMLLSSFVVIYFIRKKWF"
     gene            31930..34758
                     /gene="uvrA"
                     /locus_tag="VCR92_000520"
     CDS             31930..34758
                     /gene="uvrA"
                     /locus_tag="VCR92_000520"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEP4267610.1"
                     /translation="MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKK
                     GQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSVEAALRLGDGYLMIDTMDGNELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKSLREGALAPWNPISSNYYPTMLEQAMASFGVDMDTP
                     FEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYT
                     RNVMRGYMNELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELEL
                     TENESTIAKPIVKEIHDRLTFLNNVGLNYLTLSRAAGTLSGGESQRIRLATQIGSNLS
                     GVIYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GEFGGEIIASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNL
                     QSLDVRFPLGKFIAVTGVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHI
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     IVATGTPEEVAQVKESYTGHYLKVKLQQ"
     gene            34874..35947
                     /locus_tag="VCR92_000521"
     CDS             34874..35947
                     /locus_tag="VCR92_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEP4267611.1"
                     /translation="MSGFLEQRLGHCLRQMAEKGLEALLVTHLTNSYYLTGFSGTAAT
                     VLITAKRRVLITDSRYTLLAKASVEGFDIIESRTPLKVVAELLEADQIDCLGFEDQVS
                     FSFYQAMQAELSGITLLAQSGFVEHLRFIKDTSEIDTIAKACSISDKAFEDALDFIKP
                     GTTTERDLANFLDFRMRQYGASGTSFDIIVASGYRSAMPHGRASDKVIQNKESLTMDF
                     GCYYNHYVSDMTRTIHIGQVTDEEREIYALVLAANKALIDKASAGMTYSDFDGIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHENPFFGKSEQLLQAGMVVTDEPGIYLDNKYGVRIE
                     DDLVITETGCQVLTLAPKELIVL"
     gene            35981..36448
                     /locus_tag="VCR92_000522"
     CDS             35981..36448
                     /locus_tag="VCR92_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEP4267612.1"
                     /translation="MTNRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEDGHCIRTVHAEMNALIQCAKEGISTDGTEIYVTHFPCINC
                     TKALLQAGIKKITYKAHYRPHPFAIELMEKKGVAYVQHDVPHIILGGKEGPNG"
     gene            36536..37093
                     /gene="efp"
                     /locus_tag="VCR92_000523"
     CDS             36536..37093
                     /gene="efp"
                     /locus_tag="VCR92_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEP4267613.1"
                     /translation="MIEASKLKAGMTFESEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTDTYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGSEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEAGQKLIINTAEGTYVSRA"
     gene            37139..37528
                     /locus_tag="VCR92_000524"
     CDS             37139..37528
                     /locus_tag="VCR92_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEP4267614.1"
                     /translation="MTTEHIGEIVISPRVLEVITGIATTQVEGVHSLHNKKMADSFNK
                     ASLGKGVYLQTEEDGSVTADIYVYLQYGVKVPTVSMNIQKTVKSAVYDMAEVPISAVN
                     IHVEGIVAEKTPKPDLKSLFDEDFLDD"
     gene            37521..37973
                     /gene="nusB"
                     /locus_tag="VCR92_000525"
     CDS             37521..37973
                     /gene="nusB"
                     /locus_tag="VCR92_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEP4267615.1"
                     /translation="MTNSFQNSRRDLRERAFQALFNIEMGAELLAASQFAYGYDKVTG
                     EDAQVLELPIFLLSLVTGVNNHKEELDNLISTHLKKGWSLERLTLTDKTLLRLGLFEI
                     KYFDETPDRVALNEIIEVAKKYSDETSAKFINGLLSQYVSEAPSANKS"
     gene            complement(38114..39079)
                     /locus_tag="VCR92_000526"
     CDS             complement(38114..39079)
                     /locus_tag="VCR92_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP4267616.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINQKGYLSQKTVNKVNKAMREL
                     GYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEHNP
                     VKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEG
                     GKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQLKRSAEIIKLPNNLSPVRR
                     EMEIKSILATRKPDGLFVSDDLTAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVP
                     QLATIRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGASI"
     gene            complement(39084..40523)
                     /locus_tag="VCR92_000527"
     CDS             complement(39084..40523)
                     /locus_tag="VCR92_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEP4267617.1"
                     /translation="MDLPQAIRYRPYKEWSSKDYQAITEKMAQSPWHSQFHVEPKTGL
                     LNDPNGFSYFNGHYHLFYQNWPYGAAHGLKQWVHMTSTDLVHFTETRSRLLPDHAHDS
                     HGAYSGSAYAIDDKLFLFYTGNVRDANWVRTPLQVGAWMDKQGNISKIPQVLIEQPDD
                     VTEHFRDPQLFSYQGQFYAIIGAQGLDGKGKIKLYKAVDNHVDNWRFIADLDFDDSGT
                     EYMIECPNLVFVDDKPVLIFSPQGLAKADLDYQNIYPNTYKIFESFNPETGQLLGGGA
                     LQNLDFGFEAYATQAFSSPDGRVLAVSWIGLPDIDYPTDRYDYQGALSLVKELRIKDG
                     ILYQTPVSALQNLRGPAELFHNKIDSSNCYELELTIPGQKKLDLLLFADQKGNGLRLK
                     VDTTKGQLSIDRSRAGVQYAQDYGTVRSCQIPQGHVTLNVYVDNSILEIFINQGQKVL
                     TSRVFPTQGQTGIQVVEGQAFGHYYEMRY"
     gene            40765..42648
                     /locus_tag="VCR92_000528"
     CDS             40765..42648
                     /locus_tag="VCR92_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEP4267618.1"
                     /translation="MDNRQIATEVIEALGGRENVRSVAHCATRLRVMVHDEGKIDKEK
                     AEAIDKVKGAFFNSGQYQMIFGTGTVNNIYDEVVALGLPTSSTSEQKAEAGKQGNIFQ
                     RAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVF
                     HSLENLVLAGTQAVLHLPFGIAGLIVGGIQQLIVVTGIHHIFNFLEAQLIANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSTKLKGLAFPSTLSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGALGGWVAGLFGIAGTGFGITVLPGTLLYLNGHLLQYLVTMLVGLGVAFGIA
                     YTWGYQDRETLPLPAVEVDQTADQPALAEETLYSPLNGTVVDLAAVSDPVFSSGAMGQ
                     GLAIKPEDNTLYSPVDGKVEIVFETGHAYAITSSQGAEVLLHIGIDTVSMAGDGFESL
                     VAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIVTNSADYQSVDILAQGHVLIGDQVA
                     LIK"
     gene            42879..45893
                     /locus_tag="VCR92_000529"
     CDS             42879..45893
                     /locus_tag="VCR92_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEP4267619.1"
                     /translation="MDKHLLVKRTLGCVCAATLMGAALATHHDSLNTVKAEEKTVQVQ
                     KELSSIDSLHYLSENSKKEFKEELSKAGQESQKVKEILAKAQQADKQAQELAKMKIPE
                     KIPMKPLHGPLYGGYFRTWHDKTSDPTEKDKVNSMGELPKEVDLAFIFHDWTKDYSLF
                     WKELATKHVPKLNKQGTRVIRTIPWRFLAGGDNSGIAEDTSKYPNTPEGNKALAKAIV
                     DEYVYKYNLDGLDVDVEHDSIPKVNGEASDENLKRSIDVFEEIGKLIGPKGADKSRLF
                     IMDSTYMADKNPLIERGAPYIDLLLVQVYGARGEQGEFQNDTKLVTDTPEERWQGYSK
                     YIRPEQYMIGFSFYEERAGSGNLWYDINSRKDEDKANGINTDITGTRAERYARWQPKT
                     GGVKGGIFSYAVDRDGVAHQPKQIAEKDKQNVKNNQPQIPEITDNIFHSDYSVSKALK
                     TVMLKDKSYDLIDEKDFPDKALREAVMAQVGTRKGDLERFNGILRLDNPAIQSLEGLN
                     KFKKLAQLDLIGLSRITKLDQSVLPANMKPGKDTLETVLETYKKDNKEEPATIPPVSL
                     KVSGLTGLKELDLSGFDRETLAGLDVATLTSLEKVDISGNKLDLAPGTENRQIFDTML
                     STVSNHVGSNEQTVKFDKQKPTGHYPDTYGKTSLRLPVANGKVDLQSQLLFGTVTNQG
                     TLINSEADYKAYQNQQIAGRSFVDSNYHYNNFKVSYENYTVKVTDSTLGTTTDKTLAT
                     DKEETYKVDFFSPADKTKAVHTAKVIVGDEKTMMVNLAEGATVIGGSADPVNARKVFD
                     GQLGSETDNISLGWDSKQSIIFKLKEDGLIKYWRFFNDSARNPKTTNKPIQEASLQIF
                     NIKDYNLDNLLENPNKFDDEKYWITVDTYSAQGERATAFSNTLNNITSKYWRVVFDTK
                     GDRYSSPVVPELQILGYPLPNADTIMKTVTIAKGLSQQKDKFSQKMLDELKIKEMALE
                     TSLNSKIFDVTAINANAGVLKDCIEKRQLLKK"
     gene            46157..47041
                     /locus_tag="VCR92_000530"
     CDS             46157..47041
                     /locus_tag="VCR92_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEP4267620.1"
                     /translation="MGKLYGSIEAGGTKFVCAVGDEEFTVVDKTQFLTTTPEETIART
                     IAYFKAFEADLAGMAIGSFGPIDIDPSSETYGHITTTPKSGWANVDLLGQLSAAFKIP
                     FDVTTDVNSSAYGEVLARPGVESLVYYTIGTGIGAGAIQHGHFIGGLGHTEAGHTYVM
                     PHPDDMAKGFLGVCPFHKGCLEGMAAGPSIEARTGVRGERLDQEADVWDIQAFYIAQA
                     ALQATMLYRPQVIVFGGGVMTQEHMVLRVHDKFTTLLSGYLPVPDLTDYIVTPAVADN
                     GSATLGNFALAKLAAQGK"
     gene            47136..48089
                     /gene="manA"
                     /locus_tag="VCR92_000531"
     CDS             47136..48089
                     /gene="manA"
                     /locus_tag="VCR92_000531"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEP4267621.1"
                     /translation="MSEPLFLKSTMHDRIWGGTKLRDVFAYNIPSDTTGEYWAISAHP
                     NGVSTVTNGRYQGQPLNTLYAQEPALFGNPKEEVFPLLTKILDANDWLSVQVHPDDAY
                     GREHEGELGKTECWYIISAEEGSEIVYGHQAKSKEDLRAMIEAGAWDDLLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRKDVNGNLRDLHIEKSIDVLTI
                     GKPENSVPATIVLDNMVETTLVSTPFFTVYKWVTSQMVDMKQAAPYLLVSVLKGQGKL
                     YVDQKAYELEKGMHFILPNDVKSWSFDGQLEMIVSHPNQLV"
     gene            48223..50742
                     /gene="secA"
                     /locus_tag="VCR92_000532"
     CDS             48223..50742
                     /gene="secA"
                     /locus_tag="VCR92_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEP4267622.1"
                     /translation="MANILRKVIENDKGELRKLEKIAKKVESYADQMVSLSDRDLQGK
                     TLEFKERYQKGETLEQLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEMRT
                     GEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLTSVDYVIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGSDRIKAFLDRMKLDE
                     EDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHARSNRKDAIDAIVTFARTSLVPEESISAKELRGLKDD
                     QIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAP
                     QNIQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS"
     gene            50858..51214
                     /locus_tag="VCR92_000533"
     CDS             50858..51214
                     /locus_tag="VCR92_000533"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEP4267623.1"
                     /translation="MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYK
                     RRLSYLAGRWAGKEAFAKAIGTGIGRLTFQDIEILNDVRGCPILTKSPFKGNSFISIS
                     HSGNYVQASVILEDKK"
     gene            51211..52311
                     /locus_tag="VCR92_000534"
     CDS             51211..52311
                     /locus_tag="VCR92_000534"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEP4267624.1"
                     /translation="MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAY
                     GHGAVQVSKALLPQVDGYCVSNLDEALQLRQAGIDKEILILGVLLPNELELAVANAIT
                     VTIASLDWIALARLEKKECQGLKVHVKVDSGMGRIGLRSSKAVNLLIDSLKELGADVE
                     GIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVR
                     LGIVSYGLNPSGSDLSLPFPLQEALSLESSLVHVKMISAGDTVGYGATYTAKKSEYVG
                     TVPIGYADGWTRNMQGFSVLVDGQFCEIIGRVSMDQLTIRLPKAYPLGTKVTLIGSNQ
                     QKNISTTDIANYRNTINYEVLCLLSDRIPRIY"
     gene            52398..53909
                     /locus_tag="VCR92_000535"
     CDS             52398..53909
                     /locus_tag="VCR92_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEP4267625.1"
                     /translation="MNKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSD
                     SSSKEENNKNAAPTTSDKTDQGPLDASAETNSNSLVNADDKKRSDSSQSAVGSSNNKA
                     EAENQVDDKSTDHSKPTDQPKPTDQPKPSPSKVDTAPASSLSRQLPEARTPIQSLSPY
                     VSDLDLSEIDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYGIKADQIDSYLKSTGIAYD
                     STRINGEKLLQWEKKSGLDVRAIVAIAMSESSLGTQGIATLLGANMFGYAAFDLDPTQ
                     ASKFNDDSAIVKMTQDTIIKNKNSNFALQDLKAAKFSRGQLNFASDGGVYFTDTTGSG
                     KRRAQIMEDLDKWIDDHGGTPAIPAELKVQSSASFASVPAGYKLSKSYDVLGYQASSY
                     AWGQCTWYVYNRAKELGYQFDPFMGNGGDWKYKAGYALSKTPKVGYAISFAPGQAGAD
                     GTYGHVSIVEDVRKDGSILISESNCIGLGKISYRTFTAQQAEQLTYVIGKSKN"
     gene            54399..58226
                     /gene="shr"
                     /locus_tag="VCR92_000536"
     CDS             54399..58226
                     /gene="shr"
                     /locus_tag="VCR92_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein Shr"
                     /protein_id="HEP4267626.1"
                     /translation="MKKISKCAFVAISALVLIQATQTVKSQEPLVQSQLVTTVALTQD
                     NRLLVEEIGPYASQSAGKEYYKHIEKVIVDNDVYEKSLEGERTFDINYQGIKINANLI
                     KDGKHELTIVNKKDGDILITFIKKGDKVTFISAQKLGTTDHQDSLKKDVLSDKTVPQN
                     QGTQKVVKSGKNTANLSLITKLSQEDGAILFPEIDRYSDNKQIKALTQQITKVTVNGT
                     VYKDLISDSVKDTNGWVSNMTGLHLGTKAFKDGENTIVISSKGFEDVTITVTKKDGQI
                     HFVSAKQKQHVTAEDRQSTKLDVTTLKKAIKEADAIIAKESNKDAVKDLAEKLQVIKD
                     SYKEIKDSKLLADTHRLLKDTIESYQAGEVSINNLTEGTYTLNFKANKENSEESSMLQ
                     GAFDKRAKLVVKADGTMEISMLNTALGQFLIDFSIESKGTYPAAVRKQVGQKDINGSY
                     IRSEFTMPIDDLDKLHKGAVLVSAMGGQESDLNHYDKYTKLDMTFSKTVTKGWSGYQV
                     ETDDKEKGVGTERLEKVLVKLGKDLDGDGKLSKTELEQIRGELRLDHYELTDISLLKH
                     AKNITELHLDGNQITEIPKELFSQMKQLRFLNLRSNHLTYLDKDTFKSNAQLRELYLS
                     SNFIHSLEGGLFQSLHHLEQLDLSKNRIGRLCDNPFEGLSRLTSLGFAENSLEEIPEK
                     ALEPLTSLNFIDLSQNNLALLPKTIEKLRALSTIVASRNHITRIDNISFKNLPKLSVL
                     DLSTNEISNLPNGIFKQNNQLTKLDFFNNLLTQVEESVFPDVETLNLDVKFNQIKSVS
                     PKVRALIGQHKLTPQKHIAKLEASLDGEKIKYHQAFSLLDLYYWEQKTNSAIDKELVS
                     IEEYQQLLQEKGSDTVSLLNDMQVDWSIVIQLQKKASNGQYVTVDEKLLSNDPKDDLT
                     GEFSLKDPGTYRIRKALITKKFATQKEHIYLTSNDILVAKGPHSHQKDLVEKGLRALN
                     QKQLRDGIYYLNASMLKTDLASESMSNKAINHRVTLVVKKGVSYLEVEFRGIKVGKML
                     GYLGELSYFVDGYQRDLAGKPVGRTKKAEVVSYFTDVTGLPLADRYGKNYPKVLRMKL
                     IEQAKKDGLVPLQVFVPIMDAISKGSGLQTVFMRLDWASLTTEKAKVVKETNNPQENS
                     HLTSTDQLKGPQNRQQEKTPTSPPSAATGIANLTDLLAKKATGQSTQETSKTDDTDKA
                     EKLKQLVRDHQTSIEGKTAKDTKTKKSDKKHRSNQQSNGEESSSRYHLIAGLSSFMIV
                     ALGFIIGRKTLFK"
     gene            58423..59298
                     /locus_tag="VCR92_000537"
     CDS             58423..59298
                     /locus_tag="VCR92_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEP4267627.1"
                     /translation="MTKVVIKQLLQVIVVFMISLSTMTGVVYADKGQIYGCIIQRNYR
                     HPISGQIEDSGGEHSFDIGQGMVEGTVYSDAMLEVSDAGKIVLTFRMSLADYSGNYQF
                     WIQPGGTGSFQAVDYNITQKGTDTNGTTLDIAISLPTVNSIIRGSMFVEPMGREVVFY
                     LSASELIQKYSGNMLAQLVTETDNSQNQEVKDNQKPVDTKLGESQDESHTGAMITQNK
                     PKANSSNNKSLSDKKILPSKMGLTTSLELKKEDKFRSKKDLSIMIYYFPTFFLMLGGF
                     AVWVWKKRKKNDKTM"
     gene            59282..60166
                     /gene="isdE"
                     /locus_tag="VCR92_000538"
     CDS             59282..60166
                     /gene="isdE"
                     /locus_tag="VCR92_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEP4267628.1"
                     /translation="MIKRCKGIGLALMAFFLVACVNQHHKTAKESEQQRIVATSVAVV
                     DICDRLNLDLVGVCDSKLYTLPKRYDAVKRVGLPMNPDIELIASLKPTWILSPNSLQE
                     DLEPKYQKLDTEYGFLNLRSVEGMYQSIDDLGNLFQRQQEAKELRQQYQDYYRAFQAK
                     RKGKKKPKVLILMGLPGSYLVATNQSYVGNLLDLAGGENVYQSDEKEFLSANPEDMLA
                     KEPDLILRTAHAIPDKVKVMFDKEFAENDIWKHFTAVKEGKVYDLDNTLFGMSAKLNY
                     PEALDTLTQLFDHVGDHS"
     gene            60168..61190
                     /locus_tag="VCR92_000539"
     CDS             60168..61190
                     /locus_tag="VCR92_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEP4267629.1"
                     /translation="MTASDLQRDQSLLAKKRFRSGLYLVLLILSLLFLAVIALSLGGL
                     AVSYGAIVKGLFVAYDPQVALIYDLRFPRIVIALLAGAGIAVSGVLFQAVLKNPISDP
                     AIIGICSGASFMVLVSSLLLPQLLLYGPIVSFLGGGVSFLLIYGLAWKKGLNPIRLIL
                     TGIAINALFMGLSTALTSFFTSASPMVNALLAGHISQKTWADVGVLFPYTFIGLLLAL
                     LLSKTCNLLLLDDQVIRHLGIDATALRLGISLVAVLLASVATSIVGVVSFLGLIVPHM
                     SRLLVGSKHQILIPFSALLGAFVFLLADTLGRSLAYPLEISPAIIMSIVGGPYFIYLL
                     RRSDII"
     gene            61187..62023
                     /locus_tag="VCR92_000540"
     CDS             61187..62023
                     /locus_tag="VCR92_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4267630.1"
                     /translation="MSKNSSHIQVQNLSFAYEEKLVLDDLTFSIPKGKITTIMGANGS
                     GKSTLLQLLTKNLPLKQGQVWLEQEELATISLKAFAKKVAVVHQYHQVVEGLLVGELV
                     AMARLARRSFFKTTTKEDEERLAWALEVTALSDYVYRDLQHLSGGEQQRVWIAMALAQ
                     DTDIIFLDEPTTYLDIKYQLDILKLITKINQELGLTIVLVLHDINQALSLSDHLIGLK
                     DGRLYAQGQPRDLLDQQFIRDVFGVELPFVERNGQQFVLTSLVNETNDIRTQRRDRNK
                     NR"
     gene            62020..63783
                     /locus_tag="VCR92_000541"
     CDS             62020..63783
                     /locus_tag="VCR92_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEP4267631.1"
                     /translation="MMETEDTISRGKRKRLLKRLRERIAPKRYLLYVSAFLSWLQFVM
                     RMISFYLIAKTFSTFILGHAIALGRLAGLLLLLNVVGFVLAILGKQLQGIASQFARDS
                     LKQSFFEAFIDLDGQFDAHASDADILTLASQGIDSLDTYYGYYLSLSMRTKWNCTTIM
                     ILVFLIYPLAGLVFLGVLLLIPLSIVAMQKRSKQIMSHYWSSYMDVGNLFMDDLKGLN
                     TLYSYQAIERYEQEFSGKAEQFRKATMSLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LATGQLSFFNFLFFLLIATEFFTPIREQGYGMHLVMMNTKMADRIFSFLDSVPARKDN
                     KSKTAINFNQIDIQNISLAYEKKTVLSGVTMTLTKGQLTAIAGVSGQGKTSLAQLLLK
                     RQSATTGHILFDGLDSDNLLQETINQQVLYVSDQSTLLNRSIYDNLRLAANLSKKEIL
                     DWIDQHGLLSFINWLPDGLDTIVGENGNLLSPGQKQQVICARALLSKRSLYIFDEATS
                     SLDAENERIIDNLITRLAKTAIVIVITHKMSRLKGANQVLFLNTGQPACLGKPCDLYR
                     DQPTYRHLVDTQARLEASIYG"
     gene            63776..65446
                     /locus_tag="VCR92_000542"
     CDS             63776..65446
                     /locus_tag="VCR92_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4267632.1"
                     /translation="MAKPNRSTLSLVWRLLTLMKTLLPWIILAVGFAVMGFVITVSIP
                     TGIAYLGLLAIRQEVIPILALYLLIALAFLRGFVRYGEHYFGHFVAFHSLAAFRNLIF
                     KKLRALSPACLDSQDSGYLLKMIGEDIEALEVFFAHTIAPICTAILSAGLMFWYFCQS
                     SWQLALLALATYACLAIVIPIYFANILQVLLKSQNEGRKDYLSYFLESLRSVKDLLQF
                     QVLDEQFERLIKKSNHVNALDRNVAQAQFLQMALTFFWLGLMILAFSYMVFDGICHDS
                     LSFDKGLLTFIAFTASFSPFLELGRLSLGFKRAMNAARNIFDLLDENVIVDEGTKQID
                     RLRSVSFEDLSFAYPKRQELVFKDLSVTFQEKGIIGIKGESGSGKSTLVKLIMKWYNW
                     KTGDIFLNDRNSCLLNAAKLQDTIAYVPQTAQLFQQSIRENLTFGRQDISDESIWNLA
                     ETCGMKDRLLACKEGLDTIIKSPSDFSAGEGQRLELMRALLKDASCYIFDEPTSNLDS
                     LNEAILLDLIKTHCQGLVFLISHRPSTLACADHLFCVKNGSLKEVNKK"
     gene            65443..66036
                     /locus_tag="VCR92_000543"
     CDS             65443..66036
                     /locus_tag="VCR92_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEP4267633.1"
                     /translation="MKQLTIKDIMITGAFAALYFICVGLGTFINIFFDRSGNMLYAPA
                     FAALLGGTIYFLLIAKLQTFGPITLLGLMMGGFFFLSGHFFAAMFPSIIFGLIADIIA
                     SLGKYKSRFFNDLSYMVFAFVNSGPIVLMWLLKDAYVESLLARGKSMTYVNRIMYDFS
                     LGHVIWFVGIVLAGALLGSAFAHYLLKKHFIKSGLLS"
     gene            66033..66713
                     /locus_tag="VCR92_000544"
     CDS             66033..66713
                     /locus_tag="VCR92_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEP4267634.1"
                     /translation="MRLDVRTKLLLLVLANACFFFRVDGFLEFIIVIFLLLLLSALNK
                     KKLAFKLAVVYLLMIGLSVIPLSIFPSYLDHLLSFVSIAGRLVFPSLLAGLITIKTTT
                     IYELVHGLRKWHFPEVWLLTLAVMCRFIPMIRQECCVIHRSLTIRGIILTKWSILIRP
                     KQYLEYLMVPLLLSLIRSSQELTIASLTKGLAVNKGTSECFSSHLTWKDWGVQIWITV
                     IIIITILQ"
     gene            66650..68104
                     /locus_tag="VCR92_000545"
     CDS             66650..68104
                     /locus_tag="VCR92_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4267635.1"
                     /translation="MERLGGADLDYCYHNHHDTAMISAEQLVFTYHDQKNPACQVSTC
                     QIASGQFIVLCGPSGSGKSTFLKLLNGIIPDYYAGKYEGRLDVADCQADRDSVETFSR
                     SVASVFQNPASQFFYREVQHELVFPCENQGLDAKVIMKRLWTLAEDFAFAELLNKDMF
                     GLSGGQKQRVAIATAIMQGTNIMLFDEPTANLDSAGIAAVKAYLTQLKAAGKTIIVAE
                     HRLHYLMDLADNFFYFKNGRLTDKLTTQDLLALTDEQRQDMGLRRLDLSDLKPVLAGK
                     IESQHYRPDDSLCIEHLTVRAGSKILRCIEQLSFAAGSISGITGSNGLGKSQLVYYIA
                     GILDDKKATIKFQGIPLSAKQRLSKTSIVLQEVSLQLFAESVSKEVNLGHERHPRTTE
                     VIERLSLTTLLERHPASLSGGEQQRVMIAASLLADKDILIFDEPSSGLDLLQMKALAN
                     LLMQLKTQHKVVILISHDEELLSSVCDTIYQMLP"
     gene            68479..70494
                     /gene="recG"
                     /locus_tag="VCR92_000546"
     CDS             68479..70494
                     /gene="recG"
                     /locus_tag="VCR92_000546"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEP4267636.1"
                     /translation="MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFK
                     SKSVFDLVDGEKAVITGLVVTPANVQYYGFKRNRLSFKLRQGEAVLNVSFFNQPYLAD
                     KIELGQEVAVFGKWDATKSAITGMKVLAQVEDDMQPVYRVAQGISQSTLIKAIKSAFE
                     IDAHLELKENLPATLLEKYRLMGRSQACLAMHFPKDITEYKQALRRIKFEELFYFQMN
                     LQVLKAENRSETNGLPILYSKHAMETKISSLPFILTNAQKRSLDDILSDMSSGAHMNR
                     LLQGDVGSGKTVIAGLSMYAAYTAGFQSALMVPTEILAEQHYISLQELFPDLSIAILT
                     SGMKAAVKRTVLAAIANGSVDMIVGTHALIQDSVQYHKLGLVITDEQHRFGVKQRRIF
                     REKGENPDVLMMTATPIPRTLAITAFGEMDVSIIDELPAGRKPIMTRWVKHEQLGTVL
                     EWVKGELQKDAQVYVISPLIEESEALDLKNAVALHAELSTYFEGIAKVALVHGRMKND
                     EKDAIMQDFKDKKSHILVSTTVIEVGVNVPNATIMIIMDADRFGLSQLHQLRGRVGRG
                     YKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLAESDLKMRGSGEIFGTRQSGIPEFQ
                     VADIVEDYPILEEARKVSAAIVSDPNWIYEKQWQLVAQNIRKKEVYD"
BASE COUNT        21783 a        12336 c        14758 g        21806 t
ORIGIN      
        1 atcaataaag acaaaaaaaa tatctgctgt acttgaaaaa gtagggctct ctagtggcta
       61 tttaaatcaa aaaatatatg aattgtctgg agggcaggct cagcgtgtag ctattgcaag
      121 aatgttaatg aagccacgta aaataatttt agcagatgag ccaacaggag ctttggatgg
      181 tgaaattgga aaagaaatta ttaatttgtt gttgagcgaa acagccgaaa ataaatacgt
      241 tattatagca actcatgatc cagctgtata taataaggtt gattttataa ttgatatgaa
      301 agatataggg agtaagaaat gaaaaagaaa atttatattg gcttgattgt cattgttgga
      361 gtttttgtag tgttcttgtc tggaaaacaa atcacacaaa aagaaacttc aaataagcct
      421 gtggtgaccc taacagttta taccatctcc tctagtgata cccaaaaatg gagtaaagta
      481 aagcagtttg aaacgaaaga agcaatatac ctagtaaagg taaaagaaac tacctcttca
      541 gaagaagtct tttcaaacat cattgcagat ggaatggcag ttggttttgg agttagtgaa
      601 gaagacgtta aacagtttaa cgataattta tgtagcccgg tagaagatgc taagaataat
      661 aaattaattg gaatagaatt catcaatttt tctagtgttg ataaggggtt tgtggttgca
      721 aattttgact acggcaaaaa agcgtttaat tctcagaaaa cagaaaataa aaaattatat
      781 aaaaagctct atgaagcgta taaaggatag ctatttatag ttttttgaga gtgataccac
      841 ttctgaataa taaatgaact aacatggcat accgttttct attcatctaa caatgttttc
      901 aagaaataat tgatgccttt agcacgactg aaatgaggtc aaattgacag aatactccta
      961 ttatggtact atttttaata agaatattca gtgatagtga taaagaggaa aatatgggaa
     1021 ttgaaaagac agttagtgaa ctagctgata ttttgggagt gagtcgtcag gccgtcaata
     1081 atcgtgttaa gtctttaccc gaagaagatc ttgacaaaaa tgaaaaaggc gttactgtgg
     1141 ttaagcgcag tggtcttgtt aagctggaag agatctataa aaaaacaatt tttgacgatg
     1201 agcctatcag tgaagaaacg aaacaacgtg agcttttaga gattcttgtg gatgagaaga
     1261 acactgaaat cacgcgcctt tatgagcaac tcaaagccaa agatgctcaa cttgcctcaa
     1321 aagatgagca aatgcgtgtt aaagacgtgc agatcgctga aaaagataaa caattggatc
     1381 agcagcaaca attaactgct aaagccatgg ctgataaaga aaccctaaaa ctagaattgg
     1441 aagaagctaa agcagaagcc aaccaagctc gcttacaagt cgaagaagtt caggctgaag
     1501 ttggccctaa aaaaggcttt ttaacccgct tgtttgcgaa ataatcacaa aaaatgacga
     1561 aggccctatc agggtctttt ttggaggaaa acatgaaaca cttagatact tatattgcct
     1621 ttgatttaga atttaacact gtcaatgacg ttagtcatgt cattcaagta tcagcagtca
     1681 aatatgacca ccataaagaa gttgacagct ttgacaccta tgtttacaca gatgttccct
     1741 tacagagttt tatcaatggc ctaacaggaa tcacatctga caagattgct gcggcaccaa
     1801 aagtagagga ggttatggct gcgtttaaaa attttgtggg agagttacca ctgattggtt
     1861 ataatgctca aaaatctgac ctgcctattc tagctgaaaa tggcttagat ttaagggacc
     1921 aataccagat tgacctcttt gatgaagctt acgatagacg tagcgcagac ttaaatggga
     1981 ttgctaacct tcgtctgcaa acagtggcaa cctttttagg cattaagggt cgaggtcata
     2041 atagcttaga agatgccaga atgacagcag caatctataa gtcattttta gaaacagata
     2101 caaacaaagc atatctcagc cagcaagaag aggtaaccac agataaccct ttcgcagctt
     2161 tgggagactt ttttgactaa gggctctgct atttctaaaa aataacaaaa attcctaggg
     2221 ttagctcttg cttgtaacgc taggtcatgt gataagatag gggcatatca agagggagtc
     2281 gagtgcacac gaatcgtttt tgatcactaa atgatagaaa gaaggtgtgg aaatgtctca
     2341 attctattcg actggagaat tggccaactt agctggcgtt tctattcgaa ctgtccaata
     2401 ctatgaccaa cgtgggattt tgattccgac agctttgaca gaaggtggac ggcgactcta
     2461 tacggattct gatttagaac aattacgcat gatttgcttt ctgcgcgatt tgggattttc
     2521 cattgagcag attcgcaaag tcttagcaga ggaaaatgca gcccaggtgc tggaattgct
     2581 tctagttgat catattgcga ctgccaagga agacttggcc gcaaaagagc aacaagttga
     2641 tatagctgtc aagatacttg acagacttcg aaaacaagac ccccagtcac tagattttct
     2701 gatggacatt tcgcttagca tgaaaaatca aaaagcttgg aaaaaacgct ttattacttt
     2761 aattgtctgt ttgacagtgg aaactctact ttttgtgggt ggagcctatt ttctccaatt
     2821 gacagtctgg aaatatttat taatcccggt gttcctttta gtcttactag gaaccttata
     2881 ctggtattac caaaatatct gttatctttg tccttcttgt catcaaacat ttgaagcaaa
     2941 atggacagaa tttgcccttg caggccatac accacgaacc agaaagttaa cctgctccca
     3001 ttgccatcaa aaatcgtatt gcttggaact ggcaaaagag gacactgtct caagaggata
     3061 agcactaact cataaaaaaa ctagcctgag atccttctca agctagtttt tgttttttta
     3121 gaatggtaat ttaccagcaa aagcgcctaa tgttttctta gtcgcttcat caatttgcgt
     3181 aagggcatca ttaatggctt gagtggtcat gtcttgaagc gtttctacat cttcaggatc
     3241 tacaacagct tctttgaagt caatcccaac caatttttta tcacccgtga aagtggcagt
     3301 gacaaggtct tgagctgatt ttccagtaaa ttgcatagca gccaaatccg cctgcttttg
     3361 ctccatttgt ttctgaagct tttgtgcttg cttcatcatg ttttgcatgt tcatcataag
     3421 actatactct ccttaattta atactaacta ttataacata taaaaagagg caataaaaac
     3481 aatgtcagtt agtagactag cctgtatcag taagaaagtc gctatggata agatggatta
     3541 gcagcaaggg tctggctaat gacagaataa gtctagaaat ggattatttt tgtcatagac
     3601 tagtccgact tagtggttat ctaattcacg atcttcttta gcttgttgtt ctaaaagaat
     3661 ttgtgcgaag tcaacccact tagtgtagtt attttcggat aattgttctg aaatcatcgc
     3721 taactctcgt tgtggcaact gataagagac tcccttactt tctaaggtta aatcttcttc
     3781 cattagggcg gttaaactaa catcaaagat agcagcaata tcacttaata gaccagactt
     3841 tggagtatat tttccttttt cccactcact gattgaagaa gagctttttc gtcctaggag
     3901 attagcaagt tctaattgtt ccatgttctt ttttaatcta aggtacttta aattacttgc
     3961 aaaaaaagtt ttcttggcgg acatattttt ctccttttct ttatataaaa tatgatacca
     4021 taaaagaggt taaagcaaaa ggtatcgtaa aagatggtct aaaaactctc taaaaacttg
     4081 acttcataaa aaccgaagtt tataataaac ttaacatgat taactaatct cattttagtg
     4141 tggagggaaa attgtgacca aatcaacttt aaaagagtta agaacaacaa agaaaatgac
     4201 acagcaggaa ttgtctcact taacaggcat ttctgtcaga acgattgcta ggtatgaaaa
     4261 agatactaaa aagctaaggc gagcaaaata tgagaagcta aaaggtattg cacaagcatt
     4321 agcggtttcc gttgatgata tttttttagg aatagattcg gaatttatga actaagacga
     4381 tcgttttctg tttgctatta gtaagaccaa ttaacaaaaa agtgcttagt tatattgcta
     4441 agcactttta tttgttaatt tgatgctatt ggcacaatca attgagactg actgagatcg
     4501 atagttaaag catagttgct gttgtcacgg acagtatgtt caaaatcggt tgtgtataag
     4561 atgactcgaa gggtatctcc tttttctaga tgatagatag ttggttgcaa aggaagtcta
     4621 acagtcatcc atttattatt aggaatagtt tcaattgacg acaaattatt gcgattttgt
     4681 aaattcatga aacctttcga aataacacgg taagaatctt ctctaaatgg tagctcttta
     4741 aggggttctc tagagaaatt ttgcccattg tcaatacttg attgggtgag agcaatagga
     4801 agatcgccca agcgtttttt cttaccatag tcaaggattt gtgcagatag aagtccttta
     4861 ttttcacttg atttcacttt taactgtagg acaatttcac cgttaatagg taagtcctct
     4921 tccagtaaaa tatcaatcag ggcttgattg gccttgcctt taaagagagc tgctttggac
     4981 gcacggaaat ctttaccgta agctttaaat tcatcttcac catagtgatt atcaattaaa
     5041 agcagttcct gaccgaggtc aagctctttg atggttgagg ttccaaagac tttacgctcc
     5101 tgccagtttt gtgggcaggt gttatcctgc cagatcattt caggaaggct aaaatcatta
     5161 gctaggccta agagtttttg acataaaagg gcattcatgc tttcgcgaaa atcaatggat
     5221 tgccaattat gcatgtaaac atgctcacct tgatgtaaaa agaggtgctt gttgattgtg
     5281 gaaggaagcg cattgaaaat ctcatagacc tgtcttggtt tgacattcca gtcttgtaag
     5341 ccatgactat aaacgacatc acactttatt tgatgagcat tttttaagta attgcggtcg
     5401 tgccaaaatt gattataatc accagattgt cggtctaacg cctgagactg ttggtttagc
     5461 aattcttgat aatgatcatt atggcgaaga taatcgccag ccaataaatt acgcgagtag
     5521 gtgagctcag ttaggacatc tagatcctct ccaggatagc caccagggct acaaactaag
     5581 ccattttcgc ggtagtagtt gtaccaagaa gaaatagctg attctgcaat aatcatggct
     5641 aatccgtcta cgcctgtagt ggctaaacca gtagacatag ttcccaagta ggactttcca
     5701 gtcgtacaaa ctagaccatt tgcccaatca gctctcactt ggtgggtttt tgagtggctg
     5761 gtgtaggctg tggctcttcc atttagccaa tcaataacgg ctttaaagct ttcaatttga
     5821 gcatagtctc cactcgtcat aaagccagtg gaaccagcag ttcccacacc tgaaacatag
     5881 atattagcaa acccacgtgc gaggaaataa tcgttgaggc tataggagtt gatgtagcta
     5941 aagctttcta gattttgacc tataggaagt ttgcaaggct gtgtctcaag aggaataaaa
     6001 tccctgtctt cgacagtgat ttgtctcctt tttttaacga ctaactcttt ttccatacga
     6061 taaagttttt tgtcgttggc tacttcattg ataccttgat ggtatggact aggtgtcatc
     6121 aaagttggta atggtttttg agattgagga cgaatgatat taaccttaat aagatcaagt
     6181 tggccatctt gatcggtatc aagaggtgct tcaacgtaaa caacttctcg aatcagctgt
     6241 gacgtgtcaa aggtagctaa tgatttaccg ttgaagaaat ggtaatcatt gtccatagta
     6301 agcattcctt ggctgaccaa atcatcaatc agggtcatgc cagacttaca acgggtcgct
     6361 aataagtggt ggatatgctt gataatttct gtttcgtcaa agtggatagg aaaggccagt
     6421 ttatcaagga aagcatcggc ctctgtaaaa tcaactccag gaataaagcc aaggacttgc
     6481 agggccagta aatcaaaaac ctctttggat aactcttgct ctgattgaaa aaagctcaat
     6541 gcgtccatgt catttttggc gattagatga cttaaaggat aatcactatc agggtagtgg
     6601 aagaagattt tacgtaaaaa gctttctagg ttagctttgg cagttttttg cagatccaga
     6661 tcaaagccca attcttttaa ttcttcagcc gctctttcta gactagttgg aatataggaa
     6721 aattgattat agcgcatagg agtttccttt ctagtggctt agaaaacgat attatctttt
     6781 aatttatcaa gattggtaat gataatatgt tgtttatcaa tgcgaatgat gtttttttct
     6841 ttcaactgtt ttagaatacg gctgacgctg ctagcggtag aaatgccaca gaatttaccg
     6901 agttcctcat tagtaatgac aaaattaatt aaaatttgac catttggtag ttcttcgcca
     6961 aatagggtca ttaagtcata tatttgagta gaaatggcac cgatacggcc gttagttaac
     7021 atacattgca tttttttcat ggatttttga agacgattat ggtaaaagtc cttcacatat
     7081 ccttgtagtt caatatcttc gtttatatct tttaaaaatg ctgagcggcg aaccttgtaa
     7141 aaactagctt tctctgactc gatgcgaaca ttataaggct ctcccatatc ttttgaataa
     7201 ccagtgttga gaacagaagt aatttcaagt cctgtaacat atctcaaatt aaattccatt
     7261 ccatattttg aaagaacact ctgtttcaca atgccgtctt ttaaaatata agtgaagtcc
     7321 tcttcgagac tttcaaaagt caagtacttg tgataacttt tttcaatgat aggaaagtta
     7381 tgattatcaa tataccgttg caaaatgtga tgattcacgc ttttctccaa atattctttt
     7441 accaatgtat aatttgtatc ttcaagagaa attaacattt gctaatgccc tttgatagta
     7501 acacttatat tataccattg aaatatatta tattctgctt tttttgtaaa atgtttatga
     7561 aaatagagag gagttcattt tcaatggaag aaaaattgtt taacaaacat tttgtggcca
     7621 tcacagtaat aaactttata gtctatatgg tctactatct ttttacggtt attattgcct
     7681 ttgtggcgac tagagagcta ggagctcaga ctagccaggc aggattggca acagggattt
     7741 atattctagg gactttatta gcccgtttga tttttggaaa gcagttggag gtgtttggtc
     7801 gtcgtttggt tttaagagga ggtgctattt tttacctctt aacgacctta gcctactttt
     7861 atatgccaac gattagcatg atgtacttgg ttcgtttctt gaacggattt ggttatggtg
     7921 tagtatcaac tgcgacaaat accattgtaa cagcctatat tccagctcgt aaaagaggag
     7981 aaggaattaa tttttatggc ttgtcaacca gtctagcagc agctattggc ccttttgtag
     8041 gaacctttat gttggataat cttcatattg attttcgcat ggttattgtc ttatgtagcg
     8101 tcttgattgg gtgtgtggtt gttggtgctt ttgcttttcc agtcaaaaac atgtctttaa
     8161 atgcggagca attggctaaa accaaatcgt ggactgtgga tagtttcatt gagaaaaaag
     8221 ccttgtttat cactgcaatc gcctttttaa tggggattgc ctatgcttca gttttaggat
     8281 ttcaaaaatt atacacgtct gaaattcatt tgacaacagt aggcgcttat ttctttgtgg
     8341 tctatgcctt aatcattacc atcactcgtc cagcaatggg acgtttaatg gatgctaaag
     8401 gcgataaatg ggtcttgtac ccaagttatc tttttttagc aatgggactc ttcttgctag
     8461 gtagtgtatc gtctggagga agctatttgc tttcaggagc cttgattggc tttggttatg
     8521 gcacttttat gtcttgtggt caagccgcct ccatacaagg agtggatgag caccgcttta
     8581 atacggctat gtctacttat atgattggtc ttgatttagg tttaggtgct gggccttacc
     8641 tcttgggctt gattaaagat ttggcacttg gtagtggtgt ggcttccttt aggcacttat
     8701 tctggttagc tgctgtgatt ccactgattt gtaccttgct ttacttatta aaaacaaaga
     8761 caagacaggt tttgtcttaa ggacaagaaa aggagtttag tcttatactt aaatacaaac
     8821 gtatcttaac agctgtagat agttcctatg agccgggatt agctgtgggt aaagccatta
     8881 ctatagcgct ttgaaataat tctagtttgc tattcgtaca tgtcaataaa aatgactcgc
     8941 aaaagccatt cgtgaaagag aaaatgtggc cttattttta gtaggtacaa ttggattaag
     9001 cacgtttaga tacatgacaa ttggattaac atcagaatat aggctttgtc atgttaagat
     9061 tgatctgttg atcgtgagag ctaataaaaa atgttataat actatgaaat aaagtgataa
     9121 agataaggcc ttttatggtc cttttcttta ccgcttttat tattgtgtga aaataacact
     9181 taatgatcat tttatttatt attttattac ctttacattc atcaataagc ctgttaaaat
     9241 ggtatttgtt atattttatt atttggagga aaccagaaaa catggaaatg acatggactg
     9301 tgaaatacat cacagaattt atcgcaacgg cttttttgat tattttgggg aatggagctg
     9361 ttgctaacgt cgacttaaaa ggaacaaaag gacataactc aggttggtta gtgattgctt
     9421 ttggctatgg cttaggagtt atgatgccag ctttgatgtt tggtaatgta tctggaaacc
     9481 atattaatcc tgctttcaca gttggactag cagtatcagg cttgttccca tgggctcacg
     9541 tcttacaata cgttgtggca caattacttg gagctatctt tggtcagttg gtagtggtaa
     9601 tggtttataa accttacttt atgaaaactg aaaatccaaa tcatgtttta ggctcattct
     9661 caacgatttc atctcttgat aatggtcaaa aagacagcca taaagtctct tatatcaatg
     9721 gtttcttaaa cgaatttgta ggttcatttg ttcttttctt tggtgctttg gctttgacta
     9781 aaaactactt tggggtagag ttagttggta aattgattga agcaggttac gaccaaacaa
     9841 ctgcagcaac acaaatttca ccatacgtga caggctcatt ggcggttgct cacattggta
     9901 ttggtttctt agttatggtc ttggttactt cattaggtgg accaactggg ccagcactaa
     9961 acccagcgcg tgattttggg cctcgtttgt tacaccactt cttaccaaaa tcagttcttg
    10021 gtcaagccaa aggtgattca aaatggtggt atgcatgggt tcctgtagtt gcacctatct
    10081 tagcggcgat agtagccgta gcagcgttta aataccttta tatcagataa aaaaagaact
    10141 aaagcttctt ttagactcaa gacaagctcg cttaaggaac ttgtcttttt tatatgagtt
    10201 aagcgaaatc taatgcaaac ttgactgtct tgtatagcgt attttgtaaa ttttactaga
    10261 cttcttgtaa aaaagcctct cctcagataa gatgactaat gcctctaaac ggtgttacaa
    10321 ataaacgagg catccctaac ttcctttatc tggtgttgaa actattttgc acggactaaa
    10381 tcactgatag agtaaaaaac gatttttcat ttttgttgta aaatattaaa aacgtctctg
    10441 gttagtgatt cccagaaacg ttatcttatc tatttgtttg ttgcttatga gaggtaaagg
    10501 aggaacgaat cagcattcca ccagtgaaga aaacgatagc gatgaccaga agtttcaagc
    10561 tattaatatc taaatttgtt aagaaaaaca cagctagtaa aacgccaata ataccaccag
    10621 aaacaattcc agcaaaacca tcccaactga cacggtttgc tttgataaac tggctactag
    10681 aagctgtcat aatcatagct gcatctagca tcataacagg catagcaact gttgggctaa
    10741 gacccattaa tgaaaagaaa atcaattctg gagcataatt gcctaacccc atagtcatca
    10801 agactccaac gataaaatta aaaccaattc caacaaaaag ccagatgcca tggaggccat
    10861 gaatggtgtc tgaaaggtgt tctcctggat ggtagattat tctaatgatc atgattatag
    10921 ctgctatgat taaaagacta ccaaggattc gttggacagt tggagcatgc cagttttttg
    10981 taatatgagt ccccaaataa gctccaataa aggctgctgc agccatagca agtaaagtta
    11041 gaacctcaac ttttacgaca aaaataaagc aaagagattg aatgagcacc ggaagcacat
    11101 gagctacggt catagtgcca ggcaattgtc tatcgtcagt gactaattta gttaacttaa
    11161 agcacgttgt ggtagtagca aaagacccta tcccaagggt gtcaagggca tctgttagca
    11221 ggccaatcca aaaccccgtc caaaagcgtt taaaaggatt gatcttattt tttttaagat
    11281 gttttactaa cataaagaaa ataaaaagca ttgccgaaac tagcaaagct tgtatcagtc
    11341 taaggataag catttcgttc ataaagacta gtttacaaaa aaaaacctta gccgtcaacg
    11401 tgatttactt cattaaaaca tgccactatg cttagaagag ctttggttcg atgtattttg
    11461 ttaaaattaa gctaaaatat taatattgca tgaaagggga cgccttcctt tttcccttac
    11521 tgagcttagc tgttattgta gtgaatgttt aaaaggctag tttgtcgctc tttatcaaaa
    11581 atctagtagg atgaatacgt ataatttctt gtcaaataga ggaattttgt ctataatagc
    11641 agaggattag gaggaaatta tgactttaat ggaaaatatt acctttaaaa ctccagtatt
    11701 acgcgttaat gatcgcgacc ttaatattgc attttatcaa aataatttag ggcttcgttt
    11761 agtatctgaa gaaaatgcga ttgctatctt ttcatcttgg ggagaagggc aggaatgttt
    11821 tgtaattgaa gagtcacctt cagttagaac gcgtgcggta gaaggcccta aaaaggttaa
    11881 tacgattgtc atcaaaacaa atcaacctaa agaaatcgaa caattattag ctcatggagc
    11941 acattatgac gctcttttta aaggtcaaaa tggctatgcc tttgagacta tttccccaga
    12001 aggagaccga ttcttgttgc atgctgaaca agatattaaa catctccaag gtactgattt
    12061 accatcgctt gaaaaagatg caacttttaa aggtttaact caatttaagt ttgatattat
    12121 tgttttaaat gttattagtg aagaacgctc aaaagctttt tatcgggatc tgtttagtga
    12181 tcagttacct attactatgg attttattca agaagaaggt cccgatttgg caattgatcc
    12241 ccatattgct tgggatttag aaattttaga atttcaagtc tcaaaggact atgatatgaa
    12301 ggtcctaaaa gcaactttag aagaagacgg gcacaaggtc tacattgata aaaaacacaa
    12361 agtattggtc ctttctgatc caagtcagat cgaagtatgg tttacgaaat gactttggca
    12421 gtcattaaat gtattgaaaa ccatcttcac aaaaaagtat acaaaggggc cagtctggct
    12481 ctctttcaat ctggtcgatg gcaagaatac catatcggaa caattgatgg aagacgacca
    12541 gttgatgcta acttagttta tgacttggct agtgtttcaa aagttgttgg tgtggccaca
    12601 atatgcaata ttttattgaa taatggtacg ttagcattag atgatccctt aaaagcatat
    12661 tatcctagta ttgttgatgc gactgtcact attcgacagt tattgactca taccagtggt
    12721 cttgatcctt atattcctaa cagagatgtt ttaaatgcac aacaattaag aaaagcactt
    12781 aatcatctta ctcaaaaagg aaataaaaac ttttattaca cagatgtcaa tttcctcttg
    12841 ttaggcttta tgttagaaga gctctttagt gaatctttag accagatatt tgacaagact
    12901 atctttactc cctttgggat gtatcatacg tcttttggcc ctcgtccaga agctgtacca
    12961 acattaaagg gtgtgagtga tggggaagtt catgatccca aagcaaaaat cttaaaaaaa
    13021 cattctggat ctgcggggct attttcaact cttgcagatt tagaaagttt tagcaatcat
    13081 tatcttaatg atccattttc agattgtctg tggcgcaact acagccaaca aacaattgag
    13141 cggtcactag ggtggaattt agatggcgat tggattagtc atacaggtta cacagggccg
    13201 tttctaatgc ttaataaaaa agagcaaacg gcagctattt ttttgaccaa ccgtacttac
    13261 gacgaggatg ataaaagtaa atggttaaaa gaacgtcagt tgctttacaa tgcactaaag
    13321 catgatctga caacacccgt atcgtaacgt ctaaaggggc agttttagcg atcttattac
    13381 tgtttttaaa gtttcttcta aaaaatagcc atttcatttg tctgatgaga ttagagtgat
    13441 tataagtgaa aaaagaacag ccatctcatt ttgaatcaaa tgagatggct gttctttttt
    13501 ataagttatt gatcatttag atactactat ttacttgaaa tagcttcagc ggcatcatcc
    13561 attgaaagca cttcgtggaa gacacgttga gtcaattcag ttttttgttc tggtgtaagg
    13621 tatttggtgt tgacacagta accagagata cgcacgataa cgtcttcgcc gttcatgatt
    13681 ttgtcataaa catcgttaag gtccataacg ttcaagttaa cgtgctgacc accattttca
    13741 aagtaaccgt caagcactgt taccaagttg tcaacttgtt cgtcaaatgt tttaccaaga
    13801 gcacgaggtg atacttgagt agtcaatgag ataccatcgt tagcatgtga gaattccagt
    13861 ttagcaagtg agttaaggtt ttgtaaccag ccaccttttg ctttgttaga tgggttagca
    13921 cctggtgaga agaattccac ttggctagtg ttaactgtac catcttcgtt taagaagacg
    13981 ccgcggtgaa ctggagagtt accagtttgt ttagagtaag caacgtttga agtgatggta
    14041 agaagtgata ctgaagcctc agcattcttg taaagtttgt ggcttgcaag acgtgtgtgg
    14101 taagcttcca tcaaccattt cgcgatgtca tcaacacggt cgtcatcttc accgtaacga
    14161 gggaagtcac ctgttacttc gtagtcatag atgtagccat tttcatcgcg gatagtttta
    14221 acagttgcgt atttaatagc tgacaaggta tcaactgtgt tagcgaaacc acagataccg
    14281 aatcccatgt tagcacgttg gtgtgttggc aagaaggcca tttgaactgc ttcgtagttg
    14341 tatttatcag tcatgtagtg gatgatgtta agcgcatcta cataagtatc tgtcaaccag
    14401 tcaagagatt tctcaaagtt agccataact tcgtcgtact caaggacttc tgatgtgatt
    14461 ggttcaacaa cgttaaacac tttgtagtct ctgtgaacat catcgtaacc accgttaaga
    14521 ccagtaagaa gggctttgag aacgtttaca cgagcaccga agtattggat gttatgacgt
    14581 tgttcttcat tttctgggtc aagtggtgat acacaacatg aaatacatga catttcacca
    14641 taaccttctt tagccattgt tgtcacacct tcatattgga tagaagagtg tttgtggctc
    14701 attttcatac agtagcgacg gaatgtttct ggcagttggt cagtccaaag aactgttaag
    14761 tttggttctg gagagttacc gatattatca agagtgttta agaaacggta gtccatctta
    14821 gtcacacggt gacgaccgtc gttacccata ccagccatag aagttgtgat gaatgttggg
    14881 tcacctgagt aaagggcatc gtaagcttta gtacgaccaa attttacggt acggagttta
    14941 aggacaaaat catccacaaa ttcttggatt tctgattctg taaaggtacc gcgagcaagg
    15001 tcacgttctg caaagatatc aagaacgatt ggcacacgtc caagagaagt agcagcaccg
    15061 ttgatcacac gacatacagc catgaaagcg atgtttaccc attggatagc ttctttaacg
    15121 ttttgtgctg ggcgacgaac atcaactccg taaaggtcac caagtttaac cacttcacca
    15181 agagcttggt attgaaggtt aacttcttcg cgaagacgaa tggattcttc atcgatttca
    15241 gtgatagcat tccagtcatt gactttttct tgcatcaagt agtcagcacc gtaaagagca
    15301 agacgagcgt aaacaccgat gatacgtcca cgtgagtaag catctggaag accagttaca
    15361 gtgtgggcat gacgagcacg acgaatattt gaagtataag cgcggaagat accgtcgtta
    15421 acagttgtca cgtacttagt aaagatttcg tgtactgctg ggtctggttc atagccgttt
    15481 tctttaaggg tcgtttccgc catacggata ccaccttttg gcatgaagtt caatttgaac
    15541 aattcatcgt tttgaatacc ataaattaat tcattttctt tatcgatgaa accagcagga
    15601 atgtcagcaa ttgaagttgg acgagtatcg tatgggaaac gtgtagcttc atagtgtgct
    15661 tttgtttctt cgataacttt tttgatgtga agtgaacgtt cagtagcacc agccaagaaa
    15721 gattcatcgc catcgtatgg ggtgtagtta gcttgtacaa aacgtgagac acttgctttt
    15781 tctttccagt cagttccttt aaagccttcc caagcttttt cgaaaacatc tgtattggtt
    15841 ttaacagttg ccataaattt ctccttaaat tctagtaaca aagcgatctg ttacatttac
    15901 aattctaagt ttaacatata ggaaacgttt tcccaagcaa aattcttgac aaaattaaga
    15961 ttcttttata atacagattg ttgaaacagt cacaaactgt attagaatgt atttttttgg
    16021 ctttagatag cctaaaaggt ataatagaga aaggagggac ttatgcttat ttttccactg
    16081 attaatgaca cgtcacgaaa aatcatccat attgacatgg atgccttttt tgctgcagtt
    16141 gaggaaaggg ataaccctgc tttaaaagga aagcctgttg tgattgggaa agatccaaga
    16201 gaaacaggtg gtcgcggagt tgtttccact tgtaattacg aagcgagaaa atatggcatt
    16261 cattcggcca tgagctctaa ggaagcttat gagcgttgtc ccaaagccat ttttatttca
    16321 ggaaattatg aaaagtatcg aacagttggg gaccagatcc gccgtatttt taagcgttat
    16381 actgatgtgg tagagcccat gtccattgat gaggcctatc tagatgtcac caacaataag
    16441 ttgggtataa aatcagccgt caaaatagcc aagctgattc agcatgatat ctggaaagaa
    16501 gtaggattga cctgttcagc aggtgtgtct tataacaaat ttttggctaa attggctagt
    16561 gattttgaaa aaccccatgg cctcacccta gtcttgaaag aagatgccct gtgcttttta
    16621 gccaaactcc ccattgaaaa gtttcatggt gttggtaaaa aatcagttga aaaactgcat
    16681 gacatgggga tttatacagg acaggatttg ttggcagttc ctgaaatgac cttgattgat
    16741 cattttggtc ggtttggttt tgacctttac cgtaaagcga gaggcatcag caattctcct
    16801 gtcaagtctg atcggatacg caagtcaatt ggcagtgaga gaacctacgc taaactgctt
    16861 tatcaagaaa cagacatcaa ggcagagatc agtaaaaatg ctaagcgcgt ggccgctctc
    16921 ttacaagacc ataaaaagtt aggcaagact attgtactca aagtgcgtta tgctgatttt
    16981 accaccttga caaaacgtgt caccttgcca gaattaacca gaaatgccgc acaaattgag
    17041 caagtagctg gggatatttt tgacagctta agcgaaaatc ctgctggtat ccgcctgtta
    17101 gggataacca tgaccaattt ggaggataag gtagctgata tttccttgga cctataggag
    17161 aaagagtgct ctatccgtcc gcctcatttt ggagaaaaaa gaagctgatt agggatttcc
    17221 ctaatcagct tctttggtcc attattttat tacagcatag cttggtctgt atcatcacct
    17281 ttttcgttaa gggttttagc cttgtaaaaa gcaaagccat aaagagcagc ttgtataagg
    17341 ataaggatag ttccaaccat tgacatggtt gttgtgaact ggttaaccaa gccgataaca
    17401 gaaaggataa ggcctaagat ataaggaata taactaaccg ttagaccttg ttttaattta
    17461 gataagtttt gagcacaaaa gacaatgata gcaataatag caaggacatt taagatagat
    17521 aagaaaatca taaatggtgt catgctgctt tgtagctgtg ccaattgctc agttgttaat
    17581 tgggcccgaa atgcttcatt cttgagttgg ctttgtaagt agaaaatccc tgcaaatccc
    17641 attaatgaca gtacaactcc aagcccgttt agaataataa tggcaatagt agacgttttg
    17701 agtgcctgac gcactttttc ataagaaatc atataatcct cctagagttc ttaatccgaa
    17761 attgtacaat gtgtttaata caaaaatatt ataccataga ttaatcaaaa atgtccgttt
    17821 ttctaggatt ttttctggaa aaagagggca atatctgact ctgtaagccc tatcatcgaa
    17881 tcgatagtcg aataattctc aggtgttaac ctaaaatcat cattatctga ctgagagttc
    17941 tcagtggggt tagagtttgt tgattgagag gaggctaagt cggattgttc ttggaagcgt
    18001 tcgatcaagt aggtttggcg tttatcgcct tcgtgtttaa tagcatactc aaaggcagta
    18061 tattctccca acagaattaa cttactttta gaccgagtaa tggccgtgta aatcacattt
    18121 cgttgcaaga gtcggccgct ttggcgtgtg ataggtaaaa tcaccacttg aaactcactc
    18181 ccttgcgatt tatgaatgct catggcatag gccagggtta attttagcca ttcatttcta
    18241 gggtacgtga cttcgctacc gtcaaaatct aagattaatt cgtcttgctt agattcggtg
    18301 tatttagcag gaatcaaatc tgtaatataa ccaatatctc cgttaaagac attcaactga
    18361 gcatcgttga ctaagtgcag gactttatca cctttacgaa aatgcgtatc attgaacaga
    18421 aattctgttt gtccttgcaa gggattgaga agttcttgca tgagttgatt aagatgattg
    18481 atgccagctt gtcctttgta cataggcgct aaaatttgaa tttcctcagc agggatgcca
    18541 cttttaatag cagataggac aattttttga atcatgtcag ggataaaggc tgcttgggct
    18601 tcaaaataag aacggtcagc ttttttatca cgaaagtcag cagctaagat tcctcgacgc
    18661 atctggtctg ccaaattgac aatagtagat tcttgggatt gacgaaatat cttttgcaag
    18721 gcgatttggg gcaggctatt gacttttaaa agatctgaca ggacttgacc gggtccaacc
    18781 gaaggaagct ggtcactatc tccgacaata atcacttgag ttgttgaatt aatagctcct
    18841 aacaactggt tggcaagcca ggtatccacc attgaaaatt catcgacaat cagcaggtcg
    18901 cagtctagat aatcctccat ggcttggtaa tcgttgtcgc cattgaggcc taagtgcctg
    18961 tggatggttg cgctaggaag tccagtcaac tcattcatgc gacgtgcagc ccgacctgtt
    19021 ggagctgcta acaagatagg aaggtctttt ttatccaaat caatctgatg caggttcgcg
    19081 taagcctgca aaatgcctcg aataacagtt gtttttcctg ttccgggacc acctgttagg
    19141 agaaagacct tgctggttaa ggccttagta atggcttctt gctgcacttg gtcataggtg
    19201 atggcaaagt ctttttgaac ggcttggatg gttgtttgaa tggtatcatg actaaatgac
    19261 tgacttaaag gggtatctaa gagacgagag atgttgttag caatcccttc ttcagcaaaa
    19321 taaaggctag catcaaacag tttggtgtca ctgtttttga ttttgccctc tatgatcaac
    19381 tcgcttagtt gttcagccac agcagcagga tcacattcta cttgacgtgc atcttcaagg
    19441 agtgtaatgg caaagtctaa taattgtcgt gcttgaacat aagtatctcc tcgattgatg
    19501 gattcttcca agagacagtg aaggagggct gcacgaaaac gtttcggaga gccgctttca
    19561 atccctaagt tttcagcgag agcatctgcc attttaaacc caaaaccttg tagatcttcg
    19621 actaactgat agggattttc tttaacaagg tcaagagcct cttctttata cttttcaaac
    19681 gcttgaaagg caaaacggtt gctaaggcca agttcgacga gaccagcaat cagttgctct
    19741 gtgccgtaat tcaattttag tttagcgaca aaggcttgac gattagcctt agataggcca
    19801 gagatagttt ctaatttgct tgggtcttct aaaatatggt caatggtatt atgaccatat
    19861 agtgcaatga ttttctccgc tgttttttta ccaatcccct taaaatggtc gctagagaaa
    19921 taattaacca aaccagatga actaggtttg attttttggt aacggcttag tttgagttgc
    19981 tgtccatatt tagggtgctg ggtcaattct ccccaaaagg tgtagtcatc tccttcaata
    20041 atgtcagcca tcgttcctgt gataatgatt tcaaagtcgt caatgtcact gtctgtatcc
    20101 tcaatggcaa ggaggagaat cttaaagaaa ttagcctggt tttcaaaaat gatacgatca
    20161 acagtacctg taaaaacgta ttccatagta actctttcta tttatacaag ataactgaaa
    20221 acctgcccaa aggcaggttt tttctaatta aagacggtca ttttattgag tggccaaaaa
    20281 cgagctttca cttcaccgat aaggttttct tttttgaaac taccaacttc gcgactatcc
    20341 ctggaaacaa tacgatcatc accaagaaga aggtattctc cttttggaac actcatctca
    20401 aagcgtgttt gtccctcaga attagttgta aaagcatcag atgtttctgc taactgttgg
    20461 aatagggtat tataggcgta agttttttgg agtttatcgt ttttaaattg ttttagatac
    20521 tcagccaaat acggctcaac tgttttttta ccattaatat aaagtgtgtc atcattataa
    20581 gaaatggtat cgcctggcaa tccaataact ctttttacga tttctttctt ttgtccattt
    20641 tcttcttcct gagcaactac aatatcaaag cgatcaatcc tagcttgatt aaaaacgata
    20701 aggcgttcgc catgagctag agttgggtcc atagaatggc cgtctacttt aacagcctgc
    20761 cacaaaaaaa gacgagatag accaaagaga attaaaaaga gagtgaatgg gccccattct
    20821 ttaataaact gtttcatatg attcctttta tttagtgaga agcgcttgcg ctttgtgagt
    20881 gttggcgaag tgaagtttag cactatattc taagctagac ataccataag cggctaagag
    20941 ttggctagca actttatctg aagctgaacc agcaccgctt gggagttggt aacctaaatc
    21001 ttgacctaat tgatcgagat tgtctaaaaa tagatttcta gcaatgatag agctaacagc
    21061 cacagccaaa tagtgacttt ctgccttttc ttgaaaggtt agaggatttg ggaaatggtt
    21121 tttttccttt tttagatgct tttcataatt tgattggcta gtgaaagcat caataacaat
    21181 ttgtttaggt tgaatgcctt tttgtaacaa caaaaaaata gcttggttat gaagagcaac
    21241 tttgatagaa atggtattat atggtttact tttaccaacc aattcgttat attttttagg
    21301 tgataggaga agtgattgat gaggtatttg tttctctaac agaggcgcaa tctgttgaat
    21361 ggttttatcc gataattttt tagaatcatc aaccccaagc tttttcagga agggatgatc
    21421 tttaggatcg acaaaacttg ccacaacagc aatcccacca aaataagagc cattacccac
    21481 ctcatcactg ccgattatag gtatatcttg gctattgttg cttgcttcaa aaactgtctt
    21541 agctactgga agattaagct cttgagctaa agcatttgca ccgtttccct ggagaactaa
    21601 ttttccggat ttgtacagca aaacagtaac cccatttttt ttagcagcaa aggctacata
    21661 gatattttgg ctactgatgg tgtagggggc tagctgtttt tttaaatgtt tactcagtat
    21721 agcatctatt ttcaaaacta aggtattcat aataattatt ttaacataaa atagttgact
    21781 atggttaatt cataagttta tttaacaaag aaaacagaga ctcgaatgtt tagacgggtt
    21841 agggcaatgg tgttgactat tttacgaaag tttcatttta cggtataatg ctaatgaggt
    21901 gaccctatga aaagtattaa tcgctataaa ttcacctttg gtgaaaaaac attaacattg
    21961 acaactgaca aagacaatct ctttatggaa gaagttgagc gggtagctaa agaaaagtat
    22021 caggctctta aaaatcattt accagaagct gatgacgaga caatcgctat tttaatggct
    22081 atcaatacct tgtcaacaca attaagcaga gagattgcca ttgaaaaaat ggaagctgaa
    22141 attttagatt tacgtcaaaa aaccttggtt ggtcttcaag aaaaagctaa tcaaatagat
    22201 gtgaatgagg tttaatcatg ttatctttat tgatagtgct tgttttaact tggaattttt
    22261 atattggtta tagtagaggt attattcttc aatcgtttta tgtcttagga gccctacttt
    22321 ctcttttggt agctaatcga ttttatattg gattagccca taagctaacg ctttggattc
    22381 cttattctaa cccggtagaa ggaacatcag tctttttctt taaatcagtt gatatctttg
    22441 ttttagataa ggtttattat gcaggccttg ccttttttat cattttctta ttggggtatg
    22501 cactgagtcg ctttcttggg atttttgttc atttcctttt gctagattat tttgataacc
    22561 agtggacaaa atgtttgagt ggcggactag cgcttctagt atcgcttctt tttttgaaca
    22621 tgttactgtc tatttttgca acggtcccta tgcctttttt acagcactat ttgcactcta
    22681 gttttcttgc tcgtttggtg attgaacacc ttccaccatt gacaataatt attcaaaaat
    22741 tgtggattca agccattatt tgatatcgtt ttgtgactaa tataagaacc tggagtgagt
    22801 ttcaccttta ggttctttat ttacgagaaa ctgtttagaa ataaagagaa cgcatgggaa
    22861 cttagtgact ttcttgccac attttccatc attttaggta taatgaagag tatgaataac
    22921 aagattttag agcagttaga atttaacaaa gttaaggaat tgctattacc ttatctcaag
    22981 acagaacaat cacaagaaga attattagag ctggagccga tgacggaggc tcctaaaata
    23041 gaaaaaagtt ttaatgaaat ttctgacatg gaacagattt ttgttgaaca tcactcattt
    23101 ggcatagtca gcctaagttc aatctctgag agtttaaaac gcttagagct ttcagctgat
    23161 cttaatattc aagaactttt ggctatcaaa aaagttttac agagttcttc ggatatgatt
    23221 cacttttatt ctgatttgga taatgtttct ttccaatctt tggatcgttt gtttgaaaat
    23281 ttggaacaat tccctaatct gcaagggtct tttcaagcta tcaatgatgg tggtttttta
    23341 gaacattttg cgagtccaga attagagcgt atccgtcgtc aattaacaaa tagtgaacga
    23401 cgggttcgtc agattttaca ggatatgctt aaggaaaaag cagagctttt atcagagaat
    23461 ctaatcgcta gtcgtagtgg acgaagtgtc ctaccagtaa aaaatactta tcggaatcgt
    23521 atttctggtg tggttcatga catctcttct tcaggaagta ctgtttatat tgagcctcgt
    23581 gctgtagtta cactaaacga agagataact cagcttagag ctgacgaacg ccacgaagaa
    23641 ggtcgtattt tacacgcatt ttcagacttg ttaagacctc atgtcgccac tattagaaat
    23701 aatgcatgga ttcttgggca tcttgatttt gtaagggcta aatatctttt tatgtctgat
    23761 aataaggcga cgatacctaa gatctctgat gacagcacgt tagcattaat caatgttcgt
    23821 catcctcttt taagtaatcc tgtggctaat gacttacatt ttgatcacga tttaactgca
    23881 attgtcatca ctggtcccaa tactggtggt aagacgatta tgctaaaaac actcggttta
    23941 gcacaattaa tgggacagtc tggtttgcca gtattagcgg ataaaggtag taaaattgca
    24001 gtatttaaca atatctttgc agatattggc gatgagcaat ctattgaaca aagtctatca
    24061 actttttcta gtcatatgac gcacatagtc agtattttaa acgaggctga ccgcaatagt
    24121 ttagttctct ttgatgaact aggagcagga acggatcctc aagaaggtgc tagtttggct
    24181 atggctattt tagaacacct taggttaagt catatcaaaa cgatggcgac cacgcactat
    24241 ccagaattaa aagcttatgg gattgagaca aattttgtag agaatgcgag catggaattt
    24301 gatgccgaaa cgcttagccc cacgtatcgc tttatgcaag gagttcctgg acgatcaaat
    24361 gcatttgaaa ttgcttctcg ccttggttta gctccattta ttgttaaaca agctaagcag
    24421 atgacagatt ctgactcaga tgttaaccgt attattgaac agttagaggc acagacactt
    24481 gagacacgta gaagactgga tcatattaaa gaagttgaac aagaaaatct caaattcaat
    24541 cgtgcggtta agaaactcta taatgaattt tcacatgaac gcgataaaga gttagaaaaa
    24601 atctatcaag aagctcaaga aattgtagat atggctttga atgagagtga tactatctta
    24661 aaaaaactca atgataagag ccaattaaaa cctcacgaaa ttatagatgc taaggcacaa
    24721 ataaaaaaat tagcacctca agttgattta tcaaaaaata aagtcttaaa taaggctaaa
    24781 aaaatcaaag cagctcgtgc ccctagaatt ggtgatgata ttatagtgac tagttatgga
    24841 cagcgaggta ccttaactag tcaattaaaa gatggccgtt gggaagcaca agtgggaatt
    24901 atcaaaatga cattaacaca agatgaattt agcctcgtta gagtccaaga agaacagaaa
    24961 gtcaaaaata aacagattaa tgtggttaaa aaggctgata gttctggacc aagagctcga
    25021 cttgatctta gaggtaaaag atacgaagaa gcaatgcaag agttagatca ttttattgat
    25081 caagcattgc ttaacaatat gggacaagtt gatatcattc atggtattgg tacaggcgtt
    25141 attcgtgagg gagtgacaaa atatcttcgt cgtcataagc atgttaagca ttttgcttat
    25201 gcctcacaaa atgcaggggg atctggcgcc acaattgtaa cgttagggta aatgatggaa
    25261 tcatatgaac acttttatgc caaactatct caacctttta gaaaaaaacc acagttaata
    25321 attcttttaa atgttttact aaaaataatc acaggagtga tgtacatact ttatccatct
    25381 tttctgatat ttacgctttg gcaagggatg acatttcaat tatggttaag gttattaatt
    25441 attcctgctg ttggctttat agctttgtct tacattagga aacgctttga ttttccacga
    25501 ccgtatgaaa aatggaatat taaaccttta attgataagg atacaaaggg aaggtcaatg
    25561 cctagcagac atgttttttc agctacgatg attagtatgt gtttgttacg atattatgtt
    25621 tactttggaa tagtttgttt aatattatcg gttttattgg caatttgccg tgtgatagca
    25681 ggtattcact atcctaagga tgttattgta ggttacctta ttggcttgat gttagggctt
    25741 tgtttattga tttagcgagt tcgtagcaaa tagtttcaaa aacaactaaa ttcttgtaca
    25801 ataggcttat cattaagatg aaatggagaa aaaagatggc attagaagta acagatgcta
    25861 catttgtaga agaaactaaa gaaggtttag tactcattga tttttgggca acttggtgtg
    25921 gtccatgtcg tatgcaagca ccaatcttag aacagttatc tcaagaaatc gatgaagatg
    25981 aactcaaaat tttgaaaatg gatgttgatg aaaatccgga aactgctcgt cagtttggta
    26041 ttatgtcaat tccaacattg atgtttaaaa aagacggaga agtggttaaa caagttgcag
    26101 gtgttcatac taaagaccaa ctgaaagcta ttattgctga attgagttaa ctaaaataaa
    26161 gcccagcgtc acgctgagct ttattttatg acctactaac ttcaatggaa taaccatgta
    26221 aacataaaac gacttgcaaa agcaaaagca acagtaatga ggaaaaatac agtgacaata
    26281 aggggtttct gataaggaag ttttgctctt tcttctcgtt tttcgatttc gtctaataat
    26341 tttccatttg aaatagctag gatttcctta taaggttgca catcatattt tttcttaaaa
    26401 cgttccacac gattagcata agtcatagta attatcgata ataaaacaaa aatgccaagt
    26461 cctagccact ctaagaaata gacttaatgg ataacttgaa atcattaata gtatcatcaa
    26521 tgttaccatt actttggtat ctcgtttaaa attcttttta tcaacctgag tgatggtata
    26581 tttcattttc tcaatgtctc ctttaatgag ttggtctaag ctcacttgaa aaatttgact
    26641 taggagtaag aggctatgga tgtctgggta agttttgtca ttttcccagt tagatatgct
    26701 ctgacggctt acatagactt tctcggctaa tttttcttgc gagagcgctt gttgtttacg
    26761 gtagcgaata atttgctgac caatttccat aaatatcacc gaaaaacttt acagcggcgt
    26821 aaaggaattg taaacaaaaa gtgaaccgtt atagttcact tgcgattaag catttttctg
    26881 ctttaagtag gtctctagca ttttcttttg cggtgttgca aagggataca gagcaaagtc
    26941 ctcaattgct acccacttta ggtgaggagc attaggtaaa tctgttgctt tgaccacccc
    27001 ctctatgagt tctattgtcc acttctggtg actaaaagtg tgcttaatat ttggaaagtg
    27061 attatcagtc cattggggct ttaattgata ttctctttcg aaagtttcat tttgggtttg
    27121 ccagattatg gggttggatt gattgtcatc aaataaatct aattgttgag aaagaggtga
    27181 cgtttcgata ataggaaatg accaaaaacc tcctagaagt ctccctttag tatttttctc
    27241 cagtagatat tggccatttt ggttacgaat gacaaaagcc tgaattcgca ttggtttagg
    27301 ctttttcttt ggatttttta tggggtattt accataagta ccattcaaat aagcagcgtt
    27361 aaagaaacga atagggcttt catcaggcct aggtgtctta gcggattcga tgtctgtacc
    27421 tagatccata agtgcctggt taaaatcacc gggtctgtca gggtcaatta gtatttccat
    27481 aatagcttga aaaattttac gatttttagg gtcaccgata tcataattaa cttcaaacaa
    27541 acgagccatg acacgcatca cattgccatc aacagcaggc tctggtaagt tgaatgagat
    27601 gctggcgata gcacctgcag tataaggacc aatccctttt aatgaagcaa tatcatcata
    27661 agtgtgagga aatatgccac caaaatcaac catcacttgc tgtgcagcct tttgcatatt
    27721 acgcacccga gaataatagc ctagtccctc ccatgccttt agtaattgtt cttcaggagc
    27781 gtctgccaaa tcttttattt gaggaaacca ctctagaaaa cgtttataat aagggattac
    27841 cgtattaact tgtgtttgtt gcaacatgat ttcagaaacc caaatataat atggattagt
    27901 agttcttcgc caagggagat cacgtttttc ttggtcatac caccctaaaa gtgtgcgacg
    27961 aaaagaagcg attgtctcat tatcccacat attaatacca taatctttta attcaatcat
    28021 gttgttattg taacacagga gccttaaaaa gagtaaaaaa agattttagg tatttgcgaa
    28081 aaagaaaagg aaatattata ataatattag gtttacctca tctaaatgtt gatttagaat
    28141 aactgaaatt aacgatagaa gcagacaggt tttaatttgg aggggacatg ttccagaaat
    28201 taaagaatct tattgatcgg tattcgtggt tcgtttttat aatgatgatt cttgtgttat
    28261 ttcttaacta tatttatcca tttgatcctt ctttgagcgg actacagttg gaatggctga
    28321 tcatgacgca agtttttcct ggattaggta tcgtatgtgc catggttgct attattttta
    28381 aaaagtttaa cctttttgtt ttggccctaa ttttatattt tgcactttgg ttaaaacttt
    28441 tccttgcttt ttcttttttc acctattttt taggagtctg actaagtgcc aatttttaaa
    28501 actcgtgaaa ggaaatgttt gacaaaactt agtcaagtag aaaaagttcc ttgcttttaa
    28561 ttgactatta gtgtacaata agattctgtg agtacacctc acttactcac tccaaaagta
    28621 gtgagtcatt agaccaaaag gaggaaaata tcaatggcta aatacgaaat tctttatatc
    28681 attcgtccaa acattgaaga agaagctaaa aacgctttgg tagcacgctt tgactctatc
    28741 ttgactgaca acggtgcaac tgttgttgaa tcaaaagatt gggaaaaacg tcgtcttgca
    28801 tacgaaatca acgatttccg tgaaggactt taccacatcg ttaaccttga agcgactgac
    28861 gcagcagctc ttaacgagtt tgaccgtctt tcaaaaatca atggtgacat tcttcgtcac
    28921 atgatcgtta aacttgacgc ttaattccaa ctaagagggt agtttatgat taataatgta
    28981 gtactagttg gtcgtatgac caaggatgca gaacttcgtt acacaccaag tcaagtagct
    29041 gtggctacct tcacacttgc tgttaaccgt acctttaaaa gccaaaatgg tgaacgcgag
    29101 gcagatttca ttaactgtgt gatctggcgt caaccggctg aaaatttagc gaactgggct
    29161 aaaaaaggtg ccttgatcgg agttacgggt cgtattcaga cacgtaacta cgaaaaccaa
    29221 caaggacaac gtgtctatgt aacagaagtt gttgcagata atttccaaat gttggaaagt
    29281 cgtgctacac gtgaaggtgg ctcaactggc tcatttaatg gtggttttaa caataacact
    29341 tcatcatcaa acagttactc agcgcctgca caacaaacgc ctaactttgg aagagatgat
    29401 agcccatttg ggaactcaaa cccgatggat atctcagatg acgatcttcc attctagtca
    29461 gaatggattg aacgaatacg aaattatttg agttcgggct aaaaatttag aacttagaat
    29521 ttagatcaac tccctaggaa atcaagattt cttgccagtt ttctaaaatt cagtcgtttt
    29581 ttaagagccc ttaacatcat aatttataaa ggagaaaata catggctcaa caacgtcgtg
    29641 gcggattcaa acgccgtaaa aaagttgact tcatcgcagc taacaaaatt gaatatgttg
    29701 attacaaaga tactgagctt cttagccgtt tcgtttcaga acgtggaaaa attcttcctc
    29761 gtcgtgtaac aggaacttca gctaaaaacc aacgtaaagt aacaacagca atcaaacgtg
    29821 ctcgcgttat ggctcttatg ccttacgtaa acgaagacta ataaacaaac agtccatttc
    29881 ggactgtttt ttagttgact aggactagtc taggcgtata ggtgagtttt ttctaaaaga
    29941 gagaatgata gtaaacgaaa atccttgcgt agacagcaag gatgaaatga ttgttatttg
    30001 ttaacaggtg acatagtgtt ttgaatgttg tatttgcgtt gtaggtaata gcgtaaagca
    30061 agggaaatac caccaataat gagcaaggca agaggaggca actgtgggtt aagagaggtt
    30121 ggtaaaaagg cagtcgcaga gtacaaggca atccaaatca acatggctaa tgataaggct
    30181 gcgatgattt tgaaccaact tggacgaagg ctcttatctt ttccgagatg acggtaaata
    30241 aagtaataag tagcgtacat ggatgctcct ccaccaaaac caagtgccag taaggaaatc
    30301 aatcctgtaa ctgtagcgtt tgtgttgaag aaggtcatga tgccatttaa aagggcaaca
    30361 attccgatga atagcaaaga ggtatctagc cacatcaacc aaggattggt gtttttgtca
    30421 gtttctgctg ctttttgact agggtcttgg ctaaaagaag ctgcccaagc agtcggagtg
    30481 cctaatagat ttcgagcggt gacacctttt ttctggtttt ctagaatagc tggaatggct
    30541 tcttcgagaa tcagcttaat gtcttcatca gacttgccgt cttggattaa tttgttcgta
    30601 gcggtgtgga taaattcttg attttttttg gtaagttctt gtaattccat gggaatccct
    30661 tctttatatg ggttagttaa agtaagtcaa tgatattagc tagtgtcaaa tgagactttg
    30721 gagccagccg tttgacacag agttttgtca ggtgttaact acattctaca gcttgctcca
    30781 ctctagaacc atttttttct aataaagtaa attacaacaa aggaactaag tagcatagca
    30841 atcaaggtaa tataccaaaa agcatgttct aggccattta gtggtaacca gttgttttgg
    30901 aaattcatac cataggcgga gaaaatcaca gttggtatat ctaaagccat ggtcatcaag
    30961 gccagtgttt tcataatagt gttctggttg ttgttgataa tagaagcagt ggtttcagtc
    31021 atggcattca agacattttc ataaatgcca gccatctcaa tggcctgttg ggtttcaatc
    31081 aaggtatctt ctagcaaatc ctcgtcctca atgtatttct tgagagagct tgttgagctg
    31141 gataatttct tgacgatgcg ttcgttgaat ttcaaggaag cctttaagta gacaatggat
    31201 ttttcaagtt ccatcatgtc gataagttct tcatttcgag tagctgcttc aagctgagct
    31261 tccaaacgtt cgctttggcg atcaatggtc ctcaaggcag tcagaaagag ctcggcgttg
    31321 cgatatagaa tctgaaaaac aaaacgtgtc ttcatgaagg tatagaaatt tttgacccgg
    31381 cggttgtgaa aatgatcgaa aagggtcatg tcatgcagac aagttgtgat aacagcattt
    31441 tccgttacaa taatgcctaa aggcatagta atatagtaac ttttattgtt acgttcttcg
    31501 tatatcggga cgtctacgat aattagggta taatcatctt ctacggcaat acgtgaggtt
    31561 tcttccacgt ccaaaggggc gcgcaagtca gaaatatcaa tgttaaattg atcggcgatc
    31621 ttcatagact cttcttggga agggttaacc agtttaatcc aagctcctgg ctcgaatgtt
    31681 tctatttctt tgaattcaat tgccgatgaa agaaacattt gtttcatgac aagccctcct
    31741 ttttgatgat tgactggtag agattgacat caaaccttga taataaagcc ttctcaagga
    31801 ttttctgaaa aattctcaat acttatctat tataccaaaa ttcgcaaagt ttggggcaat
    31861 aggttatcag aaatttttgt tataatataa gaaagctcga tgaggagggt gcctttaggc
    31921 acattcaaga tgcaaaataa aataataatt catggggcaa gagcccacaa tttaaaaaat
    31981 attgacgtgg aaattccacg agacaaatta gttgtcgtga cagggttatc agggtcagga
    32041 aaatctagtc tagcctttga tactatttat gcggaagggc aacgtcgtta cgtagaaagt
    32101 ttatcagctt atgctagaca gttcttgggt aatatggaaa aaccagatgt ggattccatt
    32161 gacggtctta gccctgctat ttccattgat caaaaaacta ccagtaagaa cccccgctca
    32221 acggttggta cggttacgga aatcaatgat tatttacgtt tactatatgc gcgtgtgggc
    32281 acaccttact gtattaatgg gcatggggcc attacagcat cttctgcaga acaaattgta
    32341 gagcaggtct tagccctccc tgaacggaca cgcatgcaga ttttagcgcc tattgttcgc
    32401 cggaaaaaag gtcaacacaa aaccattttt gagaaaattc aaaaagatgg ttatgtccgt
    32461 gtgcgggttg acggggatat ttttgacgtg acagaagtgc cggagctgtc caaaagtaag
    32521 atgcacaaca tcgaggtggt tattgaccgt ctggttaata aggatggtat tcgtagccgt
    32581 ttatttgatt cggttgaagc agctttaagg ctgggagatg gctaccttat gattgacact
    32641 atggatggca atgaactgct cttttctgag cattattcct gtcctgtctg tgggtttacg
    32701 gttcctgaat tagaaccaag actcttctct tttaatgcgc cgttcggctc ttgtccgacc
    32761 tgtgatgggc taggcattaa gttggaagtg gatttggact tggttgttcc tgacccaagt
    32821 aagtctttga gagagggagc tttggcgcct tggaatccta tttcctccaa ttattaccca
    32881 accatgcttg agcaagctat ggcaagtttt ggggtggata tggatacacc ttttgaggcc
    32941 ttgactgagg aagaaagaga tttagtgctt tatggttcag gagatagaga atttcatttt
    33001 cactatgtga atgattttgg tggtgagcgt aacattgata ttccttttga aggtgttgtg
    33061 actaatgtta atcgtcgtta tcacgaaact aatagtgatt atacgcgcaa tgtgatgcgt
    33121 ggttatatga acgaattgac ctgtgcgact tgtcatggtt accgtttgaa tgaccaagcc
    33181 ttgtgtgtgc atgtgggtgg cgaagaagga cctcatattg gtcaaatttc agaattatcg
    33241 attgccgacc acttgcagtt gttggaagaa ttggaactca cagaaaatga aagtaccatt
    33301 gctaaaccga ttgtcaaaga aattcatgac cgcctgacct tcttaaataa tgtgggactg
    33361 aattatctga ccttgtcacg ggctgctggg actttatcag gtggtgaaag tcaacgaatc
    33421 aggttagcga cacaaattgg ttctaactta tcaggggtga tctatatctt ggatgagcct
    33481 tctattggat tgcaccaaag agacaatgac cgtttgatcg aaagcctgaa aaaaatgcgt
    33541 gatttgggta ataccttaat tgtggtagaa cacgatgaag acaccatgat gcaggcagac
    33601 tggctgattg atgtggggcc tggggcaggt gagttcggtg gagaaattat tgcctctgga
    33661 acgccgaaac aagtggctaa gaataaaaaa tccatcacgg gtcaatattt gtctggtaaa
    33721 aaattcattc cagtgccatt agagcgtcgt tctggtaatg ggcgattcat tgaaataaaa
    33781 ggagcagcgc agaataatct tcaaagcctc gacgtgagat tcccactggg taaatttatt
    33841 gcggtcacag gggtatcagg ctcagggaaa tcaaccttgg ttaatagtat tttgaaaaag
    33901 gctgtcgccc aaaaattaaa ccgtaatgct gataagcctg gtaaatatca ctctatttct
    33961 ggtattgaac atattgaacg cttgattgac attgaccaaa gtccgattgg aaggacgcca
    34021 cggtcaaatc cagccaccta tacgggtgtc tttgatgata ttcgagactt gtttgcccaa
    34081 accaacgaag ctaagattcg tggctacaaa aaaggccgtt tctcttttaa tgtcaaaggt
    34141 gggcgttgtg aggcttgttc aggtgatggg attatcaaaa tcgaaatgca ctttttgcca
    34201 gatgtttatg tgccttgtga ggtttgccac ggcagacggt ataattctga gacgcttgag
    34261 gtgcattata aagaaaaaaa tattgctgaa gtacttgaca tgactgtcga tgatgccttg
    34321 gtatttttct ctgctatccc taaaattgcc cgaaaaattc aaaccattaa ggatgttggt
    34381 ttgggttatg tgaccttggg tcaaccagct actactctat ctggaggaga agcgcagcgg
    34441 atgaaattag ctagtgaatt gcacaaacgc tcgacaggta agagcttgta tatcctagat
    34501 gagccaacga ctggtttaca cacagatgat attgcaaggc tattaaaagt tttggaacgc
    34561 tttgtagacg atggtaatac ggttcttgtg attgagcata atttggacgt tatcaaatct
    34621 gctgaccata ttattgactt aggaccagaa ggtggtgtcg gaggtggtca gattgttgcc
    34681 acggggacac cagaagaggt agctcaagtt aaagaaagct atactggtca ttatttgaaa
    34741 gtaaaactac aacaatagga ttaggagttc gtttgagctc ctttttaatc ttttaaatgc
    34801 tctcaaatca tggtaaactt aaagtagttt tttcatgcta caatattctc aaaagttacc
    34861 aaaggagttc gcgatgtcag gatttttaga gcaacgatta ggtcactgcc taaggcagat
    34921 ggcagagaag gggctagagg ctcttctagt cacccattta accaatagtt attacttgac
    34981 aggtttttct ggaactgcag caactgtttt gataacggcc aaacgtcgtg ttttgatcac
    35041 agattcacgt tataccttgc ttgctaaagc tagtgttgag ggatttgata ttatcgaaag
    35101 ccgcacgccg cttaaggttg tggcagaatt gttagaggct gatcaaatag attgccttgg
    35161 ttttgaggac caggtatcgt tttcttttta tcaggccatg caagcagaac tgtcaggaat
    35221 aaccttgctt gctcagtcag gttttgtgga gcatttacgt tttattaagg atacttctga
    35281 aattgatacc attgctaaag cgtgctcgat ctcagacaaa gcatttgaag atgctcttga
    35341 ttttattaaa ccagggacaa ccactgaacg tgacctggct aattttttag attttcgtat
    35401 gcgtcagtat ggtgccagcg gcacatcatt tgatatcatt gtagcttcag gctatcgctc
    35461 tgccatgcct catggacgcg ccagtgacaa ggttatccag aataaagaga gcttgaccat
    35521 ggactttggg tgttactaca atcactatgt tagtgatatg acgaggacca ttcatattgg
    35581 ccaagttact gatgaagaac gtgagattta tgctcttgtt cttgctgcta ataaggctct
    35641 cattgataaa gctagcgctg gtatgactta tagcgatttt gacggtattc cgcgccaact
    35701 catcactgag gctggttatg gtagtcactt cacacatggc attggtcatg gtatcgggct
    35761 tgacatccat gagaatccgt tttttggtaa atctgagcaa cttcttcaag caggaatggt
    35821 ggtaacagac gagccaggaa tctatctgga taataaatat ggcgtccgta ttgaagatga
    35881 cttggtcatc acagaaactg gctgtcaagt attgaccttg gcaccaaagg aactgattgt
    35941 gttgtaaatt atcttaggga aggattagaa ggacgaagca atgacaaatc gtttatcatg
    36001 gcaagattac tttatggcca atgcagagct tatttccaaa cgctctacct gtgaccgcgc
    36061 ctttgtggga gctgttttgg taaaggataa tcgtattatt gccacgggtt ataatggtgg
    36121 tgtttctgcc acagataatt gtaatgaagc gggccattat atggaagatg gacattgcat
    36181 caggacagtt catgctgaaa tgaatgcttt gattcaatgt gcgaaagaag ggatttcgac
    36241 tgacggaact gaaatttatg taacgcactt tccctgtatc aactgtacca aggctctgtt
    36301 gcaggctggg attaaaaaga ttacttacaa agcacattat cgtccgcacc cgtttgcgat
    36361 tgaactaatg gagaaaaagg gagttgcgta cgttcaacac gacgtgcctc acatcatttt
    36421 gggtggtaag gaaggaccta atggttagct tgggcgaatg gtcataaaag atttgagcct
    36481 agggcgcttt tgtggtaaaa tgaagtgata atattttagt aagaggtaaa taataatgat
    36541 tgaagcaagt aagcttaaag ccggtatgac attcgaatca gaagggaaat taattcgtgt
    36601 ccttgaagct agccaccata aaccaggtaa aggaaacaca attatgcgta tgaaattgcg
    36661 tgatgtgcgt acagggtcta cctttgacac aacttaccgt ccagatgaaa aatttgagca
    36721 agctatcatt gaaactgttc cagcacaata cctatataaa atggatgaca ctgcttactt
    36781 catgaatact gacacttacg atcagtacga aattccagtt gctaacgttg agcaagagtt
    36841 gctttacatt cttgaaaact cagacgttaa aatccaattc tatggaagcg aagtgattgg
    36901 agtgactgtt ccaacaaccg ttgaattgac tgttgccgaa acacaaccat ctatcaaagg
    36961 tgcaactgtc acaggttctg gtaaacctgc aactcttgaa acaggtcttg tggtcaacgt
    37021 tccagacttt atcgaagctg gtcaaaaact aatcatcaac actgcagaag gtacttacgt
    37081 ttctcgtgct taatcctttg tcagaacagg ttagtctaaa gaagagaaag gaaatgctat
    37141 gacaactgaa catatcggtg aaatcgttat ttcaccacga gtacttgagg ttattactgg
    37201 gattgctacc acacaagttg agggcgttca ttcccttcat aacaaaaaaa tggcagatag
    37261 ctttaacaaa gcaagtcttg gtaaaggggt ttatctccag acagaagaag atggaagtgt
    37321 tacagcagat atttatgttt acttgcaata tggagttaag gtcccgactg tatctatgaa
    37381 tattcaaaaa acagtcaaat ctgctgtgta cgatatggca gaagtgccta tttctgcagt
    37441 taatatccat gttgaaggta ttgttgcgga aaagacacca aaaccagatt tgaagtcact
    37501 ttttgatgag gatttcttgg atgactaaca gctttcaaaa ttcaagaaga gatttgcgtg
    37561 aacgtgcctt tcaggcttta tttaacatag agatgggagc tgagttattg gcagcttctc
    37621 agtttgccta tggttatgat aaagtaacag gggaggacgc tcaagtattg gagctgccga
    37681 tttttttatt aagtcttgtg acgggtgtca ataatcataa agaagagttg gataacttga
    37741 tatcaactca tttgaaaaaa ggttggtcgt tagaacgctt gacactaaca gacaaaacgt
    37801 tattacgact aggtcttttt gaaatcaagt attttgacga aacaccagac cgtgttgcac
    37861 taaacgaaat cattgaagta gctaaaaaat attctgatga aacctctgct aaatttatta
    37921 atggcttact tagccaatat gtctcggaag ctccttcagc aaataaatca taataagtcg
    37981 gagcaatctt aggattgtat ccgatttttt caatttatgt acgaatatta aaagacaaac
    38041 aagcatactc tcgcatctag cgagagtatg cttgtttgtc ttttaaagta attagtgatt
    38101 ggttatgttt tgtttaaata cttgctcctg gaagtagcgt aatcggtaaa atatagtctt
    38161 tacttgtttt ttctttttta atttttttga tgagtatttc gacactcaat ttagcaatct
    38221 catcaatagg ttgacgaatg gtcgctaatt gaggaacata ttgctggata aatgtcgttc
    38281 catcataacc tatgactttc atatcctctg gaatagtaat gtgaagttgt ttggctactt
    38341 tcataatgag gatagcagtt aaatcatcag aaacgaaaag gccatcaggt tttcgggttg
    38401 ccaaaatgga tttaatttcc atttcgcgtc taacaggaga taggttattt ggtaatttga
    38461 tgatttctgc acttcgtttg agctggtagt taaaccctag ctggcgcaac cctgtgggcg
    38521 aatcagaatt gtcattacct gtaatcatga caatgttttg acaaccgtgt ttttgcaaag
    38581 tttgtgcggc taatttacca ccttcaaaat tatctgaaga aataaccgga atatttggcg
    38641 ccagattacg gtcaaaagct acaataggag cttcgacacg ctcataatcc tcaattccca
    38701 aattatgact ggaagaaata atgccgtcca cttgattggc cgcaagcatt tctaagtatt
    38761 cgcgttcttt gacgggatta tgttcactat tgcaaataat agttttgtag ccctgtttaa
    38821 acaattcaat ttccaaatgt tcaattaatt cagcgtaaaa gatattgcta atgttgggga
    38881 agataagccc aatgagttgg gttgatttac cttgcaaact tctagcgaga ttgttaggct
    38941 tgtagcccaa ttcacgcatg gccttattca ccttattcac tgttttttgg gaaaggtagc
    39001 ctttttggtt gattactcgc gaaacagttg ttggactgac acccgccaag gctgccacgt
    39061 ctgttaattt tgcgaccact tgcctaatac ctcatttcat aataatgtcc aaaagcttgt
    39121 ccttctacta cttggatacc tgtttgtcct tgggttggga aaacacgact agttaggact
    39181 ttttgccctt ggttaataaa gatttcaaga atggaattgt ccacatagac attaagtgta
    39241 acatggcctt gtgggatttg gcaagagcgc accgtaccat agtcttgggc atattgaacc
    39301 cctgcccgac ttcggtcaat gcttaactgt ccttttgttg tatccacctt caatcttagg
    39361 ccattccctt tttggtcggc aaataggagc aggtcaagct ttttttggcc tggaatcgtc
    39421 aattccaatt cataacagtt agaactgtct attttattat gaaataattc tgctggccct
    39481 cgaagatttt gtagggctga aacaggtgtt tgatagagaa ttccgtcttt aatccttaat
    39541 tctttcacta aactaagagc tccttgatag tcataacgat ctgtcggata atcaatatct
    39601 ggtaacccaa tccaagacac ggctagaacc ctgccatctg gactactaaa ggcttgagtg
    39661 gcataagctt caaaaccaaa gtcaagattt tgaagggccc ccccacccag caattggcca
    39721 gtttctggat tgaagctttc aaaaatttta taggtattgg ggtagatatt ttgataatct
    39781 aaatcagctt tagccagtcc ttgtgggctg aaaatcaaaa caggcttgtc atcgacaaac
    39841 acaaggttgg ggcattcaat catgtattcc gtgccagaat cgtcaaagtc caaatcggct
    39901 ataaatcgcc agttgtccac atgattgtcc acagctttgt aaagtttgat ttttcctttg
    39961 ccatctaaac cttgggcgcc aataatagca tagaattgac cttgataaga aaaaagctga
    40021 ggatcccgaa aatgttctgt aacatcatcg ggctgttcaa tcaaaacctg tggtattttg
    40081 gaaatatttc cttgtttatc catccatgcg ccaacctgta atggtgttct gacccaattg
    40141 gcatcgcgaa cattaccagt gtaaaagagg aagagcttgt catcaatagc ataggcagaa
    40201 cctgagtaag ccccatgact atcgtgagcg tggtctggca gaaggcggct ccttgtttcc
    40261 gtaaaatgga cgaggtctgt ggatgtcatg tgtacccatt gtttcagacc atgcgcagcc
    40321 ccataaggcc agttttgata aaaaagatgg tagtgaccgt tgaaataaga aaacccattg
    40381 gggtcattga gtaatcctgt cttaggttcg acatgaaatt ggctgtgcca tggggattgg
    40441 gccatttttt cagtaatagc ttggtagtct tttgagctcc actctttgta agggcggtag
    40501 cgaatagctt gtggtagatc catcaaaatc tccttgtttt atagtcgtct tcaagaatat
    40561 actaaacgtt ttctgtttaa aaatcaagaa tttaaagcat ataaaataaa aatatgttaa
    40621 acgcttgaca taaaaaatat tagtgataaa atgatagtca agaagtgaag cggattcact
    40681 agcgttggtc atgcacattc ttagccacaa agctggcaga atggatgagg gactaacacc
    40741 aaatgaaaaa ggagactttt aggcatggat aatcgtcaga ttgcaactga agtgattgag
    40801 gctttaggtg gccgagaaaa tgtgagaagt gttgcccact gtgcaactcg ccttcgcgtg
    40861 atggttcatg atgaaggaaa gattgataag gaaaaagcag aagctattga caaggttaaa
    40921 ggagctttct ttaattctgg tcaatatcaa atgatttttg gaactggtac cgtcaataac
    40981 atttatgacg aagtcgttgc tcttggttta ccaacatcat caaccagtga gcaaaaggca
    41041 gaagcaggca aacaaggcaa tatcttccaa cgggcgattc gtacgtttgg agatgttttt
    41101 gttcccatta ttccagctat tgtagcaacg ggtctcttta tgggggttcg tggtttggtg
    41161 acccagccag ctattatgga tttatttggg gtgcatgagt acggggaaaa ttttctcatg
    41221 tacactcgta ttctaacgga tacagccttt gtctacttgc cagctttggt ggcttggtca
    41281 gcctttaggg tctttggggg taatcctatt atcggtattg ttttaggttt gatgctggtg
    41341 tccaatgaat tgcctaatgc ttgggtagtt gcctctggtg gagatgttaa gccgctaacc
    41401 ttctttggat ttgttcctgt tgttggttat caaggtaccg ttttacctgc cttctttgtt
    41461 ggtctggtag gagctaagtt ggagaaatgg ttgcacaaaa aggttccaga agctttagac
    41521 ttattggtca caccgttttt aacgtttgct attatgagta ccttgggact atttgtgatt
    41581 ggaccagttt tccattctct tgaaaacctt gttctggctg ggacacaggc cgtcttgcat
    41641 ttgccgtttg gcattgctgg tcttattgtt ggtggtatcc aacagttgat cgtcgttact
    41701 ggtattcacc atatctttaa cttcctagaa gcgcagctaa ttgccaatac cggaaaagat
    41761 cctttcaatg cttacctaac agcagcaaca gctgctcaag ctggagctac cttagctgtt
    41821 gctgttaaaa ccaaatcaac aaaactaaaa ggtctggcct ttccatcaac cttgtcagct
    41881 cttttaggga ttactgaacc agctattttt ggggtcaacc tccgttatcc aaaagtcttt
    41941 gtttcaggtc ttattggtgg tgccttaggt ggttgggtcg ctgggctctt tggcattgca
    42001 ggaactggtt ttgggattac ggtcttacca ggaactctcc tttacttgaa tggccattta
    42061 ttacaatacc ttgtgactat gcttgtcggt cttggggtag cctttggaat tgcttatact
    42121 tggggttatc aagatagaga aacccttccg ttaccagctg tcgaagttga tcaaacggct
    42181 gatcagccag ccttagcaga ggaaacttta tatagtcctt tgaatggaac agttgtagat
    42241 ttagcagctg tttcagaccc tgttttttca tcaggtgcta tgggtcaagg cttagcaatt
    42301 aagccagaag ataataccct atactcacca gttgatggta aagttgaaat tgtctttgaa
    42361 acaggtcatg cctatgctat aacgtcaagt caaggagcag aagtgttact tcatattggt
    42421 attgacactg tgtcgatggc aggagatggc tttgaatctc ttgtagcagt aggtcaggcg
    42481 gttaaaaaag gtgatcttct tggacacttt gatcctagca agattgcaga agctggacta
    42541 gatgacacca ccatgatgat tgtgaccaat agcgctgact atcaaagcgt ggacattctt
    42601 gctcaaggac atgttttgat tggtgatcaa gtggcactta tcaaataagg acaaaagagc
    42661 taactaagca gctcttttgt cctgccattc atggcaggtt ggcaaaaaaa tgagaaaagc
    42721 ctaaaaacct taaatttgtg ttattttacc tatactttgt accttgtttt ttttaataaa
    42781 gtgttgttat acttaaggcg aactatagga atgcgcttac atagatggta tatcaactgg
    42841 gaagccatga cttagtacca aaaataagga gtgtccaaat ggataaacat ttgttggtaa
    42901 aaagaacact agggtgtgtt tgtgctgcaa cgttgatggg agctgcctta gcgacccacc
    42961 atgattcact caatactgta aaagcggagg agaagactgt tcaggttcag aaagaattat
    43021 cttctataga tagcttgcat tatctgtcag agaatagcaa aaaagaattt aaagaagaac
    43081 tctcaaaagc ggggcaagaa tctcaaaagg tcaaagagat attagcaaaa gctcagcagg
    43141 cagataaaca agctcaagaa cttgccaaaa tgaaaattcc tgagaaaata ccgatgaaac
    43201 cgttacatgg tcctctctac ggtggttact ttagaacttg gcatgacaaa acatcagatc
    43261 caacagaaaa agacaaagtt aactcgatgg gagagcttcc taaagaagta gatctagcct
    43321 ttattttcca cgattggaca aaagattata gccttttttg gaaagaattg gccaccaaac
    43381 atgtgccaaa gttaaacaag caagggacac gtgtcattcg taccattcca tggcgtttcc
    43441 tagctggagg tgataacagt ggtattgcag aagataccag taaataccca aatacaccag
    43501 agggaaataa agctttagcc aaagctattg ttgatgaata tgtttataaa tacaaccttg
    43561 atggcttaga tgtggatgtt gaacatgata gtatcccgaa agtaaatgga gaagctagtg
    43621 acgaaaatct caagcgatct attgatgttt ttgaagagat tgggaaatta attggaccaa
    43681 aaggtgctga taaatcgcgt ctgtttatta tggatagcac ctacatggct gataaaaacc
    43741 cattgattga gcgaggagct ccttatattg atttgttatt ggtacaagtc tatggcgcaa
    43801 gaggagaaca aggtgagttt caaaacgata ccaagttagt tacagatacc cctgaagaac
    43861 gatggcaagg ttatagcaag tatattcgtc ctgaacaata catgattggt ttttctttct
    43921 atgaggaaag agcaggcagc ggcaatcttt ggtatgatat taattctcgc aaggacgagg
    43981 acaaagcaaa tggaattaac actgacataa ctggaacgcg tgccgaacgg tatgcaaggt
    44041 ggcaacctaa aacaggtggg gttaagggag gaatcttctc ctatgctgtg gatcgtgatg
    44101 gtgtagctca tcaacccaaa caaatagctg aaaaagataa acagaatgta aaaaataatc
    44161 aacctcagat tccagagatt actgataaca ttttccactc agattatagt gtctccaagg
    44221 cactaaagac agttatgcta aaagataagt cgtatgatct gattgatgag aaagatttcc
    44281 cagataaggc tttgcgagaa gctgtgatgg cgcaggttgg aaccagaaaa ggtgatttgg
    44341 aacgtttcaa tggcatatta cgattggata atccagcgat tcaaagttta gaaggtctaa
    44401 ataaatttaa aaaattagct caattagact tgattggctt atctcgcatt acaaagctcg
    44461 accaatctgt tttacccgct aatatgaagc caggcaaaga taccttggaa acagttcttg
    44521 aaacctataa aaaggataac aaagaagaac ctgctactat cccaccagta tctttgaagg
    44581 tttctggttt aactggtctg aaagaattag atttgtcagg ttttgaccgt gaaaccttgg
    44641 ctggtcttga tgtcgctact ctaacgtctt tagaaaaagt tgatatttct ggcaacaaac
    44701 ttgatttggc tccaggaaca gaaaatcgac aaatttttga tactatgcta tcaactgtca
    44761 gcaatcatgt tggaagcaat gaacaaacag tgaaatttga caagcaaaaa ccaactgggc
    44821 attacccaga tacctatggc aaaactagtc tgcgcttacc agtggcaaat ggaaaagttg
    44881 atttgcaaag ccagcttttg tttgggactg tgacgaatca aggaacccta atcaatagcg
    44941 aagcagacta taaggcttac caaaatcagc agattgctgg acgtagcttt gttgattcaa
    45001 actatcatta caataacttt aaagtttctt atgagaacta taccgttaaa gtaactgatt
    45061 ccacattggg aaccactact gacaaaacgc tagcgactga taaagaagag acctataagg
    45121 ttgacttctt tagcccagca gataagacaa aagctgttca tactgctaaa gtgattgttg
    45181 gtgacgaaaa aaccatgatg gttaatttgg cagaaggcgc aacagttatt ggaggaagcg
    45241 ctgatcctgt aaatgcaaga aaggtatttg atgggcaact gggcagtgag actgataata
    45301 tctctttagg atgggattct aagcaaagta ttatatttaa attgaaagaa gatggattaa
    45361 taaagtattg gcgtttcttc aatgattcag cccgaaatcc taagacaacc aataaaccta
    45421 ttcaggaagc aagtctgcaa atttttaata tcaaagatta taatctagat aatttgttgg
    45481 aaaatcccaa taaatttgat gatgaaaaat attggattac tgtagatact tacagtgcac
    45541 aaggagagag agctactgca ttcagtaata cattaaataa tattactagt aaatattggc
    45601 gagttgtctt tgatactaaa ggagatagat atagttcgcc agtagtccct gaactccaaa
    45661 ttttaggtta tccgttacct aacgccgaca ctatcatgaa aacagtaact attgctaaag
    45721 gtctatctca acaaaaagat aagttttctc aaaagatgct tgatgagtta aaaataaaag
    45781 agatggcttt agaaacttct ttgaacagta agatttttga tgtaactgct attaatgcta
    45841 atgctggagt tttgaaagat tgtattgaaa aaaggcagct gctaaaaaaa taaacaaagc
    45901 aactttctta gatagcaaca ttcagattaa attaacaaaa tgtgactatg ataaaggttt
    45961 gctggaattg attaaccaaa agactaaaaa tctgagatga atagtcccag atttttagtc
    46021 ttttataggt tttgatgaca taaagctaaa taatcgttag actaccagaa agtggcactt
    46081 gtccgtgaga catggctgtc ttgataagag cctgtgtcat cataaagata aaaaagaaca
    46141 agaaaaagga gaaaacatgg gaaaattata tggaagcatt gaagctggtg ggacaaagtt
    46201 tgtctgtgcc gtgggtgatg aggagtttac agtggtggat aaaacacaat ttctgaccac
    46261 cacaccagaa gaaaccatcg cgcgaaccat cgcttatttt aaagcttttg aggcagattt
    46321 ggctggaatg gcgattggtt cttttggacc aattgatatt gatccgtcgt cagagactta
    46381 cggtcatatc acaaccactc ctaagtcagg ctgggctaat gtggatttgt taggacaact
    46441 ttcggctgct tttaagattc cttttgatgt gacaacagat gttaatagct ctgcttatgg
    46501 tgaggtgctt gctcgtcctg gtgtggaaag tttggtctat tacaccatag gtactggtat
    46561 tggggcggga gctattcaac atggccactt tattggggga ttaggtcata cagaagcggg
    46621 tcatacctat gtcatgcccc atcctgatga tatggccaag ggatttttag gtgtttgccc
    46681 ttttcataaa gggtgtctgg aagggatggc agcaggtcca agtattgagg ccagaacggg
    46741 agtgagaggt gaacggcttg atcaggaagc tgatgtttgg gacattcaag ccttctacat
    46801 tgcccaagca gcgctgcaag caactatgct ttaccgtcct caagtgattg tttttggcgg
    46861 aggtgtcatg acgcaagaac atatggtgtt gcgcgtgcat gataaattca ctaccctttt
    46921 aagcggttat ttgccagtcc ctgatttgac agactacatt gttactccag ctgttgctga
    46981 taatggctcc gctactctgg gaaattttgc tttggccaag ttggctgcac aaggaaaata
    47041 gggtctgttt ttgcctgctt gtctagtaaa agaaagcgca gtcagctaga acatgctata
    47101 ataaacagag attaacatca gaagcgagga atattatgtc agaaccatta tttctaaaat
    47161 caaccatgca cgacagaatt tggggtggca ccaagttgag agatgtcttt gcttacaaca
    47221 tcccaagtga caccacaggt gagtattggg ctatttctgc tcatcctaat ggtgtttcga
    47281 cagttactaa tggacgttat caaggacaac ctttaaatac attatatgcg caagagccgg
    47341 ccttgtttgg gaatccaaag gaagaagttt ttccactgtt aactaagatt ttagatgcta
    47401 atgactggct aagtgtccaa gttcatcctg atgatgctta tggacgtgaa catgaaggag
    47461 aattaggcaa gacagaatgc tggtatatta tttctgccga agaaggttct gaaattgtat
    47521 acggccatca ggccaagtcc aaagaagacc ttcgtgccat gattgaagca ggcgcttggg
    47581 atgatttgct gactcgtgtc ccagtcaaag caggcgattt tttctatgtt ccaagtggga
    47641 ccatgcatgc gatcggcaag ggaattctta ttttagaaac ccagcagtca tctgatacca
    47701 cttatcgggt ttatgatttt gaccgtaagg acgttaatgg taatcttcgt gaccttcata
    47761 ttgaaaagtc tattgatgtc ttaacgattg gtaagccaga aaatagcgtg ccagccacta
    47821 tagttttgga taatatggta gaaacaactt tagtctcaac gccatttttc actgtttaca
    47881 aatgggtaac tagtcaaatg gttgacatga aacaagctgc gccttatctt ttagtgagtg
    47941 ttttaaaagg tcaaggaaaa ctctatgtgg accagaaggc ttatgagcta gaaaaaggca
    48001 tgcactttat cttgcctaac gatgttaaat cgtggtcatt tgatggtcaa ttagaaatga
    48061 ttgtgagtca ccccaatcaa ctcgtttaat accatggtat caatgtgaga aaaaaggata
    48121 aaattatgac tctctgtttc tctgataact ttaccaacct ttcttgaact gcctacatat
    48181 ttatgttaaa atgaaatgat tagatgatcg aaaggaaaga gaatggccaa tattctacgc
    48241 aaagttatcg aaaatgacaa aggcgaacta agaaaattag aaaaaattgc aaaaaaagta
    48301 gaatcctacg cagaccaaat ggtgtcattg tcggatagag atctacaagg aaaaacactt
    48361 gaatttaaag aacgctatca aaaaggtgag accctcgaac aactattacc tgaggctttc
    48421 gcagttgttc gtgaagcagc aaaacgtgtg ttgggcttgt tcccttatcg tgttcaaatt
    48481 atgggaggaa ttgttcttca taacggggat gtccctgaaa tgcgtactgg tgaaggaaaa
    48541 actcttacag ccaccatgcc agtttatctc aatgctattg ctggtgaggg tgttcacgtt
    48601 attactgtta atgagtatct ttcaacgcgt gacgctaccg aaatgggtga agtgtatagc
    48661 tggttaggtc tttcagttgg gatcaaccta gctgctaagt ctcctgctga aaaacgtgaa
    48721 gcttataatt gtgatattac ttattcaacc aactctgaag tcggttttga ttaccttcgt
    48781 gacaacatgg ttgttcgcca ggaagacatg gtacaacgcc cactcaattt tgccttggtt
    48841 gatgaagtgg actcagtctt aattgacgag gcaaggacac ctttaattgt ctctggtgct
    48901 gttagctctg aaaccaatca attgtatatt cgtgctgaca tgtttgtaaa aactctgacg
    48961 tcagtggatt atgttattga tgtgcccact aaaacgattg gattaagcga ttcaggtatt
    49021 gataaagctg agagttattt taacttgagc aatctttacg atattgaaaa tgtagccttg
    49081 actcacttta tagacaacgc ccttcgtgca aactatatta tgttgttaga tatcgattat
    49141 gtggtcagcg aggatggtga gattcttatt gttgaccaat ttacaggtcg tacgatggaa
    49201 gggcgtcgct tctcagacgg cttgcaccaa gctattgagg caaaagaagg cgttcgtatt
    49261 caggaagaat caaaaaccag cgcctcaatc acctaccaaa atatgtttcg tatgtacaaa
    49321 aaattggcag gtatgactgg tactgcgaag accgaggaag aagaatttcg cgaagtttat
    49381 aacatgcgta ttattccaat tccaaccaat cgtccaattg cccgtattga tcacactgat
    49441 ttgctttacc cgaccttaga atcaaagttt agagcagttg tggaagacgt taaaacgcgt
    49501 catgcaaaag gacaacctat ccttgtaggt acggttgctg ttgaaactag tgatttgatt
    49561 tcacgcaagc tggttgaagc agggattcct catgaggttt tgaatgctaa aaatcacttt
    49621 aaagaagctc aaatcattat gaatgctggg caacgtggtg ctgttacaat cgcaactaac
    49681 atggctggtc gtggtactga tatcaagctt ggtgaaggtg ttcgtgaact tggtgggtta
    49741 tgtgtcattg gtacagagcg tcatgaaagc cgtcgtatcg ataaccagct tcgtggacgt
    49801 tcaggtcgtc aaggagatcc aggtgaatcc caattctatc tttcattaga agatgatttg
    49861 atgagacgtt tcggctctga tcgtataaaa gcctttttgg atcggatgaa attagatgaa
    49921 gaagacactg ttattaaatc aggtatgtta gggcgtcaag tggaatctgc tcaaaaacgg
    49981 gttgaaggaa ataactacga tacccgtaaa caggtcttac aatatgatga tgtgatgcgt
    50041 gaacagcgtg aaattatcta tgctaaccgt cgtgatgtca taactgctaa tcgagatctt
    50101 ggcccagaaa ttaaagctat gatcaagcgt actatcgacc gtgctgtaga tgctcatgca
    50161 cgtagcaatc gtaaagatgc tatagatgct attgtaactt ttgctaggac ctcgctggta
    50221 ccagaagagt ctattagtgc taaagagtta cgtggtttaa aagatgatca aatcaaagag
    50281 aagctttatc aaagagcgct tgctatctac gaccagcaac tatcaaaact tcgtgatcaa
    50341 gaagctatta ttgaattcca aaaagtactc attttgatga ttgtggataa caaatggact
    50401 gaacacattg atgccttaga tcaacttcgt aatgctgttg gacttcgggg gtatgctcaa
    50461 aataaccctg tggtggaata ccaagcagaa ggtttcaaga tgttccaaga tatgattggt
    50521 gctatcgagt ttgatgtaac acgtaccatg atgaaagcac aaattcacga acaagaacgt
    50581 gaacgtgcaa gtcaacgtgc cacaacagca gcacctcaaa acatccaatc gcagcagtca
    50641 gctaacaccg atgatttacc caaagtggag cgtaacgaag cttgtccatg tggttcaggc
    50701 aaaaaattca aaaattgtca cggtcgtaaa tccttctcat aagaacgaga cacaacagga
    50761 caaagttagg tatatagaaa gaagctgaga ataattctca gcttctcact gtttaaatct
    50821 tctaacatta agatgaaata aggtttggtg gaaagtaatg attgttggac atggaataga
    50881 cttacaagag atttcagcta ttgaaaaagt ttatcaaaga aatcctcgct ttgctcaaaa
    50941 aattttaact gagcaggaat tggctatttt tgagagtttt ccttataaac gtcgactcag
    51001 ctatttggcg ggtcgttggg caggcaaaga ggcttttgct aaggctatag ggacaggtat
    51061 tgggcggtta acctttcaag atattgagat tttaaatgat gttagaggat gtcccattct
    51121 gacaaaatct ccgtttaaag gaaatagttt tattagcatc tcacatagtg gcaattatgt
    51181 acaggctagt gttattttgg aggataaaaa atgatttcaa gtttccatcg cccaacagtt
    51241 gcaagggtca acttacaagc tattaaggag aatgttgcca gtgttcaaaa gcatattcca
    51301 ctaggggtaa aaacgtatgc agttgtcaag gctgatgctt atggtcatgg tgctgtccag
    51361 gtgtcaaaag cactcctacc tcaagtggat gggtactgtg tgtcaaatct tgatgaggct
    51421 ttgcaattac gtcaagcagg cattgataaa gagattttaa ttcttggagt cctcctgcca
    51481 aatgaattag agttagcagt tgctaatgct attactgtta caatcgctag tttagactgg
    51541 atagctttag ctagactgga gaaaaaagaa tgtcaaggct taaaagttca tgtaaaagtt
    51601 gattctggta tggggcggat cgggcttcgt tcttcaaaag cagtcaattt attgattgat
    51661 agtctaaaag agttgggtgc tgatgtagaa ggtattttca ctcattttgc cacagctgat
    51721 gaggcagatg atactaaatt taaccagcag ttacagtttt ttaaaaagct gatagctgga
    51781 cttgaggata agcctcgttt agtacatgct agtaattcag ccacaagtat ctggcatagt
    51841 gataccattt ttaatgctgt tcgtttagga attgttagtt atggtttgaa tccaagtggt
    51901 tctgatctaa gcttaccatt tccactgcaa gaggctttat ctctagaatc tagcttagtg
    51961 catgtcaaga tgatttcagc tggtgataca gtcggttatg gagctactta tactgccaaa
    52021 aagtctgaat atgtagggac cgtcccaatc ggttatgcag atggctggac caggaacatg
    52081 caaggctttt cggtgttagt tgatggacaa ttctgtgaaa ttatagggcg tgtatcgatg
    52141 gatcaactga ccatacgact tcccaaagca tatcctttag gaacaaaagt cactttgatt
    52201 ggcagcaatc agcaaaaaaa tatttctaca acagatatcg caaattaccg taatacaatc
    52261 aattatgaag ttctatgcct tttaagtgac cgtattcctc ggatatatta agaaaatcac
    52321 gtaaaaataa ttgcattgtg cttatcttta atgttataat aaagtgagga cattagaaag
    52381 aagtgactaa ttaatatatg aataaaaaca aactattaag agttgccatg ctactaagtc
    52441 tcttagcccc gacagcagaa agcatgacag tgttggctca agatgtaatg cttgagacgc
    52501 ataaagcaac tacaaatgaa accagtgatt cttcttcaaa agaggaaaat aataaaaatg
    52561 cagcacctac aacatcagat aaaactgacc aaggtcccct tgatgcttct gcagaaacaa
    52621 actctaatag tcttgttaac gcggatgata aaaaaagaag cgattctagt cagtctgctg
    52681 taggctcttc gaacaacaag gcagaagcag aaaaccaggt agatgataaa tcaactgatc
    52741 attcgaaacc aactgaccag ccaaaaccga ctgatcagcc caaaccatca ccatctaaag
    52801 ttgatacggc acctgcttct tcattgtcga gacagctgcc agaggcaaga actcctattc
    52861 agtcgttgtc cccttacgta tcagatttag atttgagtga gatagatatc ccttctgtca
    52921 acacatacgc ggcatatgta gagcattgga gtggtaaaaa tgcctatacc catcatcttt
    52981 tatctcgccg ttatggtatt aaagctgacc agattgatag ttacttaaaa tcaacaggca
    53041 ttgcctatga cagcacacgt attaatggtg agaagctatt gcaatgggaa aagaaaagtg
    53101 ggctggatgt tcgagctatc gtagctattg cgatgtctga gagttcttta ggaactcaag
    53161 ggattgcgac tttgcttgga gctaatatgt ttggctatgc agcttttgat ctagatccga
    53221 ctcaagcaag taagtttaat gatgatagtg ctattgtcaa aatgacacaa gataccatta
    53281 ttaaaaacaa aaatagcaat tttgcacttc aagatttaaa agcggctaag ttttcacgag
    53341 gtcaattaaa ctttgcaagt gacgggggtg tttattttac tgatactact ggtagtggta
    53401 aacgtcgcgc acaaattatg gaagacctgg ataagtggat tgatgaccat ggtggcacac
    53461 cagccattcc agccgaattg aaagtgcagt catcagctag ttttgcatct gtgccagcag
    53521 gttataagct ctctaagagt tatgatgtct tgggttatca agcttcgagt tatgcttggg
    53581 gacaatgcac ttggtatgtg tataatcgcg ccaaagaatt gggttaccaa tttgatcctt
    53641 ttatgggaaa tggtggagat tggaagtata aagcagggta tgccctgtca aagactccaa
    53701 aagtaggtta tgctatttca tttgcaccag ggcaagcagg cgctgatggc acttatggcc
    53761 acgtatcaat tgtagaagat gttagaaaag atgggtctat tcttatttca gagtctaact
    53821 gtatcggctt aggtaagatt tcttatcgta cctttacagc tcagcaggct gaacagctaa
    53881 catatgttat tggcaagagt aaaaactaat aactaatgac ttttcttaag gcttaatttt
    53941 cttagcggga gttaggcctt ttaaactgtt ggtgtaacac gataaagttt caagtaaata
    54001 aatgattttg agacaatagc acgattaggg ctattgtctt tttttattgt gatgaatatg
    54061 cagtagtgac atctcatgtt gtctcctaac acaattatgg agcttataac gtgttacatg
    54121 ttttgtgaat gaagtaatga ttgaatcagc cctagtaata actatcctaa ggctagcttt
    54181 atctcagtaa tattgttgta gaggaattct tttatcagag atatcatcat tatcaatcca
    54241 ggcttattgc tagtgtcttg gctcacatag tggagctttt taacagacaa ttggaccatt
    54301 ggaaacaatc ttgacaaaat aatcacaaag tgatagatta agttcagtta ataaaaaagt
    54361 tagcttattc ataaaaattt ttagaaagtt gattgaaaat gaaaaaaatc agcaaatgtg
    54421 cgtttgtggc aatatctgcc cttgttctca ttcaggctac tcaaactgta aaatcacaag
    54481 agcctttagt tcagtcacaa ctcgtgacaa cagtagcttt aactcaggat aatcgacttt
    54541 tagttgaaga gataggccct tacgctagtc aatcagctgg aaaagagtat tataaacata
    54601 ttgaaaaggt tattgttgat aatgatgtct atgaaaaaag cctggaaggc gagcgaacct
    54661 ttgatattaa ctaccaaggg attaagatca atgctaacct tattaaagac ggtaagcatg
    54721 aattgactat tgttaataaa aaagatggtg atatcctaat tacctttatt aaaaagggcg
    54781 ataaagtgac ctttatttca gctcaaaaat taggaacaac agatcatcag gattcattaa
    54841 aaaaagatgt gctcagtgat aaaacagtgc cacaaaacca aggcacacaa aaagttgtta
    54901 aatctgggaa aaatactgct aacttgtcat taataacaaa attgagtcaa gaagatggtg
    54961 caattttatt tccagaaatt gatcgttatt ctgataacaa acagataaaa gcattgactc
    55021 agcaaatcac aaaggttaca gtcaatggta cagtttataa agatcttatt tcagattctg
    55081 taaaagatac taatggctgg gtctcgaata tgacagggct tcatcttgga acaaaagctt
    55141 tcaaagatgg agaaaataca atcgtgatat cctcaaaagg atttgaagac gttaccatta
    55201 ccgttaccaa gaaagatggt caaatccatt ttgtatctgc caaacaaaaa caacatgtga
    55261 ctgctgaaga cagacaatca acaaagttgg atgtcaccac tttgaaaaaa gctatcaaag
    55321 aagcggatgc gattattgct aaagaaagca acaaagacgc ggtcaaagat ctggctgaga
    55381 aacttcaagt catcaaggat tcttacaaag aaatcaaaga tagtaagcta ctcgccgata
    55441 ctcatcgact gttaaaagat accatcgagt cttatcaagc aggtgaggtt tctattaaca
    55501 atctcacaga aggaacctat acgctaaact ttaaagctaa taaagaaaac tcagaagagt
    55561 cctccatgct tcaaggtgct tttgataaaa gagccaaatt agtggttaaa gcagatggta
    55621 caatggaaat ttccatgctt aatactgctt taggacaatt tttgattgac ttttctattg
    55681 aaagcaaagg gacctaccca gcagcagtgc gtaaacaagt tggccaaaaa gatatcaatg
    55741 gtagctatat tcgaagcgaa tttaccatgc ctattgatga tttggataaa ttacacaaag
    55801 gtgctgtttt ggtatcagcc atgggaggtc aagaaagtga tttaaaccac tatgacaaat
    55861 acaccaaact tgacatgacc tttagtaaga ccgttaccaa aggctggagt ggttatcagg
    55921 tagaaactga tgataaagaa aaaggggttg ggactgaacg tcttgaaaaa gttttagtta
    55981 aacttggcaa agatttagac ggcgatggta aattatcaaa aacggaatta gaacagattc
    56041 gaggcgagtt gcgtctagac cattacgagt taactgatat ttctttattg aaacatgcta
    56101 aaaatattac agaactacat ctggatggaa accaaattac ggaaattcca aaagagttat
    56161 ttagtcaaat gaagcaactt cgatttctta acttaagaag taatcattta acttatctag
    56221 acaaagatac atttaaaagc aacgctcaat taagagaact ctacttatca agtaacttta
    56281 ttcactctct tgaaggagga ctattccagt cgcttcatca cctggagcaa cttgatcttt
    56341 ccaagaatcg tattggccga ctttgtgata acccatttga aggattgtct cgcctgactt
    56401 cattaggttt cgcagaaaat agtcttgagg agatacctga aaaagcgcta gagcctctaa
    56461 catcacttaa ctttatcgac ttatctcaaa ataatttagc actactgcca aaaacaatag
    56521 aaaaattgcg cgccttaagc actattgtgg caagtagaaa tcatattact cgtattgata
    56581 atatttcatt taaaaatctt cctaaattat ctgtactcga tttatcaact aatgaaattt
    56641 caaatcttcc aaatggtata tttaaacaga ataaccaatt aacaaaactt gattttttca
    56701 ataacttgct tactcaggtt gaagaatcag tatttccaga tgttgaaacg cttaatttag
    56761 atgtgaagtt caatcagata aaaagtgtga gtccaaaagt aagagctctt atcggacaac
    56821 acaaactgac tccacaaaaa catattgcaa aacttgaagc ttccttagat ggcgaaaaaa
    56881 taaaatatca tcaagctttc agtcttttag atttgtatta ttgggagcaa aaaacaaatt
    56941 ctgccattga taaagaacta gtgtctattg aagaatatca acaattgtta caagaaaaag
    57001 gttcagatac tgtctcttta cttaatgata tgcaagtcga ttggagtatt gtgattcagt
    57061 tgcaaaaaaa agcttccaac ggacagtatg tgacggttga cgaaaagctt ctctcaaatg
    57121 atccgaaaga tgacttaacg ggagagtttt ctttaaaaga tccaggtaca tatcggattc
    57181 gcaaagcttt aataacaaag aaatttgcta ctcaaaaaga acatatctat ttgacatcta
    57241 atgatatcct tgtggcgaaa ggaccacatt cacatcaaaa agatttagtt gagaaaggcc
    57301 ttagagcatt aaatcaaaaa caattgcgtg atggtattta ctatttaaat gccagcatgt
    57361 taaaaactga cttagcatct gagtccatgt caaacaaggc tattaatcat cgagtgactt
    57421 tggtagttaa aaaaggtgtt tcctatttag aagttgagtt tagagggata aaggttggta
    57481 aaatgttagg ctaccttggt gaattgagct atttcgtaga tggttaccaa agagatttag
    57541 ctggtaaacc agttggtcga acaaaaaagg cagaggttgt gtcttatttc acggatgtaa
    57601 ctggcctacc attggcagat cgttatggaa aaaactatcc aaaagtgctg cgtatgaaat
    57661 tgattgaaca agcgaagaaa gacggacttg tgccattaca ggtctttgtg cctatcatgg
    57721 atgccatttc aaaagggtct ggccttcaaa ccgtttttat gcgtttagac tgggcaagcc
    57781 ttacgacaga gaaggcaaag gttgtcaaag aaactaataa tccacaagaa aatagccatc
    57841 taacttcaac agatcagttg aaaggacctc aaaatcgtca acaagaaaaa acacctacaa
    57901 gtcctccttc agcagctact ggtattgcta acttaactga tctcctggct aaaaaagcaa
    57961 ccggccaatc aactcaagaa acttctaaga cagatgatac tgataaggca gagaaattga
    58021 aacagttagt gcgtgaccat caaacatcaa ttgaaggtaa aacggcaaaa gatactaaga
    58081 ctaaaaaatc tgataagaaa catcgttcca atcaacaatc aaatggtgaa gaaagtagct
    58141 ctcgttatca cttaattgca ggtctatcta gctttatgat cgtagctctg ggattcatta
    58201 ttggtcgaaa gacattattt aaataagaaa cttagtacca agtgaaataa caaaaaagct
    58261 agtcagcaag agctaaaaac atacctattt ccgacaggac tcctgataca ggttgaagta
    58321 gtcgcaagat aggtgtgttt ttcacatttg gagatgttat aaaatgggaa tcatttaaaa
    58381 aatgaaataa gatgtttaag aaaagataga caagaggagc atatgacaaa ggtagtaata
    58441 aagcaattgt tgcaggtaat agtagtgttc atgataagtt tatcgacaat gacaggtgtt
    58501 gtgtatgcag ataaaggtca aatttatgga tgtattattc agagaaatta tcgtcatccg
    58561 atatctgggc agatagaaga tagcggaggt gagcattcct ttgatattgg tcaaggtatg
    58621 gttgaaggga ctgtctatag tgatgccatg ctagaagtat ctgatgctgg aaagatcgtt
    58681 cttacttttc gtatgagctt agctgattat tcgggcaatt atcagttctg gatacaacct
    58741 ggaggaactg gaagctttca ggcagttgat tacaatatca cccaaaaagg tactgatacc
    58801 aatgggacaa cactagatat tgctattagt ttgcctactg taaatagtat cattcgagga
    58861 agcatgtttg ttgaacctat gggcagagaa gtggtctttt acctgtcagc ttcagagtta
    58921 atacaaaagt attcaggtaa tatgttggcc cagcttgtta ctgaaacaga caattctcaa
    58981 aatcaagaag taaaagacaa tcaaaagcct gttgatacaa aactaggaga aagtcaagat
    59041 gagtctcaca caggtgctat gataactcag aataagccta aagccaactc atcaaataac
    59101 aagagtctat cagataaaaa aattcttcct tctaagatgg gcttaacgac ttctttagag
    59161 ttaaaaaaag aagataagtt tcggtctaaa aaagacttat caatcatgat ttactacttt
    59221 ccaacttttt ttctgatgtt aggagggttt gctgtatggg tttggaaaaa gaggaaaaaa
    59281 aatgataaaa cgatgtaaag gaattggtct agccttaatg gccttctttt tggtagcttg
    59341 tgtgaatcag caccataaaa cggctaaaga gtctgaacag cagagaattg tagccacttc
    59401 ggttgctgtg gttgacatct gtgaccgttt aaatttagac ctcgttgggg tttgtgatag
    59461 taaattatat acccttccta aacgctatga tgctgttaag cgtgtgggtt tacccatgaa
    59521 tcctgatata gagttgattg cttctttgaa accaacttgg attttgagtc ccaattcttt
    59581 acaagaagat ttggaaccca agtatcaaaa attggatact gagtatggtt ttttgaactt
    59641 acggagtgtt gagggcatgt accagtccat tgatgattta gggaaccttt tccaacgtca
    59701 acaagaagca aaagaattgc gccagcaata ccaggactat tatcgtgctt tccaagctaa
    59761 acgtaagggg aagaaaaagc ctaaagtgct tattcttatg ggcttgccag gtagttattt
    59821 ggtggcgacg aaccaatctt atgtagggaa tcttttggac ttggcaggtg gtgagaatgt
    59881 ttatcagtca gatgagaaag aatttctatc agctaatcct gaagacatgc tggctaagga
    59941 gcctgacttg attttacgaa cagctcatgc cattccagac aaggtaaaag tgatgtttga
    60001 caaagaattt gctgaaaatg atatttggaa acattttacg gcagtcaagg aagggaaagt
    60061 ctatgatttg gacaataccc tgtttggcat gagtgctaaa ttgaactacc cagaagcctt
    60121 ggacacctta acacagcttt ttgaccacgt gggagatcat tcgtaacatg acagcatcag
    60181 atttacaaag ggatcaatcc ctactggcta aaaaacgttt cagaagtggt ctttatctag
    60241 ttcttttaat tctcagtctc ctgtttttgg cggttattgc cttatccctt ggtggtttgg
    60301 cggtttctta tggggcaatt gtcaagggac tgtttgtggc ttatgacccc caagtggctt
    60361 tgatttatga tttgcgcttt ccaagaattg tcattgcttt attagcagga gcagggatag
    60421 cggtttcggg agttcttttt caagcagtgt tgaaaaatcc tatttcagac cctgctatta
    60481 tagggatttg tagtggtgct agttttatgg ttttagtctc tagtttactt ctaccgcagt
    60541 tgctgctgta tggtccaatc gtatcctttt taggaggcgg agtgtctttc ctgctgattt
    60601 atggtttagc atggaagaag gggcttaatc ctattcggct tattctaaca gggattgcta
    60661 ttaatgcttt atttatgggg ttatcaactg ctttaaccag ctttttcacc tcagctagtc
    60721 ccatggtcaa tgctctttta gcaggtcata ttagtcaaaa aacatgggct gatgtagggg
    60781 ttttattccc ttatacattc attggcttgt tactagcttt gttattgtca aaaacctgta
    60841 accttcttct tttagatgat caggtgattc gtcatttagg aatcgatgct acagcgttac
    60901 ggttgggaat ttccttggtt gctgttttat tggcttcggt agccacttcg atcgttggag
    60961 tggtttcttt cctaggcttg attgtccctc atatgagccg cttgctggtt ggaagtaagc
    61021 accaaatctt aattcctttt tcagctttgc ttggagcctt tgtctttttg ctagccgata
    61081 ctttaggaag aagtcttgct tacccattgg aaattagccc tgcgattata atgagtattg
    61141 taggcgggcc ttactttatt tacctgctaa ggaggtctga tattatatga gtaagaacag
    61201 cagtcatatt caggtgcaaa acctttcctt tgcttatgag gaaaaacttg ttttagatga
    61261 cctgaccttt agcattccaa aagggaaaat taccactatt atgggggcaa atggcagtgg
    61321 caagtcaacc ttattacaat tattaaccaa aaaccttccg ttaaaacaag ggcaggtttg
    61381 gcttgagcag gaagaattag caacgatttc tctcaaggct tttgcgaaaa aagtggcagt
    61441 ggtacaccaa taccatcaag tggtcgaagg tttgttagtg ggtgaattgg tagccatggc
    61501 taggcttgcc cgtcgttctt tttttaaaac tactaccaaa gaagatgagg aacgccttgc
    61561 ttgggcctta gaagtaacgg ctttgagtga ttatgtttat cgtgacctcc aacacctttc
    61621 tggtggtgaa cagcagaggg tttggattgc catggccctt gcccaggata cagatattat
    61681 ttttttagat gagccaacga cttatttgga tattaagtac cagcttgaca ttctcaagct
    61741 gattactaaa atcaaccaag agctaggcct aacgattgtg ttagtattac atgacatcaa
    61801 tcaggccttg tctctttcag accatcttat tggactgaaa gatgggcgac tttatgccca
    61861 agggcaacca agagacctcc ttgatcaaca gtttatcaga gatgtctttg gtgttgaatt
    61921 gccctttgtt gagagaaatg gtcaacagtt tgtcctcact tcattggtca atgaaaccaa
    61981 tgatattaga actcaaagga gagataggaa caagaacaga tgatggaaac agaagataca
    62041 atatcaaggg gaaaaaggaa aagactgtta aaacgattac gtgaacgaat tgcaccaaaa
    62101 aggtatttgc tttatgtgtc agccttttta tcttggttac aatttgtgat gaggatgatc
    62161 agtttttacc tcattgccaa aacgttttcg acctttattt tgggtcatgc tattgcctta
    62221 ggacgcttgg caggtttact cctactttta aatgtggtag gctttgttct tgctatatta
    62281 ggcaagcaac tgcaagggat cgcttcacaa tttgctagag attcactcaa acaatctttc
    62341 tttgaggctt ttattgattt agacgggcaa tttgatgctc atgccagtga tgctgatatt
    62401 ttaacgttgg cttcacaggg gattgatagt ttggatactt attatggtta ctatttgtct
    62461 ttgtctatga gaaccaagtg gaactgcaca actattatga tactagtttt tttaatttat
    62521 ccattggcag gccttgtctt tttaggagtt ctgcttctga ttccactttc aatcgttgct
    62581 atgcaaaagc ggtctaagca aattatgagt cattattggt cttcttatat ggatgttggt
    62641 aatttattta tggatgactt aaaaggtctt aatacactgt attcttatca agcaatagaa
    62701 cgttacgagc aagaattttc gggtaaggca gaacagtttc gaaaggctac catgtctttg
    62761 cttggctttc agttacaagc agttggttat atggatgcag ttatgtatct gggaattggt
    62821 ttgtcaggtt ttttagccgt tcaagctttg gcaacaggcc agttatcctt ttttaatttc
    62881 ctcttttttc tcttgattgc tacagaattt tttacaccga ttcgtgagca gggttatggc
    62941 atgcacttgg tcatgatgaa taccaaaatg gctgaccgta tctttagttt cttggatagt
    63001 gttccagcaa ggaaagataa caagagtaaa acagcaataa actttaacca gattgacatc
    63061 caaaatattt ctttagctta tgagaaaaaa acagtgctta gtggggttac catgacatta
    63121 acgaagggcc aactaacagc tatcgcgggg gtgtcaggac aaggaaaaac aagtctagct
    63181 caactcctct tgaaacgcca gtctgcaacg actgggcata ttttatttga cggtttagac
    63241 agtgacaatt tgttgcaaga aactatcaac cagcaggttc tttatgtatc ggaccaatct
    63301 accttattga accgtagcat ttacgataat ttaaggttag cagcaaatct ctctaaaaaa
    63361 gaaatcttag attggataga tcaacatggt ttgttaagct tcatcaactg gctaccagat
    63421 ggtcttgaca caatagttgg tgaaaatggt aacctgttat caccaggcca aaagcaacag
    63481 gtgatttgcg caagagctct attaagtaag aggtctcttt atatctttga tgaggcaaca
    63541 tctagtctag atgcagaaaa tgaacgtatt attgacaatt taataacgag attagctaag
    63601 acagcaatag ttattgtgat tactcataag atgtctcgac tgaaaggagc taaccaagta
    63661 ctctttttaa acacagggca gcctgcttgt ttaggcaaac cttgcgacct ttatcgggac
    63721 caaccaactt atcgtcacct agttgatact caagcaagac tggaggcaag tatttatggc
    63781 taaacctaac agatctacct taagcctggt ttggcgttta ttaaccctaa tgaaaactct
    63841 gctaccttgg attatcttgg ctgttggctt tgctgttatg ggttttgtca tcacggtaag
    63901 tattccaact ggaatagctt atttaggact actagctatt agacaagaag tgattccaat
    63961 attagcttta tatcttttga ttgctctagc ctttttaaga ggttttgttc gttatggaga
    64021 gcattatttt ggtcattttg ttgcttttca tagtttagca gcttttagga acttgatctt
    64081 taagaaacta agagctcttt ctccagcttg cttggatagt caagacagtg gttatttgct
    64141 taaaatgatt ggagaagata ttgaggcatt agaagttttt tttgcccaca caatcgcacc
    64201 tatttgtaca gcaatattgt ctgcaggttt aatgttctgg tacttttgtc aaagtagttg
    64261 gcagttagcc ttattagctt tggcaaccta tgcttgttta gccattgtta tacccattta
    64321 ttttgctaat attttacagg ttttactaaa aagccaaaat gaaggtcgaa aagattacct
    64381 gtcttatttt ttagagagtt tacgatcagt caaagatctt ttgcaatttc aggtattaga
    64441 cgagcaattt gaacgattaa taaaaaaaag taatcatgta aatgctcttg atcgtaacgt
    64501 agcgcaagcc caatttttgc aaatggcatt gacttttttt tggcttggct taatgatctt
    64561 agcattttct tatatggttt ttgatgggat atgccatgac agcttatcat ttgataaagg
    64621 cttattaact tttattgctt tcactgcttc gttttctcct tttttagaac taggacgttt
    64681 gtcattaggc tttaagcgtg ctatgaatgc ggctcgaaat atttttgacc ttctagacga
    64741 aaatgtcata gtagacgaag gcacaaaaca gatagatcgt ttaaggagtg tttcttttga
    64801 ggacctcagt tttgcttatc caaagcgcca agagctggtt tttaaggatt tatcagttac
    64861 ctttcaagaa aaggggatta ttggcattaa aggcgaatca ggatctggta aatcaacttt
    64921 ggtgaaatta attatgaaat ggtataattg gaagacagga gatatttttc ttaatgatag
    64981 gaatagttgc ttactaaatg ctgctaaatt acaagatact attgcttatg tgccacaaac
    65041 agcgcagctt ttccaacagt ctatccgtga aaatcttacc tttggccgtc aagatatttc
    65101 agatgagtcc atttggaatt tagctgagac ttgtggtatg aaagacagac tgttagcttg
    65161 taaggaaggt ttggatacga ttatcaagag tccttctgac ttttcagctg gagaaggtca
    65221 acgtttagag ttgatgcgag ctttattgaa agatgcgagt tgctatattt ttgatgaacc
    65281 cacgtcaaat ttagattctc taaatgaagc tatcttgctt gatttaatta aaacacattg
    65341 tcaaggattg gtcttcttaa tttctcacag gccatcaacc ctagcttgtg ctgatcatct
    65401 attttgcgta aaaaatggtt ccctaaaaga ggtgaataaa aaatgaaaca gttaacaata
    65461 aaagatatta tgataacagg cgcatttgcc gcgctctact ttatttgtgt tggtctaggc
    65521 acgtttatta acatcttttt tgatcgctca ggaaatatgt tatatgcccc tgcctttgca
    65581 gctttactgg ggggaacaat ttattttctt ttgattgcta aattgcaaac atttgggcca
    65641 ataacattat taggattgat gatgggaggt tttttcttcc ttagtggtca cttttttgcc
    65701 gcgatgtttc ccagcattat tttcggttta atagcggata ttattgcttc tttaggaaaa
    65761 tacaagtcaa ggttttttaa tgacctatct tatatggttt ttgcttttgt caatagtggc
    65821 cctattgtgc tgatgtggtt gttgaaagat gcctatgttg aaagtttgtt agcccgcggt
    65881 aaaagtatga cctatgtcaa tcgcattatg tatgatttta gtttagggca tgttatttgg
    65941 tttgtaggaa ttgttcttgc aggagcctta ttagggtcag cttttgcaca ttatttacta
    66001 aagaaacatt ttatcaaatc aggattgtta tcatgaggct tgatgttcgc accaaactgc
    66061 ttttgttggt acttgccaat gcctgcttct ttttccgtgt tgatggcttt ttagaattta
    66121 taattgttat ttttctctta ttacttttgt ctgctttaaa taagaaaaag ctagcattca
    66181 agttggcggt tgtttatctg ttaatgatcg gtctatctgt aatcccgcta tctattttcc
    66241 cttcttatct tgatcactta ttgagttttg tctcaatagc aggaaggtta gttttccctt
    66301 ctttactagc aggtttaatt actattaaga caactaccat ctacgaattg gttcatggat
    66361 tacgcaaatg gcatttccca gaagtctggc tattgacctt agccgttatg tgccgtttca
    66421 taccaatgat tagacaagaa tgttgtgtta ttcatcgctc tttaacaatc agggggatta
    66481 ttttaacaaa atggtctatt ttgatcagac ctaaacaata cttggagtat ttaatggttc
    66541 cattgctttt atctttgata agaagtagcc aagaactaac tatcgctagt ctaactaaag
    66601 ggctagcagt caacaaaggc accagtgaat gctttagctc acacttaaca tggaaagatt
    66661 ggggggtgca gatttggatt actgttatca taatcatcac gatactgcaa tgatttcagc
    66721 agaacaactt gtttttacct atcatgatca aaaaaatcca gcttgtcagg tatcgacttg
    66781 tcaaattgcc tctggacaat tcattgtttt gtgtggacct tctggttcag gtaaatctac
    66841 ctttttaaaa cttcttaatg gcataattcc tgattattat gctggaaaat atgaaggtag
    66901 actagatgtg gctgattgcc aagcagacag agacagtgtt gaaacatttt ctagatctgt
    66961 ggcctctgtt tttcaaaatc cagccagtca gtttttctat cgcgaagtcc aacacgaact
    67021 ggtctttccc tgtgaaaatc aaggtttaga tgcaaaggtt atcatgaagc gtctttggac
    67081 tttagcagaa gattttgctt ttgcagagct ccttaacaag gatatgtttg gattgtcagg
    67141 agggcaaaaa caaagagttg ctattgcaac ggccattatg caaggtacta atattatgct
    67201 ttttgatgag ccaactgcta acttagatag tgcaggcata gctgctgtta aagcctatct
    67261 tacccaatta aaagcagcag gaaaaaccat tattgtagcc gagcatcgct tacattactt
    67321 gatggatttg gcagataact ttttctactt taaaaatggt agattaacag ataagttaac
    67381 aacacaagat ttgctagcct tgacagatga acaacggcaa gatatgggac tacgtcgctt
    67441 agacttgtct gacctaaaac ctgtgttagc tggtaagatt gagagtcaac attatcgccc
    67501 agatgatagc ctgtgtattg agcatctaac agttagagcg ggaagcaaaa tacttagatg
    67561 tattgaacag cttagttttg ctgcaggaag tatttctggc attacaggat caaacgggct
    67621 tggaaaatcg caattagttt attatatagc tggtatctta gacgataaaa aagcaactat
    67681 taagtttcaa ggcatacctt tatctgccaa gcaacgttta tcaaagacta gtattgtctt
    67741 acaagaagtt tctttgcaac tatttgcaga atcggtttca aaggaagtca acttgggcca
    67801 tgaacgacat ccacggacga cagaagtaat agagcggtta tctttaacga ctcttttaga
    67861 acgtcatcca gctagtttgt caggaggtga gcaacaaaga gtgatgattg ccgctagtct
    67921 tttggctgat aaagatatct taatttttga tgagccaagt agcggacttg atttgttaca
    67981 aatgaaggct ttagctaatc ttctcatgca gctgaagacc caacataagg ttgtcatcct
    68041 catttcacat gatgaagaac ttctaagtag tgtctgcgat accatttatc aaatgctacc
    68101 ttaacgagcc cctagaactg tttaaaagta ctaaaaggct tttatctgaa aataaatagg
    68161 aactcttgta taatagatac aagagtcaga acgtagacaa ctccagtttt atgctcaaaa
    68221 agcatgcata gctctgctga tttgacattc ggtttccgat ttttacatat aaagtgagcc
    68281 aaaacagatg ctttttgctg tggtaaaaga gtggcgtcaa tacgagattg acgccactcg
    68341 ggatttttga gacctcaggc tcaaaaataa aggcatggaa ttccaaagaa cgtcgctgcc
    68401 gtaagcacca cctaaggaaa gtatcacgac aaactttgtc ttcaatctga caagagtttt
    68461 tgtgaaggga aaaagataat gatattaaca gctcctatgt ccaacttaaa gggatttgga
    68521 ccaaaatcag cagaaaaatt tcagaaatta gatatttata cagtagaaga tttactgctt
    68581 tattatccgt ttcgctatga agattttaaa tcaaaatctg tttttgattt agtggatggt
    68641 gaaaaagcag tcattacagg cttagtcgtt actccagcta atgtacaata ttatggtttt
    68701 aaacgtaacc gtttaagttt caaattgcgt caaggggaag ctgtcttaaa tgttagtttt
    68761 tttaatcaac cctatttagc tgataaaata gaacttggtc aagaggtagc tgtttttggt
    68821 aaatgggatg ccactaaatc ggctattact gggatgaagg ttttagctca agttgaagat
    68881 gacatgcaac ctgtttatcg cgtagctcag ggaatttcac agtctacttt gattaaagct
    68941 attaagtcag cttttgaaat cgatgcgcat ttggaattga aggaaaattt accagctact
    69001 ttattggaaa aataccgatt gatgggtcgt agtcaggctt gtttagctat gcatttccca
    69061 aaagatatca cagagtataa gcaagcgctc cgtcggatta aatttgaaga attattttac
    69121 tttcaaatga accttcaagt tttgaaagcc gaaaatagat ctgaaacaaa tggtttgcct
    69181 attctttata gtaaacatgc tatggagaca aagatttcct ctttaccctt tattctaaca
    69241 aatgctcaaa agcgctcttt agatgacata ttatctgata tgtcatcggg agctcatatg
    69301 aatcgtttat tgcaaggaga tgtaggatca ggaaagacag tcattgctgg tctatcaatg
    69361 tatgcagctt atacagcagg ttttcaatcg gctttgatgg ttccaacgga aatcctagct
    69421 gaacaacact acattagtct gcaagagtta tttccagatt tatcaatcgc tatattaact
    69481 tcgggtatga aagcagctgt caagcgtacg gttttagcag ctattgcaaa tggctcggtt
    69541 gatatgattg taggaactca tgctcttatc caagactcgg tacagtacca taaactgggg
    69601 cttgtcatta cagacgagca acatcgtttt ggtgttaaac agcgtagaat tttccgtgaa
    69661 aagggagaaa atcctgatgt tttaatgatg acagccaccc caattccccg aactctagca
    69721 atcacagctt ttggagaaat ggatgtttct attattgatg aattacctgc cggtcgtaaa
    69781 cctattatga cacgctgggt gaaacacgag cagctaggta ctgtgttgga atgggtaaaa
    69841 ggtgaattgc aaaaagatgc tcaagtgtat gtcatttcac cgttgattga agaatcagaa
    69901 gctttagatt taaagaatgc agtagcattg catgctgaat tatctactta ttttgaagga
    69961 attgctaagg ttgctcttgt acatggacgt atgaaaaatg atgaaaaaga tgctataatg
    70021 caagatttca aggataaaaa aagtcatatt ttagtatcca caacagttat tgaagtaggg
    70081 gtaaatgtcc caaatgcaac gatcatgatt attatggatg ccgatcgttt tggattaagt
    70141 cagttacatc aacttcgtgg gcgtgttggt cgtggatata aacaatcata cgctgtttta
    70201 gtggctaatc ccaaaactga ttcggggaaa aaacgaatga caatcatgac agaaacgaca
    70261 gatggtttcg ttttagctga gtcggattta aaaatgcgtg gttctggtga aatctttggt
    70321 actcgtcagt ctggaattcc agaatttcaa gtagctgata tcgttgagga ttatcctatt
    70381 ttagaagaag cacgcaaagt ttctgcagcg attgtttctg atcctaactg gatatatgaa
    70441 aaacagtggc aattagtggc acaaaatatt agaaaaaaag aagtttatga ttaacttaaa
    70501 acaagtcgtt gttttacaaa tatttagtta gttttgagat aaactgttat aaagtataaa
    70561 gaggtcacta tttctggcct tttttactta tgctttacga tgagactgct atgtgaagca
    70621 gtattaaccc attttcagta taactttttt attgctaaaa taatcatatt attaaaattc
    70681 tta
//
LOCUS       DATWEK010000007        63693 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.007, whole genome shotgun sequence.
ACCESSION   DATWEK010000007 DATWEK010000000
VERSION     DATWEK010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63693
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.007"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(105..404)
                     /locus_tag="VCR92_000547"
     CDS             complement(105..404)
                     /locus_tag="VCR92_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267637.1"
                     /translation="MFLTWENLFLTNQSRRRLKLLVVERSYNNVGNFLKEYFGGFFEI
                     INFDDLRLTMVDMVSLSSEYDVIVTDMILEQTMDSEILFFNQMAPSVVANRLTDM"
     gene            complement(561..1028)
                     /gene="perR"
                     /locus_tag="VCR92_000548"
     CDS             complement(561..1028)
                     /gene="perR"
                     /locus_tag="VCR92_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEP4267638.1"
                     /translation="MDIHSHQQALDAYENVLEHLREKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPNFPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEICGKIADFMDVDVMDIAKEAHEQTGYKVTRIPVIAYGICPDCQAKDQSDF"
     gene            complement(1080..1535)
                     /locus_tag="VCR92_000549"
     CDS             complement(1080..1535)
                     /locus_tag="VCR92_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEP4267639.1"
                     /translation="MIYSFQNPSEDILKAYLESAKTIAVVGLSDRKDTAAYGVAKFMQ
                     AMDYRIIPVNPKLAGQLILGEKVYASIKAIPFEVDIVDVFRRSEFLPEVARDFLAGQA
                     KVFWAQLGLENQEVQTILRSAGKEAIVMNRCLKIDYLQLVAKPECITNL"
     gene            complement(1722..4364)
                     /gene="polA"
                     /locus_tag="VCR92_000550"
     CDS             complement(1722..4364)
                     /gene="polA"
                     /locus_tag="VCR92_000550"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEP4267640.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLT
                     ALGIAYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKK
                     GVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGS
                     LEGIYEHIDGFKASKMKENLINDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVAS
                     LSQFYDEMDFVQLKKGLASQMPQEPVAAISYQEVTNVSADLFSAEDIFYFETLRDNYH
                     CEAIIGFAWGHGEQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVA
                     PSYDARLANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLA
                     RKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQ
                     NKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGA
                     DIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQAKSYI
                     DTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTM
                     EAAVDLAVPLCVDESTGQSWYEAK"
     gene            complement(4495..6222)
                     /locus_tag="VCR92_000551"
     CDS             complement(4495..6222)
                     /locus_tag="VCR92_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEP4267641.1"
                     /translation="METILQTKLPVAQLVEQLTEWLTKTFSGLFDIMQVVGSFLMDWM
                     TKTLLFIHPLLFIVLVTAGVFFLAKKKWPLPTFTLLGLLFIYNQGLWKQLMNTFTLVL
                     VASLISVLIGIPLGIWMAKNATVRQIVNPILDFMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLAIRDIPTELIEASDAFGSTGKQKLFKVELPLAKNTIMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADVGSGFVSGLALVILAIVLDRMTQLF
                     NSKPQEKAKAGKTNKWIGLAALAVFLIAALGRGIMAMTSGMADKGETVNIAYVQWDSE
                     VASTHVIAEVLKNEGYHVTLTPLDNAVMWQTVANGNADFSTSAWLPVTHGQQYQKYKS
                     KLDDLGPNLKGTKLGLAVPKYMTDVNSIEDLSKQADQKITGIEPGAGIMAAAQKTLKE
                     YHNLSSWELVAASTGAMTTSLDQAIKKKDPIVVTAWSPHWMFAKYDLKYLKDPKETFG
                     STENINTIARKGLKKDLPNVYKIIDKFHWTQKDMEAVMLDINKGMSPEAAAKKWVEAN
                     QSKVSSWTK"
     gene            complement(6238..7434)
                     /locus_tag="VCR92_000552"
     CDS             complement(6238..7434)
                     /locus_tag="VCR92_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEP4267642.1"
                     /translation="METILEVKHLSKIFGKKQKAALEMVKTGKNKSEIFKKTGATVGV
                     YDASFEVKKGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGKDISTMSADQLRE
                     VRRHDINMVFQSFALFPHKTILENTEFGLELRGVPKEERQRLAEKALDNSGLLDFKDQ
                     YPNQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRREMQDELLDLQDSMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEEILTNPANDFVREFVEDVDRSKVLTA
                     QNIMIKPLTTTVELDGPQVALNRMHNEEVSMLMATNRRRQLVGSLTADAAIEARKKGL
                     PLSEVIDRDVRTVSKDTIITDILPLIYDSSAPIAVTDDNNRLLGVIIRGRVIEALANI
                     SDEDLN"
     gene            complement(7921..9012)
                     /gene="ulaG"
                     /locus_tag="VCR92_000553"
     CDS             complement(7921..9012)
                     /gene="ulaG"
                     /locus_tag="VCR92_000553"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEP4267643.1"
                     /translation="MTKVQDITRESWILNTFPEWGTWLNEEIEQEVVPADNFAMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKQVKDMVRGHQMANMAGARKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLNHVKFVGPYECGEVWKNWGVPKD
                     RIMILKPGDSFEFKDIKITAVESFDRTCLVTLPIQGADAQDGDLAGLAITDDDMARKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYDFHPFIWEVGGKYTYPQ
                     DQNRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(9265..10911)
                     /locus_tag="VCR92_000554"
     CDS             complement(9265..10911)
                     /locus_tag="VCR92_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEP4267644.1"
                     /translation="MMILDKKSYDLLSYLLKLETPETVMAISHALNQSRRKVYYQLDK
                     INKALPKGVDQIISYPRLGILLTADQKAACRLLLEEVTDYNYVMKSDERRRLSSIYIA
                     VSTERVTIDKLMQINDVSRNTILNDLTELREELEDKQYKIQLHATKARGYYFGCHPMA
                     LIQYLYKLLVDVYQGGNTSFIDIFNRKLSEIQGLSVYFSKDILTYFHEYLFLSQASLG
                     KTINTQDSQFMLQILPFMLLSYRNMRLDSETKSALKQEFHLIWKRKEYHIAQDLAREL
                     YHNFKLHLDDIEVSMVAMLMLSFRKDQDHHVESQDYDDMRATISHFIDQLESRYQLHF
                     THKQDLLKQLTTHCKALVYRKAYGIFLVNPLTDHIKEKYEELFAMTQSCATILEQDWT
                     ISLTDDDIAYLTIHLGGELRHNNTEQEKTKLVIVSDDGIGIQKLLFKQCQRYLANGQI
                     EAVFTTEQYQSVYDLLAVDMIVATTDTLKTKIPMLIVNPILSDDDIIKLIRFSKQGRL
                     SEHSRFSTELTKAIEAVVKDESDRYALVSKIEKLIHRELL"
     gene            complement(11236..11940)
                     /locus_tag="VCR92_000555"
     CDS             complement(11236..11940)
                     /locus_tag="VCR92_000555"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEP4267645.1"
                     /translation="MAKNLQEMRERVCAANKSLPQHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDLLTPENMVVTDLDGNVVEGDLNPSSDLPTHVELYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPVPCARSLTKAEVDGAYEQETGNVILEEFSKRGL
                     DPMAVPGIVVRNHGPFTWGKTPEQAVYHSVVLEEVAKMNRLTEQINPRVEPAPRYIMD
                     KHYLRKHGPNAYYGQK"
     gene            complement(11942..12805)
                     /locus_tag="VCR92_000556"
     CDS             complement(11942..12805)
                     /locus_tag="VCR92_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEP4267646.1"
                     /translation="MARPIGIYEKATPKQFTWRERLQFAKDLGFDFVEMSVDESDARL
                     ARLEWTKEERLDLVKAIYETGIRIPTICFSGHRRYPLGSNDPATEAKSLKLMKQCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQSCDWAEEAQVMLSIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDAGNVSAWHNDLWSEFYNGHKSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWQELFAVLKKTNYNGPFLIEMWSENCDTVEETKAAIKEAQDF
                     LYPLIEKAGLA"
     gene            complement(12810..13472)
                     /locus_tag="VCR92_000557"
     CDS             complement(12810..13472)
                     /locus_tag="VCR92_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEP4267647.1"
                     /translation="MTHIPNLQVALDHSDLQGAVKAAVAVGHEVDVIEAGTVCLLQVG
                     SELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMEAALKA
                     IKEERGDRGEIQIELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNKV
                     KKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIKRI
                     WG"
     gene            complement(13579..14064)
                     /locus_tag="VCR92_000558"
     CDS             complement(13579..14064)
                     /locus_tag="VCR92_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEP4267648.1"
                     /translation="MNLKQAFIDNNSIRLGLSADTWQEAVQLAVQPLIDSKAVTSAYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGLGVNRNAFALITLTKPVTFSDGKEVSVLLT
                     LAATDPSIHTTVAIPQIVALFELDNAIERLVACQSPKEVLEMVEESKNSPYLEGLDLD
                     A"
     gene            complement(14187..14465)
                     /locus_tag="VCR92_000559"
     CDS             complement(14187..14465)
                     /locus_tag="VCR92_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEP4267649.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQEVL"
     gene            complement(14536..15969)
                     /locus_tag="VCR92_000560"
     CDS             complement(14536..15969)
                     /locus_tag="VCR92_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEP4267650.1"
                     /translation="MEMLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPIYEVFAG
                     FVKATVGYLILNVGAGGLVTTFRPILVALAKKFELKAAVIDPYFGLAAANTKLEEMGF
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQFQNA
                     FGAWAVGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPIFGKKE
                     ENLDNLKLPTFLNIFHDTVVASATLMLVFFGAILAVLGPDIMSNVELIGPGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFAFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVLV
                     CIFLLAIPQLQFAKAKDKEAYYRGEAQ"
     gene            complement(16276..18777)
                     /locus_tag="VCR92_000561"
     CDS             complement(16276..18777)
                     /locus_tag="VCR92_000561"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEP4267651.1"
                     /translation="MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTADQ
                     AEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGNEMPVWIADYVLASYGT
                     GAIMAVPAHDERDWEFAKQFNLDIISVLEGGNVEEAAFTEDGLHINSGFLDGLDKASA
                     IAKMVEWLEAEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD
                     KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHL
                     GEELWQALTASGESISYVPWPSYDKSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     QEVALANEKVQAEITGKDIIKVIAVPNKLVNIVIK"
     gene            complement(18988..20127)
                     /locus_tag="VCR92_000562"
     CDS             complement(18988..20127)
                     /locus_tag="VCR92_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEP4267652.1"
                     /translation="MRENTTLLHGYTVIDEFTGAASVPIYQTSTFHNSELYCPSQKHL
                     YTRFSNPTTEALEDGLACLEKATYAVAYASGMAAISTVLMLLKAGDHVIFPLEVYGGT
                     CQFATAILPNYQIETSFVDMADLATVKASIRPNTRMIYLETPSNPLLKICDISELVQL
                     AKAYGVLTVADNTFMTSLYQEPLAMGVDIVVESVTKFINGHSDVVAGLAATNNEAIYN
                     QLKLFQKNFGAIVGVEDAWLILRGMKTMGIRMEQAVKNAQQLANYLAKHPKVLKVHYP
                     GLDSHPNHDTHLQQAKNGGAVLSFELASKEELMIFTHRIQLPILAVSLGGVESILSHP
                     ATMSHACLSSQARLEQGVVDGLLRLSCGVENIEDLLADFEQALAF"
     gene            20611..20889
                     /locus_tag="VCR92_000563"
     CDS             20611..20889
                     /locus_tag="VCR92_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267653.1"
                     /translation="MKNKLFLVALATVTVLGPSLATPHHRTVHATEQTVTQRTATETC
                     TLNGKICYGYENPDEDYTDSMVQSKSQDQGFFSWLWTQITTWFSSLMS"
     gene            21032..21262
                     /locus_tag="VCR92_000564"
     CDS             21032..21262
                     /locus_tag="VCR92_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267654.1"
                     /translation="MKKKLSLFMIATAAVVGLSLATPENQTVSANAQTPAVQNCENGC
                     CDRPFFGYCGPFSWLYYNTRYFLGYSDTATNQ"
     gene            complement(21546..21923)
                     /locus_tag="VCR92_000565"
     CDS             complement(21546..21923)
                     /locus_tag="VCR92_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267655.1"
                     /translation="MKQQSYKPLHFVYLLMALLTAMLLIARPVMADEEDKDPWRLGYN
                     QDLTKGKEDGKVAEWTDLTPPDPEVPKSPKDIDDSNHEHYRDGYKDGYKEGYNEGFGG
                     SYPLLLPVKFIWGLILHWWEKLI"
     gene            complement(22174..23889)
                     /gene="slo"
                     /locus_tag="VCR92_000566"
     CDS             complement(22174..23889)
                     /gene="slo"
                     /locus_tag="VCR92_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_095889392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin streptolysin O"
                     /protein_id="HEP4267656.1"
                     /translation="MSNKKIFKKYSRVAGLLTAALIVGNLVTANADSNKQNTANTETT
                     TTNEQPKPESSELTTEKAGQKMDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDNKKSE
                     EDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTP
                     VDISIIDSVTDRTYPAALQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVN
                     DPTYANVSTAIDNLVNQWHDNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDG
                     TLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFDKSVTFKELQRKGVSNEA
                     PPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAV
                     VLGGDAAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRS
                     EYVETTSTEYTSGKINLSHQGAYVAQYEILWDEINYDDKGKEVITKRRWDNNWYSKTS
                     PFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNISGSTLSPYG
                     SITYK"
     gene            complement(23913..24398)
                     /locus_tag="VCR92_000567"
     CDS             complement(23913..24398)
                     /locus_tag="VCR92_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD glycohydrolase inhibitor"
                     /protein_id="HEP4267657.1"
                     /translation="MYKVPKGLEHYQKMFQKEVTVNDLKKYLIGSDKEYRITKRDSYM
                     GDISDPEVILEYGIYPAFIKGYTQLKANIEEALLKMSNSGQALDIYQAVQTLNAENML
                     LNYYESLPFYLNRQSILANITKALKDAHIREAMAHYKLGEFAHYQDTMLDMVERTIET
                     F"
     gene            complement(24403..25746)
                     /gene="nga"
                     /locus_tag="VCR92_000568"
     CDS             complement(24403..25746)
                     /gene="nga"
                     /locus_tag="VCR92_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotine adenine dinucleotide glycohydrolase"
                     /protein_id="HEP4267658.1"
                     /translation="MRNKKVTLAHIVAKTSVAIALAGAMGSSLLANNTTYAVSGKEGK
                     KSDVKYEMTKVMEANATSSKEDKHVMHTLDGSMSTVWEENSPGGGIGEVLSYKFASPM
                     HIGRILIVNGDTSSKENYYKKNRIAKADVKYYNGNKLVLFQKIELGDTYTKKPHHIEI
                     DKKLDVDRIDIEVTEVHQGQNKDILALSEVTFGNMERDIFEKKFKEIKDKWVTDKQAD
                     EFIETADKYADKAVQMSAVASRAEYYRMYVSRKYHYKKEFVEKLKQVYKESGASHVTS
                     KKDLMLAFDDAKRKSTIGRQENGLFVTSFAEDMALLFTDQGKLKSADQIENIKGVDSG
                     KYSDGVYQYEYDSELTKNIDKLGYIRTASGDTPGANSLNIPGCQTWSGKHIENSESEL
                     IFPSISVKDLKSKAVLAEIDAKGYFEIIDPTIIAPNGDHKKVTGRFKIKKMQDRK"
     gene            complement(26114..26653)
                     /gene="nusG"
                     /locus_tag="VCR92_000569"
     CDS             complement(26114..26653)
                     /gene="nusG"
                     /locus_tag="VCR92_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEP4267659.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTIDVFDTNIKEGDVVQIIDGAFMGQEGRVVEIENNKVKLML
                     NMFGSETVAEVELYQIAEL"
     gene            complement(26826..27869)
                     /locus_tag="VCR92_000570"
     CDS             complement(26826..27869)
                     /locus_tag="VCR92_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEP4267660.1"
                     /translation="MNKKVMSLGLVSTALFTLGGCTNNSAKQTTDNSLKIAMITNQTG
                     IDDKSFNQSAWEGLQAWGKENKLEKGKGYDYFQSANESEFTTNLESAVTNGYNLVFGI
                     GFPLHDAVEKVAANNPDNHFAIVDDVIKGQKNVASITFSDHEAAYLAGVAAAKTTKTK
                     QVGFVGGMEGDVVKRFEKGFEAGVKSVDDTIKVRVAYAGSFADAAKGKTIAAAQYAEG
                     ADVIYHAAGGTGAGVFSEAKSINEKRKEEDKVWVIGVDRDQSEDGKYTTKDGKSANFV
                     LTSSIKEVGKALVKVAVKTSEGQFPGGQITTFGLKEGGVSLTTDALTQDTKKAIEAAK
                     KAIIEGTITVPEN"
     gene            complement(28196..29488)
                     /locus_tag="VCR92_000571"
     CDS             complement(28196..29488)
                     /locus_tag="VCR92_000571"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEP4267661.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLVKELAYLHDEGVTTDNLRISDRA
                     HVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERL
                     RINLAEKNRLFEKMYDSTPLDFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGERIDHYPASLEQLKRCKPIYEELPGWQEDITGVRSLDELPEN
                     ARNYVRRVGELVGVRISTFSVGPGREQTNILESVWASI"
     gene            29926..30804
                     /locus_tag="VCR92_000572"
     CDS             29926..30804
                     /locus_tag="VCR92_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267662.1"
                     /translation="MIRKYDRTSTKKKSLNWIWLIIAFFMISSFIGGSSFTESLLDIL
                     PAIAIGGTGYAIFRVRSHQKRLAKAKVAKQLEDLKAKIQLADRKVRLLDTYLADHDDF
                     QYNVLAQQLLPQLSDIKAKAITLKDQLDPKIYRRITKKANDVESDITLQLETLQIATT
                     LNPQPLKTPSPNLINKAPELKPYYDNIQTDHQAILAKIQGADNQEELLALHEANMRRF
                     EDILTGYLKIKEEPKNYYNAAARLEQAKQAIQQFDENLDETLRRLNESDLKDFDISLR
                     IMQGATQRRTTHHQKD"
     gene            30817..32079
                     /locus_tag="VCR92_000573"
     CDS             30817..32079
                     /locus_tag="VCR92_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEP4267663.1"
                     /translation="MADFNFDIDQIADNAVVKTDKTTDIISDLPTDTNGQISFFEKLS
                     ADQQTAITARAPALVDTFLADQNALLDFGQSAVEGVNATVNHILAEQKKLQIPQVDDL
                     LKSTNRELNGFIAKYKDATPVDLDKKPNFLQKLFKQSRDTLQEFYFDSQNIEQKMDSM
                     AAAVVKQEDTLARNIVSAELLIEDNTKSIEHLVGVIAFIEASQKEASQRAAALQKDLK
                     TKDSATPDYQIKADLLARTTEVINTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGMMQQSVKSGMTADAIINANNAALQMLAETSKEAIPA
                     LEQSAQNPTLSMKSVTSLAESLVAQNNGIIAAIDHGRKERAQLESAIIRSAETINDSV
                     KLRDQNIVQALLSEGKETQKTIDKTTRA"
     gene            complement(32199..32825)
                     /locus_tag="VCR92_000574"
     CDS             complement(32199..32825)
                     /locus_tag="VCR92_000574"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEP4267664.1"
                     /translation="MARLNVKPTRMELSNLKNRLKTATRGHKLLKDKRDELMRRFVDL
                     IRENNELRQTIEKELAANMKEFVLAKASENSLMVEELFAVPVHEVTLWIDIENIMSVN
                     VPKFHVQSNTAREQEQGEFAYSYLSSNSEMDNTIQKTKELLEKLLRLAEVEKTCQLMA
                     DDIEKTRRRVNGLEYSIIPQLKETIHYIELKLEEAERASLVRIMKITS"
     gene            complement(32870..34285)
                     /locus_tag="VCR92_000575"
     CDS             complement(32870..34285)
                     /locus_tag="VCR92_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEP4267665.1"
                     /translation="MSVLKEYRTVSEVVGPLMIVDQVAGVHYNELVDITLHNGERRKG
                     QVLEVQGDKAMVQLFEGSTGINLAKTKVRFTGHPLELAVSEDMVGRIFDGMGQPIDGG
                     PELIPEKYLDIDGQAINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDDNFAVVFAAMGITFEEAEFFMNDLRETGAIDRSVLFINLAND
                     PAIERIATPRIALTTAEYLAYEKGMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLIGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSQE
                     LYKNGFRPPINVLPSLSRLKDKGSGEGKTRQDHAATMNQLFAAYAQGKQAKELAVVLG
                     ESALSETDKLYVAFTNRFEEEYINQGFYTNRSIEESLDLGWELLSILPRTELKRIKDD
                     MLDRYLPKADTTMTKVFVAND"
     gene            complement(34286..36061)
                     /locus_tag="VCR92_000576"
     CDS             complement(34286..36061)
                     /locus_tag="VCR92_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEP4267666.1"
                     /translation="MNQGKIITVSGPLVVASGMQEANIQDICRVGHLGLVGEIIEMRR
                     DQASIQVYEETSGIGPGEPVVTTGCPLSVELGPGLISEMFDGIQRPLDRFQKATDSDF
                     LIRGVAIPSLDRKAKWAFIPKLSVGQEVVAGDILGTVQETAVIEHRIMVPYKVSGTLV
                     AIHAGDFTVTDTVYEIKQEDGSIYQGSLMQTWPVRQSRPVAQKFIPVEPLVTGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQIAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLQEMPGDEGYPAYLGSRIAEYYERAGRVRTLGSQEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYQDDVGSYIDRKQ
                     QSNWSNKVTRAMAILQREASLEEIVRLVGLDSLSEQDRLTMAVARQIREDYLQQNAFD
                     SVDTFTSFPKQEAMLTNILTFNEEASKALSLGAYFNEIMEGTAQVRDRIARSKFIPEE
                     NLEQIKGLTQKVTKEIHHVLAKGGI"
     gene            complement(36262..36582)
                     /locus_tag="VCR92_000577"
     CDS             complement(36262..36582)
                     /locus_tag="VCR92_000577"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEP4267667.1"
                     /translation="MTKTLYKVGVIGNRDVILPFQMIGFQTFPVIKPQDAINQLRQLA
                     MEDFGIIYITEDIAAAIPEALTHYDNQVLPAVIPLPTHQGAQGIGLSRIQAMVEKAVG
                     QNIL"
     gene            complement(36579..37577)
                     /locus_tag="VCR92_000578"
     CDS             complement(36579..37577)
                     /locus_tag="VCR92_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEP4267668.1"
                     /translation="MPTFLELNTTISVKEKELLTKEQFDKLLQAPNTTTLARLLHQSV
                     YHLTVDDLNDLDRLESILMAELTKTYRWAFAETPQPDIVQLFTLRYTYHNVKVLLKAK
                     ASQADLSHLLLPIGDKPLVALEHLIRTMTSDEFPKEVVTEIQSIWAEYQDYQDIRVLE
                     IGTDLAYFKALKQIAQRLEDPVFQQAVLIVIDLYNLITVRRAKSQNKPISFMMQLLSD
                     EASRPSKTFITLEDDKDLMTWFENVTPDSYMTALKPYSEKLRQGTLQTTELEYLVDEC
                     LYHLFAKAKYQVDGPYVLARFLLAKSFEVKNLRLLAAALANDLPKERVIERMRPIA"
     gene            complement(37593..38177)
                     /locus_tag="VCR92_000579"
     CDS             complement(37593..38177)
                     /locus_tag="VCR92_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HEP4267669.1"
                     /translation="MNDITQLRQNVLEKAHQEGQQCLKIATDSLDTDFKERQQQGLHD
                     LKAKRQKELKAFEQQFQVAQQQLKNQERQALLALKQDSIKELFEASLEKMTNFSKEEE
                     LAFLKQVLSKYPEQPLQVTFGEKTGQKFSSYDCAELRLAFPQLSYNQELIPQEAGFLV
                     SLDQVDDNYLYRYLLESVLKEESSRIIDMLFSEI"
     gene            complement(38246..38725)
                     /locus_tag="VCR92_000580"
     CDS             complement(38246..38725)
                     /locus_tag="VCR92_000580"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEP4267670.1"
                     /translation="MEHLAHYFTAHGGVFFAALGIVLAVALSGMGSAYGVGKGGQAAA
                     ALLKEEPEKFTSALILQLLPGSQGIYGFAIGILIWMKLTPELSVNQGLAYFLVSLPIA
                     IVGYFSAKHQGNVSVAGMQILAKRPKDFMKGVILAAMVETYAILAFVVSFILLNKIG"
     gene            complement(38727..40727)
                     /locus_tag="VCR92_000581"
     CDS             complement(38727..40727)
                     /locus_tag="VCR92_000581"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEP4267671.1"
                     /translation="MAISQMKKLAMVFEKDYLDLVLKTLQQSQLVEVRDMKQLKHWQD
                     AFNKGNVKLPQIVQYDLTHQKPLLDDEALQYLLQSQQELENGLASLSAFLPPIGKLTA
                     LRQKTPSLSFKQFEERHRQQAAQTALKMMSQKIERLEQLQNKIDQLTEYCQELEKWRS
                     LTVLPQDLAQFHFLSARVGTIPSTANDHFYHQLKKHKGLFIEEVYHTEFEYGLVLFWQ
                     AQDTIHLQKYQFKPLLYKEQLLPSEQLRINKELLTNWLAEKDSLLKELRQSQKILAQL
                     QVEIDYVLSQYQRQQTKKQLLGTRHLIALEGWIEADSVNQLKGLMTKTLGDMFYLDSY
                     DVTPDDWEDVPIKLRNHRYIAPFELVTEMYALPKYQEKDPTPFLAPLYLTFFGMMVAD
                     LGYGLLLYAVTLAALVFFNLQKTSKRLVTFFNILAISVALWGLIYGSFFGFDLPVALL
                     STKTDVITILVVSLLFGFVTLIFGLLLGAWQQVRMKAYATAYTSSLAWTFILLGLLLF
                     ILGKNVSGLAYLSVIGKWLALGNAFGILVVSLLKSKSLLGLGSGLYNLYGISSYLSDL
                     VSFTRLMALGLSGASIGAAFNMIVGIFPPVTRFTVGIFIFILLHAINIFLSMLSGYVH
                     GARLIFVEFFGKFYEGGGKAFNPLKLADNYVNVNEETDLEDN"
     gene            complement(40717..41037)
                     /locus_tag="VCR92_000582"
     CDS             complement(40717..41037)
                     /locus_tag="VCR92_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267672.1"
                     /translation="MNTLLSLMNSIEQEARTIYDSYDAKKKALADKKEEELKQLFLEY
                     EQETQLLLEAKREVFFEANRQEQKASKKRLATQQLALHAILEEHKLTVVRELVDKVVE
                     TYGH"
     gene            complement(41491..42510)
                     /locus_tag="VCR92_000583"
     CDS             complement(41491..42510)
                     /locus_tag="VCR92_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEP4267673.1"
                     /translation="MDIIIGTSLLILVLAIFSLFNYKAPHGAKAMGALASAACASFLV
                     EAFQDSFFGKVLGFQFLSEVGGANGSLSGVAAAILVAIAIGVSPGYAVLIGLSVSGTG
                     IIPGFVAGYVVSFLIKWMEKNIPGGLDLISIIIVGAPLTRFLAQLITPVINSTLLTIG
                     DILTSSANSNPIIMGMILGGTIVVVATAPLSSMALTAMLGLTGIPMAIGALSVFGSSF
                     MNGVLFYRLKLGERKDNIAFAIEPLTQADVTSANPIPIYVTNFVGGAACGVLIALMKL
                     VNDTPGTATPIAGFAVMFAYNPVAKVLITALGCIIISLIVGYIGGSVFKNYRLVTKQE
                     LQARN"
     gene            complement(42547..42912)
                     /locus_tag="VCR92_000584"
     CDS             complement(42547..42912)
                     /locus_tag="VCR92_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEP4267674.1"
                     /translation="MKSYPEPMGPYSTYTIEGHFLYTAGQLPLNPVTGQLSDGFEAQC
                     RQVFVNLQSILAEQKLDLNHIYKLNVYLTDVTNVEILNHVMTDLFEEPYPVRTAVQVS
                     ALPLQALIEVEAVARVKQL"
     gene            43086..43766
                     /locus_tag="VCR92_000585"
     CDS             43086..43766
                     /locus_tag="VCR92_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEP4267675.1"
                     /translation="MDKETLNYWKTVITFLHDVLGDNYEIILHVIDKNDIYIGELVNS
                     HISGRSKQSPLTTFALDLITNKVYKEKDFVTNYKAIVSPQHKEVRGSTFFIKDKKGNL
                     EGMLCINLDISAYQGVARDLLKLVNLNLEHFIPTAKEPKTVTPQPEEAVEILTSNIQD
                     IIGQIIDPSLLRHNVHLSQDVKIDIVAKLYEKGVFQLKGAVSKVADILCISEPSVYRY
                     LKKIEADQ"
     gene            complement(43887..44534)
                     /locus_tag="VCR92_000586"
     CDS             complement(43887..44534)
                     /locus_tag="VCR92_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEP4267676.1"
                     /translation="MAVALSKEEIQNRIAKRVAKELEDGTLVNLGIGLPTKVANFVPE
                     EMTVYFQSENGFIGLGPKSDDPNSTIVNAGGQPVTVYPGAAFFNSADSFGIIRGGHVD
                     LTVLGALEIAENGDIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKHKLLKE
                     CTLPLTAKGVVDLIITEMGVFKVTPDGIQVIEISEGFTFDEVQAATGVPLSIAEG"
     gene            complement(44537..45196)
                     /locus_tag="VCR92_000587"
     CDS             complement(44537..45196)
                     /locus_tag="VCR92_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEP4267677.1"
                     /translation="MKENKRIAIAEAISHIKDGDTIMVGGFMANGTPEALIDALVDKG
                     TKDLTLICNDAGFVDRGVGKMVANHQFKTIYATHIGLNKEAGRQMTAGETTIELIPQG
                     TFAEKIRIGAYGIGGFYTPTGVGTLVAEGKETKTIKGKTYLLEYPFEADVTLIFANKA
                     DEMGNLQYSGSENNFNQLMAACAKTTIVQVREIVPVGTIQPECVHTPHIFVDYIVKEG
                     V"
     gene            complement(45208..46392)
                     /locus_tag="VCR92_000588"
     CDS             complement(45208..46392)
                     /locus_tag="VCR92_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEP4267678.1"
                     /translation="MTKEVVITSAYRTPIGNFGGVFKSLSAVDLGVTVVTKILADTGL
                     KSDAIDEVIFGNVLHAGLGQNVARQVALNAGLSYDTPAFTIDMVCGSGLKAVELGAQK
                     IQTGNADIVLVGGTENMSQAPYVLQGQRWGSRMGDSKVVDTMLKDGLSDAFAGYHMGI
                     TAENIVQQYGLTREEQDAFAADSQRKAQLAIEKGRFKEEIAPVTIPQRKGEPLLVDQD
                     EYPKFGTTVDKLAKLRPAFIKDEGTVTAGNASGINDGAAAILLMSKEKAEELGLPILA
                     KITSYASAGVDPSIMGCGPIPATKKALAKAQLTIDDIDLIEANEAFAAQALAVSRDLG
                     FDNEKVNVNGGAIALGHPIGASGARILVTLLAEMAKRDVRHGLATLCIGGGQGQSIIV
                     TR"
     gene            46513..47424
                     /locus_tag="VCR92_000589"
     CDS             46513..47424
                     /locus_tag="VCR92_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEP4267679.1"
                     /translation="MNISSLAYFIEIVNCDFNLTKAAQKSHISQPALSSYIKTIEKEE
                     GVVLFQRQKGRLVGLTSVGERFFENAKVVIASHEQLMADLRSESKKYKGEISIGIPQL
                     ISGIVFSELIPKLIEENPEAKFHIVETGAYELQKKLFLKEVDFAILLTPTTLDATIAD
                     IDILLRDQLCLYMSHKTFQETFDSNPNISIKALHRQNLVTFDKTFMINHQLTTLFEEA
                     NSLPVVKCYSASWDFLLNCTRYSSYLTILPRPITHFAHMDGLVEVQLTEHPKWEVVLA
                     SLKHNKTSHLKHYIKHTILDYFMNQRF"
     gene            complement(47494..48900)
                     /locus_tag="VCR92_000590"
     CDS             complement(47494..48900)
                     /locus_tag="VCR92_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain fatty acid transporter"
                     /protein_id="HEP4267680.1"
                     /translation="MNNIKTKKRFMDRYIDGFMKWMPESLFICFILTFLVVTMSVLMT
                     DSPFIGTEKTGGIIYGWVNGFWGLLSFAMQMTILLATGNAVASSPPAHKMFKSLAKLP
                     QTRTQIFIFSIVVGSIFGFLHWGLGMMVAIVFGKELLVQARQKGIKVHTPLFVATLFF
                     TFLPATSGLSGAAVLYSATPDYLRNSVADAYKQVVPESVPLTESVLNLPFISLLVVCM
                     LVPLCFALLAHPKDETKIMELDDEIYHHSLDTASHVVIARNTPAEKMNASRLVMYLVG
                     GAIVSYSLYHFSVVGLSGLDLNSFNFLFLGLGLLLCGQQGPEYYGSLFKDGVMSSWGL
                     VLQFPFYAGIFGIIQSTGLGLEISHFFVAISNGTTWPVFAYLYSALLNIAVPSGGSKF
                     VIEAPYIVPATIEVGNDLGKILQAYQLGDATTNLIVPFWALSYLSNFKLKFNQIVAYT
                     IPCVLVVTGIAIIYLFVF"
     gene            49253..49918
                     /locus_tag="VCR92_000591"
                     /pseudo
     CDS             49253..49918
                     /locus_tag="VCR92_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(50184..53678)
                     /locus_tag="VCR92_000592"
     CDS             complement(50184..53678)
                     /locus_tag="VCR92_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEP4267681.1"
                     /translation="MTQKNSYKLSFLLSLTGFILGLLLVFIGLSGVSVGHAETRNGAN
                     KQGSFEIKKVDQNNKPLSGATFSLTPKDGKGKPVQTFTSSEEGIIDAQNLQPGTYTLK
                     EDKAPDGYDKTSRTWTVTVYENGYTKLVENPYNGEIISKAGSKDVSSSLQLEKSTMSV
                     FSKYGGTEVTSGAADFYRNHAAYFKMSFELKQKDKSETINPGDTFVLQLDKRLNPKGI
                     SQDIPKIIYDSENSPLAIGKYDAKTHQLTYTFTNYIAGLDKVQLSAELSLFLENKVVL
                     ENQTISDFKSTIGDQEIKYGGTVNVLYGNASGQDNNYVTNGLSNVGGSIESYNTQTGD
                     FTWYVYVNPNRTNIPYATMNLWGFGRLVKSNNSTSKSEDSATSSAQLEKVEIYEVKED
                     YTLPTSYGVDLTKLNLRKDLEAKLPQDSTQNSNKRLRIDFGDKLQNKAFVVKITGKTD
                     QSGKPLVVQSNLASFNNETAVTYGNPVNNVYFQNEIALSPSKGSGSGTSEFTKPSITV
                     ANLKRVAQLRFKKMSTDNVPLPEAAFELRSSNGNSQKVEAKSNTQGEVHFKDLTSGTY
                     DLYEKQAPKGYQQVTEKLATVTVDTTKPAEEMVTWGSPHSSVKVEDSKEVTIVNHKET
                     LTFSGKKIWENDRPDQRPAKIQVQLLQNGQKMSDKVQEVTKDNDWSYHFKDLPKYDDR
                     NQEYKYSVEEVKVPDGYKVSYLGNDIFNTRETEFVFEQNNFNLEFGNAEIKGQSGSKI
                     IDEDTLTSFKGKKIWKNDTAENRPQAIQVQLYADGVAVEGQTKFISGSGNEWSFEFKN
                     LKKYNGTGNDIIYSVREVTVPTGYDVTYSANDIINTKREVITQQGPKLEIEETLPLES
                     GASGGTTTVEDSRPVDTLSGLSSEQGQSGDMTIEEDSATHIKFSKRDIDGKELAGATM
                     ELRDSSGKTISTWISDGQVKDFYLMPGKYTFVETAAPDGYEIATAITFTVNEQGQVTV
                     NGKATKGDAHIVMVDAYKPTKGSGQVIDIEEKLPDEQGHSGSTTEIEDSKSSDLIIGG
                     QGEVVDTTEDTQSGMTGHSGSTTEIEDSKSSDVIIGGQGQVVETTEDTQTGMHGDSGC
                     KTEVEDTKLVQSFHFDNKESESNSEIPKKDKPKSNTSLPATGEKQHNMFFWMVTSCSL
                     ISSVFVISLKTKKRLSSC"
     gene            54063..55268
                     /locus_tag="VCR92_000593"
     CDS             54063..55268
                     /locus_tag="VCR92_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEP4267682.1"
                     /translation="MVIFDLKYVQTLHSLSQLPISVMSQDKALIQVYGNDDYLLCYYQ
                     FLKHLAIPQAAQDVIFYEGLFEESFMIFPLCHYIIAIGPFYPYSLNKDYQEQLANNFL
                     KHSSHRSKEELLSYMALVPHFPINNVRNLLIAIDAFFDTQFETTCQQTIHQLLQHSKQ
                     MTADPDIIHRLKHISKASSQLPPVLEHLNHIMDLVKLGNPQLLKQEINRIPLSSITSS
                     SISALRAEKNLTVIYLTRLLEFSFVENTDVAKHYSLVKYYMALNEEASDLLKVLRIRC
                     AAIIHFSESLTNKSISDKRQMYNSVLHYVDSHLYSKLKVSDIAKRLYVSESHLRSVFK
                     KYSNVSLQHYILSTKIKEAQLLLKRGIPVGEVAKSLYFYDTTHFHKIFKKYTGISSKD
                     YLAKYRDNI"
     gene            complement(55427..56014)
                     /locus_tag="VCR92_000594"
     CDS             complement(55427..56014)
                     /locus_tag="VCR92_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HEP4267683.1"
                     /translation="MRKYWKMLFSVVMILTMLAFNQTVLAKDSTVQTSISVENVLERA
                     GDSTPFSIALESIDAMKTIEEITIAGSGKASFSPLTFTTVGQYTYRVYQKPSQNKDYQ
                     ADTTVFDVLVYVTYDEDETLAAKVISRRAGDEEKSAITFKPKRLVKPIPPRQPDIPKT
                     PLPLAGEVKSLLGILSIVLLGLLVLLYVKKLKSRL"
     gene            complement(56031..56756)
                     /gene="srtB"
                     /locus_tag="VCR92_000595"
     CDS             complement(56031..56756)
                     /gene="srtB"
                     /locus_tag="VCR92_000595"
                     /EC_number="3.4.22.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HEP4267684.1"
                     /translation="MMMTIVQVINKAIDTLILIFCLVVLFLAGFGLWDSYHLYQQADA
                     SNFKKFKTAQQQPKFEDLLALNEDVIGWLNIPGTHIDYPLVQGKTNLEYINKAVDGSV
                     AMSGSLFLDTRNHNNFTDDYSLIYGHHMAGNAMFGEIPKFLKKDFFNKHNKAIIETKE
                     RKKLTVTIFACLKTDAFDQLVFNPNAITNQDQQRQLVDYISKRSKQFKPVKLKHHTKF
                     VAFSTCENFSTDNRVIVVGTIQE"
     gene            complement(56772..57809)
                     /locus_tag="VCR92_000596"
     CDS             complement(56772..57809)
                     /locus_tag="VCR92_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QVPTGV class sortase B protein-sorting
                     domain-containing protein"
                     /protein_id="HEP4267685.1"
                     /translation="MKKNKLLLATAILATALGTASLNQNVKSETAGVSENAKLIVKKT
                     FDSYTDNEVLMPKADYTFKVEADSSATDKTKDGLEIKPGVTEGLTTEQTIAYDNSVKP
                     SDKSKTATFDFSTVKFPEVGVYRYTVSEIDSKVSGIKYDTKTWIVDVYVVNDGNGGFK
                     ARYIVSKEKGQNDKKPVVFENSFKTTSLKVEKQVTGNTGELKKDFNFTLTINPNDNFV
                     AGQVIKLEKGGIKADVKIGEPYKFALKNGEKVTLSKLPVGVTYSIIEDEADKDGYTTN
                     AKITDGTAAPVEYKLGNQQLADESADEIVVTNNRDTQVPTGVVGTLAPFAVLSIVAIG
                     GVIYITKRKKA"
     gene            complement(57831..58352)
                     /gene="lepB"
                     /locus_tag="VCR92_000597"
     CDS             complement(57831..58352)
                     /gene="lepB"
                     /locus_tag="VCR92_000597"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEP4267686.1"
                     /translation="MTNYLNRLNENPLFKAFIRLVLKISIIGFLGYILFQYVFGVMIV
                     NTNQMSPAVSAGDGVLYYRLTDRYHINDVVVYEVDNTLKVGRIAAQAGDEVNFTQEGG
                     LLINGHPPEKEVPYLTYPHSSGPNFPYKVPTGTYFILNDYREERLDSRYYGALPINQI
                     KGKISTLLRVRGI"
     gene            complement(58345..60588)
                     /locus_tag="VCR92_000598"
     CDS             complement(58345..60588)
                     /locus_tag="VCR92_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus ancillary protein 1"
                     /protein_id="HEP4267687.1"
                     /translation="MNNKKLQKKQDAPRVSNRKPKQLTVTLVGVFLMLLVLIGFEGKV
                     RAAHELVEVPVPIFHNPDPQSDYQWYGYEAYTGGYPKYDLFKTYYHDLRVNLHGSKSY
                     QVYCFNVHKHYPRSSQSFDRKWYKKLDGTAENFDSLAMEPRVRKEELTKKLLAVMYNA
                     YPNDANGIMKDLEPLNAIKVTQEAVWYYSDSAQINPDESFKTEAQSNGINDQQLGLMR
                     KALKELIDPNLGSKYSNKTPSGYRLNVFESHDKTFQNLLSAEYVPDTPPKPGEEPPAK
                     TEKTSVIIRKYAEGDYSKLLEGATLRLTGEDIPDFQEKVFQSNGTGEKIELSNGTYTL
                     TETSSPDGYKIAEPIKFRVVNKKVFIVQKDGSQVENPNKEVGSPYTIEAYNDFDEFGL
                     LSTQNYAKFYYGKNYDGSSQIVYCFNANLKSPPDSEDHGATINPDFTTGDIRYSHIAG
                     SDLIKYANTARDEDPQLFLKHVKKVIENGYHKKGQAIPYNGLTEAQFRAATQLAIYYF
                     TDSVDLTKDRLKDFHGFGDMNDQTLGVAKKIVEYALSDEDSKLTNLDFFVPNNSKYQS
                     LIGTEYHPDDLVDVIRMEDKKQEVIPVIHSLTVKKTVVGELGDKTKGFQFELELKDKT
                     GQPIVDALKTNNQDLVAKDGKYSFNLKHGDTIRIEGLPTGYSYTLKETEAKDYIVTVD
                     NKVSQEAQSASENVTADKEVTFENRKDLVPPTGFTTDGGTYLWLLLLVPFGLLVWFFG
                     RKGLKND"
     gene            complement(60874..61722)
                     /locus_tag="VCR92_000599"
     CDS             complement(60874..61722)
                     /locus_tag="VCR92_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEP4267688.1"
                     /translation="MTERLKNLGILLLFLLGTAIFLYPTLSSQWNAYRDRQLLSTYHK
                     QVTQKKPSEMEEVWQKAKAYNARLGIQPVPDAFSFRDGIHDKNYESLLQIENNDIMGY
                     VEVPSIKVTLPIYHYTTDEVLTKGAGHLVGSALPVGGDGTHTVISAHRGLPSAEMFTN
                     LNLVKRGDTFYFRVLNKVLAYKVDQILTVEPDQVTSLSGVMGKDYATLVTCTPYGVNT
                     KRLLVRGHRIAYHYKKYQQAKKAMKLVDKSRMWTEVVCAAFGVVIAIILVFMYSKMTD
                     KKVIKN"
     gene            complement(62010..63680)
                     /gene="sfbI"
                     /locus_tag="VCR92_000600"
     CDS             complement(62010..63680)
                     /gene="sfbI"
                     /locus_tag="VCR92_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein SfbI"
                     /protein_id="HEP4267689.1"
                     /translation="MNNKIFLNKEAGFLAHTKRKRRFAVTLVGVFFMLLACAGAIGFG
                     QVAYAADEKTVPNFKSPDPDYPWYGYDAYTGAFLRYHDLRVNLNGSRSYQVYCFNIKK
                     NYPRPFTSSDKKWYKRLEGTAETFKVHAMAPRVGGEELTKKLRSVMYNGYPNDGNNIM
                     KGLEPSNAIEVTQYAVWYYSDKSQYEIETLWKSEAKEGKISESQVTLMREALRKLISS
                     DEDLVKQVPSNFKLSTFESSDKSYQNLLSAEFVPDDPPKPGDTSEHNPKTPELDGSPI
                     PEDPKHPDDNLEPTLPPVMLDGEEVPEVPSESLEPALPPLMPELDGEEVPEVPSESLE
                     PALPPLMPELDGQEVPEKPSVDLPIEVPRYEFNNKDQSPLAGESGETEYITEVYGNQQ
                     NPVDIDKKLPNETGFSGNMVETEDTKEPEVLMGGQSESVEFTKDTQTGMSGQTTPQVE
                     TEDTKEPGVLMGGQSESVEFTKDTQTGMSGFSETVTIVEDTRPKLVFHFDNNEPKVEE
                     NREKPTKNITPILPATGDIGNVLAFLGILILSVLSIFSLLKNKQNNKV"
BASE COUNT        18981 a        13577 c        11319 g        19816 t
ORIGIN      
        1 tcaaggtaat agactctact ccttgtaagt ctaacttatt cttaatctta tttatcgctc
       61 attttttaaa ttccgatgct ctcacagata ttatcattgt ttagttacat gtctgtcaat
      121 ctattcgcca ccacactagg ggccatctga ttgaaaaata aaatttcgga gtccattgtt
      181 tgctcaagaa tcatatctgt cacaattacg tcatactctg aagacagtga caccatatca
      241 accatggtca gcctcaagtc atcaaagttg ataatctcaa aaaatcctcc aaaatactct
      301 tttaagaagt tgccaacatt gttataactt ctctcaacca ctaatagttt caagcgacga
      361 cgcgattgat ttgtaagaaa gagattttcc caggtgagga acaaacaaat agaggagatg
      421 attgatggtt ctttccttta attccttatg atccccagca aataactctt taacataagc
      481 aacaaaggtc tggtattgaa ctgggggttt ttgatttgta aaggcactat atttataatg
      541 cctttattta agggttaact ctaaaaatca gattggtctt ttgcttggca atccggacaa
      601 atcccgtaag caataactgg gatacgcgtg accttataac ctgtttgctc atgggcttct
      661 ttggcaatat ccataacatc aacatccata aagtcagcaa tcttcccaca tatttcacaa
      721 accacattga cgtgttgatg gcccataaag tcatagtagg tggttaaatc attgctgatt
      781 ttcaactctg agacaaaacc ttcatcaact aaaactttca aattattata gactgtggca
      841 aggctcatgt taggaaagtt aggctgtaag tcacggtaaa tcttatcggc actagggtgt
      901 tctgtggact gaatcatgta agaaataatg gctttacgtg tctctgtaat tcgaatatgt
      961 ttttcccgta gatgctctag gacattttca taggcatcta gggcttgctg atgtgaatga
     1021 atgtccataa gctgctactc ctatcctttt ttcctttatt atcacgcacg tctctagttt
     1081 caaagatttg tgatgcattc tggtttagcg actaattgca aatagtctat ttttaggcag
     1141 cgattcatca caatagcctc tttgcctgcc gaccgtaaaa tggtttgtac ttcttggttt
     1201 tcaaggccta attgcgccca aaagactttg gcctgacctg ctaaaaagtc tctggcaact
     1261 tctggtaaaa actcacttct gcgaaagaca tctacaatgt caacctcaaa gggaattgcc
     1321 ttgatactgg catagacctt ctctcccaaa ataagctgac ctgctaattt gggattgact
     1381 ggaatgatcc gataatccat agcctgcata aatttggcga caccataagc tgctgtgtct
     1441 ttgcggtcag aaagaccaac aaccgcaatg gttttggctg actccaagta agcttttagg
     1501 atatcctctg agggattttg aaacgaataa atcacttgtt cccctatcta tttaataacc
     1561 tctacagctg ttcaatatag caggataact cctaaagcat ggcttcaatc acttttaacc
     1621 ttatccgtca aaaagctcaa agcagcttca tgacttctcc tacaattttt tagtttatta
     1681 taacataagt tgtcaaaatg agaaataaca agtaagaaaa cttatttggc ttcgtaccag
     1741 ctctgcccag tactttcatc gacacataaa ggaacagcta aatcaacagc agcttccatg
     1801 gtgtctttga caagtttttt tatagcagtc aactcatcat ttggcacttc caaaacgatt
     1861 tcatcatgca cttgaagcag cattttagct ctaaaaccac ctgcttgcaa ggccttatcc
     1921 agattaatca tagcgatttt gagaatatca gctgcgcttc cttgaatggg cgagttgatg
     1981 gctgtacgct ccgcaaaaga gcgaacgttg aaattacgag agttgatatc cggtaattca
     2041 cgacgacgct taaagagggt ctctacatag cccttgtctt tagcctcacg caccacattt
     2101 tccatatagg ctttaatccc aggatagcgt tcaaaatagg tatcaatgta agacttggcc
     2161 tgtttacggg tgataccaag gttatttgac aaaccaaaat cagaaatccc atacacaatt
     2221 ccaaagttaa cagccttggc attacggcgg tcattggcag taacatctgc tgccttgtca
     2281 atcccaaaca cacgcatagc cgttgaggta tgaatgtctg ccccttcatt aaaggcagca
     2341 atcaaatgct catcccctga aatatgtgcc agtacccgca attcaatctg tgagtaatct
     2401 gaactcaaca agacggcatc ttcatgagat ggggtaaagg ccttacgaat caaacgcccc
     2461 tgttccaaac gaatgggaat gttttgaaga ttagggtcca cactagacaa acgccctgtc
     2521 tgggtgagat cctgcacata gcgggtatga atcttgccat cagccagaat ataatcctgt
     2581 aaaccaatca cataggtgga ttgcaattta gtaatctggc ggtaatccaa aattttagcc
     2641 acaattggag caatcggtgc caaacgttcc aaaacatcaa cagctgtaga ataacctgtt
     2701 ttggtcttct tagtcatctc aagaggtagt tgcatcttct caaacaagat actgcccagc
     2761 tgtttaggcg aattaatgtt aaattcttgg ccagccatat cataaatctc ttgggtgagc
     2821 gcttcaataa tgaccttgtt ttgctctgcc atatcttgca aagtcgccct attaaccttg
     2881 atcccttcaa tttccatttt agcaaggaca ttagccaaag gcaattcaat attctgatag
     2941 aggtctagtt gctcatgggc agtaagcttg tctagcattt gagacttgct atctaataat
     3001 actttgacct tacgagctaa gtgttctagt aaaacgtctt tatcaggaac agcccgttta
     3061 gcacctttac catagactgt atcgtcttct tccaaagaga tgtcagtaaa aatgcgggca
     3121 atggtgctaa gctcattgtc ttctacagtt gacagaaggt aattagctaa tctagcatca
     3181 tagctaggtg ctaccaactc aattcctaag tggctcaaca agaccttgct acgtttaaaa
     3241 tcataagtgg caatgggttt ttggaagacc tgcttaaaac tatccgtcgc taataggcta
     3301 aggtcagtgg atgcgtaaat ctgctcacca tgtccccaag caaaaccaat gatggcctca
     3361 caatggtaat tatcccgaag cgtttcaaag tagaagatgt cttctgcgct aaacaaatca
     3421 gcagacacat tggtcacttc ttgataggaa atggcagcta ctggctcttg aggcatctgg
     3481 ctagcaagac ctttcttgag ttgcacaaaa tccatctcat cgtaaaattg agagaggcta
     3541 gcaacatctg gaccattgta gacaatatca tctaagccaa ttgtgatagg agatgctgta
     3601 ttgatagtgg cgagcgtttt agataggaaa gcttggtcac ggtcattgat caagttttct
     3661 ttcatttttg aggccttgaa tccatcaata tgctcgtaaa tgccttccaa actaccaaat
     3721 tcatgaagga gcttgagccc agttttttca ccgattttgg tcactcctgg aatattatcc
     3781 gatttatctc ccatcaaggc tttgaggtca ataaactggt ttggcgtcaa gcccattttt
     3841 tccatgaggt aagccggtgt gaattcttca aattcggcaa cccctttttt agaaatttca
     3901 accacggtat tttcgtcagt taactggatc aaatctttat caccactgac aatggtcaca
     3961 tcaaaaggca cttctgtgcg ctccgccatt ttatcaagcg tcccgataat atcgtctgct
     4021 tcgtagtgtt ccaactcata ataagcaatc ccaagggctg tcaacatctc acgaatataa
     4081 ggaaactgct cacgaaattc ctctggtgtc ttggcgcgac ccgccttata atcggcatac
     4141 atttctgttc ggaaggtggt tttgcccgca tcaaaagcca ccagcacgtg agtaggctgg
     4201 actcttttca tcatgtggtc tagcatcaaa tgaaagccat aaatggcatt ggtatgaaga
     4261 ccgctatgat ttttaaagcg gtcaatttga ttgtagaggg caaaaaaggc acgaaaggca
     4321 acagatgagc catcaattaa tagtaattta ttcttgtttt ccatagcctt attataacac
     4381 agagggacgg gcttttctcc tttaagccat tggttttgct gataagtaaa tagttaacct
     4441 aaaaagccta ggaaaattcc tagacttctc tatttgctat ttagacaaaa gcacttattt
     4501 tgtccaactt gatactttag attggtttgc ctctacccat tttttggcgg cagcttctgg
     4561 gctcatgcct ttgttgatgt caagcatgac tgcttccata tctttttggg tccagtggaa
     4621 cttatcaatg attttgtaga catttggaag atcttttttc aagcctttac gagcaatggt
     4681 attgatgttc tcagtcgagc caaaggtttc tttaggatct ttaaggtact tcaagtcata
     4741 cttggcaaac atccagtgtg gtgaccaagc tgtcacgaca ataggatctt ttttcttgat
     4801 cgcttgatcc aaggaagtcg tcatggctcc tgttgatgcc gccactaact cccaactaga
     4861 tagattatga tactctttta gagtcttttg ggctgctgcc atgatacctg cacctggttc
     4921 gatccctgtg attttttgat cggcttgttt gcttaagtcc tcaatactat taacatctgt
     4981 catgtatttt ggaacagcta aaccaagttt ggtccctttt aggttaggtc ctaaatcatc
     5041 taattttgac ttgtatttct gatattgttg gccatgggtg actggcaacc aagcactagt
     5101 tgaaaaatca gcgttcccat ttgcaacggt ttgccacata acggcattgt caagcggagt
     5161 caaggtcaca tggtaacctt cgtttttcaa aacttctgca atcacatgag ttgaggcaac
     5221 ctcagaatcc cactgcacgt aagcgatgtt aacagtttca cccttatctg ccataccaga
     5281 agtcatagcc ataataccgc gtcctaaagc agctatcaaa aagacagcaa gggctgctag
     5341 accaatccat ttattggttt tgccagcttt ggctttttct tgaggtttgc tattgaacaa
     5401 ctgtgtcata cggtcaagca caatcgccaa gataaccaag gcaagaccac tgacaaatcc
     5461 actaccaaca tcagcgtgtt gaagggctga caagacttca cgtcctaagc caggagcacc
     5521 aatcatggag cctgttacta ccatggaaag ggctaacatc atggtctgat taacacctgc
     5581 cataatagta tttttagcta aaggcaattc cactttaaag agcttttgtt tcccagttga
     5641 cccaaaggca tctgaggcct caatcaattc tgttggaatg tcacgaatgg ccaaatttgt
     5701 aaaacgaacc gttggaggca aggcaaagat gactgaggca aacactccag gcaccatacc
     5761 aataccaaaa aaggcaacgg caggaatcaa gtaaacaaaa gccggcatgg tttgcataaa
     5821 gtccaaaata ggattcacaa tctgacggac agtggcattt ttagccatcc aaatccccag
     5881 cggaatacca ataagtaccg aaatcaaact agctactaac accagagtaa aggtattcat
     5941 tagctgcttc cataaccctt gattgtaaat aaagagcaat cctaacaagg taaaggttgg
     6001 caaaggccat tttttcttag caaggaaaaa cacccctgct gttactagaa caataaaaag
     6061 taacgggtgg ataaataaaa gtgttttggt catccaatcc atcaaaaagc taccaactac
     6121 ttgcataata tcaaatagac ctgagaaagt tttagttagc cactccgtta gctgctccac
     6181 cagttgagct actggtaatt ttgtttgtaa tatcgtttcc aaaatgcatc actcctttta
     6241 gttaaggtct tcgtctgaga tattagccaa ggcttcaatc actcgtcctc gaataatgac
     6301 acctagcaga cgattattat catctgtcac tgcaatcgga gcagatgaat catagataag
     6361 aggcaaaata tctgtaataa tagtatcttt tgagacagtt ctcacatcgc gatcaatcac
     6421 ttctgatagc ggtaaccctt ttttgcgcgc ctctatagcg gcatcggccg tcaaactacc
     6481 gactaattgg cggcggcgat tcgtcgccat caacatagac acctcttcgt tgtgcatacg
     6541 gttcaaggca acttgaggtc catctaattc aacagtagtt gttaacggtt tgatcatgat
     6601 attttgtgct gtcaagactt tagaacggtc cacatcctca acgaattcac gcacaaagtc
     6661 attggctggg ttagtcaaga tttcctcacc agtaccaatt tgcataattt gtccgtcttt
     6721 catcaaagca atccgatcac caatacgcaa agcttcattc aagtcatgac tgataaagat
     6781 gatggtttgt ttcatgctgt cttgcaaatc aagtaattca tcttgcatct cacgacgaat
     6841 caaaggatca agcgctgaga atgcctcgtc cattaagaga attttagggc tattagctag
     6901 cgcacgggct aggccaacac gctgctgcat cccaccagat agttggtttg ggtactggtc
     6961 tttaaaatct aataggcctg aattatcaag ggctttttct gccaatcgct ggcgttcttc
     7021 tttgggaacg ccacgtaatt ccaaaccaaa ttcggtattt tccaaaatgg ttttatgagg
     7081 aaagagggca aagctttgga aaaccatgtt aatgtcatgg cggcgcacct cacgcagctg
     7141 atctgctgac atggttgaga tgtctttacc ttccagcaag atagatcctg ctgaaggttc
     7201 aatcaaacga tttagcatgc ggacaagggt tgatttccca cttcctgata gccccataat
     7261 aacaaagatt tcaccttttt tgacctcaaa actagcgtca tagacaccta cagtagcgcc
     7321 tgttttctta aaaatctcac tcttattttt gccagtcttt accatctcaa gagctgcttt
     7381 ttgttttttg ccaaaaattt tactgagatg tttgacttct aaaattgttt ccattcgttt
     7441 tttctcctag gtaatcgttt attatgtgaa atagtgacat agctttggcg aaatattagc
     7501 caatatttaa caaagtagct ctacacaatt aataaacgtg tggtcacttt tttacttaaa
     7561 aaaagaatct gccgaaacag aacataacta tattatcacg tgtggtcact ttttgtcaag
     7621 gacaataact cgatctgtaa taccacaatg ataggtgatc gctttcattc ttttaggtat
     7681 ggtcttttaa ccagtacaat tttttatcac aactgatgac tatttctttg ctgattaggc
     7741 tattgttaca ttagaaatcc ttcttttacc tataatatct cttttgcggc catcgtaaat
     7801 aacgaccacg gtgactctta aacatttgct catctctcca aaaaaactca cctaagacag
     7861 tgtcctatga agcgagttag cttaatcagg cactatcatc ttaggtgagt agggtgttgc
     7921 ttatagtaaa gctttaaatt ggatattaga atcttctaag aagcagtcat caaatccacg
     7981 aggatgatgg tattcgatac gattttggtc ttgtggatag gtgtacttgc caccaacctc
     8041 ccagataaag ggatggaaat cgtattggag acgttctttg cgcattttcc acagttcaag
     8101 gatttcatct gttgatgcca taaagtttga ccaaatgtca taatgaactg ggataacgac
     8161 tttagcacgg agattttctg ccatacgaag aaggtcaaca gaagtcatct tgtcttgaat
     8221 cccaattggg ttttccccat agttatttaa cacaacgtca atatcataat cacgtccatg
     8281 tttagcaaag tagttcgaaa aatgagaatc cgcaccatga tagatggtac cacctggtgt
     8341 ttcaaaaata tagttaacag ctttgcgagc catgtcatca tctgtgatag ctaaacctgc
     8401 taaatcacca tcttgagcat cagctccttg tattgggaga gttaccagac aggtgcggtc
     8461 aaacgactct acagcggtga tcttaatatc tttgaattca aagctatcac ctggctttaa
     8521 gatcataata cgatcttttg gcacacccca atttttccaa acttcaccac attcataagg
     8581 tcctacaaat ttaacatgat taagttttgg gttattgata atggctgccg cagtattgat
     8641 atcgatgtgg tcactatgat aatgagaaac caaataataa tccaactcat taatcataaa
     8701 tggatcaatc accattggtt gggccctaag attgggctgt aatttacgag ctcctgccat
     8761 attagccatt tgatgtccac gaaccatatc cttaacttgc ttggtcgctt tcccacgatt
     8821 tgaccataag tccatgacaa cattagcacc gcctggtgtc ttaatccaga taccacagtt
     8881 tcctaaccac cacatcgcaa agttgtcagc tggcacgact tcttgctcga tttcttcatt
     8941 taaccatgtt ccccattctg gaaacgtgtt aaggatccat gattcacgtg taatatcttg
     9001 tactttagtc attagggttt cctccgaatt tgttcttcgt ttctatactt taagtataga
     9061 ctttcttgtc aatgataaaa agaccaagtg tcacacagat ctgtgttcaa aagtggactg
     9121 actttttcat tagctcagtc taatactgtc tcattttgca cactgtatct cgcatcaata
     9181 ctgtattcaa agctatatta aaaacctcag ttatattttt ctatgtcata gaaaactgag
     9241 gtactttgac gacttaacac ttactcatag cagctcgcga tgaatgagtt tttcaatttt
     9301 agaaaccaag gcataacgat ctgattcatc ttttacaaca gcttcaatag cttttgtgag
     9361 ctctgtagaa aagcgggagt gctcactcaa gcgtccttgc tttgaaaagc gtatcaattt
     9421 gatgatatca tcgtcactta aaatagggtt aacaataagc atcgggattt tagtctttag
     9481 cgtatctgta gtagcaacaa tcatatcgac tgctaaaagg tcgtaaacac tctgatactg
     9541 ttctgtcgta aaaacagctt caatctgacc atttgctaga tacctttgac actgtttgaa
     9601 caataacttt tgaatgccta tcccatcatc tgaaacaata acgagtttgg tcttttcttg
     9661 ctctgtatta ttgtgacgca gctctccccc aagatggata gtcaagtagg caatatcatc
     9721 gtctgtcaag ctaatcgtcc aatcttgttc caaaatagtg gcacaagatt gagtcatagc
     9781 aaacaattct tcgtattttt ctttaatatg gtctgttaag ggattaacta aaaaaatccc
     9841 ataagcttta cggtaaacga gcgccttaca gtgggtcgtc aactgcttca gcaaatcctg
     9901 tttatgcgtg aaatgtaact gataacggct ctccaactgg tcaataaagt gactaatggt
     9961 tgctcgcatg tcgtcataat cttgactttc cacgtgatga tcttgatctt ttcgaaaaga
    10021 caacatcaac atcgctacca tactaacttc gatatcatcc aaatgaagct taaaattatg
    10081 gtaaagctct ctagctaaat cctgagcaat gtgatattct ttacgtttcc aaatcaaatg
    10141 aaattcttgt ttaagagcag actttgtttc tgaatcaaga cgcatattac gataacttaa
    10201 aagcatgaaa ggtaaaatct gcaacatgaa ttggctatct tgggtattaa ttgtctttcc
    10261 taagctagct tgagataaaa agagatactc atgaaaataa gtcaaaatat ctttagaaaa
    10321 ataaaccgat aagccttgta tctctgagag tttacggttg aatatatcaa taaagctagt
    10381 attgccacct tggtaaacgt ccactaacaa tttgtacagg tattgaataa gagccattgg
    10441 atgacaacca aaataatatc ccctagcctt tgtcgcatga agctgaatct tgtattgttt
    10501 gtcttccagt tcttccctta actcagtcag gtcatttaaa atcgtgttac gagacacatc
    10561 attgatctgc atcagtttat caatggtcac gcgctcagtg gaaaccgcaa tataaatcga
    10621 ggataggcgt ctgcgctcat cacttttcat gacataatta taatcagtca cttcttctaa
    10681 taataagcga caagcagctt tttgatcagc tgttaaaaga atgccaagtc taggataaga
    10741 gataatctga tctactccct ttggcaaagc cttattaatt ttgtcaagct ggtaataaac
    10801 tttacgacgt gactgattta aagcatgaga aatggccata actgtctcag gtgtttctag
    10861 tttaagtaaa taagacagca agtcataact ctttttatct aaaatcatca tgattacaaa
    10921 cctcctctct gaaaatccat ccttgcttat tttatcatga tttcagtgac tgcgcagcca
    10981 agttttgaaa aactcaccat aataagattc gcttaatatg attcgagcta atcacctcaa
    11041 ctgatccaac accaacacct tatatctggt ctctaagaac tccacaacat acgattcatc
    11101 aagtttgtgc tcattggcgt ttaaacagtt catcgaaaag gacaagtcaa aaggacttgc
    11161 ccaaacaatg attaacaaaa ccttgaactt tctggcttct agtgagaacc tgtgctaata
    11221 agccatatcg tgacctcatt tttgaccgta ataagcattt gggccatgtt tacgcaaata
    11281 atgcttatcc ataatgtatc gtggcgctgg ctctacgcgt ggattgattt gttctgtcaa
    11341 gcgattcatt ttagccactt cttctaagac aaccgagtgg taaacggctt gctctggggt
    11401 tttcccccac gtaaatgggc catgattgcg aaccacgatt cctggaaccg ccataggatc
    11461 taagcctcgc ttgctaaact cttctaaaat cacgttgcca gtttcttgct cgtaagcccc
    11521 atcaacttct gcttttgtga gagaacgagc acacggaact ggtccataga agtagtcagc
    11581 atgcgtagtc ccataaaacg gaatatcacg acctgcctga gcccaaccaa cagcttctgt
    11641 ggagtgagtg tggacaatac cgcccacttc tggccaagct ttataaagtt ccacatgggt
    11701 tggcagatct gaagaagggt tcaaatcacc ttcgaccaca ttcccatcaa ggtctgtaac
    11761 aaccatgttt tctggtgtca agaggtcgta gtccacccca gaaggcttga tgacaatacg
    11821 tcctaattca cgacaaactt cagagacatt gccccacgta aatttgacaa gaccgtgttg
    11881 tggtagagac ttgttagccg cacagacacg ttcacgcatt tcttgcaagt ttttcgccat
    11941 attatgccaa ccccgctttc tcaataagtg ggtaaaggaa gtcctgagct tctttgatag
    12001 cagcttttgt ttcctccacc gtgtcacaat tttctgacca catttcaatc aaaaaaggcc
    12061 cattgtagtt ggttttcttg aggaccgcaa acagctcttg ccagtccaca caaccttgac
    12121 caaatggcac atcacggaac tgcccttttg aggtttccgt gacagcataa gtatctttca
    12181 agtggagagc tgcaatggac ttgtgaccat tgtaaaattc actccacaaa tcgttatgcc
    12241 aggcagaaac attgcctgca tcaggataaa caaagagata aggcgagtca atctcttttt
    12301 caactgccaa gtatttttca atagagttga taaaagggtc atccataatc tcaatagaaa
    12361 gcatcacttg ggcttcttcg gcccagtcac aagattgtct caagtttttg ataaaacgag
    12421 cacgggtttc aggcgatttt tcttcatagt aaacgtcata accagctaat tgaatggtac
    12481 gaacgcctaa gtcctgtgcc aattcaatac attgtttcat cagtttaaga gacttggctt
    12541 cagtagcagg atcatttgag cctagtgggt aacgtctatg accagaaaaa caaatggtcg
    12601 ggatgcgaat gcctgtttca taaatggctt tcactaaatc aagccgttct tccttagtcc
    12661 actctaagcg cgctaagcga gcatctgatt catcgacaga catctccaca aaatcaaaac
    12721 ctaagtcttt tgcaaattgc aagcgttcac gccaggtaaa ctgttttggc gttgcttttt
    12781 cataaatacc aataggacgc gccataaagt tacccccaga tacgtttgat ttcatctttg
    12841 aaggcacgcg ccgctgcagc aggatcttct gcttcagtaa tgcctcgccc tgcgataaag
    12901 gtaaagacat caaccccttc aaaaagtttc aaagtgtcta catcaagccc accagttact
    12961 gagacacgaa agcccatgtc aatcaatttt ttcaccttgt taaggtcttt ttcaccccaa
    13021 gtttctccag caagaagggc atcacgagat tggtggtaaa tcgcttggga aatcccagcg
    13081 tcaagccata attgagcttg ctcataagtc caatcaccat aaagttcgat ttgaatttcc
    13141 ccacggtcac cgcgctcttc tttaatagcc ttgagggctg cttccatggt tggaatcgtc
    13201 gcacagcaaa tgcaggtcat ccagtcagca ccacgttttg cattgttttt agcgaccgta
    13261 ccgccagcgt cagcacattt ggtatctgct acgataattt tctctgggaa gaggctgcgt
    13321 aatacctcaa ctagttcgct tcccacttga agcaaacaaa cggtaccagc ttcaatcaca
    13381 tctacttcgt gacccacagc aacggctgct ttaacagccc cctgtaagtc agaatggtct
    13441 aaagcaactt gtaaatttgg aatatgtgtc atctcttttt cctaaaactc ttagccaccg
    13501 tgcaaactgg ttaagagttc ttatcctttc aataatgatt gtgagtcgtt ttatccgttt
    13561 aagtcagtaa gctatcgatt aagcgtctaa atccaaacct tctaaatacg ggctattttt
    13621 tgattcttct accatttcta gaacctcttt aggactttgg caggccacca agcgttcaat
    13681 ggcgttatct agttcaaaca aggccacaat ttgtgggata gccactgttg tgtgaataga
    13741 agggtctgta gcggccaacg tcaaaagaac agaaacctct ttaccatctg agaaggtgac
    13801 tggttttgtt agtgtaatca aagcaaatgc attgcgatta acgcctaaac ctgcttctgc
    13861 atggggcata gccatacctg gcatcaacac ataataaggg ccgtattttt ctgttgatgc
    13921 aatgatggcg tcgtagtaag ctgacgtcac tgctttgcta tcaatcaaag gttgaacagc
    13981 taattgaaca gcctcttgcc aagtatcagc acttagcccc aatcggatgg agttgttgtc
    14041 aataaaggct tgttttaaat tcataaaaac tatctctttc tagtgtcttg ctttgcaaca
    14101 cacaccattt ttactagttt tatcctacta aagagaaaga gctgaaaacc ttcgtcacaa
    14161 ctccttcgtt ttgattcaga attagcttat agcacttctt gtagtttggt tttaatttca
    14221 ttatcatcca tcaggttatc aagaccaacc aagtgacctt tggtacgacc atcaagctca
    14281 tgaatcaagt ggtttgatgc cactacaata tcataaccag aagctagacc tttagcttca
    14341 ccaactgagc aagaagctga ctgaatatct gtcacaccaa gttgacgaag cgcattttca
    14401 actttcattt tgatcaccat agatgacccc ataccattgc cacatgctgt taatacttta
    14461 accattgttt tttcctccga aaatgtttta ttattatttt gttagaatag cagagctatt
    14521 tcttaagatg cagtgttatt gagcttcccc acggtaataa gcttctttgt ccttagcttt
    14581 tgcgaattgc aattgtggaa tggcaagtaa gaagatgcaa acaagcacat accctgcaat
    14641 accaaggaat ttgaagaggt acccaaatgg taaccatgga agaaccaagt cgatattacc
    14701 gtgataacca cctgtaagtc ctaaaagacc tacagcaaca gcaccaagtg caacttgcaa
    14761 aatacctgag ataaatgata gagctaccgc tgctttccag ccaccacgtt tatctgcata
    14821 aaccgcaatt gccgcattat caaagaatac gggaacgaat cctgtgataa ttaagattgg
    14881 atttttaaag ataacaagaa gagcaatggt gattaattga ccaatcaaac caaaggcaaa
    14941 tcctgaaagc accgcatttg aagaaccaaa gccataggaa gctgcaacgt caaccgctgg
    15001 gaatgaccct ggaagcaatt tgcttgagat cccttgaaag gcattggtca actcagaaac
    15061 gaacatacgt acaccttgca tcaaaatgaa gaggtaaaca gagaaggtga gtgatgtttg
    15121 aagaatatac atgaagaaag cttgcttagc tgggttgaaa gcgcctggtc cgattaactc
    15181 tacattagac atgatgtctg gaccaaggac agccaagata gctccaaaga agactaacat
    15241 taaggttgct gacgcaacaa cggtatcgtg gaaaatattt aagaaggttg gtaattttaa
    15301 gttatcaagg ttttcttctt ttttaccaaa gattggagca accttatcca caaaccaaat
    15361 cgcaaattgt tgttggtgac caatcgcaaa gccaccgcca cctgttaggc gttgtgttgc
    15421 ttcaaccgtc atgtttgagc tgactgccca gtaaagacca cagatgatac caaccgccca
    15481 agcaccaaaa gcattttgga attgagggat taaaagaagg acaaagaccg aaatcgtcgc
    15541 tgcctgttgg accatgatgt gacctgtgat gaaaagggta cgaactttag tgaccttgcg
    15601 aagtgcaacc aaaagaatgt tgaccccaaa tccaatcaag agagctgtcg tagcaacact
    15661 gatgaagccc atctcttcta acttagtatt agcagcagcc aaaccaaaat aaggatcaat
    15721 aacggcggct ttcaattcaa atttcttggc aagagcaacc aagatcggac gaaaagtcgt
    15781 tacaagaccg cctgctccaa cgttcaaaat caagtaacca acggtagcct ttacaaaacc
    15841 agcaaagacc tcataaatgg gttttttaag gagtaaatac ccgattaaaa ccaaaagacc
    15901 tacaaagaac gctgggtttt gcaaaatatt ttgcgagaac cagtttaggg gagctaggag
    15961 catttccata agaactacct cttttcaaag ttaataaaga taaagtgttt atatgttcat
    16021 tataggtaat gaaagcgttt taaaaaagac caactatcac acaaagaagt gttcaatatt
    16081 agacttaagt taacttattt taaaatttaa ctacacttaa taataaggag gaaatacccc
    16141 taaacaacga ttaaaaacca caagaacctt cgttcttgtg gtttttctag ataagttgct
    16201 ttttgaatag atcagctctt tggcattaac tgtgacgtga cgcaaataac cactgaaggg
    16261 ctgtgtcacc tcaaactatt tgataacaat attaacgagt ttgtttggta ctgcgatgac
    16321 tttgatgatg tctttgcctg tgatttcggc ttggactttt tcgttagcaa gggcaacttc
    16381 ttgcaattct tcgcgtgaaa ggtctttagc aacgacaagt ttagctttga ccttaccttt
    16441 gatttggaca acgatttcca catcgttttc aaccaatttg cttttatcat aacttggcca
    16501 tggcacgtaa gagattgact cacctgaggc tgtcaaggct tgccagagtt cctcacctaa
    16561 gtgcggtgca aatggtgcaa tcaattgaac aaagcctttg gcatagtcgc taaagagttt
    16621 gtcttccttg ttggctgcgt tgacaaagac catgagttga gcgatagctg tgttgaattt
    16681 catttggtca acttgctcag taacggcctt aacggtttcg ttgtaaacct tgtcaagagc
    16741 tccgctattt tcctcagtga tctctttagt tgtgatcaaa cggtaaacac ggtccaagaa
    16801 cttacgtgag ccttcaagac cttcttcaga ccaagcgatg gaagcgtcaa gtggtcccat
    16861 gaacatctcg taaacacgaa gagtgtcagc accgtactgt tcaacaacat catctgggtt
    16921 gacaacgttc ttaagtgatt tagacatctt agctggtgct tgttcaagct cttcaccagt
    16981 ttccacatgg aagaagctgc catcacgttt ttcaaccttg tcagtcgcta caagcgctcc
    17041 tcggctgtcg cggtagcttg ttcccaaaat catcccttgg ttaaagagtt tttggaatgg
    17101 ctctttggtt ggtacgacac cgagatcgta aagaaccttg tgccagaagc gagcgtagag
    17161 aaggtgaagc acggcatgct ctgcaccacc gacatagata tcaactggca accattgttt
    17221 gaggagttcc tcgtcagcca gtttttcggt gttgtgtgga tcgatgtaac gaagataata
    17281 ccagcttgaa cctgcccatt gtggcatggt gttagtctca cgacgacctt taacaccatc
    17341 ttcacgagtc acttccaacc agtctgtcac gttagcaagt gggctctcac cagtacctga
    17401 aggacgaata tccttagtta ctggaagaac cagtggcaac tcactctcag gaaccgctgt
    17461 tgaggtccca tcttcccagt ggatgattgg gattggctca ccccaataac gttgacggct
    17521 aaagagccag tcacggagac ggtaagtcac tttctcatta ccgacgcctt ctgcttcaag
    17581 ccattcgacc attttggcaa tagctgacgc tttatcgaga ccatctagga agcctgagtt
    17641 gatgtgaaga ccgtcttctg taaaggcagc ctcttcaaca ttaccacctt caagaacaga
    17701 gatgatgtct aggttaaatt gttttgcgaa ttcccagtca cgttcatcgt gggctggaac
    17761 agccatgata gcaccagtac cgtagctagc aaggacatag tccgcaatcc aaactggcat
    17821 ttcgttacca ttaactgggt taatagcgta gctacctgtc cagacaccag ttttttcttt
    17881 ggcaaggtct gtacgagcaa ggtctgattt gagacttgct tgacgtttgt agtcagccac
    17941 ggcttctgct tggtcagctg tcgtaatagc atcaaccaag gcatgctcag gagcaagaac
    18001 ggcgtaagtt gcaccaaaaa gggtgtcagg acgtgttgta aagacagtga agtccttatc
    18061 tgtatcctta accttgaagg ttacattggc accagttgat ttaccgatcc agttgcgttg
    18121 catgtccttg attgattctg gccagtcaac ttcttccaag tcttctagca agcgctctgc
    18181 ataggcagtg attttgagca tccattggcg catgggtttt ctgacaactg ggtagccacc
    18241 acgttctgat gtcccatcag ggagcacctc ttcgttggcg atagctgttc ccaattcttc
    18301 aacccagtta acgggaactt cagcttcgta ggctaggcct ttttcataaa gcttggtaaa
    18361 gatccactgc gtccacttgt agtagttagg gtcagttgtg ttaacttcac gatcccagtc
    18421 gtatgagaaa ccaagagcat taatctggcg tttgaagtta gcgatgtttt cagctgtaaa
    18481 ctcggctggg tcattaccag tatccatagc gtactgctca gcaggaagtc caaaggcatc
    18541 ccaacccatt gggtggagga cattgtgacc ttgggcacgt ttgaaacggc tgagaatatc
    18601 agttgctgta tagccttctg gatgaccaac gtggagacca gctccagatg ggtatgggaa
    18661 catatctagg gcataaaact taggttttga tgcgtctgtt cctgttttaa aggtgtgatt
    18721 atctgcccaa aaggcttgcc atttgggttc aatagcggtg tgatcgtaaa atgtcatgtg
    18781 aaatctccca tgtaaaaaat ctagtcttct tattatagca tgagatgaag cttttaggaa
    18841 tggtcaagac atgactagcg ccttggcttt tgagacttca gacgattagc tatttttaaa
    18901 ccctgcttta gcatcaacca tcctcacaaa aagctaataa aaaagccaga cttgctctgg
    18961 aaacagagcc aatctggaca aatagactta aaaagcaagt gcttgctcaa aatcggccaa
    19021 taagtcttcg atattttcaa caccacaaga caagcgcagc aaaccatcaa caaccccttg
    19081 ttccaaccgg gcttgtgacg ataaacaagc atgagacatc gttgctggat gtgacaaaat
    19141 ggactctact ccacctagac taacggctaa aatcggcaac tgaatacgat gggtaaagat
    19201 catcagctcc tccttagaag ccaactcaaa ggataaaaca gcaccaccat tcttagcttg
    19261 ttgcaggtgg gtatcgtgat taggatgact gtctaagccg gggtaatgta ctttaagaac
    19321 tttggggtgc ttcgctaaat agttagcgag ctgctgagca ttttttaccg cttgttccat
    19381 acggatcccc atagttttca tgccacgaag aatcagccaa gcgtcttcga ccccaacaat
    19441 tgctccaaag tttttttgaa aaagcttgag ctggttgtag atagcctcat tattggtagc
    19501 agctaaacca gctaccacat cactatgacc attgataaat ttggtcacac tttctaccac
    19561 aatatccaca cccatagcta agggttcttg atacaaactg gtcataaagg tattatcagc
    19621 cacagttagc acaccataag ctttggcgag ttgcacaagc tctgaaatat cacaaatttt
    19681 caagagcgga tttgacggtg tctctagata aatcatacgc gtattaggcc tgatacttgc
    19741 ttttactgtt gctaaatcag ccatatctac aaagcttgtt tcaatctgat aattgggtaa
    19801 aatagctgtc gcaaattgac aagtccctcc atagacctcc aatgggaaaa tcacatgatc
    19861 tccagctttt aagagcatca aaacagttga aatagcagcc ataccagatg cataagccac
    19921 cgcataagtc gctttttcta aacaggctaa cccgtcttct aaagcttcag tcgttgggtt
    19981 tgaaaagcgt gtgtacaaat gtttttgact aggacaatac agttctgaat tgtggaacgt
    20041 cgaagtctga tagatgggaa ctgaagctgc tcctgtaaac tcgtcaataa ccgtatagcc
    20101 atgtaataag gtcgtatttt ctctcatttc gtgcacctcc gcaatagcgt taactccaat
    20161 gaactctctt ttagacaatg gtcccacccc aatggttgca caaaccaaaa agctcttcaa
    20221 aaaagcgtga tctgctaacc tataagaaaa gtagtgggca ccttttaaac ggataatgaa
    20281 tttttccaac aatatcattt ttagatcgat tacgtttatt atacaacctt tagctaagtt
    20341 tgcaagccct tttatcatct ttgaccaagc tgccaacacc tctccagcaa gttaaagtat
    20401 agttaccttt ggccccatcg tctcaaaagc tcagcttatc acactgacag tcctactttg
    20461 catcgtcacc tactcaatat ggcaatatta ccatcaaaat ttcattaaaa gatcacaatt
    20521 tatttcattt aatgaaaaac agaacttgtt ttcaccatgc gccttatagt acactactaa
    20581 agtactattt atttttagga gagaaatata gtgaaaaaca aattattttt agttgccctt
    20641 gcgaccgtaa ctgtcctagg gccctcttta gcaacccctc atcaccggac cgtgcatgcg
    20701 actgaacaga cagtaactca aagaacagct actgaaacat gtacattaaa tggaaaaata
    20761 tgctatggtt atgaaaatcc cgatgaagac tacaccgata gcatggttca atctaagtct
    20821 caagatcaag gtttcttcag ttggctttgg acacaaataa caacttggtt ttcctcatta
    20881 atgagctaaa accatctcgt ggcggttttc taatcctagg tcgccacatt tcttattcag
    20941 ataaataata ataaaaacat taaaataaca cttgatttat taacaaaaag ttagtgtaat
    21001 ataatcacaa tacaaattaa aggagttatc tatgaaaaag aaattatctt tatttatgat
    21061 cgcaactgct gctgtcgtag gccttagcct tgcaacacca gaaaaccaaa ctgtttcagc
    21121 aaatgcacag acaccagctg ttcaaaactg tgaaaacggc tgttgtgacc gccctttctt
    21181 tgggtattgt ggacctttca gctggcttta ctataataca agatattttt tggggtattc
    21241 tgatacagct actaaccaat aaatttgttt ctatagtgag acaaaagccc aagcctgttt
    21301 acgcagtcct gggctttttt gctgtcctaa agtcagggtg ttgccacagc ttcaaatcca
    21361 aaaacaatta aaccgcaccc caacaattag acataggcta tgtctccaga atcctggaca
    21421 catatcacta aagcctaatg attaaggtgc agtttaaggt gtggtagcaa ggaactgttt
    21481 taaattcgtc tgcgtctaac tatacccact ggctatggag tcagcttaga gttgattatc
    21541 aagtgtcaaa tcaacttttc ccaccaatgt aaaatgagtc cccatataaa cttgacagga
    21601 agtaacaaag ggtagcttcc cccaaatcct tcattataac cctctttgta cccatcttta
    21661 taaccatctc tataatgctc atgattagag tcatcaatat ccttaggtga ttttggtact
    21721 tcagggtcag gtggggtcaa atcggtccat tcggctactt ttccatcttc tttccccttt
    21781 gttaaatctt ggttatagcc taatctccaa gggtctttat cctcctcatc tgccataaca
    21841 ggtcttgcta taagcaacat agcagtaagt agagccatca agaggtagac gaagtgtagt
    21901 ggcttgtaag attgttgttt catgataata gttatctccc ccttttatgt tatgctttgc
    21961 ttgttaaaaa gcatcttgtt agtattatag attagaagtg gcttagcttc aaggtaacta
    22021 tgtaagaaaa gaataacttt ttgattagca tatcaaaaaa cttgtctatg aaaatatctc
    22081 atagacaagc tttttgtatt tgtgtgagga gtaggcacat ggcctcaaga gataagcagc
    22141 atcaaggtgc ttgacgaacc tcttgaacca gtcctactta taagtaatcg aaccatatgg
    22201 gctcaaggtt gatcctgaga tgttgacatt gatttcttta gacagtttca catctctttc
    22261 gtcgatcact tttcgccacc attcccaagc taatccggtg cactctctag ccatgatacg
    22321 gatatttcgt gaattagctc ctagtgggat aactgtgcta aatggtgatg tcttactata
    22381 ccagttgttg tcccaacgtc gttttgtaat cacttctttt cctttgtcat cataattgat
    22441 ttcatcccaa aggatttcat attgagcaac ataggcacct tgatgagaca ggttaatttt
    22501 tccactcgtg tactcggtag atgttgtttc aacgtattca cttctgttat tgacacccgc
    22561 aattttatta tttttaagga aaacactggt gtatgaaata ggataagctg ggttttttct
    22621 actgaaggta gcattatctt tgataacgtt tctaataaca tcaaagtctt ttgtgactac
    22681 cttattgtgc tctgcagcat ctcctcctaa aacgacagct gtaaatgaac tattttctaa
    22741 aatatcagag tattttccat tagttttaac atctgttcct tttagagctg cactaaaggc
    22801 cgcttcaaca tcattacttt tagaacttgt ttctagtttg acaaaaacag ttcgaccata
    22861 agctacgtta ctcacaaaga gtggcggggc ttcattgctg acaccttttc gttgcaactc
    22921 tttaaaggtc actgatttat caaacacatc cgcaggatta ttaggaaggt ttgctgatac
    22981 ggtgtaaaaa atttgcttgt atgctgcaat catcaccttc ttttcacctt ttgaaatcga
    23041 cttgaaatca atgcctaaag taccatctaa gattttacta ttaacattta gagctgcttc
    23101 aatctgtgat ttagaatata ccattgattc agtatattgt gttctggcag gaagcgtatt
    23161 accaccagaa taattatcat gccattggtt aacaagatta tcaatagctg ttgaaacatt
    23221 ggcataggta gggtcattga cctcaaccgt tgctttgtct cccatacctg gtaaatcaat
    23281 atggattttt tgtgggtttc gcttggtgac tactgcgtct ggtttgtttt cggtaaaacc
    23341 tttattagcc agctgaaggg ctgctggata ggtcctatca gtgacagagt caatgatgga
    23401 aatatcgacc ggtgtagtgt tgatattttt tttctttctt tcaatgacaa taaatttgtc
    23461 agctttctta acgccttctt taggaacaaa gttttcaatg gtttcaccat ttttagcaag
    23521 tacttcaagc tcattataat ttagtgaata aatcttgtca ttgatttctt cagtatgatc
    23581 ttcttcgctt tttttattgt cttctgactt tttttcttct ttttctgcag attctagtgg
    23641 catttctttg ggagcaagct taatcatatc gttagagtta agcatatcat ccattttctg
    23701 acctgctttt tctgtagtta gctcactact ttctggtttt ggttgttcat ttgtcgttgt
    23761 ggtttctgta ttggcagtgt tttgtttgtt cgagtcagca ttagcagtaa caagattacc
    23821 aacgataaga gctgccgtta atagcccagc gacgcgactg tattttttaa atattttttt
    23881 attagacatg tccttcatac ctttttatca ttctaaaatg tttctattgt tctttcgacc
    23941 atatcaagca tagtatcttg atagtgagca aattctccta atttgtaatg tgccatagcc
    24001 tctctaatat gcgcatcttt taacgctttg gttatattag ctagtatgct ttgacggttt
    24061 aaataaaatg gcaagctttc gtaataattt aataacatgt tttcagcgtt tagggtttga
    24121 accgcttggt aaatgtctaa tgcttgaccg ctatttgaca tttttaataa tgcttcttcg
    24181 atgttagctt tcaattgagt atagcctttt atgaaagcag ggtaaatccc atactctaaa
    24241 ataacttctg gatcagaaat atctcccata taggagtctc ttttagtgat acgatactct
    24301 ttgtcactac ctatcaagta tttttttaaa tcattaacag ttacttcttt ttgaaacatt
    24361 ttttggtaat gttctaaacc ctttggcacc ttatacatat tgttacttcc tatcttgcat
    24421 tttcttaatt ttgaagcgac cagttacttt tttatggtca ccatttggag caatgatggt
    24481 aggatcaata atctcaaaat agcctttggc atcaatctct gctaagacag ctttagattt
    24541 tagatcttta acactaatcg atgggaaaat taattcactt tctgaatttt caatgtgttt
    24601 tcctgaccac gtttggcaac caggaatgtt gagcgaattt gctccaggag tatctccgct
    24661 agctgttcgg atatagccta gcttatcaat gttttttgtt agttcagaat cgtactcata
    24721 ttgataaacc ccatcgctat attttccgct atcgacacct tttatatttt caatttggtc
    24781 agctgatttt aacttacctt gatcagtaaa gagcaatgcc atatcttcag caaaacttgt
    24841 cacaaaaaga ccgttttctt gtcgaccaat cgtcgacttt cttttagcat catcaaaagc
    24901 taacatcaaa tcttttttgc ttgtaacgtg ggaagctccg ctttctttgt agacttgttt
    24961 tagtttttca acaaactctt ttttgtagtg gtatttgcgg ctaacgtaca tacggtaata
    25021 ctcagcacgt gacgcaacag cagacatctg aacagcttta tcagcatact tgtcggcggt
    25081 ttcaataaac tcatctgctt gtttatctgt tacccattta tctttaattt ctttaaactt
    25141 tttttcaaaa atatcgcgtt ccatattgcc aaaagtgacc tctgacaagg ctaaaatatc
    25201 cttgttttga ccctgatgga cctctgttac ctcaatatca atacgatcaa catctaattt
    25261 tttatcaatc tcaatgtgat gcggtttttt agtgtaggtg tcgcctaatt caattttttg
    25321 aaagaggacc aatttattcc cgttatagta tttaacatca gcctttgcaa ttctattttt
    25381 cttgtagtaa ttctccttgc tagatgtatc tccattaaca attaaaattc tcccaatatg
    25441 catcggggac gcaaacttgt aagaaagtac ctcaccaata ccaccgccag gtgaattttc
    25501 ctcccaaaca gtactcattg agccgtctaa tgtgtgcatg acatgtttgt cttctttaga
    25561 ggaagtggcg ttagcttcca taactttggt catttcatat ttgacatcgc tttttttacc
    25621 ttctttgcca ctaacagcgt acgttgtgtt attagctaat aaactgctac ccattgctcc
    25681 agccaaagca atagcaacac ttgtcttcgc gacaatatga gctaatgtta cttttttgtt
    25741 tctcatgtaa accaccttat attattttta agtaaactat acattaacaa atagtttttg
    25801 tcaatgcgat ttattaacat cgttttagga ttttctataa aaaaaatgaa caaaaaacaa
    25861 gtaggcaact gttacagttt tcaaggtaat atgtgcatct tatcatcaca gaaccttcac
    25921 atctgttcta tttaaaccag attaaaagta ctagttaagt atttgatagt agcagcgtta
    25981 tcagtaatag atctgttaat tatctctgat tacaatgatg ttaacaatag tcataccttt
    26041 atttgtacac acgcttcact tccaactaaa aaaggtctga tggtaatact tataccatca
    26101 gacctttgag agcctatagt tctgcgattt ggtaaagttc aacttcggct actgtttctg
    26161 atccaaacat gttcaacatc agtttcacct tgttattttc aatctcaacc acacgacctt
    26221 cttgtcccat aaaggcaccg tcaatgattt gaaccacatc gccctctttg atgttggtat
    26281 caaagacatc aatggtttgc cccatagata ataggatggc acggatttct tcttcaagta
    26341 gtggcgttgg tttagaacgg ttcccgtgtg aacccacgaa cccagtaacg tttggcgtgt
    26401 tacgcaccac gaaccaagct tcatctgtca tgaccatttc taccaataca taccctggga
    26461 agcggttttc ttcgatttct ttggtttgcc catttttttc aacgttaacc gtttgtgtcg
    26521 gaatttcgac gcgcaaaata ttgtccaaca tgttataggt ttgggcacgt tgcaagaggt
    26581 tttcttttac tttgttttcg tagcctgagt aagtttggag gacgaaccag cccttatcaa
    26641 atgaatctag catgatgttt cctttcatta taaaaaagcc ctttttttgg cttttgcgct
    26701 gttttctatc accttcatta taataaaaga cagggctgct gtcaacgtat ctgtggagct
    26761 acttgacacc tttattaaaa agtccaaagt cggttcgtga cgactctgga cggtattgta
    26821 cagttttagt tttcaggaac tgtgatggtt ccttcgataa tcgctttttt agcagcctca
    26881 atagcttttt tagtgtcttg tgtcagagca tccgttgtaa ggctaacacc accttctttt
    26941 aaaccaaaag tggttatttg accacctggg aattggcctt ctgaggtttt tacggctact
    27001 tttactaaag cttttccgac ttccttgata cttgaggtca aaacaaaatt agctgacttg
    27061 ccatcttttg tggtgtattt tccatcttca ctttggtcac ggtcaacacc aataacccaa
    27121 accttatctt cttctttacg tttttcgttg atagacttag cttcgctaaa gacacccgct
    27181 cctgtgcctc ctgctgcatg ataaataaca tctgcgcctt cagcgtattg agcagctgca
    27241 atcgtcttgc ctttagcagc atctgcaaaa gagcctgcat aagcaactct tactttgatg
    27301 gtatcatcta ctgatttcac accagcttca aaaccttttt caaagcgctt gacaacatct
    27361 ccttccatac cacctacaaa accaacttgc ttggtttttg tcgttttagc tgctgcaaca
    27421 ccggctaggt atgccgcttc atggtctgaa aaggtgatac ttgcaacatt tttttgacct
    27481 ttaatcacat catccacaat tgcaaaatgg ttgtcaggat tgtttgcggc tactttttct
    27541 acagcgtcat gtaatggaaa tccaatccca aaaacaagat tataaccatt ggttactgct
    27601 gactcaaggt ttgtggtaaa ctctgattca ttggctgatt ggaaataatc atagcctttt
    27661 cctttttcaa gtttattttc ttttccccaa gcttgcaagc cttcccaggc tgactggtta
    27721 aatgacttgt catcaatacc cgtctgatta gtaatcatag cgatttttaa tgaattgtca
    27781 gttgtttgtt tagcggagtt attggtacag cctcctaatg tgaatagggc agtcgaaaca
    27841 agaccaagtg acattacttt tttgttcatg tgaaaatgaa cctcctaaat gtttaatcct
    27901 aaagtgatgt gtcattgtta acgttctact tatgctctag aacgaaaagt ttagtatatc
    27961 aaaaaaatca gttttatcct actatttttg ttgaaaaatc tctttttcac caaaatgacc
    28021 gaacgataaa gtgagatcaa ctggtaaatc ccattatctc ctcaaaaatc acctcttaag
    28081 gagataagtc aacgacaaaa ctcaagctac tagtaatagc atgactaact ataccatcca
    28141 acaagcggta aaaagagctg gaaacgctat tcaactcttt gtcatactag acaccttaga
    28201 tagatgccca gaccgactca agaatattgg tctgttcacg tcctggacca actgagaagg
    28261 ttgaaatgcg aacgccaacc aattctccaa cacgacggac atagttgcgg gcattttcag
    28321 gcagctcatc aaggctacga acacccgtga tgtcctcttg ccagcctggt aattcttcat
    28381 agattggttt gcaacgtttg agttgttcaa gacttgctgg gtagtgatca atacgttcac
    28441 catctaaatc gtaagccaca caaatcttaa ccgtatcaag tcctgaaaga acgtcaatgg
    28501 aattgaggga aaggttagta atccctgaca cacgacgact atggcgcata acaactgagt
    28561 caaaccaacc tacacgacgt ggacgacctg ttgtcgtacc gtactcatga ccaacttcac
    28621 ggatacgttc acccacttca tcaaagagtt ctgtagggaa tggcccatca ccgacacggc
    28681 ttgtgtaggc tttacagacg ccaactactt tgttgatttt acttgggcca acaccagaac
    28741 caatggttac accaccagca actgggtttg aagacgttac aaatgggtaa gttccttggt
    28801 caatatcaag cataacccct tgtgcacctt caaaaagaac acgtttaccg gcatcaagtg
    28861 catcatttaa aattacagaa gtatctgtca catattgctt gatttcttga ccgtaagcat
    28921 agtattcttc aaaaatagca tcaaaatcaa gaggtgtact gtcatacatt ttttcaaata
    28981 aacggttttt ctcagctaaa ttaatgcgta ggcgctctgc aaagatatcc ttatccagta
    29041 aatctgcgat acggatacca actcgagcag ctttatccat ataagctgga ccaatccctt
    29101 taatagttgt tccgatttta ttgtcacctt ttgcatcttc ttgcagttga tccagctgga
    29161 tatgataagg taaaatgaca tgagctcggt ctgaaatgcg aaggttatct gtcgtcactc
    29221 cttcatcatg caggtacgcc aactctttga ccaaagattt ggggttgacc acaacaccat
    29281 taccaataac ggaaattttt tgcgggaaga aaattcctga tgggatcaag tgaagtttaa
    29341 acttcttacc atcaatcacg atcgtatgac cagcattatc accaccttga tagcgagcaa
    29401 ttacttctgc atccgctgac aagaaatcag tgattttacc tttaccttcg tcaccccact
    29461 gggtaccaac aacaactaca gatgtcatat cattgtccta actttctgaa acacttattc
    29521 tcaataaaaa tcataggcaa gctaaccact gcttaaaaac caaaaagaag gtcagatctg
    29581 taagatcagc aatgtagctc ttgattttta aagaaaacag gcaggaatct cacctgctag
    29641 catatatctt acaacttatt atagcaaaaa atgatttttt ctgctagatt tcttagcatt
    29701 attaaggaaa aagagaaact ctttttttaa ccatgataaa caatcctaaa aaaacgaaca
    29761 ttataagaga aaagctttta acctcgtttc tcctaagctt tagcagggtt aaacgattct
    29821 cttaaaacat tagctctttt ctttcagaaa tagcggtttt aaggtaaaat aatagtaagt
    29881 tacctctatg agatagccag taaaaacata tcgaggaaat atcacatgat tagaaagtat
    29941 gaccgcacga gcacaaaaaa gaaatcacta aactggattt ggctaatcat cgcttttttt
    30001 atgatttcaa gctttatagg tggctcttct tttactgagt cacttctaga cattttgcct
    30061 gccatagcca ttggtggtac aggttatgct atttttcgtg ttagatctca tcaaaagcgg
    30121 ctagcaaagg ccaaggttgc caaacaatta gaagatctaa aagcaaaaat tcagctagct
    30181 gatcgtaaag ttcggctgtt agatacttat ttggcagacc atgatgactt ccaatataac
    30241 gtactagctc agcaattatt accacaactt agtgacatca aagcaaaagc tattacgtta
    30301 aaagaccagt tagatcccaa aatttatcgt cgtatcacca aaaaagccaa tgacgttgaa
    30361 agtgatatta cccttcaact cgaaacactg cagattgcca caactcttaa ccctcagcct
    30421 ttgaaaaccc catctcctaa tcttattaac aaagcacctg agctcaaacc gtattatgat
    30481 aatattcaga cagatcatca agctatcctt gctaaaatcc aaggagccga caatcaagaa
    30541 gaattgcttg cgctgcatga agctaacatg aggaggtttg aggatatctt aacaggctac
    30601 ttaaaaatca aagaagagcc taaaaattac tataacgctg ctgctcgttt agaacaagcc
    30661 aaacaagcta tccaacaatt tgatgaaaat cttgacgaaa cccttcgtcg actcaatgaa
    30721 agtgatctta aagattttga tattagcctt cgaatcatgc aaggtgctac tcaaagacga
    30781 acaacgcatc atcaaaaaga ctaaaggagt ccctttatgg cagattttaa ttttgacatt
    30841 gaccaaattg ctgacaatgc tgttgtcaaa accgataaaa ccaccgatat tatctcagac
    30901 ttaccaactg acacaaatgg ccaaatctct ttttttgaga aactaagtgc tgaccagcag
    30961 acagccatta ctgccagagc cccggcattg gtagatacct ttttggcaga ccaaaatgcg
    31021 ctacttgatt ttggtcagtc tgctgttgaa ggggtcaatg caacggtcaa tcatatcctg
    31081 gccgaacaaa agaagttaca gattcctcag gttgatgatc ttttaaaatc aaccaatcgt
    31141 gaactcaatg gttttatcgc taaatacaag gatgccacac ctgtggacct tgataaaaag
    31201 ccaaactttc ttcaaaaact ctttaaacaa agccgtgata ccctgcaaga gttttatttt
    31261 gattctcaaa acattgagca aaaaatggat agtatggctg cagcggttgt caagcaagaa
    31321 gataccttag ctcgcaatat tgtctcagca gaattgttaa ttgaagataa tactaagtcc
    31381 attgaacatt tggtaggcgt cattgctttt atcgaagcta gtcaaaaaga agctagtcag
    31441 cgcgctgcgg ctttacaaaa agacctaaaa accaaagaca gtgctacacc agactatcaa
    31501 ataaaagctg atcttttggc aagaactacc gaagtcatca acaccctcga acaacaacac
    31561 accgaatact tgagtcgcct ctatgttgct tgggcgacaa ctccgcaaat gcgtaatcta
    31621 gtcaaggtct cttctgacat gcgtcaaaaa ctaggcatgt tacgccgcaa taccattcca
    31681 acgatgaaac tatctattgc tcagttaggc atgatgcaac aatcggttaa atctggaatg
    31741 actgctgatg ccattattaa tgctaataat gctgcccttc agatgctagc agaaacaagt
    31801 aaagaagcca tcccagcatt ggaacaatca gcacaaaacc ctactttgtc tatgaaatct
    31861 gtgacaagtc tggcagaaag tttagtagca caaaataatg ggatcattgc ggcgattgat
    31921 catggacgca aagaacgagc acaactagaa agtgctatta tcaggtctgc cgaaaccatt
    31981 aacgattctg tcaaactacg tgaccaaaat attgtgcaag cacttcttag tgaaggcaag
    32041 gaaactcaaa aaacaattga taaaacaact cgcgcataag ctaaacatca cctgtcacgc
    32101 tacttaaaaa gcaagccatc agttaggtta atccctttga tggcttgctt ttttactact
    32161 taacgaataa tcgccttgtt tgatataaca cttatctttt atgatgttat tttcataata
    32221 cgaacaaggc tagcacgctc ggcctcttct aatttcaact caatgtaatg aatcgtctct
    32281 ttcagttgcg ggataataga atactctaag ccattgacgc gacgtctagt cttttcaatg
    32341 tcatcagcca ttagttgaca agttttttca acttcagcta accgtaagag cttttctaat
    32401 agttcttttg tcttttggat agtattgtcc atctcactat ttgagctgag gtaactataa
    32461 gcaaactcac cttgttcttg ctctcttgcc gtattagact ggacatggaa tttaggcaca
    32521 ttgacactca tgatattttc aatatcaatc cataaggtca cttcatggac tggaacagca
    32581 aagagttctt ctaccattag actattttcg gatgcttttg ccaagacaaa ctccttcata
    32641 ttggcagcaa gttctttttc gatagtttga cgaagctcat tgttttcacg aattaaatca
    32701 acgaagcggc gcatcaactc atcccgcttg tcctttaata atttatgacc tcttgtagct
    32761 gtcttcaagc gatttttcaa gttactaagt tccatgcgtg ttggtttaac atttaatcgt
    32821 gccattgata taactccttt cgtcaaggac ttgaaattgc atggtcaact caatcatttg
    32881 caacaaaaac ctttgtcatc gtggtatctg ctttaggcaa ataacgatct aacatatcat
    32941 ctttaatgcg ttttaattcg gtacgtggca aaatcgacaa caattcccaa cccaagtcaa
    33001 gactttcttc aatgctacgg ttggtgtaaa atccttggtt aatgtattct tcttcaaacc
    33061 ggttggtaaa ggccacatat agtttatccg tttcagaaag ggctgattca ccgagcacaa
    33121 cagccaattc cttagcttgt tttccttggg cataggctgc aaagagctga ttcattgtgg
    33181 cagcatggtc ttgtcgagtc ttaccttcac ctgagccttt atcttttagg cgagatagcg
    33241 atggcaagac attaataggc ggtctaaaac catttttata tagttcttgc gacaaaataa
    33301 tctgaccttc ggtaatataa cctgtcaaat cggggatagg gtgggtaatg tcatcttctg
    33361 gcatggttaa aataggaatt tgagtcactg accctttttt cccgatcaag cgaccagccc
    33421 gttcatataa ggtggagaga ttagtataga gatagccagg ataacctcgt ctgcctggaa
    33481 cttctctgcg agcggctgat acttctcgta aggcttcaca ataatttgtc atatctgtca
    33541 tgatgactaa aacatgcata cctttttcat aagccaagta ttcggctgtt gtcagagcta
    33601 tacgtggtgt tgcaatgcgt tcaatagcag ggtcattagc caaattgata aataaaacag
    33661 atcgatcaat agcacccgtt tcacgcaagt cattcataaa gaattctgcc tcttcaaaag
    33721 taatacccat agctgcaaac acaaccgcaa agttatcatc agagtttaga acagttgcct
    33781 gacgagcaat ctgtgcggcc aattcattat gaggtaaccc tgagcccgaa aaaactggta
    33841 acttttgacc acgaacgagg gtattgagat gatcaatagc tgagatacct gtctggataa
    33901 attcgtctgg gtaatcacga gcgacaggat tgatcgcttg accatcgata tcgaggtatt
    33961 tttcgggaat aagttctgga ccgccgtcta tgggctgccc cattccatca aagatgcgcc
    34021 ctaccatatc ttctgatacg gctaattcca aaggatgccc tgtaaatcga accttggttt
    34081 tggctaggtt gatgccagtt gatccttcaa atagctgtac catagcctta tcaccttgga
    34141 cttctaagac ttgaccttta cgcctttctc cattatgcaa agtaatatct accaattcgt
    34201 tgtagtgcac tcctgcaact tgatcaacaa tcatcaaagg gccaaccact tcgctaaccg
    34261 tccgatattc tttgagaacg ctcatctaaa ttcctccctt tgctaaaacg tggtgaatct
    34321 ctttggtaac cttctgagta agccctttaa tctgctctaa gttttcttct gggataaatt
    34381 tgctgcgtgc gatgcgatcg cgtacctgag cagtgccttc cataatctca ttaaaataag
    34441 ctcccaaaga aagggctttg ctggcttcct cattaaaggt caaaatattg gttagcatgg
    34501 cctcttgttt cggaaaggaa gtaaaggtat ccaccgaatc aaaggcattt tgctggagat
    34561 aatcctcccg aatttgccgg gcaacagcca tggtcaaacg atcttgttca gacagtgaat
    34621 caagccccac caagcgtaca atttcttcta gactggcttc acgctgcaaa atagccatgg
    34681 cacgagttac cttgttggac caattagatt gctgtttacg gtcaatatag cttcctacat
    34741 catcttgata caatgaataa gacgtcagcc agttaatcgc tgggaagtga cgccgttgcg
    34801 caagaggcgc gtcgagcccc cagaaaactt tgacaatccg aagggtgttt tgagtgacag
    34861 gctctgaaat atcccctcca ggaggagaaa ccgcgccgat ggctgtaatg gttccctcac
    34921 gttcttgact tcccaaggtc cgaacacgac cagcccgttc ataatattcg gcaatgcgac
    34981 tccctaagta agccgggtag ccttcatcac caggcatttc ttgtaggcgt cctgacatct
    35041 cgcgcagagc ttctgcccaa cgtgatgtcg agtctgccat gatagccaca gaatagccca
    35101 tatcacggaa atattcggca atggtaatgc ctgtgtaaat cgacgcttca cgcgctgcta
    35161 ctggcatatt agaggtgttt gcaattaaca ccgtgcgctc cataatggac tggcctgtat
    35221 ttgggtcaat taactctgga aactcattca aaacgtcggt catctcgttg ccgcgttccc
    35281 cacaaccgac ataaataaca atatcaacgt tggcaaattt agctatttga tgctgcacaa
    35341 ctgtttttcc tgccccaaat ggtccaggaa cggcagcggc accacctttt gtaacaggga
    35401 aaaaggtgtc aataacccgt tgacctgtaa ccaaaggctc gactgggata aacttttgag
    35461 caacagggcg actttgacga actggccaag tctgcatgag gctaccttgg taaatggaac
    35521 cgtcttcctg cttaatttca taaactgtat ctgttactgt gaagtcccct gcatgaatag
    35581 ccaccaaggt ccctgaaact ttataaggaa ccatgatacg atgctcaatg acagctgttt
    35641 cttgcacagt tcctaaaata tcacctgcaa ctacttcttg accaacactt agcttgggaa
    35701 taaatgccca cttagccttt cgatcaagac ttgggatagc cacaccacgg attaaaaagt
    35761 cgctgtccgt tgctttttga aaacgatcaa gcggtcgctg aataccgtca aacatttctg
    35821 aaatcaggcc tgggcctaac tcgaccgaca aaggacaacc agtagtcact actggttctc
    35881 ctggaccgat ccctgatgtt tcctcataaa cctgaataga cgcttgatcg cggcgcattt
    35941 caataatttc tccgactaag ccaagatgtc ccacacgaca aatatcttga atattagctt
    36001 cttgcatccc agaagccaca acaagaggtc ccgaaacggt tattattttt ccttggttca
    36061 cctttttcct cctttatttt ttccaaatca tactaactaa tctatactgt caaggtttaa
    36121 tgtgactatt ttgaatagtc agcaaactat cctatgcgtt cagctgctaa cttcaccaat
    36181 tttcctgtcc ttgcatttca tcagttagct actcataagc ctcaaacaga gtataagtcc
    36241 tctttgccta acgtcttagt gttataaaat attttgaccg acagcctttt caaccatggc
    36301 ttgtatgcgt gacaggccta tcccttgcgc tccttgatga gttggtaatg gtatgactgc
    36361 tggtagaact tgattatcat agtgagtgag ggcttctgga atagctgcag caatatcttc
    36421 tgtgatataa ataataccaa agtcttccat tgctagttga cgcaactggt taatagcgtc
    36481 ttgtggtttt attactggaa aagtttgaaa cccaatcatc tgaaaaggta aaataacatc
    36541 tctattacca attaccccga ctttatacaa tgttttggtc atgctattgg tctcatcctt
    36601 tctatgacac gttctttggg taaatcatta gctaaagcag ccgctaaaag ccgtaggttt
    36661 tttacttcaa acgatttagc gagcaaaaag cgagcaagca cataaggccc atcgacttga
    36721 tatttggcct tcgcaaataa atggtaaagg cattcatcaa caaggtattc taactcagtc
    36781 gtttgaagag tgccttggcg aagtttctct gaataaggtt ttagggctgt catatagcta
    36841 tcaggtgtta cattttcaaa ccacgtcatc agatccttat catcttcaag tgtgataaat
    36901 gttttacttg gtctacttgc ttcatcagat aataactgca tcatgaaact tattggttta
    36961 ttttgcgatt tggcccgtct gacggtaatc agattataca aatcaatcac aataagaaca
    37021 gcttgttgga aaacagggtc ctctaatctt tgtgctattt gtttcaacgc cttaaaataa
    37081 gctaagtcag taccaatttc taagacgcgt atgtcttgat aatcttgata ttcggcccaa
    37141 atggactgga tttctgttac cacctctttt ggaaactcat cagaagtcat cgtcctaatc
    37201 aaatgttcca aagccaccaa aggcttgtca ccaattggta gtaataagtg actcagatct
    37261 gcttgactag ctttagcttt taacaacact ttgacattat gataggtgta acgcaaggta
    37321 aataattgta ctatgtcagg ttgaggggtt tctgcaaaag cccagcgata ggtcttggtt
    37381 agctcagcca ttaagataga ttctagccga tccaaatcgt tgagatcgtc aacagttagg
    37441 tgatagactg actggtgcaa cagtcgagct aaggttgttg tattgggagc ctgcaatagc
    37501 ttatcaaatt gctctttagt caataactct ttttctttga cactgatagt agtgtttaat
    37561 tctagaaatg ttggcatcgc tagtcaaacc tcctatatct ctgaaaaaag catatcaatg
    37621 atgcgggagc tttcttcttt aagaactgat tctaaaaggt aacggtataa ataattgtca
    37681 tcgacttggt ctaaactgac taaaaatcct gcttcctgag gaattagctc ttgattatag
    37741 cttaattgag gaaatgctaa tctcagctca gcacaatcat aagaactgaa cttttgccct
    37801 gttttttcgc caaaagtaac ttgcaatggc tgttctggat atttagacaa gacttgcttc
    37861 aaaaaagcca attcttcttc cttagaaaag ttcgtcatct tctccaaaga agcttcaaat
    37921 agctccttta tactgtcttg ttttaatgct agtagagctt gtctttcttg gtttttgagt
    37981 tgctgctgcg caacctgaaa ttgctgttca aaagctttta actctttttg acgctttgct
    38041 tttaaatcgt gtagtccttg ctgttgacgc tctttaaagt cagtatcaag actatctgtc
    38101 gctatcttta ggcactgttg accttcttga tgtgcttttt caagaacgtt ttgtcttaac
    38161 tgtgttatat cattcaccta atttccccct tttgatagtg ttagtggtgt caccgttttt
    38221 taaaatctag ataaggaccg ttaccttatc caattttatt taagagaata aaggagacga
    38281 caaaggcaag aatagcatag gtttcaacca tagctgctaa aatgacaccc ttcataaaat
    38341 ctttagggcg cttagccaag atttgcatac cagctacaga aacattgcct tggtgcttgg
    38401 ccgaaaaata accaacaata gcaattggaa gagataccaa aaagtaagct aatccttggt
    38461 taactgaaag ttctggtgtc agtttcatcc aaattaaaat accaatagca aagccgtaga
    38521 ttccttgact accgggtaac agttgcaaga taagcgcaga cgtaaatttt tcgggttctt
    38581 cttttaagag cgcagctgcc gcttgaccac ctttaccgac accataagct gagcccatgc
    38641 cactaagagc tacggctaaa acaattccta aggctgcgaa gaaaacgcca ccatgtgctg
    38701 taaaataatg tgctaaatgt tccatgttaa ttgtcctcca aatctgtttc ttcattgaca
    38761 ttgacataat tatcagctaa ctttaaagga ttgaaagctt ttcctccacc ttcataaaat
    38821 tttccaaaaa actctacgaa aataagacga gcaccatgca catatcctga aagcattgat
    38881 aagaaaatat tgatcgcatg caaaagaata aaaataaata tacctactgt aaagcgcgtg
    38941 actggtggaa aaatcccaac aatcatgtta aaagccgctc caatactagc tccagaaagc
    39001 cctaatgcca ttagacgagt aaagctaacc aaatcactta agtaagagct aatgccatat
    39061 aaattatata atccactacc tagacctaaa aggcttttgc tttttagtaa agaaacaacc
    39121 aaaatcccaa aggcattgcc caatgcaagc cacttaccaa taaccgataa gtaagcaagg
    39181 ccagatacat tcttaccaag aataaataac agcaggccta ataaaataaa agtccaagct
    39241 agacttgacg tataggccgt agcatatgct ttcatcctta cttgttgcca tgctcctaac
    39301 aaaagcccaa atataagtgt aacaaaccca aatagcaaag aaacaaccaa aatagtaatc
    39361 acatccgttt tagttgataa taatgccaca ggtaagtcaa aaccaaagaa agaaccgtaa
    39421 ataagccccc atagggctac tgaaatagct aaaatattaa agaaggtcac taaccgttta
    39481 ctggtttttt ggagattaaa aaagaccaat gcagctagtg tcacagcata tagcaacaaa
    39541 ccatagccca aatcagctac catcatgcca aaaaaagtaa ggtataaagg agctaaaaaa
    39601 ggtgtcggat ctttttcttg atattttggc aaagcgtaca tttctgtaac caattcaaac
    39661 ggtgcaatgt agcggtgatt acgtaactta atgggaacat cttcccaatc gtctggcgtg
    39721 acatcgtaac tatccagata aaacatatca cctagtgtct tagtcattag cccttttaat
    39781 tggttaaccg aatcagcttc tatccaccct tctaaggcta ttagatgtct tgtaccgagt
    39841 aattgctttt tagtttgctg ccgttgatac tgactaagga catagtctat ttcaacctgt
    39901 aactgtgcca gtatcttttg agactgccta agctctttta gtagactatc tttttcagct
    39961 agccaattcg ttagtaactc tttgtttata cgaagttgtt ctgatggcag tagctgttct
    40021 ttatataata agggtttaaa ctgatatttc tgtaaatgaa tcgtatcttg tgcttgccaa
    40081 aataagacaa ggccgtactc aaattctgta tggtatactt cctcaataaa aagacctttg
    40141 tgcttcttta actgatgata aaaatgatca tttgctgtac taggaatcgt tccaactctt
    40201 gccgacaaaa aatgaaattg cgctaagtcc tgaggcaaaa cagtcaatga acgccacttt
    40261 tctaactcct gacagtattc tgttagctgg tctattttgt tttgcagctg ctctagtcgc
    40321 tctatctttt gtgacatcat tttcaaagcc gtttgagctg cttgttgtcg atggcgttct
    40381 tcgaactgtt taaacgaaag agatggcgtt ttttgtctca aggctgttaa ctttcctatt
    40441 ggtggtaaaa acgctgataa gctagcaagg ccgttttcta actcttgttg gctttgtaaa
    40501 aggtattgta aagcttcatc atctagtaga ggtttttgat gcgtcagatc gtattggacg
    40561 atttgtggca acttgacgtt gcctttgtta aaagcatctt gccaatgttt tagttgcttc
    40621 atgtcacgaa cttcaactaa ttgagattgt tgaagtgttt ttaaaacaag atcaagataa
    40681 tctttttcaa aaaccattgc cagctttttc atttgactaa tggccatatg tctccaccac
    40741 cttatccact aactccctaa caacggttag cttatgctct tctaaaatgg catgaagagc
    40801 tagctgttgc gtcgctaacc tcttttttga agctttttgt tcttgacgat tagcttcaaa
    40861 aaatacctca cgtttagctt ctaatagtag ctgagtttct tgttcgtact caagaaacag
    40921 ctgctttaac tcttcttctt ttttgtcagc tagagctttt ttcttagcat cgtaactgtc
    40981 ataaattgtt ctagcctctt gttcgatact attcattagt gacaataggg tattcatcac
    41041 atatcaactc cttatcttta tctattgcta attttttgac tcactaggta cttaaaaaca
    41101 aagctacaag aaaggctact tttgggggtt aatcaaccag cgactataag ctagagctaa
    41161 atctctaacc tatctactaa cagctttttt gagataggat aattgcttga ttaagcgaac
    41221 agcatcttta agttaagcgc tttcaattct atccataaaa acaatggctt agttcagaaa
    41281 aaggttagct aaaaacctgt caaagcagta agatgacaca gaactctaaa gctttgtatt
    41341 gctgtctttc gtgtgttatc ttatacttct ttaggcattt agtaaccttg atctagttga
    41401 cggtaaggaa cctttaccag ccaatagcca agccaatgtg ataacagtat aactgctatc
    41461 ttgttaaaag tcctgtcaaa aagatgttta ttagtttctc gcttgtaatt cttgttttgt
    41521 tactaaacgg taatttttaa agacagaacc tccaatataa cccacaatta agctgataat
    41581 aatacatcca agggctgtta tcaacacttt agcgacagga ttataggcaa acatcaccgc
    41641 aaaaccggca atcggagtag ctgtccctgg cgtatcatta accaatttca ttagggcgat
    41701 caaaacacca catgcagcac caccaacaaa attagtcaca taaatcggaa tgggattggc
    41761 tgacgtcaca tctgcctgcg ttagtggttc aatagcaaaa gcaatattgt cttttctttc
    41821 acccaatttt aatcggtaaa aaagaacacc attcataaaa gaagagccaa agacagataa
    41881 ggcacctata gccatcggaa tacctgtcag accaagcatg gctgtcaaag ccattgatga
    41941 cagcggagct gttgctacaa caacaatcgt accgcctagt atcattccca tgataatagg
    42001 gttgctatta gcacttgagg tcaggatgtc tccaatagtc aataaagtac tattgatcac
    42061 tggcgtaatt aactgcgcca agaaacgagt taatggtgca ccgacaataa taatcgagat
    42121 taaatcaagc ccaccaggaa tatttttttc catccacttg attaaaaaag ataccacata
    42181 cccagccaca aaacctggga taatacctgt tcctgaaact gacaaaccaa tcaaaacggc
    42241 ataacctgga gacacaccaa ttgcaatggc aaccaagata gcagcagcta cccctgataa
    42301 tgagccattt gctccgccta cttcacttag aaactgaaag cctaaaacct taccaaaaaa
    42361 agaatcttga aaggcttcaa ctaaaaaaga ggcacaagct gccgaagcca aagctcccat
    42421 tgccttggca ccatgaggag ccttataatt aaacaagcta aaaatagcta aaacaagaat
    42481 caaaagactt gttccaataa taatatccat aatctattcc accaatctat ctcattacat
    42541 aagacactat aactgcttca ctctggcaac agcttcgact tcaatcaaag cttgcaaagg
    42601 aagcgccgac acttgaaccg ctgtccgaac agggtagggc tcttcaaaca aatcagtcat
    42661 gacatgattt aatatttcca cattggtcac atctgttaaa tacacattta gcttatagat
    42721 atgattcaag tccaactttt gctctgccaa aatagattgt aaattaacaa aaacctggcg
    42781 acactgtgcc tcaaaaccat ctgacaattg acctgtcact ggattaaggg gtaattggcc
    42841 tgcggtgtat agaaaatgtc cttcaatcgt ataagttgaa taaggaccca ttggttctgg
    42901 gtagctcttc atatacgaac ctcctcattg ataatatagt taaattttac aggaaaccgc
    42961 attcacagtc aataataaat tctctttttg ataaaaaatt attattaagg tgattggcaa
    43021 ttgtttttta gtctaaaatg tattactata tttgtaaata agaagataga tataggaagt
    43081 ttgacatgga taaagaaacg ctaaactact ggaaaacggt tatcacattt cttcacgatg
    43141 tcttaggtga taactatgag attattttac atgtgattga taaaaatgat atctatattg
    43201 gagaactcgt taatagccat atcagtggac ggtctaaaca gtctcctctc accacctttg
    43261 ctcttgattt gattaccaat aaagtctata aggaaaaaga ttttgtgacc aattacaaag
    43321 caatcgttag tcctcagcac aaagaagttc ggggatctac tttttttatt aaagataaaa
    43381 agggtaatct cgagggaatg ctatgtatta acttagatat ttcagcctat caaggagtag
    43441 ctagggacct cttaaaactt gtcaatctca atttagaaca tttcatccca actgctaaag
    43501 aacctaaaac agtcacaccc cagccagaag aagctgttga aattttaacc tctaacatcc
    43561 aagatattat cggtcaaatt attgatccct cgttactgag acacaatgta catcttagcc
    43621 aagatgtcaa aatagacatt gttgccaagc tttatgaaaa aggagtattt caactaaaag
    43681 gagccgtctc aaaagtcgct gatattctat gtatttccga accaagtgtt taccgctacc
    43741 ttaaaaaaat tgaagccgat caataaccaa atcaccataa aacgccagtt aaaagtattt
    43801 cagataagca tcacaatctc tgatataccg atgactgacg tttttttact caatatgcct
    43861 ttatggcaag aaaaggctac tagtcattaa ccttcagcta tgcttagagg tacacctgtc
    43921 gcagcttgaa cctcatcaaa agtaaaccct tcactgattt caattacttg gataccatct
    43981 ggcgttactt taaacacacc catttctgtg ataataaggt caaccacacc ttttgctgtt
    44041 aaaggtaagg tacattcttt taggagctta tgctttcctt tattggtatg ctccatagct
    44101 acgatgactt ttttagcacc aactaataaa tccatcgctc ctcccatacc aggaaccatt
    44161 ttgcctggaa tcaggtaatt ggcgatatct ccattttctg caatttctaa agcacccaag
    44221 acagtcaagt caacatgacc accacgtata atgccaaaag aatctgcact attaaagaaa
    44281 gcggctcctg gataaaccgt cacaggctgt cctcctgcat taacgatagt cgaattcgga
    44341 tcatctgact taggacctag tccaataaac ccattttcag attgaaaata cactgtcatt
    44401 tcttcaggca caaaatttgc tactttggtt ggtagaccaa tacctaaatt taccaaagta
    44461 ccatcttcta attctttggc cacacgcttt gcaatacgat tttgaatctc ttctttactt
    44521 aatgcaaccg ccataactat actccttctt taacaatgta atctacaaaa atgtgtggtg
    44581 tatgaacgca ttctggttgt atggtgccga ctggtactat ttctcgcacc tgaacaattg
    44641 ttgtttttgc acaagctgcc atcaattgat taaaattatt ttcagaacca ctatactgta
    44701 aatttcccat ttcatcagct ttattagcaa atatcaaggt gacatctgct tcaaatgggt
    44761 attctaagag ataggttttt cccttgatgg tttttgtttc cttgccttct gccactaagg
    44821 ttcctacccc tgttggcgtg taaaagccac caatgccata agctccgatg cgaatttttt
    44881 cggcgaaggt tccttgagga atgagctcaa tcgtcgtttc accggcagtc atttggcgcc
    44941 cagcttcttt atttaatcca atatgtgttg cataaatggt tttgaattga tgattagcca
    45001 ccatttttcc aacaccgcga tcaacaaaac cagcatcatt acagatcaag gttaaatctt
    45061 ttgtgccttt gtcaaccagt gcatcaatta acgcttctgg tgttccatta gccataaaac
    45121 caccgaccat aatcgtgtca ccatctttaa tatgactgat agcttctgct attgctattc
    45181 ttttattctc tttcatacgg ttaccttcta tcttgttacg atgatacttt gaccttggcc
    45241 accaccaata caaagcgttg ctaagccatg tctcacatca cgcttagcca tttctgctaa
    45301 taaggtgact aaaatacgag cacctgatgc tccaatcggg tgacccaaag caatagctcc
    45361 tccattgaca ttaacttttt cattgtcaaa accaaggtct cgtgaaaccg ctaaagcctg
    45421 agcagcaaaa gcttcgtttg cttcaatcaa atcaatgtca tcaattgtca actgagcctt
    45481 tgcaagagcc tttttcgtag caggtattgg tccgcagccc ataatacttg ggtctacacc
    45541 tgcacttgca taactagtga ttttagctaa aataggaagc cctaattctt cagctttttc
    45601 tttactcatc aataaaattg ctgctgctcc atcattgatt cctgaagcat taccagcagt
    45661 tactgtcccc tcatctttga taaaagcagg gcgtaacttt gctaacttat ccactgtcgt
    45721 tccaaattta gggtattcat cttgatcaac gagtaaaggt tcacctttac gctgaggaat
    45781 agtgacaggt gcaatctctt ctttgaaacg acctttttct atggcaagtt gggctttacg
    45841 ttggctatca gctgcaaagg catcttgttc ttctctggtc agtccatact gttgcacaat
    45901 attttcggct gttataccca tgtgataacc tgcaaaagca tcactcaacc catctttaag
    45961 catggtatct actactttac tatctcccat acgagatccc caacgttggc cttgtaaaac
    46021 gtaaggtgct tgactcatgt tttcggtacc accgactaaa acaatatcag cgttgcccgt
    46081 ttgaatcttt tgagcaccta actcaactgc ttttaagcca gaaccacaga ccatatcaat
    46141 cgtaaaagca ggggtatcat aagaaagccc cgcatttagc gctacttgcc gagcaacatt
    46201 ttgacccaga cctgcatgta acacattccc aaagatcact tcatcaatgg catcactttt
    46261 aagaccggta tcagctaaaa tttttgtaac aactgtcacc cccaaatcta cggctgataa
    46321 agatttaaag actcctccaa aatttcctat cggggtacga taagcagatg tgatcaccac
    46381 ttctttagtc atagaaactt ctcctttttc attattgaaa cgcttacatt tttattatat
    46441 aatgtgaact ataataaaca aatatcgttt ttttatatat gctataacta aacgttatcg
    46501 aaagaggaaa atatgaatat ctcaagcttg gcttatttta ttgagattgt taattgtgac
    46561 tttaacttaa ccaaagcagc ccaaaaaagt catatttcgc aacccgccct tagtagttat
    46621 atcaagacta tcgaaaaaga agaaggagtc gttttattcc agcgtcaaaa agggcgtcta
    46681 gttggactaa cctcagtcgg cgaacgcttt tttgaaaatg ctaaggtggt tatcgcatca
    46741 catgagcaat taatggctga tttgcggagt gaatccaaaa aatacaaagg agaaatttca
    46801 atcggtattc ctcaactcat ctctggcatt gttttttctg agctcattcc aaaactcatc
    46861 gaagaaaatc ccgaagctaa atttcatatt gtagaaacgg gtgcttatga actgcaaaaa
    46921 aaactgtttc taaaagaagt cgattttgcg attttattaa cacccactac actagatgct
    46981 actattgctg atatcgacat tctcctaaga gatcaactct gcctttatat gagtcacaaa
    47041 acctttcaag agacgtttga tagtaatcct aacatctcta tcaaagcatt acatcgtcaa
    47101 aacttagtaa cttttgataa aacctttatg attaatcatc agcttaccac cttatttgaa
    47161 gaagcaaata gtcttcctgt agtcaaatgt tattctgcct cgtgggattt tttattaaat
    47221 tgcacgcgct attcctctta cctaacaatc ctaccaaggc ctattactca ttttgctcat
    47281 atggacggtt tagtggaggt ccaactgacc gaacatccaa aatgggaagt tgttctagcc
    47341 tctctcaagc acaataaaac aagccattta aaacattata tcaagcacac catcttagat
    47401 tatttcatga accagcgctt ctaattgctt gactcagacc ttaaaaaaaa acgcctgaag
    47461 gaaacaatcc caagcgtttc atgtagttat ttcctaaaat acaaataggt aaatgatggc
    47521 aatacctgtg accaccaaga cacaaggaat agtataagcc acaatttgat tgaattttag
    47581 tttgaagttt gagagataag ataaggccca aaaaggaact atcaagtttg ttgtggcatc
    47641 tcctaattga taagcctgca aaatcttacc tagatcatta ccgacttcga tagttgcagg
    47701 gacgatatat ggagcttcaa tcacaaattt tgagcctcct gatggtaccg caatattcag
    47761 caaagccgag taaagataag caaagaccgg ccatgttgtc ccatttgaaa tagcgacaaa
    47821 gaaatgggaa atctctagtc ctagacctgt actttgaatg attccaaaaa taccagcgta
    47881 aaatggaaac tgaagcacca agccccaaga tgacatgacc ccatctttga ataaggaacc
    47941 ataatattct ggtccttgtt gaccacaaag aagcaaccct aagcctaaaa ataaaaagtt
    48001 aaaactattg agatctagac cagacaagcc caccaccgaa aaatgataaa ggctatagct
    48061 aacaatggcc ccaccaacaa gatacatcac taagcgagat gcgttcatct tttcagcagg
    48121 tgtgtttctt gcaataacaa catgtgaagc ggtatcaaga ctatggtgat agatctcatc
    48181 atcaagttcc atgattttag tttcatcttt tgggtgcgcc aataaagcaa agcaaagcgg
    48241 taccagcata cacaccacta aaagactgat aaatggaaga ttcaaaactg attctgtcag
    48301 aggaacactt tcaggaacaa cctgtttata agcatctgcg acactatttc gcaaataatc
    48361 tggagtagcc gaataaagca ccgcagcacc agataaacca gaagtagctg gtaaaaaggt
    48421 aaaaaataaa gtagcaacaa acaaaggtgt atgcacctta atcccttttt gcctagcctg
    48481 aacaagcaac tctttcccaa acacaatggc aaccatcata ccaagacccc agtgtaaaaa
    48541 gccaaagata gaacctacta caatagaaaa aataaaaatc tgagtcctgg tttgaggcag
    48601 tttggcaagg gacttaaaca ttttatgagc aggtggagaa ctcgctacag cattccctgt
    48661 cgcaagtaaa atagtcatct gcatggcaaa ggacaacagc ccccaaaaac catttaccca
    48721 gccatagata atcccgcccg tcttttccgt accaataaag ggactatccg tcatcaacac
    48781 agacatagta acgactaaaa aggttaaaat aaaacagata aaaagcgatt ctggcatcca
    48841 tttcataaag ccatcaatat agcgatccat aaaccttttt ttggttttga tgttattcat
    48901 gttgtcaatt cctttcacat tgtccacaag cacttttgtt cttttgatca gtaacctatc
    48961 gataatacta ataagcgttt ctttagttca tttagttatc aataagttta aacccacaaa
    49021 aaacactttt gttccctttt tattatgaca acgttttcat agacaaacaa ctatgatttt
    49081 tttattgctt ccataaccct tatttatagc aaaaagaatg acgcttcact catcaacaat
    49141 gtctttgtta tatttaaata attaaaaaat tatgataaaa aattaaaaaa taatttactt
    49201 tttagttttt ttgatataat atattagtat taaaagaaag gtttttcatg atatgaaacg
    49261 atgtaataaa tatctcttca cttcactact agcagcttcg atgctgttta gttcgtataa
    49321 atcagtacat gcccatgata acattgatga aaaaggtaaa gtgcaccttt actggcaggg
    49381 aaattactag gttgataact atgtcgacta tactaaaaca ttggtcgata acaataacag
    49441 tatcgaatgg actgtaacct ttaattcagc taaagaacaa tgggtttacc ctgatttctc
    49501 agtgtttctt cctaagggtg taaaagctcc tacggagata acttatgagc atcattatgg
    49561 gaacggtaca gttgattcta aaaaacacaa taatacacaa tggcattatg attggggaag
    49621 ccaacaaaca aattttaatc aagaatttga taaattccct ggttatactg gctggagtcc
    49681 ttctctagat aaattttaca aactaaaaaa cgacggaaaa ttttctcacg ttttagtaga
    49741 cacctacggc cgtcaatcgc acacttattt ttctcataaa atggtttgga agtttaaaac
    49801 tgagcttgaa gataattaca aagataaatg ggataaatta ccgtttatag caggtattaa
    49861 acaaaacaac ccattagcag catcattccc aagttataaa ggggagttcg gtgagtaaat
    49921 gaagctgcca gtccatcatc ttttgcataa ttacagtcag agtctgagac aacatgattg
    49981 ctcagactct ttttattatg cttgaagtgg ccgaaatact ttcgtaagtg ccccacaaga
    50041 ttaaaaaggc agaaaacttt ttaaggctct gcctttttga actacttaaa atgacttatc
    50101 tagtgaaccg agacgatcga ttccagaaaa agaggtccac taacaagtgg accctttttc
    50161 gctattgtca ccaacagctt atcttaacat gatgataggc gttttttggt ttttagtgat
    50221 attacaaaaa cactactaat aagtgagcaa gaagtaacca tccaaaagaa catattatgt
    50281 tgcttctcac cagttgctgg taaactagta ttactctttg gcttatcttt tttaggaatc
    50341 tcagagttac tttctgattc cttgttatca aagtggaagg attgtactag tttagtatct
    50401 tcgacttccg ttttacaacc agaatccccg tgcatgccag tttgggtatc ctctgttgtc
    50461 tcgacaacct gcccctgacc gccaatgata acgtctgaag acttgctgtc ttctatttca
    50521 gtagttgagc cagaatggcc tgtcatacca ctttgtgtgt cttctgttgt gtcaacaact
    50581 tcaccttgac cgccaatgat aaggtctgaa gatttactgt cttctatttc agtagttgag
    50641 ccagaatggc cttgctcgtc tggaagcttt tcttcaatat caataacctg acctgaaccc
    50701 ttagttggct tgtaagcatc aaccatgaca atatgagcgt cacctttagt tgctttgcca
    50761 tttacagtaa cctgaccttg ctcattaact gtaaaggtaa tagcagttgc tatctcataa
    50821 ccgtctggtg ctgcggtttc gacaaatgta tattttcctg gcatcaggta gaaatctttt
    50881 acttgtccat ctgaaatcca tgtactaata gttttaccag atgaatcacg caactccata
    50941 gttgcaccag ctaactcttt gccgtcaata tcacgttttg agaatttaat atgggtagca
    51001 ctatcttctt caattgtcat atcaccggac tgaccttgct cacttgataa acctgacaag
    51061 gtatcaactg ggcgtgagtc ttcgacagta gtggtaccgc ctgaagcacc tgattctagc
    51121 ggaagcgttt cttcaatctc tagtttcggt ccttgttgtg taataacctc acgtttggta
    51181 ttaataatat cattagctga gtaagtcaca tcataacctg ttggaacagt tacttctcta
    51241 acagagtaaa tgatgtcatt acctgttcca ttatacttct tcaagttttt aaactcaaat
    51301 gaccactcat tacctgagcc agaaataaat ttggtttgac cttccacagc cactccatca
    51361 gcataaagct gcacttgaat ggcttgggga cgattttctg ccgtatcatt tttccaaatt
    51421 ttcttacctt tgaaagacgt tagcgtgtct tcatcaatga tttttgaccc agattgacct
    51481 tttatttcag catttccaaa ttcaaggtta aagttattct gttcaaacac aaattctgtt
    51541 tctctggtgt taaatatatc atttcctaaa tacgacacct tgtagccgtc tggaactttc
    51601 acttcttcaa ctgagtactt atactcctga ttcctgtcat cgtacttagg caagtctttg
    51661 aagtgataag accaatcgtt atccttcgtt acttcttgaa ctttatcgga cattttttga
    51721 ccattttgca acagttgcac ttgaatcttt gcaggacgtt gatctggtct gtcattctcc
    51781 caaattttct tccctgaaaa cgtaagggtt tctttatggt tgacaatcgt gacttctttg
    51841 ctatcttcta cttttacaga cgaatgtggg cttccccaag tgaccatttc ctcagcaggt
    51901 ttggtagtat caacagtaac ggtcgccaat ttctctgtca cctgctgata gcctttaggt
    51961 gcttgttttt catacaagtc gtaggtgccc gaggtcaggt ccttaaaatg aacctctcct
    52021 tgtgtgtttg attttgcttc tactttttga ctattaccat ttgatgaacg cagctcaaag
    52081 gccgcttctg gcaatggcac attgtcagtt gacattttct taaagcgaag ctgagccact
    52141 cgttttagat ttgctactgt aatagagggc ttagtaaatt cacttgtccc agaaccacta
    52201 cccttagaag gagacaaggc aatttcgttt tggaagtaga cgttattaac aggattacca
    52261 taagttacag cagtttcatt attaaaactg gccaaattgg attgaacgac tagtggctta
    52321 ccagattgat ccgttttccc tgttatttta acaacaaagg ctttattttg aagtttatct
    52381 ccaaagtcaa ttcgcaagcg cttattagaa ttttgagtac tatcttgtgg taactttgcc
    52441 tcaaggtctt ttcttaaatt caattttgtt agatcaaccc cataactagt gggtagcgta
    52501 tagtcctctt taacttcata aatttctact ttttccaatt gggcactact tgtagcggaa
    52561 tcctctgact tacttgttga gttattagat ttaaccaacc ttccaaatcc ccataaattc
    52621 atggtcgcat aaggaatatt ggtacgattt gggttgacat aaacatacca agtaaagtcg
    52681 cctgtttgtg tattgtagct ttcaatactt ccacccacat tgctcaatcc gttagtaaca
    52741 taattgttgt cttgcccaga tgcatttcca taaaggacat taactgtccc accatatttg
    52801 atttcctgat cacctatggt actcttaaaa tctgatatcg tttgattttc taaaacaacc
    52861 ttattctcta ggaataagct caattctgca gacaactgga ctttatctaa accagcgata
    52921 taatttgtaa aagtataggt gagctgatga gtcttggcat cgtattttcc aatcgcaagc
    52981 ggactatttt cactgtcata aatgatttta gggatatctt gactgatacc tttaggattg
    53041 agacgtttgt ccagctgtaa cacaaaggta tcgcctgggt tgattgtttc agatttatcc
    53101 ttttgtttca actcaaaaga cattttaaaa taggcggcat gattgcggta gaaatccgct
    53161 gcgccactag ttacttctgt ccctccgtat ttagagaata cagacattgt tgatttttcc
    53221 aactgtaaag aactactaac atcttttgac cctgctttac tgatgatttc cccattatag
    53281 ggattttcaa ccaacttggt atagccgttc tcataaacag tcactgtcca agtccgactg
    53341 gttttatcat aaccatctgg tgctttatct tcttttaagg tataagtccc tggttggaga
    53401 ttttgagcat ctataatacc ctcttcgctt gaggtaaagg tctgaacagg ttttcccttc
    53461 ccatcctttg gtgtcagtga aaaagttgct cccgataagg gcttattgtt ttggtcgact
    53521 ttcttgattt caaaagatcc ttgtttgttt gctccatttc ttgtttccgc atgtcctact
    53581 gatactccgg acaatcctat aaaaaccaat aataaaccta aaataaatcc tgttaaggat
    53641 aacaggaagc ttaacttata gctatttttt tgtgtcattt attttctctc tccacattca
    53701 taagcgacag cctatgtcca aaactaaaga ctacaggaca actgtcaaat agttatttta
    53761 ccattttcag ttgtcaagtc tacatcttat ggtcagagta tttattttga tggtttttta
    53821 gcgtttttta tgtcattatc tgtaactctt tctttttcaa gcgcttaacg tacaaatcct
    53881 ttatctttat ctgcttagct atttatagta taattaaggt aggagatgat ggagagagag
    53941 tttactatta ggaaaacctt ttagtgtgcc taccaaatag gaattttcat cattaacatt
    54001 tactaaagct tttacaagtc taaggaaaat gatacaacta aggatggggg gcaatctatc
    54061 aaatggttat attcgattta aaatatgtgc aaacattaca cagcttgtct caattaccta
    54121 tttcagtgat gtcacaagat aaggcactta ttcaagtata tggtaatgac gactatttat
    54181 tatgttacta tcaattttta aagcatctag ctattcctca agccgcacaa gatgttattt
    54241 tttatgaggg tttatttgaa gagtccttta tgatttttcc tctttgtcac tacattattg
    54301 ccattggacc tttctaccct tattcactta ataaagacta tcaggaacaa ttagctaata
    54361 attttttaaa acattcttct catcgtagca aagaagagct cttgtcctat atggcacttg
    54421 tcccacattt tccaattaat aatgtgcgga accttttgat agctattgac gctttttttg
    54481 acacacaatt tgagacgact tgccaacaaa caattcatca attgttgcag cattcaaaac
    54541 agatgactgc tgatcctgat atcattcatc gccttaagca tattagcaaa gcatctagcc
    54601 aattaccgcc tgttttagag cacctaaatc atattatgga tctggtaaag ctaggcaatc
    54661 cacaattgct caagcaagaa atcaatcgca tccccttatc aagtatcacc tcatcttcta
    54721 tttctgctct aagggcggaa aagaacctca ctgttatcta tttaactagg ttactggaat
    54781 tcagttttgt agaaaatact gacgtagcaa agcattatag ccttgtcaaa tactacatgg
    54841 ccttaaatga agaagcgagt gacttgctca aagttttgag aattcgctgt gcagctatca
    54901 tccatttttc cgaatcatta accaataaaa gtatttctga taaacgtcaa atgtacaata
    54961 gtgtgcttca ttatgtcgat agtcacctgt attccaaatt aaaggtatct gatatcgcta
    55021 agcgcctata tgtttccgaa tctcacttac gttcagtctt taaaaaatac tcaaatgttt
    55081 ccttacaaca ttatattcta agtacaaaaa tcaaagaagc tcaactactc ttaaaacgag
    55141 gaattcctgt tggagaagtg gctaaaagct tatattttta tgacactacc cattttcata
    55201 aaatctttaa aaaatacacg ggtatttctt caaaagacta tcttgctaaa taccgagata
    55261 atatttaaga attcaagaca ctcttttcat caatcattat cttatatggt acaaaaacct
    55321 atcagcatag aaaacatctc caaagtcaag caagactatg gagatgtcaa taagtttcat
    55381 tataaaaata gagcaactaa aaatgtgtga ctcttaaaaa tgggttttat agcctactct
    55441 tcagtttttt aacataaaga agaactagta atcccagtaa tacgatactt aagataccca
    55501 ataaactttt tacttcacca gctaatggta atggggtttt agggatgtca ggttgtctag
    55561 gcggtattgg ttttactaac cgtttgggct taaaagtaat cgctgatttt tcttcgtctc
    55621 cagcccttcg agaaataact tttgcggcta gagtctcatc ttcatcatag gtcacataga
    55681 caagaacgtc aaatacagta gtatctgctt gataatcttt attttgtgaa ggcttctgat
    55741 aaacacgata agtatattgc ccaactgttg tgaaggtcag aggggaaaag cttgcttttc
    55801 cagaaccagc aattgttatt tcttctattg ttttcatcgc atcaattgat tctaatgcaa
    55861 tcgaaaatgg ggtactatcg cctgctctct ctaagacatt ttcgacacta atgctagttt
    55921 gaacagtgct gtcttttgct aaaacagtct gattaaaggc cagcatggtt aatatcatta
    55981 cgacagaaaa taacattttc caatattttc tcaaaagtct cctcctttcg ttattcttga
    56041 atagtaccga caacgataac acgattgtca gtagaaaaat tttcacacgt tgaaaaagca
    56101 acgaactttg tatgatgctt caatttaaca ggtttaaatt gttttgatct tttactgata
    56161 taatcaacaa gctgcctttg ttggtcttga ttggtaatag cattaggatt aaaaactaac
    56221 tggtcaaagg catctgtctt gagacaagca aaaatagtga cggttagttt ttttctctct
    56281 tttgtttcaa tgatagcttt attatgtttg ttgaaaaaat ccttttttaa aaattttgga
    56341 atttcgccaa acatggcatt acctgccata tgatggccat aaatcagaga gtaatcgtcc
    56401 gtaaaattat tatgattccg tgtatctaaa aataaactac cagacatggc aacactgcca
    56461 tcaactgctt tattaatata ctctaaattc gtttttccct gaactagagg ataatcaata
    56521 tgagtccctg ggatatttaa ccaaccaatg acatcctcat tcaaagctaa caagtcttca
    56581 aatttaggct gttgttgagc tgttttaaat tttttgaaat tagaagcgtc tgcttgttga
    56641 tagagatgat aagaatccca caaaccaaaa ccagctaaaa atagtacgac taaacaaaag
    56701 ataagaatga gagtatcaat ggctttattg ataacctgta caattgtcat catcattctt
    56761 tgactaatca cttaagcttt tttacgtttt gtaatataga taactccacc aatagccaca
    56821 atgctaagaa ctgcaaatgg agcaagggtg cctacaacac cagttggaac ttgagtgtca
    56881 cggttatttg tgacaacgat ttcgtcagca gattcgtcag ccaattgttg atttcctaac
    56941 ttatattcca caggcgctgc cgtaccatct gtaattttgg cattagttgt gtatccgtct
    57001 ttatctgcct catcttcaat gatgctataa gtaacaccta ctggtaattt tgataaagtt
    57061 actttctcac cattctttag agcaaattta tacggctcac caatcttaac atcagcttta
    57121 attccacctt tctctaattt aataacttgt ccagctacga aattatcatt aggattaatt
    57181 gtcaaagtga aattgaagtc tttctttagt tctcctgtat taccagtcac ctgtttttct
    57241 acctttaaag aagttgtctt aaaggagttt tcaaaaacaa caggcttttt atcattttgt
    57301 cccttctctt tagatacaat ataccgtgcc ttaaatcctc cattaccatc attaacaaca
    57361 taaacatcca ctatccatgt tttggtatcg tatttaatcc cactaacttt gctatctatt
    57421 tctgaaaccg tataacgata aacaccaact tctggaaatt ttacggttga aaaatcaaaa
    57481 gttgcagtct tagatttatc cgatggttta actgagttat cataagcaat tgtctgctcg
    57541 gtagttaaac cttcagttac tcctggctta atctctaaac catctttcgt tttatcagtt
    57601 gcagaactat ctgcctctac tttaaaagta taatcagctt ttggcattaa aacttcattg
    57661 tctgtataag agtcaaatgt cttttttact attaattttg cattttcgga cactcctgcc
    57721 gtctcagatt ttacgttttg atttaaagaa gctgttccta aagcagttgc taagattgca
    57781 gtagcaagta ataatttatt ttttttcatt ttctctctct ccaaattttt ttaaattcct
    57841 ctcactctta atagagttga gattttccct ttgatttgat tgatgggtaa cgccccataa
    57901 taacgactgt ccaaacgttc ttcacgataa tcattcaata tgaaatacgt acccgtagga
    57961 actttatagg gaaaatttgg gccacttgag tgaggatacg tcaggtaagg gacctctttt
    58021 tctggtggat gcccattaat caacagtcct ccttcttgcg taaaattaac ctcatcgcca
    58081 gcttgagcgg caattcgacc aactttcaaa gtgttatcaa cctcatagac caccacatca
    58141 ttaatatgat agcgatcagt caaacgataa tataagactc catcaccagc acttacagca
    58201 ggactcatct gatttgtgtt aacaatcatg acgccaaaaa catactgaaa tagaatgtaa
    58261 cctagaaatc caataataga aatcttaagt actaaccgta tgaaagcttt aaatagtgga
    58321 ttctcattta agcgatttag gtaattagtc attttttagt cctttacgac caaagaacca
    58381 cactaacaaa ccaaatggga caagcaataa taaccacaga taggttccac catcagtagt
    58441 aaaaccagtt ggtgggacaa gatctttacg gttttcaaaa gtgacttctt tgtctgctgt
    58501 gacattctca cttgctgatt gagcttcttg actaactttg ttatcaacgg ttactatata
    58561 atccttagct tcagtctctt tcagagtata agaatatccc gtcggtaatc cttctattct
    58621 tatggtgtca ccatgcttta gattaaatga atatttccca tctttagcta ctaaatcttg
    58681 attattagtt tttagagcgt cgacaatagg ctgtccagtt ttatctttca actcaagttc
    58741 aaattggaag cctttagtct tatctcccaa ctcaccgact actgtttttt tcaccgtcaa
    58801 actatgaatt actggaataa cttcttgctt tttatcttcc atacgaatca cgtcaaccaa
    58861 atcatctgga tggtattctg tcccaataag agattggtat ttgctattat taggtacgaa
    58921 gaaatcaaga tttgttagtt ttgaatcttc atcactcaaa gcgtattcta caattttttt
    58981 agctacaccc aaagtttgat cattcatatc tccaaatcca tggaagtctt tcaatctatc
    59041 cttagttaag tcaacactat ctgtaaaata ataaattgcc agttgagtag ccgcgcgaaa
    59101 ctgtgcctca gtcagaccgt tatatggaat agcttgacct tttttatgat acccattttc
    59161 aattactttt tttacgtgtt ttaaaaataa ttgaggatct tcatccctag ctgtattagc
    59221 gtattttatc aaatctgaac cagcaatatg actataccta atatcaccag tcgtaaagtc
    59281 aggatttatt gtagcaccat gatcttccga gtcaggtggg gatttcaagt tggcattgaa
    59341 gcaataaaca atttgtgaac tgccatcata gttttttcca taataaaatt tcgcataatt
    59401 ttgtgttgac agtaaaccaa attcatcaaa atcattgtat gcctctatag tatatggaga
    59461 acctacttct ttgtttggat tttccacttg agaaccatct ttttggacga taaatacttt
    59521 tttattcact actctaaact taatcggctc cgcaatttta tatccatctg gagatgatgt
    59581 ttctgttaag gtataagtcc catttgataa ttcaatcttt tctcctgttc cattactttg
    59641 gaagactttt tcttgaaaat ctgggatatc ttcccctgtt aaacgcaaag ttgctccctc
    59701 tagaagttta gagtagtcac cttccgcata ttttctgata atgactgatg ttttttcagt
    59761 tttagccgga ggctcttctc ctggttttgg gggagtatcc ggaacatact cagcactcaa
    59821 aagattttgg aaagtcttat catgagattc aaatacattt aaccgataac ctgatggagt
    59881 tttattcgaa tattttgacc ctaagtttgg atcaattagt tcttttaaag cttttcgcat
    59941 taagcctaac tgctggtcat taataccatt actttgagct tctgttttaa aactttcatc
    60001 cggattaatt tgagctgaat cagaatagta ccatacagcc tcttgagtga ctttaatagc
    60061 atttaaaggc tctaaatctt tcataatgcc attagcatca ttaggatagg cattatacat
    60121 aacagctagg agttttttgg ttaactcctc tttacgaact cttggttcca tagcaagaga
    60181 atcaaaattc tcagcagttc catctaattt tttataccac ttccgatcaa aactctggga
    60241 ggaacgggga tagtgtttgt gaacgttaaa gcaatatact tgataacttt tactcccatg
    60301 caaattcact ctcagatcat gatagtatgt cttgaataaa tcatacttcg gatacccccc
    60361 tgtataggct tcatagccat accactgata gtctgactgt ggatctggat tgtgaaaaat
    60421 aggtactggt acctcaacca attcgtgagc tgctcgaact tttccttcaa atcctatcaa
    60481 tactaagagc attaaaaata ctcccactaa agtgacagtt aattgttttg gctttctgtt
    60541 tgatacccga ggagcatctt gcttcttttg caattttttg ttattcattc cctctccttc
    60601 tgaataaaat cttcagtccc atccctttac cggacagtca caatgctatt tcatagctac
    60661 tatatcattt atttgatgtt taaaacagtt gttcttatca tctttttttc catattatgc
    60721 gttccaaaaa ataatttttg ggaaaatcat ttgtaatcgc ctaatatttt tctcttgatg
    60781 agatttaatt aaacttcatc aaaggggata gtaactacca gattatttta cttttatgac
    60841 agttgcaata cgataaagaa ggttcagggc aagttagttt ttaatcactt ttttatcagt
    60901 catctttgaa tacataaata ctaaaataat agctataacc accccgaaag cagcacatac
    60961 tacttctgtc cacattcttg atttatccac gagtttcatt gcttttttag cctgttgata
    61021 ctttttgtaa tgatatgcaa ttctatgacc tctgaccaat agacgcttgg tattaacacc
    61081 atatggtgtg caggtaacca gagtagcata atcttttccc attaccccag aaagagatgt
    61141 gacttgatct ggttcaacag ttagtatctg atcaacttta taagccaata ctttatttaa
    61201 cacacgaaag taaaaagtat ctcccctttt cactaaattc aaattagtaa acatttctgc
    61261 cgatggaagg cctctatgag cagaaataac cgtgtgagtc ccgtcgccac caactggtaa
    61321 ggcacttcca actaagtgac ctgctccctt agttagcacc tcgtctgtcg tatagtggta
    61381 tatgggtaac gtcactttaa tagagggcac ttcaacatat cccataatat cattgttttc
    61441 aatttgaagt aggctttcgt agtttttatc atgaatgcca tccctaaatg aaaaagcatc
    61501 tggaacgggc tgaatcccaa gcctagcgtt atacgcctta gccttttgcc acacctcctc
    61561 catttctgag ggcttctttt gagtcacttg tttgtgataa gttgataaca attgacgatc
    61621 acggtaggca ttccactgac tacttagcgt agggtaaaga aaaatggctg ttcccaataa
    61681 aaataataag agtatcccta gattttttag tctttctgtc attgcagttc cttatcaata
    61741 aaaatcgaga ctgcctaaag acagtctcga ttgatttcga cttttgaaag cgttaagctt
    61801 tacgacgttt aacaataact tgatttcttg taagtctatt atgcatagaa tacatcattt
    61861 tttagccatc ctacttgctc tgaattatct gtcaccttat tattatcaga tgtataagta
    61921 gtaccttttg aattaacact tgtcttgact gtagcagtta tccactattc agcatatttg
    61981 cgcattattt cttatggaac acttttacgt cagactttat tgttttgttt gttttttaaa
    62041 aggctaaaaa tagaaagtac tgacaaaata aggattccaa gaaaggccaa aacatttcca
    62101 atatctcctg ttgcaggaag gataggtgtt atattttttg taggcttttc ccgattctct
    62161 tccactttgg gctcattatt gtcaaaatgg aacactaact tcggacgcgt atcttcaaca
    62221 atggtcactg tttcactgaa accgctcatg cctgtttgag tgtctttagt aaattcaaca
    62281 gactcacttt gacctcccat caatactcct ggctctttcg tgtcttctgt ctcaacctga
    62341 ggagttgttt gaccactcat gcctgtttga gtgtctttag taaattcaac agactcactt
    62401 tgacctccca tcaacacttc tggctctttc gtatcttctg tctcaaccat atttcctgaa
    62461 aaacctgttt cattcggaag ttttttatca atatcaacag ggttctgttg atttccatag
    62521 acttcggtaa tatactccgt ctcaccagac tcacccgcta gaggtgactg gtctttattg
    62581 ttaaactcat aacgaggaac ttcaataggt aagtcaacac taggtttttc agggacttct
    62641 tgaccatcta actctggcat caatggggga agcgcaggtt ctaagctctc gcttggaact
    62701 tctgggactt cttcaccatc tagctctggc atcaatgggg gaagcgcagg ttctaagctc
    62761 tcgcttggaa cttctggaac ttcttcacca tctagcatca ctggcggcaa tgtaggttct
    62821 aaattatcat ctggatgttt tgggtcttcg ggaataggac taccatccaa ctcgggagtt
    62881 ttaggattat gttctgacgt atcaccaggt ttagggggat catcaggtac aaactcagca
    62941 cttaaaagat tttggtagga cttatcagaa gactcaaaag tactaagttt aaagttcgat
    63001 ggaacttgtt taaccaaatc ttcatcagag gaaattagtt tcctcagggc ttcacgcatt
    63061 aaagtaactt gtgactcact aatcttacct tctttcgctt cagacttcca taatgtctca
    63121 atttcatact gtgacttatc tgaatagtac caaactgcgt attgtgttac ttctatagca
    63181 tttgaaggct ccaaaccttt cataatatta ttgccgtcat tagggtagcc gttatacata
    63241 acgctccgta attttttagt tagttcctct ccccctactc tgggagccat agcatgaact
    63301 ttaaaagttt cagcagttcc ctctaatctt ttataccatt ttttatcact actcgtaaaa
    63361 ggtcgaggat agtttttttt aatattaaaa caataaactt ggtagctccg acttccgttt
    63421 aaattgactc taagatcatg atatcttaaa aacgctccag tataagcatc ataaccatac
    63481 cagggataat ctggatctgg gcttttaaaa ttcggcacag tcttctcatc cgcagcatag
    63541 gctacttgac caaaaccgat agcacccgcg catgccaaaa gcataaaaaa gactcccact
    63601 aaagtgacag caaatcgcct ttttcttttt gtgtgtgcca aaaaaccggc ttctttattc
    63661 aaaaatattt tgttattcat tttctctcct ctc
//
LOCUS       DATWEK010000008        57006 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.008, whole genome shotgun sequence.
ACCESSION   DATWEK010000008 DATWEK010000000
VERSION     DATWEK010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57006
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.008"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..949
                     /locus_tag="VCR92_000601"
     CDS             <1..949
                     /locus_tag="VCR92_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEP4267690.1"
                     /translation="QELGKGITAINKAYRPGEGVKARKEAAKADLEREAAKVREAIAN
                     DPTLTKADKAKQTEAVAKALKAAIAAVDKATTAEGINQELGKGITAINKAYRPGEGVE
                     AHKEAAKANLEKVAKETKALISGDRYLSETEKAVQKQAVEQALAKALGQVEAAKTVEA
                     VKLAENLGTVAIRSAYVAGLAKDTDQATAALNEAKQAAIEALKQAAAETLAKITTDAK
                     LTEAQKAEQSENVSLALKTAIATVRSAQSIASVKEAIDKGITAIRAAYVPNKAVAKSS
                     SANHLPKSGDANSIVLVGLGVMSLLLGMVLYSKKKESKD"
     gene            complement(1135..1251)
                     /locus_tag="VCR92_000602"
                     /pseudo
     CDS             complement(1135..1251)
                     /locus_tag="VCR92_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611995.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1814..1975
                     /gene="sagA"
                     /locus_tag="VCR92_000603"
     CDS             1814..1975
                     /gene="sagA"
                     /locus_tag="VCR92_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TOMM family cytolysin streptolysin S"
                     /protein_id="HEP4267691.1"
                     /translation="MLKFTSNILATSVAETTQVAPGGCCCCCTTCCFSIATGSGNSQG
                     GSGSYTPGK"
     gene            2197..3147
                     /gene="sagB"
                     /locus_tag="VCR92_000604"
     CDS             2197..3147
                     /gene="sagB"
                     /locus_tag="VCR92_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S biosynthesis dehydrogenase SagB"
                     /protein_id="HEP4267692.1"
                     /translation="MSFFTKEQQPKENCPPITVEKARQLFEFNTNHLSLSDYHHQTVL
                     KTSKQLVAQHLMPNATDNLSQHFLMNYKANNNYLGFQASIVDFFTDSAVANFSSSYVY
                     ESQEKIIRLPKPTKISTALSTCIIKRRSHRQFSDRQMPLQDLSNILYYACGVSSQASI
                     RDGASDKITLRNCASGGGLYPIHLVFYARNISKLIDGFYEYLPYQHALRCYRHSSEEN
                     VRDFAEYGAINAENCNIIIIYVYHYMKNTRKYGNQATAYAFIESGEIAQNIQLTATAL
                     TYGSIDIGGYNKEYLQELLDLDGLGEHVIHMTLVGTKESQ"
     gene            3144..4202
                     /locus_tag="VCR92_000605"
     CDS             3144..4202
                     /locus_tag="VCR92_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEP4267693.1"
                     /translation="MKYQLNSNVRVVTFQDTFCFRKGIWDFNEAILDLTQEPQNLKIV
                     YQEIVSQLVKGVAIDTETYENTLEPEMFANLMEVISGLYYNDMLMLEDDYNLEENVMK
                     ILMGNFRFMAQAGHMVSNAPVLFISDSTYVNESAELLAEQLHLQLQVASDDLKMLIQQ
                     TDVSSRLDALEHRRNMNCLSEALCDYQSIIICQERLNIMMLRHLNEVSVAMKKQLVIG
                     FVDGPFLHTCTLNPPHSADFDSLERRVLARLQDSTLYQHFANQILPATQDVSQAYLPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSIYLPTLEIQVQDILKMSNSQTQGALAKLK
                     YEDQQISTREIVKKLLDE"
     gene            4222..5580
                     /locus_tag="VCR92_000606"
     CDS             4222..5580
                     /locus_tag="VCR92_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEP4267694.1"
                     /translation="MLYYYPSFNHIFDELKSLSGNRTGILNQSQVPVCNHPHDVYLKS
                     ITGQMPDYHKQFIGELSQVSYHIIGYGSYYEEALIKYLGESIERYATVIAGDLLSDRI
                     VYASYNELKLLHKVMPLEYLQVFTQEQIALSCDLQMMMCDKMVTENDVLGWVKCPMFF
                     EDAEMYVPAQMLCVGYKTNETVGERRIIPGFSTGTASHKTLEAAMCNSLIEYIQIDSM
                     MLSWYTKKPCPKIIVDDPDIEVILEEARLGKDSLYDIIPIDMTVGEDNPLYTFGIILK
                     NKYDEGPYLLFGVQAGLDPKHALLRGIMEASAISYSYYYNLLYQKASLANIECEEPLF
                     LDLDSNVFYYAHPKDQDHKWKAFEPLISGEVLLSDLEDHSGKDKKEDLKTLLAYAKKV
                     SPNAVFLDITPPEALEKGWYVTRVLMPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            5555..6226
                     /locus_tag="VCR92_000607"
     CDS             5555..6226
                     /locus_tag="VCR92_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEP4267695.1"
                     /translation="MPLSIQCLNLCFLLVTFCPSIPMQAIFGKEDSGYAFNLIGFLRA
                     TLIYDILALVSIYVLSPQITLSLESIDSKTFFMGLVFCVLIVLIELVFLHGLRCWQKK
                     QWLPATFSFVGTTNDWSKIGYPLLLALFEETIYRFLWFNILAFQWHLPTIIVLIVTSF
                     CYALNHLLMGKSIFYAKLVTGIIYGSIYMLTSQLWLVVIMHVGGNLLVECLSHLQTKK
                     KKGVT"
     gene            6223..6906
                     /locus_tag="VCR92_000608"
     CDS             6223..6906
                     /locus_tag="VCR92_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEP4267696.1"
                     /translation="MMLLVLLSFLGLTTLWLTSYRRRCLARWHLQWLVALSYQDFLDV
                     LLSLFQFVIIILVLFFYSATINLGEVLTFLTQTSWHWQILCYLVLYLMAIIEMTLLVL
                     ILIFDVLLQKDSRLLFKKITWLPFRQDKPVLSILLLGIAILVDSLFYLGLLILLGEQS
                     LTSLATLILGYGIVKACRYSGWLNVLLAFCLFTIVGLWAVTATLLYGWLVGAMILTVT
                     YLMISCKEY"
     gene            6929..7852
                     /locus_tag="VCR92_000609"
     CDS             6929..7852
                     /locus_tag="VCR92_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4267697.1"
                     /translation="MSFVQLTNVVKSYKNGKKAVNDVSLSIEAGNIYGLLGPNGAGKS
                     TLINLILGLIPLSSGKITVLGQSQKTIRKISSQIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGAQLKKQVLKSLEFVGLHSQAKQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNKEGATVIYTTHYMEEVEALCDYIFIMDHGQVIEEGPK
                     FELEKRYVANLANQIIVTLTDSRHLELADKPDWSLIEDGEKLMLKIDNSDMTSVVHQL
                     TQANITFSEIRHNHLNLEEIFLHLTGKKLRD"
     gene            7861..8988
                     /locus_tag="VCR92_000610"
     CDS             7861..8988
                     /locus_tag="VCR92_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4267698.1"
                     /translation="MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFN
                     TATTVPKLTIRYQLEGEKTDYQKNFLAFLKVLNQKLHLEAKPSNSLEKDRQRVSEGAL
                     TAVLEVKKNQTIKVITNNINQQNADLINMLVKNYVDNAKTYDSIAALYPQQLNHIRKR
                     SVDYVKVSSIQTSKGMTSADYYAISMFTMITFYSMMSAMNLVLSDRQQRITNRIHLTG
                     VSPSLLVFGKLIGAMLATTVQLSLLYIFTRFVLRVNWGTNEWMLIGITASLVYLSVAI
                     GIGLGISIKNEAFLTVASNTIIPIFAFLGGSYVPLTTLHSSIINQLSNISPIKWVNDS
                     LFYLIFGGQYNPIPVTLIVNISIGTIFIILALIGMRKQVTT"
     gene            8985..10103
                     /locus_tag="VCR92_000611"
     CDS             8985..10103
                     /locus_tag="VCR92_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4267699.1"
                     /translation="MICFIKTLFVKIKRKKTSYVTFFLMPILTTLLALSLSFSNNNQA
                     KIGILDKDNSQISKQFIAQLKQNKKYDIFTKIKKEHIDHYLQDKSLEAVLTIDKGFSD
                     KVLQGKSQKLNIRSIANSEITEWVKAQTNYLLENYNIIGDVALGNEDTFNRILQKNQQ
                     LNYDVKQVTLTDRSRSKAVSSTTTGFLLILMLGSTSVIYSGILADKSGQLYHRLMLSN
                     LSRFRYMLSYVCVGFVAFTIQIVIMLSLLKVFNISFFVPTSLLLIIFFLFSLLAIGFG
                     LLIGAITQNSQQSSQLANLIVMPTSMLAGCLWPLSITPSYMQAIGKLLPQNWVLSAIA
                     IFQSGGTLSQAWPYLLALMGTALALISFSSLLLKPTKL"
     gene            10675..13407
                     /locus_tag="VCR92_000612"
     CDS             10675..13407
                     /locus_tag="VCR92_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpnA family nuclease"
                     /protein_id="HEP4267700.1"
                     /translation="MINKKYIIPVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKR
                     ESVISDKSNFPVISPYLASVDFGERKTSLPTPDKGVKVTTEQSIAQVRKGPEERTYTV
                     TGKITSVINGWGGYGFYIQDSEGIGLYVYPQKDLGYSKGDIVQLTGTLTRFKGDLQLQ
                     QVTAHKKLELSFPTSVKEAVISELETTTPSTLVKLSHVTVGELSTDQYNNTSFLVRDD
                     SGKSIVVHIDHRTGVKGADVVTKISQGDLINLTAILSIVDGQLQLRPFSLEQLEVVKK
                     VTSSNSDASSRNIVKIGEIQGASHTSPLLKKAVTVEQVVVTYLDDSTHFYVQDLNGDG
                     DLATSDGIRVFAKNAKVQVGDVLTISGEVEEFFGRGYEERKQTDLTITQIVAKAVIKT
                     GTAQVPSPLVLGKDRIAPANIIDNDGLRVFDPEEDAIDYWESMEGMLVAVDDAKILGP
                     MKNKEIYVLPGSSTRPLNNSGGVLLPANSYNTDVIPVLFKKGKQIIKAGDSYKGRLAG
                     PVSYSYGNYKVFVDDSKNMPCLMDGHLKPEKTNLQKDLSKLSIASYNIENFSANPSST
                     KDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLIDAIKKLGGP
                     TYRYVDIAPENNVDGGQPGGNIRTGFLYQPERVSLSDKPKGGARDALTWVNGELNLSV
                     GRIDPTNAAWKDVRKSLAAEFIFQGRKVVVVANHLNSKRGDNALYGRVQPVTFKSEQR
                     RHVLANMLAQFAKEGAKHQANIVMLGDFNDFEFTKTIQLIEEGDMVNLVNRHDISDRY
                     SYFHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRASDHDPLLLQLSFSKEN
                     DKAESSKQSVKAKKTSKGKLLPKTGDSLVYVITLLGTASLLVPILLLTKGKKES"
     regulatory      13572..13687
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            13685..14185
                     /locus_tag="VCR92_000613"
     CDS             13685..14185
                     /locus_tag="VCR92_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEP4267701.1"
                     /translation="MTKLTVHDYVHIGLVAALYVVLTITPPLNAISYGMYQFRISEMM
                     NFLAFYHRKYIIAVTLGCMIANFYSFGLIDVFVGGGSTLIFVTLGVILFSKYQKDYLF
                     NGIFNKAFVYFSFFFATSMFTVAIELYFFGAPFLLTWFTTALGELVSLLIGSLIIDKL
                     SQRISF"
     gene            14379..16337
                     /gene="ligA"
                     /locus_tag="VCR92_000614"
     CDS             14379..16337
                     /gene="ligA"
                     /locus_tag="VCR92_000614"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEP4267702.1"
                     /translation="MKKRIKELTDLLNRYRYDYYTKDAPSVSDSDYDKLYRELVTLEQ
                     SYPEYVLQDSPTQQVGGTILKGFEKYRHQYPLFSLQDAFSREELDAFDKRVKAEFPNA
                     TYLAELKIDGLSISLSYENGFLQVGATRGDGNIGENITENIKKIKDIPHQLSEPLTIT
                     VRGEAYMSRQSFKAINEARQENGETEFANPRNAAAGTLRQLDTAVVAKRQLATFLYQE
                     ASPTARNQQNEVLAELADLGFSVNPYYQLTSSMDEIWNFIKTIEAKRDQLAYDIDGVV
                     IKVNSLAMQEELGFTVKAPRWAIAYKFPAEEKEAEILSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVIVYKAGDIIPAVLNVVMSKRNQQEVMLIP
                     KLCPSCGSELVHFEDEVALRCINPLCPSLIQRSLEHFASRDAMNITGLGPAIVEKLFL
                     AGFVHDVADIYQLTKEDFMQLDGIKEKSADKLLAAIEASKSNSAEKLLFGLGIRHIGS
                     KVSRLILEVYGDISALLTAKEEEIARIDGLGSTIAQSLTQYFEQKTAAILVDELKTAG
                     VNMHYSGQKVNSDAALFGLTVVLTGKLNQLNRNEAKDKLEALGAKVTGSVSKKTDLVI
                     AGSDAGSKLEKAKSLGIRIEDEDWLRQL"
     gene            16351..17373
                     /locus_tag="VCR92_000615"
     CDS             16351..17373
                     /locus_tag="VCR92_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEP4267703.1"
                     /translation="MKKQLRARLIYNPTSGQELMRKSVPEVLDILEGFGYETSAFQTT
                     AQKNSALNEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLKKRPKMAIIPTGTTNDFA
                     RALKVPRGNPSQAAKLIGKNQTIQMDIGRAKKDTYFINIAAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDKGVFEGQVSMIFAAITNSVGGFEMIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLILDGGKHITDRRVEYIKTSKIVIEPQCGKRMMI
                     NLDGEYGGDAPITLENLKNHITFFADTDLISDDALVLDQDELEIEEIVKKFAHEVEDL
                     EQELEE"
     gene            17765..17962
                     /locus_tag="VCR92_000616"
     CDS             17765..17962
                     /locus_tag="VCR92_000616"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEP4267704.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKAASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            17997..18713
                     /gene="atpB"
                     /locus_tag="VCR92_000617"
     CDS             17997..18713
                     /gene="atpB"
                     /locus_tag="VCR92_000617"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEP4267705.1"
                     /translation="MEEAKIPMLKLGPITFNLTLLAVCIVTIAVIFAFVFWASRQMKL
                     KPEGKQTALEYLISFVDGIGEEHLDHNLQKSYSLLLFTIFLFVAVANNLGLFTKLETV
                     NGYNLWTSPTANLAFDLALSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            18731..19225
                     /gene="atpF"
                     /locus_tag="VCR92_000618"
     CDS             18731..19225
                     /gene="atpF"
                     /locus_tag="VCR92_000618"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEP4267706.1"
                     /translation="MSITFGELVGNFILVTGSVIVLLLLIKKFAWGAIESILQTRSQQ
                     ISRDIDQAEQSRLSAQQLEAKSQANLDASRSQASKIISDAKEIGQLQGDKLVAEATDE
                     AKRLKEKALTDIEQSKSDAISAVKTEMSDLTVLLAEKIMGANLDKTAQSQLIDSYLDD
                     LGEA"
     gene            19225..19761
                     /locus_tag="VCR92_000619"
     CDS             19225..19761
                     /locus_tag="VCR92_000619"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEP4267707.1"
                     /translation="MTKKEQALIEQYAKSLVEVASEHHSLDALQADVLAILETFVTTN
                     LDQSLSSLAVPHAEKIKLLTLLKGNNSVYMNNFLNLILQNEREAYLYQMLQTVLNEIA
                     IVSNQYDVTVTSSLPLTEEQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            19777..21285
                     /locus_tag="VCR92_000620"
     CDS             19777..21285
                     /locus_tag="VCR92_000620"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEP4267708.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGL
                     DNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDVHYNDLFETIRTTKDLPEEAALDAAIKAFKEHSNFKS"
     gene            21301..22176
                     /locus_tag="VCR92_000621"
     CDS             21301..22176
                     /locus_tag="VCR92_000621"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEP4267709.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSELTIGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSV
                     MDMITEYHADGDYEIISIGSVGSDFFKARGMNVAFELRGLADQPSFEQVRQIISQSVD
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQQMLPISDLVADEAAEEGVTGFELEPNRHDI
                     LDQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKNVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            22338..23744
                     /gene="atpD"
                     /locus_tag="VCR92_000622"
     CDS             22338..23744
                     /gene="atpD"
                     /locus_tag="VCR92_000622"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEP4267710.1"
                     /translation="MSSGKIAQVVGPVVDVMFASGDKLPEINNALIVYKDSDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EEPFAEDVDRQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTQKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKYDDLPEDAF
                     RSVGPIEDVIKKAEKMGF"
     gene            23757..24173
                     /locus_tag="VCR92_000623"
     CDS             23757..24173
                     /locus_tag="VCR92_000623"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEP4267711.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKCISVTTPDGEMGILPNHINLIAP
                     LQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTVVADSAERDRDIDVSRAERAKLR
                     AEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK"
     gene            24439..24696
                     /locus_tag="VCR92_000624"
     CDS             24439..24696
                     /locus_tag="VCR92_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEP4267712.1"
                     /translation="MVCYNNPMELLMKIIAFSCHLFFIGLSYQLLISVIDWTKFSHYH
                     PENLGRLRLFVFLLATALGYLVSHCMLELLQISQTLFFEFR"
     gene            24761..26032
                     /gene="murA"
                     /locus_tag="VCR92_000625"
     CDS             24761..26032
                     /gene="murA"
                     /locus_tag="VCR92_000625"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEP4267713.1"
                     /translation="MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILR
                     NVPILSDVFTMNNVVRGLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMI
                     YMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQFLNKMGARIRGAGTETLT
                     ITGVTSLHGVEHDVVQDRIEAGTFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VTEEEYGIRVQANTPKLKPVTVKTLPHPGFPTDMQAQFTALMAVVNGESTMVETVFEN
                     RFQHLEEMRRMGLQSEILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTI
                     VNNLVHLDRGYYQFHEKLAKLGATISRSSEV"
     gene            26036..26224
                     /locus_tag="VCR92_000626"
     CDS             26036..26224
                     /locus_tag="VCR92_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEP4267714.1"
                     /translation="MTNGLKYVLEQMLLLLVIAALACLFLAIGLMIGYSFMGDGHSPW
                     HILSMDKWAELVNKFTGK"
     gene            26288..27125
                     /locus_tag="VCR92_000627"
                     /pseudo
     CDS             26288..27125
                     /locus_tag="VCR92_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062027.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
     gene            27408..28451
                     /gene="pheS"
                     /locus_tag="VCR92_000628"
     CDS             27408..28451
                     /gene="pheS"
                     /locus_tag="VCR92_000628"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEP4267715.1"
                     /translation="MDLQAQLEELKTKTLETLQSLTGNHTKELQDLRVAVLGKKGSLT
                     ELLKGLKDLSNDLRPVVGKQVNEVRDLLTKAFEEQAKIVEAAKIQAQLDAESIDVTLP
                     GRQMTLGHRHVLTQTSEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEEILLRTHTSPVQARTLDQHDFSKGPLKMVSPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKNISMGDLKGTLEMIIKKMFGEERSIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVDAKEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDQRFSEQFN"
     gene            28661..31066
                     /locus_tag="VCR92_000629"
     CDS             28661..31066
                     /locus_tag="VCR92_000629"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEP4267716.1"
                     /translation="MLVSYKWLKELVDIDVTPAALAEKMSATSIEVEGIEVPADGLSK
                     LVVGHVLSCEDVPETHLHLCQVDTGDETPRQIVCGAPNVKAGIKVIVAVPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLSDSIIPKEFSDGIQILPEEAVPGDAIFKYLDLDD
                     HIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPQKNLQESDKATSEAIEVAIASDN
                     VLTYASRVVENVKVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDK
                     FEDHKIVARAARQGESLVTLDGEKRDLTTEDLVITVADKPVALAGVMGGQATEIDANS
                     QTVVLEVAVFDGKSIRKTSGRLNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEG
                     QVLSGHVQAGQLPTEPVEVSTSLDYVNVRLGTELTFADIQRIFDQLGFGLTGDETSFT
                     VAVPRRRWDVSIPADLVEEIARIYGYDKLPTTLPEAGGTAAELTPTQALRRKVRGLAE
                     GLGLTEIISYALTTPEKAVEFAVAPSHLTELMWPMSVERSALRQNMVSGMLDTVAYNV
                     ARKQSNLALYEIGKIFEQEANPKEDLPNELNHFAFAICGLVAQKDFQTQAQAVDFYHA
                     KGILDTLFANLNLKVQYVPTKDLASMHPGRTALILLDEQVIGFVGQVHPGTAKAYSIP
                     ETYVAELDMAALEAALPSDQTFAEITKFPAMTRDVALLLDREVSHQAIVTAIESAGVK
                     RLTKIKLFDVYEGVTIQAGKKSMAYSLTFQNPNDNLTDEEVAKYMEKITKALTEQVGA
                     EVR"
     gene            31176..31553
                     /locus_tag="VCR92_000630"
     CDS             31176..31553
                     /locus_tag="VCR92_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HEP4267717.1"
                     /translation="MYQTKITGNRLYHTVSKGYGDSVTLFGKTDQGETPMSLLVIALS
                     SCVTMCVQGFYHRQFQQDTLAVSVEASYEEEVFELLVRIDDVLDDKKKADLLAYIGTY
                     CRVKQLLKPEVMVTITLEGLSHV"
     gene            31546..31932
                     /locus_tag="VCR92_000631"
     CDS             31546..31932
                     /locus_tag="VCR92_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HEP4267718.1"
                     /translation="MSDAGLKTYQKQWAYQKYWVMAHSQQHYNALRELFKGNQWSEEK
                     VLTFHCLIEEAQAIPPTVKSLRTAYQHVWGYFKKVASQEEKDHFKDLDAQLETKSEEM
                     LCFLQEMTAHYQPSYLLSCRLITKGP"
     gene            32005..33081
                     /locus_tag="VCR92_000632"
     CDS             32005..33081
                     /locus_tag="VCR92_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4267719.1"
                     /translation="MFLALNEMKQSKLRYGLIAGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDLWKADSILLAKDADATLTLSQVSRAQENQITADKVAPLAQLNTVAWSVKNPKDA
                     DKVKVSLFGIDSNSFIRPNIVKGRLFKTNKEVVLDQSLAKEEAFAIGKDFYTSSSSQA
                     LTIVGYTQNARFSVAPVVYMNLEAFETLKYGEPLPKDKQVVNAFITKGSLTDYPKKDF
                     QKLDIKTFITKLPGYSAQLLTFGFMISFLVIISAIIIGIFMYILTIQKAPIFGIMKAQ
                     GISNKTITTAVLMQTFFLSFLGSGLGLLGTWLTSLLLPTVVPFQSNWFLYLAIFVSMI
                     CFALLGTLFSVFNIIRIDPLKAIG"
     gene            33091..33759
                     /locus_tag="VCR92_000633"
     CDS             33091..33759
                     /locus_tag="VCR92_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4267720.1"
                     /translation="MSVLTFKQVTKTFQDGHHEINALKATDFSIEAGEFVAIIGPSGS
                     GKSTFLTIAGGLQTPSSGQLIIDGTDYTHLSEKERSRLRFKSVGFILQASNLIPFLTV
                     QQQLELVDHLTGSKEKAKANQLFDDLGITGLKHQLPQELSGGERQRAAIARALYHDPA
                     LILADEPTASLDTEKAYEVVKLLAKESKEKNKAIIMVTHDDRMLKYCDKVYRMQDGEL
                     RQER"
     gene            complement(33864..34781)
                     /locus_tag="VCR92_000634"
     CDS             complement(33864..34781)
                     /locus_tag="VCR92_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HEP4267721.1"
                     /translation="MKTDDLRESQQVEDRRGQSSGSFGGGGLGGGLLLQLLFSRGGWK
                     TKLVILLLLLVMGGGGLSSVLGGKPSSTNNNAYQSSQVTRTNGDKASQEQVSFVSKVF
                     ASTEDYWTKTFREKGLTYHKPTLVLYTGATQTACGRGQASSGPFYCPGDQKVYLDISF
                     YNELSTKYGAKGDFAMAYVIAHEVGHHIQNELGIMDNYASARQGKSKAKANQLNVKLE
                     LQADYYAGAWANYVQGQGLLEKGDIEEAMAAAHAVGDDTLQEETYGRTVPDSFTHGTS
                     KQRQRWFDRGYQYGDFEHGDTFSIPYSKL"
     gene            34932..38147
                     /gene="rexB"
                     /locus_tag="VCR92_000635"
     CDS             34932..38147
                     /gene="rexB"
                     /locus_tag="VCR92_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEP4267722.1"
                     /translation="MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKER
                     EVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQHLDDTTLAMIFYRALMQLKPEDL
                     PSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQ
                     QDYNQDSPLQSFARAIKLGLLNNQLSKTVIVIDGFSRFSAEEDYLLSLLNNNCQEVII
                     GSYVSQKAYQKSFIKGNIYEASLHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFE
                     ATHDFSQVDWQLQKNDLDHFSLWQCHHQKEEIEHVAKSIRQKLYEGYRYKDILVLLGD
                     MDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKS
                     GLFGCFDDSDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQ
                     ELFKSQKQLGASLVDKLILFFKKIRLAENMQGLAQSQLEVEKNEEVWKRFTDILTSFH
                     HIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFVYAIGLT
                     QSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELV
                     LSVPTVINETFDDLSPYLKELISFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINR
                     QDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYRLSTKPLSKEVIEVCFPKGIP
                     LKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEP
                     FDNKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIKVIDQE
                     KNFHLDMGNEILVHGIIDRIDQLSDGSLGIVDYKSSANQFDIGTFYNGLSPQLVTYLA
                     ALKQIAPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKALTYKGIFSEVEKE
                     HLSTGAYQTKNALYSNDELETLLNYNKYLYLKAAKHIKKGHFLINPYTSDGKTVQGDQ
                     LKAITRFEADLDMAQARRLVTLPAKEKKECFLTLMRKESHL"
     gene            38108..41776
                     /gene="addA"
                     /locus_tag="VCR92_000636"
     CDS             38108..41776
                     /gene="addA"
                     /locus_tag="VCR92_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEP4267723.1"
                     /translation="MLFNINEKGEPLVISFAPFLSPEAIKHLQENERCSDQSQKRTAQ
                     QIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFTVKAATELRE
                     RIENKLYSQIAQTTDFQMKVYLTEQLQSLGQADIGTMDAFAQKVVSRYGYSIGISSQF
                     RIMQDKAEQDVLKQEVFSKLFSEFMNQKEAPVFRALVKNFSGNCKDTSAFRELVYTCY
                     SFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHDIELLLLAMQDTANQLRDVTDMEDY
                     GQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTGLIPSGNDVTV
                     SKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESA
                     FEFSDITHFAIKILEENTDIRQFYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFM
                     VGDIKQSIYRFRQADPQIFNQKFRDYQKKPEQGKVILLKENFRSQSEVLNVSNAVFSH
                     LMDESVGDVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSE
                     VTIVAKEIIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYSIPIVTDGGQQNYLKS
                     VEVMVMLDTLRTINNPRNDYALVALLRSPMFAFDEDDLARIALQKDNELDKDCLYDKI
                     QRAVIGRGAHPELIHDTLLGKLNIFLKTLKSWRRYAKLGSLYDLIWKIFNDRFYFDFV
                     ASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVAAPKQ
                     AVNLMTIHKSKGLQFPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGE
                     TTLNSVKVSMETLPYQLNKQELRLATLSEQMRLLYVAMTRAEKKVYFIGKASKSKSQD
                     ITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRL
                     QTPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKAAYEP
                     LLEPIGVDIIEKSSRSLSDFTLPHFSKKVKVEASHIGSALHQLMQVLPLSKPINQQTL
                     LDALREIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYREAPFAILKVDPISQ
                     EEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPV
                     TKRYLVLMGGGKPEIVEV"
     gene            41916..42728
                     /locus_tag="VCR92_000637"
     CDS             41916..42728
                     /locus_tag="VCR92_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEP4267724.1"
                     /translation="MNFKKIRFGFLLCLLLYPLAACNKSEQLNHYERIKKTRKLVVAV
                     SPDYAPFEFKALVNGKDTIVGADVQLAQAIADELDVDLELSPMSFDNVLSSLQTGKAD
                     LAISGISHTKERAKVYDFSIPYYQAENAIVMRASDAKVTKNISDLNGKKVAAQKGSIE
                     EGLVKIQLPKANLISLTAMGEAINELKAGQVYAVTLEAPVAAGFLAQHKDLALAPFSL
                     KTSDGDAKAVALPKNSGDLTKAVNKVIAKLDEQERYKSFIAETIALTKNTMK"
     gene            42869..43045
                     /locus_tag="VCR92_000638"
     CDS             42869..43045
                     /locus_tag="VCR92_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEP4267725.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(43173..43535)
                     /gene="mscL"
                     /locus_tag="VCR92_000639"
     CDS             complement(43173..43535)
                     /gene="mscL"
                     /locus_tag="VCR92_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEP4267726.1"
                     /translation="MVKELKAFLFRGNIIELAVAVIIGGAFGAIVTSFVNDIITPLIL
                     NPALKAANVENITQLSWNGVKYGSFLGAVINFLIIGTSLFFVVKAAEKAMPKKEKEAA
                     APTQEELLTEIRDLLAQK"
     gene            43665..45479
                     /gene="dnaG"
                     /locus_tag="VCR92_000640"
     CDS             43665..45479
                     /gene="dnaG"
                     /locus_tag="VCR92_000640"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEP4267727.1"
                     /translation="MGFLWGGDDLAIDKEMISQVKNSVNIVDVIGEVVKLSRSGRHYL
                     GLCPFHKEKTPSFNVVEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIIADKTGM
                     SLNIPPSQAVLASQHKHPNHALMTLHEDAAKFYHAVLMTTTIGQEARKYLYQRGLDDQ
                     LIEHFNIGLAPDESDYLYQALSKKYEEGQLVASGLFNLSDQSNTIYDAFRNRIMFPLS
                     DDRGHIIAFSGRIWTAADMEKRQAKYKNSRGTVLFNKSYELYHLDKARPVIAKTHEVF
                     LMEGFMDVIAAYRSGYENAVASMGTALTQEHVNHLKQVTKKVVLIYDGDDAGQHAIAK
                     SLELLKDFVVEIVRIPNKMDPDEFVQRHSPEAFADLLKQSRISSVEFFIDYLKPTNVD
                     NLQSQIVYVEKMAPLIAQSPSITAQHSYINKIADLLPNFDYFQVEQSVNALRIQDRQK
                     RQGQIAQAVSNLVTLPIPKSLTAIAKTESHLMHRLLHHDYLLNEFRHRDDFYFDTSTL
                     EILYQRLKQQGYITSYDLSEMSEEVNRAYYNVLEENLPKEVALGEIDDILSKRAKLLA
                     ERDLHKQGKKVRESSNKGDHQAALEVLEHFIAQKRKME"
     gene            45488..46597
                     /gene="rpoD"
                     /locus_tag="VCR92_000641"
     CDS             45488..46597
                     /gene="rpoD"
                     /locus_tag="VCR92_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEP4267728.1"
                     /translation="MTKQKEITTFNVQVAEFIRHHKKEGTAIDDDVTEKLVIPFALDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYIVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSEEEKELAVAVAKGDLMAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            46833..47171
                     /locus_tag="VCR92_000642"
     CDS             46833..47171
                     /locus_tag="VCR92_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEP4267729.1"
                     /translation="MSDTPKYTQDQVIAIKNRILEALETVIDPELGIDVVNLGLIYEI
                     RFNDNGYTEIDMTLTTMGCPLADLLTDYIHDALQDVPEVTKTEVKLVWYPAWTVDKMS
                     RYARIALGIR"
     gene            47309..48163
                     /gene="rfbD"
                     /locus_tag="VCR92_000643"
     CDS             47309..48163
                     /gene="rfbD"
                     /locus_tag="VCR92_000643"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEP4267730.1"
                     /translation="MILITGSNGQLGTELRYLLDERGVDYVAVDVAEMDITNEDKVEA
                     VFAQVKPTLVYHCAAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGATLVYISTD
                     YVFDGNKPVGQEWVETDRPDPKTEYGRTKRLGELAVERYAEHFYIIRTAWVFGNYGKN
                     FVFAMEQLAENHSRLTVVNDQHGRPTWTRTLAEFMCYLTENQKAFGYYHLSNDAKEDT
                     TWYDFAKEILKDKAVEVVPVDSSAFPAKAKRPLNSTMNLDKAKATGFVIPTWQEALKA
                     FYQQGLKK"
     gene            48282..49436
                     /locus_tag="VCR92_000644"
     CDS             48282..49436
                     /locus_tag="VCR92_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEP4267731.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELISHQSSKNIRYHVACLSD
                     TKHKVHFDYKGADCFYLNPPKLGPARVIAYDMMAITYALSYSDQHQIQNPIFYVLGNT
                     VGAFIAPFVKQIHNRGGRFFINPDGLEWKRSKWSKPVQAYLKFSEKQMTRQADLVISD
                     NIGIDRYLKQVYPWSKTCFIAYGTQTQPSRLTTADSKVRAYFQTFDIREKDYYLILGR
                     FVPENNYETAIKEFMASSTKRDLVIICNHEDNAYFKQLLAETECDKDPRIKFVGTLYD
                     KELLAYIREQAYAYIHGHEVGGTNPGLLEALAHTNLNLVLGVDFNQSVAKSAALYWSK
                     QKGQLAELINQVDAGFDSDRLGKEAKAIIQEHYTWEKIVGEYEALFLNEH"
     gene            49426..50358
                     /locus_tag="VCR92_000645"
     CDS             49426..50358
                     /locus_tag="VCR92_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEP4267732.1"
                     /translation="MNINILLSTYNGERFLAEQIQSIQRQTVNDWTLLIRDDGSTDGT
                     QDIIRTFVKEDKRIQWINEGQTENLGVIKNFYTLLKHQKADVYFFSDQDDIWLDNKLE
                     VTLLEAQKHEMTAPLLVYTDLKVVTQHLAICHDSMIKTQSGHANTSLLQELTENTVTG
                     GTMMITHALAEEWTTCDGLLMHDWYLALLASATGKLVYLDIPTELYRQHDANVLGART
                     WSKRMKNWLTPHHLVNKYWWLITSSQKQAQLLLDLPLKPNDHELVTAYVSLLDMPFTK
                     RLATLKRYGFRKNRIFHTFIFRSLVVTLFGYRRK"
     gene            50361..51164
                     /locus_tag="VCR92_000646"
     CDS             50361..51164
                     /locus_tag="VCR92_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4267733.1"
                     /translation="MNFLTKKNRILLREMVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRLGGNVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     IIVFSAVLGALINFLINLVVVLIFALINGVTISGYAYLSLFLFIELVVLVLGIALLLS
                     NVFVYYRDLAQVWEVLLQAGMYATPIIYPITFVLDSHPLAAKLLMLNPVAQMIQDFRY
                     LLIDRANVTIWQMSTNWFYVVIPYLVPFVILFIGIFVFKKNADRFAEII"
     gene            51164..52369
                     /locus_tag="VCR92_000647"
     CDS             51164..52369
                     /locus_tag="VCR92_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4267734.1"
                     /translation="MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQ
                     HVLKDINFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVDGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDSGKTTILVTHDMGAVKKYC
                     NRAVLIEDGLVKAYGEPFDVANQYSVDNTETAEDAMNAEKISVSDIAKDLKVSLISNP
                     RITPNDTITFEVSYEVLKDDFTYIAFSLTDIDRNIWVYNDNSLDYPTQGIGRKCISYQ
                     CQLSQLNDIKLKLEVTVRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLY
                     QRNGKWVFH"
     gene            52394..53401
                     /locus_tag="VCR92_000648"
     CDS             52394..53401
                     /locus_tag="VCR92_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEP4267735.1"
                     /translation="MYKVSIICTNYNKAPWISDALDSFLSQVTDFEVEIIVIDDASTD
                     DSREILKSYQKKSSGKIKLLFNETNIGITKTWIKACLYAKGKYIARCDGDDYWTDSFK
                     LQKQVDVLEASKRSRWCNTDFDFVNSQGDLLYANAFSSGHTPLTDTYEKVLALKGMTM
                     ASTWLVDADLMRQVNQKINVDTPDDTFDIQLELFQLTQLTYIKDSTTVYRMTTDSDSR
                     PTDTPKMIHRIQKLLDTQLNYLKKYNQVDTKEMSELLLQQDAKQEIRIHELSCFIQEL
                     QQTIVDKTKQQETREVELQNVIEEQKNQLSELRQQYHAIINSRQWKYTSKLIAFIRRK
                     K"
     gene            53398..55143
                     /locus_tag="VCR92_000649"
     CDS             53398..55143
                     /locus_tag="VCR92_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEP4267736.1"
                     /translation="MNRILLYVHFNKYNKISAHVYYQLEQMRSLFSKIVFISNSKVSH
                     EDLKRLKNHCLIDEFLQRKNKGFDFSAWHDGLITMGFDKLEEFDSLTIMNDTCFGPIW
                     EMGPYFENFEEKEAVDFWGITNNRGTKAFKEHVQSYFMTFKNQVIQNKVFQQFWQSII
                     EYENVQEVIQHYETQLTSILLNEGFSYQTVFDTRKAESSFMPHPDFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLNLIRETTNYPIDLIVSHMSQISLPDAKYLLSQKYLNCQ
                     RLAKQTCQKVAVHLHVFYVDLLDEFLTAFEDWNFHYDLFITTDSDIKRKEIKEILQRK
                     GKTADIRVTGNRGRDIYPMLLLKDKLSQYDYIGHFHTKKSKEADFWAGESWRKELIDM
                     LVKPADSILSVFETDDIGIIIADIPSFFRFNKIVNAWNEHLIAQEMMSLWRKMDVKKQ
                     IDFQAMDTFVMSYGTFVWFKYDALKSLFDLELTQNDIPSEPLPQNSILHAIERLFVYI
                     AWGNSYDFRIVKNPYELTPFIDNKLLNLREDEGAHTYVNFNQMGGIKGALKYIIVGPA
                     KAMKYIFLRLMEKLK"
     gene            55140..>57006
                     /locus_tag="VCR92_000650"
     CDS             55140..>57006
                     /locus_tag="VCR92_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEP4267737.1"
                     /translation="MIKDTFLKTNWLNISHHIILLVFGFYFSFYSLAKELVSSTAQPV
                     NYYAHLLNVSFVGYIISLIGLSYYLSRQVSRQLFLKTSFIVISYLIVSYWVQITQHLN
                     DKRFDIWSLTKNQFYQFQALPSLLIILVMATLIKILVAYFAIEKDRFGLLGYQGNTFS
                     VALILAVVPINDIHLLKLISSRFSELVRAGNSQIALLKISGLLIVLLVIFATIIYVVL
                     NALKHLKSNKPSFSVAATTSLFLALVFNYTFQYGVKGDEALLGYYVFPGATLFQIVAI
                     TLVALLAYVITNRYWPTTFFLLILGTIISVVNDLKESMRSEPLLVTDFVWLQELGLVT
                     SFVKKSVIVEMVVGLAICIVVAWYLHGRVLAGKLFMSPVKRASAVLGLFIVSCSMLIP
                     FSYEKEGKILSGLPIISALNNDNDINWLGFSTNARYKSLAYVWTRQVTKKIMEKPTNY
                     SQETIASIAQKYQKLAEDINKDRKNNIADQTVIYLLSESLSDPDRVSNVTVSHDVLPN
                     IKAIKNSTTAGLMQSDSYGGGTANMEFQTLTSLPFYNFSSSVSVLYSEVFPKMAKPHT
                     ISEFYQGKNRIAMHPASANNFNRKTVYSNLGFSKFLALSGSKDKFKNIENVGLLTS"
BASE COUNT        18165 a         9584 c        11465 g        17792 t
ORIGIN      
        1 ccaagaactt ggtaaaggca tcacagctat caataaagct taccgtccag gtgaaggtgt
       61 taaagcacgt aaagaagccg ctaaggctga tcttgaaaga gaagctgcta aggttcgtga
      121 agctatcgct aacgacccaa ccttaacaaa agctgataaa gctaaacaaa cagaagctgt
      181 tgctaaagct cttaaagctg ctatcgcagc ggttgataaa gcgacaacag ctgaaggcat
      241 taaccaagaa cttggtaaag gcatcacagc tatcaacaaa gcttaccgtc caggtgaagg
      301 tgttgaagca cataaagaag ctgctaaagc taatcttgaa aaagtagcta aagaaactaa
      361 agctcttatt tcaggagacc gttacttgag cgaaactgaa aaagcagtcc aaaaacaagc
      421 tgttgagcaa gctcttgcga aagcacttgg tcaagttgag gctgctaaga cagttgaagc
      481 tgttaagttg gcagaaaacc ttggtactgt agctatccgt tcagcatatg ttgctggttt
      541 agctaaagat actgatcaag caacagctgc tcttaacgaa gcgaaacaag ctgctattga
      601 agctcttaaa caagctgcgg cagaaacact tgctaagatt acaactgatg ctaaattgac
      661 tgaagctcaa aaagctgaac aatcagaaaa tgtatcatta gcgcttaaga cggctattgc
      721 gactgttcgt tcagcacaat ctattgcgtc tgtgaaagaa gcaatagata aaggtattac
      781 tgctatccgt gcagcctatg tgcctaataa ggcagtcgca aaatcatcgt cagcgaacca
      841 tcttccaaaa tcaggtgatg caaactcaat tgttcttgtt ggcttaggag ttatgtctct
      901 tcttttaggt atggtgcttt atagcaagaa aaaagaaagt aaagactaag aacctggctt
      961 tatccaaatt gctttctact atattttcaa accaaggtga ttttgaaatc accttggttt
     1021 tttggatcgt aagggcccaa gaacggagtg tattgaaaac atttcaaagt tcaattgaaa
     1081 aggcaacagt tttctgtaca gaatttataa ggcgtttttt gttcaaacga tgactcattt
     1141 agttatgggt gtttgataat taagattact gtgaaggtga tggtagttcc accagtggac
     1201 ttcctccttg gttttaaggg ttaattgttc tagtgaataa aaggtttctt ggtcgcgcag
     1261 tagggatcaa gcgagcagat aaaatgccta ttttaaatca gttcgagcga attttcgtgc
     1321 tacaagctca aaagaggcta ctaaagtatt agaatagttt atctctgagt gaagttcttg
     1381 ttataagaag atgatgttat cgtttgaaac gaccaaaaaa tctcctaact tttactaatt
     1441 tctacatgaa atctagtcca gtatttactc tacaaccttg attgattcgc ttaataaaga
     1501 catttctact tgattgttta cacatagtta ttgatagaat ctattataaa attcagtata
     1561 ttagatcata attgtttcta tattaatcaa ttattatttt ttttgtcatt tttgataata
     1621 ttaaaaagaa agggtttaca tattaatcat tttttactat aataaaagtg ataagaacta
     1681 gatagttgtt gtgttacaac agtacaattg agctagcctt gtccttgttg tgttaacttt
     1741 atttttaaaa taaggttaaa aataaacgac tcgcgttctt atcagttact tattagataa
     1801 ggaggtaaac cttatgttaa aatttacttc aaatatttta gctactagtg tagctgaaac
     1861 aactcaagtt gctcctggag gctgctgttg ctgctgtact acttgttgct tctcaattgc
     1921 tactggaagt ggtaattctc aaggtggtag cggaagttat acgccaggta aataatctat
     1981 ttagcatctc tatgtgatag tgatattaag gtaatgagtt tgctagcaac taagttatct
     2041 ttggtaactt ctgattatag atgaatggca tagaggtgtt agaaaacatg agacaaaagt
     2101 aatcttcttg atgctaacgt ctcaggtaat tagcaggtac tagatagtac ctgctaatta
     2161 ctatatgttt agtaaaatga gataggaaag atagttatgt cattttttac aaaggaacaa
     2221 caacctaaag agaattgtcc gccaataact gttgaaaaag caaggcaatt gtttgaattt
     2281 aatacaaacc acttgtcctt atcggattac catcatcaaa cggtgctaaa aacgtcaaag
     2341 cagctagttg ctcaacattt aatgcctaat gcaaccgata atcttagtca acattttttg
     2401 atgaactata aagctaataa taattattta ggcttccaag ctagtattgt cgactttttt
     2461 acagattctg ccgttgctaa tttttcaagt agttacgttt atgaaagtca ggaaaagata
     2521 attcgtttac caaaacctac caagatatca actgctctgt cgacatgtat tataaaacga
     2581 agaagtcatc gtcaattttc agatagacaa atgcctcttc aagatttatc aaacattctt
     2641 tattatgcat gtggtgttag ttcacaagca tcaattagag atggagcatc agataagatt
     2701 acactcagaa actgtgcttc aggtggaggt ttatacccta ttcatttagt tttttatgct
     2761 agaaacatca gtaaattaat agatggtttc tatgaatatc taccctatca gcatgcacta
     2821 aggtgttatc ggcatagctc tgaggaaaac gttagagatt ttgcggaata cggtgctatt
     2881 aatgctgaaa attgtaatat tattattatt tatgtctacc attacatgaa aaatacacgt
     2941 aaatatggga atcaggcgac tgcctatgct tttattgaat caggagaaat agcccagaat
     3001 attcaattga ctgcaactgc cttaacttat ggaagtattg atattggtgg ttataataag
     3061 gaatatctcc aagaattatt agatttagat gggctaggag agcatgtgat tcacatgaca
     3121 ctcgtaggaa ctaaggagtc tcaatgaaat atcaacttaa tagtaatgtt cgtgtcgtga
     3181 catttcaaga tacattttgt tttagaaaag gaatctggga ttttaatgaa gccattctag
     3241 atttgacaca agaacctcaa aatttaaaga tagtttatca agaaatagtt tcacagttgg
     3301 ttaagggagt agccattgat actgaaactt atgaaaatac tttagaacct gagatgttcg
     3361 ctaatttaat ggaagtcatt tcaggcttgt attacaatga tatgctgatg cttgaggatg
     3421 actacaatct tgaagaaaat gtcatgaaaa ttttaatggg taatttccgt tttatggcgc
     3481 aagcaggtca tatggtaagc aatgctcctg ttttgtttat cagtgattcg acttatgtta
     3541 atgaatctgc tgagttgcta gctgaacaac tgcatttaca attgcaagtg gctagcgatg
     3601 acttaaaaat gttaattcag cagacagatg ttagttcgcg tttagatgct ttggagcatc
     3661 gccgtaacat gaattgttta tcagaagcct tgtgcgatta ccaaagtatt attatttgtc
     3721 aagaacgctt gaatattatg atgttgcgac acttgaatga agttagcgta gctatgaaaa
     3781 aacaattagt gattggtttt gtagatggac cattcttgca cacttgtact ttgaatcctc
     3841 ctcatagtgc tgactttgat agcttagaaa gaagagtttt ggcacgttta caagactcaa
     3901 ctctctatca acattttgct aatcagattt taccagcaac acaagatgtg agccaggcct
     3961 atttaccatt gttaaatgtt ttaatgaatt tagtcgttag cgaagctttc attattgctc
     4021 aaacaggtag ttctaaattt gagggacgtt tattaagcat ttacttaccg acgcttgaga
     4081 ttcaggtcca agatattttg aaaatgtcta attcacagac acaaggagct ttggcaaaat
     4141 taaaatatga ggatcagcag atatcaacac gtgagattgt taaaaaactc cttgacgagt
     4201 aacctataag gagaatctat tatgttatac tattatcctt cttttaatca tatttttgat
     4261 gaattaaaaa gtttaagtgg caatcgaaca ggtatcttaa atcaatctca agttccagtt
     4321 tgcaaccatc ctcacgatgt ttacttaaaa agtattactg gccaaatgcc agattatcat
     4381 aaacaattta taggtgagtt gagtcaagtt agttatcaca ttattggtta cggcagttac
     4441 tatgaagaag cacttatcaa gtatttagga gaaagtattg aacgctatgc tactgtaatt
     4501 gccggagact tactatcaga tcggattgtc tatgcttctt ataatgagtt aaaactgtta
     4561 cataaagtga tgcctttaga atacttgcaa gtgtttactc aagaacagat cgcattatct
     4621 tgtgacttgc aaatgatgat gtgcgataaa atggtaactg agaacgatgt attgggctgg
     4681 gttaaatgtc ccatgttctt tgaggacgca gagatgtatg ttccagctca aatgctttgt
     4741 gttgggtata aaacaaatga gactgtagga gaaagacgga taataccagg attttctacg
     4801 ggaacagctt ctcacaaaac gttagaagcg gctatgtgca acagtttgat tgaatacatc
     4861 cagatcgatt caatgatgct tagctggtat actaagaagc cttgccccaa gattattgtt
     4921 gatgatcctg atattgaagt gattttagaa gaagctagac tgggaaaaga cagtctatac
     4981 gacattattc ctattgatat gactgtagga gaagataatc ctctttatac gtttggaatc
     5041 attctcaaaa ataaatatga tgaagggcct tacctcttgt ttggagtgca ggctgggtta
     5101 gatcctaaac atgctttgct aagagggatc atggaagctt cagctattag ctatagttac
     5161 tactataatc ttttatatca aaaagcttcc cttgcaaata ttgaatgcga agaacctttg
     5221 tttttagatt tagatagtaa tgtcttctat tatgcacatc ccaaggacca agaccataaa
     5281 tggaaggcct ttgaaccttt gatttcagga gaagttctgt taagtgattt ggaagatcat
     5341 tctggtaaag ataaaaaaga agatttgaag actttattag cttatgctaa gaaagtcagt
     5401 cctaatgctg tctttttaga tattacacct cctgaagctc tagaaaaagg ctggtacgtc
     5461 acgcgagttc tgatgccaga acttcttgaa atgtgtatac cagcatttcc ttttgctaat
     5521 catccacgaa tgagacagtt tggaggtgta acaaatgcct ttgtccatcc aatgccttaa
     5581 tctttgtttt ttgttggtaa ctttttgtcc ttcaattcct atgcaagcta tttttggaaa
     5641 ggaagatagt ggttatgcat ttaatttaat tggttttcta agagcaactc tgatttatga
     5701 cattttggct ttggtaagta tttatgtttt gtcacctcaa ataaccttgt ctcttgaaag
     5761 tattgatagt aagacgttct ttatgggact tgtattttgc gtcttgatag tactgattga
     5821 actcgttttc ttacatggtt tacgttgttg gcaaaaaaag caatggcttc ctgcaacttt
     5881 ctcgtttgta ggaacgacaa atgattggtc taagattggc tatcctttat tactagcttt
     5941 atttgaagag acgatttatc gttttttgtg gtttaatata ttagcttttc aatggcattt
     6001 accaacaatt attgttttaa ttgtaactag tttttgctat gctttaaatc acttattgat
     6061 ggggaaatcc attttttatg ctaagttggt aacaggcatc atttatggta gtatttacat
     6121 gctgactagt caattgtggt tggttgtgat aatgcatgta ggagggaact tgctagttga
     6181 gtgtcttagc catcttcaaa caaaaaagaa gaagggggtg acatgatgct attggttttg
     6241 ctgtcgtttt taggtctaac tactctttgg ttgaccagtt atcgaagacg ttgtttggct
     6301 agatggcatc ttcaatggtt agtggcctta tcctatcaag attttttaga tgtcttactg
     6361 agtctgtttc aatttgtcat tattatactt gttttattct tttactcagc tactattaat
     6421 ctaggagagg ttctgacctt tttgacacaa actagctggc attggcagat tctttgttat
     6481 ttagtgttgt atcttatggc catcatagag atgacgcttt tagttttaat tcttatcttt
     6541 gatgttttgc tccagaaaga tagtcgattg ctctttaaaa aaataacttg gctgcctttt
     6601 agacaagata aaccagtctt aagtatactt ttactaggca tagctattct agtagacagt
     6661 ctcttttatt tgggcttgct tatattatta ggagaacagt cgctaacaag tttagcaacg
     6721 cttattttag gttatgggat agtcaaggct tgtcgctatt caggctggtt aaatgtacta
     6781 ttagcttttt gtcttttcac tatagttgga ctatgggcag ttacggcaac tttattatat
     6841 ggttggctag taggtgcgat gatattaacg gtgacttatt tgatgattag ttgcaaagag
     6901 tattagcaat attaaaaagg agtgatatat gagttttgta caattaacaa atgttgtcaa
     6961 gtcctacaaa aacggcaaga aagctgtcaa tgatgtttcc ttgtctattg aagcaggtaa
     7021 tatttatggt ctgttaggac caaatggtgc tggtaagtct accttgatta atcttatctt
     7081 aggcttgatc cctttgagtt ccggtaaaat tactgtttta gggcaatccc aaaagactat
     7141 tcgaaaaata agttcgcaga taggttatgt tcctcaagac attgctgttt atccagacct
     7201 aactgcttat gaaaatgtag aactatttgg gtcactttat ggcttaaagg gagctcagct
     7261 taaaaaacaa gttctaaaaa gtttagaatt tgtggggcta cactcccaag ctaagcagtt
     7321 tccaagtcaa ttctcaggag gaatgaagag acggttaaat atcgcttgtg cgctagttca
     7381 ttcacctaaa ttaatcattt ttgacgaacc gactgtaggg attgatcctc aatcacgtaa
     7441 tcatatttta gagtcgattc gtttgctaaa caaagaaggt gccacagtta tttatacgac
     7501 ccattacatg gaagaagtag aggctctttg tgattatatt tttattatgg atcatggtca
     7561 agttattgaa gaaggaccta aatttgaact ggaaaaacgt tacgttgcaa atctagcaaa
     7621 ccagattatt gtaactctaa cagattcacg tcatttggaa ctggcagata agcctgattg
     7681 gtctttgata gaagatggag aaaaactcat gttgaagatt gataatagtg atatgacatc
     7741 agttgttcat cagctcacac aggccaatat tacttttagc gagattagac ataaccattt
     7801 gaatttagaa gaaattttct tacacttaac aggtaagaag ttacgagatt agaggttact
     7861 atggttttat ttcatttaat caaaaaagaa agtttacaga tttttagaaa ccgaacagcc
     7921 ttattgatga tggtgatttt tccaattttg atgatcgtta ttttaagttt tgcctttaaa
     7981 tcaagtttta atactgcgac aacagtccct aaattgacca ttcgttacca attagagggt
     8041 gaaaaaacgg attaccagaa aaattttctt gcttttttaa aagttttaaa ccaaaaactt
     8101 catttagagg ctaaacctag taattctctt gaaaaagatc gacaaagggt cagtgaagga
     8161 gccttaacgg ctgttttaga agtgaagaag aatcagacca ttaaggttat tactaataat
     8221 attaatcagc aaaatgcaga tttgatcaat atgctagtaa aaaattatgt agataatgct
     8281 aaaacttatg actcgatagc agctctttat cctcaacaat taaatcatat cagaaagcga
     8341 agtgtggact atgttaaggt cagttcaata cagacaagta aaggaatgac atcagctgat
     8401 tattatgcta tttctatgtt taccatgatt actttttata gtatgatgtc tgcgatgaac
     8461 cttgttttgt cagatcgtca acaacggatt acaaatcgta ttcacttaac aggagtttct
     8521 ccaagtcttt tggtctttgg aaaattaata ggtgctatgt tagcaacaac tgttcaattg
     8581 agtcttttat acatttttac aaggtttgtt ttacgagtta attggggcac taatgagtgg
     8641 atgcttattg gtataacagc ctccttagtc tatctctctg tagctatagg tatcgggcta
     8701 ggcataagca ttaaaaatga ggctttttta acggttgcat ccaatactat tattcctata
     8761 ttcgcctttt taggaggcag ttacgttcca ttgacaacat tacacagctc tattattaat
     8821 caattgtcga atatatctcc tattaaatgg gttaatgata gtttgttcta tcttattttt
     8881 ggtggtcaat ataatccgat tcctgtaact ttgatcgtta atattagtat cggaacaatt
     8941 tttataatat tggcattgat aggtatgaga aagcaggtga cgacatgatt tgttttataa
     9001 aaactctatt tgttaagata aagcgcaaaa aaacaagtta tgtgacattc tttttaatgc
     9061 ctattttaac gacacttttg gctttatctt tgagtttttc aaataataat caggctaaaa
     9121 ttgggatatt agataaagat aatagtcaga tatctaaaca atttattgct caactaaagc
     9181 aaaacaaaaa gtacgacatt tttaccaaaa tcaaaaaaga gcatattgat cactaccttc
     9241 aagataaatc tctagaagcg gtattgacta ttgacaaagg attctcagat aaagtgttgc
     9301 aaggaaaatc tcaaaaactc aatatacgtt cgattgctaa tagcgaaatt acagagtggg
     9361 taaaggcaca gaccaattat ctattggaaa actataatat tataggggat gtggctctag
     9421 gtaacgaaga tacttttaat agaattctcc aaaaaaacca acagttaaat tatgatgtta
     9481 agcaagtaac tttgacagac cgatcacgta gcaaagcagt atcttccaca acgacaggat
     9541 ttttgcttat tctaatgtta ggtagtacga gcgtgattta cagtggtatt ttggcagata
     9601 aatctggtca gttataccat cgattaatgt tatcgaactt atctcgtttt cgctatatgt
     9661 tgagttacgt ctgtgtagga tttgttgctt ttacgattca aattgtcatt atgctgagtt
     9721 tgttaaaagt atttaatatt agtttttttg ttccgacatc acttcttttg attatttttt
     9781 tcctttttag tttattagcg ataggctttg gcctgctgat tggagctatc acacaaaatt
     9841 cccaacaaag tagccagtta gctaatctta ttgtaatgcc gacttcaatg ttggctggct
     9901 gtttatggcc attgtctatt acgccttctt atatgcaagc aattggtaag ttattaccac
     9961 aaaattgggt tttatcagcc atagctattt ttcaaagtgg agggacctta tctcaggctt
    10021 ggccatactt gttagctcta atgggaacag cactagcttt gattagtttt tcaagtttat
    10081 tattaaaacc taccaaacta taattagtct tttgttaaaa aatactttcc taattagcta
    10141 actaccaggt agccctttta ttggcttata tgcaataaaa gggttgcttt ttgcttatat
    10201 tttctctagt gcacttatct tttgttaaaa gcgattgcga tgttactgtt gttactgtgt
    10261 tttttagaga gcatattatc aaaagcgacc tctctagaaa gttcgttttt gttgacagat
    10321 tagttgtcaa agtattttaa aaaaacgttt tcaataaaca taaaaactaa tgttattaaa
    10381 aaaagttgtg aaaacgtatt tattttatgg aatgtttttg ttacaataag catgtatcga
    10441 atgctataaa gctgtcttgt tcgctatcag ggatgcttgt gatgttatgt cagatcaaac
    10501 aaatctttaa ttgggtgact taacagatta aaagaaaaga tctaatcgtg ttacttgata
    10561 gtataattaa tgcaaacaga aagtgtatcc caattcatag tctcaggtgg aggttaatat
    10621 tcaaaaataa aatcttgttg ttgtcttaaa ctaatcacat taaaaggaga tatcatgatt
    10681 aacaagaaat atataatacc tgtttcattg ttgacactag ctattacgct tactagtgtt
    10741 gaagaagtta cttcacgcca aaatttgact tatgccaatg aaatcgtaac acaaaggcca
    10801 aagagagaat ctgttattag tgataaatcg aattttcccg tcatatcacc ttacctagca
    10861 agtgtggatt ttggtgagag aaaaacatct ttgccaacac ctgataaagg agtaaaagta
    10921 actactgaac agtctattgc tcaagtaaga aaggggcctg aagaaagaac ctatactgtt
    10981 actggcaaga ttacgagtgt gatcaatggc tggggaggct atggctttta tattcaagat
    11041 agtgaaggta ttggacttta tgtttatcct caaaaagatt taggatacag taagggagat
    11101 attgttcaat taacaggtac acttactcgc tttaaaggtg atttacaact ccaacaggtg
    11161 actgcacaca aaaagttaga gttatctttt ccgacttctg ttaaagaagc agtaatatca
    11221 gaattagaaa caacaacacc ctcaacatta gttaagttat ctcacgtgac agttggagaa
    11281 ttatcaactg atcaatataa caacacatct ttccttgtaa gggatgatag tggtaaaagt
    11341 atagttgttc atatagatca tcgtacaggg gttaaagggg ctgatgttgt tactaaaata
    11401 agtcagggtg atttgattaa cctcacagcc atattgtcta ttgttgatgg tcagttacaa
    11461 ttaagaccgt tttctcttga acaattggaa gtggttaaaa aggtcacaag ctcaaatagt
    11521 gatgcttcat ctcgtaatat tgtgaaaata ggcgagattc aaggagctag tcatacgtcg
    11581 ccacttctca aaaaagcggt caccgtagaa caggttgttg tcacttattt agacgattcc
    11641 actcattttt atgttcaaga tcttaatggt gatggtgatt tagcgacttc agatggtatt
    11701 cgtgtttttg ctaaaaacgc taaggttcaa gtcggcgatg ttttgaccat ttcaggtgaa
    11761 gtggaagaat tctttggtcg tggttatgag gaacgtaagc agactgacct taccatcacc
    11821 caaattgtgg ctaaagcagt gatcaaaaca gggacagctc aagttccatc accgcttgtt
    11881 ttagggaaag atcgtatcgc gccagccaat attattgata atgatggctt gcgtgtgttt
    11941 gatccagaag aagacgctat tgattattgg gaatcaatgg aaggcatgtt agtggcggtt
    12001 gatgatgcta aaatccttgg tccaatgaaa aataaagaaa tttatgtctt acctggctct
    12061 agtacaagac cgttaaataa ttcaggtgga gtattacttc cagctaattc ttataacaca
    12121 gatgtgattc ctgttctttt caaaaaaggc aaacaaatta ttaaagcagg agactcttac
    12181 aaaggaagat tagctgggcc agtatcttat agctatggta attacaaggt ctttgttgat
    12241 gacagcaaaa acatgccatg tttaatggat ggtcatctaa aacctgaaaa aacaaacttg
    12301 caaaaagacc ttagcaagtt aagcattgct tcttacaata ttgaaaactt ctcagccaat
    12361 ccttcttcaa ctaaagatga gaaggtcaaa cggattgccg aatcctttat tcatgatctg
    12421 aatgctccag acattattgg attaattgaa gtccaagata ataatgggcc gactgatgat
    12481 gggacaacgg atgcgacaca aagcgcgcaa cgcctcattg atgctattaa aaaactaggt
    12541 ggcccaactt atcgttatgt tgatattgct ccagaaaata atgttgacgg aggtcaacca
    12601 ggtggtaata ttcgaacagg attcctttat caaccagagc gcgtcagcct ttctgataag
    12661 ccaaaaggcg gtgctcgtga tgctctaact tgggttaatg gagaattaaa ccttagtgtt
    12721 ggtcgaattg atccaactaa cgccgcttgg aaagatgttc gtaaatcgct agcagcagaa
    12781 tttatcttcc aaggtcgtaa agtcgttgtt gttgcaaatc atttgaactc taagcgtggg
    12841 gataatgctc tttatggtcg tgtgcaacca gtcactttta aatctgagca aagacgtcac
    12901 gtcttggcta atatgctagc acaatttgcg aaagaagggg caaaacacca agctaatatt
    12961 gtgatgctag gtgactttaa tgattttgaa ttcacaaaga cgattcaatt aatcgaagaa
    13021 ggtgatatgg ttaacttggt gaaccgacat gatatttcag atcggtattc ttattttcac
    13081 caaggcaata atcagaccct tgataatata ttagtttcac gccatttact tgatcactac
    13141 gaatttgaca tggttcatgt gaattcccca tttatggaag ctcacggacg cgcatcagat
    13201 catgatccat tgttacttca attatcattt tctaaagaaa atgataaggc agagtcttct
    13261 aaacaaagtg taaaagctaa aaaaacttca aaaggaaaac tgttgccaaa aacaggagat
    13321 agtcttgttt atgtgataac gctactagga acggctagtt tattagtgcc tattttatta
    13381 ttgactaaag gcaaaaagga atcatagcga tttgaagaat tggagttcat aaagagtcgt
    13441 taaaggcttg atatacttac gttagacctt aagctaaaat ggatgactat ataaaaacta
    13501 atattgataa caaaagaaga taacaataag acagctttac ttgctaaaga cttttgtcaa
    13561 gctaattgtt ttatggtaca atgtaaccgt tgctttgcaa cccttggtgc ttagttccct
    13621 ttcaccaagc atattagaaa cgtagatagc ttttgagagt tatccagacg ttaaaggaga
    13681 aaaaatgaca aaattgactg tacacgacta tgttcacatt gggctagtag ctgccttgta
    13741 tgttgtctta actattaccc cgcctttaaa tgcgatttct tatgggatgt atcaatttag
    13801 aatatctgaa atgatgaatt tcttagcttt ttatcatcgc aagtatatta ttgcggtgac
    13861 tcttggatgt atgattgcta acttttatag tttcggactg attgatgtct ttgtaggcgg
    13921 cggttcaact cttatttttg tgaccttagg tgttattttg tttagtaagt atcaaaaaga
    13981 ttatcttttt aatggcattt ttaataaagc ttttgtttac ttttctttct tttttgcaac
    14041 ttccatgttt actgtagcaa tcgaacttta cttctttgga gctccatttt tattaacatg
    14101 gtttacaact gcgttgggag aattagtatc tctgctcata ggatcactta ttattgataa
    14161 gttgtctcaa agaatttcct tttagtaatg catcatactc aaaagagttg ggtcaatacc
    14221 cttctctttt ttatgttgtt tgtaatgtta aaatcgttct agatagaaat atttaacact
    14281 ttagctaata gtaccatatg gagtggccaa cgattacttt tgatgctgtt atgatataga
    14341 aatagctcat ttgttatctt ttatgataaa ataaaagtat gaaaaaacgc ataaaagaat
    14401 taacagatct tcttaaccgt taccgttatg actattatac taaagatgcc ccatcagttt
    14461 ctgacagtga ctatgataag ctttatcgtg aactggtgac tttagagcag tcatatcccg
    14521 agtatgtctt gcaagatagc ccaacgcagc aggttggagg gactatttta aaggggtttg
    14581 aaaaatatcg acatcagtat ccgcttttta gtttgcagga tgctttttca cgtgaggagc
    14641 tggatgcttt tgataagcgc gtcaaggccg aatttccgaa tgccacctat ctagcagagt
    14701 taaaaattga tggtttatct atttccttga gttatgagaa tggcttctta caggttggag
    14761 caacacgggg tgatggcaat atcggtgaaa atatcacaga aaatattaaa aaaataaagg
    14821 atattcctca ccaattgagt gagcctttaa ccatcaccgt tcgaggagag gcttacatgt
    14881 ctcgtcagtc ctttaaagcg atcaatgaag cacgccaaga aaatggggag actgaatttg
    14941 ctaatcctag aaatgctgcc gctgggacac taaggcagct agatacggca gtggttgcta
    15001 agcgtcaact agccactttt ttgtatcaag aagctagtcc gacagctaga aatcaacaaa
    15061 atgaggtctt agcagaatta gcagatctag gtttttcagt aaatccgtat tatcaactca
    15121 catcgtctat ggatgagatt tggaatttta tcaaaactat tgaggcaaaa agagatcaat
    15181 tagcttatga catagatggc gttgttatta aagttaatag cctagccatg caagaagagc
    15241 tagggtttac ggttaaagct ccacgctggg ctattgctta caaatttcca gcagaagaaa
    15301 aagaggcaga aatcctttcg gttgactgga cagtgggacg aacaggcgtg gtcacaccta
    15361 cagcgaatct aactcctgtg caactagcgg ggacaaccgt gagtcgtgca accctacata
    15421 atgtggatta tattgccgaa aaagatatcc gtattggcga tacagtgatt gtatataagg
    15481 caggggacat tattcctgct gtcttaaatg tcgttatgag taagcggaac cagcaagaag
    15541 tcatgcttat tcctaaacta tgcccatctt gtggtagtga attagttcat tttgaagatg
    15601 aggttgcttt gcgttgtatt aatccgttgt gtcctagttt gattcagcga agtttggagc
    15661 attttgcaag tcgtgatgcc atgaacatta ctgggctggg accagctatt gtggaaaaac
    15721 tatttttagc ggggtttgtt catgatgttg ctgatattta ccagttgacc aaagaagatt
    15781 tcatgcaatt agatggcatc aaagaaaagt cagctgataa attgctcgct gcgattgagg
    15841 cttctaaatc aaattcagct gaaaaactgt tatttggtct aggaattcgt catattggct
    15901 ctaaggttag tcgcttaatt ttagaggtat acggagatat ttctgctctt ttaaccgcta
    15961 aagaagagga aatcgcaagg atagatggtc ttggctcaac gattgctcaa tcacttactc
    16021 aatactttga acaaaaaacg gctgcgattt tagtagacga gttaaagaca gcaggtgtca
    16081 acatgcatta ctcaggtcaa aaagttaata gtgacgcagc gctttttggt ctaactgttg
    16141 ttttaactgg caaattaaat cagctgaacc gaaatgaggc caaagataaa ttagaggcat
    16201 taggtgccaa agttactgga agtgtatcta agaaaacaga tttagttatt gcaggtagtg
    16261 acgctggttc taagctagaa aaagcaaaga gcttaggaat tcggattgaa gatgaagatt
    16321 ggctacgcca gctttaagtg aggtaatgtt atgaaaaaac aattgagagc acgtctcatt
    16381 tataatccaa cgtcaggaca agaacttatg agaaaaagtg ttcctgaagt tttagacata
    16441 ttagaagggt tcgggtatga aacatctgcc tttcaaacaa cagcccaaaa gaactctgct
    16501 ctaaatgaag caagaagagc ggcaaaggca ggttttgact tattgattgc tgctggaggt
    16561 gatggcacta ttaacgaagt ggtcaatgga attgctccct tgaaaaagcg ccctaaaatg
    16621 gccattattc caacaggtac cactaatgat tttgctagag cgttaaaagt accaagagga
    16681 aatccgagcc aagcagcaaa acttatcgga aaaaatcaga ctatccagat ggatattggt
    16741 agagctaaga aagatactta tttcatcaat attgctgcag caggaagttt gacggaatta
    16801 acttacagtg taccaagtca gttaaaaacg atgtttggat acttggctta tcttgctaaa
    16861 ggagtagaac tgctcccaag agttagcaat gtgcctgtta aaattacgca tgacaaaggc
    16921 gtctttgaag gtcaagtttc tatgattttt gcagctatta ccaattctgt tgggggattt
    16981 gaaatgattg ctcctgatgc aaaactagat gacggtatgt ttacgctcat tttaataaag
    17041 acagcaaatc tttttgaaat tgtacatctt ttgcgtttga ttttggatgg tggtaagcat
    17101 attacagatc gtcgtgtcga atacattaag accagtaaaa tagtcattga accccaatgt
    17161 ggtaagcgaa tgatgattaa tttagatggc gagtacggag gagatgctcc aattacatta
    17221 gagaacctaa aaaatcatat cacttttttt gcagatactg atttgatttc tgatgacgct
    17281 ttagtcttag atcaggacga attggaaatt gaggaaatcg taaagaaatt tgctcatgaa
    17341 gtagaagact tagaacaaga attagaagaa taatacaata gttattagct actgacagtt
    17401 tagtcaaatg cactactatt agaatctaag atttttaaat taattgaggt agtgtttttt
    17461 gatgtgctca aagagtcaat ttattcatat gaggggccca tttgaggtct ctcttttttg
    17521 atcatatgca agaaaatgcc atgttttagg gatgttatta tacccttttt ggaatcttgt
    17581 tgcctttttg ttataataag agtgtaattc tatttttaaa aagatcttaa caaagacaga
    17641 ctcgtttatc aaaaaggtta gtattagtct aagaaagcgt actcagtcta aagaaatctg
    17701 ttgacattct taattttaag gaatagaata gcaaagtaaa aaaaatttaa aggagtattc
    17761 tactatgaat cctattttcg cattggcttt ggcctgtttt ggtgtttctc ttgccgaagg
    17821 tttcttgatg gcaaatcttt ttaaagcagc atctcgccaa ccagaaatca ttggtcaatt
    17881 acgttcatta atgatcttgg gtgttgcctt tatcgaaggt actttctttg ttacccttgt
    17941 tatggccttc attcttaaat aacagcctat ttgataatag aaaaggaggg tgttagatgg
    18001 aagaagctaa aatacccatg ctaaagcttg gtccaataac ctttaatttg accctacttg
    18061 ctgtttgtat tgtcacaatt gctgttatct ttgcctttgt tttttgggca agtcgccaaa
    18121 tgaaattgaa accagaaggg aagcaaactg ctttagaata tttaatcagt tttgtggatg
    18181 gtattggaga agagcactta gatcataatc tacaaaaatc ttattcgctg ttactcttta
    18241 ccatttttct ctttgtggct gtcgctaata atttagggtt atttactaag ttagagacag
    18301 ttaatggcta taacctatgg acctcgccaa cagccaatct ggcttttgac cttgctctat
    18361 ctctttttat taccttaatg gtacacattg aaggggttag acgtcgtggc ttggttgccc
    18421 atttgaaacg tttggctaca ccgtggccaa tgactccgat gaatttatta gaagagttca
    18481 caaatttctt atcacttgcc attaggttat tcggtaatat ctttgccggg gaagttgtta
    18541 caggtttgat tgttcaactg gccaattatc gagtttattg gtggccgatc gctttcctag
    18601 tcaatatggc gtggacagcc ttttcagtct ttatttcctg catacaggct tttgttttca
    18661 caaaactgac agcgacctat ctaggaaaga aagttaatga atcagaagaa taaggaagga
    18721 gaacaaacga atgtcaatca catttggtga actcgttggg aattttattc tagtaacagg
    18781 ttctgtaatc gtcttgttac tcttgatcaa aaaattcgct tggggtgcaa ttgaatcgat
    18841 tttacagaca cgctcacaac aaatctctcg agatattgat caggctgagc aatcacgttt
    18901 aagtgctcaa cagttagagg caaaaagtca agctaaccta gatgctagtc gttcacaagc
    18961 aagtaaaatc attagtgatg ccaaagaaat tggtcaatta caaggtgata aattggtggc
    19021 agaagctact gatgaagcaa aacgcttgaa agaaaaagcg ttgacagata ttgaacaaag
    19081 caaatcagac gctatttcag cagtcaaaac agaaatgtct gatttaacgg ttcttttagc
    19141 ggaaaaaatt atgggagcca atcttgataa gacggcgcaa agccagctta ttgacagtta
    19201 tcttgatgac ttaggagaag cttaatgacc aaaaaagaac aggctcttat cgagcaatat
    19261 gcaaaaagcc ttgttgaggt agcaagtgaa catcattctc ttgatgcctt acaagctgat
    19321 gtgcttgcga ttttagagac gtttgtaaca actaatcttg atcaaagtct atcaagtcta
    19381 gctgttccgc atgctgaaaa aataaaattg ctaaccttat taaagggaaa taattctgtt
    19441 tatatgaata atttcttgaa tctcatttta caaaacgaac gtgaagctta tttgtatcaa
    19501 atgcttcaga ctgttttaaa tgaaattgca atagtttcaa atcagtatga tgtgactgtt
    19561 acctcatcac tacctttgac tgaggagcaa aaaagccgtg ttcgagcagt tgttgcaaag
    19621 aaatttgctg taacagcggg tcgtttaatt gaaaaagtag atccttcgct tattggagga
    19681 tttattatca gcgtcaataa taaagtaatt gataccagta ttcgtcgtca attgcaagca
    19741 tttaaaatga atttaaaata gaaagtggtg tgacttttgg caattaatgc acaagaaatt
    19801 agcgctttaa ttaaaaagca aattgagaac ttccagccaa atttcgatgt cacagaaact
    19861 gggatcgtta cctatattgg tgacggtatt gcacgtgccc gtggattaga taatgccatg
    19921 agtggtgaac ttcttgaatt tgaaaatggt gcctatggga tggctcaaaa ccttgagtca
    19981 aatgatgtag gtattattat tcttggtgat ttttcagcaa tccgtgaagg agatgtggtt
    20041 aagcgcaccg gtaaaatcat ggaagtacca gttggtgaag ctctcattgg acgtgtggta
    20101 aacccacttg gacaaccagt tgatggcttg ggagatattg aaacaactgg ctttagacca
    20161 gtcgaaacgc cagctcctgg tgttatgcag cgtaaatccg tttctgaacc cttacaaact
    20221 ggattaaaag caattgatgc tttggttcca attggtcgtg ggcaacgtga gttgattatc
    20281 ggagaccgtc aaacaggaaa aacatccgta gctattgatg cgattttgaa ccaaaaaggt
    20341 caagacatga tttgtatcta tgtggctatt ggtcaaaaag aatcaaccgt tcgtacacaa
    20401 gttgaaaccc ttcgccgtta cggtgccttg gattatacta ttgttgtgac agcgtcagcc
    20461 tcacaaccat caccattgct cttcatcgct ccttatgcgg gtgttgccat ggctgaagaa
    20521 tttatgtacc aaggcaagca tgtcttgatt gtctatgatg atttatcaaa acaagcggtg
    20581 gcttatcgtg aattgtctct cttgcttcgt cgtccaccag gtcgtgaagc ttacccaggg
    20641 gatgttttct acttgcatag ccgtcttttg gaacgctctg caaaagtttc tgatgactta
    20701 ggtggaggtt ctatcacagc tctaccattt atcgaaacac aggccggaga tatctctgca
    20761 tatattgcga ctaacgttat ttcgattaca gacggacaaa tcttcttgca agagaacctc
    20821 tttaattcag gaattcgtcc agcgattgat gcaggatcat ctgtctcacg tgtaggtggt
    20881 tcagctcaaa ttaaagcgat gaaaaaggtt gctggtactc ttcgtttgga tttggcttcc
    20941 tatcgtgaat tagaagcctt tacccaattt ggttcggacc ttgatgctgc aacacaagca
    21001 aaacttaatc gtggtcgccg tacggttgaa atcttgaagc aaccattgca taaaccgtta
    21061 cctgttgaaa agcaagtcgt tattctttat gcccttactc atggtttctt agatgatgtt
    21121 cctgtagatg atattttggc ttttgaagaa gctctttacg actactttga cgttcattac
    21181 aatgatttat ttgaaactat ccgtaccaca aaagaccttc ctgaagaagc tgcccttgat
    21241 gccgctatta aagcgtttaa agaacactca aactttaagt catagaggga ggatactagt
    21301 atggcaggct ctctaagtga aattaaagct aaaattattt caactgagaa aacaagtaaa
    21361 atcactagtg ccatgcgtat ggtttcttct gcaaaacttg ttaaatctga gcaagcagct
    21421 cgtgattttc aaatttacgc ctcaaaaatt cgccagatta ctacagattt attgaaatca
    21481 gaattaacca taggatctga taatccgatg ttggtgtctc gtcctgtcaa aaaaacaggc
    21541 tatattgtca tcacgtctga taaaggactt gttggaggtt acaattcaaa aatcttgaaa
    21601 tctgttatgg atatgattac agagtaccat gctgatggtg actatgaaat catttctatt
    21661 ggtagtgttg gttcagactt cttcaaagca agagggatga atgtggcttt tgaacttcgt
    21721 ggacttgcgg atcaaccaag ttttgaacaa gtgagacaaa tcatttcaca atccgttgac
    21781 atgtttgtca atgagatttt tgatgagtta tatgtctgtt acaatcacca tgtgaatagc
    21841 ttaaccagcc aagtccgtgt tcaacagatg ttgccaattt ctgacttggt tgctgatgaa
    21901 gcagcagaag aaggtgttac tgggtttgaa ttggaaccta atcgtcatga tattttagat
    21961 caattgttac ctcaattcac agaaagttta atttatgggg ctatcattga tgctaaaacg
    22021 gctgaacatg cagcaggtat gactgccatg cagacagcga cagataacgc taagaatgtc
    22081 attaacgatt tgaccatcca atataaccga gctcgtcaag cagcaattac acaagaaatt
    22141 actgaaattg ttgcaggagc aaatgcacta gaataaaaaa taacgctgac tagcgattag
    22201 gttattgtca gcattcaatt ttatcaatcg agatgaaatg acttatggga cttttctatt
    22261 gaaagactgc tcttttcagt ataaaagaag ttagcaagac taactaagcc ctgactatcg
    22321 aatataagga gaaatgaatg agctcaggca aaattgctca ggttgttggt ccagtagtag
    22381 acgttatgtt tgcgagtggg gacaaacttc cagagattaa taatgcattg attgtttata
    22441 aagatagtga taaaaagcaa aaaatcgtcc ttgaagttgc tctggaactt ggtgacggta
    22501 tggtgcgaac aatcgctatg gaatcaactg atgggcttac acgtgggtta gaagttcttg
    22561 acactggtcg tgcgattagc gtaccagtag gtaaagaaac tttgggacgc gtctttaatg
    22621 tacttggaga aaccattgat ttggaagaac catttgcaga agatgttgac cgtcagccga
    22681 tccataaaaa agcaccatcg tttgatgaat tatcaacatc atcagaaatt cttgaaactg
    22741 gtatcaaggt aattgacctt cttgcccctt accttaaagg tggtaaagtt ggacttttcg
    22801 gtggtgccgg agttggtaag actgtcctta tccaagaatt aatccacaat atcgcccaag
    22861 aacacggagg tatttcagta tttaccggtg ttggtgagcg aacacgtgaa ggaaatgacc
    22921 tttactggga aatgaaagaa tcaggcgtta ttgaaaaaac cgccatggtt tttggtcaga
    22981 tgaatgagcc gcctggggca cgtatgcgtg tagcccttac tggtttaacc attgctgagt
    23041 atttccgtga tgtagaaggc caagatgttt tgctctttat tgataatatc ttccgtttca
    23101 ctcaggcagg ttcagaagta tcagccctct taggccgtat gccttctgct gttggttacc
    23161 aaccaacact tgctactgaa atggggcaat tgcaagaacg gattacatca actcaaaaag
    23221 gttctgttac atctatccaa gcgatttatg taccagcaga tgattatact gaccctgcgc
    23281 cagcaacagc atttgctcac ctggattcaa caactaacct tgaacgtaaa ttgacacaaa
    23341 tggggattta tccagccgtt gatccattgg cttcaagttc acgggcttta tcacctgaga
    23401 ttgttggtga agagcactat gctgtggcaa cagaagttca acgtgtgctt caacgctacc
    23461 gtgaattaca agacatcatc gctattttgg ggatggatga attatcagat gaagaaaaaa
    23521 cattggttgg acgtgcgcgt cgtatccagt tcttcctctc acaaaatttt aacgttgctg
    23581 aacaatttac cggtcttcct ggttcttacg tgccagttgc tgagacagtt cgcggcttta
    23641 aagaaattct tgaaggaaaa tacgatgatc ttccagaaga cgcctttcgt tcagttggtc
    23701 caatcgagga tgtgattaaa aaagccgaaa aaatgggctt ttagtgaggt gatgccatga
    23761 cacaaatgac tgttcaagtg gtaacgccag atggaatcaa atatgatcac catgctaaat
    23821 gtatttcggt aacaacacca gatggggaaa tggggatttt acctaatcac atcaatttaa
    23881 ttgcaccttt gcaagtccat gaaatgaaaa ttcgccgagg tggtgaagat gaaaaagtgg
    23941 actggattgc tatcaatggt ggtattattg aaatcaaaga taatgtggtt accgttgtcg
    24001 ctgattctgc agaacgtgac cgtgatatcg atgtcagccg agcagagcga gcaaaactaa
    24061 gagcagaacg tgaaattgca caggctgaaa cgactcacaa cattgatgaa gttcgtcgtg
    24121 ccaaggttgc cttgcgccgc gctttgaatc gtatcaacgt tagtaaaaag taagtggtgt
    24181 tgataaaaga caaggataag taagaaaggt ttttaaccta ttattttgtt tgctgagtct
    24241 ttttaacatc agtttctgag agtttgacca tactaccttc tctaaacacg ttattattgt
    24301 tgagaggagt tatatggggg aactcttttt tgtatccacg ttgttagtag aaactcagta
    24361 atgacgctta atgtattttt aggctatcaa cttagtcaga gaagatgtca acttaattga
    24421 taagttggac ggatcaagat ggtatgttat aataatccta tggaattatt aatgaagatc
    24481 attgcctttt cgtgtcattt attttttatt ggccttagtt accaattact gattagtgtg
    24541 attgactgga caaaatttag tcattatcat ccagaaaatc ttggccggct acgacttttt
    24601 gtctttttat tagctactgc cctagggtat ttggtgagcc attgtatgct ggaattgctt
    24661 caaattagcc agacgctctt ttttgagttc cgctaatact ggaataaaag aagtatggta
    24721 taattttact acgactaaga gatagataag ggagaaaatt gtggataaaa taatcattga
    24781 aggtggtcaa acacgcttag aaggagaagt tgttattgag ggtgctaaaa acgcagttct
    24841 tcctttactg gcagcatcta ttttaccttc aaaaggaaaa acaattctta gaaatgttcc
    24901 tattctatct gatgttttta ccatgaataa cgtggtacgt ggtttagata ttcgtgttga
    24961 ttttaatgaa gcagctaacg aaatcacagt tgatgcctca ggacacattt tagatgaagc
    25021 cccttacgag tacgtgagcc aaatgcgtgc ctctattgtt gttttaggac caattttggc
    25081 acgtaatggc cacgcaaaag tatcaatgcc tggaggctgt acgattggca gtaggcctat
    25141 taatttgcac ttaaaaggat tagaggctat gggggcaacg attactcaaa aaggtggaga
    25201 tattaccgct caagcagatc gactgcaagg tgccatgatt tatatggact tcccatctgt
    25261 aggagctacc caaaacttga tgatggctgc cactttagct gatggtgtga ccactattga
    25321 aaatgctgct cgtgagcctg aaattgttga tttagctcaa tttttgaata aaatgggagc
    25381 tagaattcgt ggtgctggaa cagagacgtt aacgataaca ggcgtcacaa gtcttcatgg
    25441 ggtggagcac gatgtggttc aagaccgtat tgaagcaggt acttttatgg ttgcagcggc
    25501 gatgacttca ggcaatgttt tgattagaga tgctgtttgg gaacataatc gtccattgat
    25561 ttcaaaatta atggaaatgg gtgtttctgt aacagaagaa gaatatggta ttcgcgttca
    25621 agcaaacacg ccaaagctca aacctgtaac ggttaaaacc ttgcctcatc caggttttcc
    25681 aacagacatg caagctcaat ttacagcttt aatggcagtg gtcaatggag agtctactat
    25741 ggttgaaact gtctttgaaa atcgatttca acatctggaa gaaatgcgac gcatgggctt
    25801 acaatctgaa atccttaggg aaactgccat gattcatggt ggaagacaac tgcaaggtgc
    25861 tcctgtgatg tcaacagatt tacgtgccag tgctgccctt atcttgacag ggattgttgc
    25921 tcaaggagtg acaatagtta ataatttggt tcatttagat cgtggctact atcaatttca
    25981 tgaaaaatta gcaaagcttg gagctactat tagtcgtagc agtgaggtct agcttatgac
    26041 aaatggttta aaatatgtct tagaacaaat gttattactt ttagtaattg ctgccttggc
    26101 gtgtcttttt ttagccattg gacttatgat tggttatagt tttatgggag atggccatag
    26161 tccatggcat attttatcta tggataagtg ggcagagtta gtgaataaat ttactggaaa
    26221 gtaggccttg cctacttttt atagcatttg agaggaagta tgttaacaag gaaaaaaacg
    26281 aaaaaggatg cttaattcct tcttattgat tttgttagtg ttggggtcta acagccttgc
    26341 taagagtgat ttcatagcta gcactcaccc tatcaagcaa ctttatcaga ctcttgttgg
    26401 ggagaagaaa aaatcattac tcacacataa taatttgccc gctgatgttc ccacagaagc
    26461 tctggcggca tcggtattga caccatcaat caaaaagcaa ctaggtccag atgttcagtg
    26521 gaatggagca ggcgcctata ttatcaacag gaacaaaaca gatttaactg ctaaggtagc
    26581 cagtccgcct tatgccaaca atgaaaccaa atgggtgcaa gagcaaaagg ttcctactag
    26641 agctaatgcc ttacttacta agtcgacacg acagtatcaa aatcgctatc aaacgaacaa
    26701 tgcttatcgt acctttaagc cagcaggttg gcaccgattg caccacttaa aaggaagtta
    26761 tgatcacgcg gttgatagag ggcatttgct aggttatgct ttagttggtg gactgaaagg
    26821 ttttgatgct taccagtaat cctgataata ttgccactca actaagttgg gctaatcaag
    26881 taaataaacc ctactcgaca ggtcagaact actatgaagg tttagtacgt cgtgctttgg
    26941 ataaggggca tcgcgtccgc taccgtgtca ccctacttta tgatggtgat aatctactag
    27001 ccagcggtag ccatttggag gctaaatcct ctgatgacag cttgactttt aacgtgtttg
    27061 ttccaaatgt ccaaccagga ttgaccgttg actatcggac gggacaaata gctatcaatc
    27121 tctaagcgaa aagtcactga tttaagattg tcactaagca ctttttttga tagaatagaa
    27181 ctaattgaat aagtgtctat gagactagta ctaatagaga aattaacagg gagtgagggc
    27241 cgtgactgga agccttctta agggaactat taggaattca ctcagctaaa gacaattaat
    27301 taaggtctga taacatcaga taaaaacgga tggtaccgcg tgtcaacgct ccgcttatga
    27361 agtggagtag tggcacgctt ttttcatcgc taaaagaagg gaaaactatg gatttacaag
    27421 cacaattaga ggaattaaaa acaaaaacat tggagactct ccaatctttg acggggaatc
    27481 ataccaaaga actgcaagat ttgcgcgtgg ctgttcttgg gaaaaaggga tctttgacag
    27541 aattactaaa ggggctaaaa gacttgtcta atgacttgcg tcctgtggtt ggtaaacagg
    27601 tgaacgaagt tcgtgactta ttgacaaaag cctttgaaga acaggctaaa attgtagaag
    27661 ctgctaaaat tcaagcccag cttgatgctg aaagcattga tgtgacttta ccgggtcgtc
    27721 aaatgactct gggccaccgt catgtgttaa cacaaaccag tgaagaaatc gaagatattt
    27781 tcttaggaat gggttttcag attgttgatg gctttgaggt agaaaaagat tattacaact
    27841 ttgagcgcat gaatttgcca aaggatcacc ctgcccgtga catgcaagat acgttttata
    27901 tcacagaaga aatcttgtta cgaactcaca ccagtcctgt gcaggcccgt actcttgatc
    27961 aacatgattt ttcaaaaggg cctttaaaaa tggtttctcc aggtcgtgtt ttccgtcgtg
    28021 atactgatga cgctacccac tcacatcaat tccatcaaat tgaaggtttg gttgtgggca
    28081 aaaatatttc catgggagac ctcaaaggga ctcttgaaat gattatcaag aagatgttcg
    28141 gtgaagaacg tagcattcgt ttgcgcccgt catatttccc gttcacagaa ccatctgttg
    28201 aagtggatgt ttcttgcttt aaatgtggtg ggaaaggctg taatgtctgc aagaaaacag
    28261 gatggattga aattcttggt gctggtatgg ttcacccaag tgtcttggaa atgtcaggtg
    28321 ttgatgcaaa agagtattca ggctttgcct ttggtttagg tcaagagcgg attgccatgt
    28381 tgcgttatgg cattaatgac attcgtggtt tctatcaagg cgaccaacgt ttctctgaac
    28441 aatttaacta aaatgagtcg tttgaagact tctgtcagct attttatcta agattgagtg
    28501 aaagttgata ggtaatgata ataggttaat tgtctaaggg gaaagtccct ctcgcttcaa
    28561 cgtcataagg gttttgactt ggaacttaaa atacgaaagg aaatgactca aatcacggct
    28621 tgagagcttt ctctagccga gtgatttggg cactaaaatt atgttagtat cttataaatg
    28681 gttaaaagaa ttagtagata tcgatgtgac accagcagca cttgctgaga aaatgtcggc
    28741 aacgagtatc gaggtagaag gaattgaagt ccctgcagat ggtttatcaa aactggttgt
    28801 ggggcatgtg ctttcttgcg aagatgtgcc agagacacat ttgcatttgt gtcaggtaga
    28861 tacaggtgat gaaacgccac gtcaaattgt gtgtggcgca ccaaatgtga aagcagggat
    28921 taaggttatc gtggctgtgc caggtgctcg tattgcggat aactataaaa tcaaaaaagg
    28981 caaaatccgc ggcatggaat ctcttggcat gatttgttcc ttgcaagaac ttggtttgtc
    29041 agatagtatt attccaaaag aattttcaga tggtattcaa atcttgccag aggaggctgt
    29101 gccaggtgat gctattttta aatacctgga cttggacgat catatcattg aattgtccat
    29161 tacacctaac cgtgctgatg cgctttctat gcgaggtgtg gcacatgaag tcgcagctat
    29221 ttatggcaag tcagtatcat tcccccaaaa aaatctacaa gaatctgata aggcaacttc
    29281 agaagccatt gaagtggcca ttgcctctga taacgttcta acttacgcta gccgtgtcgt
    29341 tgaaaatgtc aaagttaagc caagtccaca atggttgcaa aaccttttaa tgaatgctgg
    29401 tattcgtcct attaataatg tggttgatgt gaccaactat gtgctcttgt attttggtca
    29461 acctatgcat gcttttgatt atgataaatt tgaagaccat aagattgtgg cgcgtgcggc
    29521 tcgtcaaggg gaaagtttag tcacacttga tggtgaaaaa cgggatttga ccactgagga
    29581 tcttgttatt accgtggctg acaaaccagt tgctttggca ggtgttatgg gtggtcaagc
    29641 cactgaaatt gatgccaact ctcagacggt tgttcttgaa gttgctgttt ttgatggcaa
    29701 atcgattcgt aaaaccagtg gtcgtttaaa ccttcgttcg gaatcctctt cacgttttga
    29761 aaaaggggtt aactatgcaa ctgttttaga agcgcttgac tttgcagcgg ctatgttaca
    29821 agaattagca gaaggtcaag tcttatcagg ccatgttcaa gctggacaat tgccaacaga
    29881 acctgttgaa gtctcaacta gccttgacta tgtgaatgtt cgtttaggaa cagaattaac
    29941 ttttgctgat attcaaagga tttttgacca acttggattt ggtctaacag gagatgaaac
    30001 aagcttcacg gtagctgttc ctcggcgtcg ttgggatgtt agtattccgg ctgatttggt
    30061 ggaagaaatt gcgcgtattt atggttatga taagttgcca acaaccttac cagaggcagg
    30121 aggaacggct gcagaattaa cgccaacaca ggctcttcgt cgtaaggtcc gtggtttagc
    30181 ggaaggattg ggcttgactg aaatcatttc gtatgccttg acaacaccag agaaagctgt
    30241 tgagtttgca gtggcaccaa gtcacctaac agaactcatg tggccaatgt ctgtggaacg
    30301 ttcagcgctt cgtcaaaata tggtttcagg gatgttagat acggtagctt ataatgtggc
    30361 tcgtaaacaa agtaacttgg ctctttatga aattggaaaa atctttgaac aagaagctaa
    30421 tccaaaagaa gaccttccta atgaattgaa ccattttgct tttgctattt gtggcttagt
    30481 ggcacaaaaa gatttccaaa cccaagctca ggcagtggat ttttaccatg ctaaaggtat
    30541 cttggatact ttatttgcaa accttaacct caaggttcaa tatgtgccaa ccaaagacct
    30601 agcaagcatg cacccaggac ggacagcgct tatcctatta gatgagcaag tgattggatt
    30661 tgttggtcaa gttcatccag gaacagcaaa ggcttatagt attccagaaa cctatgtggc
    30721 agaattggat atggctgctt tagaagcagc gttgccaagt gatcaaactt ttgcggaaat
    30781 cacaaaattc cctgctatga cacgtgatgt tgccttgtta cttgaccgtg aagtgagtca
    30841 tcaggccatt gtaacagcta ttgaatcagc aggtgtaaaa cgcttgacta agattaagct
    30901 ctttgacgtg tatgaaggag taactattca ggctggcaaa aaatcaatgg cttatagcct
    30961 tactttccaa aatccaaatg acaatttaac ggatgaagaa gttgccaaat acatggagaa
    31021 aatcaccaaa gcattgacag aacaagtcgg tgctgaagta cgctaagaaa aaaactgggc
    31081 ctctaaggct ccgttttttt ctgttataat agaggaaaaa agaactccag ttcaaatgat
    31141 tggagaaaaa catcagaagg tggaggaaaa tcagaatgta tcaaacaaaa ataacaggca
    31201 accgccttta ccacacggtt tcgaaaggct acggagatag tgtaacctta tttggaaaaa
    31261 ctgatcaagg ggaaacccct atgagtttac tggttattgc cttgtcttct tgtgtgacta
    31321 tgtgtgtgca gggtttttac catcgtcaat ttcagcaaga cacacttgct gtttctgttg
    31381 aggctagtta tgaggaagaa gtttttgaac tacttgttag gattgatgat gttttagatg
    31441 acaaaaagaa agctgatttg ttggcttaca ttggaactta ttgtcgtgtg aaacaactcc
    31501 tcaaacctga agttatggtg accattacgt tggaaggact gtctcatgtc tgatgctggt
    31561 ttgaaaactt accaaaaaca atgggcttat caaaagtatt gggtcatggc acactcacag
    31621 cagcattaca atgctttaag agaattgttt aaaggaaatc agtggtcaga agaaaaggtg
    31681 ttgacttttc attgtttgat tgaagaagcg caagccattc ctcccacagt aaaaagctta
    31741 cgaacagcat atcagcatgt ttgggggtat tttaaaaagg tagcgagtca ggaagaaaaa
    31801 gaccatttca aagatttgga tgctcagttg gaaactaaat ctgaggagat gctatgcttt
    31861 ttacaagaga tgacggctca ttatcagccc tcttatctgc tatcttgccg tttgattacc
    31921 aaaggtcctt aaatgctaaa cagaaaagta gggacttctg ggaagttatg ctaagctagt
    31981 gatataaaca agggggaatg agagatgttt ttagcgctta atgaaatgaa acaatccaaa
    32041 ttgcggtatg gtttgattgc tggtttgcta tgtttggttg cctatttgat gttctttttg
    32101 tcaggattgg cctttggttt gatgcaggag aaccgctcgg cggttgatct ttggaaagct
    32161 gacagtattt tactagccaa ggatgctgac gctaccttga ccttatcaca ggtgtccaga
    32221 gctcaagaaa atcaaataac agcagacaag gtagctcctc ttgctcaact caataccgtg
    32281 gcgtggtcag ttaaaaatcc taaggatgcc gacaaagtta aggttagcct tttcgggatt
    32341 gattctaata gctttattcg tcctaacatt gtaaaaggtc gattatttaa gactaacaaa
    32401 gaggttgttt tggatcaaag ccttgcaaaa gaggaagctt ttgcgattgg caaggacttt
    32461 tacacatcga gttcgagtca agcattaact atcgttggtt atactcaaaa tgctagattt
    32521 agtgttgcac cagtggttta tatgaatctg gaagcttttg aaacattaaa atatggagaa
    32581 ccactaccaa aagataagca agttgttaat gcttttatca ctaaaggaag tttaacagat
    32641 tatcctaaaa aagacttcca aaaattagat attaaaacct ttattactaa attacctggt
    32701 tatagcgctc aacttttaac gtttggcttt atgattagtt ttcttgtcat tatttcagct
    32761 attattattg gtatttttat gtatattttg actattcaaa aggcacctat ttttgggatt
    32821 atgaaagcgc aaggaatttc taacaaaacg attacgaccg ctgtgcttat gcagacattc
    32881 tttttgagtt ttttaggtag tggtttaggg ttgctaggta cttggctgac atcattatta
    32941 ttaccaacag tagttccttt tcaaagcaat tggtttttat atttggctat attcgttagt
    33001 atgatctgtt ttgctctatt aggcacctta ttttctgttt ttaacattat acgaattgat
    33061 cctttgaaag caattggata ggaggtagtg atgtcggttt taacatttaa acaagtgacc
    33121 aaaacatttc aagatggtca tcacgaaatc aacgcattaa aggcaactga cttttccatt
    33181 gaagctggag aatttgtggc tattattgga ccatcaggtt ctggaaaatc aacctttttg
    33241 accattgctg gtggcttaca gaccccaagt tctggtcagc taatcattga tggcactgat
    33301 tatacgcatt tatcagaaaa agagcgctca cgcttgcgct tcaagtccgt tggttttatc
    33361 ttacaagctt ccaatctgat acctttttta acagtccagc agcagttgga attggtcgat
    33421 catttgacag gaagcaaaga aaaagccaaa gccaatcagt tatttgacga tttaggcatt
    33481 acagggctaa aacatcagtt acctcaagaa ttgtccggcg gagaaaggca aagagcggcg
    33541 attgcccgtg ctctctacca tgatccagca ctgatattgg cagacgaacc tactgcaagt
    33601 ttggatactg aaaaagccta tgaagtggtc aaactgttag ctaaggaaag taaagaaaaa
    33661 aacaaggcca ttattatggt cactcatgat gatcggatgc taaaatattg tgacaaagtc
    33721 tatcggatgc aagatggaga gttacgtcaa gagagatagt agactggtaa gagtttatga
    33781 tattagaaga aaaaaaccaa acaagcacag cacttgtttg gtttttttct aagtgtgact
    33841 attatcaata cgtcaccatt tccctaaagc ttactatacg ggatgctaaa ggtatcacca
    33901 tgctcaaagt cgccatattg gtaacctcgg tcaaaccaac gttggcgttg cttagaagtg
    33961 ccatgtgtaa aactatcagg aacggttctg ccataggttt cttcttgcag agtatcatcc
    34021 ccaactgcgt gagctgctgc cattgcttcc tcaatatctc ctttttccaa aaggccttgc
    34081 ccttgaacat aattagccca ggcaccagca tagtaatcag cttgtaattc caacttgacg
    34141 ttgagctgat tggctttagc ctttgatttt ccttgtctag cgctagcgta attatccata
    34201 attcccaatt cattttggat gtggtggcca acttcatgag caatcacata ggccatagca
    34261 aaatcacctt ttgcgccgta cttggttgat agttcattat aaaaagaaat atctaaatac
    34321 actttttgat cgcctgggca ataaaaagga ccagaagagg cttgacccct gccacaagcg
    34381 gtttgagttg ctccagtata tagaactaat gttggtttat gataagttaa ccctttctca
    34441 cgaaatgtct tagtccaata gtcctcggta gaggcgaaga ccttactgac aaaagaaacc
    34501 tgttcttgac tagccttgtc accatttgta cgcgttactt ggcttgattg ataggcattg
    34561 ttgttggtag aagaaggctt gcctcctaaa acactagata ggccaccccc tcccataact
    34621 aggagaagga gaagaataac cagcttggtt ttccaacctc ctcgtgaaaa gagtaattga
    34681 agcaggagac cgccccctag gccgccgccc ccaaaagaac cagacgattg accacgtcta
    34741 tcttcaacct gttgactttc tctcaaatca tccgttttca taagtttctc ccatctattt
    34801 cttgatttta ttataaaata attctattag aattgctatt tttatgatga gattataact
    34861 aaaaatagga aaagcaatag gtatttgcta taatataaca agggtagatt cagtttgtat
    34921 aaaggagtca tatgaaatta atttacacag agatgagtta ctcgatgaca gagattttgg
    34981 tgaatgaagc acgaaaagct gctgaccaag gttatcgagt gttctatatt gctccaaatt
    35041 ctctttcatt tgaaaaggaa agagaagtct taaccttatt gcctgaacga gggacttttt
    35101 cgataatagt aacccggttc gttcaaatgt caaggtattt tacagttgag agctctcctt
    35161 ctaagcaaca tctagatgac acgactttgg ctatgatttt ttatcgggcc ttgatgcaat
    35221 taaaaccaga agatttgccg agttatggtc gtttgcaaaa taattcggtt tttattgaac
    35281 aactagttga gttatataag gaattaaaaa acgcacaatt aagcgtacat gatttaacag
    35341 gattagacca tcctcaaaaa caagaagatc ttattaaaat tattgagctt gcagagacga
    35401 tcatgattca gcaagattat aatcaagata gtcctctaca atcttttgca agagcaatta
    35461 agttaggact tttaaataac caactatcaa aaacagttat tgttattgat ggtttttcac
    35521 gtttttcagc tgaagaggat tatttattat cacttttaaa taacaactgt caagaggtca
    35581 tcattggcag ttatgtgagt caaaaagctt atcaaaaatc ttttattaag ggaaatatct
    35641 atgaggctag ccttcatttt ttgcaagatt tggctcaaaa ataccatatc aagccggtat
    35701 ttgcgacctc taatcaagtg tttaaaccag ccttttcacg gctaacacaa ttatttgaag
    35761 caactcatga tttttcacaa gtagactggc aactccaaaa gaatgatctt gatcacttta
    35821 gcctttggca atgtcatcat caaaaagagg aaattgaaca tgtagcaaaa tccattcggc
    35881 aaaagctata tgaaggttac cgttataagg atatcttagt gttgctagga gatatggatg
    35941 cttatcaatt acaaattggg cctatctttg ataagtttga aatcccctac tatttaggaa
    36001 aagcagagcc tatggctgcc catccattag tccaatttat agaatcgctc gaacgaagtc
    36061 agcgctataa ttggcgtcgt gaagacattt taaacatgtt aaaatcagga ctttttggtt
    36121 gttttgatga tagtgatatt gatcgctttg aggaatatac tcagtttgca gatattaaag
    36181 gatttactaa attttcaaag ccttttacca ttaactcttc taggcagtat cctcttgact
    36241 ttttaaatga aatgagacaa gacatcgttt tacctttgca agaattgttt aagagtcaaa
    36301 aacaacttgg tgcttcactt gttgacaaat taatactttt ttttaaaaag attagattag
    36361 ctgagaatat gcaaggttta gcacagtccc aattagaggt ggaaaaaaac gaagaagttt
    36421 ggaaaaggtt tacagatatt ttgacttctt ttcatcatat ctttggccaa gaaaaattac
    36481 ggctatcaga ttgccttgct ttaatcaaaa cgggaatgaa atcagctcag tatcgtgttg
    36541 ttccagcgac attagatgtt gtcactatta aatcttatga ccttgttcaa ccacattcaa
    36601 aacctttcgt ttatgcaatt ggtctaactc aatcacattt tcctaagcaa attcaccatt
    36661 caggactact ttctgatcaa gagcgtgcta gaattaatga aataagaaat tatcgtcatt
    36721 ttgatattgc tagtgccgaa aatagtaaaa aaaaccatca aactgcgtta tctctgttta
    36781 atgctgctac taaagagtta gttcttagtg ttccaacggt aatcaacgag acattcgatg
    36841 atctatctcc ttatcttaaa gaattaataa gctttgggct acctcttttg gataaaggca
    36901 aaaactatct atcttatgat aatagcgata ttggtaacta taaagctctc ttgtcacaaa
    36961 ttattgctat taaccgacaa gatcttatag aaatgtcaga tcaagataag atgttttgga
    37021 ctgttgtctt acgttatctc aggaaacagt taagaaagca acagctagag ctacctactt
    37081 cagattatcg tttatcaaca aagcctttgt ctaaagaagt tatcgaggta tgttttccaa
    37141 agggaatccc tttaaagcta tctgcaactg ctttaaccgt tttttataat aatcagtaca
    37201 actatttttt gaaatatgtt ttgaatttaa acaaaacaga atccattcat ccagattcca
    37261 gaattcatgg tcaatacttg catcgtgtct ttgagcggtt aatgaaagat cacacgcaag
    37321 aaccgtttga taataaatta aaacaagcaa tctaccatac caatcaagaa agtttttttc
    37381 agcaggttta ccaagataat gccgaggctg agtacagttt agctatacta gaagatattg
    37441 ttagatcaac agcacctatc ttgcaactta accaaaacat aaaggtcatt gatcaagaaa
    37501 agaactttca tctggatatg ggaaatgaga tattagtcca cgggatcatt gatcgtattg
    37561 accagctgag cgacggtagc ttgggcattg ttgactataa atcaagcgcg aatcaatttg
    37621 atattgggac cttttataat gggttgagtc cacaactagt gacttacctc gcagccttaa
    37681 aacagatcgc accgcacgat ataaaccaat tatttggggc tatgtacctt catttgcaag
    37741 atcctaaatt ggatctagta acatttaaac aaattgataa cacattagtg gagagtatct
    37801 ataaagcgtt gacctataaa ggtatttttt cagaagtcga aaaagagcat ctatctactg
    37861 gtgcttacca aaccaaaaat gctctttatt ccaatgacga attggaaaca cttttaaatt
    37921 ataacaagta cctctatctt aaagctgcta aacacattaa aaagggacat tttttgatta
    37981 atccttatac aagcgatggt aagacagttc aaggagatca attaaaagcc attacccgtt
    38041 ttgaagcaga tcttgacatg gcacaggcaa ggcgactagt gactctccct gctaaggaga
    38101 aaaaagagtg ctttttaaca ttaatgagaa aggagagcca cttgtgattt cttttgcccc
    38161 atttttaagc cccgaagcta ttaaacattt acaagaaaac gaaaggtgca gtgatcagtc
    38221 tcaaaaacgc acagctcaac aaattgaagc aatttatact agtggccaaa atatacttgt
    38281 atcagcttct gctggttcag gaaaaacctt tgtaatggtc gaacgcatac ttgataaaat
    38341 tttgagaggt gtttcaattg atcggctttt tatctcaacc tttactgtta aagcagctac
    38401 agaactgcgt gaacggattg aaaacaaatt atactcacaa attgctcaaa ctacagattt
    38461 tcaaatgaaa gtttatttaa cagaacaatt gcaatctctt ggtcaagctg atattggtac
    38521 tatggatgct tttgcacaga aagtagtaag tcgctatggt tatagcattg gcatttcatc
    38581 ccaatttcgt atcatgcagg ataaagcaga acaagatgtt ttaaagcaag aggtgtttag
    38641 caaactcttt agtgagttta tgaatcaaaa agaggcaccg gtgtttaggg ctcttgtgaa
    38701 aaatttttct ggtaactgta aagacacttc agcttttaga gagttagttt atacttgtta
    38761 ttcttttagc caatcgacag aaaatccaaa aatatggttg caagaaaatt ttctaagcgc
    38821 tgctaaaact taccaaaggc ttgaagatat cccggatcat gatattgaac tcttactttt
    38881 ggcaatgcaa gacactgcaa atcagctaag agatgtgact gatatggaag attatgggca
    38941 gctgactaag gcaggtagcc gatctgctaa atacactaaa cacttaacga tcatagaaaa
    39001 gttgtctgat tgggtgcgtg attttaaatg tttgtatgga aaagccggat tggatcggtt
    39061 gatcagagat gtgacaggcc ttataccatc tgggaatgat gttacagtct cgaaggtaaa
    39121 ataccctgtt tttaagacct tgcatcaaaa attaaaacaa tttaggcatt tagaaacaat
    39181 tttaatgtat cagaaagact gttttccctt attggaacag ttacaagatt ttgtgcttgc
    39241 gttttcagaa gcttatttag ctgtcaaaat acaagaaagt gcttttgaat tttcagatat
    39301 tacacacttt gcaatcaaaa ttttagagga aaatacggat attcgccaat tctatcagca
    39361 acactatcat gaggtgatgg ttgatgaata tcaagataac aatcatatgc aagagcgact
    39421 cctgacctta ctatcgaacg gtcataatcg ctttatggta ggagatatca aacaatcgat
    39481 ctatcgattt cggcaagccg atcctcagat ttttaatcaa aagtttagag actatcaaaa
    39541 aaaacctgag caggggaaag tgattttact caaagaaaac tttcgtagcc aatcagaggt
    39601 gttaaatgtc agcaatgctg tttttagtca cttaatggac gaatcagtag gagacgtctt
    39661 atacgatgag caacatcagt taatagcagg tagtcatgct caaacagtcc cctatctaga
    39721 ccgtcgtgct cagttattgc tatataatag cgataaagat gatggcaacg ccccttcaga
    39781 tagtgagggt atttcattta gtgaggttac aattgttgcc aaagaaatta ttaagcttca
    39841 caatgataag ggtgtccctt ttgaagacat tacgttactc gtttcttcaa gaacaagaaa
    39901 tgatatcatt tctcatacat tcaatcaata tagtattcct atagtaacag atggtgggca
    39961 gcaaaactat cttaaatctg ttgaagtgat ggttatgtta gatacattac gcaccattaa
    40021 taacccaaga aatgattatg cccttgtggc tttactgcgc tcaccgatgt ttgcctttga
    40081 tgaggatgat ttagcaagaa tagcacttca aaaagacaat gagctagata aagattgcct
    40141 atatgacaag atacaaaggg ctgtgattgg aagaggtgct catcctgaat tgattcacga
    40201 taccttgctt ggcaagttaa atattttttt aaagacgttg aaaagttggc gtcgatacgc
    40261 taagctaggg tcgttgtatg acttgatttg gaaaattttt aatgatcgtt tttattttga
    40321 ttttgtagct agtcaagcaa aagcagaaca agcacaagct aatctatacg cattagctct
    40381 acgtgctaat cagtttgaaa aatcgggcta taaagggcta taccgtttta ttaaaatgat
    40441 tgataaggta cttgagacgc aaaatgactt agcagatgtg gaagtggctg ctcctaaaca
    40501 agctgttaat ttaatgacca ttcacaagtc taaaggttta caatttccgt atgtatttat
    40561 ccttaattgt gacaagcgct tctcaatgac agatattcat aaatcattta ttctgaatcg
    40621 gcagcacggt atcggtatca agtaccttgc agatatcaaa ggtttacttg gtgaaacaac
    40681 actcaattct gttaaagtaa gcatggaaac cttaccttat caattgaaca aacaagagtt
    40741 gcgcttagca actttatcag aacaaatgcg cttattgtat gttgctatga cacgagctga
    40801 aaaaaaagtt tattttattg gtaaagctag taagagcaaa agtcaagata tcacagatcc
    40861 taaaaagtta ggcaaacttt tgccgctggc tttacgagaa cagttattga cattccaaga
    40921 ttggctatta gcaatagcag atatattttc aactgaagat ctttattttg atgttcgctt
    40981 tattgaagat agtgatttga cacaagagtc agtcggacga cttcaaacac cacagttatt
    41041 aaatccagat gatcttaaag ataatcgtca atcagaaaca attgcacggg ctttagatat
    41101 gttagaagca gtgtctcaat tgaatgccaa ttatgaagca gctattcatt tgccaacagt
    41161 tcgaacgcct agccaactta aggcagctta cgagccttta ttagaaccca ttggtgtaga
    41221 tattatagag aaatcttctc gatcgctatc tgattttact ttgccacatt tttcaaaaaa
    41281 agtaaaagtt gaagcaagtc atattggatc agctcttcat cagttgatgc aggtgctccc
    41341 tttgtcaaaa ccgataaatc aacaaacgct tttagacgct ttaagagaaa ttgatagtaa
    41401 cgaagaggta aaaacagctc ttgatctcaa aaaaatagag tcgttctttt gtgatacaag
    41461 cctaggccaa ttttttcaga cttaccaaaa acacttgtat cgagaagcac catttgctat
    41521 tttaaaagtt gaccctatta gtcaagaaga atatgtccta cgtggtatta tagatgccta
    41581 ctttttgttt gatgatcata ttgtattagt ggactataaa acagataaat acaagcagcc
    41641 cattgagtta aaaaagcgtt accaacaaca gttggagtta tatgcagaag ctctcactca
    41701 aacgtataaa cttcctgtga ctaagcgcta tcttgtttta atgggaggtg gaaagccaga
    41761 aattgtcgaa gtttaaggtt gttgtgacac aagggtattt tgcaaatgat aatagtatag
    41821 ttgaggattt tacgaaatgc ttgaaaagct attgaccttt gaataataat acaatataat
    41881 aagttttatt agtgacaaaa aggaataaat atactatgaa ttttaaaaaa ataagatttg
    41941 gttttttgct ttgcctccta ctttatcctt tagcagcttg taataagtct gaacaactta
    42001 atcactacga aagaattaaa aaaacaagaa aattagtcgt tgctgtaagc cctgattatg
    42061 ctccttttga atttaaagct ttagttaatg gaaaagatac tattgttgga gcagatgttc
    42121 aattagctca ggctattgct gatgaattag acgttgatct tgagctttca ccaatgagtt
    42181 ttgataatgt tttgtctagt ttacagactg gtaaagctga tcttgctatt tcaggaatct
    42241 cacatactaa agaaagagct aaagtatatg atttttcaat tccttactat caggcagaaa
    42301 acgctatagt gatgagagca tctgatgcta aagtgaccaa aaatattagt gacctaaacg
    42361 gtaagaaagt agccgctcaa aaaggtagta tcgaggaagg tttagttaaa atacaattac
    42421 caaaggccaa tctgatttct ttgactgcta tgggagaagc cattaatgaa ctaaaagcag
    42481 gacaagtcta tgcagttacc ttagaagcac ctgtagctgc tggtttttta gcccaacata
    42541 aggatctggc tttagcaccc tttagcttaa aaaccagtga tggagatgcc aaagcagtgg
    42601 cccttcctaa aaatagtggt gacttaacca aagccgttaa taaggttatt gctaagttag
    42661 atgagcaaga acggtacaag tcatttattg cagagacaat agcactaacg aaaaatacta
    42721 tgaagtaata aggttaataa aaactttatt agtatccgtt ggaaaagtgt ttagaataaa
    42781 caataaaaga ggtttgactt tttttaaaaa ataatgtaat ataattggga acgtgaaaat
    42841 gttacaatat cttgaggagg tgaaacacat gtcaaaaaca gtagtacgta agaatgaatc
    42901 tcttgacgat gctcttcgtc gcttcaaacg ttctgttact aaagctggta ctcttcaaga
    42961 atcacgtaaa cgtgaattct acgaaaaacc ttctgtaaaa cgtaaacgta aatcagaagc
    43021 agctcgcaaa cgtaaaaaat tctaatggta aaaaataaaa acagttctca caattagaac
    43081 tgtttttatt ttttatccag aagaagcaag ggagcttttt tgatatcaaa aaaagcagtt
    43141 agacatgcct aactacttta tcaaaaatcg ctttattttt gagccaacaa atcacggatt
    43201 tctgtcaata attcttcttg agtaggagct gcagcttctt tttctttttt aggcatagct
    43261 ttttcagcgg cttttacaac aaagaaaaga ctggtaccga tgataagaaa attaataacg
    43321 gctcctaaaa agctaccata tttaacacca ttccatgaca attgagtgat gttttcaaca
    43381 tttgcggcct tcagagctgg gtttaaaata agcggtgtga taatatcgtt cacaaaagaa
    43441 gtgacaatag caccaaaagc tcccccgatg ataactgcta cagcaagttc aataatgttt
    43501 cctctaaaca aaaatgcttt taattcttta accattaaat attccccctt ttaatatctc
    43561 taagttaagc atagcataat tagtaaacaa aatccaatgg aatcacttca gtttttaaat
    43621 ttacaaaaaa gagtttcggt ggtataataa aacgtaaaac tagaatggga tttttatggg
    43681 gaggtgacga tttggcaatt gacaaagaaa tgatttccca agtaaaaaat agcgttaata
    43741 ttgtcgatgt cattggagaa gtggtcaaac tttcccgatc agggcggcat tatctcgggc
    43801 tttgcccatt tcataaggaa aagacaccct ctttcaatgt tgttgaagac agacaatttt
    43861 ttcactgctt tggctgtgga aaatcagggg atgtttttaa atttattgag gaataccgcc
    43921 aagtcccctt cttagaaagt gttcagatta ttgccgataa gactggtatg tcgcttaata
    43981 taccgccaag tcaggcagta cttgctagcc aacacaagca ccctaatcac gctttgatga
    44041 cacttcatga ggatgctgct aaattttacc atgcagtttt gatgaccact accattggtc
    44101 aagaagctag gaagtacctt taccagagag gcttggatga ccaattaatt gagcatttca
    44161 atattggttt agccccagat gagtcagatt atctttatca agctctttct aaaaaatacg
    44221 aggaaggtca attggttgct tcaggattgt ttaacttgtc cgatcaatcc aataccattt
    44281 acgacgcctt tcgaaatcgt atcatgtttc ccttatcaga tgaccgaggg catattattg
    44341 ccttttcagg acgtatctgg acggcagctg atatggaaaa gagacaggcc aagtataaaa
    44401 attcaagagg aacagttctt tttaacaaat cttatgaatt gtatcatctg gacaaagcaa
    44461 ggcctgttat tgccaaaacc catgaagtgt ttctaatgga agggtttatg gacgtgattg
    44521 ccgcttaccg ttccggctat gaaaatgctg ttgcttcaat ggggacggca ttgactcaag
    44581 aacatgtcaa tcaccttaag caagtcacta aaaaagttgt tttgatttat gatggtgacg
    44641 atgctggaca acatgctatt gcaaaatcac tagaattgct taaagatttt gttgtcgaaa
    44701 ttgtcagaat ccccaataaa atggatcctg acgaatttgt acaacggcat tccccagaag
    44761 catttgcaga tttgcttaag cagtcacgga tcagtagtgt tgaatttttt attgattacc
    44821 taaaacctac taatgtagac aatctgcaat cacaaattgt ttatgtggag aaaatggcac
    44881 cattgattgc tcaatcacca tccatcacag ctcaacattc gtatattaac aagattgctg
    44941 atttgttgcc aaactttgac tattttcaag tagaacaatc agtaaatgca ttaaggattc
    45001 aagataggca aaagcgtcaa ggtcaaatag ctcaagccgt cagcaatctt gtgaccttac
    45061 caataccaaa aagtttgaca gctattgcta agacagaaag tcatctcatg catcggctct
    45121 tacatcatga ctatttatta aatgaatttc gacatcgtga tgatttttat tttgatacct
    45181 ctaccttaga aatactttat caacggctga agcaacaagg atacattaca tcttatgatt
    45241 tgtcagagat gtcagaggaa gttaaccgtg cttattacaa tgttttagaa gaaaaccttc
    45301 ccaaagaagt agctcttggt gagattgatg atattttatc caaacgtgcc aaacttttag
    45361 cagagcgcga tcttcacaaa caagggaaaa aagttagaga atctagtaac aaaggcgatc
    45421 atcaagcggc tctagaagta ctagaacatt ttattgcgca gaaacgaaaa atggaataga
    45481 ggaaattatg acaaaacaaa aagaaataac aacttttaac gttcaagttg cggagtttat
    45541 tcgccatcac aaaaaagaag gaacagcgat tgatgatgac gtgaccgaaa aacttgtcat
    45601 tccatttgct ttggatgctg atcagattga tgatttactt gagcggttaa cagatggtgg
    45661 tatctcgatt acggataaag aaggtaaccc atcatcaaaa tacattgttg aagaaccaaa
    45721 accagaagaa ttaactgatg aagaattaat tggtagtaat tcagctaaag taaacgaccc
    45781 tgtccgcatg tacctcaaag aaattggtgt ggtaccgctt ttaacaagtg aagaggaaaa
    45841 agaattggct gttgcagttg ccaagggaga tttaatggct aaacaacgtt tagcggaagc
    45901 aaaccttcgt cttgttgtct caattgcaaa acgttatgtt ggacgtggaa tgcaatttct
    45961 tgatttaatt caagaaggta acatgggact catgaaagct gttgataaat ttgattattc
    46021 aaaaggattc aaattctcaa cttatgcaac atggtggatt cgtcaagcta taacacgcgc
    46081 aattgcagat caagcacgta cgattcgtat ccctgttcat atggttgaaa cgattaataa
    46141 attagtccgt gaacaacgta accttcttca agaacttggt caagatccaa cgccagaaca
    46201 aatcgcagaa cgtatggaaa tgactccaga caaggttcgt gaaattctaa aaattgctca
    46261 agaacctgtt tctttagaaa caccaattgg ggaagaagat gatagtcact taggtgattt
    46321 tatcgaagat gaagttattg aaaatccagt agattatacg acgcgtgttg ttcttcgtga
    46381 gcaattggat gaagttttag atacgcttac tgaccgtgaa gagaacgttc ttcgcctacg
    46441 ctttggcctt gacgatggta aaatgcgtac gttagaggac gtaggtaaag tctttaatgt
    46501 tactcgtgag cgcattcgac agattgaagc taaagccctt agaaaacttc gccatcctag
    46561 tcgtagtaaa caattaagag actttataga ggactaaaat cgtccagtgg acgattttag
    46621 gtcgttcctt tgaaataaga aaggagcgaa aatcctaagt ggcacttatc agcggtacac
    46681 ctacaaatta gaaatcggac cgaatgtggt gggtattttt aaggttggac ttgatatctt
    46741 aaacaagccc agagggcaat tcctctaaat aggcaaagct ttagtggttt ttttacttat
    46801 ctacgacata ttcaaaaaat gaaaggaaag ccatgtctga tacaccaaaa tatacacaag
    46861 atcaggtgat agctatcaag aatagaattc ttgaagcttt agaaactgtt attgatcccg
    46921 agctaggtat tgatgttgtt aatctaggtt tgatttatga aattcggttc aatgataacg
    46981 gttatacaga gattgatatg acactcacaa caatgggttg tcctttggca gacttgttga
    47041 cagattacat ccatgatgcc ctgcaagatg tgccagaagt cactaagact gaggtcaaat
    47101 tagtctggta ccctgcttgg acggttgata aaatgagccg ctatgctagg attgcgctgg
    47161 gtattcgcta atcattgata gtaaagggat gaaatattcc cttttttgat gtagaataaa
    47221 aggaaataca ggtgaaagcc tttggttaat gttagagaac actaagatac tgagaaaagt
    47281 gttctaccta tggcaaaaag gagaactgat gattttaatt acaggaagca atggtcaatt
    47341 aggaacagaa cttcgatact tattagatga acgaggtgtt gattatgtag ccgttgatgt
    47401 cgcagaaatg gacatcacaa atgaagacaa agtcgaagct gtttttgcgc aggtcaagcc
    47461 aacattggtc tatcattgtg ctgcttatac ggcagttgat gcagcagaag acgaaggaaa
    47521 agccttgaat gaggctatta atgtaacagg ctcagaaaat attgccaagg cttgtggaaa
    47581 atatggggct acccttgttt acatttcaac agactacgta tttgatggca ataaaccagt
    47641 cggtcaagaa tgggtagaaa cagatcgtcc agaccctaag acagaatatg gccgtacaaa
    47701 acgtttagga gaactagctg ttgaacgata cgcagagcat ttttatatta tccgtactgc
    47761 ttgggtattt ggaaattatg gtaaaaactt tgtctttgcc atggagcagt tagcggaaaa
    47821 tcactcccgt ttgactgttg tcaatgacca acacggtcgg ccaacgtgga caagaacctt
    47881 ggcagaattc atgtgttatt tgacagagaa tcaaaaagcc tttggttact atcacttgtc
    47941 aaatgatgct aaggaagaca ccacttggta tgattttgcc aaagaaatct taaaagacaa
    48001 ggctgttgaa gtggtgccag ttgattcatc agctttccca gcaaaagcca aacgtccttt
    48061 aaattcaacc atgaatcttg ataaggcaaa agcaacaggg tttgttattc caacatggca
    48121 agaagccttg aaggcatttt accaacaagg actgaaaaag taagtattct aaaaagagtt
    48181 ggctttctaa ggccaactct ttttcatggg tttaaggtcg cattagcctt ctaattgtgg
    48241 tataatatca ctgattatat tttagaatgg ggtagtatgc aatgcaggat gtttttatca
    48301 ttggtagcag agggttacca gcgaaatacg gtggctttga aacctttgtc gaagagttga
    48361 ttagtcatca atcatctaaa aacattcgtt atcacgttgc ttgtttaagc gatacgaagc
    48421 ataaggttca ttttgattat aagggggcag attgctttta ccttaatccc ccaaaacttg
    48481 gtcctgctag agttattgct tatgatatga tggcaattac ctatgccctg tcttatagcg
    48541 accaacacca gattcagaac cctatttttt atgtgttggg caatactgta ggcgctttta
    48601 ttgcgccatt tgtgaagcag attcacaatc gaggtggacg cttttttatc aatccagacg
    48661 ggttagagtg gaaacggtct aaatggtcaa aaccagtgca ggcctacctg aagttttccg
    48721 aaaagcaaat gactagacag gctgatttgg tcatttcaga taatattggc attgaccgct
    48781 accttaaaca ggtttatcct tggtctaaaa catgttttat tgcttatgga acgcagacac
    48841 aaccttcacg tttgacaaca gcagatagca aggtcagagc ttattttcaa acctttgata
    48901 ttagagaaaa ggattactat ctcattttag gacgctttgt tcctgaaaat aattacgaaa
    48961 ctgctattaa agaatttatg gcttcctcaa ctaagcgtga tttagtgatt atttgtaatc
    49021 atgaagacaa tgcttacttt aagcaattac ttgctgagac agagtgtgat aaagacccac
    49081 gcattaaatt tgttggtacc ctttatgaca aagaactatt agcctacatt cgagaacagg
    49141 cttatgccta tatccatggt catgaggtag gagggactaa tccaggcctt ctagaagcac
    49201 tagcccatac caatcttaat ttggttttag gagttgattt taaccagtcg gtggctaagt
    49261 ctgctgcgct gtattggtcc aagcaaaaag ggcaattagc agagctgatt aaccaagttg
    49321 atgcaggttt tgatagtgat cgtctgggca aagaagccaa agctattatt caagaacatt
    49381 acacttggga aaaaattgta ggggagtacg aggctttatt tttaaatgaa cattaatatt
    49441 ttactatcca cctacaatgg agaacgcttc ttagcagaac aaattcaaag tatccaaagg
    49501 caaacagtta acgactggac cttattgatt agagatgatg gatcaactga tggcacccag
    49561 gatattattc gcacatttgt caaggaagac aaacgaattc agtggatcaa tgaggggcag
    49621 acagaaaatc tgggagttat taagaatttt tacaccctct taaagcacca aaaagcagat
    49681 gtctattttt tcagtgacca agatgatata tggttagaca ataaactgga agtgacctta
    49741 ttggaggctc aaaaacatga aatgacagct cctttattgg tttatacaga cctcaaagtg
    49801 gtaacccaac atttagctat ttgccatgac agtatgatta agacccaatc tggtcatgca
    49861 aacacaagcc tacttcaaga attaaccgaa aataccgtaa caggcggcac aatgatgatt
    49921 actcatgctc tggctgagga atggaccact tgtgacggtt tattgatgca tgactggtat
    49981 ttagctttac tagcttctgc tactgggaaa ttagtttacc ttgatattcc aacagaatta
    50041 taccgtcagc acgatgctaa cgtgttggga gctagaactt ggtctaaacg catgaaaaat
    50101 tggttaaccc cccatcattt agtcaacaaa tattggtggt tgattacttc aagccaaaaa
    50161 caggctcaat tactattaga tttaccatta aaaccaaatg accatgaatt ggtaacggcc
    50221 tatgtttctt tattggatat gccttttacc aaacgcttag ctaccttgaa aaggtacggt
    50281 tttagaaaaa atcgcatctt tcacaccttt atttttcgta gtttagttgt taccttattt
    50341 ggttacagga gaaagtaaga atgaattttt taacaaagaa aaaccgtatt ttactgagag
    50401 aaatggtaaa aacggatttt aaattacgct atcaagggag cgcaattggc tatctatggt
    50461 ctatcttaaa accgcttatg atgtttacga ttatgtactt ggtatttatt cgttttcttc
    50521 gcctgggtgg aaatgtacct cattttccag tagcgctttt attggcaaat gtcatctggt
    50581 cttttttttc agaagcaact agcatgggaa tggtatctat tgtatctcgg ggagacttgt
    50641 tgcgaaaatt gaacttttct aagcacatca ttgttttttc ggcagtgtta ggagctttaa
    50701 ttaattttct tattaatttg gttgttgttt taatttttgc gttgataaat ggtgtgacta
    50761 tatcagggta tgcttatctc tctctttttc tttttataga attagttgtt ttagtgcttg
    50821 gaattgcatt gttattgtcg aatgtctttg tttattatcg tgacttagct caagtctggg
    50881 aagtactatt acaagcaggt atgtatgcca ctccaatcat ttatccgatc acttttgttt
    50941 tagatagcca ccctttggcg gcaaagttgt tgatgctaaa tccagtagca caaatgattc
    51001 aagattttcg ttatttattg attgacagag ccaacgtaac gatttggcag atgtcaacca
    51061 attggtttta cgttgttatt ccatatttag taccatttgt tatattattt attggcatct
    51121 ttgtctttaa gaaaaatgcc gatagatttg cggagattat ttaatgatta atagagaaat
    51181 tgcagtaaaa gtacagcatg ttagtaaaac atttaaactg cctacagaag caactaaaag
    51241 ttttcgcacg actctggtta atcgcctaag agggattaaa ggatttactg aacaacatgt
    51301 gctaaaagat attaactttg atgtttataa aggcgatttt tttggaattg ttgggcgtaa
    51361 cggctcggga aaatcaacgc tccttaaaat tatttcccag atctatgttc cagaaaaagg
    51421 acaggttaca gtagatggga agatggtttc ttttatagag cttggagtgg gattcaatcc
    51481 agaattaaca ggacgagaaa acgtctatat gaacggcgcc atgctgggat ttaccaaaga
    51541 cgaagttgat gatatgtaca atgatattgt tgattttgca gagttgcatc attttatgaa
    51601 tcaaaaatta aaaaattatt cttctggcat gcaggtacgt ttagcatttt cagtggctat
    51661 taaagcccaa ggtgacgttc ttattttaga tgaggtgctt gctgtaggag atgaagcttt
    51721 tcagcgaaaa tgtaatgatt attttatgga aagaaaagac agtggtaaga cgactatttt
    51781 agtgacacat gatatgggag ctgttaagaa gtattgtaac cgtgcagttc ttattgaaga
    51841 tggtcttgtt aaagcatatg gagaaccatt tgatgttgct aatcagtata gtgtagataa
    51901 tacagagaca gctgaggatg caatgaatgc tgaaaaaata tctgtatctg atattgccaa
    51961 agatttgaaa gtgtcattaa tctcaaatcc aagaataaca ccaaatgaca caatcacatt
    52021 tgaagtttct tatgaagttt taaaagatga ttttacctac attgcctttt ctttaacgga
    52081 tattgataga aacatttggg tttacaacga caattcttta gattatccaa cacaaggtat
    52141 aggtagaaaa tgcatttcct accaatgtca actatctcaa cttaatgata taaaactaaa
    52201 attagaagta actgtccgag ataagaacgg tcagatgcta ctcttttcaa cagcagaaca
    52261 atcaccccag atagtgattc aaagaaacga tattgatcaa gatgatctgt cagctctaga
    52321 ttcagcaagt ggcttgtatc aacgtaatgg gaagtgggtt tttcattaat gagtaatagc
    52381 tagaagggaa tttatgtata aagtttcaat tatttgcacc aattataaca aagctccttg
    52441 gatatctgat gcacttgaca gttttttaag ccaagtgaca gattttgagg ttgaaattat
    52501 tgttattgat gatgcttcta cagatgactc acgagagatt ttaaagagtt atcaaaaaaa
    52561 gtcttcagga aaaattaaat tactctttaa cgaaactaat attggaataa caaagacttg
    52621 gataaaagca tgcctttatg caaaaggcaa atatattgct agatgtgatg gtgatgatta
    52681 ctggacggat agttttaaac tccaaaaaca agttgatgtc ttagaagctt ccaaacggtc
    52741 acgatggtgt aatactgatt ttgactttgt aaatagtcaa ggcgacttat tatatgctaa
    52801 tgctttttca tctggtcata cacctttgac agatacttac gaaaaagttt tagccttaaa
    52861 agggatgacg atggcatcga catggttagt tgatgctgat ttaatgagac aagtaaacca
    52921 aaaaatcaat gtagatacac cagacgatac ttttgacatt caactagagt tatttcaact
    52981 gactcaactg acctatatta aagactcaac gacggtttat cgcatgacaa ccgattctga
    53041 ttcaagacct actgatacac caaaaatgat tcatcgtatt caaaaactac ttgatactca
    53101 gttaaattac ttaaaaaagt ataatcaggt agatacaaaa gaaatgtctg aactattatt
    53161 acaacaagat gctaagcaag aaatacgaat tcatgagttg agttgcttta ttcaagaatt
    53221 acaacaaact atcgtagata aaacaaagca gcaagaaaca cgtgaagtgg agttgcaaaa
    53281 tgtcatagaa gaacaaaaaa atcaactatc tgaattaaga caacaatacc atgccattat
    53341 taattcacgt caatggaaat acacgtctaa gctcattgct tttattagga gaaaaaaatg
    53401 aatcgtattt tattatatgt tcacttcaac aaatacaata aaataagtgc acatgtttac
    53461 tatcaattgg aacaaatgag atcactgttt tctaagattg tttttatctc aaatagtaaa
    53521 gtgagtcatg aagatttaaa acgtctcaaa aaccactgtc ttattgatga gtttttgcaa
    53581 cgcaaaaata aaggttttga tttttctgca tggcacgatg gcttgattac tatggggttt
    53641 gacaagttgg aagagtttga ctcattgacg attatgaacg atacttgttt tggtcctatt
    53701 tgggagatgg gtccttattt tgaaaatttt gaagaaaaag aggcagttga cttttgggga
    53761 attactaata atagaggtac aaaagctttt aaagaacatg tccaaagtta ttttatgacg
    53821 tttaaaaatc aagtcattca aaacaaagtt tttcaacaat tttggcaatc gataatagaa
    53881 tatgaaaacg ttcaagaagt gattcagcat tatgaaacgc aattaacatc cattctctta
    53941 aatgaaggct ttagttatca gacggtcttt gatactagaa aagctgagtc gtcattcatg
    54001 ccacatccgg atttttcata ttataatcca acagcaattc taaaacacca tgtgcctttt
    54061 ataaaagtaa aagctattga tgctaaccag catatcgctc cttacttact gaatctgata
    54121 cgagaaacaa ccaattatcc tatagatctt attgtttcac atatgtcgca aatctctttg
    54181 ccagatgcta agtacctttt atctcaaaaa tacctaaact gccaacggtt agcaaaacaa
    54241 acttgtcaaa aggtagctgt tcatttacat gttttttacg ttgatttgct agatgaattt
    54301 ttaacagctt tcgaagactg gaacttccat tatgatcttt ttattacaac agatagtgat
    54361 atcaaaagaa aagagatcaa agaaatactt caaagaaaag gtaaaactgc tgatatacgc
    54421 gttacgggaa atagaggaag agatatttat ccaatgttat tactaaaaga taaactttct
    54481 caatatgatt atattggtca tttccatacg aaaaaatcaa aagaagctga tttttgggca
    54541 ggagaatctt ggcgaaaaga attgattgat atgctcgtga aaccagcaga tagtattctt
    54601 agcgtttttg agacagatga tattggtatt ataatcgcag atattccaag tttttttaga
    54661 tttaataaga ttgtcaatgc ttggaatgag catttaatcg ctcaagaaat gatgtctttg
    54721 tggagaaaaa tggatgttaa aaaacaaatt gattttcaag ctatggatac atttgttatg
    54781 agttatggaa catttgtatg gtttaaatac gatgctctaa aatcactttt tgatttagaa
    54841 ttaactcaaa atgatattcc aagtgaacct ttaccacaaa actctatatt acatgcgatt
    54901 gagcggttat ttgtctatat agcgtggggg aattcttatg attttaggat tgttaaaaat
    54961 ccctatgagt taacaccttt tattgacaat aaactgttaa atttacgtga agatgaagga
    55021 gctcatacct acgttaactt taatcaaatg ggcggtatca aaggagcatt aaaatatatt
    55081 atcgttggtc ccgctaaagc aatgaagtat atattcttgc gtttaatgga gaaacttaaa
    55141 tgattaaaga cacattttta aaaaccaatt ggttaaatat tagtcaccat attatccttc
    55201 ttgttttcgg tttttatttc agtttttaca gtttggcgaa agaactagta agctccacgg
    55261 cacaaccggt aaactattat gctcatttac taaatgtttc ttttgtggga tatattatat
    55321 cactgattgg attatcttat tatttgagtc gccaagttag tcgacagttg tttttgaaaa
    55381 ctagttttat tgtgatatct tatctaattg tcagctattg ggtacaaata acacagcacc
    55441 tgaatgataa acggtttgat atctggtcat taactaaaaa tcaattttat caatttcaag
    55501 ctctaccttc tttactcatt attttagtga tggccacttt aataaaaata ttggtagcat
    55561 attttgcaat agaaaaagat agatttgggc tattaggcta tcaaggtaat actttttctg
    55621 tagctctgat tttagcagtt gtgccaatta atgacataca tctgttaaaa ctaataagtt
    55681 ctcgattttc tgaattagta agagcaggta atagccaaat tgcactgtta aaaataagtg
    55741 gactgttgat agttttactt gtcatatttg caacaatcat atacgtggtt ttaaatgctc
    55801 taaaacacct taagtcaaat aaaccttcat tttcagtagc agctactact agtttgtttt
    55861 tagcattagt ttttaactat acgtttcagt atggcgtaaa aggtgatgaa gcattgctag
    55921 gatattatgt tttccctgga gctactcttt ttcagatagt agctattaca ctagttgctc
    55981 ttttagcata cgtgataacg aatagatatt ggccaactac cttctttttg cttattctgg
    56041 gaacaattat ttctgttgtt aatgatttaa aagaatcaat gagaagcgag ccgttattag
    56101 taactgattt tgtttggtta caagaattag gtttagtgac aagctttgtt aaaaaatcgg
    56161 tgattgtaga aatggttgta ggacttgcta tttgtattgt ggtagcttgg tatctacatg
    56221 gccgagtttt agcagggaaa ttatttatga gccctgtcaa acgggcaagt gctgtattag
    56281 gtttatttat tgtatcttgt agtatgttaa taccattttc ttatgaaaaa gaaggtaaaa
    56341 tattatctgg tcttccgatt atttcggctt taaataatga taatgatata aactggttag
    56401 gtttttcaac aaatgctagg tacaaatctt tagcatatgt ttggacaaga caggtgacca
    56461 agaaaataat ggaaaaaccg acaaattata gccaagaaac aatagcgagt atcgctcaga
    56521 agtaccaaaa attagcagaa gatattaata aagacagaaa aaataatatt gctgaccaaa
    56581 cggttattta tcttttaagt gaaagtttgt cagatcctga tagagtatca aatgttactg
    56641 ttagccacga tgttttacct aatatcaagg caatcaaaaa tagcacaact gcgggactca
    56701 tgcagtcaga ctcctacggg ggtggaactg ctaacatgga gtttcaaacg ttaacaagct
    56761 taccttttta taatttttct tcttcagtat ctgttcttta ttcagaagtc tttcctaaaa
    56821 tggccaaacc tcatacgatt agtgagtttt accaaggaaa aaatcgtatt gcgatgcatc
    56881 ctgctagtgc taacaatttt aatagaaaaa cagtttatag taatttaggt ttttccaaat
    56941 tcttagctct atcgggttct aaggataagt ttaagaacat tgaaaatgtc ggtttattga
    57001 ctagcg
//
LOCUS       DATWEK010000009        53859 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.009, whole genome shotgun sequence.
ACCESSION   DATWEK010000009 DATWEK010000000
VERSION     DATWEK010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53859
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.009"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            584..673
                     /locus_tag="VCR92_000651"
     CDS             584..673
                     /locus_tag="VCR92_000651"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEP4267738.1"
                     /translation="MIIDYCNNKRIKIKRKGLSPLQYKTKSFT"
     gene            complement(711..1634)
                     /locus_tag="VCR92_000652"
     CDS             complement(711..1634)
                     /locus_tag="VCR92_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4267739.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFIKKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSSGQILYDGKVINGRKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEEERKEKIKNMMAEVGLLSEHLTRYPHEFSGGQRQRIG
                     IARALVMNPEFVIADEPISALDVSVRAQVLNLLKRMQAEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFNNPIHPYTQSLLSAVPIPDPILERQKELVVYHPDQHD
                     YTLDKPSMVEIKPNHFVWANQAEIEKYQKEL"
     gene            complement(1627..2697)
                     /locus_tag="VCR92_000653"
     CDS             complement(1627..2697)
                     /locus_tag="VCR92_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4267740.1"
                     /translation="MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFV
                     GESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQELTDLKTNKEWAKIRGSKIATIFQ
                     DPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
                     SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIVEFGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAI
                     PGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAKTWLLHPEAPKVQKP
                     EVIQDLHQKILRKMSQQEEGNV"
     gene            complement(2706..3632)
                     /locus_tag="VCR92_000654"
     CDS             complement(2706..3632)
                     /locus_tag="VCR92_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009569326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4267741.1"
                     /translation="MESIDKSKFRFVERDSEASEVIDTPAYSYWKSVFRQFFSKKSTV
                     FMLVILVTVLMMSFIYPMFANYDFNDVSNINDFSKRYIWPNAEYWFGTDKNGQSLFDG
                     VWYGARNSILISVIATLINITIGVVLGAIWGVSKAFDKVMIEIYNIISNIPSMLIIIV
                     LTYSLGAGFWNLILAFCITGWIGVAYSIRVQILRYRDLEYNLASQTLGTPMYKIAVKN
                     LLPQLVSVIMTMLSQMLPVYVSSEAFLSFFGIGLPTTTPSLGRLIANYSSNLTTNAYL
                     FWIPLVTLILVSLPLYIVGQNLADASDPRSHR"
     gene            complement(3632..5134)
                     /locus_tag="VCR92_000655"
     CDS             complement(3632..5134)
                     /locus_tag="VCR92_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4267742.1"
                     /translation="MKKYILNRIMRSLVSVVLVTALTYTIVYTLVPTSLIFKQDPNYN
                     KMTTTPDKKVAYENLTFQRMGYVNYFSSKELKDNASKVDSSVTTEATSANKAIYEKYI
                     DSLGNGWQLKRFPTSKQFYAIRNIPIYERVWNFFSNLVVIDHPWKIQDKDNPKLARYI
                     RLEKDKSVGWSLVGSGTKHKYLLYTNGKFPYLHQNFVTLNLGTSYPTYSNIPVLQVIS
                     QGQGRTALQDVTFPSGVTKKSSVDIYSRSYKNPKSLDDITKVNYGKGDSYTKTINNYV
                     DPSMIHNSFVIGFFGVMFSYIVGLPLGLFMARFKNTYFDRFSTATMTFMLALPSIAVI
                     YVVRFLGGMAGLPDSFPMLGASDPKSYILPALILGILNIPTTVIWFRRYLVDLQASDW
                     VRFARSKGLSESEIYRGHLFKNAMVPIVSGVPASIILAIGGATLTETVFAFPGMGKML
                     IDSIKSANNSMIVGLTFIFTVLSIVSLLLGDIVMTLVDPRIKLSTKKGGK"
     gene            complement(5199..7169)
                     /locus_tag="VCR92_000656"
     CDS             complement(5199..7169)
                     /locus_tag="VCR92_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEP4267743.1"
                     /translation="MKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVN
                     DPKSLDYILTNGGGTTDVITQMVDGLLENDEYGNLVPSLAKDWKVSKDGLTYTYTLRD
                     GVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEV
                     GVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGA
                     YFLSAFTSKSSMEFHKNENYWDAKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARL
                     YPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKNTKKDPAQQDAGKKALNN
                     KDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTVGESDFGSEVEKEMAKL
                     GDEWKDVNLADAQDGFYNPEKAKVEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQE
                     AQSFKQSVEASLGKENVIVNVLETETSTHEAQGFYAETPEQQDYDIISSWWGPDYQDP
                     RTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAITDDNDARYKA
                     YAKAQAYLTDSAVDIPVVALGGTPRVTKAVPFSGGFSWAGSKGPLAYKGMKLQDKPVT
                     AKQYENAKEKWMKAKAKSNAKYAEKLADHVEK"
     gene            7500..8732
                     /locus_tag="VCR92_000657"
     CDS             7500..8732
                     /locus_tag="VCR92_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEP4267744.1"
                     /translation="MIKRLISLVVIALFFAASTVSGEEYSVTAKHAIAVDLESGKVLY
                     EKDTKEVVPVASVSKLLTTYLVYKEVSKGKLNWDSPVTISNYPYELTTNYTISNVPLD
                     KRKYTVKELLSALVVNNANSPAIALAEKIGGTEPKFVDKMKKQLRQWGISDAKVVNST
                     GLTNHFLGANTYPNTEPDDENCFCATDLAIIARHLLLEFPEVLKLSSKSSTIFDGQTI
                     YSYNYMLKGMPCYREGVDGLFVGYSKKAGASFVATSVENQMRVITVVLNADQSHEDDL
                     AIFKTTNQLLQYLLINFQKVQLIENNKPVKTLSVLDSPEKTVKLVAQNSLFFIKPIHT
                     KTKNTVHITKKSSTMIAPLSKGQVLGRATLQDKHLIGQGYLDTPPSINLILQKNISKS
                     FFLKVWWNRFVRYVNTSL"
     gene            8900..10081
                     /locus_tag="VCR92_000658"
     CDS             8900..10081
                     /locus_tag="VCR92_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEP4267745.1"
                     /translation="MTKRIILTIFTFICFSVMPLVQAEDVMDITRQAGYTVSEVNRPK
                     SSIVVDANSSDILWQDNIDIPRDPASMSKMFTLYILFEELAKGKITMDTTITATPTDQ
                     AIANIYEISNNNIVAGVAYPIRDLITMTAVPSSNAATVMIANYLSNNDASAFIDRINA
                     TAKQLGMTNTHFSNASGAAAQAFQGYYNPTKYDLSASNITTARDLSKLLYAFLKKYPE
                     IISFTNKSVVHTMVGTPYEEEFHTYNHSLPDNQFGMKGVDGLKTGSSPSAAFNAMITA
                     KRGKTRLITIVMGVGDWSDQNGEFYRHPFVNALTEKGFKDSKTLSKKARQKLEKLVPQ
                     TKKETSPKQQHFKATKKQSYLERVEDFMNHNHTFLLICLAIFIITILLLSLVVFAMGR
                     Q"
     gene            complement(10233..11651)
                     /gene="sufB"
                     /locus_tag="VCR92_000659"
     CDS             complement(10233..11651)
                     /gene="sufB"
                     /locus_tag="VCR92_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEP4267746.1"
                     /translation="MSDINEKVEPKPIDLGDYQFGFHDDVEPIYSTGKGLSEAVVREL
                     SAAKNEPEWMLEFRLKSLETFNKMPMQTWGADLSDINFDDIIYYQKASDKPARSWDDV
                     PEKIKETFDRIGIPEAERAYLAGASAQYESEVVYHNMKGEFEKLGIIFTDTDSALKEY
                     PDLFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALTDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANAGQHQDT
                     GAKMIHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKQSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLISYEMEGSVG"
     gene            complement(11644..12123)
                     /locus_tag="VCR92_000660"
     CDS             complement(11644..12123)
                     /locus_tag="VCR92_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEP4267747.1"
                     /translation="MALSKLNHLYMAVVADHSKRPHHHGQLDGVEAVQLNNPTCGDVI
                     SLTVKFDEDKIEDIAFAGNGCTISTASSSMMTDAVIGKSKEEALALADIFSEMVQGQE
                     NPAQKELGEAELLAGVAKFPQRIKCSTLAWNALKEAIKRSANAQHLTDQNVKEGKNV"
     gene            complement(12110..13336)
                     /locus_tag="VCR92_000661"
     CDS             complement(12110..13336)
                     /locus_tag="VCR92_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEP4267748.1"
                     /translation="MLDAKDIKQDFQILNQQVNDEPLVYLDNAATTQKPALVLEALQS
                     YYQEDNANVHRGVHTLAERATHKYEASRQQVADFIHAKSSKEVLFTRGTTTSLNWVAR
                     FAEQVLTPEDEVLISIMEHHANIIPWQQACQKTGARLVYVYLKDGQLDMDDLANKLTT
                     KTRFVSLVHVSNVLGCINPIKEIAKLAHAKGAYLVVDGAQSVPHLAIDVQDLDCDFFA
                     FSAHKMLGPTGLGVLYGKEELLNQVEPLEFGGEMIDFVYEQEATWKELPWKFEAGTPH
                     IAGAIGLSAAISYLQRLGMADIHAHEAELIAYVLPKLEAIEGLTIYGPSQPSARSGLI
                     SFNLDDLHPHDLATALDYEGVAVRAGHHCAQPLLSYLGVPATVRASFYIYNTKADCDR
                     LVEAILKAKEFFNGTL"
     gene            complement(13367..14629)
                     /gene="sufD"
                     /locus_tag="VCR92_000662"
     CDS             complement(13367..14629)
                     /gene="sufD"
                     /locus_tag="VCR92_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEP4267749.1"
                     /translation="MTKEKLVAFSQAHAEPAWLQERRLAALEAIPELELPTIERVKFH
                     RWNLGDGTLTENESLASVPDFIAIGDNPKLVQVGTQTVLEQLPMALIDKGVVFSDFYT
                     ALEEIPEVIEAHFGQALAFDEDKLAAYHTAYFNSAAVLYVPDHLEITTPIEAIFLQDS
                     DSDVPFNKHVLVIAGKESKFTYLERFESIGNATQKTSANISVEVIAQAGSQIKFSAID
                     RLGPSVTTYISRRGRLEKDANIDWALAVMNEGNVIADFDSDLIGQGSQADLKVVAASS
                     GRQVQGIDTRVTNYGQRTVGHILQHGVILERGTLTFNGIGHILKGAKGADAQQESRVL
                     MLSDQARADANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVIAEIPIPSVHQEIIKVLDEKLLNR"
     gene            complement(14724..15494)
                     /gene="sufC"
                     /locus_tag="VCR92_000663"
     CDS             complement(14724..15494)
                     /gene="sufC"
                     /locus_tag="VCR92_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEP4267750.1"
                     /translation="MSILEINNLHVSIEGKEILKGVNLTLKTGEVAAIMGPNGTGKST
                     LSAAIMGNPNYEVTQGQILLDGVNILDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKADKDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGKDFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALATRLEKEGYAGIAQDLGIEYKEES"
     gene            complement(15616..16785)
                     /locus_tag="VCR92_000664"
     CDS             complement(15616..16785)
                     /locus_tag="VCR92_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEP4267751.1"
                     /translation="MFSFTIDYVLVLIGALLMSLFLTPLVRFLAFRVGAVDNPNARRV
                     NKVPMPTSGGLAIFMSFLVASLGLIPIASKGAMFFGQTYFSYILPVVIGATVITLTGF
                     LDDLYELSPKLKMFGILIGAVIVWAFTDFKFDSFKIPFGGPLLVFGPFLTLFLTVLWI
                     VSITNAINLIDGLDGLVSGVSIISLVTMAIVSYFFLPQKDFFLTLTILVLISAIAGFF
                     PYNYHPAMIYLGDTGALFIGFMIGVLSLQGLKNSTAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGQKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGITMLFSLISLLLNVSSRIGGV
                     LLMLGLLFGLEVFIEGLEIWGEKRTPLFNLLKFIGNSDYRQAMLLKWKEKKDLKH"
     gene            complement(16792..17553)
                     /gene="mecA"
                     /locus_tag="VCR92_000665"
     CDS             complement(16792..17553)
                     /gene="mecA"
                     /locus_tag="VCR92_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEP4267752.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSV
                     MDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEINKDINLEDLAEFGDMSQMTPED
                     FFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
                     YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLI
                     EHANPGSKTRAYLQEHGLQLMLDGAVEQLQKIELG"
     gene            complement(17699..18538)
                     /locus_tag="VCR92_000666"
     CDS             complement(17699..18538)
                     /locus_tag="VCR92_000666"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEP4267753.1"
                     /translation="MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKA
                     FIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIA
                     VPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKRNAQQEPAVTELARMSYKTAFFIGC
                     FQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGH
                     HLDFAQVLILLVASLTAFVVSLLAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFK
                     FVF"
     gene            complement(18604..20529)
                     /locus_tag="VCR92_000667"
     CDS             complement(18604..20529)
                     /locus_tag="VCR92_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEP4267754.1"
                     /translation="MKKILMTLVLCFSLLGIRIKAADVDYSITNYEGQLLLSKENTAR
                     FEQKVTYQFDTSYNGQYISLGRAGHLPAGFAIDQKPKVEVYQNGQQVPVSQEFSDLGD
                     GYRLKLYNAGQAGDKVDVKVIWQLHHLLTAYQDVAELNWTPISDWDKTLEKVSLTVTT
                     PTDIQDSNLWAHRGYYQKKPQVLKEGNSRYQINAKNVSGQLELHAYWDKKALLGEEPV
                     DVSTSKKNKIVALETKISRRRALLQLLFGKVIPLVEVGFLLWQLIQFIRLKKQFNRYH
                     LANHTDHSYEVPEDLSPLVLTQAIYGQSFAYLSPTASESQKLLIPKGVTFEALVQATL
                     LDLIDQKVLLLTKEEGKAYLEISQLDRVTDEEAAFLDMAFGNKVTLPVDQLFSQYHYD
                     ADTIKQLKKTYKGKKLEQEVRQSSEQVIKAMKKASAAITNNVLETIKKLNLPDTYRQM
                     TPAEKRKSNSVQGLGCLLLVLNSGLLIYLAIKESGLALIYLALMVLTMCLGFYISLKL
                     DQYKKLGIETPEGGVRLHQWQSFKNMIRDIDKFEDVAIEGLVVWNRVLVYATLFGYAK
                     KVERYLKVHRIALPEVYQAVRPGELSMVMYATTPTFLSSLSSATTSSNFSVSSGGGIS
                     GGGGFSGGGGGGGGGAF"
     gene            20727..22295
                     /locus_tag="VCR92_000668"
     CDS             20727..22295
                     /locus_tag="VCR92_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEP4267755.1"
                     /translation="MKKLILSCLVALALLFGGMSRAQANQYLRVGMEAAYAPFNWTQD
                     DASNGAVPIEGTSQYANGYDVQVAKKVAKAMNKELLVVKTSWTGLIPALTSGKIDMIA
                     AGMSPTKERRNEISFSNSYYTSQPVLVVTANGKYADATSLKDFSGAKVTAQQGVWHVN
                     LLTQLKGAKLQTPMGDFSQMRQALTSGVIDAYISERPEAMTAEAADSRLKMITLKKGF
                     AVAESDAAIAVGMKKNDDRMATVNQVLEGFSQTDRMALMDDMVTKQPVEKKAEDAKAS
                     FLGQMWAILKGNWKQFLRGTGMTLLISMVGTITGLFIGLLIGIFRTAPKAKHKVAALG
                     QKLFGWLLTIYIEIFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIFIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRKIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRHIERRFDADTYT
                     TGANQMQIAEVSNV"
     gene            22288..23028
                     /locus_tag="VCR92_000669"
     CDS             22288..23028
                     /locus_tag="VCR92_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEP4267756.1"
                     /translation="MSNSIIEIKNLKKSYGSNEVLKDISLSVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGQILFHGEDVLAEHYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRDRAQAEQIAKENLNAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVGEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDHIIFMDKGL
                     ITEEGSPQQIFENPTQDRTKEFLQRFLK"
     gene            23170..23286
                     /locus_tag="VCR92_000670"
     CDS             23170..23286
                     /locus_tag="VCR92_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEP4267757.1"
                     /translation="MAEKTDLSSAYRRLKSPNIKTRKRALKIIHEYKRYGKK"
     gene            complement(23512..24522)
                     /gene="gap"
                     /locus_tag="VCR92_000671"
     CDS             complement(23512..24522)
                     /gene="gap"
                     /locus_tag="VCR92_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEP4267758.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNIEGVEVTRINDLTDPNMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGNFIKVSAERDPENIDWATDGVEIVLEATGFFAK
                     KEAAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPM
                     AKALHDAFGIQKGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVVTLDKNVSVDEINAAMKAASNDSFGYTED
                     PIVSSDIVGVSYGSLFDATQTKVMEVDGSQLVKVVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            complement(24870..26948)
                     /gene="fusA"
                     /locus_tag="VCR92_000672"
     CDS             complement(24870..26948)
                     /gene="fusA"
                     /locus_tag="VCR92_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEP4267759.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            complement(27315..27785)
                     /gene="rpsG"
                     /locus_tag="VCR92_000673"
     CDS             complement(27315..27785)
                     /gene="rpsG"
                     /locus_tag="VCR92_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEP4267760.1"
                     /translation="MSRKNQAPKREVLPDPLYNSKIVTRLINRVMLDGKRGTAATIVY
                     DAFSAIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVNASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            complement(27806..28219)
                     /gene="rpsL"
                     /locus_tag="VCR92_000674"
     CDS             complement(27806..28219)
                     /gene="rpsL"
                     /locus_tag="VCR92_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEP4267761.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVQTKMAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            complement(28427..31048)
                     /locus_tag="VCR92_000675"
     CDS             complement(28427..31048)
                     /locus_tag="VCR92_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEP4267762.1"
                     /translation="MDLEQTKPNQVKQKIALTSTIALLSASVGVSHQVKADDRASGET
                     KASNTHDDSLPKPETIQEAKATIDAVEKTLSQQKAELTELATALTKTTAEINHLKEQQ
                     DNEQKALTSAQEIYTNTLASSEETLLAQGAEHQRELTATETELHNAQADQHSKETALS
                     EQKASISAETTRAQDLVEQVKTSEQNIAKLNAMISNPDAITKAAQTANDNTKALSSEL
                     EKAKADLENQKAKVKKQLTEELAAQKAALAEKEAELSRLKSSAPSTQDSIVGNNTMKV
                     PQGYPLEELKKLEASGYIGSASYNNYYKEHADQIIAKASPGNQLNQYQDIPADRNRFV
                     DPDNLTPEVQNELAQFAAHMINSVRRQLGLPPVTVTAGSQEFARLLSTSYKKTHGNTR
                     PSFVYGQPGVSGHYGVGPHDKTIIEDSAGASGLIRNDDNMYENIGAFNDVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAINFLRVDKRNPNAPVYLGFSTSNVGSLNEHFVMFP
                     ESNIANHQRFNKTPIKAVGSTKDYAQRVGTVSDTIAAIKGKVSSLENRLSAIHQEADI
                     MAAQAKVSQLQGKLASTLKQSDSLNLQVRQLNDTKGSLRTELLAAKAKQAQLEATRDQ
                     SLAKLASLKAALHQTEVLAEQAAARVTALVAKKAHLQYLRDFKLNPNRLQVIRERIDN
                     TKQDLAKTTSSLLNAQETLAALQAKQSSLEATIATTEHQLTLLKTLANEKGYRHLDED
                     IATVPDLQVAPPLTGVKPLSYSKIDTTPLVQEMVKETKQLLEASARLAAENTSLVAEA
                     LVGQTSEMVASNAIVSKITSSITQPSSKTSYGSGSSTTSNLISDVDESTQRALKAGVV
                     MLAAVGLTGFRFRKESK"
     gene            complement(31039..31878)
                     /gene="purR"
                     /locus_tag="VCR92_000676"
     CDS             complement(31039..31878)
                     /gene="purR"
                     /locus_tag="VCR92_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEP4267763.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEEANIGDIDTLTGASGGVIFTPSISETEARTIVEDLCQRLSESDRILPGGY
                     IYLSDLLSTPKILQNIGRIIANAFKGEKIDAVMTVATKGVPLANAVANILSVPFVIVR
                     RDLKITEGSTVSVNYASASSDRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMISL
                     LTEFDSTLVGVAVFAENAQSEREQMTFKSLLKVSEIDVKNNNVVVEVGNIFDKWKKER
                     EWT"
     gene            complement(32145..33083)
                     /locus_tag="VCR92_000677"
     CDS             complement(32145..33083)
                     /locus_tag="VCR92_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEP4267764.1"
                     /translation="MKINQMKKDQLFEGFYLIKSAEVRKTRAGKDFISLTFQDDTGEI
                     SGNLWDAQPYNVEEFTAGKVVFMKGRREVYNGTPQVNQITLRNVRPGEPNDPKDFKEK
                     APVSVTEVRDYLEQMLFKIENATWQRIVRALYRKYDKEFYTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPDLNKSLLFAGIMLHDLAKVIELTGPDNTEYTVRGNLIGHIS
                     LINEEITKVISELQIDDTKEEVIVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMTTALSRVSEGEMTNRIFAMDNRSFYKPNY"
     gene            complement(33073..34344)
                     /locus_tag="VCR92_000678"
     CDS             complement(33073..34344)
                     /locus_tag="VCR92_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEP4267765.1"
                     /translation="MDLILFLLVLVLLGLGAYLLFKVNGLQHQLAQTLEGNADNLSDQ
                     ITYQLDTANKQQLLELTQLMNRQQADLYQQLTDIRDVLHRSLSDSRDRSDKRLEEINQ
                     QVNQSLKNMQESNEKRLEEMRQIVEEKLEETLKNRLHASFDSVSKQLESVNKGLGEMR
                     SVAQDVGTLNKVLSNTKTRGILGELQLGQIIEDIMTSSQYEREFVTVSGSSERVEYAI
                     KLPGNGQGGYIYLPIDSKFPLEDYYRLEDAYEVGDKLAIEASRKALLAAIKRFAKDIH
                     KKYLNPPETTNFGVMFLPTEGLYSEVVRNAAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNIQKNADDISKILGNVKLEFDKFGGLLAKAQKQMNTANNTLDQLISTRTNAI
                     VRALNTVETYQDQTTKSLLNMPLLEEENNEN"
     gene            complement(34346..34978)
                     /locus_tag="VCR92_000679"
     CDS             complement(34346..34978)
                     /locus_tag="VCR92_000679"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEP4267766.1"
                     /translation="MSKVALFAGGDLSYISRDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSVSQKAFTDIKEKAELFITAHPEKNDTDTELALKEVFARFPEAEVTIFGAFGGRM
                     DHLLSNIFLPSDPGIAPFMAQIALRDQQNMITYRPAGQHLIHQEEGMTYVAFMAEGEA
                     DLTITGAKFELTQDNFFKKKIYSSNAFIHQPITVSLPSGYLIIIQSKDWS"
     gene            complement(34971..35633)
                     /locus_tag="VCR92_000680"
     CDS             complement(34971..35633)
                     /locus_tag="VCR92_000680"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEP4267767.1"
                     /translation="MSTLKIAPSILAADYANFASELARIEETDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVDPERYVEAFAQAGVDIMTIHTESTRHIHGAL
                     QKIKAAGMKAGVVINPGTPATALEPLLDLVDQVLIMTVNPGFGGQAFIPECLEKVATV
                     AKWRDEKGLSFDIEVDGGVDNKTIRACYEAGANVFVAGSYLFKASDLVSQVQTLRTAL
                     NV"
     gene            complement(35643..36515)
                     /gene="rsgA"
                     /locus_tag="VCR92_000681"
     CDS             complement(35643..36515)
                     /gene="rsgA"
                     /locus_tag="VCR92_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEP4267768.1"
                     /translation="MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVD
                     FSAEDNSEGYILAIHPRKNSLVRPPIVNIDQAVVIMSAKEPEFNSNLLDRFLILLEHK
                     AIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYDFVTSLEELLPLLADKITVFMGQTGV
                     GKSTLLNRIAPELALETGEISDSLGRGRHTTRAVSFYNTHGGKIADTPGFSSLDYDIA
                     NAEDLNEAFPELRRLSHECKFRSCTHTHEPKCAVKAALETGELWPVRYEHYLQFLSEI
                     ENRRETYKKVIKRK"
     gene            complement(36939..37811)
                     /gene="rsmA"
                     /locus_tag="VCR92_000682"
     CDS             complement(36939..37811)
                     /gene="rsmA"
                     /locus_tag="VCR92_000682"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEP4267769.1"
                     /translation="MRIADYSVTKAVLDRHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DQNVNVIEIGPGIGALTEFLAENAAEVMAFEIDDRLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQIKQFKNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRDQPLIEVKD
                     EDFFFRVSRLSFVHRRKTLWNNLTSHFGKSEDIKTKLEKGLALADIKPSIRGEALSIQ
                     DFGKLADALKEVGL"
     gene            complement(37925..38515)
                     /gene="rnmV"
                     /locus_tag="VCR92_000683"
     CDS             complement(37925..38515)
                     /gene="rnmV"
                     /locus_tag="VCR92_000683"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEP4267770.1"
                     /translation="MQRGYLSLTEKINIQEVLVVEGKDDTANLRRFYEVDTYETRGSA
                     ITEEDLERINRLNDLRGVIVLTDPDYNGERIRKLIMAAVPTARHAFLNRNEAVPSSKS
                     KGRSLGVEHANFEDLQKALAHVTQQYDDESYFDIRQTDLIRLGLLMASDSRKRREYLG
                     EKLRIGYANGKQLLKRLELFGITLAEVEEVMETYEE"
     gene            complement(38487..39278)
                     /locus_tag="VCR92_000684"
     CDS             complement(38487..39278)
                     /locus_tag="VCR92_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEP4267771.1"
                     /translation="MTNKVEKLTIFDTHTHLNVAEFQGHETEELTLAQEMGVAYHNVV
                     GFDQATISGALALADQYPNVYATIGWHPTEAGSYSEAVEESIVSQLSHPKVIALGEIG
                     LDYYWMEDPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEVIKAAGVGPRGGIM
                     HSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILVETDAPYLTPV
                     PKRGKQNHTAYTRYVVDKIAELRGMTVEEVAKETTANAKRVLKLD"
     gene            39563..40393
                     /locus_tag="VCR92_000685"
     CDS             39563..40393
                     /locus_tag="VCR92_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEP4267772.1"
                     /translation="MPKNHRLITKIEASLEHMTSLEKGIAHFFITTDLTPQELTASEI
                     VKRLHISQAALTRFAKKCGFTGYRAFAFDYLHSLQESQETFQSIHLELTKRVLMDYDA
                     LINKTYELVNEEKLLNLAKLIDASERVYFFGKGSSGLVAREMKLRFMRLGLICDAYSD
                     TDGFTWANSLVNENCLVFGFSLSGKTNSVITALHQASQRGAKTVLLTTDNQTEFDDSL
                     DIIPVSSTHQLHYGNRVSPQFPLLIMMDIIYAYVLAIDKPHKEKIFKNTIIDKENNGL
                     "
     gene            complement(40504..41442)
                     /locus_tag="VCR92_000686"
     CDS             complement(40504..41442)
                     /locus_tag="VCR92_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEP4267773.1"
                     /translation="MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILE
                     KVKGLVKTYQDQMDLAGVAISSAGMVNPDKGEIFYAGPQIPNYAGTQFKKEIEETFGL
                     PCEVENDVNCAGLAEAISGSAKDYPVALCLTIGTGIGGCLLFNSQVFHGSSHSACEVG
                     YLHLSDGQFQDLASTTALVQEVALAYGDDISQWDGRRIFEQAKAGDAICIAAISKQVD
                     YLGQGIANICYVVNPNVVVLGGGIMVQKDYLADKLKTALDSYLVSSLAKKTQLKFASH
                     GNNAGILGAYYHFKQKNERSCSFITLEKIENNLASS"
     gene            complement(41464..42378)
                     /locus_tag="VCR92_000687"
     CDS             complement(41464..42378)
                     /locus_tag="VCR92_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEP4267774.1"
                     /translation="MTDLTKYQGIIPAFYACYDDQGAISPERVRALTQYYIDKGVQGL
                     YINGSSGECIYQSVFDRQLVLENVMAVAKGKLTIINHVACNNTKDSIELAAHSERLGV
                     DAIAAIPPIYFRLPEYAVADYWNAISSAAPHTDFIIYNIPQLAGVALTPSLYKTMLAN
                     KRVIGVKNSSMPVQDIQTFCAIGGDDHIVFNGPDEQFLGGRLMGAAAGIGGTYGAMPE
                     LFLRLNQLIVDKDLEKAKTLQYTINETIGVLVSAHGNMYGVIKEVLRINEGLDIGSVR
                     SPLAELVEEDRVICQRAAALINQAKETF"
     gene            complement(42390..43052)
                     /locus_tag="VCR92_000688"
     CDS             complement(42390..43052)
                     /locus_tag="VCR92_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEP4267775.1"
                     /translation="MTSKKQGLLHSLFKLDSKWMRASAALFDLLVFNLLFVLSCLPLL
                     TIGVAKMALYASLLDWREGQVSQLVTTYSSHFKHYFKSGMRLGLIELLIMSICVLDLF
                     LIRNQSGLVFQGFKVLCIAVLFLVVILFLYAYPQAVRKELPLLILFKRSLLLAGILFP
                     WTFAFLVVIGLLVFTLPLTLLTLFCGLSLLATMGISSLTYLYLIIMESLLRRFPLNND
                     IE"
     gene            complement(43209..44039)
                     /locus_tag="VCR92_000689"
     CDS             complement(43209..44039)
                     /locus_tag="VCR92_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEP4267776.1"
                     /translation="MTKKKLTASDVLTTVILCILTILFIFPFYWIMTGAFKAQADTIM
                     IPPQWWPKAPTIENFKALVVQNPALKWLWNSVFISVATMFLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIVKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRENLTISLGVATMQAEMATNYGLIMAGAAMAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            complement(44052..44939)
                     /locus_tag="VCR92_000690"
     CDS             complement(44052..44939)
                     /locus_tag="VCR92_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP4267777.1"
                     /translation="MNVNKLKMRETLISYAFLAPVLVFFVIFVLIPMIMGFVTSFFNY
                     SMTDFTFVGFANYARMFQDPIFMKSLINTLIIVIGSVPVVVFFSLFVAAKTYDKNVVA
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYAHVIEQNISWLGDKHWAL
                     LAIIAILLTTSVGQPIILYIAAMGNIDNSLMEAARVDGATEFQVFWNIKWPSLLPTTL
                     YIAVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAV
                     MIAIISFAQFKILGNDVEY"
     gene            complement(45042..46361)
                     /locus_tag="VCR92_000691"
     CDS             complement(45042..46361)
                     /locus_tag="VCR92_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEP4267778.1"
                     /translation="MNMKKLASLVMLGASVLGLAACGGKSQKEAGASKSDTAKTEITW
                     WAFPVFTQEKAEDGVGTYEKKLIAAFEKANPEIKVKLETIDFTSGPEKITTAIEAGTA
                     PDVLFDAPGRIIQYGKNGKLADLNDLFTEEFTKDVNNDKLIQASKAGDTAYMYPISSA
                     PFYMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPR
                     AFFANLYSSHITDDKVTKYTTDDANSIKAMTKISNWIKDGLMMNGSQYDGSADIQNFA
                     NGQTSFTILWAPAQPGIQAKLLEASKVDYLEIPFPSDDGKPELEYLVNGFAVFNNKDE
                     QKVAASKTFIQFIADDKEWGPKNVVRTGAFPVRTSYGDLYKDKRMEKIAEWTKFYSPY
                     YNTIDGFAEMRTLWFPMVQAVSNGDEKPEDALKAFTEKANKTIKKTQ"
     gene            complement(46410..47114)
                     /locus_tag="VCR92_000692"
     CDS             complement(46410..47114)
                     /locus_tag="VCR92_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEP4267779.1"
                     /translation="MPDKPTKEKLMEQLKGGIIVSCQALPGEPLYSETGGIMPLLAKA
                     AQEAGAVGIRANSVRDIKEIQAITDLPIIGIIKKDYPPQEPFITATMAEVDQLAALNI
                     AVIAMDCTKRDRHDGLDIASFIRQVKEKYPNQLLMADISTFDEGLVAHQAGIDFVGTT
                     LSGYTPYSRQEAGPDVALIEALCKAGIAVIAEGKIHSPEEAKKINDLGVAGIVVGGAI
                     TRPKEIAERFIEALKS"
     gene            complement(47388..47522)
                     /gene="rpmH"
                     /locus_tag="VCR92_000693"
     CDS             complement(47388..47522)
                     /gene="rpmH"
                     /locus_tag="VCR92_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEP4267780.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLAARRRKGRKVLSA
                     "
     gene            complement(47837..48751)
                     /locus_tag="VCR92_000694"
     CDS             complement(47837..48751)
                     /locus_tag="VCR92_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEP4267781.1"
                     /translation="MVLFTGKTVEEAIETGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGISDKTVYKADKKATRGVPEDINQKNAPAVNSADVEPEEIKATQKLEAED
                     TKVVPLMSEDSPAQTLSNLAETVTETKAQQPSIPVEESEVPQDPGNDGFSKDIEKAAQ
                     EVSDYVTKIIYEMDIEATVETSNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNF
                     LHDRYSKNFSVSLNVHDYVEHRTETLIDFTQKVAKRVLESGQDYTMDPMSNSERKIVH
                     KTVSSIEGVDSYSEGNDPNRYVVVSLQR"
     gene            complement(48763..49590)
                     /locus_tag="VCR92_000695"
     CDS             complement(48763..49590)
                     /locus_tag="VCR92_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEP4267782.1"
                     /translation="MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVY
                     LFARAIQWLSFDGSIGVGIILFTLTIRLMLMPLFNMQIKSSQKMQDIQPELRELQKKY
                     AGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTF
                     LWVELAQHDHLYLLPVLAAVFTFLSTWLTNLAAKEKNVMMTVMIYVMPLMIFFMGFNL
                     ASGVVLYWTVSNAFQVVQLLLLNNPFKIIAERQRLANEEKERRLRERRARKKAMKRK"
     gene            complement(49556..49915)
                     /gene="rnpA"
                     /locus_tag="VCR92_000696"
     CDS             complement(49556..49915)
                     /gene="rnpA"
                     /locus_tag="VCR92_000696"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEP4267783.1"
                     /translation="MKKTYRVKREKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGI
                     SVGKKIGNAVTRNAVKRKIRHVIMALGHQLKSEDFVVIARKGVESLEYQELQQNLHHV
                     LKLAQLLEKGFESEEKH"
     gene            complement(50455..51195)
                     /locus_tag="VCR92_000697"
     CDS             complement(50455..51195)
                     /locus_tag="VCR92_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP4267784.1"
                     /translation="MMNIFILEDDFIQQTRIESIVVGILKETRIPCNQLEVFSTPQKL
                     FESIQERGDHQLYFLDIEIGEYTRCGLELAAAIRQKDPNAVIVFVTTHSEFAPISFKY
                     KVSALDFIDKAGGQKQFKEQIEECIRYTYDMMSSRESKDMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDKVVRIDKSKQ
                     LLYFENGDSCMVSRLKMKCLFERWEALR"
     gene            complement(51199..52482)
                     /locus_tag="VCR92_000698"
     CDS             complement(51199..52482)
                     /locus_tag="VCR92_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP4267785.1"
                     /translation="MMVIYSMALFYATIFINSWVIFAKVSAIKLSWKRVSVIGISFVI
                     ANMIFDKVILIDQLFFIIVSLLSAPKKKLFEHMFNGFFTILIVELLFRVIGSFFLPAV
                     LGFSIGQINNNLKLLELCYLFVLPIFYLFSYIFSIDLSLIRFISEDKMKKWVFWMNTA
                     MFSYYFFAHFLVTVQSGFLALYFQYRSILVFIYLAIFIWVIVKLDRFAKDQLSQKLTQ
                     AQNERIAYLENYNQSIEQLYREIRTVKHDSENILISLKDSIDSGDIDLITRVYDTVIQ
                     QSATSMMRTNYEISSLDNIKEAVIRSIMNSKLLEAQYLGIELYIEIPDVIDHLPIKLI
                     DLIVLFTGLVDNAIETAKGSRRPFLSIAYFKQDNKQLFIIENSTKTNRVDIAKRFDAQ
                     QQNSAHFLTVLDSYPQITLSTKSDHYRLRQLLEMR"
     gene            complement(52479..53825)
                     /locus_tag="VCR92_000699"
     CDS             complement(52479..53825)
                     /locus_tag="VCR92_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP4267786.1"
                     /translation="MANSEYMFLLLSIIVYYMTKIYIFSFLSDITLPVWKQLTILALA
                     LFFNQFPYLSPLLIDPLLFLVVLRQETKQLFSLKALFLAVAPSVLVDLLSRFMGTIVI
                     PYLFLSSGIYLGHIIFDLLAYLLIFPSFAIINYMIGKDYKMICQSGYSKRSHNFYQTL
                     LIFVLVYYVDIFVILGFTDPFLHFHHSLFVPTPYKLLFLMFILLLVYLLSYFNHSSKE
                     YLKNELRREQQAYMTNLETYGKHLEKLYRDVRAFQSDYLSRIERLGQAIKSESITQIQ
                     DIYAQTVHEANDYWDDKHYNISKLRKINISSIKSLLSAKIISAEKSGIDLNVEVPDNI
                     KETYIPELDLLLLMSIFCDNAIEAALEAQQPHMSIAYFLLDDYQMFVVTNTTKKKVDI
                     NKIFEEGYSSKGSERGIGLSNAQRILKKYPYLSLRTKSFDKEFSQTLTMPKEEVDR"
BASE COUNT        16367 a        11284 c         9793 g        16415 t
ORIGIN      
        1 ctttttttgt acttttttat ttgcccgcgt tgtaaaatga agtgcaacaa aaaagagaaa
       61 aagccttgaa ctacacccca aacgttagac aaaaaaatct aacgttcggg gtatttttta
      121 tgaaattaag tgatgaaagt acgaaataga catcgttaag aaagaaaaaa atacctacta
      181 tccaccagag ataaagcaag aaataatgga taacgttttg atagaaggcc cgccacaata
      241 ccaagtatca cttgtttatg gcttgttaca tgcaggaact ctcccaagtt gaatagtaca
      301 atataagaaa aacagttata ctgttgagaa aacaagagca agaccatcac aaacaggacg
      361 taaaccaaaa gaaacctgaa gaaatgacta aattagagcg gcttcaagaa gaaaatgaat
      421 atctcagaac tgaggttgct tacttaaaaa aaccgaggaa ctccgtttga aagaagcatc
      481 tctgtaaaga agaagacaaa aaaaccatta taaaaaatgg acaaagacga gttctgatta
      541 gattttcttt taagaacggc tgtattgact cgttctacct accattatca tcgattattg
      601 caacaataaa cgtatcaaaa taaaacgaaa aggacttagt cctctacaat acaaaactaa
      661 atcctttact taaaatagag tagccaactt ttggggtcag tgcatctctt ttacaattct
      721 ttttgatatt tttcaatttc tgcttggttt gcccaaacaa agtgatttgg tttgatttca
      781 accattgatg gcttatctaa tgtataatca tgttggtctg gatgatagac aacaagttct
      841 ttttgacgct ctaaaattgg atctgggata ggcacggctg ataacaaaga ttgggtgtag
      901 ggatgaattg ggttattaaa cagttcttct gtttctgcaa cttctacaat aaccccttta
      961 tggataaccg caatacgatc tgaaataaag cgaacgactg aaagatcatg ggcaatgaag
     1021 agataagtca aacctttttc ggcttgcatc cgtttgagaa ggtttaaaac ctgtgcgcga
     1081 acggaaacgt ccaaagctga aatcggttca tcagcaataa cgaattcagg gttcattact
     1141 agggctctag cgataccgat ccgctgacgt tgacctcctg aaaattcatg agggtagcgc
     1201 gtcaaatgct ctgatagcaa accaacttcg gccatcatgt tcttaatttt ttctttacgt
     1261 tcttcctctg ttttaaacag attaaagtta taaagacctt ctgaaatgat gtagtcaacg
     1321 gttgcccgtt cattcaaact agcagcggga tcttggaaaa tcatttgaat tttacgaatg
     1381 agctcattgg cttctgattt tgattttctg ccattaatta ctttcccatc gtataaaatt
     1441 tgacctgagc tagtatcgtt caaaccaata atagcacgac caattgttgt tttaccactc
     1501 ccagattctc caactaaaga aaaggtttct ccttttttaa taaagaaatt agcattttta
     1561 actgcaacaa attttttctt tccttctccg aaggaaattt ctaggtcttt tacttcgact
     1621 aatttctcag acatttcctt cctcctgttg tgacattttc cttaagattt tttgatgcaa
     1681 atcttgaatg acttctggtt tttgaacttt tggagcctct gggtgtaaaa gccatgtttt
     1741 ggcccaatga gtctcagata cgttaatcgc cggaggtgct ttttcaaagt ctaaaaccat
     1801 agcatattct gagcgaagtg caaaggcatc tccgataatt ggtgaataaa gtgatggagg
     1861 cgttcctgga atagcgtaaa gttcaccaga ttcatctgcc aactgcggta agctagacag
     1921 caaactccat gtataggggt gccttggatc atagaaaatc tcttcgactg ttccaaattc
     1981 aacaatttct cctgcataca tgacagccac tttatctgca atgcttgcca caacacctaa
     2041 atcgtgcgta ataaagataa tggtgaaatg atattctcgt tgaagcgact tcaataactc
     2101 aacgatttga gcttgaatag tcacatcaag ggctgttgtt ggctcatcac agataagaat
     2161 atctgggcga caagctaaag caatagcgat aacaatacgt tgacgcattc ctcctgaata
     2221 ctcaaatggg taatcttcaa agcgtttttt ggcatttggg atacccactt tattcatgta
     2281 atcaagggcc atttctttag ctttggcatg acttactttt tggtgcttaa taatcacttc
     2341 tgtgatttgg ctaccaatag ttttaatggg actaagactg gtcattgggt cttggaaaat
     2401 cgttgcgatt tttgagccgc gaatctttgc ccactcttta tttgttttta aatctgtcaa
     2461 ttcttgccca cgatagacaa ttgaaccatt agcaatgcgt ccattagact ccaacatccc
     2521 tgtaaaggtc tttgttaaaa cagatttacc tgagcctgat tcccctacaa aagcaaggac
     2581 ttctccttca acaagttcca gtgagacgtt acggatagct gttaaaacac gatcacgcac
     2641 atcaaattct accaccacat ctttggcagt taagattaca ttattttctt ttgtcatttt
     2701 aactcctatc tatgtgaacg tgggtcactg gcatcagcca agttttgtcc gacaatgtat
     2761 agtggtaacg atactaaaat caatgttact aagggaatcc aaaagaggta ggcatttgtt
     2821 gttaagttgc ttgaataatt agcaatcaaa cgtcctaaac ttggagtggt ggttggtaaa
     2881 ccaatcccaa agaaggataa gaaggcctca gaagatacat aaactggtag catttgtgac
     2941 aacatagtca tgataactga aaccaattga ggcaggaggt tcttaacagc aatcttgtac
     3001 attggtgttc ccaaagtttg actagcaagg ttgtattcta aatcacggta acgcaagatt
     3061 tgaacacgga tggagtaggc gacaccaatc catccagtga tacagaaagc tagaatcaaa
     3121 ttccaaaatc ctgcacctaa tgaataggtc aaaacaatga taataagcat agaagggata
     3181 tttgagataa tgttataaat ttcaatcata actttatcaa atgctttaga aactccccat
     3241 atggctccta acactacccc aatggtgata ttaattagtg tcgctataac tgagattaaa
     3301 atagaattac gtgccccata ccaaacacca tcaaacagag attgcccatt tttgtcggtt
     3361 ccaaaccagt actctgcatt tggccaaata taacgctttg aaaagtcatt gatattacta
     3421 acgtcattaa agtcgtagtt ggcaaacatt ggataaataa agctcatcat caagactgtc
     3481 actaaaatca cgagcataaa gactgtagat tttttagaaa aaaactgacg aaacactgat
     3541 ttccagtaag aataagcagg ggtatcaatc acttcggagg cttcactatc gcgctcaaca
     3601 aatcgaaatt tagatttatc aatcgattcc attacttacc tccttttttt gttgacaatt
     3661 taatacgtgg atcgacaagg gtcatgacaa tatctcctag taaaagtgaa acaattgaca
     3721 agacagtgaa gataaaggtt aatccaacaa tcatagaatt gttagcagat ttaatagaat
     3781 caattaacat tttacccata cccgggaagg caaagacagt ctctgttaag gttgcaccac
     3841 caatagcaag gataatactt gcaggaaccc ctgacacaat tgggaccatg gcatttttga
     3901 agagatgccc tctgtaaatt tcagattctg ataatccttt tgaacgcgca aaacgtaccc
     3961 aatcactggc ctgaaggtca acaagatagc gacggaacca gataaccgta gttggaatat
     4021 ttaaaattcc taaaataagg gctggtaaaa tataagattt aggatcagat gcccctagca
     4081 ttgggaaact atctggtaaa ccagccatgc cacctaggaa gcgaacaaca tagataacag
     4141 caatacttgg taaagcaagc atgaaggtca tggtcgctgt tgagaaacgg tcaaaatagg
     4201 tatttttaaa ccgagccata aataaaccaa gaggcaagcc aacgatatag gaaaacataa
     4261 caccaaaaaa accaattaca aaagaattgt gaatcattga tgggtcgaca taattattga
     4321 tggttttagt gtaggaatct cccttaccat agtttacctt ggtgatatca tccaatgatt
     4381 ttggattttt gtagctacgg ctatagatat ccactgacga tttcttagtg acacctgatg
     4441 ggaaggtcac atcttgaaga gctgttcgtc cttgcccttg tgaaataacc tgaagaacag
     4501 gaatattgct gtatgttggg taagatgttc ctaagtttag ggtaacaaag ttttggtgaa
     4561 gataaggaaa ttttccgtta gtgtagagga gatatttatg ttttgtcccc gaaccaacaa
     4621 gtgaccagcc aactgattta tctttttcta gacgaatata cctagctaat tttggattgt
     4681 ctttatcctg aatcttccaa gggtgatcaa taacaactag atttgagaaa aagttccaaa
     4741 cacgttcgta aataggaata ttgcgaattg cataaaactg tttgctagtg gggaagcgtt
     4801 ttagctgcca gccattgcca agagaatcaa tatacttctc atagatagct ttgttagcac
     4861 tagttgcttc tgtcgttaca ctactatcta ctttagaagc attatctttt aattctttgc
     4921 ttgaaaaata attgacataa cccatacgtt gaaaagttag attttcatac gctacttttt
     4981 tatctggtgt tgttgtcatt ttattataat tagggtcttg tttaaagata aggctggtag
     5041 gtactagagt atatacgatg gtgtatgtta aagccgttac caaaactacc gacactaacg
     5101 atcgcatgat acggtttaaa atgtattttt tcatagttat cctcaatagt tcaaaagaac
     5161 ttcctcacat aaacgagaaa gttcttttga acatcgtttt atttttcaac gtgatcagct
     5221 aacttctcag catattttgc atttgactta gcctttgctt tcatccattt ttcttttgca
     5281 ttttcgtatt gttttgctgt gacaggtttg tcttgaagtt tcattccttt atatgctaga
     5341 ggacctttag accctgccca agagaagccc ccgctaaatg gaacggcttt agtaactcgt
     5401 ggagtgccac ccaatgccac aactggaata tctacggcac tatctgtaag gtaggcttgt
     5461 gcttttgcgt aagctttata gcgcgcatcg ttgtcgtctg taattgctgc tgcttcatca
     5521 aggagagttt ggtaagtatc aaggcctgca gctgccacaa catccttatt ttgacctgct
     5581 ttgattccaa gtttttggat aacagatcca ccacctactg gactcatgat gtcaaggtag
     5641 gtccgtggat cttggtagtc tggtccccac catgatgaaa tgatatcgta gtcttgttgt
     5701 tctggggtct cagcatagaa gccttgggct tcgtgagttg atgtttctgt ttcaagaaca
     5761 ttgacaatga cattttcttt accaagagat gcttcaacag attgtttgaa agactgggct
     5821 tcctgaacag ttgctgcgtt tgcctggtca acagggtaat ctaattgaac tgggaaggtt
     5881 acaccttcag ctgtcaaagc ttctttggct tttgcaaatt caacttttgc tttttcagga
     5941 ttatagaaac catcttgagc atcagctaag ttaacgtctt tccattcatc accaagtttt
     6001 gccatttcct tttcaacttc tgaaccaaaa tcactttctc caacggttac aaaagttggt
     6061 ggcacaagca tgttacgtaa ggcttttgtt ttggcatctt gacctgcagt ttgtgcttgg
     6121 aatgacgctc ggtcaaaagc aaactgaata gcttgacgaa aatccttgtt gttaagagct
     6181 ttcttaccgg catcttgttg tgcagggtct ttcttagtgt ttttgaaaga agtacggttc
     6241 aaattccatg ttaaatgacg gatatctcca gtcaacattc cgtaagtaat attatcagca
     6301 tagtttttct tagctgattt gtaggtaggg tcatttgggt aaagtcgtgc aacgctgaac
     6361 tcacccttgt caaagttctt gtagaacgaa cctgggtctg aaccatctga gtaagtcaat
     6421 ttaacagatt ctatcccaac attcttagca tcccagtagt tttcattttt atggaattcc
     6481 atagatgatt ttgaggtgaa ggcgctcaag aagtaagcac cattaacaag gattgatgat
     6541 ggatcggttg taccaaaatc tttacctttt gacttcaaaa atttcgcatt aactgggaaa
     6601 agcacactat aagttgtttt tgaattccag tagctttcag gcttgttcaa agtatactga
     6661 acagttttat cgtcaagggc tttgacacca acttctttaa aatctacttc accattttgg
     6721 taagccttta agttttttat tgaatcttca acaacgtaaa gagcatctga tttatcgtca
     6781 accgcgtgct tcaaaccagt cacaaaatct tctgctgtta ctggggcata ttcttcacca
     6841 tcagccgtat accaagagac accatcgcga agagtataag tataagtcag accgtctttt
     6901 gaaaccttcc aatctttagc aagtgatggt actaaattac catactcatc gttttccaaa
     6961 agaccatcaa ccatttgtgt tatcacatca gtcgttccac cgccattagt caaaatataa
     7021 tccaatgatt ttggatcgtt aacaaaaacg tacttgtagg tttttgtagc ttctgagcca
     7081 cctgaagcat ttttattacc acaagctgcc aaagcggata ctgacaagat cgcaacactt
     7141 acagctgcca accatttact tttcttcata aaagtcaccc ctaaacttta tttttcattt
     7201 tttggcaatt gctaaatgaa attggttaat tgaagacatt atatcataaa actttcttaa
     7261 agaaaataat gaaatgaaaa attatctgaa tatttcgtag aattttcttt attttataca
     7321 tttatctata tgaaagcgtt atactccttt tttaatgagg tttcaattag tttaataaag
     7381 attgtcattc tctcatggta gcgttttatt gcatcactac tcttgtgagg taagtcatta
     7441 ccttagacaa aaatatggta taattaaaaa aataatactt gagtaaggat aatctataaa
     7501 tgatcaaacg attaatttcc ctagtggtca tcgccttatt ttttgcagca agcactgtta
     7561 gcggtgaaga gtattcggta actgctaagc atgcgattgc cgttgacctt gaaagtggca
     7621 aagttttata cgaaaaagat actaaagaag ttgtcccagt cgcctcagtc agtaagctct
     7681 tgacaaccta tctggtttac aaagaagttt ctaagggcaa gctaaattgg gatagtcctg
     7741 taactatttc taactaccct tatgaactca ctacaaacta tactattagt aacgttcctc
     7801 ttgataagag aaaatatacc gttaaagaac ttttaagtgc gttagttgtt aataacgcca
     7861 atagccccgc tattgcttta gctgaaaaaa taggcggaac cgaacccaaa tttgttgaca
     7921 aaatgaaaaa acaattaagg caatggggca tttccgatgc aaaggtcgtt aattcaactg
     7981 gcttaactaa ccatttttta ggagctaata cttatcctaa tacagaacca gatgacgaaa
     8041 attgtttttg cgccactgat ttagctatta ttgccaggca tctcttatta gaatttccag
     8101 aagtactgaa attatctagc aaatcctcca ctatttttga tggacaaacc atttacagtt
     8161 ataattacat gcttaaaggc atgccttgtt atcgagaagg cgtggatggt ctttttgttg
     8221 gttattctaa aaaagccggt gcttcttttg tagctactag tgtcgaaaat caaatgaggg
     8281 ttattacagt agttttaaat gctgatcaaa gccacgagga tgatttagct atatttaaaa
     8341 caaccaatca attgttgcag taccttttaa ttaattttca aaaagtccag ttaattgaaa
     8401 ataataaacc agtaaaaacg ttatctgtct tagacagtcc tgaaaaaact gtcaaacttg
     8461 tagcccaaaa tagtttattt tttatcaaac caatacatac aaagaccaaa aataccgtcc
     8521 atattactaa gaaatcatcc acaatgatcg cacctctatc aaagggacaa gtcttaggta
     8581 gagcaaccct tcaagataaa catcttattg gacagggtta tctggatact cctccttcta
     8641 tcaatcttat ccttcaaaaa aacatttcta aaagtttctt tttaaaggtc tggtggaacc
     8701 gttttgtgag gtatgtcaat acctctttat agaataacac aatgcttttt gtatgacatt
     8761 gactgacaga gtacttctgc agtctttttc atttttattt aagcaaacta ggccaatcct
     8821 aacaattttt caaaaaaact tcacattgta ttagcaaagt gatatactga aaatgcatta
     8881 catttaaagg agtcggaaat tgaccaaaag aattatacta actattttta cctttatttg
     8941 cttttcggtg atgcctcttg tccaagccga agatgtcatg gatattacaa ggcaagcagg
     9001 ctacacagtt agtgaggtta atcgaccaaa atcttctatt gtcgttgatg caaatagttc
     9061 agatattctt tggcaagata atattgatat tcctagggat cctgctagta tgtctaaaat
     9121 gtttacgctt tacattttat ttgaagagct cgctaaggga aaaattacga tggacactac
     9181 tattacggca actccaaccg atcaagctat cgctaacatt tatgagatta gcaataataa
     9241 tatcgtcgct ggagtagctt atcctattcg tgatcttatt actatgacag ctgtgccttc
     9301 atcaaatgca gcaactgtta tgattgccaa ttatttatca aacaatgatg cttctgcgtt
     9361 tatcgatcgt attaatgcca cagccaaaca attaggcatg actaacactc atttttcaaa
     9421 cgctagtggt gcagcagcac aagcttttca aggttattat aatcctacta aatatgattt
     9481 atctgcttca aatattacga ccgctcgaga tttgtccaag ttactctatg ccttcttaaa
     9541 aaaataccct gaaattatct cctttacaaa taaatctgtt gtgcacacta tggtaggaac
     9601 gccatatgaa gaagaatttc acacctataa ccactctctc ccagacaatc aatttggtat
     9661 gaaaggagtt gatggattaa aaacaggttc tagtcccagt gctgctttta acgccatgat
     9721 aactgccaaa agaggcaaaa ctcgactcat tactattgtc atgggggtcg gagattggtc
     9781 agatcaaaac ggagagtttt atagacatcc tttcgttaat gccttgactg agaaagggtt
     9841 taaagatagt aagaccttat ccaaaaaagc acgccaaaaa ctcgaaaaat tagtgccaca
     9901 aaccaaaaaa gaaacatcac ctaaacagca gcacttcaaa gccactaaaa agcaatcgta
     9961 cttggaaaga gtcgaagatt ttatgaatca caaccacact ttcttgctta tttgcttagc
    10021 tatctttata attactatcc ttttactaag cctcgttgtc tttgcaatgg gacgccaata
    10081 atgaattatc aaaaacctct gtcaaagcac agaggttttt gatatgttat cttacgtgtt
    10141 caaggcaact aaaaactaac cacttggggt tagtactaca actcataaaa tcctatctca
    10201 aagatctttc agatggataa gagaaaatgc aattaaccga cagaaccttc catctcatag
    10261 gaaatcaatc gattgagttc gaccgcatat tccattggca attctttggt aaaaggctcc
    10321 acaaatccca tgacaatcat ctctgtggct tcgctttctg ataagccacg gctcatgaga
    10381 tagtagagtt gttcttcaga aatcttagac actttagctt catgttctaa cgccacctgt
    10441 gaattatgaa tttcgttaaa tgggatcgta tctgatttag aaatatcgtc catcaaaata
    10501 gtatcacatt caatatggga aacggatttt ttagattgct tgttaaaggt cacttggcca
    10561 cgataatcta ctttaccacc agacttggca attgattttg acacaattga tgatgatgta
    10621 tggggagcat tgtgaatcat tttagcccct gtatcttggt gttggcctgc gttagcaaag
    10681 gcaatagaca gcatggtgcc acgcgcacct ggcccatcaa ggtaaacaga agggtacttc
    10741 atggtggttt tagctcctag attgccatca atccattcca ctgttgcatc cgtaagggcg
    10801 cgtgcacgtt ttgttactag attatacaca ttgtctgacc agttttgaat ggtggtataa
    10861 cgcatgtatg caccgtcaag cgcaaagatt tcaacgatag cagcatgtaa gctgttactt
    10921 gaataagtgg gagctgtaca tccttcaaca taatgaacac ttgctccttc atcaacaata
    10981 atcaatgtcc gctcaaattg accagtattt tcattgttaa tgcggaaata agtttgcaaa
    11041 gggatatcta ccttgacccc tttaggaaca taaataaagg taccaccaga ccaaactgct
    11101 gaattgaggg ctgctaattt gttgtctgtt ggcggaacca gtttggcaaa gtattgtttg
    11161 aacaaatcag gatattcttt gagggcggaa tcggtatctg taaagataat ccctagcttt
    11221 tcaaattcac ccttcatgtt atggtaaacc acttctgact catactgagc tgatgcccca
    11281 gcaagataag cacgttctgc ttctggaatt ccaatacgat caaaggtttc ttttattttt
    11341 tctggaacat catcccaaga acgagctggc ttatcagatg ctttttgata gtaaatgata
    11401 tcatcaaagt taatatctga taagtctgct ccccaggttt gcatcggcat tttattaaag
    11461 gtttccaagg attttaaacg aaactccaac atccactcag gttcattttt ggcagctgat
    11521 agttcgcgaa ccactgcctc actcaatcct tttcctgtag aataaatggg ctctacatca
    11581 tcgtgaaatc caaattggta gtcccctaag tcaattggct ttggctctac tttctcattt
    11641 atatcagaca tttttccctt cctttacatt ttggtccgtg aggtgctgag cattggcact
    11701 tcgtttaatg gcttccttga gagcattcca agctagggta gagcatttga tacgctgtgg
    11761 aaattttgca actcctgcca acaattctgc ttcacctagc tctttttgag caggattttc
    11821 ctgtccttgt accatctctg aaaaaatatc agctaacgcg agtgcttctt ctttactttt
    11881 accaataaca gcatctgtca tcatgcttga tgaagctgtg gaaatggtac agccgttgcc
    11941 tgcaaaagca atatcttcaa ttttatcttc gtcaaactta acggtcaaag aaatcacatc
    12001 accacaagtc ggattattca gttgaacagc ctctacgcca tctagttgcc catgatgatg
    12061 tggacgtttc gaatggtccg ctaccacagc catgtataga tggttcagtt tagagagtgc
    12121 cattgaaaaa ctcctttgct tttagaattg cttcgactag acggtcacaa tctgccttgg
    12181 tgttatagat ataaaaactt gctctaacag ttgctggtac acctaaataa ctaagaagag
    12241 gttgggcgca gtggtgccct gctcttactg caacaccttc atagtccaag gctgttgcca
    12301 agtcatgagg atgcaaatca tccagattaa aagaaatcag accagatctt gcactaggct
    12361 ggcttggtcc atatatggta agcccctcaa tagcttctaa tttcggcaag acataggcta
    12421 ttagttctgc ttcatgcgca tgtatatcag ccatgcctag tctctgaagg taagaaatgg
    12481 ctgcgcttag cccaatagca ccagctatgt gaggtgttcc tgcttcaaac ttccagggca
    12541 attctttcca agtggcctct tgttcgtaaa caaaatcaat catttctccg ccaaattcaa
    12601 gaggctccac ttgattcaaa agctcttctt tgccgtaaag aacacccaaa cctgttggcc
    12661 ccaacatctt atgagctgaa aaagcaaaga aatcacaatc caagtcttga acatcaatag
    12721 ccaaatgtgg aaccgactgg gcaccgtcaa caacaaggta ggctccttta gcatgtgcca
    12781 gcttggcaat ttctttaatg ggattgatgc aaccaagaac attggagaca tgtactaggc
    12841 taacaaaacg tgtttttgtc gtcaatttgt ttgccaaatc gtccatgtca agttggccat
    12901 cttttaaata aacatagact aaccttgctc ctgttttttg acaggcttgt tgccaaggaa
    12961 tgatattggc atgatgctcc ataatcgaaa tcaacacctc atcttctggc gtcaagacct
    13021 gctctgcaaa ccgagcaacc caattcaaac tggttgttgt tcctctggta aagagcactt
    13081 ccttacttga tttagcatga ataaagtcag caacctgctg gcgactggcc tcatatttgt
    13141 gcgttgcacg ttcagccaag gtatgaactc ctcggtggac attagcatta tcttcttgat
    13201 aataggattg caaagcctca agaacaagcg ccggtttttg tgtggtggcg gcattatcca
    13261 aataaacaag gggttcatca ttgacttgtt gatttaagat ttgaaagtct tgtttgatgt
    13321 cttttgcgtc tagcaatact aacctctttc tttttggcag taggtcttaa cgattaagca
    13381 atttctcatc taaaacctta ataatctctt ggtggactga tggaatagga atttcagcga
    13441 taactgctcc taggaatcct ctaataacca atcgttctgc tgtttcttga tccagtcctc
    13501 gactcatcaa gtaatacata tcttcagggt caacctgacc gatagaagct gcatgacctg
    13561 ctgttacttc attttcatca attaagagga ttggattggc atcggctctt gcttggtcag
    13621 aaagcatcaa aacacggctt tcttgttgag catcagctcc cttagcgcct tttagaatat
    13681 gaccaatccc gttaaacgtt aaggtgccac gttccaaaat cacaccatgc tgtaaaatat
    13741 gaccgaccgt acgttgacca tagttggtca cgcgcgtgtc aataccttgt acctgacgac
    13801 cacttgaggc tgcaacaact ttcaaatcag cttgtgagcc ctgaccaatc aaatcactgt
    13861 caaaatcagc aatgacattg ccttcattca tcacagctaa ggcccaatca atgttggcat
    13921 ccttctctaa acgtcctcga cggctaatat aggttgtcac tgaaggacct aagcggtcga
    13981 tagccgagaa tttaatctgg ctgcctgctt gggcaatcac ttctacactg atattagcgc
    14041 tggtcttttg agtggcattg ccaatagatt caaaacgctc taaataggtg aacttacttt
    14101 cttttcctgc aatcactaga acatgcttgt taaaaggaac gtcactgtca ctatcttgta
    14161 agaaaatagc ttcaatagga gttgtgattt ccaagtgatc aggaacgtag agcacggctg
    14221 cgctattaaa ataagcagtg tggtaggcag ctagtttgtc ttcatcaaaa gctaatgcct
    14281 gaccaaaatg agcttcaatt acttctggga tttcctcaag cgccgtataa aaatcactga
    14341 aaacaactcc cttgtcaatt aacgccattg gtaactgttc taagactgtt tgcgtgccta
    14401 cctgaacaag ctttgggtta tctccaatag ctataaaatc tggaacacta gctagacttt
    14461 cattttctgt taaggtacca tctcctagat tccaacggtg aaatttaacc ctttcgatgg
    14521 ttggtaactc taattctggt atggcttcta atgccgctaa acgccgttct tgcagccaag
    14581 caggctcagc gtgggcttgc gaaaaagcta ctagtttttc ttttgtcatc tgtcaatcct
    14641 ttgtctctgg tttttaaatt ggctgggtat atagaacatc acctagcttt ttgtagaaag
    14701 ctaaagtaat tgtctccaaa aacttaactt tcttccttat actcgattcc cagatcctgt
    14761 gcaatacctg cgtagccttc tttttcaaga cgagtagcca aggcagcatc accagataag
    14821 acaatacgac catccatcat aacatgaact aggtctgggg taatgtaatt caacaaacgt
    14881 tgatagtggg tgataatcat agctccaaag tctttcccac gcatctcatt aaccccttta
    14941 gagactactt ttagggcatc aatatcaaga ccagaatcaa tttcatctaa caaagcaaat
    15001 ttaggctcta acatgagcaa ttgaagaatt tcattgcgtt ttttctcccc accagaaaaa
    15061 ccttcattga ggtaacgctc tgccatctct tctttcatac ctaacaaagc cattttctca
    15121 tcaagtttgg tgataaaatc tcgcacggaa atcttatcct tatctgcctt accggcattc
    15181 attgctgcac gcataaattc agcgttggta atccctggaa tttctgaagg gtattgcatg
    15241 gcgagaaaaa gtcccagtct cgcacgctca tcaacttcta gatcgagaat attgaccccg
    15301 tcaagcaaaa tttgcccttg ggtcacttcg tagttaggat ttcccataat agctgctgaa
    15361 agggtagact ttcctgtccc atttggcccc ataatggcag ctacttcccc agttttaaga
    15421 gttaggttaa cccctttcaa aatctcttta ccttctattg aaacatgtaa attattaatc
    15481 tcaagaattg acatgataca ccccttattt tctctgtcat ctataccatc tcaagaaaag
    15541 acagtgtcat ttgcactgct ttttttataa tggtcactgc atctattata gcaaaaaaag
    15601 ccttactcgg cttttttagt gtttcaaatc cttcttttct ttccatttca gaagcattgc
    15661 ttgacgataa tcactattac caataaactt taacaagtta aacaaaggcg ttcgcttttc
    15721 accccagatc tccaatcctt caataaaaac ttctaaacca aataaaagtc caagcatcaa
    15781 gaggacgcca ccaattcgac tagaaacatt taaaagtaaa gaaataaggg aaaaaagcat
    15841 ggtaatacca taaactacta agacagctcc tcgatgagta aagcccattg ataagagtcg
    15901 atgatgcagg tgcatcttat ccggctcgta gaatttttga cctgataaac tacgtcgaat
    15961 aatagccacg atggtatcca taatgggtac accaagaata ataacaggtg tcaccacagc
    16021 cacagccgtt gaatttttca atccttgaag agacaaaacc cctatcataa agccaataaa
    16081 gagggctcct gtgtcaccca aataaatcat agctggatgg taattataag gaaaaaatcc
    16141 tgcaatagca gaaatcaaga ccaaaatggt taacgtcaaa aagaaatcct tttgaggtaa
    16201 aaagaaataa gatacaatag ccatggtcac taaactaata atagagaccc cactaaccaa
    16261 accatccaaa ccgtcaatca agttaatagc attagtgatg gaaacaatcc acaggactgt
    16321 taagaataag gttaagaaag gaccaaaaac taacaacggc cctccaaaag gaattttgaa
    16381 gctatcaaat ttaaagtcgg taaaagccca gacaatcact gcaccaatta gaataccaaa
    16441 catctttaat ttaggactta actcatacaa atcatctaaa aaaccagtaa gggtaattac
    16501 tgtagcacca atcacgacag gtaaaatata actgaagtag gtctgaccaa aaaacatggc
    16561 gcctttagaa gcaatcggaa taagtcccaa acttgctact aaaaaagaca taaaaatagc
    16621 taatccacca ctggttggca tcggaacctt attgacccgt ctggcattgg gattgtctac
    16681 tgcacccaca cgaaaggcta aaaagcgaac aagaggggtt aagaataagg acattaacaa
    16741 agcccctatc agaacaagga cataatctat tgtgaatgaa aacatactat tttatcccaa
    16801 ctcaatcttt tgtaattgct caacagcacc atcaagcatc aattgtaagc catgctcttg
    16861 taaataagct cttgtttttg atccagggtt tgcatgctca atcaatctcg catacatgac
    16921 attcgcaaaa taagatggtt gttgctgaac atctaataaa atagtcatat ggtagcagtt
    16981 gctcccctta tataactctg aagcttctat cgaaaaatca atcgttttag caaaagccac
    17041 tgcctctgta atcgttgaaa aatccaatac ataatggaca tagtctaaag gttctgactc
    17101 atgattagtt gatggatcag ccgcctcaga ctgattagct agagtagctt caacaacatc
    17161 ttccattatc tcttcaattt tttccaattt ttcatgagct ttgacatctc ccttttcacg
    17221 catggattgc tccaagctct tgaaaaaatc ttccggagtc atttgggaca tatcaccaaa
    17281 ctctgctaaa tcttcaagat taatatcttt atttatctca gatttggtaa caaaaacatc
    17341 tagacggtcc ttgcgtggag tcactcgaaa actaagcata ccactatctt taaaattatc
    17401 tggaagatcg agttcgtcca tcacagaata gaaaaactct tctgtttttt cttgaggaat
    17461 caagaaatct ttcaactcca ttcctctttc ttctaaatcg tccatactaa ttgttatttt
    17521 tagcgttgtc tcgctaattt gtttcatttc cattctcaat acctcgcacg cgtagtcatt
    17581 ttattatact agaaatgctg taatttcgca atttatgact aactcctctt ctccaaaagg
    17641 aaatttaaaa agcgacagtc cccaaggtct gtcgcaacat cctaaacgat atgtaagttt
    17701 aaaaaacaaa tttaaagaag ctataaataa gtaaaaggct tcctaacaca atacggtatt
    17761 tcccaaaaat ggtgaaatcg tgtttcttaa cataatctgt caagaaccta atcgccaata
    17821 aactaaccac aaaagcggtc aaactagcca ctaaaagaat aaggacttgt gcaaaatcaa
    17881 ggtgatggcc atcaaggaaa aatttcacag cctttaatcc actatatcca aacatggtag
    17941 gaatggccaa aaagaaggtg aaatcagcgg ccactgttcg actagttcct aaaataatag
    18001 ctcctaagat ggtagcccct gatcgactag taccaggcac aatacttaag acttgaaaac
    18061 aaccaatgaa gaaagctgtt ttgtaagaca ttctagctaa ttcagtgacg gcaggttctt
    18121 gttgagcatt tcgtttttca atccagataa aggcaatccc gtagacgatt aaagcgatgg
    18181 caatcggaac cataaaataa aaatgtgctt caaaccaatt atcaagagga accgctatta
    18241 aaatagaagg aatacacgca atcaccactt ttagccataa ttgccaggta agctgtactt
    18301 ctcttgctgt tttcccaggt tgaaagggat tgagacgttc aaaataaatc aacataacag
    18361 cgataatcgc ccctaattga ataacgatat taaacatttc tataaaagcc ttatcctgat
    18421 ttagtcggat aaattcctgc accaaaatga ggtgaccagt gcttgaaact ggtaaccatt
    18481 ctgtgattcc ctcaatgatg ccaaagaaaa tggcttttag caattcgata attaacatgt
    18541 tttctcctta ttaaccactc ttattgtgat tttctaaact gtgattaatg ccaagcagct
    18601 tttttaaaag gcaccgccgc cgcctcctcc gccaccgcca gagaagccgc caccaccact
    18661 aatcccgcct ccggaagaga ctgagaaatt tgaggaagtt gtagctgaag acaagctaga
    18721 caaaaaggtt ggtgtcgtag catacattac cattgataat tcacccggtc gaacagcttg
    18781 gtaaacctca ggtaaggcaa tacgatggac tttcaaatag cgttccactt tcttagcgta
    18841 accaaataag gtggcataaa ccaaaacacg gttccaaaca accaaacctt caatagcaac
    18901 atcctcaaat ttgtcaatgt ctcgtatcat gtttttaaag ctctgccatt gatgtaaccg
    18961 aacacccccc tcaggtgttt caatacccaa tttcttgtat tgatctaact tcaggctaat
    19021 gtaaaagcca aggcacatcg ttagcaccat taaagcaagg taaatgaggg ctaacccact
    19081 ttctttaata gccaagtaaa tcaataaacc actatttaga acaagcaaca aacaacctaa
    19141 tccctggaca ctattgcttt ttcgtttctc tgccggggtc atttgacgat aagtatctgg
    19201 taagtttaac tttttgatag tttctaggac attgtttgta atagctgccg acgctttttt
    19261 catcgcctta atcacctgct cagacgattg acggacttct tgctcgagct ttttaccttt
    19321 gtacgttttc tttaattgtt taatggtatc agcatcataa tggtattgac taaacaattg
    19381 atccaccggc aatgtcacct tgtttccaaa agccatatct aagaaggcag cttcctcatc
    19441 tgtcacacga tctaactgac tgatttcaag ataagctttc ccttcttctt tcgttaataa
    19501 aagcaccttt tggtcgatca gatccaacaa ggtagcttga acaagggcct caaaggtcac
    19561 tcctttaggg atcaataatt tctggctttc tgatgctgta ggggataaat aggcaaaact
    19621 ctgtccataa atcgcttgtg tcaacacaag aggcgaaaga tcttcaggga cttcgtaact
    19681 gtgatctgta tggttggcca aatgataacg attgaattgt ttctttaatc ttataaactg
    19741 tattaactgc cacagaagaa aacctacctc taccagagga atgactttgc caaatagcag
    19801 ctgtaacaag gcccttcgtc tggaaatctt agtttccaac gctacaattt tattcttttt
    19861 actcgttgaa acatcaactg gttcttctcc caataatgct tttttatccc aataagcatg
    19921 caattccaat tgccctgaga catttttggc attaatctga tagcgactgt taccttcttt
    19981 taacacttga ggtttctttt ggtaatatcc tctgtgagcc catagattag aatcctgaat
    20041 atcagttggg gtagtgacgg tcaaactcac cttttctaat gttttgtccc aatcactaat
    20101 cggtgtccaa ttcagctctg ccacgtcttg ataagctgtt aaaaggtggt gcagttgcca
    20161 gataacctta acgtcaacct tatcaccagc ttggccagca ttataaagtt ttaaacgata
    20221 gccatctcca aggtcactaa actcttgact aacaggtacc tgttgaccat tctgatatac
    20281 ctcaacttta ggcttttggt caatagcaaa gcccgctggc aaatgacctg cccggcccag
    20341 cgaaatatac tggccgttat aagaagtgtc aaattgatag gttacttttt gctcaaaccg
    20401 agcagtattt tcttttgata acagtaactg accttcatag ttggtgatgc tatagtctac
    20461 atcagctgct tttattcgta tccctaaaag actgaagcag agcacaagcg tcatcaaaat
    20521 ttttttcatg gcaacatcct ctttctgccc tcattttacc atattttaag gagatgacaa
    20581 aacctaaacc aagtccttca tcttattttt aatcattatt ttgaatattt ttccatattt
    20641 caacctattc actgataata tattgaaata ggatgcaaat tgctgtaaaa taggtctgaa
    20701 tactattttt gaaacaggag acctatatga aaaagctaat ccttagctgt ttggtcgcct
    20761 tggcccttct gtttggagga atgagccggg ctcaagcaaa ccaatattta agagtcggaa
    20821 tggaagcagc ctatgctcct tttaactgga ctcaagatga cgcttcaaac ggggctgtcc
    20881 ctattgaggg aactagccaa tacgccaacg gttacgatgt ccaagtcgct aaaaaagtcg
    20941 ctaaagctat gaacaaagaa ctgttagtcg ttaagacctc ttggaccggt ttaattccag
    21001 cattaacttc tggaaaaatc gatatgatcg ctgctggtat gagtcctacc aaagagcgta
    21061 gaaacgaaat tagcttctca aacagctact acactagcca acctgttcta gtcgtaactg
    21121 ctaatggcaa atatgctgat gcaacaagcc tcaaggattt ttctggagct aaagtaactg
    21181 cccagcaagg cgtttggcat gtcaatctct taactcaact aaaaggtgct aagttacaaa
    21241 caccaatggg agatttctct caaatgcgac aagcccttac ttcgggtgtt atcgatgcct
    21301 atatttctga acggcctgaa gccatgactg ctgaagctgc tgatagccgt ttgaaaatga
    21361 tcactcttaa aaaagggttt gctgttgctg aatcagatgc tgctatcgct gtcggaatga
    21421 aaaaaaatga cgatcgtatg gcaactgtca accaagtgct tgaaggattt tctcaaacgg
    21481 atcgtatggc cctgatggat gatatggtta ccaaacaacc cgtggaaaag aaagccgaag
    21541 atgctaaagc atcatttcta ggccaaatgt gggctatttt aaaaggtaac tggaagcaat
    21601 tcttacgtgg aactggaatg acccttctga tttccatggt cggaaccatt acaggtctct
    21661 ttattggatt attaatcggt attttccgta cagctcctaa agctaagcat aaagtagctg
    21721 ccttgggaca aaaactcttt ggttggttac tcactattta catcgaaatc ttccgtggga
    21781 cacctatgat tgttcaatct atggttattt actacggaac agcgcaagcc tttggtattt
    21841 cgatcgaccg taccctagcg gctattttta tcgtatctat caatacgggt gcctatatga
    21901 gtgaaattgt tcgcggtggt attttcgctg tcgacaaagg tcaattcgaa gcagcaactg
    21961 ctcttggctt tactcacgga caaaccatgc gtaaaatcgt gctaccacaa gttgttcgca
    22021 acattttacc agcaacaggt aatgagtttg tcatcaatat caaagatact tctgttttga
    22081 atgttatctc tgttgtggaa ctttacttct caggtaatac cgtagccaca caaacctacc
    22141 aatatttcca aacctttacg attatcgcca ttatctactt tgttcttacc ttcacggtga
    22201 cacgtattct tcgtcatatt gaacgccgtt tcgatgccga tacttacacc actggagcaa
    22261 accaaatgca gattgcggag gtctcaaatg tctaactcaa ttattgaaat caaaaacctc
    22321 aaaaaatctt acggcagcaa tgaagtactc aaagatatct ccctttctgt taacaaggga
    22381 gaagtgattt ccattatcgg ttcttctggt tctggaaaat caaccctcct gcgctcgatc
    22441 aatcttttgg aagagccaag tgccggtcaa atcctctttc atggtgaaga tgtccttgct
    22501 gaacactaca acttgactca ctaccgtgaa aaactaggca tggttttcca atcctttaac
    22561 ttgtttgaaa acctaaatgt attggaaaat gctatcgtcg ctcaaaccac cgtcctcaaa
    22621 agagaccgtg cacaagccga acaaatcgct aaagaaaacc tcaatgcggt tggtatgaca
    22681 gaacaatact ggcaagccaa accaaaacaa ttatcagggg ggcaaaaaca acgggttgcc
    22741 attgccagag ccttatctgt caatccagaa gccatgctct ttgatgaacc aacatcagct
    22801 cttgatcctg aaatggttgg tgaggtcctt aaaaccatgc aagacttggc aaaatcaggg
    22861 ttgaccatga ttattgttac ccatgaaatg gaatttgctc gtgatgtttc tgaccatatc
    22921 atcttcatgg ataagggatt gattactgaa gaaggaagtc ctcaacaaat tttcgagaat
    22981 cctacacaag atcgtaccaa agaattttta caacgcttct taaaataaga taaaggatcc
    23041 aactatttct atgccagttg ggtctttttt caattcaaaa agaatttgtc ataaaatact
    23101 ttaccagtta actattttat gctatactta tttttgttaa cgttaataat ttatatttag
    23161 gaggataata tggcagaaaa aactgactta tcgtcagctt acagaagact gaaaagtccc
    23221 aatattaaaa ccagaaaacg tgctctgaag attattcacg agtacaaacg ttacggtaaa
    23281 aaataagatt ttacttttta tctctccaaa tttaagtcag acaaaaaaag gctaagacac
    23341 cccttccatc ttagcctttt tgtatacagt ttattaaggg aactatttta aaatatcttt
    23401 tatgctagag tctagaatag ttcaaaacgt taaaatcata catttaaggt agtgtttaaa
    23461 gtatacgaaa aagaactcag cataaaccaa gctctctttc gttataacta attatttagc
    23521 aatttttgcg aagtactcaa gagtacgtac aagttgagca gtgtaagaca tttcgttgtc
    23581 ataccatgat acaactttaa ccaattgtga tccgtcaact tccattactt tagtttgagt
    23641 tgcgtcaaac aatgaaccgt atgatacgcc tacgatatct gaagaaacga ttggatcttc
    23701 agtgtaaccg aagctatcgt ttgaagcagc tttcatagca gcgttgattt cgtcaacaga
    23761 aacgtttttg tcaagagtta caaccaactc agttactgat ccagttggaa caggaacacg
    23821 ttgtgcagca ccgtcaagtt taccgttaag ttctgggata acaagaccga tagctttagc
    23881 agcaccagtt gagttaggaa cgatatttgc agcaccagcg cgtgcacgac gaaggtcacc
    23941 accacggtgt ggtccgtcaa ggatcatttg gtcaccagtg taagcgtgga ttgtagtcat
    24001 aagacctttt tgaataccga atgcatcgtg aagagcttta gccataggag ctaaacagtt
    24061 tgtagtacat gaagcacctg agataactgt ttcagtaccg tcaagaatgt cgtggttagt
    24121 gttgaaaaca actgttttaa catcgtttcc accaggagct gtgataacaa cttttttagc
    24181 accgttagca tgtaagtgtt tttcagctgc ttctttttta gcaaagaaac cagttgcttc
    24241 aagaacgatt tcaaccccat cagttgccca gtcgatgttt tctggatcac gttcagcaga
    24301 aactttgatg aagtttccgt ttacttcaaa tccaccttct ttaacttcaa ctgttccatc
    24361 aaaacgacct tgagttgtat cgtatttcaa caagtgtgca agcatatttg gatctgtaag
    24421 gtcattgata cgagttactt caacaccttc gatgttttga atacggcgga atgcaagacg
    24481 tccgatacga ccgaaaccat taataccaac tttaactacc attagtgatt tcctccttat
    24541 gaaaatcaaa agaatattat ttagagggaa tgctccctac ctattgtgaa aagattaact
    24601 tacagtcatc tgcaacaacc tttcaacaga actattatat aactatttca gaaaaaatgc
    24661 aaataaatta gccattttca taaagggcag cttctttctt ctagccttca aaacccacca
    24721 aatataggaa agggctttct tttttctatg ttctattctg taatttatct ttttattggg
    24781 aaagatttcc aaaacttcaa actgtactat aacgttctgt tacactaaaa aagaggttag
    24841 gatagttatc ctcaacctct tagtggtggt tattcacctt tgtttttctt aatgatttct
    24901 tcttgaactg acttaggaac atcttcatag tggtcaaata ccatcatgaa tgtaccacgt
    24961 ccttgagtag cagaacgaag aactgttgca taaccgaaca tttcagcaag tggaacataa
    25021 gcacgaacga tttggctgtt accatgtgct tccataccgt caacgcgtcc acgacgagct
    25081 gtcacgtgtc ccataacgtc tccaagattg tcttctggag ctgtaatcgt tacaagcatc
    25141 atcggctcaa ggatagctgg ttgtgcagat ttagctgctt ctttaagtgc aagtgatgca
    25201 gcgatcttga aggcagtttc agatgagtcg acatcgtggt atgaaccatc gtaaagctta
    25261 gctttaacat caaccattgg gtaacctgca agaacaccgt ttgccataga ttcgatcaac
    25321 cctttttcaa cagctgggat aaattcacga ggaactacac caccaacgat agcattttcg
    25381 aattcgaaac ctttaccttc ttcatttggt gtaaattcaa tccaaacatc accgaattga
    25441 cctttaccac cagattggcg tttgaagaat ccacgagctt gtgtagaagc acggaatgtt
    25501 tcacggtaag atacttgagg agcaccaacg ttagcttcaa ctttgaactc acgtttcata
    25561 cggtcaacaa ggacatcaag gtgaagttca cccataccag cgataactgt ttcaccagtt
    25621 tcaacgtttg tttcaacgcg gaatgttgga tcttcttcag caagtttttg aagggcaaca
    25681 cccatcttgt cttggtctgc tttagatttt ggctcaacca tcaactggat aactggttct
    25741 ggaacttcga ttgactcaag aataactttt gctttttcat cagtcaatga gtcaccagtt
    25801 gttgtgtctt tcaaaccaac agcggcagcg atgtcaccag cgtaaactgt ttcaatttct
    25861 tgacggctgt ttgcgtgcat ttgaaggata cgtccgatac gctcacgttt accttttgat
    25921 gtgttcataa cgtaagaacc gctattaaga acacctgagt aaacacggaa gaatgtcaaa
    25981 cgacctacga atgggtcagt catgatcttg aaggcaagag ctgcaaatgg ctcttcatca
    26041 gatgctggac gttcttcttc agcatctgta tccgggttaa cacctttgat tgcagggatg
    26101 tcaagtgggc ttggaaggta tgcgataacc gcatcaagca tcaattgaac acctttgttt
    26161 ttgaaggcag aaccacaaag tactgggaag aattcaacgt tgattgttgc tttacggata
    26221 ccagcaatca attcgtcgtt agtgatttct tcaccttcaa ggtatttcat catcaagtct
    26281 tcatcagttt cagcaactgc ttcgattaat ttttcacggt attcttgagc ttgttctaag
    26341 tattcttctg gaatatcttc ttcaaggata tctgtaccaa ggtcgttggt atagatttct
    26401 gctttcatct tgatcaagtc aatgatacca cggaaatcat cttctgcacc gattggcaat
    26461 tggattgggt gtgcatttgc ttgaagacgg tcatgaaggg tttgtactga gtaaaggaag
    26521 tcagcaccga ttttatccat tttgttggcg aaaacgatac gtggaacacc gtattcagtt
    26581 gcttgacgcc aaactgtttc agtttgaggc tcaacacctg attgtgagtc aagaacggtt
    26641 acagcaccat caagaacacg gagagaacgt tgtacttcga tggtgaagtc cacgtgtcct
    26701 ggtgtgtcga tgatgttaac gcggtgacca tcccattgag ctgttgtagc ggcagaagta
    26761 atagtgatac cacgttcttg ctcttgctcc atccagtcca tttgtgatgc gccttcgtgt
    26821 gtttcaccga ttttatgaat tttaccagtg tagtaaagga tacgctctgt tgtagttgtt
    26881 ttaccagcat cgacgtgagc catgataccg atattacgag tttttgcaag tgaaaattcg
    26941 cgagccatgt gtttctccta tttttttagt ttactctttc attatagcac tatttagcaa
    27001 aaacggatag gcaggaccta cccgttatct aaatatttgt tggtaaagat aatacctatt
    27061 gcctttataa ggcttggtat cttattcatt gaactcaggc taaacgctgt gtgaaaaaga
    27121 taaactttcc tagagacaaa ggtttcttcg tcaaatttcc tattttcact ttgcgttcta
    27181 tacgccttcg tatcttatta attgagttcg agctacaagc cactgacaaa aagataatag
    27241 ttcctagaaa ctgaagtttc tgcgtcaatt tccctatttt gtctagcatt tgtttgacgc
    27301 taaaatatct tatattacca acggaagtga gcaaaggcac ggttagcttc agccattttg
    27361 tgagtgtctt cacgtttctt aactgatgca cctgtgttgt ttgcagcatc catgatttct
    27421 ttagcaagac gatctttcat agtgtgttca ccacgagcac gtgatgcgtt taccaaccaa
    27481 cgaagtccaa gtgttgtacg acgttctgga cgaacttcaa ctgggacttg gtagttagaa
    27541 ccaccgacac ggcgtgcgcg tacttcaagt acaggcatga tgttgtccat agctgtttca
    27601 aatacttcaa gagcgtcatt tcctgttgct tctttgatag cgctgaaagc atcgtaaacg
    27661 atagtagcag ctgtaccacg tttaccgtca agcataacac ggttgataag acgtgttacg
    27721 atttttgagt tatataatgg atctggtaat acttcgcgtt taggcgcttg atttttacga
    27781 ctcattttct cttatccccc ttctattatc cttttggacg tttcgcaccg tatttagaac
    27841 ggccttgttt acggtcagca acacctgcag tatcaagtgc gccacgaacg atatggtaac
    27901 gtacccctgg aaggtctttt acacgtccgc cacggataag aacaacgctg tgctcttgca
    27961 agttgtgtcc gatacctggg atgtaggcag ttacttcgat aaggttgctc aaacgtacac
    28021 gagcgaattt acgaagggct gagttaggtt ttttaggtgt cattgttcca acacgagtag
    28081 caacgccacg tttttgtggg gcagccattt tagtttgaac ttttttgtga ctgttgtaac
    28141 caatgttcaa agctggtgaa tctgattttt caattttaga tttacgtggt ttacgtacca
    28201 actggttaat tgtaggcatc tacattctcc tgtgtttttt tatttttggt tgatatagca
    28261 cttggtgaca gcccatatcc ggtgcacttt ttgcaacaat tgtcagcacg tctctgtaca
    28321 cttttgagag accaaaagta aaaagtaccg tctaatataa taacacagac ggtacttcat
    28381 gtcaaataga atttttcctt tgatgcaatt gcttatgacg aatgcatcac ttagattcct
    28441 tacggaacct aaatcctgtg aggccgacag ctgccaacat gacgactcct gctttaagag
    28501 ctctttgagt actttcatca acatcagaaa tgagattgct cgttgtagaa gatcctgagc
    28561 cataagatgt cttagatgag ggctgagtaa tcgaagatgt gattttagac acaatggcat
    28621 tacttgctac catttcagag gtttggccaa caagcgcttc tgctacaaga cttgtatttt
    28681 cagcagctaa tcttgctgaa gcttctaata gttgtttcgt ttctttaacc atttcttgaa
    28741 caagcggagt agtatctatc ttactatatg atagcggttt tacgcccgta agaggtggag
    28801 ctacttgcaa atcaggcaca gtagctatat cttcgtctaa atggcgatat cccttttcat
    28861 tagctaaggt tttaagcaaa gtcaactggt gttctgtggt agcaatagta gcttctagac
    28921 tgctttgttt agcttgtaag gctgctaaag tttcttgtgc atttaacaaa gatgaggtag
    28981 ttttagctaa atcttgctta gtattatcaa tgcgctcacg tatcacttga aggcggttag
    29041 gattcaattt aaagtccctt agatattgca aatgagcttt tttagccacc agtgctgtca
    29101 ctctggctgc ggcttgctct gctaagactt ctgtctggtg cagtgcggct ttcaacgatg
    29161 ctagcttagc taatgattga tcacgagtag cttcgagttg tgcttgtttt gctttagctg
    29221 ctagtaattc tgttctcaaa gaacctttag tatcatttaa ttgtctcact tggaggttta
    29281 agctgtctga ctgcttaagt gtgcttgcta atttaccttg aagttgactt actttagctt
    29341 gggctgccat aatgtcagct tcttgatgaa tagccgacaa acgattttct aatgagctta
    29401 cttttccttt gatcgctgca atagtatcag atacagtgcc tactctttgg gcataatctt
    29461 ttgtacttcc aacggctttt ataggggtct tattaaagcg ttgatggtta gcaatgttag
    29521 actctggaaa cattacaaag tgttcattca aagatcctac attgctggtt gaaaatccaa
    29581 ggtaaacagg cgcattaggg ttacgtttat ctacacgtaa aaagttaata gcatggccgt
    29641 atgtatttcc gtgtaaatga tctgtaaaga gcatatactt gatactgtca taaataccac
    29701 gtttaatacc attcacagta tgcacatcgt taaaagcacc gatattctcg tacatgttat
    29761 catcatttcg aatgagccct gacgctccgg cagagtcttc aataatagtt ttatcatgag
    29821 gcccaacacc ataatgccct gatacccctg gctgtccgta gacaaatgat ggtcttgtat
    29881 taccatgagt tttcttatag ctggtactaa gtaatcttgc aaattcttgt gatcctgctg
    29941 taacagtaac tggtggtaga cctaattgtc ttcttacact attaatcatg tgagctgcaa
    30001 actgcgctag ctcattttgc acttctggtg tcaaattatc gggatcaaca aagcgattac
    30061 gatctgctgg aatatcttgg tattgattta attgattacc tggactagct ttggcaataa
    30121 tttgatctgc atgctctttg taataattat tgtaactagc tgatccaata taaccactag
    30181 cttctaattt tttaagttct tcaagaggat agccttgcgg tactttcatg gtattattac
    30241 ccacaatgct atcttgagta gacggagctg aggatttaag acgactaagt tctgcctctt
    30301 tttctgctag agcagctttc tgagctgcca actcttcagt caattgcttt ttaactttag
    30361 ctttttgatt ttctaagtca gctttagcct tctccaattc tgagcttaat gcttttgtat
    30421 tatcattagc cgtttgagct gctttagtga tagcatcagg attgctaatc atagcattga
    30481 gcttagcaat attttgttca gacgttttga cttgttccac taaatcttga gctcgagtag
    30541 tttctgctga aatgctagct ttttgttctg acaatgcagt ctcttttgaa tgttgatctg
    30601 cttgagcatt atgaagctct gtttcagtag ctgttaactc tctttgatgt tcggctcctt
    30661 gggctaatag cgtctcctca ctacttgcaa gagtattagt gtaaatttct tgtgcagagg
    30721 ttaaagcttt ttgttcatta tcttgctgct cttttaagtg gttgatttca gcagtagttt
    30781 ttgtcagagc ggtagcaagc tctgtcagtt ctgctttttg ttgactgaga gttttttcaa
    30841 ctgcatcaat agttgccttt gcctcttgaa ttgtttctgg ttttggtaaa ctatcgtcgt
    30901 gagtattact cgccttcgtt tctcctgagg ctctatcatc tgctttgact tggtgagata
    30961 cgcctacact ggcactcaat aaagcaattg ttgaggttaa agcaattttc tgcttaactt
    31021 ggtttggctt cgtttgttct aagtccattc tctctccttt ttccatttat cgaaaatatt
    31081 accaacttct acaacaacat tgttgttttt gacatcaatc tctgaaactt tcagcaatga
    31141 tttgaaggtc atttgctcac gctctgattg agcgttttct gcaaacacag caacaccaac
    31201 taaagtgctg tcaaattctg tcaagagact gatcattcct gtaatcgtcc ccccgccctt
    31261 caagaaatca tctacaatca atacacgact attgggtttc aaactacgct ttgacagaaa
    31321 catcttttca atacgatcac tagaagcact cgcataattg acagacactg tcgatccttc
    31381 tgttattttt aaatcacgtc taacaatgac aaaaggaaca cttaaaatat tagccactgc
    31441 atttgctaaa ggaactcctt tggttgcaac tgtcatcaca gcgtcaatct tttctccttt
    31501 aaaggcattg gcaataatac gaccaatatt ttgtaaaatt ttaggtgtac tcagcaagtc
    31561 tgacaaatag atatagcctc caggtaagat gcgatcactc tctgataacc tttgacacag
    31621 gtcttcaaca atggtacgcg cttctgtttc tgaaatactg ggggtaaaaa ttacgcctcc
    31681 acttgctcct gtaagtgtat cgatatcacc aatgttagct tcttcaaaag ctttcttgat
    31741 aatagcgata tcttctgaga tagaagattt tgcggcctca tatttagttg caaaggtgtt
    31801 taaactagtt aatttatacg gattgttaat caaataattt gaaatgacaa ccatacgttc
    31861 acttcgtctt aatttcatag tttccccatt tttatgtact ttttgctatt ataccataaa
    31921 gttaataaaa aacgaacatt cgattaggaa aatattggtt tttttgttct tattaatatc
    31981 atgcaagaat tcaatctaag ataaactaat caacattcct actgaaagga cattctactt
    32041 aataaccata acaagagcca aaaacactta tgaaaccatc ataagtgtta agcacatcaa
    32101 aaatcatcac aaaagcaaag taactattac ttgagaaaca ctgatcaata gtttggcttg
    32161 taaaaagacc gattatccat ggcaaaaatc cgattggtca tctcgccctc gctaacacgg
    32221 ctaagagctg ttgtcatcat catcatatta gcatcaatat tgtcaatcat atgaataatt
    32281 tcagcttcca tgatgcgtgg acgtaccgga ctaccgtatt ctaattgccc gtgatggctt
    32341 aaaatcacgt gcctaaggac aatgacttct tctttggtat catcgatttg tagttctgaa
    32401 attacttttg taatttcttc gttaatgaga gaaatatgcc caatcaagtt accacgaacg
    32461 gtgtattctg tattatctgg tcctgttaat tctatgactt tagctaagtc atgtaacata
    32521 atacctgcaa acagtagact cttatttaag tcagggtaga tatctccaat gctatctgct
    32581 agtctgacca tcgtagcagt atggtaggcg aggcctgact caaaagcatg gtggtttgtt
    32641 ttagctgcag gataagtata aaattcttta tcatacttac gataaagagc ccttacaatt
    32701 cgttgccacg ttgcattttc aattttaaag agcatctgtt ccaaatagtc acgtacttct
    32761 gtcacactga caggtgcctt ttctttgaag tcctttggat cattgggctc acctgggcga
    32821 acatttcgca aggtgatttg attaacctga ggggtaccat tatacacctc gcgtcgccct
    32881 ttcataaaca cgactttacc agcagtaaat tcttcaacgt tataaggttg ggcatcccac
    32941 agatttcctg aaatctcgcc agtgtcatcc tgaaaggtaa ggctaataaa atctttacca
    33001 gctcttgtct tacgaacctc tgccgactta atgaggtaga acccttcaaa aagctggtct
    33061 tttttcattt gattaatttt cattattttc ctcttctaat aagggcatgt tcaagagaga
    33121 ttttgttgtt tggtcttgat aagtttcaac ggtattcaag gctcgaacaa tggcatttgt
    33181 ccttgttgaa atgagctgat ccagcgtatt attagctgta ttcatttgct tttgagcctt
    33241 ggcaagcagg ccaccaaatt tatcgaattc taacttgaca ttgcccaaaa ttttactgat
    33301 gtcatcagca tttttttgga tattaagggt cttgaaacca acagataagg aattgagcaa
    33361 agcagacagg gtcgaaggac ctgcaaccac aatattttct tcccgacgaa ggctatcaaa
    33421 gaaagccgca tttctgacca cttctgaata aagaccttct gttggtaaga acataactcc
    33481 gaaattggtc gtctctgggg ggttcaagta ctttttatga atgtctttgg caaagcgttt
    33541 gatagctgcc agaagtgctt ttcggctagc ctcgatggcc agtttatcac caacttcgta
    33601 agcatcttct aatcggtaat aatcttcaag agggaatttt gagtcaatcg gtaggtaaat
    33661 ataaccgcct tgaccatttc ctgggagctt aatcgcatat tctacgcgtt cactagaacc
    33721 actaaccgtt acaaattctc tttcgtactg gcttgatgtc atgatatcct caatgatttg
    33781 gcctagttga agttcgccta aaatgcctcg tgttttggta ttggacaaaa ccttatttaa
    33841 agtacccaca tcttgagcca cgctacgcat ttctcccaag cctttattga cactttctag
    33901 ttgcttggat acagaatcga aagaggcgtg cagacgattt tttaaggttt cttccaattt
    33961 ttcttcaacg atctggcgca tttcctccaa acgtttttcg ttagattctt gcatattttt
    34021 gagcgattgg ttgacctgct ggttaatttc ttctaagcgt ttgtcagacc ggtccctact
    34081 atcagacaaa ctacggtgca agacgtcacg aatatctgtt aattgttggt aaaggtctgc
    34141 ttgttgtcgg ttcatcagct gtgttagctc taacaattgt tgcttgttag ctgtatccaa
    34201 ctggtaggtt atttggtcag acaaattatc cgcgttgcct tctagggttt gggcaagctg
    34261 atgttgaagg ccgttgactt tgaacaacag ataagcccct aaacctaaga gaaccaagac
    34321 caaaaggaac aagataaggt ccatactaac tccaatcttt actttgaata ataatcaagt
    34381 agccacttgg caaactaact gtaataggtt gatggataaa ggcattactg gaatagattt
    34441 tctttttgaa aaaattatct tgcgtcaact caaatttagc accagtaatg gtcaagtcag
    34501 cttctccttc tgccataaat gccacatagg tcatcccttc ttcttgatgg ataaggtgct
    34561 gacctgccgg gcggtaggta atcatatttt gttggtcacg caaggcgatt tgtgccataa
    34621 agggagcaat accagggtcg ctaggcaaga aaatattgga taagaggtgg tccattcgac
    34681 ccccaaaagc cccaaaaatg gtcacttccg cctcaggaaa acgagcaaag acctctttaa
    34741 gggctaattc cgtatccgta tcattttttt ctggatgagc agtaataaaa agctctgcct
    34801 tctcttttat atccgtaaac gctttttggg aaaccgaatc aaaatcacca acagccatat
    34861 tcaaaggaag cccattttct aataaaaata ggctccctct atcaataccg acaaaataat
    34921 caaaatcacg gctgatataa gagagatctc ctcccgcaaa aagagcaact ttagacattc
    34981 aaggccgtcc ttaaggtttg gacttggctc actaggtcac tggccttgaa aaggtaagaa
    35041 cctgccacaa agacattggc ccctgcttca taacaagcac gaatggtctt attgtctact
    35101 ccgccatcaa cctcaatgtc aaaggacaat cctttttcat ctcgccattt ggctacggta
    35161 gccacttttt ctaaacattc tgggataaag gcctgacccc caaaacctgg gttgactgtc
    35221 ataatgagga cttggtcaac taagtctagc aaaggttcta gggctgttgc aggagttcct
    35281 ggattaatca ctacccctgc tttcatgcca gctgccttga ttttttgaag ggctccatga
    35341 atatgacgag tactttctgt gtgaatggtc atgatatcaa caccagcttg agcaaaagcc
    35401 tcaacatagc gttcaggatc aaccaccatt agatggcaat caaagaccaa tttactgtgc
    35461 tttctcatac ttgccacaac atctgcacca aaactgatgt taggaacaaa ttgaccatcc
    35521 ataatatcaa tgtgaacgta ttcggcatct gtttcttcaa tacgagctag ctcagaagca
    35581 aaattagcat aatcagctgc tagaatagat ggggcaattt ttagagttga catggagtag
    35641 acctactttc ttttgataac ttttttatat gtttcacgac ggttttcaat ttcactgaga
    35701 aattgcaggt aatgctcata acgaactggc cacaactctc ccgtttcaag cgctgccttg
    35761 acagcacact tgggttcgtg ggtatgggta caggatctaa acttacactc atggctcagc
    35821 cggcgcagct ctggaaaagc ctcgttcaaa tcttcagcat tagcaatatc atagtctaat
    35881 gatgaaaaac ctggcgtatc cgcgattttt ccgccatggg tattgtaaaa actcacagct
    35941 cgggtggtgt gacgaccacg ccctagacta tctgagattt ctcctgtttc aagagccaat
    36001 tcgggggcga ttcggttgag aagggttgat ttcccaacac ctgtttgtcc cataaagacg
    36061 gtaattttat cagctagcaa aggcaacaat tcctcaagac tggtcacaaa atcgtaaccg
    36121 attgcctgat actgtcgacc aatagcctta atctcctcgg gactatctaa taagtccatc
    36181 ttagagatat aaaccactgg atgaatggct ttgtgttcaa gcaagatgag aaagcggtct
    36241 agaagattgc tgttaaattc tggttcttta gcagacataa taaccactgc ttggtcaata
    36301 ttgacgatag gaggtcttac caaactgttt ttacgaggat gaatcgctaa aatataacct
    36361 tcagagttgt cctctgctga gaaatccacg atatctccaa cataaggtgt ctcaccgcgc
    36421 ttcctaaaat taccacgcgc tcgcgtctga tatacctgtc cttctgactc cacgtaataa
    36481 aaaccagcca gagatttaat gattttacct tgcaactgtg ctcctttgcc ctactataat
    36541 aactctatta tatcagaaaa ccgctcccaa atcagcattt gactctaagt ttcactcgcc
    36601 ttaaaaaact gtcaagattc tctagaccac tggctatcat ttaggtcact gctttttaaa
    36661 aatagaatat tttatcaact aaaaatcaga tcactgatga tttttgaggt aggaaacgat
    36721 atgaatttta agaagacctt tgctatttac gaaaaagagt ctaaccgtac cgctatagtc
    36781 acgctcttgt taattgcccc ttttttccgg ggtattaaaa aaactagctc tgcactgcga
    36841 taccttaacg gccagcttca ataagaaaaa tccccctgaa ctgaacattt ctgttttgtc
    36901 tacaagggaa tttttttatt gtcaccggga gaaagctttt ataatccaac ttcttttaaa
    36961 gcatcagcta atttgccaaa atcttgaatc gacaaggcct caccacgaat agaaggcttg
    37021 atatctgcta gtgctagacc tttttcaagt ttagtcttga tgtcttcaga cttcccaaaa
    37081 tggctagtca agttattcca cagggtcttg cgacgatgga caaaactgag acgagatact
    37141 ctgaaaaaga aatcttcgtc cttaacctca atcaaaggct ggtcgcgacg caccattttg
    37201 aggatagcac tatcgacatt tggtgcaggt acaaagacgg tgcgcggcac aatgaaggca
    37261 accttggcag tcatgtaata ctgcaccgca atggacaagg aaccataagc tttagtgttt
    37321 ggctcagccg agatacgatc tgccacttca cgctgcatca tgactacaaa ctcttggaat
    37381 ggaattttgc tctcaatcaa gtgcatgaga ataggcgttg tgatgtagta aggtagatta
    37441 gccaccacct taatgggcaa atcaggattt ttaaactgct tgatttgggt ctgcaaatca
    37501 gcttttaaaa tatcttgatt gaccacttgc acattatcaa aatcgcgcaa ggtatctgcc
    37561 aaaatcggca ccaagcggtc atcaatctca aaagccatca cttcagcagc attttctgcc
    37621 aaaaattccg tcaaagcccc aattccagga ccaatctcga taacattgac attctgatca
    37681 atctcagccg tgtcaacgat tttctgtaaa atattggtat cggtcaaaaa gttctgacca
    37741 aaagatttct taaaggtaaa tccgtgacga tcaaggacag ccttggtcac gctataatct
    37801 gcaattctca tatattctct tctttttatg atcactttct ttttggcatt tgaaccacta
    37861 gcctaaactt ttttgccaag atacgccatt cagttaatgg ggctgttata ttttattgta
    37921 ctctttactc ctcatatgtc tccatcactt cttccacttc tgctagggta atgccaaata
    37981 attcgaggcg cttgagcagt tgtttgccgt tggcatagcc gatgcggagc ttttcgccca
    38041 agtattccct gcgtttacgg ctatctgacg ccattaaaag ccctagacga atcaggtctg
    38101 tttgacgaat gtcaaaataa gactcatcat catattgctg agtgacatga gcaagtgcct
    38161 tttggaggtc ctcaaaattg gcatgttcaa cccctaagga acggccctta ctcttagaac
    38221 tcggaaccgc ctcgtttcgg tttaaaaagg cgtgacgagc tgttggcaca gctgccataa
    38281 tgagcttacg aatgcgctca ccattataat ctgggtctgt caaaacaatg acaccacgca
    38341 agtcatttag gcggttaatc cgttctaaat cttcttcagt gatagcagag cctctggtct
    38401 cataggtatc cacctcgtaa aaacggcgaa ggttagccgt gtcgtccttg ccttctacaa
    38461 caagaacctc ttgaatatta attttttcag tcaagcttaa gtaccctctt tgcattagca
    38521 gtcgtttctt ttgcaacttc ttccacggtc attccccgta gctctgcgat tttatcaacc
    38581 acataacggg tataagctgt atgattttgt ttgccacgtt ttggaactgg tgtaagataa
    38641 ggggcatctg tttccaccaa aatcttatcc aaaggcaagt gctgcgctgc ctcttgaata
    38701 tcaagggcct ttttgaaagt gaccacacct gaaaaagaaa tcatcatgcc aagttcaatg
    38761 aaacgttcag ccatctctaa tgatcctgag taagaatgca tgatgcctcc acgagggcca
    38821 acaccagctg ctttgatgac ctcataggta tcttccaagg catcgcgggt gtgcaccaca
    38881 aaaggcaaat catggtcttt tgctaattgc atttggcgct taaaaacctc tatttgcacc
    38941 tctttggggt cctccatcca ataatagtct aagccaattt cacctaaggc aatgacttta
    39001 ggatgtgata attgagagac gatagactcc tcaactgctt cagaataaga tcctgcttct
    39061 gtcgggtgcc atccaatagt agcatacacg ttaggatact ggtctgcgag agcaagtgct
    39121 ccactaatag tggcctggtc aaagccaacc acattatggt aggccacgcc catttcttga
    39181 gccaaagtca attcttcagt ttcgtgtcct tgaaattctg ctacattcag gtgcgtatgg
    39241 gtatcaaaaa tagttagttt ttctacttta tttgtcatga tgttattata acataaagat
    39301 cttaaccaca tcagaaaact tggtgagaac ttctgccgtt taggttgatc gtaaaaccct
    39361 ttgctagctg acacttgtct attttctact tttttgacaa atgaccttta atagtcggct
    39421 cctacataag ccctcaaaaa tactacaacc tactcaaata aagtgggttg aacaaatctg
    39481 tatcacaaaa agggtcgcta ccttctgtta gcgatctatg ctatactagt agatagttaa
    39541 actgtaagga gtatgctttg ctatgcctaa aaaccaccgc ctaattacca aaatcgaagc
    39601 atcattggaa catatgacca gtttagaaaa agggattgct cattttttta ttacaaccga
    39661 tctgacacct caagagttga ccgcatccga gatagttaag cgactacaca tctctcaagc
    39721 cgccttgact cgatttgcaa aaaagtgtgg ttttactggt tatcgtgctt ttgcctttga
    39781 ttaccttcac agtcttcaag aatcacaaga gactttccaa tctattcact tagaattgac
    39841 aaagcgcgtg ctgatggact acgatgctct tattaataaa acctatgagc tcgttaatga
    39901 agaaaaatta ctgaacttag ccaagctgat cgatgcttct gagcgagtct atttctttgg
    39961 caaaggatct tctggactag tagcaagaga aatgaagcta cgctttatgc gacttggttt
    40021 aatctgtgat gcttattcag acactgatgg ttttacttgg gcaaatagcc tcgtcaatga
    40081 aaattgcctt gtttttggtt tttctttatc tggcaaaaca aactctgtca tcacagcact
    40141 tcatcaagct agtcagcgag gggccaaaac tgtcctctta acaacagata atcaaaccga
    40201 atttgacgac tccttagata ttattcccgt atcatcaacc caccaactac attatgggaa
    40261 tcgtgtgtca ccacaatttc ctcttcttat tatgatggac attatttatg cttacgtttt
    40321 agcgattgac aaaccgcaca aagaaaaaat cttcaaaaac actattattg acaaagaaaa
    40381 taacggcctt tagactacaa tagcaaaaag ggcgttgttt tctttttaaa gggtcgtcat
    40441 tcacctcccc cagtatactt aaacaagaac tcttcacgtc atatagactc acagccacta
    40501 agattagcta ctcgctaaat tattttcgat tttctcaaga gttataaatg aacaggatcg
    40561 ctcattcttt tgtttaaaat ggtagtaagc tcctaatata ccagcattat ttccatgact
    40621 agcaaacttc agctgagttt tcttggcaag actagaaacc aagtagctat caagagctgt
    40681 ctttaattta tcagctaaat agtctttttg caccatgatt ccgccaccaa gtaccaccac
    40741 atttgggtta acaacgtagc agatattagc aataccttgt cctaagtaat ccacctgctt
    40801 actaatggct gctatacaaa tcgcatcacc cgctttagcc tgctcaaaaa tacgacgacc
    40861 atcccattgg ctaatgtcat ccccataagc taaggccacc tcttgaacaa gagctgtggt
    40921 agatgccaga tcctgaaact gaccatctga caaatgaagg taaccaactt cgcaagctga
    40981 atgactacta ccatgaaaaa cttgggaatt aaacaataaa cagccaccga ttcccgtccc
    41041 aattgtcaag caaagagcca caggataatc cttggcactg ccagaaatag cttcggctag
    41101 accagcacag ttaacatcgt tttccacttc acacggtaac ccgaaagtct cttcaatctc
    41161 ttttttaaac tgagttccag catagttagg aatctgaggg ccggcataaa agatttctcc
    41221 cttatcagga ttaaccattc ctgcagaaga aatggccact ccagccagat ccatttggtc
    41281 ttgataggtc tttaccaagc ccttgacctt ttccaaaata gagggaccac ctttataagc
    41341 ctcagtggcc atttcctctt tttccaacag gtctcctgtt tcagaaatca agccatactt
    41401 gatagcagta ccaccaatat caattgctaa ataatgcttc atttgttatc ccctcgcatc
    41461 ttattaaaag gtttccttag cctgattaat cagagcagca gcccgttggc aaataaccct
    41521 atcttcctcg accaactcag ctaaaggtga tcgaacagaa ccaatatcaa gaccctcatt
    41581 aatacgaagt acttccttaa taaccccata catattgccg tgagcagaaa caaggacacc
    41641 gatagtctca ttaatagtat attgaagggt cttggccttt tctaaatcct tgtcaactat
    41701 aagttgattc agccttaaaa ataattctgg catagccccg taggtgccac caatgcctgc
    41761 agcagcaccc atcaagcgcc ctcctagaaa ttgttcatct gggccattaa aaacaatatg
    41821 atcgtctccg ccaatcgcac agaaggtttg aatatcctgc actggcatgg atgaattttt
    41881 aacgccaatc acgcgcttat tagccaacat agtcttataa aggcttgggg tcaaggcaac
    41941 ccctgccagt tgaggaatat tatagatgat aaaatctgtg tgaggagcag ccgaagaaat
    42001 cgcattccaa taatcagcaa ctgcatattc tggtaaccgg aaataaatag gcggaatagc
    42061 tgcaatggca tccacgccca aacgttctga atgagctgcc aattcaatac tatctttagt
    42121 gttgttgcag gcaacgtgat taataatcgt cagcttgccc ttagcgactg ccatgacatt
    42181 ttctaacacc aattgacggt caaaaacgct ctggtaaata cactctccag aagagccatt
    42241 aatgtaaagc ccctgaaccc ctttgtcaat atagtactgg gtcaaggcac gcacacgctc
    42301 agggctaata gctccttggt catcgtaaca agcataaaag gcaggaataa tgccttggta
    42361 tttcgtaaga tctgtcatag taatgtcctt tattcaatgt cattattaag tgggaatcgc
    42421 ctaagaaggg attccatgat aatcaagtag aggtaagtta ggctactgat gcccatagtg
    42481 gccagtagag acaagccaca aaataaggtt aacagggtta acggcaaggt aaaaaccaaa
    42541 aggccaatca ccactagaaa agcaaacgtc catgggaata aaattcctgc cagcagtaaa
    42601 cttcgcttaa agagtattaa aagaggaagc tcttttctga cggcctgagg ataagcgtac
    42661 aaaaagagta taactaccaa aaataaaaca gcaatgcaaa gtactttaaa cccttgaaaa
    42721 actaggcctg attggtttcg aattaagaaa agatctaaga cacaaatact cattatcaaa
    42781 agctcaataa gacctaggcg catcccactt ttaaaataat gtttaaaatg agagctataa
    42841 gtagtaacaa gctgactaac ttgaccttct cgccaatcca acaaactcgc atacaaagcc
    42901 attttagcaa ccccaatcgt tagaagggga aggcaggaca agacaaataa gagattaaac
    42961 acgagcaaat caaacagtgc tgcgctagcc ctcatccatt tactatcaag cttgaagaga
    43021 gagtgtaaaa gtccctgttt tttcgatgtc aaatcacaac ttcctttcta gaaatacgct
    43081 tacaaacaaa agctaattcc cctcttaaac gtttaacaca tgacttgctt cccatctgat
    43141 ttatctatgt atgcacctaa attaataagc aacctataaa ttaagcttag cgacacgctt
    43201 tatttagtct aacctttcac agcacccata gtaatgcctt gggtaaatga tttttggaag
    43261 acaagaaata ccgtcacaat aggcactgca gccatggcag cccctgccat aatcaagcca
    43321 taattagtag ccatttcagc ttgcatagtg gcaaccccaa gtgaaatcgt taaattttcc
    43381 cgagaggtta acatcaccaa ctgcataaaa taatcattcc aagtattgat aaaggtaaaa
    43441 attgctagcg ctgcaaagcc tggtttgaca atagggaaag ccacattgaa aaaggtacga
    43501 atttcgccac atccatcaat cttggcggat tccaataact cggttggaat attttctgag
    43561 aactgtttca taaggaaaac accaaatggc cagcccacaa gaggcaaaat aacagccgcc
    43621 aaagtgtcat ggattcccat aaaattaaca atccgcacaa gaggcactag aacaacctgt
    43681 tttggcaagg ccatagcagc aataaaaatc gaaaacaaaa gccgctgtcc ataaaaccgc
    43741 tttttggcca aagcatagcc agccaaagag gaagtgccac aaaccaagaa catggtcgcc
    43801 accgaaataa agacactatt ccacaaccat tttaaggctg gattttgcac taccaaggcc
    43861 ttaaaatttt caatagtagg tgcctttggc caccattgcg gtggaatcat aatggtatcg
    43921 gcttgagcct taaatgctcc tgtcataatc caataaaatg ggaaaataaa caaaatggtc
    43981 aagatgcata gaataacagt agtcagaaca tccgatgcgg ttagtttctt tttcgtcatc
    44041 ttaatatcct cctaatattc cacatcatta cctaaaattt taaattgagc aaagctgatg
    44101 attgcaatca tgactgccaa gaacacaccc attgtgttgg catagccgta ttcagagagc
    44161 ttaaaggctt tttcatacaa atagtacatg agggtactag ttgaataatt tggccctcca
    44221 gacgtcaaga gttgaatcaa agcaaaacat tggaaggaat taatggttgt tatgacagca
    44281 atatataagg ttgttggcag gagacttggc cacttgatat tccaaaacac ctgaaattct
    44341 gtggcgccgt ctacacgcgc agcttccatc aaagaattat caatatttcc catagcagca
    44401 atatatagaa taataggctg cccaacagat gtggttaata aaatagcaat aatagctaac
    44461 aaagcccagt gcttatctcc cagccaacta atgttttgtt caatcacatg agcatatttt
    44521 aagacataat tcaaaatccc tgacatcgga tcataaatcc atttccaaac caccgttacg
    44581 gcaacacttc cggtaacaac aggtagaaag aaaactgccc gataaaacga acgcgccacc
    44641 acatttttgt cataagtctt agccgccaca aagagggaaa agaaaactac aacaggtacc
    44701 gaaccaataa cgataatcaa cgtattgata agagatttca taaagatagg atcttgaaac
    44761 atcctagcat aattggcaaa accaacaaag gtaaaatccg tcatggaata attgaaaaaa
    44821 ctcgtcacaa agcccataat catcggtatc aagacaaaaa tcacaaagaa aaccaagacc
    44881 ggagctaaga aagcgtatga gatgagcgtc tctcgcattt ttaatttatt gacgttcact
    44941 tgaaatacct cttttttctg ttcaactttt ctaaaaagaa aagcttcttt ccagtgacca
    45001 tttgacatgt gcattgaaaa gaagccactt gttctgaaca cttattgtgt ttttttgatt
    45061 gtcttgttcg ctttttcagt gaaggctttc aaagcatctt ctggcttttc atcaccatta
    45121 gagacggctt gaaccattgg gaaccaaaga gttctcattt cagcaaaccc atcaatcgtg
    45181 ttgtagtatg gtgagtagaa ttttgtccat tcagcaattt tttccattcg tttgtctttg
    45241 taaagatccc cataagaagt tcttacaggg aaagcacctg tacgaacaac atttttaggt
    45301 ccccattctt tatcatcagc gataaactgg ataaatgtct tagaggcagc gactttttgt
    45361 tcatctttgt tattaaagac cgcaaaacca tttacgaggt attctagttc tggtttgcca
    45421 tcatctgatg ggaatgggat ttcaaggtaa tccactttac tagcttctaa caatttagct
    45481 tggatgccgg gttgtgcagg cgcccaaaga atggtaaagg aagtttggcc attcgcaaag
    45541 ttttgaatat cagctgaacc gtcgtattga gagccattca tcattaaacc atctttaatc
    45601 caattggaaa ttttagtcat ggctttaata gagttagcat catctgtggt gtatttggtt
    45661 actttgtcat cggtaatatg actactataa aggttagcaa agaaggcacg tggtccttgg
    45721 tcaccacctt gaccattagc aaagaaagaa cctgggttat atcctttgtc cttcaatgct
    45781 ttcaagactt tttcaaaatc atctgttgtc caaccctctt tcacaaggtc aaggacacca
    45841 gcatctttga gcattttttt attcaacgcc atgtagaatg gagcagagct gataggatac
    45901 atgtaagctg tatctcctgc ttttgaggct tgaatcaatt tgtcattgtt aacatctttg
    45961 gtaaactctt ctgtgaacaa gtcattcaag tcagccaatt tcccattttt accatattga
    46021 atgatacgac ctggagcatc aaagaggaca tcaggagctg ttccagcttc aatagcagtt
    46081 gtgattttct caggaccaga tgtaaaatca atggtttcca attttacctt gatttctgga
    46141 ttagctttct caaaggcagc aatcaatttc ttctcatagg ttcccacacc atcttcagct
    46201 ttttcttgcg tgaagaccgg gaaagcccac catgtgattt ctgtcttagc agtatcagat
    46261 ttacttgcac cagcctcttt ctggctcttt ccgccacaag ctgctagtcc taaaacagat
    46321 gcaccaagca tcactaatga agctaacttc ttcatgttca tcgtaaaatc tccttttttt
    46381 gatgtgtgtt tctattttga caaccactat taggatttga gcgcttcgat aaaacgctct
    46441 gcaatttcct taggccttgt aatggcccct ccaacaacaa tacctgccac acctaagtca
    46501 ttaattttct tggcttcttc tggggaatga atctttcctt cggcaatgac agcaatgcct
    46561 gctttgcaaa gagcttctat caatgccaca tcaggacctg cttcctgacg gctatacggg
    46621 gtgtagcctg acaaggtggt tccaacaaaa tcaatgccag cctgatgggc cactagtcct
    46681 tcatcaaagg tactaatatc tgccatcaaa agctgattgg ggtacttttc cttaacttgt
    46741 cgaataaagc tagcaatatc caagccatca tgtcggtcac gcttggtaca atccatagca
    46801 atcactgcaa tatttaaggc agctaattga tccacttcgg ccatcgttgc cgtaataaaa
    46861 ggctcttgcg gcgggtaatc ttttttgatg ataccgataa ttggtaggtc tgttatggct
    46921 tgaatttctt taatgtctct aaccgaatta gctctgatgc cgacagcacc agcttcttga
    46981 gcagcttttg ccagcagtgg cataataccc ccagtctctg aatagagagg ctcacctggc
    47041 aaagcctgac aagaaacgat aatcccaccc tttaactgct ccatgagctt ttctttggtt
    47101 ggtttatcag gcatagtttc tactccttgt gtttcttagt tttaataaaa ataacgttca
    47161 caaagttatt ataacaaaaa ataaagcgct ttcaatagca atgagacttt tagaatctac
    47221 tttcattttt tatattattt tctattattt ggaatgctct ttcatacaac aaataaaaag
    47281 gtaaggagtt gacaccatac ttatacattg caaattcccg attagaaaac gttaaaaaac
    47341 caagagcctc gagcactctt ggtttacttt agttgtattt tttgcaatta agctgataat
    47401 actttacgtc ctttacgacg acgtgcagca agcacgcgac gtccgttttt agttgacata
    47461 cggtgacgga atccgtgttt acgttgacga cggattttac ttggttgata agtacgtttc
    47521 acagtgaata cctcctcata gattttgtat tcgtttagcc ggctatttgt gatatcagtt
    47581 actaaacata ctataatatt ctatcttaaa gagggtctac tgtcaagatt tattttcgtt
    47641 tttcaacagt ttctctctca tttaagaggc cgctcatttc ataaagtgtc tcttctttga
    47701 cactgttcct ttgccttacc gttgaaacct tatcaatagc aacaataatc aatgagatca
    47761 gtaaaacaaa cggttaagct ggccatacaa aaaatcttcg atagctaaac taactaccaa
    47821 agattctttt taggatctaa cgttgaagac tgactaccac atagcggtta gggtcattgc
    47881 cttcagaata actatcaacc ccttcaatgg atgaaacggt tttatgaacg attttacgct
    47941 cactgttact catgggatcc atggtgtaat cttgaccaga ttccaagacg cgtttggcaa
    48001 ctttttgcgt aaagtcaatc aaggtttctg ttcgatgttc cacataatca tggacattca
    48061 aggatactga aaaatttttt gaatagcggt cgtgcaagaa attttgagct aacaactgca
    48121 aggatttcaa aaccttacca tggtaaccaa tcacacgtcc cgcctctggc gtttcaatct
    48181 gcaaattgat ttggcgacga ttgttgctgg tttcaacggt ggcttcgata tccatttcat
    48241 agatgatttt agtcacataa tcggacactt cctgagcagc tttttcaata tctttgctga
    48301 aaccatcatt accaggatct tggggcactt ctgattcctc gactgggatt gacggttgtt
    48361 gtgcttttgt ttcagtgact gtctcagcaa gattagaaag ggtttgcgct ggactatctt
    48421 cagacatgag aggaaccact ttggtatctt ctgcttctaa cttttgagtg gcttttattt
    48481 cttcaggttc tacatcagca gaattgaccg cgggagcatt tttttgatta atatcctctg
    48541 gaacacctcg agtggctttt ttatcagcct tataaaccgt cttgtcgctg ataccttcga
    48601 tatcaacttg ggctggcttt ttaccgaacc cgaggaaacc ttttttctct tttgaaatga
    48661 ctttgatatg cgctttaagg cgtgataacc ctaactcttg aagtcctgtt tcgatagctt
    48721 cttcgactgt ttttcctgta aataatacca taacctaaac tcctattttc tcttcattgc
    48781 ttttttacga gcacgacgtt cacgaagacg gcgttctttt tcttcattgg caagacgctg
    48841 tctttcggca ataatcttaa aaggattgtt taatagcagt agttgtacca cttgaaaggc
    48901 gtttgagacc gtccaataga gcactactcc actagccaag ttaaagccca tgaaaaagat
    48961 cattagcggc atcacataaa tcataacagt catcatgaca tttttttctt tagccgctag
    49021 attggtcaac caagtggaca agaaagtgaa gacagctgcc aaaactggta aaaggtacaa
    49081 atgatcatgt tgtgccaatt ccacccacaa gaaagtccct gtttttaaga aagatacccg
    49141 tgtcaaggct tggaataggg caatcataac tggcatctga attaagaggg gtaagaggct
    49201 agcataaggg ttaaccccat attttttgta aagggcttga ctttcttcag ccaacttcat
    49261 ccgcgtttgt gtgtctttac cagcgtattt cttttgcaat tctctaagct caggttggat
    49321 gtcttgcatc ttctggcttg atttgatttg catattaaac aaaggcatga gcatgagacg
    49381 gatagtaagg gtaaaaagaa taatgccaac accaattgaa ccatcaaagg aaagccattg
    49441 aattgctctg gcaaataagt aaaccaactg gtcccaacca ctagatgatt gtgccgttac
    49501 ctcaccacga ccacaggcca ctaataatag aactaagggg actattcttg caattttaat
    49561 gtttttcttc actctcaaaa cctttctcaa gcaattgtgc taactttaaa acatgatgta
    49621 aattttgttg aagctcttga tactccaaag actcgacacc cttacgggca atcaccacga
    49681 aatcctctga cttcagctga tgccctaatg ccatgataac atgacgtatc tttcgtttga
    49741 ctgcatttct ggtgactgca tttcctattt ttttaccgac agaaataccc acacggaagt
    49801 ggtcttggcc tctatttaaa tgataaatga caaattttcg atttgctgta ctttttccat
    49861 ccttaaatat ggcttggaaa tctttctcac gcttgacacg ataggtcttc ttcaaaattt
    49921 aactccaata tctaaattat taccattata ccacatcccc taaaaaatta aaaagcccta
    49981 accctttcag attaagcctc tttctgtact atttctagtt tttgtgcttc aactgcctct
    50041 tgtcactcca tcttttcgta gtatagttct tctttcgaca aaggaataac cttcagaaaa
    50101 caaccataaa aagtcagaat ccacaagacg tcagctactt atccctgtat ttacctatca
    50161 aaaaacccgg caagccgggc tttgatactg attttacaat cagctaatgt gatatccaaa
    50221 caaagacaac tgacatcgtc attttgtctg ccgagccatc atatcaaaaa tactatttgt
    50281 ttatggagag agagaaaaca atattttgat tgaattgggg attgattgct cgataaactc
    50341 atgacttcgt aaatctttat ttacactaat tattatagcg aaaaatgttt caataagagc
    50401 atcatttcct gaaatgttgc tttttcgtcc taaaatgtta ttgctctctt aactttagcg
    50461 aagagcctcc caccgttcaa acagacattt catttttaat cgtgatacca tacaagaatc
    50521 accattttcg aaataaagga gctgcttact cttatcaatt cgaacaacct tatctagatt
    50581 cacaaggtag gatctatggc acaaaaaaag tttcggtgct actgcttgaa tctcagatag
    50641 attaccataa aactctaatc tttctgtctg agtccataaa caaactttgt gaggagttgt
    50701 ggctgtagca aagtataaaa tatccttata gggcaatttt aatcttgtct gtggagtctc
    50761 aaataaaaac atgtcctttg actcacgact agacatcata tcgtaagtat atcggataca
    50821 ttcttcgatt tgttctttaa actgtttttg accacctgct ttatcaataa aatctagagc
    50881 ggatacctta tatttaaaag aaataggagc aaattctgaa tgagtggtga caaacacaat
    50941 aacggcatta ggatcttttt gtcgaatagc tgcagctaat tcaagcccac aacgagtata
    51001 ttcaccaatt tcaatatcta aaaaatacag ctgatggtct cctctttctt ggatactctc
    51061 aaataatttt tgaggagtcg agaacacttc aagctgatta catggtattc tagtctcttt
    51121 taagatgcct actacgatag attctatgcg tgtctgctgg ataaaatcat cctcaagaat
    51181 aaaaatgttc atcatacttt atctcatttc taacaattgt cttaatcgat aatggtcact
    51241 tttagtcgaa agcgttattt gggggtaact atctaaaaca gtcaaaaagt gggctgagtt
    51301 ctgctgctga gcatcaaagc gtttggctat atccacacga ttggtttttg tgctattttc
    51361 aataataaat aattgcttgt tatcttgttt aaagtatgca atagataaaa aaggacgtct
    51421 actgcctttg gctgtctcaa tagcattgtc cactagtcca gtaaaaagta caattaagtc
    51481 gattaactta ataggtaaat gatcgataac atctggaatc tcaatataaa gttcaatacc
    51541 caaatactga gcttcaagca atttggaatt catgatactg cgaatcacag cctctttgat
    51601 attgtctaaa gaagatattt cataatttgt gcgcatcata gaagttgccg attgctgaat
    51661 aaccgtgtca taaactctag taatcagatc tatatcacca ctatcgatac tatcttttag
    51721 actaattaag atattttcag aatcatgttt aactgttctg atttctcggt aaagttgctc
    51781 aatcgattga ttgtaatttt ccagatacgc aatacgttca ttttgtgctt gtgttaattt
    51841 ttgtgacagc tgatctttag caaatcgatc taattttaca ataacccaaa taaaaatagc
    51901 taaataaata aatactaaaa tagaccggta ctggaaatat agtgcaagaa atccgctttg
    51961 cacagttacc aaaaaatggg cgaaaaagta gtaagaaaac atggcagtat tcatccaaaa
    52021 tacccacttt ttcatcttat cttcactgat aaaccttatt aagcttaagt caatactgaa
    52081 aatgtagcta aacagataaa atattggtaa tacaaaaaga taacataact ctaaaagctt
    52141 aaggttatta ttaatttgac caatgctaaa tcctaagaca gctggtaaaa agaaagatcc
    52201 gatgacgcga aacagtaatt cgacaatcaa gatagtaaag aaaccattaa acatatgctc
    52261 aaataatttc tttttcggag cacttaacaa actaacaata ataaaaaaca gttggtcaat
    52321 caaaatgact ttgtcaaata tcatattagc aattacaaaa ctaatgccta taacgctaac
    52381 ccgtttccag cttagtttaa tagcagaaac ctttgcaaaa atgacccagc tgttaataaa
    52441 gatggtagca tagaataaag ccatactgta tataaccatc atctatccac ctcctccttt
    52501 ggcatggtca aggtttggct aaattcctta tcaaaacttt tagtccgcaa ggataaataa
    52561 ggatactttt tgagaatacg ctgcgcatta gaaaggccga taccacgttc tgaacctttt
    52621 gaagaatagc cttcttcaaa gatcttgtta atgtctacct tttttttagt cgtatttgtc
    52681 acaacaaaca tctgatagtc atctaacaaa aagtaagcaa ttgacatatg aggttgctgt
    52741 gcttcaagag ctgcctcaat ggcgttatca caaaaaatag acatcaacaa tagtaagtcc
    52801 aactcaggaa tgtaagtctc ttttatatta tctggcactt ccacattcaa atcaatacct
    52861 gatttttccg cactgataat tttagctgac aataagctct taatcgatga gatattaatt
    52921 ttcctaagct tcgagatatt atagtgttta tcatcccagt agtcgttagc ttcatgaacc
    52981 gtttgggcat aaatatcttg aatctgagta atggattcac tcttaatggc ttgacctaaa
    53041 cgctctatac ggctcaggta atcactttga aaagctctta catctcgata gagtttctca
    53101 agatgtttcc cataagtctc taagttagtc atataagctt gttgttctct tctcaactca
    53161 tttttaaggt attctttaga actatgatta aaataagata gaagataaac taaaagaagt
    53221 ataaacatca aaaacaataa cttataaggt gtgggaacaa aaagagaatg atgaaaatgt
    53281 aaaaaggggt ccgtaaatcc taaaatgaca aaaatgtcca cataataaac caaaacaaaa
    53341 atcagcaatg tttgataaaa attatgcgat cgtttcgaat atccggattg gcatatcatc
    53401 ttgtaatctt ttccaatcat ataattaata atagcaaaac ttggaaaaat cagcagataa
    53461 gcaagcaagt caaagataat atgacccaga taaataccac tcgacaaaaa aagatagggg
    53521 ataacgattg tacccataaa ccgagatagc aaatccacca aaacactagg tgcaacagcc
    53581 aaaaaaagag ctttcaaaga aaataattgc ttggtttctt gccttaaaac aactaaaaat
    53641 aatagaggat caattagcaa tggcgacaaa tacgggaact gattgaaaaa tagggctaaa
    53701 gccaaaatcg ttagttgttt ccaaactggt aatgtgatat cagatagaaa ggaaaaaata
    53761 taaatttttg tcatataata gacaataatt gataataata aaaacatata ttcgctatta
    53821 gccatttttt tctcctttcc aactttatta ttttagcat
//
LOCUS       DATWEK010000010        46798 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.010, whole genome shotgun sequence.
ACCESSION   DATWEK010000010 DATWEK010000000
VERSION     DATWEK010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46798
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.010"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            79..333
                     /locus_tag="VCR92_000700"
     CDS             79..333
                     /locus_tag="VCR92_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEP4267787.1"
                     /translation="MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDA
                     FIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY"
     gene            354..749
                     /locus_tag="VCR92_000701"
     CDS             354..749
                     /locus_tag="VCR92_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEP4267788.1"
                     /translation="MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTIS
                     AGKNLVEKGSQTVENLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAFKE
                     WTEKDLLALKGIGPATVKKLVENGASFKK"
     gene            1035..1354
                     /locus_tag="VCR92_000702"
                     /pseudo
     CDS             1035..1354
                     /locus_tag="VCR92_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351072.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            1351..1914
                     /locus_tag="VCR92_000703"
     CDS             1351..1914
                     /locus_tag="VCR92_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEP4267789.1"
                     /translation="MNLIIIGAQASGKMTIEQEVARQTGMNLFHNHDSIDFVLRFMPW
                     SQESTALIERMRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVL
                     FVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHY
                     QKINNTHLTAAETAQLIIQKMTHIKEN"
     gene            1916..4564
                     /locus_tag="VCR92_000704"
     CDS             1916..4564
                     /locus_tag="VCR92_000704"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEP4267790.1"
                     /translation="MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPP
                     PNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGI
                     SRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFV
                     DLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATT
                     RPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKLIPIVGDEHADPEFGTGVVKITP
                     AHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVN
                     IEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDNRVDFYPPRFNDTF
                     LQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSA
                     LWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLI
                     HGLIRDEEGRKMSKSLGNGIDPMDIIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDAS
                     WNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVT
                     ENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKIV
                     RLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVERLKDLIRAVRNAR
                     AEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSI
                     ITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVIQKE
                     KDKQADYQAKYDATQERIAEMKKIKS"
     gene            4718..7126
                     /locus_tag="VCR92_000705"
     CDS             4718..7126
                     /locus_tag="VCR92_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HEP4267791.1"
                     /translation="MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFL
                     IGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFN
                     EMVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKK
                     LCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDT
                     VNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKR
                     DSKGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTG
                     DLGVLEHHSNVVKQANEDDDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANL
                     RRFSSLINSVVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEID
                     HRICYGGNLGELAEIVELTIEEKQIFSRTELRKFDDSDQKVHLTDVINLILGEENSVL
                     AIFNTKKTVHNCYTMLKDITDRPVYQLSTNMCAQHRLDLIAKIKTELQNNIPIICIST
                     QLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGKRDKGQVTLVNLTNEEENISRLT
                     EIKAKKEATESILHKIGSPIDISTLNRDFFEYYYANNQGLMDYPLEDNLSIYDYLSLN
                     IYQTANKKFKGKLKQAFKTAGAKMNLINNDMIGILVPYGEAEKKLAYLEELGMSHFLS
                     AEDYQTIKSLLKELQPFTVNVRENDPLFETTKSYLNGQILVLTSEYYDTERGVKYDSA
                     SFYF"
     gene            7259..7987
                     /gene="cas5c"
                     /locus_tag="VCR92_000706"
     CDS             7259..7987
                     /gene="cas5c"
                     /locus_tag="VCR92_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas5"
                     /protein_id="HEP4267792.1"
                     /translation="MYRSRDFYVRVSGQRALFTNPATKGGSERSSYSVPTRQALNGIV
                     DAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFV
                     WNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSY
                     YNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAF
                     KAPEEIKSVNDECMEYDAMEKGEN"
     gene            7987..9882
                     /gene="cas8c"
                     /locus_tag="VCR92_000707"
     CDS             7987..9882
                     /gene="cas8c"
                     /locus_tag="VCR92_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas8c/Csd1"
                     /protein_id="HEP4267793.1"
                     /translation="MDFFTSLLKTYEKAELADLVDHQKRSNEPVLLPIYHTSLKSNGK
                     NIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSHPAPHPLVDKFAYYSAEMG
                     QSQYDSFHKQLNNWIDYCEEGDVKRFLTIVQQFILKPEFLTLILDSLIGPDYQNNQLK
                     VTFCDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKTLHQSYISFVEANREKLGI
                     CNISGREEQLTDKHRGLMGNAKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLML
                     KYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEDDDDDTPPVITL
                     ATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLNKW
                     QETYSWESRSKFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLI
                     DGKPMPQSIVKKLGNNVKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRS
                     YLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEE
                     PLKLNRRGSWMKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNT
                     EVTESEE"
     gene            9887..10735
                     /gene="cas7c"
                     /locus_tag="VCR92_000708"
     CDS             9887..10735
                     /gene="cas7c"
                     /locus_tag="VCR92_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas7/Csd2"
                     /protein_id="HEP4267794.1"
                     /translation="MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSI
                     KRKIRNRLQDMGKSIFVQANERIEDDFRSLERRFSQHFTAKTPDKEIEEKANALWFDV
                     RAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTM
                     GTKHFVDYGVYVLKGSINAYFAEKTGFSQEDAEAIKEVLVSLFENDASSARPEGSMRV
                     CEVFWFTHSSKLGNVSSARVFDLLEYHQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTV
                     EILEGL"
     gene            10737..11411
                     /gene="cas4"
                     /locus_tag="VCR92_000709"
     CDS             10737..11411
                     /gene="cas4"
                     /locus_tag="VCR92_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HEP4267795.1"
                     /translation="MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQV
                     LHTKADNPYIKEKRKELLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWL
                     PKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSAL
                     RQEVKELAAEMQEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMT
                     SEEMDL"
     gene            11408..12433
                     /gene="cas1c"
                     /locus_tag="VCR92_000710"
     CDS             11408..12433
                     /gene="cas1c"
                     /locus_tag="VCR92_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated endonuclease Cas1"
                     /protein_id="HEP4267796.1"
                     /translation="MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGI
                     VCFSYLGVSPALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREE
                     SLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVNDELIWALEMVQAADNKDS
                     LRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQS
                     ALEAVGLDSYVGFFHTDRPGCASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVK
                     ENGSILMTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLE
                     SYPPFMV"
     gene            12444..12737
                     /gene="cas2"
                     /locus_tag="VCR92_000711"
     CDS             12444..12737
                     /gene="cas2"
                     /locus_tag="VCR92_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002280569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEP4267797.1"
                     /translation="MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVT
                     PAEFVDIKHRLTQIIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL"
     repeat_region   12885..13047
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=12886..12916
                     /rpt_unit_seq="gtctcacccttcatgggtgagtggattgaaa"
     gene            13208..13918
                     /gene="ccdA2"
                     /locus_tag="VCR92_000712"
     CDS             13208..13918
                     /gene="ccdA2"
                     /locus_tag="VCR92_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEP4267798.1"
                     /translation="MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTI
                     TIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGI
                     HQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVA
                     SGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHIFLLKKVGGVLIIV
                     MGILLMTGTLNNLAQLFG"
     gene            13931..14554
                     /locus_tag="VCR92_000713"
     CDS             13931..14554
                     /locus_tag="VCR92_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEP4267799.1"
                     /translation="MKKGLLVTTGLACLGLLTACSTQDNMVKKEITQDKMSMAVKKKD
                     KMSTSKDKSMMADKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASW
                     CSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFTKWFQGTDYKDLPVLLD
                     PDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH"
     gene            14597..15703
                     /gene="msrB"
                     /locus_tag="VCR92_000714"
     CDS             14597..15703
                     /gene="msrB"
                     /locus_tag="VCR92_000714"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEP4267800.1"
                     /translation="MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKK
                     VKSTKVDPNAPVDQKVIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIH
                     QTGHAETVEVTYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADL
                     AIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPV
                     IDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLF
                     SSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKD
                     QGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE"
     gene            complement(15814..16968)
                     /locus_tag="VCR92_000715"
     CDS             complement(15814..16968)
                     /locus_tag="VCR92_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEP4267801.1"
                     /translation="MPISYLKISTPQRKERGKTMIEKYTKKDGTTAYRLRAYLGVDPV
                     TGKQVRTTRQGFKTEREAKRAEVKLIDDFQRQGAWKSNDKTTFDDVAKLWFEQYQNTV
                     KPSTFLVNQNYYKTILKPHLGQLQMTKITVMICQKFVNCLSRYSGYTLYLSLANRIFK
                     FAVNLGIIDNNPMNKTLRSKCTYKNVDTLTKKYYTKEELNTFLRLVEAEETLEMRLIY
                     RLLSYGGFRIGELIALKDTDFDFRNNTISITKTIAYTKEGWAVQSPKTKKSNRTISMD
                     AETMSLAKLYIKQSIKPLHGSFKLFNFASDTVRKRLDRFILKHGLKRITPHGFRHTHA
                     SLLFEAGIPAKIAQERLGHAKIAITMDLYTHLSKKSKDNVADKLAELVAI"
     gene            complement(17087..17608)
                     /locus_tag="VCR92_000716"
     CDS             complement(17087..17608)
                     /locus_tag="VCR92_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267802.1"
                     /translation="MKKIVYLFTLSVLIVCLGACTGGSKKDTTSKTPSSDTSKVSGDM
                     SEKEYFDTLISKIDKVTTDNYKSDEYLFYDYKTILRDPKKYFSLKVRINNLKIIQISD
                     KDKYTKMLANTPNGDLYMLFIETKRLETKLLETDNITINGRYLLSYEYTTTSGSENSV
                     PLIYIDGYLLLDK"
     gene            complement(17619..17999)
                     /locus_tag="VCR92_000717"
     CDS             complement(17619..17999)
                     /locus_tag="VCR92_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEP4267803.1"
                     /translation="MMTPETVCQEKGIDLVYFDGRGTNIPGMFNKKHNVIAIDTYLDG
                     IYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLKEELSYWDNMEDFNYIQ
                     FMEKYELTSIADEVMVKEEFKNLI"
     gene            complement(18013..18372)
                     /locus_tag="VCR92_000718"
     CDS             complement(18013..18372)
                     /locus_tag="VCR92_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4267804.1"
                     /translation="MTMFEVYSRIEALAKKRGVSLQKVATDIGLSENYIYNLKSKKTA
                     NTDPIEKIANYFNVSTDYLLGRTDNPKMAQDGHTSVAIDLKKDAEETFFFDGHELNDE
                     DIDLITSILETRIKNRK"
     gene            19168..19359
                     /locus_tag="VCR92_000719"
     CDS             19168..19359
                     /locus_tag="VCR92_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267805.1"
                     /translation="MPDNAIAIEKIKKYLLDNNLKQVDLAVTYGKEPQDVANILAGRK
                     KDPASNRFVLKVISDLKIR"
     gene            19370..20098
                     /locus_tag="VCR92_000720"
     CDS             19370..20098
                     /locus_tag="VCR92_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEP4267806.1"
                     /translation="MNNLITVTLNENQEPIVSGRDLHQALEIKTQYTKWLERMSDYGF
                     EENEDYVAISQKRLTAQGNQTEYTDHVLKLDMAKEIAMLQRNEKSKQVRKYFIQIEKD
                     FNSPEKIMARALLMADKKVHKLEAQIEADRPKVLFADAVSASKSSCLIGELAKILKQN
                     GVNIGQNKLFQWLRANGYLISRRGESWNQPTQKSMQLGLFELKKTAINHSDGHTTTNV
                     TPKVTGKGQQYFINKFFNQEYLPV"
     gene            20131..20280
                     /locus_tag="VCR92_000721"
     CDS             20131..20280
                     /locus_tag="VCR92_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267807.1"
                     /translation="MPEDLIKQLEAGSEFLAKTCLHSKIIITVDGIRLVETKEFHPVS
                     GTLLD"
     gene            complement(20277..20477)
                     /locus_tag="VCR92_000722"
     CDS             complement(20277..20477)
                     /locus_tag="VCR92_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KTSC domain-containing protein"
                     /protein_id="HEP4267808.1"
                     /translation="MQRQYVSSSNARSVDWENNTLEVEFNNGSIYHYHNVSQTEYRSV
                     LVGSVGSNIHRLAKIHTYTRIV"
     gene            20466..20720
                     /locus_tag="VCR92_000723"
     CDS             20466..20720
                     /locus_tag="VCR92_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267809.1"
                     /translation="MTLHNFSSFRNDSFIIARRRNYTDRKENHMRPKRYPYSGKKNRK
                     AKDISLKLMSKEELSDFSRQIAEATRDSVEPFREPQSMMS"
     gene            20966..21223
                     /locus_tag="VCR92_000724"
     CDS             20966..21223
                     /locus_tag="VCR92_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267810.1"
                     /translation="MQSQLTYDLLKKQIAEELFDEFKKLIQEKDLANQWVNQTTLVNE
                     YGYSWQTIKRMESYGLKSFKNGKDKMYCLADVNEIKHLMKQ"
     gene            21252..21437
                     /locus_tag="VCR92_000725"
     CDS             21252..21437
                     /locus_tag="VCR92_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267811.1"
                     /translation="MNKLELFLLTTTIILAIIARIQYEVIKKHNSPENKRKIFREVAL
                     ENSKGWSEKRSRGEVVS"
     gene            21531..21788
                     /locus_tag="VCR92_000726"
     CDS             21531..21788
                     /locus_tag="VCR92_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEP4267812.1"
                     /translation="MLLTILRNKDEWRVYPEELARRHSDGLASVRAGLRELEKAGYVR
                     TYKKITRRSEGLQHYRFCSDCKISDEVFQRLVEQLKNELSD"
     gene            21910..22323
                     /locus_tag="VCR92_000727"
     CDS             21910..22323
                     /locus_tag="VCR92_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEP4267813.1"
                     /translation="MMKKKGEALDKKELFDNFQNNWMRLLSPFEIEDINKWIDEEKMP
                     VEVVNEALKSTILYNAPNLRYLNRVLNNWKRQGIDTVEKVEFARLQFENKKLSQNKNH
                     QSNVPSWSNPDYKEPDLKEFALGSIDGIEDGSGDF"
     gene            22304..22537
                     /locus_tag="VCR92_000728"
     CDS             22304..22537
                     /locus_tag="VCR92_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267814.1"
                     /translation="MDQEIFNFFNKQIKKDFGKTASKETFAKFASYCAEGIEKKGVKP
                     IFNWINLYAFGLGITTAEADRLRIERYKQENAL"
     gene            22534..22674
                     /locus_tag="VCR92_000729"
     CDS             22534..22674
                     /locus_tag="VCR92_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267815.1"
                     /translation="MTKQHRETLIWYRASHQERERLLDFGLVDKSQYVTLLRQLRKKY
                     AI"
     gene            22685..22939
                     /locus_tag="VCR92_000730"
     CDS             22685..22939
                     /locus_tag="VCR92_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267816.1"
                     /translation="MVEIRINGELVTFDSNFRDALIFTIDCLRGSEEPTLKQTYQTFK
                     DYTDEDLMDYIETEFDVWPELIVNRKIDSKWSTKQHILDD"
     gene            22961..23443
                     /locus_tag="VCR92_000731"
     CDS             22961..23443
                     /locus_tag="VCR92_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEP4267817.1"
                     /translation="MAYLYELEGIAAYLESLDLDDETFQNTLDSIDFQSDLENTIEYF
                     VKMLKNAQADVEMYKAEKEAFYKKQKQAEAKVEKYKETIRRAMELSQKKKVDAGMFKV
                     SLRKSKKVEILDETKIPLDYMQEKIEYKPMKSEISKALKSGIDISGVELIETESLQVK
                     "
     gene            23444..24118
                     /locus_tag="VCR92_000732"
     CDS             23444..24118
                     /locus_tag="VCR92_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HEP4267818.1"
                     /translation="MRKSESITEYAKAFCKAQLEVKQPLKDKDNPFFKSKYVPLENVT
                     EAITKAFANNGISFSQDPTTNAENGYIDVATLVMHTSGEWVEYGPLSVKPTKNDVQGA
                     GSAITYAKRYALSAIFGITSDQDDDGNEASKPNKTNQSQKPTNKTSKGASFQTPKISN
                     IQVETYKSDLSDIAKATNQNVEELTKWLTDTLKVKTLEDLRTEQIVSTDNLINKLKKK
                     AEQKND"
     gene            24111..24530
                     /gene="ssb"
                     /locus_tag="VCR92_000733"
     CDS             24111..24530
                     /gene="ssb"
                     /locus_tag="VCR92_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEP4267819.1"
                     /translation="MINNVVLVGRMTKDAELRYTASQVAVATFTLAVNRRFKEQNGER
                     EADFINCVIWRQSAENLANWAKKGALIGVTGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRNQQSGQGNSSQNDNSQPFGNSNPMDISDDDLPF"
     gene            24536..24739
                     /locus_tag="VCR92_000734"
     CDS             24536..24739
                     /locus_tag="VCR92_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267820.1"
                     /translation="MANRYRQRIYAVYDGDSFVDVGTKHELAERLGVTADTIVFIASP
                     AHKKRRPDGRHAEFIGYEDELEE"
     gene            24739..25179
                     /locus_tag="VCR92_000735"
     CDS             24739..25179
                     /locus_tag="VCR92_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HEP4267821.1"
                     /translation="MVKFTIPIEPKPQKRPRFSRWSGAYEDKDMMAWRKQVTDYVKNN
                     YEGPYFDDGLKVDVTFYLKAPELVSKKPSERARDKTKQKYQDYINELLYVPKKPDLDN
                     LEKAVYDSISKSEVVWTDDNIIVEHTTRKLYSPNPRIEVKINEL"
     gene            25176..25532
                     /locus_tag="VCR92_000736"
     CDS             25176..25532
                     /locus_tag="VCR92_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267822.1"
                     /translation="MTLVDDFYKRMKPSIKKFLDNNIIITDQEEAIRVYKSVKYYKKL
                     NRLPPPDVLEWFQQIYTTEEMVALIKQSYRLKQKKTDEDDKIYEKCMFKNYGDVKLAK
                     KVKRMNALAKAWEMGL"
     gene            25529..25780
                     /locus_tag="VCR92_000737"
     CDS             25529..25780
                     /locus_tag="VCR92_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267823.1"
                     /translation="MKRHRQFNKDIKYTPKSYNNLLPYDVVELLIARRDKTKVSDEVL
                     ADKIGIYAWNLEALLERRILPNESECKLIIDFLREVERC"
     gene            25774..26058
                     /locus_tag="VCR92_000738"
     CDS             25774..26058
                     /locus_tag="VCR92_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HEP4267824.1"
                     /translation="MLTEDTFKKIEELEAACQDTTDNIKKPSHYQGRHGMEAIDVVKN
                     FGACPEYEEGFYWGNAVKYLLRYHAKNGVEDLKKARQNLDWLIEKLEEVE"
     gene            26055..26324
                     /locus_tag="VCR92_000739"
     CDS             26055..26324
                     /locus_tag="VCR92_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267825.1"
                     /translation="MKKPNRYPYSKSKFNGCIYQLHSASFKDEQYVEDLKSCGIHYQI
                     TKIGYFPDIFIKIDNLEQLQILIDKTGHDLILSKDQIWIYDDYME"
     gene            26334..26738
                     /locus_tag="VCR92_000740"
     CDS             26334..26738
                     /locus_tag="VCR92_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267826.1"
                     /translation="MIPKFRAFNKKTKKMYSIDGFKASERKIYRCSLADDEFRSGCLE
                     TFHFVEDNLDDYILMQSTGLKDKNGVEIFEGDVVEYDDGEYLFAGKVVKTVFGTYVKS
                     YSFFSFEDFSDENTMTADVEIIGNIYEESVEE"
     gene            26735..26905
                     /locus_tag="VCR92_000741"
     CDS             26735..26905
                     /locus_tag="VCR92_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267827.1"
                     /translation="MRKYIEFKDEWKSAADHLNDFIDKNKYAKVTGDLWQGSDQVIAE
                     QCFLKVLEEMQK"
     gene            26902..27408
                     /locus_tag="VCR92_000742"
     CDS             26902..27408
                     /locus_tag="VCR92_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEP4267828.1"
                     /translation="MNIEEAKELVDNSKFYGKTSSVIKAEVRDIIDQLNQPKPEVPQC
                     VADWIEECKEEDLTLSLAYDVDAFGEVAKWLYDTNDSTNIDLFAQAWLAYPNITIEKE
                     KLYTVEIPDPNHDVGTVILSKNKHREAYIAIDYTGSWKERKANHLTESEIRKDFDWAW
                     QFAKEVTE"
     gene            27405..27575
                     /locus_tag="VCR92_000743"
     CDS             27405..27575
                     /locus_tag="VCR92_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267829.1"
                     /translation="MTEELGVLYSEKWHKYYLYKTCRYISYVDNPHQATKCTRKQAEQ
                     FPQFKWVPLTKL"
     gene            27849..28289
                     /locus_tag="VCR92_000744"
     CDS             27849..28289
                     /locus_tag="VCR92_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEP4267830.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLREYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVPSKPVERLALNRVSAEQELDAIERAVNGIFDPEYRLILIDKYLLTYPKTD
                     CDIYTKLGYEKSQYYNMLDNALLSFSELYKEGMLLVEKLEKSWN"
     gene            complement(28928..29185)
                     /locus_tag="VCR92_000745"
     CDS             complement(28928..29185)
                     /locus_tag="VCR92_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267831.1"
                     /translation="MLSLLPTPFWDTSIYRTGTVGIEPTHLLLALRKEFSDLAIVPKQ
                     GATLTVFQSRFMFQRFRRAKTSHKRSSTDLARIERATALNI"
     gene            29266..29784
                     /locus_tag="VCR92_000746"
     CDS             29266..29784
                     /locus_tag="VCR92_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEP4267832.1"
                     /translation="MGFVDKKLSEITPYKNNPRNNDEAVGPVAESIKEFGFKVPIVVD
                     KNGEIINGHTRYKAAQKLGLETVPVIVADDLSEEQIKAFRLADNKVGEIAVWDLDLLN
                     EELNDILDLDMSAFGFELEIDDENQENLDADFEEIEDDSVLIVEAESEEELEKLYDEF
                     VERGFKCRVSIL"
     gene            29763..30440
                     /locus_tag="VCR92_000747"
     CDS             29763..30440
                     /locus_tag="VCR92_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267833.1"
                     /translation="MPSFNIVKKNDLNSSFKVSKVMADFDVGAEHVREHFIGKIDYPD
                     KWQIGLIVGGSGTGKSTIAKELYNEALEDDFVYPDKPVIDCIPCHNVEELQKMFYAVG
                     FGSVPSWLKPYHVLSNGEKMRVDLARRILTKEFIVFDEFTSVVDRQVAKIICIALKKA
                     LKRYPDKKFIAVGCHHDVIEFLQPDWCFNTDDMQQVFRFPHEANKNSQSEDAQLPSGE
                     NLDVIII"
     gene            30356..30832
                     /locus_tag="VCR92_000748"
     CDS             30356..30832
                     /locus_tag="VCR92_000748"
                     /inference="COORDINATES: protein motif:HMM:NF012792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP4267834.1"
                     /translation="MPPRSKQEFTVRRCSIAEWGKFRRYHYLNGDIVRAARCFGLYDD
                     DKIIGFIGVIHFPHPKNKKIKRVTRLVILPDYQGVGLGTRFLKSVAEIYSCQGFDFRI
                     VTSAKNLINALNRNTNWKLKSYDKGNTPTGNSSIKQLAKTTRKNVKIASFLFIRKN"
     gene            30893..31270
                     /locus_tag="VCR92_000749"
     CDS             30893..31270
                     /locus_tag="VCR92_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEP4267835.1"
                     /translation="MNKIEAIISIKPQFVDEIMKGNKRFEFRKSFLKSIPDRCYIYST
                     KPVGKIVGFFTIKQVLRDEPEKIWQKTSKKSGITKDFFDEYYSGKNKAVAIEIDRLFA
                     YKTPKNYHEIDIKGKPPQTYKTI"
     gene            31321..31794
                     /locus_tag="VCR92_000750"
     CDS             31321..31794
                     /locus_tag="VCR92_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267836.1"
                     /translation="MANEENLIPGNKRSKSELREITRKGGIASGKARRRKKELKTIIE
                     QALNSVIPNEKAQKKLESLGFDPTFQSAIALKVVEQAMNGNLRAVELISNISFAGKDS
                     LDRKEQRQRIKAAELTTDEQRTRIELLKVKLDAEKGAKPDTSLMKALLDAVEGGD"
     gene            31877..33088
                     /locus_tag="VCR92_000751"
     CDS             31877..33088
                     /locus_tag="VCR92_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEP4267837.1"
                     /translation="MTPRSGKTTAGHFRYARYLIESEDENHLVTAYNQEQAYRLFIDG
                     DGTGLMHIFDGNCEIKHDERGDHLLITTPKGNKRVYYKGGGKVNSVGAITGMSLGSVV
                     FCEINLLHMDFIQECFRRTWAAKLRYHLADLNPPAPQHPVIKDVFDVQNTRWTHWTMD
                     DNPILTAERKQNIINSLKKNPYLYKRDVLGQRVMPQGVIYGLFDTEKNVLDALIGEPV
                     EMYFCADGGQSDATSMSCNIVTRVRDNGRISFRLNRVAHYYHSGADTGQVKAMSTYAL
                     ELKVFIDWCVKKYQMRYTEVFVDPACKSLREELHKLGVFTLGAPNNSKDVSSKAKGIE
                     VGIERGQNIISDGAFYLVNHSEEEYDHYHFLKEIGLYSRDDNGKPIDKDNHAMDEFRY
                     SVNVFVHRYYN"
     gene            33102..34604
                     /locus_tag="VCR92_000752"
     CDS             33102..34604
                     /locus_tag="VCR92_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEP4267838.1"
                     /translation="MGVIQKIKNLVTRSKYVMTTQSLTNITDHPKIAISKLEYDRITT
                     NLKYYKSDWDSVLYLNTDGETKKRDLNHLPIARTAAKKIASLVFNEQAEIKVDDDAAN
                     EFISETLKNDRFNKNFERYLESCLALGGLAMRPYVDGDKVRVAFVQAPVFLPLQSNTQ
                     DVSSAAVVIKSVKTINGKEVYYTLIEFHEWQSSDDYVISNELYRSDDKAKVGSRVPLS
                     EVYKDLKDEAKVTDVTRPIFTYLKTPGMNNKDINSPLGLSIFDNAKTTIDFINTTYDE
                     FMWEVKMGQRRVAVPESLTALTVRTTDGDVVPRPRFESDQNVYIRMGGRDLDSSAIQD
                     LTTPIRADDYIKAINEGLSLFEMQIGVSAGLFSFDGKSMKTATEIVSENSDTYQMRNS
                     IVALVEQSLKELVISIFEIAKAYDLYQSEVPSMDNISISLDDGVFTDRDAELDYWIKV
                     VNAGFGTREMAIQKVLNVTEEKAQEIAAEINTGIVDEINQQRTDTHLYGE"
     gene            34609..36087
                     /locus_tag="VCR92_000753"
     CDS             34609..36087
                     /locus_tag="VCR92_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor capsid protein"
                     /protein_id="HEP4267839.1"
                     /translation="MKKKPIKLNDEQLLLEASQLSDMYHQLTLDLFDQVIERIKARGS
                     ASLADNPYLWQANKLHDVGLLNADNIKLIAKYSGIAEAQLRYIIKNEGFKIYKNTSEQ
                     LEEALGRESGVNSTIQDDLSNYARQAIDDVHNLTNTTLPFSVIGAYQGIIQDAVAGVV
                     TGLKTPDQAINQTVIKWFKKGFYGFTDKAGRKWRADSYARTVINTTTWRVFNEVKEAP
                     AREFGIDTFYYSKKATAREMCAPLQHQIVTTGEAREEGGIKILALSDYGHGEPDGCLG
                     INCKHTKTPFVVGVNSKPELPEHLKNITPAQAKANANAQAKQRAIERSIRKSKELLHV
                     AKQLGDKELIRQYQSDVRSKQDALNHLVNSNDFLIESKSRSKMFVTDLMKREIVMKKG
                     LINDIIGLQTSDGITIKEISGHLLERIYERGVSESHIATALANPIYIRPDAVDGGRKV
                     SRRYVGTHVTVNINPHTGKIITTWKTGERTRRKYDNQRNVDK"
     gene            36059..36298
                     /locus_tag="VCR92_000754"
     CDS             36059..36298
                     /locus_tag="VCR92_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267840.1"
                     /translation="MTIREMLISNQILNNDDIDFMLSVNQDVSPLFELEDNDDNWDVL
                     VDELQQTSSYLTGDGESVSDRTKKFDDLVDKISAI"
     gene            36360..36626
                     /locus_tag="VCR92_000755"
     CDS             36360..36626
                     /locus_tag="VCR92_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267841.1"
                     /translation="MNKRIKKKRKLETAVVLLIAENARQAEAIKNQNKQIMELKSIVQ
                     RNALATNEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRKWGK"
     gene            36752..37366
                     /locus_tag="VCR92_000756"
     CDS             36752..37366
                     /locus_tag="VCR92_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267842.1"
                     /translation="MHMENVTNENVDQETTDLENNQQEDKAFTQDDLNRVGTKEHSKG
                     YNKAVKDLGFDDVESAKDALKAFKEWKESQKSESEKQTEILNAKDKELEEARANNKAL
                     NAKLAAMSLGVNAESIDDVIALSERLVTDETSIEDAIKTVLGKYPHFGQTKDKAPKIT
                     VAGNPSADNGQGSVSKEDFAKMSYQEKLDLKLKNKNLYDQLKGN"
     gene            37370..38188
                     /locus_tag="VCR92_000757"
     CDS             37370..38188
                     /locus_tag="VCR92_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HEP4267843.1"
                     /translation="MAVGTTKMAQMLDPEVLADMIDAEVGKAIRFAPLAEVDTTLEGQ
                     PGTTLTVPKWDYIGDAEDVAEGEAIPMTQLGFKKTTMTIKKAGKGVEITDEAILSGYG
                     DPVGQAAKQIVEAIDHKVDADVLDALSKSTQTVEATATVDGVSKALDIFNDEDDAETV
                     IVMNPADASTLRLDAAKEWLGATEVGANRVVSGVYGEVLGVQIVRSRKCPKGTAYMVR
                     KGALRIMLKRNTMVETDRDITKAINQIVANKHYGVYLYKAEKAVKITLKDAAKK"
     gene            38242..38658
                     /locus_tag="VCR92_000758"
     CDS             38242..38658
                     /locus_tag="VCR92_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267844.1"
                     /translation="MEVVIIAFLTQKEFEDLGFDDVEDFEKMEKRASHAVNLYCRNRY
                     DYKDLKKEIALVQKAVKRAIAYQIAYLNDSGVMTAEDKQSFAGISLGRTSISYTVGHG
                     QGSQQKTLADRFNLCLDAENELLVVGLGYTGISYDR"
     gene            38648..38980
                     /locus_tag="VCR92_000759"
     CDS             38648..38980
                     /locus_tag="VCR92_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEP4267845.1"
                     /translation="MIDKRLLIDELQVKLVKDKGDYGGFVYDEPFTLSPVRFDRNLAT
                     AGKDNARQETKPSVIFIYPKYCKTVADRSWVDAVVIDGDTEYTVDKVIPVYHPLTNKI
                     FCFEVEVI"
     gene            38980..39336
                     /locus_tag="VCR92_000760"
     CDS             38980..39336
                     /locus_tag="VCR92_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEP4267846.1"
                     /translation="MAKVVVELGGIKRKVSPQALAKGKLIMNNQVMMSMNPYVPYRDG
                     ALRGSSRANSVGVTWSGPHARAQFYGGAYNKYKSFKFKKYTTPGTGKRWDKRALANAT
                     IVKDWEKSLLRGMGFK"
     gene            39333..39731
                     /locus_tag="VCR92_000761"
     CDS             39333..39731
                     /locus_tag="VCR92_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEP4267847.1"
                     /translation="MTNDFATVLRQFVEGLDLGIKPRLDYLTRQEDLAIYPMPGGKVN
                     NEYMDGTREISLPFEIAIKTKNQELASTVMWTINSALSNFDLKLPSLNHSYTFISLDV
                     EKPFLNDLSDQGFYIYVLDITAHLEIEGNN"
     gene            39731..40216
                     /locus_tag="VCR92_000762"
     CDS             39731..40216
                     /locus_tag="VCR92_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEP4267848.1"
                     /translation="MRQKNALRGHFIAPYVKGEEKTEVTKEKLLELARWIKDISDDTD
                     EKTEDEAYYDGDGTEETTVVGVKGAYTFEGTYDPEDKAQAHIASLKYKLGDERKVWHL
                     IVSADGKTQWLGVATVTEIIAGSGAAADFEAFGCKITYNSLPKESKEIIPKKNELSVA
                     M"
     gene            40255..40689
                     /locus_tag="VCR92_000763"
     CDS             40255..40689
                     /locus_tag="VCR92_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267849.1"
                     /translation="MSGIVVDLKRTGFPVKIGQVELWFDTSQERLIEFFDIETEVNRR
                     LNEYEKQVIEANLDNEIEGKGVTKDVAQSALDLEAKYLEINYDLLFGEGTFAQLYAEY
                     PDKEALENTLEIVCREIEVKLKELAIEREKIVKQKTKKYKKE"
     gene            40693..41274
                     /locus_tag="VCR92_000764"
     CDS             40693..41274
                     /locus_tag="VCR92_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage Gp15 family protein"
                     /protein_id="HEP4267850.1"
                     /translation="MKLNDPLVESFEFRGEIYPIDLSFNKVLDVFDVIDDDFLNEAEK
                     CFLCLDILLDRTDLPFTYAVDLWVYIKTNFIDAERPEKPQLDIKGNPMPVVKEKEDNK
                     KVIDLSLDAEFIYASFRQTYQINLLKEQNRLSWIEFKALLNALPDDTVMQRIIAIRQW
                     EDDGEGSKKYRDNMRKLKAKYSLDDGEEEDDGS"
     gene            41264..44524
                     /locus_tag="VCR92_000765"
     CDS             41264..44524
                     /locus_tag="VCR92_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015967413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEP4267851.1"
                     /translation="MAADGKVTILVDVDGKQVKVLNSELDKVAKHGDKGSSSLKKFAV
                     GAGVFKLASAAVDLVSQSLGKAITRFDTLEKYPRVMKAMGHSAEDVARSTDKLANGID
                     GLPTTLDEVVGTAQRLTSITKDINKSTNLTLALNNAFLASGASSEAASRGLEQYAQML
                     SAGKVDMQAWKTLQETMPYALQQTAEAFGFAGASAQKDFYEALKNGQITFDQFSNKLI
                     ELNDGVGGFAELAKENSKGIETSFNNIKNAIAKGVANSIKALDDLSKAATGKGIADHF
                     DSLKVVINASFSAINASIKASTPLFKLLFSVIGAGISVVKALSPALVGVASGLAAMRA
                     VNETITMIKALNRAWVMASASMSIGATTIKTVTAVQAVSTTMTKADMVARLSQLGVLK
                     ASTVIYGVMTGAISLSTAATIAGTAAVTALKAALVALTGPVGWVVGAIGALVAVGVSL
                     WSWLTKESDETKKLKKEQEGLVESNKQLRDSVREGVQERKKGLESVKESTAAHQKLAD
                     EIIKLAAKENKTAGEKRNLKNKIDELNGSIDGLNLAYDKNSNSLSHNADQIKSRISAM
                     EAESTWQTAQQNLLNIEQKRSEVSKKLAENAELRKKWNEEANVSDSVRKEKIAELTEE
                     EAKLKNMQTQLQEEYNKTSATQQAAADAMAAAEESGSARQVIAYENMSEAQRTAIDNM
                     RTKYSELLETTTSIFDAIEQKTALSVDQMNANLEKNRAATEQWATNLEILAQRGVDQG
                     ILEQLRRMGPEGATQTQVFVDATDAELAPLQENFRAATETAKNAMGSVLDSAGVEMPE
                     KVKGMVTNVSTGLQAELQAANFAQLGQEIPNGVSQGISQGAGKASDASVKMGQEVKRS
                     FQGELGIHSPSRVFTEYGGHITDGLSNGVTNGTSKVMQTMQSLAQQMSQKGQQIVNDM
                     RSKSNQITDAFSTMSGPMHSHGVNAMQGLANGIYAGSGAALAAAQSIAARITATIQSA
                     LDIHSPSRVMRDEVGRFIPQGIAVGIDADRKVIDSSMQKLKESMTINATPEIASGFGG
                     GVAGIANQTTNNSNNSFTLNVKVDESDGNSREKYQRLFREFSWYIQQQQGRLGDVK"
     gene            44521..45237
                     /locus_tag="VCR92_000766"
     CDS             44521..45237
                     /locus_tag="VCR92_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEP4267852.1"
                     /translation="MTAFIKFDGKKSSDFDLRIINDVEHDSSFYDVDQVKVPGRDGVV
                     LKDNKRLEAIERSYPLRLYSKRRLTEVETDISNWLNVKGWKDLELSWEPDYIYKATHI
                     TPFSIKEVLRNFGRLKINFLIHPIKYLKTGKQEVPLVNGGTLQNPGNVQAKPILKIKG
                     TGNGVLTINDFETGLENVQGELVIDMERHLVYKDVLSAWDNIVRTERHRMPLFDVGQN
                     KISWTGSFTITAVPNWGVKV"
     gene            45234..>46798
                     /locus_tag="VCR92_000767"
     CDS             45234..>46798
                     /locus_tag="VCR92_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEP4267853.1"
                     /translation="MIPVLYEAKETKFRTFGLGEIADAYEVKATRERNGNYSLYIKYP
                     LDGVFASVFKEEMKIKSDAGRRTKWQTFEINRVLRNSKDHIEIFARHISMRTQDIALK
                     PFVNGASVGAESALEIWKKNLVGDDKFDVKSDILTLGSFNWEIDKIGNARDALGGVAG
                     SILDVYGGEYEFDNRTIILRKQMGRKAPTVLEYGRNIVSVEEERLLDGNYTSIYPYVR
                     YTPQPKPQEETPGKPHVGEHKQPEEQLVTLPEFILDGQYLSLYAQRRIQMVDLSSHFN
                     DDKNKKEPTIEEIRKLAQKYLKDNNVGAPKVSIEVDYIDLSQTLDYQDFRVMEEVELC
                     DIVPLYYPKFGITTESEKVVEIVYDVYTDSNHTIKLGTIGQSISKSLTGGVFERINAL
                     ENNQKVITNNQKQFELNLPKYLNDINGKRVWYEKPDDNIEHKIGDYWFEKNGKYQRTW
                     IWDGHQWVKVLDTEDLNPNQRAFDEAMAEIEKVKKAQEEINQRTDKELEEFRATLKNL
                     ALPEEAIKKITEA"
BASE COUNT        15594 a         8073 c        10110 g        13021 t
ORIGIN      
        1 cagttattaa taacatggca caagaggcct gccttatggt ataatggtaa agatgatttc
       61 agaaagagga agctaagcat gtcttatgaa aaagaatttt taaaagattt tgaagactgg
      121 gttaaaactc agattcaagt caatcagcta gccatggcaa ccagtcaaga agttgcccaa
      181 gaagatggcg atgaaagggc taaagatgcc tttattcgtt atgaaagtaa gttagacgcc
      241 tacgaatttt tactaggtaa atttgacaat tataaaaatg gtaaagcctt tcacgatatt
      301 ccagatgagt tatttggagc aaggcattat taaggacaag gagacacgaa atagtggcaa
      361 aacaaaaaaa tcgtaaaaaa gcattgaagt tagaaatgaa gcgtaatggc ttgttaaaaa
      421 aagcaggtca agtttttgat aaggcagttg aaagtgttga aacagccgtg gataaaacca
      481 tttctgctgg taaaaatctt gtggaaaaag gcagccaaac ggttgaaaac ctgacagcaa
      541 gcaaggaaag acttactctt gatgagtttg cagggcagcc agttgtagct ggtatccgct
      601 ctgaccttgt cgaaacccta tatgcagaag gcatccattc agcgcaagct tttaaggagt
      661 ggacagaaaa agacctcctt gctcttaagg gcattggccc agcaacggtt aaaaaattgg
      721 tcgaaaatgg cgcaagcttt aaaaaatagt catcttctcg ttgcttaatg gctataaatt
      781 tgttagaata ttagcaatca gaggtgcatt gagttggtct gttacagaga gcggtggtgt
      841 tgagaaatcc gcacagatgt caaggctggt agctgaggat aagaaatcag atatgaaaag
      901 tagcagatcc attttatggt ctgaaacagt ggtggtaccg cggaaatcgt aacacgaaat
      961 tcgtccctgt ccagtgtaag ctggataggg attatttggt ttcatttgaa agaagatgat
     1021 ggcttattgt taaaatgttg ttagaagtat acaatagaaa aactttgccc aaagtggaaa
     1081 cagaacggct gctattacgt caacgaaaag gggacaaggc attattccag aagcggcttc
     1141 agctctgatt gaaattggtt ttaccttact tgatttgcat aaaattgagc tgggttgcta
     1201 cgactacaac aagcaaagtc aggcagtggc tcgcaaatta ggctttacct tagaagccaa
     1261 tgtccgtgag cgtaaggacg ttcaaggtcg ccgctgtggc ggcatgcgtt ttgggttact
     1321 gagaagtgag tgggaggagc agaaacaaaa atgaacctta tcatcattgg tgctcaagcg
     1381 tcgggcaaga tgaccattga gcaagaagtt gccaggcaga caggcatgaa tttgtttcat
     1441 aatcacgatt ctattgattt tgttttacgg tttatgcctt ggtctcaaga gagcactgcc
     1501 ttgattgaac gtatgcgttt tgcttttttt gaaacctttg ctaagacagg tcaagacatg
     1561 atttttacta ttgtaattga cttcaatgat ccaaatgatg tagcaatgct tgaaaagatt
     1621 caggctgttt ttcagtctta tgaccaagag gttctctttg tcgaattaaa aacagatata
     1681 gaggaacgtc ttaaacgcaa tcgcacagaa aatcgtctca aacataaacc tcttaaacgc
     1741 aacatcgagt ggtcagaaca agatattcaa tccacgatgg catatgctgt ttttaatcca
     1801 gaagaaccac ccaaaacgct cacgcattac caaaaaatca ataataccca tctcaccgct
     1861 gctgaaacag cgcagcttat tatccaaaaa atgactcata tcaaggagaa ctaagatgac
     1921 agaactatca cctaaataca atcctgccga ggttgaggca ggtcgctatc aaaaatggct
     1981 tgatgcagat gtttttaagc catcaggaga ccaaaaagca aaaccgtatt ctatcgtgat
     2041 tccaccgcca aatgtgactg gtaagttgca cttaggacac gcctgggata cgacgcttca
     2101 agatattatc attcgtcaaa aacgcatgca gggctttgat acgctttggc ttccagggat
     2161 ggaccatgca ggaattgcga cacaggctaa ggtagaggag cgtctgcgcg agcaggggat
     2221 ttctcgttac gaccttggtc gtgacaaatt cctagacaag gtctgggagt ggaaagacga
     2281 atatgccact acgattaaag agcagtgggg caaaatgggg ctttctgtgg actacagccg
     2341 tgagcgcttc acccttgatg agggcttgtc aaaagcagtt cgcaaggttt ttgttgacct
     2401 ctacaaaaaa ggctggattt accgtggtga attcatcatc aactgggatc ctgctgccag
     2461 aactgccctt tctgacatcg aggttatcca caaggatgtt gagggagctt tctatcacat
     2521 gaactatatg ttggaagatg gctcacgcgc ccttcaagtg gcaacaacgc gaccagaaac
     2581 catgtttgga gacgttgccg ttgccgtaaa cccagaagat cctcgttaca aagatttgat
     2641 tggcaaaaat gttattttac caatcgtgaa taaattgatt ccaatcgtgg gtgacgagca
     2701 tgctgaccct gaatttggga ctggagttgt gaaaatcacg cctgcccatg atcctaacga
     2761 tttcgaggtt ggtcaacgcc ataatctacc acaagtgaat gtcatgaacg atgacggtac
     2821 catgaatgag ttagctggcg actttgcagg catggaccgt tttgaagctc gtcaagctac
     2881 cgttgctaaa cttgaagaac ttggtgccct agtaaacatc gaaaaacgtg ttcactcagt
     2941 aggtcactca gaacgttctg gtgcagtcgt tgagcctcgt ctatccaccc aatggtttgt
     3001 aaaaatggat gagcttgcta aacaagctat ggacaaccaa gaaacagata accgagtaga
     3061 tttctaccca ccacgcttta atgatacctt ccttcaatgg atggaaaatg tccatgactg
     3121 ggtaatctcg cgtcagcttt ggtgggggca ccaaattcct gcttggtaca atgcagaagg
     3181 tgagatttac gttggcgaag aagcaccaga aggtgatggc tggactcaag atgaagatgt
     3241 tcttgacact tggttctcat ctgctttatg gccgttctca actatggggt ggcctgacac
     3301 agatgtagaa gatttcaaac gttatttccc aacctcaacc ttagtaacag gttatgacat
     3361 cattttcttc tgggtgtcac gtatgatttt ccaatcgctt gaatttaccg ggcgtcagcc
     3421 attccaaaat gtcctgattc acggtcttat tcgtgacgaa gaaggacgca aaatgtctaa
     3481 atcattgggg aacgggattg atccgatgga tatcattgag aaatatggtg ccgatagctt
     3541 acgttggttc ctctcaaacg gctctgcccc aggacaagac gtgcgtttct catacgaaaa
     3601 aatggacgcc tcttggaatt tcattaataa aatttggaat atttctcgct atatcctcat
     3661 gaataatgaa gggttgacct tggaagaagc tgaaagtaat gtggctaagg tagctgcctc
     3721 agaagctgga aatgtgactg accaatggat tctccacaat ctcaatgaaa ccatcgctaa
     3781 agtgacagaa aactttgaca agtttgagtt tggtgtggca ggacacattc tttacaactt
     3841 catctgggaa gaatttgcca actggtatgt ggaattgacc aaggaagtgc tatatagcga
     3901 caacgaagct gaaaaagtta tcacgcgctc tgtccttctt tatactttgg acaagattgt
     3961 acgtctcctt cacccaatca tgccatttgt aacagaagaa atttacgctc aatatgccca
     4021 aggttctatt gtgacggtgg actatcctgt ggttcgccca gcttttgaaa atgaagctgc
     4081 gcataaaggt gtggaaaggt tgaaagacct gattcgtgca gttcgtaatg cgcgcgctga
     4141 agttaacgtg gcaccatcaa aaccaatcac cattttggtg aagacagcag atagtgagtt
     4201 ggaagacttc ttcaccagca acgtgaacta catcaaacgt ttcaccaatc ctgaaaaatt
     4261 agaaatcagc tcagccattg ctgcgccaga gctggctatg accagtatca tcacaggtgc
     4321 tgaaatctac ttgccactag cagatttgct taacgtggaa gaagaactcg ctcgcctaga
     4381 taaagaactg gctaaatggc aaaaagaatt ggacatggtc ggcaaaaaac tcggaaacga
     4441 acgctttgta gccaacgcca aaccagaagt catccaaaaa gaaaaagaca aacaagccga
     4501 ctaccaagcc aaatacgacg caacccaaga acggattgca gagatgaaga aaattaaatc
     4561 atagtgttta gaacgcagtt gaaaaactgt gttcttttct tactaataga gatattagat
     4621 tgaagtttaa ttatgagaaa aacgctttct ttatttaaag agttatgtta caatactatt
     4681 acaatcatcg tacaaatagt gttattttga ggggcatatg agaatgattt tagcacacta
     4741 tgactgtaaa aaagataaaa agcaatcttt agatgagcat ttatggcatg tggcctgttc
     4801 tagtcgacag gaagcatcta taattggtca aggagatgtg ctttttttaa ttggtcttta
     4861 ccacgacctg ggcaaagctg atcgaacctt tcaagataaa ttattaaata atccaaatcg
     4921 gcatgttgat cactcttatg caggggcaaa atacttatgt tctattattg ggcctcatct
     4981 aaaaaaccga ggggttgata aaaatgagag aatgacattc aacgaaatgg tggggtatgt
     5041 catctctgct catcatggga tgtatgattt atgctactat tttgacgatg ctgaatatta
     5101 tggctttaat aagtttaaaa atcgtatcaa tagagactta gatggttatc actatcatga
     5161 agatattaaa gggtacgctc taaaattaga aaaaaaatta tgtgattatg gctacaaaga
     5221 tttaagggag cttattgata aagcttttga taattaccaa caagccatgt cttccttaaa
     5281 ctggcaagat aagagtgagt gggattatta tcagtcttgt atggtgagac tttacttgtc
     5341 actcttaaaa aacgctgata ttttggacac agtaaatgcc tatggcctta agataagtcc
     5401 tatggataaa acagagcgat cctttctaaa acactcctat ttagcggcca ttgaacaaaa
     5461 atatgctagc tttggacagc caaacaatca gttgaacact attcggacag aaatcgctga
     5521 gcgtgttaaa gaaagaggta aacgagattc caaggggatt tatcgcttag atttaccgac
     5581 aggagctggc aagactaatc ttagtatgcg ttatgcgttt caccaattag ttcatcacga
     5641 caaatcaagg tttttttaca taacgccctt tctttcggtt cttgaacaaa atgcttccga
     5701 aattagaaaa gttacaggtg accttggcgt cctagaacac cattccaatg tggtgaaaca
     5761 ggctaatgaa gatgatgatg acaaggacag tttattgtca gcttatctta gtgatagctg
     5821 ggacagtcaa gtagtcttga cttctatggt tcaatttttc caaacacttt tcaaaacaaa
     5881 atcagctaat ctgagacgtt tttcaagttt gattaatagt gttgtgattc tagatgaagt
     5941 tcaatccctg cctattgaag tcaccacttt gtttaattta acgatgaatt ttttaaataa
     6001 agttatggat acaaccatcg ttctttgcac agcaacacaa cctgcttatg attcttcaga
     6061 gattgaccat cgtatctgtt atggagggaa cttgggagaa ttagctgaaa tcgttgagtt
     6121 aacgattgaa gaaaaacaga ttttttcaag gacagagctt agaaaatttg atgatagtga
     6181 tcagaaagtt cacttgactg atgttattaa tcttattcta ggtgaggaaa actcagttct
     6241 tgctattttt aatacgaaaa aaacggttca taactgctat actatgctaa aagacattac
     6301 tgatagaccg gtctatcagc tttcgacaaa tatgtgtgcg cagcatagac ttgacttgat
     6361 tgctaagatc aaaacggagt tacaaaataa tatccctatt atttgtatta gcacgcaatt
     6421 aattgaagca ggtgtagatg ttgattttca tcgcgtcatt cgttcctact cagggattga
     6481 ttctattgtt caggctgctg gacggtgtaa ccgagaaggc aaacgagata aagggcaagt
     6541 cactcttgtc aatctgacca atgaagagga aaatatttct aggctgacag aaataaaagc
     6601 taaaaaagaa gccacagaat ctattcttca taagattggg tctccaattg atatctcaac
     6661 tttaaaccgt gacttttttg agtattatta tgccaataat cagggactga tggattatcc
     6721 tttggaagac aacctatcaa tctacgacta tttaagcctt aatatttatc agacggcaaa
     6781 taaaaagttc aaaggtaagt taaaacaagc ttttaaaaca gcaggagcca aaatgaacct
     6841 catcaataat gatatgatag gaattctcgt accttatggc gaagctgaga aaaaattggc
     6901 ttatttagaa gaattgggta tgtctcactt tttatcagca gaagattatc aaacgataaa
     6961 atcattacta aaagagttac aaccttttac ggttaatgtc cgcgagaacg atcctctctt
     7021 tgagacaaca aaatcttatc taaatggtca gattctggtt ttgacgtcgg agtattatga
     7081 cacggaaaga ggagttaaat acgattcagc tagcttttac ttctaactca aaacgaaagc
     7141 agattaacaa aaggttgtta gaggaccttg ttaacctgcc aatcatcatt aataattatt
     7201 atcaatttag actatttaat aaaattagat tacaaaaaaa cagaaggagg aaagtagctt
     7261 gtacagatct agagacttct acgtgagagt aagtggtcag cgagctcttt ttacaaatcc
     7321 agccacaaaa gggggatcgg aacgctcatc ctattcggtt ccgactagac aggcactgaa
     7381 tggtatcgtt gatgccatct attataagcc gacctttact aatatcgtca cagaggttaa
     7441 ggttattaac cagattcaaa ccgaattaca gggtgtcagg gctctgttac atgattatag
     7501 tgcagattta agttatgtat cctatttgag tgatgttgtt tatctgatca agtttcattt
     7561 tgtttggaat gaagatagaa aagatttgaa ctcagataga cttccagcta aacatgaagc
     7621 cattatggag cgttctattc gtaaaggggg acgtcgagat gtgtttttgg gtacaagaga
     7681 atgtttaggg cttgtagatg atatcagcca agaagagtat gagactactg tgtcgtatta
     7741 taatggtgtc aatatcgact tgggaatcat gttccattcc tttgcctatc cgaaggacaa
     7801 aaagacacca ttaaaatcat actttacaaa gactgtgatg aaaaatggag tcattacgtt
     7861 taaagcacag tctgaatgcg atattgttaa cacgctttct agttatgctt ttaaagcacc
     7921 agaggagata aaatcggtta acgatgaatg catggagtat gatgccatgg agaaaggaga
     7981 aaactgatgg atttttttac ttctctcttg aagacttatg aaaaagcaga gctagcagac
     8041 ttggttgatc accaaaaaag aagtaatgag ccggttttac tgccgattta tcatacgagt
     8101 ttaaagtcaa atggcaaaaa tatcatttca gtgaaacttg acaaagatgg ccagtttcac
     8161 aaggcagaat ttatggcaga taagcaaatg attatttttc ctgtaacggc tgattctgtt
     8221 gctaggtcag gtagtcatcc tgcaccgcat cccctagtcg ataaatttgc ttattatagt
     8281 gctgaaatgg ggcagtctca gtatgattct tttcataagc aacttaataa ctggattgat
     8341 tattgtgagg agggtgacgt caagaggttt ttaaccattg ttcagcaatt tattttgaaa
     8401 ccagaatttc tgacactgat tctcgattct ttaattggtc ctgattatca aaataatcaa
     8461 ttaaaagtca cattttgtga tgccactgga aaagaaaaat taattgattt atcagcttgc
     8521 tttttagaat tttcaattga tcagttccag ggctttaaaa atgaatcggt ttcgacattt
     8581 aaaactttac accaatccta tatttctttt gttgaagcca atcgtgaaaa gcttggtatt
     8641 tgtaatatta gtggacgaga ggaacagctt accgataagc atagaggttt gatggggaat
     8701 gctaaaatca tctctgttag taataaaaga gaagcttata aaggacgttt tagagaacgt
     8761 gaagatgttt ttagtgttgg ctatgaaact tccgaaaaga ttcatttaat gctcaagtac
     8821 cttttagaaa ataaaaatac cagtacttgg ttagggtctt ctcaatattt aatcaactgg
     8881 tttagtgatg atttaacaaa tgatagtcgg ttggatatcg tatcaccaat ctttgatgac
     8941 ggacttgaag aagatgatga tgacgatacg cctcctgtta taacattagc aactgaagac
     9001 aataaaagaa ttggtaaatc attcatcaag ggacaaaaat tatttgctaa tgatgccact
     9061 tactacgttg ctattttgaa taaaaccagc aatgggcgga ttgctttaaa atattttcgt
     9121 cagcttcaag cgtcccaatt actcaccaat cttaacaagt ggcaggaaac atacagttgg
     9181 gagtcgcgat ctaagtttgg aaaaagtcgc ttaagaaccc ctacttttca tgacatcctt
     9241 aatgtgtcct acggggttga tagggatcgc ttccttgaat tagataatga taacttcaaa
     9301 agtgatcaaa ttcaaaagtt agtggcaagt ttgattgatg gtaaaccgat gccacagtcc
     9361 attgtcaaaa agttaggtaa caatgttaaa gaacgacatc gttaccgtaa gcactggtat
     9421 caagttgagc aggtctgctt agcaatttta cacaaacaaa atggggagga attttcaccg
     9481 atgctagatc ataccaatca aaatcgttcc tatctttttg gacgattatt agcaattttt
     9541 gaattaatcg agaccttgcg ttatggcttg gatggaaaca ataacgaccg tattaccaat
     9601 gctgaacgtt attggacagc ctatactgga caaccaacaa aattgatgat gttattggaa
     9661 aataaaatta agccttacga agaaccattg aaattaaatc gtcgtggcag ttggatgaaa
     9721 ttagaaaaag aaaaagaaga gattttagaa ctgttaaatc ctctgttaga aacagaaaca
     9781 atggaaaaac ccttagatta ccgctttatt tttgggtatt atgctgagaa aaactattac
     9841 tatacaaaac aaaacactga agtaacagaa agtgaggagt aaaaagatgt tggaacacaa
     9901 aattgatttt atggtaactc ttgaagtgaa agaagcaaat gcaaatggtg atcccttaaa
     9961 tggaaacatg cctcgtacag atgccaaagg atatggtgtg atgagtgatg tctccatcaa
    10021 acgtaagatt cgtaatcgtt tgcaagatat ggggaagtct atttttgtgc aagctaatga
    10081 acgtattgaa gatgactttc gttcactaga aagacgcttt tcacaacatt ttacagctaa
    10141 gacacctgac aaagaaattg aagaaaaagc aaatgcatta tggtttgatg ttcgtgcttt
    10201 tggacaagtt tttacttatc tgaaaaaatc aattggggtg cgtggaccag tttccatcag
    10261 tatggctaag tccttggagc caattgtcat ttccagcctt caaattacgc gtagtaccaa
    10321 tggtatggaa gctaagaata atagtggccg ctcttctgat acgatgggga caaaacattt
    10381 tgtagattat ggtgtgtatg tacttaaagg ttctatcaat gcttattttg ctgaaaagac
    10441 tggtttttct caggaagatg ctgaggctat taaagaagtt ttggttagct tgtttgaaaa
    10501 tgatgcgtcg tctgcacgtc cggaaggctc tatgcgagtt tgtgaagtct tttggtttac
    10561 gcattcaagc aaactgggga atgtttcaag tgcgcgtgtc tttgacttgt tagagtatca
    10621 tcaatcaata gaagaaaaaa gcacttatga cgcttatcag attcatctaa atcaagaaaa
    10681 attggctaaa tatgaagcga aagggttaac ggttgaaatc ctagaaggac tctagtatgg
    10741 tctatgccga agatgattat ttaatgctat caggtattca gcatttccaa ttttgtaaac
    10801 gtcaatgggc gttgatccat attgagcaac aatggcttga taatgaagcg acagcgcatg
    10861 gacaggtttt acatactaaa gcagataacc cttacattaa agaaaaacga aaagagcttt
    10921 tggtctcacg tgctatgccc atttcttctg cagaacttgg actttcagga attatggatg
    10981 ttgtggaatt ttataaagat gatcaaggtg tgtctttgag gggaaaacgt gggaaatggt
    11041 taccaaaagt tgtggaatac aagcgcggaa aacctaaaaa agataccaga gatattgtcc
    11101 agttggtggc tcagaccatg tgtttagaag aaacgctaga ctgcgacatt aacgaaggtt
    11161 gtctttatta ccatagtgtc aatcaaagag tgattgttcc tatgacatca gctttgcgtc
    11221 aagaagtgaa ggaattagcc gcagagatgc aagaggttta tcagagtcaa atgctaccta
    11281 aagcagctta ttttaaaaac tgtcagcttt gttctttagt cgatatttgt aagcccaggt
    11341 tgagtaaaaa aacaaggagt gtgtcgcgtt acatcaatga ggctatgacc agtgaggaga
    11401 tggacctatg aaaaagttgc taaatacctt gtatttgacg caagaagatt tttatgtcac
    11461 taaagagggc gataacattg ttatcaagca agaaggtaag gttctcaaac ggtttccgtt
    11521 tcggattatt gacggtattg tctgtttttc ttatttgggt gtgtcgcctg ctttggtgaa
    11581 gttatgtacg gagaatcaga ttaatttatc gtttcataca ccacaagggc gtttttgtgg
    11641 tcgctatatt ggttcaacca atgggaatgt gttgttgcgt agagaacatt atcgtttatc
    11701 tgatcgtgag gaatctttgg aatacgcaaa gcggtttatt ttggctaaaa tttccaactc
    11761 aaggaaatac ttgctacgct ttaaacgaga tcatcgtcaa cagattgata ccaagctttt
    11821 tgaggctgtt aatgacgaat tgatatgggc tttagagatg gttcaggcag cagataataa
    11881 agactcttta agagggattg aaggccaagc tgctaatcag tattttcgca tatttaatga
    11941 cctggtgttg acggacaaaa aaacgtttta cttccaaggt cggagtaaac gaccaccctt
    12001 agattgtgtt aatgccctct tgtcttttgg ttacagttta ctgacctttg aatgtcaatc
    12061 tgccttggaa gctgtcggat tagacagtta cgttggtttc tttcacacgg atcgtcctgg
    12121 gtgtgctagt ttagcgcttg atttagttga agagttccgc tcatatattg tagatcgttt
    12181 tgtcttttca ttaattaata aaggacaact tcagaaaaaa cactttgagg ttaaagaaaa
    12241 tggtagtatt ttaatgacgg aaaatggcag agctattttt attgatttgt ggcagaagcg
    12301 taagcatact gaggtagaac atccttttac aaaagagaaa gtaaaactta tgttattacc
    12361 ctatgtacaa gcgcagcttt tagctaaggc catacgagga gatttagaaa gctatccacc
    12421 ttttatggtt taggagatgt tatatgatgg ttttagtcac ttatgatgta aatacggaaa
    12481 cacctgctgg tagaaaaaga ttgcgtcatg ttgccaaact ctgtgtggac tatgggcaac
    12541 gtgttcaaaa ttctgttttt gaatgttctg tgacacccgc agaatttgtg gatataaagc
    12601 accgcttaac acaaatcatt gatgagaaaa ctgatagtat tcgcttttat ttattgggga
    12661 aaaattggca gaggcgtgtg gaaacacttg gtcgctcaga cagctatgac ccagataaag
    12721 gtgtcttatt attgtaaaaa tctcttgtgc gaagctagct ttcacagaaa caccttgctt
    12781 gctcgcgcaa aaataactta aaaaagaagc gaaatggaga taaaaaggct taaaacacct
    12841 ctatgtgtgc catccgtttc tctataaact gtgtcatttg gcgcagtctc acccttcatg
    12901 ggtgagtgga ttgaaataaa taattacatg actagccaat acacccacat agtctcaccc
    12961 ttcatgggtg agtggattga aatttcatga gcttctttac tctcaaagta agagtggtct
    13021 cacccttcat gggtgagtgg attgaaagat gaacccgacc tctcttttaa tgaggtcggg
    13081 tttttacatg cctttagtca accatttatc tgatagcgta tcaaattcaa gtttttgcat
    13141 gttctagtct atggtttgcg ccactagctt tcggtaaact aagggtaact taagagagga
    13201 gttatttatg acactatcac ttgtattaat ggtatcggtt tttggggcag gcttgttatc
    13261 ctttttctct ccgtgtatct ttccggtcct tcctgtttat ttaggcattt tactggatgc
    13321 agatgattca aagacgatta ctatatttgg taaaaaactc tattggtatg gcattgtcaa
    13381 aaccttagcc tttatttttg gtctatctac tatttttgtg attttaggtt acggggctgg
    13441 ttttttagga aatatccttt atgcggtatg gtttcggtac ttactgggag ccttggtcat
    13501 tatcttgggg attcatcaga tgggcctcat taccattaag agcttacaat ttcaaaaatc
    13561 actgactttc cataataaca agaatcgcaa cggtttgttc aatgcattta tccttggttt
    13621 aacctttagc tttggttgga cgccttgtgt gggacctgtt ttgagttctg ttctagcttt
    13681 ggtggcttca gggggaaatg gtgcctggca aggtggcgtt ttgatgatta tttatactct
    13741 tggattgggc attcctttcc tactcatctc ttttgcgtca ggcattgttt tgaaacagtt
    13801 taacaagctc aaaccccaca tatttttact gaaaaaagta ggaggcgttc tgattatagt
    13861 catgggaatc ttgcttatga caggaacctt aaataactta gcacaacttt ttggataaag
    13921 gagaaacaca atgaaaaaag gactattagt aacaactggt ttggcttgtc tcgggctact
    13981 aactgcttgc tcaacccaag acaatatggt taaaaaggaa ataactcagg acaagatgag
    14041 catggcagtt aaaaagaaag ataagatgtc aacatcaaag gacaagtcca tgatggcaga
    14101 taaatcatct gataagaaaa tgaccaatga tggtcctatg gcgcctgatt tcgaactcaa
    14161 aggcatcgat ggtaaaacct atcgcttatc agaattcaaa ggtaaaaaag tttatttgaa
    14221 attttgggcc tcttggtgtt caatctgttt atcaaccttg gcagataccg aagacctggc
    14281 taaaatgtca gataaagact atgtggtctt aaccgtcgtc tcgccaggtc atcaaggaga
    14341 aaaatcagaa gcagacttta caaaatggtt ccaaggaaca gactataagg acttaccagt
    14401 cttgttagat ccggatggca agctattgga agcttacggc gtcagatctt acccaacaga
    14461 agttttcatt ggaagtgatg gtgttcttgc taaaaaacac attggttatg ccaaaaaatc
    14521 agacatcaaa aagaccctta aaggtataca ttaggaagga ccagctgata ggcattagaa
    14581 aaaaggagtt gagtttatgg aacacaaatg gaaattatgg ctatttatcg ttggagtggt
    14641 cttgttaata ggcggagctt ctgttctcat tcagaaaggt caagccaagg cttttagtca
    14701 aggcaagcct caactaccag ctaaaaaagt caaatccact aaagtagatc ccaatgcccc
    14761 tgttgatcaa aaagtgattt acctggctgg aggctgtttc tggggcgttg aagaatattt
    14821 ttcacaagtg gatggcgttc tagatgcggt gtcaggctat gccaatggta gaggcgatac
    14881 caccaactac cagttaattc atcagactgg tcatgcagaa accgttgaag tgacctatga
    14941 tgcgaaccgt attagcttga aagaattatt actgcatttt ttccgaatta ttgacccaac
    15001 cagtcttaat aagcaaggaa atgatcgcgg tagtcaatac cgaactggga tttactatac
    15061 tgacaaagca gatttagcta ttattgatga ggtcttcaaa gaaaaagcca aggattacaa
    15121 gaaaaaaata gtggttgaaa aagcaccatt gaaacacttt attaaggcag aagactacca
    15181 ccaagattac ctcaagaaaa atccaaatgg ctactgccat attgacatca accaagcgac
    15241 ttatcctgtg attgatgaaa gcaagtaccc aaaaccaagt gccactgaga tcaaagcaaa
    15301 actatctgca gacgaatacc gagtgacgca aaaaaacgaa actgaaaaag ccttttctaa
    15361 tcgctactgg gattcttttg atgcaggaat ttacgtagac gttgtgacag gagaaccgct
    15421 tttctcttca aaagacaaat ttgaatcagg ttgtggttgg ccaagtttta gccgccccat
    15481 cagcccagac gttgtccgct acaaggaaga taagagtttc aatatgacga gaacagaagt
    15541 gcgcagccgt tcagggaatt ctcatctggg gcatgtcttt actgacggac ctaaagacca
    15601 aggcggcctt cgttactgca tcaatagctt gtctattacc tttattccaa aagctgatat
    15661 ggaagctaag ggctatggtt atttattatc atctgtagaa tagggttagg cctaaaaatc
    15721 tgatataata taagattacc tctcagaatc attgatatca aggctttttt aaagtctaaa
    15781 aacagactta ctacgtttcc cactacgttt gtgttaaata gcgacgagtt cggccaattt
    15841 gtcagcaaca ttatcctttg attttttgga caagtgagta tataaatcca tcgtgattgc
    15901 tattttagcg tggcctaacc gctcttgtgc aatcttagcg ggaatcccag cctcaaacaa
    15961 caacgaagcg tgggtatgtc taaacccgtg gggagtaatc ctttttaatc catgcttcaa
    16021 tataaatctg tccagtcttt ttctcacggt gtcgctagca aaattaaaca atttaaacga
    16081 tccgtgtaaa ggtttgatac tttgcttaat atataatttg gctaacgaca tggtctcagc
    16141 gtccattgat atagtgcgat tgcttttttt ggttttagga gattgtacag cccatccttc
    16201 ttttgtataa gcaatggttt ttgtaatgct gatagtattg ttgcggaaat caaagtcggt
    16261 atcttttaaa gctattaatt caccaatcct aaaaccgcca taactcagca atctataaat
    16321 cagacgcatc tctagagttt cttcagcttc cacaagcctc aagaaagtat tcaattcctc
    16381 ttttgtgtaa tattttttgg tgagtgtatc cacgtttttg taagtgcact ttgatctcaa
    16441 cgtcttgttc attgggttgt tatcaataat acctaagttg acagcaaatt taaaaattct
    16501 gtttgctaga cttagataaa gcgtatatcc gctatatcga gacaggcaat tcacaaattt
    16561 ttgacaaatc atgacagtta tcttcgtcat ttgcagttgc cctaaatgtg gctttaaaat
    16621 tgttttatag taattttggt taaccagaaa tgttgacggt ttgactgtat tttggtactg
    16681 ctcaaaccac agtttagcta catcgtcaaa tgtagtttta tcattacttt tccaagcgcc
    16741 ttgacgctgg aaatcatcaa taagttttac ctcggctctt ttagcttctc tttctgtttt
    16801 aaaaccttgc ctagttgtcc tgacttgttt accagtcacg ggatcaaccc caaggtatgc
    16861 tcttaagcga taggcagttg tgccatcttt tttagtgtat ttttcaatca ttgtttttcc
    16921 tctctctttg cgctggggag tgctgatttt gagataggat attggcatca cctcctttgt
    16981 gtgatataat tcagagtata agaaaatgag ctatttaaag cttacttctt attgattgca
    17041 tattgcctta cgctctcctc gtccaaaatt tgagcgtagg gcttttttat ttatctaaaa
    17101 gtaagtagcc atctatataa attagaggga cactattctc agaaccactt gttgtcgtat
    17161 attcataaga taataaatat cttccattga tagtgatatt atcagtttct aaaagtttag
    17221 tttctagtcg cttggtttcg ataaacaaca tatacaagtc cccgttaggg gtgtttgcta
    17281 gcattttagt atatttatct ttatcagaga tttgtattat ttttaaatta ttgattctga
    17341 ccttaaggga aaagtacttt ttagggtctc ttaaaattgt tttgtagtca taaaatagat
    17401 actcatctga tttgtagtta tctgttgtta ctttatcaat cttagatatt agagtatcaa
    17461 agtattcttt ttcgctcata tctccagata ctttactagt atccgatgag ggagtctttg
    17521 atgttgtatc tttttttgag ccaccagtgc aagctccgag acatactatt aagactgata
    17581 aggtaaacaa atatactatt tttttcacaa taaatcccct aaattaaatt tttaaattct
    17641 tctttaacca tcacttcgtc agcgattgag gtcagttcat acttttccat gaattggatg
    17701 tagttgaaat cctccatatt atcccaatag gatagctctt cttttaagag atgatgtatc
    17761 atacacctat cagcttgtag ctctgctttt tctttgttta gcttgtaata actcgcagta
    17821 tgttctctat gtcctagttc gtgatagatg actttgtgtt tatatatacc gtcaagataa
    17881 gtgtcaatcg caatgacgtt gtgtttttta ttaaacattc cagggatatt tgtaccccta
    17941 ccgtcaaagt aaactaaatc gattcctttt tcctggcaga ctgtttctgg tgtcatcata
    18001 gagctgccct ctctattttc tatttttgat gcgcgtttcc aatatagatg tgataaggtc
    18061 tatatcctcg tcgttgagtt cgtgtccgtc gaagaagaag gtttcttctg catctttttt
    18121 tagatcgatt gcgaccgaag tgtgcccatc ttgagccatc ttaggattat ctgtcctgcc
    18181 aagtaaatag tcggtagaaa cattaaagta gttagctatt ttttctattg ggtctgtatt
    18241 agccgttttt ttacttttta aattataaat gtagttttca ctcagcccta tatcagttgc
    18301 gaccttttgg agagatactc ctcttttttt agctaaggct tcaattcttg aatacacctc
    18361 aaacattgtc atatcaacct ttctgaaagt atgacaaaaa aaatttaact ttttcgagta
    18421 aaaaatattg acttagttca cacgatagag taaaatagtt tttgtaagat agttagttag
    18481 taaaaaacga agttaaactt tttacaaatc ttttaaaagt agttggggaa ctgcgcaata
    18541 taaaagagtt ataaaggtta taactaggtt tttcttatgc tttcatttta cattaacgtg
    18601 taaaataagt caacacaaaa atgttatttt tttactaact ttcttgctta caaaaataaa
    18661 acaccaccta gctgctatct agatggtgct acggaaatta ttctgctcaa taaaaaacac
    18721 tctccgttat tacacattgg aaagtgttta caagttttta ttaagactga gcaacaggtg
    18781 taaactgttg gctgaaactt cgtcggtcct gcttccgaca ctgctttcat catgtataag
    18841 ctagtccttg gacgccactc ggcagttatc tgacaggcct gctataagtc gcgctgcagt
    18901 cgcccttata gtcagcgtca ggctccgtgt gttaaacgtc ttcgataaaa aacattgttg
    18961 ttacctagct tatataactc atctagtcac agtacctttc aaaaattttg ccaatttgca
    19021 tcaactcctt ttttgtaata aaggtacttt cattataagg ttgtaagtca aaaaaatcaa
    19081 gatggttaca aaaatcattg agcagaataa cgatttccgt atattttatt aatattttct
    19141 acttattttt gaaaaggagg tatataaatg ccagataacg caatcgccat cgaaaaaata
    19201 aagaagtatt tgcttgataa caatcttaaa caagttgatc tagcagttac ttatggcaaa
    19261 gaaccgcaag atgtggcgaa tattcttgct ggacgaaaaa aagacccagc atcaaatcgc
    19321 tttgtcttaa aagttatttc ggatttaaaa atcagataga aggaataata tgaataatct
    19381 tatcacagta acactaaacg aaaaccaaga acctattgtt tctggtcgag atttgcatca
    19441 agcattagaa attaaaactc agtacacaaa atggttagaa cgaatgtctg attatgggtt
    19501 tgaagaaaat gaagactatg tagctattag tcaaaaaaga ctaacagctc agggcaatca
    19561 aacagaatat acagaccacg ttctaaaact agacatggct aaagaaattg cgatgcttca
    19621 acggaacgaa aagtctaaac aagtccgcaa atactttatc caaatcgaaa aagacttcaa
    19681 cagccctgag aaaatcatgg caagggcgtt gctgatggcg gataagaaag tgcataaact
    19741 tgaagcacaa atcgaggcag accgtcccaa agtactattt gctgatgctg taagtgctag
    19801 caaatcatct tgtctgattg gtgagttagc taaaatcctg aaacagaatg gagtcaatat
    19861 tggtcagaat aagctatttc agtggttacg agccaacggc tacctaatca gtcgccgtgg
    19921 tgagtcttgg aatcagccaa cgcaaaaaag tatgcagctt ggattgtttg aactcaaaaa
    19981 aacagccatc aatcactctg acggtcacac tacaacaaat gtaaccccaa aagttactgg
    20041 taaagggcaa caatacttta ttaataaatt ctttaaccag gaatatctgc cagtttagaa
    20101 acgtaacaaa actaacgaag ggagaaaagt atgccagagg atttaatcaa acaactagaa
    20161 gctggttcag aatttctagc aaagacatgt ttacatagca agattattat cacggtggat
    20221 ggtattcggc ttgtggaaac aaaagagttc cacccagtga gcggaactct actagattag
    20281 acaatacgtg tataagtgtg tatcttagct aatctatgaa tatttgagcc aacagaccca
    20341 acaagaacag aacggtattc cgtttggctt acattgtgat aatggtaaat agaaccatta
    20401 ttaaactcaa cttccaaagt gttattttcc caatcaacac ttcgggcgtt actagatgaa
    20461 acgtattgac gttgcataac ttttcctcct ttcgtaatga tagctttatt atagcacgca
    20521 ggaggaacta cacagataga aaggaaaacc acatgagacc aaaacgatat ccgtatagcg
    20581 ggaagaaaaa cagaaaagca aaagacatca gtctcaagct gatgtctaaa gaggagttat
    20641 ctgattttag tcgtcagatt gctgaagcca ctcgtgatag tgtcgaacca tttcgagagc
    20701 cgcaaagtat gatgagctaa gtattaactt ttcaaggttt acagatcccc cttcgctttc
    20761 tttcgcatat ctattgtaat ggtactcaat aacttccaga atttcttcgg ttttaccatt
    20821 gcttagagat tgggcgaaat tgttgaaatc tttattcata taatcacctc ctttcgagat
    20881 gattatatca aaaaaagtcc gacggcaatc ggactctaaa gaatactatt tacttagatt
    20941 ataccacgaa aggggtgata aatctatgca atcacaactt acttacgatt tactaaaaaa
    21001 gcagatagca gaagagcttt ttgatgagtt taagaaactc atacaggaaa aagatttagc
    21061 gaatcagtgg gtcaatcaaa caacgctcgt caatgaatac ggctactcat ggcaaactat
    21121 aaaacgcatg gagagctatg gccttaaatc ttttaaaaac ggtaaagaca aaatgtattg
    21181 tcttgctgat gtcaacgaaa tcaaacactt aatgaaacaa taagcgctgg ggagtgctag
    21241 aggagcgtaa catgaacaaa ttagaactat ttttattaac aacaacgatt atcttagcaa
    21301 tcattgcaag aattcaatat gaagtcatca aaaaacacaa ctcgccagag aataagcgaa
    21361 aaatttttag ggaagtagct ttagaaaaca gcaaaggatg gagcgagaag cgctctagag
    21421 gagaggtggt cagctgatgc agtacatttt tcaagacgct acgaggtaat tttactagtg
    21481 ttagtaatga gtttattgat gataaagaac tatcttataa atccgttgga ttgctattga
    21541 ccatcctaag aaataaagat gagtggcgag tatacccaga agagcttgct agaagacatt
    21601 ctgatggttt agcttctgta agagcaggcc ttagagagct tgagaaggca ggatatgtta
    21661 gaacttacaa aaagataact aggcgttctg agggactgca acattaccgt ttctgttcgg
    21721 attgtaagat tagtgatgaa gtttttcagc gattagttga gcaattaaaa aatgaactct
    21781 ccgactaaaa tgcgattttc taaagttaga aaatctaaag ttagaaaatc taaagttaga
    21841 atttcgcaca ctaataaata ctaacattaa ataaatacta aataacaata aatactaaca
    21901 gacaataaga tgatgaagaa gaaaggagaa gcattggaca aaaaagaact gtttgataat
    21961 ttccaaaata attggatgcg tctcttatca ccatttgaga ttgaagacat taataagtgg
    22021 attgacgaag agaagatgcc tgttgaagtt gttaacgagg cactaaaatc gacaattcta
    22081 tacaacgcac caaaccttag atacttaaac agagtcttga acaactggaa gcgacaaggg
    22141 attgatacag tcgagaaagt cgaatttgct aggttgcaat ttgaaaataa aaagctcagt
    22201 caaaataaaa atcatcaatc caacgtccca agctggtcga atccagacta caaagaacca
    22261 gatttaaaag aatttgcact aggaagcata gacggtatag aagatggatc aggagatttt
    22321 taattttttt aacaaacaaa tcaaaaaaga ttttggtaaa acggcgagta aagagacttt
    22381 tgctaagttt gctagttact gcgccgaagg aatcgaaaaa aaaggagtta agccaatttt
    22441 taattggata aacctatacg cattcggcct tggaataaca acggcagaag cagaccgatt
    22501 gagaatagag cgatataaac aggagaatgc gttatgacaa aacaacatag agagacgctt
    22561 atctggtacc gagcaagcca tcaagagcgt gagagattgc ttgatttcgg gttagttgat
    22621 aaatcacagt acgtgacact attgcggcaa ttgcgcaaga aatatgcgat ttaggaaggg
    22681 atatatggtt gaaatcagaa ttaacggtga gctcgtaacc tttgacagca attttagaga
    22741 tgcgcttatc tttacgattg actgtcttag aggtagcgaa gaacctacgc taaaacagac
    22801 ttatcaaacc tttaaagact acacagacga agacttgatg gactacatcg agacggaatt
    22861 tgatgtatgg ccagagctaa tcgttaatcg caagattgac agcaagtggt ccactaaaca
    22921 acacattttg gatgattaaa atacagaaag aggaaataac atggcttatt tatatgaact
    22981 tgagggaatc gccgcttatc tggaaagttt agatttagac gacgaaacct ttcaaaatac
    23041 gcttgacagc attgattttc aatcagactt agaaaatacc attgagtatt ttgtcaaaat
    23101 gttaaaaaat gctcaagctg acgtcgaaat gtataaagcc gaaaaagaag ctttttacaa
    23161 aaagcaaaag caagcagaag caaaagtgga aaaatacaaa gagacaatca ggcgtgcaat
    23221 ggaattgagc caaaagaaaa aagttgacgc tggaatgttt aaggtgtctt tgcgaaaaag
    23281 caaaaaagta gagattttgg acgaaacaaa aattcctctt gattacatgc aagaaaaaat
    23341 tgaatacaaa ccaatgaaat ctgagatctc gaaagctttg aaatctggaa ttgatatatc
    23401 tggagttgaa ctaatcgaaa cagaaagttt gcaggtaaag taaatgagga aatcagaaag
    23461 tataacagaa tatgctaaag ccttttgtaa agctcagcta gaggtaaagc aaccgctaaa
    23521 agataaagac aacccctttt tcaaaagcaa atacgtgcct ctagaaaacg tgacggaagc
    23581 gattacaaaa gcctttgcta ataacgggat atctttttcg caggatccaa caacaaacgc
    23641 agaaaacggt tatatcgatg ttgcaacgct agtcatgcac acgagtggcg aatgggtgga
    23701 atacggacct ttaagtgtta aaccaacaaa aaatgatgta caaggcgctg gttcggctat
    23761 cacttacgca aaacgctacg cactatcagc aatttttggg ataacaagcg atcaagatga
    23821 tgacggcaat gaagctagca aacccaacaa aacaaatcaa tcgcaaaaac caacaaataa
    23881 aacgtcaaaa ggggcaagct tccaaacccc gaaaatcagc aatatccaag tagagactta
    23941 taaatctgat ttaagcgata ttgcaaaagc cacaaatcaa aatgtcgaag agctaacaaa
    24001 atggctaaca gataccttaa aagttaaaac actggaagat ttacgcacag aacagattgt
    24061 atcgactgat aatttgatta ataaattaaa aaagaaagca gagcaaaaaa atgattaata
    24121 atgtagtact agttggtcgc atgaccaagg acgcagagct tcgctataca gcgagtcaag
    24181 tagctgtagc tacgttcaca cttgcggtaa accgcagatt taaagagcaa aacggggaga
    24241 gagaagcaga tttcattaac tgtgttatct ggcgacagtc tgctgaaaat ttagccaact
    24301 gggctaaaaa aggtgctttg atcggagtta cgggtcgtat tcagacacgt aactacgaaa
    24361 accaacaagg acaacgtgtc tatgtaacag aagttgttgc agataatttc caaatgttgg
    24421 aaagtcgtaa tcaacaatct ggtcaaggta actcttcgca aaacgataac agtcaaccgt
    24481 ttggcaattc aaacccaatg gatatttcag acgatgatct gccgttttaa atgatatggc
    24541 taacagatat agacaaagga tatatgcggt ttacgacgga gactcttttg tagatgttgg
    24601 cacaaagcat gagctagcag aaagacttgg tgttaccgct gacacaatag tttttatagc
    24661 gtcgccagct cataaaaaga ggagaccgga tggcagacac gcagagttta taggatacga
    24721 agacgaattg gaggagtagt ggttaaattt acaataccga ttgagccaaa acctcaaaag
    24781 cgcccacgct ttagcagatg gagcggggct tacgaagaca aagatatgat ggcttggagg
    24841 aaacaagtca cagactatgt taaaaacaat tacgaagggc cttattttga cgacggttta
    24901 aaagttgatg ttacttttta tctaaaagca ccagaattgg tgtctaaaaa gccgtcagag
    24961 cgtgccagag ataagactaa acaaaagtat caggattata taaacgagct cttatatgtg
    25021 ccgaaaaaac cagatttaga caatcttgaa aaagcagtct atgacagcat atcaaaatca
    25081 gaggttgtgt ggacagatga caacatcatt gtcgagcaca ctacgcgaaa gctgtatagt
    25141 ccaaatccta gaatcgaggt aaaaataaac gaattatgac actagtagat gatttttaca
    25201 aacggatgaa gccgtctatt aaaaagtttt tagacaacaa tattatcatt acagatcagg
    25261 aagaagctat cagagtttat aagtcagtca aatactataa aaaactaaac agattgccgc
    25321 cacctgatgt attggagtgg ttccaacaaa tctacacgac agaggaaatg gtggcgttaa
    25381 tcaagcagtc ttaccgtctt aaacaaaaaa agacagacga ggatgacaaa atctacgaaa
    25441 agtgtatgtt taaaaactac ggtgacgtta agcttgccaa aaaagtcaag cgtatgaatg
    25501 cacttgccaa ggcttgggag atgggcttat gaaaagacac agacagttta ataaagatat
    25561 taaatacaca cctaaatctt acaataatct gttgccttac gatgtagtgg aattattaat
    25621 agcccgtaga gacaaaacaa aggtgtctga cgaagtttta gcagacaaga taggtattta
    25681 tgcttggaat ctagaagcgc tcttagaacg cagaatattg ccaaatgaga gcgagtgtaa
    25741 attgattata gattttttga gagaggtgga gagatgctga cggaagatac gtttaaaaaa
    25801 attgaggagc ttgaagctgc ttgtcaggat acgacagata acattaaaaa accatcacac
    25861 tatcaaggca ggcatggcat ggaagcaatc gatgtggtta aaaacttcgg ggcttgtcca
    25921 gagtatgaag agggtttcta ttggggcaat gctgttaagt accttttgcg gtatcacgct
    25981 aaaaatggtg ttgaagacct taaaaaagca cggcagaacc ttgattggtt aatcgaaaag
    26041 ttggaggaag tggaatgaag aaaccaaatc gctatccgta cagtaaatca aaatttaatg
    26101 gttgtattta ccagttgcat tcagccagct ttaaagatga acaatatgtt gaagatttaa
    26161 aatcatgcgg catacattat caaattacaa aaattggtta ttttcctgat atttttataa
    26221 aaattgataa tctcgaacaa ttacaaatat taatagataa aacaggacac gatttaatac
    26281 ttagtaaaga ccaaatttgg atttatgatg actatatgga atgaggagta ataatgatac
    26341 caaaatttag agcatttaat aaaaagacca aaaagatgta tagcattgat ggctttaaag
    26401 caagtgaacg caaaatatac agatgcagct tagcagatga tgagtttcgc tctggttgct
    26461 tagagacgtt tcattttgtc gaggataacc ttgacgatta tattctcatg caatcaacag
    26521 gtctaaaaga taaaaacggc gtggagattt ttgaaggaga tgtggtcgaa tatgacgacg
    26581 gagaatattt gttcgctgga aaagtagtta aaacagtatt tggaacatat gtaaaatctt
    26641 acagtttttt ctcgtttgaa gatttttcgg acgaaaatac aatgaccgca gacgttgaaa
    26701 tcatcggcaa catttacgaa gaaagcgtgg aagaatgaga aaatatattg aatttaagga
    26761 cgaatggaaa agtgcagcag accacctgaa cgattttatc gacaaaaaca agtacgcaaa
    26821 agtgacaggc gacttatggc aaggcagtga tcaagtcatt gctgagcagt gttttttaaa
    26881 agtattagag gagatgcaaa aatgaacatt gaagaagcga aagaattagt agataattca
    26941 aaattttatg gaaagactag cagtgttata aaagccgagg ttcgcgacat tatagaccag
    27001 ttaaaccaac caaaaccaga agtaccgcag tgtgtggcgg attggataga agagtgcaaa
    27061 gaagaagatt taacactatc acttgcctat gatgttgatg cttttggcga agtggcgaaa
    27121 tggctttatg acactaatga tagcacaaac attgacctat ttgcccaagc atggctagct
    27181 tatccaaata tcaccattga aaaagagaag ctgtatacag tggagatacc cgatccaaat
    27241 catgacgtgg gcacagttat attgagtaag aataagcaca gggaagctta cattgcaatt
    27301 gactacaccg gaagttggaa ggaaagaaaa gcaaaccacc tcaccgaatc agaaatccgc
    27361 aaagacttcg attgggcttg gcaatttgcg aaagaggtga ctgaatgact gaagagttag
    27421 gagtgttata tagcgaaaaa tggcataagt attatttata taaaacttgc aggtatatat
    27481 cttatgttga taatccacat caggctacta aatgcacccg caaacaagca gaacagtttc
    27541 cacagtttaa atgggtaccg ctgacaaaat tataacccca cgcaagcgct caagagcctg
    27601 caatggctct gtgggggtgg accgaaatta aaaaatagaa acgagaacct ccttacacca
    27661 aaacaaatct aacgcagatt atcggtcatt tgttattatt caaggcgcta atactgacat
    27721 cgtacgcctg tgtcaaaaat aaaaaaagaa agagagggct tttctccaca aaacaaaaag
    27781 acgtccacac ggaacgcccc cttggttaaa tttaagctta aataaattat accatattgg
    27841 gggctttcat gacgtttttt cctgagattg atatccaaaa aacaaaatcc aatgccaagc
    27901 gtaaattgag agagtatcca cgctggcgaa ggatagctaa tgacgtagat actcaaaaag
    27961 ttacagctac ttactcattt gagccaagac aaccgcatgg agttcctagc aaaccagttg
    28021 agagactagc actaaaccgt gtgtcagcag aacaagagct ggatgcgatt gagagagcag
    28081 tcaacgggat atttgatcca gagtatagat tgatactgat tgacaagtat ttgctcacat
    28141 atccaaagac tgattgtgat atttatacaa aacttggtta tgaaaaaagc cagtattaca
    28201 acatgctaga taatgcttta ttgtcgttct cagagctata taaagaggga atgttgcttg
    28261 tcgagaaatt ggaaaaaagc tggaattaat atggaataat tatgtacttt atatataatt
    28321 attcatgtta ttatagtatt atcaaaataa caagaagaga taacctttta accaattggc
    28381 tatttattta gtcgccaact ttaactacaa tcaaacttgt tattttgtag cctgatggcg
    28441 gtacagcgag ttgagacgac aactgggtat gcaggttcga ttcctgccgt ctcaatcacc
    28501 cagagattac acgctgtgac attgcggaat gtaatcaaag caaaaaggat cacggaactt
    28561 tgcgatgtcc gccgtgaatt aacaccctta tttgacattg gcgttccctt gaggagaata
    28621 cgcaatctgg gttcggtgtt aatgattaag acttagcaat gcctcttgac aatgcgtacc
    28681 agcgctaagt cgatgtcaag gttggacaag acagtgccaa ccgacatatt aaccgcaagt
    28741 ccaaaaccaa gggtcgcaac cttgcttgtg gttagctgat agttcggttg aggattcggc
    28801 cgaagtgagt tgttgcactg tgcacggtgt gataagctat cgtgggctta agttttgtgg
    28861 cgaaacggca ccgttaataa tatttagact gtttatttgg acttgcgttc gcattaggaa
    28921 atactcacta aatattgagt gcagtggcac gttcgattcg tgcaaggtct gtagaagagc
    28981 gtttgtgaga ggtcttagct cttctaaacc tttggaacat gaaccgtgat tggaaaacgg
    29041 taagggtagc gccttgcttc gggacaatag ctaagtccga aaactctttt cgaagagcca
    29101 gaagaagatg tgtcggttcg attccgactg ttcctgttcg ataaatagaa gtgtcccaga
    29161 atggggtagg caataggctt agcattcatt cgctatttat ctatagttaa ccaattagtc
    29221 atcacattgt ggtgactttt tattatgtaa aaaaaggaat aaaacatggg atttgtggac
    29281 aaaaaattaa gtgaaataac accttataaa aataacccta gaaacaatga tgaggctgtt
    29341 ggaccagttg ctgaatctat taaagagttt ggttttaaag tgcctattgt cgttgataaa
    29401 aacggcgaaa tcataaacgg ccacactcgt tataaagcag cccaaaaatt agggctagaa
    29461 acagttcctg ttattgtcgc agatgactta tctgaagagc aaatcaaagc gttcagactt
    29521 gctgacaata aagttggtga gattgcggtt tgggatttag atttgttaaa tgaagaatta
    29581 aatgacattt tagatcttga tatgtctgct tttggatttg aattagaaat agatgacgag
    29641 aatcaagaga atttagatgc tgattttgaa gaaatagaag atgactctgt tttaatagta
    29701 gaagctgaaa gcgaagagga attggaaaag ttatatgacg aatttgtaga aagaggtttc
    29761 aaatgccgag tttcaatatt gtaaaaaaga acgacttaaa tagttctttt aaagtttcca
    29821 aagtaatggc tgactttgat gtcggcgcag aacacgttag agaacatttt attggaaaaa
    29881 tagactatcc cgataaatgg cagataggtt taattgtagg cggaagtgga acaggaaaaa
    29941 gcactatcgc taaagagttg tataacgaag cgttagaaga tgactttgtt tatcctgata
    30001 aacctgttat agattgcata ccatgtcaca atgttgaaga attacaaaaa atgttctatg
    30061 cggttgggtt tgggagtgtt ccttcttggc tcaagcctta tcatgtttta tcaaatggcg
    30121 aaaaaatgcg tgttgattta gctaggcgaa tattaacaaa agagtttatc gtttttgatg
    30181 agtttactag tgttgttgat agacaagtcg ctaaaataat ttgtatagcg ttaaaaaaag
    30241 ctttaaaaag atatcctgac aagaaattta tcgcagttgg ttgtcatcat gatgtaattg
    30301 agtttttaca accagattgg tgttttaata cagatgatat gcaacaggtt tttcgattcc
    30361 cccacgaagc aaacaagaat tcacagtcag aagatgctca attgccgagt ggggaaaatt
    30421 tagacgttat cattatctaa atggagatat agttagagcc gcacgttgtt ttgggctata
    30481 tgatgatgat aaaataatag gatttattgg ggtaatacac tttccacatc ctaaaaataa
    30541 aaaaatcaaa agagttacta ggttggttat tttacctgat tatcaaggtg taggattagg
    30601 tactagattt ttaaaatcag tagctgaaat atattcttgt caagggtttg actttcggat
    30661 tgtcacgagc gctaaaaatc ttattaatgc gttaaataga aatactaatt ggaaattgaa
    30721 aagttacgat aaaggaaata ctccaacggg aaattcttcg attaaacaac ttgcaaaaac
    30781 aactagaaaa aatgttaaaa tagctagctt tctttttata agaaaaaatt aactcctctc
    30841 ttgaaccgtt caaatctgtt ccttataata aaataaaaag gaatgagaaa taatgaataa
    30901 aatagaggct ataatttcaa tcaaacctca atttgtagat gagataatga aaggtaacaa
    30961 gcgttttgaa tttagaaaat cttttttaaa aagtattcct gatagatgtt acatttactc
    31021 tacaaaacct gtaggcaaga tagttggttt ttttaccatt aaacaagttt taagagatga
    31081 accggaaaaa atatggcaaa aaacaagtaa aaagtcaggg attacaaagg atttttttga
    31141 cgaatattat tcaggaaaaa ataaagcggt agcaatagaa atagataggt tgtttgctta
    31201 caaaacacct aagaattatc atgaaataga tataaaaggg aagccaccgc aaacatataa
    31261 aacgatttga agaagctgat tgcttctttt tttattttta aaagtaagga agtgaggcga
    31321 ttggctaatg aagaaaactt aataccagga aataaacgaa gtaagagtga acttagagaa
    31381 atcactagaa aaggcggtat agcttccggt aaagcaagaa gacgcaaaaa agaattaaaa
    31441 accataatcg aacaagcgct caactctgtt atcccaaatg aaaaagcaca aaaaaagtta
    31501 gaaagtctag gttttgatcc aacatttcag tcagctatcg ctttgaaagt ggtcgaacaa
    31561 gcgatgaatg ggaatttaag agctgttgaa ttaatatcta atatatcttt tgcaggaaaa
    31621 gatagcctgg atagaaaaga acaaagacag cgaattaagg ccgcggagct caccacagac
    31681 gagcaacgaa cgcgcatcga gctgcttaaa gtcaaacttg acgcagagaa aggcgctaag
    31741 cctgatacta gcttaatgaa agctttgtta gatgctgtgg aaggaggtga ttagccttgg
    31801 agattatctt ttcaaataaa caaaaagacg tcattagacg ccattttaac tacgaattag
    31861 aggtcaacga gggcacttga cccctcgtag cggaaagacc acagctgggc attttcgtta
    31921 tgctaggtat ctgattgagt cagaagatga aaatcacctt gtgactgctt ataatcaaga
    31981 acaagcttat cgtttgttta tcgacggcga tggtacgggt ttgatgcata tatttgacgg
    32041 taactgcgaa ataaaacacg acgagcgtgg agatcacttg ttaatcacga caccaaaagg
    32101 caataagcgc gtttattata aaggcggcgg taaagttaac agtgttggtg ctattacagg
    32161 tatgtcttta ggatcagtag tattctgcga gattaactta ctgcacatgg attttatcca
    32221 ggagtgtttt aggcgtactt gggcggctaa gctacgttat catctagcag atttaaatcc
    32281 cccagcacct caacatccag taattaaaga tgtctttgat gttcagaaca cgaggtggac
    32341 tcattggacc atggatgata acccaatact aaccgcagag cgtaaacaaa acattatcaa
    32401 cagtcttaaa aaaaatccat atctatacaa acgagatgta cttggacagc gggtcatgcc
    32461 tcagggagtt atttatggcc tttttgacac ggaaaaaaat gttttggatg ctttgattgg
    32521 cgaaccagta gagatgtatt tctgtgcaga tggaggtcaa tcagatgcca cctctatgtc
    32581 ttgtaatatc gtaacaagag ttagagataa cggtaggata agcttcagac ttaatcgtgt
    32641 agctcactac taccacagcg gagctgacac tggccaagta aaagctatgt caacctacgc
    32701 tttagagtta aaagttttta tagactggtg cgttaaaaag tatcagatgc gctatacaga
    32761 ggtatttgtg gatcctgcct gtaaatcttt gagagaggag ctgcataagt taggagtatt
    32821 tactctggga gctccgaaca attctaaaga tgtatctagc aaagcaaaag gcattgaggt
    32881 cggtatcgaa cgcggccaaa acattatctc agatggcgct ttttatctcg ttaatcatag
    32941 tgaggaagag tatgaccatt accacttttt aaaagagata gggctatata gtcgtgatga
    33001 caatggcaaa cctattgata aagataacca tgccatggac gagtttagat acagcgtcaa
    33061 cgtgtttgtg catcggtatt acaactaaag gagttgctta catgggagta atccaaaaaa
    33121 taaaaaatct tgttacaagg agtaaatacg tgatgacaac gcagagtctt acaaatataa
    33181 ccgatcatcc taaaatagct atcagtaagc tagagtacga tcgtataaca accaatctaa
    33241 agtattataa gagcgattgg gatagtgttt tatacttaaa cacggacggc gagactaaaa
    33301 aaagagatct taaccatcta ccaattgcac ggacagctgc taaaaagatt gccagtctag
    33361 tctttaacga gcaggcagag attaaggttg atgatgatgc ggctaacgaa tttattagtg
    33421 agacactaaa aaacgacagg tttaataaaa acttcgagcg gtatctggag agttgtttag
    33481 cgttaggcgg attagctatg aggccttatg tggatggtga taaagttagg gtagcatttg
    33541 ttcaagcgcc tgtttttttg ccactgcaga gtaatacgca agacgtttcg agtgccgccg
    33601 tcgtcattaa gtccgttaag acaatcaacg gcaaagaggt ctactatacc ttgatagagt
    33661 tccatgagtg gcagagctct gatgattatg ttatctcaaa tgagttatat cgctcggatg
    33721 ataaagccaa agtaggtagc cgagtgccgt tatctgaggt atacaaggac ttaaaagacg
    33781 aggcaaaagt tacagatgtg actaggccta tctttactta tctcaagact cctggaatga
    33841 ataacaagga tattaatagc ccacttgggc tatctatctt tgataacgcc aagacaacga
    33901 ttgactttat caatacgacc tatgacgaat ttatgtggga agttaagatg ggtcaacgtc
    33961 gagttgctgt gccagagagc ttgactgctt taactgttcg taccactgat ggcgatgttg
    34021 ttccaaggcc tcgcttcgag tctgatcaaa acgtttatat ccgtatgggt ggcagggatt
    34081 tagactcaag cgcaatacag gacctaacaa cacctatcag agcggatgac tatatcaagg
    34141 ctatcaacga ggggttgtct ttgtttgaga tgcaaatagg tgtatctgct ggattattta
    34201 gttttgatgg caaaagcatg aagactgcaa cagaaatcgt ctctgaaaac tcagacacct
    34261 accaaatgcg taacagtatt gttgctttag tagagcaatc gctaaaagag ttagttatct
    34321 ctatttttga gattgctaaa gcttatgatt tgtaccaaag cgaagttcca agcatggata
    34381 acatcagcat aagtcttgat gacggtgttt ttacagatcg agacgctgag ttagactact
    34441 ggataaaagt tgttaatgct ggctttggca ctcgtgagat ggccatccaa aaagtgctaa
    34501 acgtgacaga ggaaaaagcc caagaaatag ctgcagaaat taatactgga atcgttgacg
    34561 aaatcaatca acagcgcact gatacacatt tatacggaga gtgattagat gaaaaagaag
    34621 cctattaagt taaatgacga acagcttctt ttggaagcta gtcagttatc tgatatgtat
    34681 catcagctga ctcttgattt atttgatcaa gtgattgaga ggataaaagc cagaggctca
    34741 gcgagcttag ccgataaccc ttatctttgg caagctaata agttacatga cgttggactg
    34801 cttaatgcag ataacatcaa gcttattgca aagtattctg gcattgcgga agctcaactt
    34861 cgctatatta tcaagaatga aggatttaaa atttataaaa acacgtctga gcagctagaa
    34921 gaggctctag gtagagagtc tggggtaaac agtactatcc aagacgacct atctaactat
    34981 gctagacaag ctattgatga tgtgcataat ttgactaaca ccaccttgcc atttagtgtt
    35041 ataggagctt atcaagggat aatccaagac gctgttgctg gtgtggtgac aggcttaaaa
    35101 acgcctgacc aagctatcaa tcaaactgtg attaaatggt ttaaaaaggg gttttatggt
    35161 tttacagata aagctgggag aaagtggaga gcagactctt atgctcgtac cgttatcaat
    35221 actacgactt ggcgagtctt taacgaagtc aaagaagccc ctgctaggga gtttggcatt
    35281 gataccttct attactcaaa aaaagctaca gctagagaga tgtgtgcacc tttgcaacat
    35341 caaattgtca ctactggcga agcgagagaa gaaggaggga taaaaatctt agctttatct
    35401 gattacgggc atggtgagcc tgatggatgc ttgggaatca actgcaagca cactaaaacg
    35461 ccgtttgtcg tcggtgtgaa tagtaagcca gaattgccag agcatctaaa aaatatcact
    35521 cctgcacaag ctaaagctaa tgcgaatgcg caagctaagc agagggcaat cgagagatca
    35581 atacgtaaga gtaaagagct actgcacgtt gcgaagcaat tgggtgataa agagttgatt
    35641 aggcaatatc aatcggatgt tagaagtaaa caagatgcac ttaatcatct tgtcaatagt
    35701 aatgactttt tgatagaaag taagtctagg tctaaaatgt ttgttacaga cctgatgaag
    35761 cgtgaaattg tgatgaaaaa agggttaatc aatgatataa taggcttaca gacaagtgat
    35821 ggaatcacta taaaagaaat tagcggacac ctcctggaaa gaatctatga gaggggtgtc
    35881 tctgagagtc acatcgctac tgcattagct aaccctattt acattagacc tgatgcagta
    35941 gatggcggta ggaaagtttc aaggcgctat gtaggcaccc atgttaccgt aaatattaac
    36001 ccacatacag gcaagattat aactacttgg aagactggtg aaaggacaag gaggaagtat
    36061 gacaatcaga gaaatgttga taagtaatca aatattaaat aatgatgata ttgattttat
    36121 gttatctgtc aatcaagatg tctctccttt gtttgagctt gaagataatg acgataactg
    36181 ggatgtatta gtggacgagt tgcagcaaac ctctagttac ttaacgggag atggcgaaag
    36241 tgtctcggat agaactaaga agtttgatga tctagttgat aaaatatcag caatttaatc
    36301 ttataagcat ttagctaaaa actaggtgct tttcttatgc ttaaaaacag gaggaagaca
    36361 tgaataaacg tatcaaaaag aaacgtaaat tggaaacagc ggttgtgtta ttgattgcag
    36421 aaaacgcaag acaagcagaa gcaattaaaa atcaaaacaa acaaatcatg gagctaaaat
    36481 caatcgttca acgaaacgct ctggcaacaa acgaagagtt agcgactgtt aaagctgcta
    36541 ctttagataa tcaatcagtt atcaaggcaa ttggtgacac ggttgactat attaagaaaa
    36601 actacaaacg gaagtggggg aaataaagtt taaccgtgtc gaattcgacc cctttagaaa
    36661 tcaaagtcgt agcaatacgg ctttttatta tgcctttatc cgcaggcgtt aaagaacgga
    36721 aatcagcgac ctatcgcatt tataggaggg aatgcacatg gaaaatgtga caaacgaaaa
    36781 cgtcgaccaa gagactactg acttggaaaa taatcaacaa gaagataaag catttacaca
    36841 agatgatctc aatcgagtgg gaactaaaga gcattctaaa ggctacaaca aagcagtcaa
    36901 agacttaggt tttgatgatg tggagtcagc caaggatgca ctaaaagcct tcaaagagtg
    36961 gaaagagtcg caaaaaagcg agtcagaaaa acagacagaa atcttgaatg ctaaagacaa
    37021 agagcttgag gaagctcggg caaacaataa ggctcttaac gcaaagctag cagcaatgtc
    37081 tttaggtgtg aacgctgaat ctattgatga tgtgattgca ctatctgagc gtcttgtcac
    37141 tgacgagaca agcatagaag atgcaatcaa aacggttttg ggtaagtatc ctcactttgg
    37201 ccaaacaaag gataaagctc ccaaaatcac agtggcaggc aacccgtctg ctgataacgg
    37261 acaaggttcg gtgtctaagg aagactttgc aaagatgtct taccaagaaa aactggacct
    37321 aaaactaaaa aataagaatc tttatgacca attgaaagga aattaaaaaa tggcagtagg
    37381 aacaactaaa atggcacaaa tgctagaccc tgaggttcta gcggatatga ttgacgcaga
    37441 ggtagggaaa gcgattcgct ttgctcctct tgctgaagta gatacaactt tagaaggaca
    37501 accaggtaca actttaacag tgcctaaatg ggattacatc ggtgacgcag aagatgttgc
    37561 cgagggtgaa gctatcccaa tgactcaact tggcttcaaa aagactacta tgaccattaa
    37621 aaaagccgga aaaggtgtag aaatcactga cgaagctatc ttatctgggt atggggatcc
    37681 tgtaggtcag gcagcgaagc aaatcgttga ggctattgac cacaaagtcg atgcagacgt
    37741 gcttgacgcg ttaagtaaat cgactcaaac tgtggaagct actgctacgg ttgatggtgt
    37801 atctaaagcg ctagatattt ttaatgacga agatgacgca gagacagtca ttgtcatgaa
    37861 tccggcggat gcctctaccc tacgtttaga tgccgcgaag gagtggttag gtgctaccga
    37921 ggttggagca aatcgtgttg tctctggtgt ttatggtgaa gttttagggg tacaaattgt
    37981 gcgttctcgc aaatgcccta aaggaactgc ctacatggtt cgcaaaggtg cactacgtat
    38041 catgcttaaa cgtaacacaa tggttgaaac agaccgagat atcacaaaag cgattaatca
    38101 aatcgtagct aataagcatt atggtgttta tctttataag gcagaaaaag ccgtcaaaat
    38161 tacacttaaa gatgccgcaa aaaagtagct aaggctaagg ctgccaagag agaggaagat
    38221 gacgctctcg agtcttagcc gatggaggtg gttattatcg cttttttaac gcaaaaagaa
    38281 tttgaagatt tgggttttga cgatgtagaa gattttgaaa aaatggaaaa acgtgctagc
    38341 cacgctgtca atctttactg tcgtaatcgc tatgattaca aagatttaaa aaaagaaata
    38401 gccctagtgc aaaaggctgt aaagcgggca atcgcttatc agatagcata tttaaatgac
    38461 tcaggagtaa tgacagcaga ggataaacaa tcctttgctg gaatatctct aggacggaca
    38521 agtattagct acactgtcgg gcatggccaa ggcagccaac aaaaaactct ggcagacagg
    38581 tttaatctct gtctagatgc agagaatgag ttactagttg ttgggttggg atatacgggt
    38641 attagctatg atcgataaaa gactgcttat tgacgaactg caggtaaaac ttgtcaaaga
    38701 taaaggtgat tatggagggt ttgtctatga cgaacctttt acactctctc cagttagatt
    38761 tgaccgtaat cttgcaaccg caggtaaaga taatgcaagg caagagacta aaccgtcggt
    38821 tatctttatt tatcctaaat actgtaagac agtagccgat aggtcatggg ttgatgctgt
    38881 tgtcattgat ggtgatactg agtacaccgt tgataaagtg ataccagtct accacccact
    38941 aacaaacaaa attttttgtt ttgaagtgga ggttatctaa tggctaaggt agtggtagag
    39001 ttgggaggca tcaagcgtaa agtatctccg caagcattag ctaaaggaaa gctcatcatg
    39061 aacaaccaag tcatgatgtc catgaaccct tatgttcctt acagagacgg agctttgaga
    39121 ggaagctcga gagctaacag tgtaggtgta acgtggagcg gaccacacgc cagagcccag
    39181 ttttatggtg gtgcttacaa caagtacaag tcctttaaat ttaaaaagta cacaacacca
    39241 ggtacaggca aacgttggga taaacgtgcg ttagctaatg caacaattgt caaggattgg
    39301 gaaaaatcct tactgagagg aatgggattt aaatgacaaa tgactttgca actgttttga
    39361 ggcaatttgt cgaaggatta gacttaggca taaagcctag acttgactat ctaacaagac
    39421 aagaagacct agccatttat ccaatgccag gaggtaaggt aaataacgag tacatggacg
    39481 gtactcgtga gataagcctg ccttttgaga ttgcaatcaa aactaaaaat caggagttag
    39541 caagcactgt gatgtggact attaacagtg ctttgtctaa ctttgactta aaattaccaa
    39601 gtcttaatca ttcgtacaca tttattagcc ttgatgtcga aaagccgttt ttaaatgact
    39661 taagcgatca aggtttttat atttatgtgc tggatattac agcacactta gaaatagaag
    39721 ggaataacta atgagacaaa agaacgccct acgtgggcat tttatcgcac cttatgtaaa
    39781 aggtgaggaa aagacagaag ttacaaaaga gaagcttttg gaattggcta gatggattaa
    39841 agacatctca gacgataccg acgaaaagac agaagatgag gcgtactatg acggagatgg
    39901 aacagaagaa acaaccgttg taggagttaa gggcgcgtac actttcgaag ggacgtatga
    39961 tccagaagac aaagctcaag ctcacattgc aagtcttaag tataagctag gagatgagcg
    40021 aaaagtttgg catttgattg tatcggctga tgggaaaacc cagtggctag gggttgcaac
    40081 agtgacagaa attattgctg gttctggtgc tgccgccgat tttgaagcct ttggttgcaa
    40141 gattacttat aactctctgc caaaggaaag caaggaaatt atacctaaaa aaaatgaatt
    40201 gagcgtagcg atgtgagaca agggtgggct aaaccaccct tttaaggagg aattatgtct
    40261 ggaattgtag ttgacctaaa gcgcacaggg tttccggtca aaattgggca ggtagagctt
    40321 tggtttgata caagccaaga gcgattgatt gagttttttg atattgagac agaagtaaat
    40381 cgtcgcctca atgaatacga aaaacaggtt atcgaagcca acttagacaa cgaaattgaa
    40441 ggtaaagggg ttacgaaaga tgttgcccaa agtgctttag atttggaagc taaatactta
    40501 gaaatcaatt atgatctact attcggagaa ggtacatttg cacagctcta cgcggagtat
    40561 cccgacaaag aagcactcga gaatactctg gaaattgttt gcagggaaat cgaggtcaaa
    40621 ctcaaagagt tagctatcga aagagaaaaa atcgttaagc agaaaacgaa aaagtacaaa
    40681 aaggagtagc ctatgaaact aaacgatcca ttagtagagt cgtttgagtt tagaggtgaa
    40741 atctatccta ttgatttgag ctttaacaag gttttagatg tctttgatgt tattgatgat
    40801 gattttttaa acgaggcgga aaagtgtttt ttgtgccttg atattttgct agataggaca
    40861 gatttacctt ttacttacgc ggtggatctt tgggtttata tcaaaaccaa ttttatcgat
    40921 gcagaaaggc ccgagaaacc tcagctcgac atcaaaggga atccaatgcc tgtagtaaaa
    40981 gaaaaagagg ataacaaaaa agtcattgat ttgagtttag acgctgagtt tatctatgcg
    41041 agctttaggc aaacctacca aatcaatctt ttaaaagagc aaaacagatt gtcttggatt
    41101 gaattcaagg ctcttttaaa tgctcttcca gacgatactg tcatgcagcg tatcatagcc
    41161 attagacagt gggaagatga tggtgaaggc agtaaaaaat acagagataa catgcgtaag
    41221 ctaaaggcta agtacagttt agatgacgga gaggaggaag acgatggcag ctgatggtaa
    41281 ggtaacgata cttgttgacg ttgatggtaa acaggtaaag gtgctcaata gtgagttaga
    41341 taaagttgcc aagcacggtg acaaaggcag ctcctctctt aaaaaatttg cggttggtgc
    41401 aggagtcttt aaattagctt cggctgcagt tgatctggtt agtcaatctc ttggcaaggc
    41461 tatcacaaga tttgacacgc ttgaaaaata tccaagggtg atgaaagcaa tgggccatag
    41521 cgctgaggat gttgcgagat caacagataa gctggctaat gggattgatg gtttgccaac
    41581 aactctagac gaggttgtcg gaaccgctca acgtttgact tctatcacta aagatatcaa
    41641 taagtcgacc aatctcacac tagctttaaa caatgccttt ttagcttcag gagcttcatc
    41701 agaggctgca agccgagggc tggagcaata tgcccaaatg ctatcagctg gtaaggttga
    41761 tatgcaagct tggaaaaccc tccaagaaac aatgccttat gccttacaac aaactgcgga
    41821 agcttttgga tttgcagggg catcggctca aaaggatttt tatgaggcgt taaaaaacgg
    41881 gcaaataaca tttgaccaat tttctaataa gttgattgag ttaaatgatg gtgtcggcgg
    41941 ttttgcagaa ctagccaaag aaaatagtaa agggattgaa acctctttta acaacatcaa
    42001 gaacgctatt gcaaaaggtg tggccaatag cattaaggct ttggatgatt tgtctaaggc
    42061 tgcaacaggt aagggcatag ctgatcattt tgatagtttg aaagttgtta tcaatgcctc
    42121 ttttagcgcc atcaatgcaa gtattaaagc tagtacaccg ctatttaaac ttttgtttag
    42181 tgttattggt gctggaatat cagtcgtcaa agctctgtcg cctgccttag ttggtgtagc
    42241 atctggtcta gctgccatga gggcagttaa tgagactata acaatgatta aagcgctaaa
    42301 tagagcttgg gttatggcat ctgcatcaat gagtattgga gcaacaacca ttaagactgt
    42361 gactgcggta caagcggtaa gtaccacgat gactaaagca gatatggttg caagactatc
    42421 tcagttaggt gtcttaaaag ccagtaccgt gatttatggt gttatgacag gcgctatcag
    42481 tttatctact gctgcaacca tagccggtac tgctgcggta actgcgttaa aagcagcact
    42541 tgtagcctta acaggtcccg ttggttgggt agtaggtgcg attggtgcgt tagttgctgt
    42601 tggagtaagt ttgtggtcat ggctaactaa agagtcagat gagactaaaa agctgaaaaa
    42661 agaacaagaa gggctagttg aaagtaataa acagctaaga gattctgtcc gtgagggcgt
    42721 gcaagagcgt aagaagggcc ttgagtccgt caaagaaagc actgctgctc atcaaaaatt
    42781 agctgatgaa atcattaagt tagcagccaa agaaaacaaa actgcaggcg aaaaacgaaa
    42841 tctgaagaat aagattgacg agcttaatgg atctattgat ggcttgaact tggcctacga
    42901 taaaaactca aactctcttt cgcacaacgc agatcaaatt aagtcacgca ttagcgccat
    42961 ggaagcagaa agcacatggc aaacagcaca acaaaacctg ttaaatattg aacagaaacg
    43021 tagtgaggtt agtaaaaagc tagctgaaaa tgccgagcta cgtaaaaagt ggaatgaaga
    43081 agctaacgtc tccgattccg tccgaaaaga aaagattgca gaactcacag aagaagaagc
    43141 taaacttaaa aatatgcaga ctcaactgca ggaggagtat aacaagacat cagctactca
    43201 acaagctgct gcagacgcta tggctgccgc tgaagaatca ggatcagcaa gacaggttat
    43261 agcgtacgaa aatatgtcag aagctcaacg aactgccata gacaatatgc gcactaagta
    43321 ctctgaactt ttagagacaa cgacatctat ttttgatgct atcgaacaaa agacggcatt
    43381 atcagtagat caaatgaatg ccaaccttga aaaaaataga gctgctactg aacagtgggc
    43441 tactaatttg gagattttgg ctcagcgtgg tgtggatcaa ggtattttgg agcaactaag
    43501 gcgcatgggt cctgaaggag ccacacagac gcaagttttt gtggatgcaa cagatgccga
    43561 gctagcaccc ttgcaggaaa actttagagc agccacagaa actgctaaaa atgcaatggg
    43621 gagcgtttta gactcagcag gtgtggaaat gccagaaaaa gttaaaggga tggtcactaa
    43681 tgtttctacg ggattacagg cggaactgca agctgctaac tttgctcaac ttggccaaga
    43741 aatccctaat ggagtttctc aaggtataag tcaaggggca ggtaaagcaa gtgacgcaag
    43801 tgtcaaaatg ggtcaagaag ttaaacgctc ttttcaagga gagttgggta tccactcgcc
    43861 atcgcgagta tttactgagt acggtggcca tattactgat ggcttgagta atggtgtgac
    43921 aaatggaacg tcaaaagtta tgcaaaccat gcagagcttg gctcaacaga tgtctcaaaa
    43981 aggacagcag attgttaatg acatgcgtag caagtcgaac caaatcacag atgcttttag
    44041 cacgatgagt ggtccaatgc actctcatgg tgttaatgcc atgcaaggtt tggccaatgg
    44101 tatttatgca gggtcggggg cagctttagc ggcagctcaa agcattgcgg cacgtatcac
    44161 cgcaacaatt caaagtgcct tagatatcca ctcgccatct cgtgttatga gggatgaggt
    44221 tggacgtttt atccctcagg gtatcgctgt aggtattgat gcggatagaa aagtcattga
    44281 ctcatctatg caaaagctaa aagagtcaat gacgattaat gcgaccccag aaatagcctc
    44341 tggatttggc ggaggagttg cggggattgc taatcagacc acaaataact caaataacag
    44401 ttttaccctt aatgtcaagg ttgatgaatc cgacggtaat agccgcgaga aatatcaacg
    44461 cttattcaga gaatttagct ggtatattca acaacaacaa ggaaggttag gtgatgttaa
    44521 atgacagctt ttatcaagtt tgatggtaaa aaatcttcag attttgattt gagaattatt
    44581 aatgacgttg agcatgactc gtccttttac gatgttgatc aagttaaggt acctggtcgt
    44641 gatggtgtgg ttttaaagga caataaaagg cttgaggcta ttgaacggtc ttacccttta
    44701 cgtctatata gcaaaagacg actcaccgaa gtagaaactg acataagcaa ttggctgaat
    44761 gtaaaaggtt ggaaagactt agagttgtca tgggagcctg attatatcta taaagcaaca
    44821 catatcaccc cttttagcat aaaggaggtt ttaaggaatt tcggcagact gaaaatcaac
    44881 ttcttaatcc accctatcaa atatttaaaa acaggtaagc aagaggtgcc tctcgttaat
    44941 ggcggtactc tacaaaatcc cggcaatgtt caagctaaac ctatcctaaa aatcaaaggc
    45001 acaggcaatg gtgttttaac cattaatgac tttgagacag ggcttgaaaa tgtgcagggc
    45061 gagcttgtta tagatatgga aaggcaccta gtctataaag atgtcctatc tgcttgggat
    45121 aatatcgtaa gaacagaacg ccaccgcatg ccgttatttg acgttggaca aaataaaatc
    45181 tcgtggactg gtagctttac aattaccgca gtgccaaact ggggggttaa agtatgatac
    45241 cagttttgta tgaggctaag gaaaccaagt ttaggacttt tggtctcggt gagattgcgg
    45301 atgcttatga ggttaaagcc actcgtgagc gcaatggtaa ttactcactg tacatcaaat
    45361 atccgctaga tggtgtcttt gcctcagttt ttaaagagga aatgaagatt aagtctgacg
    45421 ctggtcgtag aaccaaatgg cagacttttg agattaatcg ggtactacga aatagtaaag
    45481 accacatcga gatttttgcg cgtcatatct ctatgcgcac acaggatatt gctttaaaac
    45541 cgtttgtaaa cggtgcgagc gtaggagccg aatcagcttt agaaatctgg aagaaaaacc
    45601 ttgtcggtga tgataagttt gacgttaaaa gcgacatctt aacgcttggt agctttaact
    45661 gggaaattga taaaatcggc aatgcccgtg atgctctagg aggtgtcgct ggctctatcc
    45721 tagatgttta cggtggtgag tacgagtttg acaaccgtac aatcatctta cgcaagcaaa
    45781 tggggcgtaa agctcccacg gtattggagt atggccgtaa tatcgtcagc gtagaggagg
    45841 agcgcttgct agatggcaat tacacctcta tctatcctta cgtaagatat acgccacaac
    45901 caaaaccgca agaggaaacc cctggtaagc cgcatgtagg cgagcataaa caacccgaag
    45961 aacagctggt gacattgcct gaatttatcc tagatggtca gtatctcagc ttatatgctc
    46021 agcgcagaat ccaaatggtt gatttatcaa gtcattttaa cgatgacaaa aataaaaaag
    46081 agccaacgat cgaagaaatc cgaaagctgg ctcagaaata ccttaaggat aataacgttg
    46141 gtgcaccaaa agtcagcatt gaggttgatt atattgactt gtcacaaacg cttgactatc
    46201 aagattttag agtcatggaa gaggttgagc tttgcgacat tgtaccactt tattatccaa
    46261 agtttggcat cacaactgag tctgaaaaag tcgttgagat tgtctatgac gtctatacag
    46321 atagcaatca cacaatcaaa ttaggtacga ttggtcaatc aatctctaaa agtttgactg
    46381 gtggtgtttt tgaacgtatt aatgcgttgg aaaataatca gaaggtaatt actaacaacc
    46441 aaaaacaatt tgaactcaat ctgcctaaat acctcaatga catcaatggt aaacgcgttt
    46501 ggtacgaaaa accagatgac aatattgagc acaagatagg tgattactgg ttcgaaaaaa
    46561 atggtaagta tcagcgcact tggatttggg atggccatca atgggtcaag gtactagata
    46621 cagaggattt aaaccctaac caacgggcct ttgacgaggc aatggctgaa atcgaaaaag
    46681 tcaaaaaagc gcaagaagaa atcaaccagc gcaccgataa agagcttgaa gaatttagag
    46741 ctaccctcaa aaacctagcg ttaccagagg aagcgattaa aaaaatcaca gaggctat
//
LOCUS       DATWEK010000011        44903 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.011, whole genome shotgun sequence.
ACCESSION   DATWEK010000011 DATWEK010000000
VERSION     DATWEK010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44903
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.011"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            108..218
                     /locus_tag="VCR92_000768"
                     /pseudo
     CDS             108..218
                     /locus_tag="VCR92_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_129544913.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            470..2689
                     /locus_tag="VCR92_000769"
     CDS             470..2689
                     /locus_tag="VCR92_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEP4267854.1"
                     /translation="MAKIMNVTGEEVIALAATYMTKTDVAFVAKALAYATAAHFYQVR
                     KSGEPYIVHPIQVAGILADLHLDAVTVACGFLHDVVEDTDITLDEIEADFGQDARDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNETEFYKISHMMKEKRREREALV
                     EAIVSKVKTYTTQQGLFGDVYGRPKHIYSIYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKANGYQSIHTTVYGPKGPIEIQIRTKDMHQV
                     AEYGVAAHWAYKKGVRGKVNQAEQAVGMNWIKELVELQDASNGDAVDFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKESGPIDFAYAIHTQIGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIITNANSFGPSRDWVKLVKTNKARNKIRQFFKNQDKELSVNKGRDLLVSYFQEQGYV
                     ANKYLDKKRIEAILLKVSVKSEESLYAAVGFGDISPISVFNKLTEKERREEERAKAKA
                     EAEELVKGGEVKHENKDVLKVRSENGVIIQGASGLLMRIAKCCNPVPGDPIDGYITKG
                     RGIAIHRSDCHNIKSQDGYQERLIEVEWDLDNSSKDYQAEIDIYGLNRSGLLNDVLQI
                     LSNSTKSISTVNAQPTKDMKFANIHVSFGIPNLMHLTTVVEKIKAVPDVYSVKRTNG"
     gene            2704..3147
                     /locus_tag="VCR92_000770"
     CDS             2704..3147
                     /locus_tag="VCR92_000770"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEP4267855.1"
                     /translation="MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAY
                     AVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDLA
                     SQLYDSFNEQLAEFVPVERGVFGADMQVSLINDGPVTIILDTKCH"
     gene            complement(3245..4567)
                     /gene="ska"
                     /locus_tag="VCR92_000771"
     CDS             complement(3245..4567)
                     /gene="ska"
                     /locus_tag="VCR92_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023611186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptokinase"
                     /protein_id="HEP4267856.1"
                     /translation="MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLDRPSVNNSQL
                     VVSVAGTVEGTNQEISLKFFEIDLTSQPAHGGKTEQGLSPKSKPFATNSSAMPHKLEK
                     ADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQE
                     FLLSGHVRVRPYQPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGD
                     SLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQ
                     AYGINKKSGQEEKMNNTDLISEKYYILKKGEKPYDPFDRSHLKLFTINYVDVNTNKLL
                     KSEQLLTASEHNLDFRDLYDPRDKAKLLYNNLDAFGIMDYTLTGKVEDNHNDTNRIIT
                     VYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRYTGTPIPDNPNDK"
     gene            4906..5754
                     /locus_tag="VCR92_000772"
     CDS             4906..5754
                     /locus_tag="VCR92_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEP4267857.1"
                     /translation="MELKDYFPEMQVGPHPLGDKEWVSVKEGDQYVHFPKSCLSEKER
                     LLLEVGLGQCEVLQPLGSPWQRYLLDHQGNPPQLFETSQFIYLNHQQALPDDLVELLQ
                     QMIAGLEVILPISATQTAFLCRQAISIKVLRWLEDLLPTLESDFGLALTMFVGNAWYQ
                     VAAGTLRECFEEECQLLTAYLRQQSGRKLLTFSGLMLWSLLSHHTFLALTRQFHQSLS
                     PQSDMADVVHALWSEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLHLKQLDDLAFAH
                     LFLLKY"
     gene            6052..7185
                     /gene="ugpC"
                     /locus_tag="VCR92_000773"
     CDS             6052..7185
                     /gene="ugpC"
                     /locus_tag="VCR92_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEP4267858.1"
                     /translation="MVELNLNHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIGGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAQILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVEVKDGRIVSEDGLAIAIPEG
                     QAKMLEAAGYKGKKVTFGIRPEDISSRQIVHDTYPSATVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHSPGEQVSLTFNVAKGHFFDRDTEQAIR"
     gene            7314..8927
                     /locus_tag="VCR92_000774"
     CDS             7314..8927
                     /locus_tag="VCR92_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEP4267859.1"
                     /translation="MKKHWWHKATIYQIYPRSFKDTSGNGIGDLKGITSQLDYLQKLG
                     ITAIWLSPVYQSPMDDNGYDISDYEAIADVFGDMADMDELLAAANERGIKIIMDLVVN
                     HTSDEHAWFVEARENPNSPERDFYIWRDEPNDLTSIFSGSAWEYDNASGQYYLHLFSK
                     RQPDLNWENEALRHKIYDMMNFWIAKGIGGFRMDVIDLIGKVPDSEITGNGPRLHDYL
                     KEMNQATFGNHDVMTVGETWGATPEIARQYSRPENKELSMVFQFEHVGLQHKPDAPKW
                     DYAEELDVPALKTIFSKWQTELKLGEGWNSLFWNNHDLPRVLSIWGNDSTYREKSAKA
                     LAILLHLMRGTPYIYQGEEIGMTNYPFKDLTEVNDIESLNYAKEAMGNGVSAARVMDS
                     IRKVGRDNARTPMQWSKDTHAGFSEAKETWLPVNPNYQDINVADALADPDSIFYTYQK
                     LIALRKEQDWLVEADYHLLPTADKVFAYQRQLGEETYVIVVNVSDEEQVFAKDLTGAQ
                     VIITNTDVDTVFETKHLQPWDAFCLKLKA"
     gene            9125..12622
                     /locus_tag="VCR92_000775"
     CDS             9125..12622
                     /locus_tag="VCR92_000775"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEP4267860.1"
                     /translation="MKKKVNQGSKRYQYLLKKWGIGFVIAATGTVVLGCTPSILTHQV
                     AAKTIVGLARDEAQQGDGNAKSGDGLQSSSKEAKPVLDSSLANPASIAEHHLRMHFKT
                     LPAGESLGSLGLWVWGDVDQPSKDWPNGAITMTKAKKDDYGYYLDVPLAAKHRQQVSY
                     LINNKAGENLSKDQHISLLTPKMNEVWIDENYHAHAYRPLKKGYLRINYHNQSGHYDN
                     LAVWTFKDVKTPTTDWPNGLDLSHKGPYGAYVDVPLKEGANEIGFLILDKSKTGDAIK
                     VQPKDYLFKELDNHTQIFVKDTDPKVYNNPYYIDQVSLKGAEQTTPNEIKAIFTTLDG
                     LDEDAVKQNIKITDKAGKTVAIDELTLDRDKSVMTLKGDFKAQGAVYTVTFGEVSQVA
                     RQSWQLKDKLYAYDGELGATLAKDGSVDLALWSPSADTVKVVVYDKQDQTRVVGQADL
                     TKSDKGVWRAHLTSDSIKGISDYTGYYYLYEITRGQEKVMVLDPYAKSLAAWNDATAT
                     DDIKTAKAAFIDPSKLGPTGLDFAKINNFKKREDAIIYEAHVRDFTSDKALEGKLTHP
                     FGTFSAFVEQLDYLKDLGVTHVQLLPVLSYFYANELDKSRSTAYTSSDNNYNWGYDPQ
                     HYFALSGMYSVNPNDPALRIAELKNLVNEIHKRGMGVIFDVVYNHTARTYLFEDLEPN
                     YYHFMNADGTARESFGGGRLGTTHAMSRRILVDSIAYLTREFKVDGFRFDMMGDHDAA
                     AIEQAFKAAKAINPNTIMIGEGWRTYQGDEGKKEIAADQDWMKATNTVGVFSDDIRNT
                     LKSGFPNEGTAAFITGGAKNLEGLFKTIKAQPSNFEADAPGDVVQYIAAHDNLTLHDV
                     IAKSINKDPKVAEEEIHKRIRLGNTMILTAQGTAFIHSGQEYGRTKQLLNPDYRTKVS
                     DDKVPNKATLIDAVAKYPYFIHDSYDSSDAVNHFDWAKATDSIAHPISNQTKAYTQGL
                     IALRRSTDAFTKATKAEVDRDVTLITQAGQDGIQQEDLIMGYQTVASNGDRYAVFVNA
                     DNKTRKVVLPQAYRYLLGAQVLADAEQAGVTAIAKPKGVQFTKEGLTIDGLTALVLKV
                     SSKTANPSQQKSQTDNHQTKTPDGSKDLDKSLMTRPKRAKTNQKLPKTGEASSKGLLA
                     AGVALLLLAISLLMKRQKD"
     gene            12737..13111
                     /locus_tag="VCR92_000776"
     CDS             12737..13111
                     /locus_tag="VCR92_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HEP4267861.1"
                     /translation="MRPKEKETSMTFEEIVANFIPSSVAEVTSAIASGKDMIVFLGRS
                     SCPYCRRFAPKLAQVATDNQKEVYFVDSENAADAAELAAFRENYQLVTVPALLVSYDQ
                     HQRAVCDSSLTPDDILAFLTRE"
     gene            13227..13592
                     /gene="yajC"
                     /locus_tag="VCR92_000777"
     CDS             13227..13592
                     /gene="yajC"
                     /locus_tag="VCR92_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEP4267862.1"
                     /translation="MGFPTILMFVVMLGLIWFMQRQQKKQAQERQNQLNAIEKGDEVV
                     TIGGMFAIVDEVDTTAKKIVLDVDGVFLTFELSAIKRIVTKATTETTLVETEETSVVN
                     EPAVETVDSTDTDSAIESH"
     gene            13811..14560
                     /locus_tag="VCR92_000778"
     CDS             13811..14560
                     /locus_tag="VCR92_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEP4267863.1"
                     /translation="MFGLKAKSTKKVLGSIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTITASELGVKVLTVYAFSTENWSRPQDEVSFIMNLPVTFFDKYVPVLHEN
                     NVKIQMIGETSRLPEDTLAALNAAIDKTKRNTGLILNFALNYGGRAEITSAVRFIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFLPWQSAYSEFY
                     FTPVLWPDFKKAELLKAIADYNRRQRRFGKV"
     gene            14573..15367
                     /locus_tag="VCR92_000779"
     CDS             14573..15367
                     /locus_tag="VCR92_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002275264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEP4267864.1"
                     /translation="MKERVVWGGVAVAIFLPFLIIGNLPFQLFVGVLAMIGVSELLKM
                     KRLEVFSFEGVFAMLAAFVLAVPMDHYLTFLPIDANVAFYSLMVFFILAGTVLNSRAY
                     SFDDAAFPIATSFYVGIGFQHLINARLSGIDKVFLALFIVWATDIGAYLIGRQFGRRK
                     LLPTVSPNKTIEGSLGGIACAVLVSFIFMVIDRSVYAPHHFLTMLVLVALFSIFAQFG
                     DLVESALKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            15440..16699
                     /gene="rseP"
                     /locus_tag="VCR92_000780"
     CDS             15440..16699
                     /gene="rseP"
                     /locus_tag="VCR92_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEP4267865.1"
                     /translation="MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FSHVDQGGTLYTLRMLPLGGYVRMAGWGDDKTEIKTGTPASLTLNEQGFVKRINLSQS
                     KLDPTSLPMHVTGYDLEDQLSITGLVLDETKTYKVAHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILLVFLQGGMSDFSSNHVRVQENGAAAKAGL
                     RDNDQIVAINGYKVTSWNDLTEAVDLATRDLGPSQTIKVTYKSHQRLKTVAVKPQKHA
                     KTYTIGVKASLKTGFKDKLLGGLELAWSGAFTILNALKGLITGFSLNKLGGPVAMYDM
                     SNQAAQNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNIIEAIRRKPIKQETEA
                     YITLAGVAIMVVLMIAVTWNDIMRVFF"
     gene            16897..18753
                     /locus_tag="VCR92_000781"
     CDS             16897..18753
                     /locus_tag="VCR92_000781"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEP4267866.1"
                     /translation="MKQSKLLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LANRTIEKFKTIMREEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDNS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHHNYEDLDVTYEDYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAVTPART
                     DLDRWVVLDKSIASMDDIPKEVLEDIKAELAAWMISGEDTIAYSTESSYAANLEMATN
                     EYKPSSKVAAEDALAEVETPHCKTIDEVAAFLSVDETQTIKTLLFVADNEPVVALLVG
                     NDHINTVKLKNYLAADFLEPASEEEARAFFGAGFGSLGPVNLAQGSRIVADRKVQNLT
                     NAVAGANKDGFHVTGVNPGRDFQAEYVDIREVKEGEMSPDGHGVLQFARGIEVGHIFK
                     LGTRYSDSMGATILDENGRTVPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQVAQDLTAKLEADLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTVGKKAAEGIVEIKIKATGDSIEVNAENLIETLEILTKEH"
     gene            19007..23404
                     /locus_tag="VCR92_000782"
     CDS             19007..23404
                     /locus_tag="VCR92_000782"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEP4267867.1"
                     /translation="MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFH
                     FAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAP
                     CNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNSHLPNLVKQFEAFGFGTLTID
                     MVSDQEMTEHLTKDFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKER
                     AAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     ALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHDRKDLM
                     PEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQDAKPLVTVLKAFQDFCKDSIL
                     VAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSL
                     DHHHMANYDAEATGRLLFIFLRDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRANKPVLAT
                     GNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFA
                     FLGKDLAYQVVVENTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAS
                     WQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTE
                     ILGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGY
                     IDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGAS
                     STLVEKMDEMGILGNMPEDNQLSLFDDFF"
     gene            23514..23942
                     /locus_tag="VCR92_000783"
     CDS             23514..23942
                     /locus_tag="VCR92_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEP4267868.1"
                     /translation="MSHLDKNTALKAMVVFRKAQRTLDAFGADIFKKADLTATQFSVL
                     EVLYTKGCMRINHLIDSLLATSGNMTVVLNNMERNGWISKCKDKTDKRAYVVTLTDKG
                     TRLIEAVLPKHVARVEEAFAVLTEKEQLCLIELLKKFKQL"
     gene            24073..24615
                     /locus_tag="VCR92_000784"
     CDS             24073..24615
                     /locus_tag="VCR92_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEP4267869.1"
                     /translation="MKHILFIVGSLREGSFNHQLAAQAQKALEHQAVVSYLNWKDVPV
                     LNQDIEANVPLPVVDARQAVQSADAIWIFTPVYNFSIPGSVKNLLDWLSRALDLSDPT
                     GPSAIGGKVVTVSSVANGGHDQVFDQFKALLPFIRTSVAGEFTKATVNPDAWGTGRLE
                     ISKETKANLLSQAEALLAAI"
     gene            complement(24648..25262)
                     /locus_tag="VCR92_000785"
     CDS             complement(24648..25262)
                     /locus_tag="VCR92_000785"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEP4267870.1"
                     /translation="MSAQDKLIKPSHLITMDDIIREGNPTLRAVAKEVSLPLCDEDIL
                     LGEKMMQFLKHSQDPVMAEKLGLRAGVGLAAPQIDVSKRIIAVLVPNLPDKEGNPPKE
                     AYSWQEVLYNPKIVSHSVQDAALSDGEGCLSVDRVVEGYVVRHARVTVDYYDKEGQQH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFETKEELLILD"
     gene            complement(25388..25645)
                     /locus_tag="VCR92_000786"
     CDS             complement(25388..25645)
                     /locus_tag="VCR92_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEP4267871.1"
                     /translation="MTQNVCQQNITYTVKERFASYTLEAQANQEVHLNLTLLANRFGT
                     SDRHLKHVLKQPIFQRIIERICFKTCRIADLDALTQLSVNN"
     gene            25771..25926
                     /locus_tag="VCR92_000787"
     CDS             25771..25926
                     /locus_tag="VCR92_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267872.1"
                     /translation="MTMLGYRLSAEVRGSAILPLLAGYLIRQAIAQVYSDLKTASWLF
                     GLASSVA"
     gene            26084..26353
                     /gene="rpsO"
                     /locus_tag="VCR92_000788"
     CDS             26084..26353
                     /gene="rpsO"
                     /locus_tag="VCR92_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEP4267873.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNSHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
     gene            26706..28766
                     /locus_tag="VCR92_000789"
     CDS             26706..28766
                     /locus_tag="VCR92_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEP4267874.1"
                     /translation="MLSHELIRNYQLFSKYKGHSLEAFESILKTSKRHILADIAKIND
                     TLSLYQLPLIALDRQLVYPPDLTEKDLLNRMLPTLDDYLFQDERLDMIIIYIMMAKEF
                     ISINHLESLLRLSRNSVIADLNLVRDRVQAFQVTLAYNRQDGYFFEGEPLALRRLLES
                     AVSSLLQVTSGPWVFSYLLHELGLPDQTKVMAATLEELSRENHLTFISEKLRDLIYFF
                     CLLAHRPFSRNVRAEVVDTFPLASPAVETMVDQLLVNFPSLTEEKYLVQSRLLGCIQG
                     DLELVFQQPIYDIMEEIINSVAVNTGLSITDTPELRQNLYSHLLPAYYRLYYDINLTN
                     PLKEQIKQDYESLFYLVKRSLSPLEKQLGKPVNEDEIAYFTIHFGRWLQAPKKRPSNQ
                     LVALSVCPNGISSSLMLEATLKELFPQLQFIRIHQLDKIKLLDPASFDLIFSTVAFDC
                     VKPVYVTQALMGPVEKMMLKKMVCDDFHLPLSEQFALDDLLSIIHKHTTITNKEGLVS
                     DLSRYLFGNHLTIEKGGLGLLDLLTADFIRQADAVSDWQEAIRLAAQPLLEHQMIETS
                     YIDGMIDSVNELGAYIVLAPKVAVPHAAPEKGTRQLGMSLLQLKEPVSFDLKQEGDPD
                     KQVQLIFVLSAVDSSSHLKALQELSLILDDDEHIEQLIEAKNTEEIMSLISHMIEKGD
                     ESHD"
     gene            28759..29043
                     /locus_tag="VCR92_000790"
     CDS             28759..29043
                     /locus_tag="VCR92_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEP4267875.1"
                     /translation="MIKIVTVCGNGIGSSLLLRMKVEAIASSLGIDVDAESCDSNAAV
                     GKGADLFVTVKEFKDIFPEDAKVCIVKSYTNRKKIEEDLVPVLKEMSGKE"
     gene            29070..30449
                     /locus_tag="VCR92_000791"
     CDS             29070..30449
                     /locus_tag="VCR92_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEP4267876.1"
                     /translation="MEALLSFIRDILKEPAFLMGLIAFAGLVALKTPAHKVLTGTLGP
                     ILGYLMLAAGAGVIVTNLDPLAKLIEHGFSITGVVPNNEAVTSVAQKILGVETMSILV
                     VGLLLNLAFARFTRFKYIFLTGHHSFFMACLLSAVLGAVDFKGSLLIILGGFLLGAWS
                     AISPAIGQQYTLKVTDGDEIAMGHFGSLGYYLSAWVGSKVGKDSKDTEDLQISEKWSF
                     LRNTTISTGLIMVLFYLVATVASVLRNTSVTEELAAGQNPFIFAIKSGLTFAVGVAIV
                     YAGVRMILADLIPAFQGIANKLIPNAIPAVDCAVFFPYAPTAVIIGFASSFVGGLLGM
                     LILGVAGGVLIIPGMVPHFFCGATAGIFGNSTGGRRGAMIGAFANGLLLAFLPAMLLP
                     VLGKLGFSNTTFGDVDFGVLGILLGRLGTSIGQIGIYLVVAVLAIVLVLPNFLSKSQE
                     AINNVSEEI"
     gene            30459..31190
                     /locus_tag="VCR92_000792"
     CDS             30459..31190
                     /locus_tag="VCR92_000792"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HEP4267877.1"
                     /translation="MMTKKLNVKVFSDGAVLETMLKDLQTGLVTGFTTNPSLMKKAGI
                     SSYIGFAKEVLAKITDYPVSFEVFADDLASMEKEAEKIASLGDNVYVKIPVTTSTGES
                     TCPVIQKLSAKGIKLNVTAIFTIEQTQAVVDHLTAGVPAIVSVFAGRIADTGVDPMPI
                     MEEALRICRQKEEVELLWASPRETYNIYQADQLGVDIITCTTDLIAKLPLQGKDLEDY
                     SLETVQMFLKDSTSLGFKILEDDNH"
     gene            31470..33602
                     /gene="pnp"
                     /locus_tag="VCR92_000793"
     CDS             31470..33602
                     /gene="pnp"
                     /locus_tag="VCR92_000793"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEP4267878.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKQANGATVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFNGPIAGVQVGYIDGEFI
                     INPDKEQMEASLLELTVAGSKEAINMVESGAKELSEDIMLEALLKGHQAIQELIAFQE
                     QIVAVVGKEKAEVELLQVDADLQADIVAKYNAQLQKAVQVEEKKAREAATEAVKEMVK
                     AEYEERYAEDENLATIMRDVAEILEQMEHAEVRRLITEDKIRPDGRKIDEIRPLDAVV
                     DFLPKVHGSGLFTRGQTQALSILTLAPMGETQIIDGLAPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALEQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTREGITAL
                     QMDIKIAGITPQILEEALAQAKKARFEILDVIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDDEGNVSIYSSDQAAINRTKEIIAGLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWTRTTNVSDVLEVGEDVDVKVIKI
                     DEKGRVDASMKALIPRPPKPEKKEEKHD"
     gene            33595..34347
                     /locus_tag="VCR92_000794"
     CDS             33595..34347
                     /locus_tag="VCR92_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEP4267879.1"
                     /translation="MTKSNELDIRLRAFINAPDNFLDSVALVNAFHNFPVWAAKEPYV
                     IEVEGVKVTPVFTDKEDMARFKEEQESAQSQYWLERSALAVLEEVITSGAAGLVFNLK
                     KKGDFGNSTIFKSSDMIQFMNHYTTVLNTLMSDDNVAADTMEKVYLVPAFVYPKDNNH
                     YDRLFPTMSTPEGKSYVPAFSNLQSFAKWYNQDDFGGLFRKAEGVILTWTIDDIYQPR
                     NGENELDETFGVAINPFDDQQILVDWSELDKS"
     gene            34356..34937
                     /gene="cysE"
                     /locus_tag="VCR92_000795"
     CDS             34356..34937
                     /gene="cysE"
                     /locus_tag="VCR92_000795"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEP4267880.1"
                     /translation="MGWWKESIAIVKALDPAARNSLEVILTYPGIKALAAHRLSHFLW
                     RHHFKLLARMHSQFWRFWTQIEIHPGAQIAPGVFIDHGAGLVIGETAIVEKGVMLYHG
                     VTLGGTGKDCGKRHPTVRQGALISAHAQVIGPIDIGANAKVGAAAVVLSDVPEDVTVV
                     GVPAKIVRVHGQKDNRQIQSLQKQREVSYQLSK"
     gene            35416..35646
                     /locus_tag="VCR92_000796"
     CDS             35416..35646
                     /locus_tag="VCR92_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267881.1"
                     /translation="MNKIRVGLYVIMSLSILVSSITLVASLIFLLRQDMVKAIIYFIL
                     TLFWLIGLVINIKLLKRWNSISEKDLGYQDDN"
     gene            35674..37017
                     /locus_tag="VCR92_000797"
     CDS             35674..37017
                     /locus_tag="VCR92_000797"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000591125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEP4267882.1"
                     /translation="MIKIYDTMTRSLRKFVPLTENTVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYTGYQVNYISNFTDVDDKIIKAATQAGVSPKELSDRFIAAFIEDTKA
                     LGVKPATQNPRVMDYIAEIISFVESLIEKDFAYEADGDVYFRVEKSEHYAKLANKTLS
                     ELEVGASGRTDAETALKENPLDFALWKSAKAGEVSWDSPWGFGRPGWHIECSVMATEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKTFANYWMHNGFVTVDNEKMSKSLGNF
                     VTVHDMLQTVDGQVLRFFLATQQYRKPINFTEKAIHDAEINLKYLKNTLQQPLTETAD
                     EQELKQFVIAFQDAMDDDFNTANGITVVFDMAKWINSGSYTEPVKSAFEKMLAVFGII
                     FEEEVLEVDIEALIAKRQEARANRDFAIADAIRDQLAAQGIKLLDTKDGVRWLRD"
     gene            37010..37423
                     /locus_tag="VCR92_000798"
     CDS             37010..37423
                     /locus_tag="VCR92_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEP4267883.1"
                     /translation="MINPVDVNLINGIALAFEGDAVYSYYVRRHLIFQGKTKPSQLHR
                     LATRYVSAKAQANLIQAMLEAQLLTEKEEDIYKRGRNTNSHTKAKNADIITYRMSTGF
                     EAIMGYLDMMGQKERLEELIRWCIEYVEKQQLISS"
     gene            37619..38416
                     /locus_tag="VCR92_000799"
     CDS             37619..38416
                     /locus_tag="VCR92_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267884.1"
                     /translation="MTTMQKTVSLLSLALLIGLLGTSGKAISVYAQDQHTDNVIAEST
                     ISQVSVEASIRGTEPYIDATVTTDQPVRQPTQATITLKDASDNTINSWVYTMAAQQRR
                     FTAWFDLTGQKSGDYHVTVTVHTQEKAVTGQSGTVHFDQNKARKTPTNMQQKDTSKAT
                     TNSVDVDTKAQTNQSANQEIDSTSNPFKSATNHRSTSLKRSTKNEKLTPTASNSQKNG
                     SNKTKMLVDKEEVKPTSKRGFPWVLSGLVVSLAAGLFIAIQKVSRRK"
     gene            38463..39209
                     /gene="rlmB"
                     /locus_tag="VCR92_000800"
     CDS             38463..39209
                     /gene="rlmB"
                     /locus_tag="VCR92_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEP4267885.1"
                     /translation="MEDKDTIETNDIVYGVHAVTESLQANTGNKLYIQEDLRGKKVDN
                     IKSLATQKKVAISWTPKKTLSQMTDGAVHQGFVLRVSAFAYTDVDEILEIAEQEANPL
                     ILILDGLTDPHNLGSILRTADATNVCGVIIPKHRSVGVTPVVSKTSTGAVEHIPIARV
                     TNLSQTLDKLKARGFWIFGTDMNGTPSDCWNTNGKLALVIGNEGKGISTNIKKQVDEM
                     ITIPMNGHVQSLNASVAAAILMYEVFRNRR"
     gene            39213..39731
                     /locus_tag="VCR92_000801"
     CDS             39213..39731
                     /locus_tag="VCR92_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEP4267886.1"
                     /translation="MKKRILLVDGYNMIAFWQSTRQLFKINQLDQARNTLLTKLNHYA
                     HFENINIICVFDAQYVPGLRQRYDQYYISVVFTEEDETADSYIERMAAELNTAIHMVE
                     VATSDLNEQWTIFSQGALRVTARELEQRVHTVKADLDKMSRDIDLKTPKLRPFDQGQL
                     IQLKDFMSQLDR"
     gene            39828..40688
                     /locus_tag="VCR92_000802"
     CDS             39828..40688
                     /locus_tag="VCR92_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEP4267887.1"
                     /translation="MTFTIMTDSTADLNQTWAEDHDIVLIGLTILCDGEVYETVGPNR
                     ISSDYLLKKMKAGSHPQTSQINVGEFEKVFREHARNNKALLYLAFSSVLSGTYQSALM
                     ARDLVREDYPDAVIEIVDTLAAAGGEGYLTILAAEARDSGKNLLETKDIVEAVIPRLR
                     TYFLVDDLFHLMRGGRLSKGSAFLGSLASIKPLLWIDEEGKLVPIAKIRGRQKAIKEM
                     VAQVEKDIADSTVIVSYTSDQGSAEKLREELLAHENISDVLMMPLGPVISAHVGPNTL
                     AVFVIGQNSR"
     gene            40824..41522
                     /locus_tag="VCR92_000803"
     CDS             40824..41522
                     /locus_tag="VCR92_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267888.1"
                     /translation="MFDSKQNLAKSQWGFIVITAVMDLVVIVATLLAKTSFQRYLVGG
                     VAVILTSFLILLVWGLKTAKKLQTRLDSKEVLDSKVRDDQKLPRYDERQKQILLKGYT
                     IGFWFMIVAVWLSIFLHRFSERLVSASFLFTLALWGGLAVQTTYCNLNGVSPFVDRRF
                     GKQGILVGMIATGMSLITIGLAVREMMAGQLKMGSFFKAGGSGSLMVLGITLLSMGAS
                     IFYRHYLDAKEADE"
     gene            41519..41725
                     /locus_tag="VCR92_000804"
     CDS             41519..41725
                     /locus_tag="VCR92_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4267889.1"
                     /translation="MKNLKLKAARAGKDLSQQALADLVGVSRQTIAAVEKGDYNPTIN
                     LCIAICRVLDKTLDDLFWEVDDSH"
     gene            41943..42389
                     /gene="rplM"
                     /locus_tag="VCR92_000805"
     CDS             41943..42389
                     /gene="rplM"
                     /locus_tag="VCR92_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEP4267890.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            42410..42802
                     /gene="rpsI"
                     /locus_tag="VCR92_000806"
     CDS             42410..42802
                     /gene="rpsI"
                     /locus_tag="VCR92_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEP4267891.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLIINQPFAVTSTEGSYDVFVNVVGGGYGGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(42935..43084)
                     /locus_tag="VCR92_000807"
     CDS             complement(42935..43084)
                     /locus_tag="VCR92_000807"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267892.1"
                     /translation="MIEIGVDPVNTAKRLGHASSQITLDTYSHATAVGEDKSIKQFAN
                     YLKNN"
     gene            complement(43120..43482)
                     /locus_tag="VCR92_000808"
     CDS             complement(43120..43482)
                     /locus_tag="VCR92_000808"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEP4267893.1"
                     /translation="MAALRKGELCALKWANIDFQSETLSVNKSLGRLDGQAIEKSTKN
                     DFSVRKIKLDSETISILQEWKAISQKEKAQLAVAPLSIESDFIFTYCTREGSIEPLHT
                     DYINNILSKVIKQHSLKK"
     gene            complement(43445..43939)
                     /locus_tag="VCR92_000809"
     CDS             complement(43445..43939)
                     /locus_tag="VCR92_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase family
                     protein"
                     /protein_id="HEP4267894.1"
                     /translation="MYLKASGNLEEFTKPTHKTYSEIFEEWYQAYQDTVEPTTASRTL
                     DLFQLHILPVMGELPINKTSPLDCQNFITDKAKTFKNIKQIKSYTEKIFDFAIKMKLL
                     KHNPMAEIIMPKRKKTRIENYWTVQELQEFLAIVLQKEPYKHYALFRLLAYSGLKERR
                     AMRS"
     gene            complement(44067..44402)
                     /locus_tag="VCR92_000810"
     CDS             complement(44067..44402)
                     /locus_tag="VCR92_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEP4267895.1"
                     /translation="MDYKKYQIIYAPDVLEKLKEIRDYISQNYSSTSGQRKMEQIISD
                     IEKLEVFREVGFDADEKYGSKIIHYHSTKGYTLSKDYIVLYHIEGEENRVVIDYLLPT
                     QSDYIKLFK"
     gene            complement(44392..44628)
                     /locus_tag="VCR92_000811"
     CDS             complement(44392..44628)
                     /locus_tag="VCR92_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267896.1"
                     /translation="MVSEAMTVLNKKNLTLSSALRLFLQNVVVTNEVDLLTEEELEKE
                     KLFKQFQAEINKNIEDVRQGKFYTSEEVRAELGL"
BASE COUNT        13226 a         8459 c        10031 g        13187 t
ORIGIN      
        1 aagaggtaac tccagctcca gaaaaacctg ctgacaaaga agctaaccaa acgccagaac
       61 gccgcaatgg caatatggct aagacacctg tagccaacaa ccacagacgt ctaccagcaa
      121 ctggtgagca agccaaccca ttctttacag cagcagcagt agcagtgatg acaacagctg
      181 gtgtcctagc cgttacaaaa cgcaaagaaa acaactaatc ctctgaattg agagacctta
      241 ctgataagca aacataatag agagagcccc ttggttctct ctatttttgg tcgggagctg
      301 gccgttggta tcatgctcac gcctgagaga tcccaaaaga tatcaaaagc agctcactaa
      361 ccgttttcta agaaaaggtc acactaagcg ctttcttagc agattctgcc ttttgctttt
      421 gtgtgtaaag tgttaaaata gggaaaagaa atgctagatg aggaacgaaa tggcaaaaat
      481 aatgaacgta acaggagaag aagtcattgc cttagcggcc acctatatga ccaagactga
      541 tgtggctttt gtggcaaagg ctttagcata tgcaacagcg gcccatttct accaagtgag
      601 aaagtcaggc gaaccctata tcgtccatcc gattcaggtg gcggggattc tggctgattt
      661 gcatctggat gctgtgacag ttgcctgtgg ctttttacat gatgtcgtag aagatacgga
      721 tattacctta gatgagatcg aagcagactt tggccaagat gctcgtgata tcgttgatgg
      781 tgtcaccaag ttaggtaaag ttgagtacaa atctcatgag gagcaactcg ccgaaaacca
      841 tcgcaaaatg ctgatggcta tgtctaaaga tattcgcgtg attttggtga aattggctga
      901 ccgcctgcat aatatgcgca ccctcaaaca tttgcgcaag gacaaacaag agcgcatttc
      961 gcgcgaaacc atggaaatct atgccccctt ggcgcatcgt ttggggatta gtcgcatcaa
     1021 atgggaacta gaagatttgg cttttcgtta cctcaatgaa accgaatttt acaaaatttc
     1081 ccatatgatg aaagaaaaac gtcgcgagcg tgaagctttg gtagaggcta ttgtcagtaa
     1141 ggtcaaaacc tatacgacac aacaagggtt gtttggagat gtgtatggcc gaccaaaaca
     1201 catttattcg atttatcgga aaatgcggga caaaaagaaa cgtttcgatc agatttttga
     1261 tttgattgct atccgttgtg tcatggaaac gcagagcgat gtttatgcta tggttggcta
     1321 tattcatgag ctttggcgtc ccatgccagg ccgcttcaag gattatattg cagctcctaa
     1381 agctaatggc taccagtcga ttcataccac tgtgtatgga ccaaaaggac ctattgagat
     1441 tcaaatcaga actaaggaca tgcatcaagt ggctgagtac ggggttgctg ctcactgggc
     1501 ttataaaaaa ggcgtgcgtg gtaaggtcaa tcaggctgag caagccgttg gcatgaactg
     1561 gatcaaagag ctggtagaat tgcaagatgc ctcaaatggc gatgcagtgg actttgtgga
     1621 ttcggtcaaa gaagacattt tttctgaacg gatttatgtc tttacaccga caggggccgt
     1681 tcaggagttg ccaaaagaat caggtcctat tgattttgct tatgcgatcc atacgcaaat
     1741 cggtgaaaaa gcaacaggtg ccaaagtcaa tggacgtatg gttcctctca ctgccaagtt
     1801 aaaaacagga gatgtggttg aaatcatcac caatgccaat tcctttggcc ctagtcgaga
     1861 ctgggtaaaa ctggtcaaaa ccaataaggc tcgcaacaaa attcgtcagt tctttaaaaa
     1921 tcaagacaag gaattgtcag tgaataaagg ccgtgatttg ttggtgtctt attttcaaga
     1981 gcagggctat gttgccaata aataccttga caaaaaacgc attgaagcga tccttctaaa
     2041 agtcagtgtg aagagcgaag aatcactcta tgcagccgtt gggtttggtg acattagtcc
     2101 tatcagtgtc tttaacaagt taaccgaaaa agagcgccgt gaagaagaaa gggccaaggc
     2161 taaagcagaa gctgaagaat tggttaaggg cggtgaggtc aaacacgaaa acaaagatgt
     2221 gctcaaggtt cgcagtgaaa atggggtcat tatccaagga gcatcaggcc tcttgatgcg
     2281 gattgccaag tgttgtaatc ctgtacctgg tgatcctatt gacggctata ttaccaaagg
     2341 gcgtggcatt gcgattcaca gatcggactg tcataacatt aagagtcaag atggctacca
     2401 agaacgcttg attgaggtcg agtgggattt ggacaattcg agtaaagatt atcaggctga
     2461 aattgatatc tatgggctca atcgtagtgg cctgctcaat gatgtgctcc aaattttatc
     2521 aaactcaacc aagagcatat cgacagtcaa tgctcagccg accaaggaca tgaagtttgc
     2581 taatattcac gtgagctttg gcattccaaa tctgatgcat ctgaccactg ttgtcgaaaa
     2641 aatcaaggca gttccagatg tttatagcgt gaagcggacc aatggctaag aaaggataaa
     2701 accatgaaac ttgtcttgca acgggtcaaa gaggcctctg tttctattga tgggaaaatt
     2761 gctggcgcta ttaaccaagg gttgttgttg ttagtaggtg tgggaccaga tgataatgca
     2821 gaagatttgg cttacgctgt gcgaaaaata gtcaacatgc gcattttttc agatgctgat
     2881 ggcaagatga atcagtctat ccaagacatc aagggcagta tcttatctgt gtcgcaattt
     2941 accctttatg ctgacaccaa aaagggaaac cgtcctgcct ttactggtgc tgctaagcca
     3001 gatttggcta gccagttgta tgatagcttt aatgaacaat tggcagagtt tgtgccagtt
     3061 gagcgtggcg tttttggggc agatatgcag gttagtctca tcaatgatgg accagttacg
     3121 attattttag acacgaaatg tcactagtct ctacaactaa gaggttagaa aaaagcaagc
     3181 aactgttgat agcgtgttgc ttgctttttt tgtcagttaa tctcatcgtt ttagaagatc
     3241 gtggttattt gtcgttaggg ttatcaggta taggtgtccc tgtataacgc aggtagctgt
     3301 aaacttctcg ttcttcttcg gtataacgat ctttatcata agctaaatga tagctagcat
     3361 tctctccttc gggtcgcttg cccatataaa cggttatgat acggttggtg tcattgtgat
     3421 tatcctctac ttttccagtt aaggtatagt ccataatacc aaaagcatcg agattgttgt
     3481 agagtagttt agccttatca cgaggatcgt ataaatctct gaagtctaag ttatgttcgc
     3541 tagctgttaa gagctgctcg ctttttagca atttgttggt gttgacatca acgtaattga
     3601 tggtgaacag tttcaagtga ctgcgatcaa agggatcata cggcttttcc ccttttttaa
     3661 ggatgtaata tttctcagag ataaggtcag tgttgttcat tttttcttcc tgaccagatt
     3721 ttttattgat cccataagct tgttcccggt ctttgatatg gtaagtaaac tcttgatcca
     3781 ttggtaaaat cgtacggaaa atgtcattgt catgagtgac gattgaggag tcacgttttg
     3841 taatgatata atctggatgt ttttttgata ggataaattg ggcaattgct gctaactctt
     3901 gtgatgaaag agagtcacca actgccagtg tggtcaaatg gtattgctct tttaacgatg
     3961 gcgtaaagtc taaatttcct gtttcggaga caaagctcac ttcatagttg acgttaacgc
     4021 gttcagctga gttgtgaacg gctttaggtt gatacggtct aacgcgcaca tgcccgctta
     4081 gcaaaaattc ttggacaggt tgggtcggca aggttaccga atcatctcgg tcagcaaagt
     4141 agaccttgcc gtttcgatca gtaatggttg catcgcttgc aaaatcaatg acctcaaagt
     4201 agccgtcgtt actgtgaacg ttagcgatca attgttcttg aatagccttt aataagtcag
     4261 ctttttcaag tttatgtggc attgcgctac tatttgtagc aaatggtttt gattttggac
     4321 ttaagccttg ctctgtcttt cctccatgag caggttgtga tgttaggtca atttcaaaaa
     4381 atttaaggct aatttcttga ttcgtcccct caacagtacc agcaacgcta acaactaatt
     4441 ggctgttgtt gacagatgga cggtctagca gccattcagg tccagcaata gcttggacag
     4501 gcttgactgt tccaaatgtt aatgcaaaca gcagtgcaaa catcccaaaa gataagtaat
     4561 ttttcataga aacctcctaa aagttaagtt tcaatcccca ttattagaat aacataataa
     4621 ttttatagat acaaacaaaa acctaataat tgtttttaaa tgatatctta atgataacgt
     4681 catgataatg aaaaaagaga ataatacctg ttttagtata aacataaatt aatcttccga
     4741 taaatagcta tttgattgaa tgttcttgct aaaaatgaat aacacttatt tagctttaat
     4801 gattaaaaag acagaaaata caaaatcgtg ctgacaacaa accgaactgt gtgataaaga
     4861 gtcatgtgtt ataatggttt aaagaccatc atgaaaggaa tggctatgga gctaaaagac
     4921 tattttccag agatgcaagt aggccctcat ccgttaggag ataaagagtg ggtgagtgtc
     4981 aaagaagggg accaatatgt gcattttccc aaatcatgtt tatccgaaaa agagcgctta
     5041 ttacttgagg tggggctggg tcagtgtgag gtcttgcagc cgctagggtc accttggcag
     5101 cggtatttgc ttgatcatca gggcaatccc cctcagctgt ttgagacttc tcagttcatt
     5161 tacctcaatc atcagcaggc tttaccagat gacttagttg agttgctcca acagatgatt
     5221 gcagggcttg aggtcatttt gcctatcagt gcaactcaga cggcattttt atgccgacaa
     5281 gcaatctcaa taaaggtctt gcgctggctt gaagatctcc tgccaacgct agaaagtgat
     5341 tttggtttgg ccttaaccat gtttgttgga aatgcctggt atcaagtagc tgcgggtaca
     5401 ttgagagagt gttttgagga ggaatgtcag ctgttaacgg cctatttaag gcaacaatca
     5461 ggcagaaaat tattaacatt ttcaggactg atgctgtggt ctttgctgtc gcaccacact
     5521 tttttggcat tgacgcgtca gtttcaccaa tccctaagtc ctcaaagtga tatggccgat
     5581 gtggttcacg cgctatggtc agaacacggc aatctggtgc agacagcgca gcgcttgtat
     5641 attcaccgta actccttgca atacaaactt gataaatttg ctcagcaatc aggactccac
     5701 ttgaagcaat tggatgattt agcctttgct catctctttt tgttgaaata ttaggaaagc
     5761 cacagagctt tcttttttgc tgcctggact gtagctgata aggagaatga tagatcgttc
     5821 agcttgtttt ggctcctgtg accggcctgt gtttacatag ttttcttggt ttatggtccc
     5881 ttacgacttg actagccctg ctattgtgca agttgcccaa agaagtttgg tcgctttgtc
     5941 tctgttttga aagcgctatt tttgttataa taaaagcatc atataaaaga tatcagcggt
     6001 ttctagcttt gcagtcagct agaacatttg ctggctaaat aggagttata catggttgaa
     6061 ttaaatctaa atcacatcta taaaaaatac ccaaatacta ctcattatgc cgttgaagat
     6121 tttgacttgg acattaaaga caaagaattt atcgtctttg ttggaccttc aggatgtggt
     6181 aaatcaacca ctcttcgtat gattgcaggt cttgaggaca tttctgaagg agagttaaaa
     6241 atcggtggcg aagtggtgaa tgacaagtct cctaaagacc gtgatattgc catggtcttt
     6301 caaaactacg ccctttaccc acacatgacc gtgtatgata acatggcctt tggtttgaaa
     6361 ttacgtaagt acaaaaaaga tgatattgac cgtcgtgtca aggaagctgc gcagattctt
     6421 ggtttgaccg aatttttaga gcgtaaacct gctgacctgt ctggtggtca acgtcagcgt
     6481 gtggctatgg gacgtgctat tgtccgtgat gctaaagtgt tcttgatgga cgagcctttg
     6541 tcaaacttgg atgcgaagct tcgtgtctcc atgcgtgctg aaattgctaa aattcaccgt
     6601 cgtatcggct caacaactat ttacgttacc catgaccaga cagaagccat gactttggca
     6661 gatcgtatcg ttatcatgag tgccactaaa aaccctcaag gtaatggaac gattggtaaa
     6721 attgagcaag tgggttcacc acaagaattg tataaccttc cagctaataa attcgttgcc
     6781 ggttttatcg gaagccctgc catgaacttc tttgaagtgg aagttaaaga tggccgcatt
     6841 gtgagtgaag atggtcttgc tattgcgatt cctgaaggtc aagcaaaaat gcttgaagcg
     6901 gctggttaca aggggaaaaa agtcactttt ggtattcgtc cagaagacat ttctagtaga
     6961 caaatcgtgc atgatactta tccaagtgca actgtcacag cagaagtttt ggtttctgag
     7021 ttactgggct ctgagacgat gctctatgtc aagcttggac aaactgagtt tgcttctcgt
     7081 gtagatgcgc gtgatttcca tagtccaggg gagcaagtta gcttgacctt taatgtggct
     7141 aaagggcatt tctttgacag agataccgaa caagctattc gttaaggtgt aagcgatatt
     7201 cataaaaagg ttgggttcca acctttttat catgtcattt gcgcaaacga ttgcacaaaa
     7261 agagaaaaaa cgttaaaata aaagatgaat gaatgattaa taggagaaga ataatgaaga
     7321 aacactggtg gcataaagct acgatttatc agatttaccc gagatccttt aaagacacca
     7381 gcggcaatgg tattggtgat ttaaaaggca ttaccagtca actggactac ttgcaaaaac
     7441 ttggcattac agccatttgg ttatctcctg tttaccaaag tccaatggat gacaatggtt
     7501 atgacatctc tgactatgaa gcgattgctg atgtttttgg agacatggca gatatggatg
     7561 agctcttagc agcagctaat gagcgaggca ttaagattat catggacttg gtggtcaacc
     7621 atacgtctga tgagcatgct tggtttgttg aagctaggga aaaccctaat agtcctgagc
     7681 gtgattttta tatttggcga gatgaaccta acgatttgac ttctattttt agtggctcag
     7741 cttgggaata tgataatgca tcaggccaat attatttgca cctttttagc aaacgtcagc
     7801 cagatctcaa ctgggagaat gaagctttac gtcataaaat ttacgatatg atgaatttct
     7861 ggattgctaa aggcatcggt ggttttcgta tggacgtgat tgacctgatt gggaaggttc
     7921 cagattctga aatcacgggt aacgggccgc gcttacacga ttacctcaaa gaaatgaatc
     7981 aagcaacctt tggcaatcat gacgtgatga ctgtcggtga gacttgggga gcaacgcctg
     8041 aaattgctcg ccagtattct cgccctgaaa acaaagagtt atccatggtc ttccaatttg
     8101 agcatgtggg tcttcaacat aaacctgacg ctcccaagtg ggattatgcg gaagaactgg
     8161 atgttcctgc tcttaaaact attttcagca agtggcagac agaattaaag ttgggagaag
     8221 gctggaattc gcttttttgg aataaccatg acttgccacg ggtcttatcc atttggggca
     8281 atgacagcac ttaccgagaa aaatcagcca aggctttagc tattttactg catttgatgc
     8341 gaggaacccc ttacatttac caaggagaag agattggcat gaccaattat ccttttaaag
     8401 acttaaccga ggttaatgat attgagtccc ttaactatgc taaggaagct atgggaaatg
     8461 gagtgtcagc tgcgcgtgtg atggatagca tccgtaaggt aggacgagac aatgctagaa
     8521 cgccgatgca gtggtctaag gacacacatg ctggcttttc tgaagcaaaa gagacttggt
     8581 tgccggtcaa ccccaactac caagacatca atgtggccga tgcccttgct gatccagact
     8641 ctatttttta cacctaccaa aaattgattg ccttgcgtaa ggagcaggac tggctagttg
     8701 aagcggatta tcacctcttg ccaacagctg ataaagtgtt tgcttatcag cgtcagcttg
     8761 gagaagagac gtatgtgatt gttgtcaatg tgtctgatga ggagcaagtc tttgccaaag
     8821 acttaacagg tgcacaagtg atcatcacca atacagatgt ggacacggtg ttcgagacca
     8881 agcacttaca accttgggat gccttttgtc tcaaactgaa ggcctagcag ttgtatgtga
     8941 tttgagttta cccaacagcc aagcgagtgg aaactcgttt tggctgtttg atttttgaga
     9001 tcctattaag gggtgatagt cattgtttga gctgtgttct aagttgaagt gcggcatgtc
     9061 ttgcaagcgc ttgcgcaatg tgataagata gtcttgtttg aatgttatac taaatggagg
     9121 tcttatgaaa aagaaagtca accaaggatc aaagcgctat caatatctgt taaaaaagtg
     9181 ggggataggt tttgtaatcg ctgcaactgg gactgtcgtg ttagggtgca cccctagtat
     9241 cttaacacat caagttgctg ctaaaaccat tgttggacta gcccgcgatg aagctcaaca
     9301 aggagatggc aatgctaaat ctggtgatgg tcttcaatcg tctagcaagg aggcaaaacc
     9361 agttttagac agctcgttag ctaatcctgc tagtattgct gagcatcatt tgcgtatgca
     9421 ttttaaaaca ttgccagctg gtgagtcgct aggaagcttg ggactttggg tgtggggaga
     9481 tgtggatcaa ccttcaaagg attggccaaa tggtgctatc accatgacaa aagcgaaaaa
     9541 agatgactat ggctattatc tagatgtgcc actagcagct aaacaccgcc agcaagtgtc
     9601 ttatctcatt aataataaag ctggagagaa tctttcaaag gaccagcaca tctcgcttct
     9661 cacaccaaaa atgaatgaag tttggataga cgagaattac catgcgcacg cttatcgacc
     9721 tttgaaaaaa ggttaccttc gaatcaacta ccacaatcaa tcgggacact acgataactt
     9781 agctgtctgg acctttaaag atgtcaaaac cccaacgacc gactggccaa atggacttga
     9841 cttgtcacat aaagggcctt atggagctta tgttgatgtc cccttaaaag aaggagctaa
     9901 cgaaatcgga tttttaatcc ttgataaaag taagacagga gatgctatta aagtgcaacc
     9961 aaaagattat ctgtttaaag agttagacaa tcatactcag atttttgtca aagacactga
    10021 cccaaaagtc tacaacaatc cttattatat tgatcaggtt agtctcaaag gagctgaaca
    10081 aaccacgcca aatgagatta aagccatttt tacgacctta gatgggcttg atgaagatgc
    10141 ggtgaaacaa aacatcaaga tcactgacaa agcagggaaa actgttgcaa ttgatgagtt
    10201 gacacttgac agggataagt ctgtaatgac attaaagggt gattttaagg cgcaaggtgc
    10261 agtctacacg gttacatttg gagaagttag ccaagtcgct cgccaatcct ggcaattaaa
    10321 agataaactc tatgcttacg atggtgaact tggagctacc ctagctaagg atggttctgt
    10381 tgatttagcg ctatggtctc caagtgctga tactgttaag gttgtcgttt atgataaaca
    10441 agatcagaca agggtggttg gtcaagctga tttgaccaag tcggacaagg gtgtttggag
    10501 agctcatctg acttctgata gtatcaaggg cattagtgat tacacaggct actattacct
    10561 ttatgaaatc acgcgcggtc aggaaaaagt catggttttg gatccttacg ccaaatctct
    10621 cgctgcctgg aatgatgcga ctgctactga tgacatcaaa acagcaaaag ctgcctttat
    10681 tgatccaagc aaactaggac caacaggcct tgattttgcc aaaattaaca actttaaaaa
    10741 gcgtgaagac gctattatct atgaagcaca tgtgcgagat tttacgtcag ataaggctct
    10801 agaaggcaag ttaacacacc cttttgggac tttttcagct ttcgttgaac agctagacta
    10861 tctcaaagac ttgggggtta cccacgttca attgctaccg gttttgagtt atttttatgc
    10921 caatgagctg gacaagagcc gctcaacagc ctacacgtct tcagacaata attacaactg
    10981 gggttatgac ccacaacact actttgccct ttctggcatg tattcggtaa atcctaacga
    11041 ccctgcttta cgtatcgcag agcttaaaaa ccttgtcaat gagattcaca aacgtggtat
    11101 gggtgttatt tttgatgtgg tttataacca cacggctaga acctatctct ttgaagattt
    11161 ggaacccaac tactatcatt ttatgaatgc tgatggcaca gctagagaga gttttggcgg
    11221 aggtcgtcta ggaacgacac atgccatgag tcgtcgtatc ttggtggatt cgattgctta
    11281 tctgactcgt gaattcaagg tagatggttt tcgtttcgac atgatgggtg accatgatgc
    11341 ggcagctatt gagcaagcct ttaaggcagc caaagccatt aatccaaata ccattatgat
    11401 tggcgaaggc tggcgtacct accaaggtga tgaggggaaa aaagaaattg cggcagatca
    11461 agattggatg aaagcaacca atacggtcgg tgttttctct gatgatatca gaaataccct
    11521 caagtcaggt ttcccaaatg aaggcacagc agcctttatt actggtggcg caaaaaatct
    11581 agaaggactg ttcaaaacga tcaaagcaca gcctagtaac tttgaagcag atgccccagg
    11641 agatgtagtg cagtatattg cagcccatga caacctgacc ttacatgatg tcattgccaa
    11701 atccatcaat aaggatccta aagtggctga agaagagatt cataagcgta ttcgtctagg
    11761 aaataccatg attttaactg ctcaagggac tgcctttatc cattctggtc aggaatatgg
    11821 acgaaccaag cagcttctaa atcccgacta caggacaaag gtgtctgatg acaaggtgcc
    11881 aaataaggcg actctgattg atgctgtagc gaaataccct tacttcatcc acgattctta
    11941 tgattcgtct gatgcggtca atcattttga ctgggcaaag gcaacagatt ccatagctca
    12001 cccgattagc aaccaaacaa aagcctatac acagggccta attgcgttgc gtcgctcaac
    12061 agatgccttt acaaaagcaa ccaaagctga ggtagatcgg gatgtgacct tgatcaccca
    12121 agcaggacaa gatggtattc aacaagagga ccttatcatg ggttaccaaa cggtggcatc
    12181 aaatggagat cgctatgctg tctttgtcaa tgcagacaac aagacccgca aggtagtttt
    12241 acctcaagcc taccgctatt tgctaggagc ccaagtgctt gctgatgctg agcaggctgg
    12301 tgttactgcc attgctaagc ctaagggagt ccagtttacc aaagaaggct tgactattga
    12361 tggcctaact gccctggtcc tcaaagtatc ctcaaaaaca gctaatccct ctcagcaaaa
    12421 gagtcagaca gacaatcatc aaaccaaaac accagatggc tcaaaagacc tagataaatc
    12481 attaatgact aggccaaaaa gagctaaaac aaaccaaaag ctcccaaaaa cgggtgaagc
    12541 ctcctcaaaa ggcttattag cagctggagt agctctgctt ttattggcta ttagcctgtt
    12601 gatgaagcgc caaaaagatt agggtggtgt taatagagac aaaaagattg ctgtttgcgg
    12661 attctttttg acggctataa aagctctgag ctgtgaaaag accttgtgat tgagaaaatt
    12721 gctactttag tgtatcatga gaccaaaaga gaaggagaca tccatgacat ttgaagaaat
    12781 cgttgcgaat tttataccgt cgagtgttgc agaagtcaca tcagctattg ctagtggcaa
    12841 agacatgatt gtctttttag gacgttcgag ctgtccttat tgtcgccgct ttgctcctaa
    12901 gttggcacaa gtggcaacag ataatcaaaa agaagtctat tttgtggata gtgaaaacgc
    12961 tgctgatgct gctgagcttg ctgcctttcg tgagaactac caattagtga cagttccggc
    13021 tttgctggtt agttacgatc agcaccaaag ggctgtatgt gattcaagtt tgacaccaga
    13081 tgacatctta gcttttttga ctcgtgagta aaggactgcg cttagcgtct cgtttaaaga
    13141 agaaatcagg taacgtctag tcttgctata cctcttgatt tttgatatag taagacatga
    13201 cttttataga ataaaaagga gacattatgg gatttccaac aattttaatg tttgtagtga
    13261 tgcttggatt gatttggttt atgcaacgtc aacaaaaaaa acaagcgcaa gaacgccaaa
    13321 accagttaaa cgctattgaa aaaggagacg aagtcgtaac gattggtggc atgtttgcga
    13381 ttgttgacga agtcgataca acagctaaaa agattgtgtt agatgtggat ggcgtctttt
    13441 tgacatttga gctatcagct attaagcgta ttgtaacaaa agctaccaca gaaacgacac
    13501 tggttgaaac agaagaaacc agtgttgtta atgagcctgc tgttgagaca gtagatagca
    13561 ctgacactga cagtgccatt gaaagccatt aaggcgggga aagtttggat gaaatatgcc
    13621 aaactttttt gttttgatcc ctggactgaa acagttattc tgatgctaac aggttcatga
    13681 aaagctgaca catctatcag aggataggtg aacattttgt gaagataaga tctaattgat
    13741 aaaaaacaag ccaaaaggcg tgaaatatga taaaatatga gataagtatg cttatcaata
    13801 aggaaaaaac atgtttggat taaaagcgaa atcaacaaaa aaagttttgg ggagtatccc
    13861 aaagcatatt ggaattatca tggatggtaa tggacgttgg gccaaaaaaa gactaaaacc
    13921 tagagtgttt gggcataaag ctgggatgga tgctttacaa gaagtaacga ttactgcatc
    13981 tgagttgggg gttaaagttc tgacagtcta tgccttttcg acagaaaact ggtccagacc
    14041 ccaagatgag gtgtctttta tcatgaattt accagtaacc ttctttgaca aatatgtgcc
    14101 tgtgcttcat gagaacaatg taaagattca aatgattgga gagactagtc gtttacctga
    14161 agataccttg gcagcgctaa atgcagccat cgacaaaaca aaacgtaata cgggtttaat
    14221 tttgaatttt gctctcaatt atggaggacg tgctgagatt accagtgctg ttcgctttat
    14281 tgctcaagat gtcttagatg ccaaattaaa tccaggagat attacggagg atttgattgc
    14341 taattacttg atgacagacc atctgccata tctctaccga gaccccgatt tgattattcg
    14401 caccagtggt gagctgcgtt tgagcaattt cttgccttgg caatcagctt acagtgaatt
    14461 ttatttcaca ccagtcttgt ggcctgattt taaaaaggca gagctactaa aggccattgc
    14521 ggattataac cgccgccaac gtcgttttgg caaggtctaa aaggagatag ttatgaaaga
    14581 acgtgttgtt tgggggggag tagcagtagc tattttccta ccttttctca taataggaaa
    14641 cctaccattc caattatttg taggcgtttt ggccatgatt ggggtatcag aattactgaa
    14701 aatgaaaaga ttagaagtct tttcttttga aggtgttttt gccatgttag ccgcctttgt
    14761 attggcagtt ccgatggacc attacctcac ttttttacca attgatgcga atgttgcttt
    14821 ttacagctta atggtttttt tcattttggc aggtactgtt ttaaatagca gagcttattc
    14881 atttgatgat gcggcctttc cgattgcaac tagtttttat gttgggattg gttttcaaca
    14941 tttgatcaat gctcgcctgt caggaattga caaggtcttt ttggccttat ttatcgtttg
    15001 ggccactgat attggagcat atctgattgg gcgtcagttt ggtaggcgca aactattgcc
    15061 tacagtttct ccaaacaaaa ccattgaagg tagtttagga gggatcgctt gtgcagtcct
    15121 tgtgtctttt atctttatgg tgattgatag gtctgtttat gcgccacatc actttttgac
    15181 catgttggtt ttggtcgctc ttttttccat ttttgcccaa tttggtgatt tggttgaaag
    15241 tgctctcaaa cgtcactttg gtgtcaaaga ttcaggtaag cttatcccgg gacatggtgg
    15301 tattttagac cgctttgatt ccatgatttt tgtttttccc atcatgcatc tctttggttt
    15361 attttaatct taagaggtaa tgtttggagt cgcaacaacg cgacaaaact caaaaaagca
    15421 atagactgaa aggaaatcta tgttaggaat aataaccttt attattattt ttggtatttt
    15481 agtgattgtc catgaatttg gacatttcta ttttgctaaa aaatcaggca ttctagtaag
    15541 agaatttgcc attggaatgg gccctaaaat tttttctcat gttgaccaag gaggaactct
    15601 ttataccttg aggatgttac ccttgggtgg ttatgtgcga atggctggtt ggggtgatga
    15661 caaaactgag atcaaaacag gtactccagc aagtttaacc cttaatgagc aaggttttgt
    15721 taagcgcatc aacttgtctc aaagtaagtt agacccaacg agtctcccaa tgcatgttac
    15781 aggctatgac ttagaagatc agctgagtat tactggcttg gttttagatg aaaccaagac
    15841 atataaggtc gctcacgatg ctactattgt tgaagaagac ggtactgaga taagaattgc
    15901 tccgcttgat gttcaatatc aaaatgctag tattggcgga cgtttaatca ccaattttgc
    15961 aggtcccatg aataatttta ttttagggat tgtggttttt atcctcttgg tctttttaca
    16021 aggtgggatg tcagatttta gtagcaatca tgtccgtgtt caagaaaatg gagcagcagc
    16081 taaggctggt cttcgagata atgaccaaat tgtcgcaatt aatggttata aggtgactag
    16141 ctggaatgat ctcactgagg ctgtagacct tgcaacacgg gatctaggcc cgtcacagac
    16201 cattaaggtc acctacaagt cacatcagcg cttaaaaacg gtggctgtga aaccacaaaa
    16261 gcatgcaaag acatacacga taggagttaa ggcgagtctg aaaacaggat ttaaggataa
    16321 gctcttaggc ggtctagaat tagcttggag tggggcgttt actattttga atgctttgaa
    16381 aggattgatc actggcttta gtctcaataa attaggtgga cctgttgcca tgtatgacat
    16441 gtccaatcag gctgctcaaa acggcttaga gtcagtctta tctcttatgg caatgctttc
    16501 gatcaattta gggatcttta acctgattcc gattcctgca cttgatgggg gaaaaatctt
    16561 gatgaatatc attgaagcca ttcgtcgcaa gcctatcaag caagaaacag aggcctatat
    16621 caccctagct ggggttgcta tcatggtcgt attgatgatt gctgtgacat ggaatgatat
    16681 catgcgcgtc tttttctaat caagataggt catcttaagc tgaccttatc atgttaaaga
    16741 tcgaaaaaga cctcaaccct aagatttgca agggttgagg tcttactcaa aatgaaagga
    16801 atacacattc aaattattga ataatcccgc ttcactctta cttgatgttt ccagaagggt
    16861 ttgaggataa ggggatgtat taaaacggaa taatctatga aacaaagtaa actgcttatc
    16921 ccaaccttgc gcgaaatgcc aagtgatgcc caggttatca gccacgcgct tatggtgcgt
    16981 gccggttatg tgcgccaagt ttctgctggt atctatgctt atttaccact ggcaaatcgt
    17041 accattgaga aattcaagac catcatgcgt gaagagtttg aaaagatcgg tgctgttgaa
    17101 atgttggcac cagctctttt gacagctgat ctctggcgtg aatcaggccg ttatgagacc
    17161 tatggagagg acctctataa gcttaaaaac cgtgataact cagactttat cttgggtccg
    17221 acccacgaag aaacctttac gactttggtg cgtgatgcgg tcaaatctta caagcaattg
    17281 cccttaaacc tttatcaaat tcagtctaag tatcgtgatg aaaaacgtcc gcgtaatggc
    17341 ttgcttcgta cccgtgagtt tatcatgaaa gacggctata gtttccatca caactatgaa
    17401 gatttagatg tgacctacga agattatcgt caagcttacg aagctatttt taccagagct
    17461 ggtctagatt tcaaagggat tattggagat ggcggtgcca tgggggggaa agattcccaa
    17521 gaatttatgg ccgttacacc agctcgtacg gaccttgatc gctgggtggt tcttgacaag
    17581 tctattgcgt caatggatga tataccaaaa gaggtcttag aagatattaa ggcagaattg
    17641 gctgcttgga tgatttcagg tgaagatact attgcttatt caacagaatc aagctacgct
    17701 gccaaccttg agatggcaac taacgaatac aaaccgtcct caaaagtagc tgctgaagat
    17761 gccttggcag aagttgagac accacattgc aaaacgattg atgaagtggc tgcttttctt
    17821 tcagtagatg aaacacaaac catcaaaacc ttgctttttg tggcagataa tgaacctgtt
    17881 gttgctttgc tagttggaaa tgaccatatc aataccgtta aattaaaaaa ctatctagct
    17941 gctgattttt tagagccagc tagtgaagaa gaagcccgtg ctttctttgg tgcaggtttt
    18001 ggctcacttg ggcctgtcaa cttggcacaa ggtagtcgca ttgtggctga ccgcaaagtg
    18061 caaaacctta ccaatgccgt tgcaggagct aacaaggatg gtttccatgt gacaggagtc
    18121 aatccaggac gtgacttcca ggctgaatat gtagatattc gtgaagtcaa agaaggggaa
    18181 atgtctccgg atggtcatgg tgttctccag tttgcacgtg gtatcgaagt cggtcatatc
    18241 ttcaagttgg gcactcgtta ttcagacagc atgggagcaa cgattcttga tgaaaatggc
    18301 agaacagttc caattgtgat gggttgttat ggtatcgggg ttagccgcat tttgtctgct
    18361 gtcattgaac agcatgcccg tctctttgtg aacaagacac caaaaggcga ttaccgttat
    18421 gcttggggta ttaacttccc taaagaatta gccccatttg acgtgcattt gattacagtt
    18481 aatgtcaaag atcaagtggc ccaagacttg acggcgaagt tagaagctga cttgatggct
    18541 aaagggtatg atgtcttgac agatgaccgt aatgaacgcg tcggttcaaa attctctgat
    18601 agcgatttga ttggtttgcc aattcgtgtc actgttggta aaaaagccgc tgaaggtatc
    18661 gtggaaatta aaatcaaggc aacaggtgac agcattgaag ttaatgcaga aaacctcatc
    18721 gaaacccttg aaattttaac aaaagaacac taaaaaagaa atgaagaggc tgcctgttta
    18781 gagtggcctc tttttgctgt gaacttgtct gatacagagt ggcttttgct ttaccaaaag
    18841 cgcttggcga caaaagattg gcaaaaaaat gacctcagct gagctatcac ttggaataaa
    18901 ttagccaaag aacgtcagaa gaaagccctg cttttctttc catctaaaac tcgaaaatca
    18961 tcttgaattg tgataaaata aagcctagta aaatcaggag aaaattatgt cagatttatt
    19021 cgctaaattg atggaccaga tagaaatgcc acttgacatg agacgttcaa gtgccttttc
    19081 atctgctgat attatcgagg taaaggtgca ttcggtgtca cgcttgtggg aatttcattt
    19141 tgcctttgcg gcggttttac cgattgcaac ttatcgtgaa ttacatgatc gtttgataag
    19201 aacttttgag gcggctgaca ttaaggtaac ctttgatatc caagctgctc aggtggatta
    19261 ttcagatgat ctgcttcaag cttattacca agaagctttt gagcatgcac cgtgtaatag
    19321 tgctagtttt aaatcttctt tctcaaagct caaagtgact tatgaggatg acaaactcat
    19381 tattgcagcg ccaggttttg tgaataacga tcattttaga aacagtcatc tgcctaatct
    19441 ggtcaagcaa tttgaagcct ttggctttgg caccttgacc atagatatgg tgtcagatca
    19501 ggagatgact gagcatttga ccaaggattt tgtttccagt cgtcaggctc ttgtgaaaaa
    19561 ggctgtgcag gataatttgg aagcccaaaa atcccttgaa gccatgatgc caccagttga
    19621 ggaagccaca cctgctccta agtttgacta caaggaacga gcagctaagc gtcaggcagg
    19681 gtttgaaaaa gcgaccatca caccaatgat tgagattgag accgaagaaa accggattgt
    19741 ctttgagggt atggtttttg atgtggagcg taaaacgact agaacaggtc gccatatcat
    19801 caactttaaa atgacagact atacctcctc gtttgctctg caaaaatggg ccaaagacga
    19861 tgaggagctc cgtaaatttg acatgattgc taagggagct tggttacggg tacaagggaa
    19921 tattgagacc aatcctttta cgaagagtct caccatgaat gtgcagcagg tcaaagaaat
    19981 tgtccatcat gaccgcaaag acctgatgcc agaagggcaa aagcgggtcg aacttcatgc
    20041 ccacaccaat atgtctacca tggacgcctt accgacagta gaaagcttga ttgatacggc
    20101 agccaagtgg ggacacaagg cggttgctat taccgaccat gctaatgtgc aaagttttcc
    20161 tcatggctac catagggctc gcaaagctgg aattaaggct atttttggcc tagaagccaa
    20221 tattgttgag gacaaggtgc ctatttctta tgatcctgtt gatatggatt tgcacgaagc
    20281 tacctatgtg gtctttgacg tggaaaccac aggtctatct gctatgaata atgacctgat
    20341 tcagattgcg gcttccaaaa tgtttaaagg caatattgta gagcagtttg atgaattcat
    20401 tgatcctggg catcctcttt ctgcctttac caccgaattg acagggatta ccgataagca
    20461 tttgcaggac gccaagccat tggttaccgt cctaaaagct tttcaggact tttgcaaaga
    20521 tagtatcttg gttgcccaca acgccagttt tgacgtgggc tttatgaacg ccaattatga
    20581 acgccacgac ttgcccaaaa tcacacagcc tgtgattgat accttagaat ttgctagaaa
    20641 cttgtatcct gagtacaagc gtcacggttt gggaccgctc accaagcgtt tccaagtgag
    20701 tctagaccac catcatatgg ccaattacga cgcggaagcc acaggacgtc ttttgtttat
    20761 ttttctaaga gatgccagag aaaagcatgg catcaaaaat cttttgcaac tcaatacaga
    20821 tttggtagct gaggattctt acaaaaaagc gcggattaag catgcgacta tctatgtgca
    20881 aaatcaggtt ggccttaaaa atatgtttaa gttggtcagc ctttccaata ttaaatattt
    20941 tgaaggggtg ccgcgtattc caagaaccgt cttagatgct cacagagagg gtttgttact
    21001 tggtacagct tgttctgacg gcgaggtttt tgatgccgtt ctgactaaag gaattgatgc
    21061 ggcggttgat ttggctaagt attatgattt tatcgaaatc atgccaccag ccatttacca
    21121 gccattggtt gtccgtgaat taatcaaaga ccaagcaggt attgagcagg tgattcgtga
    21181 cctcattgaa gtagggaaac gagctaataa acctgtactt gccactggaa atgtgcatta
    21241 cctagagcct gaagaagaga tttaccgtga aattattgtg cgtagtctcg gtcagggtgc
    21301 catgattaat agaacaatcg gccgtgggga aggggcccaa cctgctcccc tacctaaagc
    21361 gcactttaga acaaccaatg aaatgctgga tgagtttgcc tttcttggaa aagacctcgc
    21421 ttatcaagtg gttgtagaaa atactcagga ttttgcggac cgtattgagg aagtggaagt
    21481 ggttaagggc gatctttaca ccccgtatat tgacaaggcc gaagagacgg ttgccgaatt
    21541 aacctatcaa aaagcctttg aaatttatgg taatcctctc ccagatatta ttgatttacg
    21601 cattgaaaaa gagttaacct ctatcttggg gaacggtttt gctgtgattt atctcgcttc
    21661 ccaaatgctt gttaaccggt caaatgagcg aggctatctg gttggctcta ggggatctgt
    21721 agggtctagc tttgtcgcca ccatgattgg gattactgag gttaatccta tgccgcctca
    21781 ctacgtttgc ccgtcctgcc aacattctga atttatcaca gatgggtcag ttggatctgg
    21841 ctatgatttg cctaataaac cctgtccgaa atgtggcacc ccttatcaaa aagatgggca
    21901 agacattccc tttgagacct ttcttgggtt tgatggggat aaggtgcccg atattgattt
    21961 gaacttctct ggtgatgacc agcccagtgc ccatttggat gtccgagata tttttggtga
    22021 cgaatacgcc tttcgtgctg gaacagttgg taccgtagca gaaaaaacag cttatggatt
    22081 tgtcaaaggc tatgaacgcg actatggcaa gttctatcgt gatgctgagg tggatcgtct
    22141 agcagcaggt gctgctggtg tgaaacgaac gactgggcag caccctgggg ggattgttgt
    22201 tattcctaat tacatggatg tttatgattt tacccccgtg caatatccag cagatgatgt
    22261 aacggcttct tggcagacaa ctcactttaa cttccatgat attgatgaaa acgtcttgaa
    22321 acttgatatc ctagggcatg atgatccgac catgattcgt aaacttcagg atttatcggg
    22381 cattgatcct attactatcc ctgctgatga tccaggtgtt atggctctct tttctgggac
    22441 agagattttg ggcgttaccc cggaacaaat tgggacaccg actggtatgc taggcattcc
    22501 agaatttgga accaactttg ttcgcggcat ggttaatgag acgcatccga ccacttttgc
    22561 ggagcttttg cagttgtctg gactatctca tggaaccgat gtttggcttg gtaatgcaca
    22621 agatttgatt aaagaaggca ttgcgaccct aaaaaccgtt atcggttgtc gtgacgacat
    22681 catggtttac ctcatgcacg caggcttaga accgaaaatg gcctttacca ttatggagcg
    22741 tgtgcgtaag ggcctctggc tgaaaatttc tgaggaagaa cgtaatggct atattgatgc
    22801 catgcgagaa aacaatgtgc ccgactggta cattgaatcg tgtggaaaaa tcaagtacat
    22861 gttccctaaa gcccatgcgg cggcctatgt cttgatggcc cttcgggtgg cttatttcaa
    22921 ggtgcaccac cccattatgt attattgtgc ttatttctct attcgtgcga aggcttttga
    22981 attaaaaacc atgagtggtg gcttagatgc tgttaaagca agaatggaag atattactat
    23041 aaaacgtaaa aataatgaag ccaccaatgt ggaaaatgac ctctttacaa ccttggagat
    23101 tgtcaacgaa atgttagaac gcggctttaa gtttggcaaa ttagaccttt acaaaagtga
    23161 tgctatagaa ttccaaatca aaggagatac ccttatccct ccatttatag cgttagaagg
    23221 tctgggtgaa aacgtggcca agcaaatcgt taaagctcgt caagaaggcg aattcctctc
    23281 taaaatggaa ttgcgtaaac gaggcggggc atcgtcaacg ctcgttgaga aaatggatga
    23341 gatgggtatt ttaggaaata tgccagaaga taatcaatta agtctttttg atgacttttt
    23401 ctagattatc atgatggtag tcatatgcaa agtcataaaa gaagagggac aagatcactt
    23461 tctaatctct ctgatactaa attgtgacat accgtataaa gcgaggaaat caaatgagtc
    23521 atttagataa gaacaccgct ttgaaagcca tggtggtgtt tcgtaaagct cagcgaacgc
    23581 tagatgcttt tggggctgat atttttaaaa aggcagattt aacagccacg cagttcagtg
    23641 tgcttgaagt actatatact aaaggctgta tgcgaatcaa tcacttgatt gattctttgt
    23701 tagcgacttc ggggaatatg actgttgtac taaataatat ggaacgtaat ggctggatta
    23761 gcaagtgcaa agacaaaacg gataaaagag cctatgtggt taccttaaca gataagggta
    23821 ctcgcttgat tgaagctgtt ttgcctaaac acgtcgcacg ggtggaagaa gcctttgctg
    23881 ttttgactga aaaagaacaa ctttgtctga ttgaacttct caaaaagttc aaacaattat
    23941 aaacaaatct ctttacagct cttcttagag aagatataat tactacatag tgataaattt
    24001 caaaaagaag tatcaatgaa ataccacttt tagaaagctt taaaacgatc tttaaaaaaa
    24061 gaggacaaag agatgaaaca tattttattt attgttggct cgcttcgtga agggtctttt
    24121 aaccatcaat tagcggctca agcacaaaaa gctctggaac atcaagcagt agtatcttac
    24181 ttaaattgga aagacgttcc tgttttgaat caagatatcg aagctaatgt acctttacca
    24241 gttgttgacg ctcgtcaagc tgttcagtca gcggatgcta tctggatttt tacaccagtt
    24301 tacaacttct ctattccagg ttctgttaaa aacctgctag actggttgtc tcgtgctctt
    24361 gatttgtctg atccgacggg cccatctgct attggcggta aggtggttac ggtctcttca
    24421 gttgcaaatg gcgggcatga tcaagtattt gatcagttta aagcactatt gccgtttatc
    24481 cgaacttcag tagcaggaga gtttacaaaa gcaactgtga atcctgatgc ctggggaaca
    24541 ggaaggcttg agatttcaaa agagacaaaa gcaaacttgc tatctcaggc agaggctctt
    24601 ttagcggcta tttagactaa caaaaaaagg ctaaagggcc ttttttgtta gtctaaaatc
    24661 aagagctctt ctttggtttc aaaggggttt ttagcattga tccgatcgta gaacaaaaca
    24721 ccattgatat ggtcaatttc atgttgaacc acaatagcgt tgtatccctt taatttgatg
    24781 cgatgctgtt gtccttcttt atcatagtag tctactgtaa cacgagcatg gcgaaccaca
    24841 tacccttcaa caacacgatc gacagataaa caaccttcgc catcagaaag ggctgcatct
    24901 tgaacagaat gagaaacgat tttaggatta tacaggactt cttgccagct ataggcttct
    24961 ttaggaggat ttccttcttt atcaggaaga ttaggaacga gcacagcgat gatacgtttt
    25021 gacacatcaa tctgaggagc tgctagacca acaccggccc taagtccaag tttttccgcc
    25081 attacaggat cttgagaatg cttcaaaaat tgcatcatct tttctcctaa taggatatcc
    25141 tcatcacaca agggtaagct cacttctttg gcgacagctc ttaaagttgg attcccttca
    25201 cgaataatgt catccatggt aatcagatga ctaggtttaa ttaatttatc ttgtgcagac
    25261 atgtctactc ctttactttt ttttaactgg atttactata tcacaaatca tttctttttt
    25321 aaagaaaagt caggtagtgg tcagagtgat tgctattata agttaatggg ctgcatacct
    25381 cagaggtcta gttattaaca cttaattgag ttagagcgtc taaatcggca atacgacagg
    25441 ttttgaagca gatgcgttcg ataatcctct gaaaaatggg ctgcttaagt acgtgcttaa
    25501 gatggcgatc gcttgttcca aaacggtttg ctaataatgt aaggtttaga tgaacctctt
    25561 ggttggcttg cgcttcaagg gtataggaag caaagcgctc tttgacggta taggtaatgt
    25621 tttgttggca aacattttgt gtcaactctt gacctatgtc ataaaggcag gtcgcatcgg
    25681 ttaataagct gtgttcatgg attagggatt gggtttgtta atactagagc aattaatatt
    25741 atcagtgaac actttgttgg aaagaaatga atgactatgc taggttaccg cttatcagct
    25801 gaagtgcggg gatcagccat cttacctctt ttagctggtt atcttattag gcaagcaatc
    25861 gcacaggttt attctgattt aaaaacagcc tcttggctat ttggccttgc tagttctgtt
    25921 gcttaaggtg gtttggatgt gagagcttag aataatagga taacggttga cctaatatta
    25981 tgaatctgct agaatagagt ggtcgaaaga caaaccaact ttttcttggt tttaggagtg
    26041 ccaatcctaa gactcggatt aagcaaaaaa aggagaatat attatggcaa tctcaaaaga
    26101 gaaaaaaaat gaaatcattg ctcaatatgc acgtcacgaa ggcgatactg gttcagttga
    26161 agttcaagta gcagttctta catgggaaat caaccacttg aacagccaca tcaaagaaca
    26221 caaaaaagac cacgctactt accgtggatt gatgaaaaaa attggtcacc gtcgtaactt
    26281 gttggcatac ctacgtcgta cagatgttaa ccgttaccgt gagttgatcc aatctcttgg
    26341 acttcgccgt taatttcaag tttaaaaagt cctctgctta tgcagtgggc tttttcattt
    26401 ttgacatgtt gtttgttaac ttacacattt ggctagaatg gtctaagact gtttttttaa
    26461 gcagttgatg attttattta acaacaaaag gtatctcagt gatgaggtat cttttgttgt
    26521 atcatgaaga aaaagggaat caattcccag atttgcctat ttttggccac cttttgagga
    26581 acttgttaca atgatatcac ctgttgagtc caattgcagt caaaaatgac tacggacaat
    26641 tggactcaat ttgtcttgaa aatgaaaacg cttcatttta tactgacatt ataggaggag
    26701 atgacatgct atctcatgag ctcatcagaa actatcaact cttttctaaa tataaaggac
    26761 attcactgga ggcatttgaa tccatattaa agacaagcaa acgtcatata ctggcagata
    26821 ttgctaaaat caatgacacg ttgtcactct atcagttacc ccttattgct ctggacaggc
    26881 agctggttta tccgccagac cttactgaaa aggacttgtt gaatcgcatg ctacctacct
    26941 tagacgacta tctctttcaa gatgagcgtc tggacatgat tatcatttac atcatgatgg
    27001 ctaaagaatt tatctccatt aaccacttgg aaagcttgtt acggctcagc agaaattccg
    27061 ttattgctga tttaaacttg gtgcgtgatc gggtacaagc ttttcaggta actttagctt
    27121 acaatcgcca ggatggttat ttttttgaag gagaaccctt agccttgcgg cgtctcttag
    27181 aatcagcggt cagttctctt ttgcaagtta catcaggacc ttgggtgttc agttacttat
    27241 tgcatgaact tggtttgccc gaccagacaa aggtgatggc agcaacgttg gaggaactga
    27301 gcagggagaa ccacttaact tttatttcgg agaaattgag ggatttgatt tattttttct
    27361 gccttctcgc tcatcgacca ttttcacgga acgtaagggc tgaagtagtg gatacttttc
    27421 ctttagcttc gccagctgtt gaaacgatgg tggaccagtt attggtcaac ttccccagtc
    27481 taaccgaaga gaaatatttg gttcaatcta ggttacttgg ttgtatccaa ggtgacttag
    27541 agttagtctt tcagcaacct atttatgaca ttatggagga aatcatcaat tcggtggcgg
    27601 ttaacacggg attgtctatc accgataccc cagaacttcg tcagaaccta tacagtcacc
    27661 ttttgccagc ttattaccga ctttactacg acattaactt gaccaatcct ttgaaggaac
    27721 aaatcaaaca agattatgaa tctctctttt acttggtcaa gcgcagcctt tctcctctag
    27781 aaaaacaatt ggggaaacca gttaatgaag atgagattgc ttattttacc attcattttg
    27841 ggagatggtt gcaggcccct aagaagaggc cgagcaatca gctggtagcc ttatctgttt
    27901 gccctaatgg catcagttcg tctctgatgt tggaggcaac cttgaaggaa ctttttccac
    27961 agctacagtt tattaggatt caccagctgg acaaaataaa gttgttggat ccagcttcct
    28021 ttgatttgat tttttcaaca gtagcttttg actgtgttaa acctgtttat gtgacgcaag
    28081 ctttgatggg acctgttgaa aaaatgatgt tgaaaaagat ggtctgtgat gactttcatc
    28141 ttcccttgtc agagcaattc gctttggatg acctgttgag tattattcat aaacacacca
    28201 cgattactaa taaagaagga cttgttagtg atttatcccg ttacctgttt ggtaaccatt
    28261 taacgattga aaaaggaggt ctaggactat tggacttgtt aacagcagat tttattaggc
    28321 aggctgatgc tgtttcggat tggcaggaag cgattcgttt ggctgctcag cctttactag
    28381 aacaccagat gattgaaaca tcttatatcg acggtatgat tgattcggtc aatgagcttg
    28441 gagcctatat tgttttagcc cctaaggtgg ctgttcctca tgcggcgcct gaaaaaggaa
    28501 cgcggcagtt aggcatgtct ctcttacaac taaaagaacc tgtcagcttt gatttgaagc
    28561 aagaaggtga tccagacaag caagtgcaat tgatttttgt tttgtctgct gtggattcta
    28621 gttcacattt gaaggctttg caggaactgt cgttgatttt agatgatgat gaacatattg
    28681 agcaattaat tgaggctaag aatactgagg aaataatgag tctgattagc catatgattg
    28741 aaaaaggaga tgaatcacat gattaaaatt gtaacggttt gtggaaacgg tattggtagt
    28801 agcttgttac ttcgcatgaa agtagaagct atcgcctcta gtttgggtat tgatgtggat
    28861 gcagaatcct gtgattccaa tgcggctgtt ggaaagggtg cagatttgtt tgttaccgtt
    28921 aaagaattta aagatatttt tccagaggat gccaaggttt gtatcgttaa aagctatacc
    28981 aatcgtaaaa aaattgaaga agatttggtt ccggttctca aggaaatgag tggcaaggaa
    29041 taagccttta aaggagatag gaagatacta tggaagcatt attatcattt attcgagata
    29101 ttttaaaaga acctgcattt ttaatgggct tgattgcctt tgcagggttg gtggctttga
    29161 aaacacctgc tcataaggtg ttgacaggaa ccttggggcc gattttggga taccttatgc
    29221 ttgctgcagg ggcgggtgtt attgtgacca atctggaccc tcttgccaaa ctcattgagc
    29281 acggttttag catcactggc gtagtgccaa ataatgaagc cgtcacttct gtcgctcaaa
    29341 agattctggg tgtggaaact atgtccatct tggtggttgg gttattgctt aatttggctt
    29401 ttgctcgttt tacccgcttc aaatacattt tcttaacagg acatcacagc ttctttatgg
    29461 cttgtctctt gtccgccgtg cttggagctg ttgatttcaa aggaagtctt ttgattatct
    29521 taggtgggtt cctcttggga gcttggtcag ctatttcgcc agccattggt caacagtata
    29581 ctctgaaagt gactgacgga gatgaaatcg ccatgggaca ctttggtagt ttgggctatt
    29641 acctttctgc ctgggttggt agcaaggttg gcaaagacag taaagatacc gaggaccttc
    29701 agatttctga aaaatggagt ttcttacgca acaccaccat ttcaacagga cttatcatgg
    29761 tgcttttcta cttggtggca acagtggctt ctgttttgag gaatacttca gtaacagaag
    29821 aattagcagc aggtcaaaac ccatttatct ttgctattaa gagtggtctt acctttgcgg
    29881 ttggtgtggc aattgtctac gccggtgttc gcatgatttt ggctgacttg attccagcct
    29941 tccaaggtat tgctaacaaa ttaattccaa atgctattcc agccgtggat tgtgcggtat
    30001 tcttccctta tgcgccaacc gctgttatca tcggttttgc gtcaagtttc gttggtggct
    30061 tacttgggat gttgatttta ggagttgcag gtggtgtcct gattatccca ggtatggtgc
    30121 ctcatttctt ctgcggtgca acagcaggga tttttggaaa ttcaacaggt ggtcgtcgcg
    30181 gtgcaatgat tggtgctttc gctaatggct tattactcgc cttcttgcca gccatgcttc
    30241 tacctgtact tggtaaactt ggtttttcaa acacgacctt tggagatgtg gatttcggtg
    30301 ttttagggat tttactgggc cgcttaggaa cgtcgattgg tcaaatcggt atttacttgg
    30361 tggttgctgt gcttgctatt gtattggtgc ttccaaactt tctgtcaaaa tctcaagaag
    30421 ccatcaataa tgtttcagaa gaaatctaaa aggaggatat gatgacaaaa aaactaaacg
    30481 ttaaagtctt ttcagacggt gcggtcttag agaccatgtt aaaggattta caaacaggtt
    30541 tggtcacagg ctttacaacc aatccaagtt tgatgaaaaa agcaggcatc agttcttata
    30601 ttggctttgc caaagaagtg cttgccaaaa ttacagacta cccagtgtcc tttgaagtct
    30661 ttgcggatga tctcgcaagc atggaaaagg aagctgagaa aattgccagt ctaggtgaca
    30721 atgtctatgt gaaaattcca gtcaccactt caacaggcga atcaacttgt cccgttattc
    30781 aaaagttgtc agccaaaggc attaagttaa acgtcacagc catttttaca attgagcaga
    30841 ctcaagctgt ggttgatcat ttaaccgctg gagtgccagc tattgtgtct gtttttgctg
    30901 gtcgtattgc agacaccggc gttgacccaa tgccaatcat ggaagaagct ctacgcattt
    30961 gtcgtcaaaa agaagaggtc gaattgttgt gggctagtcc tcgtgaaact tataatatct
    31021 atcaagctga tcagttaggc gtggacatta tcacttgtac cactgatttg attgccaagt
    31081 tgcctcttca aggaaaagat ttagaagact attcccttga aaccgtgcaa atgtttctga
    31141 aagacagtac cagcctcggc tttaaaattt tagaggatga caatcattaa tattaggaga
    31201 cgaaagcagg cataccaacc tgcttttttt gctttgttaa agagtataag tttcgtttaa
    31261 tatttttcaa ggacatttca agagattgcg atctgacagt gaaatttctg ctattttatg
    31321 gtaaaatgta gcagatacgt cgtttgatac aaagaggagc gtgtgacaag cgtggcaggt
    31381 tgctttttgt agcaaaacaa cgtataacaa ctgaatctaa gcagagaaca ggtacctctt
    31441 tacccctctg aaaattaaaa ggagaatata tgtcaaaaca aacctttaca acaacatttg
    31501 cagggaaacc ccttgttgtt gaagttggtc aagtcgctaa gcaagccaac ggggcaaccg
    31561 ttgttcgtta cggagaatca accgtcctga ccgcagctgt tatgtctaag aaaatggcaa
    31621 cgggtgattt cttccccctt caagttaatt acgaagaaaa aatgtatgcc gctggtaaat
    31681 tcccaggagg tttcatgaag cgtgagggac gcccttcaac agatgcgacc ttgacagctc
    31741 gcttgattga ccgcccgatt cgtcccatgt ttgccgaggg ttttcgtaac gaagtacaag
    31801 tgattaacac tgtcctttct tatgatgaaa atgctagcgc tccaatggca gcgatgtttg
    31861 gctcatctct ggccttgtcc atctcagata ttccatttaa tggaccgatt gcaggtgttc
    31921 aagttggcta tattgatggt gagttcatca ttaacccaga taaagaacag atggaagcgt
    31981 cactcttaga attaaccgtt gctggtagca aagaagccat caacatggtt gaatctggtg
    32041 ccaaagaatt atcagaagac atcatgcttg aggctctttt aaaaggtcac caagccattc
    32101 aagaattaat tgccttccaa gaacaaatcg tagcagttgt tggtaaagag aaagctgagg
    32161 ttgaactgtt acaggttgat gcagacttac aagctgatat tgtggctaag tacaatgctc
    32221 aactgcaaaa agctgttcaa gttgaagaga aaaaagcgcg tgaagcagcc acagaagccg
    32281 ttaaagaaat ggttaaggct gagtacgaag agcgttacgc agaagacgaa aacctagcaa
    32341 ccattatgcg tgacgtggca gaaatccttg aacaaatgga gcatgctgaa gtgcgccgcc
    32401 tcattacaga ggacaagatt cgtcctgacg gtcgtaagat tgacgaaatt cgtccgcttg
    32461 atgctgtggt tgacttcttg ccaaaggtcc atggatcagg tctttttacg cgcggtcaaa
    32521 ctcaggcgct atcaattttg accttggcac caatgggaga aactcaaatc attgatggtc
    32581 tggccccaga gtacaaaaaa cgcttcttgc atcactacaa tttcccgcaa tattcagttg
    32641 gtgaaacggg tcgttacgga gctgctggtc gtcgtgaaat tggacacggt gccttaggtg
    32701 aacgcgctct tgaacaagtc ttgccaagct tagaagagtt tccttatgcc attcgtttag
    32761 ttgccgaagt tctagaatct aacggttcgt cttctcaggc ttctatctgt gctggtaccc
    32821 ttgctctgat ggctggtggt gtaccaatca aggctcctgt ggcagggatt gccatgggtc
    32881 tcatttcaga cgggacgaat tatacagtct tgaccgatat ccaaggtctt gaagaccact
    32941 ttggagatat ggactttaaa gtggcaggaa ctcgtgaagg gattacagcc cttcaaatgg
    33001 atattaagat tgcagggatt acgcctcaaa tcctagaaga agctcttgca caagctaaaa
    33061 aagctcgctt tgaaatcctt gatgtgattg aagcaactat cgctgaacca cgtcccgagt
    33121 tagccccaac tgcaccgaaa attgacacca tcaagattga cgtagacaaa atcaaagtgg
    33181 ttatcggtaa aggtggcgaa accattgata agattattgc cgaaacgggt gtcaaaattg
    33241 atattgatga cgaaggaaat gtctctatct actcaagtga ccaagctgcc attaaccgca
    33301 ctaaagaaat catcgctggc ctagtacgtg aagctaaggt aggtgaagtt taccatgcta
    33361 aggttgtccg tattgagaaa tttggtgcct ttgtcaacct ctttgacaag acagatgcac
    33421 ttgttcacat ttctgaaatt gcttggacta gaacgaccaa cgtgtcagat gtccttgaag
    33481 tgggtgaaga cgttgatgtt aaggtcatta agattgatga gaagggtcgt gtggacgcct
    33541 caatgaaagc tttgattcca cgcccaccaa aaccagagaa aaaagaagaa aaacatgact
    33601 aaatcaaatg aattagatat tcgcttaaga gcttttatca atgcgcctga taactttttg
    33661 gatagtgttg cccttgtcaa tgctttccat aattttcctg tctgggctgc taaagaaccc
    33721 tacgtgatag aagtcgaagg tgtcaaggtt acccctgttt ttaccgataa ggaagatatg
    33781 gctcgcttta aagaagaaca agagagtgct caaagtcagt attggctgga gcgttcagct
    33841 cttgcagtgc tagaagaagt cattacatct ggtgcagcag gtcttgtctt taaccttaag
    33901 aaaaagggag attttgggaa ttctaccatt ttcaaaagca gtgatatgat tcaatttatg
    33961 aaccattaca ccactgtgtt aaatacgctt atgagtgatg acaatgtggc ggcagatacg
    34021 atggaaaagg tttaccttgt tcctgccttt gtttatccta aagataataa ccattacgac
    34081 cgcctttttc ctaccatgtc aacgcctgaa ggaaaaagct atgttcccgc cttttcaaat
    34141 cttcaaagct ttgcgaaatg gtacaaccaa gacgattttg gaggcctttt caggaaagct
    34201 gaaggagtga ttctgacttg gacgattgat gatatttatc aaccaagaaa tggtgaaaac
    34261 gagcttgatg aaacgttcgg tgtcgccatc aatccttttg atgaccaaca aattcttgtt
    34321 gattggtcag aattagataa gtcgtaggag ttagtatggg ttggtggaaa gaaagtatag
    34381 ctattgttaa agctctagac ccagctgctc gtaatagtct tgaggttatc ctaacttatc
    34441 caggcatcaa agccctagct gctcatcgtt tgtctcattt tctttggcga catcatttta
    34501 aattactagc cagaatgcat agccaatttt ggcgattttg gacacaaatt gaaatccatc
    34561 ctggagcaca aatcgctcct ggagtcttca ttgaccatgg tgctggtctt gttattggag
    34621 agacagcaat tgttgaaaaa ggtgtgatgc tttatcatgg ggtgacccta ggtggaaccg
    34681 gaaaagattg tggcaagcgt catccaacgg ttcgacaagg tgccttaatt tcggcacatg
    34741 cccaagtgat tggacctatt gacatcggag caaatgctaa agtaggggca gcagctgttg
    34801 tgttatcaga tgttcctgaa gacgtgacag ttgtaggtgt gccagctaag atagtacgag
    34861 tgcatgggca aaaagataat cgtcaaattc aaagtttaca aaaacaacga gaggtctctt
    34921 atcagttgtc aaaatgatcg gaaaataaca aaaagaagca ctgatgactt ccgataaaat
    34981 attttgggac tttctagtag agtaatgttg aacttagcta gccctatcag tttggttgct
    35041 gagtgtagtg atatgggaat gttacaaaat acaaaaaaca cgtaaaagag catcaactaa
    35101 gcaagtctta gactgaagaa acagtctatt gtgatacttt ttctcaggtg gtgcttacgg
    35161 cagcgacttc ctttggaatt ccatgcctta gttttgagcc taaggtctca aaaatctgta
    35221 tgggcatcac tgtcagtatt gataccactt ttaccacaac aaaaagcagc tgttttggct
    35281 caccccacat gcagaaatag gaaacctgat gtcaaatcag cagatctatt catgcttttt
    35341 gagcataaaa gtgggtttgt ctactttctg aagccttcac aggttgtgaa ggtttttcgt
    35401 taataaagga gcctcatgaa taaaataaga gttgggctgt atgtcattat gagtttgtct
    35461 attcttgttt ctagtattac actggtggct agtctaatct ttttactgag acaagacatg
    35521 gttaaagcga ttatatactt cattttgacc ctattttggt taataggttt ggttattaat
    35581 attaaattgt tgaaaaggtg gaatagcatt tcagaaaaag acttaggata tcaagatgac
    35641 aactaatgct aggatattga ataaggagtt tacatgatta aaatttatga taccatgacc
    35701 cgttcgctcc gcaagtttgt acctttgact gaaaatacag tcaatatgta cgtttgtgga
    35761 ccgacggtct ataattatat tcatattgga aatgctagat cagcggtcgc ttttgacacc
    35821 attcgacgtt attttgagta tactggctat caggtcaatt acatttccaa ttttaccgat
    35881 gtcgatgata aaattatcaa ggctgctact caagcaggtg tttctcctaa agaattgtca
    35941 gatcgcttta ttgcagcttt tatagaagat accaaggcac ttggtgttaa gccagccaca
    36001 caaaatcctc gtgttatgga ttatatagca gaaatcattt catttgttga aagcctcatt
    36061 gaaaaagatt ttgcttacga agcagatgga gatgtgtatt tccgcgtgga aaagtcagag
    36121 cattatgcca agctagctaa taaaaccctg tcagaacttg aagttggagc cagtggtcga
    36181 acagatgctg agacagcttt aaaagaaaat ccactggact ttgctctttg gaaatcagct
    36241 aaggcaggtg aggtttcttg ggatagcccc tgggggtttg gtcgtccagg ctggcacatt
    36301 gaatgttctg tgatggctac tgaaattctt ggtgatacca ttgatattca tggtggcgga
    36361 gctgatttgg aatttcctca tcataccaat gaaattgccc aatctgaggc taaaacaggc
    36421 aagacttttg ctaactattg gatgcacaat gggtttgtca ctgttgataa cgaaaaaatg
    36481 tccaagtcac taggtaattt tgtgaccgtt catgacatgt tacaaaccgt tgatggtcag
    36541 gttttgcgat tctttcttgc gacacaacag taccgaaaac caattaactt cactgaaaag
    36601 gctattcatg atgcggaaat caatctgaag tatcttaaaa acaccttgca acaaccgctg
    36661 acagaaactg cagatgagca agagctaaaa cagtttgtaa tagctttcca agacgctatg
    36721 gacgatgatt tcaatacagc aaatgggatt accgtcgtat ttgacatggc taagtggatt
    36781 aattctggct cctatacaga acctgttaaa agcgcttttg agaaaatgtt agctgttttt
    36841 ggcattatct ttgaagaaga ggtgcttgag gttgacattg aagccttgat tgctaagcga
    36901 caagaagcac gcgcgaatcg tgattttgcc atagctgatg ccattcgaga tcagttagca
    36961 gctcaaggca tcaagctgct agataccaaa gatggtgtga ggtggctgcg tgattaatcc
    37021 agttgatgtg aatttgatta atggcattgc cctagccttt gaaggagatg cggtttattc
    37081 ctactatgtt cgtcgtcatc tcatttttca aggtaaaacg aaacctagcc agctacaccg
    37141 tttagcaacg agatatgttt ctgctaaggc acaagccaac ttgattcagg ctatgttaga
    37201 agcgcagcta ttgaccgaaa aagaagaaga catctataag cgtggtcgca ataccaatag
    37261 ccatactaaa gctaagaatg ccgatattat tacctatcgt atgtcaacag gttttgaagc
    37321 cattatgggt tatcttgata tgatgggcca aaaagagcgg ttagaagaat tgatcagatg
    37381 gtgtattgag tatgtagaaa agcaacaatt gatatcctca taagagtccc ctaggagact
    37441 cttattttca taggtctgaa gtaaaggtag agagccatta actcttttta tgacatcaaa
    37501 aagacataat gatataaaaa agatacattt gtaacaaaaa agacataaaa ataatgaaat
    37561 cattttcgaa tagtttataa tgagagggta agactaattt aaagaggaga tatttattat
    37621 gacaactatg caaaaaacag ttagcttatt atcactagct ttacttattg gtttgctggg
    37681 gacttctggc aaagccatat ctgtgtatgc acaagatcag cacactgata atgttatagc
    37741 tgaatcaact attagtcagg tcagtgttga agccagtata cgtggaacag aaccttatat
    37801 tgatgctaca gtcaccacag atcaacctgt cagacaacca actcaggcaa cgataacact
    37861 taaagacgct agtgataata ctattaatag ttgggtatat actatggcag cgcaacagcg
    37921 tcgttttaca gcttggtttg atttaactgg acaaaagagt ggtgactatc atgtaactgt
    37981 caccgttcat actcaagaaa aggcagtaac tggtcaatca ggaactgttc attttgatca
    38041 aaacaaagct agaaaaacac caactaatat gcaacaaaag gatacttcta aagcaacgac
    38101 gaattcggtc gatgtagaca caaaagctca aacaaatcaa tcagctaacc aagaaataga
    38161 ttctacttca aatcctttca aatcagctac taatcatcga tcaacttcct taaagcgatc
    38221 tactaaaaat gagaaactta caccaactgc tagtaatagc caaaaaaacg gtagcaacaa
    38281 gacaaaaatg ctagtggaca aagaggaagt aaaacctact tcaaaaagag gattcccttg
    38341 ggtcttatca ggtctagtag tcagtttagc tgcaggttta tttatagcta ttcaaaaagt
    38401 atctagacga aaataaaaga gtctatgcat ttattttgaa gcattcatgg tataataaac
    38461 tcatggaaga taaagatact attgaaacaa acgatatcgt ctatggtgtt catgccgtta
    38521 cagaaagcct tcaagcaaat acaggaaata agctttatat ccaagaggat ttaagaggaa
    38581 agaaagtgga taacatcaaa agcttagcga cacaaaaaaa ggtcgctatt tcatggacgc
    38641 ctaaaaaaac cttgtcacaa atgactgatg gagctgtgca tcaaggtttt gttctgagag
    38701 tatcagcttt tgcctatact gatgttgatg agatcctcga aatagcagag caagaagcaa
    38761 atcctttgat tcttatttta gatggtctga cagatcctca taatttagga tcgattttac
    38821 ggacagctga tgctacaaat gtatgtggag tgattattcc taaacatcgt tctgttggtg
    38881 tgactccagt ggtctcaaag acgtctacag gtgctgttga acatattccg atagcgagag
    38941 taactaacct tagtcaaact ctagataaat tgaaagcaag aggattctgg atttttggca
    39001 cagacatgaa tggaacaccg tctgattgct ggaacactaa tggtaaactt gctttagtca
    39061 ttggtaacga aggcaaaggc atctctacca atatcaaaaa gcaagttgat gaaatgatta
    39121 cgattcctat gaatggtcac gtacagagct taaatgctag cgtagcggca gctattctca
    39181 tgtatgaagt tttccgaaat aggcgctaaa ttatgaaaaa acggatatta ttagtagatg
    39241 ggtataatat gattgccttt tggcaatcaa cccgtcagtt gtttaagata aatcagcttg
    39301 atcaggcacg taacacactt ttaacaaaac ttaatcatta tgcccatttt gagaatatta
    39361 atattatttg tgtttttgat gcccaatatg taccggggtt aaggcaacga tatgaccagt
    39421 attatatctc agtggtattt acagaggaag acgaaacagc agatagctac attgagcgca
    39481 tggcagcaga gttaaatacg gctatacata tggtagaagt agctacgagt gatttaaatg
    39541 aacaatggac gattttttct caaggagctc ttcgtgtcac tgcaagagaa ttagagcaaa
    39601 gagttcatac tgtcaaagct gatttagata aaatgtctag agatattgat ctcaaaacgc
    39661 ctaaactgcg gccttttgac caaggacagc ttattcaatt gaaggatttt atgtctcagt
    39721 tagatcgata atgagaatta cgactcgcca agtgcgggtt tttttgataa aataaaacaa
    39781 taattatttg attatcaaac taaaaaactg gatgaggaga agtaagaatg acctttacaa
    39841 taatgacaga ttcaaccgct gatttgaatc aaacctgggc agaagatcat gatattgtcc
    39901 ttataggatt aacgattttg tgcgatggag aggtttatga aacggtcggt cctaaccgta
    39961 ttagtagtga ttaccttttg aaaaagatga aagctggcag tcatcctcaa accagtcaga
    40021 ttaatgtggg agagtttgag aaggtttttc gtgaacatgc taggaacaac aaagcactgc
    40081 tttatcttgc tttttcttcg gttttatcgg gtacctatca aagcgctcta atggcacgcg
    40141 atcttgttcg agaagattat cccgatgcag tgattgaaat tgttgatacc ttggctgctg
    40201 caggaggaga aggctatcta accattttag cagcagaagc cagagatagt ggcaaaaatt
    40261 tactggagac taaagatatt gttgaagcag tgattcctcg actgcgcacc tatttcttag
    40321 tagatgatct ttttcatttg atgcgtggtg ggcgtctgtc aaaaggttca gcttttctag
    40381 gcagtttagc cagtatcaaa cctcttttgt ggattgatga ggaagggaaa ttggtgccca
    40441 ttgcaaaaat tcggggacgc caaaaagcca tcaaagaaat ggtggctcaa gtggaaaaag
    40501 atattgcgga ttcgacggtt attgtctctt atacaagcga tcagggtagt gccgaaaagt
    40561 tacgagaaga gctgctggcg catgagaata ttagcgatgt tcttatgatg ccactaggac
    40621 cagttatctc agctcacgtt ggtcctaaca ccctggcagt ttttgtgatt gggcagaatt
    40681 ctcgttaatc ccttataagg attgaagaga aatcctcaat ccttttttgc tgcttaaatc
    40741 aatcaagaat gtaaaatata tttgacaaaa tatccaaaat aatttatatt atgtcatata
    40801 aagatttaaa ggagaaacga atcatgtttg atagcaaaca aaatctcgct aagtcacaat
    40861 ggggtttcat tgtcataaca gcagtgatgg atctagttgt gatagtagca acattactgg
    40921 ctaagaccag ttttcaacgt tacttagttg gaggcgtagc ggttatattg actagctttc
    40981 tcatattgtt ggtatggggg ctaaagacag cgaaaaagct ccaaacgaga ctagatagca
    41041 aagaagtact agattctaag gtaagggacg atcagaagct gcccagatat gacgaacgcc
    41101 aaaaacagat tcttctcaaa ggatacacta ttgggttttg gtttatgatt gtggctgttt
    41161 ggctgtcaat ctttcttcat cgcttctcag agagactggt atctgcaagc ttcctcttta
    41221 cattggctct ttggggaggg ttggcagttc aaacgacata ttgtaacctc aacggggtat
    41281 cgccatttgt ggataggcgc tttggaaaac aaggcatact ggtggggatg atagcaacag
    41341 gaatgagttt aatcactata ggtttggcgg taagagagat gatggcaggg caacttaaaa
    41401 tgggaagctt tttcaaggct ggcggcagtg gatctttaat ggtgttgggc ataacgctcc
    41461 ttagtatggg agctagtatt ttctatcgtc attatctgga tgctaaagag gcagatgaat
    41521 gaagaacctc aaattaaaag cagcgcgtgc aggcaaagat ttgtctcaac aagctctagc
    41581 agatttggta ggcgtctcca gacaaaccat tgcggctgtt gaaaaaggtg attacaaccc
    41641 aacgattaat ctttgcattg ccatttgtcg agtacttgat aagaccttag atgacctttt
    41701 ttgggaggtt gatgattccc attaacatca gcagagcagc tctgccattc ctcaaaaacg
    41761 aaagaaaaaa taatccaata aaatcagcta aagcacttga ctggagcctc ttaagtttga
    41821 tatcatagta ggcggtattg tttaccccat ttgaaaggcc ccggaacctt ccaaatacct
    41881 tcgatgggat ggaacaccca tcaccttgta aacaaatatt acgaattcgt ataggagaaa
    41941 tcatgaacaa aacaactttc atggctaaac caggccaagt tgaacgcaaa tggtacgttg
    42001 ttgacgcaac tgatgtgcca cttggacgtc tttctgcagt agttgctagc gtacttcgcg
    42061 gaaaaaacaa accaactttc acaccacata ctgatacagg tgattttgtt atcgttatca
    42121 acgctgaaaa agttaaatta actggtaaaa aagcgactga taaagtttat tacactcact
    42181 caatgtaccc aggtggtttg aaatcaatca ctgctggtga acttcgctct aaaaacgcag
    42241 ttcgcttgat tgaaaaatca gttaaaggca tgcttccaca taacactctt ggacgtgcac
    42301 aaggtatgaa attgaaagtc ttcgttggcg gtgagcacac tcacgcagca caacaaccag
    42361 aagtacttga catctcagga cttatctaag aggaaaggag cattaaataa tggcacaagc
    42421 acaatatgca ggtactggcc gtcgtaaaaa cgctgttgca cgcgttcgtt tggttccagg
    42481 tactggtaaa atcactgtta acaaaaaaga tgtagaagaa tacatcccac atgctgacct
    42541 acgtttgatc attaaccaac cttttgcagt tacatcaact gaaggttcat acgacgtttt
    42601 cgttaacgtt gttggtggtg gttacggtgg acaatcaggt gcgatccgtc atggtatcgc
    42661 tcgtgcgctt cttcaagtag acccagactt ccgcgattcg ttgaaacgcg ctggccttct
    42721 tacacgtgac gcacgtatgg ttgaacgtaa aaaaccaggt cttaagaaag ctcgtaaagc
    42781 ttcacaattc tcaaaacgtt aagaacagct ttacatcaac gattacaagc attttgcaag
    42841 tctcttgcaa ggtgcttttt ttgtcgtttt ttgcttttga tacctttttt tgataccgtt
    42901 tcggaaaact tttgacttgg tttaatacgt ttatttagtt atttttgaga tagttagcaa
    42961 attgtttgat tgatttgtct tctccgactg cagtagcatg actgtatgta tcaagagtta
    43021 tttgactact agcatgtcct aaccttttgg ctgtatttac tgggtcaact ccaatctcaa
    43081 tcatcagggt tgcatgggta tgcctgaagc cgtgaggact tattttttaa gactatgttg
    43141 cttaatgacc tttgataaga tattgttaat atagtctgta tgaagtggtt caatactccc
    43201 ttctctagta cagtatgtaa atataaagtc agactcaatt gaaagaggtg caactgctag
    43261 ttgtgccttt tctttttggc tgatggcttt ccattcttgc agaatagaaa tagtttcgct
    43321 gtctagctta atctttctta ctgagaaatc atttttagtg cttttttcga ttgcctgtcc
    43381 gtctaatcgt cctaggctct tattgacgct tagtgtctca ctctgaaagt ctatattagc
    43441 ccatttaaga gcgcatagct cgcctttcct taaggccgct ataagctagt agccgaaata
    43501 gtgcgtagtg cttgtaaggc tctttctgaa gtactatggc taaaaactcc tgaagttctt
    43561 gaaccgtcca atagttttct attcgtgtct ttttccgctt tggcataatg atttcagcca
    43621 tagggttatg cttgagcagt ttcatcttga tggcaaaatc aaagatcttt tcagtgtagg
    43681 acttgatttg cttgatattc ttaaaggtct ttgctttatc ggtgatgaag ttctggcagt
    43741 ctaaagggga ggttttgtta atgggcaatt ctcccatgac tggcaaaatg tgaagttgaa
    43801 acagatcaag agtacgagaa gccgtggttg gctctaccgt atcttgatag gcttgatacc
    43861 attcctcgaa tatctcgcta taagttttat gagttggctt ggtgaactcc tctaagtttc
    43921 ctgaagcctt aaggtagatt agcctatctt cgtagtcttt ggcttctttg tggaatatct
    43981 actaaacagc ccgaacttat tttgctccta gttaattggt aatctaccaa aaaagcccta
    44041 gcaagactgc taaggctttt aatgtgttat ttgaataact ttatatagtc gctttgagta
    44101 ggaagcaagt aatcaataac gaccctattt tcttccccct cgatatggta taggacaata
    44161 taatctttac ttaaggtata acctttagtg ctgtgataat ggatgatttt tgaaccatat
    44221 ttttcatcgg catcaaaacc aacttctcgg aaaacctcga gtttttctat gtcgctaatg
    44281 atttgctcca ttttacgctg acctgatgtt gaggaatagt tttgagaaat ataatcacga
    44341 atttctttta gcttctctaa aacatcagga gcatagataa tctgatattt cttatagtcc
    44401 aagttcagcc ctcacttctt cagaggtata aaacttccct tgacgaacat cctcaatatt
    44461 tttgttgatt tcagcttgaa attgcttgaa aagtttttct ttctctaact cctcttccgt
    44521 caataagtca acctcgtttg tgacaacgac attttgtagg aataatctta aagcagatga
    44581 taaggttaaa ttttttttgt ttaatactgt cattgcttcg cttaccaatt ctttattagc
    44641 ttgaaaggta accgctctgt tttttttact gtagtcattt tatgtaaccc ctttatgtaa
    44701 tttatttaat tatatcatat atacaaaaaa gtcaataaaa aagactcggt aattgagaca
    44761 gattttcatt atttgataag ctccgaaact tatttttgat accgtttagg tttaaatatt
    44821 tgtctataaa taagattttt agtgattttt cattttagaa acattgattt taaagggatt
    44881 tgactttaaa taatggagtg aac
//
LOCUS       DATWEK010000012        44236 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.012, whole genome shotgun sequence.
ACCESSION   DATWEK010000012 DATWEK010000000
VERSION     DATWEK010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44236
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.012"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            356..790
                     /locus_tag="VCR92_000812"
     CDS             356..790
                     /locus_tag="VCR92_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267897.1"
                     /translation="MTKKNHGVFWGLLLGSAAASIAYLSLSSSKKDQLLKDSAKKIDD
                     LNAYLQDKSKQVLDAVSEKVQESKDAVEVYGGIAAETVEEKWQDTKDAVEVYGGIATE
                     TVEESLGQVKEKVEGIGEATSQTIQSKMEKLTSDKTDADDEK"
     gene            complement(840..1751)
                     /locus_tag="VCR92_000813"
     CDS             complement(840..1751)
                     /locus_tag="VCR92_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEP4267898.1"
                     /translation="MKTVRIFYNPNSGKKENQLARQVKDYFCQHGFSEDSVEVITPKD
                     ADQAFQLAKQAAKDKIDLVIPLGGDGTLNKIIGGIYEGGAHCLIGLVPSGTVNNFAKA
                     MHIPLQITEALDTILTGQIMQVDICKANQQYMISSLTLGLLADIAADVTAEEKRRFGP
                     LAFLKDSIRILKRNRSYAISLISHNHRIHLKTKFLLITMTNTIAGFPSFSPGAQADDG
                     YFQVYTMKKVSFFKFLWHINDFKQGEFSKAEEISHFQANTLSLLPQAKKQAILPRTRI
                     DGDKSDYLPIQLDIIPKAISIIVPTED"
     gene            complement(1868..2518)
                     /locus_tag="VCR92_000814"
     CDS             complement(1868..2518)
                     /locus_tag="VCR92_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEP4267899.1"
                     /translation="MNQTFKQSLPLSFSEEVANSVTHAIGAFAMLILLPISASYAYQT
                     YDLKAAIGISIFVISLFLMFLSSTIYHSMAYGSVHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVSGWLGYIIIVLQWGITLFGILYKIFAKRINEKFSLMLYIVMGWLVVFILPVII
                     QKTSLAFGLLMLFGGLSYTIGAVFYAKKRPYFHMIWHLFILLASALQFIAITFFML"
     gene            complement(2515..2955)
                     /locus_tag="VCR92_000815"
     CDS             complement(2515..2955)
                     /locus_tag="VCR92_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEP4267900.1"
                     /translation="MIFPSLPYWKDLPDLDLYLDQVLLYVNQCTDFSEVSDNKSLTAS
                     MINNYVKHGYVTKPIKKKYQKQQLARLIAISLFKTVFPIQDISRVLEELQAQADSESL
                     YNTFVTCWNQKAPIEEDIPPIVQVACQTVKDYHKTIYLLQEVIQ"
     gene            3174..4022
                     /gene="ylqF"
                     /locus_tag="VCR92_000816"
     CDS             3174..4022
                     /gene="ylqF"
                     /locus_tag="VCR92_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEP4267901.1"
                     /translation="MATIQWFPGHMSKARRQVQENVKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMILNKADLADATRTKEWKAYYESQGIKTLAINSKEQSTVKKVTEAAK
                     ELMADKIQRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKTHY
                     PSRLTKRFKNIPLEEEAPEIIMTLTRQLGFKDDYDRFYTLFVKEVRDGKLGQYTLDQV
                     GDMDVD"
     gene            4012..4803
                     /locus_tag="VCR92_000817"
     CDS             4012..4803
                     /locus_tag="VCR92_000817"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEP4267902.1"
                     /translation="MSTSIKAIKESLEAVTSLSDPLFQELATDARLGVQKALKSRQKA
                     IQADLAEEERLEAMLSYEKALYKEGYQAIAGIDEVGRGPLAGPVVAACVILPQHCKIK
                     GLNDSKKIPKSKHETIYQAVKEKALAIGIGIIDNQLIDEVNIYEATKLAMLEAIKQLE
                     GQLTQPDYLLIDAMTLDIAISQQSILKGDANSLSIAAASIVAKVTRDQMMANYDRIFP
                     GYGFAKNAGYGTKEHLQGLKAYGITPIHRKSFEPVKSMCCDSTNP"
     gene            4868..5704
                     /gene="dprA"
                     /locus_tag="VCR92_000818"
     CDS             4868..5704
                     /gene="dprA"
                     /locus_tag="VCR92_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEP4267903.1"
                     /translation="MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGC
                     KHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYPMALKEIYNPPVLLFFQGNLDLL
                     EKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
                     AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGIL
                     VVEAKNRSGSLITCQIGIEEGRDIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILS
                     EY"
     gene            5811..7940
                     /gene="topA"
                     /locus_tag="VCR92_000819"
     CDS             5811..7940
                     /gene="topA"
                     /locus_tag="VCR92_000819"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEP4267904.1"
                     /translation="MGTKTTTKPKTGTKKSTTKKKSTAKKNLVIVESPAKAKTIEKYL
                     GRSYKVVASVGHIRDLKKSSMSIDFDNNYEPQYINIRGKGSLINSLKKEAKAAKKVYL
                     ASDPDREGEAISWHLSHILGLDPQDNNRVVFNEITKDAVKHAFVEPRQIDMDLVDSQQ
                     ARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENDIKAFVPKEYWSIDG
                     LFKKGTKKFQATFYGINGKKTKLDNNNDVKEVLAKLTNEDFLVSKVDKKERRRNAPLP
                     YTTSSLQQDAANKINFRTRKTMMVAQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQ
                     NDAAQFIINRFGANYSKHGNRVKNTSGAQDAHEAIRPSSVNHTPDSIAKYLNKDQLKL
                     YTLIWNRFVASQMTAAVFDTVKVNLEQNGVIFVANGSQMKFDGYMAVYNDSDKNKMLP
                     EMAEGETVKKISTSPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLEVIQRRYY
                     VKLSAKRFEPTELGEIVNKLIVEFFPDIVDVAFTAEMEGKLDQVEIGEEQWQHVIDQF
                     YQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGHPMVIKLGRFGKFYACSNFPECRNT
                     KAITKEIGVTCPVCHKGQVIERKTKKNRIFYGCDQYPDCEFISWDLPIGRACPKSGDY
                     LIEKKVRGGKQVMCSNETCDYKEEKIK"
     gene            complement(8015..8899)
                     /locus_tag="VCR92_000820"
                     /pseudo
     CDS             complement(8015..8899)
                     /locus_tag="VCR92_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354842.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            8912..9457
                     /locus_tag="VCR92_000821"
                     /pseudo
     CDS             8912..9457
                     /locus_tag="VCR92_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631865.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            9472..10464
                     /locus_tag="VCR92_000822"
     CDS             9472..10464
                     /locus_tag="VCR92_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HEP4267905.1"
                     /translation="MKLKLYNVRGEEAVLAKKWADDNGIEISLTESPLTPETVKEAEG
                     FDGIANAQIGPLDDAIYPLLREMGIKQIAQRSAGVDMYNLDLATENDIIITNVPSYSP
                     ESIAEFTVTIALNLIRHVELIRENVKKQNFTWGLPIRGRVLGDMTVAIIGTGRIGLAT
                     AKIFKGFGCKVVGYDIYQSDAAKAVLDYKESVEEAIKDADFVSLHMPPTAENTHLFNA
                     DLFKSFKKGAILMNMARGALIETQDLLDALDAGLLSGAGIDTYEFEGPYIPKNFEGQE
                     ITDSLFKALINHPKVIYTPHAAYYTDEAVKNLVEGALNATVEIIKTGTTTTRVN"
     gene            10569..11234
                     /locus_tag="VCR92_000823"
     CDS             10569..11234
                     /locus_tag="VCR92_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SatD family protein"
                     /protein_id="HEP4267906.1"
                     /translation="MTYIALIGDIIQSKQLTDRSKVQKTLAAYLDDLNKTFAPYIISK
                     LSLTLGDEFQGLFQVDTPIFHLIDLINHHMDIPIRFGVGVGSILTDINPDISIGADGP
                     AYWHAREAIRYIHQKNDYGNTTLAFRTGHHNQDDVLNSLLAAGDAIKANWRASQWEIF
                     DTLLDLGIYEEYFDQQRLGKQLSLSSSALSKRLKSSHVKIYLRTRQSALNCLKQIKEE
                     TDD"
     gene            11227..11943
                     /locus_tag="VCR92_000824"
     CDS             11227..11943
                     /locus_tag="VCR92_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEP4267907.1"
                     /translation="MINGVSHYLAQTPTLTLFLICHVLSDYQLQSQQVADLKEKHLTY
                     LGYHLIGVSIPLICLTLIIPQAWLMSLLVMISHALIDWLKPKMANSLKWKREWIFLLD
                     QCLHIAISSFAGLRLAGVTLPNWLPISILMTVLFILLITKPTNIVFKLFFSKYQPDQG
                     EKMDTIIGAGATIGILERIVIGVCMFMGQFASIGLVFTAKSIARYNKISESPAFAEYY
                     LIGSLFSILSVFIAAWICFF"
     gene            12089..13435
                     /gene="trmFO"
                     /locus_tag="VCR92_000825"
     CDS             12089..13435
                     /gene="trmFO"
                     /locus_tag="VCR92_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEP4267908.1"
                     /translation="MSQSTATYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATP
                     QHKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEANRVPAGGAMAVDR
                     EGYAKSVTAELENHPLIEVIRDEITEIPDDAITVIATGPLTSDALAEKIHALNGGDGF
                     YFYDAAAPIIDKSTIDMSKVYLKSRYDKGEAAYLNCPMTKEEFMAFHDALTNAEEAPL
                     NAFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQ
                     LRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLL
                     TETFQSRNNPNLFFAGQMTGVEGYVESAASGLVAGTNAARLFKREEALVFPQTTAIGS
                     LPHYVTHADSKHFQPMNVNFGIIKELEGPRIRDKKERYEAIASRALADLDTCLASL"
     gene            13588..14994
                     /locus_tag="VCR92_000826"
     CDS             13588..14994
                     /locus_tag="VCR92_000826"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase subunit B"
                     /protein_id="HEP4267909.1"
                     /translation="MIQFGGFSMQQQVAITETVLRDGHQSLMATRLSIEDMLPVLTIL
                     DKIGYYSLECWGGATFDACIRFLNEDPWERLRTLKKGLPNTRLQMLLRGQNLLGYRHY
                     ADDIVDKFISLSAQNGIDVFRIFDALNDPRNIQQALRAVKKTGKEAQLCIAYTTSPVH
                     TLNYYLSLVKELVEMGADSICIKDMAGILTPKAAKELVSGIKAMTNLPLIVHTHATSG
                     ISQMTYLAAVEAGADRIDTALSPFSEGTSQPATESMYLALKEAGYDITLDETLLEQAA
                     NHLRQVRQKYLADGILDPSLLFPDPRTLQYQVPGGMLSNMLSQLKQANAESKLEEVLA
                     EVPRVRKDLGYPPLVTPLSQMVGTQAAMNVILGKPYQMVSKEIKQYLAGDYGKTPAPV
                     NEDLKRSQIGSAPVTTNRPADQLSPEFEVLKAEVADLAQTDEDVLTYALFPSVAKPFL
                     TTKYQTDDVIKVTAFIKA"
     gene            15037..15351
                     /locus_tag="VCR92_000827"
     CDS             15037..15351
                     /locus_tag="VCR92_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267910.1"
                     /translation="MTYSFIDILQVTLVSLFLVLTCLTGIMGLMMLSGKLLSQEKKTL
                     SQQASSIPQEQEADKLSGEALETLLAKDELARIAVMTSLAYASQEESGKRFEVIAVER
                     KS"
     gene            15351..15701
                     /locus_tag="VCR92_000828"
     CDS             15351..15701
                     /locus_tag="VCR92_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoyl-binding protein"
                     /protein_id="HEP4267911.1"
                     /translation="MKRYEVTVNGQVYEVSLLELADGETVQVSRPAAPATEKEMNANA
                     AGGGLQVKAPMSGTVLSIFATEGKAVKKGEAVLVLEAMKMENEILAPADGLVSKIHVV
                     ANQTVESEQVLISF"
     gene            15711..16841
                     /locus_tag="VCR92_000829"
     CDS             15711..16841
                     /locus_tag="VCR92_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEP4267912.1"
                     /translation="MLDVLNQMVQSSGLAHLTVNNLIMICLACFFLYLGIKKEYEPYL
                     MVPIAFGILLVNLPMAGLMDHPANGNPGGLLYYLYKGTSLGIYPPLIFLCLGASTDFG
                     PLIANPKTILLGGAAQVGIFLAFFLAIMLGMTPQEAASVGIIGGADGPTAIYVTTKLA
                     PDLLSTIALAAYSYMALVPIIQPPIIKLLTTKAERQVKMTQARTVSQKEKIIFPIMVT
                     IFVSLLVPSATTLVGCLMLGNLVREIKIVPKIVENLQQVVMFCITIILGLTVGAKANG
                     DLFLSATTLKIIALGLIAFAAGTAGGVLMGKVMYYLSGNKVNPMIGAAGVSAVPMAAR
                     VVQKVGQEEDPSNFLLMHAMGPNVAGVIGSAIASGALLAFFG"
     gene            complement(17042..17926)
                     /gene="citG"
                     /locus_tag="VCR92_000830"
     CDS             complement(17042..17926)
                     /gene="citG"
                     /locus_tag="VCR92_000830"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEP4267913.1"
                     /translation="MTKAVLTSISQLALKALLYEVSLSPKPGLVDRFDNGAHDDMSFM
                     TFIDSMIALSPFFQAYIETGFAYAKEEPLLLFNRLRQLGQKAEETMFCATQGINTHKG
                     LNFSMALLLGATGAYLARTPHLMTDLGCFSKEDTLAICRLVKPMTAHLIQTDLGHLNT
                     KKEFTYGEQLFVTYGIKGPRGEASEGFTTLTDHALPYFRQMISQNDPETSQLRLLVYL
                     MSIVEDGNLIHRGGIEAWKGVKADMRLLLQQDLSTTDLRLALSSYNQCLINQHLSPGG
                     AADLLALTFYFAFLEKLL"
     gene            complement(17919..18614)
                     /locus_tag="VCR92_000831"
     CDS             complement(17919..18614)
                     /locus_tag="VCR92_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP4267914.1"
                     /translation="MNPIIEAVKQNLDLSRNIPLKIAFYNALKTTIILRQIPVGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIKDACEIFEIRKALET
                     LATVQAMHLMTEEDFKVMHNLLEDCETFIAEDDTNRILDNFNAFNNLIYSYSQMVRLK
                     EIVTELQAYLVYFRKISISSVERRKRALSEHWMIYRGMKNKDHEQITLITHEHLNSSL
                     EFILKEMRPEQND"
     gene            complement(18772..20175)
                     /locus_tag="VCR92_000832"
     CDS             complement(18772..20175)
                     /locus_tag="VCR92_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEP4267915.1"
                     /translation="MLLTMLAYAMIIVFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFNADAKFVAFVGDGGIAKDLTAIGPMVMYGINNTAKTGIMLLFAILFFSVMLDAG
                     LFDPITEKMIRFAKGDPMKVLIATAVVAAAVSLNGDGTTTTLICCSAFLPIYKKLDMK
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLGVGPEILGYLAPGMILSLLYVICWVAP
                     SMGRKERARLGVIDLSEEDMRQLTDITDPDTLFIRRPKNFVFNAILTIGLITWLVAGS
                     FNKSIAMAPLLLFAVGTCIALMVNYPVLKDQSKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALVSAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYALIIFVI
                     FVVTIIAMGQMPLYIPQ"
     gene            20555..20878
                     /locus_tag="VCR92_000833"
     CDS             20555..20878
                     /locus_tag="VCR92_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267916.1"
                     /translation="MQFLQKWFKHSKKEKLKESSPLSTEIEPSENWEKIPAYIPADKS
                     DYKKVTLITSAIAAGDRPNSQFKVKRILKRNPEAITVSLIASSIAAGVYPESQFRVTS
                     IYCKR"
     gene            20935..21330
                     /locus_tag="VCR92_000834"
     CDS             20935..21330
                     /locus_tag="VCR92_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEP4267917.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPAQAAAPAQPISTPVPVPTEA
                     SPQVEEAQAPQPVAAAGADAIPSPMPGTILKVLVAVGDQVTENQPLLILEAMKMENEI
                     VASSAGTITAIHVGPGQVVNPGDGLITIG"
     gene            21375..22496
                     /locus_tag="VCR92_000835"
     CDS             21375..22496
                     /locus_tag="VCR92_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEP4267918.1"
                     /translation="MDTLIAGITSITIPQIVMMVIGALLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGSGVLTQVVNGVEQEGVFEALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQMTKILFPIIITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQADLF
                     LNVQTLLIIVFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            22684..22992
                     /gene="citD"
                     /locus_tag="VCR92_000836"
     CDS             22684..22992
                     /gene="citD"
                     /locus_tag="VCR92_000836"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEP4267919.1"
                     /translation="MDIKQTAVAGSLESSDLMITVSPNDEKTITITLDSSVEKQFGNH
                     IRQLIHQTLVNLKVTAAKVEAVDKGALDCTIQARTIAAVHRAAGVDQYDWKEIDSWNV
                     "
     gene            22980..23867
                     /gene="citE"
                     /locus_tag="VCR92_000837"
     CDS             22980..23867
                     /gene="citE"
                     /locus_tag="VCR92_000837"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEP4267920.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSSVETVVRVNGLDSCGALDIEAVVLAGVNVIRLPKTETAQDIV
                     DVEAVIERVERENSIEVGRTRMMAAIESAEGVLNAREIAKASKRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDG
                     KSVINPRQIPLVNEIYTPTEKEIDHSKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AERVIALATAAGVLSEEDI"
     gene            23870..25402
                     /gene="citF"
                     /locus_tag="VCR92_000838"
     CDS             23870..25402
                     /gene="citF"
                     /locus_tag="VCR92_000838"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEP4267921.1"
                     /translation="MVTNKLGRDIPQPYADQYGVFEGELANIKQYDESSRRIKPVKPG
                     DSKLLGSVREAIEKTGLTDGMTISFHHHFREGDFIMNMVLEEIAKMGIKNLSIAPSSI
                     ANVHEPLIDHIKNGVVTNITSSGLRDKVGAAISEGLMENPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDAYGNVNGTKGKATCGSLGYAMIDAKYADQVVILTDNLVPYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITNSPYFKEGFSF
                     QTGTGGASLAVTRFMREAMIKENIKASFALGGITNAMVELLEEGLVEKILDVQDFDHP
                     SAVSLGKHADHYEIDANMYASPLSKGAVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEVGIAINP
                     NRQDLVDHFKSLNVPQFSIEELKEKAYAIVGTPERIQYGDKVVALIEYRDGSLMDVVY
                     NV"
     gene            25395..25973
                     /gene="citX"
                     /locus_tag="VCR92_000839"
     CDS             25395..25973
                     /gene="citX"
                     /locus_tag="VCR92_000839"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEP4267922.1"
                     /translation="MCKDTYFSGEAIQLSDMLRAREERALRQLHLLKEYPEGSLLSVT
                     MNIPGPIKTSPKLLEVFDIVIKAIQTALADDKICYQLRLLPTTGYEYYLITSLPSRDL
                     KLKMIALETELPIGRLMDLDVLVLQNDLPHSISRTVLGGSPRQCFICSKEAKVCGRLR
                     KHSVEEMQTAISKLLHSFFNKDNQSSSSDKTG"
     gene            25988..27382
                     /locus_tag="VCR92_000840"
     CDS             25988..27382
                     /locus_tag="VCR92_000840"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEP4267923.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRAIRKAVKKTKLQMLLRGQNLLGYRNYADDVVRSFV
                     QKSIENGIDIVRIFDALNDPRNLQTAVSATKKFGGHAQVAISYTTSPVHTIDYFVELA
                     KAYQAIGADSICIKDMAGVLTPEIGYQLVKCIKENTTIPLEVHTHATSGISEMTYLKV
                     AEAGADIIDTAISSFSGGTSQPATESMAIALTDLGFDTGLDMQEVAKVAEYFNTIRDH
                     YREIGILNPKVKDTEPKTLIYQVPGGMLSNLLSQLTEQGLADKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNIISGERYKVVPNEIKDYVRGLYGQSPAPLAEGIKEKII
                     GDEAVIACRPADLIEPQMIYLRDEIAQYARSEEDVLSYASFPQQARDFLGRREDPFYD
                     VPVQEVTVQLDIQD"
     gene            complement(27492..28544)
                     /gene="citC"
                     /locus_tag="VCR92_000841"
     CDS             complement(27492..28544)
                     /gene="citC"
                     /locus_tag="VCR92_000841"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEP4267924.1"
                     /translation="MPYYTISKVFPSDKTTMASVKNLLHQEGIRLDAHLDYTCAIMNA
                     QNDVIATGSYFGNSLRCLCVSSAYQGGGFLNRIVSHLIDEEYALGNYHLFVYTKTSSA
                     AFFKDLGFTEIVHIDNHISFLENKKTGFQDYLMTLNKPEQTPGKVAAIVINANPFTLG
                     HQFLVEKAARENDWVHLFMVSEDQSLVPFSVRKMLIQEGLKHLDNIIFHETGPYLISQ
                     ATFPAYFQTEDNDVIKSQALLDTAIFLKIAQTLQITKRYVGEEPTSRVTAIYNEIMAE
                     QLQQAGILLDILPRKAINQQQDPISASTARQALKDSDWDLLAKLLPKTSLDYFCSLEA
                     QPIIKKIQATSSVKHY"
     gene            complement(28633..29115)
                     /locus_tag="VCR92_000842"
     CDS             complement(28633..29115)
                     /locus_tag="VCR92_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEP4267925.1"
                     /translation="MPKRIRKALGVVGKLMSIVPDTTEIIGKTIDNSRPIIEKRMEQK
                     HEKEMQLRTIDDVINLPVDQAQAHLEQLGFVVATIPAKPHKKWLHSNLNEVVAMSPKS
                     GKYKIGSLIKLYYITVDVLEKSQDLLDQENLRTVERNQKIADTFESVKHIRFPFKKWR
                     "
     gene            complement(29814..30884)
                     /gene="xerS"
                     /locus_tag="VCR92_000843"
     CDS             complement(29814..30884)
                     /gene="xerS"
                     /locus_tag="VCR92_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEP4267926.1"
                     /translation="MRRELLLEKIETYKAVMPWYVLDYYQSKLAVPYSFTTLYEYLKE
                     YKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
                     LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLD
                     LKDVNLNMMIIEVIRKGGKRDSVNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEY
                     RGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSS
                     TQVTDLYTHIVNDEQKNALDNL"
     gene            31354..32052
                     /locus_tag="VCR92_000844"
     CDS             31354..32052
                     /locus_tag="VCR92_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4267927.1"
                     /translation="MFSGHQLKTARLSKGITQSELGRLLHVNKMTISNWEKGKNIPNE
                     KHLNALLHLFNVTSDYFDPNYRLLTPYNQLTISNKEKVIGYSERLLNHQIDKKSKDLI
                     DKPSQLYAYRVYESLSAGTGYSYFGDGNFDVVFYDEQLEYDFASWVFGDSMEPTYLNG
                     EVVLIKQNSFDYDGAIYAVEWDGQTYIKKVFREDEGLRLVSLNKKYSDKFAPYSEEPR
                     IIGKIIANFRPLEI"
     gene            complement(32187..33749)
                     /gene="ffh"
                     /locus_tag="VCR92_000845"
     CDS             complement(32187..33749)
                     /gene="ffh"
                     /locus_tag="VCR92_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEP4267928.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKKLSESDVQEVTKEIRLALLEADV
                     ALPVVKTFIKRVRERAIGHEIIDTLDPTQQILKIVNEELTSILGSETAEIDKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTDHSAVDIVRKGLEQARENRNDYVLIDTAGRLQIDEKLMEELRDVKALAQPNEI
                     LLVVDSMIGQEAANVAYEFNHQLSITGVVLTKIDGDTRGGAALSVREITGKPIKFTGI
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAEKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMAGNPALANIKVDENQIARKRAIVSSMTPAERENPD
                     LLNPSRRRRIAAGSGNSFVEVNKFIKDFNQAKSMMQGVMSGDMSKMMKDMGINPNNLP
                     KNMPAGMPDMSSLEGMMGQGGMPDLSGLGGDMDMSQVFGKGFKGKIGQFAMKQAMKRQ
                     ANKLKKAKKKRK"
     gene            complement(33764..34105)
                     /locus_tag="VCR92_000846"
     CDS             complement(33764..34105)
                     /locus_tag="VCR92_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEP4267929.1"
                     /translation="MNIMEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEI
                     ADEFGVSRQAVYDNIKRTEKILETYEMKLHMYSDYVVRSEIFDDMIAHYPHDEYLQEK
                     ISILTSIDNRE"
     gene            complement(34194..34892)
                     /locus_tag="VCR92_000847"
     CDS             complement(34194..34892)
                     /locus_tag="VCR92_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP4267930.1"
                     /translation="MLPAYIKIHDAIKKDIDLGIWPIGSRLPSERHLAEHFTVSRMTL
                     RQAITLLVEEGILERRIGSGTYVASHRVQEKMRGTTSFTEIIRSQGRQPSSKLLSYQK
                     QLASDTEVKELNLDKTDLVIRMERIRYADSVPLVYEIASIPEKFIKTVKRADITEHFF
                     HSLIANGYEIGKSKQTIYAKLASERVASYLEVAKGHAILALTQVSYFTDGKPFEYVRS
                     QYIGDRFEFYLENN"
     gene            complement(34975..36408)
                     /locus_tag="VCR92_000848"
     CDS             complement(34975..36408)
                     /locus_tag="VCR92_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267931.1"
                     /translation="MLRKKRILGLFRPVELIFLGLLLSLVVSYLAWTNSFATLHNILA
                     TVGIVERSKDQQPRYHIGQAIQVQKSGPYHQWIGTINKQVEDIAENYRVSYHYEVVFP
                     IGKVTVSLPEHNLKEPDKPRFKKGDIVKLSSLTKKPHIKVYQGQLATIKQVKKRYDYS
                     LGGYQYDINLKDNLRLDGISEQDFVKPYYIRFNKGNSPEQNNRLLRKAFAYAKQHPNS
                     VISFPKGQFHIGSLPSQKDYFELPSDTAIIGHQTEFIIHGKMLWFGFPTGPKAEQGVR
                     NLVLTGVHFKANDLKKGDHFMIMADHGTDWHIYDNKFTMVHKRNSHIFDLGSLQNSLF
                     EKNQFIGYAPELVQDQQLLSKAQGHDFFSEVIQFDAAVHHFAWDGGLLSNIAPNYEAF
                     NQTRHLCHNITVSQNQFLPYIDPTGCLRAYSGSIGQHSSKVGVIRVLNNVFTSSIVTK
                     AKLTSWFMEPIHFPPNSPVIVAGNIIN"
     gene            36575..38137
                     /gene="guaA"
                     /locus_tag="VCR92_000849"
     CDS             36575..38137
                     /gene="guaA"
                     /locus_tag="VCR92_000849"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEP4267932.1"
                     /translation="MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKI
                     TAQELREINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLGGK
                     VVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLG
                     GKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEI
                     VWRQPFPGPGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            complement(38179..39402)
                     /locus_tag="VCR92_000850"
     CDS             complement(38179..39402)
                     /locus_tag="VCR92_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEP4267933.1"
                     /translation="MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQN
                     ERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKT
                     KKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRF
                     QANIYTQENLEMQFPKHTRRLIKDAKQRGVETYRASQSELHKFSKIVSLTEKRKNISL
                     RNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLNLINQDITRTQAHQKKRLKKL
                     EDQKASFERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYL
                     LYPKVFQDAYQDGIIWANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHI
                     ANTMYKIRKQLKNKH"
     gene            complement(39769..41313)
                     /locus_tag="VCR92_000851"
     CDS             complement(39769..41313)
                     /locus_tag="VCR92_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEP4267934.1"
                     /translation="MSILEVKQLSHGFGDRAIFENVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDEGKVEWSKYVTAGYLDQHTVLESGQTVRDVLRTAFDELFKTENRIN
                     EIYASMADDKADIAVLMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMESDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNHLDAEHIEWLKRYLQHYENAFVLISHDI
                     SFLNDVINIVYHVENQSLVRYTGDYYQFQAVYEMKQSQLEAAYERQQKEIANLQDFVN
                     RNKARVATRNMAMSRQKKLDKMDIIELQAEKPKPNFEFKQARTPSRFIFQTKNLVIGY
                     DYPLTKEPLNITFERNQKIAIVGANGIGKSTLLKSLLGVIEPLEGHIVTGDFLEVGYF
                     EQEVTGVNRQTPLEVVWDAFPALNQAEVRAALARCGLTSKHIESQIQVLSGGEQAKVR
                     FCLLMNRENNVLILDEPTNHLDIDAKNELKRALKAYKGSILMVCHEPDFYNGWVTDTW
                     DFSKLT"
     gene            complement(41447..42004)
                     /locus_tag="VCR92_000852"
     CDS             complement(41447..42004)
                     /locus_tag="VCR92_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEP4267935.1"
                     /translation="MSSQKLANYIELSMYAALIFISVQVLRIPIGMQFIHLGNALVVI
                     AVLIYGSKKGALVASLGLGIFDVLNGYASVVWITILESLAICLILHLVYERAMQSSKK
                     PKAIITITVIAALSKLTINLIKYLLLAYIGTQLPLSVSFWVALGKIGGSFGTSFVTLV
                     AVPLLYPVIKNLKEKVTIGQAKRGF"
     gene            complement(41982..42848)
                     /locus_tag="VCR92_000853"
     CDS             complement(41982..42848)
                     /locus_tag="VCR92_000853"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEP4267936.1"
                     /translation="MKRIIVANDLVGVGKVALSASIPLMASCLLEQVLLPTCLLSSHT
                     GGGQSPVKHTTSSILDVFLTDWDNKRIKFDGIFIGYFTTTRDGQKLLEWLSRKQLPLI
                     LDPIMADNGKLYQGFSQKHIEIMIKLTQKAELVLPNISEACLLTQTAYLAKNYDEEDI
                     RQVARKLAKLGPKQVVISGISFEEGSIGFAYYQSDSDQLTFHFGKQFPYHFYGTGDIA
                     SAIITAGFYYQLPLTQILDLVVSFLEKVLQNTLTLKRDLILGVAYESHLNYLTKSFKK
                     LLEEKNVISKIS"
     gene            42938..44206
                     /locus_tag="VCR92_000854"
     CDS             42938..44206
                     /locus_tag="VCR92_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEP4267937.1"
                     /translation="MTTKYQTIISNIEQDIQKQRLKKGDKLPSIRVLSKVYHCSKDTV
                     QRALLELKYRHLIYAVPKSGYYVLGNVSMPDNVLNLSLEDYNNMAYEDFRLCLNEALS
                     AKDKYLFHYYHKTEGLEELREALLLYLAENSVYSNKDQLLITSGTQQALYILSQMPFP
                     NAGKTILLEKPTYHRMEAIVAQLGLPYQTISRHFNGLDLELLESLFQTGDIKFFYTIS
                     RFSHPLGLSYNTKEKEAIVRLAQRYQVYILEDDYLGDFVKLKEPPIHYYDTHHRIIYL
                     KSFSMSVFPALRIGALVLPSGLKPYFLTQKSLIDLDTNLLMQKALALYLENGMFQKNL
                     RFIKRYLKQRERQLALFLKQNCPDIHYQLTPTHLVIDYTTSDSYRNFTLDKSDRIIIT
                     GKKRYLSIAINQQIQSKLNSLIKNTCGKSN"
BASE COUNT        13837 a         8395 c         8407 g        13597 t
ORIGIN      
        1 gttttcgtat taatgttttt ttatctatta cgatagataa ttttacttca atttttgatt
       61 gaaaatacta aaataagtga tgtggtcact ttgacaacca tttattggtc cttttagata
      121 agacaatttt gtggctcttc agttgaaagg atgtgttgtt gatgttagag gaaacaatca
      181 tgttaaatta actcaggctt aaagaccaaa aaaggagtga agtctattat gaaaaaaaga
      241 aattttaaac ttacagaaat gttacaattg gttttattag tggttcctgc tgtaaaactt
      301 gctaaaaaaa tgtttaacga tagtaaaaca ccgtctaaaa gaaagtaggt ctacaatgac
      361 taaaaaaaat catggcgttt tttgggggtt gttgcttgga tcagcagcag ctagcattgc
      421 ttacttaagt ttatcgtctt ccaaaaaaga tcaactcttg aaagatagtg ctaaaaaaat
      481 agatgatctc aacgcttact tgcaagataa aagtaagcaa gttctggatg cagtatcgga
      541 aaaagtacaa gaatccaaag atgctgttga agtttatggt ggtattgccg cagaaaccgt
      601 tgaagaaaag tggcaagata ccaaagatgc tgttgaagtt tacggtggta ttgccacaga
      661 aacagttgaa gaatctttgg gacaggttaa agaaaaggta gaaggaattg gcgaagctac
      721 tagccaaact atccaatcta aaatggaaaa actcaccagc gataagacag atgctgatga
      781 tgaaaaatag gttttaaaat acctttaaga taagacaaaa agtgccatta ggcacttttt
      841 taatcttctg ttggaacaat aatcgaaatg gcttttggaa tgatatctaa ttgaatgggc
      901 agatagtcac ttttatcccc atcaatcctg gtacgtggta atatcgcttg ttttttagct
      961 tgtggtagta agctaagcgt attggcttga aaatgactga tttcctctgc tttggaaaac
     1021 tcaccctgtt taaaatcatt aatatgccat aaaaatttaa agaaagagac ttttttcatg
     1081 gtataaactt ggaaatagcc atcgtcagct tgagcaccag gagaaaaaga aggaaaacca
     1141 gcaatggtat ttgtcatcgt gattaagaga aacttcgttt tcaggtgaat acgatggttg
     1201 tggctaatta aagagatggc atagctgcga tttcgtttca gtattcgaat actatctttt
     1261 aaaaatgcta gaggaccaaa gcgtcgtttt tcctcagccg ttacgtcggc agcaatatca
     1321 gccagtaatc ctaaggttaa actggaaatc atgtattgct ggttagcttt gcaaatatca
     1381 acttgcatga tttgtccagt caagatagta tccaacgcct cagtaatttg taaagggata
     1441 tgcatagcct tggcaaaatt attgactgtc cctgagggca ctaagcctat taaacaatga
     1501 gctcctcctt catagatgcc accgatgatt ttatttagtg tcccatcgcc accaagaggg
     1561 ataaccaagt caatcttgtc cttagcagct tgttttgcta attgaaaagc ctggtcagca
     1621 tctttagggg taataacttc tacagaatct tcggaaaaac catgttggca aaaatagtct
     1681 ttgacttgcc tagcaagttg gttttctttc tttccagaat taggattgta aaaaatccga
     1741 acggttttca tcaggtctct cctttgacag cttattactt gctatccatt ataccacttc
     1801 taagaattga tgtcttacat caaatcatca cattaagcct ctcaatcagt ctgagcatct
     1861 atttgtctta aagcataaag aaagtgatag cgataaattg gagggcagag gccaataaaa
     1921 taaagagatg ccaaatcatg tggaagtagg gtcttttttt ggcataaaat accgctccaa
     1981 tggtataaga caagccacca aataacatga gaagaccaaa agcaagacta gttttttgaa
     2041 tgatgactgg caagataaac acaacgagcc agcccataac gatataaagc atcaaactga
     2101 atttttcatt gatacgtttg gcaaaaattt tgtataaaat cccaaaaagc gtaatgcccc
     2161 actgcaaaac aataatgata tagcctagcc aaccagaaac aagggataag gcaacaggtg
     2221 tataacttcc tgcgatagca atgtaaatca tactgtgatc aataatgcgt agaatgtatt
     2281 tgtgaaccga accataagcc atggagtggt aaatcgtaga ggacaaaaac atcaaaaaga
     2341 gactgatgac aaagatggag ataccaatag cggctttaag gtcataagtt tgataagcat
     2401 agctggctga aataggaagt agaatgagca tagcaaatgc tccgatagcg tgtgtcacgc
     2461 tgtttgctac ttcctcacta aaagataagg gtaaactttg tttaaaggtt tggttcattg
     2521 gatcacctcc tgtaataaat aaatagtttt gtggtaatct ttgaccgttt gacaggcaac
     2581 ctgcacaatc ggtggaatgt cctcctcaat gggagccttc tgattccaac aggttacaaa
     2641 agtattgtaa agactttcag aatcagcctg tgcctgaagt tcctccaata cacgactaat
     2701 atcttgaata ggaaataccg ttttaaacaa actgatggca attaagcgcg ctagttgttg
     2761 cttttggtat tttttcttga taggtttagt cacataccca tgcttgacgt aattattaat
     2821 catagatgcc gttagtgatt tattatctga cacttctgaa aaatcagtgc actggttgac
     2881 ataaagtaag acttgatcca aatataagtc taaatcaggg aggtccttcc aataaggtaa
     2941 tgatggaaaa atcatagttt tgtctctcta tctagttttg ataactagat tatacgatta
     3001 atgaaaactt attgcaagca aaaactgtaa agacttaaaa gaggaaagta gaaatggcga
     3061 agtgaagcta atcatgctat aatgttaaag aattgattgg gatagatgcc ttctgtcgca
     3121 atcagactat tttatcacga agaagatgat gctacgaaag gaatttaaac tctatggcta
     3181 ctattcaatg gtttcctggg cacatgtcca aagccagaag acaggttcag gaaaatgtaa
     3241 agcatgttga ctttgtaact attttagtgg atgcacgctt accactttct agtcaaaatc
     3301 ccatgcttac aaaaattgtt ggtgataaac ctaaattaat gattttaaat aaagctgact
     3361 tggcagatgc aactcgaact aaagagtgga aggcttatta tgaaagtcaa ggtattaaaa
     3421 cattagccat caattccaaa gaacaatcaa cggttaaaaa agtaacagaa gcagccaagg
     3481 aactcatggc tgataaaatt caacgcttgc gagagcgggg cattcaaaaa gaaaccttgc
     3541 gaaccatgat tattggcatt ccaaatgctg gtaaatctac cttaatgaat cgcttggctg
     3601 gtaagaaaat tgctgtagtt ggcaataaac ctggtgtgac taaaggacaa caatggttga
     3661 agtccaataa ggaattggaa attctagaca ctcctggtat tttatggcca aaatttgagg
     3721 acgaattggt gggcttaaaa ttagctttaa caggtgctat caaggaccaa ttactaccaa
     3781 tggatgaggt cactattttt ggtttgaatt actttaaaac acattatcct agtcgcctta
     3841 ctaagcgttt taagaatatt cctcttgagg aagaagctcc tgaaatcatt atgaccttga
     3901 cacgccaact gggatttaaa gatgattacg accgtttcta cactttattc gtcaaggaag
     3961 ttcgtgatgg taaattaggt caatacacct tagatcaggt gggagatatg gatgtcgact
     4021 agtattaaag ctattaaaga aagcctggaa gctgttacta gcctctcaga ccccctcttt
     4081 caagaattgg caactgacgc taggttaggt gtccaaaaag cgctaaaaag tcgacaaaag
     4141 gctattcagg ccgatttagc agaggaagaa cgattagaag ccatgctttc ttatgaaaaa
     4201 gcgctttata aagaaggcta ccaagccatt gcaggtattg atgaggtggg acgtggcccc
     4261 ctagcaggtc ccgttgtcgc agcatgtgtc atcttacctc aacattgcaa aattaaaggt
     4321 ctgaatgatt ctaaaaaaat ccctaaatct aagcatgaga ccatttatca ggcagtgaaa
     4381 gaaaaggctt tggctatcgg tatcggtatt attgacaatc agcttattga tgaggtcaat
     4441 atttatgaag caaccaaact agctatgcta gaagccatta aacagttgga gggccaactc
     4501 acacaaccag attatctctt gattgatgcc atgacattgg atattgctat ttcgcagcag
     4561 tctattctta aaggcgatgc caattccttg tctattgcag cagcatcaat tgtagctaag
     4621 gtcaccagag atcagatgat ggctaactat gatcgcattt ttcctggtta tggcttcgct
     4681 aaaaatgcag gctatggcac caaagaacat ttacagggat taaaagctta cggcataacg
     4741 cctatccatc gtaaaagttt tgaacctgtt aaatccatgt gctgcgattc aactaatcct
     4801 taaaaagttc tgtttttagc agaatttttt tcttttttac gaataaatga agtaaggagg
     4861 taacttagtg aatcattttg aactttataa gctaaagaaa gctggactga ctaataaaaa
     4921 cattctcaat attcttgact accaagaaca ccaggaaaaa tcgttgtcac ttcgagatat
     4981 ggccgttgtt tctggttgta agcatccgtc tcactttata gaagcctata agcagttaga
     5041 tattcaaaaa ttaaaaatag aatttaaaca atttcctagt atttctatct tagataagca
     5101 ttacccaatg gcattgaaag aaatatacaa tccacctgtc ctcttgtttt ttcagggaaa
     5161 tttagacctt cttgagaaac ctaaattagc cattgtcggc tccagacgct caagcgatac
     5221 cggagtaaag tctgtccgta aaattcttaa agaactcggg aaccgttttg tgattgttag
     5281 cggacttgct cgaggtatcg acactagtgc tcatttagcc tgccttaaaa atgggggaca
     5341 aactatcgct attattggaa caggattgga tcgcttttac cctaaagaaa atagggagtt
     5401 gcaaactttc ttagggaaaa atcatcttgt gctaacagaa tacggtccag gagaagaagc
     5461 tttatcttat cactttccag aacggaatcg tattatcgca ggccttagcc gaggtattct
     5521 tgtcgttgaa gcaaaaaatc gttcaggttc cttgattact tgtcaaattg ggatagaaga
     5581 aggccgagac atttttgctg tcccaggaaa cattttggac gggaaatccg aaggttgcct
     5641 tcagttaatt aaagagggag caacatgcgt cacatcgggc atggatatcc tttcagagta
     5701 ctaaaaaagt taaagtttct tcctatatag cattttttta ttgacagttt cttaaaaatg
     5761 ggatattatg ctataagctt taaacaaact gttataggaa gtgtgtcgaa ttgggaacaa
     5821 aaactacaac taagccaaaa acgggtacta aaaagtccac cactaaaaag aaatcaacag
     5881 cgaaaaaaaa tctcgttatt gttgaatcac ctgccaaagc taagactatt gaaaaatatc
     5941 ttggacgcag ttataaagtt gttgcttcgg taggacatat tcgtgactta aaaaaatcgt
     6001 ctatgtctat tgattttgat aataattatg agccacaata cattaatatc cgtggtaagg
     6061 gatcccttat caattcttta aaaaaagaag ccaaagctgc taaaaaagtt tatttagcta
     6121 gtgacccgga tcgtgaggga gaggctattt cttggcattt gtcacatatc ttaggacttg
     6181 atcctcaaga taataaccga gtggttttta atgaaattac gaaagatgca gttaaacatg
     6241 cctttgtgga gcctcgtcag attgatatgg acttggtaga ttctcaacaa gcacgtcgtg
     6301 ttttggaccg tattgtggga tattccattt caccaattct ttggaaaaag gtcaaaaaag
     6361 gactttcagc aggacgtgtc cagtcggttg ctttaaaact catcattgac cgtgaaaatg
     6421 acatcaaagc atttgttcca aaggaatact ggtctattga tggtcttttt aaaaaaggaa
     6481 ctaaaaagtt tcaagcgact ttttacggta ttaatggcaa aaaaacaaag cttgataata
     6541 acaacgatgt caaagaggta ttagcaaagc taacaaatga agattttctt gtcagcaagg
     6601 ttgacaagaa agagcgacgt cgtaatgctc ccttacctta cacaacatca tctcttcaac
     6661 aagatgctgc taataaaatc aatttcagaa cgcgtaaaac catgatggta gcccaacaac
     6721 tgtatgaggg gattcattta ggagaaaatg gaactcaagg tttaattacc tatatgcgta
     6781 cggattctac tcgtatcagt ccagtagcac aaaacgatgc tgctcaattt attatcaatc
     6841 gctttggagc taattattca aaacatggta atcgtgtcaa aaataccagt ggtgctcaag
     6901 atgctcacga ggcgattcgt ccatctagtg ttaatcatac gccagactct attgccaaat
     6961 accttaacaa ggatcagtta aaactttata cgcttatttg gaatcgtttt gtggctagcc
     7021 aaatgacagc agctgttttt gataccgtaa aggtgaattt ggagcaaaat ggcgtgattt
     7081 ttgttgccaa tggtagccaa atgaagtttg atggttacat ggctgtttac aatgattccg
     7141 ataaaaacaa aatgttacct gagatggcag aaggagaaac ggttaaaaaa atatcgacct
     7201 ctccagaaca gcactttacg cagccaccag ctcgttattc tgaagcaact ctgattaaaa
     7261 cgctagaaga aaatggtgtt ggacgtccat caacttatgc cccaacctta gaagtgattc
     7321 aacgcaggta ctatgttaaa ttatctgcta agcgctttga gccaactgag cttggggaaa
     7381 ttgtcaacaa gcttattgtc gaatttttcc cagatattgt tgatgttgcc tttactgccg
     7441 agatggaagg taagctagat caagttgaaa tcggagaaga acaatggcaa catgtcatcg
     7501 atcaattcta tcaacccttt gtcaaagaat tgaataaggc tgagtctgaa attgaaaaga
     7561 ttcaaatcaa agatgagcca gctggttttg actgtgatgt ttgtggccac ccaatggtca
     7621 ttaagttagg acgttttggg aaattttacg cgtgcagcaa cttccctgag tgtcgtaata
     7681 caaaagccat cactaaagaa atcggtgtta cttgtccggt ttgtcataaa ggacaagtta
     7741 tcgagcgtaa aaccaaaaaa aataggatat tttatggttg tgatcagtat ccagattgtg
     7801 agtttatctc gtgggattta cctattggac gtgcttgccc taagtcaggt gactatctta
     7861 ttgagaaaaa agttcgtggt ggcaaacaag taatgtgtag caatgagacc tgtgattaca
     7921 aggaagaaaa aattaaataa aaaaagaatt ggaactcctt gtcttgttcc aattcttttt
     7981 ttatttacaa aggtattttt aactacaaaa atcgctagtt cgtttttaaa aggcttaaaa
     8041 attcctcaat aactggactg aaactcgcat catctcggta agcaatccca atagggtaaa
     8101 aattattttt atcttgcaaa ggaatccaaa ctaagttatc tacctgatta agactctcaa
     8161 aatcactcgg gaggatagtc aaggtattta aatcgtgcaa actatgaata agaacttccc
     8221 aatcattgtg tttaaagaca atatctggtt cataaccgag agctcggcat tttctaggaa
     8281 gcatttcgcc taacatgtag tgatcgttta aagaagcaat cttatagcct tttaaatctt
     8341 taagttttaa ctgaggatgt tgcgccaaag ggtgctgttt gaggagaacg atactgacct
     8401 tatagccttt tgtggacgtt tgtaatagct caatggtaat atccttttga atacttagaa
     8461 aggagaggag accaatatcg atttttcctt gggacaataa ttcttataat ttgcgagaac
     8521 catcctgtat aagcgataat tcaacatttg agtgagtagc cataaagatt gaaatttgtt
     8581 tcatgaattg tatagcaaac agtgatatta attcaacacg aatcatctct ttttttcttg
     8641 atttaattgc tgaatatccg caacaatttg attaaagtca tccacaaggt ctttgccttt
     8701 gtgataaaga atatctccag cttcggttag tagtagctgt caatcacttt gtgtaaaaag
     8761 cgtcgtgttc aaactaggac tctagccttt taattgattg agaaagagta tgttgcgtta
     8821 caaacaaact tttagcagcg tgggaatgat tttttgtttc agcaactgca ataaaatagg
     8881 ttaattatct aatatccata gtagatcctt catgattggt cagggaattg cgtctctact
     8941 tggtttacaa cctattttga tgtctctcct tattgccatg attttctgct tccttattgt
     9001 ttctccaatt acaacggtag gaattgctct tgcgattaac ttatctggta ttggttcagg
     9061 tgccgcaagc tttggacttt gcttagcagg ttgggctgtt aattcaaaag gaacttcact
     9121 tgctcacgtc ttgagatcac cgaaaatttc aatggccaac gttttatcaa aaccaaaaat
     9181 catgttgcca atgttatgtt ctgcagctgt acttggtgtt attggtgcta tctttaatat
     9241 tcaaggaaca cctgctagtg caggctttgg aattagtggt ttgatcggac ctatcaatgc
     9301 ccttaattta gctaaaggcg gatggtctcc agtaaatatt ctacttatca ttatcatttt
     9361 tgtaggggca cccattgtgc ttaatatgat ctttaactac ctctttatta aggtgcttaa
     9421 agtgattgat ccaatggatt acaagcttaa tatctaagaa aggaactttt gatgaaatta
     9481 aaattatata atgttagagg cgaagaagca gtcttagcaa aaaaatgggc tgatgacaat
     9541 gggattgaga tttccttgac agagtctccc ttaacccctg aaacggttaa agaagctgaa
     9601 ggctttgacg ggattgccaa tgcccaaatt ggtcctttag atgatgcaat ctatcctctc
     9661 ttaagggaaa tggggattaa acaaatcgct cagcgcagtg ctggtgtcga tatgtataac
     9721 cttgatttgg ccaccgaaaa tgacattatt atcacaaatg ttcctagcta ttctccagaa
     9781 tccattgcag aatttacggt tactattgcc cttaatttaa ttcgtcatgt ggagttgatt
     9841 cgtgaaaatg ttaaaaaaca aaatttcact tggggactcc ctatccgcgg tcgtgtttta
     9901 ggtgatatga cagttgcaat tatcggaact ggacgtattg gtctagctac tgctaaaatc
     9961 tttaaaggtt ttggctgcaa ggtcgttgga tatgatattt accaaagcga tgctgccaaa
    10021 gctgtcttgg actataagga atctgtagaa gaagcgatta aagatgctga ttttgtttcc
    10081 ttacacatgc caccaactgc agagaacaca caccttttca atgctgattt atttaaatca
    10141 ttcaaaaaag gggctatttt gatgaatatg gcgcgtggtg cccttattga gacgcaagat
    10201 ttactggatg ctttggatgc aggcttattg agcggagctg gtattgacac ttacgaattt
    10261 gaaggacctt atattcctaa gaattttgaa ggtcaagaaa ttacagattc actatttaaa
    10321 gctttgatta accatcctaa ggttatttat acgcctcatg cagcttatta tactgatgaa
    10381 gccgttaaaa acctagttga aggtgccctt aatgctacag tagagattat caaaactggg
    10441 acaacgacaa ctcgtgttaa ctaacaactg atttgacgtc cattataaag gaataattcc
    10501 aaaaattcct ttataatgga cttttttgca ttagtccgtt ataatagact gtaagaaagg
    10561 gggctcttat gacatatata gcgcttattg gagatattat ccagtccaaa caattgacgg
    10621 atcgttccaa agttcaaaaa actttagcag cttatttaga cgacctcaac aaaacctttg
    10681 ctccttatat tatttctaaa ttatccctaa cgttgggaga tgaatttcaa ggactttttc
    10741 aggtggatac tcctattttc catctgattg atttgattaa tcatcacatg gatatcccta
    10801 ttcgatttgg agtaggagta ggttctattc taacagacat caatcctgat attagtattg
    10861 gggctgatgg acctgcttat tggcatgctc gtgaggctat tcgttatatt catcaaaaaa
    10921 atgattatgg taatactaca ttagcttttc ggactggtca tcacaaccag gatgatgtat
    10981 taaacagttt actagcagct ggagatgcta ttaaagccaa ctggcgagct agtcaatggg
    11041 aaatttttga cacgctttta gatttgggca tttatgagga atactttgat caacaacgac
    11101 taggaaagca attatctctt agctctagcg ctttgtcaaa acgtctaaaa agtagtcatg
    11161 ttaaaattta tctgagaaca cggcagagtg cgctaaactg tctcaaacaa atcaaggagg
    11221 aaactgatga ttaatggtgt ctctcactac ctagctcaaa cccctacact taccctgttt
    11281 ctcatttgtc atgtgttatc agactaccag ttacaaagtc agcaagtagc tgatttaaaa
    11341 gaaaaacatt tgacttattt aggttaccac ttgattggag ttagcattcc cctaatttgt
    11401 ttaaccctca ttatcccaca agcatggttg atgagcctat tggttatgat aagtcacgcg
    11461 cttattgact ggctaaagcc aaagatggct aactctctaa aatggaaaag agagtggatt
    11521 tttctgctgg atcaatgctt acatatcgct attagttcat ttgctgggct aaggttagca
    11581 ggggtgacct tgcctaattg gcttccgata tctattttga tgaccgtttt atttatccta
    11641 ctcattacca aaccaactaa tattgtcttt aaactctttt tcagcaaata ccagcctgac
    11701 caaggagaaa aaatggacac gatcatagga gcgggggcta ccataggaat tctagagaga
    11761 attgttattg gggtgtgtat gttcatgggg caatttgctt caataggtct ggtctttacc
    11821 gctaaatcta ttgctcgcta taataaaatt tcggaaagtc cagcttttgc agaatactac
    11881 ctaattggtt ctttatttag tattctcagt gtttttatcg cagcatggat ttgtttcttc
    11941 tagttgaaaa gggttcccgt agaaagaggc tacacatagc ctcttttgct tttttcccct
    12001 ttctgttata ataagtcagg taactacatt agaaagattt gtgggtctgt catctaagag
    12061 atatcattcc cgaagaggta ttagtgactt gtctcaatca actgcaactt atattaatgt
    12121 tattggagct gggctagctg gttctgaagc tgcctatcag attgctaagc gcggtatccc
    12181 cgttaaattg tatgaaatgc gtggtgtcaa agcaacaccg caacataaaa ccactaattt
    12241 tgccgaattg gtctgttcca actcatttcg tggtgatagc ttaaccaatg cagtcggtct
    12301 tctcaaagaa gaaatgcgtc gcttggattc cattattatg cgtaatggtg aagctaatcg
    12361 tgtacctgct ggaggagcaa tggctgttga ccgtgagggg tatgcaaaga gtgtcactgc
    12421 agagttggaa aatcatcctc tcattgaggt cattcgtgat gaaatcacag aaatccctga
    12481 cgatgccatt acggttatcg cgacgggtcc attgacttca gatgccttgg cagaaaaaat
    12541 tcacgcgcta aatggtggcg acggattcta tttttacgat gcagcagcgc ctatcattga
    12601 taaatctacc attgatatga gcaaggttta ccttaaatct cgctacgata aaggcgaagc
    12661 tgcttacctc aactgcccta tgaccaagga agaattcatg gctttccatg atgcactaac
    12721 aaacgcagaa gaagcaccgc tgaatgcctt tgaaaaagaa aagtattttg aaggctgtat
    12781 gccgattgaa gttatggcta aacgtggcat taaaaccatg ctttatggac ctatgaaacc
    12841 cgttggattg gaatatccag atgactatac aggtcctcgc gatggagaat ttaaaacgcc
    12901 atatgccgtc gtgcaattgc gtcaagataa tgcagctgga agcctttata atatcgttgg
    12961 tttccaaacg cacctcaaat ggggtgagca aaagcgtgtt ttccaaatga ttccagggct
    13021 tgaaaatgct gagtttgtcc gctacggcgt catgcaccgc aattcctata tggattcacc
    13081 aaatctttta accgaaacct tccaatctcg taacaatcca aatcttttct tcgcaggtca
    13141 gatgactgga gttgaaggtt atgtcgaatc agctgcttca ggtttagtag caggaaccaa
    13201 tgctgctcgt ttgttcaaaa gagaagaagc gcttgttttt cctcagacaa cagctattgg
    13261 tagcttgcct cattatgtga ctcatgccga cagtaagcat ttccaaccaa tgaacgtcaa
    13321 ctttggcatt atcaaagagt tagaaggccc acgcattcgt gacaaaaaag aacgttatga
    13381 agctattgct agtcgtgctt tggcagattt agacacctgc ttagcgtcgc tttaacacta
    13441 aaaaagagtt ccttttcagt tgagttgctg aagaggactt ttttccttgc tgatttgagc
    13501 gctagctatg caaaagaatg cacaaaaaat acatgaatag actatggtca ctagaagcaa
    13561 tattatataa tgaatagtac tcattagttg attcagtttg gaggttttag catgcagcag
    13621 caagtcgcaa taacagaaac agttttacgg gacggtcatc aaagtttgat ggcaacgcgt
    13681 ttatctattg aggatatgct tcctgtcctt accatcttag acaagattgg ttattattcc
    13741 ctagagtgtt ggggaggagc aacctttgat gcctgtattc gttttttgaa cgaagaccct
    13801 tgggaaagac tgcgcacgtt aaaaaaaggc ttacctaata cccgtttaca aatgttatta
    13861 agaggccaaa accttttagg ctaccgtcat tatgcagatg acatcgttga caaattcatt
    13921 agtttatcag ctcaaaatgg gattgatgtt ttccgcattt ttgatgccct aaatgaccca
    13981 cgaaatatcc agcaagcctt aagagctgtg aaaaagacgg gtaaagaggc tcaactgtgt
    14041 attgcctata caactagccc agtgcacacg cttaactatt acctttcttt agtgaaagaa
    14101 ttggttgaga tgggagctga ttctatctgc atcaaagata tggctggtat tctaactccc
    14161 aaagcggcta aagagttagt atctggtatc aaagccatga ctaacttacc tcttattgtg
    14221 catacccatg caactagtgg catttctcag atgacctatc tagcagcagt agaagctggt
    14281 gctgatagaa ttgatactgc tttgtcacct tttagcgaag gcacttcaca acctgctaca
    14341 gaatccatgt atttagcctt aaaagaagca ggttatgata tcacattaga tgaaacgcta
    14401 ctggaacagg ctgctaatca ccttcgacaa gtccgtcaaa agtacttagc agatggcatt
    14461 ctggatccca gtcttctctt tccagaccca aggacactac aataccaagt tcctggaggc
    14521 atgttatcta atatgctatc tcagctgaaa caagccaatg ccgaatcaaa attagaagaa
    14581 gttttagcag aagttcctcg ggtaagaaaa gacttgggtt atcctccctt agtaacaccg
    14641 cttagccaaa tggtcgggac tcaagctgct atgaatgtga ttttaggaaa accttaccag
    14701 atggtgtcta aggaaattaa acaatacttg gcaggcgact atggcaaaac accagcacca
    14761 gtcaacgaag acttaaaacg aagtcaaatt ggctcagctc ctgtcaccac aaatcgtcct
    14821 gcagatcaac taagtcctga attcgaggtt ttaaaagcag aagtagcaga tttagcccaa
    14881 acggacgaag atgtgctgac ttatgccctc ttcccaagcg tagcaaaacc gtttttaaca
    14941 accaaatacc aaactgatga cgtcattaaa gtgactgcct ttatcaaagc ataataggct
    15001 atcttaatca gatagaaaca aaaatatgga gatcaaatga cctattcctt tattgatatc
    15061 ttacaagtta ccttagtatc cttgttctta gtgttaacct gtttaacagg gattatggga
    15121 ttaatgatgc taagtggtaa attattgtca caagaaaaaa aaactctctc tcaacaagct
    15181 tccagcattc ctcaagagca agaagctgac aagttgagtg gagaagctct cgaaactctt
    15241 ttagccaaag acgaattggc tagaattgct gttatgacta gtcttgctta tgctagccaa
    15301 gaagagtcag gaaaacggtt tgaagttatt gccgtggaaa ggaaatccta atgaaaagat
    15361 atgaagtgac tgtcaatgga caggtttatg aagtgagttt acttgaacta gctgatggag
    15421 aaactgttca agttagccgg ccagcagcac ctgctactga gaaagaaatg aatgccaacg
    15481 ctgctggcgg tggcctacag gtaaaggctc caatgtctgg aacagtcttg tctatctttg
    15541 ctacagaagg aaaagctgtt aaaaaaggag aagctgttct ggtcttagag gccatgaaaa
    15601 tggagaatga aattctagca cctgcagatg gtctggtttc aaaaattcat gttgtggcta
    15661 accaaacggt cgagtctgaa caagttttga tttcattcta ggaggaaacc atgctagacg
    15721 tactcaatca aatggtccaa tcgtcaggat tggctcatct aactgttaat aatcttatca
    15781 tgatttgctt ggcctgtttc tttttatacc ttggtatcaa aaaggaatat gagccttacc
    15841 ttatggtacc aatcgccttt gggattttac tcgttaattt gcctatggcg ggattgatgg
    15901 accaccctgc caatggtaat cctggtggcc ttctttatta cctatataag ggaactagcc
    15961 tagggattta cccaccttta atttttcttt gtttgggggc atcaactgac tttggtccct
    16021 tgattgccaa tcctaaaacc attttactag gaggcgcagc acaagttggg attttcttag
    16081 cctttttcct tgctattatg ttaggcatga cacctcaaga agcggcttct gtcgggatta
    16141 ttggtggtgc cgatggacca acagctattt atgtgacgac aaagttggcg cctgatttac
    16201 tctctactat cgccctagca gcttattctt acatggctct ggtacctatt attcaacctc
    16261 ctatcattaa actcttgact accaaggcgg aacgccaagt gaaaatgact caagcaagaa
    16321 ctgtttcaca aaaagaaaaa atcattttcc cgattatggt aacaatcttt gtcagccttt
    16381 tggttccaag tgctacaacc ttggttggct gtttgatgct gggaaatctg gtcagagaaa
    16441 ttaaaattgt tcctaaaatt gtagagaatc tccaacaagt ggttatgttt tgcattacta
    16501 tcattttagg attaaccgtt ggtgctaagg ccaatggaga tctcttttta tcagccacaa
    16561 ccttgaaaat tattgccctt gggctaatcg cctttgctgc tggtacagca gggggtgtct
    16621 tgatggggaa ggtcatgtac tatttatctg gtaacaaagt gaaccctatg ataggagcag
    16681 caggtgtttc agctgttccg atggcagcgc gagtggtcca aaaggtcgga caagaagaag
    16741 atccaagtaa tttcttactc atgcacgcca tgggacccaa tgtagctggc gttattggct
    16801 cagccattgc ttcaggtgcc ttgctggcct tctttggcta attgtgaaaa aggattagta
    16861 aattaatctt aataaatcat tatcaggagt tggaagcaat ctaactcctt ttttagtaga
    16921 aagctcgagt gataaactat tccaaaataa ttataaaaaa agactgtcct gattgtacgg
    16981 actatatcaa ttgactttta tagtctagct gaaatagcag tgcaaaacta agacactcgt
    17041 tttaaagtag tttttctaaa aaagcaaaat aaaaggtcag agccaataaa tctgccgcgc
    17101 ccccagggct taaatgctga ttaatgaggc attgattgta ggaggacaaa gccaatctta
    17161 ggtcagttgt tgataaatct tgttgcagga gtagtcgcat atctgcttta acgcctttcc
    17221 atgcttcaat ccctccacga tgaatcagat ttccatcttc aacaatagac atcaaataaa
    17281 caagaagacg aagctgactg gtttcggggt cattttgact tatcatctga cgaaagtagg
    17341 gcaaggcatg gtctgttaag gtcgtgaatc cctcgcttgc ctcaccccga ggtcctttga
    17401 tgccataagt tacaaagagt tgctccccat aagtgaactc ttttttagtg ttcaaatgac
    17461 caaggtctgt ttgaatcaaa tgtgccgtca taggttttac taaacgacag atagctagag
    17521 tatcttcctt gctaaaacac cctaaatcag tcattaagtg aggtgttctt gctagatagg
    17581 ccccagttgc accaagaagt aaagccatgg aaaaattcag gcctttatga gtgttaattc
    17641 cctgagtagc acaaaacatg gtttcctcgg ccttttgacc tagttgtcta agacggttaa
    17701 acagaagaag tggctcttct tttgcataag caaaacctgt ttcgatataa gcctgaaaaa
    17761 aaggagagag tgctatcata ctgtcgataa aggtcataaa ggacatgtca tcatgggcac
    17821 cgttatcaaa tcgatcaact aaaccaggtt ttggagatag tgagacttca taaagcaaag
    17881 cttttaaggc cagttgacta atacttgtta gaactgcctt agtcattttg ctcaggcctc
    17941 atttctttta agataaattc aagtgagcta ttcaagtgtt catgtgtaat caacgtaatt
    18001 tgctcatgat ctttgttctt catacctcgg taaatcatcc agtgttcaga tagagctcgt
    18061 ttacggcgtt caactgaaga aatcgaaatt tttctaaagt agaccaaata agcttgcaat
    18121 tctgtcacaa tttcttttaa gcggaccatt tggctatagc tgtaaatcaa attgttaaag
    18181 gcattaaaat tatccaaaat acgattggtg tcatcctctg cgataaaggt ttcacagtct
    18241 tccaacaagt tatgcatgac tttaaaatct tcttctgtca ttaaatgcat cgcttgcact
    18301 gttgcgagag tctctagagc ttttcgaatt tcaaaaattt cacaggcatc cttgatacta
    18361 actcctttga caataatgcc ttttttagga atgtgctcta caaggtgttc ttcagacaat
    18421 aatcccaaag cgtagcgaat aggtgtcctg ctaatattaa gcgcaatgga aaactctttt
    18481 tcattaatgc ggcttccaac aggaatttgt cgcaaaataa tggtcgtttt aagagcgtta
    18541 taaaaggcta ttttcaaagg gatatttctt gataggtcaa gattttgttt aacggcttcg
    18601 ataataggat tcatgtcatc tccttaatgc tagtgtcctc actttattat acttaaattt
    18661 gtgaaacatt ccaataggac tagatgagtt ctgaaaaatt aaagccatgc tcacaaaagg
    18721 acatgacttt aatcatctca taaggaataa ggtagtagtg ttatcgttgg tttattgtgg
    18781 aatgtaaagt ggcatttgcc ccatggcaat aatggttacc acaaagataa caaagatgat
    18841 aagggcatat ttagcagcct ctttttgcca ttcccccatg tcaagacctg tcaagcgaag
    18901 aagaagataa atgaaggcaa ctaatggact aagtaagtgg aaggcttgtc ccatgaggga
    18961 agcaagtgcc atagccatgt tactgaaacc atattcagca ccagcttctg caagaacagg
    19021 caagatacca tagtaaaaac catcattgga gataaagaag gtaccaggtg cagaaactaa
    19081 ggcaataaca agaccccaga aacctgccag ttgttttgga ataatggttg caaaactttg
    19141 tgcaagagcg ctagccatac cagaaccttg gaaaagaccc ataaagatac cagcagcaaa
    19201 gactaagata accacttgaa ccgcatcacc agcattgtca ccaatgcgtt ttgattgatc
    19261 tttaagtact gggtaattga ccatcaaggc gatacaagtt cccaccgcaa aaagaagaag
    19321 cggtgccata gcaatagatt tgttgaaaga gccagcaact aaccaagtga ttaatccaat
    19381 ggttaggata gcattgaaaa caaagttttt aggacgacga ataaaaaggg tatctgggtc
    19441 agtaatgtct gtgagttgac gcatgtcttc ttcagacaag tcaataacac caagtcttgc
    19501 acgttcttta cgccccatgc ttggagcaac ccaacaaatc acataaagaa gagataaaat
    19561 catacccggt gcaagatagc caagaatttc aggaccgaca ccaagaacag acatcgcacg
    19621 agcagtaggg ccaccccatg gcagtaagtt cataatagta ttttgaagaa taatcaagac
    19681 acctaggttc atgattttca tgtccaattt tttatagata ggtaagaaag cagagcaaca
    19741 aattaaagta gtggttgttc catcaccatt aagagatact gcagcagcaa cgacagctgt
    19801 tgcgataagc accttcattg gatcaccttt agcaaagcga atcatctttt cagtaatcgg
    19861 atcaaacaat cctgcatcta acatgacaga gaagaacaaa atggcaaata gcaacatgat
    19921 acctgtttta gcagtattgt tgataccata cataaccatt ggtccgatag ctgttaggtc
    19981 tttagcaatt ccaccgtcac caacaaaggc aacaaatttg gcatctgcat tgaagtcagc
    20041 tgaaccagtc agtataacag caatcgtcat gattaatgga atcatgacca aagcagtaaa
    20101 aggggtcatt tttttcttca ttaccacgta cataaagaca ataatcatgg cataagccag
    20161 cattgttaat aacatcattg ttatctcctt tttcaagtta tgatttcagt atagatgaaa
    20221 gcgcttataa aataaatact tctttgtgca gaaagacaca aaaaaaacaa tttgaaaatt
    20281 aattttgaaa accattttta ttacatcaga tgactttaaa ttttctataa taatgatgaa
    20341 cctagttaga tcaagctttt cttgctatca gtatcttgat ctcagttttt caacagttac
    20401 ctaaaaataa aataaaaggt aactgttgaa aaactttatg aaacattgaa agcgctctta
    20461 gaaagaacac aaaaaagcca tctcaaaaaa gattggtagt atataataaa cttactagtt
    20521 ccctaaatag gtaaatgtga aaaagaggta gctcatgcag tttttacaaa aatggtttaa
    20581 acactctaaa aaagagaagt tgaaagaatc ctcgcccctt agtacagaaa tagaaccttc
    20641 tgaaaactgg gaaaagattc ccgcttatat tcctgcagac aaaagtgatt acaaaaaggt
    20701 tactttaatt accagtgcta ttgctgctgg cgatagacct aatagtcaat tcaaggttaa
    20761 acgcattctc aagcgcaatc ctgaggcaat cactgtttct ttaattgctt caagtatcgc
    20821 tgcaggtgtt tacccagaaa gtcagtttcg ggtgacatcc atctattgca aaaggtagtc
    20881 gttgaacgat actttagacg aactcatgac acaataacat ataggagaaa aatgatgtta
    20941 cgaaaattta aaattaccat tgacggtaaa gaatatcttg tagaaatgga agaaatcggt
    21001 gctcctgccc aagcagctgc ccccgctcaa ccaatatcca ctccagtacc tgtccctact
    21061 gaagcaagcc cacaagtgga ggaagcgcaa gcaccacagc cagtagctgc agcgggagcg
    21121 gatgccattc catcaccaat gcctggaacc atcttaaaag tcttagtagc agtgggagac
    21181 caagtaactg aaaatcagcc actattgatt ttagaagcca tgaagatgga aaatgagatt
    21241 gtggcctcat cagcaggaac cattacagct atccacgtcg gtccaggtca agtggtcaat
    21301 cctggtgatg gtctcattac aattggttaa tagtactata actagaataa atagacagaa
    21361 aaggaagtga atttgtggac actttaatcg caggaataac ctccatcacc attcctcaaa
    21421 ttgttatgat ggtcatcggt gccctcttaa tgtatctagg aattaaaaaa gaatacgaac
    21481 caaccttact tgtccccatg ggacttggaa ccattctcgt taacttccct ggttcaggag
    21541 ttttaaccca agtggttaac ggagtcgagc aagaaggggt ttttgaggct ctcttcaatt
    21601 ttgggattgg aacagaactt ttcccactgt tgattttcat tggtattggc gccatgattg
    21661 actttggtcc cttgcttcaa aacccattca tgctcttgtt tggtgctgca gcgcaatttg
    21721 ggattttctt tgttgttgtt gttgctgtac tggctggctt tgacattaaa gaagcagctt
    21781 caatcggcat tatcggagca gcagatggac cgacttctat ctttgttgcc aaccaactgg
    21841 ccaaggattt actgggtcca attacggttg cagcctattc ttacatggct ctggttccta
    21901 ttatccaacc atttgccatt aaattagtga caacgaaaaa agagcgccgt atccgtatga
    21961 cttacaaagc tgagaatgta tctcaaatga ctaaaatctt attcccaatc atcattacct
    22021 tagtagcagg gttcatcgcc ccaatttctc tacctttagt tggctttttg atgttcggta
    22081 acttattacg tgagtgcggt gtgctcgatc gcctgtcaca aactgctcaa aatgaattgg
    22141 taaacattat tagtatcttg cttggattga ccatctctat taaaatgcag gcagacctgt
    22201 tcttaaatgt acagacactc ttaattatcg tctttggttt acttgctttt atcatggatt
    22261 ctatcggtgg ggtcatgttt gccaaatttc tcaatctctt ccgaaaagag aagattaatc
    22321 caatgattgg cgctgcgggt atttcagctt ttccaatgtc aagtcgtgtc attcaaaaaa
    22381 tggcaacaga tgaagacccg caaaacttta tcctcatgta tgctgtaggt gccaatgtct
    22441 ctggccaaat cgcctctgtt atcgcaggtg gtttgttgct agcttacttt agctaagaaa
    22501 ggaaggaaag cttatgacaa ttaatatgga ccatttgatt agttcctttg agctaatggc
    22561 gcttggtatg gcaggtgtct ttatcgtgtt aggaattctc tatcttgtcg cagagatcct
    22621 gatcaaactt ttcccagtta gtaaataaca atatcattta agaaaatcaa ggaggtaaac
    22681 gcaatggata ttaaacaaac tgccgttgct ggttcacttg aatcaagtga cctaatgatt
    22741 acagtatccc ctaatgacga gaaaaccatt acaataaccc tagacagtag tgttgaaaaa
    22801 caatttggca atcacattcg tcaactcatt catcaaaccc tagtgaattt gaaggtgacg
    22861 gctgctaaag tagaggctgt tgataaaggc gctttagatt gcaccattca agcgagaacc
    22921 atcgcagctg ttcatcgcgc agctggtgtt gaccaatacg attggaagga gattgactca
    22981 tggaacgttt aagaagaaca atgatgtttg tgccaggtgc caatgctgct atgcttcgag
    23041 atgctccttt gtttggtgct gattcaatca tgtttgactt ggaagattct gtttcactca
    23101 aagaaaaaga cacttctaga gctctcgtcc attttgcgct aaaaactttt gattattcga
    23161 gcgttgaaac ggttgttcgt gtgaatggtc ttgattcttg tggggcttta gacatcgaag
    23221 ctgttgtttt ggcaggtgtc aacgtgattc gtcttccaaa aacagagact gcacaagata
    23281 tcgttgatgt ggaggctgtt attgaacgtg tcgaacgtga gaacagcatt gaagttggtc
    23341 gcacacgtat gatggcagcc attgaatcag ccgaaggtgt tctaaatgct cgtgagattg
    23401 ccaaagcttc taagcgcttg attggtattg ctcttggggc agaagactat gtcacgaata
    23461 tgaaaacgcg tcgttaccca gatggtcaag aattattctt tgctcgtagc atgattttac
    23521 atgctgctcg tgctgctgga attgctgcca ttgatactgt ttattctgat gtcaataata
    23581 cagaaggatt ccaaaacgaa gttcgtatga tcaaacagtt aggatttgac ggtaaatcgg
    23641 tcatcaaccc tcgccaaatt cctctggtca atgagattta taccccaacc gaaaaagaaa
    23701 ttgaccattc caaacaagtc atctgggcaa ttcgtgaagc tgaaagcaaa ggctctggcg
    23761 ttatttcctt aaatggaaaa atggttgata aaccaatcgt tgaacgtgca gaacgtgtca
    23821 ttgccctagc aacagcagca ggtgttttat ctgaggagga catttaaaga tggtaacaaa
    23881 taaactcggt agagatattc ctcaaccata cgccgaccaa tacggtgtct ttgaaggaga
    23941 actcgcaaat atcaaacagt atgacgaatc aagtcgccgt attaaaccag ttaagcctgg
    24001 agattctaaa ttactaggat ctgttcgtga agcgattgaa aaaacaggtt taacagatgg
    24061 catgaccatt tctttccacc accatttccg tgaaggggat ttcattatga atatggtctt
    24121 ggaggaaatt gccaaaatgg gcattaaaaa cctgtctatt gccccaagtt ccatcgctaa
    24181 tgtacatgag cctttgattg atcacatcaa aaatggtgtg gtcactaaca tcacttcatc
    24241 tggtcttcgt gacaaagtag gggcagccat ctcagaagga ctaatggaaa atcctgtggt
    24301 tattcgctcc catggtggtc gcgctcgtgc cattgctagt ggggatatcc atattgatgt
    24361 tgcctttctg ggcgccccaa gttcagatgc ttacggaaat gttaatggga caaaagggaa
    24421 agcaacctgt ggttctttgg gctatgccat gattgatgcc aaatatgcgg atcaggtggt
    24481 tatcttgaca gataatttgg ttccttatcc taatacccca atcagcattc ctcaaacaga
    24541 tgttgactat gtggtaacag tggatgctat cggagatcct caaggaatcg ccaaaggggc
    24601 aactcgtttt acgaaaaatc ctaaagaact cttaattgca gaatacgccg ctaaagtaat
    24661 caccaactct ccttatttta aagaaggatt ctctttccaa actggaacag gtggcgcttc
    24721 tttggcagta acccgtttca tgcgtgaagc tatgattaaa gaaaatatca aagctagctt
    24781 tgctcttggt ggtattacca atgctatggt ggagttgctc gaagaaggac tggttgaaaa
    24841 aattcttgat gtccaagact ttgatcaccc atcagctgtt tctcttggta agcatgctga
    24901 ccattatgaa attgatgcca acatgtatgc ctcacctttg agcaagggtg ctgttatcaa
    24961 tcaattagac acttgtattt tatcagccct tgaagtcgat actaacttca atgttaatgt
    25021 gatgacagga tctgacggcg tgattcgtgg cgcttctgga ggacactgcg acactgcctt
    25081 tgcggctaag atgagtttgg ttatttcacc acttatccgc ggacgcatcc caacttttgt
    25141 agatgaggtt aatacggtca ttacaccagg aacaagtgtc gatgtggtcg tcacagaagt
    25201 gggaattgcc attaacccaa atcgtcaaga cttagtagac catttcaaat ccctcaatgt
    25261 gccacaattt agtattgagg agctaaaaga gaaggcttac gctatcgttg gcacacctga
    25321 gcgtattcaa tatggtgata aggttgttgc tcttattgaa taccgtgatg gtagcctcat
    25381 ggatgtggtt tacaatgtgt aaagacactt atttttcagg cgaagctatc caacttagtg
    25441 atatgttaag agcccgcgaa gaaagagctc tgcgtcagct gcatttatta aaggagtacc
    25501 cagaaggtag cttattatcg gtcaccatga atatccctgg accaattaaa acctctccta
    25561 aacttcttga agtttttgat atagtgatta aggccattca aactgcctta gctgacgata
    25621 agatttgtta ccagttgcga ttactgccta caacgggtta tgagtattac ctcatcacaa
    25681 gtctacctag ccgcgacctg aagttaaaaa tgatagcctt agagacagag ttgccaatag
    25741 gtcgtctcat ggatttagat gtcttggtct tgcaaaatga tctgcctcat tcaattagca
    25801 gaaccgtatt aggaggctcc cctaggcaat gttttatctg ttctaaagag gccaaagtct
    25861 gcggtcgcct acgtaagcac agtgtcgagg agatgcagac tgctatttca aaattactcc
    25921 attcattttt caataaagac aaccaatcat cgtcatcaga taagacaggt tgatgaggag
    25981 aacaattatg acgaaaatcc gtataacgga aacagtttta cgtgatggtc aacaaagtca
    26041 gattgccaca cgtatgacaa ccaaggaaat gattcctatt ctcgaaacgc tagacaatgc
    26101 tggttatcat gcccttgaaa tgtggggagg agcaaccttt gattcctgcc tacgcttttt
    26161 aaatgaagac ccttgggaac ggctaagagc catccgtaaa gcagtgaaaa agactaaact
    26221 tcagatgctc ttacgcggac aaaaccttct tggatatcgc aattatgctg acgatgtggt
    26281 cagatccttc gttcaaaaat ccattgaaaa cgggattgat attgtccgta tcttcgatgc
    26341 tttaaatgac cctcgcaact tgcaaacagc tgtttcagcg actaaaaaat ttggagggca
    26401 tgctcaagtt gccatttctt acacgacaag tccggtacat accattgact actttgttga
    26461 attggcgaaa gcttaccaag ctatcggagc ggactccatt tgtatcaaag acatggctgg
    26521 tgtcttaact cctgaaatag gttaccaatt ggtcaaatgt atcaaggaga atacaactat
    26581 tcctcttgag gttcataccc atgctaccag tggtatttca gaaatgactt acttaaaagt
    26641 agcagaagca ggagctgata ttattgatac ggcgatttcc tctttttcag ggggaaccag
    26701 tcagcctgcc acagagtcaa tggcgattgc cttgacggat ttaggctttg acacaggctt
    26761 ggatatgcaa gaggtggcca aagttgcaga atatttcaac actattcgtg accactatcg
    26821 agaaataggg attttaaatc ctaaagtcaa agatactgag ccaaaaacat tgatttacca
    26881 agttccaggt ggcatgctat caaacctatt gagccaatta accgagcaag gcctagctga
    26941 taaatacgaa gaagtcttag cagaagtacc taaagtaagg gctgatcttg ggtatccgcc
    27001 actcgtaacg ccattatcac aaatggttgg aacacaggcc ttgatgaata tcatctcagg
    27061 ggaacgctac aaggtagttc caaatgaaat caaagactat gttcgagggc tatacggtca
    27121 atcaccagcc ccattagcag aaggtatcaa agagaaaatc attggtgacg aagcagtcat
    27181 tgcttgcaga ccagctgact taatcgagcc tcaaatgatt tatctacgtg acgagattgc
    27241 tcaatacgct cgttcagaag aagacgtgtt aagctatgcg agtttcccac agcaagccag
    27301 agatttcttg ggacgccgtg aagatccttt ctatgatgtt ccggttcaag aagttactgt
    27361 acaactggac attcaagact aacagggaat gactaatcct cttaaccatt aatctccttg
    27421 gtgaaacgca tttgctgtaa gaacaatacc aaaaacctac ctgattttga taatcagata
    27481 ggttttttat cttagtaatg tttgacagat gaagtggctt gtatcttttt aataatgggt
    27541 tgggcttcta gcgaacaaaa ataatctaaa gacgttttgg gaaggagttt tgccagaagg
    27601 tcccaatcac tatctttcaa tgcctgccta gccgttgagg cactgatagg atcttgctgc
    27661 tgattgatag ctttccttgg caaaatatct aggaggatac cagcttgctg caactgctct
    27721 gccatgattt cattgtaaat agcagttact cggctggttg gctcttctcc aacgtatctt
    27781 tttgtaatct gtaaggtttg agcaatcttt agaaaaatag cagtatccag caaagcttgg
    27841 cttttgatca catcattgtc ttccgtttgg aaataagctg gaaaggttgc ctgactaatc
    27901 aaataaggac ctgtttcatg aaagataatg ttatcaagat gtttcaatcc ttcttgaatc
    27961 aacatttttc gtactgaaaa aggaaccaag ctttggtcct cactgaccat aaacagatga
    28021 acccaatcat tttctcttgc agctttctct actaaaaatt gatgccctaa ggtaaagggg
    28081 ttagcgttga taacaatagc agcgacttta ccaggtgttt gctcaggctt attaagtgtc
    28141 atcagataat cttgaaaacc agttttttta ttttccaaga aactgatgtg attgtcgata
    28201 tggacaattt cagtaaaacc aagatctttg aaaaaagcag cagaagaggt cttcgtataa
    28261 acaaaaagat gatagttgcc aagggcatat tcttcatcaa tgagatgact cacaatccta
    28321 ttaagaaatc ctccaccttg ataggcactg gatacgcaaa gacagcgcaa gctatttcca
    28381 aagtaagaac cggtagcaat cacatcattt tgcgcattca tgatggcaca agtataatct
    28441 aaatgagcat ccaaacgaat accttcttga tgaagcaggt tctttacact agccattgtc
    28501 gttttatctg aaggaaagac ttttgaaata gtgtagtaag gcatttcttc tccgtatctt
    28561 taattttatt gaatcataac ataacttagt accaaaacag gctgatctat ctaaaggcaa
    28621 ctctgttttt tatcaacgcc attttttaaa aggaaatcga atgtgtttga cagactcaaa
    28681 agtatcagcg attttttgat tgcgttccac agtccgcaag ttttcttggt ctaataagtc
    28741 ttgacttttt tccaaaacat caacagtaat gtagtagagt ttgatcaggc ttcctatctt
    28801 atatttacca gattttggag acatagcaac cacttcattg agattactat gaagccattt
    28861 tttatgaggc ttagcaggta tagtggctac tacaaagcca agttgttcca aatgagcttg
    28921 tgcctgatca acaggaagat taatcacatc atctatcgtg cgtagttgca tctctttttc
    28981 atgtttttgt tccatacgtt tttcgataat tggtcgactg ttatcaatcg tttttccaat
    29041 aatttcagta gtgtcaggaa caattgacat cagtttccca actactccta gagcttttct
    29101 tattctcttt ggcatctttt atctcctcaa gtcgtttctt tttattataa caaaatgtct
    29161 aaaaatagta tgcgataaac cttgttctaa aaggttaaat agatcaattc aaggaaaaaa
    29221 taggagggga gccgacaaaa aacacaaaga ttctaaaaaa gtcaagctat tttagtttag
    29281 cctttgtcaa tcgtatcagt tcaaatagaa aatacaaatt ttgacaagaa tttatttatg
    29341 taacaaactg tgtttttgat tcttcagtct atctaacgat aatgttatct gattcttgtt
    29401 ttcaaccaat tgatgttaaa gaagctgtct tcatgattct ctaatattcc ttcaatttta
    29461 gctttatatt actctaagtt atcagtaatg acattaagta gtttaacaag aataatccta
    29521 aaagctactt tacaaaataa cgtattatca tactaaataa aagtactgac atactaaaaa
    29581 caggcttatc tcatcttttt gatgagaacc ctactagatt taatctataa acatcacaaa
    29641 aaagtcattc aaagaaggga caaagttagc agtaatattc ctttttctaa gtggcttgag
    29701 tagtttggaa aacggcctga caccaaactg tcacggttaa tagtagtcat ctattaaagt
    29761 taatttaaaa gctattttta tctttaatgt tacataaaaa caattatgta acattaaagg
    29821 ttatctaaag catttttttg ctcatcattg acaatatggg tataaagatc cgtgacttga
    29881 gtagaggaat ggcctaattg atgactaact aacacctgag atttagtagc atcatatagt
    29941 cttgtcgcta gcgtatgacg caatttgtga ggagtcacac gaattttaaa atcctcagag
    30001 tacttgccaa ccatcttttc tatactagaa gcatccattc gatttggaac gccacggtat
    30061 tctgttaaaa agaaagcaag atcctgtttt tcagccttgt aacgtctctg acgaacagct
    30121 aaataagact ccaaataacc tttcgcaaaa cctgctacat tgactgaatc acgttttccg
    30181 cctttgcgaa taacttcgat aatcatcata tttagattga catcttttaa atcaagattc
    30241 actgcttcag acaaacgaac accagaagca agtagtagag caataatagc caaatccctc
    30301 tccttatttt tacggaaaga agatttggca cgattagaca atttttgctc atattcctta
    30361 tccacataat ccaagaaagc tagagtttca tcacctaaaa acagtttctg cttaatattt
    30421 tccgctctgg aggccagggt ttcttttttc ttttttgttg acactttttt cataacattc
    30481 cgataaaaat aaggctcccc ttggtcattt tcaacctctt cagtcaagta cttgtaaagg
    30541 cttgataagg cagacaaggt ccgattaata gtggtttgag aaagcccctc tttggtggaa
    30601 taggtgttga gagaaggtcg ttcccgcaaa taaagcacaa aggcctctaa atccttcttg
    30661 gtaaggtgct caagcgtgct caagtcaata tcagcaatct ttggcgcctg cgttaaatca
    30721 gcatccatca gccaatcaaa aaagcgtttg tattctttta aatactcata taaggtggta
    30781 aagctgtatg gaacagctaa tttggattgg taataatcta aaacatacca aggcatgaca
    30841 gccttgtagg tttcaatttt ttctagtaat aattcgcgtc tcatatcatc ataattcctt
    30901 aacaataaca attttttcaa aaatgaattt tcgcaaattg tctcatgtat tttatgccat
    30961 tcattctcta caagagcagt atatcacacc tataaatatt tttcaagaaa attacagttt
    31021 ttcggaaaga tgtcacgaga caaatctctt tttttacaga tactaacgtc acttctttta
    31081 gattcagtaa taatttacta tcattatttt agtaacttca ggcacagaat ttgtttagct
    31141 cagaactaaa tgataatttt atctttaaag taattaactc tttattagat atagacctgc
    31201 tagtacacga atctagtcgc tatgttttag gtgtttcccc tttttgacag tattgctatc
    31261 acatgaatta attgtaggaa atgttacact tgctttcgtt ttattttttt gatactatta
    31321 gtaaagttat aactttacta aaggagctac caaatgtttt ctggacatca actaaaaaca
    31381 gcacgattat caaagggaat aactcaatca gaattgggaa gattgttgca tgtcaataaa
    31441 atgacaatat ctaattggga aaaaggtaag aatataccaa atgaaaaaca tttaaatgcc
    31501 ttattgcatc tattcaatgt gacatctgat tatttcgacc caaactatag attgctaacg
    31561 ccttataacc agctgacaat atctaataaa gaaaaagtaa ttggctattc agagcgattg
    31621 ttaaatcatc aaatagacaa aaaatctaaa gatctcatag ataaaccatc acaattatat
    31681 gcttatcggg tctatgaaag tttatctgct ggtactggtt actcctattt tggtgatggt
    31741 aactttgatg ttgtctttta cgatgaacaa ttagaatacg attttgcgtc ttgggttttt
    31801 ggagattcta tggagccaac ttatttaaat ggcgaagttg ttcttataaa acaaaatagt
    31861 tttgattacg atggagcaat ttatgcagtc gaatgggatg ggcaaacata tatcaaaaag
    31921 gtatttcgtg aagatgaggg attacgtcta gtgtccttaa ataaaaaata ttctgataag
    31981 tttgctccct atagcgaaga acctcgcatt attggcaaaa ttatcgctaa ttttaggccc
    32041 ttagaaattt aagttagatt gattaggtta tttcaaattt taaatgaact catcatgcat
    32101 gtaacgcggt cttccataat tttaataatc ttgtatacaa gataaatgaa tttcacatca
    32161 aaaagagacg aaaatttccg tctcttttat tttcgttttt tctttgcttt ttttagtttg
    32221 ttagcttgac gtttcatggc ctgtttcatg gcaaattgtc caattttccc cttgaaccct
    32281 ttaccaaata cttgactcat atccatatca ccaccaaggc cagataaatc gggcatacca
    32341 ccttgtccca tcatcccttc taaggaagac atatctggca taccagcagg catgttttta
    32401 ggaagattat tgggattaat gcccatatct ttcatcatct tagacatatc gcccgacata
    32461 accccttgca tcatgctttt ggcttggtta aagtctttga taaatttatt aacttccaca
    32521 aagctgttcc cggaaccagc tgcaatacga cggcgacgac tcgggtttag taagtcaggg
    32581 ttttcacgtt cagcgggggt catcgaagag acaatagcac gtttgcgagc aatttggttt
    32641 tcgtcaactt tgatattggc caaagctggg ttaccagcca ttcctggaat cattttcaag
    32701 aggtcttcca taggccccat attttgcact tgatctaact gttcaatgaa atcattgaaa
    32761 tcaaaggtgt tctcacgcat tttttcagct aactctaagg attttttctc atcatattcc
    32821 tggctagctt tttcaataag agtgagtaag tcacccattc ccaaaatccg actggacatg
    32881 cggtctgggt gaaatgtttc aatatctgtg attttttcac caatacctgt aaatttaatt
    32941 ggttttccag tgatttcacg gacagatagt gctgcacctc cacgggtatc accatcaatc
    33001 tttgttaaca caactcctgt gatgctcaac tgatgattaa actcgtaggc tacattggca
    33061 gcttcttgac caatcatgct atctacaacc aaaagaattt catttggttg tgctaaagcc
    33121 ttgacatcgc gcagctcttc catcagtttt tcatcaattt gcaagcgacc cgcagtatca
    33181 atcaagacat agtcattgcg gttttcacga gcttgttcca aaccttttct gacaatatcg
    33241 actgctgagt ggtctgtccc catatcaaaa acaggtacat tgatttgttg ccccagtgtt
    33301 tttaactgat caatggccgc tggacggtaa atatcggcag caatcatcag tggtcgcgcg
    33361 ttttcttctt taattaattt attagcgagt tttcctgcaa aagtggtttt accagcccct
    33421 tgcaaaccga ccatcatgat aatagttgga atttttggag atttatcaat ctccgcggtt
    33481 tctgagccta aaatactcgt taattcttca ttaacaatct taagaatttg ttgtgttgga
    33541 tcaagagtat caataatctc atggccaata gcgcgctcac gtacgcgctt aataaaggtt
    33601 ttaacaactg gtaaagcgac atcggcttct aaaagagcta gacgaatctc ttttgtcact
    33661 tcttgaacat ctgattctga taatttcttt ttaccgcgaa tgtgtttaaa cacatcttgc
    33721 aaacgttggg ttaagctttc aaaagccata gtcaaaactc ctcttactct ctattgtcaa
    33781 tactggttag aatggaaatt ttttcttgca aatactcatc atgagggtag tgagcaatca
    33841 tgtcgtcaaa gatttcactt cgaacaacat aatccgaata catatgaagt ttcatctcat
    33901 aagtctctaa aattttttcc gtacgcttaa tattatcata gacagcctga cgactgacac
    33961 caaattcatc agcaatctca gctaagctat aatcatcggc ataatacagc tcaatataat
    34021 tcatttgttt atctgttagc aaagctgcat aaaattcaaa aagggcattc atcctgtttg
    34081 ttttttcaat ttccataatg ttcattttat catactatga ttgtttttaa cagtagcaaa
    34141 ttaattgcct tatgctgttc gtgtaaaaaa ggaagtcata aatgacttct ttactaatta
    34201 ttttctaagt aaaattcaaa acggtcaccg atatactgac tgcggacata ctcaaaaggt
    34261 ttgccgtctg taaagtaaga cacctgagtt agagccaaaa tggcatgtcc tttagcaact
    34321 tccaagtagg aggctacacg ctcacttgct agcttagcgt agattgtctg tttactttta
    34381 ccaatctcgt aaccatttgc tatcaatgag tgaaaaaagt gttctgtaat atcagctcgt
    34441 ttaaccgttt ttataaattt ttctgggatt gaagcaattt cgtacaccaa agggacactg
    34501 tctgcatagc ggatacgttc cattcgaatg accaagtctg ttttgtctaa gttcaattct
    34561 ttaacttcgg tatcactagc taattgcttt tgataggata ataatttaga ggagggttgt
    34621 cgtccttggg agcgtataat ttctgtgaaa cttgttgttc ctcgcatttt ttcttgaaca
    34681 cgatgactgg caacataagt accacttcct atccgccttt caagaatccc ttcttctact
    34741 agtaatgtaa tagcctgccg tagagtcatt cgactaacgg tgaaatgttc cgctaaatgt
    34801 cgttcacttg gtaagcgact accaattggc cagatgccca gatcaatgtc ttttttaatt
    34861 gcatcatgaa tttttatata agctggtaac atgccacact cctcaagtcg gttattcatc
    34921 tattttatca tatttttgat gaaaattgaa ttgtaaatat tgaggtattt ggcatcaatt
    34981 aatgatatta cctgcgacaa taactggtga atttggtgga aaatgaatag gttccataaa
    35041 ccaactagtg agcttcgctt tagtaacaat ggatgaggta aaaacattat ttaaaaccct
    35101 aataactcct acttttgagg aatgctgacc aatagaacca ctataggctc tcaggcaacc
    35161 agtcggatct atataaggta aaaattgatt ttggcttaca gtaatattgt gacatagatg
    35221 tcgagtttgg ttaaatgctt catagtttgg agcaatatta ctaagtagac ctccatccca
    35281 tgcaaaatga tgaacagcag catcaaactg aatgacttct gaaaaaaaat catgcccttg
    35341 agcctttgat agcagctgtt ggtcttgtac taattctggc gcatagccaa taaattggtt
    35401 tttctcaaac aatgaatttt gtagagatcc taaatcaaaa atatgactat tacgcttatg
    35461 aaccatagta aatttgttat cgtaaatatg ccaatcagta ccatgatcag ccataatcat
    35521 aaagtggtct ccttttttca aatcatttgc tttgaaatgc actccagtca acacgagatt
    35581 acgaacacct tgttcagcct ttggtcctgt agggaatcca aaccacaaca ttttaccgtg
    35641 aataatgaac tctgtctgat gaccaataat agctgtatca gatggaagct caaaataatc
    35701 tttttgtgaa ggcaaagagc caatgtgaaa ttgccccttt ggaaaagata taacgctatt
    35761 tggatgctgc tttgcataag cgaaagcttt tcgcaaaaga cgattgtttt gctcagggga
    35821 atttccttta ttgaacctaa tataataagg tttaacaaaa tcttgctctg aaattccatc
    35881 taatcttaga ttatctttca ggttaatatc gtactgatat cctcctaacg aatagtcata
    35941 gcgtttttta acttgtttaa tagtcgctaa ttgaccttga tacactttta tatgtggctt
    36001 tttagttaat gaagataatt taacgatatc tcctttttta aacctcggtt tatcaggctc
    36061 tttcaggtta tgttctggca aagaaacagt gacttttcct attggaaata ccacttcata
    36121 atgataactc actcggtaat tttcggctat atcttctacc tgtttattaa tagttccaat
    36181 ccattgatga tatggaccac ttttttgtac ttgaatagct tgtccaatgt gatagcgagg
    36241 ctgttgatct ttgcttcgtt ccactattcc gacagttgct aatatattgt gaagtgttgc
    36301 aaaactattg gtccacgcaa ggtacgaaac aactaaactc aacaataatc ctaggaaaat
    36361 taattcaaca ggtcgaaata aacccaaaat tctctttttt cttagcatag gccctccctg
    36421 ttgtcttaat tccctttcat agcctctatt gtaacataac gattacgttt ttttccaacg
    36481 agctagagaa attgtaatgt cttttcgatg aaaatatgct acaataagtt gacaactatc
    36541 agcctgacgg ttggtataga atgaaaggat tataatgact gaaatttcaa ttttgaatga
    36601 tgttcaaaaa attatcgttc ttgattatgg tagccagtac aatcagctta ttgctagacg
    36661 tattcgagag tttggtgttt tctccgaact aaaaagccat aaaatcaccg ctcaagaact
    36721 tcgtgagatc aatcccatag gtatcgtttt atcaggaggg cctaactctg tttacgctga
    36781 taacgccttt ggcattgacc ctgaaatctt tgaactaggg attccgattc ttggtatctg
    36841 ttacggtatg caattaatca cccataaatt aggtggtaaa gttgttcctg ctggacaagc
    36901 tggtaatcgt gaatacggtc agtcaaccct tcatcttcgt gaaacgtcaa aattattttc
    36961 aggcacacct caagaacaac tcgttttgat gagccatggt gatgctgtta ctgaaattcc
    37021 agaaggtttc caccttgttg gagactcaaa tgactgtccc tatgcagcta ttgaaaatac
    37081 tgagaaaaac ctttacggta ttcagttcca cccagaagtg agacactctg tttatggaaa
    37141 tgacattctt aaaaactttg ctatatcaat ttgtggcgcg cgtggtgatt ggtcaatgga
    37201 taattttatt gacatggaaa ttgctaaaat tcgtgaaact gtaggcgatc gtaaagttct
    37261 tctaggtctt tctggtggag ttgattcttc agttgttggt gttctacttc aaaaagctat
    37321 cggtgaccaa ttaacttgta ttttcgttga tcacggtctt cttcgtaaag acgagggcga
    37381 tcaagttatg ggaatgcttg ggggcaaatt tggcctaaat attatccgtg tggatgcttc
    37441 aaaacgtttc ttagaccttc ttgcagacgt tgaagatcct gagaaaaaac gtaaaattat
    37501 tggtaatgaa tttgtctatg tttttgatga tgaagccagc aaattaaaag gtgttgactt
    37561 ccttgcccaa ggaacacttt atactgatat cattgagtca ggaacagaaa ctgctcaaac
    37621 catcaaatca catcacaatg tgggtggtct ccccgaagac atgcagtttg aattgattga
    37681 gcccttaaac actcttttca aagatgaagt tcgagcgctt ggaatcgctc ttggaatgcc
    37741 tgaagaaatt gtttggcgcc aaccatttcc aggtcctgga cttgctatcc gtgtcatggg
    37801 agcaattact gaagaaaaac ttgaaaccgt tcgcgaatca gacgctatcc ttcgtgaaga
    37861 aattgctaag gctggacttg atcgtgacgt gtggcaatac tttacagtta acacaggtgt
    37921 ccgttctgta ggcgtcatgg gagatggtcg tacttatgat tataccatcg ccattcgtgc
    37981 tattacgtct attgatggta tgacagctga ctttgctcaa cttccttggg atgtcttgaa
    38041 aaaaatctca acacgtatcg taaatgaagt tgaccacgtt aaccgtatcg tctacgacat
    38101 cacaagtaaa ccacccgcaa cagttgaatg ggaataacag aataaacatt aaaagactcg
    38161 ctcattttgg cgagtctttt aatgtttatt ctttaactgt tttcgtattt tgtacatggt
    38221 attagcaata tgataaagtg ggctgacagg gagattaaat tctcctataa attcttctat
    38281 tgtcggagca aagttggcct taaatttggt aagtccatca tcaagcgagc cttctactcc
    38341 tcccatgtta gcccaaataa taccatcttg ataagcatcc tgaaaaactt taggatacag
    38401 cagatactga ggataaaact tcttaaaatc atcattcatc ccagcataaa gcatttccat
    38461 aacatttcca taagaaatag ataatatacc tgctacaaca acttcctcag gatattggtc
    38521 tgtaaagcct tcaaattcag ttatataacg ttcaaaagaa gctttttgat cttctaattt
    38581 ttttaaacgc ttcttttgat gagcttgggt gcgagtaata tcttggttaa taagatttaa
    38641 ttgctggcgg tattgatcta gtttttgagg aatattcact tttgctagat gtaagtaggc
    38701 cttatcccca taagtagtca tcaacttttg aaagtaagct tcgttacgca aagaaatatt
    38761 tttacgtttt tctgttaagg agacaatctt ggaaaatttg tgaagttctg attgactggc
    38821 acgatatgtt tctacaccac gctgcttagc atcttttatt aaacgtctgg tatgcttagg
    38881 aaattgcatc tcaaggtttt cttgagtgta aatattagct tggaaacgag gttggatact
    38941 atctgcaatc tccattgtta aaccagtcca atgaacacca gcttcttgga gattcttaat
    39001 agctgctaaa gctaaaggtt tttcttcttc ttcctgtccc agtgcgtatt gttttaacag
    39061 gatagctgga tcatatttga taaagagggc ctttttagtt ttaccataat cctttagtgt
    39121 tttcatggta aatgccacca aatcacggtc aagataatcc atgactggcc ctcttggaat
    39181 ataaataatg cttcttccaa gtggcaatag cttaatcaaa agtgataaag aggcaacctg
    39241 cttttcctct ttatagatac caattcgctc attctgccat tgatttttga tttttgccca
    39301 atcactacct tgtaaaacgc taatttgctg atgttcttta acaaaagagt catgctcttc
    39361 ttctgaaata ccgatttttg cataaaacgt taaattcgtc atttattgtc cccatctatt
    39421 cgtaatctta gcagatgtac ttactaagta tcttcactgt ctttatctat ttattcgtaa
    39481 taaattttaa aaaaacataa aaaaataggg aaactatttg aatcactttt tagtaataac
    39541 gtttgtatct taaatgactt gttaatcacc aacaatttca tgaacaactg atcatcaaaa
    39601 aataagctat tattaaacga ctttacacca ttccattaga taaaaaaaag atgtagtcac
    39661 atcttttttg gttggtgatc agttacctaa accatcacat atctagcagt atttattcta
    39721 tatctttact gattttagta attcctgtgt aaaaaattaa ggaatagttt aggttaactt
    39781 actaaaatcc caagtatcgg ttacccaccc attgtagaaa tcaggttcat gacaaaccat
    39841 taaaatagaa cccttatatg cttttaaagc acgtttgagc tcatttttag catcaatatc
    39901 aagatgattt gttggttcgt ctaaaataag cacgttattt tcacgattca tcaacaaaca
    39961 aaaacgaact tttgcttgtt caccacccga aagtacttga atttgacttt caatatgttt
    40021 tgatgttagt ccgcaacgag ctagtgccgc tcgaacttct gcctgattta aggcaggaaa
    40081 agcatcccaa actacttcta gcggagtttg tcggttaaca cctgtcactt cttgttcaaa
    40141 gtagccaact tctaaaaaat cccctgtgac aatatgacct tctaaaggct cgataacacc
    40201 taataaactt tttagcaaag tagattttcc aataccgttg gccccaacaa tagcaatttt
    40261 ttggtttctt tcaaacgtta tatttaaggg ttctttggtc aatgggtaat cataaccaat
    40321 cacaagattt tttgtttgaa aaatgaatcg actgggagtt ctagcttgct taaattcaaa
    40381 atttggtttt ggtttctcag cttgaagttc aattatatcc atcttatcaa gttttttttg
    40441 gcgagacatt gccatgttac gtgtcgctac ccgagcctta tttcggttga caaaatcctg
    40501 caagttagca atctcttttt gttgacgttc ataggctgct tcaagttgag attgtttcat
    40561 ctcataaaca gcttgaaatt ggtaataatc cccagtatag cgaactaaac tttgattttc
    40621 aacatggtaa acaatattaa tcacatcatt taagaaagaa atatcatgcg aaatcaacac
    40681 aaaagcattt tcataatgtt gtaaatagcg ttttaaccat tcaatatgct cagcatccaa
    40741 atggttagtt ggttcatcta atagcagaat atcaggtttt tctaatagta atttggctaa
    40801 taaaaccttt gttcgttgcc cacctgataa ggatgtaaca tctgactcca ttccaaaatc
    40861 cataacacca agcgcacgcg ctacttcatc aatcttagca tccaaagtat agaaatcacg
    40921 actttctaaa cgatcttgaa gctcacctac ttcttccatc aaaacagcaa tatcagcttt
    40981 atcatctgcc attgacgcgt aaatctcatt aatacgattc tcggtcttaa ataactcatc
    41041 aaaagcagtt cgcaagacat cacgaacggt ttgtcctgat tccaacactg tatgttgatc
    41101 caggtaacct gcagtgacat acttcgacca ctctactttt ccttcatcag gctgtaaatg
    41161 tcctgtgact atactcataa aggttgattt tccttcacca tttgctccaa ctagtccaat
    41221 atgttcacct tttaagaggc gaaatgacac attttcaaaa atagcccgat ccccaaaacc
    41281 gtgactcaac tgcttaactt ctaaaatact catcgtttct tccttaactg tcatcaaaaa
    41341 agccgtcaaa acggctttat agttatttca ttatggcaaa attgtaacct tttgtcaata
    41401 tttgactgaa agtgtacctt gcttttttat cgataaggta cttgtatcaa aaacctcttt
    41461 ttgcttgtcc gattgtaacc ttttctttta agtttttgat aacaggatac aaaagaggaa
    41521 cagcaactaa agtcacaaaa gatgttccga aactaccacc aatttttcca agagctaccc
    41581 aaaaagatac cgaaagtggt agctgagtac ctatataagc taacagtaag tattttataa
    41641 ggttaatagt taattttgac aatgcagcaa taactgttat tgttataatg gcttttggtt
    41701 ttttactaga ttgcatagct ctttcatata ccaaatgcaa aattaaacaa atagccaagg
    41761 attctaagat agttatccaa acgactgaag catagccgtt caaaacatca aagatcccta
    41821 aaccaagact agcaactaga gctccttttt tactaccata gatcaagact gcaataacaa
    41881 ctaatgcatt gccaagatga ataaactgca taccgatagg gatacgcaac acttgtactg
    41941 aaataaaaat taaagcggca tacatactca attcaatata attagctaat ttttgagatg
    42001 acattttttt cctccaacaa ctttttaaac gatttagtta agtaatttaa atgagattca
    42061 taagcaacac ctaagattaa atctcttttt aatgtaaggg tattttgcaa tactttttca
    42121 agaaatgaaa caacaagatc tagaatttgt gttagtggta gctgataata gaatcctgct
    42181 gttataatag ctgatgctat atctcctgta ccatagaaat ggtaagggaa ttgcttccca
    42241 aaatggaatg ttaattgatc tgaatctgac tgatagtaag caaaaccaat gctgccctcc
    42301 tcaaaagaga ttccgctaat gacaacctgt ttaggtccaa gcttagctaa ttttctagcc
    42361 acctgtctaa tatcttcttc atcataattt tttgctaaat aagctgtttg tgttaataga
    42421 caagcctcac taatattagg taaaacaagc tcagcttttt gagtaagttt tatcataatc
    42481 tctatatgtt tttgactgaa gccttgataa agttttccat tatctgccat aattggatct
    42541 aaaattaagg gaagttgctt tcttgaaagc cattctagta gcttttgccc atctcttgtt
    42601 gtcgtaaaat aacctataaa gatgccgtca aacttaattc ttttgttgtc ccaatctgtt
    42661 aaaaaaacgt ctaatatact tgatgtagta tgcttcacag ggctctgtcc tccgccagta
    42721 tggcttgata aaaggcaagt tggtaataaa acttgctcta acaaacaaga agccattaaa
    42781 ggaatactag cagacaaagc taccttacca acaccaacca gatcatttgc cacaataatc
    42841 cgtttcatag ctattacctc ttttctataa taactattgt aagaaaaaga ggcataagat
    42901 acaatagtta taacacttaa ctgtatgggg acaatttatg acaacaaaat atcaaacaat
    42961 catttccaat atcgaacaag atatccagaa acagcgacta aaaaaagggg acaagctacc
    43021 ttcaattagg gtattaagta aggtttatca ttgtagcaaa gatactgttc agcgggctct
    43081 tttagaatta aaatatcgtc acttaattta tgctgttcct aaaagtggtt attatgtttt
    43141 gggtaacgta agcatgcccg ataatgttct taatctaagt cttgaagatt ataataatat
    43201 ggcttatgaa gatttccgac tctgcttaaa tgaggcttta agtgctaaag acaaatacct
    43261 ctttcattat tatcacaaaa ccgaaggact agaagaacta agggaagctt tgcttcttta
    43321 cttagctgaa aatagtgttt acagtaacaa agaccaacta ttaatcacct ctgggacgca
    43381 acaagcgctt tatattttat cacaaatgcc ttttcctaat gcgggcaaaa caattctcct
    43441 tgaaaagcct acttatcatc ggatggaagc tattgttgct cagttaggat taccctatca
    43501 aactatctct agacacttta atggccttga tttagaactc ttagaatctt tatttcaaac
    43561 tggcgatatt aaattttttt acacgatttc acgattttca catcctctgg gactttctta
    43621 taacactaag gaaaaggaag ctattgttcg tctagcacaa cgataccagg tttatatttt
    43681 agaagatgat tatttaggag attttgtgaa acttaaagag ccaccaattc attattatga
    43741 cactcatcac cgaatcatct acctaaaatc tttttcaatg agtgtttttc ctgcactccg
    43801 tatcggagct ctagttttac cgtcaggttt aaaaccttat tttttaaccc aaaaatcact
    43861 gattgattta gacacgaact tactaatgca aaaagcatta gctctttatt tagaaaatgg
    43921 gatgtttcaa aaaaatcttc gctttattaa gcgttatcta aaacagcggg aacgtcaatt
    43981 ggctctcttt ttaaaacaaa attgccctga tattcactat caactaaccc ctactcattt
    44041 agtgattgat tacacgacat cagactctta tagaaacttt acattagata aatctgatag
    44101 aataataata actggaaaaa agcgctatct ctctattgct atcaatcaac aaatacaaag
    44161 caaattaaac tcgctaatca aaaatacttg tggaaagagc aactaacttt tcttcgtacc
    44221 attaatataa aaaatg
//
LOCUS       DATWEK010000013        41021 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.013, whole genome shotgun sequence.
ACCESSION   DATWEK010000013 DATWEK010000000
VERSION     DATWEK010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41021
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.013"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..338)
                     /locus_tag="VCR92_000855"
     CDS             complement(<1..338)
                     /locus_tag="VCR92_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEP4267938.1"
                     /translation="MLVLYVSSKLIKRRRMKFMYSALLGNPVEHSISDELFEYLNHNI
                     GVLDEYKHKKILVDSVCLEDKIKHLINDPKCIGLNITLPYKREVMRYIDNLDRVAEIT
                     GSINNIYKSG"
     gene            complement(407..478)
                     /gene="shp3"
                     /locus_tag="VCR92_000856"
     CDS             complement(407..478)
                     /gene="shp3"
                     /locus_tag="VCR92_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP3"
                     /protein_id="HEP4267939.1"
                     /translation="MKKISKFLPILILAMDIIIIVGG"
     gene            558..1409
                     /gene="rgg3"
                     /locus_tag="VCR92_000857"
     CDS             558..1409
                     /gene="rgg3"
                     /locus_tag="VCR92_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Regulator gene of glucosyltransferase 3; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg3"
                     /protein_id="HEP4267940.1"
                     /translation="MKSKLGATLRKVRKGKQISLCFVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDEDYTNSETFANLVQYIRKQYSSQNINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSSIIPSDDELLQLTDYLFKVEKWGYYEILLLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSRNKTNKRIVTQLAINCFILSINKEEFSNCSYLIDEIK
                     SLLDNELNFYEQTVFLYATGYFEFKRQLETGVEKMKQAIQVLDILNEDKLKLHYADHF
                     DKLVNKD"
     gene            complement(1662..5201)
                     /gene="smc"
                     /locus_tag="VCR92_000858"
     CDS             complement(1662..5201)
                     /gene="smc"
                     /locus_tag="VCR92_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEP4267941.1"
                     /translation="MFLKEIELEGFKSFADKTKIEFYKGVTAVVGPNGSGKSNITESL
                     RWALGESSAKNLRGGKMPDVIFAGTQNRNPLNYAKVAVVLDNSDHFIKTAKKEIRVER
                     HIYRNGDSDYLIDGRKVRLRDIHDLFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQIKLNQTQDNLDRLEDIIYELDTQLAPLEKQAKVAKQFLEL
                     DANRKQLQLDILVKDIDIAQERQTKDTEALAALQQDLASYYAKRQSMEEDYQKFKQKK
                     QVLSQESDQTQTTLLELTKLIADLEKQIELVKLESGQEAEKKAEAKKHLEQLQEQLDG
                     FQAEEKQRTEQLLHIDQQLCDVKQQLNELSNALERFSSDPDQLMETLREEFVLLMQKE
                     AALSNQLTALKAHLDKEKQARQHKAQEYQLLVTKLDQLNDESQKAQAHYKAQKEQVEM
                     LLQNYQEGDKRVQELERDYQLKQERLFDLLNQKKGKEARKASLESIQKSHSQFYAGVR
                     AVLQSQKKLGGIIGAVSEHLSFDSDYQTALEIALGANSQHIIVTDEAAAKRAIAYLKK
                     NRQGRATFLPLTTIKARSLSEHYHRQLATCEGYLGTAESLVRYDDSLSAIIQNLLSST
                     AIFETIDQANIAARLLGYKVRIVTLDGTELRPGGSFSGGTNRQSNTTFIKPELEQISE
                     ELTRLVEQLKITEKEVAALQSDLIAKKEELTQLKLAGDQARLAEQRAQMAYQQLQEKQ
                     EDSKALLAALDQSQTTHSDESLLAEQARIEEALTAIAKKKSALTCDIDDIKENKDLVR
                     QKTQNIHQALSQARLQERDLLNEKKFEQANQSRLRTQLKQCQQNILKLESILNNNVSQ
                     DSIQRLPQWQKQLQDATEHKSGAQKRLVQLRFEIEDYEARLEETAEKITKESEKNDTF
                     IRRQTKLETHLEQVANRLRAYAKSLSEDFQMTLADAKEVTNSIDHLESAKEKLHHLQK
                     TIRALGPINSDAINQYEEVHERLTFLTSQKTDLTKAKNLLLETINSMDSEVKARFKVT
                     FEAIRKSFKETFTQMFGGGSADLVLTETDLLSAGIEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFAIIRVKTIPFVILDEVEAALDEANVKRFGDFLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGITMQESGVSKIVSVKLKEAQEMTN"
     gene            complement(5202..5894)
                     /locus_tag="VCR92_000859"
     CDS             complement(5202..5894)
                     /locus_tag="VCR92_000859"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEP4267942.1"
                     /translation="MKQLEELLSTSFDIQFNDLTLLETAFTHTSYANEHRLLNVSHNE
                     RLEFLGDAVLQLIISEYLFAKYPKKTEGDMSKLRSMIVREESLAGFSRFCSFDAYIKL
                     GKGEEKSGGRRRDTILGDLFEAFLGALLLDKGIDAVRRFLKQVMIPQVEKGNFERVRD
                     YKTCLQEFLQTKGDVAIDYQVISEKGPAHAKQFEVSIVVNGAVLSKGLGKSKKLAEQD
                     AAKNALAQLSEV"
     gene            complement(6327..7136)
                     /locus_tag="VCR92_000860"
     CDS             complement(6327..7136)
                     /locus_tag="VCR92_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEP4267943.1"
                     /translation="MNESGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRKPEDLDAILITHEHSDHIKGVGVMARKYHLDIYANEKTWQLMDECNMLGKLDA
                     SQKHIFQRDKVLTFGDVDIESFGVSHDAIDPQFYRIMKDNKSFVMLTDTGYVSDRMTG
                     IIENADGYLIESNHDIEILRSGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGYNTKK
                     IYLGHLSKENNIKELAHMTMVNQLAMADLAVGTDFTVHDTSPDTACPLTDI"
     gene            complement(7140..8492)
                     /gene="vicK"
                     /locus_tag="VCR92_000861"
     CDS             complement(7140..8492)
                     /gene="vicK"
                     /locus_tag="VCR92_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEP4267944.1"
                     /translation="MTRDIIGNLSTFELAILILLVFVAFYFIHLAVRDYRNARIIRMM
                     SHKIRDLINGRYTDIIDEKADIELMELSDQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MSDGVLATDRSGKIIMINETARKQLNLSKEEALKKNITDLLEGDTSYTYRDLVSKTPV
                     VTVNSRNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVT
                     QLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVYEIVRDYPITSVWIEIDNDKMTQVI
                     ENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKTDLPLIFDRFYRVDKAR
                     SRAQGGTGLGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDVD
                     "
     gene            complement(8485..9195)
                     /locus_tag="VCR92_000862"
     CDS             complement(8485..9195)
                     /locus_tag="VCR92_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP4267945.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
                     LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSR
                     PEYILTRRGVGYYMKSYD"
     gene            complement(9357..10391)
                     /locus_tag="VCR92_000863"
     CDS             complement(9357..10391)
                     /locus_tag="VCR92_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEP4267946.1"
                     /translation="MCYNMVKKDEEKAMKQAILDRYQALKCYQNAGLSNQAFRAIAKE
                     PIIDNRLGSPTFWVIWPIEKENQSAKQLLTFLLDLVEMPFELSGQLHETQTLLTRFHP
                     SLLPDHMFWKELASLVDQAFPGKTLSQAGELEKRLHQFRYVISSQQAQSIRNHYKMIE
                     MTDAQALALFLRSKKGPCLWRQAPDYTLMDSARLHNKLRFEDNKVIFPSQEVSYNIKV
                     LLWFHTEFILDSTGFFLNEVDAEVVTEKGIVNGASFNYGTDGPRHWDLDVDPISRHDP
                     QFRRDTLKGFRSPKRVFRQWFRAQKDDFMFSYFNAKGLFAYHNKSSFARVKKSAKQFK
                     RQIHPIKGWF"
     gene            complement(10447..11694)
                     /locus_tag="VCR92_000864"
     CDS             complement(10447..11694)
                     /locus_tag="VCR92_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEP4267947.1"
                     /translation="MLTKLEYWAKQCPNKKAIVADQISLTYQELWQAVLIKDQTIKDS
                     VPYIISHSRYLNQLLSFLRGLKEGSCPIILHPNISGTFQQQIKHVDSELLKKADFAVL
                     SSGTTGKAKLFWRCLSTWTRLFDYQNKVFGMTGNSCLFLHGSFSFTGNLNLALAQLWA
                     GGCLVLSQKLSLKTWLSLWQAKKVSHLYLLPTYLNRLLPYLTKNNMTATHLLTSSQMI
                     SQELLRHYYKKFPQLEIVIFYGASELSFITWCNGRAAVKINGLVGQPFPDVSISFKDK
                     EIFVETPYSVEGMSQPYSVSDLGKMSPAGLILEGRQDDWVNQRGVKCHLPSLVELAHQ
                     APNVKEAHALKIGKGENETLILVLVLTKKDCLAPIKDFLALYLNSGQLPKYYLVIDCL
                     PLKDNGKINREVLLNKIPKQWLS"
     gene            complement(11651..12799)
                     /locus_tag="VCR92_000865"
     CDS             complement(11651..12799)
                     /locus_tag="VCR92_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEP4267948.1"
                     /translation="MTDVYIAAGLRTPIGLVGKQFAKEQPEILGAKLINALQNKYPVP
                     IDQVICGNAVGTGGNIGRLMTLYSHLGESVSALTVDMQCASAGAALSVGYAKIKAGMA
                     SNLLVGGIESSSLQPESVYASADWRQGAYKVAQFSPDSISPFAMIEGAERVAREHGFT
                     KEYLNHWTLRSHQKASYCQEQALLADLILDLPGASDQGIRPRLSSKVLSKVPPILGED
                     HVISAANACLTHDAAAFLQLSSQPSAFKLIDVVEVAGDPQRSPLMVIKASQVLLEKHG
                     LGMADMTAIEWNEAFAVIDGLFETHYPDLLDRYNIFGGALAYGHPYGASAAIIILHLM
                     RALEIKNGRYGIAAIAAAGGQGFAVLLKYHKEFSHADKARILGKAMPK"
     gene            complement(13194..13343)
                     /locus_tag="VCR92_000866"
     CDS             complement(13194..13343)
                     /locus_tag="VCR92_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase"
                     /protein_id="HEP4267949.1"
                     /translation="MQLLDNVYGTLRSFAFMRPVKSSNDTSLADALQADTDMAFILVR
                     GINYQ"
     gene            complement(13429..14214)
                     /locus_tag="VCR92_000867"
     CDS             complement(13429..14214)
                     /locus_tag="VCR92_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4267950.1"
                     /translation="MAKLRRMHAIFIKQYLKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     SVLFQHIPSLEGWTFEQIAFIYGFSLIPKGIDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PISPLFHVLVETFQVDALGELLVGVILLVTTAGSIVWTLPKVLLFILVIPFATLIYTS
                     LKIATASISFWTKQSGAVIYIFYMFNDFSKYPMSIYHSFLRWLISFVIPFAFTAYYPA
                     SYFLTGQHLLFNIGGLVVVSLLVLALSLKLWKWGLDAYESAGS"
     gene            complement(14216..15034)
                     /locus_tag="VCR92_000868"
     CDS             complement(14216..15034)
                     /locus_tag="VCR92_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEP4267951.1"
                     /translation="MWSFWKRYRPFLSAGIQELITYRVNFFLYRIGDVMGAFVAYYLW
                     KAVFDSSKQSLINGFTLSDMTFYIIMSFVTTLLTKSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFMEIGFRWIVLMSVGFPFLMVLSGIKVMAGLSTLQVLASSCLYLVSLLLA
                     FLINFYFNICFGFSAFVFKNLWGSNLLKNALVAFMSGSLIPLAFFPKVVYIVLSFLPF
                     SSLVYTPVMIVIGKYSLSQIMVALSLQIFWLLVMVVLSQVIWKKVQYHLTIQGG"
     gene            complement(15036..16028)
                     /locus_tag="VCR92_000869"
     CDS             complement(15036..16028)
                     /locus_tag="VCR92_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEP4267952.1"
                     /translation="MVMIEVSHLQKNFSKTIKEPGLKGALKSFVHPQREIFEAVKDLS
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGYCRINGKIPQDNRQDYVRDIGAV
                     FGQRTQLWWDLALQETYVVLKEIYDVPEKAFRKRMDFLNEVLDLNEFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEKTTILLTTHDLS
                     DIEQLCDRIIMIDKGQEIFDGTVTQLKQSFGKMKSLSFELKPGQEQVVSQFMGLPDIT
                     VERHELSLDIQYDSSRYQTADIIQKTMADFAVRDLKMTDVDIEDIVRRFYRKEL"
     gene            complement(16169..18112)
                     /gene="thrS"
                     /locus_tag="VCR92_000870"
     CDS             complement(16169..18112)
                     /gene="thrS"
                     /locus_tag="VCR92_000870"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEP4267953.1"
                     /translation="MIKITFPDGAVREFESGVTTFDIAESISKSLAKKALAGKFNDQL
                     IDTTRAIEEDGSIEIVTPDHKDAYEVLRHSAAHLFAQAAKRLFPNLHLGVGPAIAEGF
                     YYDTDNAEGQISNEDLPRIEAEMQKIVTENYPCIREEVTKEEALELFKDDPYKVELIN
                     EHAGAGLTVYRQGEFVDLCRGPHVPSTGRIQVFHLLNVAGAYWRGNSDNNMMQRIYGT
                     AWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPDGATIRRTLE
                     RYITDKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPVMDMGDGEEFVLRPMNC
                     PHHIQVYKNHVRSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHIFVTPEQ
                     IQEEFQRALQLIIDVYADFNLTDYRFRLSYRDPNDTRKYYDNDEMWENAQSMLKAALD
                     EMGVDYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFDLKYIGADGEE
                     HRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPHQVTVIPISNEAHIDYAWEVAKT
                     LRDRGVRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMEDKSVNVRRYGSKATHTE
                     SVEEFVENILADIARKSCPDAQA"
     gene            complement(18534..19868)
                     /locus_tag="VCR92_000871"
     CDS             complement(18534..19868)
                     /locus_tag="VCR92_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEP4267954.1"
                     /translation="MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRD
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTQTEFSLGLLGK
                     MIGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIPLEKYIRDDITAEEVTNLKAELGIAGDETMLLSLSRISY
                     EKNIQAIINQMPAILAENAKIKLIIVGDGPYLQDLKHLAMQLEVDKHVTFTGMVPHDK
                     VALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKMFGTLYYAE
                     TDLTDAIIDAILKTPVMDKRLLAKKRYEISAQHFGKSIYTFYLDTLIARNSKEAQKLS
                     LYLNHSGKSSSLKLVQGAIHLPKRAAKVTAITSVKVVKAPIKLVHAIKDFLD"
     gene            complement(19870..20868)
                     /locus_tag="VCR92_000872"
     CDS             complement(19870..20868)
                     /locus_tag="VCR92_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEP4267955.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQHFTTNPRETY
                     DLVHLNTYGLKSWLLMIKAQKAGKKVIMHGHSTEEDFRNSFIFSNLLSPWFKKYLCHF
                     YNKADAIITPTLYSKSLIESYGVKSPIFAVSNGIDLEQYGADSKKEAAFRRYFDIKEG
                     EKVVMGAGLFFLRKGIDDFVKVAQAMPDVRFIWFGETNKWVIPAQVRQMVNGNHPKNL
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYYGWVDQ
                     SSAELATDIPGFIEALKKVFSGASNKVEAGYKVAQSRRLETVGHALVDVYKKVMEL"
     gene            complement(20999..22000)
                     /gene="ccpA"
                     /locus_tag="VCR92_000873"
     CDS             complement(20999..22000)
                     /gene="ccpA"
                     /locus_tag="VCR92_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEP4267956.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
                     VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            22174..23259
                     /locus_tag="VCR92_000874"
     CDS             22174..23259
                     /locus_tag="VCR92_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEP4267957.1"
                     /translation="MTKLDQIRLYLDQKGAELAIFSDPVTINYLTGFFCDPHERQLFL
                     FVYHDLAPVLFVPALEVARASQAISFPVFGYVDSENPWEKIKAVLPNTAAKTIYVEFD
                     HLNVNKFHGLQTIFSGQFNNLTPYVQGMRLVKSADEINKMMIAGQFADKAVQVGFDNI
                     SLDATETDVIAQIEFEMKKQGIHKMSFDTMVLTGNNAANPHGIPGTNNIENNALLLFD
                     LGVETLGYTSDMTRTVAVGQPDQFKIDIYNLCLEAQLAAIDFIKPGVTAAQVDAAARQ
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMAGNDLVLEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKNGFEVFTHTPKELLYFEG"
     gene            23308..23973
                     /locus_tag="VCR92_000875"
     CDS             23308..23973
                     /locus_tag="VCR92_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEP4267958.1"
                     /translation="MDQTIHHQIQQALHFRTAVRVYKEEKISDEDLALILDAAWLSPS
                     SVGLEGWRFVVLDNKPIKEEIKPFAWGAQYQLETASHFILLIAEKHARYDSPAIKNSL
                     LRRGIKEGDGLNSRLKLYESFQKEDMDMADNPRALFDWTAKQTYIALGNMMMTAALLG
                     IDTCPIEGFHYDKVNHILAKHNVIDLEKEGIASMLSLGYRLRDPKHAQVRKPKEEVIS
                     VVK"
     gene            23984..24361
                     /locus_tag="VCR92_000876"
     CDS             23984..24361
                     /locus_tag="VCR92_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEP4267959.1"
                     /translation="MKALHTCIRVKDLDQSVAFYTSAFPFKENYRKDFPDSQFTLVYL
                     ALEGESYELELTYNYGHGDYDLGNGYGHIALGSEHFEADHKKHRQAGFPVTDIKELAD
                     KSARYYFIQDPDGYKIEVIDLNN"
     gene            24506..25432
                     /locus_tag="VCR92_000877"
     CDS             24506..25432
                     /locus_tag="VCR92_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEP4267960.1"
                     /translation="MTLLSIIVPCFNEEANILPYFEEMHQLETSMTNQLAFEYIFIDD
                     GSKDNTLGILRELAARFPNVHYLSFSRHFGKEAGLLAGLKEAKGNYITVMDVDLQDPP
                     ELLPVMYAKLKEGYDIVGTRRQNRQGEPLIRSMCSNLFYGLIKHLSDTEMVNGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYRITYLSFENQKRKYGKSRWHFWELLRYSL
                     DGFINFSEMPLTIATWTGTFSFLISIFAILFIIIRKILFGDPVSGWASTVSIILFMGG
                     IQLFCMGIIGKYISKIFLETKKRPLYIIKEKH"
     gene            25643..26326
                     /locus_tag="VCR92_000878"
     CDS             25643..26326
                     /locus_tag="VCR92_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEP4267961.1"
                     /translation="MEWIKLIGIVIIVLGFILKFDAIATVVVAGLVTALVSGISFIDF
                     LDILGKEFTNQRLLTIFFITLPLIGLSETYGLKHRATQLIQRVQALTVGRLLTLYLII
                     RELAGLFSIRLGGHPQFVRPLIQPMGEAAAKANIGEELTDAEKDDIKAMAAANENFGN
                     FFAQNTFVGAGGVLLIAGTLEQLGYDGNQAKIAFSSILIAIISIIIVAIYNYLFEKKM
                     ERQHQKGDN"
     gene            26326..27252
                     /locus_tag="VCR92_000879"
     CDS             26326..27252
                     /locus_tag="VCR92_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEP4267962.1"
                     /translation="MANIANLVLETIYILIGLQLFHTAYCTFKDKTNPVYFGTALFWG
                     LLGVTFVGGAFLPNKVIGFIVIVLALLTLFKQVRIGTLPAFNEQKAEESAHRIGNWIF
                     LPVMLMAMISLLLALILPDFSKSAIGIAGILATIAILIITKQKPSALLAENNRMNQQV
                     STSGILPQLLGALGAIFAAAGVGDVIASLIREIVPADSRFFGVLAYVLGMVIFTMIMG
                     NAFAAFTVITTGIGVPFVFALGADPIIAGALAMTAGFCGTLLTPMAANFNALPVALME
                     IKDRNAVIKKQAPIALVLIISHIALMYLLAYY"
     gene            27302..27949
                     /gene="pcp"
                     /locus_tag="VCR92_000880"
     CDS             27302..27949
                     /gene="pcp"
                     /locus_tag="VCR92_000880"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEP4267963.1"
                     /translation="MKILVTGFDPFGGEAINPALEAIKKLPATIHGAEIKCIEVPTVF
                     QKSADVLQQHIESFQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RADGKAAYFSTLPIKAMVAAIHQAGLPASVSNTAGTFVCNHLMYQALYLVDKYCPNAK
                     AGFMHIPFMMEQVVDKPNTAAMNLDDITRGIEAAIFAIVDFKDRSDLKRVGGATH"
     gene            complement(28066..28785)
                     /locus_tag="VCR92_000881"
     CDS             complement(28066..28785)
                     /locus_tag="VCR92_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminyl-peptide cyclotransferase"
                     /protein_id="HEP4267964.1"
                     /translation="MSIMITKGQVRLLRTYSYDSNLYTQGLEQLNNNHILLSAGRYGF
                     SKVGVYDLTQEIFSEKIAFPDTVFAEGLTVVEDYFWLLTYKEGVAYKFDKATCNCLGA
                     YPFEGDGWGLAYDKENQCLWMTSGNAFLQKRDPKDFALLDTVLVAIESVPISMLNELE
                     YVDGYLYANIWQTNTIVKLQPDSGKVVATYDISPLLKALNLDKSHYPDLNVLNGIAHL
                     DQQRFLITGKLYPLMLEVVLD"
     gene            complement(28791..29258)
                     /gene="smpB"
                     /locus_tag="VCR92_000882"
     CDS             complement(28791..29258)
                     /gene="smpB"
                     /locus_tag="VCR92_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEP4267965.1"
                     /translation="MAKGEGHILAQNKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREITHLANELKGSG
                     MTLVPLKVYLKDGFAKVLIGLAKGKHEYDKRETIKRRDQERDIKKQMKHYNAR"
     gene            complement(29261..31594)
                     /gene="rnr"
                     /locus_tag="VCR92_000883"
     CDS             complement(29261..31594)
                     /gene="rnr"
                     /locus_tag="VCR92_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEP4267966.1"
                     /translation="MMKERIMTYLKEHGKSNVNDLAAALEMAGAKHFPSLIKTISKME
                     SQSLLRFSDDGSLALRKEREKKKEPTVQGVFRANKAGFGFLHVDENEDDMFIGRNDVG
                     YAIDGDTVEVVVKKPADRLKGTAAEAKVVAIVDRSLKTAVGTFILDDDKPKYAGYIRS
                     KNQKIQQKIYIKKEPVVLKGTEIIKVDIDKYPTRGHDYFVASVRDIVGHQGDVGIDVL
                     EVLESMDIVSEFPAEVLAEANAISEAPTAKDLIGRVDLRQETTITIDGADAKDLDDAI
                     HIKLLDNGNYELGVHIADVSYYVTEGSALDKEAIARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPNVDRLTQSALMEINSQGHVVNYQICQSVIKTTYRMTYSTVNDMIAGDEEALQE
                     FASIADDVTLMVALHRILEAMRSKRGALNFDTQEAKVIVNDKGMPVDVVLRQRGIAER
                     MIESFMLAANECVAEHFAKAKLPFIYRIHEEPKAEKLQQFIDYASTFGIHIQGTANKI
                     SQEALQAFMAKVEGQPGAEVLNMMLLRSMQQARYSEHNHGHYGLAAEYYTHFTSPIRR
                     YPDLLVHRMVREYSQPSQEKRDHFTQIIPELATSSSQLERRAIDAERVVEAMKKAEYM
                     AEYVGEEFDGIVASVVKFGFFVELPNTIEGLVHITSLPEYYHFNERTLSLQGEKSGKV
                     FKVGQPIRVKLVKADKETGDIDFEYLPSDFDVVEKIKMSDKASRRDRRKSSKSSKGTK
                     KKEPKEVAKAKTKGKTKKGSKKPFYKEQAKKKSRKRS"
     gene            complement(31688..31924)
                     /gene="secG"
                     /locus_tag="VCR92_000884"
     CDS             complement(31688..31924)
                     /gene="secG"
                     /locus_tag="VCR92_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEP4267967.1"
                     /translation="MYNLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLAIALVLAILSSK"
     gene            complement(31970..32116)
                     /gene="rpmG"
                     /locus_tag="VCR92_000885"
     CDS             complement(31970..32116)
                     /gene="rpmG"
                     /locus_tag="VCR92_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEP4267968.1"
                     /translation="MRVKINLECSECGSNNYLTSKNKSSHPEKIKVPKYCPKERKVTL
                     HVET"
     gene            complement(32113..33306)
                     /locus_tag="VCR92_000886"
     CDS             complement(32113..33306)
                     /locus_tag="VCR92_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEP4267969.1"
                     /translation="MNWRQNLKVAWLGNFFTGASFSLVMPFMALYVENLGTPKELVEY
                     YAGLAVAVTALASALFAPVWGKLADRYGRKPMMLRASFVMTFTMGGLAIIPNVFWLLI
                     LRLLTGVFAGYVPNATALIASQAPKEESGYALGTLATGVTAGALIGPLLGGILAELLG
                     IRQVFLLVGVILFLCSLMTAVYVKEEFKPIRRFEMIPTKVILKQVKSPQIMLGLFVTS
                     MIIQISAQSVAPILSLYIRHLGQTHNLMFTSGLVVSAMGFSSLFSSSYLGKLGDRFGN
                     HRLLLAALCYSFIMYFSSALAQTSFQLGVLRFAYGFGVGALMPSINSLLTKLTPKEGI
                     SRVFAYNQMFSNLGQVIGPFIGSNVAVVLGYRSVFYVTSLIVFVNLIWSLIIFRKYIK
                     VKDIV"
     gene            complement(33428..34930)
                     /locus_tag="VCR92_000887"
     CDS             complement(33428..34930)
                     /locus_tag="VCR92_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HEP4267970.1"
                     /translation="MTTMTIAKGSQPIALQLGMLNRHGLIAGATGTGKTVTLKVLAEQ
                     LSLAGVPVFLADIKGDLSNLTKAGEVTDKLAARLATIGVSDYQPQAFPVRMWDVFGQN
                     GQPLRTTISEMGPMMLSRLLNLNDTQTGVLNIVFKIADEKGWLLIDLKDLQAILKEVG
                     DHASDYSSHYGNIAKQSIGTIQRSLLTLEQEGAHQFFGEPALDVADLMQLDVASGYGA
                     INILSATKLFQSPTLYTTFLLWLLSELYELLPEVGDLDKPKMVFFFDEAHLLFKDAPK
                     VFLEKVEQIVRLIRSKGVGIFFVTQNPLDLPETVLAQLGNRIQHALRAYTPKEQKAVR
                     VAADTFRQNPDLDVARVITELEVGEALISVLNDKGQPSIVERAYIMPPKSSFAVLSEI
                     ESQQLVQSSPFASKYSQSIDRESAYEKLAAKVLEDNRLAQEAIATAKREKEAKEAIKA
                     QAATKKASRRSVGRPRKTVVEKATDAFISTTVRTIGRELVRGLLGSLRKR"
     gene            complement(35120..35713)
                     /locus_tag="VCR92_000888"
     CDS             complement(35120..35713)
                     /locus_tag="VCR92_000888"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEP4267971.1"
                     /translation="MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRL
                     YEALREAFGNQILKADGELDRTKLSEMLFSNPDNMATSSAIQNQIIKEELAAKRDHLA
                     QSQAIFFMDIPILMELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQL
                     PIEEKKPYASLVIDNSGDIAALIKQVQSALLSLANPR"
     gene            complement(35710..36537)
                     /gene="mutM"
                     /locus_tag="VCR92_000889"
     CDS             complement(35710..36537)
                     /gene="mutM"
                     /locus_tag="VCR92_000889"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEP4267972.1"
                     /translation="MPELPEVETVRRGLETLVLGQEIVAVTLKVPKMVKTDLETFALT
                     LPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVPDNKHFHVFFELKNGS
                     TLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEAALLSSQKPIKPH
                     LLDQTLVAGLGNIYVDEVLWAAKVHPGTASSRLNKAEIKRLHDETIRILALGIEKGGS
                     TVRTYRNALGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICPKCQKKRP"
     gene            complement(36709..37575)
                     /gene="rgg2"
                     /locus_tag="VCR92_000890"
     CDS             complement(36709..37575)
                     /gene="rgg2"
                     /locus_tag="VCR92_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg2"
                     /protein_id="HEP4267973.1"
                     /translation="MEKELGKTLRRLRKGKQVSISFLADEYLSKSQISRFERGESEIT
                     CSRLLNLLDKLNITIDEFVSAHSKTHTHFFTLLSQARKCYAEKNVVKLTKLLKDYAHK
                     DYERTMIKAILFSIDSSIAPSQEELTRLTDYLFKVEQWGYYEIILLGNCSRFMNYNTL
                     FLLTKEMVASFAYSEQNKTNKMLVTQLSINCLIISIDHSCFEHSRYLINKIDLLLRDE
                     LNFYEKTVFLYVHGYYKLKQEEMSGEEDMRQALQIFKYLGEDSLYYSYKEHYRQIVLG
                     GKGDEDWSEADL"
     gene            37664..37732
                     /gene="shp2"
                     /locus_tag="VCR92_000891"
     CDS             37664..37732
                     /gene="shp2"
                     /locus_tag="VCR92_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP2"
                     /protein_id="HEP4267974.1"
                     /translation="MKKVNKALLFTLIMDILIIVGG"
     gene            38646..38915
                     /gene="stcA"
                     /locus_tag="VCR92_000892"
     CDS             38646..38915
                     /gene="stcA"
                     /locus_tag="VCR92_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system protein StcA"
                     /protein_id="HEP4267975.1"
                     /translation="MTKKQFYLILAISILCFILAVSPKPPIPKHTIERKRTAMTIGHS
                     KQTPHKKEALKHKKNKNKALFLPSGDSAIKSVISMTVRLLLDDQY"
     gene            complement(39263..39661)
                     /locus_tag="VCR92_000893"
     CDS             complement(39263..39661)
                     /locus_tag="VCR92_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEP4267976.1"
                     /translation="MHRLPNRLIPEEDNNKLSRVAKEVVTEPRLNNPFLLPKKVLSLE
                     DDAAILNHLEEDRNVNKLFLEPVAAEAKREINFHPSDQQVTAKVKESSDFHQKQHQTG
                     ITYGDDTLADLTHHLLHSDGVIPSLNDKSA"
     gene            complement(39758..40828)
                     /locus_tag="VCR92_000894"
     CDS             complement(39758..40828)
                     /locus_tag="VCR92_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267977.1"
                     /translation="MMMLRDVKVKMSSLLVGCAATLLVSLSSTVAADSVHSSDRRFGV
                     GYKEETTSQFSSDQPSQVVLYRGEANTVRFTYTNQMYLMKDIRIALDGSGKSLTAQTV
                     PGMGHVYEGFQTSARGIFTMSGVPESTVPVANPNVQTKYTRYFKVIDDMHNTMYKGTV
                     FLVQPQAWKYTMKSVDQLPVDDLNHIGVAGIERMTTLIKNAGALLTTGSSGAFPDNIK
                     VSINPRGGQATIIYGDGSTDIIPSAVLWEKGSVKEPTEADQSVGTPTPGIPGKFKRDQ
                     SLNEHEAMVNVEPLSHVVKDNIKVIDEKSTGRFEPFRPNEDEKEKPASDVKVRPAEVG
                     SWLEPATALPSVEMSAEDRLKS"
BASE COUNT        12343 a         8732 c         7185 g        12761 t
ORIGIN      
        1 tttccagatt tataaatatt gttaatagat ccagttatct ctgctactct gtctaaattg
       61 tcaatatacc tcattacctc tcttttataa ggtaaagtta tatttaatcc aatacatttt
      121 ggatcattta tcagatgttt gattttatct tctaaacaca ctgagtctac caaaattttt
      181 ttatgtttat attcatccag aactcctatg ttgtgattta gatattcaaa taattcatct
      241 gatatagaat gttcaactgg attaccaagc aatgcagaat acataaattt catcctccta
      301 cgtttaatta gtttactact aacataaagt acaagcatta cacagagcta accattacct
      361 ataagtcttt agagtatcta aagacttagg tgtacaccta agtaacttac ccaccaacaa
      421 taatgataat atccattgct aaaattaaaa tcggcaaaaa ttttgaaatt ttcttcataa
      481 gcggacttcc tttcagtttt tatttattgt acaataaaaa aaaacggaat tgatttttgt
      541 tgggaaagtg ggaaaatatg aaatcaaaac ttggtgccac acttagaaaa gttcgaaaag
      601 gaaagcaaat tagtctgtgc ttcgtggcag atgaacacct ttcaaaatca caaatctctc
      661 gttttgagcg cggggagtca gagatatcgt gtatccgact gatcaatatt ctagacaaat
      721 tacacattac tttggatgag tttcttattt tacatgatga agactatacc aattccgaaa
      781 catttgctaa cctggtacag tatattcgta agcaatattc atcacaaaat atcaataata
      841 tagcatgttt actttccgac acttctgatt acactctgaa ttcttttgag aaaacaatgg
      901 taaagtccat tttacacaca atggattcaa gcatcattcc atcagatgat gaattacttc
      961 aactaacaga ttatctcttt aaagttgaaa aatggggcta ctatgaaatc cttttgttgg
     1021 gtaactgtgt acgaacaatt aactacaact cctacttcct attgacaaag gagatgttaa
     1081 ataattacat ttactcttca cggaacaaaa ctaataaacg aattgtcact cagcttgcta
     1141 taaattgttt cattcttagt atcaataagg aggaattttc taattgctcc tatttaattg
     1201 atgagataaa atcattatta gataatgaat taaacttcta tgaacagaca gtttttctct
     1261 atgcaacagg ttactttgaa tttaagcgcc aattagaaac tggagttgaa aagatgaaac
     1321 aagccataca agttcttgat attttaaatg aagacaagtt aaaattacat tacgctgacc
     1381 attttgataa actagtcaac aaagattaag tgaaatcatt ctttaccttt taacgaaatg
     1441 ccaatcaaga gtgtctcaat aaaaaatcat ctactctgac aacttttctc ttttacctat
     1501 cgacagctaa aaagccttgg aaactgctat ttccaaggct ttctttgtac tctattgtat
     1561 caattagctt attccgattt ctgttgctat tagtttaatc atgaaatctc ctaacttatg
     1621 accgaacatc caaaaaaaca gaaggaactc ccttctgttt tttaattggt catctcttga
     1681 gcttctttta attttacaga tacaatttta gagacccccg attcctgcat ggtaattcca
     1741 taaatactat ctgctgcagc cattgttcct ttacgatggg tcacgacaat aaattgacta
     1801 tctttgtcaa agcgattgag gaaatcccca aagcgcttaa catttgcttc atcaagagcc
     1861 gcttctacct catctaaaat cacaaacgga atcgttttaa cacgtataat agcaaacaat
     1921 aaagccagtg ctgacaaagc tttctctccg cctgacatca agttaagaga ttggattttc
     1981 ttaccaggag gctgcacaga aatctctata ccagcagaca agagatctgt ttccgttaaa
     2041 accaaatcag cagaaccccc accaaacatc tgagtaaagg tttccttaaa actttttcga
     2101 attgcctcaa aagtcacttt gaaacgagcc ttcacttcgc tatccatact attaatagtc
     2161 tctagcaaaa gatttttagc ttttgtcaga tctgtctttt gacttgttaa aaaagtcaaa
     2221 cgctcatgca cttcctcata ctgattaata gcatcactat taattggtcc tagtgcacga
     2281 atagtctttt gtaaatggtg taatttttct ttggcacttt ctaagtgatc aatactattt
     2341 gttacctcct ttgcgtctgc tagtgtcatt tgaaaatctt ctgataaact tttagcatag
     2401 gctcgtaagc gattagccac ttgctctaaa tgtgtctcta acttggtttg acgacgaata
     2461 aatgtgtcat ttttttcgct ttctttggtt attttttctg ctgtttcttc taagcgggcc
     2521 tcatagtcct ctatttcaaa tcttaattgg actaaacgtt tttgagcacc agacttatgc
     2581 tctgtggcat cttgtaactg tttttgccac tggggtagtc tttgaatgct gtcttgactt
     2641 acgttgttgt ttagtatgct ttcaagtttg agaatatttt gctggcattg cttcagctga
     2701 gttcttagac gagattgatt agcttgctca aatttctttt cattaagtaa atctctttct
     2761 tgcaaacgag cttgagataa agcttggtga atgttttgtg ttttttgcct aaccaaatct
     2821 ttgttttctt tgatatcatc aatatcacaa gttaaggcac tttttttctt agcaatagct
     2881 gttaatgctt cttcaatacg agcttgctct gccaataaag attcatcaga atgagtcgtc
     2941 tgactttgat caagggcagc taacaaagcc tttgaatctt cttgtttttc ttgcaattgc
     3001 tgataagcca tttgagctct ttgttcagct aagcgtgcct ggtcaccggc taatttcaat
     3061 tgtgtcagtt cttctttttt tgctatcaaa tcgctttgca aggcagctac ttctttttca
     3121 gttattttta attgctcaac taatcgcgtt aattcctcac tgatttgttc taactctggt
     3181 ttgataaaag ttgtattgct ttgtctatta gttcctcctg aaaaagaacc acctggtcgt
     3241 aattctgttc catcaagagt aacaattctt accttatatc ctaataagcg cgctgcaata
     3301 ttagcttgat caatagtttc aaagatagca gtactagata aaaggttttg gataatagct
     3361 gaaagactat catcatagcg aaccaatgat tctgcagttc ccagataacc ttcacaagtc
     3421 gctaattgac gatgatagtg ttctgataat gatctagcct ttatagtagt taaaggtaaa
     3481 aaagttgctc gtccttggcg attttttttc aaataagcaa ttgctctttt tgctgcagct
     3541 tcgtctgtta caataatatg ctgactatta gcacctaatg caatttcaag agctgtttgg
     3601 taatcagaat caaaagaaag gtgttcactg actgcaccta tgatccctcc aagctttttt
     3661 tgtgattgaa ggacagctcg tactcccgca tagaattgac tatgactttt ttgaatagat
     3721 tctaagctag ccttacgagc ttcttttcct tttttttgat tcaacaagtc aaatagtctt
     3781 tcttgcttca gttggtaatc tctttctaat tcctgaacgc gtttatcacc ttcttgataa
     3841 ttttggagca acatttcgac ttgctctttt tgagctttat aatgagcttg agctttttga
     3901 gactcgtcat taagttgatc aagcttagta acaagcagct gatattcttg agccttatgt
     3961 tgacgagcct gtttttcttt gtctaaatgg gcttttaaag ctgtcagctg atttgataag
     4021 gccgcctctt tttgcatcaa taatacaaac tcttctctta gagtttccat taattggtcg
     4081 ggatcacttg aaaaacgctc taatgcattg ctcaattcgt ttaactgttg tttgacatca
     4141 caaagttgtt gatcaatatg caataattgt tctgtacgct gcttttcttc tgcttgaaaa
     4201 ccatccaatt gttcttgtaa ctgttcgagg tgttttttgg cttctgcctt tttctctgct
     4261 tcttggccac tttctagctt aaccaattca atttgctttt ccaagtcagc tattagcttg
     4321 gttaattcta ataatgttgt ttgggtttga tctgactctt gactaagaac ctgctttttt
     4381 tgcttgaatt tttggtaatc ttcttccata gattgacgct tagcgtaata agatgctaag
     4441 tcttgttgta aagcagctaa agcttcagta tctttagtct gtctttcttg agctatatca
     4501 atatctttga ctagaatatc tagttgtagt tgcttacgat tggcatcaag ttctaaaaat
     4561 tgtttagcta ctttagcttg cttttcaagt ggggccaact gcgtgtctag ctcataaata
     4621 atatcctcta gacggtctaa attatcttga gtttgattta atttaatctg agtttctttt
     4681 ttacgtgttt tatattttaa aacaccagct gcttcttcaa aaatggcgcg cctttcttca
     4741 ggtttactat tgaaaatttc ctctacgcga ccttgagaaa taatggagaa agaatcacga
     4801 ccaagccctg tatccataaa caaatcatga atatcacgga gccttacctt gcgaccatca
     4861 atcagatagt cactatctcc atttcggtaa atatgccttt cgacacggat ttctttcttg
     4921 gcagttttta taaaatgatc ggaattatca agaacaaccg ctaccttagc atagtttaga
     4981 ggattacggt tttgtgtccc agcaaaaatg acatctggca tcttgccccc acgcagattt
     5041 ttagcacttg attctcctaa agcccaacgt aaactttctg taatattact tttacctgaa
     5101 ccatttggtc ctacgactgc agttactccc ttataaaatt caattttagt cttgtccgca
     5161 aaggacttga acccttccaa ctcaatttct tttaaaaaca tctaaacctc actaagttgg
     5221 gcaagggcat ttttagcagc atcttgctcc gctaattttt tagacttacc taaaccttta
     5281 ctaaggacag caccattaac aactatcgat acctcaaatt gtttagcgtg ggcaggtcct
     5341 ttctcactaa tgacttgata atcaatagcc acatcacctt ttgtttgcaa aaactcttga
     5401 agacaagttt tatagtctct aaccctttca aaattccctt tttccacctg agggatcatg
     5461 acttgtttca agaagcgacg tactgcatca atccccttat ctaataaaag agcacctaaa
     5521 aaggcttcaa ataagtctcc taaaatagta tcacgacggc gaccacctga cttttcctca
     5581 ccttttccta gtttgatata agcgtcaaaa gaacaaaatc gtgaaaaacc tgccaagctt
     5641 tcctcacgta caatcatgga acgtaactta gacatatctc cttctgtctt tttaggatac
     5701 tttgcaaata aatactctga aataatcaat tgtagaacag cgtctcctaa aaattccaag
     5761 cgttcattat gtgaaacgtt taggagacga tgctcgttag cgtaagaggt gtgggtaaaa
     5821 gctgtttcta gtaaagtcaa atcattaaat tgaatatcaa aagatgttga gagtaactct
     5881 tcaagctgtt tcataaaaaa tccctttcat atttgtcagt agaccttatt tagtatacca
     5941 aaaatccacc tagaaaaccg actctaagtg gatttttcgt gatttattaa acatcttaaa
     6001 tacccgtcaa aggaaacttt ctcatacaat caaaagactc tacactatct gaggggaatt
     6061 tcccactaca gatagtatag agctattttg tttttagtct gaacaactaa aaaactacct
     6121 tatctttata atcctcaaca cctttgataa atagatcaga caagccaaaa ctacaggcta
     6181 atttaagtct attgatgctc taaaggatga ccaatgagag ttcattgaac tcagaagaca
     6241 atacgcttta agacatcaaa aaaatagccc tgactggtat atcaccaatc agcgctactt
     6301 tgcatattct cttttagttt cttatctcaa atatcagtta atggacaagc agtatctgga
     6361 gaggtatcat ggaccgtaaa gtctgtacct actgctaaat ctgccatagc cagttgattg
     6421 accatcgtca tatgcgctaa ctctttgatg ttattttctt tactcagatg acctaggtat
     6481 atttttttgg tattgtaccc caggcttcta atcatggctc ccgctccatc ttcatttgat
     6541 aaatgtccta aatcagataa aatacgctgc ttcaagctcc aaggataaga gcctgatctc
     6601 aaaatttcaa tatcatgatt ggattcaatc aagtagccat ctgcattttc aataatacct
     6661 gtcatcctat cactgacata tcctgtatct gtcaacatca caaaagactt attatctttc
     6721 ataatccgat aaaattgagg atcaatagcg tcatggctga ctccaaaact ttcgatatca
     6781 acatctccaa aggtcaaaac tttatccctt tggaaaatat gtttttgtga ggcatcaagc
     6841 ttacctagca tattgcactc atccatcagc tgccatgttt tttcattagc atagatatcc
     6901 aaatggtatt tgcgggccat aacgcctaca cccttaatat ggtcagagtg ctcatgggta
     6961 atcaaaatag catccaaatc ctcaggtttg cggtcaattt cagcaagaag actggtaatt
     7021 ttcttaccag taagccctgc atcaatcaat aagcgttttt taggtgtttc taaataaaaa
     7081 caatttcctg tggacccaga tgctaaaata ctatatttaa aaccactctc attcattgat
     7141 tagtctacat cttcctccca ttcttcatag atggctgcat ctttttcata aggcaagaca
     7201 atagtaaagg tcgatccttt accatagtca ctcttagccc agataaagcc atggtgctgc
     7261 ttgatgattt ctttagcaat ggcaaggcct agaccggtcc ctccttgggc acgacttctt
     7321 gccttgtcta cacgatagaa ccgatcaaaa ataagaggca aatctgtttt agggatacct
     7381 agtccttggt ctgaaatgga aataattaat tgggtatctg ttgttttcat acggactgtg
     7441 atttttccac catctggaga atacttaatg gcattgttca aaatattctc gataacctgt
     7501 gtcattttat cattatcaat ttcaatccag acagaggtaa tagggtaatc tcttacaatt
     7561 tcatagactt ttcctgtacc tgtatgctga tttttaacca aatcaaatct gtttaaaata
     7621 gaagttataa aagcagtaaa attagtcatc tctactgcta attgggttac ttgattatca
     7681 atccgagaca ggtttaaaag atctgaaatc atacgcatca tccgattagt ttcatcaaga
     7741 gaaactttta tgaaacttgg agcaatatct tctttaagtg caccttcatc aagagcctcc
     7801 aagtaggatt taaccgaagt taaaggggtc cttaattcat gacttacatt agagacaaaa
     7861 agacggcgtt cacgttcttc tttttcttgt tctgtggtgt catggagcac cacaaccaag
     7921 cccgaaataa aaccactctc tctcctattc aacgcaaagc gcaagcgtaa tgagacaaac
     7981 tcacccatat catttcggct attaacagtt accactggtg ttttagatac caaatcacgg
     8041 taggtatatg aagtatcacc ttctaacaaa tctgtaatgt ttttctttag tgcctcttct
     8101 ttacttaaat ttaattgctt gcgagctgtc tcgttaatca tgatgatttt accagaccgg
     8161 tctgtagcaa gtacaccatc tgacatataa gccaaaatac ttgccaagcg atttttttct
     8221 tgggcaagat tttcatgcgt caagcgaaaa acatctgata ggtcatttaa ctggtctgaa
     8281 agctccatta actcaatgtc tgctttttcg tcgattatat cagtatagcg accattaatc
     8341 aagtctcgga ttttatggct catcatccga ataatacgtg catttcggta atcacgcacc
     8401 gcaagatgga taaagtaaaa agcaacaaaa acaagtaaga taaggatcgc taattcaaat
     8461 gtggataagt ttccaatgat atctctagtc ataagatttc atgtagtacc caacaccacg
     8521 tcttgttaaa atatactcag gacgacttgg tgtgtcttca attttttcac ggagacgacg
     8581 aacagtcaca tcaaccgtgc gcacatcgcc aaaataatca tatccccaaa caatttccaa
     8641 taagtgttct cgtgtcatca cctgacccat atggttagct agatgatgca atagttcaaa
     8701 ttcacgatgg gtcaactcta cctcttgacc atgtttttta gcaacaaacg catctggtaa
     8761 aatctgtaaa ttaccaatgg ttagttcctg tgtacctgaa gaagcatttt cttctgcaac
     8821 agccgtttca atagtttcgg tacgacgcag atgagccttg acacgtgcca gcaattcccg
     8881 attagaaaag ggcttggtca cgtaatcatc agccccaatt tcaagtccaa taaccttgtc
     8941 aaactcacta tctttagccg acaacataat aatcgggaca tgactggttt tacgaatttc
     9001 cttggctact tcaagaccgt ccaactcagg gagcatcaaa tcaagaataa ttaaatctgg
     9061 cttttcttct tcaaaaattg ttaccgcttc gcgtccatca aaagctgtaa caatgtcata
     9121 accttctttt gtcaaattaa acttaataat gtcagaaatc ggtttttcat catccacaat
     9181 aagtattttt ttcatgtcta tacctcagaa agttcttgta attgatatta caatttgtga
     9241 tttttgtggt taataaaaaa tcacaaaact atatttttct aaattatttc tacctgatta
     9301 taccaaaaat tcagcctaat tgacaatgac gactaccgtt acaaatagag tactttctaa
     9361 aaccaaccct ttataggatg aatttgacgt ttgaattgct tagcagattt tttgactctg
     9421 gcaaaactac tcttgttgtg gtaagcaaaa agtcctttgg cattaaaata agagaacata
     9481 aagtcatctt tttgagctct aaaccactga cgaaatactc tttttggcga tcgaaatcct
     9541 ttaagggtgt cccttctaaa ctgaggatcg tgacggctaa tcggatcaac atctaaatcc
     9601 caatgtctag gaccatctgt gccatagtta aaagatgcac cattgacaat tcctttttcg
     9661 gtcactactt ctgcatcaac ttcattaaga aaaaagcctg tgctatctag aataaattcg
     9721 gtatgaaacc aaagaagtac ttttatatta taggaaactt cttgacttgg aaaaatgact
     9781 ttattatctt caaatcttag tttattatgt aacctggcag aatccatcaa ggtataatct
     9841 ggtgcttgcc gccacaaaca aggccctttt ttagacctca aaaaaagggc cagagcttgg
     9901 gcgtctgtca tctcaatcat tttataatgg tttctgatag attgagcttg ttgactagag
     9961 atgacataac gaaattgatg caaacgcttt tcaagctcac ctgcttggct tagtgttttg
    10021 ccaggaaaag cttgatcaac taagctagcc aactctttcc aaaacatatg atctggcaat
    10081 agagatggat ggaatcgggt gagtagcgtt tgagtttcat gcaactgacc acttagctca
    10141 aatggcatct ctaccaaatc aagaagaaac gttagtaact gcttagctga ttggttttct
    10201 ttttcaatag gccatattac ccagaaagtt ggagaaccaa gtcgattatc aatgataggc
    10261 tctttagcta tagcacgaaa tgcttggttt gataaacctg cgttttgata gcatttcaag
    10321 gcctgatagc gatctaagat agcttgtttc atggccttct cctcatcttt tttgaccata
    10381 ttataacaca tctaaagctg aatcgtcact tgtatctcac tataagcaaa acgaaacctg
    10441 aagtggttaa ctaagccact gtttgggtat tttatttaaa agaacttctc gattaatttt
    10501 accattatct tttaaaggca aacaatcaat cacaagatag tacttgggaa gttgtccaga
    10561 gtttaaataa agagctaaaa agtctttaat aggtgctagg caatccttct tagtcaaaac
    10621 taatactaat attagggttt cgttttctcc ttttcctatc tttaaagcgt gcgcttcttt
    10681 gacgtttggc gcttggtgag cgagttcaac taggctaggc aggtggcatt tcactcctcg
    10741 ttgattaacc cagtcatctt gtcgcccttc taaaattaaa cccgctgggc tcatttttcc
    10801 taagtctgag acactgtatg gttgtgacat tccttctaca ctataaggag tctctacaaa
    10861 aatttcctta tctttgaaac tgatagacac atcaggaaag ggctgtccta ccaaaccatt
    10921 aattttgaca gcagctctgc cattacacca cgttataaaa gataattcac tagccccgta
    10981 gaaaatgaca atttcaagct gaggaaattt tttgtaataa tgtcttagta attcttgtga
    11041 tatcatttgc gaagaggtca ataagtgagt cgcagtcatg ttgttcttag tcaaataagg
    11101 tagcaagcga tttaggtagg tcggtaaaag gtaaaggtga ctcacctttt ttgcttgcca
    11161 taagcttaac cacgttttca aagacagctt ttggcttaaa accagacatc ccccggccca
    11221 tagttgagct aatgctaagt taagattgcc agtaaaacta aaactaccat gtaagaatag
    11281 acaactatta ccagtcatac caaacacctt attttgataa tcaaaaagtc tcgtccaagt
    11341 tgatagacaa cgccaaaata attttgcttt gccagttgtt cccgaactca aaacagcaaa
    11401 atcagctttt ttaagaagct cactatcgac gtgttttatt tgctgctgaa atgtacctga
    11461 gatattaggg tgtaaaatga taggacaact gccttctttt aatcctcgta aaaaagagag
    11521 taactgatta agatagcgac tatgactgat gatatatggt acactgtctt ttattgtctg
    11581 atcctttatt aaaaccgctt gccatagctc ttgataagtc aagcttatct gatcggctac
    11641 gatagctttt ttatttgggc attgctttgc ccaatattct agctttgtca gcatgactaa
    11701 actccttatg atattttagt aaaacagcaa acccttggcc accagctgct gctatagcag
    11761 ctattccata gcgtccattt ttaatctcta aagccctcat taagtgcaat attataatgg
    11821 ctgctgaggc accataggga tgaccataag ctaatgcacc accaaatata ttatagcggt
    11881 ccaataaatc tggataatgg gtttcaaata gaccatcaat aacggcaaag gcttcgttcc
    11941 attcaatcgc tgtcatatct gccatcccta gaccatgttt ttccaaaagg acttgactag
    12001 ccttaatcac cattaaaggg ctacgctgtg ggtctcctgc tacttctacc acatcaatca
    12061 gtttaaaagc tgaaggctga ctacttagct gtaaaaaggc agcagcatca tgggttaggc
    12121 aggcattggc tgcactaatc acgtgatctt ctcctaagat agggggtacc tttgacaaca
    12181 ccttacttga caagcgcggt cgaatacctt gatcactggc tcctggcagg tctagaataa
    12241 gatcagctaa cagggcttgc tcctggcaat aactagcctt ttgatgactt ctcaatgtcc
    12301 agtgattcaa atactccttt gtaaagccat gctctcttgc cactcgttct gccccttcaa
    12361 tcatcgcaaa agggctgata ctatctggag aaaactgagc taccttgtag gctccttggc
    12421 gccaatcagc tgaagcatat accgattcag gttgtaagga gctgctttca atccctccca
    12481 ctaaaaggtt gcttgccata cctgccttga ttttagcata acccacggaa agagctgcac
    12541 cagctgatgc acactgcata tcaaccgtca aagcagagac agattctcct aaatgagaat
    12601 acagggtcat caggcgccca atattaccac ccgttccgac ggcattgcca caaatcactt
    12661 ggtcaatggg aactggatac ttattttgta aagcattgat gagctttgct ccaaggattt
    12721 ctggttgttc tttagcaaat tgtttcccta ctaaaccgat aggggttcta aggcctgcag
    12781 caatataaac atccgtcatt atattgacct cctttatttt cgatgtcctt aaatggttat
    12841 tatataatta tttctgatgg ttttcttttt tgaactaata actgctaaaa atacacctaa
    12901 attaatttag agaatctctt tagtctcgct agtgtgccat caataaaatc tataaaattc
    12961 tctaacgtca ttgaaatgtc aagtcccaca actattgtcg tagaagtcac ttactttgtt
    13021 gctttaacat tcaaactgta acctttgttt ttgatacagg gtgactttat tatactggaa
    13081 aaccattcct aagaaaagaa aatcttatat agaataaaga attagacacc ataaaaaagc
    13141 taagctgtga cacttaactt ttttatggta ttgacaaacc ttgtctttac tatttattga
    13201 tagttaatgc ctctaactaa aataaaagcc atgtctgtat cagcctgcaa ggcatctgct
    13261 aagctggtat cgttactaga tttgacaggt ctcataaagg caaaagatct caaagttcca
    13321 taaacgttat ctagcaattg catgcaacca cttgaaatat atctgcttat gttattttac
    13381 cgcccttaat ttagaccaat ctgctgatga tggttccaaa caatgcctct aggaacctgc
    13441 actttcataa gcatctaggc cccatttcca aagcttaagc gacaaggcca aaaccagtaa
    13501 cgacaccact accaagcctc caatattaaa gagcaggtgc tgacctgtta aaaaataaga
    13561 agcagggtaa taagctgtaa aagcaaaggg aatgacaaaa ctgattaacc accgcaaaaa
    13621 ggaatggtaa atggacatag ggtacttgga aaagtcatta aacatgtaaa aaatataaat
    13681 aactgcccca gactgcttgg tccaaaaaga aatgctggcg gtcgcaattt ttaaagaggt
    13741 gtaaatcaag gtcgcaaaag gaataaccaa aataaacaaa agcaccttag gaagagtcca
    13801 tacgatacta ccagccgtgg tcactaataa gataacccca accaataatt cacccagggc
    13861 atccacttga aatgtctcaa ccaaaacatg aaacaaagga ctgattggtc tggtgaggta
    13921 cttgtcaaat tctcctttgc ggacaagccg ttgccctaaa gcccaaagat tgtcaaaaaa
    13981 gaggtgatca attccctttg gaatcaaaga aaagccataa ataaaggcaa tttgttcaaa
    14041 cgtccagcct tctaaagaag ggatatgttg gaaaagtacc gataaaaaga gcagattaag
    14101 tccctgagtg agaaaaacac ctagcactcc caccacaaaa tcaaccttgt attccataat
    14161 ttgtttgagg tattgtttga taaaaatagc gtgcatacgt ctcaattttg ccatctcacc
    14221 ctccttgaat cgttaaatgg tactgaacct ttttccagat gacttgcgat aagactacca
    14281 tcaccagtaa ccaaaagatt tgcaaactta gggccaccat tatctgacta aggctgtatt
    14341 tcccaatgac aatcataact ggcgtgtaaa ccaaagagga aaacggtaga aaactaagca
    14401 ctatataaac cactttagga aaaaaagcca atggaatcaa actgcctgac ataaaggcaa
    14461 ccaaggcatt tttcaataaa ttagaccccc aaaggttttt aaagacaaat gctgaaaagc
    14521 caaaacaaat gttgaaataa aaattgatta aaaaagctaa taaaaggcta actaaataca
    14581 gacaactgct ggctaggact tgcaaggtag acagccccgc catgacttta ataccagata
    14641 agaccattaa aaaaggaaag ccgacactca ttagcacaat ccagcgaaaa ccaatttcca
    14701 taaagaggta agaggctgca aaatgaactg gtcgaagcag gcgcatgatg atagaaccat
    14761 ctttcacttc ttcgccaatc ataaaggagc tgtctgattt ggtcagtaaa gtggtcacaa
    14821 aactcatgat aatgtaaaag gtcatgtcag acagagtaaa accattgatt aaggattgct
    14881 tagacgaatc aaaaacagcc ttccagaggt aataagccac aaaagccccc atgacatctc
    14941 caatacgata caaaaagaaa ttaacgcgat aggttattaa ttcctgaatt cctgcactga
    15001 gaaagggtct ataacgtttc caaaatgacc acatcttaaa gctcctttcg gtagaaacga
    15061 cgaacaatat cctcaatatc tacatcagtc atcttcaaat ccctgaccgc aaaatcagcc
    15121 atggtttttt gaataatgtc cgctgtttga tagcgcgaac tgtcatattg aatgtctaaa
    15181 ctaagctcat gccgttccac tgtgatgtca ggtaagccca taaactgtga gaccacctgc
    15241 tcctgccctg gcttcaactc aaaagacaga ctcttcattt ttccaaagct ttgctttaat
    15301 tgggtcaccg ttccatcaaa gatttcttgc cctttatcaa tcatgataat ccgatcacag
    15361 agctgttcaa tatcactcaa atcatgggtc gtcagtaaaa tagttgtctt ttcttcttga
    15421 ttaatttgag taatggcacg ccgaatgttg tccttcacag aaacatcaag tccaatcgtt
    15481 ggttcatcta aaaacaatac tttaggatta tgcaacaagg aagcagcaat atcagctcgc
    15541 atccgctgac cgagtgataa ggtccggaca ggatccttaa taaactcatt caggtccaaa
    15601 acctcattta aaaaatccat gcgcttgcga aaggcttttt caggcacatc gtaaatttct
    15661 tttaaaacga cataggtctc ttgcaaggcc aaatcccacc atagttgtgt tcgttgacca
    15721 aaaacagctc caatgtctct cacataatct tgacgattat cttgtggaat ctttccgtta
    15781 atgcgacagt aacctgatgt aggctttaaa atacctgtta acatcttaat cgttgttgat
    15841 tttcctgcac cattggctcc aataaaacct aaaatttgcc ctttgggtac ctcaaaagat
    15901 aagtccttaa ccgcctcaaa gatttctctt tggggatgaa caaaggactt caaggctccc
    15961 tttaatcctg gctctttaat ggttttggaa aaattttttt gaaggtggga cacttctatc
    16021 atcaccattt accattcctc gtttctgtta tcgtcttatc accgttacta aacaatttat
    16081 tataacacca tgaaaaagac tgtgcaaccg tttgcttaat tttttaagaa agaaaaagaa
    16141 gcccataagg acctcttttt gccattgatt aagcttgtgc atctggacat gacttgcgag
    16201 caatgtctgc caagatgttt tccacaaatt cttccacaga ttcagtgtga gtcgccttac
    16261 taccatagcg gcgaacattg actgatttgt cttccatttc tttgtcccca acaattaatt
    16321 ggtaaggaat tttgctggtt tgagacgcac gaatcttgta ctgcattttt tcattgcggt
    16381 catcgacatc tgcacgaaca ccacggtcac gaagggtttt tgctacttcc caagcatagt
    16441 caatgtgggc ttcatttgaa attggaatca cggttacttg gtgaggtgcc aaccaagttg
    16501 ggaaagcacc cttgtaagtt tcaataagga tagcagtgaa acgttccata gttgagataa
    16561 caccacggtg aatcatgact gggcggtgtt cttcgccatc tgcaccaatg tatttaaggt
    16621 caaagcgttc tggcaacaag aagtccaact gaatggttga tagggtttct tcgttaccaa
    16681 gagctgtttt cacctgaata tcaagcttag gcccataaaa ggctgcttca ccttctgctt
    16741 caaagtaatc tacacccatc tcatcaagtg cagctttaag catactttga gcattttccc
    16801 acatctcatc attgtcataa tatttacgag tatcgttagg gtctcggtat gacaaacgaa
    16861 aacgataatc agtcaagttg aagtcagcat aaacatcaat gattaattga agggcacgtt
    16921 gaaattcttc ctggatttgc tctggtgtta cgaaaatgtg gccatcattc aaggtcattt
    16981 cacgtacccg ttgaagtcct gatagggcac ctgatttttc gtaacggtgc atcatgccaa
    17041 gctcggcaat acgaataggc aattcacgat aagaacgcac atgattttta tacacttgaa
    17101 tgtggtgtgg gcagttcatt ggacgaagaa caaactcctc accatctccc atatccatta
    17161 cagggaacat atcttcttga taatgatccc aatgacctga tgtcttgtac aattctacag
    17221 aagcaagtgg tggtgtgtaa acgtgttggt agcctgatgc taattcttta tctgtgatgt
    17281 agcgctcaag tgtacgacga atagtcgctc catctggtaa ccaaaacggc aagccttgac
    17341 caacttcttg gctaatcatg aacaagtcaa gctctttacc aagcttacgg tgatcacgtt
    17401 ctttggcttc ttctagacga gtcaagtaag ctttgaggtc ttttttatca aaccaagctg
    17461 ttccatagat acgttgcatc atgttattgt cgctgttacc acgccagtaa gcacccgcca
    17521 catttagcaa gtggaagact tggatacggc ctgttgatgg cacatgaggg ccacggcaaa
    17581 gatccacaaa ttcaccttga cggtaaaccg tcaagccagc accagcatgc tcattaatca
    17641 attctacctt gtaaggatca tctttgaaca attccaaagc ttcttcttta gtcacttctt
    17701 cacggataca tgggtaattt tctgtcacga ttttttgcat ttcagcttcg atacgtggca
    17761 aatcttcgtt tgaaatttgg ccttcagcat tatctgtatc atagtaaaag ccttctgcaa
    17821 tggcagggcc cacacccaaa tgaagatttg ggaacaagcg ttttgcagct tgggcaaata
    17881 aatgggctgc agagtggcga agcacctcat aagcatcttt gtggtcaggt gtcacgattt
    17941 caatactgcc atcttcttca atggcacgag tggtgtcaat gagttgatca ttgaacttac
    18001 cagctaaagc ttttttagcc aatgatttgc tgatggactc agcaatgtca aacgttgtta
    18061 caccagattc aaattcacgc acggcgccat ctggaaaagt aatcttaatc atttgctttc
    18121 tcctttaagt cagttaagat ttccactaaa acatggatag taagacaaat tagggacaag
    18181 aggttagtga atagctcaat accaccacgt agaagaacaa taccttattc acgaatctac
    18241 cctccctagt ccttaaaaac aaggctaatc ccctccaaaa caaaaaaact gaccgcatcc
    18301 caaaggacgc aatcagcgtg gttccacctt aatttatgca gggcaaaaaa catgccttgc
    18361 acctctagtg gcgataaggg ggccaccctt ttatgtttgc ataaaaacca ggaaggagta
    18421 tcagattagc tatccttgtg ctctttccac caaccagcac tcgcttaaaa gattctgtcc
    18481 aatctaactt gtcttcaaga taattatagc aagttttcaa aaatttacaa gtcttaatcc
    18541 agaaaatctt tgatagcatg gaccagcttg ataggagcct tgactacttt tactgaggtg
    18601 atagctgtga ccttagcagc acgtttaggc aagtgaatag caccttgcac taattttaga
    18661 gaactacttt taccagaatg attaagataa agactcagct tttgagcttc tttgctattt
    18721 ctagcaatta acgtatctaa atagaacgtg taaatagatt ttccaaagtg ctgtgctgag
    18781 atttcataac gtttttttgc taataaccgt ttatccataa ctggtgtttt tagtatggca
    18841 tcaataatag catcagttaa atctgtttca gcgtaataaa gagtgccaaa cattttatca
    18901 gtcaccacat catctaaata aggattgcca tgagcaataa taggagtgcc actagccaaa
    18961 ctttcaatat aggtcaagcc ctgagtctca ctggtcgatg ctgagataaa gaaatcacaa
    19021 gccttatagt acagagcaac cttatcatga ggcaccatgc ctgtaaaggt cacgtgtttg
    19081 tcaacctcta actgcatcgc caagtgtttc aaatcttgca aataggggcc atctcctaca
    19141 ataataagct ttatcttggc attttcagcc aaaatagctg gcatctgatt gatgatagct
    19201 tgaatatttt tttcataaga aatccgtgac aaactcaata acatggtttc atcaccagca
    19261 atgcccaatt ctgcttttaa gttggttact tcttctgctg tgatgtcatc acgaatatat
    19321 ttttccaaag gaatgcctgt tgggataacc cgcttaggga tagtaacttc gtaaccttct
    19381 agaagattga ggacaatcct acttgggcag ataaccccat ccaaatcctt caaatagccc
    19441 ctaagaagag gtttgaccat acttggtcga atgatttttc cgttggcaat ataactcacg
    19501 tagtcctcat attgggtatg gtaagtatgg acaacaggaa ttcgcaaagc tttgcctatc
    19561 attttcccta acaagcctaa gctaaactca gtttgcgtat gaataatatc aagattatag
    19621 tgttttgcaa ttttgtatga cgaaatgagg ccacgataaa ccacacgtct atccgtaaat
    19681 gacacaaaag gaacacttgg cagtcgaata atggtcgggt cttcaaagcg tttgacatct
    19741 ctatcagtag tggtgaaaat ataaacttcg tgaccttctt tttctagctc ttcttttaac
    19801 gtacgaatac tagtagcgac tcctgaaact tgtggaaaat aggtatctgt gaatagacct
    19861 acacgcatct tataactcca ttactttttt atagacatct actaaggcat ggccaaccgt
    19921 ttctaggcga cgactctggg caaccttgta accagcttca actttgttgc tggcaccaga
    19981 aaagactttt ttcagagctt ctataaaacc tggtatatcg gttgctaatt ccgcactact
    20041 ttgatcaacc catccgtagt aaactggtat atcacgtaaa acaaggtgct gacgactggc
    20101 caaggcttct aagacaacaa tgccttctgt ttcttcacga cttggaaaga aaaaggcatc
    20161 tgcaccagtc atggcacctt cataaacatc ccctttaatg tatcctggga aaataagatt
    20221 tttcgggtgg ttaccattga ccatttggcg aacttgagca ggaatgaccc atttgttggt
    20281 ctcgccaaac cagataaaac gaacatctgg catagcttgg gcaactttga caaagtcatc
    20341 aattcctttc ctcagaaaaa ataatcctgc tcccataacc actttttcac cctctttaat
    20401 gtcaaagtag cgacgaaaag ctgcttcctt tttagaatct gctccgtact gctccaaatc
    20461 aatcccattt gacactgcaa aaataggtga cttcactcca taactctcaa tcaaagactt
    20521 agaatatagg gtaggggtaa tgatagcatc tgccttattg taaaagtgac aaaggtattt
    20581 tttaaaccaa ggagataata gatttgaaaa aataaaagaa tttctaaaat cttcttctgt
    20641 agaatgccca tgcatgataa ccttcttacc agctttttgt gcttttatca tcagcagcca
    20701 actttttaaa ccataggtat tgagatgaac caaatcataa gtttctcttg gattagtcgt
    20761 aaaatgttga ccaacaagtg acaaggcttt agcctgatgc ttaatcgctc gaccaattcc
    20821 tgattttctt agataatttt ctgcttctaa atacaataag actttcataa gttctattat
    20881 agctcatttt atagtatttt tcactaagac atgcaaaaat cagccctaag gctgatttta
    20941 gtattgaaga aacagtctat tgtgatactt tttgttagat ggtgctcata agtcacagtt
    21001 acttagttgt cccacgtttt ttaataccat gattcaaaag aatttctttt tcttccaact
    21061 cttctttgtt catgatttta gtcaacatcc gcatgctaac agcacctaag tcataaacag
    21121 gttgactgat agaactcaaa ttgggacgag tgtattgaac cactggtgaa tcgttgctgg
    21181 tgatgatttc aaagtcctct ggtacgcgtt tacctgcttc aaacaagccg tttaaaaggc
    21241 ctgctgccaa ttcatcttca gccacataag ccgctgttgc tcctgagtta atgacgcgct
    21301 gcgccaattc aaatccttct ttataagaat agttcgcttc aaaaacaaga ccttctttga
    21361 agtcaagctt attgtgcttc aacccttctt tgtaacctgc taagcgcact ttaccattga
    21421 tatcatcaat gagtggtcct gacacaaaag cgatacactt atgattttca gctaaaatat
    21481 caacaacgtt tgacaccgca gctctatagt caatgttgac gcttggtaat tgatgatcaa
    21541 gatctacagt tcctgccaaa acaactggag tacgagagcg tgaaaactcg gcccggattt
    21601 tttctgtcaa gtgatgcccc ataaaaataa taccatccac ttgcttggca aaaagggtat
    21661 tgacaacatt aacctcctta tcatcatctt catcactgga ggcaagcaca atattatatt
    21721 tgtacatagc ggcgatatcg tcaataccct tagctaagat agaaaaataa ctatttgcaa
    21781 tatttggaat cacaacgcca acggttgttg tctttttgct ggcgagacca cgcgcgacag
    21841 cattgggacg atagtcaagg cgatcaataa cttctaaaac tttcttacgt gtattttcct
    21901 taacattttt attgccatta acaacacgac taacggttgc cattgaaaca ccagcttcac
    21961 gggcaacatc ataaattgta atggtatcat ctgtattcat tttttatctt cctttctatt
    22021 tgaaaatgac gctttcaaaa agtattttag catgatttgt aaccactttc aagtgttata
    22081 ggttaatttt tgaaaaagtt ttcaaaaatt aactcgaagc ttgatttttt aagctttttt
    22141 tgaaaaaata gtaagtagaa agaaggttag cctatgacaa aattagacca aatacgtttg
    22201 tatcttgacc aaaagggagc tgaattggcg attttctcag atcctgttac gattaactat
    22261 ttaactggat tcttctgtga cccacatgaa agacaactgt tcttgtttgt ctaccatgat
    22321 ttagctcctg tgctttttgt acctgccctt gaggtggcca gagctagcca ggccatatca
    22381 tttcctgtgt ttggttatgt tgattctgaa aatccttggg aaaagatcaa ggccgtttta
    22441 ccaaatacag cagccaaaac catttatgtt gaatttgacc accttaacgt caataagttc
    22501 catggcttgc agactatttt ttcaggacaa tttaacaatc taacccctta tgtccaaggc
    22561 atgcgcctcg tcaaatcagc tgatgaaatc aataaaatga tgattgccgg gcagttcgct
    22621 gataaggctg ttcaagttgg ttttgacaat atttccttag atgctaccga aacagacgtc
    22681 atcgctcaaa ttgagtttga aatgaaaaaa caaggcattc ataaaatgag ttttgacact
    22741 atggtcttaa ctggaaataa tgcagccaat ccccatggca ttcctggaac aaataacatt
    22801 gaaaacaatg cccttcttct ttttgactta ggtgtcgaga ccttaggcta caccagtgat
    22861 atgaccagaa ctgtggctgt tggtcagcca gaccaattta aaatcgatat ctacaatctc
    22921 tgcctagagg cacaactagc ggctattgac tttatcaaac caggtgtaac agctgctcaa
    22981 gtagatgctg ctgctcgtca agtgattgaa aaggctggat atggtgagta cttcaaccac
    23041 cgcttgggac atggtattgg catggatgtc cacgaatttc cctccatcat ggctggcaat
    23101 gacttggtcc ttgaagaagg catgtgcttc tctgttgaac ctggtattta cattccagga
    23161 aaggtcggtg tgcgcatcga agactgtggc catgtcacta aaaatggctt tgaagtcttt
    23221 acccatactc caaaagagtt gctttatttt gaaggctaag cccctatcat ctggttaaac
    23281 aaaccctcgc gaaaggaagg tattcgtatg gatcaaacca ttcatcacca aatacagcaa
    23341 gcactacact ttagaacagc cgttcgtgtt tataaggaag aaaagatttc tgatgaggat
    23401 ttagccctta tccttgatgc tgcttggtta agtccttctt ctgttggctt agaaggctgg
    23461 cgctttgtcg ttttagacaa caagcctatt aaagaagaaa tcaagccctt tgcctggggg
    23521 gcccagtatc aactggagac agctagtcac tttattcttt taatagccga aaaacatgca
    23581 agatacgata gccctgctat caaaaatagc cttttacggc gtggtatcaa agaaggtgat
    23641 ggtctcaaca gccgcctaaa actctatgaa tctttccaaa aagaggacat ggatatggca
    23701 gataatcctc gggcactctt tgattggaca gctaaacaaa cctatatcgc tcttggtaat
    23761 atgatgatga cagctgctct tttgggcatt gatacttgcc ctattgaagg ctttcattat
    23821 gataaggtca atcatatcct agctaagcat aatgtgattg atttagaaaa agaaggcatt
    23881 gctagcatgt tatccctagg ctatcgcctg cgagatccca aacatgctca agttcgtaag
    23941 cctaaagaag aagtgatttc agtcgttaaa taaggagatt aaaatgaaag cattacatac
    24001 ctgtatccgc gtcaaagacc ttgaccagtc ggttgctttt tacacaagcg ccttcccttt
    24061 taaggaaaac tatcgtaaag attttccaga tagtcaattt actcttgttt atctggcttt
    24121 agaaggagaa agttatgaat tagaattaac ctacaattat ggtcatggcg actacgactt
    24181 aggaaatggc tatggtcata ttgcccttgg ctctgaacat tttgaagcag accataaaaa
    24241 acatcgacaa gcaggttttc cagttaccga tatcaaagaa ctggctgaca aatctgcccg
    24301 ctattatttc attcaggatc cagatggcta caaaattgaa gtcattgatt taaacaacta
    24361 atactattaa caacagaagc tttaaagctt ctgttgtttt attttttaac ctgacgattg
    24421 ggacaatctc attattaaca gagttttgaa atatctcagc ttttgtgtta caattgccct
    24481 aaaattccat ttgaaagaaa agtctatgac actactatct atcattgtcc cctgctttaa
    24541 tgaagaagca aacattctcc cttattttga agaaatgcat caactagaaa cgtccatgac
    24601 caaccaactt gcttttgaat acatttttat tgatgatggt tctaaggata acaccttggg
    24661 tattttgcgt gagctagctg ctcgctttcc aaatgtgcat tatctgtctt tttcacgcca
    24721 ttttggcaag gaagctggac tcttagctgg actaaaagaa gccaaaggca attacattac
    24781 tgtgatggat gtggatctgc aagatccacc cgaacttttg ccagttatgt acgctaagct
    24841 aaaagagggt tatgacatcg ttggcaccag gcgccaaaat agacaaggag aaccactaat
    24901 tcgttcaatg tgttcgaatc tattttatgg actgatcaaa cacttatcag atactgaaat
    24961 ggtcaatgga gttcgggatt atcggttaat gaccagacaa gtcgttgata gcattcttga
    25021 gttgggagag gttaatcgtt tttcaaaagg gatcttttcg tgggttggtt atcgtatcac
    25081 ctatcttagt tttgaaaatc aaaaacgcaa atatggaaaa agtcgttggc atttttggga
    25141 gttgctccga tattctttag atggctttat caacttttca gaaatgccgt taaccattgc
    25201 tacctggaca gggactttca gctttttgat ttctattttc gccatcttat ttatcattat
    25261 cagaaagata ctctttggtg atcctgtctc tggttgggcc agcactgtct ctattatttt
    25321 attcatggga ggcattcagc tcttttgcat gggtattatt ggaaaatata tttcaaaaat
    25381 attccttgaa actaaaaaaa ggcctctcta tattatcaaa gaaaaacatt aaattaaaac
    25441 atttttctca tcaatcgttt cctactcctt ctgtgcgcga agctttcttt ttaagcccgt
    25501 tataccaaat gataatgacc tttccaaaat agtatcactt tccttaacac tttaagtaga
    25561 aaaggaacta ttaggttgag cctttttgca aatcctagcg actaatgtta taatcgtcat
    25621 actattgaaa aaggagttct ttatggagtg gattaaatta atcggtattg tgattatcgt
    25681 attagggttt attttaaaat ttgatgctat cgctaccgta gttgttgcag gacttgttac
    25741 cgcgctggtt tcaggaattt cgtttattga ttttttagat attttaggaa aagaatttac
    25801 caatcaacgt ttgctaacca ttttcttcat cactttaccg cttatcggct tgtcagaaac
    25861 ttatgggctg aaacaccgag ctactcagtt gattcaacgt gttcaagccc ttaccgtcgg
    25921 ccgtttattg actctctacc ttattattcg agaattagca ggtctctttt cgattcgact
    25981 agggggacat ccacagttcg ttcgcccctt gattcaacct atgggagaag ctgctgctaa
    26041 agccaacatt ggagaagagt tgaccgatgc agaaaaagat gacatcaaag ctatggcagc
    26101 tgccaatgaa aactttggca atttctttgc ccaaaatacc tttgttggcg caggaggtgt
    26161 cctacttatc gctggaactt tagaacagct tggctatgat ggtaaccaag ctaaaattgc
    26221 attttcttct attttaattg ctattatctc tattattata gttgctattt acaattacct
    26281 ctttgagaaa aaaatggaac gtcaacatca gaaaggagat aactaatggc taacattgca
    26341 aaccttgttt tagaaacgat atatatcctt atcggcttgc aactgtttca cacagcctac
    26401 tgcaccttta aagataaaac caaccctgtc tattttggga cagctctgtt ctggggattg
    26461 ctgggtgtta ccttcgttgg cggtgccttt ttgcctaata aagttatcgg ttttatcgtg
    26521 attgtcctag ctcttttaac cttgtttaag caagttcgta ttggaacatt accagccttt
    26581 aatgaacaaa aagctgaaga aagtgctcac cgcattggta actggatttt cttaccagtt
    26641 atgttaatgg ctatgatttc tctacttctt gccttgatcc ttcctgattt cagtaaaagt
    26701 gccattggga ttgctggtat cttagccact attgctattt taataatcac taagcaaaaa
    26761 ccatctgctc ttttagctga aaataatcgg atgaaccaac aagtgtccac aagcggtatt
    26821 ttgccacagc tcttaggagc tttaggagct atttttgcag ctgctggtgt tggtgatgtg
    26881 attgcttctc tcattcggga gattgtacct gctgatagcc gcttctttgg tgttctcgct
    26941 tatgtgcttg gcatggttat ttttactatg attatgggaa acgcttttgc tgcctttacc
    27001 gttattacaa ccggtatcgg tgttcctttt gtttttgctt taggagctga ccctattatt
    27061 gccggtgctt tagctatgac tgctggtttt tgtggtacct tattaacacc aatggcagca
    27121 aactttaatg ccttgcctgt tgctttgatg gagatcaaag atcgaaatgc agttatcaaa
    27181 aagcaagctc ctatcgccct tgttttaatt attagtcaca ttgccttaat gtatttactt
    27241 gcttattatt aacttttttg ctaagttagt agcgtcagtt attcattgaa aggacattat
    27301 tatgaaaatt cttgtaacag gctttgatcc ctttggcggc gaagctatta atcctgccct
    27361 tgaagctatc aagaaattgc cagcaaccat tcatggagca gaaatcaaat gtattgaagt
    27421 tccaacggtt tttcaaaaat ctgccgatgt gctccagcag catatcgaaa gctttcaacc
    27481 tgatgcagtc ctttgtattg ggcaagctgg tggccggact ggactaacgc cagaacgcgt
    27541 tgccattaat caagacgatg ctcgcattcc tgataacgaa gggaatcagc ctattgatac
    27601 acctattcgt gcagatggta aagcagctta tttttcaacc ttgccaatca aagcgatggt
    27661 tgctgccatt catcaggctg ggcttcctgc ttctgtttct aatacagctg gtacctttgt
    27721 ttgcaatcat ttgatgtatc aagcccttta cttagtggat aaatattgtc caaatgccaa
    27781 agctgggttt atgcatattc cctttatgat ggaacaggtt gttgataaac ctaatacagc
    27841 tgccatgaac ctcgatgata ttacaagagg aattgaggct gctatttttg ccattgtcga
    27901 tttcaaagat cgttccgatt taaaacgtgt aggaggcgct actcactgac cgtgacgcta
    27961 ctaaacctat tttaaaaaaa cagagatatg aactaactct gttttttttg tgctaaaaat
    28021 gaaagaccta gggaaacttt tcatcggtct ttctcaattg tcatcttaat ctaatactac
    28081 ttctaacatc agcgggtata gtttgccagt aattaagaaa cgttgttgat ctaaatgagc
    28141 aatcccattc aaaacattaa ggtcagggta atgggactta tcaagattta aggcttttaa
    28201 caaaggacta atatcatagg tggctaccac ctttccagaa tcaggttgga gtttgacaat
    28261 agtattggtt tgccaaatat tggcatagag ataaccatct acatactcta attcgttaag
    28321 cattgagatg gggacacttt ctatagcaac tagtacggta tccaataaag caaaatcttt
    28381 ggggtctcgc ttttgcaaaa aagcatttcc actagtcatc caaagacact ggttttcctt
    28441 atcataggct aatccccagc catctccttc aaatggatag gcccctaaac aattgcaggt
    28501 agccttatca aacttgtagg ctacaccctc tttataggtt agtaaccaaa aataatcctc
    28561 aacaactgtt agcccttctg caaaaactgt atctggaaaa gctatttttt ctgaaaagat
    28621 ctcttgagta aggtcataca cccctacttt tgagaaacca taacgaccgg cactaagtaa
    28681 tatatgattg ttgttgagtt gttctaatcc ctgcgtgtat aagttgctat cataagaata
    28741 agttcgtaac aaacgaactt gtcctttagt tatcataata ctcattcacc ttaccttgca
    28801 ttgtagtgtt tcatttgttt tttaatatct ctttcctgat cacggcgttt aatggtttcg
    28861 cgtttgtcat actcgtgttt ccctttagct agaccaatca gaactttagc aaagccatcc
    28921 ttgaggtaaa ctttgagagg aaccaaagtc ataccagatc ctttaagttc atttgctaga
    28981 tgcgtaatct cacgtttttt gagcaacagt ttgcgggtcc gttcaggatc agcgttccaa
    29041 atattacctt gttcaaaagg tgcaatatgc acgttgacca accacgcttc cccattctta
    29101 atttgggcaa agccatcttt cagttgaata cgagctgcac gaacactttt aatctcagtt
    29161 cccgttaaga caatccctgc ttcaacggtt tcaacaatgt gataatcatg tctagccttt
    29221 ttattttgcg ccagtatatg accttcacct tttgccatag ttaactcctt ttacgactct
    29281 tcttttttgc ttgttctttg taaaatggtt ttttagaccc ttttttagtt ttacccttgg
    29341 tttttgcctt ggctacttct ttaggttctt ttttctttgt ccctttagat gattttgagg
    29401 atttacggcg atctcgtcga ctagctttat ccgacatctt gattttttca accacatcaa
    29461 agtcgctagg taaatactca aagtcaatgt caccagtttc cttgtcagcc ttaaccaatt
    29521 tcacacgaat aggttgacca actttaaaga ctttacctga tttttcacct tgaaggctta
    29581 gcgttctttc attaaagtga tagtattccg gtaagctagt gatatgaacc aaaccttcaa
    29641 tcgtatttgg caattctaca aaaaaaccaa atttaacgac actggccacg ataccgtcaa
    29701 attcttcacc cacatactct gccatatact cagctttttt catggcttca accacgcgtt
    29761 cagcatcaat agcacgacgc tctaactgtg aagaagatgt tgctaattct ggaatgatct
    29821 gagtaaaatg gtcgcgcttt tcttgactag gttgactgta ctcacgaacc atgcggtgaa
    29881 ccaacaagtc agggtaacga cgaatcggac tggtaaagtg agtgtaatat tctgcggcca
    29941 aaccgtaatg cccatgatta tgttcagaat atcttgcctg ttgcatagag cgtaagagca
    30001 tcatgttaag cacttctgct cctggttgac cttcgacttt tgccataaag gcttgcaagg
    30061 cttcctgaga aatcttgttg gctgttcctt gaatgtgaat accaaaggtg ctagcgtaat
    30121 caataaattg ttgaagtttt tcggcctttg gttcttcgtg aatacggtag ataaacggta
    30181 acttagcttt tgcaaaatgt tctgccacac actcattggc tgctagcata aaggactcaa
    30241 tcatccgctc tgcaattccc ctttgacgaa gcaccacatc aaccggcatt cctttgtcat
    30301 taacaataac tttagcttct tgcgtatcaa aattcaaggc gcctcgtttt gaccgcatag
    30361 cttccaaaat cctatgcaaa gccaccatga gggtcacatc atcagcaatg ctagcgaatt
    30421 cttggagcgc ttcttcatct cctgcaatca tgtcattgac cgtactatac gtcattcggt
    30481 aagttgtctt aatcactgat tgacagattt gataattgac cacatgccct tgagaattaa
    30541 tttccatcaa ggctgactgg gtcaaacgat caacgttagg gttcaaagag cagatgccat
    30601 ttgacaaacg ctctggtaac atcggaacca cacgatcggt gacatagaca gaagtgccac
    30661 gggcgatagc ttccttatca agggcagatc cttctgtcac ataatatgag acatccgcaa
    30721 tatgtacccc aagttcatag ttaccgttat ccaatagctt aatatggata gcatcatcta
    30781 agtctttggc gtccgcacca tcaatagtaa tggtggtttc ttgacgcaaa tccacacggc
    30841 ctattaaatc tttagcagtt ggtgcttctg aaatagcatt ggcctcagct aaaacttctg
    30901 ctggaaattc tgacacgata tccatcgatt caaggacttc taggacatca attccaacgt
    30961 ctccttgatg gcctacgata tcacgcacac tggctacaaa ataatcgtgc ccgcgtgtcg
    31021 ggtatttatc aatatcaacc ttgatgattt cagtgccttt aagcacaaca ggttcttttt
    31081 tgatatagat tttttgttga atcttttggt ttttggacct gatataacca gcatattttg
    31141 gtttgtcatc atctaaaata aaggttccaa cagctgtttt taaagaacgg tcaacaatag
    31201 caacgacctt agcttcagcc gctgtgcctt tgagacggtc tgctggcttt ttaaccacta
    31261 cttcgacagt atcaccatca atagcatacc caacatcatt acgaccgata aacatgtcat
    31321 cttcattctc atccacatgt aagaaaccaa agcctgcttt attggcacga aaaacaccct
    31381 gaacagtagg ttcttttttc ttttcacgct cttttctaag agccagactg ccatcatctg
    31441 aaaaccgtaa caggctctga ctttccattt tggaaatggt tttaataagg ctgggaaaat
    31501 gcttagctcc agccatctcc aaggccgcag ccaagtcgtt cacattggac ttgccatgct
    31561 ccttgaggta agtcataatt ctttctttca tcatacctaa tttctatttc tgttttgttt
    31621 gttggaggat atcaatccgt ttcgctgata aaaaaatgag ctagactaac tctgtcaagc
    31681 tcactcctta tttacttgat aaaatggcaa gcacaagtgc aatcgctagc caaaaaaata
    31741 ctagaactgc tgtgaatcgt tgcatgaatg cttcaaagcc acgagctttt gtacgttcaa
    31801 acaaggcttc tgaaccgctg ctatcaaaaa cattgctact tgggtttttt tgaggttgca
    31861 taaaaatagc aatcacaagc aataccgaca gtactagcaa tatcgtaagt agtaagttgt
    31921 acatgttatt tcctccacta ttgtcatgac cattctaaca caattcttat caagtttcaa
    31981 catgcagggt cacttttctc tccttggggc agtatttggg aacttttatt ttttccggat
    32041 gactgctttt atttttactg gttagataat tgttactgcc acactcacta cattctaaat
    32101 taatttttac tctcacacaa tatccttaac tttaatatat tttcgaaata taatcaaact
    32161 ccatattaaa ttaacaaaca caatcaaact agtcacataa aaaacagaac ggtagcctaa
    32221 cactacagcc acatttgatc cgataaaagg gccaatgact tgaccaaggt tactaaacat
    32281 ttgattatag gcaaatactc tagaaatacc ttcttttggt gttaacttag ttagtaaaga
    32341 gttaatactt ggcatcaaag cgcccacacc aaacccataa gcaaagcgta gtactcctaa
    32401 ttgaaaactg gtctgcgcta aggcactgct aaaatacatg ataaagctat aacacaaagc
    32461 ggctaacaat aaccgatgat tgccaaaacg atctcctaat tttcctaagt aagaactgct
    32521 aaataagcta gaaaacccca tggccgaaac taccaggcct gaagtaaaca ttaagttgtg
    32581 agtttgacca agatgacgaa tatacaatga taaaatgggg gccactgatt gagctgaaat
    32641 ttgaataatc atactagtca caaacaaacc aagcataatc tggggacttt ttacctgttt
    32701 taaaatgact tttgtaggta tcatctcaaa gcgcctaatc ggcttaaact cttctttaac
    32761 ataaacagct gtcattaaag aacataaaaa taatatcaca ccaactaata agaaaacttg
    32821 tcgaattcct aatagctctg ccaaaatccc ccctagtaaa ggaccaatta aagcgcctgc
    32881 tgtcactcct gttgctaatg tgcctaaagc ataacctgac tcctcttttg gggcttggct
    32941 ggcaatcaag gcagtggcat ttggcacata gcccgcaaag acacctgtta ataatctcaa
    33001 aatgagtaac caaaacacat taggaataat agctaaacca cccatggtaa aggtcatgac
    33061 aaaacttgct cgcagcatca taggttttcg gccataacga tcagccaact tcccccaaac
    33121 aggagcaaat aaagctgaag caagtgccgt cacagcaacc gccagaccag catagtattc
    33181 tactaattct ttcggagtac ctaaattttc cacatacaga gccataaaag gcataacaag
    33241 tgaaaagctt gccccagtaa agaagttacc aagccaagcc acttttagat tttgccgcca
    33301 gttcactgtc gttaccgctt tatcactaat agatcatcat cttctttcca tcgggccttt
    33361 gattattata acacatttct gccaaaaaca gtgtcccata atagtgctaa gtctcatctg
    33421 atagccttca tcgtttacgt aagctaccca gtaaacctct gaccagttct cgcccaattg
    33481 ttctaaccgt cgtactaata aacgcatctg ttgctttttc gacgactgtt tttcgtggac
    33541 gcccaacaga acggcgacta gcttttttgg tagctgcttg cgccttgatg gcttctttag
    33601 cttctttttc gcgttttgct gtcgctatcg cttcttgggc cagtcggttg tcttctaaaa
    33661 ccttagcagc taatttttca taagcagatt cacggtcaat ggactgacta tatttactgg
    33721 caaaaggtga agactgcaca agctgctgac tttctatctc tgacaaaaca gcaaagctac
    33781 tcttaggcgg catgatatag gcacgttcaa cgatggatgg ttgtccctta tcattcaaaa
    33841 cagaaatcaa ggcctcaccg acttctagtt ctgtaatcac ccttgccaca tctaagtcag
    33901 gattttgtcg gaaagtatcc gcagcgacac gaaccgcctt ttgttctttc ggtgtataag
    33961 cgcgcaaggc atgctgaata cgatttccaa gctgagccaa aaccgtttct ggcaaatcaa
    34021 gcgggttttg agtcacaaag aaaatcccaa ctccctttga acgaataagt cgcacaatct
    34081 gttcaacttt ttccaaaaag accttaggag cgtccttgaa caataggtga gcttcatcaa
    34141 aaaagaaaac catcttaggt ttgtccaaat ccccaacttc tggcaataat tcgtacaact
    34201 cagacaagag ccaaagtaag aaggttgtgt aaagggtagg agattgaaaa agcttagtcg
    34261 ctgacaaaat gttaatggct ccataacccg aagcaacatc taattgcatc aaatcagcca
    34321 catctaaagc aggctctcca aaaaattggt gggccccttc ttgttctaat gtcaagagac
    34381 ttctttggat agtcccgata gattgcttgg cgatattacc gtaatggctg gagtagtctg
    34441 aggcatggtc accaacttct tttaagatag cctgcaagtc tttcaaatca atcaaaagcc
    34501 aacctttctc gtcggcgatt ttaaagacga tgtttaagac acctgtctgg gtatcattaa
    34561 gattcaataa acgcgacaac atcatcggtc ccatttcaga aattgttgtc cgtaagggtt
    34621 gaccgttttg accaaaaaca tcccacattc ttacaggaaa ggcctgaggc tggtaatcac
    34681 ttaccccgat tgtggctaaa cgcgcagcca atttatcagt cacctctcct gctttagtaa
    34741 gattagacag gtctcctttg atatctgcca aaaagactgg cacaccagct aaacttaatt
    34801 gctctgctag cacttttaag gtcacagttt tacctgttcc agtcgctcca gcaatcaaac
    34861 cgtgacgatt tagcatccct aattgtaagg ctatcggttg actgcctttt gcaattgtca
    34921 ttgtagtcat aggcttcctc ttttttgatg atcatacttg tcgatatgtg tttacccata
    34981 agttaaagtg tttagaaggg tctcactctt aatactatta taacatataa cccttgatgc
    35041 gctaatttaa aagggaccag ctagttttag acagaaatag cttgattttg acagctatga
    35101 tacgaatctc tcagcttagc tacctcggat tggctaatga caacaacgca gattgtactt
    35161 gctttattaa ggctgcaata tccccactat tatcaatcac tagactggca tagggctttt
    35221 tttcctctat tggtaactga ctggctattc gctgccttgc ttttcctttg tctaaacgat
    35281 ttctagccat taagcgctgc aattgtgtct gagcatctac ataaaccagc caaatcgcat
    35341 caaaccagtc ttggtagccc aattccatta aaatgggaat atccatgaaa aaaatggctt
    35401 ggctctgtgc taagtggtca cgcttagccg ccaattcttc cttaatgatt tgattttgaa
    35461 tggctgagga tgttgccata ttatctgggt ttgaaaaaag catttctgac agctttgtgc
    35521 gatctaactc accatctgct tttaaaatct gattcccaaa agcttctcta agagcctcgt
    35581 aaagacgacc gcctttttct tgcaagtcat ggaccacttg atccgcatca atcacctgat
    35641 aaccagcttt tctaatgacc ttaaccacag tcgattttcc tgatgcaatg cctcctgtga
    35701 tgccaataat catggtcttt ttttctggca ttttggacaa atgtgcgtcc cccttcctcc
    35761 aacttttaat ttgacaatag cctgtccaca acgaggacac ggtttcccag tttgaccata
    35821 aacctgcaaa tagtcctgca tggtgccatc agctcccaaa gcattacggt aagtacggac
    35881 ggtcgaaccg cccttttcaa ttcctaaagc taggattcgt atggtttcat catgcagccg
    35941 ttttatctcc gccttattca acctagaaga cgcagttcct ggatgaacct tagcagccca
    36001 aagtacctcg tccacataaa tattccctaa accagcaacc aaggtctggt ctaacagatg
    36061 tggttttatg ggtttttggg aggatagcag agcagcctca aaggttttta acttaaaggt
    36121 ctctttcttt ggttcagggc ctagttttcg tttggcaaaa aacgctgata attgagattt
    36181 tgctatcaaa tcaaaggttc caaatttacg cacatcttgg taaaccaagg tcgaaccatt
    36241 tttcaattca aaaaagacat gaaagtgttt gttatcaggg acctcatctg gaaaaagcaa
    36301 atatttgcct tccatccgca aatgtgatac caacactaat tgccccaaat caattaataa
    36361 atattttccc cgacggccaa ctgactgaat gatttgacca ggtagggtca gggcaaacgt
    36421 ctctaagtcg gttttaacca tctttggcac tttaagcgta acagccacaa tttcttggcc
    36481 aagcactaaa gtctcaagcc ctcgtcggac cgtttcaact tctggtaatt ctggcataat
    36541 ccgttattta aaggacagct agaccctttg ctcctacaaa gaataaactc agtataaaaa
    36601 agtcactcaa tagactcagg tctaggctat tgactgcgtt tcaaaaaaca cagctgtcct
    36661 tctcctttct tatttcttat tttacgaaca catctgatag aaagcaactc ataaatctgc
    36721 ctcagaccag tcctcatccc ccttacctcc cagcactatt tggcggtaat gttccttata
    36781 actataatac aatgagtcct ctccaagata cttaaaaatc tgcaaggcct gccgcatgtc
    36841 ctcttctcca gacatttctt cctgctttaa tttataatac ccatgcacat ataagaaaac
    36901 agtcttttca taaaaattga gctcgtctcg cagcaaaaga tcaattttgt taatcaaata
    36961 gcgactatgt tcaaagcaag aatggtcaat actgataatg agacaattaa tggataactg
    37021 agtcactaac attttattgg ttttattttg ttccgaataa gcaaaagatg ctaccatttc
    37081 cttagtcaat aaaaataggg tattgtaatt catgaagcgc gagcaattcc ccagaagaat
    37141 gatttcataa tatccccact gttccacttt aaataaataa tctgtgaggc gagtcaattc
    37201 ttcttgacta ggtgcaattg aggagtcaat agaaaaaaga atagctttaa tcatcgttcg
    37261 ttcataatct ttatgggcat aatccttcaa cagtttggtc aatttaacca cgtttttctc
    37321 agcataacat tttctcgcct gacttaagag cgtgaaaaaa tgcgtatgcg tcttggaatg
    37381 agccgaaaca aattcgtcaa tcgtaatatt cagtttatcc aaaagattaa gcaagcgact
    37441 gcaggtgatt tctgattccc ctcgttcaaa tcttgaaatt tgtgacttgg acaggtattc
    37501 atctgctaaa aaagaaatgc taacctgctt acccttacgt aatcgcctta aggtttttcc
    37561 gagttctttt tccatttttc ccactttcac aacaaaaaat taaaatctgc taaatccatt
    37621 atataataca agtacaaaat agaaaatcag aaaggagaca gtcatgaaaa aagttaataa
    37681 agctttgctt tttacattga tcatggatat cctgattatc gttggtggat aacctttcgc
    37741 ttaaaaacaa tccacttttg ggaaaccctt atatttagtt tgtaacagga aaactaataa
    37801 atattaaaaa gagtgttagc gacctagcgg cagctttact cttaagtgcg tttgctgcca
    37861 ttgacagcaa ggtcaaagct aatgaaacag caggagcata ccgttatgat gtgtctgaac
    37921 aaaacactta ctatcaaact atcagctcca ttaaccagca acgacctggt gccactctcg
    37981 acgaatgagg tgattattat ggaaccctta cttcatttac ttcccaaaat cgtaccagta
    38041 cttatacact tggtagacaa agccaacgta tcatggttaa cagtgatatt acagttacct
    38101 atactcttaa agacaatttg gtagcccttc ataaggaata taaaaccttt gtcaaaaaaa
    38161 tattacagat aaaccgatca ccagtgacta cgacaaggct aaggttattt ataaccattt
    38221 actcaacgaa tacacttacg ccacaaaata acttagcacc aatcacaaaa ccgtaagcag
    38281 catcaacaat catactccta aagctcttta tcgtggcaag tgtggtgttt gtcaagctta
    38341 tgccgtcatg tttaaagata tggcagaagc tgcaggctta tcagcttggt atgtgataaa
    38401 aaaggattga atgagcacca tgcttgaaac atcgttacca ttcatggtgt taattcctac
    38461 gttgatgcta cctggaatga ttcagcatac accacaaggt atttccttgc tggaaaagac
    38521 gtgatgaata ctgagtaccg tttagatagc cagtacaacc acttggctaa tactatttta
    38581 actaccagct accaaaaagg ctaaactaac aacaactaca tttttcaact agaaaggcct
    38641 aaacaatgac caaaaaacag ttttatctta tcttagctat tagcatactg tgttttattc
    38701 ttgccgtcag ccctaaacca ccaattccta aacacactat tgaaaggaaa aggactgcga
    38761 tgaccatagg ccactcaaaa caaacccctc acaaaaaaga agcccttaaa cacaaaaaaa
    38821 acaaaaataa ggctctattt cttccaagtg gggacagcgc tatcaaatct gttattagca
    38881 tgacagttag actcctgtta gatgaccaat attagctctc ctaaaatcag tggacactac
    38941 catttcggta gtgttctttt ttaagctaat ctcatcacca cgctttcttc aagctaaaaa
    39001 actgatcatg aaagagcaac cccatcaccc taacagccca ctttgcccgc actttcttaa
    39061 aaagttagga gaaaacgata taccaattat tttctgatcc cagctcccta tcattaacaa
    39121 gatgtgtagc acggacctac atacaggtaa gctagagtca ttctcgctac ttcggacaaa
    39181 aagaggccgg tagttccctg acctcttctt tatttatctt gtaacactcc tcttcttagc
    39241 gagacttact agcacataat tcttaagcac tcttatcatt tagactagga ataacaccat
    39301 ctgaatgaag caaatgatgc gtcagatctg ccagagtatc atctccataa gtaatccctg
    39361 tttggtgctg tttctgatga aaatcagatg actccttaac tttagcagtc acctgctggt
    39421 cacttggatg aaaattaatt tctctcttgg cttcagccgc aactggctcg aggaacaact
    39481 tattgacatt acggtcttcc tccaaatgat taaggatagc agcatcatct tctaacgaaa
    39541 gaaccttctt gggtaacaaa aaggggttat ttagccttgg ctcagtaacg acttccttgg
    39601 ctactcgtga tagtttatta ttgtcttcct caggtatcaa acggttaggc aatcgatgca
    39661 attcttccgg ctatgaggcg ctcacagcta cttcagaaga aacctccaag ccctttcctg
    39721 tttgcctgtc taactaaagc aaccggcaaa ttattaacta actttttaac ctgtcctcag
    39781 cgctcatttc aacactagga agagctgtcg ctggttctag ccagctacca acttctgctg
    39841 gtcttacctt aacatcgctg gcaggcttct ccttctcatc ttcattaggt ctaaaaggct
    39901 caaaccgccc tgttgatttt tcatctatga cctttatatt gtcttttact acatgagaca
    39961 gtggttcgac atttaccata gcttcatgct cgttaaggct ctggtctcgt ttgaatttac
    40021 caggaatacc aggagtcggt gttccgacag attgatcggc ttcagtaggc tcttttacgg
    40081 agcctttttc ccataacacc gctgatggaa tgatatccgt agagccatct ccgtaaataa
    40141 tcgtggcctg accacctctt ggattaatag ataccttaat attgtctggg aaagccccac
    40201 tacttcctgt ggttaaaagg gcacccgcat ttttaatgag agttgtcatt cgttcaatac
    40261 cagcaacgcc aatatggttc aagtcatcta ctggtaactg atcaacagat ttcatggtgt
    40321 atttccaagc ttgcggttga acaagaaaaa cagttccttt atacattgtg ttatgcatat
    40381 catcaatgac tttgaaatac cttgtatatt tggtttgtac attagggtta gcaacgggaa
    40441 cagtgctttc aggaactcct gacatcgtaa aaatccctct agcagaagtt tgaaagccct
    40501 cataaacatg acccatacca ggaacagtct gagcggtcaa agacttacca gaaccatcca
    40561 aagcaatgcg aatatctttc atcagataca tctgattggt gtaggtaaac ctaaccgtgt
    40621 tagcctcacc tcgatacaaa accacttggg agggctgatc cgaagaaaac tgagaggttg
    40681 tttcttcctt atagccaact ccaaaacgtc tatcagacga atggactgaa tctgccgcaa
    40741 ctgtactact caaactgact agtaaagtag ccgcacaacc aactaataaa ctgctcattt
    40801 taactttaac atctcttaac atcatcatgt tcctttcatt attttttatt taggaattcg
    40861 tcatactata ttttctcata ttagtctaac aaaaaacccg taattctata taaatcatat
    40921 aaaatgacga gctttggcaa agatgagtat agcaggatgg aaaacagatt gtttctgaaa
    40981 cttcaaaggt atcttcttgt cacgaactat tctttaattg a
//
LOCUS       DATWEK010000014        37485 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.014, whole genome shotgun sequence.
ACCESSION   DATWEK010000014 DATWEK010000000
VERSION     DATWEK010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37485
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.014"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            34..1530
                     /locus_tag="VCR92_000895"
     CDS             34..1530
                     /locus_tag="VCR92_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEP4267978.1"
                     /translation="MQQSMTKVKYLWKENNNYIYSTFLTLLLTVILYANSLNLPLKFI
                     SLLFVVSTLLIVFLPKKLEVATIIFILVFGTISAIISPINDIPDEYVHYSRTVYISEG
                     DINLTNNNKKLRISKDVDKLIKQSGKTFITSNLKATKHSTREYSYPYIKGTNAYYSFS
                     YIPQALGILVGNALDLPILLTYYFGRLCNLISYAMLAFIAIKLSGSFKQVIAVVTLLP
                     MNIYLAASFNQDGFAIGLVLVTIGLFINLLSSKDKSNYNTKFFLYLVLCGLLVLSKFT
                     YFLLVCLPLFIPNEKFGKNTKLVILKKLGGLLLIFLFAAMWFRLYGQVKTPYVADFLK
                     EVNVSQQVKNMLESPIVYSSIIIRHMVINLINMNNIFQFGALSYGITNLFPLYVCFFF
                     FVYISNASKITINIVEKMGIIFVISAIIGATVLAMYLTWTPVGSSTVLGVQSRYLIGI
                     IPLVLLLFSSQQQKFKQIEDILSDKLAIHVSLLFILAMLMSTIFRYYH"
     gene            1624..2847
                     /gene="pepT"
                     /locus_tag="VCR92_000896"
     CDS             1624..2847
                     /gene="pepT"
                     /locus_tag="VCR92_000896"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEP4267979.1"
                     /translation="MKYDNLLDRFIKYVKVNTRSDPDSETTPSTESQEAFALTILKPE
                     MEAIGLQDVHYNPVNGYLIGTLPANNPTLTRKIGFIAHMDTADFNAENVNPQIIDNYQ
                     GGDITLGSSNYKLDPKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIEFLTS
                     QPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALE
                     VTFLGRNVHPGTAKDQMINALELAIDFHEKLPAKERPEYTDGYQGFYHLTGLTGTVEE
                     ARASYIIRDFEEASFEARKVKVENIAQSMNAQLGTKRVLVELNDQYYNMKKVIEKDMT
                     AIELAKEVMEELAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MERAVDVIIGLVCKA"
     gene            2888..3376
                     /locus_tag="VCR92_000897"
     CDS             2888..3376
                     /locus_tag="VCR92_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEP4267980.1"
                     /translation="MIKLFGKIRYHWQPELSWSIIYWSIAFAPIFVGLSLLYERTEIP
                     SRVFILFAIFAVLVGIGLHRYFIIENNGILRIVSFKLFGPRKLLISTITKIEVTKSTL
                     CLHFEDKSYLFYMRKWPKKYFLDALAVNPYFQGEVILSDNFIKLDYFEVYQHDKKALT
                     RG"
     gene            complement(3363..3560)
                     /locus_tag="VCR92_000898"
     CDS             complement(3363..3560)
                     /locus_tag="VCR92_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEP4267981.1"
                     /translation="MKVSIIPEKCIACGLCQTYSSLFDYHDNGIVTFSSSSETSQSIC
                     PSDKDAILAVKSCPTKALTLE"
     gene            3609..4085
                     /locus_tag="VCR92_000899"
     CDS             3609..4085
                     /locus_tag="VCR92_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEP4267982.1"
                     /translation="MAKEPWEEKIVDDTIGTRTRKSRNAFISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNRQAETNGFYGASTHKKTRKASNAKKASSSSTTTDTTPSSEETL
                     ASSEGTGETLTVLAGEGAASIAARAGISVEQLQALNPEHMTQGYWYANPGDQVTIK"
     gene            4100..4780
                     /locus_tag="VCR92_000900"
     CDS             4100..4780
                     /locus_tag="VCR92_000900"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEP4267983.1"
                     /translation="MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALTHGYTGKEVALILEELEKNPISFKKAKDGSQLVFLGDEDVTLAIRQNDVTNNVSWV
                     SALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKE
                     NLEKGIESDFETLKEEIAARDYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEK
                     AEKIVDMS"
     misc_feature    4804..4927
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            4942..5472
                     /gene="infC"
                     /locus_tag="VCR92_000901"
     CDS             4942..5472
                     /gene="infC"
                     /locus_tag="VCR92_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEP4267984.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     SNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     gene            5514..5711
                     /gene="rpmI"
                     /locus_tag="VCR92_000902"
     CDS             5514..5711
                     /gene="rpmI"
                     /locus_tag="VCR92_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEP4267985.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGLVSSGDFKRIKAMVTGL"
     gene            5770..6129
                     /gene="rplT"
                     /locus_tag="VCR92_000903"
     CDS             5770..6129
                     /gene="rplT"
                     /locus_tag="VCR92_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEP4267986.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVAD
                     AAAFTALADAAKAKLGK"
     gene            complement(6420..8630)
                     /locus_tag="VCR92_000904"
     CDS             complement(6420..8630)
                     /locus_tag="VCR92_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEP4267987.1"
                     /translation="MTSLGKNDKEVATVKKFKTLITGFINTRLGFIITLLFCYWIKTL
                     WAYHTDFSLDLGNIYQVFLTIINPIPLAFLLLGVALYVKNTRAFYICSWVVYIILNIL
                     LISNSIYYREFSDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSIT
                     KKIKNDQRPFNKRAAFAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRALGLPA
                     FTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHYAAPDPQYFGIGKGKNIIVLHLES
                     FQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPNFFHQVKAGKTSDAETMMENSL
                     FGLNSGSFMVNYGGENTQFATPSILTQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYF
                     FDSSYFSKQNSKNSFQYGLNDKYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGE
                     SSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLYENSIFVLYGDHYGIS
                     NSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALPTLL
                     HILGIDTSQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLYNTQTGLEITNP
                     DEMTIAKTKEIRSAVAQQLAASDAIQTGDLLRFDTQNGLKAIDPNQFIYTKQLKQLKD
                     ISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNPKNKE"
     gene            8738..9901
                     /locus_tag="VCR92_000905"
     CDS             8738..9901
                     /locus_tag="VCR92_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEP4267988.1"
                     /translation="MNKLYIDSFVEKKLTAGVQLLDEKDFSNIKEKNQLVQLVTKSNR
                     PIGTAYISKQNKGIGWYLGPEKIDLSISYFVSLFSVAKAKRQDFAQSDETNAYRLFNQ
                     EGDGFGGVTIDLYKDFAVFSWYNAFVYDKKEMIMEAFQQVFPEVKGAYEKCRFKGPDT
                     ETAHLYGELAQETFSILENGIAYQVFLNEGLMTGVFLDQHDVRRALVDGLAMGKSLLN
                     LFSYTAAFSVAAAMGGAIETTSVDLAKRSRELSLAHFEHNQLNLASHHFVVMDVFEYF
                     KYAKRKKLIFDVIVIDPPSFARNKKQTFSVSRDYHKLITEALDILSPKGTIIASTNAA
                     NMTVSQFKKQIIKGFGSRRPESMTLQQLPSDFTINKADERSNYLKVFTIKVRE"
     gene            9898..10584
                     /locus_tag="VCR92_000906"
     CDS             9898..10584
                     /locus_tag="VCR92_000906"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEP4267989.1"
                     /translation="MRIVAPVMPRHFDEAQAIDISKYEDVNLIEWRADFLPKDEIVAV
                     APAIFEKFAGKEIIFTLRTVQEGGNITLSSQEYVDIIKEINAIYNPDYIDFEYFTHKS
                     VFQEMLDFPNLILSYHNFEETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATISMGKLGRLSRFAGDVIGSSWTYVSLDHVSGPGQVTLNDMKRI
                     IEVLEMDISN"
     gene            10678..11844
                     /gene="aroC"
                     /locus_tag="VCR92_000907"
     CDS             10678..11844
                     /gene="aroC"
                     /locus_tag="VCR92_000907"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEP4267990.1"
                     /translation="MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYG
                     RGARMSIETDRVQISSGVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRR
                     VKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHH
                     ILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGII
                     ETIVQGVPAGLGSYVQWDKKLDAKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEI
                     TWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKAT
                     VERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF"
     gene            11905..12246
                     /locus_tag="VCR92_000908"
     CDS             11905..12246
                     /locus_tag="VCR92_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEP4267991.1"
                     /translation="MSQEIYDYANQLERAVRALPEYQKVLEVKEAIQADASASELFDE
                     FVAMQEKIQGMMQSGQMPTAEEQTSIQELSQKIEANDQLKAYFEAQQALSVYMSDIER
                     IVFAPLKDLVK"
     gene            12468..13820
                     /gene="gorA"
                     /locus_tag="VCR92_000909"
     CDS             12468..13820
                     /gene="gorA"
                     /locus_tag="VCR92_000909"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEP4267992.1"
                     /translation="MVIPYDYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGTCVN
                     LGCVPKKVMWYGAQVADILGTYAKDYGFDFKDKAFDFKQLKANRQAYIDRIHASYERG
                     FEQNGVDRIYDYAVFKDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGAQYGISSDGF
                     FALDEVPKRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKAIVDVLVEEM
                     AVGGPCLHPHSEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEGFGLDKTG
                     VTLNDKGYIETDAYENTSVKGIYAVGDVNGKLALTPVAVAAGRRLSERLFNGKTDEKL
                     DYQNVATVIFSHPVIGSVGLSEEAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMK
                     LVTVGDTEKIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR
                     "
     gene            complement(13908..15176)
                     /locus_tag="VCR92_000910"
     CDS             complement(13908..15176)
                     /locus_tag="VCR92_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEP4267993.1"
                     /translation="MTTYDSISWIHTFKANGRKTDLARMAWLLEALGRPQDKFPAIHV
                     VGTNGKGSVTAYLQHILSTSGYQVGTFTSPFIISFHDRICLNGQPISDLELAQCVSVI
                     RPILTKMSLETNWDRPTEFELVTLIMFCYFANLKPVDIAIIEAGIGGKTDATNVFHAL
                     AVVCPSISFDHQERLGYSLAEIAHQKAEVIKAKEPVIIGQLEQEASQVFQQVTQKAGS
                     RLYQLGKDFLLNPSEKTFSFQHDNLNLTKLRLKLLGQHQKANACLAIMTAQLLRKSFP
                     KISPKTIQKGIEATTWPGRSEFIQPNLLLDGAHNPDSIAKLKSLLQEEFPKRPIHILF
                     AGLKRKPLADLLAQLDTFEVSVTTFDFPEANLLEDYPDKYPQVKDYRDWLQGSVTSDE
                     LFVVTGSLYFISEVRQYCLSNANIFKNIFP"
     gene            complement(15206..15646)
                     /locus_tag="VCR92_000911"
     CDS             complement(15206..15646)
                     /locus_tag="VCR92_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4267994.1"
                     /translation="MSSRYSRQQKPRKSGGVPTEHIKTGFTAFQKSIALIGSILSIIV
                     ATITITRALQPVPDKTSNDTPKESSNTIVKIIEKESSQGNQNHTGTSETTDDNKTTLP
                     SSSTTPSHNETTPTAPETPSATEGTQLPNATGAEDANTGLPTNS"
     gene            15881..17023
                     /locus_tag="VCR92_000912"
     CDS             15881..17023
                     /locus_tag="VCR92_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEP4267995.1"
                     /translation="MIYFDNAATTIPYGEALKTYQEVATKIYGNPSSLHQLGTNASRI
                     LEASRKQIAGLLGVKSEEIFFTSGGTESANWAIKGIAFEKTAFGKHIIISAIEHPAVS
                     ESVKWLLTQGFEVSYAPVTTQGVVDVNALAELIRPDTILISIMAVNNEMGAIQPIRAI
                     SNLLANQPTITFHVDAVQAIGKIPLCDYMTNRVDLASFSGHKFHSVRGVGFLYKKAGK
                     RLNPLLSGGGQEQELRSTTENVAGIASMAKALRIVTEKQVSVLPKLTAMRDVIYKALS
                     AYPDVTVFSAQEGFAPNILTFGIRGVRGEVIVHAFEKYEIYISTTSACSSKAGKPAGS
                     LVAMGIPVKTAQTAVRISLDDDNDMGQVEQFLTIFKQIYDKTQKVR"
     gene            17035..18249
                     /gene="thiI"
                     /locus_tag="VCR92_000913"
     CDS             17035..18249
                     /gene="thiI"
                     /locus_tag="VCR92_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEP4267996.1"
                     /translation="MDYSEIMVRHGELSTKGKNRMRFINKLKNNIQDVLAPFPAIAVR
                     SDRDRTHVSLNGTDYQPIVEALKLVFGVQALSPVYKLEKSVPLLVTAVQDIMTSLYRD
                     GLTFKIATKRSDHAFELDSRELNSLLGGAVFEVLPNIQAQMKHPDVTLKVEIRDEAAY
                     ISYEEIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGLDIEVVHFASPPYTSPG
                     ALAKAQDLTRRLTRFGGNIQFIEVPFTEIQEEIKNKAPEAYLMTLTRRFMMRITDAIR
                     EQRKGLVIVNGESLGQVASQTLESMQAINAVTSTPIIRPVVTMDKLEIIEMAQAIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLGNAEKYEERFDIDGLVQRAVSGIVVTEITPEIV
                     NDEVENLIDALL"
     gene            18287..19579
                     /locus_tag="VCR92_000914"
     CDS             18287..19579
                     /locus_tag="VCR92_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEP4267997.1"
                     /translation="MILLKSLYKGFFAAMKEENFEARCYNREKGGCVLIKTMQYKKTM
                     ATVVALIVALLLFGLIYDLLGVQKNKLAAQKSAQPKVKTARVVANGDILIHDILYMSA
                     RKADDTYDFTPYFEYVKDWISGADLAIGDYEGTISPDYPLAGYPLFNAPEEIAGALKN
                     TGYDVVDLAHNHILDSQLDGALNTKKVFHQLGIDSIGIYDKDRSKESFLIKNVNGIKI
                     AILGYSYGYNGMEATLSQEDYEKHMSDLDEAKIKKELQLAEKKADVTIVMPQMGTEYA
                     LEPTAEQKELYHKMIDWGADVVLGGHPHVIEPSETVIKGRQKKFIIYSMGNFISNQRL
                     ETVDDIWTERGLLMDLTFEKKDNKTKIKTVEAHPTMVLAKGKGIVGKEGFELYNYRTM
                     VLEDFIKGGKYHDKIDEETKAKVALAYQEINDLVNLKW"
     misc_feature    19684..19758
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            19793..20107
                     /gene="rplU"
                     /locus_tag="VCR92_000915"
     CDS             19793..20107
                     /gene="rplU"
                     /locus_tag="VCR92_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEP4267998.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEVTFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            20119..20445
                     /locus_tag="VCR92_000916"
     CDS             20119..20445
                     /locus_tag="VCR92_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEP4267999.1"
                     /translation="MIKAIFTRQKNGQLSSVTLTGHAGSGKHGFDIVCASVSTLAINF
                     VNSLEVLADCQALVDLNDVEGGYMAITIPPHDNKEEVQLLFESFLLGMTSLAKDSSKF
                     VNTQVI"
     gene            20473..20766
                     /gene="rpmA"
                     /locus_tag="VCR92_000917"
     CDS             20473..20766
                     /gene="rpmA"
                     /locus_tag="VCR92_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEP4268000.1"
                     /translation="MLKMNLANLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPVAK"
     gene            21124..22038
                     /locus_tag="VCR92_000918"
     CDS             21124..22038
                     /locus_tag="VCR92_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEP4268001.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELG
                     FQIFNRTTSGTVLTSQGLVFYEKALEVVKSFDSFEKTFSQADLDQNEFSIASQHYDFL
                     PPLITAFSQQYDGHRVFRIFESTTIQILDEVAQGNSEIGIIYLNVDNQKGLFQRMDKL
                     GLEYVSLIPFTTHIYLSKTHPLANREALYLSDIQGLPAVRFTQERDEYLYYSENFVDT
                     SECPRIYNVSDRATLNGILERTNAFATGSGFLDHRSVNGIKVIPLADHIDNQMIYVKR
                     KDKNLSVAGATFVTILKDYFDKRRKALT"
     gene            22035..22493
                     /locus_tag="VCR92_000919"
     CDS             22035..22493
                     /locus_tag="VCR92_000919"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEP4268002.1"
                     /translation="MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLT
                     YLQNNGAAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGIGN
                     FIDRLRLAYVIDMVHLDFVDFAIFNVADSYLTVGVILLVICLWKEEDYGN"
     gene            22483..23373
                     /locus_tag="VCR92_000920"
     CDS             22483..23373
                     /locus_tag="VCR92_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEP4268003.1"
                     /translation="MEINVITSGQRLDKALADLSPLSRGQANDQIKQGLVLVNGQQKK
                     AKYTVQAGDVICFELPKEEVLEYQAQNIPLDIIYEDDTLAIINKPQGMVVHPSAGHPS
                     GTMVNALMYHIKDLSSINGVVRPGIVHRIDKDTSGLLMVAKTDAAHQALAEELKAKKS
                     LRKYLAIVHGNLPNDRGMIEAPIGRSEKDRKKQAVTAKGKEAVTRFTVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDPLYGPRKTLSGHGQFLHAKTLGLTHPMTGKEM
                     IFTVEAPEIFQKVLKLLRKK"
     gene            23768..24289
                     /gene="pyrR"
                     /locus_tag="VCR92_000921"
     CDS             23768..24289
                     /gene="pyrR"
                     /locus_tag="VCR92_000921"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEP4268004.1"
                     /translation="MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVF
                     LARRIQERLHQLEGLDLPIGELDIKPFRDDMRVEEDTTLMSVDITGKDVILIDDVLYT
                     GRTIRAAIDNLVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVE
                     VDGRDRVSIIDPT"
     gene            24305..25564
                     /locus_tag="VCR92_000922"
     CDS             24305..25564
                     /locus_tag="VCR92_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEP4268005.1"
                     /translation="MKDVIYDVEEVPKAGMLVGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTKFKIPAYMGSSFAYIAAMQLLMKTNGIGAVAQGAMTGGLVY
                     LIVALIVKVIGNDWIDKILPPIVVGPIVMVIGLSLASTAVNDVMLKNGNYNLTYLVIG
                     LVTLLSVIFFNIYGKGIVAIVPLLLGLLVGYVVALLVGVLTGQEIVDFTNVAQAKWFS
                     IPSVEIPFLTYGVKFYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGFAQIIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAALLSFIGKVSA
                     LIQSIPTPVIGGISVALFGVIASSGLKILIESKVDMDNKKNLLIASVILVSGIGGLML
                     QVNGLQISGVAFSTLLGIILYQVLPEK"
     gene            25625..26560
                     /locus_tag="VCR92_000923"
     CDS             25625..26560
                     /locus_tag="VCR92_000923"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEP4268006.1"
                     /translation="MSVVNNRVALTNLVSMEALTTEEVLGLINRGSEYKAGKVVISDH
                     QKDLVANLFFENSTRTHKSFEVAEKKLGLTVLDFNADASAVNKGESLYDTVLTMSALG
                     TDICVIRHPEDDYYKELVESPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGRFEGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEEWYSEAFNAYGTYIAIDQIIKELD
                     VLMLLRVQHERHDGHQSFSKEGYHQAFGLTQERYQQLKDSAIIMHPAPVNRDVEIADS
                     LVEAPKARIVSQMANGVFVRMAIIEAILNGRNKNS"
     gene            26604..27686
                     /gene="carA"
                     /locus_tag="VCR92_000924"
     CDS             26604..27686
                     /gene="carA"
                     /locus_tag="VCR92_000924"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEP4268007.1"
                     /translation="MTKRLLILEDGTIFEGEPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLIGNYGINRDDYESISPTCKGVVVSEVSRLASNWRKQMTLDAFLK
                     IKGIPGISGIDTRALTKIIRQHGTMKATMADDGDSIQHLKDQLRATVLPTNTIEQVST
                     KTAYPAPGIGKNIVLVDFGLKHSILREFSKRQCNITVVPFNITAEEVLQLNPDGLMLS
                     NGPGNPEDLPEALDMIRGVQGKIPIFGICMGHQLFSLANGAKTCKMTFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERSSLPDTLMVTHEDINDKTVEGVKHRDFPAFSVQFHPDA
                     APGPHDASYLFDEFLEMIDSWRCTSK"
     gene            27932..31108
                     /gene="carB"
                     /locus_tag="VCR92_000925"
     CDS             27932..31108
                     /gene="carB"
                     /locus_tag="VCR92_000925"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004218948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEP4268008.1"
                     /translation="MPKRKDIQKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYKV
                     ILVNSNPATIMTDKEIADKVYIEPLTLEFVNRIIRKERPDAILPTLGGQTGLNMAMAL
                     SKAGILDDLEIELLGTKLSAIDQAEDRDLFKQLMQELDQPIPESTIVKTVDEAVTFAR
                     DIGYPVIVRPAFTLGGTGGGICSSEEELCEITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPTQTLSDIENQMLRDASLKIIRALK
                     IEGGCNVQLALDPYSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEM
                     INPITGTTYAMFEPTLDYVVAKIPRFPFDKFEHGERQLGTQMKATGEVMAIGRNLEES
                     LLKACRSLEIGVCHNEMTSLSNISDEELVTKVIKAQDDRLFYLSEAIRRGYSIEELES
                     LTKIDLFFLDKLLHIVEIEQDLQMHVEHLESLKKAKRYGFSDQKIAEIWQKDESDIRA
                     MRHSHSLYPVYKMVDTCAAEFDAKTPYFYSTYELENESVQSNKESILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQKAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAQALSEAGVTILGTQVEDLDRAEDRDLFEKALKELGIPQP
                     QGQTATNEEEALEAAKKIGFPVLVRPSYVLGGRAMEIVENKEDLREYIRTAVKASPEH
                     PILVDSYIFGKECEVDAISDGKSVLIPGIMEHIERAGVHSGDSMAVYPPQQLSKQIQE
                     TIAEYTKRLAIGLNCIGMMNVQFVIKNEQVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKLILGQTLKDLGYEDGLYPQSQLVHIKAPVFSFTKLAQVDSLLGPEMKSTGEVMGSD
                     TSLEKALYKAFEANNSHLSEFGQIVFTIADDSKAEALSLARRFKAIGYQIMATQGTAA
                     YFAEQGLSACLVGKIGDAANDIPTLVRHGHVQAIVNTVGIKRTADKDGQMIRSSAIEQ
                     GVPLFTALDTAKAMLTVLESRCFNIEAI"
     gene            31315..32586
                     /locus_tag="VCR92_000926"
     CDS             31315..32586
                     /locus_tag="VCR92_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEP4268009.1"
                     /translation="MSKRGKIKITTKTKLITASVITLVLIITGVVLWKQQQNTLTADI
                     AKEPYSTVSVTEGSIASSTLLSGTVKALSEEYIYFDANKGNDATVTVKVGDQVTQGQQ
                     LVQYNTTTAQSAYDTAVRSLNKIGRQINHLKTYGVPAVSTETNKDEATGEETTTTVQP
                     SAQQNANYKQQLQDLNDAYADAQAEVNKAQIALNDTVVISSVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGQLQVKGTLTEYDLANVKVGQSVKIKSKVYSNQEWTGKISYVSNYPT
                     ESNAGSTTPAGSTGAGSSTGAAYDYKIDIISPLNQLKQGFTVSVEVVNEAKQALVPLT
                     AVIKKDKKHYVWTYDDATGKAKKVEVTLGNADAQQQEIHKGVAVGDIVIANPDKNIKP
                     DKKLEGVISIGTNTKPEKDSQSKNKKSGVDK"
     gene            32586..33296
                     /locus_tag="VCR92_000927"
     CDS             32586..33296
                     /locus_tag="VCR92_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4268010.1"
                     /translation="MSHEKKQLMQLSNIVKSYQNGDQVLKVLKGINLTVYEGEFLAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYTLHNTKIEILNDRELAKVRNDEIGFVFQQFFLL
                     AKLTALQNVELPLIYAGVNVSKRREQAKQFLEKVGLGRRIKHLPSELSGGQKQRVAIA
                     RALVNDPSIILADEPTGALDTKTGQQIMELLTELNKEGKTIIMVTHEPEIADFATRKI
                     IIRDGDITTDTTASVVID"
     gene            33308..34528
                     /locus_tag="VCR92_000928"
     CDS             33308..34528
                     /locus_tag="VCR92_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4268011.1"
                     /translation="MENWKFALSSIWGHKMRSILTMLGIIIGVAAVVIIMGLGNAMKN
                     SVTSTFSSKQKDIQLYFQEKGEEEDLYAGLHTHENNHEVKPEWLEQIVKDIDGIDSYY
                     FTNSATSTISYEKKKVDNASIIGVSKDYFNIKNYDIVAGRTLTDNDYSNFSRIILLDT
                     VLADDLFGEGNYKSALNKVVSLSDKDYLVIGVYKTDQTPVSFDGLSGGAVMANTQVAS
                     EFGTKEIGSIYIHVNDIQNSMNLGNQAADMLTNISHIKDGQYAVPDNSKIVEEINSQF
                     SIMTTVIGSIAAISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIES
                     VVLTVLGGLIGLLLAQLSVGALGNAMTLKGACISLDVALIAVLFSASIGVFFGMLPAN
                     KASKLDPIEALRYE"
     gene            34782..36515
                     /locus_tag="VCR92_000929"
     CDS             34782..36515
                     /locus_tag="VCR92_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HEP4268012.1"
                     /translation="MTFLSDLISLMTKIRLSWVIKAGIFQLLFVTIANIVLSEFFYFI
                     LDVTGQYHLDKDNVVTFLKNPIALALLGAYLFLLAAFIHLEFFALYRIIADQEISFYL
                     FRKQFSYYLRGLWKTFSGYQLLLFLLYILLTIPVLHIGLSSVITQKLYLPEFIVGELS
                     KITSTKYLLYGSLILVFYLNLRLVYFLPLIAINHRTVAQAWRESWQKTKKKHVLLWMK
                     LFAINGLTLVVVSLAISMILIFVDMFNPKGNNIIVQLGALTFTWELIFFTTIFFKLCS
                     AMILKEAIEPQKQYDEPRRSNKAYVVIFIVVTVGFAYQSLERLTFFDTSHSKTVIAHR
                     GLVSAGVENSLEALEGAKKAGSDYVELDLILTKDNHFVVSHDNRLKRLAGVNKTIRNL
                     TLKEVEHLTSHQGHFSGRFVSFDTFYQKAKKLNMPLLIELKPIGTEPGNYVDLFLETY
                     HRLGISKDNKVMSLDLEVIEAIKKKNPSITTGYIIPIQFGFFGDEFVDFYVIEDFSYR
                     SYLSSQAFWNNKEIYVWTINDPKRIEHYLLKPIQGIITDQPALTNQLIKDLKQDNSYF
                     SRLVRIISSLY"
     gene            36642..36914
                     /gene="rpsP"
                     /locus_tag="VCR92_000930"
     CDS             36642..36914
                     /gene="rpsP"
                     /locus_tag="VCR92_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEP4268013.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQITIKEDRVLEWLSKGAQPSDTVRNILSKAGVMAKFHDQKFSK"
     gene            36924..37163
                     /locus_tag="VCR92_000931"
     CDS             36924..37163
                     /locus_tag="VCR92_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEP4268014.1"
                     /translation="MDTIENLIIAIVKPLISQPDNLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
BASE COUNT        11881 a         6193 c         7730 g        11681 t
ORIGIN      
        1 ttattatgaa tagatttaag aagggaagag ttaatgcaac aatctatgac taaagttaaa
       61 tatctttgga aagaaaataa taactatatt tattcgactt ttttgacatt acttctgaca
      121 gttattttat atgccaatag tttaaatcta cctttaaaat ttattagtct tctttttgtg
      181 gtgagcactt tactgatagt gtttttacca aaaaagttag aggttgctac gatcattttt
      241 attttagtat ttggaacgat atctgctatc atatcaccta taaatgatat tcctgatgaa
      301 tatgttcatt attcaaggac agtttatatc tcagaaggtg atattaatct taccaacaat
      361 aacaaaaagt taagaatatc caaagatgtt gataagctta ttaaacagtc aggaaaaaca
      421 tttataacat caaacttgaa agcaactaaa cacagcacaa gagagtatag ctatccttac
      481 atcaaaggaa ctaatgcata ttatagtttt tcttatatac cacaagcttt gggtatttta
      541 gtaggaaatg cgctggattt acctatactt ttaacatatt atttcggaag attgtgcaac
      601 cttattagct acgctatgct tgcttttata gctatcaagt tgtctggttc ttttaaacaa
      661 gtgatagctg ttgttacttt actacctatg aacatttatt tagcagcatc ttttaatcaa
      721 gacggctttg ctatcggttt agttttagta acaattggat tgtttattaa cttgctctca
      781 tcaaaagata aatctaacta taataccaaa ttcttccttt atttagttct atgtgggtta
      841 ctagttcttt caaaattcac atacttttta ttagtatgcc ttccattatt tattcctaat
      901 gaaaaattcg gaaaaaatac caagttagtc atcttgaaaa aattgggagg actattactc
      961 atttttcttt ttgctgcaat gtggtttaga ctttatggac aggttaaaac cccatatgtc
     1021 gcggattttc taaaagaagt aaacgttagc cagcaagtta aaaatatgct agaatcccct
     1081 atagtctata gcagtattat tattagacat atggtaatta atctgattaa tatgaataat
     1141 atttttcagt ttggcgcatt aagctatggt ataacgaacc ttttcccgct ttatgtgtgt
     1201 ttcttctttt ttgtttatat tagtaatgct agtaaaataa ctattaatat tgtagaaaaa
     1261 atgggtataa tctttgttat ttcagcgatt ataggtgcaa ctgtattagc tatgtacctg
     1321 acttggacac cagtagggtc ctcaactgtc ttaggtgttc aaagtcgtta tctgatagga
     1381 attatcccat tagtgttgct tctttttagt agtcaacagc aaaagttcaa acaaatagag
     1441 gatatccttt ctgacaaact ggctattcat gtttcgcttt tgtttattct cgcaatgtta
     1501 atgagtacta tttttagata ttatcattaa actcttaatt agaggcttta aaaaacttag
     1561 cttgaataag tattttaaag ccttttatgc tataattaaa ttgagaaatt attgaggtgg
     1621 cctatgaagt acgataactt gttagatcga tttataaaat atgtcaaagt gaatacaaga
     1681 agcgatccag acagtgagac tactcctagt acggagagtc aagaagcatt tgccttaacg
     1741 attttaaagc ctgaaatgga ggcaattggt ttgcaagatg ttcattataa tccagttaat
     1801 ggctatctta ttggaactct gcctgccaat aatccaacct tgacgcgtaa aattggtttt
     1861 atagcacata tggatacggc tgatttcaat gctgaaaatg ttaatccgca gattattgac
     1921 aattatcaag gaggggacat tacacttggc agttctaatt ataagttgga tccaaaagca
     1981 tttccaaatc ttaataatta tatcggtcaa acattgatta ccactgatgg gactacactt
     2041 ttaggggcag atgataaatc tggtattgct gaaatcatga cagcaataga attcttaaca
     2101 tcacaaccac aaatagagca ctgtgacatt aaagtggctt ttggccctga tgaagagatt
     2161 ggggtcggag ctgataagtt tgaggtggct gattttgagg tggattttgc ttatactatg
     2221 gatggcggtc ctttaggcga attgcaatat gaaactttca gcgctgcagc tctagaagtg
     2281 acttttttag gcagaaatgt tcatcctggt acggctaagg atcaaatgat taatgccctt
     2341 gagttagcaa tagattttca tgagaagcta cctgctaaag agcgacctga atacacagat
     2401 ggttatcaag gcttctatca cttaaccgga ctaactggaa cagttgaaga ggcacgcgca
     2461 tcttacatta ttcgtgattt tgaagaagca tcatttgaag ctagaaaagt gaaagttgaa
     2521 aatatagctc aatcgatgaa tgctcagcta ggaacaaaac gtgtcttggt agagcttaat
     2581 gaccaatact acaatatgaa aaaagttatc gaaaaagata tgactgctat tgagttagct
     2641 aaagaagtaa tggaagagct tgctatcaag cctgtaatcg aacccatacg tggaggaaca
     2701 gatggctcta aaatttcatt tatgggtatt cccactccta atatttttgc agggggtgag
     2761 aatatgcacg ggcgttttga gtttgttagc ttacaaacga tggagagagc tgtcgatgtc
     2821 attattggac ttgtttgcaa agcctaatta tcatgtaatt gatatttagt ggaaggggct
     2881 tataaaaatg attaaactat ttggtaaaat aaggtatcac tggcagccag agttgtcttg
     2941 gtctattatt tattggtcta ttgcgtttgc acctattttt gtaggtttat ctttgttgta
     3001 tgagcgcact gaaataccta gtcgggtttt tattctattt gctatttttg ctgtcctagt
     3061 tggcattgga ttacatcgtt atttcattat tgaaaataat ggtattttaa gaatcgtatc
     3121 ttttaaattg tttggtccac gtaagctact tatttctact attactaaga ttgaggtgac
     3181 caaatcaaca ctttgtctgc actttgaaga taaaagttat ctcttttata tgcgcaaatg
     3241 gcctaaaaaa tattttcttg atgccttagc ggttaatcca tacttccaag gagaagttat
     3301 attaagtgat aactttatta aattagacta ttttgaagtt tatcagcatg ataaaaaagc
     3361 ccttactcga gggtaagagc tttagttggg caagatttga cagctaaaat agcgtcctta
     3421 tctgaaggac aaattgactg acttgtttca gatgagcttg aaaatgtgac gataccattg
     3481 tcatgataat caaaaagtga tgaataggtt tggcatagac cacaagcgat gcatttttct
     3541 ggaatgatag atactttcat aactattatt ctaatatgat tttgttaaat taacaagggg
     3601 ggacgatcat ggctaaagaa ccatgggaag aaaaaattgt tgatgatact atagggacac
     3661 gaacacgtaa atcaagaaat gctttcatta gcacgccttg gttgactgct ttattaagtg
     3721 tattctttgt catcattgtt gctatacttt ttattttctt ttatacatca aatagcggta
     3781 gtaatagaca agctgaaaca aatggttttt atggagcatc cactcataaa aaaacaagga
     3841 aagcttctaa cgctaaaaaa gcatcaagta gttcaacaac tacagacaca acaccttcta
     3901 gcgaagaaac acttgcttct agtgaaggaa ctggcgaaac ccttactgta ttggcaggtg
     3961 agggggcagc ttctattgca gcccgtgcag gtatttctgt ggagcagtta caagcactta
     4021 atccagagca catgactcaa ggatattggt atgccaatcc aggagatcaa gtcactatta
     4081 aataattgaa gaggaaaaaa tgaaagcaat taaaattgcg attgatgggc cagcttcaag
     4141 tggaaaaagt acagtagcca agattattgc aaaaaatctt ggctatactt atctagatac
     4201 tggtgctatg tatcgctcag caacttatat cgcactgaca catggctata cgggtaaaga
     4261 agtagccctt attttagagg aacttgagaa aaatcctatt tcctttaaaa aagcaaaaga
     4321 tggctcccaa ttagtttttc ttggggatga ggacgtgacc ttagccatta ggcaaaatga
     4381 tgtgactaac aatgtttctt gggtctcagc tttgccagaa attagagaag agctggttca
     4441 tcaacaaaga cgcattgcac aagctggtgg cattatcatg gatggtcgtg acattggaac
     4501 ggttgttctc ccagatgcgg aactaaaaat ctttttagtg gcttctgtcg aagagcgggc
     4561 agagcgccgc tataaagaaa acctagaaaa aggaattgaa tcagattttg agacgctaaa
     4621 agaagagatt gcagctcgtg attacaagga tagtcatcgt aaggtttcac ctctaaaagc
     4681 agctgaagat gcccttattt ttgataccac aggtgtttct attgatggcg tggtgcaatt
     4741 tatccaagaa aaagcagaaa aaatagttga catgtcctag agcctatgtt agaatattaa
     4801 caatgagaaa agtagaagtg agagcttctc gccttgcgac ttaggttgtc tggccctaac
     4861 atgtcaaatt cctatggaat attatgtgtg cgggcttgat ttatcaagtc cgctttcgtt
     4921 tttctctaaa aaaataaaga ggtgaagatc atagctaaaa aggatctatt cattaatgat
     4981 gaaattcgcg ttcgcgaagt tcgtctcgtt ggtcttgaag gtgaacaatt aggtattaaa
     5041 ccattgtctg aagcgcaatc attggctgat gcttcaaatg ttgatttggt tttaatccag
     5101 ccacaagctg ttcctcctgt tgccaaactt atggactatg gaaagttcaa atttgagtat
     5161 caaaagaaac agaaagaaca acgtaaaaaa caaagcgttg tgactgtgaa agaagttcgt
     5221 ctcagtccag ttatcgataa aggtgacttt gaaacaaaac ttcgtaacgg tcgtaaattc
     5281 cttgaaaaag gaaataaagt taaggtttct attcgtttca aaggacgtat gattactcat
     5341 aaagagattg gtgccaaggt actagctgac tttgctgaag cgactcaaga tattgctatc
     5401 attgagcaac gagcaaaaat ggatggacgc caaatgttta tgcaacttgc accaatttca
     5461 gacaagaagt aattgtcaca gtttcattat atctttaaga ggagaatact aaaatgccaa
     5521 aacaaaaaac acaccgcgca tcagctaaac gttttaaacg tacaggttca ggcggtttga
     5581 aacgcttccg cgcctttaca tcacaccgtt tccacggaaa aactaaaaaa caacgtcgtc
     5641 atcttcgtaa agctggtttg gttagctcag gagatttcaa acgtatcaaa gcaatggtta
     5701 ctggtcttta attttaaagg cagtagacat ttacgagtat tataagaatt atttgaagga
     5761 gaactattaa tggcacgtgt taaaggtggc gttgtttcac gcaaacgtcg taaacgtatt
     5821 ttaaaattag ctaaaggtta ctatggagca aaacacatct tgttccgtac tgcaaaagag
     5881 caagtgatga actcttacta ctatgcatac cgtgatcgcc gtcagaaaaa acgtgatttc
     5941 cgtaaactat ggatcactcg tatcaatgcg gctgctcgta tgaacggttt gtcatactca
     6001 caattgatgc acggtttgaa acttgctgaa atcgaagtaa accgtaaaat gcttgctgat
     6061 ttagcagtag ctgatgcagc agctttcaca gctcttgctg atgcagccaa agcaaaactt
     6121 ggcaaataag aaacgctata cctaaaaaat aactttctat tacctataga aagttataaa
     6181 gaaacaaaaa tgaaggagac gatggacgtc ttctttttat tatactcaat ataataaaaa
     6241 gcagtttccc atgttttatt accagtaatg tgggatattt agatggtagc aaggagtttt
     6301 atagctgatt tgttttcttt aggtctaatt agcatatttt gattactgat aaacttgaat
     6361 atcgccaata aaaaagaagc aaaattatta ttttgcttct agtcagatca ttaaattgat
     6421 tattctttat ttttggggtt atcctctttt agttcagaag ttgccgcgtc agcttctacg
     6481 ggatttagtt ctaagtaaga tggtgcttta aaaagtttct gagttgattt atgaccattt
     6541 ttactgtata aacttgttga ctctgatccg agttttgctg aaatatcttt cagttgtttt
     6601 aactgcttag tgtagataaa ctggttagga tcaatagctt ttagaccatt ttgagtatca
     6661 aagcgcagga gatcacccgt ttgaatagcg tcgctagctg ctagttgttg agcaacagca
     6721 gagcgaattt ccttagtttt ggctatagtc atttcatcgg gattagtgat ttctaaacct
     6781 gtttgcgtgt tgtacagacg tccactatag ttagtgtatt caggagtcat ataagtccca
     6841 gatgttcgtt gtgccacaat ctggctattt tgaggtgata ataagtcttg tcctaattga
     6901 acaaactgac tagtgtcaat accaagtatg tggagtaaag taggaagagc atcgatttca
     6961 ccgccaaagg tttctttgat actaccattc gtataacctg gaatatggat catatacggg
     7021 actcgttgta gcatagcatt atcatattca gaccaagttt cagaatcttt accaagaagt
     7081 ggagcaagac tagaattacg agaatttgaa ataccataat gatcaccata taaaacaaaa
     7141 atagaattct cgtacaaacc agtggctttc aagtaatcaa aaaaagattt aagggcagcg
     7201 tctaaataat tggcagtagc aaagtaacca ttgatcgttt catcgtctgt tttggctaaa
     7261 ggaaaacctt cttcactact ttcgcctttt agactagtat aaggatagtg attactcaca
     7321 gtgataaact tggtataaaa aggttgttgc atctgttcaa gatattttat ggaatcctta
     7381 aacatgtact tatcatttaa cccatattga aaagagttct tactattttg tttagagaag
     7441 tagctagaat caaaaaaata attatagccc cattgtttat aagcattatt gcgattccag
     7501 aaagttccaa cgttaccatg aaagacagcg ctggtatagc cacctttttg ggttaaaata
     7561 cttggagtag caaattgtgt attttcacca ccgtagttca ccataaaaga accactattt
     7621 aaaccaaata aggaattctc catcatggtt tcagcatcag aagttttacc tgctttaacc
     7681 tgatgaaaaa agttagggaa tgctaaggta gcatttgagt gataaagcga gttgataaaa
     7741 ggtgttacct catattcttt atctccttct tttagtttat aatctattaa gaattgttga
     7801 aagctttcta aatgaagaac aataatattt ttgccttttc caattccaaa atactgagga
     7861 tcaggtgctg cataatgtcc tttgacataa gttttaacat caattaattc ttctgcagta
     7921 gctccatttc gttctttttg agcttgatag gtttgattgc cgctatagag ggtaaacgct
     7981 ggtagtccta aagctctcac aatataagta tttgaaaagc cacgtgttaa tagttccgga
     8041 cgatcaattt ctgctaaaaa aagattaata gaaagcaata gactagataa agcggtgatg
     8101 gcaaatgctg cgcgcttgtt aaaaggacgt tggtcatttt tgattttttt agtgatagat
     8161 aaactaatta gaataataaa atcaagaata tagataatat cccagatgcg taaaaggttt
     8221 aaagcagagt cccctaatcc agcggagact ttactactag ctagcatggc actcactgta
     8281 ataaagtctg aaaattctcg gtaatatata gaatttgata tcaagagaat gttaaggata
     8341 atataaacca cccaagaaca gatataaaag gctcgggtat tcttaacgta aagagcaacc
     8401 cccaaaagta aaaaagctag tgggattgga ttgataatag ttagaaagac ttggtatata
     8461 tttcccaaat ctagtgaaaa gtctgtatga tatgcccaca gggtctttat ccagtaacaa
     8521 aagagtagag taattataaa acccaatctt gtgttgataa aacctgtgat aagtgtttta
     8581 aatttcttca cagtagcaac ttccttatcg ttttttccta aagatgtcat ctccaaataa
     8641 aatctcagat taaattatac caaaaatgtg aagctaatgc ttgttgtaag ttcaaattta
     8701 gtaggatttt ttatcagatt ttgttataat aaaaactatg aataaactct atattgattc
     8761 ttttgtcgaa aagaagctga cagcaggggt acaattatta gatgaaaaag atttttctaa
     8821 tataaaggaa aaaaatcagt tggttcaact ggtgaccaag tccaatcgtc ccattggaac
     8881 agcatatatc tctaagcaaa ataaaggaat tggttggtat ctaggaccag aaaaaatcga
     8941 cttgtctatc tcttattttg ttagtctatt ttcagttgct aaggccaaaa gacaagattt
     9001 tgctcaatcg gacgagacca atgcttatcg cctttttaat caagaaggag acggttttgg
     9061 tggagtaaca attgatcttt ataaagattt tgcagtcttt tcatggtaca atgcctttgt
     9121 ctatgacaaa aaagaaatga ttatggaggc ttttcaacag gtttttcctg aagtcaaagg
     9181 agcttatgaa aagtgtcgct ttaaaggtcc agatactgaa actgctcatc tgtatggtga
     9241 gctggcacaa gaaacctttt cgattttaga aaatggcata gcctatcaag tcttcttgaa
     9301 tgagggctta atgacaggtg tttttctaga ccagcatgat gttagaagag cactagtaga
     9361 tggtttagct atgggcaagt cccttcttaa cctattttcc tatacggctg ccttttctgt
     9421 agcagctgct atgggtggtg ctatcgagac cacttctgtg gacttggcta aacgatcgag
     9481 agaattatca ctagctcatt ttgagcataa ccagttaaac ttagcctcac atcattttgt
     9541 ggtgatggat gtttttgaat acttcaaata tgccaaacgg aaaaaattaa tctttgatgt
     9601 gattgtgatt gacccaccaa gctttgctag aaataaaaaa caaactttct ctgtgagcag
     9661 ggactaccac aaattaatca cagaggcctt ggacatattg agtcctaagg gaactattat
     9721 agcttcaaca aatgctgcta atatgactgt tagccagttc aaaaagcaaa ttatcaaagg
     9781 atttggaagt cgtcgtcctg agtctatgac tctccagcag cttccgagtg actttactat
     9841 caataaagca gatgaaagaa gtaactattt aaaggtattt actataaagg tacgagaatg
     9901 agaattgtag caccagtcat gccaagacat tttgacgagg ctcaagccat tgatatttct
     9961 aaatatgaag atgttaattt aattgaatgg cgagcagact ttcttcctaa ggatgagatt
    10021 gtcgcagtag caccagctat ttttgaaaaa tttgccggaa aagaaattat ctttaccctt
    10081 cggaccgttc aagaaggggg gaatattacc ctttcaagtc aggagtatgt tgatattatc
    10141 aaagaaatca atgctattta taatccagac tatattgact ttgagtattt tacgcacaag
    10201 tcagtatttc aagaaatgct tgattttcca aatcttattt tgtcttatca caactttgaa
    10261 gagactcctg aaaatttaat ggaagctttt tcagaaatga ccaagttggc accgcgtgtg
    10321 gttaaaattg ctgtgatgcc ccagagtgaa caagatgttc tagatttgat gaactatacc
    10381 agaggcttta agacgctcaa tcctgagcaa gaatttgcaa ctatatctat ggggaaatta
    10441 ggaagattgt ctcgttttgc gggagatgtc attggctctt cctggacata cgtttcatta
    10501 gatcatgtta gcggtccagg tcaagtgact ctcaatgata tgaaacgtat tattgaggtc
    10561 ttagaaatgg atatctctaa ctagtgaatg gtctaaaaat attatttcta caatagttaa
    10621 gaaatgatgt ttttagatta atgtttttaa aataagtgga accaaaaagg agaaaaattg
    10681 cgttatttaa cagcaggaga atctcatggg ccatccttaa cagctattat tgaaggtata
    10741 ccagcaggat taactcttca tccagcggat attgatcacg aattacagcg acgtcaagga
    10801 ggttatggcc gtggtgccag aatgtctatt gagactgatc gggttcaaat atcctcagga
    10861 gttcgtcatg gcaaaacaac aggggccccc attaccttaa cggtaattaa taaggaccac
    10921 caaaaatggc tagatgtcat ggctgtagga gacattgaag agactctcaa gttaaagcgt
    10981 cgtgttaagc atcctagacc aggacatgcg gatttggtag gaggtattaa atatcatttt
    11041 aacgatttaa gagatgcttt agagcgttcc tcggctagag aaacaacgat gagagtggct
    11101 gtaggcgctg ttgctaaacg tatcttagct gaacttggaa ttgatatgtt acatcatatc
    11161 ttaatatttg gtggtataac gatcacaata ccttctaagc tctcttttag agagttgcaa
    11221 gaaagggctc tccattcaga gttatctatt gttaatccaa agcaagaaga agaaattaaa
    11281 acgtatattg ataagataaa aaaagaaggg gatactattg gtggtattat cgaaacgata
    11341 gttcaagggg tgccagcagg tcttggatct tatgtccaat gggataaaaa attagatgcc
    11401 aagctggctc aagcagttct ttccattaat gcttttaaag gggtggaatt tggagttggg
    11461 tttgatatgg gattccaaaa gggctctcag gtaatggatg aaatcacctg gacacctacc
    11521 caaggctatg gtcgtcaaac aaaccactta ggtggctttg aaggtggcat gaccacagga
    11581 caacctcttg ttgttaaagg ggttatgaag cccattccta ctttgtataa accactcatg
    11641 tcggtagata ttgatagtca tgaaccttat aaagcaacgg tggaacgctc tgatccgacg
    11701 gccttaccag ctgcaggggt tatcatggaa aatgtggtgg cgacggtgct tgccaaagag
    11761 attttagaga ctttttcttc tactaccatg tctgaattgc aaaaagcttt ttcggactat
    11821 cgtgcctacg tcaagcaatt ttagatagcg agatactggc ttttatggta tcatacaggt
    11881 attaatgaac aaaaggagac tgtcatgtca caagaaattt atgactatgc taatcaactt
    11941 gaaagagcag ttcgtgctct gccagaatac caaaaagtgt tagaagtaaa agaggccatt
    12001 caagcagacg ctagtgctag cgaactgttt gatgagtttg tcgctatgca agaaaaaatc
    12061 caagggatga tgcaatcagg ccaaatgcca acggctgaag aacaaacaag cattcaggaa
    12121 cttagccaaa agattgaagc taatgaccag ctaaaagctt attttgaagc gcagcaggcc
    12181 ttatctgttt acatgagtga tattgagcgt attgtatttg ctccgttgaa agatttagtc
    12241 aagtaagcca attaagatag gaaaaaaaac agattgctgg cagctcgtca ggatctgttt
    12301 tttagtgttt attttctttg tatcagaaag ttgagcctct ttcttatttg tgatatagtc
    12361 aaataaattg accaaaatag caggccagta gtggctttaa tgaaggcaag ttgtctgcta
    12421 actggctatg ctaaaacatc agtattagaa agtaaaaggt tataaaaatg gttattcctt
    12481 atgattatat tgttattggt ggagggagtg caggtattgc ttctgcgaac agggcagcca
    12541 tgcatggggc caaagtattg ttagctgaag gtaaagagat tgggggaacc tgtgttaacc
    12601 taggctgcgt tcctaaaaaa gtcatgtggt atggcgctca agtagcagat attttaggga
    12661 cttacgctaa ggattatgga tttgacttta aagacaaagc atttgatttt aaacaattga
    12721 aagcaaatcg tcaagcttat attgatcgga ttcatgcttc ttatgagcga ggctttgagc
    12781 agaatggtgt tgaccgtatt tatgattatg ctgttttcaa agatgctcat acggtagaaa
    12841 ttgcagggca gctttatacc gcaccgcata ttttgattgc cacaggagga catcctgttt
    12901 ttccagatat tgagggggca caatacggta tcagctcgga cggctttttt gccttagatg
    12961 aggtaccaaa acgtacggct gtggttgggg caggctatat tgctgtggaa cttgccggtg
    13021 ttttgcatgc tttggggtcg aagacggatt tgtttatccg tcacgatcga cctttaagaa
    13081 gttttgacaa agccattgtg gatgttttag ttgaggaaat ggcagttggt ggtccttgct
    13141 tacaccctca ttcagaagtg gcaaaggttg tcaaaaatac tgatgagtcc ttgacccttt
    13201 acctcaaaga tggccaagaa gttgaggttg accagctcat ttgggctatc ggtcgcaagc
    13261 ctaatctaga aggttttggt cttgacaaaa ctggagtgac gttaaatgat aaaggttata
    13321 ttgagacaga tgcctatgaa aacacgtctg tcaaaggtat ttatgccgtg ggagatgtta
    13381 atgggaaact ggctttaact ccagttgctg tggcagctgg acgtcgccta tcagagcgtc
    13441 ttttcaatgg caaaacagac gagaaattgg actaccaaaa cgttgctact gtgattttta
    13501 gtcaccctgt tattggctct gttggcttgt cagaagaagc agcagtcaaa cagtatgggc
    13561 aagaagcagt taaaacatat caatcacgtt ttacgtctat gtttactgct atcactaacc
    13621 atcgccaacc ttgtctgatg aagttggtaa cagtcggaga taccgaaaaa atagttggtc
    13681 ttcacggaat cggctatggg gttgatgaaa tgattcaggg ctttgcagta gccatcaaaa
    13741 tgggagcaac caaggcggat tttgataaca ccgttgctat tcacccaact ggctcagaag
    13801 aatttgtcac catgcgctaa aaaatgtagc ctaaggcaat aaaaaatgat gttaacagtt
    13861 tttgaggaaa gtcttctaaa ctgctagcat cgttttttgt taggtgatta ggggaatatg
    13921 tttttaaaga tatttgcgtt gctcagacaa tattgcctta cctcggagat aaaataaagt
    13981 gaccctgtaa caacaaagag ttcatcagat gttacggaac cttgtaacca gtctctgtaa
    14041 tcttttacct gtgggtattt atcaggataa tcctctaaaa gatttgcttc agggaaatca
    14101 aaagtcgtga cagatacttc aaaagtatct agttgagcca gcaagtcggc taaaggctta
    14161 cgtttgagac ctgcaaagag aatatgaata ggacgtttgg gaaattcttc ttgcagtaga
    14221 gactttaatt tagcaatgga atctggattg tgagcgccgt ctaatagaag attaggttga
    14281 ataaattcgg accggccagg ccaagttgtt gcctcaattc ctttttgaat cgtttttgga
    14341 gatattttag gaaaggattt tctaagtaat tgagctgtca taatggctaa acaggcattc
    14401 gctttttgat gttgacctaa tagtttgaga cggagtttgg ttaaattcaa gttatcgtgt
    14461 tgaaaggaaa acgtcttttc tgaaggattg agcaaaaaat cttttcctaa ttgatataag
    14521 cgtgaaccgg ctttttgggt aacttgttga aagacttgac tagcctcctg ctcaagttga
    14581 ccgataataa cgggttcttt agctttgata acttctgctt tttggtgagc aatttctgct
    14641 aggctataac ctaaacgttc ttggtgatca aaactaatag aagggcatac gacggccaga
    14701 gcatgaaaaa cattggttgc gtcggttttc ccaccaatcc ctgcctcaat aatggcaata
    14761 tcaacaggtt taagattggc aaagtagcaa aacattatga gagtcactaa ctcaaactcg
    14821 gtaggtctat cccaatttgt ttcaagggac attttagtga gaatgggtct aatcacgctc
    14881 acacattgcg ccaattctag gtctgaaatg ggctggccat taaggcaaat ccgatcgtga
    14941 aaagagataa taaaaggaga tgtaaaggtt ccgacctgat aaccagaagt tgacaggata
    15001 tgctgtaagt aggctgtcac agagcccttg ccgttagttc caacaacgtg aatagcaggg
    15061 aatttgtctt gtggccggcc taatgcctca agtaaccaag ccattctggc caaatcggtc
    15121 ttgcgaccat tagccttaaa ggtatgaatc caggaaatgc tatcataggt agtcattact
    15181 atttcttgtc cttctaacaa tgcttttaag agttcgtagg gagaccagta ttagcatcct
    15241 cagctccagt tgcattagga agttgcgtcc cttcagtggc tgatggtgtc tcaggagctg
    15301 taggagttgt ctcgttgtga gaaggtgtgg tagaagatga cggaagagtt gtcttattat
    15361 catctgtggt ttctgaagta cctgtatggt tttgattacc ctgagaagac tctttttcaa
    15421 taatcttgac aatggtatta ctcgattctt tgggtgtatc attagaggtc ttatctggta
    15481 caggctgcag tgctcttgta atggtaatgg ttgccacaat gatactcaaa atactaccaa
    15541 taagtgcaat ggatttttgg aaagctgtaa aacctgtttt aatatgctcg gtagggacac
    15601 ctcctgattt acgaggtttt tgttgacggg aataacgtga tgacatattt ttctccttta
    15661 aaatcatcgt aatgccaaga ttaaggagga ggaaatagaa gtcctagctc ctctttaaca
    15721 cttcatctat cagtataatc tagaaaaaaa gtgaagtcaa cggtttacct tatgtctagg
    15781 acaaggaagt cctttgggct tattgtaata cgaatattct tgatttcatt ttagctattt
    15841 tgtgatagaa taaagtattg agtaaaaatg aaggtgacac atgatttatt ttgataatgc
    15901 agccacaacc ataccttatg gagaggctct taaaacttac caagaagtag caacaaaaat
    15961 atatggcaat ccctcaagtc tgcaccaatt agggacaaat gcgtctcgca ttttagaagc
    16021 ttcccgtaaa cagattgctg gtttgttggg tgttaagtca gaagaaatct tttttacgtc
    16081 tggtgggact gaaagtgcta attgggctat taagggaatt gcttttgaaa aaactgcttt
    16141 tggcaaacat attattatct cagccattga acaccctgcc gtgagtgaaa gtgtcaaatg
    16201 gcttctcaca caaggattcg aagtttctta tgctccagtg acaacacagg gagttgttga
    16261 tgtgaatgct ttagctgagc tgattagacc agacaccatc ttaatctcga ttatggctgt
    16321 taataatgaa atgggagcta tccaaccgat tagagccatt tcaaacctat tggctaacca
    16381 accaacgatc acctttcacg ttgatgctgt tcaagccatt ggtaaaatac cactctgtga
    16441 ttatatgact aatcgtgtgg atttggcttc tttttcaggg cacaaatttc atagtgttcg
    16501 tggtgttggc ttcctttata aaaaagcagg caagcgactc aatcctctct tgtcaggcgg
    16561 cggccaagag caggagttac gttcaaccac tgaaaatgtt gcaggaattg ctagcatggc
    16621 caaagcatta agaatagtca ctgaaaaaca agtgagcgtc ttacctaaac taacagcgat
    16681 gcgagatgtg atttacaaag ctttgtccgc ttacccagat gtgacagtat tttcagctca
    16741 agaaggcttt gcgcccaata ttttgacctt tgggattaga ggggttcgag gagaagttat
    16801 tgtccacgcc tttgaaaaat atgagattta tatttcgacc acaagtgcat gttcgtccaa
    16861 agcaggtaag ccagcaggaa gcctagtggc tatggggatt cctgtaaaaa ctgcccagac
    16921 agccgttcgt attagtctag acgatgacaa cgatatggga caagtagagc agtttttgac
    16981 catattcaaa cagatttatg ataaaacaca gaaagttagg taagattagg taagatggac
    17041 tattcagaaa ttatggttcg ccatggtgaa ctgtcaacta aagggaagaa tcgcatgcga
    17101 ttcattaaca aacttaaaaa caatattcaa gacgtactgg ctcctttccc agccattgct
    17161 gtccgttcag atcgtgatag gacccatgtg tctctaaatg gcacagatta tcagcctatt
    17221 gtagaagctt taaagctggt gtttggtgtt caagctctat ctcctgttta taaacttgaa
    17281 aaaagtgtcc ctcttttggt aacagctgtt caagatatca tgacttctct ttatcgtgat
    17341 ggactgacgt ttaagattgc cactaagcgt agtgatcacg cgtttgaatt ggatagtcgt
    17401 gagcttaaca gtcttcttgg tggagctgtt tttgaggttt taccaaatat ccaagcccag
    17461 atgaaacatc ccgatgtgac tctcaaagtc gaaattcgtg atgaagcagc ttacatttct
    17521 tatgaagaga ttaagggagc aggcgggtta ccagtaggaa cgtcagggaa agggatgctg
    17581 atgttatcgg gcggtattga ttcaccagta gctgggtatt tagcccttaa acgtggcctc
    17641 gatattgaag ttgttcattt tgctagccct ccgtacacca gtccaggtgc cttggctaaa
    17701 gcccaagacc ttactcgtcg gttaactcgt tttggtggaa atatccaatt tatcgaggtt
    17761 ccttttacag aaattcaaga agaaattaaa aataaggcac cagaggctta ccttatgaca
    17821 ttaacccgcc gctttatgat gcgcatcaca gatgccattc gtgagcaacg taagggtctt
    17881 gttattgtta acggtgagag cctaggtcag gttgctagtc aaacccttga aagcatgcag
    17941 gccattaatg cggtaacatc aaccccaatt attagaccag tcgtgacaat ggataaactt
    18001 gaaattatcg agatggctca ggcgattgat acttttgaca tttctattca accgttcgaa
    18061 gattgctgta ctatttttgc accagaccgt cctaaaacca accctaaact aggtaatgct
    18121 gaaaaatatg aagaacgctt tgatattgat ggtcttgtcc agcgtgctgt gtcaggaatt
    18181 gttgtcacag aaatcacacc tgaaatcgtc aatgatgagg ttgaaaatct cattgatgct
    18241 ttactttaaa agaaaagatc aagtgtaaat cttttagtag tcagtaatga tactattgaa
    18301 aagcctctat aagggctttt ttgctgcaat gaaggaggaa aattttgagg caagatgtta
    18361 taatagagaa aaaggagggt gtgtcttgat taaaactatg caatacaaaa aaacgatggc
    18421 aacagttgtt gctcttatcg tcgcactttt gctatttggc ttgatttatg atttacttgg
    18481 ggttcaaaaa aataagctag cagctcaaaa atctgctcag ccaaaggtca aaacagcgcg
    18541 tgttgtagct aatggcgaca ttttaattca tgatattctc tacatgagtg ctagaaaagc
    18601 tgacgatacc tatgatttca ctccttattt tgaatatgtt aaggactgga ttagcggtgc
    18661 tgacttagct attggagatt atgaagggac cattagccca gattatccct tagcaggcta
    18721 tcccttattc aatgctccag aagagattgc aggtgctctg aaaaatactg gctatgatgt
    18781 agtcgattta gcccataatc atatcttaga ttcccaatta gacggtgccc ttaacactaa
    18841 aaaggttttt catcaattag gtatagacag tattggcatc tatgacaagg atcgttcaaa
    18901 agaatccttc ttaattaaaa atgtcaatgg tatcaaaatt gcaattttag gttattctta
    18961 tggttataac ggcatggagg ccacacttag ccaagaagac tatgagaaac acatgtctga
    19021 tttagatgaa gctaagataa aaaaagaact tcagctagct gaaaaaaagg ctgacgtgac
    19081 cattgtcatg ccacaaatgg gaacagaata tgccttagaa ccgacagcag agcaaaaaga
    19141 actttaccac aaaatgattg attggggagc tgacgtcgtc ctaggaggcc atccgcatgt
    19201 tattgaacct tcagagacag ttataaaagg taggcaaaag aaattcatta tttactctat
    19261 gggaaatttt atttcaaatc agcggcttga aaccgtagat gatatctgga ctgagcgtgg
    19321 cctattgatg gaccttactt ttgagaaaaa agataacaaa acaaaaatta aaacagttga
    19381 ggcccatcca accatggttt tagccaaagg taaaggcatt gtgggtaaag aaggttttga
    19441 actatacaat tatcgaacaa tggttttaga agattttatc aaaggtggaa aataccacga
    19501 caagattgat gaggaaacca aagcaaaagt agcacttgct tatcaggaaa ttaatgattt
    19561 agttaacctg aaatggtaat gtttggtggt ttagcatcta acgataaaaa atagagatta
    19621 aacttaattt ttccttgata aaaagcagtt atggtgctaa aatagtaacg ttgactaaat
    19681 gcacatcctg tgcaaccgcg cgaaaatcgt tgtcaagtag accaagtctc acgattccag
    19741 gcgagtcttc acagagggaa acctcaaaca aaaattttat aggaggtgca tcatgagcac
    19801 atacgcaatc atcaaaactg gtggaaaaca agttaaagtt gaagtaggtc aagcaatcta
    19861 cgttgagaaa attgacgctg aagctggcgc agaagtcact tttaacgaag ttgttcttgt
    19921 aggtggtgac aaaactgtag ttggtactcc agttgttgaa ggagctactg tcgttggaac
    19981 tgttgaaaaa caaggaaaac aaaagaaagt tgtaacattc aaatacaaac ctaaaaaagg
    20041 tagccaccgt aaacaaggtc atcgtcaacc ttacactaaa gttgtcatca acgcaatcaa
    20101 cgcttaattt actagcttat gattaaagca atttttactc gccaaaaaaa tggtcaactg
    20161 agcagtgtta cactgacagg tcatgctggt agtggtaaac atggctttga tattgtttgt
    20221 gcctctgtta gtactctagc cattaacttt gttaattctc ttgaggtgtt agcagattgc
    20281 caagcattag tagatcttaa tgatgttgaa ggtgggtata tggctattac aataccacca
    20341 catgacaaca aggaggaagt tcaattatta tttgaatctt ttcttctagg aatgactagt
    20401 ttggcgaagg attcttcgaa atttgtcaac actcaggtca tctaaattta atttaagaga
    20461 ggaaacaaca ttatgttaaa aatgaatctt gctaacttgc aacttttcgc ccacaaaaaa
    20521 ggtggaggtt ctacatcaaa cggacgtgac tcacaagcta aacgccttgg tgctaaagct
    20581 gctgacggtc aaactgtttc aggtggatca atcctttacc gtcaacgtgg aactcatatc
    20641 tacccaggtg taaacgtagg ccgtggtgga gatgacacac tttttgctaa agttgaaggt
    20701 gttgtacgtt tcgaacgtaa aggacgtgat aaaaaacaag tttctgttta cccagtagct
    20761 aaataattgt ttaacatcgc attatataag gctttccagg tgtctggaaa gccgattttt
    20821 ttattttggt actcatgttg ctatccatat tttaaaaatc aatgtaggaa gagagcttgt
    20881 cagcagtttt atcttttgag gatttagtaa catgagcgta gatgttcatg gtagtttgga
    20941 tagtttcatg accaagtgta ttggattttc attgtttgtt tctatcctac taaagattgt
    21001 agttgcttat ttagagcaat agttctaatt gtaaaaagtc agcataataa aacaatgtca
    21061 taagatgttg ttataacggg ctttatggta taattaagga tactcatttt aggaaggaaa
    21121 gcaatgaata ttcaacaatt acgctatgtg gtagccatcg ctaataatgg aacttttcga
    21181 gaagctgcct ctaaattgtt tgtcagtcag cctagcttat cagtttctat caaagattta
    21241 gaggcggaat tagggtttca aatttttaat cggactactt caggaacagt cttgacaagt
    21301 caaggactag ttttttatga gaaagcttta gaagtagtca aatcttttga ttcttttgaa
    21361 aaaacctttt ctcaagctga tctggatcaa aatgaatttt ctattgctag ccaacattat
    21421 gactttttgc cacctcttat tacagctttt tcgcaacaat acgatggtca tcgtgtcttt
    21481 cgtatctttg aatcaacaac tattcaaatt ttagatgagg ttgctcaagg aaacagtgaa
    21541 attggtatta tttacttgaa tgtagacaat caaaaaggtc tctttcagcg gatggataag
    21601 ctgggcttgg aatatgtttc tctaattcct ttcactactc atatttatct ttcaaaaacg
    21661 catccattgg ctaatcgcga agcgctttat ttgagcgata ttcaaggatt acctgcggta
    21721 aggtttaccc aagaaaggga cgagtatttg tattattctg aaaattttgt ggatactagt
    21781 gaatgccctc gtatttataa tgtgtcagat agggcaacct tgaacggtat tttagagaga
    21841 accaatgcct ttgcgacagg atcaggtttt ctcgatcatc ggagtgttaa tgggattaaa
    21901 gtgatacctc tagctgatca tattgacaat caaatgattt atgtcaaacg aaaagataaa
    21961 aacctttctg ttgctggggc cacttttgtg actattttaa aagactattt tgataaaaga
    22021 aggaaggcct taacatgaaa aaacgattgt ttgtgcttag cttgatcctc cttgtagctt
    22081 tggatcaact tagtaaattt tggattgttt ctcatatagc gcttggagaa gtgaaaccct
    22141 ttatcccagg tatcgtcagc ttgacttact tgcaaaacaa tggggccgcc ttttccatat
    22201 tgcaggacca gcaatggttc tttgttgtca taacggtttt agttatcggt tatgctattt
    22261 attaccttgc tactcatccc catttaaata tctggaaaca attagctctc ttgcttatta
    22321 tttctggtgg aatcgggaat tttattgatc gtttgcgttt agcttacgtg attgatatgg
    22381 ttcatttaga ctttgtggat tttgccattt ttaatgtggc agattcatac cttaccgttg
    22441 gtgtcatatt attagtgata tgtttatgga aagaagagga ttatggaaat taatgtgata
    22501 acatcggggc aacgcttgga taaggcacta gctgatttaa gtcccctgtc acgtggtcaa
    22561 gccaatgacc aaattaagca aggccttgtt ttagttaatg gtcagcaaaa aaaggctaaa
    22621 tatacggttc aagcaggaga tgtgatttgt tttgaactcc ctaaagaaga agtcttagag
    22681 taccaagctc agaatattcc cttggacatt atctatgaag atgatactct cgccattatt
    22741 aacaagccac agggaatggt agttcaccct tcggcgggac acccttcagg aacaatggtt
    22801 aatgccttga tgtatcatat caaggatttg tcctcaatca atggtgtggt tcgtccagga
    22861 attgttcatc ggattgataa ggacacctca ggtctcttaa tggtagctaa aacagatgca
    22921 gctcatcaag ccttggcaga agaattaaag gctaaaaaat ctctcagaaa atacctcgcc
    22981 attgtccatg gaaacctacc gaatgatcgc gggatgattg aagctcctat aggtcgtagc
    23041 gaaaaggacc gtaaaaaaca ggctgttaca gcaaaaggca aagaagcagt gacacgtttt
    23101 acagtgctag aacgttttgg cgattacagt ctagtggaat tacaactgga aactggtcga
    23161 acgcaccaaa ttcgtgttca tatggcctat attggtcatc ctgttgctgg ggacccttta
    23221 tatggaccac gtaagacact atcaggtcat ggccaatttc ttcatgcaaa aacattggga
    23281 ttaacgcatc ctatgacagg aaaagaaatg atatttactg ttgaagctcc cgaaattttt
    23341 caaaaggtgt taaagctgct aagaaaaaaa taaacagcga ggagtagcca ttatttttag
    23401 tcttatatct ttgtgtaaag tttttaacat tataaaaaat actaaaaagc atttacgata
    23461 agccaggaaa tatgagaagt cttttatgtt attgggatat gcaacatatc tgttagagat
    23521 ctttatttaa actcttaaag aaaagagata ttccaaatag atgctaggta ttgtcttttt
    23581 tacttgtttt tcttttcttt ttttgctata ctgattgaaa taaaatattc ctttaaaaca
    23641 gtcctgtgag gctgtcaagg agacggatta aaaacatgca ctatgatact taattgtgct
    23701 atattttgct gaatctcctt gtttccaagg agatcttttt atttgaattt ttagaggagg
    23761 tttcaacatg aaaactaagg aaattgttga tgatgtgacc atgaaacgcg ccattacccg
    23821 tattacttat gaaattattg aacgtaataa acaattagac aatgtggttt tggcaggcat
    23881 caaaacgaga ggtgtttttc tagctcgtcg cattcaagaa agactgcatc aattagaagg
    23941 gttggattta ccaattggtg agttagacat caagcctttt agagatgaca tgagagttga
    24001 ggaagacaca actctgatgt cagtagatat tacaggcaag gatgtgattt tgattgatga
    24061 tgtgctttat actggtcgta ccatccgcgc ggccatcgat aacttagtga gtttaggtcg
    24121 accagcccgt gttagtctag ctgttttggt ggatcgtggc catcgggaat taccgattcg
    24181 cgcggattac gttgggaaaa atattccaac aagcagtgta gaagaaattg ttgttgaggt
    24241 tgtcgaagtt gatggccgtg atcgtgttag cattattgac ccaacataag aaggaggttt
    24301 tactgtgaaa gatgtcattt atgatgtgga agaagtgcca aaggcaggta tgttagttgg
    24361 tttgtccttt cagcatttat ttgccatgtt tggggcgacg gttcttgttc ctattttagt
    24421 tggaattgac ccgtctgtgg ccctcctatc gagtggttta ggaacacttg cacatttatc
    24481 ggtaaccaaa tttaaaattc cagcctacat gggctcaagt tttgcttata tagcagctat
    24541 gcagttactg atgaagacaa atggtattgg tgctgtagct caaggggcta tgacaggagg
    24601 tctcgtttac ctgattgtag ctttgattgt taaagttatt ggcaatgatt ggattgataa
    24661 gattttacca ccgattgtag ttggtccgat tgttatggtc attggtctaa gtctagcttc
    24721 tacagctgtt aatgatgtca tgttaaaaaa tgggaactat aatctgactt atcttgttat
    24781 tgggttagtc accttattat cagttatttt tttcaatatt tatggtaagg gaattgttgc
    24841 tattgtaccg cttttattag ggctattagt tggttatgtt gtagcccttt tagtgggtgt
    24901 tctcaccggt caagaaattg ttgattttac caatgtggct caggccaaat ggtttagtat
    24961 cccatcagtg gaaattcctt tcttaaccta cggggttaaa ttctacccaa gtgccatttt
    25021 aactatggca cccattgcct ttgttacaat gacagaacat tttggacaca ttatggtctt
    25081 aaatagtttg acaaaaagag attatttcaa ggatccagga cttgaaaaga ctttaactgg
    25141 tgatggtttt gcgcaaatca ttgctggctt cttaggggca cctccggtca cttcttatgg
    25201 tgaaaacatc ggtgtaatgg ctctgaataa aatattctcg gtctatgtta ttgcaggtgc
    25261 cgcagtgatt gccgctctcc tcagttttat cggtaaggta tcagccttaa ttcaatctat
    25321 tccaacacca gttattggag gtatatcagt tgccttgttt ggtgtaatag cttctagcgg
    25381 tttgaaaatc ttgattgaat ccaaagttga tatggataat aagaaaaact tattgattgc
    25441 cagtgtcatt ttggtctctg ggattggagg attgatgctt caagtaaatg gtcttcaaat
    25501 ttcaggtgtc gctttctcaa cacttcttgg catcatctta tatcaggtac ttcctgaaaa
    25561 ataggaagaa ttgttgttag accacttaca tagtcatcag tcgttagtga taaaggggat
    25621 aatcatgtca gttgtaaata atcgcgttgc acttaccaat ttagtttcaa tggaagcatt
    25681 aaccaccgaa gaagttttag gtcttatcaa ccgtggttca gaatataagg ctggtaaggt
    25741 tgttatttcg gatcatcaaa aggatcttgt tgccaattta ttctttgaaa actccacccg
    25801 aacccataag tcttttgaag tggctgagaa gaaactcggc ttgacagttc ttgatttcaa
    25861 tgctgatgca agtgcggtta acaagggaga aagtttgtat gatactgtgt taaccatgag
    25921 tgcacttgga acagacatct gtgtgattcg tcacccagaa gatgattatt acaaggaatt
    25981 agtagaaagt ccaactatta cagcttccat tgtcaatgga ggagatggtt ctggacaaca
    26041 cccgagtcaa tgtttacttg acttattaac catctatgaa gaatttggac gctttgaagg
    26101 cttaaagatt gcgatcgctg gtgacttaac tcactctagg gtggcaaagt ccaacatgca
    26161 aatcctcaaa agattaggag cagagcttta tttctatgga cctgaagaat ggtattcaga
    26221 agcctttaat gcttacggca cttatattgc tattgaccag attattaagg aattggatgt
    26281 tcttatgttg ctgcgtgtac agcacgaacg tcatgacggc catcagagtt tttcaaaaga
    26341 aggttaccat caagcgtttg gattgacaca ggaacgttac caacaattaa aagattctgc
    26401 tattattatg catccagctc cagttaatcg ggatgtggaa attgcagata gtttggtgga
    26461 agctcctaaa gcgagaattg tatctcagat ggctaatggt gtctttgttc gcatggctat
    26521 tattgaagcc attttgaatg gtagaaataa aaactcatga tgaaagatta aagcatgttt
    26581 agaaggtagg aaaaggtagg aaaatgacaa aacgattact tattttagaa gacggcacta
    26641 tttttgaagg agaacccttt ggtgctgata ttgatgtgac tggtgaaatt gtctttaata
    26701 caggaatgac aggctaccaa gaatccatca ctgaccaatc ctacaatggg caaattttaa
    26761 cctttaccta tcctttgatt ggaaattatg ggattaatcg agatgactat gagtccattt
    26821 cacccacctg taaaggggtt gttgtgtctg aagtcagtcg gttggcaagt aattggcgca
    26881 agcaaatgac gctagatgcg ttcttgaaaa taaaagggat tccagggatt tcgggaattg
    26941 atacgagagc tttgaccaaa attattcggc aacacggtac catgaaagct acgatggcag
    27001 atgatggaga tagtatccag catttaaaag atcaactgcg tgcaacagtc ttaccgacta
    27061 acaccattga acaagtgtca actaaaacag cttatcctgc accagggatc gggaaaaata
    27121 ttgtattggt tgattttggt ttaaaacatt ctattttaag agaattttct aaaagacaat
    27181 gtaatatcac cgttgtccct ttcaacatca ctgcagaaga agtgctccaa ctaaatccgg
    27241 atggtttgat gctatctaat ggcccaggaa acccagaaga tttgccagag gctttagaca
    27301 tgattcgtgg ggtacaaggt aagattccta tttttggtat ttgtatggga catcaactct
    27361 ttagtctagc aaatggtgcc aagacttgta aaatgacctt tggtcatcgt ggctttaacc
    27421 atgccgttag agaaattgca acgggaagaa ttgattttac cagtcaaaac catggttatg
    27481 ccgttgaacg tagtagtcta cctgatactt taatggttac gcatgaagac attaacgata
    27541 agacggtcga aggagtgaaa catagagatt ttccagcttt ttcagtccaa tttcaccctg
    27601 atgcggctcc aggacctcat gatgccagct acttatttga cgaatttttg gaaatgattg
    27661 attcttggag atgtacgagt aaatagtaaa tcagttgcaa tttcacgact atatcacctc
    27721 ttgttactct atttattaac atttacagtt gatttagtac cctatcaaaa atattattta
    27781 atgttgctct gtgaggcaac aaatagagaa aggaaggcaa ggagaacaca agtaaataat
    27841 ttagtaaaaa gttaggtttt caaagagata aagctcttat tgagaagtgc tgactttacc
    27901 gcttcttgtg gtattcttgg tatcattaat tatgccaaaa cgaaaagata ttcaaaaaat
    27961 catggttatc gggtctggcc cgattattat tggacaagct gctgaatttg attatgcagg
    28021 gactcaggcc tgtttggctc taaaagaaga aggctataag gtcatacttg ttaattcaaa
    28081 tcctgcaacg attatgacag ataaagaaat cgctgataag gtatatattg agcctttgac
    28141 tcttgaattt gttaatcgta tcattcgaaa agaaaggcca gatgccatac tgccaacctt
    28201 aggtggtcaa acgggcctca atatggcaat ggcattatct aaagctggta ttcttgatga
    28261 tttagagatt gaattgttag gtactaagtt atctgcgatt gatcaggcag aagacagaga
    28321 ccttttcaaa caattaatgc aagaactaga ccaacccatt ccagaatcta caattgttaa
    28381 aacagttgat gaagctgtta catttgctag agatatcggt tatccagtca ttgtgcgccc
    28441 agcttttact cttggtggaa ctggtggagg aatatgtagt agtgaagaag aactttgtga
    28501 aattactgaa aacggcctaa agttatcacc ggtcacacag tgtttgattg aacgctcaat
    28561 tgctggcttc aaagaaattg aatacgaagt aatgcgagat agtgctgata acgcgctggt
    28621 tgtttgtaat atggaaaact ttgatcccgt agggattcac acaggagatt ctattgtatt
    28681 tgcaccaaca cagacccttt ctgatattga aaatcaaatg ttacgtgatg ctagtttaaa
    28741 aataattcga gctctgaaaa ttgaaggtgg ctgtaacgtc cagttagcac tagatcctta
    28801 tagtttcaaa tattatgtta ttgaagtaaa tcctagagtg tctcgttcct ctgcccttgc
    28861 ttcaaaagca acaggttatc ccattgccaa attggctgca aagattgctg ttggcctaac
    28921 acttgatgaa atgattaacc ctatcacagg cactacttac gctatgtttg aacctaccct
    28981 tgattacgtt gttgctaaaa ttccgcgttt tccgtttgat aaatttgaac atggtgaacg
    29041 ccaactggga actcaaatga aagcaacagg tgaagtcatg gctattggcc gtaatttgga
    29101 agagtcctta ctaaaagcct gtcgttcttt agaaattggt gtttgccata atgagatgac
    29161 aagtttaagt aacattagtg atgaagagtt agtgactaaa gtgattaaag ctcaagatga
    29221 tcgacttttt tacttgtcag aagcaatacg acgaggttat agtatcgaag aacttgagag
    29281 cttgaccaag attgatttat ttttcttgga taaattactt catattgttg aaatagagca
    29341 agatctacaa atgcatgttg agcatttgga aagcctcaaa aaagcaaagc gttatggatt
    29401 ttcagatcaa aaaattgcag aaatttggca aaaggatgaa agtgatatca gagcgatgag
    29461 acattctcat agcctgtatc ctgtctataa aatggtagat acttgtgcag ctgaatttga
    29521 tgctaaaacc ccttattttt attcaacata tgagttggaa aatgaatctg ttcagtcgaa
    29581 taaagaatca attttagttt taggttcagg ccctattcgt attggtcaag gggttgaatt
    29641 tgactacgca acggttcatt ctgttaaagc catccaaaaa gctggctatg aagccattat
    29701 catgaattca aatccggaga ctgtatctac agatttttcg gtatcagata aattatattt
    29761 tgaaccgtta acctttgaag acgtcatgaa tgtgatagat ttagagcagc ctaagggagt
    29821 aatagttcag tttggaggac aaactgctat taacttagca caagcacttt ctgaggcggg
    29881 tgttacaata ttaggaacac aagtagagga tttggatagg gctgaagaca gagatttatt
    29941 tgaaaaggcg ttgaaagagc ttggaatccc acaaccacaa ggtcaaacgg caactaatga
    30001 agaagaagca ttagaggcag ctaaaaaaat tggttttcca gtcttagtta gaccttctta
    30061 cgtacttggc ggccgggcta tggaaattgt tgaaaacaaa gaagatctta gagaatatat
    30121 aagaacagcg gttaaagcaa gtcctgaaca tcctatctta gtggactctt atattttcgg
    30181 taaggagtgt gaagtggatg ccatttcaga tggaaaatca gtcttaattc ctggtattat
    30241 ggagcacatc gaaagagcag gtgttcattc aggagattca atggcagttt atccgccaca
    30301 gcaattatct aagcaaattc aagaaacaat agctgagtat actaaacgtt tagccattgg
    30361 gttaaattgt attggtatga tgaatgttca atttgttatt aaaaatgaac aagtctatgt
    30421 tattgaagtg aatccacgcg ctagtcgtac cgtgcctttc ttatcaaaag taacaggtat
    30481 tccgatggct cagattgcta ctaagttgat tttaggtcaa acattaaagg atctaggata
    30541 tgaagatggt ctttatcccc aaagtcaact ggtgcatatc aaagcgcctg tgttttcatt
    30601 tacaaagttg gcacaggttg atagtctttt aggtcctgaa atgaaatcaa ctggagaagt
    30661 aatgggttcg gatactagtc ttgaaaaagc actttataaa gcgtttgaag ccaataattc
    30721 tcatttatca gaatttggtc aaattgtctt tactatagca gatgatagta aggcagaagc
    30781 tctaagtcta gcaagacgat ttaaggcgat tggctatcaa attatggcta ctcaaggtac
    30841 agcagcttac tttgctgagc aaggcttaag cgcgtgttta gttggaaaaa ttggtgatgc
    30901 tgccaatgac atcccgacac tcgtgcgaca tggtcacgtt caggcaattg ttaatacagt
    30961 tggaattaaa cgcacagctg ataaagacgg acagatgatt agaagttcag ctattgaaca
    31021 aggagttcct ttatttacag ctttagatac tgcaaaagct atgttaacgg ttttagaaag
    31081 cagatgtttt aacatcgaag cgatataaaa attaaaaaat catttttaag aaaacttaaa
    31141 aatgattttt ttagattata atgacaaaag tttcagtaag ctattaattt gtcatagcat
    31201 ataagtcatt atcttgtggc ttgttttcga ctaagggtta agaatttctt gacaacaata
    31261 taaaaaggtc atatacttgt cttatacaaa tagtacaaaa aggggaggat agaaatgtct
    31321 aaaagaggaa aaattaaaat aacaacgaaa acaaagctta ttacagctag tgttataacg
    31381 ctagtattaa ttataactgg agtagtcttg tggaaacaac aacaaaatac gctaacagct
    31441 gatatcgcta aagaacctta ctctactgtt agtgtaactg aagggagtat tgcttcttcg
    31501 actttactct caggtactgt aaaggcttta tcagaggaat atatttattt cgatgctaat
    31561 aaaggaaatg atgcaactgt tacagttaaa gtaggtgatc aggtaacgca gggccagcaa
    31621 ttagttcaat ataatacaac aacagctcag tcagcttatg atactgctgt taggagtctt
    31681 aacaagattg gccgacaaat taatcatctt aaaacatacg gagttcctgc tgttagtaca
    31741 gaaactaata aagatgaagc taccggtgaa gagacgacaa caacagttca accatcagct
    31801 cagcaaaatg ctaattataa acagcagctg caagatttaa atgatgctta tgcagatgca
    31861 caagcagaag taaataaagc gcagatagcg ttaaatgata cagtagttat cagtagtgtc
    31921 tctggaactg ttgtggaagt aaataatgat attgatcctt cttcaaagaa cagtcaaaca
    31981 cttgttcacg tagcaaccga aggacagctt caggtgaaag gaacattgac agagtatgat
    32041 ttagcaaacg ttaaggttgg tcaatctgta aaaattaagt ctaaagttta ttctaatcaa
    32101 gaatggactg gaaaaatatc atatgtttca aactatccaa ctgagtctaa tgcaggttca
    32161 acaacgccag caggtagcac tggagcggga agttctacag gagctgccta tgattacaag
    32221 attgatatta taagtcctct caaccagctt aaacaaggtt tcactgtttc tgttgaggtt
    32281 gttaatgaag ctaaacaggc cttagttcct ttaacggctg ttattaagaa agataaaaaa
    32341 cactatgttt ggacttatga tgatgctact ggcaaagcca aaaaagtaga ggtgacactt
    32401 ggaaacgcag atgcacaaca acaagaaatt cataaaggag tagctgttgg tgacattgtt
    32461 attgccaatc cagataaaaa tatcaaaccg gataaaaaac tagaaggggt tatttcaata
    32521 ggtaccaaca caaaaccgga aaaagattct caatcaaaga ataaaaaatc aggggtggat
    32581 aaatagtgtc gcatgaaaaa aaacaattaa tgcaattatc aaatattgtg aagagctatc
    32641 aaaatgggga tcaagttctt aaagttttga aaggtattaa tttaacagta tatgagggtg
    32701 aatttttagc tattatgggt ccgtctggct cgggaaaatc aacactaatg aatattattg
    32761 gtttattaga tcggccaaca tccggagatt acacattaca taatactaaa atagaaatcc
    32821 ttaatgatcg tgaattagca aaagtacgaa acgatgaaat cggctttgtc tttcaacaat
    32881 tctttctgtt agctaaatta actgcattac aaaatgttga gttgcctctt atttatgctg
    32941 gtgtaaacgt ctcaaaaaga cgtgaacagg ctaagcaatt tcttgaaaaa gtaggacttg
    33001 gacgacgtat caaacatcta ccgtcagaac tgtcaggagg tcaaaagcaa agggtggcta
    33061 tcgcacgagc tttagtaaat gacccatcta ttattttagc ggatgaacca acaggtgcac
    33121 tagatactaa aacaggtcag caaattatgg aactcttgac agagttaaac aaagaaggta
    33181 aaacaattat tatggttact catgaaccag aaattgctga ttttgcaact cggaaaatta
    33241 ttattcgtga tggtgatatc acaacggata ctacagctag tgttgttatt gactaggagg
    33301 aaaaataatg gaaaattgga aattcgctct tagctcaatt tgggggcata agatgcgctc
    33361 aatcctgaca atgttgggaa ttatcatcgg tgtagcagca gttgtgatta ttatggggtt
    33421 gggaaatgct atgaaaaata gtgtaacaag cacattttct agcaagcaaa aagatattca
    33481 actctatttt caagaaaaag gagaagaaga agacctgtat gccggattgc acacgcatga
    33541 aaataatcac gaagtgaagc cagagtggtt agaacaaatt gttaaagata tcgatggtat
    33601 tgattcttat tactttacca attctgctac ttctactatt tcgtatgaaa aaaagaaagt
    33661 agacaatgct tcgatcatag gggtaagtaa agattatttt aacataaaaa actatgatat
    33721 cgtagctggt cgtacactaa cagataatga ttattctaat ttttcgcgta tcattctttt
    33781 agatacagta ttagccgatg acctatttgg cgaaggtaat tataagtcag ctttaaataa
    33841 agtggtaagt ttatctgata aagattattt agttattggt gtttataaaa ctgatcagac
    33901 gccagtttct tttgatggat tatcaggcgg cgctgtcatg gcaaatactc aggtagcttc
    33961 agagtttggc accaaagaaa taggatctat ctacattcat gtgaacgata ttcaaaacag
    34021 tatgaactta ggaaatcaag cagctgatat gctaaccaac atatcgcata ttaaagatgg
    34081 acagtacgct gttcctgata atagcaaaat cgttgaagaa atcaatagtc agttcagtat
    34141 catgacaaca gtcataggtt caattgcagc gatctctctt ttagtgggag gaattggtgt
    34201 tatgaatatt atgttggtat ctgtcacaga gcgaactaga gaaattggtt tacgtaaagc
    34261 acttggtgca acacgcctga aaattttatc acaatttttg attgaatccg ttgttctaac
    34321 agttcttgga ggcttgatag gattattatt agctcaatta agtgtagggg ctttaggaaa
    34381 tgcgatgaca ttaaaaggag cttgtatttc tcttgatgtg gccttaatag cagttttatt
    34441 ttctgcctca ataggtgtct tttttggaat gttgccagct aataaagcta gtaagttaga
    34501 tccaattgag gcattacgtt atgaatagaa tagttcgtat caattaatct atagacgctg
    34561 actagtttaa cgtctgatta tatctagttt ttgtattagc acagtagtta tatcattgaa
    34621 gtgttagtgc attttttgag gtgataatat ctagcaaagc tatcattggt atgatgatgt
    34681 ggatagcgta taagtgatac atctcttatt tctagctgaa cttcggttcg gctaggaagt
    34741 tgtcaggcaa tgagttgttt aaaataaagg agattagttc aatgacattt ttatctgatt
    34801 tgatatcatt aatgacaaaa atcagattat cttgggtaat aaaggcgggt atttttcaat
    34861 tattatttgt aacgattgct aatattgtct tatcagaatt tttctatttt atattagacg
    34921 ttactggtca atatcattta gataaagaca atgttgtgac ttttttaaaa aatcctatag
    34981 cacttgcttt attaggtgcc tatttatttt tattagctgc ttttattcac cttgagtttt
    35041 ttgctctata tcgaattatt gcggatcaag aaattagttt ctatcttttt agaaaacagt
    35101 tttcttatta cctaaggggg ctttggaaaa cattttctgg ttaccaatta ttactttttt
    35161 tgctttatat cctattgact attccagtct tacatattgg tttatcttct gtgattactc
    35221 aaaagcttta tcttccagaa tttattgttg gggaattatc aaagataact agcacaaagt
    35281 acttgcttta tggcagtctt attcttgtat tttaccttaa cctaagatta gtatattttt
    35341 taccattgat agcaatcaac catcgtacgg ttgctcaagc atggagagag agttggcaaa
    35401 agactaaaaa gaaacatgta ttgttatgga tgaaactttt tgcaatcaat ggtcttacgc
    35461 ttgtagtcgt atcgctagct atttccatga ttcttatttt tgttgatatg tttaatccta
    35521 aggggaataa tattattgtt cagctgggag ctttgacctt tacatgggag ctcatttttt
    35581 ttactactat tttttttaaa ctctgttcag caatgatttt aaaagaggca attgaaccac
    35641 aaaagcaata tgatgagcca agaagaagta ataaggcata tgttgtaatc tttatcgtgg
    35701 tgacagtagg ttttgcttat caatctcttg aacgtttaac tttttttgac acatctcact
    35761 ctaagacagt tatcgcgcat agaggacttg tatcagcagg tgtagaaaat tctctggaag
    35821 cccttgaagg tgctaagaaa gcaggaagtg attatgtaga actggatcta atcttgacta
    35881 aggataatca ctttgtggtg tctcatgata atcgattgaa gcgtttagct ggagtaaata
    35941 agacgattcg caacttaacc ttaaaagaag ttgaacatct aacgagtcat caaggacatt
    36001 tttcagggcg ttttgtttct tttgacactt tttatcaaaa ggctaagaag ttgaatatgc
    36061 cattacttat tgaactcaag ccaattggta cagaacctgg aaattatgtc gatttgtttt
    36121 tagaaactta tcatcgactt ggtataagca aagataataa agtcatgtct ttagatttag
    36181 aagtaataga agctatcaag aaaaaaaatc catcaattac gactggttat atcataccaa
    36241 ttcaatttgg cttttttgga gatgaatttg ttgatttcta tgtcattgaa gacttttctt
    36301 atcggtctta tttgtcgtcc caagcttttt ggaataataa agaaatttac gtttggacta
    36361 ttaatgatcc caagcgcata gagcattatc tcctaaagcc tattcaggga attattacag
    36421 atcaaccagc tttaactaat caattgatta aagacttaaa acaagataat tcttatttta
    36481 gtcgattagt cagaattatt agtagtcttt attaaaggtt taaagaaagt gtcaagaaaa
    36541 aaacttgaca ctttctttaa actgagttat actgtttaac ataggaattt agcgtagctg
    36601 tatttcttat acattactaa aagaaaagag actatttaaa aatggcagta aaaatccgtt
    36661 taactcgtat gggttctaag aaaaaacctt tctaccgtat taatgttgca gattcacgtg
    36721 caccacgtga tggtcgtttt atcgaaacag ttggaacata caacccatta gtggctgaaa
    36781 atcaaattac tattaaagag gatcgtgttc ttgagtggtt atctaaagga gcgcagcctt
    36841 ctgataccgt tcgtaacatc ttgtctaaag ctggtgttat ggctaagttc cacgaccaaa
    36901 aattctctaa ataataacag cctatggata ccattgaaaa tcttattatc gctattgtga
    36961 aacctttgat ttcacaacca gataatctta ccattaaaat tgaagatact cctgactttt
    37021 tagagtatca tcttgacttg gatgctcaag acatcggtcg tgttatcggc aaaaaaggtc
    37081 gaactattac tgcgataaga tcgattgtct actcggttcc aacactagga aaaaaagttc
    37141 gcttagttat tgatgagaaa taatcactaa cttgagatgg attgaaaagc ttgttgactt
    37201 aaagtcaaca agctttttga atagcaaaaa tcttaatatt tctgaaatga aaagattaga
    37261 tttttctgtc tttaactaaa aagaagttaa agaatggctt agctgattgc ctttataaga
    37321 gattatactg gtttttgata gctgctgtca tgtaaaatag ctacaattca tcttacgaga
    37381 ttgaccttag cattgccagt gcagtcttta ttttctaacc tgctgtttgt tgtatgttta
    37441 tagtttccta aaaaatgctc tctcagtttt ttgggggaca ttcct
//
LOCUS       DATWEK010000015        37235 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.015, whole genome shotgun sequence.
ACCESSION   DATWEK010000015 DATWEK010000000
VERSION     DATWEK010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37235
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.015"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(74..1378)
                     /locus_tag="VCR92_000932"
     CDS             complement(74..1378)
                     /locus_tag="VCR92_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEP4268015.1"
                     /translation="MIISRSRGKTMKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSV
                     SLIQAHANPFKSVINQGVFWIISLVAITFIYKLKLNFLTNTRVLTVVMLGEAFLLIIA
                     RFFTTAIKGAHGWIVIGPVSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRK
                     WWPTQWNDLRDWRVYSLLMVLLVAAQPDLGNASIIVLTAIIMFSISGIGYRWFSAILV
                     MITGLSTVFLGTIAVIGVERVAKIPVFGYVAKRFSAFFNPFHDLTDSGHQLANSYYAM
                     SNGGWFGQGLGNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGFILALVFFLILRIMNV
                     GIKAKNPFNAMMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVA
                     VGFVLNIDASEKRDDIFKEAELSYRKDTRKENSKVVNIKQFQ"
     gene            complement(1518..4316)
                     /gene="ppc"
                     /locus_tag="VCR92_000933"
     CDS             complement(1518..4316)
                     /gene="ppc"
                     /locus_tag="VCR92_000933"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEP4268016.1"
                     /translation="MIEETSKEGDGHLPLKKLESSNNQAIIAEEVALLKEMLENITRR
                     MIGDDAFAVIESIMVLSEKQDYIELEKVVANISNQEMEVISRYFSILPLLINISEDVD
                     LAYEINYQNNTDTDYLGKLALTIKDLAGKDNGKDILEQVNVVPVLTAHPTQVQRKTIL
                     ELTTHIHKLLRKYRDAKAGVINLEKWRQELYRYIEMIMQTDIIREKKLQVKNEIKNVM
                     QYYDGSLIQAVTKLTTEYKNLAQKHGLELDNPKPITMGMWIGGDRDGNPFVTAETLCL
                     SATVQSEVILNYYIDKLAALYRTFSLSSTLVQPNSEVERLASLSQDQSIYRGNEPYRR
                     AFHYIQSRLKQTQIQLTNQPAARMSSSVGLSTSAWSSPASLENPILAYDSPVDFKADL
                     KAIEQSLLDNGNSALIEGDLREVMQAVDIFGFFLASIDMRQDSSVQESCVAELLKGAN
                     IVDDYSSLSETEKCDVLLQQLMEEPRTLSSAAVAKSDLLEKELAIYTTARELKDKLGE
                     EVIKQHIISHTESVSDMFELAIMLKEVGLVDQQRARVQIVPLFETIEDLDNARDIMAA
                     YLSHDIVKSWIATNRNYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTAIGEEHGVKI
                     TFFHGRGGTVGRGGGPSYDAITSQPFGSIKDRIRLTEQGEIIENKYGNKDVAYYHLEM
                     LISASINRMVTQMITDPNEIDSFREIMDSIVADSNTIYRKLVFDNPHFYDYFFEASPI
                     KEVSSLNIGSRPAARKTITEITGLRAIPWVFSWSQNRIMFPGWYGVGSAFKRYIDRAQ
                     GNLERLQHMYQTWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESQDVRDVFYEILDEW
                     QLTKNVILAIQDHDDLLEDNPSLKHSLKSRLPYFNVLNYIQIELIKRWRNNQLDENDE
                     KLIHTTINGIATGLRNSG"
     gene            4475..6274
                     /gene="pepF"
                     /locus_tag="VCR92_000934"
     CDS             4475..6274
                     /gene="pepF"
                     /locus_tag="VCR92_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEP4268017.1"
                     /translation="MELKKRSEFPENELWDLTALYKDRQDFLLAIEKALQDIDLFKRN
                     YEGRLTSVDDFTQALIEIEHIYIQMSHIGTYAFMPQTTDFSDESFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLDVLDTLEKNPYFSAAIRMAKIQKEHLLSPDVEKALANLREV
                     INAPYDIYTKMRAGDFDMEDFEVDGKTYKNSFVSYENFYQNHENAEIRDKAFRSFSKG
                     LRKHQNTAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSLFDRQIDLIMTEFG
                     PVAQKFLKHVAQVNGLEKMTFADWKLDIDNDLNPEVSIDGAYDLVMKSLAPLGQEYTK
                     EIERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEHQFDDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGADQLNAMMKEVLTDFWGDAVDIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKNNPDGAKEWLDFLKSGGSRTPLDTAMLIG
                     ADIATEKPLRDTIQFLSDTVDQIINYTEEMSHA"
     gene            6267..6746
                     /locus_tag="VCR92_000935"
     CDS             6267..6746
                     /locus_tag="VCR92_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEP4268018.1"
                     /translation="MPNLYDFTVKAQNGNDLSLAAYKKKVVLIVNTATKCGLTPQYQA
                     LQALYDTYHDKGFEVLDFPCNQFLNQAPGDAEEINHFCSLTYHTTFPRFAKIKVNGKD
                     ADPLFTWLKEEKSGPLGKRIEWNFTKFLIDQNGQVIKRYSSKTDPKLIEEDLKALLG"
     gene            complement(6793..7176)
                     /locus_tag="VCR92_000936"
     CDS             complement(6793..7176)
                     /locus_tag="VCR92_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HEP4268019.1"
                     /translation="MNKRFKTGFLALVAMLLVACSQGTKQTQTPSVPKADHHVRLVVK
                     EDTNTIDEKVSFGKGDTVLEILKDNYEVKEKDGFITAIDGIEQDTKANKYWLFKVNGK
                     MADKGADQITVKDGDSIEFYQEVFK"
     gene            complement(7160..7663)
                     /locus_tag="VCR92_000937"
     CDS             complement(7160..7663)
                     /locus_tag="VCR92_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEP4268020.1"
                     /translation="MSAKFMSRIAIMSALCVVLRMVFSSLPNVQPVTAFLLSYLLYFG
                     LAEAVLVMMLCLFLSAFLLGFGPWVFWQVTCFVLVLLLWRFALYPLSQQFPKYQLGYQ
                     AFLAALCGLLYGVLIDTCFAYLYSMPWWSYVLAGMPFNIAHALSTLVFFPVVMMLFRR
                     LIGEQKI"
     gene            7988..8836
                     /locus_tag="VCR92_000938"
     CDS             7988..8836
                     /locus_tag="VCR92_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEP4268021.1"
                     /translation="MRRKIKPIVVLVFFILLAMVLIIGKRQANHAKQKEVEDAKSHIP
                     IATSNPSKAKTSTSETEDFILNPIVDVSGWQLPEEIDYDTLSRHISGAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKTHIKEFQKRNVPVAVYSYALGRSTKEMKEEARAFYKNAAPY
                     NPTYYWIDVEEATMKDMNKGVTAFREELKKLGAENVGLYIGTYFMAEQDISTKGFDAV
                     WIPTYGSDSGYYEAAPNTTLDYDLHQYTSQGYLSGFNNALDLNQIAVTKDTKKTFEKL
                     FGNSNN"
     regulatory      8964..9060
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            9105..9668
                     /gene="thiT"
                     /locus_tag="VCR92_000939"
     CDS             9105..9668
                     /gene="thiT"
                     /locus_tag="VCR92_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEP4268022.1"
                     /translation="MSPNTNVKYLIEAAIFAALAMALSFIPDFAGWFSPSYGAIALVI
                     FSLRRGLKYGMLAGLIWGLLHFVLGKVYYLSMSQVFIEYILAFTSMGLAGSFSDSLIK
                     TLRRQQTFFAVFLAIMASLLAVTVRYLWHFLAGIIFWGSYAPKGMSAVWYSFSVNGTA
                     GVLTFLITCLALMIALPIHPQLFDPKD"
     gene            9758..10237
                     /locus_tag="VCR92_000940"
     CDS             9758..10237
                     /locus_tag="VCR92_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEP4268023.1"
                     /translation="MAKKTKFKKTLVEQILDKANIAHQGLKLNALEGDFPDDLQPSDI
                     YKTLALTGDQTGPLIGIIPLTEHLSEKQLAKVSGNKKVSMVPQKDLQKTTGYIHGANN
                     PVGIRQKHSYPIFIDQTALEKGQIIVSAGEVGRSIKISSQALADFVGASFADLKKRK"
     gene            10578..11201
                     /locus_tag="VCR92_000941"
     CDS             10578..11201
                     /locus_tag="VCR92_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEP4268024.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGAGGDSPLLEEAKDEIHLLGKELA
                     KVAFDAVYTSDLQRAMATAAIILDAFDQQPKLYHTDQLREWRLGKLEGAKIATMAAIY
                     PQQMLAFRENLAQFKSDQFEAESIYQTTQRVCHLIQSFKDKHYQNVLIVGHGANLTAT
                     IRSLLGFEPALLLAKGGLDNTSLTILETKDYLTYDCLIWNDKSFLEV"
     gene            complement(11309..12211)
                     /locus_tag="VCR92_000942"
     CDS             complement(11309..12211)
                     /locus_tag="VCR92_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEP4268025.1"
                     /translation="MITAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSVMNQAYIRFR
                     HYSDVGFPRVMAGEWTTEYFRFWRCKETLLEFGYREIDEAAGVHFQEVYEHELENITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLKKVRKLGLYDYIDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPQTTLYVGDSYDNDIMGAFNGGWHSMWFNHRGRQLKPGTKPVY
                     DVAIDNFEQLFGAVKVLFDLPDNKFIFDVNDKKNPILQMGINNGLMMAAERLLESNMS
                     IDKVVILLRLTKQQEKVLRLKYAR"
     gene            12385..13878
                     /gene="lysS"
                     /locus_tag="VCR92_000943"
     CDS             12385..13878
                     /gene="lysS"
                     /locus_tag="VCR92_000943"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEP4268026.1"
                     /translation="MSNQHIEELNDQQIVRREKMTALAEQGIDPFGKRFDRTANSAEL
                     KEKYADKTKEELHELNETAIVAGRLMTKRGKGKVGFAHLQDREGQIQLYVRKDSVGED
                     NYEIFKKADLGDFIGVEGEVMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRESFDRFVTRSKMISEIRRYLDGLDFLEVETPVLHNEAGGAAARPFV
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADYLDIMNLTEGIIQHAAKAVKGDGPIDYQGTEIRINEPFKRVHMVDAIKEVTGVD
                     FWPEMTVEEAIALAKEKQVPLEKHFTSVGHIINAFFEEFVEETLVQPTFVFGHPVEVS
                     PLAKKNPEDTRFTDRFELFIMTKEYANAFTELNDPIDQLSRFEAQAQAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            14014..14154
                     /locus_tag="VCR92_000944"
     CDS             14014..14154
                     /locus_tag="VCR92_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268027.1"
                     /translation="MTKEYISYISAAIFLLYGLLAAKWIFLGLGLILVLVGLADRLNS
                     KK"
     gene            complement(14251..14463)
                     /locus_tag="VCR92_000945"
     CDS             complement(14251..14463)
                     /locus_tag="VCR92_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEP4268028.1"
                     /translation="MAEFTFNIEEHLLTLSENDKGWTKELNRVSFNGAEAKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRK"
     gene            complement(14680..15966)
                     /locus_tag="VCR92_000946"
     CDS             complement(14680..15966)
                     /locus_tag="VCR92_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEP4268029.1"
                     /translation="MSHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHARGAKVYVAANMVTHEGNEIGAGEWFRQLRDMGLDAVIVSDP
                     ALIIICSTEAPGLEIHLSTQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSL
                     KGEIPEDYSMSSVDMCMIDHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKEELIDELWKVAQRELATGFYYGIPTENEQLFGARRKIPQYKFVGEVV
                     AFDSASMTATIRQRNVIMEGDRIECYGPGFRHFETVVKDLHDADGQKIDRAPNPMELL
                     TISLPREVKPGDMIRACKEGLVNLYQKDGTSKTVRT"
     gene            complement(16068..16994)
                     /locus_tag="VCR92_000947"
     CDS             complement(16068..16994)
                     /locus_tag="VCR92_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEP4268030.1"
                     /translation="MEKIIITATAESIEQVKALLAAGVDRIYVGEANYGLRLPHNFSY
                     DELRQIAKLVHDAGKELTVACNALMHQDMMDQIKPFLDLMIEIAVDYLVVGDAGVFYV
                     NKRDGYNFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSAELFTLAENLEFPAE
                     VLVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDASSHYSIYEDNHGTH
                     IFINNDIDMMSKLGELYAHGLTHWKLDGIYCPGDDFVAITKLFIQAKTLLEAGQFTQE
                     EAEKLDQAVHAHHPAGRGLDTGFYEFDPKTVK"
     gene            17193..17477
                     /locus_tag="VCR92_000948"
     CDS             17193..17477
                     /locus_tag="VCR92_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEP4268031.1"
                     /translation="MPAPLKKHNSVEQDDSYQESQSKFRDFQEFNGQSAKLKELVFFA
                     RIASFSLITVLFAFVLLVMNLAPMFAFLFASIISLGITSLFAKVIKSLLM"
     gene            complement(17637..18065)
                     /locus_tag="VCR92_000949"
     CDS             complement(17637..18065)
                     /locus_tag="VCR92_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEP4268032.1"
                     /translation="MNKSFKNLVIGAVSGVAAAYFLSTEKGKALKNRAEKAYQAYKES
                     PDDYHQFAKEKGSEYSHLARDTFYDVKDKLASGDLTKEDMLDLLKDKTTAFVQKTKET
                     LAEVEAKEKQDDVIIDLNEEDIIIDYTEQDEPVSDTLDKH"
     gene            complement(18058..18465)
                     /locus_tag="VCR92_000950"
     CDS             complement(18058..18465)
                     /locus_tag="VCR92_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEP4268033.1"
                     /translation="MDLVGISLMIIALAFVALVIFLIIVLKKVSETIDEAKKTISVLT
                     SDVNVTLHQTNDILAKANILVEDVNGKVATIDPLFVAIADLSESLSDLNSQARHFGQK
                     ATNATGNVSKAGKLALVGKVASKVFGKKGEKHE"
     gene            complement(18487..19266)
                     /locus_tag="VCR92_000951"
     CDS             complement(18487..19266)
                     /locus_tag="VCR92_000951"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEP4268034.1"
                     /translation="MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSD
                     AIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALVLL
                     AYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMF
                     IEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMR
                     TDSLMFLGIRISQYVSALLIIIGLIFVIKRRRQKGISYYQE"
     gene            complement(19263..20195)
                     /locus_tag="VCR92_000952"
     CDS             complement(19263..20195)
                     /locus_tag="VCR92_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEP4268035.1"
                     /translation="MTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQAA
                     KEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEDRLTQLITKNEVSQ"
     gene            complement(20560..20832)
                     /locus_tag="VCR92_000953"
     CDS             complement(20560..20832)
                     /locus_tag="VCR92_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEP4268036.1"
                     /translation="METKFYKQRKNRLVAGVIAGLADKYGWDLALARVLAALLIYGTG
                     FGVLLYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNEEEDGWFW"
     gene            complement(20896..21333)
                     /locus_tag="VCR92_000954"
     CDS             complement(20896..21333)
                     /locus_tag="VCR92_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEP4268037.1"
                     /translation="MTLTNYVQEVSLADFGKPFHHKAYWNKRLKTTGGRFFPKDGHLD
                     FNPRMLEEHGELIFRKIVRHELCHYHLYFEGRGYHHKDRDFKDLLAQVNGLRYVPTSS
                     KSKTNHHYSCQTCGQVYQRKRRINLAKYVCGNCHGKLMEKNQS"
     gene            complement(21320..23452)
                     /locus_tag="VCR92_000955"
     CDS             complement(21320..23452)
                     /locus_tag="VCR92_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEP4268038.1"
                     /translation="MENNNNHNIAEALSVSLHQIEQVLALTAQGNTIPFIARYRKEVT
                     GNLDEVVIKSIIDMDKSLTTLNERKATILAKIEEQGKLTDQLRTSIEATEKLADLEEL
                     YLPYKEKRRTKATIAREAGLFPLARLILQNAQNLETAAEPFVTEGFASPQEALAGAVD
                     ILVEAMSEDAKLRSWTYNEIWQYSRLVSTLKDEQLDEKKVFQIYYDFSDQVSNMQGYR
                     TLALNRGEKLGILKVSFEHNLEKMQRFFSVRFKETNPYIEEVINQTIKKKIVPAMERR
                     VRSELSDAAEDGAIHLFSENLRHLLLVSPLKGKMVLGFDPAFRTGAKLAIVDQTGKLL
                     TTQVIYPVAPASQTKIQAAKETLTQLIETYQIDIIAIGNGTASRESEAFVADVLKDFP
                     NTSYVIVNESGASVYSASELARHEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIG
                     VGQYQHDVSQKKLSENLGFVVDTVVNQVGVNVNTASPSLLAHVSGLNKTISENIVKYR
                     EENGALTSRADIKKVPRLGAKAFEQAAGFLRIPGAKNILDNTGVHPESYPAVKELFKV
                     LGIQDLDDAAKATLAAVQVPQMAETLAIGQETLKDIIADLLKPGRDLRDDFEAPILRQ
                     DILDLKDLEIGQKLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSKTFVNHPSQVVSVG
                     DLVTVWVSKIDLDRHKVNLSLLPPRDTH"
     gene            23686..23841
                     /locus_tag="VCR92_000956"
     CDS             23686..23841
                     /locus_tag="VCR92_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268039.1"
                     /translation="MAITHKKNDELEKMLAGFASIPSFDKPLEVNTDGKLATKEKTTE
                     QTKPSKP"
     gene            23989..24891
                     /locus_tag="VCR92_000957"
     CDS             23989..24891
                     /locus_tag="VCR92_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEP4268040.1"
                     /translation="MSLFSNLPPSVLQWFAIFMSIIIEALPFVLLGTILSGCIEVFVT
                     PELVQKYLPKQKCLRILFGTFVGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLILRLVGAALVAITLGVMLAFIVDDNILKDNAQPVHFH
                     DYSHESLPKRIYLALVHAIDEFFDTGRYLVFGTLIASAMQIYVPTRVLTTIGHNPLTA
                     ILIMMLMAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMVKTFKG
                     RFIVQFIGVSVLMIAVYCLLVGVL"
     gene            24891..25706
                     /locus_tag="VCR92_000958"
     CDS             24891..25706
                     /locus_tag="VCR92_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEP4268041.1"
                     /translation="MIRFLILAGYFELTMYLQLSGKLDQYINVRYSYLAYISMVLSFI
                     LALVQLYTWMKNIKVHSHLTGKIARLTSPFILVFPVLIGLLVPTVTLDSTTVSAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMRQELHKYKGKKPVTITTEN
                     YMEVMELIYLYPDEFLDRDIQYTGFVYNEPGHDNYQFLFRFGIIHCIADSGVYGLLTT
                     GNQTSYPNNTWLTVKGRLHMEYDKNLEQHLPVLQLTEVHQTKEPNNPYVYRVF"
     gene            complement(25805..27229)
                     /locus_tag="VCR92_000959"
     CDS             complement(25805..27229)
                     /locus_tag="VCR92_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEP4268042.1"
                     /translation="MGIFPKDFLWGGAVAANQVEGAFEADTKGLSVQDVLPNGGLGEW
                     TDSPTSDNLTLEAIDFYHRYKEDIALFAEMDFKVFRTSIAWSRIFPNGDDDQPNEAGL
                     QFYDDLFDELLNYGIEPLVTLSHYETPLHLAKAYNGWTDRRLIGFFERFAQTVMERYK
                     DKVKYWLTFNEVNSILHMPFTSGGIMTEKEKLSLQDLYQAIHHELVASASVTKLAHEI
                     NPDVKVGCMILAMPAYPMTSDPRDILAAHAFENLNLLFSDIHVRGKYPSYIKSYFKEN
                     GIEIVFEDGDKELLAEHTVDFLSFSYYMSVTQAHNPEAYTSGQGNILGGLSNPYLESS
                     EWGWQIDPIGLRLVLNQYYDRYQIPLFIVENGLGAKDQLVQTADGSMTVHDDYRIDYM
                     SQHLVQVAKAIEDGVEVMGYTAWGCIDCVSMSTAQLSKRYGFIYVDRNDDGTGQLTRY
                     KKKSFDWYRQVIQTNGRYLEDNFS"
     gene            complement(27248..29110)
                     /locus_tag="VCR92_000960"
     CDS             complement(27248..29110)
                     /locus_tag="VCR92_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEP4268043.1"
                     /translation="MTYQETAKAILAAVGGKTNIQRVTHCVTRLRLVLKNDEKVKDQQ
                     VKAISNVIGVMRKNGQYQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLI
                     ETIAGVITPLIPALLGGGMLKVVGILLPMLGLASADSQTVAFINFFGDAAYYFMPVMI
                     AYSAAARFKVTPVLAATIAGILLHPAFVAMVAEGKPLTLFGAPVTPASYGSSVIPILM
                     MVYLMQYIEKWVNRLVPSVMKSFLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLA
                     IYHVAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGA
                     ASLAVAFKTKQKQTRQVALAAGISALLAGITEPALYGVTLKFKKPLYAAMISGGLVGA
                     FIGFVNIASYTFVVPSIIGLPQYINPSGGANFINALIAGAATIVLAFSLTWFMGIDEE
                     SPKQVSVAADMSQVKSGLSTKQTLYAPMTGEMLFLSEVPDETFSSKLLGEGFAILPSE
                     GVVYAPFDGEVITFFPTKHAVALKNTRGVEVLIHVGIDTVELKGQGFEQLVSVGDVVK
                     RGQALLKMDIDFITSKGYSLISPVVVTNSAEQLEIIIQDDKKMVTKEDALLVIL"
     gene            complement(29112..29954)
                     /locus_tag="VCR92_000961"
     CDS             complement(29112..29954)
                     /locus_tag="VCR92_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEP4268044.1"
                     /translation="MLIKRVLNHNAAISTNHQGLDILLMGKGIAFGKKVGDSIELNAI
                     ETSFVLKNSDNMNRFTELFITVPQEVVACSERIINLGKIKLGKTLDEILYINLTDHIH
                     SAIERHEQGMLIHNPLRWEIQRYYPDEYSLGVKALELIERNLGVTLAIDEAAFIAMHF
                     VNASLDTPFKEPHRLTEIVSYIEQKIKTDFKTELDDTSIDYYRFMTHIKLFAQRVLSE
                     MSYDDDDAELLLVVKTKYPKEYRCVLDISEEIKKRYNYHLNSSELLYLTVHVKRLVKH
                     LKET"
     gene            30282..31649
                     /locus_tag="VCR92_000962"
     CDS             30282..31649
                     /locus_tag="VCR92_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP4268045.1"
                     /translation="MSHHQQTVSKQTIMAIIAIALIGFSGILSETSMNVTFPTLMSVY
                     QLPLNSLQWMTTIYLLAVAIMMTTSATLKKNVRERPLFFMATGLFTFGTILAVLTQSF
                     AIMLLARIFQGIGTGLVMPQMFNIILERVPMHKVGLFMGFAGLIISLAPAFGPTYGGF
                     MISHFSWQWIFICILPVPLIAGILAYYYLEDSPVSEKVPFDWLAFIALSISLTSALLA
                     ITSLENGSVNLYYLGLFILSFVLFLYKNLTAKQPFLDIRILKIPSLTFGLIPFFVFQL
                     INLGINFLTPNFIVMEKIANSSQAGMVLLPGTLLGALLAPAFGKLYDQKGAKLSLYLG
                     NALFSLSLIIMTLQTRHFMLLPFTLLYILFTFGRNMGFNNSLATAIRELPAEKNADAT
                     AIFQMMQQFAGALGTAMASLIANSQPEFTSGVQSVYLLFTIFALLDFIFFFAMFYHLG
                     KKGLA"
     gene            complement(31703..33253)
                     /gene="ftsY"
                     /locus_tag="VCR92_000963"
     CDS             complement(31703..33253)
                     /gene="ftsY"
                     /locus_tag="VCR92_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEP4268046.1"
                     /translation="MGLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQNK
                     IEVVQQEDVSSEGAGSVENGPEAASVNAQVEEETGDNSNHPSEDTNEFAADKTDLKVS
                     ELSQSTASEPKDLVDQPVVEQFPTKQAQADASNDSANEEAVDTSKEQSSSQQVMEDYY
                     RRKAALEKSLQEKAAATVPVMPEEVPQENQASTSAEASQNKATHDTIPETDQEKYKRS
                     LKKTRTGFSARLNSFFANFRRVDEEFFEDLEEMLILSDVGVHVATTLTEELRYEAKLE
                     NAKKPDALKRVIVEKLVDIYEKDGRYNEAINYQDGLTVMLFVGVNGVGKTTSIGKLAY
                     RYKQEGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVITGPEKADPASVVFDGMEKAVA
                     KGVDILLIDTAGRLQNKENLMAELEKMGRIIKRVLPDAPHETLLALDASTGQNALSQA
                     KEFSKITPLTGLILTKIDGTAKGGVVLAIRQELDIPVKFIGFGEKVDDIGEFHSEDFM
                     KGLLEGIL"
     gene            complement(33253..34077)
                     /locus_tag="VCR92_000964"
     CDS             complement(33253..34077)
                     /locus_tag="VCR92_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEP4268047.1"
                     /translation="MNIRILALDLDGTLYNTEKIVTDANKKALAAAREKGVKVVITTG
                     RPLKAIGNLLEELDLLDHDDYSITFNGGLVQRNTGEVLDKSSLSFDQVCQIQQALEAV
                     GLPTDIISGGDVYSIPSKDGRHSQYHLANPLLTFIEVTSVAELPKDITYNKIVTVTDP
                     DFLDQQIIKLSPSLFEDFEAFKSRDIIFEIMPKGIDKAFGLNLLCQHLGLDARHVMAM
                     GDEANDFAMLEWAGLGVAMANGVSGAKAVADAVTTLTNDESGVAEAVKTFILEEES"
     gene            complement(34081..34878)
                     /locus_tag="VCR92_000965"
     CDS             complement(34081..34878)
                     /locus_tag="VCR92_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEP4268048.1"
                     /translation="MIKLIATDMDGTFLAEDGTYNQEQLAALLPKLAEKGILFAVSSG
                     RSLLAIDQLFEPFLDQIAVIAENGSVVQYHGEILFADMMTKEQYTEVAKKVLANPHYV
                     ETGMVFSGQKAAYILKGASEEYIQKTKHYYANVKVINGFEDMENDAIFKVSTNFTGHT
                     VLEGSDWLNQALPYATAVTTGFDSIDIILKEVNKGFGMEHLCQALGIKKAETIAFGDN
                     FNDYQMLEFAGRAIATENARPEIKVISDQVIGHCNDGAVLTYLKGLV"
     gene            35182..36308
                     /locus_tag="VCR92_000966"
     CDS             join(35182..35416,35416..36308)
                     /locus_tag="VCR92_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612023.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEP4268049.1"
                     /translation="MSTVKRYDEEFKQSLVNLYQTGKTQSELCKDYGVSASALAKWIK
                     QYSQVKLEDNSVLTAKQIQELQKRNAQLEEENLIPKKSKCHIHAKLKVRLLAVYRLRF
                     EHDTTTLCRVLRVNRSTYYKFLKHKPSKRELDNQIYRKQILEIYTKANKRLGVKSIKV
                     ILQRDYDTKISEGRIYRLMKNMALPKMATVKPKTALKRTQKTYPQNLLNQKFNPDKPN
                     QVWSTDFTYISIGYKKYVYLCAILDLYSRKCIAWKLSHHMDAKLACDTLELALNKRKI
                     EGTLLFHSDQGSQFKARKLRKIIDDNTIMHSFSKPGYPYDNAVTEAFFKYLKHRQINR
                     KKYQNIKQVQLDCFEYIENFYNNYNPHTANLGLTPNQKEEN"
     gene            complement(36679..37058)
                     /locus_tag="VCR92_000967"
                     /pseudo
     CDS             complement(36679..37058)
                     /locus_tag="VCR92_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017516.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(37055..37235)
                     /locus_tag="VCR92_000968"
                     /pseudo
     CDS             complement(37055..37235)
                     /locus_tag="VCR92_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017515.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        11272 a         7884 c         6586 g        11493 t
ORIGIN      
        1 cagttcaagt tttttgagca tcaaactggg attgtctata ttctaaaatc tccttaaagg
       61 agattttaga atattattga aattgcttga tatttacaac tttactattt tcttttcgag
      121 tgtcctttcg ataagataat tcagcttctt taaatatatc atctcgcttt tcgctagcat
      181 caatatttag tacaaaaccc actgcaacag ataagacaag taagctattt ccaccttgag
      241 acaaaaaagg gaaggtaaca ccagtagatg gaattaagcc tgagatacca ccaatattaa
      301 caaagacttg catgagcatc ataccgccta ctcctaaagc catcatggca ttaaaaggat
      361 tttttgcttt aataccaaca ttcataatac gtaaaattaa gaagaaaaca agtgccaaaa
      421 taaaccctgc tcctattaga cctaactctt caatgacaac tgaaaagaca aagtctgtct
      481 gtgcttcggg caaatagcca cgcttttcaa tggaatttcc taacccttgg ccaaaccacc
      541 caccattact catagcatag taagaattgg ctaattggtg acctgaatcg gtcaagtcat
      601 gaaaaggatt aaaaaaggca ctaaaacgtt tagcgacata gccaaaaaca ggaatcttag
      661 caactctttc taccccaata acggcaatag tcccaagaaa gaccgtagat agaccggtaa
      721 tcatgactag gatagccgaa aaccatcggt aaccaatgcc actgatagaa aacataataa
      781 tggctgtcaa tacaataatg gaagcatttc ctaagtcagg ctgagcagca accaaaagta
      841 ccatcaacaa agaataaaca cgccagtccc gtaaatcgtt ccattgtgtt ggccaccatt
      901 ttcgacgagt tagtgcttga taatcataaa ggctaatgtt tttttggatc ttagcaaagg
      961 tcaatgccaa ataccatacc ataatgatct ttaaatactc agcaggctga aagctgactg
     1021 gtccgatcac aatccaacca tgcgctcctt tgatagcagt tgtaaagaag cgggcaataa
     1081 ttaaaagaaa ggcctctcct aacataacca cagttaatac ccttgtattc gttaaaaaat
     1141 ttaattttaa tttatagata aatgtaatag ccactagact tattatccaa aaaactccct
     1201 ggttaatcac cgatttaaat ggattagcat gtgcttgaat caagctgaca cttgtggttg
     1261 agtaaaccat tattaagcct atcaccgata aaattaaata aggcaataat atagaataat
     1321 ttaagaggtg ccttttatca atcttcatag ttttccctct acttcttgag ataatcattt
     1381 agcattataa catctttcta tatcaaacaa aagaaaaagt caagaatcct caaaaaaaga
     1441 agctccaagg gctaaccttt aaaattctga ttagtcactt gaaaacttct ataaatacca
     1501 attaatactc aagagcatta gcctgaatta cgtaaaccag tcgctatgcc attgatagtt
     1561 gtatggatca atttttcatc attttcgtca agttgattat tacgccaacg tttaatcaat
     1621 tcaatttgaa tatagttcaa cacattaaaa tacggcaagc gtgacttcaa gctatgctta
     1681 agggaaggat tatcctccaa tagatcatca tggtcttgga tagcaagaat aacatttttt
     1741 gtcaattgcc actcatccaa aatttcataa aaaacatctc gaacatcctg actttcagct
     1801 agttgtgcat actgaaaggc aatattcatg tttgatttag ataataccat atcaacattt
     1861 gataacaagg aatggaaaaa aggccacgtc tgatacatgt gttggaggcg ttcaaggtta
     1921 ccttgtgctc ggtcaatata acgtttaaag gctgaaccta ccccatacca acctgggaac
     1981 atgatgcgat tttgtgacca tgaaaagacc caaggaatgg cacgcaagcc tgtaatttcc
     2041 gtaatcgttt tacgggctgc tggtcttgac ccaatgttga gactggaaac ttccttaatc
     2101 gggcttgcct caaagaaata atcatagaaa tggggattgt caaaaaccaa ttttcgataa
     2161 atggtattgc tatcagcaac aatgctatcc atgatttctc gaaaactatc aatctcatta
     2221 ggatctgtta tcatttgagt caccatacga ttgatagaag ctgaaatcaa catttctaaa
     2281 tggtaataag ccacatcttt attgccgtat ttgttttcaa taatttcccc ttgctctgtc
     2341 agacgaatcc gatctttgat ggaaccaaaa ggttgtgaag taatggcatc ataagaaggg
     2401 ccacctcctc gaccaactgt tcctccacga ccatggaaga aggtgatttt cactccatgt
     2461 tcctcaccaa tagccgttaa ttcattctga gctttataaa gagtccaacc cgatgccaag
     2521 tagccaccat ctttattact gtcagaatag cctaacatga tttcttggta attacgattc
     2581 gttgcaatcc aagatttgac aatgtcatgg cttaaatagg ctgccatgat gtcacgggca
     2641 ttatctaaat cctcaatggt ttcaaagagg ggaacaattt gcacacgagc ccgctgctgg
     2701 tcaaccaatc ccacttcttt aagcataatg gccaactcaa acatatcaga gacactttct
     2761 gtatgtgaaa taatatgttg ctttataacc tcttctccaa gcttatcttt caattctcgt
     2821 gccgtagtat agatagccag ttctttttct aataggtctg atttagcaac tgccgctgag
     2881 gataaagtcc ttggctcctc cattaattgt tgtaagagaa catcgcattt ttcagtttct
     2941 gaaagagagc tataatcgtc aacaatattg gctcctttta ataactctgc cacacaagat
     3001 tcttggacac tggagtcttg cctcatgtca atgcttgcta agaagaagcc aaaaatatca
     3061 acagcttgca tgacttctcg caaatccccc tcaatcaaag cggagttgcc attatcaagt
     3121 agcgactgct caatagcctt tagatcagct ttaaaatcaa caggagagtc ataggctaag
     3181 atgggatttt ctaaactagc tggtgaagac caagcagatg tgcttagtcc cacactacta
     3241 ctcatacgag ctgctggctg attagttagt tgaatttgtg tttgtttaag acgcgattga
     3301 atataatgaa aagctctgcg ataaggttca tttccacggt aaatcgattg gtcctgagac
     3361 aaactggcta aacgttccac ttccgagttg ggttgtacca aggtcgacga cagtgaaaat
     3421 gttcggtaaa gggctgctaa tttgtcaatg tagtaattga ggataacctc actttgaacc
     3481 gtagctgaca agcacaaggt ttcagctgtg acaaaggggt tcccatcacg gtccccacca
     3541 atccacatcc ccatggtaat gggtttggga ttgtctaact ctagaccgtg tttttgggct
     3601 aagtttttgt actctgttgt caacttggtc actgcttgaa tgagagaacc atcgtaatac
     3661 tgcatgacat tttttatctc gtttttcacc tgaagctttt tctcgcgaat aatatctgtc
     3721 tgcatgatca tttcaatata acgatatagc tcctgacgcc atttctcaag attaatcaca
     3781 ccagccttag catcacggta tttgcgcaga agtttatgaa tgtgagttgt caattccaga
     3841 atcgttttac gttgtacttg cgtcggatgt gctgttaaaa caggaaccac attaacctgc
     3901 tccaaaatgt ctttaccatt atcttttcca gcaagatcct tgatggttag ggctaatttt
     3961 cctaaataat cagtatccgt attattttga taattgattt cataggctaa atcgacatct
     4021 tctgaaatat tgattagcaa gggtaaaata gaaaaatacc tggaaatcac ttccatttct
     4081 tgatttgaaa tattggcgac aactttttct aattctatgt aatcttgttt ttcagataac
     4141 accataatag actcgataac tgcaaacgca tcatctccaa tcatccgtcg tgtgatattt
     4201 tccaacattt ctttcaaaag agcaacttct tcagcaatga tagcttgatt gttactactc
     4261 tctaactttt taagtggcaa atgaccatct ccttctttgc tagtttcttc tatcatacca
     4321 ctttttacca aaaataaaag tgatcatgtt aaaaacgttt gttttttaac aaaagtaagc
     4381 gctttatttt aaagaatgtt tggataggtt tagtctccat attccactaa aattctgtta
     4441 tactagtctt gactatattg ttaaggagac aactatggaa ttgaaaaaac gttcagaatt
     4501 ccctgaaaat gaactttggg atctaacagc gctctacaaa gaccgccaag attttttact
     4561 cgctattgaa aaagccttac aagatattga cctgtttaag cgcaattatg aaggccgctt
     4621 aacgtcggtg gacgatttca ctcaggcctt aatagaaatt gagcatattt atattcaaat
     4681 gagtcatatt ggcacttatg cctttatgcc tcaaaccact gacttttcag atgaaagttt
     4741 tgctcaaatt gctcaggctg gcgatgattt catgactaaa gctagcgttg cccttagctt
     4801 ctttgacacc gccttagcca atgccgacct tgacgtgtta gatacattag aaaagaaccc
     4861 ttatttcagc gcagctattc gcatggcaaa aattcaaaaa gaacacctct taagtcctga
     4921 tgtggaaaag gctttggcta acttacgcga ggttatcaat gcgccctatg atatttacac
     4981 caaaatgcgg gctggtgact ttgacatgga ggattttgag gtggatggta aaacctataa
     5041 aaatagcttt gtttcttacg aaaatttcta tcaaaatcac gaaaatgctg agattcgtga
     5101 caaagccttc cgctcttttt caaaaggtct ccgtaaacac caaaatacag ctgcagcggc
     5161 ttacttagcc aaggttaaat ctgaaaaatt gttagcggat atgaaaggct acgcttctgt
     5221 ctttgattac ctcctagctg aacaggaagt ggatcgtagc ttattcgacc gccaaattga
     5281 cctcatcatg actgaatttg gaccagttgc tcagaaattc ttaaaacatg tcgcccaagt
     5341 caatggtctt gagaaaatga cttttgctga ctggaagcta gatattgaca atgatctcaa
     5401 tccagaggtc agcattgatg gtgcctatga cctcgtgatg aaatctctag ccccattagg
     5461 gcaagaatac acgaaagaaa tcgaacgtta tcagacagaa cgctgggttg actttgctgc
     5521 taacgccaat aaggattctg gtggctatgc cgctgatccc tacaaggttc atccgtatgt
     5581 cttaatgagt tggactggaa gaatgtctga tgtttatacc cttattcatg aaatcggtca
     5641 ctctggtcaa ttcatttttt cagataatca ccaaagttac ttcaacaccc atatgtcaac
     5701 ttattacgtc gaagcgccat cgacctttaa tgaattgatg cttagtgatt acttggaaca
     5761 tcaatttgat gaccctcgtc aaaaacgttt tgcccttgct caccgtttaa cagacactta
     5821 ctttcataac ttcatcactc acctattgga agcggctttc caacgtaagg tttacaccct
     5881 gattgaagaa ggcggtacct ttggagctga ccaattaaat gcgatgatga aagaggtctt
     5941 aacagacttc tggggagatg ccgttgacat cgacgatgac gcagctctta cctggatgcg
     6001 ccaagcgcat tactacatgg gcttatatag ttatacctat tctgctgggc ttgttatttc
     6061 aacagctggt taccttaacc ttaaaaacaa cccagatggg gcaaaagaat ggcttgactt
     6121 cctaaaatca ggtggcagcc gtacgcctct cgatactgca atgctcattg gggcagacat
     6181 tgccaccgaa aagcctcttc gagataccat tcaattcttg agtgataccg ttgaccaaat
     6241 tatcaattac accgaggaga tgtcacatgc ctaatctcta tgattttacg gttaaggctc
     6301 aaaatggaaa tgacctttcc ttagctgctt ataaaaaaaa ggttgttttg attgttaaca
     6361 cagctaccaa gtgtggatta accccacaat accaggccct gcaagcacta tatgacacat
     6421 accatgacaa gggatttgag gtcttagatt ttccttgcaa ccaattttta aatcaagctc
     6481 caggagatgc tgaggagatt aatcactttt gcagtctgac ctatcacact actttccctc
     6541 gctttgctaa aatcaaagtg aatggtaaag acgctgatcc tttgttcacc tggttaaaag
     6601 aagaaaaaag tggtcccctt gggaaacgca tcgaatggaa tttcactaaa tttctcattg
     6661 accaaaatgg tcaagtcatt aaacgctatt cctcaaagac agatcctaaa ctaattgaag
     6721 aagaccttaa agcacttctt ggttaatata aaatagactt ggcgtgccaa gtctattttg
     6781 tattaatagt tactatttaa aaacttcttg ataaaattca atgctatcac catctttaac
     6841 ggtaatttga tcggcaccct tatctgccat ctttccattc accttaaaaa gccagtattt
     6901 gttagctttc gtgtcttgct caataccatc aattgctgtg ataaagccat ctttttcttt
     6961 gacctcataa ttatctttga gaatctcaag caccgtatct ccttttccaa aagaaacttt
     7021 ttcatcaatg gtattggtat cttctttgac aactaagcga acgtgatggt ctgcttttgg
     7081 aacgcttgga gtctgtgttt gttttgttcc ttgcgagcaa gcaacaagta gcatagcaac
     7141 aagcgctaga aatcctgttt taaatctttt gttcaccgat taacctccta aataacatca
     7201 tcacaactgg aaaaaagacg agagttgata aagcatgcgc tatattaaag ggcatccctg
     7261 ctaaaacata actccaccaa ggcatactat acaaatacgc aaaacaagta tctatcaaca
     7321 ccccataaag gaggccacat aaggcggcca agaaagcctg ataaccaagc tgatatttgg
     7381 ggaattgctg agacaaaggg tacaaggcaa aacgccataa taaaagaaca agcacaaaac
     7441 aagtaacttg ccaaaagacc caagggccaa atcccagcaa aaaggctgat aaaaacaagc
     7501 acaacatcat aactaataca gcctcggcta acccaaagta aagaagataa ctgagtaaaa
     7561 atgccgtcac aggctgcaca ttaggcaggc tgctaaaaac cattctcaac acaacacata
     7621 gggctgacat gatagcaatg cgactcataa acttagctga cataaacttc ttcctcgttt
     7681 ttttctctat tatgacagat ttacagagcg tttaccagtt tgaagctcac ttatttatca
     7741 aatgataata acatgagaat taaataacaa aacagtactt gctgactgtc atgatatagt
     7801 caaagactaa actaatattg taaagaatat agctaccaac tataagagat agtgacataa
     7861 acttgacata gttagagagg atctcatttg taacttataa aagataatac cttaaaatgc
     7921 aagataatat aagaaaacag ttaggatatt ttgatttttt ttagtaatta gggtacaata
     7981 acagttaatg agaagaaaaa taaaacctat tgttgtgcta gtcttcttta ttttactggc
     8041 aatggtattg attatcggaa aaagacaagc taatcatgcg aaacaaaaag aagttgaaga
     8101 cgctaagagt catattccta ttgcaaccag taatcctagt aaagcaaaaa ctagcacttc
     8161 tgaaaccgaa gactttattt taaatcctat tgttgatgtt tccggctggc aactccctga
     8221 agaaattgat tatgacacat tgtcacgtca catctctggc gcaattgtac gtgtctatgg
     8281 aggatcgcaa attacagctc ataacaacgc tgcttttaca actggaattg acaaatcttt
     8341 taaaacgcat atcaaagaat ttcaaaaacg aaatgttcct gtagctgttt acagttacgc
     8401 acttggtcgt agtactaaag agatgaaaga agaggcccga gctttctaca aaaatgctgc
     8461 tccctataat ccaacttact actggattga tgtcgaagaa gccactatga aagatatgaa
     8521 taaaggcgta acagccttcc gagaagagct taaaaaactt ggtgctgaaa atgttggtct
     8581 ctatattgga acttatttta tggcagaaca agatatttca acaaaaggtt tcgatgctgt
     8641 atggattccg acttatggta gtgattctgg ctattatgag gctgctccta atacaacctt
     8701 agattacgat ttacaccaat atacctcaca aggttatctc agtggtttta acaatgcttt
     8761 agatttaaat caaattgccg taacaaaaga cactaaaaaa acgtttgaga agttatttgg
     8821 caactccaac aattaagagg ttagcatcat ggctaatctt tttttatagt ttacatctta
     8881 ccaagaaaaa ctctaggtca ataatttaaa accccttatc cttgacaagg agattatctc
     8941 atcatataat gaaagcacta taatatttca caaaggagtg ctttggctga gatcgcaatt
     9001 gcgaaatcct gaggacctga tcttgttagt acaagcgtag ggattgtgac caataatcaa
     9061 tgattggaaa gcgatactct ttttgtgcac aaaaggagtt ttttatgtca ccaaacacca
     9121 atgtcaaata ccttatcgaa gctgctattt ttgctgcact ggcgatggcc ctttcattta
     9181 ttccagattt tgctggctgg tttagtcctt cttatggtgc tattgcactg gttattttct
     9241 ctttgcgccg tgggttaaag tacggcatgt tggcgggtct catttggggg ctgcttcact
     9301 ttgtacttgg aaaagtttac tatctcagca tgtcccaagt ctttattgaa tatatcttag
     9361 cctttacctc tatgggatta gccggtagtt tctctgatag tttgattaaa actttaagaa
     9421 gacaacaaac cttttttgcc gtttttcttg caataatggc tagtttacta gccgttacag
     9481 tacgttactt gtggcacttc cttgcaggaa tcattttctg gggcagttac gcccctaaag
     9541 gcatgtccgc tgtctggtat tcttttagcg ttaatggtac agctggtgtc ctaacttttt
     9601 taataacatg tttagcgtta atgattgctt taccaattca tcctcaatta tttgatccca
     9661 aagactaatt tttagtcatt tgaatcttac attaaaaaaa tggtataata atgttgttat
     9721 accatttttt atgtttagat aaaggtaagg acttgatatg gctaaaaaaa caaaattcaa
     9781 aaaaacctta gtagaacaaa tcctcgataa ggctaatatt gctcatcaag gactcaagct
     9841 taatgcttta gaaggcgact ttccagatga tcttcagcca tcagatattt acaagacact
     9901 tgctctgact ggtgatcaaa caggtcctct aattggcatt attccattaa cagaacactt
     9961 atcagaaaaa caattggcaa aagtatcagg taacaaaaaa gtgtccatgg ttcctcaaaa
    10021 agacttgcaa aagacaacag gctatattca cggtgccaat aatcctgttg ggattcgtca
    10081 aaaacattca tatcctattt ttattgacca aactgcactg gaaaaaggtc aaataatcgt
    10141 ttcagctggt gaagttgggc gttctataaa gatttctagc caggctctag ctgatttcgt
    10201 tggcgcaagc tttgctgatt taaagaagag aaaatgaaca ctactgccaa ctttatctgg
    10261 tttctttttt aagtttttcg ccttgattaa gctagtcttt gtttagtatt attttgatct
    10321 caactgcttt aacattgatc ctgttaatct ttttcttttg taaaggcttg atatcacgac
    10381 aaattcaggt cgatttgtct taaatctaat atgggcttta cactttaatc agaacctagc
    10441 tattatacac ttatactacg cttttttact ttatcttttc actataggta ttatttttgc
    10501 ttggtgatgc ctaaactttt tctggttact tttttatttt tagcgctcgc atcagttatc
    10561 tctaaaagga ggcttaaatg aaattatatt ttgtaagaca tgggaaaacc ctttggaatt
    10621 tagaaggtcg ctttcaaggc gctgggggcg attcgccatt acttgaagag gcaaaagacg
    10681 aaattcactt acttggcaaa gagttagcta aggtggcttt tgatgccgtt tatactagcg
    10741 accttcaaag agctatggca acagcagcta ttatcttaga tgcttttgac caacagccaa
    10801 aactttacca caccgaccag cttcgggagt ggagattagg taaattggaa ggggctaaaa
    10861 tagcaacaat ggcagctata tatccccaac aaatgctggc ttttcgggag aatctagccc
    10921 agttcaaatc agatcagttc gaggctgaat caatttacca aacgactcaa cgtgtctgcc
    10981 atcttatcca atcgtttaaa gataaacatt atcaaaacgt tcttattgta ggacacggcg
    11041 ctaacttaac agcaactatt cgctcattat taggttttga acctgctctt ttactcgcta
    11101 aaggtggctt agataatacc agtcttacta ttcttgaaac taaggattat ttaacttatg
    11161 actgtttaat ttggaatgat aaatcctttc tagaggtgta aaaccactag acaataataa
    11221 aaaaagctaa cacattgatt tcttactgac aagacactca ctttgctagc tttttttatt
    11281 attatctagt gggctattat ggtttcatct atctggcata ttttaagcgc aaaacttttt
    11341 cttgctgctt ggttaaccga agcaagataa ccaccttgtc aatgctcatg ttactttcaa
    11401 gtaaacgctc tgctgccatc atcaagccat tattgattcc catctgtaaa attggatttt
    11461 tcttgtcatt gacatcaaaa ataaatttat tatcaggtaa atcaaagagt actttaacgg
    11521 caccaaagag ctgttcaaag ttatcaatag ccacatcata aacaggctta gtgcctggtt
    11581 ttagctgacg acctctatga ttaaaccaca tggaatgcca accaccatta aaggcaccca
    11641 tgatatcatt gtcataagag tccccaacat atagtgtggt ttgtgggttc atgtcaaatt
    11701 gttctgctgc caggttaaaa atttcttttt ctggtttttg aaagcctgtt gcttggctca
    11761 caatgacacg cttaggatca atataatcat aaagccctaa tttacgaact tttttcagct
    11821 gatgttctgt gggcccattg gtaataatcc ccataggaac attctttgat tttaaaaagt
    11881 caagggtcat acgcatctca tctaacatgg taatgttctc aagttcgtgc tcatagactt
    11941 cttgaaaatg tactcccgca gcttcgtcga tttctcgata gccaaactca agcagtgttt
    12001 ccttgcaacg ccagaatcgg aaatattctg tggtccactc ccctgccatt actcttggga
    12061 atccaacatc tgaatagtga cgaaagcgaa tataagcttg attcattact gacatatcaa
    12121 aatctgggaa gcacttttcc atggcgattc gataaggcgc ttgctggtcg taaattgtgt
    12181 catccacatc aaaaacaata gcagtaatca tgagtctctt ttcttttcta gtttaatatc
    12241 ccaatcatta tactattttc cattaggctt ttcaatttca ttttcaaaaa aatgccccgc
    12301 tgcagtcgca ttttccaacg aaatataggt gtattctagc cccttttatg atacaatgga
    12361 aaggaaatcg tattggagga aaatatgtct aatcaacaca tcgaagaatt aaatgaccaa
    12421 cagattgtcc gtcgtgaaaa aatgacggcg ctggctgaac aaggaattga tcctttcggt
    12481 aaacgctttg accgcacagc caattctgct gaattaaaag aaaagtatgc tgataaaaca
    12541 aaagaagaat tacatgagtt aaacgaaaca gctattgttg ctggccgctt gatgacaaaa
    12601 cgtggcaaag gtaaggttgg ttttgctcat cttcaagacc gtgaaggcca aatccaactt
    12661 tatgttcgca aggactctgt tggcgaagac aactatgaaa tcttcaaaaa agccgattta
    12721 ggcgacttta tcggcgttga gggcgaagtc atgcgtacag acatgggcga gttgtcaatc
    12781 aaggcaacca agttgactca cctttctaaa tcacttcgtc ctcttcctga aaaattccac
    12841 ggattaactg atattgaaac catttaccgt aagcgtcacc ttgatttaat ttcaaatcgt
    12901 gaaagctttg accgcttcgt gacccgttcc aaaatgattt cagaaatccg tcgttattta
    12961 gacggtcttg atttcctaga agtagaaacg cctgtgcttc ataacgaggc tggtggtgct
    13021 gctgctcgtc ctttcgttac tcaccataat gctcaaaaca ttgatatggt tcttcgtatc
    13081 gcaacagaac ttcatttgaa acgtttgatt gttggtggta tggaacgtgt ctatgaaatt
    13141 ggtcgtatct tccgtaacga gggaatggat gctactcata atcctgagtt cacttctatt
    13201 gaggtttacc aagcctatgc agactatctt gatatcatga acctgacaga aggcattatc
    13261 caacatgctg ctaaagctgt taaaggtgat ggccctattg attatcaagg aactgaaatc
    13321 cgtatcaatg aacctttcaa acgtgtccac atggtagatg ctatcaagga agtgacaggt
    13381 gttgatttct ggcctgaaat gactgtcgaa gaagctattg cacttgccaa agaaaaacag
    13441 gtcccactcg aaaaacactt cacaagtgtc ggacatatca tcaatgcttt cttcgaagaa
    13501 ttcgttgaag aaaccttggt ccaaccaacc tttgtgtttg gtcatcctgt tgaagtatcg
    13561 cctttggcta agaagaatcc agaagatacc cgcttcaccg accgcttcga acttttcatc
    13621 atgaccaaag aatacgccaa tgctttcaca gagttgaatg atcccattga ccaattatct
    13681 cgttttgaag cacaagcaca agccaaagaa cttggtgatg acgaagcaac tggcattgac
    13741 tacgacttcg ttgaagctct tgaatatggt atgccgccaa ccggtggact cggaatcggg
    13801 attgatcgtc tttgcatgtt attaacaaac acaacaacaa tcagagatgt gcttttattc
    13861 ccaacgatga aaccttaact tttttaagat ttgtattcat atcttaaaac cgataagtgg
    13921 caatataaca taacgtttta ttatctctaa ccagtcttca ttaccatgaa gactggttta
    13981 ttaacagtag cttatagaaa gtgacttaac aagatgacca aagaatatat ctcctacatt
    14041 agtgctgcta tcttcttgct ttatggcctt ttagctgcca aatggatttt tcttgggcta
    14101 ggcttaattt tggtacttgt cggccttgct gatcgcctca attcaaaaaa ataatccttc
    14161 tattcgcccc tgtcctttta acctagcgat gtcatcacca ggttaaaagg acaagggcga
    14221 acgagggatt atgtttcgat taaggtaaca ttacttacga aaagcgtcta agatggtttt
    14281 aaattcttca ttagtaagag taatgccttt ccccattttc gtatggtctg gactccacgt
    14341 gcggatatcc catttcgctt ctgcgccatt aaagctgacg cggttcaatt ctttcgtcca
    14401 acctttatca ttttctgata aggtgagtaa atgttcctca atgttgaatg taaattctgc
    14461 cattagtttt cctcctcatc tatactattc gaaattaaag tggaaaaaat catctttttt
    14521 tcactttttt tatgactcat tctcctatta ttctatcaag ttttgagaaa ataagctatt
    14581 gtgatatcca attttcaaaa aaaaaaaaaa acaggctctc ttttcccaac tatggtcgta
    14641 taccatttgg aaaaagaggg cctctaatat ttcttgttac tatgttctaa cagttttact
    14701 ggtgccatct ttttgataga ggttgacaag gccttccttg caagccctaa tcatatcccc
    14761 tggcttaact tctctcggta aagagatggt taagagttcc attggatttg gggcacggtc
    14821 aatcttttgg ccatccgcat catgtaagtc cttaacaacc gtttcaaaat gacggaaacc
    14881 tggtccataa cattcaatcc gatcgccttc catgatgaca ttacgctgac gaatggtcgc
    14941 tgtcatgcta gctgagtcaa aggcaactac ttctccgaca aatttatatt gtggaatttt
    15001 gcggcgagca ccaaataatt gttcattttc agttgggata ccataataaa aacctgtagc
    15061 caactcgcgc tgggcaacct tccacaactc gtcaatcaat tcctctttga tagcataaaa
    15121 agcttctggg ctttccatgt aagcatctac agccgccttg taacagttgg ttacggttga
    15181 gacgtagtgg atagatttca ttcggccttc aatttttaag ctatcaaccc cattttcaat
    15241 caggtcagga atatggtcaa tcatacacat gtcaacagag gacatagaat agtcttctgg
    15301 aatttcccct tttaaggagc ggcgctctcc tccaaatggc atgtcataca aatcatactt
    15361 ccagcggcaa gactgtgagc agccgcccct gttggcatca cggtgactca tgtggtttga
    15421 caaaacacag cggcctgaat aagaaataca catggctcca tggacaaagg cttcaatttc
    15481 cacatctgtc cgcttacgga tttctgctaa ctcggccata ttaacctcac gagctaaaac
    15541 aactcgggtc aaacccatgg ctttccaaaa ttcaaaggtc tcgtaattgg tagatgaagc
    15601 ttgcgttgac aaatgaattt ccaaacctgg ggcttctgtt gaacaaataa taatcaaggc
    15661 tggatctgaa acaatgaccg catcaagccc catatcacgc agttgacgaa accactcgcc
    15721 cgcaccaatt tcgttccctt cgtgggtaac catgttggca gcaacataga ccttagctcc
    15781 acgcgcatgt gcataatcaa tgccttcttg caattcttcc atagagaagt taccagcgcg
    15841 gcttcttaga ccataggcct gtcctccaac aaaaacagca tctgcgccat agtcaatcgc
    15901 aacttttaat ttttcaagtg ttccagcagg tgataagacc tcgggacgtt ttttcatatg
    15961 tgacatgtga tattctttct attttcaaga taggtagatt acctgtgtaa tggtgtcata
    16021 accctgtctt gccctgaaat agtaaactca ctcaagacaa ggattactta tttaacggtt
    16081 tttggatcga actcataaaa gccagtatct aatccacggc cagctggatg atgggcatgc
    16141 actgcttgat caagcttttc agcttcttct tgggtaaatt gcccagcttc taataaggtt
    16201 ttagcctgaa taaacaattt agtaatagcg acaaaatcat cacctggaca gtaaatgcca
    16261 tctagcttcc aatgagttaa gccatgcgca tacagctcac ccaatttaga catcatgtcg
    16321 atatcgttat taatgaaaat atgagtgcca tgattgtctt cataaatgga gtaatggctg
    16381 ctagcatctc ctggttctgc caagaaaagt cctcgttcac gactaacctc atcatcaatc
    16441 tttgtaaaat ggtaataatt ttctagcaag gggcgtttcg agtgatgaat caccgaggcg
    16501 ccgtaaacta gcacctctgc tggaaattcc aaattttcag ctaaggtgaa taactctgct
    16561 gatgggattt cccttgctaa aacactttca acagcaccat gttgccccca gaaatttacc
    16621 tgacggctag aagtcacaaa aacagaggta tcataaatca gtttaaagtt atagccatcc
    16681 cttttattga cataaaacac acctgcatca ccaaccacaa gataatcaac agcaatctct
    16741 atcattaagt ctaaaaaggg tttgatctga tccatcatat cttgatgcat caaagcattg
    16801 caagctactg tcaactcttt gcctgcatca tgcactagtt tggcaatttg tctcaattca
    16861 tcataagaaa aattatgggg aaggcgtaac ccgtaattgg cttcaccaac ataaatacga
    16921 tcaacaccag cagctaataa agctttgact tgctcaatgc tttcagctgt ggctgtaata
    16981 attatttttt ccatataagc tttattatac caaaaatttt aagaccttaa gcatatttct
    17041 tgcaaaagcc caaacgttaa gctagtcccc ttactgttat agcatgataa gtcacttgtc
    17101 attagtaaat cttttcaaat cttttaaaaa aagatgacaa gaagagactt ttatgataga
    17161 attacttagt atgttaagga aaggagagga ctatgcctgc accgttaaag aagcataatt
    17221 cggttgaaca ggatgattct taccaagaat ctcaaagtaa atttcgagat tttcaagagt
    17281 tcaatggcca aagtgcaaag ctaaaagaat tagtcttctt tgctcgtatc gctagtttca
    17341 gccttattac cgttttattt gcatttgtcc tgctcgtaat gaatttagcg ccaatgtttg
    17401 ctttcttatt tgcaagcatc atcagcttag gcattacttc cttattcgcc aaggttatca
    17461 aatcattact gatgtaactt ccagagtccg ttttacgtga ctcttttttt tgtgtcaaaa
    17521 acaaaaaaag attgaagcca caatcccccc cttcttcagt tagcctaaaa ctaaccatcg
    17581 ggactagtga tcagatcctt caatcttttc ttcttctatg ttttaggtcg ttttagttag
    17641 tgtttatcta gtgtatcact aacaggctca tcttgttcag tatagtcaat gatgatgtct
    17701 tcttcattta aatcaatgat aacatcatct tgcttttctt tcgcttcaac ttcggcaagg
    17761 gtttcttttg ttttttgcac gaaagctgtt gttttatctt tgagcaagtc taacatgtcc
    17821 tctttagtta agtcaccaga agccaactta tctttcacat catagaaagt gtcacgtgct
    17881 aaatggctgt attcactacc tttttcttta gcaaattggt ggtaatcatc tggactttct
    17941 ttgtaggctt gataagcttt ttcagcacga tttttcaaag ccttgccttt ttctgttgat
    18001 aagaagtaag ctgccgctac tcctgaaaca gctccaatca ctaagttttt gaaactttta
    18061 ttcatgcttt tctccttttt ttccaaatac ttttgaggct actttaccaa ctaatgctaa
    18121 ttttccagct tttgaaacat tacctgtagc attagttgct ttttgcccaa aatgccttgc
    18181 ttgactattt aaatctgaaa gactttctga caaatcagca atagcaacaa acagtggatc
    18241 gatggttgct actttaccat taacatcttc aacaaggata ttagcttttg ctaaaatatc
    18301 attagtttga tgaagtgtca cattaacatc acttgtcaat acagaaatcg tttttttggc
    18361 ttcatcaatt gtttctgaga ctttctttaa tacaataatc aagaaaatca ccaaagcaac
    18421 aaatgcgagt gcaataatca tcagtgagat tccaactaag tccataagtt tctccttttt
    18481 ctatccttat tcttgataat aagaaattcc tttttgacgg cgtcttttta tgacaaagat
    18541 taagccaata ataattaata aggcagacac atattgggag atgcgaatac ctaaaaacat
    18601 aagactatct gttcgcatac cttcaatgac tagtcttcca ctaccatacc aaattaagta
    18661 aaatgcaaag atttctccat ctaatagact ttttggctta cgacgccaca tcataataat
    18721 gacaaatccc aaaagattcc aaagtgattc atagagaaag gtcggaatgc ggtaacttcc
    18781 ctctataaac atttgctttt gaataaagct tggtaagtaa tttaactggc tcacagcttt
    18841 accataggct tcttggttga taaaatttcc ccagcgaccg atagcttgag cgaccatgac
    18901 acttggtgcg gcaatatcta aaaaatgaat gggattgagc accttgttat aacagtaagc
    18961 caaaagtaca agagctcctg taatgagacc gccataaata gcaataccgc cattccaaat
    19021 ggctatgatt tcatctaaat gcttgacata ataagaccat tcaaaaataa catagtaaat
    19081 tcttgcacca acaatagcaa gtggaaaagc aatcagaata aaatcgaaaa tagcgtcaga
    19141 tgatattcct tttttgggtg cttcttttga tgctaagtaa accgccaaaa caagtcctga
    19201 caagatacat agcgcatacc agtggatggc tagtggacca cattttaagg caatgggatt
    19261 gatcattgac tcacctcatt tttggtgatt agttgagtta aacgatcttc aaaagttttt
    19321 gtagcatcaa agcccatttc tttagcccga tgattcatcg cagcggcttc aataaccact
    19381 gaaacatttc gacctgtttt taccggaata cgaatacgag ggattctcac tcctgagaaa
    19441 gttatctcct cattaccgtt tccgagacga tcaaaaactt taccagcctc aaagttttca
    19501 aggtaaatgg ccaattgaac ttgtgatgag tccttcacag cactagctcc ataaagcgac
    19561 atcacatcaa taatacctac cccacgaatt tcaagcaagt ggcgcaagat ctctgctggc
    19621 tctccccaaa gggtttcttc atctttggca tagacatcca cacggtcatc tgcaaccaaa
    19681 cgatgccctc gcttaactaa ttctaaacca gtctcacttt taccaattcc agaatcccct
    19741 tggataagaa cccccatacc ataaatatcc attaaaacgc cgtgaacact agtacgttca
    19801 gctaaagaag cgtcaagaaa ataagacatt tctccagcta agcggctagt tgaaacacgg
    19861 ctacttaaaa gtgaaatacc ttcttctttt gcagcttgaa ccatttcttt tggaatggct
    19921 aaatttctag agacaaccac tgcaggagtg tcctttttga acatctcttt taaaacagaa
    19981 taacggttgt gagaagtcat ctgtgtaaga taagaccact ctttcattcc aaatagctgc
    20041 aacctttctg gagcataata atcaaaataa ccagtcattt caagacctgg acgtgaaata
    20101 tctgatgttg ttatctcttt tgacaacaag ttatctgtag cataaaccac atcaagttta
    20161 actttttgca ctagcatctt tacagtaacg gtcataattt ctcctttttc aatattataa
    20221 cacaaatcga ccgttagacc cttgcaaata ctcatttttt cactactaaa tgagaacaac
    20281 gacaccaaaa atggtcttag ctctattaaa aactaggttt tatcatttag agatatgagt
    20341 caaaaataag acaatggcaa acaaatactt tactagtatc attgagcaat tagtgcttat
    20401 tatggtgttt aaaaaggtat catcttacta agtcaaaaag caaaaagcct catcatagct
    20461 gataagaccc ctcgcttact tacatatcaa aacattttat tatcatcagt taatcacatg
    20521 gttgctctta cgtgatgaat tatcatttta actgattgtt taccagaacc agccatcttc
    20581 ttcttcattt aagacatcag cgtctttacg acgacgagga cctcggccat aacgttcttc
    20641 aagcaagtct tccttgtaag gtaagaagat ggccaacaaa atataaagca aaactccaaa
    20701 accagttccg taaataagaa gagccgctaa gacacgcgct agagcaagat cccaaccata
    20761 cttatctgct aaaccagcaa taacacctgc aaccaagcga ttttttcgct gtttatagaa
    20821 tttagtttcc acgtttcttt acctcctcat tctatgatac tagtttacat tgtttttcgc
    20881 aaaataaaac cagtcttacg actgattttt ttccataagt ttcccgtggc aatttccaca
    20941 aacatattta gccagattga tacgcctttt tcgttgataa acctgcccac aggtttggca
    21001 actataatga tgattagtct ttgatttaga gctagttggg acataacgaa gcccgtttac
    21061 ttgagctagc agatctttga aatccctatc tttatgatgg taccctcttc cttcaaaata
    21121 aagatggtaa tggcagagct catggcgaac aattttccga aaaataagct caccgtgctc
    21181 ctcaagcatc ctagggttaa aatccaaatg accatctttt ggaaaaaagc gaccgccagt
    21241 tgtttttagg cgcttgttcc aataagcctt gtggtgaaat ggtttgccaa aatcagccag
    21301 ggaaacttct tggacataat tagtgagtgt cacgcggtgg caataggctg agattgacct
    21361 tgtggcggtc caagtcaatc ttagagaccc aaacagttac caagtcaccc actgaaacaa
    21421 cttgactagg gtggttgaca aaggttttgc tcatttcaga aatgtgaata agcccatctt
    21481 catgaacacc aatgtctaca aaagcaccaa agtcaacgac gtttctcaca gttccttcaa
    21541 gcttctggcc aatttccaaa tctttcaaat caaggatatc ttgacgtaag attggtgctt
    21601 caaagtcatc acgaaggtca cgacctggtt taaggagatc agcaatgata tctttaaggg
    21661 tttcctgccc aatagccaat gtttctgcca tttggggaac ttgaactgct gctaaagttg
    21721 ccttggcagc gtcgtccaag tcctgaatac caagtacctt aaagagttct ttgactgctg
    21781 ggtaggactc ggggtgaact cctgtgttat ctaaaatatt tttggctcct ggaattctga
    21841 gaaaacctgc tgcttgctca aacgccttag ctcctaaacg cggcactttt ttgatgtcag
    21901 cgcgtgatgt caatgctcca ttttcttcgc ggtatttgac aatattttct gaaatcgttt
    21961 tgttcaaacc tgacacatgt gctaataaag atggactagc cgtgttcaca ttaacaccga
    22021 cttggttaac cacagtatcc acaacaaaac caagattctc actcaacttt ttctgactca
    22081 catcgtgctg gtactgaccg acgccaatag atttaggatc aattttaacc aattctgcta
    22141 gtgggtcttg caagcgacga gcaatagaaa tagcagagcg cttctccact gtgaggtctg
    22201 gaaactcatg acgggctaac tctgacgctg aataaaccga agcaccgctt tcgttaacga
    22261 tgacatagga cgtatttggg aaatctttca aaacgtctgc tacaaaggct tcactttccc
    22321 gactggctgt tccgtttcca atggcaataa tatcaatctg gtaagtctca atgagctgag
    22381 tcagtgtttc tttagctgct tgaatcttcg tttggctagc tggtgctacg ggataaataa
    22441 cctgagtagt caacaatttt ccagtctgat caacgatagc caattttgca cctgttcgaa
    22501 aggcagggtc aaacccaaga accattttcc cttttaaagg agacactaac aaaagatgac
    22561 ggagattttc agaaaagagg tggatagccc catcttctgc ggcatcactg agttctgaac
    22621 gaacccgtct ttccatagct ggaacaattt tctttttgat ggtctgattg atgacctctt
    22681 caatataagg gttggtttct ttgaaccgca cactgaaaaa gcgttgcatt ttctccaggt
    22741 tatgctcaaa agacactttt aagatgccta acttttcgcc acggttaagg gctaaagtac
    22801 gatatccttg catgttagac acttggtcag aaaaatcgta atagatttgg aaaacctttt
    22861 tctcatccaa ctgctcatct ttaagcgttg atactaaacg gctgtactgc caaatctcat
    22921 tgtaggtcca agagcgtaat ttagcatctt ctgacatggc ctccacaaga atgtccacag
    22981 ctcctgctag agcttcttgt gggctggcaa atccttctgt gacaaagggt tctgctgctg
    23041 tttcaaggtt ttgcgcattt tgtaaaatca aacgtgctaa tgggaacaag cctgcttcac
    23101 gcgcaatcgt cgcttttgta cggcgttttt ccttataagg caggtacaac tcttccaaat
    23161 cagcgagttt ttcggttgct tcaatactcg ttcgtaactg atctgtcagt tttccctgtt
    23221 cctcaatttt agcgagaatg gttgctttgc gctcattcag ggtagtgaga gacttatcca
    23281 tatcaataat ggacttaatc accacttcat ctagatttcc tgttacttct ttacggtaac
    23341 gtgcaataaa gggaatggta ttgccttgtg ctgttagggc aagcacctgt tcaatttgat
    23401 ggagactaac tgacaaagcc tctgcaatgt tgtgattatt gttattttcc ataatattgc
    23461 tattataaca caaaccatgt taatgcaaaa aatgatagcg aaacattgtc ctaatataaa
    23521 gttgcgtaaa gaatcaaaaa aagctacttt tagtaaataa ctgacgaaac cctaaataac
    23581 aatacctaat tttaaaaaag aaagaagtaa acagcacttc cgctttggca ttgttctcaa
    23641 atgatagtat aatagactta tcttgaatga aagaaggtca tagatatggc aattacccat
    23701 aaaaaaaatg atgaacttga aaaaatgcta gcaggctttg catcaatccc tagttttgat
    23761 aagcctttgg aagtcaatac tgatggtaaa ctagcgacca aagaaaaaac gacagaacaa
    23821 acaaaaccaa gcaaaccata gctagtttgt ctcattctct taacatatcg tccattcgtt
    23881 taaactgagt tgagagattt ttagcgatca ggctaacaaa acgtatcagt cgaggctgaa
    23941 cattcgtgtt tcagcctcct cttttatcat ctagaaagga tatggtgaat gtcactcttt
    24001 tccaaccttc ctcccagtgt cttgcaatgg tttgcgattt ttatgtccat tatcattgaa
    24061 gctcttcctt ttgtgctcct aggaactatt ttatctggtt gtattgaagt ctttgtaacg
    24121 ccagaattgg ttcaaaaata cctacctaag caaaaatgct tgcgcattct gtttggaacc
    24181 tttgttggat ttgtttttcc ttcttgtgaa tgcgggatta ttcccatcat caaccgcttt
    24241 ttggaaaaaa aggtgcctag ttatacggcc gtcccttttc tggcaacagc gcctattatt
    24301 aatcctattg ttttgttcgc tacttattct gcttttggga attctttgcg ctttctgata
    24361 cttcgcttgg tcggtgctgc actagtagcc attacacttg gggtaatgtt agcttttatt
    24421 gtagatgata acattctcaa ggataatgct caacccgtgc attttcatga ttattctcat
    24481 gaaagcttgc caaaacgcat ttatctagca ctggtacatg ctattgatga attcttcgac
    24541 accggtaggt atctcgtatt tggaaccttg attgcctctg ccatgcaaat atatgtccca
    24601 actcgtgtgt tgacaacgat tggacacaat cccttgacag ccattttgat catgatgctg
    24661 atggctttca ttctatcatt atgtagtgaa gccgatgcct ttatcggagc ttccttatta
    24721 tccacctttg gagtggctcc agttcttgcc tttcttttaa ttggtcctat ggtggatatt
    24781 aaaaacctta tgatgatggt aaagactttt aaaggacgct tcattgtcca atttatcggc
    24841 gtatccgttc ttatgattgc cgtttattgt ttacttgtgg gggtgctcta atgattcgct
    24901 ttttaatttt agctggctat tttgaactaa ccatgtatct ccagctgtct ggcaaactgg
    24961 atcagtacat caatgttcgg tattcttacc ttgcttatat ttccatggtt ttatctttca
    25021 ttttagctct tgttcaactc tatacctgga tgaaaaacat taaggtacat agccatttaa
    25081 ccggaaaaat cgcaaggctg accagtcctt ttatcttggt ctttcctgtt ttgattggtc
    25141 tccttgtgcc gaccgtaacc ttagattcca ccacggtttc tgccaagggt tacacttttc
    25201 ctttggctgc gggagcctct aaaacgggag tcagtgatga cgggaccacc attcaatacc
    25261 tcaaacctga taccagcctt tactttacaa agtctgccta ccaaaaggag atgcgtcaag
    25321 aactccataa atataaaggc aagaaaccgg tcaccattac cactgaaaat tatatggaag
    25381 tgatggaatt gatctatctc tacccagatg agtttcttga tcgtgacatc caatacactg
    25441 gctttgttta taacgaaccg ggccatgaca actaccaatt ccttttccgc ttcggcatta
    25501 ttcactgtat tgccgactca ggagtgtacg gacttttgac cacaggtaat caaaccagct
    25561 accctaacaa cacatggcta acagttaaag gtcgccttca tatggaatat gataaaaact
    25621 tagaacaaca tctacctgtc cttcaactta ctgaggttca tcaaaccaaa gagcctaata
    25681 atccttatgt ttaccgcgtt ttttaaagac taataaaaaa gcacttgttt tttatcaaaa
    25741 caaatgcttt ttgagtttta tcagttagca taggaacaga gtcaccatct taaacaagac
    25801 ctatttagga aaaattatcc tcaaggtaac gtccattggt ttgaatgact tgtcggtacc
    25861 aatcaaacga ttttttctta tagcgtgtga gttgaccagt accatcatca tttcggtcaa
    25921 cataaataaa accgtaacgc ttacttaatt gggctgttga catagagaca caatcaatac
    25981 agccccaagc agtgtaaccc atgacctcaa cgccatcttc aatcgctttg gcaacttgca
    26041 cgagatgctg actcatgtag tcaatgcgat aatcatcgtg aaccgtcatg ctgccatctg
    26101 cggtttgcac cagctgatcc tttgcaccta agccattttc aacaataaac aaaggaatct
    26161 ggtagcggtc atagtactga ttcaagacca atcgcagacc aattgggtct atctgccaac
    26221 cccactccga agattctaaa tatggattgg acaaaccacc tagaatattt ccctgaccag
    26281 atgtgtaagc ttcaggattg tgggcttgtg tgacactcat gtaatagcta aaggatagaa
    26341 aatcaaccgt atgttccgct aataattcct tgtctccgtc ttcaaaaaca atctcaatcc
    26401 cattttcttt aaaatacgac ttaatatatg aaggatactt gcctctcaca tgaatatctg
    26461 aaaataagag attaagattt tcaaatgcat gcgcagcaag tatatcacga ggatcagagg
    26521 tcattgggta agcaggcatc gccaaaatca tacacccaac tttaacatca ggattgattt
    26581 catgcgctag ctttgtgaca ctagcagatg ctaccaattc atgatgaata gcttggtata
    26641 aatcttgcag gctcagcttt tctttttctg tcatgatgcc accactggta aagggcatgt
    26701 gtaaaatcga gttgacttcg ttgaaggtca accagtattt gactttgtcc ttatagcgtt
    26761 ccatgactgt ctgagcaaag cgctcaaaaa agccaatcag acgtctatct gtccaaccat
    26821 tataggcttt ggccaaatgc agaggtgtct cataatgcga caaggtcact aagggttcga
    26881 taccatagtt caacaattca tcgaataagt catcatagaa ttgcaaacct gcttcattgg
    26941 gctggtcatc gtcaccattt ggaaaaatac gagaccaagc aatagatgtt cgaaagactt
    27001 taaagtccat ctcggcaaaa agagcaatgt cttctttgta gcggtggtaa aaatcaatcg
    27061 cctctaaagt taaattatcg ctggtaggac tatctgtcca ttctcctagt ccaccatttg
    27121 gtagaacatc ttgtacggac aaaccttttg tgtctgcctc aaatgctcct tccacttggt
    27181 tggcagctac tgcgccgccc cataagaaat cttttggaaa aattcccatt ctccctctcc
    27241 ttttaggtta taaaatgact aacaaagcgt cctctttagt caccattttt ttgtcatctt
    27301 gaataataat ctccaactgc tcagccgaat tggtcacgac cacaggactg atgagtgaat
    27361 agccttttga agtaatgaaa tcaatatcca tttttagaag tgcctggcct cgtttcacga
    27421 catcgccaac agacactaac tgctcgaaac cttgcccttt taactcaacc gtatcaatac
    27481 cgacatgaat caagacttcc acaccacgtg tgttttttaa ggcaacagca tgcttggttg
    27541 gaaagaaagt gatgacttca ccatcaaagg gggcatagac cacaccttcg cttggtaata
    27601 tggcaaatcc ttctcctaat aacttggaag aaaaggtttc atcaggaact tctgatagaa
    27661 aaagcatctc acctgtcatt ggagcataca acgtttgttt ggttgacaag ccgctcttaa
    27721 cttgtgacat atctgctgca acactcactt gctttgggga ctcttcatca attcccatga
    27781 accaagtcaa actgaaggct aacacaatcg tcgcagctcc ggcaatcaaa gcatttataa
    27841 aattagctcc gcctgatggg ttgatgtact gtggtaaacc aataatagaa ggtacgacaa
    27901 aggtataaga agcaatattg acaaaaccaa taaaggctcc aaccagacca cctgaaatca
    27961 tggctgcata gagtggcttt ttaaatttca gtgtgacccc ataaagtgcc ggttccgtga
    28021 tacctgccag caaagctgaa atccccgcgg caagggcaac ttgacgtgtt tgtttctgct
    28081 ttgttttaaa ggcaacagcc aaagatgcgg ctccttgagc caaattagaa gccaacattg
    28141 ctggtaaaat caagacatct ggtgttgcga ccgaagcggc caaaaagatt ggtgcaaaag
    28201 cccagtgcat ccccgtcatg acaacaagcg gcataatcgc tcccaaaatg gcaagtgcta
    28261 gccacggagc cacatgataa atagcgagca tggtattaga taacccttga ccaataatca
    28321 caccaagagg acctacaacc actaaagcca aaaagccaga aatcaaaatg attaaggttg
    28381 gctgtaagaa gcttttcatc acgcttggca ccaagcgatt gacccatttt tcaatgtatt
    28441 gcatcaagta aaccatcatc aaaatgggaa taacagatga gccatagcta gcaggagtga
    28501 ctggtgctcc aaataaagtc aatggtttac cttctgctac cattgcaaca aaggcaggat
    28561 gcaataaaat ccctgcgatc gtcgctgcta aaacaggtgt caccttaaag cgcgccgctg
    28621 ctgaataggc aatcatgaca ggcataaaat aataagccgc atcgccaaag aagttaataa
    28681 aggcaacggt ttgagagtcc gcactcgcta agccaagcat aggaagcaag attcccacca
    28741 ctttgagcat tccaccacca agaagggctg gaatcagcgg tgtaatcacg ccagcaatgg
    28801 tttcaatcaa gcgctcaagg atacttcctt tcgcttttga agaatgatct tcatcttgat
    28861 tgtcaaaatg ccctaggctt aaaaaggctt ggtaataatt attgacatca ttgcccaaga
    28921 taatttggta ctggccgttt ttgcgcatca cgccaatcac atttgaaatg gctttgactt
    28981 gctgatcttt aactttctca tcatttttca gtactaagcg tagacgtgtt acacagtgtg
    29041 tcacacgttg aatatttgtt ttgccaccaa ccgccgctaa aatagccttg gcagtttctt
    29101 gatacgtcat attaagtctc ctttaaatgt ttcactaaac gtttaacatg aaccgtcaaa
    29161 tacaaaagtt cgcttgaatt aaggtggtag ttgtaccgct tttttatctc ctcactaata
    29221 tctaagacgc accggtattc tttagggtat ttcgttttca ccactaaaag cagttccgca
    29281 tcatcatcat cgtaagacat ctctgataac acacgttgag caaataattt aatatgggtc
    29341 ataaagcggt aataatcgat ggatgtgtca tccaattctg ttttgaagtc tgttttgatt
    29401 ttttgctcaa tataagaaac aatctccgtc aggcgatgtg gctccttaaa aggagtgtcc
    29461 aaactagcat tgacaaaatg catggcaata aaagctgctt catcaatagc tagagtgact
    29521 cctagattac gctcaattag ctctaaggct tttaccccta gactatattc atcaggataa
    29581 tagcgttgaa tttcccaccg tagtgggtta tgaatcaaca ttccttgctc atgcctttca
    29641 atagcagagt gaatatgatc cgttaaatta atatagagaa tttcatctaa ggttttgcct
    29701 aatttaattt tacctagatt gataattctc tctgagcaag caacaacttc ttgtggcacc
    29761 gtaataaata actctgtgaa gcgattcata ttgtcactat tttttaaaac aaatgatgtt
    29821 tcgatagcat taagctcaat actatctcca actttttttc caaaggcaat cccttttccc
    29881 atcaataaaa tatctaatcc ttgatggttg gtcgaaatcg ccgcattatg gtttaaaacg
    29941 cgtttaatca acataaaagt cctagtcctt tagtatcaca ataaaaaatg acctatccaa
    30001 aagctcgcta aaaagcactt ttcgaatagg tccctgctca caaaactgtg ataacatcct
    30061 ttaatattct gattgttatg tctctagcct gcttacttga agtaatcaca tctgagaacg
    30121 ctttaatgtt atcatctctt taagattctg tcaagcgttt tcaaaaaatt ctctgaaaga
    30181 gcaactattg ttattcgtat ctattgattt agcaaaaaag agtttctgac aattttaaga
    30241 ttatatgata caataacaat cgattagata aaggagttat catgtcacat catcaacaaa
    30301 ccgtttcaaa acaaacaatt atggcgatta tcgccatagc actcattggt ttttcaggaa
    30361 ttttgtctga aaccagtatg aatgtcacct tcccgacact gatgtcagtc tatcagttac
    30421 ccttaaatag cttgcaatgg atgacgacca tttatttact agcagtggcg attatgatga
    30481 ccacttcggc tacactgaaa aaaaatgtgc gggaaagacc cctctttttt atggccacag
    30541 gtctttttac atttggcacc atcttggccg ttctgaccca gtcctttgcg atcatgttgc
    30601 tagcccgcat ttttcaaggc attggtactg gtctggtaat gcctcagatg tttaatatta
    30661 ttttagagcg tgtcccaatg cataaggtag gtctatttat gggatttgct ggtcttatta
    30721 ttagcttagc acctgctttt gggcctactt atgggggctt tatgattagc cattttagtt
    30781 ggcaatggat ttttatctgt atactccctg taccactgat tgcaggtatt ctagcttatt
    30841 attacctcga agattctcca gtaagcgaaa aagtaccctt tgactggttg gcatttattg
    30901 cactatcgat tagcttaact tctgccttat tagctattac tagtctagaa aacggaagtg
    30961 ttaatttgta ttacttaggg ctttttattc tcagctttgt cctcttcctc tacaagaatc
    31021 tcacagctaa gcaacccttt cttgatattc gcattctcaa aattccctct ctaacctttg
    31081 gcctgattcc cttttttgtc ttccagctga ttaatttagg cataaatttt ctaacgccaa
    31141 actttattgt catggaaaag attgctaata gttctcaagc tggtatggtg ttactacctg
    31201 gtaccttact cggagctcta ctagcacctg cttttggtaa actttatgat caaaaaggag
    31261 caaaactttc gctttattta ggaaatgcct tatttagttt atcattgatt attatgacac
    31321 ttcaaacaag acattttatg cttttaccat tcactctttt atatatttta ttcacgtttg
    31381 ggcgtaacat gggctttaat aatagcttag ccacggctat tcgagaattg cctgccgaga
    31441 aaaatgccga tgccacggcc atttttcaga tgatgcagca atttgctggc gctctaggaa
    31501 ctgctatggc atcactgata gcaaatagtc aaccagaatt cacaagcggt gtccagtctg
    31561 tctaccttct ctttactatt tttgctctac ttgattttat ctttttcttt gctatgtttt
    31621 accatttagg gaaaaaagga cttgcctaag ctgacttact taaaaaccag cctcgttctg
    31681 ttgaacaaga ctggtttttt tcttataaaa taccttctaa aagacctttc ataaagtctt
    31741 ctgagtggaa ttctccaata tcatccactt tttcaccaaa tccgatgaac ttgactggaa
    31801 tgtctaattc ttgacggatg gctaggacta caccaccttt ggccgtgcca tcaattttcg
    31861 ttaaaatcaa acctgttaat ggtgttattt ttgaaaattc cttggcttgg ctaagcgcat
    31921 tttgacctgt tgacgcatct aaggccaaaa gcgtttcatg aggggcatct ggtagcacgc
    31981 gcttaatgat acgacccatt ttttccagct ctgccatgag attttctttg ttttgcaggc
    32041 gaccagccgt gtcaatcagg agaatatcta caccttttgc cacagctttt tccatcccgt
    32101 caaaaacaac agacgctgga tcagcctttt cagggccagt aatgactggc acatctactc
    32161 ggcgtcccca ttcgactagc tgagccacag cccctgctcg gaaggtatct gctgccacca
    32221 acatgacttt tttaccttct tgtttgtaac ggtaagccag cttcccgatt gaagtcgttt
    32281 taccaacccc gttaacacct acaaaaagca taaccgtcaa gccatcttga taattaatgg
    32341 cttcattata acgcccgtct ttttcataga tatctaccaa tttttccaca atcacacgtt
    32401 tcaaggcatc tggttttttc gcattttcca gtttggcttc ataacgcaac tcctctgtca
    32461 aagttgtcgc cacatgtaca ccgacatctg ataagatcag catttcttcc aagtcttcaa
    32521 agaattcttc atccactcgc ctgaaattgg caaagaaact gttcagacga gctgagaagc
    32581 cagtccgcgt ttttttcaag ctacgcttgt atttttcttg atctgtctca ggaatggtat
    32641 cgtgggttgc cttgttttga gaagcttctg ctgaggtaga ggcctgattt tcttgtggaa
    32701 cttcttctgg catcactgga accgttgccg ctgctttttc ttgaaggctt ttttcaagag
    32761 cagccttacg acgatagtag tcttccataa cctgttggct actggattgc tcttttgaag
    32821 tgtctactgc ttcttcattc gccgaatcat ttgaggcatc agcttgagct tgttttgttg
    32881 gaaactgttc cacaactggc tggtcaacaa ggtcttttgg ttctgatgcc gtagattgac
    32941 taagttcact taccttaagg tctgttttgt cggcagcaaa ctcattggta tcttctgatg
    33001 gatgattact attgtcacct gtttcttcct caacctgtgc gtttactgaa gctgcttcgg
    33061 gaccattttc caccgaacct gcgccctctg aagaaacgtc ctcttgttga accacctcaa
    33121 tcttgttttg ctcattggct ttttcagaaa gctcctcttt ctgagttgtt tctgtcaaaa
    33181 gattttcttc taacttttcc tcagctacct tcggggtttc ttttttccca aataaacgat
    33241 caaataatcc cattaactct cctcttctaa aataaatgtc ttcacagctt ctgcgactcc
    33301 agactcatca ttggttaagg tggtcacggc atcggcaacg gctttagctc ctgaaacacc
    33361 attagccata gctactccaa gtcctgccca ttctaacatc gcaaagtcgt tagcttcgtc
    33421 tcccatagcc atgacatgtc tagcgtcaag gccaagatgc tggcaaagca agtttaatcc
    33481 aaaagcttta tcaatgcctt ttggcatgat ttcaaaaata atatctcgtg atttaaaggc
    33541 ttcaaaatcc tcaaataagc ttggggatag ctttataatc tgctgatcca aaaagtctgg
    33601 atcggtgact gtcacaattt tgttataggt aatgtctttt ggtagttccg ctacagatgt
    33661 cacctcaata aaggtcaaca gtgggttagc tagatggtac tgcgaatgcc taccgtcctt
    33721 acttggaatg ctatacacat ccccaccact gataatatct gttggtaagc caaccgcctc
    33781 taaagcttgc tgaatctggc aaacctggtc aaaactgaga gagctcttat ccaaaacctc
    33841 ccctgtattt cgctgaacca aacccccatt aaaggtaata ctgtagtcat cgtggtcaag
    33901 caagtccaac tcttctagca agttaccgat ggcctttaga gggcgacctg tggtaataac
    33961 caccttaacc cctttttctc tagccgctgc taaggctttt ttattggcat ctgtgacaat
    34021 tttttcagtg ttgtagaggg taccgtctaa atcaagcgcc aaaattctaa tattcatgag
    34081 ttacactagt ccttttaaat acgttagtac tgctccgtca ttacagtggc caatgacttg
    34141 gtctgaaatc actttgattt caggtcttgc attttccgta gcaatagccc taccagcaaa
    34201 ctccaacatc tggtaatcat taaaattatc cccaaaagca atcgtttctg ctttcttaat
    34261 gcccaaggct tgacaaagat gctccatacc aaagccctta ttcacctctt ttaagataat
    34321 atcaatggaa tcaaagccgg tggtcactgc agtggcataa gggagggctt gattcaacca
    34381 atcgcttcct tctaagacgg tatggcctgt gaagttggta gaaactttaa aaatggcgtc
    34441 attctccata tcttcaaaac cattaataac cttaacatta gcatagtaat gttttgtttt
    34501 ttgaatgtac tcttctgatg cgccttttaa aatataggct gccttttgcc cagaaaaaac
    34561 catacctgtt tctacatagt gaggattggc taaaaccttt tttgcaactt cggtatactg
    34621 ctctttggtc atcatatctg caaatagaat ctcaccatgg tattgaacca cggaaccatt
    34681 ttctgcaata acagcaatct gatccaaaaa gggctcaaag agctgatcaa tggctaagag
    34741 cgagcggcca ctcgaaaccg caaataaaat gcctttttcg gctaactttg gcaagagcgc
    34801 agctagttgc tcttgattat aagtaccatc ttcagctagg aaggtaccat ccatatctgt
    34861 tgctattagt ttaatcatac aatgtctcct ttttttactc taggggggtg caaacgccat
    34921 ttagggtgtg cactttttaa cgatttaaat aagccccatc atttctgcat tctgttcaat
    34981 ttttcttatt atatcataaa aagcagcttt cattccattc gtaaaaaaca gccagattat
    35041 atttcgataa cctgaccgtt tttgaagtga actgctactt ttttattttt ataaatgacc
    35101 actggatgta tactataaaa gtagacaaaa ctttgtgtgt tacaatctgt tttaaaagac
    35161 acaaaaacga aaggacaacc tatgtcaaca gttaaacgct acgatgaaga attcaaacaa
    35221 tctcttgtca acctttatca aactggaaaa actcagtctg aactctgtaa agactatggg
    35281 gtatccgctt ctgcgcttgc aaaatggatc aaacagtatt ctcaagtcaa actcgaagat
    35341 aattctgtac ttactgccaa gcaaatacaa gagctacaaa aacgtaatgc gcagcttgaa
    35401 gaggagaacc ttatcctaaa aaaagcaagt gccatattca tgcaaaactt aaagtaagac
    35461 tcctcgctgt ctatcggtta cgctttgaac acgacacaac aaccttatgt cgtgttttac
    35521 gtgtcaatcg ctccacttac tataaatttc taaaacataa gccctcaaaa agagaattgg
    35581 ataatcaaat ttatagaaaa caaatacttg agatttatac caaagcaaac aaaagacttg
    35641 gtgtgaagtc tatcaaggtc attcttcaaa gagactacga cacaaaaatc tctgaaggaa
    35701 gaatttaccg tcttatgaag aatatggcgc tccctaaaat ggctaccgtt aagccaaaaa
    35761 cagctcttaa aaggactcaa aaaacgtatc ctcaaaactt actcaaccag aaatttaatc
    35821 ctgacaaacc aaatcaagta tggtctactg acttcaccta tatttctatt ggatataaga
    35881 aatatgtcta tctctgcgca atacttgatc tctattctag aaaatgtatt gcttggaaac
    35941 tgagtcatca tatggatgca aagttagcat gtgacactct agaattagct cttaataaaa
    36001 gaaagattga aggaacactt ctctttcatt ccgaccaagg gtcacaattt aaggccagga
    36061 aattgagaaa aataattgat gacaacacta tcatgcattc tttttctaaa cctggatatc
    36121 cttatgataa tgccgtaact gaagcatttt tcaagtattt aaagcataga caaatcaacc
    36181 gaaaaaagta tcaaaatatc aaacaggttc aattagactg ctttgaatac attgagaatt
    36241 tttataacaa ttacaaccca catacggcta atctaggact aacccctaat cagaaagaag
    36301 aaaattagtt taacgtaata aaataacacg gttttctgtc tacttatttg acattagtcc
    36361 aaaatacatc ctaatggtgt cgtttttttt atttcactag acattcgttc tagtttagga
    36421 tataagaagg tctcaaattt ttttcatgat gtttattcca aacatccaat cacctttcta
    36481 tataactgtt catttagtgg tatagacaaa cagaaatact ccgtttctag tttcatagaa
    36541 gacggagtat tttttagtag agacgtctgg attgatagat agttggtata tagctcatcc
    36601 ctactaggct ttcattatag actatggtgg gtttcgttga caacaatatg tgattattat
    36661 tctaaatgac agtatacatc aactatcaag tatgctttta attttatttt ttaaagctac
    36721 agatgaaaat ctgtattcca tacttccatc taatcgaaca ataatataat gatgtctcga
    36781 atataattca tgttaaaaaa actttgatac ccacttaatt tatttgctaa ttcaagacaa
    36841 ttcttataga ttttcacatc tattttttca actaatatca ttattctatc ttcaatttca
    36901 tactcaatct cttgtgataa aacagtggtt cctattccca tgcaaactcc taatacgttt
    36961 actttattaa atttagaaac catatcatca attctaccac catcagcaat atcaaatatg
    37021 tcacctgact tagttcgtat gaagatttta tagttcatac ttgaataatg tcctgttcca
    37081 tataaattag ataatgaaaa gtaaatgcaa tctgctggta aaaagttttt tacatactcg
    37141 tacaagacta aaacttttat aaattcctgt ttcaccagtt tgttacttat ttttgaaata
    37201 agactaatta agagttccat atttattttg tcttt
//
LOCUS       DATWEK010000016        33454 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.016, whole genome shotgun sequence.
ACCESSION   DATWEK010000016 DATWEK010000000
VERSION     DATWEK010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33454
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.016"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            168..644
                     /locus_tag="VCR92_000969"
     CDS             168..644
                     /locus_tag="VCR92_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEP4268050.1"
                     /translation="MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGE
                     TPDECARREILEETHLTVTEMAFKGIITFPEFTPGHDWYTYVFKVTGFEGDLISDEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY"
     gene            702..1883
                     /locus_tag="VCR92_000970"
     CDS             702..1883
                     /locus_tag="VCR92_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEP4268051.1"
                     /translation="MPLIPDKSRTDSLFYKWFLNNQATMALVITLLAFLTIFVFTKIS
                     FLFMPVISFFAVIMLPLVISTILYYLTKPLVDLINHLGPNRTTSIFIVFGLITLLFVW
                     AISGFVPMVQTQLTSFIEDLPKYVGKVNEEANKLLENEWLVSYKPQLQDMLTHTSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIISPFILFYFLRDSSHMKNGLVNVLPLKL
                     RVPMVRVLGDINKQLSGYVQGQVTVAIVVGFMFSIMFSLVGLKYAITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMAMVQGPFMLVKVLVIFMIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPIYASVKVVIKELFDWYKKVSGLYDEEVLVIEEVKDHV
                     K"
     gene            1873..3120
                     /locus_tag="VCR92_000971"
     CDS             1873..3120
                     /locus_tag="VCR92_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEP4268052.1"
                     /translation="MLNSEKMIASLDQQDLAHAEKYFQKALKEDDADSLIALGEYLES
                     IGFLPHAKRIYLQLADDYPELNINLAQIAAEDDAIEEAFLYLDKVSKDSPNYLSALLV
                     MADLYDMEGLTEVAREKLLQAVSISPEPLVIFGLAEIDMSLQYFKEAIDYYAQLDNRQ
                     ILELTGISTYQRIGRAYASLGKFEAAIEFLEKAVAIEYEDETVFELATLLYDQENYQK
                     ANLYFKQLETINPDYPGYEYGYALSLHEEHKTSEALRLVQQGLRKNAFDSQLLLLASQ
                     LSYELHDRQNAENYLLQAKEVAVDDEEILMRLVTLYFDAERFEEVIALNRETIDNVLT
                     KWTIAKAYHALEQEEVALALYNEISADLAENPEFLQDYAYLLREFGQFHKAIQMATAY
                     LRQVPDDVNMQDFLDHIKHQQSE"
     gene            complement(3179..4831)
                     /gene="fbp54"
                     /locus_tag="VCR92_000972"
     CDS             complement(3179..4831)
                     /gene="fbp54"
                     /locus_tag="VCR92_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein Fbp54"
                     /protein_id="HEP4268053.1"
                     /translation="MSFDGFFLHHLTNELKENLLYGRIQKVNQPFERELVLTIRNHRK
                     NYKLLLSAHPVFGRVQITQADFQNPQVPNTFTMIMRKYLQGAVIEQLEQIDNDRIIEI
                     KVSNKNEIGDAIQATLIIEIMGKHSNIILVDRAENKIIESIKHVGFSQNSYRTILPGS
                     TYIEPPKTAAVNPFTITDVPLFEILQTQELTVKSLQQHFQGLGRDTAKELAELLTTDK
                     LKRFREFFARPTQANLTTASFAPVLFSDSHATFETLSEMLDHFYQDKAERDRINQQAS
                     DLIHRVQTELDKNRNKLSKQEAELLATENAELFRQKGELLTTYLSLVPNNQDSVILDN
                     YYTGEKIEIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTKQSITYFESVDYN
                     LSQASIDDIEDIREELYQAGFLKSRQRDKRHKRKKPEQYLASDGKTILMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLDPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPDQAKILSMKLS"
     gene            5185..6183
                     /locus_tag="VCR92_000973"
     CDS             5185..6183
                     /locus_tag="VCR92_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEP4268054.1"
                     /translation="MKNKSLIATLLVLTVIVIGSLLSKGVSKENRDLANRQNITIGIL
                     QFVTHEALDDIKRGIEDQLKKQMPQKQNVVIKVMNAEGDQSKIQTMSRQLVQSGSDIV
                     IGIATPAAQGLAAASKDIPVVMSAVSDPVGSRLVMQLDQPEANVTGLSNKVPVKQTID
                     LMKNLTPHVKTVGILYASNEDNSLSQVKEFRRLARKKGYQVISYAVPSTNEVPATMSV
                     MLGKVDAVFIPQDNTIASAFSSVMTTSKAAKIPVYTSVDRMVEKGGLAAISQNQYDLG
                     VQTANQVLKLIKGKRVVDVPVKVVDIGQPLINKNVAAELGIAINREDFPSASFIEN"
     gene            6528..7397
                     /locus_tag="VCR92_000974"
     CDS             6528..7397
                     /locus_tag="VCR92_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4268055.1"
                     /translation="MIISSVSQGLIWGVLGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTAISLGWNPFLSTLLGMLSGALAGFLTGLLYTKGKMPTLLAGILVMTSCNSIMLMVM
                     GRANLGLHDHKRIQDCLPFSIDLNSLLTGLITVVIVISVLIYFLYTNLGQAYIATGDN
                     KDMAKSFGINTDWMEVMGLVVSNSLIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVIGSILYQFLISVVITLGFNTSYLKLISALVLALCLMIPV
                     VKERYFKGVRLTR"
     gene            7394..8152
                     /locus_tag="VCR92_000975"
     CDS             7394..8152
                     /locus_tag="VCR92_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4268056.1"
                     /translation="MTKIIELINATVDVDNGFEDAKTILDNVTLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLSLTRGQIRILGQDVTHWPAEKRALYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGEKRSLASRKITEHLASFEDLVKRTGNGLEKHLETPAGLLSGGQRQAL
                     SLLMATLKKPALLLLDEHTAALDPKTSQSLMQLTDEFVTKDGLTALMITHHMEDALTY
                     GNRLIVMKDGNIIKDLNQMEKEQLTITDYYQLFD"
     gene            8356..10017
                     /locus_tag="VCR92_000976"
     CDS             8356..10017
                     /locus_tag="VCR92_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEP4268057.1"
                     /translation="MTDIKMIALGGVREYGKNFYLVEINDSMFILDAGLKYPENEQLG
                     VDLVIPNLDYVIENKGKVQGIFLSHGHADAIGALPYLLAEVSAPVFGSELTIELAKLF
                     VKSNNSTKKFNNFHVVDSDTEIEFKDGLVSFFRTTHSIPESMGIVIGTDKGNIVYTGD
                     FKFDQAAREGYQTDLLRLAEIGKEGVLALLSDSVNATSNDQIASESEVGEEMDSVISD
                     ADGRVIVAAVASNLVRIQQVFDSATAHGRRVVLTGTDAENIVRTALRLEKLMITDERL
                     LIKPKDMSKFEDHELIILEAGRMGEPINSLQKMAAGRHRYVQIKEGDLVYIVTTPSTA
                     KEAMVARVENLIYKAGGSVKLITQNLRVSGHANGRDLQLLMNLLKPQYLFPVQGEYRD
                     LAAHAKLAEEVGIFPENIHILKRGDIMVLNDEGFLHEGGVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSHDILRESAELVNTT
                     VGNYLKKDTFDWGELKGNVRDDLSKFLFEQTKRRPAILPVVMEVR"
     gene            10150..10935
                     /locus_tag="VCR92_000977"
     CDS             10150..10935
                     /locus_tag="VCR92_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEP4268058.1"
                     /translation="MASIAIEYHSVVLGMERKVNVIYPDQSEIPKKDQGDKDIPVLYL
                     LHGMGGNENSWQKRTAIERLLRHTNLIVVMPSTDLGWYTDTAYGLNYYRALSQELPQV
                     LAAFFPNMTQKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALDFSPETLLEGN
                     LGELAYWQGVFGQFDDPDLDKHYLKNMVAESDGKTKFYAWCGYEDFLFATNEKAIADF
                     QAQGLDIDYHKGHGKHEWYYWNQQLEVLLEWLPINYQKEERLS"
     gene            10965..11291
                     /locus_tag="VCR92_000978"
     CDS             10965..11291
                     /locus_tag="VCR92_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268059.1"
                     /translation="MKQLLAIILWLPKLIVKMFWHLIKGFLQTILLVTIIIIGLMYYS
                     NHSDSVLANKISIVTEQVVQIFDILTQKPSAKTRHGSGNSHSTFLVSAKEGNQRLKKS
                     SISFGN"
     gene            11337..13244
                     /locus_tag="VCR92_000979"
     CDS             11337..13244
                     /locus_tag="VCR92_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEP4268060.1"
                     /translation="MIILQGNKLERSFSGDVLFQNISLQVDERDRIALVGPNGAGKST
                     LLKLLVGEETPTSGEVNTKKDLTLSYLAQNSRFESDKTIYEEMLKVFEALRQDEKRLR
                     QMEMDMATVSGQDLTRLMMDYDLLAERFRQQGGFTYEAEIKAILNGFKFDESMWQMTI
                     AELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLENYLANYQGALIIVSHD
                     RYFLDKVATVTLDLTPHGLDRYVGNYSRFMTLKAEKLVAEEKQFDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKIERLDKPTSARKSAHMTFQADKPSGNVVLTVEKAAI
                     GYNQHVLSEPINLDVHKLDAIAIVGPNGIGKSTLIKSVIGQIPFIKGEVKYGANVEIG
                     YYDQTQSHLTSSNTVLEELWQDFSTTPEVDIRNRLGAFLFSGDDVKKSVAMLSGGEKA
                     RLLLAKLSMENNNFLVLDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRLAT
                     KVLEITENGSTLYLGDYDYYLEKKAELEELARLAAGETVEETKEASATDYQLQKANQK
                     ERRRLTRRYEEIEARLETIEERIGAIQEDMHASNDTAQLIAWQKEWDQLDQEQETLME
                     EWETIAEQIES"
     gene            13530..14498
                     /locus_tag="VCR92_000980"
     CDS             13530..14498
                     /locus_tag="VCR92_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEP4268061.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLSYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MGKAVEHVRGGNGPAIVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLT
                     SEGIATDDELDAIQAQVKKEVDDAYEFAQNSPDPELSVAFEDVWVD"
     gene            14557..15555
                     /locus_tag="VCR92_000981"
     CDS             14557..15555
                     /locus_tag="VCR92_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEP4268062.1"
                     /translation="MSETKLMALREAVNLAMTEEMRKDENIFLMGEDVGVYGGDFGTS
                     VGMIEEFGPKRVKDTPISEAAISGAAIGAAITGLRPIVDVTFMDFLTIMMDAIVNNGA
                     KNNYMFGGGLITPVTFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGNANDAKGL
                     LKSAIRDNNIVLFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDLTIVSYGRMLE
                     RVLQAAEEVAADGINVEVVDPRTLIPLDKELIIESVKKTGKLMLVNDAYKTGGFIGEI
                     ATMITESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVEKIKAAIVKMANKGN"
     gene            15740..17149
                     /locus_tag="VCR92_000982"
     CDS             15740..17149
                     /locus_tag="VCR92_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEP4268063.1"
                     /translation="MAFEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKIVRPAGDTVPVTEVIGYIGAEGESVDTIASSEKTTEIPVPASAD
                     AGPAVAPKENVASPAPQVAATAIPQGNGGKVRATPAARKAAAEMGIDLGQVPGTGPKG
                     RVHKADVENFKGAQPKASPLARKIAADKGIDLATVSGTGFNGKVMKEDIMAILEAAKP
                     AEAKAPAAKEEKVVDLAEGVEHKPMSAMRKAISKGMTNSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGMAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLIVPVIHGADKMSLSDFVLASKDVIKKAQTGKLKAAEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGVGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            17480..19243
                     /gene="lpdA"
                     /locus_tag="VCR92_000983"
     CDS             17480..19243
                     /gene="lpdA"
                     /locus_tag="VCR92_000983"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEP4268064.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAEGESVEVSSPAASDVNVARTTEDL
                     EAAGLEVPKAPAQAASAAPKAALADDEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVEK
                     SEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTVV
                     KTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGSQTIKGRNVILATGSKVSRINIPG
                     IDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVDVTVIEMADRIIPAM
                     DKEVSLELQKILSKKGMKIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRVP
                     QMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENAI
                     HGNTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASNE
                     AHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMESELTVDELLLSIHGHPTFSE
                     VMYEAFADVLGEAIHNPPKRK"
     gene            complement(19916..22333)
                     /gene="hylA"
                     /locus_tag="VCR92_000984"
     CDS             complement(19916..22333)
                     /gene="hylA"
                     /locus_tag="VCR92_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEP4268065.1"
                     /translation="MNTYFCTHHKQLLLYSNLFLSFAMMGQGTAIYADTLTSNSEPNN
                     TYFQTQMLTTTDSEKKVVQPQQKDYYTELLDQWNSIIAGNDAYDKTNPDMVTFHNKAE
                     KDAQNIIKSYQGPDHENRTYLWEHAKDYSASANITKTYRNIEKIAKQITNPESCYYQD
                     SKAIAIVKDGMAFMYEHAYNLDRENHQTTGKENKENWWVYEIGTPRAINNTLSLMYLY
                     FTQEEILKYTAPIEKFVPDPTRFRVRAANFSPFEANSGNLIDMGRVKLISGILRKDDL
                     EISDTIKAIEKVFTLVDEGNGFYQDGSLIDHVVTNAQSPLYKKGIAYTGAYGNVLIDG
                     LSQLIPIIQKTKSSIEADKMATIYHWINHSFFPIIVRGEMMDMTRGRSISRFNAQSHV
                     AGIEALRAILRIADMSEEPHRLALKTRIKTLVTQGNAFYNVYDNLKTYHDIKLMKELL
                     SDTSVPVQKLDSYVASFNSMDKLALYNNKHDFAFGLSMFSNRTQNYEAMNNENLHGWF
                     TSDGMFYLYNNDLGHYSENYWATVNPYRLPGTTETEQKPLEGTPENIKTNYQQVGMTS
                     LSDDAFVASKKLNNTSALAAMTFTNWNKSLTLNKGWFILGNKIIFVGSNIKNQSSHKA
                     YTTIEQRKENQKHPYHAYVNNQPVDLNNQLVDFTNTKSIFLESDDSAQNIGYYFFKPT
                     TLSISKALQTGKWQNIKADDKSPEAIKEVSNTFITIMQNHTQDGDRYAYMMLPNMTRQ
                     EFETYISKLDIDLLENNDKLAAVYDHDSQQMHVIHYEKKATMFSNHNLSHQGFYSFPH
                     PVKQNQQ"
     gene            22566..23555
                     /locus_tag="VCR92_000985"
     CDS             22566..23555
                     /locus_tag="VCR92_000985"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEP4268066.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVEEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIDEHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTAEGAFDFKTFS
                     QPVIATLADLGVTANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKITVEEFSDKILTKMKETYPDMTEYVLS
                     EDELAKIEQSAKEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSIIKNLKIY
                     GDFFGIKDVQDIENLLIGCKYEYRDVFECLKTIDTTQYFSRMTVEEVAKAIVS"
     gene            complement(23668..24459)
                     /locus_tag="VCR92_000986"
     CDS             complement(23668..24459)
                     /locus_tag="VCR92_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEP4268067.1"
                     /translation="MTYTSLKSPENTDYLYDLNIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGARVTVDIVSINDTFEQDDYDIVFFGGGQDYEQSIVAKDLPSKKAALADYIANNK
                     VVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKIHNDEFNETYY
                     GFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVNLA
                     YRLVTTSLKKKYGSAISLPSYDDILKQEITEEYADLKSKASFNKV"
     gene            complement(24459..25802)
                     /locus_tag="VCR92_000987"
     CDS             complement(24459..25802)
                     /locus_tag="VCR92_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEP4268068.1"
                     /translation="MKMKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACNKDILKDL
                     SKDYDIVVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKS
                     GRQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGARNAPK
                     ATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEGILCPKCEHILQYRLNT
                     YANLGDFICLNCGFKRPQLDYRLTELTAITHQSSEFVIDGQNYKINVGGLYNIYNALA
                     AVSVAEFFGVSPEKIKAGFNKSKAVFGRQETFTIGDKSCTLILIKNPVGASQALEMIQ
                     LADYPFSLSVLLNANYADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVT
                     GFDDTKIKQAEKLEQIMEAIEKQESKHAYILATYTAMLEFRSLLADRHVVEKEMN"
     gene            25909..26760
                     /locus_tag="VCR92_000988"
     CDS             25909..26760
                     /locus_tag="VCR92_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEP4268069.1"
                     /translation="MNNLSSIDIKFLLSLFADPWLLAVHLLDILIVAYLIYRFIKALT
                     GTKIMSLVQGVIFFLVLRFIAEWIGFTTITYLMNQVITYGVIAGVVIFTPEIRAGLEK
                     FGRSTQVFLQKQYVSSESALVDALIKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVGQNKIVAACAYLPLSESKAISKEFGTRHRAAI
                     GLSENSDALTIIVSEETGAISVTRKGQFLHDLSTDEFETVLRTYLMSDSNVSLPWYKK
                     ILGGKSK"
     gene            26757..27713
                     /locus_tag="VCR92_000989"
     CDS             26757..27713
                     /locus_tag="VCR92_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEP4268070.1"
                     /translation="MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIET
                     YTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLT
                     HSHPGTVNVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEI
                     SKIETGVNKVEVTSDESTIALIDHVVAKLPDDQVLDRNYSSRVTLQAVSADGTILASA
                     IDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDID
                     EIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK"
     gene            27767..29122
                     /locus_tag="VCR92_000990"
     CDS             27767..29122
                     /locus_tag="VCR92_000990"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEP4268071.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKV
                     FVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKY
                     EKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGS
                     THPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLA
                     HNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAI
                     ANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCD
                     N"
     gene            29246..29887
                     /locus_tag="VCR92_000991"
     CDS             29246..29887
                     /locus_tag="VCR92_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268072.1"
                     /translation="MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTPKQDI
                     QKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAV
                     NEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLAD
                     MQENLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSRP"
     gene            29950..31080
                     /locus_tag="VCR92_000992"
     CDS             29950..31080
                     /locus_tag="VCR92_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEP4268073.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQE
                     FDSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPE
                     KIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIY
                     ALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEM
                     FEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQN
                     RVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGVSFEE
                     RYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD"
     gene            31090..31842
                     /locus_tag="VCR92_000993"
     CDS             31090..31842
                     /locus_tag="VCR92_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEP4268074.1"
                     /translation="MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGR
                     SNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGG
                     LLVDILAYFALLNPDTRKVATIPEDLVAPFKTDFVKKPHRVPKMPLLEQSIDRDYYVR
                     YFDIDMNGHVNNSKYLDWMYDVLGCEFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQ
                     LTSYHQITSDGQLNAQAMIEWRAIKQTESETD"
     gene            31842..32606
                     /locus_tag="VCR92_000994"
     CDS             31842..32606
                     /locus_tag="VCR92_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEP4268075.1"
                     /translation="MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNN
                     TTRTPEMVQSMLANQFHVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     AAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQN
                     DIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL"
     gene            32606..33238
                     /locus_tag="VCR92_000995"
     CDS             32606..33238
                     /locus_tag="VCR92_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEP4268076.1"
                     /translation="MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVF
                     MSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLL
                     YPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHQVLFVGDS
                     SWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE"
BASE COUNT        10299 a         5843 c         7041 g        10271 t
ORIGIN      
        1 gatagtttaa attgatgttt ttcattgtag gctcttatct acactttttt aaggcatctt
       61 tagaaggttt tgagcgtgac taagtattca cactttgact cataaaatga tagcatattt
      121 tctagagatt ggtataatag aaacaaagat ggaaaggaaa gagatagatg actcaattag
      181 caaccatttg ttacattgat aatggcgatt ctttgctatt attacaccgc aataaaaaag
      241 aaaatgatgt ccacaaaggc aagtggattt cagttggggg taagctcgag gctggtgaga
      301 ccccagatga gtgtgcccgt cgtgagattt tagaggaaac ccatttgact gttacagaga
      361 tggcctttaa aggaatcatt acttttccag aatttacccc tggtcatgac tggtatacct
      421 atgtttttaa agtaacagga tttgaaggag acctcatttc cgatgaagag tcacgagaag
      481 gaaccttgga atgggtacct tacgatcaag tgttggaaaa gccaacttgg gaaggtgatt
      541 atgacatttt taaatggatt ttagaagacc gtcctttttt ctctgccaaa tttacctatg
      601 accaaaacaa ccaactcatg gataaatctg tgacctttta ttgatttacc caggttacca
      661 gtaaaactta tcattttccc aaagaaagga accctatctt aatgccctta atacctgaca
      721 agtctagaac agatagctta ttttacaaat ggtttttaaa taatcaagct accatggctt
      781 tagtaataac acttttagcc tttttaacga tttttgtttt tactaaaatc tcttttttat
      841 ttatgccagt gatttctttt tttgcggtca tcatgttgcc cttggttatt tcgaccattc
      901 tgtattatct gaccaaaccc ttagttgacc ttattaatca cttgggcccg aatcgtacca
      961 cctctatttt tattgttttt ggtttgatta ccttactttt tgtctgggcg atttcaggct
     1021 ttgttcccat ggtacagacc caacttacca gttttattga ggatctgccc aaatatgtgg
     1081 gcaaggtcaa tgaagaagcc aataaacttc ttgaaaatga atggttagtc agctacaagc
     1141 cccaactcca agacatgctt acccatacaa gtcaaaaggc tttggattac gcgcaaagtt
     1201 tttcaaaaaa tgctattgac tgggctggta attttgctgg tgccattgct cggattaccg
     1261 tggctattat tatttcgccc tttattctct tttatttttt acgagacagt agccacatga
     1321 aaaatggcct tgtgaatgtc ttacctctca aattacgggt gcctatggtt cgagtcttgg
     1381 gagatattaa caagcaatta tcaggctatg tccaagggca ggttacggtt gcaattgttg
     1441 tcggctttat gttttctatc atgtttagtc ttgtgggact gaaatatgcc atcacttttg
     1501 ggattattgc tggctttctt aacatgatac cttacttagg aagtttcctt gccatgatac
     1561 ctgttgtgat tatggctatg gtacaaggcc catttatgtt ggttaaggtg cttgttatct
     1621 ttatgattga gcaaaccatc gaaggccgtt ttgtggcacc gcttgttctt ggaaataagc
     1681 tgagcattca tccgattacg atcatgttct tattgttgac tgcaggatca atgtttggcg
     1741 tttggggtgt cttcttagtc atcccaatct acgcttctgt caaagttgtg attaaagaat
     1801 tatttgactg gtacaaaaaa gttagcggtt tgtatgacga agaagtattg gtgattgagg
     1861 aggttaagga ccatgttaaa tagtgaaaaa atgattgctt ccttggatca gcaagaccta
     1921 gcgcacgctg aaaaatattt ccaaaaagct ttaaaagaag atgatgcaga tagtttaatc
     1981 gccttaggag aatacttaga aagtataggt tttttgccac atgccaagcg tatttatttg
     2041 cagttagctg atgattaccc agaactcaat ataaatttag ctcagattgc agcagaagac
     2101 gacgccattg aagaagcttt cttgtatttg gataaggttt caaaagatag ccccaattat
     2161 ttgtcagctc tcttagtaat ggctgacctc tatgacatgg aaggactgac agaggtggcg
     2221 cgtgaaaaat tgcttcaagc agtgagcatc agcccagagc cattggtcat ttttggtttg
     2281 gcagaaattg acatgtcctt gcagtatttt aaagaagcta ttgattacta tgcacagtta
     2341 gacaatcgtc aaatccttga attgacaggt atttccactt atcaacgcat tggacgagcc
     2401 tatgctagct tagggaaatt tgaggcagcc atcgaattct tggaaaaggc cgtggccatt
     2461 gaatacgaag atgaaactgt ttttgaattg gcgaccctct tgtatgacca agaaaattat
     2521 caaaaagcta atctttactt taaacagttg gaaaccatca atccagatta tccaggttat
     2581 gaatatggtt atgctttgag tcttcatgaa gagcataaga cgtcagaagc tttgcgcttg
     2641 gttcaacagg gcctacgtaa aaatgcattt gacagtcaat tattattact agcatcgcag
     2701 ctttcttatg aattacacga taggcagaat gctgaaaatt acctgcttca agcaaaggaa
     2761 gtagctgttg atgacgaaga gattctcatg cgtttagtga ccctttattt tgatgccgag
     2821 cgttttgagg aggttattgc tcttaatcgt gagacgattg ataatgtctt aaccaaatgg
     2881 accattgcaa aggcttacca cgccttggaa caagaagaag ttgccttggc tctttataat
     2941 gagatttcgg ctgatttggc agaaaatccg gagtttttac aggattatgc ctatttatta
     3001 agggagtttg gccagtttca caaggctatc caaatggcta ccgcttacct cagacaagtg
     3061 cctgatgatg tgaatatgca agactttctt gaccatatca agcaccaaca atcagaataa
     3121 aaaaacagtt ctcctagggg aaataacttt cctaggagag ctgtttttta gttgcttatc
     3181 aggataattt catagagaga attttggctt ggtcaggagt aacccgtaaa gttttttgac
     3241 cagtataagt cacaaatcct ggcttggcgc cactaggttt gtgtaatttt ttagcttcaa
     3301 tcatatcgac ctgaacgaga tttgataacc tagctttcga ataataagca gctagttcgg
     3361 cagcatcagt tttaacctcg tcacttgggt caagattgtc tttgatgatg acatgacttc
     3421 cagggatatc cttagcatgg aaccagagtt ctcctttttt agccatttta aaggtgagtt
     3481 cttcattttg caagttattg cgtcccacca tgagaatggt ttttccatct gaagccaggt
     3541 actgctcagg ctttttacgt ttatggcgtt tgtctctttg gcgacttttc aaaaagccag
     3601 cctgatataa ttcttcgcga atatcttcga tgtcgtcgat acttgcttga gataaattgt
     3661 agtccacgct ctcaaagtaa gtaatacttt gcttggtatc ggcaatcaat ccagataagt
     3721 gtttgacagc ttcttttagc ttttggtatt ttttaaaata acgttgagca ttttgatttg
     3781 gtgtcagagc cttgtctaag gcaatctcaa ttttttcccc tgtataataa ttgtctaaaa
     3841 tcacagagtc ttggttgttt gggaccagac tgaggtaggt ggtcaataat tctccttttt
     3901 gacggaataa ttcagcattt tcagtggcta gcagctcagc ttcttgctta cttagcttgt
     3961 tacgattttt gtccagttca gtttgcacac ggtgaatcaa atcactggct tgctgattga
     4021 tacggtcacg ctcagcctta tcttgataaa agtgatcaag catctctgat aaagtctcaa
     4081 acgtcgcatg gctatctgag aaaagaacag gcgcaaaaga agctgtggtc agatttgcct
     4141 gagtaggtct agcaaaaaac tcacggaacc gttttaattt gtctgtggtc agaagctcgg
     4201 ccaactcttt tgcggtgtct cgccccaaac cttgaaaatg ctgttgcaag cttttaactg
     4261 ttagttcttg tgtttggagg atttcaaata gaggaacatc tgtaattgta aaaggattaa
     4321 cagcagctgt tttagggggc tcaatgtagg tagagccagg taaaatggtg cggtaagagt
     4381 tttgtgaaaa gccaacatgt ttaatggatt cgatgatttt attttctgca cggtccacca
     4441 agatgatatt gctgtgcttc cccatgattt caatgattag ggttgcctga atagcatctc
     4501 cgatttcatt tttattagat accttgattt cgataatgcg gtcattatca atctgttcta
     4561 actgctcaat gactgcaccc tggaggtatt tacgcataat catggtaaag gtattaggta
     4621 cctgaggatt ttgaaagtct gcttgggtga tttgtaccct tccaaaaaca ggatgggcag
     4681 acaatagcaa tttataattc ttgcgatggt tacgaatggt taagacaagt tcccgttcaa
     4741 agggttgatt gaccttttgg atacgaccgt aaagcaagtt ctcttttaat tcgttggtta
     4801 aatggtgtaa gaaaaagccg tcaaaagaca tggtttctcc tttctgaatt ctaatctctt
     4861 cattatacca caaatacttg actaaaaata tggacgaaag agcttgcaat ttttttgatt
     4921 taggttataa tgttaaaaaa acgagaaagg aagtcaatga tggtaaaaac acaacactta
     4981 gtaaattggc aaggctggca tagataagtt gtgtttatga attggcatag atacgacttt
     5041 tagagtactt ctaaaaagat atctatgcgc tgacattgga tttcacaagg gcgcctagta
     5101 atcattacta agtgcttttt cttttgagaa gtattctcat catcaacgtt ttaaagagat
     5161 tgacatgaaa tgtgaggaat tcagatgaaa aacaagagtt taatagctac cctccttgtt
     5221 ttaactgtaa tagtgatagg ctctctatta tcaaaaggag tatcaaagga aaaccgtgat
     5281 ttggctaacc gacaaaacat tacaattggt atcttacaat tcgttactca tgaggctctt
     5341 gatgatatta agcgaggtat tgaagatcaa ctcaaaaagc agatgcctca aaaacaaaat
     5401 gtagtgatta aggttatgaa tgctgagggg gatcagagta aaatccaaac aatgagtagg
     5461 caattagtgc aatcaggaag tgatatcgtg attggtatcg caaccccggc ggcgcaaggc
     5521 ttagcagctg ccagcaagga tatcccagtt gtcatgtcag cagtatctga tccagtagga
     5581 tctagattag tgatgcaatt ggatcaacct gaagctaatg taactggtct atctaataaa
     5641 gtgcctgtta aacagacaat tgatttaatg aaaaatctga caccacatgt caaaacagtt
     5701 ggaattttat atgcaagtaa tgaggataat tccttatctc aagttaaaga gtttaggcgg
     5761 ttagctcgca aaaagggcta tcaagttatt tcatacgcgg ttccttctac taacgaagtt
     5821 cctgccacga tgtcagttat gttaggtaaa gtagacgcgg tatttatccc ccaagacaat
     5881 actatagcaa gtgcattttc atcagtcatg acaaccagta aggctgcaaa gattcctgtc
     5941 tacactagcg ttgatcgaat ggttgaaaaa ggtggtttgg cagccatttc tcaaaatcag
     6001 tacgatttgg gagttcaaac agctaatcag gtgttaaaat taatcaaagg aaagcgtgtt
     6061 gtagatgttc ctgtcaaagt tgtggatatt ggtcaaccgc taattaataa gaatgtagca
     6121 gcagaattag gtattgctat taacagggaa gattttcctt cagcttcttt tattgagaat
     6181 taatacaatg acatgtgata taaaaggtca agaaaaaacc ataaaaaaca ccctcactga
     6241 gatgaatttg gatgccaagt cagacaatcg tcttgaggat gtaagggtta tttttatcat
     6301 ttttagtttt aaaatgctct atttcagaca cgtaaaaaat cttgcctttt gagtaagttt
     6361 aaacatgatt ctcgattttt ttgttttctg tcttagtttc gttaaagtga ttggaaaaaa
     6421 gactaagcca cggtgctgaa ctaagtataa aacaaatcta aaaattaatg taaagaaagg
     6481 gtttatactg gcgagagtta cccgctaata taaatatgag gaaaaatatg attatttcat
     6541 cagtttcaca aggccttata tggggagttt taggattagg aatctacctg acctttagga
     6601 ttttaaactt ccctgacatg actacagaag gttcttttcc tttaggagga gctgttgcgg
     6661 tcaccgctat tagcttaggg tggaatccat ttctatcaac cttacttggt atgttatcag
     6721 gtgctttagc aggtttttta acagggctgt tatatacgaa aggaaaaatg ccaacacttt
     6781 tagctggaat tttggtgatg acgtcatgta actccattat gctaatggta atgggaagag
     6841 caaacttggg tttacatgat cataaacgta ttcaggattg tttacctttt tcaattgatt
     6901 taaatagcct tttaacaggt ctgataactg ttgtgattgt tattagcgtt ttgatctatt
     6961 tcctttacac taatctaggt caagcttata tcgctacggg agacaataaa gatatggcta
     7021 agagttttgg tattaacacg gattggatgg aagttatggg acttgtggtt tctaatagtt
     7081 taatagcttt atcaggtgct ctagtgagcc aacaagatgg ctatgcagat gtctcaaaag
     7141 ggattggagt tattgttatt ggtttggcga gcataattgt tggtgaagta ctatactcaa
     7201 ctggactgac tcttttagaa cgtttgattg ctattgtaat aggctcgatt ctttatcaat
     7261 ttttaatttc agtagttatt acgctaggtt ttaatacaag ttatttgaaa ttaattagtg
     7321 ctcttgtttt agcactgtgc ctcatgatac cagtggtaaa agagcgctac tttaagggag
     7381 tgaggttaac acgatgacaa aaattattga attgatcaat gcaacagttg acgtagataa
     7441 tggttttgaa gatgctaaaa caatactgga caatgtgaca ctaactatct atgaacatga
     7501 ttttttaact attttaggag gaaatggagc tggaaaatca acccttttta atgtaattgc
     7561 aggaacgcta agtttgacac gggggcaaat taggattctt ggtcaggatg tgacgcattg
     7621 gccggcagaa aaaagagctc tttacctatc gcgagtcttt caagatccca aaatgggaac
     7681 agcccctcgg atgacagtgg ctgaaaatct cttaatcgca cgtcaaagag gagaaaaacg
     7741 ctccttggct tctcgaaaaa taacagagca cttagctagt tttgaggatt tggttaaacg
     7801 aacaggaaat ggcctagaaa agcatttaga aacaccagca ggtcttttgt ctggtggaca
     7861 aagacaggct ttaagtttat taatggcaac gttgaaaaag ccagctctct tattattaga
     7921 tgaacatacg gctgcccttg accctaagac gagtcaatct ttaatgcaat tgacagatga
     7981 gtttgtgaca aaagatggct taacagcttt gatgattacc caccatatgg aagatgcatt
     8041 aacttatggg aatcgtctga ttgtaatgaa agatggaaac attattaaag atttaaatca
     8101 aatggaaaaa gaacaactga cgattactga ctattaccaa ctatttgact aatcaacgat
     8161 ctaaatcatt gactaataat aagtcagtga ttttttgatt tccatactga aaataatctg
     8221 aaagtatcaa ggctatttag agaaaaaacg cctcaaatat gatatactat agaagatagt
     8281 agcatagcta cataacagta attcgactta cgttgtaagg accgtttgta ataataaaat
     8341 atttaaagga gtatcatgac tgatattaaa atgattgcct tgggaggggt ccgtgaatac
     8401 ggaaaaaact tctatttggt agaaattaac gattctatgt ttattttaga cgcagggctc
     8461 aagtaccctg aaaatgagca acttggggta gatttagtca tccccaattt agattatgta
     8521 attgaaaaca aaggtaaagt acaagggatt ttcttgagtc atggccatgc tgacgccatt
     8581 ggagcccttc cttatttgtt agctgaagta tcagctcctg tatttggatc tgaattgact
     8641 attgaattag ccaagctatt tgtgaaaagt aataacagca ctaagaaatt taataatttt
     8701 catgtggtag acagtgatac tgaaattgaa tttaaagatg gcctagtttc gttctttaga
     8761 acaacgcatt caatcccaga aagtatgggt attgttattg gaacagataa aggaaacatt
     8821 gtttataccg gtgacttcaa atttgatcaa gcagcaagag aaggttatca gacggatttg
     8881 ctacgtttag ctgagattgg gaaagaaggg gttctagctc ttttatcaga ttcagtcaat
     8941 gcgacaagca acgatcagat tgccagcgaa tctgaagttg gtgaagaaat ggacagtgtt
     9001 atctctgatg ctgatggccg tgtcattgta gctgcagtag cctcaaatct tgttcggatt
     9061 cagcaagtat ttgattccgc cactgcccat gggcgtcgtg ttgttttaac cggaacagat
     9121 gcagaaaata ttgtcagaac agctttacgt ctagaaaaat taatgattac ggatgagcgt
     9181 cttttaatta aacctaagga tatgtctaaa ttcgaagacc atgaattaat catccttgaa
     9241 gctggtcgta tgggtgagcc aattaatagc ttacaaaaaa tggcagcggg acgtcaccgt
     9301 tatgttcaaa tcaaagaagg agaccttgtt tatattgtaa ctacaccaag tacggctaaa
     9361 gaagctatgg tggcgcgtgt agaaaacttg atttacaagg ccggtggttc tgttaaatta
     9421 atcactcaaa acttacgcgt gtcaggccat gctaatgggc gtgatttgca actattgatg
     9481 aatttgttaa aaccccagta tctttttcca gtgcaaggag aatatcgtga tttagctgcc
     9541 catgcaaagc tagctgaaga agttggtatt tttccagaga atattcatat tctgaagcgt
     9601 ggcgatatca tggtgcttaa tgacgaaggt tttctccatg aaggaggtgt acctgccagt
     9661 gatgtcatga ttgacggtaa tgctatcggt gatgtgggta atatcgtttt acgagaccgt
     9721 aaagtcttgt cagaagatgg tattttcatt gttgctatta ctgtttctaa aaaagaaaaa
     9781 cgcattattt ctaaggctaa agttaatacg cgtggatttg tgtatgtcaa gaaaagtcat
     9841 gatattttaa gagaaagtgc agaattagtt aatacaactg ttggcaatta cttaaaaaaa
     9901 gatacctttg actggggcga attaaaaggg aatgtcagag atgatttgtc taaattctta
     9961 tttgaacaaa ccaaaaggcg cccagcgatt ctgccggttg tgatggaagt tcgttagtga
    10021 aaataggaag gttaggcaaa aactgcctac cttctttgat tttaacaact ggtaaaccag
    10081 gaaactgttc acccaaaaat acagtagatt tacgtgattg gattattttg gtataaagga
    10141 gtgtaatgaa tggcaagtat tgcaattgaa taccattcgg tagttttagg aatggagcgt
    10201 aaggtaaatg tgatttatcc tgaccagtct gaaatcccta aaaaagatca aggggataag
    10261 gatattcctg ttttatattt gttacatggt atgggaggca atgaaaactc ttggcaaaaa
    10321 cgaacagcta ttgaacgctt gttgcggcat accaatttga tagtcgttat gccttcgaca
    10381 gacctaggtt ggtatacaga cacggcttat ggacttaact attatcgggc gttgtcacaa
    10441 gagttaccgc aggtcttagc agctttcttt cctaatatga cccagaaacg agaaaaaacc
    10501 tttgttgctg ggctctctat gggtggctat ggtgccttta agtgggcact caaaagcaat
    10561 cggttttctt atgcggcatc gttttcaggc gctttggatt tttctcctga gaccttgctt
    10621 gagggaaacc tgggagaatt agcctattgg cagggcgttt ttggccagtt tgatgaccct
    10681 gaccttgaca agcattacct taaaaatatg gtggcagaaa gtgatggaaa aaccaaattt
    10741 tatgcttggt gtggctatga ggattttctt tttgccacta atgaaaaagc tattgctgat
    10801 tttcaggctc aaggtcttga cattgattat cataaaggtc atggtaaaca tgagtggtac
    10861 tattggaacc agcaattaga agtcctgtta gagtggttac cgataaacta ccaaaaagaa
    10921 gaaaggttgt cttaaccatt tcctagtaca acatgaggtg acaaatgaaa caattactgg
    10981 cgatcatatt gtggctgcct aagctaatag tgaaaatgtt ttggcatctt atcaaagggt
    11041 ttttacaaac tatcttatta gtaacgatta ttattatagg gctgatgtac tattctaatc
    11101 acagtgattc cgttttagcc aataagatct cgatagttac tgagcaagtg gtgcaaattt
    11161 ttgatatctt aacacaaaag ccatctgcaa agacgcgtca tgggagtggt aatagtcatt
    11221 ccactttcct tgttagcgct aaagaaggta atcaacgact taaaaagagt tcgatttctt
    11281 ttggaaacta ggctgaaaat gtcctcaaaa gggcattttt ttgttagaat gaaagtatga
    11341 ttattttaca aggaaacaag ttagaacgct ctttctcagg agatgttctt tttcaaaaca
    11401 tatcactgca agttgatgaa agagacagaa ttgcattagt ggggccaaat ggagctggta
    11461 agtcaacctt actcaagcta ttggttgggg aagaaacccc aacgagcgga gaagttaata
    11521 ctaaaaaaga cctaaccttg tcttatctgg ctcaaaatag ccgttttgaa tctgacaaaa
    11581 cgatatatga ggaaatgctc aaggttttcg aagcattacg ccaagatgaa aagcgtctcc
    11641 gtcagatgga aatggatatg gcaaccgttt caggtcagga cttgacacgg ctgatgatgg
    11701 attatgatct tttagcagaa cgttttcgtc agcaaggtgg ctttacatat gaagctgaga
    11761 ttaaagccat tttaaatggc tttaaatttg atgaaagcat gtggcagatg actatcgctg
    11821 agctgtcagg gggtcaaaac actcgtctgg ccttggctaa aatgctttta gaaaagccag
    11881 aactattggt ccttgatgag ccaacaaacc acttagatat tgaaaccatt gcctggttag
    11941 agaactactt ggccaattat caaggagctc taatcattgt gagtcacgac cgttattttt
    12001 tggataaggt ggcaacagtg accttggatt taactcctca tggattggat cgctacgttg
    12061 gcaattattc tcgttttatg accttaaaag ctgaaaaatt agtagccgaa gaaaagcagt
    12121 ttgacaaaca gcaaaaagaa attgccaagt tagaagattt tgttcaaaaa aatattgtca
    12181 gggcttcaac tacaaaacgt gctcaagcga gacgtaagca attggaaaaa atagaacgct
    12241 tagacaaacc gactagtgct agaaaatcag ctcacatgac ttttcaggca gataagccgt
    12301 ctggcaatgt ggtgttgacg gttgaaaaag ctgctattgg ttataaccaa catgttttat
    12361 ctgagcctat taacctagac gttcacaaat tagatgcgat tgctattgtt ggtccaaatg
    12421 gtattggtaa atctactctg attaaatctg ttattggaca gattcctttc atcaaaggag
    12481 aagtgaaata cggtgccaat gttgaaatag gttactatga ccaaacccaa tcacatttga
    12541 cgtctagcaa cacagttttg gaagaattat ggcaggattt ttcaactacg ccagaagtcg
    12601 atatcagaaa ccgattaggg gcttttctct tttctggaga tgatgtcaaa aaatcggtgg
    12661 ctatgctgtc aggtggagaa aaagcccgtc tgcttcttgc gaagttatct atggaaaaca
    12721 ataattttct tgttctggac gagccgacta accacctaga cattgacagt aaagaagtgc
    12781 tagagaatgc cctcattgac tttgacggta ccttgctttt tgtcagccac gaccgctatt
    12841 tcattaatcg tttggcaact aaggttctgg aaattaccga aaatggctca accctttact
    12901 taggtgacta tgattattac cttgagaaaa aggcagagct agaagaacta gcccgcctag
    12961 cagcaggaga gacagttgag gaaacaaaag aagcctctgc cactgattat cagctacaaa
    13021 aagctaatca aaaagagcgt cgtcgcttga cccgccgata tgaggagatt gaagcaagac
    13081 ttgaaaccat tgaagagcgc attggtgcta ttcaagaaga catgcatgcc tccaatgata
    13141 cggcgcagtt aatcgcttgg caaaaggaat gggaccaatt ggatcaagaa caagaaactc
    13201 ttatggaaga atgggaaacc atcgctgaac aaatagaatc ataaaaataa gctttagcag
    13261 ttttgctaag cttattttta tcgctttgtt acttgtttga aggtgtgaaa gaggttttaa
    13321 aatgatgtgt ttttttatgt caaggtcggt aaaacgtgaa actgttatat agtattttta
    13381 aattttttag tacagttttg tttgtaattt cacaaactat tgcatttcta aaaaaccaaa
    13441 taaggtaagg tagaaagcga tttaattatt tgcaaattgt gaaaaaaagt tttatcataa
    13501 aaaggtaata tgataatatg gaggccgaaa tggtaacagt ttctaaagaa caacatttgg
    13561 atatgttcct taaaatggaa cgtattcgtg aatttgattc acgtattaat aaactcgtcc
    13621 gtcgtggatt tgtacaaggc atgactcact tctcagttgg tgaagaagca gccaatgttg
    13681 gagcggtggc tcacttgtct tacgatgaca ttattttttc aaatcaccgt ggacatggac
    13741 aatcaatcgc taaagacatg gaccttaata aaatgatggc tgagcttgct ggtaaagcga
    13801 ctggtgtttc taaagggcgt ggtggctcaa tgcacttggc tgattttgaa aaaggaaact
    13861 atggtaccaa tggtatcgtt ggtggtggtt acgctcttgc agttggtgct gccctcaccc
    13921 aacaatacaa aggaactaac aatatagctg ttgctttctc aggtgatggc gctactaacg
    13981 aaggatcatt ccacgagtct gttaatatgg ctgcaacatg gaaacttcct gttattttct
    14041 tcatcatcaa caaccgttat ggaatttcaa tgagcatcaa taatgcaaca aatacaccac
    14101 atttatacac acgtgcagaa gcttacggaa ttcctggttt ctactgtgaa gatggcaatg
    14161 acgtgatggc tgtctatgaa acaatgggca aagccgttga acatgttcgt ggtggaaatg
    14221 gtccagctat tgttgaggta gaatcatacc gttggtttgg tcactcgact gcagatgctg
    14281 gtaaataccg tactaaagaa gaagtggatg agtggaaaga aaaagatcca atgatcaaat
    14341 atcgtactta tctgacaagc gaaggcattg ccactgatga cgaattggat gctattcaag
    14401 cacaagtcaa aaaagaagtt gacgatgctt atgaatttgc acaaaacagt ccagatccag
    14461 aactttcagt agccttcgaa gacgtttggg ttgactaaga tcaccttgtc agtaagaagc
    14521 aatcgtattt gaataataaa tggagaaata aaaatgatgt cagaaacaaa attaatggct
    14581 ttgcgtgaag cagtcaacct tgctatgact gaggaaatgc gcaaggacga aaacattttc
    14641 cttatgggag aagacgtagg ggtttacgga ggagacttcg ggacttctgt tggaatgatt
    14701 gaagaatttg gtcctaaacg tgttaaagat accccaattt cagaagctgc tatctctggt
    14761 gcggctattg gtgcagctat tacaggacta cgtccaattg tcgacgttac ctttatggat
    14821 ttccttacca tcatgatgga cgctatcgtg aataatggtg ctaaaaataa ttacatgttc
    14881 ggtggaggcc ttattacccc tgtaaccttc cgtgtggcat caggttctgg tattggttcc
    14941 gctgcgcaac actcacaatc tcttgaagca tggttgactc acattccagg aatcaaagtt
    15001 gttgctcctg gtaatgccaa cgatgctaaa ggcttattaa aatcagctat ccgtgataat
    15061 aacattgttc ttttcatgga accaaaagcg ctttatggta aaaaagaaga agttaaccaa
    15121 gatcctgact tctatatccc acttggcaaa ggtgacatca aacgtgaagg aactgatttg
    15181 acaattgtgt catatggtcg tatgttggag cgtgtccttc aagcggctga agaagttgca
    15241 gcggatggta ttaacgttga agttgttgac ccacgtaccc tcatcccact tgataaagag
    15301 ttgattattg aatctgttaa gaaaacaggt aaattgatgc ttgtcaacga tgcctacaag
    15361 accggtggat tcattgggga aattgcaacc atgattactg aaagtgaagc ctttgattac
    15421 cttgatcacc caatcgttcg tcttgcaagt gaagatgttc cagtacctta tgcacgtgta
    15481 cttgaacaag cgatcttacc agacgttgag aaaatcaaag ctgccattgt gaaaatggca
    15541 aacaaaggca actagaagat aaggcaagtg gtctgataaa ggctatgttt atcagtaacg
    15601 tctcagctaa aaactatttt gaaagttttt agaagaactg agttgtctta tcccgtgtcg
    15661 cggcacctca cctttcgtat gttttcgtag caaggtgggg atgttgatgg cgcttatcaa
    15721 atcgtgaaag gatgtagaaa tggcatttga aattattatg ccaaagctgg gcgttgacat
    15781 gcaagaaggc gagatcatcg agtggaaaaa acaagaaggt gataccgtca atgaaggtga
    15841 tatccttctt gaaatcatgt cagacaaaac caatatggaa cttgaggcag aagactcagg
    15901 tgtgctattg aaaattgtcc gtccagctgg tgatactgta cctgtaactg aagttatcgg
    15961 ttacattggt gcagagggtg aatcagtaga tactattgct tcaagtgaaa aaacaacaga
    16021 aattccagtt cctgcttcag cagacgctgg accagcagtt gctccaaaag aaaatgtggc
    16081 aagtccagct cctcaagtgg cagcgacagc tattccgcaa ggaaatggcg gaaaagttcg
    16141 tgctactcca gctgcacgta aggcagcagc agaaatgggc attgaccttg gccaagttcc
    16201 aggaacagga ccaaaaggac gtgtccataa agcagacgtt gaaaacttta aaggtgctca
    16261 accgaaagct tcaccacttg ctcgtaaaat tgcagcagac aaaggtattg atttggcaac
    16321 cgtatcaggt actggcttta acggtaaggt catgaaagaa gatatcatgg ctattcttga
    16381 agcggctaaa ccagctgaag caaaagcccc agcagctaaa gaagaaaaag ttgttgatct
    16441 tgcagaaggt gtggaacaca agccaatgtc agctatgcgt aaggcaatct ctaaaggtat
    16501 gacaaactct taccttactg ctcctacctt tacgcttaac tacgatattg acatgacaga
    16561 gatgattgcc cttcgtaaga agttaattga cccaatcatg gctaaaacag gccttaaagt
    16621 cagcttcaca gacttgattg gtatggcagt ggttaaaacc ttgatgaaac ctgagcatga
    16681 gtacatgaat gcttccctca tcaatgatgc taatgatatt gaattacacc gctttgtgaa
    16741 ccttggtatt gccgtaggtc ttgatgatgg tcttatcgtt cctgttatcc atggggctga
    16801 caagatgagc ttgtcagatt ttgtgcttgc ttcaaaagat gtgattaaaa aagcgcaaac
    16861 tggtaagttg aaagcagctg aaatgtctgg atcaaccttc tctatcacaa acttgggaat
    16921 gtttggtacg aagacattta acccaattat taaccaacca aactcagcaa ttcttggtgt
    16981 tggagcaact atcccaactc caacggttgt ggatggtgag attgttgccc gtccaattat
    17041 ggcaatgtgc ctaaccatcg accaccgttt agttgatggt atgaacggtg caaaattcat
    17101 ggttgatctc aagaaattga tggaaaatcc atttgaattg ttaatctgat caatcagttt
    17161 taaacaagaa aagcattcaa taataaaagg gattttgcta agtttagact tggtgggtgc
    17221 ccttttctca aaaatataga aaggatgtag aacgaggaga tctcatgcaa atgagtgata
    17281 agcaattgaa tccgagcgaa aagctcggat aaaaatggta agagttggct aatcttagcg
    17341 tcgtagacgt ctgaactttc ctcaattttt gtttcggaaa gtcctagtcg tcctgacgtg
    17401 ggtgcgtcaa cgaaatcaaa gatttctgac ttaccgcaaa aattcaatcg ctttctcctt
    17461 gctcttggta tcttaaatta tggctgttga aattattatg ccaaaactcg gtgttgacat
    17521 gcaagaaggt gaaatcatcg agtggaaaaa acaagaaggt gatactgtca atgaaggcga
    17581 tattcttctt gaaatcatgt cagataaaac caatatggaa cttgaagcag aagactcagg
    17641 tgttcttctt aaaattacac gtcaagcagg tgaaacagta cctgtaacag aagttatcgg
    17701 atatatcggt gctgaaggtg aatctgttga ggtttctagc ccagctgctt cagatgtgaa
    17761 tgttgctcgt acaacagaag atttagaagc tgctggactt gaagtgccaa aagcaccagc
    17821 tcaagctgct tcagctgcac caaaagctgc acttgctgat gatgagtatg acatcatcgt
    17881 tgttggtggt ggccctgctg gttattatgc agctattcgt ggtgctcaac ttggtggtaa
    17941 aattgccatc gttgagaaat ctgaatttgg tggaacttgc ttgaacgtag ggtgtatccc
    18001 aaccaaaact taccttaaaa atgctgaaat ccttgatggt attaagattg cagcaggacg
    18061 tgggattaac cttgcctcaa ctaactatac cattgacatg gacaaaacag ttgactttaa
    18121 aaacaccgtt gttaaaacct taacaggcgg cgttcaaggt cttctaaaag ctaataaagt
    18181 cactatcttt aatgggcttg gtcaagttaa ccctgacaag actgtaacca ttgggtcaca
    18241 aaccattaag ggtcgcaacg ttatccttgc tacaggttct aaagtatcac gtatcaatat
    18301 cccaggaatt gactctaaac ttgtcttaac gtctgacgat atccttgacc tccgtgaaat
    18361 gccaaaatca ctagcagtta tgggcggtgg tgttgttggt atcgagcttg gacttgtttg
    18421 ggcatcttac ggtgtggatg ttaccgttat tgaaatggct gaccgcatta tcccagctat
    18481 ggataaggaa gtctctcttg aacttcaaaa aatcctttct aagaaaggca tgaagatcaa
    18541 aacatctgtt ggtgtctctg aaattgttga agcaaataac caattgacct tgaaacttaa
    18601 caatggtgaa gaagttgtcg ctgaaaaagc tcttctttct atcggtcgtg taccacaaat
    18661 gaacggtctg gaaaatctta accttgaaat ggatcgtaac cgtatcaaag ttaatgacta
    18721 ccaagagaca tcaattccag gtatctatgc gccaggtgac gttaacggaa cgaaaatgct
    18781 tgctcacgct gcttaccgta tgggtgaagt ggctgcagaa aatgcgatac atggcaacac
    18841 aactcgtaaa gctaacctta aatacactcc agcagccgtt tacacacacc ctgaagtggc
    18901 aatggttggt ttaactgaag aacaagcgcg tgaacaatat ggtgatgtgc ttattggtaa
    18961 aaacagcttt actggtaatg gacgtgcgat tgcttcaaat gaagcccatg gttttgttaa
    19021 agttattgct gatgccaaat accacgaaat cttaggtgtt catattattg gtccagctgc
    19081 agctgagatg attaacgaag cagctactat tatggaatct gaattaaccg ttgatgaatt
    19141 gttattatca attcatggac acccaacctt ctctgaagtg atgtacgaag cctttgcaga
    19201 tgtgcttggc gaagctatcc ataacccacc aaaacgtaag taaaacgtct ttgtcttatt
    19261 aactaatgaa aaatatcatc acataacaga tcacaaaaaa gactagcaca actatgaact
    19321 gcaccccaaa cgttagatat aaaaccctaa cgtttggggt gtttttgtat gacattaagc
    19381 tatgaagata agctagacat ttagcgctaa aaaaacgaga gaactccgtt tgaaagaagc
    19441 atctctgaaa agaagaagac aaaaaaccat tataaagaat ggacaaagac gagctctgat
    19501 tagattttct tttaaggacg gctaaagtga ctcgttctac ctactattat catcgattat
    19561 tgcaccaata accgtatcaa aataaaacga aaaggactta gtcctctaca atacagaact
    19621 aaatccttta cttcaaatag agtagccaac ttttggggct cagtgcagtt tccagttttt
    19681 tgtctttaat aacgtttcat tgttaaccct tactttccaa taacagctaa atccttaagt
    19741 ctttcttacg aaagggtttt gtgatatggt taaaagaagc aactaaagct ccacctaaga
    19801 attctaaaga ggaggactga tacccagtat gcggtaagcg tcgttgtctt ttgtggggaa
    19861 ttttatgaga gttaagagca ttgtttttag ctgcaattcc ttgatgagca agcttttatt
    19921 gttgattttg cttgacagga tgaggaaaac tataaaagcc ttgatgagaa agattatgat
    19981 ttgaaaacat cgttgctttt ttttcatagt gaatgacgtg catctgttga ctatcatgat
    20041 cgtagacagc ggccagtttg tcattgtttt ctaacaagtc gatatcaagc ttgctaatat
    20101 aggtttcaaa ttcttgacga gtcatatttg gaagcatcat ataggcataa cgatcgccat
    20161 cttgagtatg gttttgcatg atagtgataa aggtatttga aacttctttg atggcttctg
    20221 gtgatttgtc atcagctttt atgttttgcc atttccctgt ttgaagtgcc ttacttatgc
    20281 taagtgttgt tggcttgaag aagtagtaac caatattttg agcagaatca tcactttcaa
    20341 ggaaaatact tttagtgttt gtaaaatcaa ctagctgatt attcaagtca acgggttgat
    20401 tgttaacata agcatggtaa gggtgctttt gattttcttt tcgttgttca atagttgtat
    20461 acgccttgtg agatgattgg tttttgatat tgctaccaac aaagattatt ttgtttccta
    20521 agataaacca ccctttattg agagtgaggc ttttattcca attagtgaag gtcatagcag
    20581 ctagagcact tgtgttatta agttttttac ttgcaacaaa agcgtcatca gagagactag
    20641 tcatgccaac ttgttgatag ttcgttttaa tattctcagg agttccctct agtggttttt
    20701 gctcagtttc tgtggttcca ggtaagcggt agggatttac agttgcccaa tagttttcac
    20761 tgtagtgtcc taaatcgtta ttgtataggt aaaacattcc atcagaagta aaccagccat
    20821 gaagattttc attattcata gcttcataat tttgagttcg attcgaaaac attgataggc
    20881 caaaagcaaa atcgtgttta ttattatata gtgccaattt atccatacta ttgaaactag
    20941 ctacgtaact atcaagtttt tggactggaa cagaagtatc acttagcagt tctttcataa
    21001 gtttgatatc gtgataggtt ttcaaattat catagacatt gtaaaaagca ttcccttgtg
    21061 tgacgagtgt ttttatacgt gttttaagtg ccaaacggtg aggctcttca gacatgtcag
    21121 caatacgtaa aatagcacga agtgcttcaa tgccagcaac atgagattga gcattaaaac
    21181 gactgataga acgccctcga gtcatatcca tcatttctcc acgaacgatg atagggaaaa
    21241 aagaatggtt aatccaatga tagatagtag ccattttatc cgcttctata gaagactttg
    21301 ttttttgaat aataggaatt aattgcgata agccatctat aagaacatta ccgtaagctc
    21361 cagtgtaagc aatgcctttt ttataaagtg gactttgagc gttagtaacc acgtgatcaa
    21421 ttaaagaacc gtcttggtaa aaaccatttc cttcgtcaac tagcgtgaaa actttctcaa
    21481 ttgctttgat tgtatcacta atttcgagat catctttacg aagaataccg gaaatgagtt
    21541 taacacgccc catatcaatt aaatttccgc tattggcttc aaaaggtgaa aaattggcag
    21601 cgcgaaccct aaaacgagta gggtcaggca caaatttttc gattggagct gtgtatttaa
    21661 ggatttcttc ttgagtaaaa taaagataca tcaaggataa ggtattatta atagcacgag
    21721 gagttccaat ttcataaacc caccaatttt ctttgttttc ttttccagtt gtttgatgat
    21781 tttcacgatc tagattataa gcgtgttcat acatgaaggc cataccgtct tttacaatag
    21841 caatagcttt actatcttga taatagcatg actcaggatt agtgatctgt tttgctattt
    21901 tttcaatatt gcggtaagtt ttcgtgatat tagcagaagc ggaataatcc tttgcatgtt
    21961 cccaaaggta agttctattt tcgtggtcag gcccttgata gcttttaata atgttttgag
    22021 catccttttc agctttatta tgaaaagtga ccatgtcagg attggtttta tcataagcat
    22081 cgttgcctgc gataatactg ttccattggt ctaacaattc agtatagtag tctttttgtt
    22141 gtggctgtac tacctttttt tcgctatctg tagtagtgag catttgcgtt tgaaagtaag
    22201 tattattagg ttctgaattt gaagtcagtg tatcggcata aatggcagtt ccttggccca
    22261 tcatagcaaa gctaaggaat aggtttgaat aaagtagtaa ttgtttatgg tgtgtgcaaa
    22321 aataagtatt cactgataaa ttcctcctat ataaaaatga gataataaaa gtaaattggt
    22381 ttactaagta aaaatatacc acgttaaagt atttttataa acccttacat aaataatggc
    22441 tgagtttttg tgcactaata agtgtaggta ctgaagatgt catacagaat aggacacttg
    22501 tcttttatat ttgttttcat tatactagaa aggtagatta catttttgaa aggatttttt
    22561 ctcctatgaa atacatcgtt aacaaaagtc acaatcctgc ctttaacatc gctttggaag
    22621 cctatgcttt tagagaacta gtggaagaag acgaattgtt tatcctttgg atcaatgagc
    22681 cagctattat tattggcaaa catcaaaaca ccattcaaga aatcaataaa gaatacattg
    22741 atgaacatgg tattcatgtt gtgcgacgtt tatctggtgg tggtgcggtt tatcatgatt
    22801 tgaataactt gaactacact atcatttcaa ataaaacagc ggaaggcgca tttgatttca
    22861 aaaccttctc acaacctgtg attgcgactt tagctgattt gggtgtaaca gccaacttta
    22921 caggccgtaa tgatattgaa attgatggca aaaaaatctg tggtaatgct caagcttact
    22981 acaaaggtcg catgatgcac catggttgcc ttttgtttga tgtggatatg accgttcttg
    23041 gcgatgctct taaggtaagt aaggataaga ttgagtctaa aggagtgaag tctgttcgtg
    23101 ctcgcgtgac caatatttta aatgaattac cagaaaaaat taccgttgag gaattttcag
    23161 ataaaatctt gaccaagatg aaagaaacgt atccagacat gacagaatat gtcttgtcag
    23221 aggatgagtt ggctaagatt gaacaatctg ccaaagagca atttggtagt tgggattgga
    23281 cctacggcaa agcgccagaa tatacgattg aacgcaatgt tcgttaccct gcaggtaaaa
    23341 tttcaacctt tgcaaatgtt gaaaattcta tcattaaaaa ccttaaaatc tatggtgatt
    23401 tctttgggat caaagatgtg caagacattg agaacttatt aattggttgt aaatatgagt
    23461 accgtgatgt ttttgaatgt ttaaaaacga ttgatacgac ccagtacttc tcacgcatga
    23521 ccgttgaaga agttgctaaa gctattgttt cttagtggtt ttaatcactt aagaagctct
    23581 gtcagaagaa aaaactataa aactcctaag cgaactatct atcgtgtcct gcttaggagt
    23641 ttttgtttga tgacatgaaa gaagaactta aactttatta aaggaagctt tgcttttaag
    23701 gtcggcatat tcttcagtga tttcttgttt cagtatatca tcatagctag gtagtgaaat
    23761 agctgatcca tacttttttt taagagatgt tgttactaag cggtaagcaa gattaacatt
    23821 gcgtgataag ataggaccgt ggaaataact accatagacg tttttatagt gaacaccttc
    23881 agtttggtct tctttattat taccgttgcc ataaaccact cgtccaagtg gcttttcgtc
    23941 accagataag aaggtacgtc cttgatgatt ttcaaagcca taataggttt cgttaaattc
    24001 gtcattatga attttaatat ctccaataaa gcgattttgg tgctgattaa gggtgtagtg
    24061 tcccataatt ccaagtccat caattttaac cccattagct tggacatagt attgccctag
    24121 taattggaag ccaccacaga tggcaagcac cactttatta ttagcaatgt aatctgctaa
    24181 ggcagctttt ttgctaggca aatccttggc aacaatgctt tgttcataat cttgaccacc
    24241 accaaagaaa acaatatcgt aatcgtcttg ttcaaaggta tcattgatag atacaatatc
    24301 aacagtaacc ctagctccaa gtttttcagc gacatacttg agcatcaaga cattcccatt
    24361 gtcaccgtag gtattcatca ggtttccgta gagatgagca atgtttaggt catagaggta
    24421 gtcagtgttt tctggagatt ttagtgaagt gtaagtcatt agttcatctc cttttcaaca
    24481 acatggcggt cggctagcaa gctacggaat tctaacattg cagtataggt tgctaaaata
    24541 taagcatgtt tgctttcttg tttttcaata gcttccatga tttgctcgag cttttcagct
    24601 tgttttatct tagtgtcgtc aaatcctgtg actctaagtc ttctggcaat ttcagagtga
    24661 cggacgccgc cagcattaat ttctgtaatg ggcatttggg taatgagttc aaaattagca
    24721 tcccaaatcc agctggtatc aatgccgtca gcgtaattag catttaaaag cacagataag
    24781 ctaaatgggt aatcagctag ctgaatcatt tcaagcgctt gactggctcc aacaggattc
    24841 ttgataagga taagggtgca tgatttatca ccaatagtaa aagtttcttg tcttccaaaa
    24901 accgccttac ttttgttaaa gcccgccttg attttctcgg gagaaacacc gaaaaattca
    24961 gcaacagaaa ccgcagcaag cgcattgtaa atattataaa gaccaccaac atttatcttg
    25021 tagttttgtc catcaataac aaattcagaa ctttggtgag taatagcggt gagttcagtt
    25081 aatcgataat ccaactgtgg tctcttgaag ccacaattta aacaaataaa gtctcctaga
    25141 ttcgcataag tattgagacg atactgaaga atatgttcgc attttggaca taaaatccct
    25201 tctgtgttgt aatgagctag ctgcggagca tgcttagcag tatcaaaacc ataatactga
    25261 actggattaa ctatgtcctt agaagagaaa ataggactat ctccattggc tagaatagtt
    25321 gcttttggag catttcgagc accatctaca atcatctgat aagtagtata aatctctccg
    25381 tagcggtcca tctgatccct aaaaatatta gtataaacaa aaagactagg ttttaagtaa
    25441 gtggtaattc taggaagact agcttcgtca atttctaaaa cagcaatttg ccttccagat
    25501 ttcccttttt tagcagctaa aaaagtagaa gtaattccag taatcatatt ggcaccactt
    25561 ggatttgtga ttatctcgcc aaatgcctct ttcaaaatac cgacagtaag agcagttgtt
    25621 aacgttttac cattagtacc agtgacgacc acaatatcat agtccttaga caaatccttt
    25681 aaaatatctt tattacaagc tagagccaat cgaccaggat aagtagatcc tcgccctagt
    25741 tttgttaaaa tggattgagc agctttgcca gcaataatgc cgagtaatgt cttcattttc
    25801 atgcttatat tttatcataa gtttattgat tttagatagg gaaaaatctt tgatcatgat
    25861 atgatataat atagctaata acttttttga tatagaaatg agagttgtat gaataattta
    25921 tctagtatcg atattaaatt tttattaagc ttatttgcgg atccttggct gctggcagtg
    25981 catcttttag atattctaat tgttgcctat ttgatttatc gttttattaa agcattgact
    26041 ggaactaaaa tcatgtcttt agttcaaggg gtcattttct ttttggttct tcgttttatt
    26101 gcagagtgga ttggctttac gacaatcaca tacttaatga accaagtcat tacttatggt
    26161 gtaattgcag gagtagtcat ttttacccct gaaattcggg caggactgga gaaatttggt
    26221 cgttctacgc aagttttttt acaaaaacag tacgtcagca gtgaatctgc tttggtcgat
    26281 gctttgatta aatctgtggc ctatatgggt ccacgcaaga taggtgcatt gattgctatt
    26341 gaacagactc aaaccttaca agaatatatt gcgacaggaa ttccgctgaa tgccgacatt
    26401 tcaagtcaac tactcatcaa tatttttatt ccgaatacgc cgcttcatga tggagctgtt
    26461 atcgttggtc agaataagat tgtggcagcc tgtgcttact tgcctttgtc agaatcaaag
    26521 gcaatttcca aagaatttgg gacccgtcat agagcggcta ttggattatc tgaaaactct
    26581 gatgcactaa ctatcattgt ttcagaagaa acaggagcta tttcagtaac tcgcaaaggc
    26641 caatttttac atgatttaag cacagatgaa tttgaaacgg tacttaggac ctacctgatg
    26701 agtgattcaa atgttagttt accatggtat aagaaaattc taggagggaa atctaaatga
    26761 aacgattttt aaatagtcgt ccttggttag gaatggtatc agtctttttt gcgattctcc
    26821 tttttttaac tgcagcatcg agcaatcata ataattctag ctcgcaaatt tatagcccga
    26881 ttgaaaccta tacgcatagc cttaaagatg taccaattga tatgaagtat gatagtgaca
    26941 aatattttat cagtgggtat tcttatggtg cggaagttta tctaacctcc actaatcgta
    27001 tcaaattaga ttctgaagtg aacaatgata cacgtaattt taagattgtg gcggatctaa
    27061 cacatagtca tccaggtaca gtaaatgtca acctaagagt agaaaacctt ccttctgggg
    27121 tgacagctac cgtatctcca gataaaatat cagtcacaat tggcaaaaaa gaatctaagg
    27181 tatttcctgt tagaggaagc gttgatgcta aacaaattgc aaatggttat gaaattagca
    27241 aaattgaaac gggggttaat aaggttgaag tgaccagtga tgaatctacc attgctttaa
    27301 ttgatcacgt tgtggcaaag ttacctgatg atcaagtgtt agataggaat tatagtagtc
    27361 gagtgacctt acaagctgtc tcagctgatg gaactatttt agcaagtgca attgatcctg
    27421 caaaaacaaa tttatcagtt gctgtaaaaa aaataacgaa atcagtcccg attagagttg
    27481 aggcagtggg gatgatggat gatagcttat cagatattca atacaaattg tcaaaacaaa
    27541 cagctgttat ctcaggtagt cgagaggtct tagaagatat tgatgaaatt attgcagaag
    27601 ttaacatttc tgatgttact aaaaatacta gtaagaccgt gagtttgtct tctagtcagg
    27661 tgtcaattga gccgtcagta gtgaccgttc agttgacaac caccaaaaaa taatggataa
    27721 taactaggaa aattgaatgg aggaagccat taggcttata taaattatgg gaaaatattt
    27781 tggaacagat ggtgttcgtg gcgaagcaaa tgttgagctg acacctgagt tagcttttaa
    27841 actgggccga ttcggtggtt atgttttaag tcaacatgag accgaaagac ctaaagtttt
    27901 tgtggcgcgt gacacccgta tttcaggaga aatgttggag tcagccttga ttgctggtct
    27961 actatctgtt ggtattgaag tttataaact tggcgtttta gcgacacctg gtgtctctta
    28021 tttagttaga acagaaaaag caagtgcagg tgtgatgatt tctgcaagtc ataaccctgc
    28081 gcttgacaat ggcatcaaat tctttgggaa tgatgggttt aagttagctg atgaccaaga
    28141 attggaaatt gaagctctct tagatgctcc ggaggacacg cttcctcgcc cgagtgcaga
    28201 aggacttgga accttggtag attatccaga aggacttcgt aaatatgaaa agttcttggt
    28261 aacaactggt actgacttaa gcggtatgac agttgcctta gacactgcta atggagctgc
    28321 ttcagtgtca gcacgtgatg tctttttaga tttaaatgca gaaattgctg tcattggtga
    28381 aaaaccaaat ggtcttaata ttaatgacgg tgttggttca acgcatccag aacaacttca
    28441 agagttagtt aaggaaacag gagcagatct tggtttagcc tttgatggcg atagcgaccg
    28501 tctgattgcc gtggacgaaa ctggcgagat tgttgacggt gatcgtatta tgtttatcat
    28561 tggtaaatac ttgtcagaaa aagggcttct tgctcacaat accattgtca caacggtgat
    28621 gtctaacctc ggttttcata aagctttaga taaacaaggt attaataaag caattacagc
    28681 agttggagac cgctatgtgg ttgaagaaat gcgtagctca ggatacaatc ttggtggtga
    28741 acaatcaggc catgtcatta tcatggacta caataccact ggagatggtc agttgacagc
    28801 tatccaatta gccaaggtga tgaaggaaac tgggaaatca ctttcggaat tagctgctga
    28861 agtaaccatt taccctcaaa aactggtgaa tattcgtgtg gaaaacagca tgaaagaccg
    28921 tgctatggaa gttccagcta ttgcgaacat cattgcaaaa atggaggatg aaatggctgg
    28981 taatggtcgt attctcgtga gaccaagtgg tacagaacct cttcttcgtg tcatggcaga
    29041 ggcgccaaca gatgccgaag ttgattatta tgtcgatact attgctgatg tcgtccgtac
    29101 agaaatcgga tgcgataact aacgagttga gtacaaacaa gaaaccttat ttctaaggct
    29161 tctgtcaaca attggaaaga ggcttggggc gtttagccca agtctctttt tataaattgc
    29221 taaagtagaa gagaaaggat atcggatgac aaaacagcaa atcgaaaaac tagcggactt
    29281 actgcctcct tttgcagcca cactttactt agatatgatt cctgaatttc aggaaggtta
    29341 tgcttcatat gtttatcaaa caccaaaaca agatattcaa aagcgccgca tcaagcagtt
    29401 aactaaaaat tttgaacgat tactagatac cccatctttt tatgtgatgc ctgtgacaag
    29461 aaaaacagca gagcaattgc tagcagataa aggcctagct tatcatttgt tatcgacagt
    29521 tgcagctaat caagtgtttg cggctgctgt taacgaggat cagacgcttt ttcaagtgct
    29581 tcgaaatgga gcaagagtag cctttgtgat tcttcaagaa aagggggaat ttctagaaat
    29641 gactttaggg attcttgaaa cagtgacaga aaacgaggtt ccagcggcta ttgtggaggc
    29701 tgtccagaca tatcttctgg cagatatgca agagaacctc ccttctttaa gcattatggt
    29761 cagtcaagaa tcaagcaagc ttttttacca agaacaagga tttgttttgc tagctaaggg
    29821 ttgcaagcca ggaaacgaaa atgattctga cgtttgtcag ctcgtaaaat atttttccag
    29881 gccatgaaga atcaagggaa atggcttatt catagaaaca ttttatcatc aaagtggtat
    29941 aataagacca tgtcaaaaaa acctacttca gcctatgtgc acattccttt ttgcacacaa
    30001 atttgttatt attgcgattt ttcaaaagtc tttatccaaa atcaacctgt tgatgcttat
    30061 ttgaaagcct tgattcaaga atttgactct tatggcattc gagacctaaa aaccctttat
    30121 attggaggag gtacgcctac agctatcact gctaaacagt tggagtatct cctaaatcac
    30181 cttgaacgaa acctcaattt agatgatctt gaagaattca caattgaggc aaatcctggt
    30241 gatttgacgc cagaaaaaat tgcggtgctt cagaggtcag ctgtcaatcg gatttccttg
    30301 ggggtgcaga cttttaataa caagcaatta aagcagattg gccgtagcca taatgaagaa
    30361 caaatttata gcaccattgc caatttaaaa actgcaggct ttcacaatat ttccattgat
    30421 ttaatttatg ccttgccagg tcaaacctta gatcaagtca aggaaaatgt tgctaaagct
    30481 ctggcacttg atattcctca ccttagtctt tatagcctta ttttggaaca tcacactgtt
    30541 tttatgaaca aaatgcgacg tggtaaactt aacttaccaa cggaagactt ggaagcggaa
    30601 atgtttgagt acattatttc agaaatggaa gctaatggtt ttgagcatta tgaaatttcc
    30661 aattttacca aaccaggttt tgaaagtcgc cataacttga tgtattggga taatgtggag
    30721 tattttggat gtggtgcagg ggcttcaggt taccttaatg gcattcgtta tcagaatcgg
    30781 gtgcccatcc agcattatct taaagcggtt gaagcaggga atgctagact aaatgaagaa
    30841 gtgctgcgca aagaggaaat gatggaagag gaactctttt tgggcttacg taaaaagaca
    30901 ggagtctcca tccagcggtt ccaagaaaaa tttggtgttt cttttgagga gcgttatgga
    30961 aatattgtta gggagcttca aaaccaagga ctgcttgtca aagatgacgc ttttgtcaga
    31021 atgactaaaa agggtctttt cttaggtgat tctgttgctg agcggtttat attagattag
    31081 gagagtatta tgggattaag ttatcaggag gagttgacac ttccttttga attatgtgat
    31141 gtcaaatcag atataaaatt gcccctttta ttagactatt gtttgatggt ttctggtaga
    31201 cagtctgcgc aattaggacg aagtaacaac aaccttttag tcgattacaa gcttgtttgg
    31261 attgtaacgg attatgagat cactattcat cgcttgccac attttcaaga aaccatcacc
    31321 attgaaacaa aagccctctc ctacaataaa tttttttgtt atcgccaatt ttatatttat
    31381 gatcaagagg ggggtctttt agtggatatc ttagcctatt ttgctttgtt aaacccagat
    31441 acgcgaaaag tggcaactat tccagaagat ttagtagcgc cttttaagac tgattttgtt
    31501 aaaaagccac accgtgttcc taaaatgcct cttttagaac aatcaattga tcgtgattat
    31561 tatgtgcgtt attttgatat tgatatgaat ggtcatgtca acaacagtaa atatttagat
    31621 tggatgtatg atgtgttggg gtgtgagttt ttaaaaacgc atcagcctct taagatgact
    31681 ttgaaatatg ttaaagaagt ctcaccaggc ggtcaaatta cttccagtta ccatttggat
    31741 caattaactt cttaccatca aatcacctca gatgggcagc tgaatgccca agccatgatt
    31801 gaatggcgag cgattaaaca aacagaaagc gagacagact agtgccttat aagggttatt
    31861 taattgattt agacggaacg atttaccaag ggaaaaaccg tattccagca ggggagcggt
    31921 ttatcaaacg cctacaagaa agaggcattc cctatttatt agtgactaat aataccacaa
    31981 gaacacccga aatggtgcaa agcatgctgg ctaatcagtt tcatgttgag acaggcattg
    32041 agaccattta tacggctacc atggcaaccg tcgattacat gaatgacatg aaccgtggca
    32101 agacagctta cgttattgga gaaacagggc tcaaatcagc tattgcagca gcaggttacg
    32161 tagaagaact tgagaatccc gcttacgtgg tggttggttt agacagtcag gtgacctatg
    32221 agatgttggc tatagccacc ttggctattc aaaaaggtgc cctctttatt gggacaaatc
    32281 ctgatttaaa cattccaacc gaacgtggtt tgatgccagg agcaggtgca ttgaatgcct
    32341 tactagaagc tgccacacgt gtaaaacctg tttttattgg caagcccaac gctatcatta
    32401 tgaataaatc actagaggta ttgggcattc agcgctctga ggctgtcatg gttggcgata
    32461 attacttgac tgatatcatg gcaggtattc aaaatgatat tgcaacgatc ctcgtgacaa
    32521 caggctttac cagacctgaa gaggtaccaa ccttaccaat tcagccagat catgtcctat
    32581 ctagccttga tgagtggagg ttgtgatggt agaaaacact aaattactat gtagctgggt
    32641 atggttatta gcgttagcta ttctcataac gatctattca acgtggctgt ggtatcctct
    32701 tgaggtggac catctaaagt tagaacaagt tgtttttatg agcaaggatg ctatcttgca
    32761 taactataac ggactactaa attacctcac caatcctttt gtgacaaggt tggaatttgc
    32821 taattttcac tcatcagcag acggactcaa gcattttgca gatgtgaagt ggctttttca
    32881 cctaactcaa gtcgtttttc ttggcctcct ttacccaacc cttaagactt tcacacaaag
    32941 gttaaaaacc aaacgtttct ggctccttca aaaaccttta atactagcag ctttgtttcc
    33001 tcttatgatt ggtctaatgg ctagtttcat tgggtttgaa cattttttta ctctttttca
    33061 tcaggtgctt tttgtaggag atagcagctg gctctttgat cccttgaaag atcctgtgat
    33121 ttggatcctt ccagaagtct ttttcttgca ctgtttcctt ttctttatga tagtttacga
    33181 aatcatcctg tggagcttag taggtttagc aagatggcag cgcctaaatg tagaatgata
    33241 aaacaagcgt tttgaaagcg cttgtttttt agtttgcagt cagagtagaa tagaagtatc
    33301 aaaaaaaagc accgactcgg tgccactttt tcaagttgat aacggactag ccttatttta
    33361 acttgctatg ctgttttgaa tggtcccaac aagattattt tataactttt ataacaaata
    33421 atcaaggaga aattcaaaga aatttatcag ccat
//
LOCUS       DATWEK010000017        32341 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.017, whole genome shotgun sequence.
ACCESSION   DATWEK010000017 DATWEK010000000
VERSION     DATWEK010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32341
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.017"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            215..967
                     /locus_tag="VCR92_000996"
     CDS             215..967
                     /locus_tag="VCR92_000996"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEP4268077.1"
                     /translation="MIDIMSDFQNKTCSKNNFIVGPCSIESYDHIRLAASSAKKLGYN
                     YFRGGAYKPRTSAASFQGLGLQGIRYLHEVCQEFGLLSVSEIMSERQLEEAYDYLDVI
                     QVGARNMQNFEFLKTLSHIDKPILFKRGLMATIEEYLGALSYLQDTGKSNIILCERGV
                     RGYDVETRNMLDIMAVPIIQQKTDLPIIVDVSHSTGRRDLLLPAAKIAKAVGANGIMM
                     EVHPDPDHALSDAAQQIDYKQLEQLGQELWQD"
     gene            1023..2096
                     /locus_tag="VCR92_000997"
     CDS             1023..2096
                     /locus_tag="VCR92_000997"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEP4268078.1"
                     /translation="MPQTLHVHSRVKDYDILFTDHVLKTLADCLGERKQRKLLFITDQ
                     TVYHLYQTLFEEFAQQYNAFVHVCPPGGQSKSLERVSAIYDQLIAENFSKKDMIVTIG
                     GGVVGDLGGFVAATYYRGIPYIQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPE
                     AIIISTTFLETLPQREFSCGISEMLKIGFIHDRPLFQQLRDFQKETDKQGLERLIYQS
                     ISNKKRIVEQDEFENGLRMSLNFGHTLGHAIESLCHHDFYHHGEAIAIGMVVDAKLAV
                     SKGLLPKEDLDSLLQVFERYQLPTTLERADVSATSLFDVFKTDKKNSEQHIIFILPTE
                     TGFTTLAINKDDHQFVEKLDSLL"
     gene            complement(2531..2836)
                     /locus_tag="VCR92_000998"
     CDS             complement(2531..2836)
                     /locus_tag="VCR92_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEP4268079.1"
                     /translation="MIENLSQLVQYHDHQVASRSLSRLLGLSQSIVLYAMAQGESISQ
                     ETSPRDKVILVLEGQLIFDLEDQKQVLTQESLIAIPAQKAHHLEAKTDCKLLQVLLD"
     gene            complement(2838..3176)
                     /locus_tag="VCR92_000999"
     CDS             complement(2838..3176)
                     /locus_tag="VCR92_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002265614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEP4268080.1"
                     /translation="MSYINNIEHAKVLDLTQEVMIEQDQMLSRTLVQRQDLGITVFSL
                     DKGQEIGRHSSPGDAMVTILSGLAEITIDQETYRVAEGQTIVMPAAIPHALYAVEAFQ
                     MLLVVVKPEA"
     gene            complement(3229..3984)
                     /locus_tag="VCR92_001000"
     CDS             complement(3229..3984)
                     /locus_tag="VCR92_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEP4268081.1"
                     /translation="MVTKEVGHDFLARLGKKRLRPGGVEATNWLIEQGQFSQDCHVLE
                     VACNRCTTAIELAKTFGCQIDAVDLNPKVVKEAQERVTVEGLTRHITVSQANALSLPF
                     PDNHFDIVINEAMLTMLNAKAKEKALNEYWRVLKPGGRLLTHDVAYEDPKTRQVLDEL
                     RQTIHVNVAPLSLTGWQALYQEHGFSQVTYHHGKMSLMTPRGMIKDEGLMNTLNIMRR
                     GLKKENRQQFLKMRRFFTRTGKNLCYIAVKSVK"
     gene            complement(4236..5114)
                     /locus_tag="VCR92_001001"
     CDS             complement(4236..5114)
                     /locus_tag="VCR92_001001"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEP4268082.1"
                     /translation="MSERLSGHTLLVSLLATPIRHSLSPKMHNEAYAKLGLDYAYLAF
                     EVGTEQLADAVQGIRALGIRGSNVSMPNKEAILPLLDDLSPAAELVGAVNTVVNKDGK
                     GHLVGHITDGIGALRALADEGVSVKNKIITLAGVGGAGKAIAVQLAFDGAKEIRLFNR
                     QATRLSSVQKLVTKLNQLTRTKVTLQDLEDQTAFKEAIRESHLFIDATSVGMKPLENL
                     SLITDPELIRPDLVVFDIVYSPAETKLLAFARQHGAQKVINGLGMVLYQGAEAFKLIT
                     GQDMPVDAIKPLLGDE"
     gene            complement(5252..8758)
                     /locus_tag="VCR92_001002"
     CDS             complement(5252..8758)
                     /locus_tag="VCR92_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEP4268083.1"
                     /translation="MVYRQKSSEIVTRTITKPSRATSNVKQEIDMTPDSKEQTVTGYQ
                     YHYIDQEGRKQPFNQGWRFLMADVACAQDPSFDDSNWQVIHLPHDFSLTQPYTRNGEA
                     ESAYKLGGVGWYRHYLVLDEVLAGCHVAITFEGSYMETEIYVNGQFIGKHLNGYQEFT
                     YDISDVVTFGAENLLAVRVENKVPSSRWYSGSGLYREVSLSVLPQLHFVADQVAMTLA
                     DTAVQEKGQQKVDLRFALNQSIQTCHYQLSLCLWEQSHCSKDKKLLYQETEVPLADLA
                     FQRQYGLTLSLEELQLWSPDNPHLYDLELTLYYQGQVIDCFCLETGFRQLTFMANQGL
                     FVNGRAVKLKGVCLHHDQGGLGACAYEDALARQLVLLKDMGANTIRSTHNPSSPKLRQ
                     LANRLGFFVIEEAFDTWTYAKNGNVNDFSNYFHQTIGTENASYLQRVRSPETSWAQYS
                     IEAMVWSAKNDPSVLMWSIGNELMEGFSADVSHYPELTRQMCQWIAAIDTSRPITFGD
                     NKLKEADFCWHEEVSQMATLLSQLDHPQGLIGLNYANGKDYDKLHEEHSDWLLYGSET
                     ASAITSRAYYKETKKVLDSGYHLTSYDHAKVDWGAFASQAWYDTITRDFVAGECVWTG
                     FDYLGEPTPWNKIDSGVVGLWPSPKNAYFGILDTAGFPKDSYYFYQSQWAQGQTTLHL
                     LPVWQKDQLCFDEQGLVEVVVYSNAASVQLMFEDEQGNVTDYGRKAFHTYSTPTGHTY
                     QLYQGADAAKNPHENLYLTWRVPYQKGLLRAVAYDISGKSIPKTSGRSQVRTYGSVAK
                     LSWKAFEAPIDAPWELLYLDLSLLDSRGELVSHAQDWLKVQVEGPAHLLALDNGNPTD
                     HTPYQEPLRQAYGGKLLAILALTGEAGHIKVTAKVSQQLSSVFQTQVACRAPKEHLVT
                     LPLEKYQFKKSRLTSQQEIGQSCLKTTQFLSVLENKDTQQKAGKVSTPHILITSYQHY
                     LSLPLQVCSQAFDFKKGDDIFLPQWLQVKDAQGSFVKKAFPMTWYLKEKIFAKPILVT
                     GYVSCFGQSIPVEARLNLAQASKRRHQDLSLVAKQSLATSQKRLTYCYQYDTVQAIGA
                     ISLQNHTDTSLSVSVAISYGSQSSIKQETLMLADSHLSQLEEVIFFDDILTVLYLVVT
                     LEVIEGPDLTEDSIQIGLWDLA"
     gene            complement(8688..10172)
                     /locus_tag="VCR92_001003"
     CDS             complement(8688..10172)
                     /locus_tag="VCR92_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP4268084.1"
                     /translation="MYKVLLVDDEYMILQGLTMIIDWQALGFDVVSTARSGQEALAYL
                     TQYPVDVMISDVTMPGMTGLDLIEAAKTNHPQLQTLILSGYQEFSYVQKAMELETKGY
                     LLKPVDKAELQAKMKQFKDWLDAQQAESIRQETYHDSLLTLWLTDELSEKEFHQLSQD
                     LPEHALTGFTVLYVECSEWIEEMEAYFKQEEQPCYLKKEEDKKIYLAILLGRAQQAKA
                     FTSNLQKQFSENIQQIILGETVDDWENVYESYNQVRQSLFYNSQMSQPTDKGNSKLEM
                     PESRLQFFAFNKALMIGDEPTILAKLEAIFHEMKALNFSPEDVKHVSFLLFSDIYRQF
                     PILDKMTYLSMVKTIHNSQSIDRILRELKKVLDVTNQNNSPEKRYSDLVSETIDCIRK
                     EYHQELTLKAIADRLHVNGVYLGQCFKNETERSFTQYLNHVRIQKAQQLLLYTNQSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGDQ"
     gene            complement(10172..11896)
                     /locus_tag="VCR92_001004"
     CDS             complement(10172..11896)
                     /locus_tag="VCR92_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP4268085.1"
                     /translation="MSVKTLGRYVTNHFKQGFLINRLMKLYSLLIVSFFTLAAIGLSS
                     YSISSTYKRVDAEAQMRLEETLGRLQLQNDITLRVLDQLVGRSEDYHNLYQYMTLTPN
                     QYFSNVFEDWEKGKDTVLFSEEVRRLFDLYPDVTSMTLLLEDSSAYLYADRVIKTGRL
                     LYSKPEKVTGNVLVRSIRNPESGDVTGRLYLTFDKPPTLVETQQDHYLATFAFDYYGR
                     KLFHQGGRRFPHLEAEVKKAIKADRAADLSNLSKAYRMQYNRSGDLLAYVAVRKSYLL
                     AEAVRTVFVYGLVSLLLAWLLLQLLFRVFRNYIQQVSEITDTVEMVAAGDLSLTIDNS
                     HMELELYHISEAINQMLASIKAYIDEVYVLEVEQRDAQMRALQSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFASLLRNNISQDKMTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKIDESIADLAIPKFVIQPLVENYFVHGIDYSRHDNALSIKALDETDHLLIQVLDN
                     GRGISQERLADMEKRLQEHQTTGNSSIGLQNVYLRLFHHFRDRVSWSMAKEPNGGFII
                     QIRIRKDV"
     gene            complement(11886..12491)
                     /locus_tag="VCR92_001005"
     CDS             complement(11886..12491)
                     /locus_tag="VCR92_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEP4268086.1"
                     /translation="MNGIEKTCFLIWKMIQLTLIFHLLSLAGLIVFGVGPAWQTIVTL
                     FLKTPQEENHYSLKRAVQLWKSYFKEANLRFGLFALTFLFLTFNLHWAVQFPSLFWFT
                     VSFLIVIAMVWLTITYLYMVFYAVSYEINLWNNMKLAFISVFLSFKSFLLMLSVLLGI
                     TLMTWQYKGLYLFLTFGALVFCLDFVTKANRRLVDGVIDEC"
     gene            complement(12797..14242)
                     /locus_tag="VCR92_001006"
     CDS             complement(12797..14242)
                     /locus_tag="VCR92_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEP4268087.1"
                     /translation="MKKWQKIVCVTGTVLAASSLAACESKSASKDSDVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATVDLQYIGWGDWDDKMSTIIASGENYDIAFANNYVVN
                     AQKGAFADLTTLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNIKSYADAENVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKTQPFA
                     VKIDEGKPTIINQYEDESFKNNLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSSVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKIGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESVT
                     DDMIAKRDQSIKDAKESPILGFTVDTKVIKTELSNISNVMNRYKASINTGTVDPDEAL
                     PKLLADLKGAGWDKVQKEVQKQLDDFVAKDK"
     gene            complement(14323..15249)
                     /locus_tag="VCR92_001007"
     CDS             complement(14323..15249)
                     /locus_tag="VCR92_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEP4268088.1"
                     /translation="MEKKKKVEKVNVRTFDRKTNAIFNILIGLFAISCIIPFIFVIII
                     SFTDESYLINHGYSFFPDVWSTKAYQYIFQGAMSHRIMRSFGISVFITVVGTFINTTM
                     TSTYAYAISRPYFPYRRFFTVYALITMLFAPGMVANYLVVSNLLHLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGASEWMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSENLYPMQYLLMKIQSNLQALAQNAGMSAQMADSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            complement(15259..16209)
                     /locus_tag="VCR92_001008"
     CDS             complement(15259..16209)
                     /locus_tag="VCR92_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP4268089.1"
                     /translation="MTRQTNKKTSFWKNVIKYRALLLMVLPGFIWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLANFKYLFASKDAWLITRNTIAYNVIFLLFNVFF
                     AIVFAIIMSELRNKRTVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLVGSG
                     ADPIKWYSNPTWWPLILLFMSGWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRNITIPQLLPMMSILLIINIGNIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDIGMASAASLYQSVVGTSILLVTNAIVRRMDPDAALF"
     gene            16405..17283
                     /locus_tag="VCR92_001009"
     CDS             16405..17283
                     /locus_tag="VCR92_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEP4268090.1"
                     /translation="MSLLCIDIGGTSLKFALCHNGQLSQQSSFPTPSSLEKFYQLLDQ
                     EVARYSAYHFSGIAISSPGAINKEKGVIEGASAIPYIHHFKIQEALEERLHYPISIEN
                     DANCAALAEATLGAGKGASSLAMLVLGTGVGGSLVIDGKIYHGAHLFGGEFGFMIMND
                     RYQTFSQLGTVVNMAKRYSAIVNNGKDYTGKAVLALAEQGDHLALKERQVFLQSLAIG
                     IFNIQHAFDPQLILIGGGVSQADFLLSAIEAELDKLYQAVEISDLRPQLAICHFKNEA
                     NLLGAAIDFYQEHKEA"
     gene            complement(17894..19336)
                     /locus_tag="VCR92_001010"
     CDS             complement(17894..19336)
                     /locus_tag="VCR92_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEP4268091.1"
                     /translation="MLAFPKEFWWGGATSGPQSEGRFAKQHRNLFDYWYEEEPDLFYD
                     YVGPDTASDAYHQIESDLALLASLGHNSYRTSIQWTRLIDDFEQVTINPDGLAYYNRV
                     IDACLANGIRPVINLHHFDLPIALYQAYGGWESKHVVDLFVAFSKVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLMQFHYPAIVDGKKAVQVAYNLALATAKVIQAYRQGPAELSDGR
                     IGTILNLTPAYPASQSEADMAAAHFAELWNNDLFMEAAVHGKFPEELVAVLKKDGVLW
                     QSTPEELALIAENRVDYLGLNFYHPKRVKAPDVIPVISPSWSPEWYYDAYLMPGRRMN
                     VDKGWEIYPEAVYDIAIKMRDHYDNIPWFLSENGVGISGEDRYRDETGQIQDDYRIRF
                     LKEHLTYLHKGIEAGSNCFGYHVWTPIDGWSWLNAYKNRYGLVENNIHTQVRRPKASA
                     YWFKKVATHNRLISLEVMEEFGGSASHLSD"
     gene            complement(19361..21055)
                     /locus_tag="VCR92_001011"
     CDS             complement(19361..21055)
                     /locus_tag="VCR92_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase"
                     /protein_id="HEP4268092.1"
                     /translation="MTIYHALKDYQEVMTRGDYLVFDMPLTCRFIGRFFRFENQKALL
                     AELATSKYFQWIEEGQAELTVKHFFNRQLDKDAFTLKVSEDKEIIIESQNLRGFRYAQ
                     EALLKVMTFKGDKLYLPIVSVKHSPSFAMRGIIEGFYGTPWTREERLDCLRFIGRKRM
                     NTYMYAPKDDDYQRKLWRDLYPEDWVTYFKELLAVAKEEGIDFWYMISPGLDFDYTKE
                     ADYQLLYQKLQQLLALGVCHFGLLLDDIDYQIVDAVERRFKKTAYAQAHLATEVHHFL
                     NQQHAAPELVICPTEYDNHHDSIYLQELSERIPKEVAFFWTGPSTLASQISQADIETM
                     AAVYQRPIIIWDNIPVNDYQKDPERLFLTPFANRSPFLCQSDYQVKGIVSNPMISWEL
                     SKLTLTDMSHYLWDANRYQPSNSWLETLTDYTGDAELALALQAFAWHNGNRHLHRDLP
                     FEVEEALLAKDVSTLSAWVDELVERVNTLRKLDKPAFQQAIVPWFERVAKDQDFWQAI
                     LEQGPHLETLYADLQEDKHRIGSDIPSRYYRIYYQQQDKLTANQGQVTQARPEDYA"
     gene            complement(21106..22146)
                     /locus_tag="VCR92_001012"
     CDS             complement(21106..22146)
                     /locus_tag="VCR92_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP4268093.1"
                     /translation="MTKLLYKKIYHFIKEQIASGRLQIGDRLPTEKELSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVAEKQVTSPEANKDLLLILPFTSDYELGDYAKGIM
                     TSIAETGYRLMVQLASTVRLDTLSDYAGIIYYPEDVNHSIDFLFYCDHHHIPLVLLDK
                     SLDLFQFPSVVADNKGGACQLTQHLIEQGCDQISFVATGSFGEVSSVRDRYLGYLAAM
                     AESSLKSHYFPKTETETTDAYLDRLVKTLSETTATKRGLVVENDWLAIQLIQKITQVG
                     LYIPDQVAIVGFDNSQASRLLSPKLSTAAQDFYQMGQEAAKVLLQIIHEPDQAVVSCQ
                     LPVQVFIRESSH"
     gene            22279..23565
                     /locus_tag="VCR92_001013"
     CDS             22279..23565
                     /locus_tag="VCR92_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEP4268094.1"
                     /translation="MTRPIPTSVSQFMAKVESLCGDQHPDWALNFKTSFTNTLETTLK
                     TYEDGTSFLLTGDIPAMWLRDSTAQMKPYLFLAKEDEEIRKIIAGLVKRQFRYICIDP
                     YANAFNEEANGKGHQTDRTQMNPWIWERKYEIDSLCYPIQLAYLLYRETGSTDQFNDD
                     FHRGVELILDLWTVEQDHAQSPYLFERDTWRKEDTLTHAGKGSPVAPTGMTWSGFRPS
                     DDACQYGYLIPSNMFAVVVLSYLEDLYNNLFHNEPVATRAKQLKEAIQSGIADHALVQ
                     NSKGETIYAYEVDGLGQFSIMDDANIPSLLAAPYLGFCAKDDPIYLATRRTILSQENP
                     YYYQGNAAAGIGSSHTPENYIWHIALALQGLTALDQDSKKEMLDLLVATDAGTHLMHE
                     GFDVNDPYQYTREWFSWANMMFCELLLDYLGFSITP"
     gene            23580..26285
                     /locus_tag="VCR92_001014"
     CDS             23580..26285
                     /locus_tag="VCR92_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEP4268095.1"
                     /translation="MATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTDP
                     DFHSFHLDGQTIILDDYLQVRPEREPEIRQAIASGKLRIGPFYILQDDFLTSSESNVR
                     NMLIGKEDCDRWGASVPLGYFPDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEISWQGPDNSRILGLLFANWYSNGNEIPTTEAEARLFWDKKLADAER
                     FASTKHLLMMNGCDHQPVQLDVTKAIALANQLYPDYEFVHSCFEDYLSDLANDLPDNL
                     STVQGEITSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLAAMAYEVTSTYP
                     HDQLRYAWKTLTQNHPHDSICGCSVDSVHREMINRFEKAYEVGHYLAKEAAQQIAGAV
                     NTSDFPTDSQPFLLFNTSGHSKTSVTELTLTWKKYYFGQRFPKEVYQEAQEYLAGLSQ
                     SFQVIDVSGNTISEADILDTSIAFDYDLPKRTFREPYFAIKVRLRLPITLPAMSWKAL
                     ALQLGNETAPSATVPLYDDSNQCLENEFLKVMIQTDGRLTITDKQSGVSYQDLLRFED
                     CGDIGNEYISRQPTHDQPFYADQGTTKLNIISNTAQVAELEIQQTFAIPISADKLLQA
                     EMEAVIDITERQARRSQEKAELTLTTLIRMEKNNPRLQFTTRFDNQMTNHRLRVLFPT
                     HLKTDHHLADSIFETVKRPNHPDATFWKNPSNPQHQECFVSLFDGENGVTIGNYGLNE
                     YEILPDTNTIAITLLRSVGEMGDWGYFPTPEAQCLGKHSLSYSFESITKQTQFASYWR
                     AQEGQVPILVEQTSHHKGSLRAEHSYVTGADDQVALTAFKRRLADNALITRSYNLSND
                     KTCDFSLSLPNYNAKVTNLLEKDSKQSTPSQLGKAEILTLAWKKQ"
     gene            complement(26386..27741)
                     /gene="rocA"
                     /locus_tag="VCR92_001015"
     CDS             complement(26386..27741)
                     /gene="rocA"
                     /locus_tag="VCR92_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RocA"
                     /protein_id="HEP4268096.1"
                     /translation="MLEDFLQFLGFIFLDIIEIMLTLKLFSFVSAIPLRLKNIFYLSL
                     SMVLFQVVFWAFFPDHFILDVVMLAQFLFFALIALYYGKSIKAKFLMFYAFFPLVSIS
                     LVKRFIVFFVMPLFGMPYSVVKHNTLLIYSITCFSIFLIYRCIQVFHFDFSTWRQYFQ
                     SHRASKLLVFTNSSMALYYLCVQGIDVMSPSLSGLATTTARSIIVLFYFILFLTLLIH
                     LERYVKQNSIEAIVQQKEYRELINYSQHLGLLYQDIQELRQLLTTVSSRLKIGIEQND
                     ISIVRLTYEGILNAEKNNAKDDRLDLTCLDKLQVEAIRHIVLAKLIEAKNKKLKVEVS
                     IPNCIATFFLEVVDFTKLLSFLLDNAIEMSLETKQPCLSIAFLDQNHKLVIVIQSSTK
                     QGQNDSQSVFATPALKKRDDWQFDLRNVTTILNRYDYLTISSQIHDGILTQLIEIAKP
                     D"
     gene            complement(28406..29761)
                     /gene="rlmD"
                     /locus_tag="VCR92_001016"
     CDS             complement(28406..29761)
                     /gene="rlmD"
                     /locus_tag="VCR92_001016"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEP4268097.1"
                     /translation="MVVKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIFC
                     QITSVKRNFAEAKLLMVNKASKNRVKPACSVYETCGGCQIMHLAYPKQLDFKDDVIRQ
                     ALKKFKPTGYEQFEIRPTLGMKKPDHYRAKLQFQLRSFGGTVKAGLFSQGSHRLVPID
                     NCLVQDQLTQDIINKITQLVDKYKLPIYNERKIAGIRTIMVRKAQASDQVQIIVVSSK
                     EVRLANFIGELTKAFPQVKTVALNSNRSKSSEIYGDETEILWGQEAIHEEVLDYGFAL
                     SPRAFYQLNPQQTEVLYGEVVKALDVGSKDHIIDAYCGVGSIGFAFAGKVKSVRGMDI
                     IPEAIEDAQKNAKAMGFDNAYYEAGKAEDIIPKWYKQGYRADAIIVDPPRTGLDDKLL
                     KTILHYQPKQMVYVSCNTSTLARDLVQLTKVYDVHYIQSVDMFPHTARTEAVVKLQKR
                     V"
     gene            29876..30652
                     /gene="recX"
                     /locus_tag="VCR92_001017"
     CDS             29876..30652
                     /gene="recX"
                     /locus_tag="VCR92_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEP4268098.1"
                     /translation="MKITKIEKKKRLYLIELDNDDSLYVTEDTIVRFMLSKDKVLDND
                     QLEDMKHFAQLSYGKNLALYFLSFQQRSNKQVADYLRKHEIEEHIIADIITQLQEEQW
                     IDDTKLADTYIRQNQLNGDKGPQVLKQKLLQKGIASHDIDPILSQTDFSQLAQKVSQK
                     LFDKYQEKLPPKALKDKITQALLTKGFSYDLAKHSLNHLNFDQDNQEIEDLLDKELDK
                     QYRKLSRKYDGYTLKQKLYQALYRKGYNSDDINCKLRNYL"
     gene            30732..31265
                     /locus_tag="VCR92_001018"
     CDS             30732..31265
                     /locus_tag="VCR92_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEP4268099.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYMMDTEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEIHKKEMQYSADMDFILKENVKILVDWINHEKGPFS
                     KAYITIWYKRYLELKNR"
     gene            31686..32049
                     /locus_tag="VCR92_001019"
                     /pseudo
     CDS             31686..32049
                     /locus_tag="VCR92_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558053.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         9827 a         7005 c         6058 g         9451 t
ORIGIN      
        1 atttggggca gtattttttt atagctagca agcctttttt aataaaaatg actaagaaca
       61 tagacaatct agggtttact tgctatttca tcttgtttat ggtatcattt cacaggctaa
      121 gggtgcttca tggataacaa cgagattttg tattcctaaa taagacgtta tcccatagag
      181 cacgccatac agaattagta aaggaatcaa acgaatgatt gacattatgt ctgactttca
      241 aaataagact tgttctaaga ataattttat tgttggacct tgttccattg aatcttatga
      301 tcacattaga ttagcagctt caagtgccaa aaaacttggt tacaactatt ttagaggagg
      361 cgcctataaa ccaagaacat ctgctgcttc ttttcaaggc cttggcctgc aaggaattcg
      421 ttacttgcat gaggtttgtc aggaatttgg cttactatcg gtcagtgaaa tcatgtccga
      481 gcgccaatta gaagaagcct atgactatct cgatgtcatt caggttggtg cccgcaacat
      541 gcaaaatttt gaatttttaa aaaccttgtc acacatcgat aagcctattt tgtttaaacg
      601 aggcttgatg gctactatcg aggaatattt gggcgccctt tcctacttac aagacactgg
      661 aaaatctaac attatcttat gcgaacgtgg cgttcgtggc tacgatgtgg agactagaaa
      721 tatgcttgat attatggcag tccctattat tcaacaaaag acagatttac cgattattgt
      781 ggacgtgtct cattcgacag gcagacgaga tttactctta cctgctgcta agatagcgaa
      841 ggctgtcggt gccaatggca tcatgatgga ggttcatcct gatcccgacc atgcgctgtc
      901 agatgctgcc cagcaaattg attataagca attagaacag ttggggcagg aactttggca
      961 agattaagct ctaaatatca ctgcgttatc tctgttacct agtactgatg aaaggagtgc
     1021 ttatgccaca aacacttcat gtccattctc gggtcaagga ttatgatatc ctgtttaccg
     1081 accatgtttt aaaaacctta gcagattgcc ttggtgagcg caagcagcgt aaactcttgt
     1141 ttatcaccga tcaaacggtc taccacttgt atcagactct ctttgaagaa tttgctcagc
     1201 aatacaacgc ttttgtccat gtctgccctc cgggaggtca atccaaatcc ttggaacgtg
     1261 tcagtgctat ctacgaccag ctcatcgctg aaaatttttc caaaaaagat atgattgtta
     1321 ctattggtgg tggtgttgtt ggggatctgg gtggttttgt cgctgcaacc tattaccgtg
     1381 gtattcccta cattcaaatc ccaacgactt tacttagtca ggtggatagc agtatcgggg
     1441 gcaaagttgg agtccatttt aaaggtctaa ccaatatgat tggcagcatt taccctccag
     1501 aagctatcat tatttcaacc acctttttgg agaccttacc gcaacgggaa ttctcctgcg
     1561 gcatcagtga gatgctcaaa atcggcttca ttcatgatag accgcttttt cagcagttac
     1621 gtgattttca aaaagaaacc gataagcagg gacttgaacg tctgatttac caatccattt
     1681 ccaataaaaa acggattgtt gaacaagatg aatttgaaaa tggtttgcgc atgtctttaa
     1741 attttgggca taccttgggc cacgcgattg aatcgctctg tcaccatgat ttttaccatc
     1801 acggtgaagc cattgctatc ggtatggtgg ttgatgctaa actggctgtt tccaaaggac
     1861 tcttgccaaa agaggacttg gatagcctcc ttcaagtttt tgaacgttac cagttaccaa
     1921 caacacttga aagagctgat gtctctgcga catccctctt tgacgtcttt aaaacagata
     1981 agaagaattc tgagcaacat attatcttta tattacccac agaaaccggt tttaccaccc
     2041 tagccattaa caaagacgat caccaatttg tcgagaagct cgacagttta ttataaatag
     2101 tgactccact ctagctagtt aagcttgcta agagaataac ggtatcctgg aactcctaaa
     2161 acatgttact acaagacaag tcttgataac aatataactt ttagctaaga ataactaaca
     2221 gcaacatcaa aaagaggatt tatggaacta taggagaacg gtatcactcg taaaaagatc
     2281 tttcttttgc ctgtcgttca attatttcgt ctaaaaagcc ttaatgagaa acctataagg
     2341 agataggaaa ctcattaagg ttttttagtg aattctaaaa taaaccaagc taaagggctt
     2401 aatctggaga tgagaaggcc aagctttaaa attcgtattg tcatcgcttt gaatacgtaa
     2461 aaagagaaga tgagcgtcat cttctctttt gcttttccat aggccaccca atacagttga
     2521 caataagccc ttaatctaaa agcacttgta atagtttaca atcggtttta gcttctaaat
     2581 gatgggcttt ttgggcaggt atggctatga gactttcttg agttaggacc tgtttttgat
     2641 cctctaaatc gaaaatgagc tgaccttcta aaacaagtat tactttatct cttggactag
     2701 tctcttgact aatgctttct ccttgggcca tggcatataa aacaatagat tgagataatc
     2761 ccagtagacg gctcaaggat cggctagcca cctgatgatc atgatattgc accagttgag
     2821 agagattttc aatcatgtta agcctccggt tttactacta ctaaaagcat ttgaaaggct
     2881 tctactgcat ataaggcatg aggaatagca gctggcatca caatggtttg accttcagca
     2941 acccggtagg tctcttgatc aatggtgatt tctgctaagc cacttaagat agtaaccatg
     3001 gcatctcctg gtgatgagtg tcgcccaatt tcttggccct tatctaagga aaaaactgtt
     3061 attcctaggt cttgcctttg gactagtgtt ctacttaaca tttgatcttg ctcaatcatt
     3121 acttcttgcg tcaaatcaag aaccttcgcg tgctcaatat tattgatata agacatcttc
     3181 gaactcctct atggtctgtt tagttgtatg gacaggttgg tctaaggttt attttacact
     3241 ttttacagca atatagcaga gatttttgcc tgttctggta aaaaaacgac gcatctttaa
     3301 aaactgttgt ctgttctctt tcttaaggcc tcgtctcata atgttcaggg tgttcataag
     3361 accttcatcc ttaatcattc cacgaggtgt catcaaagac attttcccat ggtgataagt
     3421 cacttgagaa aaaccgtgtt cttgatataa ggcttgccaa cctgttagtg acaagggagc
     3481 aacattgaca tgaatcgttt gacgtaactc gtcaagtact tgtcttgttt ttggatcttc
     3541 ataagctacg tcatgtgtca aaagtcgccc gcctggtttt aacacacgcc aatattcatt
     3601 gagtgccttc tccttggctt tggcgttcaa catggttaac atggcttcat taatcacaat
     3661 atcaaaatgg ttatctggaa atggtagtga taaagcattg gcttgggata ctgtaatgtg
     3721 acgggttaac ccctcaacag taaccctttc ttgtgcttct ttgacaacct tggggtttaa
     3781 gtcaacggca tcaatctgac aaccgaaggt tttggctaac tctattgctg tcgtgcagcg
     3841 attgcaggca acctctaaaa cgtgacaatc ctgagagaat tgtccttgtt caatcaacca
     3901 gtttgtcgcc tcaacaccgc caggtcttaa gcgttttttt cctagacgtg ctaaaaagtc
     3961 atgcccaact tcctttgtta ccattgctat tctcctttat tcattgaact tttcctttta
     4021 taagagcttc ttttctaaaa aaacggtagg ttatctggca gacctcaaag gaactatgac
     4081 ttgtatcacg ttagggataa ggctcttcaa ataagctttt tactcttaaa aacagctctc
     4141 gcaaaaagaa ttttagcagc ccatgatgac tgctccatct cttattaata tatcataatt
     4201 aagcttactt aaaaagttct ttaaaaaagg ttgagttact catcacctaa aagaggttta
     4261 atagcgtcaa ctggcatgtc ttgaccagtg attaatttaa aagcttctgc tccttgataa
     4321 agcaccatcc ctagcccatt aatgactttt tgggcgccat gttgacgggc aaaggctagt
     4381 aacttggttt ctgctgggct gtacacgatg tcaaagacca ccaagtctgg gcgaatgagc
     4441 tcggggtcgg taatcaaact tagattttct aaaggcttca ttcctacact tgtagcatca
     4501 ataaatagat gagattccct gatggcctcc ttaaaggcag tctgatcttc caagtcttga
     4561 agggttactt tagtccttgt tagctggttc agttttgtca caagcttttg aacgctactt
     4621 agacgtgtag cttgtcggtt aaacaaacga atctctttgg cgccgtcaaa agcgagctgg
     4681 acagcgatag ctttcccagc cccaccaact cctgctaggg taatgatttt gttctttacc
     4741 gacactcctt cgtcagccaa ggctctgagc gctcctatgc cgtctgtaat atgccccacg
     4801 agatgtcctt taccatcctt attgacaacc gtattgactg caccgaccaa ctcagcagct
     4861 ggggacaagt catccaataa gggtaaaata gcttctttat ttggcataga cacattggag
     4921 ccacgaattc ctaaggcacg aatcccttgc acggcatctg ctaattgctc tgtccctact
     4981 tcaaaagcaa ggtaggcata atccagcccc agtttagcat aggcttcatt gtgcattttg
     5041 ggagacaaac tatgacgaat aggagtagca agcaaagaga ccagcagggt gtggcctgat
     5101 aaacgttctg acatttagaa atctcacttt ccatttcaac cttgtaaagg cgcctttcac
     5161 gtaataaagg acgcctattt gttttttatt ataccttatt ttacaaaatt tatcagacct
     5221 ggtgccaaag aagtcttctt ttacttatgc ttcatgctaa atcccaaagg ccaatttgaa
     5281 tactgtcttc agttaggtca ggtccttcaa tgacttcaag ggtcactact agatacaaaa
     5341 cagtcaaaat atcatcgaag aaaataacct cttctaactg gctcaagtgg ctatcagcta
     5401 gcatcaaggt ttcttgctta atagagctct gactaccata actgattgcc acagaaacac
     5461 taagagatgt gtctgtgtga ttttgcaagc taatggctcc tatggcttgc accgtatcat
     5521 attggtagca ataagttagc cttttttgac ttgtggccag ggattgcttg gcgactaaac
     5581 tgagatcctg gtgccgtctt ttgctagctt gtgctaggtt aagccttgcc tcaaccggta
     5641 ttgattgccc aaaacaagaa acatagcccg tgacaagaat aggcttggca aagattttct
     5701 cttttaggta ccatgtcatt ggaaaagctt ttttcacaaa agaaccttgg gcatctttga
     5761 cttggagcca ctgaggcaag aagatatcgt cgcctttttt aaaatcaaat gcctgagaac
     5821 aaacctgcaa gggcagagat aaatagtgct ggtaactggt gataagaatg tgaggtgtgc
     5881 taaccttacc tgctttttgc tgggtgtctt tgttctccaa aacagaaagg aattgtgtgg
     5941 tctttagaca agattgacca atttcttgtt gacttgtcag tcggctcttt ttaaactgat
     6001 atttctctaa aggtagtgtc actaagtgtt ctttgggggc acggcaggct acttgtgtct
     6061 gaaaaacact gctaagttgc tgcgagactt ttgccgtgac cttaatgtgt cccgcctctc
     6121 cagtgagggc taaaatggct aataattttc ccccatatgc ctggcgtaga ggctcctgat
     6181 aaggggtgtg gtcagtcgga ttcccattat caagagccaa caaatgggct ggtccttcta
     6241 cttgaacctt tagccaatct tgagcatggc tgaccaattc acctcggcta tccaagagtg
     6301 ataaatccag ataaagcaat tcccaaggag cgtcaatagg tgcttcaaag gctttccaag
     6361 atagctttgc cactgaacca taggttctaa cctgagaacg tccactggtt tttggaatgc
     6421 ttttaccaga aatgtcgtag gccactgccc ttagcaaccc tttttgatag ggcactcgcc
     6481 aagtcaggta aagattctcg tgaggattct tagcagcgtc agctccttgg taaagctgat
     6541 aagtgtgtcc cgttggcgtg ctataagtat gaaatgcctt ccttccataa tctgttacgt
     6601 tgccctgctc atcttcaaac atcagttgaa cactggcagc attgctataa accacaacct
     6661 ccaccaatcc ctgctcatcg aaacaaagct ggtccttctg ccagactggt aacaggtgca
     6721 aggtggtctg cccctgcgcc cactgacttt ggtaaaaata atagctatct tttggaaagc
     6781 ctgccgtgtc taaaatgcca aagtaggcat ttttaggaga aggccaaagg cctacaacac
     6841 cgctgtcgat cttgttccag ggtgtaggtt ctcctaaata atcaaagcct gtccaaacgc
     6901 attcgccagc aacaaaatca cgggtaatgg tatcatacca agcctggcta gcgaatgcac
     6961 cccaatcgac cttagcatga tcataagagg ttaggtgata accggagtca agaacttttt
     7021 ttgtctcttt ataataagcc ctgctggtaa tggctgaggc tgtttcagaa ccatacaaca
     7081 gccaatcaga gtgctcctca tgaagcttat catagtcttt tccattagca tagtttaacc
     7141 caatgagtcc ctggggatgg tctaattgac taagaagagt tgccatttgc gacacttcct
     7201 catgccagca aaagtcagct tcttttaatt tattgtcccc aaaggtaatg ggacgtgagg
     7261 tgtcaatagc agcaatccat tggcacattt gtcttgttag ctctgggtaa tgactgacat
     7321 cggctgaaaa accttccatc aattcattcc caatcgacca catcaacact gacgggtcat
     7381 tcttggcaga ccagaccatg gcctcaatac tatactgggc ccagctcgtt tcaggtgacc
     7441 tcactctttg aagatagctt gcattttcag ttccgatggt ctgatggaaa tagtttgaaa
     7501 agtcattaac atttccattt ttggcatagg tccaggtgtc aaaggcttct tcaatcacaa
     7561 aaaagccgag acgattggct agttgcctaa gtttgggact acttgggtta tgggtgctac
     7621 gaatggtatt agcccccatg tctttcaaca ggactaattg tctggctagg gcatcttcgt
     7681 aagcacaagc tcctaggcct ccttggtcat gatgcaaaca aactcccttt aatttgacag
     7741 ctctgccatt cacaaaaagc ccctgattgg ccataaaagt cagctgacga aaaccagttt
     7801 caaggcaaaa gcaatcaatg acctgacctt gatagtaaag agtgagttct aaatcgtaga
     7861 ggtgaggatt atctggtgac cacaattgga gttcttccaa agacagtgta agaccatact
     7921 gtctttggaa agccaaatca gctagaggca cttctgtttc ttgataaagg agtttcttgt
     7981 cttttgagca atgtgattgt tcccataaac agaggctcaa ttggtagtgg caagtctgaa
     8041 tagactgatt gagggcaaag cgtaaatcaa ctttctgttg ccctttctcc tgcacagcag
     8101 tatcagccaa ggtcattgct acctggtctg ccacaaaatg aagctgggga agaacagaca
     8161 aactcacttc acgataaaga ccactgcctg aataccaacg agaactggga accttgtttt
     8221 caacccggac agccagaaga ttttcagctc caaaagtcac aacatcagag atatcataag
     8281 taaattcctg atagccattt aagtgtttgc caatgaattg cccgttaaca taaatttccg
     8341 tttccatata ggaaccctca aaagtaatgg caacatgaca accagctaaa acctcatcta
     8401 acacgagata atgccgatac caaccgacac cacctaattt ataagcactt tcagcttcac
     8461 catttcttgt gtaaggctgc gtaagactga aatcatgtgg taaatgaatc acctgccagt
     8521 tcgaatcatc aaaagaaggg tcctgagcac acgccacatc tgccataaga aaacgccagc
     8581 cttgattaaa gggctgcttt cttccttctt gatcaatata gtggtattgg tagccagtca
     8641 ctgtctgctc cttgctatct ggtgtcatat caatctcctg tttgacgtta ctggtcgccc
     8701 ttgatggctt ggtaattgtc cttgtaacga tctctgaact cttttggcga taaaccattc
     8761 aactttttaa acatcttgat aaaataatga ttggtattgt aacctgtttc ataagcaatt
     8821 tcattgatgg attggttggt gtaaagcaat aactgttgcg ctttttgaat cctaacatga
     8881 tttaagtact gggtaaaact acgctcggtt tcatttttaa agcattgccc taaataaacc
     8941 ccattgacat gtaacctatc agcgatagct ttaagggtta attcttgatg gtattccttg
     9001 cgaatgcaat caatggtttc actaactaaa tctgaataac gtttttcagg ggaattgttc
     9061 tgattggtga catccaacac tttttttagt tccctcaaaa tgcgatcaat ggattggctg
     9121 ttatgaatag tttttaccat ggacagataa gtcattttat ctaaaatggg aaattgacgg
     9181 taaatgtcag agaacaacaa gaacgacaca tgcttcacat cctctggtga gaagttcaag
     9241 gccttcattt catgaaaaat ggcttctaat ttggccaaga tggttggctc atcaccaatc
     9301 atcaatgctt tgttaaaggc aaaaaattgc aaccgagatt ctggcatctc aagcttactg
     9361 ttgcctttgt cagttggttg tgacatttgg ctattgtaaa aaagactctg gcgcacctga
     9421 ttgtagctct cataaacatt ttcccagtca tcaaccgttt ctcctaggat gatttgttgg
     9481 atgttctctg aaaattgctt ttgtagatta ctggtaaagg ctttggcttg ctgggctctc
     9541 ccaagtaaaa tcgccaagta aatcttcttg tcttcttctt ttttgaggta acagggttgt
     9601 tcttcttgct taaaataagc ctccatctct tctatccact cggaacactc cacatacagc
     9661 acggtaaatc ctgttagggc atgctcgggg agatcctggc taagttgatg aaattctttt
     9721 tcactaagtt catctgttaa ccacagtgtc agaaggctgt catgataggt ttcttgccgg
     9781 attgattcag cctgctgggc atccaaccag tctttaaatt gtttcatttt agcctgcaat
     9841 tctgccttat ccacaggttt tagcaaatac cccttggttt ctaattccat agccttttgc
     9901 acataggaga attcttgata accagataaa atcaaggttt gtagctgagg atgattagtt
     9961 ttagctgctt ctattaaatc cagtcctgtc attccaggca tggtaacatc tgaaatcatg
    10021 acatccactg ggtactgagt caaataggct aaggcttcct ggcctgatct tgctgttgaa
    10081 acgacgtcaa aaccaagagc ctgccaatca ataatcatgg ttaatccttg tagaatcatg
    10141 tattcatcgt caactaataa taccttatac attaaacatc ctttctaatc ctaatttgaa
    10201 tgataaagcc accatttggc tccttagcca tggaccaaga aaccctgtct cgaaaatgat
    10261 ggaaaagacg gaggtaaaca ttttgcaaac caatagagct attgcctgtt gtttggtgct
    10321 cttgaagcct tttttccata tctgctaagc gctcttgact aataccacgt ccattatcaa
    10381 gcacctgaat caagagatga tccgtctcat ctaatgcctt gatgcttagt gcattgtcat
    10441 ggcgactata atcaatccca tgcacaaaat aattttcaac gagaggttga atgacaaatt
    10501 taggaatggc taaatcagca atactctcat caatttttac atgataagcg aagctatctg
    10561 gataccgcat ttggtagagg taaatgtact tttcacaaaa agccagttct tcttttaagg
    10621 tggtcatctt atcttggcta atattgttgc gaagcaaact cgcaaaggca taaatgacat
    10681 ctgctaattc ttcttgttga caactaaggg cgtacatccg aatatactct aacgtgttgt
    10741 ataaaaaatg agggttgatt tgagactgca gagctctcat ttgggcatct cgttgctcta
    10801 cctctaacac ataaacttcg tcaatataag ctttaatgct ggccaacatc tgattaatgg
    10861 cttctgagat atgatacagt tccaattcca tgtggctgtt gtcgatggtt aaagacaaat
    10921 cgcctgctgc aaccatttca acagtatccg taatttcaga aacctgctgg atataatttc
    10981 ggaaaaccct aaagagcaac tgcaataaca gccaagctaa gagtagagaa acaaggccat
    11041 acacaaaaac tgtcctgaca gcttccgcta ataaatagga ttttctgaca gccacataag
    11101 ctaagaggtc tcccgagcga ttgtactgca tccgataagc cttgctgaga ttactaagat
    11161 cagctgcccg atctgccttg atagcctttt taacctcagc ctctaaatga ggaaatctcc
    11221 gacctccttg atggaagagt ttgcggccat agtaatcaaa agcaaaagta gctaaatagt
    11281 gatcctgctg tgtctctacc aaagtcggtg gtttgtcaaa ggtcaggtaa agacgacctg
    11341 tcacatctcc tgattctgga tttcgaatgg agcgaactaa aacatttccg gttacttttt
    11401 caggcttgct ataaagcaaa cgacccgtct taatgaccct atcggcgtac agataagcac
    11461 tactgtcctc tagcagtagg gtcatagaag tcacatcagg gtacaagtca aaaagacgcc
    11521 tcacctcttc agaaaatagg accgtgtctt ttcctttttc ccagtcttca aaaacgtttg
    11581 aaaaatattg gtttggggtt aacgtcatat attgatagag gttatggtaa tcttctgaac
    11641 ggccaaccaa ctggtctaaa acccgtaggg taatatcgtt ttgtaactgc aatctaccta
    11701 gagtctcctc cagtcgcatc tgcgcctcag catccaccct tttataagta ctactaatag
    11761 aataactgct caagccaata gctgctaaag tgaaaaaact tacaattagc aggctatata
    11821 atttcatcag tcgattaatc aaaaaaccct gcttaaagtg gttagtcaca taccttccca
    11881 atgttttaac actcatcaat cactccatct actagtcgac gattagcctt agtgacaaag
    11941 tccaagcaaa agactagagc tccgaaggtt aaaaagagat aaaggccttt gtattgccaa
    12001 gtcattaagg taattcccag caaaacactc agcatgagta aaaaggattt gaaacttaaa
    12061 aagacgctga taaaggctaa tttcatatta ttccaaaggt taatctcata gctcactgca
    12121 taaaaaacca tgtaaagata ggtaatggtt agccaaacca tggctattac aatcaagaaa
    12181 gacacggtaa accaaaacaa ggatggaaac tgtactgccc aatgcaaatt aaaggttaaa
    12241 aaaaggaaag tcagggcaaa aagaccaaat cttagattag cttctttgaa ataagatttc
    12301 caaagttgaa cagccctttt caaagaatag tggttttctt cttgaggtgt ttttaaaaat
    12361 agggtgacaa tggtttgcca ggctggcccc accccaaaca caatcagtcc agctaaggac
    12421 aagagatgaa aaatgagggt caattggatc attttccaaa ttaaaaagca ggttttttca
    12481 atgccattca tatgatagtc ctctttttct tgttaacact tatagcggtt tcaaggacca
    12541 gcagctacga gactagtttt agcaccccca gtaagatgct ggtattagtt ttactctgat
    12601 taatagttta gactcttcta atatagcaca ctttataggc ttttggaaac cgctttacta
    12661 agagtagtaa cattatttac attaattttt ctccctttat aacttccact tatttgatga
    12721 tccgtttttt ccactcatca gaagaaaaga gctgagattt cccagccctc aacttataat
    12781 caagaaaatg aatgccttac ttgtctttag ctacaaagtc gtccaattgt ttttgaactt
    12841 ctttttgcac cttgtcccaa ccagcacctt tgaggtctgc aagaagtttt ggaagggctt
    12901 cgtcaggatc cactgtacca gtattgatac ttgctttata tcggttcatg acatttgaaa
    12961 tatttgataa ttccgttttg ataacttttg tgtcaacagt gaaaccaagg attggagatt
    13021 ctttagcatc cttgattgat tggtcacgtt tagcaatcat gtcgtcagta acagattctt
    13081 gagtgtaaag gattttattg ttaccagtat tccaagcacc catgtgcatt tttggttgat
    13141 agccatcgag cagtttgatt ttcttgtcgc caattttttc ccaagctttg ccttcgacac
    13201 cataaacaag cccatttaac aattcgggat cgctattaag aagagaaagg acttcaactg
    13261 ctttttcttt gtttttagat acgcttgata ccacaaagtt tgccatttgt gcttgtgatg
    13321 tggtttttag cggtttagtc aatggacgag acacgatgtc ttttcctgca gcattggtca
    13381 agatagtatc gccatagtcc ataggacctt gggtttcttc acgcataaac caagtgtttc
    13441 cttcaagggg ataaccttct gtattggtcg ctgcatctgt tggaatcaaa ccttctttat
    13501 accatttgtg catcaagcgg agattgtttt taaaggactc atcttcatac tgattaatga
    13561 tggttggctt gccttcatca attttcacag caaagggttg ggttttggtt aatgggtagt
    13621 catagtcacc tgacatacta aagacttgac caatagcaaa agctgctgta tttggttctt
    13681 tttcgtggaa ttgtttcaag acattttcag catctgcata ggacttaatg tttgaaatgt
    13741 caaggccata tttgtccact agttctttat tgaaagaaag catctgttgg gcataaacgt
    13801 tggcatctac tgggaaggca tagagtttac cgtcaatagt atttccttta atataggctg
    13861 ggtctaagtt tttatacgtt ttcttagcgt attttggcat taacgttgtc aaatcagcaa
    13921 aagcaccttt ttgtgcattg accacataat tattggcaaa agcaatgtca tagttttcac
    13981 cagaggcaat gatggtactc attttatcat cccagtcccc ccaaccgatg tattgaaggt
    14041 caaccgttgc acctgttttt tctttgatgc gcttgttagc aattgtcatc aattcatcga
    14101 agttatcagg tttgtcacca acttggtaca tcaataattt gacatcacta tcctttgatg
    14161 ctgacttgct ttcgcaggct gctaaactag acgctgcaag cacagttcca gtcacacaca
    14221 cgattttttg ccactttttc ataagtgaag cctcctaaaa aatgttttct tttgttacta
    14281 atgattagat aaaatctggt cttgtgacca gttccttaag tcctattcct tcaccccacc
    14341 aatggtcaaa ccaccgacaa agtacttttg gaagaatggg taagtcaagg caatcggcaa
    14401 ggttgcaata accacgatag ccatacgaac tgattctttt ggcagcgatg ctaagctatc
    14461 tgccatttgt gcactcatgc cagcattttg tgccaaggcc tgtaggttgc tctgaatttt
    14521 catcagtaag tactgcattg ggtagaggtt ttcactttgc acataaagca aggcgttaaa
    14581 ccaatcattc caataagtta aggcagaaaa taaactgatg gtagcaatcc ctggaacagc
    14641 caaagggaga acaattttca taaaaatcat ccattcacta gccccatcca tacgagccga
    14701 ctcaataatg ctatctggaa ctgtcttttt aaagaacgtt ctcatgacca agatgccaaa
    14761 tgggcccaga gccattggta aaatcaaagc ccaaaccgta tccttcaaat gaaggagatt
    14821 actgaccacc aagtaattag caaccatccc tggtgcaaag agcatggtga taagtgcata
    14881 aacagtaaaa aaacgtctgt atgggaaata aggtcttgaa atcgcataag cataggttga
    14941 tgtcatggtc gtgttaataa aggttcccac cactgtaata aacacggata tcccaaatga
    15001 cctcatgatt ctatgggaca tggctccttg aaaaatatac tggtaagcct tagttgacca
    15061 gacatctgga aaaaaactat acccatgatt aatcaagtaa ctttcatcag tgaaggaaat
    15121 aataatcacg aagataaaag gaatgataca agagatggca aacagaccaa tcagaatatt
    15181 aaagatagca ttggtttttc gatcaaaggt tctaacatta accttttcga cttttttctt
    15241 tttctccatg ttttcctcct aaaacaaggc tgcatcagga tccatgcgac gaacaatcgc
    15301 attagtgact aacaagatgc tggtcccaac tactgactga taaaggctag ctgccgatgc
    15361 catcccaata tctcctgtag cagtcaaggc attgtagaca taggtatcta acacactggt
    15421 cacgtcataa agtgggcctg aattcttggg aataacgtag aaaagtccga aatcagattt
    15481 aaaaatatta ccaatattaa tgatcaataa gatagacatc attggcaata attgtggaat
    15541 ggtgatgttc ctaatttgtt gccatttgct tgcaccatcc accatagcag cttcataata
    15601 agtatcagaa atccctttga ctgaagcata gtagataatg ctattgtagc ctagcccttt
    15661 ccagccactc ataaagagta aaatcaaggg ccaccaagtg ggattggaat accacttaat
    15721 tggatctgct ccactgccaa ccaagagctg attaatgaaa cctttatctg tatttaaaaa
    15781 ggcagaaaca aagtattcaa taaccaccca tgataagaaa taaggcaaca aggacatggt
    15841 gtgatagacc ttaaccgttc gcttatttcg taactcactc atgataatgg caaaaacaat
    15901 cgcaaagaaa acattaaaaa gtaagaaaat cacattgtaa gcgatggtat ttctggtaat
    15961 caaccaagca tctttggaag caaagagata tttgaaatta gccaaaccaa cccaagggct
    16021 ctccttcaaa ctttccataa agccccctgc tgaataatga aaatctttaa aagcaaccac
    16081 attggctaaa actggaatat aaaagaaaaa gatgaaccag atgaaacctg gtaataccat
    16141 taataataag gcccggtatt taatcacatt tttccaaaag gatgtctttt tgttggtttg
    16201 tcttgtcatt tcccaacctc cctttgtgtt aatcacgtta tagttacagt atatcaagcg
    16261 ctttcattat tttaaagcaa caaattatag gtatgataac acaaagtata gaatcactta
    16321 gaaagccttt tcattgttgc ttaaatctgt catactaaga tgagacatga tcgtctattc
    16381 tactataata aaggagaaca cctcatgagc ttgttatgta ttgatatagg aggcacttcc
    16441 cttaaatttg ccctctgtca caatggccaa ttaagccagc aaagcagctt tcccactccc
    16501 tctagtctgg aaaagtttta ccaattactc gaccaagaag ttgctcgtta ctctgcttac
    16561 catttctcag gtattgccat cagttcacct ggggcaatca ataaagaaaa gggggttatc
    16621 gaaggcgcca gcgctattcc ctacattcac cattttaaaa tacaagaggc cttagaagaa
    16681 cggctacatt accctatttc tatcgaaaat gatgccaatt gtgccgcctt agctgaagct
    16741 accttagggg caggaaaagg cgctagtagc ctagccatgc tcgttcttgg tactggagtt
    16801 ggaggaagct tggtcattga tggcaagatt taccatggtg cccacttatt tgggggcgaa
    16861 tttggtttca tgatcatgaa cgaccgctac caaaccttta gtcagttagg gacagtggta
    16921 aatatggcca agcgctatag tgcaatcgtc aataacggaa aagattatac tggcaaagct
    16981 gtccttgccc tcgcagaaca aggagaccac ctagcactca aagaaaggca ggtctttctc
    17041 caaagtttag ccatcggtat ttttaacatt caacacgcct ttgatcctca actgatttta
    17101 atcgggggtg gtgtttccca agctgacttt ctactgtcag cgattgaagc tgaactagac
    17161 aaactctacc aagccgtcga aatctccgac cttagacccc aattagctat ttgtcacttt
    17221 aaaaacgaag ccaatcttct tggagctgcc attgattttt accaagaaca caaggaggcc
    17281 taaccatgga ccgctaaatc cctcttatcc cctattgtcc ctaatcgcct ctgacatcta
    17341 caaagacatc ctaaaaggat tgctgattag ctacaacgat actcgctttc tgcctaaatg
    17401 actctctgct gatgaacaca gcctgatgcc tggtcccttt gttgatgtca ttgttgctga
    17461 cgcttctgtt aaaggcattg gtcatcagtt aatactcgag ctattagaag ctatgctagt
    17521 tatcgccaat aagcaaagcc tcacttaata actcactcat atagtcccct tatcgtggac
    17581 agtgacataa caaacagtca ctagaaacca tgaggggctt ttatctggtc caaaaatatg
    17641 aaagaaaatc ctaaaatacc aagatgaaaa acaagcatcc ttagccaaga tactctaaag
    17701 aattgaagag ccaaattacc caagatggat agatgatgcc aaaccagaca gaacgcttat
    17761 atctagttcg gcaaatacca acaccttcca aagaaataca agagcctcga tcctcttaac
    17821 atgaggaaaa aggcccttgt ttaatcattg gtaacatcat tattcacttg tctcaaagga
    17881 gacgttcaca cgttcaatca ctgaggtgag aagcagagcc tccaaactcc tccattactt
    17941 ctaatgaaat caagcggtta tgagtagcta cttttttaaa ccaataagct gaagctttag
    18001 gtcgtcgcac ttgggtatgg atattatttt ccacaaggcc atagcggttt ttataggcat
    18061 tgagccaaga ccagccatca attggcgtcc atacatggta tccaaaacaa ttcgagcctg
    18121 cttctattcc tttgtggagg taggtcaaat gttctttcaa aaatcggatg cgataatcat
    18181 cttgaatctg accagtttca tcacggtaac ggtcttctcc tgaaatccct acaccatttt
    18241 cagataagaa ccaaggaata ttgtcgtaat ggtctcgcat cttgatggca atatcataga
    18301 cagcctcagg atagatttcc caccccttat ccacgttcat gcggcggcca ggcatcaggt
    18361 aggcgtcata ataccattca ggactccaag atgggctaat cactggaatg acatccggag
    18421 ccttcacgcg cttagggtgg taaaaattca atcccaaata atccactcta ttctcagcaa
    18481 taagagccaa ttcttctggc gttgactgcc acaaaacccc atcttttttc aataccgcaa
    18541 ccaattcttc tgggaatttc ccatgaacag cagcttccat aaacaagtca ttgttccaaa
    18601 gttctgcaaa atgcgcagca gccatgtccg cttctgattg actagctggg taggctggcg
    18661 tcagattgag aatggttcca atacgcccat cactaagttc tgctggacct tgcctgtaag
    18721 cttgaataac cttggctgtg gctagggcta ggttataggc gacctggact gcttttttcc
    18781 catccacgat agcagggtaa tgaaattgca ttaaataaga gccttccaca acgaccatag
    18841 gttcattgtg gacaaaccaa tccttaaccc gatcaccaaa ctgctcaaaa caaaccttgc
    18901 taaaggcgac aaataagtcc acgacatgct ttgattccca gccaccatag gcttgataga
    18961 gggcaatggg caggtcaaaa tgatgcaaat taatgacagg acgaatacca ttggccaagc
    19021 aagcatcaat cactcgatta taataagcaa ggccatcagg attaatcgtc acttgctcaa
    19081 agtcatcaat caaacgcgtc cactgaatgg aggtgcggta ggaattgtga cctagtgaag
    19141 ctaacaaggc caaatcagat tcaatctgat gataggcatc cgaagccgta tcaggtccca
    19201 cgtaatcgta aaacaagtca ggctcctctt cataccaata atcaaagaga ttgcggtgct
    19261 gtttagcaaa tcgcccctca ctttgagggc ctgaagtggc tcctccccac caaaactctt
    19321 ttggaaatgc taacatatca ttcctttcta gctcgtatga ctaagcataa tcttcaggtc
    19381 ttgcttgggt aacttgacct tgattagctg ttagtttatc ttgctgttga tagtagatgc
    19441 gatagtagcg acttggaatg tcacttccaa tacggtgttt atcttcttgt aagtcagcat
    19501 agagtgtttc caaatgaggc ccctgctcta aaatggcctg ccaaaaatct tggtctttgg
    19561 ccacacgttc aaaccaagga acaatagctt gttgaaacgc tggcttatct agctttctca
    19621 acgtattgac acgttctacc aattcatcta cccaagctga taacgttgat acatccttag
    19681 ccaggagagc ttcttccact tcaaaaggaa ggtccctgtg cagatgacga ttgccattat
    19741 gccaagcaaa tgcctgtaaa gctaaggcta attcagcatc tcctgtatag tctgttaagg
    19801 tttctagcca agagttacta ggctgataac ggttagcatc ccacagataa tggctcatgt
    19861 ctgtcaaggt cagcttagat aattcccaac taatcatagg gttagaaaca atccccttga
    19921 cctgatagtc tgattggcat aaaaatggtg agcgattagc aaaaggggtt aaaaagagac
    19981 gttctggatc tttttgataa tcattaacag gaatattgtc ccaaataatg ataggccgct
    20041 gatatactgc tgccatggtt tcgatatctg cttgcgagat ttgactcgct agcgtgcttg
    20101 ggcctgtcca gaaaaaggcg acttctttag gaatcctttc tgacagctct tgcaaataga
    20161 tagaatcatg gtggttgtcg tattctgtcg gacagatcac caattctggc gccgcatgtt
    20221 gttggtttaa aaagtgatga acctcagttg ccaagtgggc ctgggcatag gcagtctttt
    20281 tgaatcgtct ctcaacagca tctacaattt ggtagtcaat atcatccagc aaaagcccaa
    20341 aatgacaaac acctaacgct agaagttgtt gcaatttttg atagagcaac tgatagtcag
    20401 cttccttggt ataatcaaaa tcaagtcccg gactaatcat ataccaaaaa tcaatccctt
    20461 cttccttggc tactgcaagt agctctttga aataagtcac ccaatcctca ggataaagat
    20521 cgcgccacag ttttcgctgg taatcatcat ctttcggagc atacatgtaa gtattcatcc
    20581 ttttacgtcc aatgaaacgc aggcaatcta accgctcttc tcgtgtccac ggtgttccgt
    20641 aaaagccttc aattatcccc cgcatagcaa aagaaggact atgcttgaca gatacaatcg
    20701 gtaaataaag tttatcccct ttgaaagtca tcactttaag caaagcttct tgggcgtaac
    20761 gaaaacctct aaggttttgg ctttcaataa taatttcctt atcttctgaa accttcaggg
    20821 taaaggcatc cttatccagc tgacggttaa agaaatgttt aacggtcaac tctgcttggc
    20881 cttcttcaat ccactgaaaa tactttgacg ttgccaattc tgccagtagg gctttttgat
    20941 tttcaaaacg gaaaaaacgg ccaataaagc ggcatgtcaa cggcatgtca aagacaagat
    21001 agtctcctct tgtcatgact tcttgataat cctttaaggc gtgataaatg gtcatttctg
    21061 gtctccttta cctgagctaa ccagctcatg ctagtaacgt cttttttagt gactactttc
    21121 tctgataaat acttgaacag gtaactggca agacaccact gcttggtctg gctcatgaat
    21181 aatctgcaac aagactttag ctgcttcttg ccccatttgg taaaaatctt gagctgctgt
    21241 gcttaatttg ggactcaaca aacgggaggc ttgactatta tcaaagccta caatagcgac
    21301 ttgatcagga atatataagc ctacctgtgt gattttttga atcagctgaa tagccaacca
    21361 atcgttttcc acgacaagcc cccttttagt ggctgtcgtc tccgataagg ttttcaccag
    21421 acggtccaaa taagcatctg ttgtttcagt ctctgtctta ggaaaataat gggattttag
    21481 agacgattct gccattgccg ctaagtaacc caaataacgg tctctaacgg atgatacttc
    21541 tccaaaagag cctgttgcca caaaactaat ctggtcacag ccttgctcaa tcaagtgctg
    21601 agtcaattga caggcaccgc ctttattatc cgctacaaca gacggaaact gaaaaagatc
    21661 tagagattta tccaacaaga ctagaggaat gtgatgatgg tcgcagtaaa acaggaaatc
    21721 aatactgtga ttgacatctt caggataata aataatccca gcatagtctg acagggtgtc
    21781 taaccttact gtactggcca attgaaccat gagacggtaa cctgtttcag caatggaggt
    21841 cataattccc ttagcataat ctcccaattc ataatcagaa gtaaaaggaa gaatcaacaa
    21901 taaatcctta ttcgcttcag gggacgtcac ttgcttttca gctacgaagc ttcctttccc
    21961 acgacttctc gtaatcaagc cttcttgctc cagttctaca agcgctcgct tagaagtaat
    22021 acggctaacc gagaactgtt ctgacaattc tttttcagta ggtaggcggt caccaatttg
    22081 caaacgacct gatgctatct gctctttaat gaaatgatat atctttttgt ataataattt
    22141 tgtcattctt tactcccgtt atcagtatag catgtcaaaa aagagttgta aaccttttca
    22201 aaaacttata gacaaagttt aacttatcat ttataatgaa accgaagata aatgatatat
    22261 cattttggag gatatgatat gacacgacca atcccaacta gcgtcagcca atttatggcc
    22321 aaggtggaaa gcctttgtgg agaccaacac cctgattggg ctcttaattt caaaaccagc
    22381 tttaccaata ccttagagac aaccctaaaa acctacgaag atggcactag ctttctcttg
    22441 acaggagata ttcctgccat gtggttacgt gattccactg cgcaaatgaa accttacctc
    22501 ttcctcgcca aggaagatga agaaattaga aagattattg ccggtttggt caaacgccaa
    22561 ttccgctaca tttgtatcga tccctatgcc aatgccttca acgaagaagc taacggaaaa
    22621 ggacaccaaa cagatcgtac ccaaatgaac ccttggattt gggaacgcaa atatgagatt
    22681 gattccctct gctaccctat tcagctagct tacttgctct atcgtgaaac aggaagcacc
    22741 gatcagttta atgacgattt tcatcgtggg gtagaactca ttcttgacct atggacagtt
    22801 gagcaagacc acgcccagtc tccttacttg tttgaacgcg atacttggcg caaagaagat
    22861 accctaacac atgctggaaa aggaagtcct gtcgcaccaa cagggatgac ctggtcaggc
    22921 tttagaccaa gtgatgatgc ttgtcaatat ggttacctca ttccttcaaa tatgtttgca
    22981 gtggttgtgc tttcctatct agaagattta tataacaacc tttttcacaa tgaaccagta
    23041 gctactcgtg ccaagcagct gaaagaagct attcaatcgg gtattgcaga ccatgccctt
    23101 gttcaaaaca gcaagggaga aaccatttac gcttatgaag tggatggtct gggacagttt
    23161 tccatcatgg atgatgctaa tattccaagc ctccttgctg caccttacct tggtttttgc
    23221 gctaaagatg accctatcta tctggcaacg cgccgcacca ttctcagcca agaaaatcct
    23281 tattattatc agggaaatgc agcagcaggc atcggttctt cccatacacc agaaaattat
    23341 atctggcata tcgcccttgc cttacaagga ttgaccgctc ttgaccaaga cagtaaaaaa
    23401 gagatgcttg atttgcttgt ggcaacagat gctggtaccc acttaatgca cgagggtttc
    23461 gatgtcaatg atccttatca atacactcgt gagtggttct cttgggctaa catgatgttt
    23521 tgtgaactac ttcttgacta tcttggcttt agcattactc cttagaaagt gaggccacta
    23581 tggcaactaa aaaagtacat attatttcac acagtcactg ggatcgcgag tggtacatgg
    23641 cttacgaaca acaccacatg cgtctgatta acttaataga tgacctgtta gaagtttttc
    23701 aaacggatcc tgattttcat agttttcatt tggatgggca aaccattatc ctagatgatt
    23761 atttgcaagt acgccccgaa cgagaacctg agattagaca agccattgct tcgggaaaac
    23821 tccgtatcgg acctttctat atcttacagg acgatttttt gaccagcagt gaatccaatg
    23881 tgcgcaatat gctgattggt aaggaagatt gtgacagatg gggcgctagt gtgccacttg
    23941 gttattttcc tgataccttt ggaaatatgg gacaaacacc acagctgatg ttaaaagccg
    24001 gcctacaagc tgctgccttt ggtcgtggca ttcgtccaac tggatttaac aatcaagtag
    24061 ataccagtga aaaatacagc tcacaattct ctgaaatcag ttggcaaggc ccagataaca
    24121 gtcgtattct tggactcctc ttcgccaact ggtacagcaa tggcaatgag atcccgacaa
    24181 cagaagctga ggcgcgtctt ttttgggata aaaaacttgc tgacgccgaa cgctttgcct
    24241 caaccaagca ccttctgatg atgaacgggt gtgatcatca acccgtacaa cttgatgtca
    24301 ccaaggcaat cgccttagcc aaccaactct atcctgatta cgaatttgtg cattcctgct
    24361 ttgaagatta cttgtctgat ctcgcaaatg atttaccaga taacctttca accgtccaag
    24421 gagagattac cagtcaagag acagatggct ggtataccct agctaacacg gcttctgctc
    24481 gcatttacct caaacaggct aataccagag tctctcgtca actcgaaaac atcaccgaac
    24541 ccttagcagc aatggcttat gaggtgacaa gtacctaccc tcacgaccaa ctgcgttacg
    24601 cttggaaaac cctcacgcaa aatcaccctc atgattctat ctgtggttgt agtgttgata
    24661 gtgttcatcg ggaaatgata aaccgttttg aaaaagccta tgaagtcgga cactatttag
    24721 caaaagaagc tgcccagcaa attgctggcg cagttaacac gagtgacttt ccaacagata
    24781 gccaaccttt cctcttattt aataccagtg gccattccaa aacaagtgtt actgagctca
    24841 ccctgacctg gaaaaaatat tattttggcc aacgctttcc taaagaggtt taccaagaag
    24901 ctcaagagta tttggcagga ctctcccaat ctttccaagt cattgatgta tcaggaaaca
    24961 ctatctcaga agcagacatt ttggacacaa gcatcgcctt tgactacgat ttgcccaaga
    25021 gaaccttccg agaaccttat ttcgccatca aagtgagatt acggctacca ataactctcc
    25081 ctgccatgtc ttggaaagcc ttagcattac aactaggaaa cgagacagct ccttcagcaa
    25141 cggtcccact ctacgacgat agtaatcagt gccttgaaaa tgagtttcta aaagttatga
    25201 tacaaaccga tggccgtcta accatcaccg ataaacagtc aggggtgagc tatcaagatc
    25261 tcctacggtt tgaagattgt ggcgatattg gaaatgaata catttcccgc caaccaactc
    25321 atgaccaacc tttctatgcg gaccaaggga ccaccaagct taacatcatt agcaacaccg
    25381 ctcaagttgc tgaacttgaa atccagcaaa cctttgccat tcctatctcc gcagataagc
    25441 tcttacaggc tgagatggaa gctgtcattg acatcacaga acgccaagca agacgttcac
    25501 aagaaaaggc tgagctaacc ttaacaaccc ttatccgtat ggagaaaaac aatcctcgcc
    25561 tccaatttac cacacgtttt gataaccaaa tgacaaatca tcgcttgcgc gtcctattcc
    25621 caacgcacct taaaacagac catcatctag ctgacagtat ttttgaaact gtcaaacgtc
    25681 caaatcatcc agatgccacc ttttggaaga atccaagtaa cccacagcac caagaatgct
    25741 ttgtgagtct ctttgatggt gaaaatggag tcactattgg taactatggc ctcaacgaat
    25801 atgagatctt accagatacc aacaccattg ccatcactct cttacgttct gttggtgaaa
    25861 tgggcgactg ggggtatttc cctactcctg aagcccaatg cctcggcaaa cacagcctat
    25921 cttatagttt tgaaagcatc actaagcaaa cacaatttgc cagctattgg cgggcacaag
    25981 aaggccaagt tcctatccta gtcgaacaaa ccagccatca taagggaagc ttaagagcag
    26041 agcatagcta tgtcactggg gcagacgatc aagtcgctct aacggctttc aaacgtcgct
    26101 tagcagacaa tgcccttatc acgcgcagct acaatctttc aaacgataaa acttgtgact
    26161 ttagcctaag cctgccaaac tacaatgcta aggtcactaa tttgttagaa aaagacagca
    26221 agcaaagcac acccagccaa cttggcaaag ctgaaatttt aactctagct tggaagaaac
    26281 aataaactat tatcattagt aatagattaa catattcaaa aagagtctgg gactattgtc
    26341 tcagactctt aagttgattt tgagtgatta ttaatacctt taacatcagt caggcttagc
    26401 tatttctatt aactgggtta aaatgccatc atgaatctgc gagctaattg tgagatagtc
    26461 ataacgattt aaaatggtcg tgacattcct taagtcaaat tgccagtcat ctcttttttt
    26521 caaagccggt gtagcaaaca cgctttgact atcattttgt ccttgtttag tactgctttg
    26581 aatgactatg acaagtttat ggttttgatc cagaaatgct attgataagc aaggttgctt
    26641 tgtctccaaa ctcatttcta tagcattatc taacaaaaat gacaatagct tagtgaaatc
    26701 tactacttct agaaaaaacg ttgcaataca attaggaatc gatacctcaa ccttaagctt
    26761 cttatttttt gcctcaatta atttagctaa aacaatatgt ctgattgctt caacttgtaa
    26821 tttatctaaa caagttaaat caagtctgtc atctttagca ttattctttt cagcattcaa
    26881 gataccttca taagtaagtc tcacaataga gatatcattt tgttcgattc caatcttaag
    26941 acgactggac acggtagtta atagctgcct aagctcttga atatcttgat acagcaatcc
    27001 aaggtgctga ctataattaa tcagctcacg atattctttt tgttgcacaa ttgcctcaat
    27061 agagttttgt tttacataac gctctaaatg aattaataaa gtaagaaaca aaatgaaata
    27121 aaagagcact atgattgaac gagcagtcgt tgtagcaagt cctgataaag aaggcgacat
    27181 cacatctatc ccttggacac acaagtaata tagagccatc gaagagttag taaacactaa
    27241 tagtttacta gctctatgtg attgaaaata ttggcgccag gttgaaaaat cgaaatgaaa
    27301 aacttgaatg cagcgataaa tcaaaaaaat actaaagcaa gtaatgctgt aaatcagtag
    27361 tgtattatgt ttaacaactg aataaggcat accaaacaat ggcataacaa aaaatacaat
    27421 aaatcgctta accaaactaa tagacactag tggaaaaaag gcataaaaca ttaaaaactt
    27481 agcttttatt gatttaccat agtatagggc tataagcgca aagaaaagaa actgagccaa
    27541 catcacaaca tcaagaatga aatggtctgg aaagaaagcc caaaaaacta cttgaaacaa
    27601 aaccatacta agtgataaat aaaaaatatt tttcaggcga agcggaattg cacttacaaa
    27661 gctaaaaagc tttaacgtta acataatttc aataatatct aaaaatataa atcctaaaaa
    27721 ttgaagaaaa tcttctaaca tttatccttc tccttctcgt tcaaaatatg ttatcacatc
    27781 tcgattttct tttcatttcg aactccgtaa tagataaact gagctttttc attttaatca
    27841 tattctttat tttatcataa gttctgtcat tctaacagtt aaattacgaa aagcttgatt
    27901 aagtaacttt tctatattcc gatcatttta ctggttatca actcagattt atcagttgtt
    27961 gatctcatta taaacaagtg ttgcatttat ctttaatatc taacacataa agactcacac
    28021 agcctacagt ttttgcaaag gtttcttaca gcttaaaaga ttaaatcagg ataaatcctc
    28081 tatatcatcg ttcatattag catactaaaa taacttctgg taatgtaacc tcctgaccac
    28141 tcagttttct aatttatagc aaaaaacagc tttttttcaa caaccaattc ccctaatatt
    28201 gtctgtgtgt acttgctctt caaataaacc ctacgtagtg acaaactaac aaactttttt
    28261 aaccatgaat gtttctaaaa taaacataga gttatcaata atatgactat gcttagtaaa
    28321 ccgtttttga catccctact atgtcaagct attgctcaaa cccattacct gagcttataa
    28381 aacttgagtt gttattgcca gtcaatcata cacgtttttg taacttcacg acagcctcgg
    28441 tcctagctgt atgggggaac atgtctacac tttggatata gtgaacatcg taaacctttg
    28501 ttagctgcac caagtcgcgg gccaaagtgg aggtattaca agacacatac accatctgtt
    28561 taggctggta atgaagaatc gtttttaata atttatcatc taaaccagtt cttggtgggt
    28621 ccacaatgat ggcatccgcg cggtaacctt gtttatacca tttaggaata atatcctctg
    28681 ccttccctgc ctcatagtaa gcgttgtcaa agcccatggc tttggcattt ttttgtgcat
    28741 cttcaatcgc ttctgggata atatccatcc cccgcacaga cttgaccttc cctgcaaaag
    28801 caaagccaat cgagccaacc ccacaatagg catcaataat atgatctttg ctccctacat
    28861 ccaaggcctt caccacctca ccatacaaaa cttctgtctg ctgtggatta agttggtaaa
    28921 aagctctcgg tgataacgca aatccatagt ctaaaacttc ttcatgaatc gcctcttgtc
    28981 cccatagaat ttccgtttcg tccccataaa tctcactcga tttagaacga ttactattca
    29041 aggcaaccgt tttaacctga ggaaatgcct tagtcaattc gccaatgaaa ttcgctaacc
    29101 gaacttcttt gctactcaca acaataatct gtacctgatc actagcctgt gccttacgaa
    29161 ccattatcgt ccgaatccca gcaatcttgc gctcattgta aatgggcaac ttgtacttgt
    29221 ccactaactg cgtaatctta ttgataatat cttgcgttag ttgatcctgt accaagcaat
    29281 tgtcaatagg aaccaagcga tgacttccct gggaaaataa accagccttg accgtcccgc
    29341 caaatgaccg cagctgaaac tgcaatttgg ctcgatagtg atctggcttt ttcattccta
    29401 aagtcggtct aatctcaaat tgttcatagc cagttggttt gaacttttta agggcctgcc
    29461 taatcacatc atctttgaaa tctagctgtt taggataggc tagatgcatg atttggcaac
    29521 caccacaagt ttcataaaca gaacaagctg gtttgacacg attcttagaa gccttgttta
    29581 ccatcaacag tttggcctct gcaaaattcc gtttaaccga cgtgatttgg caaaaaatat
    29641 cttctccctt taaagcacca gggacaaata ccaaagtttt ctgataaaaa ccaatcccct
    29701 caccgttaat tcccattcgc ttaattttta aaggaatttt ctgtttaacc tttacgacca
    29761 tctcttcccc ttacttcctc taatatccta atctcaccac caaaagcatt cacaagcaac
    29821 acatttttag cagtattttc gtcttctatt ttaccatttt tgatataatg aacatatgaa
    29881 aatcactaaa attgaaaaga aaaaacgcct ctaccttatc gaattggata atgacgattc
    29941 cctttatgta acagaagata ctattgttcg gtttatgttg agtaaagata aagtccttga
    30001 caatgatcag cttgaagaca tgaaacattt tgcccaactg tcctacggca aaaatttagc
    30061 cctttatttt ctttcctttc aacaacgcag caacaagcaa gttgctgatt acctgcgcaa
    30121 gcatgagatt gaagaacaca ttattgctga catcatcact caactccaag aagaacaatg
    30181 gatagacgac accaaattgg ctgataccta cattcgccaa aatcagttaa atggtgataa
    30241 aggtccccaa gtcttaaaac aaaagttatt acaaaaaggc attgcaagtc atgacattga
    30301 tcctatctta tctcaaactg actttagcca actcgctcaa aaagtaagcc aaaaactctt
    30361 tgacaaatat caagaaaaat tgccaccaaa agccttgaaa gataaaatca cccaagcatt
    30421 actgaccaaa ggcttttcat acgatctagc taaacatagc ctcaatcacc ttaattttga
    30481 ccaagataat caagaaatag aagatcttct tgacaaagaa ttagacaaac aatatcgtaa
    30541 actcagtcgc aaatatgatg gttatacttt aaagcaaaag ctctatcagg ctctctaccg
    30601 aaaaggctac aacagcgacg atattaattg caagttaaga aattatttat agactgacaa
    30661 aagaagtgat tttttcacac atttatgata gactatagag gataagttta attgtagaaa
    30721 gttggtaagg catgaaatta cctaaagaag gcgactttat tacaattcaa agttataagc
    30781 atgatggtag tttgcaccgt acttggcgcg atactatggt actaaaaaca actgaaaatg
    30841 ccctcattgg agttaatgat cacactcttg tcacagaaag tgacggtaga cgatgggtga
    30901 cccgcgaacc tgcaatcgtt tactttcata aaaaatactg gtttaacatt atagccatga
    30961 ttcgagataa tggcgtctct tattactgta acttagctag tccatacatg atggacactg
    31021 aggccctcaa atacattgat tacgatttag atgtcaaagt ctttgcggat ggtgaaaaga
    31081 gattacttga tgttgatgaa tacgagattc ataaaaaaga gatgcagtat tcagccgata
    31141 tggactttat cctaaaagaa aatgtcaaaa tattggttga ttggattaat catgaaaaag
    31201 gaccattttc caaggcctat atcactattt ggtacaaacg ttatcttgaa ctgaagaatc
    31261 gttaagagtt gtccagcact cccaaggagt gctcagaacg cagacaaact cagttttagg
    31321 ctcaaaaagc atgaacagct ctgctgattt gacatccaat ttcctatttc tgcgtgtgga
    31381 gtgagccaaa acagatgttt ttcgttgtgg taaaagtggc gtcaatgtta atgttgacgc
    31441 cacttggcat ttttgagcct aggatctcaa aaataaggca tggaattcca aagaaagtcg
    31501 ctgccttaag cactacctaa ggaaagtatc aaaaaatact aagtttagta gcgaggaaat
    31561 ctccgacgaa agagagtact cactactttt tctttgcgtt aaagtagaag tgtcttgtta
    31621 agtcgcaaag tcttttggca cttgatgttg taaccaaaac tgacaagaca cctcttttag
    31681 gtagaatttt atcaaagtat gtaggacgct tgacgtcgtg tattgaaaat gaaaccacta
    31741 aaataaggaa tcattcaaga caaaacgata ccatcggcct caatcatctt cttggaaact
    31801 tgaaaaccgt ccataaccct gagattatcc ttaaaacgat taatgtctat tctcgtcgtc
    31861 ttcaggtttt ttcgcagata atggctacgc ttatactcgg tttaatcctt tagaagctaa
    31921 gaagcaattg aatagcctgc acgttcgtaa aacagacaaa attgacactg agaagaagtc
    31981 taataaaatc tgacagaaga tattgtggga gttaagaatc gtctgcataa gcttttccaa
    32041 gtcacctttt gtcttactat aactgctaaa attaccatta aaaccacatt aagatctcca
    32101 taccatccat tactatccat taattaaaca atttcttcta taatgggatt tgtaatatgt
    32161 gcatacaacc tacaacaaca catgacttga gaacattgta aagtgtcttt taaacctcaa
    32221 tctgcaatta aaaagaaaca ataaaaagct taaatttgtt gtataacaaa tttaagcttt
    32281 ttatcattaa aatacaatca accaagttag ttcgattact ttaaccaaag ttactaaata
    32341 g
//
LOCUS       DATWEK010000018        31819 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.018, whole genome shotgun sequence.
ACCESSION   DATWEK010000018 DATWEK010000000
VERSION     DATWEK010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31819
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.018"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            47..119
                     /locus_tag="VCR92_001020"
     tRNA            47..119
                     /locus_tag="VCR92_001020"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:80..82,aa:Phe,seq:gaa)
     gene            139..219
                     /locus_tag="VCR92_001021"
     tRNA            139..219
                     /locus_tag="VCR92_001021"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:173..175,aa:Tyr,seq:gta)
     gene            226..296
                     /locus_tag="VCR92_001022"
     tRNA            226..296
                     /locus_tag="VCR92_001022"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:258..260,aa:Trp,seq:cca)
     gene            308..380
                     /locus_tag="VCR92_001023"
     tRNA            308..380
                     /locus_tag="VCR92_001023"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:341..343,aa:His,seq:gtg)
     gene            389..460
                     /locus_tag="VCR92_001024"
     tRNA            389..460
                     /locus_tag="VCR92_001024"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:421..423,aa:Gln,seq:ttg)
     gene            480..563
                     /locus_tag="VCR92_001025"
     tRNA            480..563
                     /locus_tag="VCR92_001025"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:514..516,aa:Leu,seq:caa)
     gene            823..1008
                     /locus_tag="VCR92_001026"
     CDS             823..1008
                     /locus_tag="VCR92_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268100.1"
                     /translation="MSFEIFTLIIGWKLVGYRVMECGSSFKQGDYRLVVHICLLNVRD
                     EMLSQQGHEDKADWPEP"
     gene            1646..1954
                     /locus_tag="VCR92_001027"
     CDS             1646..1954
                     /locus_tag="VCR92_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2C-methyl-D-erythritol
                     kinase"
                     /protein_id="HEP4268101.1"
                     /translation="MKHRFQVKRGVSVYLEKRIPMCAGMGGGSSDAVTIRALNQLWLL
                     TLSRKDMMDIGIPIGSDVPYCLLSGRAQVTGKGEVVCRILGLLSSWVVLVKPDFGIST
                     "
     gene            2009..2221
                     /locus_tag="VCR92_001028"
     CDS             2009..2221
                     /locus_tag="VCR92_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2C-methyl-D-erythritol
                     kinase"
                     /protein_id="HEP4268102.1"
                     /translation="MVAAIEAGNYNDGILTEMNNLLEDIFIAKRPFIQKIKEKTLQAG
                     AATTLMTGSGPTVFALCQTEKQTIIV"
     gene            2331..2774
                     /locus_tag="VCR92_001029"
     CDS             2331..2774
                     /locus_tag="VCR92_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEP4268103.1"
                     /translation="MGTLEKKLDNLVNTILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQQRLTNTDLAKALNISQAAVTKAIKSLVKQDMLAGTKDTVDARVTYFELTELAK
                     PIASEHTHHHDETLNVYNRLLQKFSAKELEIVDKFVTVFAEELEG"
     gene            2778..3497
                     /locus_tag="VCR92_001030"
     CDS             2778..3497
                     /locus_tag="VCR92_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEP4268104.1"
                     /translation="MRYISVKNLSFQYESEPVLEGITYHLDSGEFVTMTGENGAAKST
                     LIKATLGILQPKAGRVTIAKKNKDGKQLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFRHLNKHDEEHVQASLEAVGMWENRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHQHGKSVLMITHDPEEVKAYADRNIHLVRNQKLP
                     WRCFNIHEVETDDEKGGHGHA"
     gene            3490..4305
                     /locus_tag="VCR92_001031"
     CDS             3490..4305
                     /locus_tag="VCR92_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEP4268105.1"
                     /translation="MLDILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLMSDTLS
                     HVSLAGVALGVVLGISPTITTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLALS
                     LIIMSKSHSSSSMSLEQYLFGSIITISMEQVVALFAIAAIILILTVLFIRPMYILTFD
                     EDTAFVDGLPVRLMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKT
                     VILLGIVIGFSGMLSGIFLSYFFETPASATITMIFISIFLLVSLGGMLKKRLF"
     gene            complement(4345..4728)
                     /locus_tag="VCR92_001032"
     CDS             complement(4345..4728)
                     /locus_tag="VCR92_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEP4268106.1"
                     /translation="MTECIFCHQLKANQLLTQSQYFKVVFDIDPIQKGHLLLISKDHY
                     TSLTQLPKEVRYDLIDLQAALVAKLEQHLPISGVTSVSNDKELMDEGTHFHLHLIPRL
                     TNDSFWESITINQENWDLTPFLKHL"
     gene            complement(4779..6035)
                     /locus_tag="VCR92_001033"
     CDS             complement(4779..6035)
                     /locus_tag="VCR92_001033"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEP4268107.1"
                     /translation="MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIK
                     GQLSTFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIET
                     GISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLFLDE
                     IAEIETQFNAARHERLAQKTLAREVVTLVHGEEAYKQALNITEQLFAGNIKNLSANEL
                     KQGLSNVPNYHVQSEDSLNLVDMLVTAGISPSKRQAREDVQNGAIYINGDRVQDLDYQ
                     LSNDDKIDDQLTVIRRGKKKYAVLTY"
     gene            6127..8439
                     /locus_tag="VCR92_001034"
     CDS             6127..8439
                     /locus_tag="VCR92_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEP4268108.1"
                     /translation="MRYFMVKWNTKQKRISHQRLGLLDLGPVLLRTLRLLSNFFYIVI
                     FLFGMMGFGMAFGYLASQIESVKVPSKESLVKQVESLTMISQMNYSDNSLISTLDTDL
                     LRTPVANDAISENIKKAIVSTEDEHFQEHKGVVPKAVFRATLASVLGFGEASGGSTLT
                     QQLVKQQVLGDDPTFKRKSKEIVYALALERYMSKDNILCDYLNVSPFGRNNKGQNIAG
                     VEEAARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLSTGQLKSEKDMAYGIKRQQN
                     VLYNMYRTGVLSKKEYEDYKAYPIQKDFIQPGSAIVNNHDYLYYTVLADAKKAMYSYL
                     IKRDKVSSRDLKNDETKAAYEERALTELQQGGYTITTTINKPIYNAMQTAAAQFGGLL
                     DDGTGTVQMGNVLTDNATGAVLGFVGGRDYALNQNNHAFNTIRSPGSSIKPIIAYGPA
                     IDQGLMGSASVLSNYPTTYSSGQKIMHADSEGTAMMPLQEALNTSWNIPAFWTQKLLR
                     EKGVDVENYMTKMGYKIADYSIESLPLGGGIEVSVAQQTNAYQMLSNNGLYQKQYIVD
                     KITASDGTVVYKHENKPIRIFSAATATILQELLRGPITSGATTTFKNRLAAINPWLAN
                     ADWIGKTGTTENYTDVWLVLSTPKVTLGGWAGHDDNTSLAPLTGYNNNSNYLAYLANA
                     INQADSNVIGVGQRFNLDPGVIKANVLKSTGLQPGTVNVNGHTFSVGGEMTTSLWSQK
                     GPGAMTYRFAIGGTDADYQKAWGNFGFRKN"
     gene            8703..12269
                     /gene="rpoB"
                     /locus_tag="VCR92_001035"
     CDS             8703..12269
                     /gene="rpoB"
                     /locus_tag="VCR92_001035"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEP4268109.1"
                     /translation="MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVNKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGESDLVR
                     NTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLIARFFDARRYDLAAVG
                     RYKVNKKLNIKTRLLNQIIAENLVDAETGEILVEAGTEMTRSVIESIEEHLDGDLNKF
                     VYTPNDYAVVTEPVVLQKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRATGRVTNEIV
                     WLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFSASVVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAEKVEIRRQDGSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIAD
                     GPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGASSEDLWDTVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK"
     gene            12360..16001
                     /gene="rpoC"
                     /locus_tag="VCR92_001036"
     CDS             12360..16001
                     /gene="rpoC"
                     /locus_tag="VCR92_001036"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020904830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEP4268110.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKLQ
                     EYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSASGQKRIKAVRRLDVLDAFN
                     KSGNKPEWMVLNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPGQDIQEVIDRLDINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIDAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGNVVEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKRLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDISDFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHTEVSA
                     EAVFTAEAE"
     gene            16153..16518
                     /locus_tag="VCR92_001037"
     CDS             16153..16518
                     /locus_tag="VCR92_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEP4268111.1"
                     /translation="MYQVIKMYGDWEPWWFIDGWQDDIIDEQQFSDWQEALDYFNQEW
                     QRMKAIFPSYHSQKNLLATFWEKEDKRWCEDCDEDLQQFHSLLLLKNKDIVPSNNYIP
                     EFEQRNDSPQVAYLCKLNL"
     gene            16611..17549
                     /gene="tadA"
                     /locus_tag="VCR92_001038"
     CDS             16611..17549
                     /gene="tadA"
                     /locus_tag="VCR92_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEP4268112.1"
                     /translation="MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVD
                     VYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYKLSKDKQLSLRLSSVGDYRGQES
                     LVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISSYHQEA
                     QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAV
                     IRASLTGAMVFSTVHAKSISGVYVRLLELGVTKAELSNCLALIAYQRLLNGGALIDST
                     QNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII"
     gene            17533..18519
                     /locus_tag="VCR92_001039"
     CDS             17533..18519
                     /locus_tag="VCR92_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEP4268113.1"
                     /translation="MKKLSSKHQHKFIQLLANLLSTGFSFAEVIAFLKRSQLLQLDYV
                     LKMEESLLKGQDLADMLSGLGFSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRR
                     KTVEVITYPLILLLFLFVMMLGLRRYLVPQLETQNQITYFLNHFPAFFIGFCSGLILL
                     FGMVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGQGLDLMTILDI
                     MAIEKSSLMKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELE
                     IYAQESWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAAILLPIYQNMGGIF"
     gene            18521..18847
                     /locus_tag="VCR92_001040"
     CDS             18521..18847
                     /locus_tag="VCR92_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEP4268114.1"
                     /translation="MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKD
                     RVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKADGSITEKQEKAYQDYYDKHKNE
                     KARLSN"
     gene            18822..19250
                     /locus_tag="VCR92_001041"
     CDS             18822..19250
                     /locus_tag="VCR92_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEP4268115.1"
                     /translation="MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEH
                     LFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTEGNSLTVPKSITVNHPYRLVIDQ
                     MGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP"
     gene            19255..19491
                     /locus_tag="VCR92_001042"
     CDS             19255..19491
                     /locus_tag="VCR92_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEP4268116.1"
                     /translation="MIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQT
                     RTKEITLNGCHITILRTDRYISIHDDEGEVMKIE"
     gene            19484..19918
                     /locus_tag="VCR92_001043"
     CDS             19484..19918
                     /locus_tag="VCR92_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEP4268117.1"
                     /translation="MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYL
                     ARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEKGKKVLAFGQFKSHDFRKSASNG
                     KGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD"
     gene            19902..20228
                     /locus_tag="VCR92_001044"
     CDS             19902..20228
                     /locus_tag="VCR92_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEP4268118.1"
                     /translation="MPFKTNLKAGILLYAMFMASIFLLVLQVYLSQVTALHKEYQAQT
                     DYVKARLIAEIVYQDHRYKASNPVFFKGGQVICRERKERWMLIVKLDQQRQYQFEYLK
                     PKQYSQ"
     gene            20326..21279
                     /locus_tag="VCR92_001045"
     CDS             20326..21279
                     /locus_tag="VCR92_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEP4268119.1"
                     /translation="MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEG
                     ASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQTEQLQANHQFTPDAIGFILLYLL
                     EQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
                     AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSL
                     KYLKKDGFAIFLAPVNLLTSPQSQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIV
                     LQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN"
     gene            21338..22534
                     /locus_tag="VCR92_001046"
     CDS             21338..22534
                     /locus_tag="VCR92_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEP4268120.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEEVLAQGIIERIGLKDSISTV
                     KYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVV
                     VNDKVLEQIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYH
                     GKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSG
                     VSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGEISTPESKVKVLVISTDEELCIARDVE
                     RLKNTK"
     gene            22721..23029
                     /locus_tag="VCR92_001047"
     CDS             22721..23029
                     /locus_tag="VCR92_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268121.1"
                     /translation="MYVFIEPNDLKDYLITVYDERNRAIRKQTQVYCFYLMIVLFVAL
                     FFFFPCLTIRDLVSYKLALIFAYLYLIIRSLVAKKMEALGKITTNSQKPPFDTSQVLC
                     "
     gene            complement(23112..23882)
                     /locus_tag="VCR92_001048"
     CDS             complement(23112..23882)
                     /locus_tag="VCR92_001048"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEP4268122.1"
                     /translation="MKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLT
                     LPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQD
                     LPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRNLTDSFGSTFDISEKDFDTFTA
                     LAGSSPAYIYLFIEALAKAGVKNGMPKAKALEIVTQTVLASASNLKTSSQSPHDFIDA
                     ICSPGGTTIAGLMELERLGLTTTVSSAIDKTIDKAKSL"
     gene            complement(23930..24997)
                     /gene="pepA"
                     /locus_tag="VCR92_001049"
     CDS             complement(23930..24997)
                     /gene="pepA"
                     /locus_tag="VCR92_001049"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEP4268123.1"
                     /translation="MTDLFSKIKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGL
                     GGIFGIRDSKAEKAPRILVAAHMDEVGFMVSDIKVDGTLRVVGIGGWNPLVVSSQRFT
                     LYTRTGQVIPLISGSVPPHFLRGANGSASLPNIENIVFDGGFTDKAEAESFGITPGDI
                     IVPQSETILTANQKNIISKAWDNRYGVLMITEMLEALKGQDLNNTLIAGANVQEEVGL
                     RGAHVSTTKFDPELFFAVDCSPAGDIYGNPGTIGDGTLLRFYDPGHVMLKDMRDFLLT
                     TAEDAGVNFQYYCGKGGTDAGAAHLQNGGVPSTTIGVCARYIHSHQTLYAMDDFVEAQ
                     AFLQAIIKKLDRSTVDLIKRY"
     gene            25453..25746
                     /locus_tag="VCR92_001050"
     CDS             25453..25746
                     /locus_tag="VCR92_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEP4268124.1"
                     /translation="MRDMSKKKIGMISGIFGFSLAIGLGIVIKDYCQDRQRRQMTRDL
                     RTFFSPLGQIEVLYINPCQVKQDYISGGVVMSNGKQYQFTYHSRQISFEEDKG"
     gene            25743..26060
                     /locus_tag="VCR92_001051"
     CDS             25743..26060
                     /locus_tag="VCR92_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEP4268125.1"
                     /translation="MIRPTSYESLAALIEKEDKLVLFFTADWCPDCQFIYPIMPEIEA
                     ELTDMTFICVNRDQFIEVAQKWNIFGIPSFVVIEKGQEVGRLVNKMRKTKTEIMHFLA
                     AYQ"
     gene            26078..26704
                     /locus_tag="VCR92_001052"
     CDS             26078..26704
                     /locus_tag="VCR92_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEP4268126.1"
                     /translation="MIFAYNKEQVGDVLMVILQDTKDIKRQVERKGKVARVFAEESGK
                     TLAWNIFEVSSLITIEGNGQIFLTDEDLARLNAELAKEGFSERLEPTVGPVFVVGQIV
                     EMVAHPDSDHLNICQVAIGEDQTVQIVAGAPNAALGLKTIVALPGAIMPNGSLIFPGK
                     LRGEESYGMMCSPRELVLPNAPQKRGIIELDESAVVGEAFDPAKHWKG"
     gene            26856..27251
                     /locus_tag="VCR92_001053"
     CDS             26856..27251
                     /locus_tag="VCR92_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEP4268127.1"
                     /translation="MYNKVIAIGRLVAKPELVKTATDKHVARLSLAVNRRFKNASGER
                     EADFISIVVWGKLAETLVSYASKGSLMSIDGELRTRKYDKDGQVHYVTEVLCQSFQLL
                     ESRAQRAMRENNVTNDLVDLVLEEDTLPF"
     gene            complement(27512..28153)
                     /locus_tag="VCR92_001054"
     CDS             complement(27512..28153)
                     /locus_tag="VCR92_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEP4268128.1"
                     /translation="MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAVDNNPVLDLYYQ
                     DPKKYAFLLQIYFLNKRFKSIKEAYQADNNILDRSIFEDELFLKLNYKNGNVTKTELD
                     IYQELLANMLEELEGMPKKRPDLLIYIDVSFDKMLERIEKRGRSFEQVDGNPSLEQYY
                     HQVHGEYPTWYEDYKVSPKMKIDGNSLDFVQNPQDLATVLKMIDTKLKELHLL"
     gene            complement(28173..29150)
                     /gene="dusB"
                     /locus_tag="VCR92_001055"
     CDS             complement(28173..29150)
                     /gene="dusB"
                     /locus_tag="VCR92_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEP4268129.1"
                     /translation="MTKLNSSFRIGDVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDENEHPMSIQLFGGDAEGLKRAADFIQTNTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIVKEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAESAGVSALAMHGRTREQMYTGTCDHETLARVSKAITKIPFIGNGDVRSVQDAK
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGQELPDLPFAKKLDIAKDHLKRLIN
                     LKGETIAVREFRGLAPHYLRGTAGAAKVRGAVSRAETLAEVEAIFKTVR"
     gene            complement(29137..30009)
                     /gene="hslO"
                     /locus_tag="VCR92_001056"
     CDS             complement(29137..30009)
                     /gene="hslO"
                     /locus_tag="VCR92_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEP4268130.1"
                     /translation="MDKIIKSIAQSGAFRAYVLDSTETVALAQEKHNTLSSSTVALGR
                     TLIANQILAANQKGDSKITVKVIGDSSFGHIISVADTKGHVKGYIQNTGVDIKKTATG
                     EVLVGPFMGNGHFVTIIDYGTGNPYTSTTPLITGEIGEDFAYYLTESEQTPSAIGLNV
                     LLDENDKVKVAGGFMVQVLPGASEEEIARYEKRLQEMPAISHLLASKNHVDALLEAIY
                     GDEPYKRLSEEPLSFQCDCSRERFEAALMTLPKADLQAMIDEDKGAEIVCQFCGTKYQ
                     FNENDLEALINDKA"
     gene            complement(30156..31649)
                     /gene="rofA"
                     /locus_tag="VCR92_001057"
     CDS             complement(30156..31649)
                     /gene="rofA"
                     /locus_tag="VCR92_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047149466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RofA"
                     /protein_id="HEP4268131.1"
                     /translation="MIEKYLESSIESKCQLIILFFKTSYLPITEVAEKTGLTFLQLNH
                     YCEELNAFFPGSLSMTIQKRMISCQFTHPFKETYLYQLYASSNVLQLLAFLIKNGSHS
                     RPLTDFARSHFLSNSSAYRMREALIPLLRNFELKLSKNKIVGEEYRIRYLIALLYSKF
                     GIKVYDLTQQDKNTIHSFLSHSSTHLKTSPWLSESFSFYDILLALSWKRHQFSVTIPQ
                     TRIFQQLKKLFVYDSLKKSSHDIIETYCQLNFSAGDLDYLYLIYITANNSFASLQWTP
                     EHIRQCCQLFEENDTFRLLLNPIITLLPNLKEQKASLVKALMFFSKSFLFNLQHFIPE
                     TNLFVSPYYKGNQKLYTSLKLIVEEWMAKLPGKRDLNHKHFHLFCHYIEQSLRNIQPP
                     LVVVFVASNFINAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPDLKPDLVITHSQL
                     IPFVHHELTKGIAVAEISFDESILSIQELMYQVKEEKFQADLTKQLT"
BASE COUNT         9511 a         5737 c         6916 g         9655 t
ORIGIN      
        1 cgtaggttca aatcctgctc ccgcaataca taagtatgta gttgttggct cggtagctca
       61 gttggtagag caatggattg aagctccatg tgtcggcggt tcgattccgt ctcgcgccat
      121 taaaatttaa tattttacgg aaagatagcg aagaggctaa acgcggcgga ctgtaaatcc
      181 gctccttcgg gttcgggggt tcgaatccct ctctttccat cctaaacggg catagtttaa
      241 aggtagaact aaggtctcca aaaccttcag tgtgggttcg attcctactg cccgtgttag
      301 aaatatggcg ggtgtggtga agtggttaac acatcagatt gtggctctga cattcgtggg
      361 ttcgattccc atcactcgcc tattttattg gggtatagcc aagcggtaag gcaagggact
      421 ttgactccct catgcgttgg ttcgaatcca gctaccccag tttaaatttt atatttaaag
      481 ccggcgtggc ggaattggca gacgcgctgg actcaaaatc cagtgtccgc aaggacgtgc
      541 cggttcgacc ccggccgccg gtatacttga aaaacaaggt ttacaaacct tgttttttgt
      601 tttgatctta agctgtagct acgtagtaca atctcttata ttactgataa ggtctattta
      661 atgcgcaaga tttgtggtat gatgaatatg attgagtatt gatgctttat gggattaccg
      721 gtaaggtttt gaaaaaggtt tgtcactact aggtgctttt ttagctatag aaagacagtt
      781 atggattgat gtattgtaac taatgttgga ggttaatggt ggttgagttt tgagatattt
      841 acactgataa tcgggtggaa actggttggg tatcgggtaa tggagtgtgg ttcttcgttt
      901 aagcaaggag attatcgttt ggtggttcat atttgcttgt taaatgttag ggatgagatg
      961 ctgagtcagc aaggccatga agataaagct gactggccag agccttgaga tgtgacgttt
     1021 ggtggaagtc ctttttggtg agatggcaca gcatatagta atattagatc ctgaggaaga
     1081 attgggactt tcattaggct tgactggggt atgacctcac tttacaattc atttcgatga
     1141 tgggtttgat gatacgtttt tagttcagga ctttgtagag ttggagaatt tggttcttta
     1201 tgaggaagaa gtgcaggtaa ttcgttgaga cagtcgtgaa gatattttag gtatgattga
     1261 tgaaggtttg ttcattcctt atctgaagta taaaataaat ttgtgctttg agatggttgg
     1321 ccaatataaa gtccatcaat cttagaagta ataatttttg aattttttct gaggtttgtg
     1381 tatatttgat agtgtactga tgtaagaagt aaggagtact atgatggcaa tcaatgagag
     1441 agcttctgta aaaatcaagt taggccttga tactaagaat aagcgatgag atggttacca
     1501 cgatttatcg atggtcatga tgagtattga tctgtgtgac tatgtgacgg ttgaccatat
     1561 agatgacaat aagattgtct ttgcctcaaa ctgtccgaaa atacctatta actaagataa
     1621 tgatgtttat aagatagttc agctaatgaa acatcgattt caagttaaaa gaggagtttc
     1681 cgtttacttg gaaaagcgga ttcccatgtg tgctggtatg ggaggaggtt ctagcgatgc
     1741 tgttactatc agagcattaa atcagttatg gctccttact cttagccgaa aagatatgat
     1801 ggatattggt ataccgattg gtagtgatgt gccttattgc ttgctttcag gtcgtgccca
     1861 agtcactggt aaaggtgaag tggtttgtcg cattttgggg ctgttatcgt cttgggtggt
     1921 tttggttaaa ccagattttg gtatctcgac ttgaacattt tttctagata ttaattgtaa
     1981 aatcatttca agagtgtcta ctactcattt ggttgcggcg attgaagcgg gtaactataa
     2041 tgatgggata ttgactgaaa tgaacaattt gctggaagat attttcattg ccaagcgacc
     2101 ctttattcaa aaaataaaag agaaaacact gcaagctggt gctgctacta ctttgatgac
     2161 aggaagtgga ccgactgttt ttgctttgtg ccagaccgaa aaacaaacta taatagttta
     2221 aaaggacttt gcaaggaagt ttttaaggtg agaatgttgt aatattttgt tgggattgct
     2281 tctttggaag cttcatgtta taattaactg gttaatgaaa gaggagattt atggggactt
     2341 tagaaaaaaa acttgataac ttagtaaata ctattttatt aaaagcagaa aatcagcatg
     2401 agttattatt tggagcttgt caaagtgacg ttaagcttac taatacgcaa gaacatattt
     2461 taatgttact atctcagcaa cgtctcacta atacagattt ggctaaggca ttaaatatta
     2521 gtcaggcggc agtaactaag gctatcaaga gtttggtcaa acaagacatg ctagcaggaa
     2581 ctaaggatac ggttgatgct agggtgactt attttgaatt aaccgagtta gctaagccta
     2641 ttgcgtcaga acatacccat catcatgatg aaaccttaaa tgtttacaac cgtttattac
     2701 aaaaattctc cgcgaaagaa ttagagattg tagataagtt tgtaacagtt tttgctgagg
     2761 aattagaagg gtaatccatg agatacatat cagtgaaaaa tctctccttt caatatgaaa
     2821 gtgagccagt tttagaaggg atcacttatc atttagatag tggagaattt gtcaccatga
     2881 ccggtgaaaa tggcgctgca aagtcaacct taataaaagc aaccttagga attttacaac
     2941 caaaggctgg acgagttact attgctaaaa aaaataaaga cggtaaacaa ttaaggattg
     3001 cttacttgcc gcagcaagta gctagcttta acgctggttt tccatccacc gtttacgagt
     3061 ttgtcaaatc aggtcgctac ccacgtagtg gttggtttag acatttgaac aaacacgatg
     3121 aagagcatgt gcaagcaagc ttagaagcag tcggcatgtg ggaaaaccgt cataagagaa
     3181 ttggtagttt atcaggtggt caaaaacaac gtgtggttat tgcccgtatg tttgcttctg
     3241 accctgatat ttttgtgcta gacgagccaa caacgggaat ggatagcggt actactgata
     3301 ccttttatga actgatgcac cacagtgcac atcaacacgg gaaatccgtt ctgatgatta
     3361 cccatgaccc agaagaagtg aaggcttatg ctgatcggaa cattcattta gtcagaaacc
     3421 aaaaacttcc ttggcgttgt ttcaacattc atgaagttga aacagatgac gaaaaaggag
     3481 gtcatggtca tgcttgatat tttatcctat gatttcatgc aacgggcggt aatggcggta
     3541 gttgccatta gtatttttgc tccgatttta ggtattttcc ttattttacg tcgtcaaagt
     3601 ttgatgagcg atacccttag tcatgtttct ttggctgggg tagcgcttgg ggtagtcctt
     3661 ggtatttcac caaccatcac tactattatt gttgtggttt tagctgctat tttgttagaa
     3721 tacctgcgtg tagtttacaa acactacatg gagatttcaa cggcgatttt gatgtcactt
     3781 ggcttggccc tatctctgat tattatgagt aagtcgcata gttcatcaag catgagttta
     3841 gaacaatacc tttttggatc gatcatcacg attagtatgg aacaagttgt cgccttgttt
     3901 gctattgctg cgattatttt aatcttgacc gttctcttca ttagaccgat gtacattctg
     3961 acctttgatg aagatactgc ttttgtagat ggtttgcccg ttcgcttgat gtctgttcta
     4021 ttcaatatcg tcactggggt tgctattgct ttgaccattc cagcagcagg agcacttttg
     4081 gtttctacca ttatggtctt gccagcaagt atcgcaatga gattgggtaa aaactttaaa
     4141 acagttatct tactgggaat tgtcatcggt tttagcggta tgttatctgg tattttctta
     4201 tcttatttct ttgaaacgcc agctagtgcc actattacca tgattttcat tagtattttc
     4261 ctcttagtta gtctaggtgg aatgcttaaa aaacggttat tttaataaga aaaatcctca
     4321 catgtttaac atgtgaggat ttatttataa atgctttaaa aagggggtaa ggtcccaatt
     4381 ttcttgatta atggtgatgc tctcccaaaa gctatcatta gttaaacgag gaatcaaatg
     4441 aaggtgaaaa tgagtcccct catccatcaa ctccttgtca ttgctgacgc tagtgacgcc
     4501 tgaaatggga aggtgctgct ctagcttagc aactagagcg gcttgtaagt cgatgagatc
     4561 atagcgcact tcctttggta gttgtgtcag actagtgtaa tggtctttgg aaatcagtaa
     4621 aaggtgcccc ttttggatag gatcaatatc aaaaacaacc ttgaaatatt gactttgagt
     4681 cagtagctga tttgctttga gctgatggca aaagatacat tctgtcatag gtacatctcc
     4741 ttatgaaaaa acgagccaga gctcgtttaa tcggttatct agtaagtgag aacagcgtat
     4801 tttttcttac cgcggcgaat aacggttaat tgatcatcaa ttttatcatc attacttaat
     4861 tggtaatcta aatcttgaac gcggtctccg ttaatgtaga ttgctccatt ttgcacgtct
     4921 tcacgcgctt ggcgttttga tggggaaata cctgcggtga caagcatgtc aacaaggtta
     4981 aggctgtctt ctgattgaac gtgataattt ggtacattgc tcaatccttg ttttaattca
     5041 ttagcagaaa gatttttgat gtttccagca aataactgct cggtaatgtt aagagcttgt
     5101 ttataagctt cttcgccatg aaccaaggta accacttcgc gtgccaaggt tttttgagcg
     5161 agacgctcgt gacgagcggc attaaattga gtttcaattt ctgcaatctc atctagaaat
     5221 aagaaggtga agattttcaa gaaacgcact gcatcatcat ccatgacatt taaccagaat
     5281 tggtacatct cgtaaggaga cgtcttatcg gcatcaagcc agacggcatt accttctgat
     5341 ttaccgaatt ttttcccggt tgagtcagtg atgagtggta cagtcatgac gtgcccagtt
     5401 ttatcagcct ttttgcggag taattcagta ccagctgtca tattgcccca ctggtcagag
     5461 ccgccaattt gtaaggttac attatgcttg tcattgagtt cgtagaagtc gtagccctgc
     5521 atgatttggt aagcaaactc agtgtaagaa atgcctgttt caatgcgttt tttaacagag
     5581 tctttactca tcatgtagtt aacggtgaag tatttaccga catcacggag gaagtcaata
     5641 aagctgattt gcgagaacca gtcatagttg ttgacaagct ctgctttatt atcaccattt
     5701 tcaaaatcaa ggaaagtaga caactgccct ttaatcttgt cactccactc caaaactgtt
     5761 tctttggttt gaaggctgcg ctctgcatct ttaaaggaag gatcaccaat taaacctgtg
     5821 gcaccaccca caagagcgta aggtttgtgc cctgctagtt gcaagcgacg agatgttaag
     5881 atagccacta gatggcccag atgaaggctg tcagcggttg gatcataacc ggtataatag
     5941 gatacttgcc cttctgttaa tgctttgaca agggcttgtt catcagtcgt ttgaaagacc
     6001 aagccacgag ctttgagttc ttcaaaaata ttcataggct ttctccattt tcattatagt
     6061 ttcgaatcat tatatcaaaa aacgctactg ctatgcaagc tttatcaaag tttggtataa
     6121 tgataaatga ggtattttat ggtgaaatgg aacacgaaac aaaagcgtat aagtcatcaa
     6181 agattaggtc tcttggattt ggggccggtg ctattacgta cgttgagact actgtctaac
     6241 tttttttata ttgttatctt cctttttgga atgatgggat ttggtatggc atttgggtat
     6301 ttggctagtc agattgaatc tgttaaggta ccaagtaaag aaagtttagt caaacaagtt
     6361 gaatcattaa cgatgatttc gcaaatgaac tattctgata atagtttaat ttctacttta
     6421 gatacggatt tacttcgaac accagtagct aatgatgcga tttcagagaa tatcaaaaaa
     6481 gctattgtat caacagaaga cgaacatttt caagaacata aaggtgtcgt gccaaaagct
     6541 gtttttcggg caacattggc ttctgtattg ggatttggag aagctagtgg aggttcgacc
     6601 ttaacacagc aattggtcaa acaacaagtt ttgggagacg atcccacatt taagcgcaag
     6661 tctaaggaga tcgtttacgc tcttgcctta gagcgttata tgtccaaaga caatatctta
     6721 tgtgattatc ttaatgtttc accttttggt cgtaataaca agggccaaaa tattgctggt
     6781 gttgaagaag ctgcgcgtgg catttttggc gtttctgcca aagatttaac ggtgccacag
     6841 gcagcatttt tggcggggct tccgcagagt cctattgttt actctcctta tttgtcaacg
     6901 ggacaactga agtcagaaaa ggacatggct tatggcatca agcgtcagca aaatgttctc
     6961 tataacatgt accgtacagg tgttctgtct aaaaaagaat acgaggacta taaggcttat
     7021 ccgattcaaa aggattttat tcaaccggga agcgcaatag taaataatca cgattacctt
     7081 tattacacgg tgttagcgga tgctaaaaaa gccatgtata gctatttgat taagcgagat
     7141 aaggtgtcta gtcgtgactt gaaaaatgac gagactaagg ctgcttatga agagagagcc
     7201 ttaacagaat tgcaacaggg tggctatacc atcaccacaa ccattaataa gcctatttac
     7261 aatgcgatgc agacagcggc agctcagttt ggtggcctgt tagatgatgg cactggtaca
     7321 gttcaaatgg gaaatgtctt gacagacaat gcgactggtg ctgtgttagg ttttgttggt
     7381 ggtagagatt atgctctgaa tcaaaataat catgctttca atacaattag atcgccaggt
     7441 tctagcatta aaccgataat cgcttatggt cctgctattg atcaaggttt aatggggagt
     7501 gctagcgttt tgtctaatta cccaacaact tactcgagtg gccaaaaaat catgcatgct
     7561 gatagtgaag gaacagccat gatgccactt caagaggccc taaatacttc ttggaacatc
     7621 ccagcttttt ggacacagaa attactgcgt gaaaaaggtg tcgatgtcga aaattatatg
     7681 acaaaaatgg gttataagat tgcagactac tcgattgaaa gtttacctct agggggcggt
     7741 attgaagtct cggttgctca acaaaccaat gcttaccaaa tgctttcaaa caatggctta
     7801 tatcaaaagc aatatattgt agataagatc actgctagcg atggtacagt cgtttacaaa
     7861 catgaaaata agccaattcg tattttttct gcagcaacag ctacgatttt acaagaattg
     7921 ttgagaggtc cgattacttc aggcgctacg actactttca agaaccgttt ggcggctatt
     7981 aatccgtggc ttgctaatgc tgattggatt ggtaagaccg gaacaactga gaattatacg
     8041 gatgtttggc tagtcctgtc tactccaaaa gttaccttag gcggttgggc aggacatgat
     8101 gacaatacct cattagcgcc attaacagga tataacaata attctaatta ccttgcctat
     8161 ttagctaatg ccattaatca ggccgattcc aatgttattg gagtagggca acgtttcaac
     8221 ttagatccag gagtcattaa ggcgaatgtc ttgaagtcaa caggtttaca accaggaact
     8281 gttaatgtca atggacatac tttttctgtt ggtggagaaa tgaccaccag tctatggtcc
     8341 caaaaaggac cgggggctat gacttaccga tttgctattg gtggcacgga tgccgattat
     8401 caaaaagctt gggggaactt tgggttcaga aaaaattagg ttgccattta tcgataaaaa
     8461 gggtataata gcaataacta tttgtcgtcc aatctagctg aaatattgtc cagttaggaa
     8521 gaacagcagt taaatcacac tgataaagtc agatttagct gctctttttg tgtctatttt
     8581 tagaaaagat agggtttgta acctatattt aaatattcta aaaattaaca tttagggcaa
     8641 atgataactt agttgcgatt tgctgaaaca gcaaagctta aatagaagaa ggagctaaaa
     8701 acttggcagg acatgaagtt cgatacggaa aacaccgtac acgtcgtagc ttttcaagaa
     8761 tcaaagaagt tcttgattta ccaaatttga ttgaaattca aactgactca ttccaagatt
     8821 tcctcgattc aggtttgaaa gaagtatttg aagatgtact tcctatttca aactttacgg
     8881 atactatgga acttgaattt gttggttacg aatttaaaga acctaaatat acccttgaag
     8941 aagctcgtat ccacgatgca agttattctg caccaatctt tgttaccttc cgtttggtca
     9001 ataaagaaac tggtgagatt aaaactcaag aagtcttctt tggtgatttc ccaatcatga
     9061 cggaaatggg tacctttatt atcaatggtg gtgaacgtat catcgtttct cagttggtgc
     9121 gttctccagg tgtttatttc aacgataaag ttgataaaaa cggtaaagtt ggttacggat
     9181 caacagtgat tcctaaccgt ggggcttggt tggaattaga gactgactca aaagacattg
     9241 cctacactcg tattgaccgt acgcgtaaga ttccattcac aaccttggtt cgtgcccttg
     9301 gtttctcagg tgatgatgaa attgttgata tctttggtga aagcgacctt gttcgtaata
     9361 ccattgaaaa agacattcac aaaaatccaa gtgattctcg tacagacgaa gcccttaaag
     9421 aaatttacga gcgtcttcgt ccaggtgagc caaaaactgc agatagctct cgtagtctct
     9481 tgattgcgcg tttctttgat gcacgtcgtt acgatttggc tgcggttggt cgttacaaag
     9541 tgaacaaaaa acttaatatc aagactcgtc ttttgaacca aatcattgct gaaaaccttg
     9601 tggatgctga aactggcgaa attttggtag aagctggaac tgagatgact cgtagcgtca
     9661 tcgaatccat cgaagaacac cttgacggtg atttgaacaa gtttgtttac acaccaaatg
     9721 attacgctgt ggttactgaa cctgttgttc ttcaaaagtt caaggttgtg tcaccaattg
     9781 atcctgatcg tgtagtaact attgttggta atgccaatcc agatgataag gttcgtgcat
     9841 tgacacctgc tgatattttg gcagaaatgt catacttctt gaaccttgct gaaggtcttg
     9901 gaaaagttga cgatattgac cacttaggta accgtcgtat ccgtgccgtt ggtgaattgc
     9961 ttgccaacca attccgcatc ggtcttgctc gtatggagcg taacgttcgt gagcgtatgt
    10021 ctgttcaaga caacgatgtg ttaacaccac aacaaatcat caatatccgt cctgtcacag
    10081 cagctgtcaa agaattcttc ggttcgtctc agttgtcaca gttcatggac caacacaacc
    10141 cattgtcaga gttgtctcac aaacgtcgtt tatctgcctt aggacctggt ggtttgacac
    10201 gtgaccgtgc tggttatgag gttcgtgacg tgcattacac gcactatggc cgtatgtgtc
    10261 cgattgaaac acctgaagga ccaaatattg gtttgattaa caacttgtct tcatttggac
    10321 atcttaataa atatggtttc attcaaacac cttaccgtaa ggttgaccgt gcgactggta
    10381 gggtaactaa cgagattgtt tggttgactg ccgacgaaga agacgaatac acagttgcac
    10441 aggccaattc gaaactaaac gaagatggca cttttgctga agaaatcgtt atgggtcgtc
    10501 accaaggtaa taaccaagaa ttttctgcaa gtgttgttga tttcgttgac gtttccccta
    10561 aacaggtagt tgctgttgcg acagcatgta ttcctttctt ggaaaatgat gactccaacc
    10621 gtgctctcat gggtgccaac atgcaacgtc aggctgtgcc attgattgat ccaaaagcac
    10681 catatgttgg tactggtatg gaatatcaag ctgcccatga ctcaggcgct gcggtgattg
    10741 ctcagcacaa tggtaaagtt gtcttttctg atgctgaaaa agtggaaatc cgtcgtcaag
    10801 atggctcact tgatgtttac cacattacca aattccgtcg ttcaaactca ggaacagcct
    10861 ataaccaacg cacccttgtt aaagtaggag acattgttga aaaaggtgat ttcatcgctg
    10921 atggaccttc tatggaaaat ggtgaaatgg ctcttggaca aaacccagtc gttgcttaca
    10981 tgacttggga aggttataac tttgaggacg ctgttatcat gagtgagcgc cttgtgaaag
    11041 aagatgtcta cacatctgtt cacttggaag aattcgaatc tgaaacgcgt gatacaaaac
    11101 ttggccctga agaaatcact cgggaaatcc caaatgttgg tgaagaagcc ctcaaagacc
    11161 ttgacgaaat gggaattatc cgtatcggtg ctgaggttaa agaaggcgac atcttagtag
    11221 gtaaagtcac acctaaaggt gaaaaagacc tctctgctga agaacgttta cttcacgcca
    11281 tctttgggga taaatcgcgt gaagtgcgtg atacctcact tcgtgtccct cacggtggtg
    11341 atggtatcgt tcgtgatgtg aaaatcttta cacgcgctaa cggcgatgaa ttgcaatcag
    11401 gtgttaatat gcttgtgcgt gtttacatcg ctcaaaaacg taaaatcaag gtcggagata
    11461 aaatggccgg tcgtcacgga aacaagggtg tcgtttcacg tattgtacca gttgaagaca
    11521 tgccatacct tccagacgga acaccagttg acatcatgtt gaaccctctt ggggtgccat
    11581 cacggatgaa tattggtcag gttatggaac ttcaccttgg tatggctgct cgtaatcttg
    11641 gcattcacat tgcaacacct gtctttgacg gggcttcatc agaagacctt tgggacactg
    11701 ttcgtgaagc tggtatggat agcgatgcta agacggtcct ttatgatggt cgcaccggtg
    11761 aaccatttga caaccgtgta tccgttggtg tcatgtatat gatcaaactt caccacatgg
    11821 ttgatgataa acttcatgcc cgttctgtag gaccatactc acttgttacc caacagccac
    11881 ttggtggtaa agctcaattt ggtggacaac gttttggtga gatggaggtt tgggcccttg
    11941 aagcttatgg tgcatcaaat gttcttcaag aaatcttgac ctacaagtca gatgacgtca
    12001 caggacgttt gaaagcctat gaagcgatta ctaaaggtaa accaattcca aaaccaggtg
    12061 taccagaatc cttccgtgtt cttgtaaaag aattgcaatc gcttggtctt gatatgcgtg
    12121 tgcttgacga ggatgataat gaagtggaac ttcgtgatct tgatgaaggt gaagacgatg
    12181 acattatgca tgttgacgat ctcgagaagg cacgtgaaaa acaagctcaa gaaacccaag
    12241 aagtttctga aacaactgac gaaaaataag caatcaattc ttattaaata attatttact
    12301 ggtctggggc aaaggcccca ggaactggta aagtcatcaa aggcagaaag gtaaaactag
    12361 tggttgacgt aaatcgtttt aaaagtatgc aaatcacatt agcctcacca agtaaggtcc
    12421 gttcatggtc ttatggtgaa gttaaaaaac ctgaaacaat caactaccgt acattaaaac
    12481 cagaacgtga aggactcttt gacgaagtca tctttggtcc aacaaaagac tgggaatgtg
    12541 cgtgtggtaa gtacaaacgt atccgttata aagggatcgt ttgtgaccgc tgtggggttg
    12601 aggtaactcg tgctaaagta cgtcgtgaac gtatgggtca cattgagtta aaagctcctg
    12661 tatcacatat ctggtatttc aaagggattc catctcgtat gggattgact cttgatatga
    12721 gtcctcgtgc ccttgaagaa gtgatctatt ttgcggctta tgtggtcatt gatccaaaag
    12781 atacaccgct tgaaccaaaa tcattattaa cagaacgtga ataccgtgaa aaactacaag
    12841 agtatggtca tgggtcattt gtcgctaaga tgggtgctga agccattcaa gatctcttga
    12901 aacgtgtgga cttggcagct gaaatcgctg aattaaaaga agagttgaaa tctgcttctg
    12961 gtcaaaaacg gattaaagca gttcgtcgtt tagacgtcct tgatgccttt aacaaatctg
    13021 gaaataaacc agaatggatg gttcttaaca tcctgccggt tattccacca gatcttcgtc
    13081 cgatggttca attggatggt ggccgttttg cggcatcaga cttgaatgac ttgtaccgtc
    13141 gtgtgattaa ccgtaataac cgtttggcac gtttgttaga acttaatgcc cctggcatca
    13201 ttgttcaaaa tgaaaaacga atgcttcaag aagccgttga tgctttgatt gataatggtc
    13261 gtcgtggtcg tccaatcact ggaccaggaa gtcgtccatt gaaatcattg agccacatgc
    13321 ttaaaggtaa acaagggcgt ttccgtcaaa acttgcttgg taaacgtgta gacttctctg
    13381 gacgttccgt tatcgctgtt ggtccaaccc ttaaaatgta tcaatgtggt gtcccacgtg
    13441 aaatggctat cgagcttttt aaaccatttg taatgcgcga aattgttgcc aaagaatatg
    13501 ctggtaacgt taaagccgct aaacgtatgg ttgaacgtgg cgacgaacgc atctgggata
    13561 tcttagaaga agttatcaaa gaacacccag tcctacttaa ccgcgcaccg acccttcaca
    13621 gacttggtat tcaggctttt gaaccggttc ttattgacgg taaggcactt cgtcttcacc
    13681 cacttgtgtg tgaggcctac aatgccgact tcgatggaga ccaaatggcc atccacgtgc
    13741 cactttcaga agaagcacaa gctgaagctc gtcttttgat gcttgctgca gagcacatct
    13801 tgaaccctaa agatggtaaa ccagttgtta ctccatctca ggatatggtt cttggtaact
    13861 actatcttac gatggaagat gctggtcgtg aaggcgaagg tatgattttc aaggataaag
    13921 acgaagctgt gatggcatat cgtaatggtt atgctcatct tcatagtcgt gtgggtatcg
    13981 ctgttgacag catgccaaac aaaccttgga aagacagtca aagacataaa atcatggtga
    14041 caactgttgg taagattctc tttaacgata tcatgccaga ggaccttcct tacctccaag
    14101 agccaaacaa tgccaacttg acagaaggaa cacctgataa atacttcctt gaacctggtc
    14161 aagacatcca agaagtgatt gatcgcttag acatcaatgt gccatttaag aagaaaaacc
    14221 tcggtaacat cattgcggaa accttcaaac gtttccgtac aacagaaaca tcagccttcc
    14281 ttgaccgctt gaaagacctt ggttactacc attcaaccct tgccggtttg acagtgggta
    14341 tcgctgacat cccagttatc gataacaaag cagaaatcat tgatgctgct caccatcgtg
    14401 ttgaagaaat taacaaagcc ttccgtcgtg gtttgatgac agatgatgac cgttatgttg
    14461 ccgttacaac aacatggcgt gaagctaaag aagcccttga aaaacgtcta attgaaacac
    14521 aagatcctaa gaacccaatc gttatgatga tggactcagg agctcgtggt aacatctcta
    14581 acttctcaca gcttgctggt atgcgtggtt tgatggctgc tcctaacgga cgcatcatgg
    14641 aacttcctat cttgtcaaac ttccgtgaag gtttgagcgt tttggaaatg ttcttctcaa
    14701 cccacggtgc acgtaaaggg atgaccgata cggcccttaa aacagccgac tcaggttatc
    14761 ttactcgtcg tttggttgac gttgcccaag atgttatcat tcgtgaggac gattgtggca
    14821 ctgatcgtgg tcttcttatc cgtgctatta cagatggtaa agaagttacc gaaacgcttg
    14881 aagagcgtct tcaaggtcgt tacacacgta aatcagtcaa acaccctgaa actggtgaag
    14941 tcttgattgg tgctgaccaa ttaatcactg aagacatggc tcgtaagatt gttgatgcag
    15001 gtgttgaaga agtgaccatt cgttctgtct ttacctgtgc gactcgtcat ggtgtctgcc
    15061 gtcactgtta tggtatcaac ttggcaactg gtgatgctgt tgaagtgggt gaagcagttg
    15121 gtactattgc tgcccaatct atcggtgagc ctggtactca gcttaccatg cgtaccttcc
    15181 acacgggtgg tgtagcctca aataccgata tcacacaggg tcttcctcgt attcaagaga
    15241 tctttgaagc acgtaatcct aaaggggaag cggtcattac tgaagtgaaa gggaatgtcg
    15301 tcgagattga agaagatgcg tcaactcgta ccaagaaagt ctacgttcaa ggaaaaactg
    15361 gcatgggcga atatgtcgta ccatttacag cacgtatgaa agttgaagtt ggcgacgaag
    15421 ttaatcgtgg agctgccctt acagaagggt caattcaacc gaaacgtctc cttgaagtgc
    15481 gtgatacctt gtcagttgaa acgtaccttc ttgcagaagt acaaaaagtt taccgtagcc
    15541 aaggggtaga aatcggagac aaacacgttg aggtaatggt tcgccaaatg cttcgtaaag
    15601 ttcgtgtcat ggatccaggt gatacagacc tccttccagg tacacttatg gatatttctg
    15661 atttcacaga tgctaacaaa gatattgtta tctctggtgg tattcctgcg acatctcgtc
    15721 ctgttcttat gggtattact aaggcttccc ttgaaaccaa ttccttctta tcagctgcat
    15781 ccttccaaga aacaactcgt gttcttacag atgctgctat ccgtggtaag aaagaccact
    15841 tacttggtct taaagaaaat gttatcattg gtaaaatcat tccagctggt actggtatgg
    15901 cgcgctaccg taacattgaa ccacaagcga tgaatgagat tgaagtgatt gatcatacag
    15961 aagtctcagc agaagccgtt tttacagcag aagcagaata atctcatgaa agagtcctta
    16021 ggggctcttt tttgtctgag tttgttggca gtaaaaagca ttgacaatca gtcttagtcc
    16081 caatgagcag atgtttttca aaatacttat gatttagcta taataatgca taagaggaat
    16141 aggtaatgtg ttatgtatca agtaattaaa atgtatggtg attgggagcc ttggtggttc
    16201 atcgatggat ggcaagacga tattatagat gagcaacaat ttagtgactg gcaagaagcg
    16261 cttgattatt ttaatcaaga atggcagcgc atgaaagcta tttttcctag ttatcatagt
    16321 caaaagaatt tgttagctac tttttgggaa aaagaagata aaagatggtg cgaggactgt
    16381 gacgaagatt tacagcagtt tcattctctt ttactcctta aaaataaaga tattgtacca
    16441 agcaataatt atatccctga atttgaacaa cgaaatgatt caccacaggt agcttatctt
    16501 tgcaagttaa acctttaagt gtttgttaaa aacaaaataa gttaaaagaa aatatcactt
    16561 cttctgatat tttctttttt tgtttacgaa taaatgagta aggaggaatt atggtacaag
    16621 cattagcaaa agctattcta gcaaaagctg aacaggttca ggcacaagat atttatattt
    16681 tgccaagagc agatcaatat gatctttttt tacgaatagg agatgaaagg agattagttg
    16741 atgtttatca gagcgatcgg atggctcctc ttattagtca ctttaaattc gttgcaggaa
    16801 tgatagttgg tgaaaagaga cgttgtcagg tgggttcatg tgattataag cttagtaaag
    16861 ataagcagtt atctttgcgc ttatctagcg tgggtgatta tcgcgggcaa gaaagcttag
    16921 tgattcgtct gcttcatcat caaaataaaa gtgtacatta ttggtttgat ggattgacaa
    16981 aagtagccaa tcaggttggc ggtagagggt tgtatttatt tgcaggacca gttgggtctg
    17041 ggaagacaac cttgatgtac cagctgattt cgagttatca tcaagaagca caggttatta
    17101 gtatagaaga tcctgtagaa attaaaaatc accagatttt acaattacaa gtgaatgatg
    17161 atattggtat gacttatgac aatttgatca aactgtcttt acgccatcga ccagatattt
    17221 tagttattgg tgagattcga gatagtcaaa cagcaagagc cgttattagg gctagtctaa
    17281 caggtgccat ggttttttca acggttcacg ctaaaagtat ctcgggtgtt tatgtaagat
    17341 tgttagaact tggtgtaacg aaagcagaac tgtctaattg cttagcatta attgcttacc
    17401 aaaggttact taatggagga gcattgattg actctactca aaacgaattt gaatattatt
    17461 cctcatcgaa ctggaatcaa caaattgatc agcttcttga ggcaggacat ctcaatccca
    17521 agcaagctaa gcttgaaaaa attatctagt aaacatcagc ataaattcat tcaattacta
    17581 gctaatcttt tatctacagg atttagcttc gcagaggtta ttgctttttt aaaaagaagc
    17641 cagttgcttc agctagatta tgttcttaaa atggaagagt ctttattaaa aggacaagac
    17701 ttagcagata tgttgtcggg tttaggtttt tcagatgcta ttcttactca aattagttta
    17761 gctgatagac acggtaatat tgaaacaaca ttagtagcga ttcaacatta cttgaaccaa
    17821 atggcaagga tcagacgaaa aactgttgaa gttatcacct atcctcttat tcttttactt
    17881 tttctttttg tgatgatgct agggttgaga cgctatttag tccctcaatt agaaactcaa
    17941 aatcagataa cttactttct taaccatttt cctgccttct ttataggttt ttgctcaggt
    18001 cttattttgt tgttcgggat ggtatggcta cgatggcgat ctcaaagccg cttgaaactc
    18061 tatagtcggc taagccgtta tcctttttta ggtaaactgt taaaacaata cttaactagt
    18121 tattatgcta gagaatgggg tacgttaata ggtcaaggtc ttgatttgat gactatttta
    18181 gacattatgg ccattgagaa atcctcacta atgaaagaat tagctgagga catcagaatg
    18241 agtctgcttg aagggcaagc ctttcacatt aaagtagcta cctacccttt ttttaaaaaa
    18301 gaattaagtt taatgattga atacggtgaa atcaaatcga aactgggggc tgagttggaa
    18361 atctatgccc aggaaagctg ggaacaattt tttagtcagc tttatcaagt gacacaactt
    18421 attcaaccag ctattttttt agtagttgct gtgacaatcg tcatgattta tgcggcaatc
    18481 ctattaccaa tttaccaaaa tatgggaggt attttttaag atgattaatc aatggaacaa
    18541 cttacgacac aagaagctaa aaggatttac tcttctagaa atgttattgg tgattcttgt
    18601 catcagtgtt ttgatgctat tatttgtgcc taatttaagc aagcaaaaag acagggttac
    18661 agaaacaggt aatgccgctg ttgttaaatt agtggagaat caagcagaac tatatgaatt
    18721 atctcaaggc tcaaaaccaa gtttgagcca gttaaaggca gatggtagta tcactgagaa
    18781 acaagaaaaa gcttatcaag actattatga caaacataaa aatgaaaaag cccgtcttag
    18841 caattaaagc ttttactttg cttgaaactt tactaagttt gtcagtgatg agtttcatta
    18901 tattgggatt gtctgtacca gtgacaaaaa gctatcaaaa agtagaagag catctgtttt
    18961 ttagccattt tgaacatttg tatcgacatc agcaaaagtt agccatatta cagcaaaaac
    19021 agcgcgtctt ggatatttct tcaacaaaaa ttgttacaga aggtaatagc ctaacagttc
    19081 ctaaatcaat aacagtgaat catccttatc ggttagttat tgatcagatg ggaggcaacc
    19141 attccttagc taaaattatt tttgacatga ctgatcgacg ctttaaatac caattttatc
    19201 tagggagtgg gaattatcaa aaaacaagtc aaagcttaca tagcccttga aagtatgatc
    19261 gcaacaggca tcctctttag tattgtcatt ctcgtcttaa gcagtttaca gcagagtcag
    19321 gctgctctaa cgtactatcg aaagcagcaa gaaaagctta atctagcctt gatggcagta
    19381 caaactagaa ctaaagagat aacattgaat ggttgtcata ttactatttt acgtacggat
    19441 agatacatta gtattcacga tgacgaagga gaagtgatga agattgagta aacaattaag
    19501 taacataaaa gcttttaccc ttctagaggc gttaatagcc ttactcgtga tatcagggtc
    19561 tttattggtt tatcaaggtt tgacccaaac cctccttaaa cgtagccatt atctagcccg
    19621 tcatgatcaa gacaattggc tcttattttc tcatcaattg cgagaggagt taagtggagc
    19681 aagattttac aaagtagctg ataataaact atacgttgaa aaaggaaaga aagtactagc
    19741 ttttggccaa tttaaaagtc atgattttcg aaaatcagct agtaatggaa aagggtatca
    19801 acccatgtta tttggaatat cacgtagtca tattcacata gagcagtcac agatttgcat
    19861 tactttaaag tggaaaagtg ggttagaaag gactttttat tatgcctttc aagactaatc
    19921 tcaaagcagg catccttttg tatgctatgt ttatggctag tatttttttg ctggttttac
    19981 aggtttacct ttctcaagtg acagctctac acaaggaata ccaagctcaa actgactatg
    20041 ttaaagcccg actgatagca gaaatagttt atcaagatca tagatataaa gcttctaatc
    20101 ctgtcttttt taaaggtggt caagtcattt gtcgagagcg aaaagagaga tggatgttaa
    20161 ttgttaagtt agatcagcaa cgacagtatc agtttgaata ccttaaaccc aaacaatata
    20221 gtcaataaat agtattgttg tcataaatcc ataaaatgat ccaatatata gtaattaaag
    20281 gtgacacttc ttttcatttc aagtgtaatt tggtatgata aggttatgac ttttgaaaaa
    20341 attgaagaag cttatcagct gctcttagag aactgtcaac taattgaaaa tgatctaaaa
    20401 acacatatat acgatgccat tgttgaacaa aactcctttt atttaggggc tgagggagct
    20461 agtcctcaag ttgctcaaaa tagtgataaa ctgaaagcct tgtgcctgac aaaagaagaa
    20521 tggcgtaagg cctaccagtt tctttttatt aaggcagctc agacggagca actccaagcc
    20581 aaccatcagt tcacaccaga tgctattggc ttcattctgc tgtatctttt ggaacaattg
    20641 agtgataaag atagcttaga ggtacttgag attggaagtg gaacagggaa cctagcccaa
    20701 acccttctca acaacacgag caagagcctt gattatgtag ggattgaact tgatgatctc
    20761 ttgattgatc tgtcagccag tattgctgag ataatggatt cttcagctca ttttattcaa
    20821 gaagatgcgg taaggcctca attactaaaa gaaagtgaca ttgtcatcag tgacttacca
    20881 gttggttatt atcctaacga tgatattgcc aaacggtaca aggtggctag ttcagataag
    20941 catacctatg cccatcattt attaatggaa cagtctttaa aatacttgaa aaaagacggt
    21001 tttgcgattt ttctggcacc agtcaattta ttgacgagcc ctcagagcca gttattgaaa
    21061 cagtggttaa aagattatgc tcaggtggtg accttgatta cgctaccaga ttctattttt
    21121 ggtcatccct caaatgccaa gtccattatt gtcttacaaa aacaaacaga ccacccaatg
    21181 gaaacctttg tctatccaat tcgggatttg aagcttgcag agaatattca tgattttatg
    21241 gaaaatttca aaaaatggaa actgagtaat gtcaattaat tgattttttg ttataataaa
    21301 aaagcatcac agaaaacgat ttcaagagag gttaaaaatg tcaaagacaa ttgcaattaa
    21361 tgcaggtagt tctagtttaa aatggcaact ttatcagatg ccagaagaag aagtgttagc
    21421 acaaggaatt attgagcgta tcggtctcaa ggattctatt tcaacagtta agtacgatgg
    21481 caaaaaagaa gagcaaattc ttgatattca cgatcataca gaagctgtta aaatcttatt
    21541 gaacgatttg attcactttg gaatcattgc agcttatgat gaaattacag gagttggaca
    21601 ccgtgttgtt gctggtggtg aacttttcaa agaatccgtt gtggttaatg acaaagttct
    21661 tgaacagatt gaagaattat ccgttttagc tccacttcac aatcctggag cggcggcagg
    21721 gattcgtgcc ttccgtgata ttttgccaga tattaccagt gtttgtgtgt ttgacacgtc
    21781 atttcacact agcatggcaa agcatactta cctttaccca attcctcaaa aatattatac
    21841 ggactacaag gttcgtaaat atggggcgca tgggacaagt cataaatatg tagcgcaaga
    21901 agctgctaaa atgcttggtc gtccattaga agaattaaaa ctaattactg ctcatattgg
    21961 aaatggtgtc tcaattacag ctaattacca cggtaaatca gttgatacct cgatgggctt
    22021 tacaccactt gctggtccta tgatgggaac acgttctggt gacattgacc cagctatcat
    22081 tccttattta attgagcaag acccagaatt aaaagacgct gctgacgttg tgaatatgtt
    22141 aaacaaaaaa tcaggtctta gtggggtgtc aggcatttct agtgatatgc gtgatatcga
    22201 ggctggttta caagaagata atccagatgc tgttttagct tacaatatct ttattgatcg
    22261 cattaaaaaa tgcattggtc aatatttcgc tgttttgaat ggagcagatg ctttggtctt
    22321 tacagctggt atgggtgaaa atgcaccatt gatgcgtcaa gatgttattg gtggcttaac
    22381 atggttcgga atggacattg atcctgagaa aaatgttttt ggataccgtg gtgaaatttc
    22441 aactcctgag tcaaaagtga aggttcttgt tatctcaaca gacgaggaat tgtgcatcgc
    22501 gcgtgacgtt gagcgtttga aaaatacaaa ataaaagaga ctaagttttc atagattaac
    22561 caagtaaggc aacactttac ttggtttttt atgaggttta tctgttagtt atggtgccta
    22621 ggtattagtt ctgatcagtc tccttgcttt ttgtaatctt gtgctaggcg atttggatgt
    22681 cagccttatt tagaagtttt taattgcttc aacgcttttc ttgtatgtgt ttatagagcc
    22741 caatgatcta aaagactatt tgataacggt ttatgatgag cgtaatcgtg cgattcgaaa
    22801 acagacacaa gtttactgct tttacctgat gattgttcta tttgttgcct tattcttttt
    22861 cttcccttgc ttaaccattc gagaccttgt ttcttataag ctagctttga tttttgctta
    22921 cctttacttg attatcagaa gtctggtggc taagaaaatg gaggcactag ggaaaataac
    22981 aactaatagt caaaaacctc cgtttgatac gagtcaggtt ctttgttaga tgacttgtct
    23041 aacggttgag tttcctgtct ggtcaacgga ggtgtttgta ttgttgtctg atttgtattg
    23101 gggcacttat tttacaagct tttagcctta tcgatggttt tgtcaatggc agagctgaca
    23161 gtagttgtga ggccaaggcg ttctaactcc attagaccag caatagttgt gccaccgggg
    23221 ctacaaatag cgtcaatgaa atcgtgcgga ctttgagaac tggtcttgag attgctggcg
    23281 ctagccaaga ctgtttgagt aacaatctcc agcgcctttg ctttaggcat gccattcttg
    23341 acgccagcct tagccaaagc ctcaataaag agataaatat aggcaggact tgaccctgct
    23401 aaagcggtaa aggtgtcaaa atccttttca ctaatatcaa atgtgctacc aaagctatct
    23461 gttaagtttc gaacacgtgc ttgtaattcc tgggacacca aagcatttcc cgttaaagcg
    23521 gtactgcttt ggagaatttg tgcattcata tttggcatga tacgtagcag cggaaggtct
    23581 tgtcctacga atgttgctag tcgttgaagg gaaatgcctg ctgccataga tataataggc
    23641 tgtttgaagt gaagcggttt gagtaccgtt tcaaatagtt gaggcttgat gcctaaaata
    23701 acaagatcaa cctggtcaat aaggtcttgg tgggacatag cataaggcag tgttaactgc
    23761 tctgcaattt ccttggaccg ttctaaagat gatcctgaaa tgataagttc atggggtgtt
    23821 tgtttaaggc ctttgatgat agcgctagcc attttgccaa caccaataat gccaattttc
    23881 attctgttgc tccttgtggg atattacggt taatcaggct aacgctagtt tagtaacgtt
    23941 taatcaagtc aacggttgag cgatccagtt ttttgataat ggcttgtaag aaggcttggg
    24001 cttctacgaa atcatccata gcgtagaggg tttgatgaga gtgaatgtag cgtgcacaga
    24061 ctccgatggt tgttgatggg acaccaccat tttgaaggtg tgcagcacct gcatctgtgc
    24121 ctcccttgcc acaatagtat tggaaattga caccagcgtc ctcagcagta gtcagtaaga
    24181 agtcgcgcat atctttgagc atgacatggc ctgggtcgta aaagcgcaat aaggtaccat
    24241 ctccgattgt tccaggattg ccataaatat caccagcagg cgaacaatct actgcgaaaa
    24301 agagttcagg gtcgaacttg gtggttgaga cgtgggctcc gcgcagacca acttcttctt
    24361 gaacgttagc acctgcaatt agggtgttgt taaggtcttg tccttttaac gcttcaagca
    24421 tttctgttat catgagaacg ccatagcgat tgtcccaagc ttttgaaata atattttttt
    24481 gattggctgt taggatcgtt tcagattgag ggacaataat atcacccggt gtaatgccaa
    24541 agctttcagc ttctgcctta tccgtaaagc caccatcaaa cacaatattt tcgatatttg
    24601 gtagactagc agagccattt gccccacgta aaaaatgggg aggtaccgat cctgaaataa
    24661 ggggaataac ttggccagtg cgtgtgtaaa gggtaaaccg ttgtgaactg acaacaagtg
    24721 ggttccaacc accgatacca accacgcgta gcgttccgtc aactttgata tcactgacca
    24781 taaaaccgac ttcgtccatg tgcgcagcta ctaaaatacg gggggctttt tcagctttac
    24841 tatctctgat accaaaaatg ccaccaagcc cgtctgtttc aacacggtca accagcgggg
    24901 ttattttggt gcgtaggtag tcacgaacgc tatgttcata gcccgcaatg ccatccagtt
    24961 cggtaacttc tttgattttt gagaataagt ctgtcatttt tcatctccat ttaaaaggtt
    25021 tcagaccagt tcaacgcggt catctcctta tattctacca ctttttaagt aagaatgggt
    25081 ttcacagaaa agaaaaatcc cagagactag agatctctgg aagaagtgtt tgtcttttgg
    25141 cgataacctg tttttttagg cagcaaggaa atcattaaaa tgataaagca caagctggtt
    25201 aataagaata gtagggcgct taggatgcga aaagactctt cactagcgaa aagtaaggat
    25261 aatggagtca taaggagaac cttccatttt aggttaatca gtatttttta tagcgtggtt
    25321 aaattaataa taaaccacac ctaatcaatg tacttttagt ttagttgttt ttactatttt
    25381 tgtcaataca taacagtaga aatctttagt tttcttattt cagatcgtcc aatttgatct
    25441 ttttatgata aaatgaggga tatgagtaaa aagaaaatag gtatgatttc aggtatcttt
    25501 ggatttagtt tagctattgg cctgggaata gttatcaaag attattgcca agacaggcag
    25561 cgccgacaaa tgacaaggga tttacgcacc tttttttcac ctttaggaca aatcgaagtt
    25621 ttatatatca atccttgtca ggtcaaacaa gattatattt caggtggggt tgttatgtca
    25681 aacggcaaac agtaccaatt cacctatcac agtcgacaaa ttagttttga ggaggacaag
    25741 ggatgatcag accgacttct tatgagtcat tagcggctct tattgaaaaa gaagataagc
    25801 tggtgttatt ttttacggca gactggtgtc cagactgtca atttatttat cctattatgc
    25861 cagaaattga agcagaactt acagatatga cttttatttg tgttaatcgt gatcagttta
    25921 tagaggtagc acaaaagtgg aatatttttg gtattcctag ttttgtcgtg attgaaaaag
    25981 gtcaggaagt agggcgtctg gttaacaaaa tgagaaagac aaaaactgag attatgcatt
    26041 ttttagctgc ttatcaataa gaaaagagga agaataaatg atttttgcat acaataaaga
    26101 acaagttggc gatgtcttga tggttatctt acaagacacc aaagatatca aacgtcaagt
    26161 agaacgaaaa ggcaaagtag cccgtgtttt tgcagaagaa agcggcaaaa cccttgcttg
    26221 gaatatcttt gaagtgtcaa gcttgattac tattgaaggc aatggacaga tttttttgac
    26281 agacgaggac cttgcaagat taaatgcaga gcttgccaag gaaggatttt cagaaaggct
    26341 tgaaccgact gtgggacctg tttttgtggt tggtcaaatt gttgagatgg tggctcatcc
    26401 agatagcgac catcttaata tttgtcaagt ggctattggt gaagatcaaa cggttcaaat
    26461 cgtagcgggc gcaccaaatg ctgcgcttgg tttaaaaacg attgttgcct taccaggtgc
    26521 tataatgcca aatggtagtc tgattttccc aggaaaattg cgtggtgaag aaagttatgg
    26581 tatgatgtgc tctcctcgtg agttggtctt gccaaatgca ccgcaaaaac gtggcattat
    26641 tgaacttgat gagtcagctg tggtaggaga agcttttgac ccagccaaac attggaaagg
    26701 ttagaaaaac cagctgaaat aagactgtat ttaactaaat gaccagaaaa aaaggattag
    26761 gagcccttaa tccttttttc ttatgttttc aaaaacgttt aaaatgaaac ttattttacc
    26821 acaattttta cgaataataa gataaggagg tcagtatgta taataaagtg atagcaatcg
    26881 gtcgtttggt agctaaacca gaattggtaa aaaccgctac ggataagcat gtagcacgtc
    26941 tctctttagc tgttaatcga agatttaaaa atgcttcggg agagcgagaa gcggatttta
    27001 tttcaattgt tgtttgggga aagttagcag aaactctggt ttcttatgct agcaaaggta
    27061 gtttgatgtc tattgatggc gaacttagga cccgcaagta tgataaagat gggcaagtgc
    27121 attatgtgac agaagttctc tgccaatcat ttcaactgct tgaaagtcgt gctcagcgcg
    27181 ctatgagaga aaataatgtt actaatgatc tagttgattt agtcttagaa gaagatactc
    27241 ttcccttttg atagaggcta atgcttctca tcagggttca gctgattact gaaatatatg
    27301 atgaggtgat atccgagcaa caaaagtgtg actagatact tctgataaaa ataaaaaaaa
    27361 caccttacga gtatgaacaa agtttcaagt gctagatgtt ggaactttgt tcatcatagg
    27421 aatagtaggg tgttttttag tgtattactt ctttttgttg ctagtgttaa ggtttacttg
    27481 cttacaagcg gttatcaggc cactagaact cttataataa atggagctct ttgagtttgg
    27541 tgtcaatcat ttttaagaca gtcgccaaat cttgtgggtt ttgaacgaaa tcaagggaat
    27601 tgccatcaat tttcattttt ggagagacct tgtagtcttc gtaccaggtt gggtattcac
    27661 cgtggacttg atggtaatat tgctcaagac taggattgcc gtcgacctgc tcaaaacttc
    27721 ggccacgttt ttcaatgcgc tcaagcattt tgtcaaaaga cacatcaatg tagatgagaa
    27781 gatcagggcg ttttttaggc atgccttcta gttcttctaa catgttggcg agaagttcct
    27841 gatagatgtc aagttctgtc ttagtgacat tgccattttt gtagttaagt tttaagaaga
    27901 gttcgtcttc aaaaatagag cggtcaagaa tgttgttatc ggcttgataa gcttctttga
    27961 tggacttaaa ccgtttattc aaaaaataaa tttgaagtaa aaatgcgtac tttttagggt
    28021 cttggtagta gaggtctagc acggggttat tatcaacagc ttcataaaaa acgtcagttc
    28081 ctaagtgctc tccaagtgca gcagcaagcg agctcttgcc ggccccaatt gttccagcta
    28141 gtacaatcaa catgcgtctc cttctaatat cattagcgta ctgttttgaa gatggcttca
    28201 acctcagcta gagtctcagc gcgtgaaaca gcaccacgaa ctttggcagc acctgctgtt
    28261 ccgcgaagat agtgtggcgc taagccccga aattcccgaa cagcaatggt ttcacctttg
    28321 aggttaatca ggcgtttgag gtggtctttg gcgatgtcta attttttggc aaagggaaga
    28381 tctggcaatt cttgaccagt ttcaaagaaa tgattgattt gggtaaaaag ataaggattg
    28441 ttcatggctg cgcggccaat catcacggca tctacaccga tttcttcaat cataaatttg
    28501 gcgtcttgca ccgaacgcac gtccccattt ccaataaagg gaatcttagt gatagcctta
    28561 gaaactcggg ctaatgtctc atggtcgcag gttcctgtat acatttgttc acgggtacga
    28621 ccgtgcatgg caagagcaga tacacctgcc gactcagcgg caagggcatt ctcaacggca
    28681 agtgaactat ccgcccaacc tgtacgcatt ttgacagtca gtggaatatc taaaacagac
    28741 gtgacttcct tgacaatgtg gtaaatctta tcagggtcac ggagccactt ggcaccagcc
    28801 tcgtttttga caactttatt aacagggcag cccatattaa tatcaacaat atcggccttg
    28861 gtattggttt gaatgaaatc agctgcacgt ttcaaccctt ctgcgtcacc accaaataat
    28921 tgaatggaca tagggtgctc attctcgtca atatggagca tgtgaagggt cttttcgttg
    28981 ttgtagagca gccctttttc ggaaatcatt tccataacca ccaaaccagc accaaattct
    29041 ttggcgatgg tacgaaaggc agaattggtc acgccagcca taggggcaag tacagtgcgg
    29101 tgggggattt ccacatcacc aatcctaaag gaagaattaa gctttgtcat tgatgagggc
    29161 ctccaaatca ttttcattaa attggtactt ggtaccacaa aattggcaaa caatctcagc
    29221 acccttatct tcgtcaatca tggcctgtaa atctgctttt ggcaaagtca ttagggctgc
    29281 ttcaaaacgt tctctagaac agtcacactg aaaactcaga ggttcttcag aaagacgctt
    29341 gtaaggttca tctccataga tggcctccaa aagggcatcc acatgatttt tggaagctag
    29401 taggtgagaa atggcaggca tttcttgcag gcgtttttca tagcgagcaa tctcttcttc
    29461 agaagctcct ggtagcacct gcaccataaa gccaccagca accttgacct tatcattttc
    29521 atctaaaagc acattaagtc cgattgcaga tggtgtttgc tctgattcgg ttaagtagta
    29581 ggcaaaatcc tcaccaattt ccccagtaat aagaggcgtt gttgaggtgt aagggttacc
    29641 tgtgccataa tcaataatcg tcacaaaatg accattcccc ataaaaggcc caacaaggac
    29701 ttcacctgtt gcggtctttt taatatcgac accagtattt tgaatgtaac ctttcacatg
    29761 tcctttggta tctgccacag agataatgtg tccaaaagaa gaatcaccaa tcactttgac
    29821 ggtgatttta ctatcgcctt tttgattagc cgccaaaatc tggttggcga tcaaggtacg
    29881 gccaagcgca acagtagacg atgacagcgt gttgtgtttt tcttgagcta atgcaaccgt
    29941 ctcagtgcta tcaaggacat aagccctaaa agcccctgat tgtgctattg atttaattat
    30001 tttatccata acttagatta tagcataaag tgtaaaactt gtattgacag gattgcttga
    30061 aaaatcaata cagatagaca gtaaaaaatc ccagagaatg actcgggatt aagttaaggt
    30121 gtggtctaaa gtcgcgcaat gtggtgacat ggtgcttatg ttaattgctt ggttaaatca
    30181 gcttggaatt tttcctcttt aacttgatac atcaattctt ggatagacag aatcgattca
    30241 tcaaaagata tttcagcaac agcaattcct tttgtaagtt catggtgaac aaaaggaatc
    30301 agttgactgt gagtgatgac caaatctggc tttaaatcag gaatttgata aacattatct
    30361 tgcaatagat aataggaatg aaaatcaatg cttttatccg agaaatacct tggaaaagaa
    30421 tccgttagga gatgagcatt gataaaatta ctggctacga aaacaacaac taaaggaggt
    30481 tggatatttc ttagactttg ctcgatatag tgacaaaaaa gatgaaaatg cttatggttc
    30541 aagtcacgct taccaggaag tttggccatc cactcttcga caattaactt taaggacgta
    30601 tagagttttt ggtttccttt atagtacgga gaaacgaata agttggtctc aggaataaaa
    30661 tgttgcagat taaacaagaa tgattttgaa aaaaacataa gagcttttac taaactagcc
    30721 ttttgctctt ttaggttagg taaaagagtg atgataggat ttaaaagcag gcgaaaagta
    30781 tcattttctt caaaaagttg acaacattgt ctgatatgct caggtgtcca ttgtaagctc
    30841 gcaaaagaat tattagcggt gatataaatt aaatagaggt agtccaaatc tcctgctgaa
    30901 aagtttagtt ggcagtaagt ttcgataata tcatggctac tttttttcaa agaatcatag
    30961 acaaaaagtt tttttaattg ttgaaaaatt ctggtttggg gaatagttac cgaaaattga
    31021 tgccgcttcc acgataaagc caataaaatg tcatagaaag aaaacgattc cgataaccaa
    31081 ggagaggttt taaggtgggt ggaactatgg gataaaaagc tatgaatagt gtttttgtct
    31141 tgctgcgtca agtcataaac tttaatgcca aacttactat atagcagagc gatgaggtaa
    31201 cggatgcgat attcctcacc gacaatcttg ttcttagaga gttttaattc aaagtttctt
    31261 aataaaggaa tcaatgcttc gcgcatccga taagctgagg agtttgataa aaaatgactt
    31321 cttgcaaaat ccgtaagggg acgagagtgg gaaccatttt ttattaaaaa cgctagtaat
    31381 tgtaagacat tagatgatgc atagagttgg taaagataag tttctttaaa aggatgtgta
    31441 aattggcaag atatcatcct tttttggatg gtcatagaca gactaccagg gaaaaaggca
    31501 ttcagttcct cacaataatg gtttagttgt aaaaaggtta agccagtttt ttctgctacc
    31561 tcagttattg gcaaataaga tgtcttaaaa aacaagataa ttaactgaca ttttgattcg
    31621 attgatgatt ccaagtattt ttctatcaag gaaagggacc tctcttccta aacttagaaa
    31681 gccaaataag tctttgataa gtgtattctc ctatttcaat tctatctaag ctaaaaatag
    31741 aaatcaaatc taatggtttt tggtgaaaag tcgaaacctt ttgaaatagc tttaaagcaa
    31801 tattttctca aaaaatcat
//
LOCUS       DATWEK010000019        29039 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.019, whole genome shotgun sequence.
ACCESSION   DATWEK010000019 DATWEK010000000
VERSION     DATWEK010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29039
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.019"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(105..344)
                     /locus_tag="VCR92_001058"
     CDS             complement(105..344)
                     /locus_tag="VCR92_001058"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268132.1"
                     /translation="MSDVKWISQITAYDVDKLEEFKLILNANEIISIAEDTFEIFDEE
                     TGNLAEHKGCEVNVRDCCYKVLNSYEEFIKAMETL"
     gene            complement(347..541)
                     /locus_tag="VCR92_001059"
     CDS             complement(347..541)
                     /locus_tag="VCR92_001059"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268133.1"
                     /translation="MWKITIHLTNDITITTHSNSEEKEILINDIAQGIFTGKAFLSSN
                     DVLINPRHILFVESVEKEEV"
     gene            complement(513..944)
                     /locus_tag="VCR92_001060"
     CDS             complement(513..944)
                     /locus_tag="VCR92_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003108694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268134.1"
                     /translation="MEFEFMLPRNTKLKKQNMVINSNDRFHRQAQAVMTRRIKALAMY
                     EVTAKKDKQMKPFSPERPCHLIVTVYKPTNRRLDTPNLYPTVKALVDGMTEAKIWTDD
                     NDNVIKSTKFQLGGLSGKKGYYRFVLTIEEVNNVENNNTFN"
     gene            complement(934..1212)
                     /locus_tag="VCR92_001061"
     CDS             complement(934..1212)
                     /locus_tag="VCR92_001061"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268135.1"
                     /translation="MKEMFFAVVVTVFGVVNIWLVNVQAKKIDELFERTRMLNKNLDM
                     FGDEVRDLNYNPAVQKGKREAEIQRLKGKLDFLEKEKNSDCDGVNHGI"
     gene            complement(1209..1592)
                     /locus_tag="VCR92_001062"
     CDS             complement(1209..1592)
                     /locus_tag="VCR92_001062"
                     /inference="COORDINATES: protein motif:HMM:NF021182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268136.1"
                     /translation="MTIPKFRVYDKVECMMITTSDYEDLSDLFCFLKADADTGYCSEL
                     MQSTGLIDKNGKEVFENDVIRDSDGFEGIVQYDKSYGMYGIAYLPTKSNGIDMTFEEL
                     KDKYWNTFEVVGNIYENPELVEEAK"
     gene            complement(1573..1920)
                     /locus_tag="VCR92_001063"
     CDS             complement(1573..1920)
                     /locus_tag="VCR92_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268137.1"
                     /translation="MSIDALKEKWDGIYAWNVKDGKVEPPKHTFPKAVKDRADYFAEM
                     FEDGMTLVGCLDCIFSNEKPDDYDWGASKDWLPKSKEFKEWESQGSSLAQCEIAIYLL
                     FDNWEDKDDDTKI"
     gene            complement(2181..2423)
                     /locus_tag="VCR92_001064"
     CDS             complement(2181..2423)
                     /locus_tag="VCR92_001064"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268138.1"
                     /translation="MNKKLIVLVGLALAVIGLNGCSESSNASSHGVYAYIPNDNRNCG
                     WERVEVKDYSFFERRTKIETTDGRKIIGYNITIVEE"
     gene            complement(2416..2634)
                     /locus_tag="VCR92_001065"
     CDS             complement(2416..2634)
                     /locus_tag="VCR92_001065"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268139.1"
                     /translation="MESENLIIGLVVMLAAFMCIAVGYDIGRHESKSEMTELKTELKD
                     AKAQIKLLEENQVIVYYADSWGGNYDYE"
     gene            complement(2644..3405)
                     /locus_tag="VCR92_001066"
     CDS             complement(2644..3405)
                     /locus_tag="VCR92_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HEP4268140.1"
                     /translation="MMDVQVFNNEEFGQVRTLEIDGVPYFVGKDVAEVLGYSDTNQAI
                     RSHVDEEDKLTRQFYGSGQKRNMVIINESGVYNLIFGAAKQSANTEIKEKAKAFKRWV
                     TSEVLPTIRKHGSYVAPTQTALSTEDAFIQLFQTQKEIKQEQAVMRDDIVYLKEEQPV
                     NPSINQDLTKERNKAVVKCLGGYDAPAYSDSKLRQKVFCQAARDFKELFKIPRYDLLK
                     KKDIERAYDYWQQWQPQTNLRLEIEQANKQLSLII"
     gene            complement(3402..3617)
                     /locus_tag="VCR92_001067"
     CDS             complement(3402..3617)
                     /locus_tag="VCR92_001067"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268141.1"
                     /translation="MTQEQFIVILFGILGFTYLVLFTRWANKKITEAKQAYQATLKYY
                     QDPETQRQITSHVLANNMLRNGEEVFK"
     gene            complement(3614..3841)
                     /locus_tag="VCR92_001068"
     CDS             complement(3614..3841)
                     /locus_tag="VCR92_001068"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268142.1"
                     /translation="MKEERVKAEIMCPFCGMYMVLKIKKHRKSVSCPGCRERLYLKKT
                     NDKGFYFRASEAYGMRKITREFEKLFEENSK"
     gene            complement(3851..4402)
                     /locus_tag="VCR92_001069"
     CDS             complement(3851..4402)
                     /locus_tag="VCR92_001069"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268143.1"
                     /translation="MAMEVTNKGYINFNNEYNKHDQNFTTASMSFANGKGEDGNYKHG
                     YIKVIAFGELGNVLYDNVGNLVTITGRYRQNEHEGNKYPQIIIDAINGYAPAKNQNNG
                     NFGQNQGYQNQGNFQNNGSFGNQQPQNAINGYQNPNQGNFGQPQGQQTSFFQGQTTQT
                     NPDFSRNFGNANPMDINEDDLPF"
     gene            complement(4380..4550)
                     /locus_tag="VCR92_001070"
     CDS             complement(4380..4550)
                     /locus_tag="VCR92_001070"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268144.1"
                     /translation="MMWLAWLLHDVGALLVCAFIAVYFKQPLWMFLALLFTSSVSREK
                     KEGSDNGDGSNE"
     gene            complement(4547..4714)
                     /locus_tag="VCR92_001071"
     CDS             complement(4547..4714)
                     /locus_tag="VCR92_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268145.1"
                     /translation="MKKYYVSGKIAALDLGAEVEASNPYAAAIKFNERYAPLLKFGVH
                     ELEVREVEEVE"
     gene            complement(4711..5727)
                     /locus_tag="VCR92_001072"
     CDS             complement(4711..5727)
                     /locus_tag="VCR92_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEP4268146.1"
                     /translation="MKDVTNNTLTEINVEFKPAVIKIDRESIEAQVADAVAKYSNREI
                     TAETYKEAYNERTTYNNLTKALEAKRKEIKGVFNLPYNDFEAWYKEKVLAPIDEVTKK
                     MTEGLNAIDEQERLLRVDTVRAAFEEKCELAQLDKSTFEDKYNSYSLKKYFKSGKFEL
                     KTATLEEIDQIVLEEHKAVREFEESKETIVEQAKDYELLPDAYVRYLEDGKSLVDVLK
                     IMKSDRDAIALRKEQAEARAKAEAERKAEIERLAQENANSQIKAYNAETGEILEGNTI
                     TPETQNTAENEPKFEPDKALTLDLRLTFPGGVKQAKMFKDFLEMNGIKYEQQNMIMEM
                     GFEG"
     gene            complement(5739..6407)
                     /locus_tag="VCR92_001073"
     CDS             complement(5739..6407)
                     /locus_tag="VCR92_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HEP4268147.1"
                     /translation="MENVTIYKKLLNIQKVLNVPKGQYNEFGGYSYRNAEDILNAIKP
                     LLWENECTAFFRKDVIEQVGDRYYLVATFDFVDVNTGEKITVEARAREEEKKKGMDAS
                     QITGSASSYARKYALNGIFLIDDAKDADTNEYQKQQKQGTNTKQQTQYINDNQLQQIY
                     NGINQLAQMTNQNPDIVASGILVRYNINDFRAVPSGYFNEVVNYIKSLMPQQNPNQIN
                     FNDL"
     gene            complement(6395..6541)
                     /locus_tag="VCR92_001074"
     CDS             complement(6395..6541)
                     /locus_tag="VCR92_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006532391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268148.1"
                     /translation="MTHGLFGDFDYDNWLSTYEDHEEVFQGDEDEAYDRWKEEQLEDQ
                     EWKM"
     gene            complement(6538..6768)
                     /locus_tag="VCR92_001075"
     CDS             complement(6538..6768)
                     /locus_tag="VCR92_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268149.1"
                     /translation="MKIELLHIVNGHRKFHIGFYDNIKDAVKALKRDVAINSAIDKPK
                     WDKKYNETNDIVRIDYGLKTCYYLMQAVEVNK"
     gene            complement(6768..7025)
                     /locus_tag="VCR92_001076"
     CDS             complement(6768..7025)
                     /locus_tag="VCR92_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014334623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268150.1"
                     /translation="MADLKQTILAEHKTLKRIEELQEFMHGTSTIAIGLHEAGIIEQP
                     EHKLMFFETMHVFSHILEDVLDGKDAAEAVGDTLFPDEDED"
     gene            complement(7035..7415)
                     /locus_tag="VCR92_001077"
     CDS             complement(7035..7415)
                     /locus_tag="VCR92_001077"
                     /inference="COORDINATES: protein motif:HMM:TIGR01446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEP4268151.1"
                     /translation="MELKELINNFEANFGRMLSPFELEDIQKLVKEDGYSIELINEAL
                     KIAVRNGKLFLNYVVGILVRMRSQGITNVEQLRVAEQLKQGSSKPVEVDNDFLEMLIA
                     AAELWDDDEESREHQISLYREFQK"
     gene            complement(7539..7793)
                     /locus_tag="VCR92_001078"
     CDS             complement(7539..7793)
                     /locus_tag="VCR92_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEP4268152.1"
                     /translation="MVILRNKENWRVYPEEIAKRSKDKVSAVRTGLKELEEHQYIRTY
                     KKGLGDKSGISYFRFCADRKITDEIFEQLKQQLDNELTQM"
     gene            complement(7893..8036)
                     /locus_tag="VCR92_001079"
     CDS             complement(7893..8036)
                     /locus_tag="VCR92_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268153.1"
                     /translation="MAKKHYKIIHVMADGTELEDITDYIIPAGHQVYNILKAINEKQL
                     EVS"
     gene            complement(8284..8499)
                     /locus_tag="VCR92_001080"
     CDS             complement(8284..8499)
                     /locus_tag="VCR92_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4268154.1"
                     /translation="MVNTQKLKGVIVEKGTTQQAVADSIGVARSTFYRKLKNGGTFSV
                     EEAVKIALAVPLTKEEAIDIFFGDVVA"
     gene            8653..9390
                     /locus_tag="VCR92_001081"
     CDS             8653..9390
                     /locus_tag="VCR92_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4268155.1"
                     /translation="MDIGGKLKQRRIEEKISAEELANKLGVSKSTIYRYEKGEIAKVP
                     TETLEKISKILNTSPAYFMGWSDIPNNTKSDIVVIYDKLNQIRQEKVLNFASDQLAEQ
                     EQENTVSSIFSKKEDDNEYITDYVQGLVAAGRGVFQNDNLYMEVKLKAEDVPEEYDTI
                     AKVAGDSMEPLIKDNDLLFIKVTSQIEPNEIGVFQVNNKNFVKKLKRDYDGRWYLQSL
                     NDKYEEIYLSENDDIRTIGEVVDIYRD"
     gene            9441..10181
                     /locus_tag="VCR92_001082"
     CDS             9441..10181
                     /locus_tag="VCR92_001082"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268156.1"
                     /translation="MAKKGNQKNSKLTIWVLGFILVCLIIYLLSIVMPIVLIGGIVGV
                     WYFTKKKPDTSKRNISAIVAVVGLLGSVFLTSNTLNAKKTSVPSVPSVSSVSYSSSKK
                     KKQKTEDTSASTIESSILKEVASSSSTEASSEESAPDITKDNMPAIIERVQQRLSEDG
                     FDMTGYNLTYDDTILYLVVPDETKYYDKTKLQQFADGFQNKVHSYFNGWALENNYNYN
                     RPPLLVIKTQSGDRIASETLSGSMKLKK"
     gene            10320..11756
                     /locus_tag="VCR92_001083"
     CDS             10320..11756
                     /locus_tag="VCR92_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEP4268157.1"
                     /translation="MNKVAIYVRVSTTNQAEEGYSIEEQIDKLKAYCMIKDWSVYDVY
                     VDAGFSGSNIKRPAIQKLIKDTKRKVFDTVLVYKLDRLSRSQKDTLYLIEDVFLENKI
                     DFVSLLENFDTSTAFGKAMVGILSVFAQLDREQIKERMQLGKLGRAKSGKPMMWAKVA
                     YGYTYHIGTGKMTVNQSEAIIVKEVFSSYLNGRSITKLRDDLNEKYPKTPAWSYRTIR
                     QMLDNPVYCGYNKYKGQVYPGNHAPIISKEIYNQVQDELKIRQQKAYEHNNNYRPFQS
                     KYMLSGIAQCGYCKAPLKITLGTIRKDGTRFKRYQCVQRTPRKTKGATVYNNNEKCNS
                     GFYEKDDIEAYVLESISKLQTDSNCIDELFNDEPEKLDRDALNKEIETLSNKISRLND
                     LYINNLITLDDLKTKTDTLQSKIDILKEKLEKDPALERQKNKQKMLKKLYTKDIFKMD
                     YEEQKMLVRALINKVQVTADSIKILWKI"
     gene            complement(11773..12357)
                     /locus_tag="VCR92_001084"
                     /pseudo
     CDS             complement(11773..12357)
                     /locus_tag="VCR92_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(12505..13104)
                     /locus_tag="VCR92_001085"
     CDS             complement(12505..13104)
                     /locus_tag="VCR92_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEP4268158.1"
                     /translation="MAEEQVLNTHNASILLSAANKSHYPKDDLPEIALAGRSNVGKSS
                     FINTILGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGKMI
                     EEYLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNK
                     HESVVKKALNFDNSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            complement(13114..14343)
                     /gene="clpX"
                     /locus_tag="VCR92_001086"
     CDS             complement(13114..14343)
                     /gene="clpX"
                     /locus_tag="VCR92_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEP4268159.1"
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKID
                     DNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQA
                     LLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVR
                     ITKAAVEGKSKPVLETA"
     gene            complement(14473..14643)
                     /locus_tag="VCR92_001087"
     CDS             complement(14473..14643)
                     /locus_tag="VCR92_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268160.1"
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLGSLFLLNAFTNL
                     VNSIHAFYGTLF"
     gene            complement(14663..15160)
                     /locus_tag="VCR92_001088"
     CDS             complement(14663..15160)
                     /locus_tag="VCR92_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEP4268161.1"
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAVL
                     MGRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGG
                     NKVLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVT
                     ALKHK"
     gene            complement(15240..16079)
                     /locus_tag="VCR92_001089"
     CDS             complement(15240..16079)
                     /locus_tag="VCR92_001089"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEP4268162.1"
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAF
                     AEYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQT
                     RTIGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMF
                     DVRRVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNL
                     HIYDNQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFD
                     LAI"
     gene            16288..17463
                     /locus_tag="VCR92_001090"
     CDS             16288..17463
                     /locus_tag="VCR92_001090"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEP4268163.1"
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSV
                     APITEDIITLAASAADQILTDEDRSKIDMVILATESSTDQSKASAIYVHHLVGIQPFA
                     RSFEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIAL
                     LVTANPRILALNEDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQK
                     RENLQLSDFAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLIEAFQASITYSKQIGN
                     IYTGSLYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQA
                     LLDQRTRLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHRRIYHTNDKN"
     gene            17450..18727
                     /locus_tag="VCR92_001091"
     CDS             17450..18727
                     /locus_tag="VCR92_001091"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEP4268164.1"
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLP
                     IQTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG
                     GFKAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTI
                     HLEEKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESL
                     VTTSCEIPVRLLDHDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIAT
                     GNDWRAIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPT
                     VSIAHDLLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQTGHMKLHAKSLALLAGA
                     TQDEIAPLVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(18957..19946)
                     /locus_tag="VCR92_001092"
     CDS             complement(18957..19946)
                     /locus_tag="VCR92_001092"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEP4268165.1"
                     /translation="MTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLSDIDLST
                     HFAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSY
                     RLHEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTW
                     KKHLAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRG
                     GDRSYLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTV
                     LELVEKYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(19933..20946)
                     /locus_tag="VCR92_001093"
     CDS             complement(19933..20946)
                     /locus_tag="VCR92_001093"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEP4268166.1"
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAA
                     HIQLASDMFSHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGK
                     KFGIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQT
                     LVAYTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQM
                     IQQVTASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHSAIYHPKL
                     VTLVAACQKQDAVAKSSGSGGGDCGIALAFNQNARDTLISKWQEADIALLYQERWEEN
                     DQP"
     gene            complement(20939..21883)
                     /gene="mvaD"
                     /locus_tag="VCR92_001094"
     CDS             complement(20939..21883)
                     /gene="mvaD"
                     /locus_tag="VCR92_001094"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEP4268167.1"
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFT
                     TTSVSFLPDTATSDQFYINGVLQNDEEHTKISTIIDQFRQPGQAFVKMETQNNMPTAA
                     GLSSSSSGLSALVKACDQLFDTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAI
                     YKVETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDEWVEQSAIDYQHMLTYLK
                     TNNFEKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMD
                     AGPNVKVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            complement(21865..22743)
                     /gene="mvk"
                     /locus_tag="VCR92_001095"
     CDS             complement(21865..22743)
                     /gene="mvk"
                     /locus_tag="VCR92_001095"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEP4268168.1"
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFP
                     ADKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRA
                     VFSYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIAL
                     NGYLVIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQL
                     MTQAHSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKIS
                     HRLKEEGAVNTWIQML"
     gene            complement(23036..24268)
                     /locus_tag="VCR92_001096"
     CDS             complement(23036..24268)
                     /locus_tag="VCR92_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEP4268169.1"
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRIL
                     HLISSNKGKLPGTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDR
                     EEAQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLA
                     VSVMLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNE
                     LVELMTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAED
                     FKSLVLKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIG
                     RRRKRAKLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFK
                     GTITVNYKNDAIVFTVVI"
     gene            complement(24277..24945)
                     /locus_tag="VCR92_001097"
     CDS             complement(24277..24945)
                     /locus_tag="VCR92_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP4268170.1"
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNA
                     YDIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKP
                     FSLKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFL
                     MLNQGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYC
                     LLEK"
     gene            complement(24948..25598)
                     /locus_tag="VCR92_001098"
     CDS             complement(24948..25598)
                     /locus_tag="VCR92_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEP4268171.1"
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETG
                     FKLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVD
                     LLKSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTI
                     AQDSWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE"
     gene            25818..27830
                     /locus_tag="VCR92_001099"
     CDS             25818..27830
                     /locus_tag="VCR92_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HEP4268172.1"
                     /translation="MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGAL
                     DNTGTAYTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANS
                     ALLQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEH
                     EASHQTIVIANVIDKKTNDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQ
                     NYEHYQFLDAAETIAKYAKELQEQHVHAIVVLAHIPATSKDGVVDHEMATVMEKVNQI
                     YPEHSIDIIFAGHNHQYTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFMTTPSAN
                     VIAVAPGIKTENSDIKAIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNL
                     VTTAQLTIAKKTFPTVDFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQM
                     TGQHIYDVLNQQYDENQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNGEEINLT
                     TTYTVVVNDFLYGGGDGFSAFKKAKLIGAINTDTEAFITYITNLEASGKTVNATIKGV
                     KNYVTSNLESSTKVNSAGKHSIISKVFRNRDGNIVSSEIISDLLTSTENTNNSLGKKE
                     TTTNKNTISSSTLPITGDNYKMSPIMTILALISLGGLNAFIKPSVY"
     gene            complement(27903..28313)
                     /locus_tag="VCR92_001100"
     CDS             complement(27903..28313)
                     /locus_tag="VCR92_001100"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEP4268173.1"
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGM
                     AANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITV
                     EYLDHNWRPKRLSLTGLTAQICQHELDHLEGILI"
BASE COUNT         8873 a         5845 c         4775 g         9546 t
ORIGIN      
        1 ctctgggttt gttttatctc tcagaaaata ccacttcagc catatgattt ctcgtctatg
       61 tattacagac aatctttcaa acttcgtctt tgccataact tcacctacaa ggtttccatc
      121 gctttaataa actcttcata gctattcaaa actttataac aacaatcacg cacgttaact
      181 tcacaaccct tgtgttccgc caaattaccc gtttcttcgt caaagatttc aaatgtatct
      241 tccgctattg atataatttc atttgcgttt aatatcagtt tgaattcctc aagtttatct
      301 acatcatacg ctgttatttg acttatccat ttaacgtcac tcatcttcaa acttcctctt
      361 tttctaccga ctcgacaaac aaaatatgtc gcggattaat caaaacatcg ttacttgata
      421 aaaaagcttt tcctgtaaat ataccttgtg caatatcatt tatcaagatt tctttttctt
      481 cactattcga gtgcgttgta atagtgatgt cattagttaa atgtattgtt attttccaca
      541 ttgtttacct cctcaattgt caatacaaat ctgtaatagc ctttcttacc actcaaaccg
      601 cccaactgaa atttagttga tttaatcacg ttatcattgt catcagtcca aattttagct
      661 tctgtcatac catcgactaa cgctttaacc gttggataaa ggtttggcgt gtctaatctt
      721 cgatttgttg gcttatacac cgtcacaatt aaatgacatg gtctctctgg actaaaaggt
      781 ttcatctgct tatctttctt agctgtaact tcatacatcg ctaacgcttt aatacgtctt
      841 gtcatgaccg cttgcgcttg acgatgaaat ctgtcattgc tgttgataac catgttttgc
      901 ttttttaact tggtatttct aggcaacatg aactcaaatt ccatgattta ctccgtcaca
      961 atcgctgttt ttctcttttt caagaaaatc taacttaccc ttaagccttt gaatctccgc
     1021 ttctcgtttt cctttttgaa cggctggatt atagttcaag tctcttactt cgtcaccaaa
     1081 catgtcaagg ttcttattca gcattcttgt acgctcgaat aattcgtcaa tctttttagc
     1141 ctgaacattg actaaccaaa tgttcacgac accaaacaca gtaacaacca ccgcaaaaaa
     1201 catttctttc atttcgcttc ctccacaagc tctggatttt cgtaaatatt gcctacaact
     1261 tcaaacgtgt tccaatactt atcttttaat tcttcaaacg tcatatcaat accgtttgat
     1321 ttagtaggaa gataagcaat gccatacatg ccatagcttt tatcgtattg aacaatgcct
     1381 tcaaaaccat cgctgtctct aataacatca ttctcaaata cttcttttcc attcttatca
     1441 atcaaacctg ttgattgcat gagttcgcta caatatccag tatcagcatc agcttttaag
     1501 aaacaaaaca aatctgacaa gtcctcataa tcacttgttg ttatcatcat gcattcaact
     1561 ttatcatata ctctaaattt tggtatcgtc atctttatcc tcccaattgt caaatagtaa
     1621 ataaatagct atttcacatt gtgctaagct agacccttgg ctttcccatt ctttaaattc
     1681 ttttgattta ggcaaccagt ctttagaagc tccccaatca taatcatctg gcttttcgtt
     1741 gctaaaaata caatctaaac aacctacgag tgtcattccg tcttcgaaca tttcagcaaa
     1801 atagtccgca cggtctttaa ccgcttttgg aaaagtgtgc tttggcggct ctaccttgcc
     1861 atctttaaca ttccaagcat aaatgccatc ccatttttct tttaaagcat caattgacat
     1921 aattagacct ccaactcctc aatagaaaca taaccaacat ctcttagtct ctctatttct
     1981 ttatctaatt cgctatcaaa cacaaaagtt ttcttgacca accttatttt tttatgctta
     2041 ccgcaagaac actgtagtct tgtatataac ttaatatctt gaccataagc tgaataagtc
     2101 ataacataat agccgacttt cttataaatg tgcttatgga ctgatttgat tcctaacatc
     2161 ctttcaacct cacctcaatt ctactcctct acaatcgtaa tgttgtatcc tatgattttt
     2221 cgcccgtcag tagtctctat tttggttctt ctctcaaaga aagaataatc ttttacctcc
     2281 acacgctccc agccacaatt tctgttgtcg ttaggtatat aagcatatac gccgtgacta
     2341 gacgcgttgc tactctccga acagccattc aagcctatta cagctaacgc taagcctact
     2401 agcactatta attttttatt cataatcata attacctccc caactatcag cgtaatacac
     2461 aatcacttga ttttcttcta aaagcttaat ttgtgcctta gcatctttga gttcagtctt
     2521 taactctgtc atttcggact tgctttcatg cctgccaatg tcgtatccaa cagcgatgca
     2581 cataaacgct gctagcataa cgactagccc aattattaaa ttttcacttt ccataatcgc
     2641 ctcctaaata atcaaagata gctgtttatt agcttgttca atctctaaac gtaaatttgt
     2701 ttgtggttgc cattgttgcc aataatcgta agcacgctca atgtctttct ttttcaacaa
     2761 gtcatagcgt ggaattttga acaactcttt aaaatctctg gctgcttgac aaaacacttt
     2821 ctgtctcaat ttgctatcag aatatgctgg cgcatcataa ccacccaagc atttaactac
     2881 tgccttgtta cgttctttgg tcaaatcctg gttaattgac ggatttactg gctgttcttc
     2941 tttcaaatag acgatgtcat cacgcattac agcttgctct tgcttgattt ctttctgcgt
     3001 ttggaacagt tgaataaacg catcctctgt gctgagcgct gtttgtgttg gcgccacata
     3061 gctaccgtgt tttctaatgg tcggaagtac ctcacttgtc acccaacgtt tgaatgcttt
     3121 agctttttct ttaatttcgg tgttagcgct ttgtttagca gcgccaaaaa ttaaattgta
     3181 aactcctgat tcgttgatga tgaccatatt acgtttttga cctgacccgt agaattgacg
     3241 ggtcagctta tcttcctcat caacatgact tctaatagct tggtttgtat cgctataacc
     3301 taaaacctct gctacgtctt tccctacaaa ataaggtact ccatcaattt caagtgtacg
     3361 cacttgacca aattcttcat tattgaatac ttgtacatcc atcatttaaa aacctcctca
     3421 ccatttcgaa gcatattgtt agctaaaaca tgacttgtaa tttgtcgttg tgtttctgga
     3481 tcttgataat attttaaagt tgcttgataa gcttgtttag cctctgtgat tttcttgttc
     3541 gcccatctag taaatagtac tagatacgta aatcctaaaa ttccaaataa gattacaata
     3601 aactgctctt gtgtcatttg ctgttctcct caaataattt ctcgaattct cgtgtgatct
     3661 ttctcattcc ataagcttct gacgctctaa aatagaaacc tttatcattt gttttcttaa
     3721 gatatagtcg ttctcgacat cctgggcaag aaacggactt tctgtgtttc ttgattttta
     3781 gaaccatata cattccgcaa aacggacaca tgatttctgc tttaactcgt tcttctttca
     3841 tgcaacacct ctaaaatggt aagtcgtctt cattaatgtc cattggatta gcattcccaa
     3901 agtttctgct aaagtcagga ttggtctgtg ttgtttgccc ttggaagaaa cttgtctgtt
     3961 gtccttgtgg ctgtccaaaa ttaccttgat ttggattttg atagccattg attgcgtttt
     4021 gtggctgttg atttccaaaa ctaccattat tttggaagtt gccttggttt tggtagcctt
     4081 gattttgccc aaaattgcca ttgttttggt tcttggctgg tgcatatcca ttgattgcat
     4141 cgatgataat ttgtggatat ttattgcctt cgtgctcatt ttgacgatag cgacctgtga
     4201 tagttaccaa atttccgaca ttgtcataca ggacatttcc tagctcaccg aaagcaatta
     4261 ctttgatgta gccatgctta taattgccgt cttcgccttt accatttgca aagctcatgc
     4321 ttgcggtcgt aaagttttga tcgtgcttgt tgtattcatt gttaaagtta atataacctt
     4381 tattcgttac ttccatcgcc attgtcgcta ccttctttct tttctctact tacgctgctt
     4441 gtaaacaata gcgccaaaaa catccatagt ggctgtttaa aataaacagc gatgaatgca
     4501 catacaagca aagcaccaac atcgtgtaat agccaagcta gccacatcat tcaacttcct
     4561 ccacttctct aacttccaac tcgtgcacgc caaattttaa aagtggcgca tatctctcat
     4621 taaatttaat cgctgccgca tatggattag aagcctctac ttcagcccct aaatccaatg
     4681 ccgcaatttt tccgctgacg taatattttt tcatccttca aaccccattt ccatgatcat
     4741 gttttgttgt tcatacttaa tgccattcat ctccaagaaa tctttaaaca ttttggcttg
     4801 tttaacacct ccaggaaacg tcaaacgcaa atcaagtgtc aacgctttgt caggctcaaa
     4861 ttttggctca ttttcagccg tgttttgtgt ctcgggtgta attgtattac cttccaaaat
     4921 ctctccagtt tcagcattat atgccttgat ttgagagttt gcattttctt gcgctagacg
     4981 ttcaatctct gctttacgtt ctgcctctgc tttagctcgt gcctcagctt gttctttacg
     5041 taaagcaatc gcatctctgt ctgatttcat gattttaagc acgtctacaa gtgatttgcc
     5101 gtcctctaaa taacgaacgt aagcgtctgg tagcaattcg taatctttag cttgctcaac
     5161 aattgtctct ttgctttctt caaattcacg tacagctttg tgttcttcca agacaatctg
     5221 atcaatttct tcaagagttg ctgttttaag ttcgaatttt cctgatttaa agtatttctt
     5281 caagctatat gaattgtatt tatcctcgaa agttgattta tccagttgag ctagctcaca
     5341 tttctcttca aaagcagcac gtactgtgtc aactcgtagc aatcgttcct gttcatcgat
     5401 tgcatttaag ccttctgtca tttttttggt cacttcatca attggcgcta atactttttc
     5461 tttataccac gcttcaaaat cgttataagg taaattgaaa acacctttga tttctttacg
     5521 tttagcttct aaagctttag ttagattgtt gtaggttgtg cgctcgttat acgcctcttt
     5581 ataggtttct gctgttattt ctcgatttga gtatttagca acggcatcag caacttgtgc
     5641 ctcgatactt tcacggtcaa ttttgatgac cgctggttta aattcaacat tgatttctgt
     5701 tagtgtgtta tttgttacgt ctttcatctt tatctccttt atagatcatt aaaatttatt
     5761 tgatttggat tttgttgtgg catcagtgat ttgatgtaat ttaccacttc gttaaaatat
     5821 ccgcttggaa cagctctaaa atcgttgatg ttgtaacgaa ccaaaatacc acttgctaca
     5881 atatctgggt tttggttagt catctgtgca agctgattga tgccgttata aatctgctgc
     5941 aattgattat cattgatgta ttgcgtttgc tgttttgtgt tcgtgccctg cttttgctgt
     6001 ttctgatatt cattcgtatc agcatcttta gcatcatcaa ttaagaaaat accgtttaag
     6061 gcatattttc tggcatagct tgacgcagaa cctgtaattt gcgacgcatc catacctttt
     6121 ttcttttcct cctcacgggc tcttgcctca accgtaattt tttcgcctgt atttacatca
     6181 acaaaatcaa atgtagctac tagataatat ctatcaccaa cttgctcaat gacatctttt
     6241 ctaaagaaag ctgtacattc gttttcccac aacaatggct ttatagcgtt caaaatatcc
     6301 tcagcattcc tgtagctata gcctccaaat tcgttatatt gacctttagg aacgtttaaa
     6361 actttttgga tattaaggag ttttttataa atcgttacat tttccattcc tggtcctcca
     6421 actgttcttc tttccaacga tcataagcct cgtcttcgtc accctgaaat acttcttcat
     6481 ggtcctcata cgtgcttaac caattatcat aatcaaagtc accaaataat ccatgtgtca
     6541 tttgttcacc tcaacagctt gcattaagta gtagcaagtc tttaaaccat aatcaatgcg
     6601 aacaatgtcg ttagtttcat tgtatttctt gtcccacttc ggcttatcaa ttgctgaatt
     6661 aatagctaca tcacgtttta gtgctttaac agcatctttg atgttgtcat aaaagccgat
     6721 gtgaaacttg cgatgaccgt taacgatgtg tagtagttcg attttcatta gtcttcgtcc
     6781 tcatctggaa acaatgtatc acctactgcc tctgctgcat ctttaccatc caacacatct
     6841 tcaagaatat gtgagaaaac gtgcattgtt tcaaagaaca tcaatttatg ttctggctgt
     6901 tcaataatgc cagcttcgtg taacccaatt gctatcgttg atgttccgtg cataaactct
     6961 tgtagttctt cgatacgttt caaagttttg tgttctgcta aaattgtttg ttttaaatct
     7021 gccattgtgt tctcctattt ttgaaattct ctgtacaagc taatttgatg ctctctgctt
     7081 tcctcgtcat cgtcccaaag ttcggcggct gctatcagca tttccaggaa gtcattatca
     7141 acttcaactg gtttgctact tccttgcttt aattgttcag caactctcaa ctgctcaaca
     7201 tttgtaatac cttgcgaacg catgcgaacc agaataccaa cgacgtagtt taagaatagc
     7261 tttccatttc gtacagctat cttcaaagcc tcgttgatta attcaataga gtaaccgtcc
     7321 tctttaacaa gcttttggat atcttccaat tcaaacggtg aaagcattcg tccaaaatta
     7381 gcttcaaaat tattaataag ttcctttaat tccattacac ccacttatta attgttagta
     7441 attatttatt attagtaatt atttattgtt agtaattatt aggtggtgat ttctcaactt
     7501 tgagaaactc aactttgaga aactcaagtt tgagttttct acatttgagt cagctcgtta
     7561 tctagctgtt gttttaactg ctcaaagatt tcatcagtta ttttcctatc agcacaaaac
     7621 ctaaagtaag atatcccgct tttatcacct aacccttttt tgtaagtcct tatgtattga
     7681 tgctcttcta attcttttaa acctgtccta acagctgaca ctttgtcttt tgaccgctta
     7741 gctatttctt ctggatacac tcgccaattt tctttatttc ttaaaatgac catcagtatt
     7801 cccttggctt taaaagaaag ctcatcatcg tccaagaact cattactaac agccgtgtag
     7861 tttgatgttg tatttctgaa agatgtattg catcaactca cctccaactg tttctcgttg
     7921 attgctttta aaatgttata aacttgatga cctgctggga tgatgtagtc agtaatatcc
     7981 tcaagttccg taccatcagc cattacgtgg attattttgt aatgcttttt agccatagtt
     8041 tctcctttct tgcttgagcc aaaacattca acgtgtctga aagtgttaaa ccaattaagc
     8101 ttgtaataag tacctcgctt aattgataat gttttcgttg ccagtttttt actagcattt
     8161 cttgtgtact attaagttcg ttcatgttat aatttagtta gttataattt gttaagcgcc
     8221 tatcggattg ccgtccgagg tgcttttttt gttttgataa actactgtcg ttatcagttg
     8281 catttatgcg actacatccc caaaaaaaat atcaatcgcc tcttcttttg ttaaaggaac
     8341 ggctaaagca atttttaccg cttcttcaac tgagaaagtc ccaccatttt ttagttttct
     8401 ataaaaagta cttctagcaa cgccaatact atcagcaact gcttgttgag ttgttccttt
     8461 ttccacaatt actcctttga gcttttgagt attaaccatt tttatttctc ctttccagtt
     8521 gcgttattgc aactttgtga ctttattata agacctattt ttttatttgt caacacaaaa
     8581 gtttcatttt tgcaattatt tttgttgcaa ttttgcaaag tctatattat actatttgac
     8641 aaggaggaaa ttatggacat cggaggaaaa ttaaagcaac gacggattga ggagaaaata
     8701 agcgcagaag agctggctaa taaattggga gtttctaaat ctaccatcta tagatatgaa
     8761 aaaggtgaga ttgcaaaagt ccctacagaa acattagaaa aaatttctaa aatcctaaat
     8821 acaagccccg cttattttat gggctggtct gacatcccaa ataatactaa atctgatatt
     8881 gttgtaatat atgataaatt aaatcaaata agacaagaaa aggtcttaaa ctttgctagc
     8941 gatcaacttg ctgaacagga gcaagaaaat actgtttctt ctatctttag caaaaaagaa
     9001 gatgacaacg aatacatcac cgactatgtt caaggtttgg tggctgctgg acgtggtgtt
     9061 ttccaaaacg ataatcttta tatggaagtt aaattaaaag ccgaagacgt gccagaagaa
     9121 tacgatacaa tcgctaaagt tgctggtgac tcaatggaac cattaataaa agataatgac
     9181 ttgttgttca ttaaagtaac tagtcagatt gagcctaatg agattggtgt attccaggtt
     9241 aataacaaaa actttgttaa aaagctaaaa cgtgactacg acggtagatg gtatttgcaa
     9301 agtttgaatg acaaatacga agaaatttac ctatcagaaa acgacgacat ccgaacaatc
     9361 ggagaagtcg ttgatattta ccgagattaa aaaactacgt gcaaaagact gaaccacgtt
     9421 aaaagctgga ggaggatttt atggctaaga aaggcaacca aaagaactct aaattaacga
     9481 tttgggttct tgggtttatc ctagtctgtc ttattatcta ccttttatca atcgttatgc
     9541 cgattgtttt aattggtggt attgttggtg tttggtattt taccaagaaa aagccagaca
     9601 ccagcaaacg taacatttca gcaattgtgg ctgtcgttgg attgttagga agtgtttttt
     9661 taacatctaa tactttaaat gctaaaaaga caagcgttcc tagcgtgcca tctgtttcat
     9721 ctgtaagtta ctcttcatct aagaagaaaa aacagaaaac cgaggacact tcagcaagca
     9781 ctatagagtc atcaattctc aaagaagtag caagttcatc aagtactgag gcatcctcag
     9841 aagaaagtgc gcctgatata acaaaagaca atatgcctgc cattattgaa cgtgttcaac
     9901 aacgtttgtc agaagatggc tttgatatga caggatataa tctaacttat gatgatacaa
     9961 ttttgtatct tgttgtacca gacgaaacaa aatactatga taagactaaa cttcaacaat
    10021 tcgctgacgg atttcaaaat aaagtccatt catactttaa tggttgggct ttagaaaaca
    10081 attataacta taatcgtcca ccgcttttgg ttattaaaac acaaagtggt gatcgcattg
    10141 ctagcgaaac actttcagga agtatgaaac ttaaaaaata aataaaaaat cctcatgttc
    10201 tccatcgcca aactttgaac atgaggaaag ataaaactac aagaaaaaca ggcattaaaa
    10261 agcccttttt cttgtaccca ttttatcatt tttcaacgat aattgaaaga ggtacaaata
    10321 tgaacaaagt agctatctat gtacgtgtat caaccacaaa ccaagccgaa gaaggctact
    10381 ctatagagga acagatagac aagctaaaag catattgcat gattaaagat tggagtgtat
    10441 atgatgtcta tgtagatgct ggtttttctg gttctaatat caagagacca gctatacaaa
    10501 agcttatcaa agacacaaaa aggaaagtct ttgataccgt tttagtctat aaacttgacc
    10561 gactaagccg aagccaaaaa gacacattat acttaatcga agatgttttt ttagaaaata
    10621 aaatagactt tgtcagtcta cttgaaaact tcgatacttc tacagctttt gggaaagcta
    10681 tggtaggtat tttatcggtg tttgctcaat tggataggga gcaaattaaa gagcgtatgc
    10741 aattaggtaa attagggcgt gctaagtctg gtaagcctat gatgtgggct aaagtcgctt
    10801 atggctacac ttatcatatt ggaacaggta aaatgaccgt taatcagtcg gaagctatta
    10861 ttgtaaaaga agtgtttagc tcatatttga atggacgttc aatcactaaa ttaagagatg
    10921 atttaaacga gaaataccca aaaacaccag cttggagtta ccgcactata agacagatgc
    10981 ttgataatcc tgtatattgc ggttacaaca aatacaaagg tcaggtatac ccaggaaacc
    11041 acgcgcctat tatttccaaa gaaatataca accaagtcca agacgagctt aaaattagac
    11101 aacaaaaagc atatgagcac aacaataatt atagaccgtt ccaatcaaaa tacatgcttt
    11161 ctggtattgc acaatgtggc tactgtaaag cgcctttaaa aataacatta ggcacaatca
    11221 gaaaagatgg aacacgtttt aaacgctatc agtgtgttca gcgtacacct agaaaaacaa
    11281 aaggcgctac cgtctacaac aacaatgaaa aatgcaactc aggattttat gagaaagacg
    11341 atatagaagc atacgtccta gagtctattt ccaagctcca aacagactct aattgcatag
    11401 atgagctatt taatgacgaa ccagaaaaac ttgatagaga tgctttaaac aaagaaatag
    11461 agacactctc aaataagatt agtagactca atgatttata cattaataat ttaattacgc
    11521 ttgatgatct aaaaacaaaa acagatactt tacaatcgaa aatagatatt ttaaaagaaa
    11581 agctagaaaa agacccagct ttagaacgac aaaaaaacaa gcaaaagatg cttaaaaaac
    11641 tatacactaa agatattttt aaaatggatt acgaagagca aaagatgctt gtcagagcgc
    11701 ttattaacaa agttcaagtg actgctgaca gtatcaaaat tttatggaaa atttaacaaa
    11761 tttagtatca ttcatttcaa tggtgtgcaa aatacgatta acttttcctt tgagaacaac
    11821 agcagataaa tgtcctgttt tttgattata tttgcctccg atctgagaag ctaatttctc
    11881 aaaagcttga tctaaaatca tttctaattc atggctagct ggcatactat tctcaataat
    11941 ttggcgttct ttactactca agtcaccaac aactaaatga ttttccttta atgtctttaa
    12001 taattcattt tggtgataag cagctaaacg tttgacaaaa atgtctcgtt caacttgaac
    12061 actaaaactc aagtcaacgt tgttattttt aactgttagt atcatctgag atgacgttaa
    12121 taaactatca tcaataagag ggctctgatg caaaccagta agacgtttag caaaatcatc
    12181 gcctaacttc tgatcaatgc ttgttgttcg ccagatacct tcaatagagc tattacgata
    12241 tcgaacacca aaaagtacag caagcaagat aagaaaaata ataaatacaa aaagggcatt
    12301 gcattgatgg cataacaatg actttccttt agagcgccct tgggctactt gtgtcatgac
    12361 tcatctcctt aatataaaat actagcatgt catcattaag gcgtcaagta aaatcggtaa
    12421 acctaactat gattttttat gttttcgata agaaaaacac cctctactga gaatgtttta
    12481 gcatagataa atcaacacct atcgctagac ctgctctaaa atagcatccc aagaatcatc
    12541 gataccaata cgttctaccg aagaaaatac tataaaagta tcagagttgt caaaattcaa
    12601 agctttcttg accacagact catgtttgtt ccatttgcca cgaggaatct tatctgcttt
    12661 ggttgccaca acaataacag gaatgtcata gtacttcaaa aagtcataca tctgaatatc
    12721 ttcttttgaa ggggcatgac gtaaatcaac caaactcacg actgcacgca gattgtctct
    12781 gctggttaag tattcttcga tcatctttcc ccatttggcc cgttcacttt tagaaacctt
    12841 ggcatagcca taaccaggga catccacaaa tctaagcttg tcatcaatat tgaaaaaatt
    12901 taatagttgg gtttttcctg gcttgcttga ggttcttgcc aaatttttgc gccccaatat
    12961 ggtattaata aaacttgatt taccaacatt tgaacgtcca gcgagggcaa tttctggcaa
    13021 atcatctttg gggtaatgag atttattggc agcactcaat aaaattgagg cgttatgggt
    13081 atttaagact tgttcttcag ccattatttc tccttaagct gtctctaaaa cgggttttga
    13141 cttgccttcg acagcagcct tggtgatacg cacttttgtg acatcttctt ggcttggaat
    13201 ttcaaacata atgtctaaca tcgtttcttc aataatagaa cgaagaccac gtgctcctgt
    13261 cttacgctca atggctttat tggcaatggc ttctaaggct tccttatcaa atgccaattc
    13321 gacgccatcg taagaaagaa gggcctgata ttgcttgacc agggcatttc ttggttctgt
    13381 caaaatttga atcaaatctg atgtgtttag ttgttcaagg gctgccacaa ctggtaagcg
    13441 gccaataaat tctggaataa gcccaaactt ttgaatatct tctgaaataa tttcttgcat
    13501 ataagaagca ttgtcatcaa ttttacggct gttttgacca aaaccaataa ctttttcacc
    13561 taaacgttgt ttaacaatct cctcgatgcc atcaaaagcc ccgccaacaa taaacaagat
    13621 attttttgta tcaatttgga tcatttcttg attagggtgc ttccgcccac cttgtggggg
    13681 aacacttgct accgtacctt caataatttt aagaagggct tgctgtacac cttcaccaga
    13741 tacatcacgt gtgatagata cgttctcacc ttttttagca atcttatcta tttcatcaac
    13801 ataaataata ccacgctctg ctcgttcgac attatagtca gcagcctgaa tcagtttgag
    13861 taaaatattt tccacatctt ctccaacata ccctgcttca gtcaaagaag ttgcatctgc
    13921 aatagcaaat ggtacattga ggcttttagc cagagtttgt gctaagaagg tttttcctga
    13981 acctgttggt ccaatcatca aaatgttgga cttttgtaaa tccacatcat cgtcatcacg
    14041 actttctgta aacgagacac gcttataatg attgtacaca gcaactgata aagcacgttt
    14101 agcacgatct tgaccaacca catattgatt taaaacatca aggagctctt ttggttttgg
    14161 aacttctgtc aaatcggcaa ggacttcttc agccaattct tcttttataa tttcttgtga
    14221 taaagctacg cattcattgc agatgaaaac attatttcct gcgataattt ttttaacgtc
    14281 atcctggctt ttaccacaaa atgaacagta tactttaata tcgttagttc tacttcctgc
    14341 catttcttat aattctctta ctttctctta tcttttactg aattttaata ttagtcaatg
    14401 tgttgtattg gtttttagtg attcttgctt gatagctaaa tcttcaccag tgctgtcttc
    14461 gcaagtcaca tctcaaaaca atgtaccata gaaggcgtga atactattaa ccagattagt
    14521 aaacgcattt aataagaaca gacttcctaa gccataacga ttctttttaa aagctgggat
    14581 ggcacaaaga acacaaatca cgcacaaaaa agccgtaaat actccaaaaa tactacgttg
    14641 catcgcttat catctcctca gactatttgt gttttaaagc agtaacggta aaatcataag
    14701 gatttttagc gtctcgagca tagaacgttt ggctttcttg cgtgaaatga ctaaaatcta
    14761 gatttggtcg gtaggtatct cctttaaaac gatgatggat aactgttttt atgatacgat
    14821 cgaaataacc attaaacgct tctaaaacct tattcccacc aatgatataa agtgttttat
    14881 cctgcgcatg gtaccactcc aagacttttt caatactagt cattgtcaac acctcatcta
    14941 cttgataatc tctatttctt gtcatgacaa gggtttgacg ttgaggaagt cttttgcaat
    15001 tcattccttc aaaagtcaca cggcccatta agactgcttg atgtagcgtt gtctttttaa
    15061 aatgttctaa ctcttttggt aaataccatg gtaacttacc cgcaacacca ataagccctg
    15121 cttcatcctc tgcccaaata gcaataattt cctttgtcat taattatttc cttcatttta
    15181 aactctattt attttaccaa atttatgaac aaaatgctca caaaaaatct aaataaagtt
    15241 taaatagcaa ggtcaaagtg caactgaggc ttcactggat cataattttg taattcaaaa
    15301 tcatctggtt taatatcaaa gaaattagtc ccatctggaa catttaaaac aagcttaggc
    15361 tgactagcaa ctggctgtcg ctttagtaat tcttgagcct gatcaaattg gttgtcataa
    15421 atatgtaaat tgttaacaaa ataaaagaac ttacctattt tccatccaaa atgtttagca
    15481 atcatcatct gcaaagcaac gtattgcatg gcattgatgt gatgagcaac taatatgtca
    15541 ttagaacgtt gcgtcaaact agcatctaaa taaagatctt cccctacacg tctaacatca
    15601 aacatgattt gaaaggcaca tggcaacaac ccttttgtct cctcaaatgc ttcatagtcc
    15661 cagagagaaa tgacattacg acgattccaa ggattttctg ctaattgctt tagtattttt
    15721 gagatgatat catgtttttt gactacagca ccataacgtt gcccaatagt acgtgtctgg
    15781 tcaacttccc attcattcca ataatgaaca ttatatttag cttctagcac atctaaactg
    15841 ttggactgat cttgatatat ccaaaataat tcctttatag cagatttaat tggaatgggt
    15901 cgtaaagttg tgatgggaaa ctctccttta gctaaatcat attcagcaaa cgccccagta
    15961 atatacttag aatgagctgt tcgaccatct ttatatttag gacgtgcttg ctcactcaat
    16021 gatccttcgt ttataatttt ttgaatatta gctttaaaaa tctggtcagc ttttgtcatc
    16081 tctaataacc tttctgtaag catacttcat actattctaa ctaattttac caaaaaatac
    16141 cagaataaat aaacatttga aaaacttcat gtggtcatga acattttaac tattaaagga
    16201 taaaacaaat aactttatca gtctaatttt gcagtaaaat gtgatagaat gggtaagact
    16261 ataaaaataa ctaaaagaag gacaaatatg acaattggaa ttgataagat tggttttgca
    16321 accagtcaat atgtcttgaa attggaagat ttagcgcttg cacgccaagt ggatccagca
    16381 aaatttagtc aagggctact cattgagtct tttagtgtgg caccaatcac tgaagacatt
    16441 attactttag ctgcttctgc agcagatcaa atcttaaccg acgaagatcg atctaagatt
    16501 gatatggtta ttttggcaac tgaatcgagt actgatcagt caaaggcatc agctatctat
    16561 gtacatcact tagttggtat ccagcctttt gcacgttcct ttgaagtaaa acaagcctgc
    16621 tatagcgcaa ctgctgctct agactatgct aaactgcatg tggcttctaa gccagattct
    16681 cgtgtccttg ttattgctag tgatattgct agatacggtg taggatctcc tggcgaatca
    16741 actcaaggct ctggtagtat tgctcttttg gtaactgcta accctcgtat tcttgctcta
    16801 aatgaagata atgtggctca aactagggat attatggact tttggaggcc taactatagt
    16861 ttcacacctt atgttgatgg tatttactct accaagcaat atctcaattg cttagaaacc
    16921 acgtggcaag cttatcagaa aagagaaaac cttcagttat ctgattttgc tgcagtttgt
    16981 ttccatattc catttcccaa gttagcccta aaaggtctaa ataacattat ggataacaca
    17041 gtacctcctg aacacaggga aaaactaata gaagcctttc aagcttctat tacttatagc
    17101 aaacaaattg gaaatattta tactggctca ctttatctag gattgttatc tttacttgaa
    17161 aatagtaaag tattacaatc tggagataaa attggttttt ttagctatgg ttccggtgcc
    17221 gtaagtgaat tttattccgg tcagttagtt gctgggtacg ataaaatgtt aatgactaat
    17281 cgacaagctt tactggatca acgaacacgt ctttccgttt ctaaatacga agaccttttc
    17341 tacgaacaag tccaattaga tgataatggt aatgccaatt ttgacattta cttaactgga
    17401 aaatttgctc taacagccat caaggagcat cgaaggatct atcataccaa tgacaaaaac
    17461 taatcttaac tggagcggtt tttcaaagaa aacattcgaa gaacgcctcc aacttatcga
    17521 aaaatttaaa ctacttaatg ctgaaaactt aaatcaactc aaaacagacg ttcttttgcc
    17581 tatccaaaca gctaatcaaa tgactgaaaa tgtcttagga cgattggctt tgccctttag
    17641 catagctcct gattttcttg tcaacggttc aacttatcag atgccttttg tcacggaaga
    17701 accttctgtt gttgctgcag catctttcgc agcaaaacta atcaaacgct caggtggttt
    17761 taaagctcaa accctaaacc gacaaatgat tggtcaaatt gttctttacg atatcgacca
    17821 aatagataac gctaaagccg ccatccttca taaaacaaaa aagctaattg cattggcaaa
    17881 taaagcttat ccttccattg ttaaaagagg tggaggcgct agaaccattc atttggaaga
    17941 aaaaggagag tttttgattt tctatctgac tgttgatacc caagaagcta tgggagcaaa
    18001 tatggtcaat actatgatgg aagctcttgt tcctgattta acaagactgt ctaaggggca
    18061 ttgtctaatg gcgattttat ctaattacgc aacagagtcg cttgttacta ctagttgtga
    18121 gattcccgtg cgccttttag atcacgataa aacaaaatcc ctacagttag ctcaaaaaat
    18181 agagctagcc agccgactag ctcaagtaga tccttaccgg gctactactc ataataaagg
    18241 tatttttaat ggcattgatg cagtggtaat agccacagga aatgactggc gtgctattga
    18301 agcaggggcc catgcttatg cctcaagaaa tggtagctat caaggactta gtcagtggca
    18361 ttttgaccaa gataaacaag ttctgcttgg ccaaatgacc ctccctatgc ctattgctag
    18421 taagggggga tctatcgggc ttaaccctac tgtttctatc gcacatgatc ttcttaatca
    18481 acctgatgcc aaaacattag cccaattgat tgcatctgtg gggttagctc aaaactttgc
    18541 tgcactaaaa gctctgacct catctggcat ccaaactggt cacatgaaac tacatgcgaa
    18601 atcattagct cttttggcgg gggcaaccca agacgaaatt gctcctttag ttaatgcttt
    18661 actagctgat aaaccaataa atctagaaaa agcacatttt tacttatccc agctaagaca
    18721 gtcttagatt taaacaacta atataaggca aacacccatg taaacaattg gtttacatgg
    18781 gtgtttaatc tttgtttcta tacatacaag tcttagaaat agtctccata acatactcta
    18841 tttactcatc tactctattc tgagtttgat gaggtattta taaatatttt atattatgtt
    18901 ctaaaaaagc tctatcatct ttgtagtagg tggcactatt gtagaggtga tgaagcctaa
    18961 ttaacctgct gcaagcgtcc atatagtaag tagtcgactc cctttaattc tttaatagtt
    19021 ttacagtcaa gagcacacat aatgattttt aattcttctt tccagccgtt aacgatagca
    19081 atcacacgct cggttgggta tttttcgacc aattctaaaa cggtgcgtga gagtcccact
    19141 gcacgtgctc ctaggacgaa acatttaatc atgtccaagg ggtgtctgac accacccgaa
    19201 gctaagattt ccacttggtc catcagtcct tgtgcattta gcaagcactg aacggtggtt
    19261 tgtccccaat cgtttaagta agagcggtct cctcctcttt gattttcaat ataggcaaat
    19321 gaggtccctc ctcttcctga aatatcaaag gtttgaatgc ctaggtcatg tgctagcttg
    19381 atactattga catccatgcc aaaaccaact tctttgagaa tgacaggaac tggtatttga
    19441 ctagcgtatt cagcgaggtg ttttttccag gtatgaaaga cgcgctcacc ctctggcatc
    19501 agcaactctt gcatcacatt cacatgaacc tgtaaaaaga ggggctgcat ttcttgaacc
    19561 gtttgttgtc ctagcgccac aggtttatct agaccaatat tcgtggctag tttcaagtta
    19621 tctgccacct catgtaaacg ataggaatcg tcgttaggat tttttaaagc agcgctataa
    19681 gaccctgtca ccatgacaat ccctgttgct gctgctactt tggccaattt ttcattgaca
    19741 gctttgcctt tttgacttcc tcctgtcatg gcattgatgt aaaagggaaa gtcgaagtct
    19801 tgcccggcaa aatgagtact gagatcaata tcagacaaat catagctagg taaggaatga
    19861 tgtatgagtt ctatgtcatc aaaagcatta taaggcgatt ggtacttgag ggcatatttg
    19921 atgtgatcat ctttacggtt ggtcattctc ttcccacctt tcttgataaa gtaatgcgat
    19981 atcagcttct tgccatttgg aaataagggt atctctggca ttctgattaa aggcaagcgc
    20041 gatgccacaa tctccaccac cagaacctga agatttagca acagcatctt gcttctgaca
    20101 agcagctacc aaggttacta gcttaggatg gtagatagct gaatgaagct cttttaggag
    20161 atgacttgct cctgctaaac ttttcttgag ttcttcctta tgaccttctt gcaaagctac
    20221 catagctgat tgcgttagct ggtaacttgt tcttaagaaa gctggggtaa tgctcgctgt
    20281 cacttgttga atcatctgcc ttgaaatagc aggtatttta gtccagccaa ccaaaaagtc
    20341 acaaggcagg gctggttgaa tgacttggat atggtaaccc caatctttga cgagaagttt
    20401 ttttaagggc atggtctgca gccagttact gacctgttct cggtcaaagg aggtataggc
    20461 gactaaagtc tggtaagcga tacaggcaat atcccccata gacccattat ctccttgctt
    20521 aagcaaggta taagccgcta gtttaaagag taactctggg gttaaagtga tctgataata
    20581 ggccgataag gcctttaagg ttaagagggt gacactacca cttgaaccaa tgccaaattt
    20641 tttgccatcg cgctccattt ttcccgttat aattagggaa aatggctcca gttggtcaat
    20701 tgactgtcct agataatcag caaaggtttt aaccgttgct tgaatcagtg cataagaggc
    20761 atcgggtgtc atgcccgctt tatgggaaaa catatctgaa gctaattgaa tatgggctgc
    20821 tgggctaatt tctgctgtca tcatcagtgg aataaagtga attaaggctt tttgtcctgg
    20881 tgttaagata gcatattcgc ctgtgaggta tagtttccca cctgtttgca cacaataatt
    20941 agacatctgg taaatccttt gtttttgaaa cgataatacg gtagttcttg ccaagtcgtt
    21001 ctgctagttg agccaagtct ttttctaaac ataggacctt cacatttgga cctgcgtcca
    21061 tggtaaaata acaagcaaaa ccttcttgac gcagttcttt cacagcctcc atagcctggt
    21121 aagactcttt tgttaggtaa gaaaagggag gattggctgt ctttgtcgtg gcatgcatgg
    21181 ccaaggcatt agcttctgtt aactgaccaa ctttctcaaa attattagtt ttgagatagg
    21241 taagcatatg ttggtaatcg attgccgatt gttctaccca ttcatcaaat gtagttgagg
    21301 tatcgcggca taacttcatg ccctctcggc tagaaattgg ctttttcgca gcatttaaga
    21361 ccagcataat catggccatt ttcaagtcag tctcaacctt gtaaatagca ccactatctt
    21421 tgtcccaagc agcaactggg ccaaaaaaag aacgagaaga tgatcctgag gcgaacttag
    21481 ccttttgagc taaagctttc tgatctagct gagtgtcaaa taattgatca caggctttaa
    21541 ccaaggctga taagccactg gaacttgatg ataaacctgc agctgttggc atattatttt
    21601 gagtttccat ctttacaaaa gcctgaccag gttggcgaaa ttggtcaatg atagtagaaa
    21661 ttttggtatg ttcttcgtca ttttgcaaga caccgttaat gtaaaactga tcactggttg
    21721 cagtatctgg taagaaggaa acgctggttg tggtgaacat gttttccaaa gtcaaagaaa
    21781 tgctagaggt cgaaggaatc atcttagctt gattctcttt tccccaatat ttgataatag
    21841 caatgttagc ataggatgtt acggttataa catttggatc cacgtgttta cggctccttc
    21901 ttcttttaat ctgtgactga ttttttcggc catgtctttg gtatctgcta gggcaatcat
    21961 acagccaccc aagccaccgc ctgtcatctt agcgcctaaa gcacctgctc ttagggcagc
    22021 ctccacaagt tggtcagctt tactgatgct aacgccaatg gcctttaaag cagagtgcgc
    22081 ttgtgtcatg agctgaccga tagccacctt atttttttgg ttaatcgctc tttcaagggc
    22141 ttgtgtcaaa gctcctagtt tagccagata gggcaaattc gtttcctcaa actgtgctac
    22201 cttattgacg gcctcacgtg tatgaccgtg aatccctgta tctgcaatga caagataacc
    22261 atttaaggcg atttcgatag tttcaaagcc aatgtttcgg ataaacttaa tggcatggtc
    22321 actaaggcat gtcttggcat ctaaaccact aggattggtg tgggcaataa tttctgcctt
    22381 gttgactaaa atttccaaca aatcatccga gaggggttct tgacaataag aaaaaacggc
    22441 tctaatagct gcaatagaaa cggctgccga agaccccata ccacgctttt gtggcacttg
    22501 tgaaacaatc tcataagcaa ttggttcttg tagtcgctgc aaataatcca aggcagcata
    22561 aatggctgtt gatagagtat cataaaaatc aaagaccaat ggcttatcag ctggaaaaat
    22621 atgacaaacc acctcaatat ctgttaaagg caaagcaata gctgggtagc catacacaac
    22681 agcatgctca cctatcaaaa tgatcttact gtgtgcctta ccatatccaa tgttttcatt
    22741 cattttttat cttttcatta ctaattcttc taaactttta ccttactatt ttacactaaa
    22801 tgattagaaa atgcgatgat atatcttttt aaaatcattt cttcactgaa attaacaata
    22861 aagactatct actcttttta ggatcataac aaaaattttc ttatttcaaa ctaccttctt
    22921 taatcactct tctactaaat taaacgttaa aaccagcctc atgggctggt taagcatcat
    22981 ttattacctt tgcctagaca ttattactag ctaaaggtac tgaaaaatgt ttaagttaaa
    23041 tcaccactgt aaaaacaata gcatcgtttt tataatttac agttatcgtt cctttaaata
    23101 acttaaccat actttctgcc atagataaac caattccata gcctttttct ttgctattat
    23161 gggattcgtc ttcacgataa aagcgttcaa aaaagcggct gtaatcaatg gattttcctt
    23221 ccaaataggt attagaaact tctaatttcg ctcgttttcg tcttcttcca atagtggtta
    23281 aagatacctt gaccaagcct ttaggatcac aatatttatt ggcattatca actaaaattg
    23341 tcacaagttc aaataatgac ttttcctccg ctttaatcat aatattcggc tgaatcgtca
    23401 aatcaaaacg tttaccatct ttcaaaacca gactcttaaa atcttcagct gcatcttgag
    23461 caatagctga aaagtctacc atatgtaata ccacatctgg ctgttcctcc aaacgagcca
    23521 aagtaatcat ttgattaatc aagcctgtca atcgcttcac ctgatcactt gtactcttgg
    23581 tccattctga ttctccagtc attaattcga ccaattcatt attggctgag ataatggcta
    23641 gtggtgtttt taactcgtgg cctgcattag taataaagcg acgctgcttc tcataatttt
    23701 ggacaaaagg tttgatgacc ataccggaaa aaagactcac taaaacaaca aaaaagataa
    23761 atcctccaaa ggccaacatc actgaaacag ctaataaatc tcctacacta cgaaaataaa
    23821 aggtagtatc taaaattaca accagttttt cttcatttgg cagctgagta atcaagtacg
    23881 aataaacact atcttggtga cggtaactgc ctttttcttc cccagactta gcaaaaagtc
    23941 tagcaaaata ttgggcttct tctctatcta aagctgaaat attagcagta ttagaagaaa
    24001 gtagatgtcc attagcatta aaaatgacac tataataccg aaactggctt aggctatctt
    24061 cagacagttt cgttccaagt cgtttagagc tttccgtagt gccaggtaat ttacctttat
    24121 ttgaggaaat taaatgtaaa atacggttaa tttcttgttg actttggtaa cagcgtgccg
    24181 tgttaataat accaacaatt gaacttaaaa taataaaaat ggcaatagaa gcaatcatga
    24241 taaaacgaat acggatacga ttaaacatgt cacctcctat ttttctaata aacaatagct
    24301 agtatcttta tcacctgcaa taatgacatt tgcttgaata gctaataatt tttgacgaag
    24361 ataagaaata taaacccaaa caatagaagt atcataatct tcttggtctg accaaacatg
    24421 ttggtaaagt gttttagtat ccaagtactt tccttgattt aacattaaaa aggccattaa
    24481 tttaccttct ttagaagcta atcgtatagc attaccggca ctcaattctt gctcattaat
    24541 atttaatgtg acaccagcaa attgtaatac ctgaggagta aaactttcta ctcgtctttc
    24601 catcgacctt aatctagcta aaagttcttt taatgagaac ggtttagtca gataatcatc
    24661 agctcccgca tctagtccag taacacggtc attaatttct gccatagccg tcagcataat
    24721 aatatgtgag caatttcctg aagcgcgaat ctcctttaaa gcttcaatgc cagacttaat
    24781 cggcatcatg atatctaaaa tcataatatc atatgcattg tctttagctt tatcaattgc
    24841 ctcttgaccg ttaaaaacca catcaacgtc ataaccttga tgagtcatgg cagttgtcaa
    24901 aacattagac atctgccatt cgtcttcagc taacaaaatt ttcatggtta ctcttcctcc
    24961 gtcgtttctt gaatcaattg acgaatggtt tgcatggtaa catcacaaga tgccaactcg
    25021 tctgcacaac gctttaactc tcttgtaatc atttctgcat tagcaacttg atgtttgtac
    25081 ttcatttgat gttccaagct agcccaagag tcttgagcaa tggttcgcaa ctgcacttct
    25141 ataaaataac atcctttttt ttcccctaaa atatctggaa aatgtgtttc taattccaaa
    25201 atgagatgat atgatctata gccattaggc ttggcattta aaatataatc tttttcagtg
    25261 ttaactgaca taccaggaat gcttttgagc aagtctacca tccgataaat atcatcaata
    25321 aaaccacaaa taatgcgaat accgatacta tctttaatga tttttaatgc agatttgctt
    25381 gttagaggaa gttgtttgcg ttgacatttt tcaatcatcg aagcttccga tttaatacgg
    25441 gatgtaaagt gttcgtatag tttaaaccct gtttcttttt tgcttttgat attctcagca
    25501 ataatcacat ctgttattgt ctgtagtacc aacggcaagt acacttcaaa tccgctatat
    25561 atagagctgg tagaataatg ttctagtctt tctttcatac gcttattata acaaattttc
    25621 tcaacaaatg cttaaatctc tacaatgatc ggttatcttt atttctaact atataactgt
    25681 aaacgatctt tatcgtttgt ttttaaatcg ctttcatata ttttttgtgc gttctttttt
    25741 aaaaatacca ttgaattaca aacgaaaaca tagtaaactt gatctataac gattacgtta
    25801 acttattagg agattttatg aaaaaatatt ttattttaaa aagtagtgta ttgagtatcc
    25861 tgactagttt tactctatta gttacagacg ttcaagcaga tcaagttgat gtgcaattcc
    25921 ttggcgtcaa tgattttcac ggcgctcttg ataataccgg aacagcttac acaccaagtg
    25981 gtaaaatacc aaatgctggg acggctgctc aattaggtgc ttatatggat gacgctgaga
    26041 tagacttcaa gcaagcaaat caagacggaa caagtatacg tgttcaagct ggagatatgg
    26101 tcggagcaag tcctgctaac tctgcacttt tacaagatga gcctactgta aaagtcttta
    26161 acaaaatgaa atttgaatat ggcactcttg gtaatcatga atttgacgaa ggactagatg
    26221 aatttaaccg tatcatgaca ggtcaagcgc ctgatcctga atcaacaatt aatgatatca
    26281 ccaaacaata tgagcacgaa gcttcgcatc aaaccatcgt cattgctaat gttattgata
    26341 aaaaaaccaa tgatatcccc tatggttgga aaccttatgc tataaaagac atagccatta
    26401 atgacaaaat cgttaagatt ggcttcattg gtgttgtgac tacagagatt ccaaatctcg
    26461 ttttaaagca aaactatgaa cactatcaat ttttagatgc agctgaaacc attgccaaat
    26521 atgctaaaga actacaagaa caacatgttc atgctattgt ggttttagct catattcctg
    26581 caacaagtaa agatggtgtt gttgatcatg aaatggctac ggttatggaa aaagtgaacc
    26641 aaatctatcc cgaacatagc attgatatta tttttgcagg acataatcat caatacacta
    26701 atggaactat cggtaaaaca cgtatcgttc aagctctctc tcaaggaaaa gcttatgcag
    26761 atgtccgtgg tacgctagat actgatacca atgattttat gacaactcca tcagcaaatg
    26821 ttattgctgt agcaccaggt atcaaaacag aaaattcaga tatcaaagct ataataaatc
    26881 atgctaatga tattgttaaa acagttactg aacgaaaaat cggaactgca actaattctt
    26941 caactatttc taaaacagaa aatattgata aagaatctcc tgtcggtaac ttagtaacaa
    27001 cagctcagct tactattgct aagaaaactt ttccaactgt tgactttgct atgaccaata
    27061 atggtggtat tcgaagtgac ctagttgtca aaaatgatcg gaccatcacc tggggagctg
    27121 cacaggctgt acaaccattt ggtaatatcc ttcaagtcat tcaaatgact ggtcaacaca
    27181 tttacgatgt cctaaatcag caatacgatg aaaaccagac ctattttctt caaatgtcag
    27241 gtttaacata cacttataca gataatgatc ctaagaactc tgataccccc ttcaagatag
    27301 ttaaggttta taaagacaat ggtgaagaaa ttaacttaac aactacttac accgttgttg
    27361 tcaacgactt tctttatggt ggtggtgatg gcttttcagc atttaaaaaa gctaaattaa
    27421 ttggagctat taacacagat actgaagctt tcatcacata tatcacaaat ttagaagcat
    27481 caggtaaaac tgttaatgct actataaaag gggttaaaaa ttatgtaact tcaaaccttg
    27541 aaagttcgac aaaagttaat agtgctggta aacacagtat cattagtaag gtttttagaa
    27601 atcgtgatgg caatatagtg tctagtgaga tcatttcaga ccttttgact tctactgaaa
    27661 acactaataa cagccttggc aaaaaagaaa caacaacaaa caaaaatact atctctagtt
    27721 ccactcttcc aataacaggg gacaattata aaatgtctcc tattatgaca atccttgcct
    27781 tgataagctt aggtggacta aacgctttta ttaaacctag cgtttactag taatcgatca
    27841 cccttatata atcaggcatc tttgccaaaa aaaacctaaa gcgtcctact ctaggttttt
    27901 tgttaaatta aaataccttc tagatgatct aattcgtgct ggcatatttg agcagttaag
    27961 cctgttaagc ttaatcgctt tggtcgccaa ttatggtcca aatactcaac agtaatctta
    28021 tcataccgct gtgttttgcg atagccagat aacgacaaac aagattcttt agtttggtaa
    28081 attccctttt tagaaaccat cacaggatta aacataacca aatcaataaa tcccatactc
    28141 acaataacaa tgcgcttttg ttcaccaatc atattggcag ccatcccaag acattcctgt
    28201 ctataaaagg ctaaggtatc ttgtaaatct tggccaatcc atagatcttc tttcttggcg
    28261 acttgcgctt tttgctgtaa taaaaaatga tctgttatga tttctctaat cattcttatc
    28321 tccttaaacc ttctttttaa ttcataaact acatgttcaa tggactatta tcaccatatg
    28381 atagacttag tatcatctgt ttaaaacatc aggtgattcc ttatttcaag atatcttggg
    28441 caactttatg aaattctgca atatgagtac caaataaaaa ttgacctgca tcagcagatt
    28501 gttgctaagt tctcatcaca atattatcga atttactgtc tgcttcttca aatgtctaag
    28561 agagatagtt attgctttgt aagattttca aaccagatac tgctttctct tgcatttgca
    28621 gccttaacag gtccaaataa aacacctgct gtttgaaatg ctttaatagc tgatatgttg
    28681 ttaatagtta gtattataaa ttttctgaat atttctgtca agtttttcag ttgacttaac
    28741 ttttttactt gatttttcct cacgtaataa tagaaaagaa gcgccataat gtaaactaca
    28801 ccccaaacgt tagacaaaaa aatctaacga tcggggtgtt tttgtatgac attaagctat
    28861 gaagataagc tagacattta gcgctaaaaa aaccgaggga actccgtttg aaagaagcat
    28921 ctctgaaaag aagaagacaa aaaaccatta taaagaatgg acaaagacga gctctgatta
    28981 gattttcttt taaggacggc taaagtgact cgttctacct actattatca tcgattatt
//
LOCUS       DATWEK010000020        28546 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.020, whole genome shotgun sequence.
ACCESSION   DATWEK010000020 DATWEK010000000
VERSION     DATWEK010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28546
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.020"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            12..755
                     /locus_tag="VCR92_001101"
     CDS             12..755
                     /locus_tag="VCR92_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP4268174.1"
                     /translation="MNILGNSIKEIRKSKKMTQKELAKLTGFKQNTISNHENGNRQLD
                     EVDIRKYAKALKIEPQQLFDYSSSPTNPQVELIPSTLQKINSTSSQLEHSRQIIVLDT
                     AETLLEQQKEIKNNEDTIAELFSYNYYDHAASAGTGQYLNDVQVEKIELPVDYDADFV
                     IPVYGDSMEPKYHSGDYVFVKLSVELTDGDIGVFEYYGDAYIKQLLINAEGAFLHSLN
                     QCGDYPDIPIDRDSDFRIIGEVMGSYRER"
     gene            768..1577
                     /locus_tag="VCR92_001102"
     CDS             768..1577
                     /locus_tag="VCR92_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEP4268175.1"
                     /translation="MDSKALNKQNLSRSKKILLNISDNPKNPKFYKLSRQELERAKIF
                     KTENLIKSQKYQRYKRGTIVFIHFGVNIGNEFSDSHFGIVLNKKDHPNNGKLTILPLT
                     SKNSKESLSINKEIFTSIMDDAEKTVQTVQNVLNLTTEVERIHHSLPVPPAFFQIKKE
                     NKYHDIWMKYYNRHDPKGIHVPVANITVRKWIQSDLDKINFLKKRYANYDKVSYAKLD
                     SITSVSKLKIAKPINDLDPVGKITLSKEIMDNIDKALARQLLSGQWGKLDN"
     gene            1827..2915
                     /locus_tag="VCR92_001103"
     CDS             1827..2915
                     /locus_tag="VCR92_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEP4268176.1"
                     /translation="MKIKSYKKENGETAYKFLLYAGYVNGKRKYIRREGFKTKQAARE
                     TLISLQAELDKPKSSMTFGVLTKQWLNEYEKTVQGSTYLKTERNINKHILPKLDKVKI
                     GDINPLLIQRLTEEWCNDLKYGGKILGLVRNILNLAVRYGYINNNPALPITPPKIKRK
                     RKMNNNFYTLDQLKQFLELVEKTDNIEKIALFRLLAFTGIRKGELLALTWDDLNGNTL
                     SINKAVTRTQVGLEIDVTKTKSSDRLISLDDETLEILQELHETFPTSTLMFQSESGGI
                     MTPSLPRKWLLQIIKGTDLPQITIHGFRHTHASLLFESGLSLKQVQHRLGHGDLQTTM
                     NVYTHITQSAIDDIGTKFNQFVTNKQLD"
     gene            3278..3898
                     /locus_tag="VCR92_001104"
     CDS             3278..3898
                     /locus_tag="VCR92_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEP4268177.1"
                     /translation="MTKKHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQ
                     AAHQDKRANFEKIKLATVDSSFTGGTSLEELISLFGEPSQHDPKTAGEVTIDAYTWQF
                     DQVTLTVNLYQNSSIVKTISNFTFARELGLSQKEYQQLQKGMSYEDVKKILTEPDNYS
                     QASSSDHQTLQAIWVSGLKTDTSGANISLVFENNQLTEMSQVGLEE"
     gene            complement(4155..6419)
                     /gene="glgP"
                     /locus_tag="VCR92_001105"
     CDS             complement(4155..6419)
                     /gene="glgP"
                     /locus_tag="VCR92_001105"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEP4268178.1"
                     /translation="MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTQIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLIIDEAIERDSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTEKHGFDFDEAVAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPH
                     LVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYDLYPEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFA
                     DDKAVHAKLAEIKFNNKLALKRYLKDNKGIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMENIYTFGKDSDTIINLYATASYVAKDYYDNHPAIKAAVNFIISPELLAFGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQDLWMTKVVHNIAKAGFFSSD
                     RTIEQYNEDIWHSR"
     gene            complement(6454..7947)
                     /gene="malQ"
                     /locus_tag="VCR92_001106"
     CDS             complement(6454..7947)
                     /gene="malQ"
                     /locus_tag="VCR92_001106"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEP4268179.1"
                     /translation="MNKRASGILMHISSLPGKFGIGTFGKSAFEFVDFLAETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDFELLVDDELLEAADLCDITFGTNPEAVDYA
                     QLFQVRRPLLEKAVRAFVAEQENVCKLEAFETASSWLTDFAEFMALKEYFNNKALQDW
                     DDETVIKRQEDSLNNYRELLAKKITYHKVCQYFFYQQWSALKTYANHKGIEIIGDMPI
                     YVSADSVEVWTMPELFKVDSDKKPLFIAGVPADGFSEDGQLWGNPTYNWSAHEKSNFA
                     WWIYRIQESFKLYDQLRIDHFKGFSDFWEIPAGDKTARNGHWASAPGIALFSAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDITSQSIDLPHYYDRNCVAYT
                     GTHDNEVVNGWYDNLSEEQVHFVNNYLHKHADESITKAMLRTIFASVCDTAILCIQDL
                     LDKDGKSRMNMPNTIGGNWQWRMLDGELNQDHKDYLIYLTDLYGRAR"
     gene            complement(8063..9082)
                     /locus_tag="VCR92_001107"
     CDS             complement(8063..9082)
                     /locus_tag="VCR92_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP4268180.1"
                     /translation="MVTIKDVAQKAGVNPSTVSRVLKDNRSISMKTKEKVRKAMADLG
                     YVPNVAAQILASGLTHNIGLVFPPITTSDRLSEPFFMEILSTITNEAKESHFTVSIAT
                     GISLDDLIEQVKLMHLQKRVDGFIILYSDQDDPVKKYLMTNNLPFVIVGAPQGDTNKT
                     TYIDNDNQLMAKTAVEHLYQKGHHNILFITDDLLSEVTSERYLGYLKGCFKRSLKTKP
                     MLLFDRKDPVSVEILMETISSFKATALVVVGDVLAIRMVQLLSFYDIKVPDDMSIITF
                     NNSNYAKLIHPYLTTFDINVENLGKMSFKQLLDIINSNEQNLSQTIFVPFSLKQRESV
                     RDISH"
     gene            9325..10572
                     /locus_tag="VCR92_001108"
     CDS             9325..10572
                     /locus_tag="VCR92_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEP4268181.1"
                     /translation="MKSWQKVIVGGASLTLASTLLVGCGSGSKDKKEAGADSKTIKLW
                     VPTGSKKSYADTIAKFEKDSGYTVKVVESEDPKAQEKIKKDASTAADVFSLPHDQLGQ
                     LVESGTIQEVPEKYNKEIAATSTDQALVGAQYKGKTYAFPFGIESQILFYNKSKLAAE
                     DVTSYDTITTKATFGGTFKQANTYATGPLFMSVGNTLFGENGEDVKGTNWGNEKGAAV
                     LKWIADQASNKGFVSLDANNVMSKFGDGSVASFESGPWDYEAAQKAIGKENLGVAIYP
                     KVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKTRN
                     IVPANKEVQSSEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDAFN
                     GKIKESDYLTKLQQFDKDIAATK"
     gene            10846..12207
                     /locus_tag="VCR92_001109"
     CDS             10846..12207
                     /locus_tag="VCR92_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP4268182.1"
                     /translation="MTQSNLTPNISVIEALKRGSWDIKLSSIIMGFANFANKQFIKGI
                     LFLISELIFLVAFVSQIIPAIRGLVTLGTQTQGMTTKTIDGINIQVAVDGDNSMLMLI
                     FGLASLIFCLVFAYIYWCNLKSARNLYLFKQKGQKIPNFKEDLATLTNGRFHMTLMAI
                     PLIGVLLFTILPLIYMICLAFTNFDHNHLPPKSLFDWVGLANFGNVLSGRMAGTFFPI
                     FSWTLIWAVFATVTNFFFGIILALLINAKGLKWKKMWRTIFVITIAVPQFISLLIMRN
                     LLNDEGPLNALLNKIGLINGSLPFLSDPLWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILLIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSEYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            12207..13043
                     /locus_tag="VCR92_001110"
     CDS             12207..13043
                     /locus_tag="VCR92_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP4268183.1"
                     /translation="MKNKRRFQLGLVYATLIILSIIWLFPIAWVILTSFRSEGTAYVN
                     YFIPKTFTLNHYINLFTNETFPFGKWFMNTLIVATFTCIISTFITVAIAYSLSRIKFK
                     FRNGFLKLALILNMFPGFMSMIAIYYILKALGLTQTLTALVLVYSSGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLAKPIIVYTALLAFMGPWIDFIFAQVILG
                     DATSKYTVAIGLFSMLQPDTINNWFMAFTAGSVLIAVPITLLFMFMQKYYVEGITGGS
                     VK"
     gene            13201..13998
                     /locus_tag="VCR92_001111"
     CDS             13201..13998
                     /locus_tag="VCR92_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP4268184.1"
                     /translation="MTSKITIKDIAREAGVSVATVSYVLNQRNDQKISEETRNKVLHI
                     SNLLNYTPNQAARALVTQQSNSVVLYYKYADSILARAEQLHTISFLSRLLHEQDYQLV
                     CLNEDSIEKFDWADLILTLDVDNDTFYKIGKLNFKPLIAIDSFVNDPLFFQINTDYAA
                     LKDQANQFFKDEPYTLLSLPITNRERYEHVSAFFPSLHIVNDLRELTYFEKENLLLID
                     ESLDQFFVNSSQKLYCPRFSPKKGQVILEAIEWAKKRQPDKKHNLLV"
     gene            complement(14114..14929)
                     /locus_tag="VCR92_001112"
     CDS             complement(14114..14929)
                     /locus_tag="VCR92_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEP4268185.1"
                     /translation="MPDKKQFPISYISHCLSARAMFASRAQFTWWQNLLIIVFLNALI
                     MIPVTLHYANMTTYPLERIVTKSLSPITDKTYQALTQGKIEKDTFQGQSLIRRDGELV
                     LAVLPTKVDLEQLASESTRQIIVTKKEWRFVTPDGKELRAHVRGQQQSLADLTTVKAV
                     KDFVNQQWYDSNKASVLGFLLLTFVLMVCVGTLIVIGLGAFFLTLTKRSRLFMIRNFS
                     EGLGLMVNCLAWPSLLAIALSFFIQDPVLIMNCQVFGTLLMLTWVFYKTQFRD"
     gene            complement(14951..15811)
                     /locus_tag="VCR92_001113"
     CDS             complement(14951..15811)
                     /locus_tag="VCR92_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP4268186.1"
                     /translation="MRKTYVSISMKRKRFFTQLLTYLYLISLVIVILFPILVTVSSAF
                     RPGNTTAFSFHFDGPWTLSNFKTLFQDTLYLRWYWNTLIVAFFTMLIQVTVITLTGYA
                     YSRYNFFGRKKSLIFFLVVQMVPTMAALTAYFVMAWLFNALNQYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVLPLVRPMIAVQSLWAFMGPFGDF
                     MLAKFLLRAQENYTVAVGLQSFITNDARNPKVTLFAAGAILIAVPISVLFFFLQKNFV
                     SGLTSGGTKG"
     gene            complement(15808..17115)
                     /locus_tag="VCR92_001114"
     CDS             complement(15808..17115)
                     /locus_tag="VCR92_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP4268187.1"
                     /translation="MVDNQRQQKPNKAMWLSVIPGLGQLYNKQIVKGGVLLVVFFLEL
                     LEIVVLGIPALTGFYSLGSVPMQDHSLFMLIKGAMQLITLVLFGIFHLVAMRDAKLVA
                     HQMNEGKKVPVTAKETLEAIYEKGFPYLLIIPAYLAMAFAIIFPVLVTLLIAFTNYDF
                     RHIPPYRLLDWVGLKNFLNILELSTFKTAFTSVLSWTLIWTLAATSLQIVIGIATAVI
                     ANQSFIRGKRLFGVIFLLPWAVPAFISIMSFGNFFNDSIGAMNVQVLPFIEKFLPFVD
                     FGIVSWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQAIPADLYEAATVDGATVLQK
                     FRHITMPMIFAVAAPTFISQYTFNFNNFSIIYLFNNGGPGTVGGGAGTTDILISWIYK
                     LTTQTSPQFSMASAVTLIISVIVISVSLITFKKFKAFDMEERS"
     gene            complement(17190..19325)
                     /locus_tag="VCR92_001115"
     CDS             complement(17190..19325)
                     /locus_tag="VCR92_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclomaltodextrin glucanotransferase"
                     /protein_id="HEP4268188.1"
                     /translation="MRELHIKTYKLLTKSAVLLGLISFPLTVSAADNASVTNKADFST
                     DTIYQIVTDRFNDGNTSNNGKTDVFDKNDLKKYHGGDWQGIIAKIKDGYLTDMGISAI
                     WISSPVENIDSIDPSNGSAAYHGYWAKDFFKTNQHFGTEADFQQLVKVAHQHHIKVVI
                     DFAPNHTSTAEKEGTTFKEDGALYKNGKLVGKFSDDKDKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNINPKVDQYMKEAIDKWLDLGVDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFVFGEWFSGHTDDDYDMTTFANNSGMGLLDFRFANAIRQLYTGFSTFTMRDFYKVL
                     ENRDQVTNEVTDQVTFIDNHDMERFATKVANNQTAVNQAYALLLTSRGVPNIYYGTEQ
                     YATGDKDPNNRGDMPSFNKESQAYKVISKLAPLRKQNQALAYGTTEQRWISDHVLVFE
                     RKFGNHVALVAINRDQTNGYTITNAKTALPQNSYKDKLEGLLGGQELIVGADGTISSF
                     ELGAGQVAVWTYEGEDKTPQLGDVDASVGIAGNKITISGQGFGNSKGQVTFGEISAEI
                     LSWSDTLITLKVPTVPANYYNISVTTADKQTSNSYQAFEVLTDKQIPVRLLINDFKTV
                     PGEQLYLMGDVFEMGANDAKNAVGPLFNNTQTIAKYPNWFFDTHLPINKEIAVKLVKK
                     DSIGNVLWTSPETYSIKTGHEAQTITIKK"
     gene            complement(19351..21054)
                     /locus_tag="VCR92_001116"
     CDS             complement(19351..21054)
                     /locus_tag="VCR92_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEP4268189.1"
                     /translation="MNVAGMLHIPDSRYCFAISQKELVIRLRVAKEDRGITVNLVHGP
                     KYGYHEFQEELEMSVAYTDHTHAYYETTLTLDDVRLAYIFKIEEEGQTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQVIPWTKDAVFYQIFVDRFNRGDWEKGDSYVNMGW
                     LEKPTPKSFAGGDLKGITEKLDYLKDLGITVIYLTPIFQSISNHKYDISDYYAIDPQF
                     GTKYDLQELIDLAHQMGIKIILDAVFNHASSDAVEFQDVLRYGKESKFFDWFMTHDEH
                     PSMDLVNYETFAGCNYMPKWNTSNRDVQDYLIEIGRYWIKEFCIDGWRLDVSDEVSHD
                     FWRRFRQAVKAEKADAILIGENWHDAYPYLAGDQYDGIMNYAFTKACLDYFAFETMTS
                     KQLAEKLSNILMRNTWQVNRMNLNLLDSHDTHRFFTQVKGSKDKLLAALALLFIFMGI
                     PCLYYGTEVAMEGGYDPDSRRGFPWDDAERDKDFFSKVKAIIALRQQPALQEGAISID
                     YDEDCLILKRSLGEQSISLVLNNGESAYSIKEGGQILTSNGVTKNKKQLLQDGYIVFS
                     N"
     gene            complement(21220..22479)
                     /locus_tag="VCR92_001117"
     CDS             complement(21220..22479)
                     /locus_tag="VCR92_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEP4268190.1"
                     /translation="MSWNWKKASVLGTLSLASVLPLTACVSGGGKGVKETDGKTIVVS
                     VDEGYVDYIKSIKGEFEKEHKVTVKVKKEGMMDTLDKLSTDGPTGASPDVFLAPFDRV
                     GGLGTEGQISEVTLGNSKEFDDTVKKLVTIDGKTYGAPDVIETLVTYYNKDLVPQAPK
                     SFTELEVLQKDSKFAFASEPGKSVGFLAKWTDFYYGYGLIAGYGGYIFGDKGTKPSDL
                     GLGNDGTVEGLNYAKQWYGTWPQGMQDTKKAGDFITEQFISKKAGVIIDGPWAASSFK
                     DAGVNFGVMEIPTLTNGKKYQPFAGGKAWVISNYSKGKTTAQKFLDYVTNAENQKRFY
                     DKTQEIPANLTARNYASKEGNELTKAVISQFESAQPMPNIPEMAEVWEPGANMFFNVA
                     SGKEEASKAAKEAAKTIKEAIEQKYAE"
     gene            complement(23088..24071)
                     /locus_tag="VCR92_001118"
     CDS             complement(23088..24071)
                     /locus_tag="VCR92_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEP4268191.1"
                     /translation="MVIIAVVIFFGVILGILIVEYGQKRSFSSWLVEKMFAYRKYKLS
                     KKVDNYKGVETQRNRNIPYHLDNPEEIVGFSTQEYDVNGIQVFIINDQKQSHQPVIYY
                     LYGSVYLRRPEKLHFKTVKHLIQLTNAKVVFPNFPKVPYATYQDVYPKLVEAYQQFCL
                     SNGPSQVSVIGDSSGGGMALAFAKYIRDTKTALQPKQLILISPWLDVSFKNQAYKDFE
                     AEEAYLDARRLRDIGELWAGGQGNMQLPYVSPLYGDCEDLPEITTFVGTKEIFYPDIM
                     SLHDQLTRQRIANQLIIAEKMIHAYVIFPIREAKQARKQIAELVLKTVEPT"
     gene            complement(24102..25352)
                     /gene="dltD"
                     /locus_tag="VCR92_001119"
     CDS             complement(24102..25352)
                     /gene="dltD"
                     /locus_tag="VCR92_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEP4268192.1"
                     /translation="MLKRLWLILGPLLIAFVLVVITIFSFPTQLDHSIAQEKANAVAI
                     TDSSFKNGLIKRQALSDETCRFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSHYYGMQQITNEMQKKKAIFVVSPQWFTAQGINPSAVQMYLSNTQVIEFLLKA
                     RTDKESQFAAKRLLELNPGVSKSNLLKKVSKGKSLSRLDRAILKCQHQVALREESLFS
                     FLGKSTNYEKRILPRVKGLPKVFSYKQLNALATKRGQLATTNNRFGIKNTFYRKRIAP
                     KYNLYKNFQVNYSYLASPEYNDFQLLLSEFAKRKTDVLFVITPVNKAWADYTGLNQDK
                     YQAAVRKIKFQLKSQGFHRIADFSKDGGESYFMQDTIHLGWNGWLAFDKKVQPFLETK
                     QPVPNYKMNPYFYSKIWANRKDLQ"
     gene            complement(25345..25584)
                     /gene="dltC"
                     /locus_tag="VCR92_001120"
     CDS             complement(25345..25584)
                     /gene="dltC"
                     /locus_tag="VCR92_001120"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEP4268193.1"
                     /translation="MSIEETVIELFDRLFMEDVSEMMDEDLFDAGVLDSLGTVELIVE
                     LESTFNIKVPISEFGRDDWNTVTKIVQGVEELQHA"
     gene            complement(25602..26858)
                     /gene="dltB"
                     /locus_tag="VCR92_001121"
     CDS             complement(25602..26858)
                     /gene="dltB"
                     /locus_tag="VCR92_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEP4268194.1"
                     /translation="MMMFFSHIPYMEPYGNPIYFVYLILAFLPVIIGIFKQKRLSTYE
                     TLVSLVFILFMFGGDHYQQLVAFLFYLLWQIISVFAYQKYREKANSAGVFYLAIAMAL
                     FPLIWVKVAPLTGPSSQTLFSFLGISYLTFKSIGMIIEMRDGTLQEVRLPDFIRFMIF
                     FPTFSSGPIDRFRRFQEDYHKLPERDDYFAMLNKAVMYLMLGFLYKHIISYCLGGILL
                     PLLENKALMVGGYFNKETILVMYVYGLNLFFDFAGYSMFAIGISYLLGIRTPENFNMP
                     FLSASLKDFWNRWHMSLSFWFRDYVFMRLVHLLIKHKTFKNRNVTSGVAYLVNMLVMG
                     FWHGLTWYYIAYGLFHGIGLIINDAWIRKKKEINRHRKKKGLSPLFQSRAFHVLCIVV
                     TFHVVMFSLLLFSGFLNDLWFNRPLH"
     gene            complement(26855..28393)
                     /gene="dltA"
                     /locus_tag="VCR92_001122"
     CDS             complement(26855..28393)
                     /gene="dltA"
                     /locus_tag="VCR92_001122"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEP4268195.1"
                     /translation="MIKDMIDSIEQFAQTQADFPVYDCLGEHRTYGQLKRDSDSIAAF
                     IDSLALLAKSPVLVFGAQTYDMLATFVALTKSGHAYIPVDVHSAPERILAIIEIAKPS
                     LIIAIEEFPLTIEGISLVSLSEIESAKLAEMPYERTHSVKGDDNYYIIFTSGTTGQPK
                     GVQISHDNLLSFTNWMIEDAAFDVPKQPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKELVADFKQLFTTIAQLPVGIWTSTPSFADMAMLSDDFCQAKMPALTHFYFDGEELT
                     VSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYI
                     IDEDGKELASGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTED
                     NILLYGGRLDFQIKYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIV
                     VKDGVKERFDRELELTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKIDIKTLINE
                     VNNR"
     gene            complement(28405..28545)
                     /locus_tag="VCR92_001123"
     CDS             complement(28405..28545)
                     /locus_tag="VCR92_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEP4268196.1"
                     /translation="MKNKSRMRGIAVFIGKTILFYLILMLLVYFFGYLGHGQSNFIYN
                     EF"
BASE COUNT         9266 a         5667 c         4811 g         8802 t
ORIGIN      
        1 ggaaaaatat tatgaatatt ctcggaaatt ctatcaaaga aattcgaaaa tccaaaaaaa
       61 tgacccaaaa agagttagca aaactaactg gatttaaaca aaatacaatt tctaatcacg
      121 aaaatggtaa tagacaactt gacgaagtag atattcgaaa atatgctaaa gcactgaaaa
      181 tagagccaca acagcttttt gactattcct cttctcccac aaacccccaa gttgaactca
      241 tcccatctac cctacaaaaa ataaactcta cttcttctca attagaacac agtagacaga
      301 taattgtttt agatacagct gagactttat tggaacaaca gaaagaaatt aaaaacaacg
      361 aagatactat tgccgaatta ttttcttaca actactacga ccacgcagct tcagctggta
      421 caggtcagta tctaaatgat gtacaagtag aaaaaattga gttaccagtc gattatgacg
      481 cagactttgt tatccctgtt tatggtgatt ccatggaacc gaagtatcac tctggggatt
      541 atgtatttgt taagctatcc gtagagctta cagatggcga tataggcgtc tttgaatact
      601 atggtgacgc ttatatcaaa cagttgctta taaacgctga aggggcgttt ttacacagtt
      661 taaatcaatg cggtgattat ccagatatac cgatagatag agatagcgac tttaggatta
      721 ttggtgaagt tatggggagt tatagggaga gataggcagg agcagaaatg gatagtaaag
      781 cattgaataa acaaaattta agccgtagca agaaaattct gttgaatatc tctgataatc
      841 cgaaaaatcc caaattttac aaattatcaa gacaagaact cgagcgcgct aaaattttta
      901 aaacagaaaa cttaattaaa tctcaaaaat atcagagata caaacgagga actatcgtct
      961 ttattcattt tggagtaaat atcggcaatg aattttccga ttcgcacttt gggattgtgc
     1021 tgaataaaaa agatcatccc aataacggaa agctaactat cttaccgcta acatcaaaaa
     1081 actctaaaga gagtctgtca attaacaaag agatttttac gagcataatg gatgatgccg
     1141 aaaaaacagt tcaaacagtt caaaatgtgc taaacctaac aactgaagta gaacggatac
     1201 accactcgtt accagttccc ccagcgtttt ttcagattaa aaaagaaaat aaatatcatg
     1261 atatatggat gaaatattac aataggcatg accctaaagg gattcatgtg cccgtagcaa
     1321 acattaccgt ccgaaaatgg atacaatcag acttagacaa aattaacttc ctcaaaaaaa
     1381 gatatgcaaa ttatgacaag gtgtcctacg ccaagctgga ctcaatcact tctgtcagta
     1441 aactaaaaat cgctaaacca attaacgatc ttgaccctgt cggaaaaata acattgtcta
     1501 aagaaatcat ggacaacatt gataaagctc tcgcaaggca gttattatct ggccagtggg
     1561 ggaaacttga caattaaata tcactatgtt agaattaagg tgtaatcttg gtagcctcgc
     1621 taccactgaa acattatttt ggagtgtcca actccactgt gagcgcctgt tttcgaataa
     1681 gcgctctttt ttgttttaaa aaaataaaaa agccccacgc tctcaaagtt tggcgactct
     1741 gagcgtgagg caagacagta taagaaacaa ccattaaaaa ggtcattttc ttgtacctat
     1801 tttatcaaat tgaaagatgg tatgcaatga aaattaaatc atataaaaag gaaaatggtg
     1861 aaactgctta taaatttctt ttgtatgccg gttatgttaa tggaaagaga aaatatatta
     1921 ggcgagaagg tttcaaaact aagcaggctg caagggaaac cttaattagt ttgcaagctg
     1981 aacttgataa acctaaatca agtatgacgt ttggtgtgtt aactaaacaa tggctaaacg
     2041 aatatgaaaa aactgtccag ggcagtacct acttaaaaac agaaagaaat attaataaac
     2101 atattttgcc aaaacttgat aaagtgaaga ttggagacat caacccacta cttatccagc
     2161 ggcttactga agaatggtgc aacgatttaa aatatggagg aaaaattctt gggcttgtta
     2221 ggaatatctt aaatctagct gttagatacg gatatatcaa taacaatcca gctttgccaa
     2281 ttacacctcc aaaaataaaa aggaaaagaa aaatgaataa taatttttat acacttgatc
     2341 aacttaaaca attccttgaa ctagttgaaa aaactgacaa cattgaaaaa atagccttgt
     2401 ttagattatt agcatttact ggaatacgaa aaggggagct tctggcacta acttgggatg
     2461 atttgaatgg taatactcta tcaattaata aagctgtcac acgtactcaa gttggactag
     2521 aaatagatgt tacgaagaca aaatcgagcg atagattaat cagcttagat gatgaaactt
     2581 tggaaatttt acaagaactt catgaaactt ttcctacttc tactcttatg ttccaatctg
     2641 aatcaggtgg aattatgacg ccaagtttac cacgaaaatg gctattgcaa attatcaaag
     2701 ggacagactt accacaaatc acaattcatg gtttcaggca cactcatgca agcttacttt
     2761 tcgaatcagg tctatccttg aaacaggtgc aacataggtt agggcatgga gatttacaga
     2821 caactatgaa cgtatatact cacatcacgc aatcggcaat tgatgacatt ggaactaaat
     2881 tcaatcaatt tgttactaac aagcaactag attgacaact aattctcaac aaacgttaat
     2941 ttaacaacat ccaagtaact cccaccagct ccatcaatgc ttaccgtaag taatcataac
     3001 ttactaaaac cttgttacat caaggttttt tctttttgtc ttgttcatga gtttccgtta
     3061 tccctatagc cataccatca cgcttaccga tactccatca ataccactca aaaccttgtc
     3121 atatcagatc tttttgacca tttttttcat gaatatctaa aaaaaagaat caaaatagta
     3181 ctaaattccc catagcgcat gcgctatggg gaatcatagc tatatcttgt ttataattta
     3241 tgatataata cagcaaaaat agtttaggaa ataacatatg acaaaaaaac acttactaac
     3301 acttcttctc atctcttttt ttactagctt tttggtagct tgttcaacaa cgaaagataa
     3361 agagcctcaa ccgtctgatt cagaaatcat tactccccga ctacaccaag ccgctcatca
     3421 agataaacgc gctaactttg aaaaaattaa acttgcgact gttgattcct catttacagg
     3481 agggacaagc cttgaagaac ttatttcact ctttggagag cctagccaac atgatccaaa
     3541 aacagcaggc gaagtaacaa tcgacgctta tacttggcag tttgatcaag ttactctcac
     3601 tgttaatctt tatcaaaata gtagtattgt taaaaccatc tctaatttta cctttgcaag
     3661 agagttaggc ttatcgcaaa aggaatacca acaattacaa aaaggaatgt cttatgaaga
     3721 cgttaaaaag atcttaacag aacctgataa ttatagccaa gcgtcatcta gtgatcatca
     3781 aactttgcaa gcgatttggg ttagtggctt aaagacagat acaagcggag ctaatatttc
     3841 tctcgttttt gaaaataatc agttaacaga aatgtctcag gtaggacttg aagaataaaa
     3901 aatgagtaat atattttgct aaaaagattg atttcgatgt acaccgaaat caatcttttt
     3961 atatcatttt aataaaaaac tttagtgtaa tttcttataa ttgccttcat agatcgataa
     4021 acagacttgt tttacgctta atgtaataat taatctaagt ctgaagaaaa atcataagac
     4081 agcagaaact actgtcttat gatttagttt aagcatgtta cggtaccgct accccacatt
     4141 gcaattatta ttttttatcg tgaatgccaa atatcttcgt tatactgctc aatggtacgg
     4201 tcagatgaga agaatccagc ttttgcgatg ttatggacca cttttgtcat ccataaatct
     4261 tggtcttcat agtctgctaa cattttttct ttcacttcaa tgtactcttc aaggtcaatc
     4321 aaagtcatga accagtcttt tgaaatcaat tctttataaa gacgatcaag acgttcttcg
     4381 ttgccaaatg ctagcaattc tggactgata ataaagttca ctgctgcttt aatagcagga
     4441 tggttatcat agtaatcttt tgctacataa gaagcagtcg cataaaggtt gatgatggtg
     4501 tcagaatctt taccaaaggt gtagatattc tccatgcctg caagctcagc gatttctacg
     4561 ttagcaccgt ccattgtacc aagtgttaaa gcaccgttaa gcatgaattt catattacca
     4621 gttccagaag cttctttgga tgctagtgaa atttgctcag aaatatcagt tgctggaatc
     4681 aagtgctctg ctactgtcac gttgtaattt tcaactagat gcacattaag gtatgggctt
     4741 acttcagggt cattgttaat caattcagac aagcaaagga tcaagtgaat gatgtcttga
     4801 gcaatgatgt aagcaggcgc tgctttacct ccaaagataa cagtgatttt acgttttgga
     4861 aggttgcctt ttttaatttc caaatatttg tgaatcacgt aaagagcatt catctgttga
     4921 cgtttgtact cgtggaaacg tttgatttgg gtatcaataa tagaatgttc atcaagctca
     4981 atgcctttat tgtctttaag gtaacgttta agagctaatt tgttgttgaa tttgatttca
     5041 gccaatttag catgaacagc tttgtcatct gcaaaggcca tcaatttttc taattttgtt
     5101 gcgtcagtca agtactcatc gccaataagt tctttaatgt aatcagccaa gtcttggtta
     5161 gcaaattcta gccaacgacg gaaagtaatc ccgttggttt tgttgttgaa tttttctggg
     5221 taaaggtcat agaaagcttt taattcgctg tttttcaaga tttctgtgtg gagtgctgct
     5281 accccattga cacttgttgc aaaatgaata tccatatggg ccatgtgcac acgacctgat
     5341 tcgtcaataa tttgaacagc tggatcagac acttctgaac gaacaagagc atccaatttt
     5401 tcaatgatgg ttaccaagtg tggcactact tcgtttaagt aagcagttgg ccatttttca
     5461 agggcttctg caagaatagt gtggttagtg taaccaacca tatttttcac aacagctacc
     5521 gcttcatcaa agtcaaagcc atgtttttca gtcaagagac gaattaattc tgggatgacc
     5581 attgatggat gcgtgtcatt gatttgcacg taagcgtagt ctgcaaggtc atgaaggttt
     5641 gaatcacgtt cgatagcttc atcaatgatt aattgcgctg catttgacac cataaagtac
     5701 tgttggtaaa tacggagcaa ttccccattt ttgtcagaat cgtctgggta gaggaacaag
     5761 gtcaagtttt tagcaatttg cgttttatca aatgaaatac cgtctttgat taacccgtaa
     5821 tcaacgccct cgatatcaaa caagttaagg tagtttttag tgtcgcgttt gtaacccaaa
     5881 acatcaatac gatcaagacg agatttcaag gtgaagttct taaaaggcac atcgtaagaa
     5941 atgtctgttg gaaccaacca tgagtcatct tcaatccaga agtttggctc agcttcttgc
     6001 tcattgtgtt tgaagacttg cttaaacaac ccacaatgat agtttaaacc aaccccttca
     6061 ccattaatcc caagagatga aatagagtca atgaaacatg aagcaaggcg tcctaaacca
     6121 ccattaccta gtgatggttc taattcaaca tcttcgactt ctgcgataga tttgccagca
     6181 gctgccaatt cttctttgat atctttataa attcctaggt taatcaggtt gtttgatagt
     6241 aatttaccaa tcaaaaattc cgctgagata tagtaaactt tgcgtttggc agtattttta
     6301 gctttgtggc tagcttcttc tttgacaaag tttaataatg atagataaat ctcttcattg
     6361 ctagcctgcg taagtgattt tcctagttta gtttcaacat attctgtaaa gcgtgtcatg
     6421 tcttcctctt ttcaataatg taacatttaa atattatctt gcgcgaccat aaagatctgt
     6481 taaataaata aggtaatctt tgtgatcttg gttcaattca ccgtcaagca tacgccattg
     6541 ccaattacct ccaattgtat ttggcatatt catacgactc ttaccatctt tatctaataa
     6601 atcttggatg caaagaatgg ctgtatcaca aacagaagca aagattgttc ttagcatggc
     6661 ttttgtaata ctttcatctg catgtttgtg aagatagtta tttacaaagt gtacttgttc
     6721 ttcactaaga ttgtcatacc atccgttaac cacctcgtta tcatgagtcc ctgtgtaagc
     6781 gacacaatta cggtcatagt aatgtggtaa atctatactt tgactcgtta tatcaaataa
     6841 accaaattct aatatcttca tgccaggaaa gcctgttgat gctaatagct gctctgcttt
     6901 ttcatcaata taaccaaggt tttctgcgat gatagggagc tctcctaagg cctcacgaac
     6961 cgcagaaaat aatgctatac ctggggctga ggcccaatgg ccatttctag cagttttatc
     7021 accagcagga atttcccaaa aatctgagaa gcctttaaaa tgatcgattc ttagctgatc
     7081 atatagtttg aaactttctt gaatacgata aatccaccat gcaaaattag acttttcatg
     7141 agcagaccaa ttgtaggttg gatttcccca cagctgacca tcttcactaa agccatctgc
     7201 tggtacacct gcaataaaca atggcttttt atcactatct actttaaata gctcaggcat
     7261 cgtccaaact tctacactgt ccgcagaaac ataaataggc atatcaccaa taatttctat
     7321 ccctttatgg ttagcgtaag ttttcaaggc tgaccattgt tggtaaaaga agtattgaca
     7381 gactttatga taggtaatct tttttgcaag caactcacgg taattattaa gtgagtcttc
     7441 ttggcgttta atgacagttt cgtcgtccca atcttgtaag gctttattgt taaaatattc
     7501 ttttaaagcc ataaattcag caaaatcagt taaccagcta gaagctgttt caaaagcttc
     7561 taatttacac acattttctt gttcagcaac aaaagctctc actgcttttt ctaaaagtgg
     7621 acgcctaact tgaaaaagct gagcatagtc tactgcttca ggatttgtgc cgaatgtaat
     7681 atcacacaaa tctgctgctt ctaaaagttc atcatctact agcaattcaa aatcaatgaa
     7741 atgtgtgttc ccagcaatag ctgaaaatga ctgataagga gaatctccaa aactcgtcgt
     7801 tgttaaaggc agaatttgcc aataggtttg tttcgtctct gctagaaaat caacaaattc
     7861 aaaagctgat tttccaaaag tgcctatccc aaatttccca ggcagggaac taatatgcat
     7921 taagataccg cttgcacgtt tgttcatgat ttttctcctt gtgaaatcta ttcatgatga
     7981 gattataacg caagcgcttg cgtaagtcaa ccagtttcct aaaaaaagta acattcctta
     8041 aaaatgctac ttttttttgc tcttaatgac taatatcacg gacgctttct ctttgtttta
     8101 aactaaaagg aacaaaaata gtctgactaa gattctgttc attggaattg ataatatcaa
     8161 gtaattgctt aaaagacatt tttccaagat tttcaacatt tatatcaaat gtcgttaaat
     8221 aagggtgaat taatttagcg taattagaat tattaaaagt gataattgac atatcatctg
     8281 gcacttttat atcataaaaa gataataact gtaccatacg aatagccaga acatcaccaa
     8341 caacaaccaa ggcagttgct ttaaaggaag atatagtttc catcaatatt tctacgctaa
     8401 caggatcctt acgatcaaat aacagcattg gcttcgtttt taaagatcgc ttaaaacaac
     8461 ccttcaaata gccaagataa cgctcagaag ttacttctga tagtaaatca tctgttataa
     8521 ataatatgtt gtgatggcct ttttgataaa ggtgttctac tgctgtttta gccattagct
     8581 gattatcatt atcaatataa gtggttttat tagtgtcacc ttgtggagca cctacaatga
     8641 caaatggtaa gttatttgtc atcaaatatt ttttgacagg atcatcttga tcagaataaa
     8701 gaataataaa accatcaact cgtttttgaa gatgcatcag tttcacttgc tctatcaggt
     8761 catcaagaga tatacctgta gcaatcgaca cagtaaaatg agattcttta gcttcgttag
     8821 taatagtcga caaaatttcc ataaagaaag gttcacttaa tctatcgcta gttgtaatag
     8881 gaggaaaaac aagtcctata ttgtgtgtca aaccactcgc tagaatctgt gctgcgacat
     8941 ttggaacata tcccaaatct gccatcgctt ttctaacctt ctcttttgtt ttcatagaaa
     9001 tagatcgatt atcttttaat accctactca ccgtcgaagg gttaacacct gccttttgag
     9061 cgacatcttt tattgttacc atattaacct cgttactata tttaccaaag ataaacctta
     9121 tcatgggttt gtcatgtatt tcgtttccat tatacaatta tctttcaaaa aatcaacttc
     9181 aatcaagatt cccttgtcat tttaactcaa attctctaaa ctatttttaa aaaaaacgac
     9241 ctttttttaa aaaaaggctt gactttttct gcaagcggtt gcataatatt aagtgtaaga
     9301 aatatacctt aggaggaaat agctatgaaa tcatggcaaa aagttatcgt cggcggagca
     9361 agtttgacac ttgcaagtac cttgttagtg ggatgtggat caggttcaaa agataaaaag
     9421 gaagctggcg ctgactcaaa gactattaaa ctttgggtac cgactggctc taaaaaatca
     9481 tatgcagata ccattgcaaa atttgaaaaa gattctggtt acaccgttaa agtggttgaa
     9541 tcagaagatc caaaagcaca agaaaaaatc aaaaaagatg cctcaactgc tgccgatgtc
     9601 ttttcacttc ctcatgatca acttggtcaa cttgtagaat ctggtactat tcaagaagtt
     9661 ccagaaaagt acaataaaga aattgctgct acttctactg atcaggcgct cgtcggtgca
     9721 cagtacaaag ggaaaacata tgctttccca tttggtattg aatcacaaat tcttttctac
     9781 aataaatcaa aattagctgc tgaagacgtt acttcatatg atacaattac tacaaaagca
     9841 acttttggtg gtacctttaa acaagctaac acttacgcta ctggtccatt attcatgtca
     9901 gttggtaaca ctttatttgg ggaaaacggt gaagatgtaa aaggtactaa ctggggcaat
     9961 gaaaaaggcg ctgctgttct taaatggatc gcagaccaag cttcaaataa aggttttgtt
    10021 agcttagatg ctaacaacgt tatgtctaaa tttggtgacg gttcagtagc ttcttttgaa
    10081 tcaggaccgt gggactatga agctgctcaa aaagctatcg gtaaagaaaa ccttggtgtt
    10141 gctatttatc caaaagtaac tattggaggc gaaacggttc aacaaaaagc attcttgggt
    10201 gtaaaacttt acgcagtcaa ccaagcacca gctaaaggtg atacaaaacg tatcgcagct
    10261 agctacaaat tggcatccta cttgactaat gctgaaagcc aagaaaacca attcaagact
    10321 cgtaacattg tcccagccaa caaagaagtt caatcttcag aagctgttca atcaaacgaa
    10381 cttgctaaaa ccgttatcac tatgggttct tcttcagact acactgtcgt aatgccaaaa
    10441 cttagccaaa tgggcacatt ctggactgaa agtgctgcta ttcttagtga tgccttcaac
    10501 ggtaaaatca aagaaagcga ctaccttact aagttgcaac aattcgacaa agatatcgct
    10561 gcaacaaaat aatatgatct catgtcatca ctgctatact aaaacaagca caaggtaagt
    10621 acttctaaaa agttctttcc acttacctta tgaagagtgg aactaggctc catcacattt
    10681 tattcaagct tagtctcact cttacttgtt tttgttttac tagtagctta gtgctactta
    10741 aatttttaac tctttaaaag tttacgtaac acttagctat ttcatcctaa caagagattg
    10801 aatctgaact accactctag tatcctaaaa taaaggagaa tctatatgac tcagtcaaac
    10861 ttgacaccaa atatatctgt aatagaagct ttaaaaagag gcagttggga tattaaactt
    10921 tcgagtatta tcatgggatt tgccaacttt gctaacaaac agtttatcaa aggaatctta
    10981 tttttaataa gtgaacttat ctttctagta gcttttgtct cccaaatcat ccctgctatc
    11041 cgtggccttg tcactcttgg tactcaaact cagggaatga ctacaaaaac tattgatggg
    11101 attaacatcc aagttgctgt tgatggcgat aactctatgc taatgcttat ttttggttta
    11161 gcatcactca ttttctgcct agtctttgct tacatttact ggtgtaatct caaaagtgct
    11221 cgtaaccttt atcttttcaa acaaaaaggt cagaagatac caaacttcaa agaagatctt
    11281 gccacactta caaatggtcg ctttcatatg actttaatgg ctatcccact gattggtgtg
    11341 cttttattca ccattcttcc tttgatttac atgatctgtt tggcctttac caattttgat
    11401 cataatcact tgcctccaaa atctttattt gattgggtgg gacttgctaa ctttggaaat
    11461 gttttaagcg gccgtatggc aggaaccttt tttcctatct tctcatggac tttgatttgg
    11521 gctgtttttg ccacagtaac taatttcttc tttggtatta ttcttgcttt gttaatcaat
    11581 gccaaaggat taaagtggaa aaaaatgtgg cgaaccatct ttgttatcac cattgcagtt
    11641 ccacaattca tctcattatt gattatgcgg aacttactca atgacgaagg cccactaaat
    11701 gctcttctca ataaaatcgg cttgattaat ggctcactgc catttttatc tgatcctctt
    11761 tgggcaaaat tctcaatcat ttttgtcaac atgtggatcg gtattccatt taccatgttg
    11821 attgcgactg gtattatcat gaaccttcca agtgaacaaa ttgaggctgc tgaaattgat
    11881 ggcgctagca aattccaagt cttcaagtct atcacattcc ctcaaattct cttgatcatg
    11941 acaccaaact tgattcaaca atttatcgga aatatcaata actttaacgt catttacctc
    12001 cttactggtg gtggtccaac aaattcagaa tactatcagg caggaacaac agacttgctg
    12061 gtcacttggc tctataaatt aaccgtcaca gctgctgact acaatttagc ttctgttatc
    12121 ggtatcttaa tctttacagt ttcagctatc tttagcttac ttgcttatac aaggacagca
    12181 tcctacaagg aaggagcggc taaataatga aaaacaaacg tcgatttcaa cttggacttg
    12241 tttatgctac tttaatcatc ctctcaatca tttggctctt cccaatcgct tgggttattc
    12301 ttactagctt ccgtagcgaa ggaactgctt acgtcaatta ttttattcct aagactttta
    12361 cattaaatca ctacattaat ctttttacta atgaaacctt tccttttgga aaatggttta
    12421 tgaatactct tattgtagcc acttttacat gtattatttc aaccttcata actgttgcca
    12481 tagcctactc tcttagccga attaagttta agtttcgcaa tggcttttta aaactagccc
    12541 ttattttaaa tatgttccct ggtttcatga gcatgattgc catctactat atcttaaagg
    12601 ccttaggttt gacgcaaacc ctaacagcac ttgtccttgt ttattcctca ggtgcagccc
    12661 ttggttttta cattgcaaaa ggattttttg ataccattcc ttattcactt gatgaatcag
    12721 ctatgattga tggcgctact cgtatggata ttttctttaa aataaccctt cctttagcaa
    12781 aaccaatcat tgtctatact gcccttcttg cttttatggg gccttggatt gactttatct
    12841 ttgcacaagt tatcttaggt gatgctacaa gtaaatatac cgttgctatt ggactatttt
    12901 caatgcttca gccagatacc attaacaact ggtttatggc cttcactgct ggttctgtct
    12961 taattgccgt cccaatcact ctcctcttca tgtttatgca aaaatactat gttgaaggca
    13021 tcacaggtgg ttctgttaaa taagttacaa cataccaaac cttctaaggg caagcccttt
    13081 aggaggtttt tgataaataa ggccgtagat aatcatatta gtcctcacat ttatcttcag
    13141 atcagccaaa tgtattaatg attccttgac ttttaccatg aattcggata taacaaaatg
    13201 atgacatcta aaattaccat taaagatatt gcacgagaag ccggggtttc tgtggcgacc
    13261 gtatcttacg tgttaaacca gcgcaatgat caaaaaatca gcgaagaaac ccgcaataaa
    13321 gtgctacata ttagtaacct tcttaactat acacctaatc aggcagccag ggcattagtc
    13381 acacaacaat caaacagtgt tgtcctgtat tacaaatatg cagatagcat tttagctagg
    13441 gctgaacaac tgcataccat tagctttcta tcccgcctat tgcatgagca ggactatcag
    13501 ctggtttgcc taaatgaaga tagcattgaa aaatttgact gggcagacct tattctgacc
    13561 ttggacgttg ataatgatac cttttacaaa attggaaagc ttaatttcaa acccttaatt
    13621 gccattgata gctttgttaa tgatcccctc ttctttcaaa ttaatacaga ttatgctgct
    13681 ctcaaagatc aggctaatca gttttttaag gatgaacctt ataccctgct ttccttgcct
    13741 atcactaatc gtgagcgata tgagcatgtt tctgccttct ttccaagttt gcacattgta
    13801 aacgacctaa gagagctaac ctactttgaa aaggaaaatc ttttactcat tgatgagagt
    13861 ttggatcaat tctttgtgaa ctcttcgcaa aaactctact gcccacgttt ttccccaaaa
    13921 aaagggcaag ttatcttaga ggccatcgaa tgggccaaaa aacgccagcc tgataaaaaa
    13981 cataaccttc tggtgtaacg cctgagaatt aacctatctt gactaattcc ttgtaactca
    14041 aaaccttgcc tctttagata aagaagcaag gttttttgat gtctaatcta ataacagggc
    14101 ctgacttgtc tcatcaatct ctaaactgtg ttttgtagaa cacccaggtc agcattaata
    14161 aggtaccaaa tacttggcaa ttcataatca gtactggatc ctgaataaag aaactaagag
    14221 caatcgccag tagactcggc caagccaaac aattaaccat caatccaagt ccttcagaga
    14281 agtttcgaat cataaatagc cgtgatcgtt tagtcagagt caaaaagaaa gcgcctagac
    14341 caatcacaat aagggtaccc acacacacca tgagaacaaa cgtcagcaaa agaaaaccaa
    14401 gtacactggc tttattactg tcataccatt gctgattgac aaagtccttc actgctttaa
    14461 ctgttgtcag gtcagcgagt gactgctgct ggcctctaac gtgagcacgg agttccttgc
    14521 catcaggggt aacaaaacgc cattcttttt ttgtcacaat aatttgtctg gttgattctg
    14581 atgccaattg ctctaaatcg acctttgtcg gtaaaacagc caaaaccaat tcaccatctc
    14641 gtcgaatcag agattgaccc tgaaacgtat ctttctcaat ctttccttgg gtcaatgctt
    14701 gataggtttt gtctgtgata ggcgacaaac tcttagttac aatccgttcc aagggatacg
    14761 ttgtcatgtt agcatagtgt aacgtaactg gaatcattat taaggcgttc aaaaaaacaa
    14821 taataagaag attttgccac caagtaaact gagctcggct ggcaaacatt gccctagcag
    14881 aaaggcaatg tgaaatgtaa gaaataggaa attgtttttt atctggcatt aaacattact
    14941 ccttgtcagg ttaccctttg gtaccaccac ttgttaaacc ggaaacgaaa tttttctgta
    15001 ggaagaaaaa gagaactgaa ataggcactg caatcagaat agctcccgca gcaaataagg
    15061 ttaccttggg atttctagca tcattcgtaa taaacgattg aagaccaact gctaccgtat
    15121 aattttcttg cgcccttaaa aggaatttag ccaacatgaa gtctccgaaa ggacccataa
    15181 aagcccataa ggattgtact gcaatcattg gtcgcacaag aggaaggaca atttggtaga
    15241 aggtcctaaa gtgtccagaa ccatctaact tagcagattc gtccaagtca taaggtaccg
    15301 tgtcaaaata acccttcatc aaccaggcat tcataggaat accaccaccg acgtaaatca
    15361 aaatcaagaa ccagtattgg tttaaggcat taaagagcca cgccataaca aagtaagccg
    15421 ttaaagccgc catggtagga accatctgta cgactaggaa aaagattaaa ctttttttgc
    15481 gtccaaagaa attgtaacgg ctatacgcat aacctgtcaa agtgatgact gttacttgta
    15541 tgagcatggt gaagaatgcc acgatcaagg tattccaata ccatcttaag tataaggtat
    15601 cttgaaagag tgttttaaag ttagacaagg tccatggccc atcaaaatga aaactaaagg
    15661 ctgtggtatt tcctggtcta aaagctgaac tgaccgtcac tagtattggg aataaaatca
    15721 cgatcactaa ggagattaga tagagataag tcaataattg ggtgaagaaa cgtttgcgtt
    15781 tcatggatat tgaaacatag gtctttctca tgatctctcc tccatatcaa aagctttaaa
    15841 tttcttaaag gtaatcaacg ataccgaaat cactattaca gagatgatta aggtcactgc
    15901 cgacgccatc gaaaactgag gcgaggtttg tgtggtcaac ttgtaaatcc aagaaatcag
    15961 aatatcagtt gtcccagctc cgccccccac agtaccaggg cccccattat taaacagata
    16021 aataatagag aaattattga agttaaaggt gtactgagag ataaaggttg gtgctgcaac
    16081 cgcaaaaatc attggcatgg tgatatggcg gaatttctgt aagactgtcg caccatcaac
    16141 ggttgctgct tcgtataaat cagctggaat tgcctgtaaa atacctgata ccaaaatata
    16201 gatataggga aatcctagcc aaccttgcac cataataaca gccacttttg tccagaaggg
    16261 gtctgtcttc caggacacaa ttccgaagtc aacgaaagga aggaatttct cgatgaaagg
    16321 aagaacctga acattcatgg ccccaatgga atcattaaag aaattaccaa aactcataat
    16381 agagataaat gctggaacag cccatggtaa caagaatatc acaccaaaga gacgttttcc
    16441 tctgataaag gattgattag caataacagc cgttgcaatt ccaataacaa tttgaagact
    16501 tgtcgctgct aatgtccaga tcagcgtcca tgacaaaaca gatgtaaatg ctgttttgaa
    16561 ggtgcttaat tctaagatat taagaaaatt cttcaaccct acccaatcca ataaacgata
    16621 cggaggaata tgcctaaaat cgtaattggt aaaagcaatc agcaaggtca ctaaaactgg
    16681 aaaaataata gcgaaagcca ttgctaaata agccggaatg atgagcaagt aaggaaatcc
    16741 tttttcataa atcgcttcaa gggtctcttt agccgtcacc ggaaccttct tgccttcatt
    16801 catttgatgt gcaactaatt tagcatctct catagcaacc aaatgaaaaa taccaaataa
    16861 gactagagta attaattgca tggccccctt aattaacata aataaggagt gatcttgcat
    16921 tggaacactt ccaagactgt aaaaacctgt taaagcagga attcctagaa ctacaatttc
    16981 tagtagttct aggaagaaaa caactaataa gactccccct ttaacgattt gtttattgta
    17041 tagttgtccc aaacctggga taacagatag ccacatggct ttattaggct tctgttgtct
    17101 ttggttatct accatttttt attcctcttc tcataaatga tttaaggtta tactccttat
    17161 catactaact tccttttaag ctgactaatt tattttttta tagtaatggt ttgtgcttca
    17221 tgacctgtct ttatactata agtctcagga cttgtccata aaacattccc aatactatct
    17281 tttttaacaa gtttgactgc tatttcttta ttgattggta gatgagtatc aaagaaccag
    17341 tttgggtact tggcaatggt ctgagtgtta ttaaatagag gaccaacagc attcttagcg
    17401 tcatttgccc ccatctcaaa aacatcaccc atgagatata gttgttcccc tggtactgtc
    17461 ttaaaatcat tgatgagtaa acgaacagga atttgtttat cagtcaatac ttcaaaggct
    17521 tggtaactat tgctggtttg cttatcggca gttgtcactg aaatgttata ataatttgct
    17581 ggaaccgtcg gtacttttaa ggtgataagg gtatctgacc aagaaaggat ctcagcagag
    17641 atttctccaa aagtcacttg acctttagaa ttaccaaaac cttgacctga aatagtaatc
    17701 ttatttccag caatacccac tgaagcatcg acatctccaa gttgtggtgt cttgtcctct
    17761 ccttcataag tccatacagc gacttgcccc gctccaagtt caaagctact aatagtgcca
    17821 tctgctccaa ctattaattc ttgaccgcca agaagacctt ctaatttgtc cttgtagcta
    17881 ttttggggca aggctgtttt agcattagta attgtataac cattcgtttg atctctatta
    17941 atagccacta gtgcgacatg attaccaaat ttacgctcaa ataccaaaac atgatcacta
    18001 atccaacgtt gttcagttgt tccataagct aaagcttgat tttgttttct taaaggagct
    18061 agcttactaa tcactttata ggcttgtgac tctttattaa aacttggcat atcaccacga
    18121 ttattaggat ctttatcacc tgttgcatac tgctctgtac cataataaat attaggcaca
    18181 cctctagatg ttaaaagcaa agcataggct tgattaacag cagtttgatt attagccact
    18241 tttgttgcga agcgttccat atcatgatta tcaataaagg tcacctggtc tgtcacttca
    18301 ttagtcacct gatctctatt ttcaagaacc ttgtaaaaat ctcgcatggt aaacgttgaa
    18361 aaacctgtat acaactgtct aatagcattg gcaaatctaa aatctaaaag ccccatccca
    18421 ctattgttag caaatgtcgt catatcataa tcatcgtcgg tatgtcccga gaaccattcc
    18481 ccgaaaacaa agacattatg tttttcatag atatgactca accaattttt ttgccaacct
    18541 tgtgacatat gtttaacagc gtcaactcgg ataccatcaa cacccaggtc taaccattta
    18601 tcaatagctt ctttcatgta ctggtcaact ttcggattaa tgttatttaa atcagctagt
    18661 ccgtacattg aatgataaat agaattttca taagtactaa aatcggtcca agattcatga
    18721 ttaaaaatct tgtctttatc atctgaaaat ttaccaacta atttaccgtt tttatataaa
    18781 gcgccatctt ctttgaaagt tgtgccttct ttttcggctg tagacgtatg attaggagca
    18841 aaatcaataa ctaccttaat atggtgttga tgagctactt tgactagttg ttgaaagtct
    18901 gcttcagtgc caaaatgctg gtttgtttta aagaagtcct tagcccaata cccatgatat
    18961 gcagcacttc cattagaagg atcaatactg tcgatatttt caacaggaga agaaatccaa
    19021 atggcagaaa tccccatatc tgtcaggtaa ccatccttaa tcttggcgat gattccttgc
    19081 caatcacctc catggtattt tttaaggtca tttttatcaa aaacatcagt cttaccatta
    19141 ttagaggtat taccatcgtt aaaacgatct gttacaatct gataaatcgt atctgttgaa
    19201 aaatctgctt tgttggtgac agaagcatta tcggcagcag aaacagttag tggaaatgaa
    19261 attaagccaa gtaaaacagc acttttcgtt aataacttat aagttttgat atgtaattct
    19321 ctcatcgctt tttccttttc aaataacctt ttagttacta aacacaatat atccatcctg
    19381 gagtaattgt tttttgtttt tagttacccc attgcttgtc aaaatctgtc ctccttcctt
    19441 aatagaataa gcactctcac cattgttaag aacaagtgaa atgctttgct cacctaagct
    19501 gcgtttcaga atgaggcagt cttcgtcata atcaatgcta atagctcctt cttgaagagc
    19561 tggctgttgg cgaagagcaa taatcgcttt tactttgcta aagaaatcct tgtcccgctc
    19621 agcatcatcc caaggaaaac cgcgacgcga atcagggtcg taaccccctt ccattgccac
    19681 ttctgtccca taatacaagc aaggaatgcc cataaagata aagagcaatg ctaaagcagc
    19741 taacaattta tctttggaac ccttaacttg agtgaagaaa cgatgcgtat catgagaatc
    19801 caaaagattc aagttcatgc gattgacttg ccaagtgttt cgcatcaaaa tgttgcttaa
    19861 tttctcagcc aattgttttg atgtcatggt ttcaaaagca aagtaatcca aacaggcttt
    19921 ggtgaaagca taattcatta tcccatcata ctgatcccct gccaaataag gataggcatc
    19981 atgccagttc tccccaatta aaatggcatc tgctttttcc gctttaaccg cctgacggaa
    20041 acgtcgccaa aaatcatgag atacttcatc agaaacatct aggcgccaac catcgataca
    20101 aaattcttta atccagtatc gcccaatctc aatcagatag tcttgcacgt ctctatttga
    20161 ggtattccat ttgggcatat agttacatcc agcaaaggtt tcatagttta ctaggtccat
    20221 ggatgggtgt tcatcatgag tcataaacca atcaaaaaac ttagactctt taccgtatct
    20281 caagacatcc tgaaattcca cggcatcact gctggcatgg ttaaagacag cgtctagaat
    20341 aatcttgatt cccatttggt gagctaaatc aatcaattct tgcaaatcat atttagttcc
    20401 aaattgtgga tcaatagcgt agtaatcact aatatcatat ttgtgattac taatggattg
    20461 aaaaattggc gttaaataga tgacagtaat ccctaaatct ttgaggtaat ctaatttttc
    20521 tgtaattccc tttaaatctc caccagcaaa acttttagga gtcggttttt ctaaccaacc
    20581 catgttgaca taactgtcac ctttttccca atccccacgg ttaaagcgat caacaaagat
    20641 ttgataaaaa accgcgtctt ttgtccaagg aatgacttga tgaacatcaa cagcattgat
    20701 ataaggcatt tggaagaaat tataaaaccc atttgaaaaa tcgtaactag tagttaaccc
    20761 atcttcacta aaataatagg tttgaccttc ttcttcaatt ttaaaaatgt aggccaacct
    20821 cacatcgtct aatgttaaag tagtttcata ataagcatgc gtatggtctg tataggcaac
    20881 tgacatttcc aattcttctt ggaattcatg ataaccatat ttaggcccgt ggaccaaatt
    20941 aacagtaata cctctatctt ctttggccac gcgtaatcgg atgacaagtt ccttttgaga
    21001 tatggcaaag caatacctcg aatcaggaat atggagcatt ccggcaacat tcatttctac
    21061 ctccattaat aaagtattga cgattacttc tttttcttta aaacgaaaaa atagcagagc
    21121 gactcatact tctatatttt tagtatctgt ttcatcttca tcaaactaac agaaatagaa
    21181 gctgggcgta cttctttatc ccagcctccc ttctttgcct tattcagcgt atttttgttc
    21241 aatagcttcc ttaatagttt ttgctgcttc ttttgcagct ttagatgctt cttccttacc
    21301 agaagccacg ttaaagaaca tatttgcacc tggttcccaa acttcagcca tttctggaat
    21361 atttggcatt ggttgtgcgc tctcaaactg actaatcaca gctttcgtta actcattacc
    21421 ctctttagaa gcatagttac gtgctgttaa gttagctgga atttcttgtg ttttatcata
    21481 gaaacgtttt tggttttcag cattggtcac ataatcaagg aatttttgag cagtcgtttt
    21541 tcctttagaa tagtttgaaa taacccaagc tttaccacct gcgaacggtt ggtatttttt
    21601 accatttgtc aaagtaggaa tttccattac cccaaagtta acaccagcat ctttaaagga
    21661 gctagctgcc catggaccat caataatgac accagctttt ttagaaataa attgttcagt
    21721 gataaaatca ccagcttttt tagtgtcttg cattccttga ggccaagtgc cataccactg
    21781 tttcgcgtag tttaaccctt caacagttcc gtcgttacct aggcctaaat cacttggttt
    21841 ggttccttta tcaccaaaga tataaccgcc ataaccggca attaaaccat aaccataata
    21901 gaagtctgtc catttcgcca agaaacctac agattttcct ggttcagagg caaaagcaaa
    21961 cttagaatct ttttgtaaga cttctaattc agtaaagctt ttaggtgctt gaggcactaa
    22021 atccttatta taataagtta ccaaagtttc aattacgtct ggtgcaccat aagttttacc
    22081 atcaatggtt actaatttct taaccgtatc atcaaactct ttgctgtttc ctaaagtaac
    22141 ctcagagatt tgaccttcag ttcctaagcc acctacacgg tcaaaaggtg ctaaaaagac
    22201 atctggtgaa gctcctgttg gaccatccgt tgatagctta tcaagagtat ccatcatacc
    22261 ttcttttttg actttaacgg tgactttatg ctctttttca aactcaccct taatactctt
    22321 aatgtaatca acatatccct catcaacaga gactacaata gtctttccgt ctgtttcctt
    22381 aacgccttta ccaccaccac ttacgcaagc agttaggggt agcactgaag ctaaggataa
    22441 agttccaagc acagatgctt ttttccaatt ccatgacata acatgttcct cccgaaatgg
    22501 ttttttctta aacacaaatc aaatcatcta tctactctca tcatattagc aaataaaaga
    22561 taacataagg catttaaaat taataacagt aatagtttcg aaacttaaac gtttaagtta
    22621 agtttatcgt aatcgctttc atttgtcaat aactttttta cttttctttt aagagcatat
    22681 cagtagtttt tctgctaatt gaaaacaagg catttactgt cacacaagtc tgtcctttct
    22741 tttttctaca actttatttc gtcagcgtaa ataaaacaaa agctctataa tctcttgaat
    22801 gggtaaaccc actgtagaga ttatagagct ttttgaatat caaaaaagtc ccataaaatt
    22861 tataatgaaa agcaaccaaa ctctcattag aaagactctt atggaacata tcaatcatac
    22921 cttacaacac atcggaatta aagacaaaaa tatcactcta aacaatgttt tgaaggatga
    22981 atctcctact gagctcgtta ctacttacca gaaaggtaga taggaaatcc tgatgaagag
    23041 tgtgtccaag ggattatcaa ttaggtctta gattacaaaa tagtaattca ggtaggctct
    23101 actgttttca acactagttc tgcaatttgt tttcgagctt gcttagcttc tcttattgga
    23161 aaaataacat acgcatgaat cattttttct gcaataatca gctgattagc aattcgttgt
    23221 cttgttaatt gatcatgtaa agacataatg tctgggtaaa aaatttcttt tgtcccaaca
    23281 aaggtcgtta tttcaggcaa atcctcacaa tcaccataca aaggactgac ataaggaagt
    23341 tgcatattac cttgaccacc tgcccatagt tcacctatat cacgaagacg acgagcatct
    23401 aggtaagctt cttctgcttc aaaatccttg taggcttgat ttttaaaact aacatctaac
    23461 caaggagata taagaattaa ttgctttggc tgtagtgctg ttttagtatc tcgtatatac
    23521 ttagcaaacg ccaaagccat ccccccacca gaagaatcac caatgacact aacttgactc
    23581 ggtccattag acaagcaaaa ttgctggtaa gcttcaacta atttaggata gacatcttga
    23641 taagtagcat acggtacttt aggaaagtta ggaaaaacaa ccttggcatt agtcagctgt
    23701 ataagatgct taaccgtctt aaaatgaagt ttttcgggtc gtcgtaaata gacactgcca
    23761 taaagataat aaataacagg ctgatgactt tgcttttgat cattaataat aaaaacttgt
    23821 atcccgttca catcgtattc ttgagttgaa aaacctacta tctcttcagg attatctaga
    23881 tgataaggga tattacgatt acgctgcgtc tcaaccccct tataattatc aactttttta
    23941 gataacttat actttctata agcaaacatt ttctcaacca accaacttga aaaggagcgc
    24001 ttttgaccat attcaactat caaaatacct agtatcactc caaaaaaaat caccacagca
    24061 ataatgacca cttattatcc tcgttttcta atattatttt actattgcaa gtctttccta
    24121 tttgcccaaa ttttactata aaaataaggg ttcattttat agttgggcac tggctgcttc
    24181 gtttctagaa atggttgcac tttcttatca aaagctaacc agccattcca accgagatgg
    24241 atggtatctt gcataaagta ggactcacca ccatcttttg agaagtcagc aatgcgatga
    24301 aatccttgtg actttaactg gaattttatt ttacgaactg ccgcttgata cttatcttga
    24361 tttaagccgg tataatccgc ccaagcttta ttaacaggag ttataacaaa gagtacatct
    24421 gtttttcgtt tagcaaattc tgataataaa agctgaaaat cattgtattc tggtgacgcc
    24481 aggtaactat aattaacttg gaaattctta taaagattgt atttaggtgc tattcgttta
    24541 cgataaaatg tatttttaat cccaaaacgg ttgttggttg ttgctaattg gcctctctta
    24601 gttgctaacg cattcaattg tttatacgaa aatactttag gtaatccctt aacgcgaggc
    24661 aaaattcttt tttcatagtt agtagatttg cctaaaaaac taaaaaggga ctcttctctc
    24721 aatgctactt gatgttgaca tttcaaaata gctctgtcta accgactaag agacttaccc
    24781 ttacttactt ttttcaataa gtttgattta gacacaccag ggttaagctc aagcaaacgc
    24841 tttgctgcaa actgtgattc tttatcagtt ctagctttta gtaaaaattc aatcacttga
    24901 gtgttagaca agtacatctg aaccgcacta ggattaatcc cttgagcagt aaaccattga
    24961 ggagatacta caaagatggc ttttttcttt tgcatttcat tggtaatttg ttgcatacca
    25021 taataatgcg acaaagatgc tgatcctctc ttaccaatta aaaatggtct atagctccgc
    25081 ttgtagcgct ctgcaagcac cgaagggtgc atactatcca ttcgactcca ttcgctagaa
    25141 ccaaaaaaag gcacaaaacg acaagtctca tctgataaag cttgtctttt aatcaaacca
    25201 tttttaaaag aactatctgt gatcgcaacg gcatttgctt tttcctgagc tatggaatga
    25261 tcaagttgtg taggaaaact aaaaatagta atcactacta aaacaaaggc aataagaaga
    25321 ggacctagaa ttaaccagag tctcttaagc atgttgcaat tcctctacac cttgaacaat
    25381 cttagttact gtgttccaat catcacgacc aaattctgaa ataggtactt taatattgaa
    25441 cgttgactct aactcaacaa tcaattcgac tgtcccaaga ctatccaaca cacctgcatc
    25501 aaacaagtct tcgtccatca tctctgaaac atcttccata aacaaacggt caaacaattc
    25561 aattacagtt tcttcaatag acatttttat acttcctttt attaatgtag tggtctgtta
    25621 aaccaaaggt catttaaaaa accagagaat aacagaagtg aaaacatgac aacgtggaaa
    25681 gttaccacga tacataagac atggaatgcc ctgctttgaa agaggggtga taagcctttt
    25741 ttcttacggt gacggttgat ttcttttttc ttacgaatcc aagcatcatt aataataagt
    25801 cctataccat ggaaaagccc ataagcgata taataccagg ttaagccatg ccaaaatccc
    25861 atgactagca tattaaccag ataggcaaca cctgaagtga catttcggtt tttaaaggtt
    25921 ttatgcttaa tcaatagatg aaccaatcgc ataaacacat aatctctaaa ccagaaggac
    25981 aaactcatgt gccatctatt ccaaaaatct ttcaagcttg cagataagaa aggcatgtta
    26041 aagttttctg gtgttcgaat acccaatagg taggaaatac caatcgcaaa catcgaataa
    26101 ccagcaaagt caaaaaagag attcaagcca tacacgtaca taaccagaat agtttcctta
    26161 ttaaagtagc caccaaccat caaagcctta ttttcaagga gaggaagtaa gatgccaccc
    26221 aaacaatagg aaatgatatg cttgtatagg aaacctaaca tgagatacat gactgcctta
    26281 ttgagcattg caaaataatc atcacgttca ggaagtttat gataatcttc ctgaaaacgt
    26341 ctgaagcgat caatggggcc acttgagaaa gtggggaaga aaatcatgaa gcgaataaaa
    26401 tccggtaaac gaacctcttg gagagtcccg tcacgcatct caataatcat tccaatactt
    26461 ttaaaggtca aatatgaaat ccctagaaaa ctaaagagtg tttgagaaga aggacctgtt
    26521 aggggagcaa ctttgaccca gataaggggg aataaggcca tcgcaatagc taagtaaaac
    26581 actcctgcac tattagcttt ctcacggtat ttctggtaag caaaaacact gatgatttgc
    26641 cacaaaagat aaaagagaaa agcaactaat tgttgataat gatctcctcc aaacataaag
    26701 agaataaata ccaaacttac caaggtttca taagtgctta agcgcttttg tttaaaaatc
    26761 ccaatgatga ctggtaagaa agccaaaata agatagacaa agtaaatggg gttaccgtaa
    26821 ggttccatgt agggaatgtg gctaaaaaac atcatcatcg gttattgacc tcattaatca
    26881 aagttttaat atctatctta ccatttggag ttaatggtag actgtctcga taaagaaact
    26941 tagaaggcat catataactc atcatatgat ccttaacaga ggctttgata gctttggtta
    27001 actccaattc cctatcaaaa cgctctttaa ccccatcttt gacaacgata taggccaaga
    27061 gattttgaac cttatgttct ttattgtacc ttggaacagc cacagccgat gctaccattg
    27121 gtgattgatt caactgttgg gaaacatctt ctagttcaat acgataacca gcatatttaa
    27181 tctgaaaatc caaacgccca ccatacagca aaatattatc ttctgtcagt gagccaatgt
    27241 cccctgtatg ataagcaggc tgtcctttaa aagtaaagaa agcttctgcg gttttctcag
    27301 gattgttgag gtaacctttt gacacagcag gccctgtaac aataatttca ccctgctccc
    27361 ctgaagctaa ctccttacca tcttcatcaa taatataggt cggagaatct ggtttggggt
    27421 agccaatcgg caagcgggta taattatcca ccatttctct ggtaatttca atagcggata
    27481 aggctacagt cgcttctgtt ggtccatagg cattgatgat cttggcactc gggaaacgtt
    27541 caaagagttt tcgagccgta gaaacggtta attcttcgcc atcaaaataa aaatgcgtta
    27601 aagctggcat cttagcctgg caaaaatcat cgctaagcat ggccatatca gcaaatgaag
    27661 gagtcgatgt ccaaatgcca actggaagtt gcgcaatcgt tgtaaataac tgtttaaagt
    27721 ctgccaccaa ttcttttgga agtgcaaata aggttccacc taaagccaag gtaggtgccc
    27781 agtacatgac agaaaggtca aaggaatagg gtggctgcgc cagcatttgt ggctgtttag
    27841 gtacatcaaa tgctgcatct tcgatcatcc agttggtaaa gctcaaaaga ttgtcatgtg
    27901 aaatttgcac cccttttggt tggcccgttg ttccagaggt gaaaataatg taataattat
    27961 catctccttt aacagaatgt gttcgctcat agggcatttc tgctaatttt gctgactcaa
    28021 tctctgatag tgagacaagg gaaatccctt caatagtaag agggaattcc tcaatagcaa
    28081 tgattaaact gggctttgca atctcaataa tcgctaaaat acgttctggt gctgaatgca
    28141 catctactgg gatataggca tgaccagatt tggttaaagc tacaaaagta gctaacatat
    28201 cataagtttg cgccccaaaa accaaaactg gagattttgc cagtaaagct aagctatcta
    28261 taaatgcagc aatgctatca gaatctcttt tgagttgtcc gtaagtgcgg tgttccccta
    28321 aacaatcata aactgggaaa tcagcctgtg tctgagcaaa ctgctcaata ctgtcaatca
    28381 tatccttaat catcagtcaa tctcctaaaa ttcattataa ataaagttac tttgaccatg
    28441 tcctagataa ccaaagaaat agaccagcaa cattaaaatc agataaaata aaattgtctt
    28501 gccaataaaa acagcaattc ctctcattct tgatttgttt tttatc
//
LOCUS       DATWEK010000021        26615 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.021, whole genome shotgun sequence.
ACCESSION   DATWEK010000021 DATWEK010000000
VERSION     DATWEK010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26615
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.021"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            551..769
                     /locus_tag="VCR92_001124"
     CDS             551..769
                     /locus_tag="VCR92_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4268197.1"
                     /translation="MYPRIRNLREDNDFTQKFVANLLSFSHANYAKIERGEVALMADV
                     LVQFSKLYNVSIDYLLGQTDYPYRFHNK"
     gene            complement(840..983)
                     /locus_tag="VCR92_001125"
     CDS             complement(840..983)
                     /locus_tag="VCR92_001125"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268198.1"
                     /translation="MGISPTGLLRWQPERSEVSLSLFVVMADREPLYFIANNYRSYHG
                     VSH"
     gene            1070..1290
                     /locus_tag="VCR92_001126"
                     /pseudo
     CDS             1070..1290
                     /locus_tag="VCR92_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903600.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
     gene            1992..2375
                     /locus_tag="VCR92_001127"
     CDS             1992..2375
                     /locus_tag="VCR92_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEP4268199.1"
                     /translation="MKVHTTLEKDENGNWYRKDQTKTPAGERLIELDDVTIVVLENWR
                     RNQVVNTDTDFIISRFGEPFCKSTICRVIKHKAQEVGVPVITGKGLRHSHASYLINVL
                     KKDILYVAKCMGHADKSTTLNTYSH"
     gene            2638..3873
                     /locus_tag="VCR92_001128"
     CDS             2638..3873
                     /locus_tag="VCR92_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEP4268200.1"
                     /translation="MIKRWVILFFMVLTCSGFGKTVLAADFQVGAEHAIVVEADSGRV
                     LYEKDAKTPDAIASLTKLVTAYLVLDKVKSGQLQLSDQVNLSDYAFELTKDRSLSNVP
                     FDKKTYSVQDLLTATLVASSNSAAIALAEKVAGSELHFVNQMREQLSHWGITSGKILN
                     ASGLPNEVLKDNRYPGSALEEENTLSAQDVAVVTMHLLEDFPEILEITKQTEVNFAGN
                     SIKSFNQLLPGMAKGRAGVDGLKTGTTDLAGHCLVVTSIENGMRVITVILNADGSDKN
                     QNTRFEQANRLLDYVDRTYCRRKILKKGSLVLERSLPIQDGQVKELPVSVAEDVTIIL
                     QQGEQVPKPKQFMISETSLLAPITKGEVVAYLTSPRITDQSVRYLKEPKRIPLKASQS
                     LKKASDLQLWWRDFLEKRR"
     gene            complement(3989..4951)
                     /locus_tag="VCR92_001129"
     CDS             complement(3989..4951)
                     /locus_tag="VCR92_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEP4268201.1"
                     /translation="MNNRHKRRQKRKAFTLINLILLFACILGLTLIFYLYQGSNKFGL
                     SDVSQFVPKISLFHHKKTAKKETTKLKKTHFDSSKSQKKAHSKLTWTKQETPVKIPIL
                     MYHAIHVMFPEETANANLIVNPDLFDQQLQKMKDEGYYFLSPEEVYRALSNNELPAKK
                     VVWLTFDDSMIDFYNVAYPILKKYDAKATNNVITGLTEIGSAANLTLKQMKEMKQFGM
                     SFQDHTVNHPDLEQASPDVQTTEMKDSKDYLDKQLNQNTIAIAYPSGRYNDTTLQIAA
                     RLNYKLGVTTNEGIASAANGLLSLNRIRILPNMSPENLLQTMEP"
     gene            5283..6560
                     /locus_tag="VCR92_001130"
     CDS             5283..6560
                     /locus_tag="VCR92_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEP4268202.1"
                     /translation="MTYEETLEWIHDHLVFGIKPGLKRMLWVLGQLGNPQKNVKGVHI
                     VGTNGKGSTVNHLQHIFTTAGYEVGTFTSPYIMDFKERISINGRMISEKDLVIAANRI
                     RPLTERLVQETDFGEVTEFEVITLIMFLYFGDMHPVDIAIIEAGLGGLYDSTNVFQAM
                     VVVCPSIGLDHQAILGETYADIAAQKAGVLEGGETLVFAVENPSAREVFLTKAEQVGA
                     SIWEWQEQFQMAENASGYRFTSPLGVISDIHIAMPGHHQVSNAALAIMTCLTLKDRYP
                     RLTSDHIREGLANSLWLGRTELLAPNLMIDGAHNNESVAALVAVLKNNYNDKKLHILF
                     GAIDTKPIADMLVALEQIGDLQVTGFHYPNAYPLEKYPERFGRVADFKDFLALRKHAK
                     ADDFFVITGSLYFISEIRQYWKKHIEKNVLLTH"
     gene            6595..7179
                     /gene="folE"
                     /locus_tag="VCR92_001131"
     CDS             6595..7179
                     /gene="folE"
                     /locus_tag="VCR92_001131"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEP4268203.1"
                     /translation="MKRERLMSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKM
                     YAEMFLGLGKDPKEEFTAVFKEQHEDVVIVKDISFYSICEHHLVPFYGKAHIAYLPSD
                     GRVTGLSKLARAVEVASKRPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCMTMRG
                     IKKPGSKTITTTARGLYKESRAERQEVISLMTKD"
     gene            7188..7988
                     /gene="folP"
                     /locus_tag="VCR92_001132"
     CDS             7188..7988
                     /gene="folP"
                     /locus_tag="VCR92_001132"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEP4268204.1"
                     /translation="MKIGKFVIEGNAAIMGILNVTPDSFSDGGSYTTVQKALDHVEQM
                     IADGAKIIDVGGESTRPGCQFVSATDEIDRVVPVIKAIKENYDILISIDTYKTETARA
                     ALEAGADILNDVWAGLYDGQMFALAAEYDAPIILMHNQDEEVYQEVTQDVCDFLGNRA
                     QAALDAGVPKNNIWVDPGFGFAKSVQQNTELLKGLDRVCHLGYPVLFGISRKRVVDAL
                     LGGNTKAKERDGATAALSAYALGKGCQIVRVHDVKANQDIVAVLSQLM"
     gene            7995..8354
                     /gene="folB"
                     /locus_tag="VCR92_001133"
     CDS             7995..8354
                     /gene="folB"
                     /locus_tag="VCR92_001133"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEP4268205.1"
                     /translation="MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLS
                     DQLTDTVHYGMVFDSVRQLVEGEKFILIERLAGAICEQLFNEFPPIEAIKVAIKKENP
                     PIAGHYKAVGIELERQR"
     gene            8351..8851
                     /gene="folK"
                     /locus_tag="VCR92_001134"
     CDS             8351..8851
                     /gene="folK"
                     /locus_tag="VCR92_001134"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEP4268206.1"
                     /translation="MTIVYLSLGTNMGDRAAYLQKALEALADLPQTRLLAQSSIYETT
                     AWGKTGQADFLNMACQLDTQLTAADFLKETQAIEQSLGRVRHEKWGSRTIDIDILLFG
                     EEFYDTKELKVPHPYMTERAFVLIPLLELQPDLKLPPNHKFLRDYLAALDQSDITLFS
                     AQQTEF"
     gene            9001..9888
                     /gene="murB"
                     /locus_tag="VCR92_001135"
     CDS             9001..9888
                     /gene="murB"
                     /locus_tag="VCR92_001135"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEP4268207.1"
                     /translation="MITELHGIDIRENEPLKHYTYTKVGGPADFLAFPRNHYELSRIV
                     AYANKENMPWLVLGNASNLIVRDGGIRGFVIMFDKLNAVHLNGYTLEAEAGANLIETT
                     KIAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEISHIFLSAKVLTSSGEIKTISAR
                     DMAFGYRHSAIQETGDIVISAKFALKPGNYDTISQEMNRLNHLRQLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMEANLKGHRIGGVEVSEKHAGFMINVVDGTAKDYEDLIAYVIETV
                     ENHSGVRLEPEVRIIGENL"
     gene            9934..11088
                     /locus_tag="VCR92_001136"
     CDS             9934..11088
                     /locus_tag="VCR92_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4268208.1"
                     /translation="MTKPIITFNNVSKTFEDSGTQVLKNINFDLEEGKFYTLLGASGS
                     GKSTILNIMAGLLDASSGDIYLDGERINDLPINKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKKEIAKRVKETLKMVQLEGYENRSIQKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWVFVMNEGEIVQ
                     SGTPVDIYDEPINHFVANFIGESNIINGTMIEDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIEGEVIG
                     LDFTPEDLHIMRLNETEEEFDARIEEYVEMDEPEDGLINAIEEERNEENL"
     gene            11072..11866
                     /locus_tag="VCR92_001137"
     CDS             11072..11866
                     /locus_tag="VCR92_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4268209.1"
                     /translation="MKKTSSLFSIPYFLWILFFVVAPVTLLFYKSFFDIEGRVTLANY
                     ETFFSSWTYLRMSVNSILYAGIITLVTLLISYPTALFLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGIGPQQILFTDFSFIFVASYIELPFMMLPIFNA
                     LDDIDHNVINASRDLGASEFQAFSKVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTQNWGMGSTIGVVLILTMVAIMWLTKEKSK"
     gene            11863..12639
                     /locus_tag="VCR92_001138"
     CDS             11863..12639
                     /locus_tag="VCR92_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4268210.1"
                     /translation="MKKFANLYLASVFVLLYIPIFYLIFYSFNKGGDMNGFTGFTLEH
                     YQTMFEDSRLMTILLQTFVLAFSSALLATIIGTFGAIFIHHVRGKYQNAMLSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGMSSVLLSHIAFSIPIVVLMVLPRLKEMNQDMVNAA
                     YDLGANYFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARQGISLDINALSTIVFFFSILLVIGYYYMSQDKEEKHA"
     gene            12632..13705
                     /locus_tag="VCR92_001139"
     CDS             12632..13705
                     /locus_tag="VCR92_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEP4268211.1"
                     /translation="MRKLYSFLAGVLGVIVILTSLSFILQKKSGSGSQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEN
                     LLNKLDKSKLVGMDNIGKEFLGKSFDPQNDYSLPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYKNSIMLIDGAREMLGVGLTTFGYSVNSKNLEQLQAAERKLQQLTPNVKAIVA
                     DEMKGYMIQGDAAIGITFSGEASEMLDSNEHLHYIVPSEGSNLWFDNLVLPKTMKHEK
                     EAYAFLNFINRPENAAQNAAYIGYATPNKKAKALLPDEIKNDPAFYPTDDIIKKLEVY
                     DNLGSRWLGIYNDLYLQFKMYRK"
     gene            complement(13760..14425)
                     /locus_tag="VCR92_001140"
     CDS             complement(13760..14425)
                     /locus_tag="VCR92_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEP4268212.1"
                     /translation="MNVLIIEDDPMVDFIHRNYLEKLNLFDRIISSDSMKAVQSILTD
                     YAIDLILLDIHITDGNGIQFLEKWRAQHIPCEVIIISAANDGNIIRDGFHLGIIDYLI
                     KPFTFERFQESIQQFVTHREHLANQQLEQAQIDQLKCLTSKKDTKNKQLLEKGLSEST
                     FQWIIENIKAFDQPFTIQELASACHLSHVSVRKYIAYLEENKQLNSQQIFTKVGRPYR
                     VYW"
     gene            complement(14406..15947)
                     /locus_tag="VCR92_001141"
     CDS             complement(14406..15947)
                     /locus_tag="VCR92_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP4268213.1"
                     /translation="MKKPLRLWASLSLILVSMIVVTTSLFYGIMLHDTHQSIKNQETH
                     LLTSTGKMLASHQAIKELLLNNQPNAKTTAYTNSIASIYNLDYVVVMNMKGIRLTRPN
                     PKNIGKPFQGGDEEAVLAGKKVISTAKGTLGKSLRYLVPVFDGDKQIGAIAVGIKLTT
                     LNDVALTSKRNYTLSLFLCLLISLLVTSFISFRLKRQLHQLEPSEIYQLFEERNAMLD
                     QIEAAVFVVDKTGILQLCNQAGQELIARKCQLGKPTGNSFNHLFPDFPKLSLQEGHEQ
                     LFRYGEEDYLLAISPICVKNDHRGHIIFMREAVKAIDTLDQLAYTTAYASALQAQTHK
                     FMNQLHVIYGLVDIAYYDQLKIYLDSILEPENEILTSLSVLVKEPLLASFLIGEQEKY
                     QELNVHLKIDVLSEIPHSVTKNQLNNGLMIYRFIHTNLLTTLRPKSLVLSIQHDQNHL
                     ISHYTLTDNWIDLERVQPIFDLPYFQQLLTDTNSQFHQHQTVTELQFSVTTPYVGWQH
                     ERFNH"
     gene            16108..17439
                     /locus_tag="VCR92_001142"
     CDS             16108..17439
                     /locus_tag="VCR92_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HEP4268214.1"
                     /translation="METISKKMPQKDLSEHSKAWQNRRIGSVPLPVYLVLATLILITG
                     WLQQLPVNMLGGFAVILTLGWLLGTIGATIPGLKHFGGPAILSLLVPSILVFFNLLNP
                     NVLEATNVLMKQANFLYFYIACLVCGSILGMNRKILIQGLFRMIIPMLLGMVCAMGVG
                     TLVGVILGLDWQHTLFYVVTPVLAGGIGEGILPLSLGYSAITGVGSEQLVAQLIPATI
                     IGNFFAILCTALLNRFGEKHPSYSGQGQLVKIGHSEDMSDALKDNSGALDVKLMGAGV
                     LTACSLFIAGGLLQHLTGFPGPVLMIILAAFLKYLNVIPQETQNGAKQLYKFISSNFT
                     FPLMAGLGLLYIPLKEVVATLSWQYFIVVISVVLTVVSVGFFVSRFLNMNPVEAAIIS
                     ACQSGMGGTGDVAILSTADRMNLMPFAQVATRLGGAITVITMTAILRIIFS"
     gene            17471..18637
                     /locus_tag="VCR92_001143"
     CDS             17471..18637
                     /locus_tag="VCR92_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HEP4268215.1"
                     /translation="MKNQLGQLALEQAKTFGGKLEVQPKVDITNKHDLSIAYTPGVAG
                     VSSAIAKDKTLAYDLTTKKNTVAVISDGTAVLGLGDIGPEAAMPVMEGKAALFKAFAG
                     VDAIPIVLDTKDTEEIISIVKALAPTFGGINLEDISAPRCFEIEQRLIKECHIPVFHD
                     DQHGTAIVVLAAIFNSLKLLQKSLDEVSIVVNGGGSAGLSITRKLLAAGATKVTVVDK
                     FGIINEQEADQLAPHHLDIAKVTNREFKSGTLEDALEGADIFIGVSAPGVLKAEWISK
                     MAARPVIFAMANPIPEIYPDEALEAGAYIVGTGRSDFPNQINNVLAFPGIFRGALDAR
                     AKTITVEMQIAAAKGIASLVPGDALSTTNIIPDAFKEGVAEIVAKSVRSVVLKS"
     gene            complement(18719..19657)
                     /locus_tag="VCR92_001144"
     CDS             complement(18719..19657)
                     /locus_tag="VCR92_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn-dependent alcohol dehydrogenase"
                     /protein_id="HEP4268216.1"
                     /translation="MKAATYLSTGNLQLIDKPKPVIIKPTYRPVGKNHSICGTDLHIL
                     GGDVPACKEGTILGPEGIGIVKEIGDAVTNFKIGDKVIISCVTSCHTCYYCKRGLSSH
                     CEDGGWILGHLINGTQAEYVHIPHADGSLYHAPDTIDDEALVMLSDILPTSYEIGVLP
                     SHVKPGDNVCIVGAGPVGLAALLTVQLFSPANIIMVDLSQNRLEAAKTFGATHTICSG
                     SSEEVKAIIDDITNGRGVDISMECVGYPATFDICQKIISVGGHIANVGVHGKPVDFNL
                     DELWIKNITLNTGLVNANTTEMLLNVLKVIIDNDIS"
     gene            19893..20624
                     /gene="aphA"
                     /locus_tag="VCR92_001145"
     CDS             19893..20624
                     /gene="aphA"
                     /locus_tag="VCR92_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HEP4268217.1"
                     /translation="MKKEFTSILFTVSFCGIIALPVEASGPKVPYTQEGITAISNQAT
                     VKLISIADIASSLEGQKPITVSFDIDDTLLFTSQYFQYGKEYITPGSFDFLHKQKFWD
                     LVAKRGDQDSIPKEYAKQLIAMHQKRGDKIVFITGRTRGSMYKKGEIDKTAKSLAKDF
                     KLDKPIAINYTGDKAVKPYQYDKTYYIKKNGSQIHYGDSDEDINAAKEAGARPIRILR
                     APNSTNLPLPKAGGYGEEVLENSAY"
     gene            20802..22334
                     /locus_tag="VCR92_001146"
     CDS             20802..22334
                     /locus_tag="VCR92_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEP4268218.1"
                     /translation="MENHKNEFTFSNKSIIAYVWRGVMVGIIAGVIVSLFRLLIEVTA
                     DWVIEWYRYAHINSLLLLPILSVSLLAVLFVGFLVKSDSDIKGSGIPHVEGELKGLMS
                     PDWWSVLWKKFLGGIMAISMGFMLGREGPSIQLGAMSAKGLAKFLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLIWITALVASLVANFISLNIFGLKPVLA
                     MSEAMPFLGLNQYWLLLLLGLFLGCLGYLYEIVILNFNKLYVILGNWLHLPAYFYGII
                     MVFLILPIGYYLPQLLGGGHGLILSLSNQQLPLMTIFFYFIIRFIVSMFSYGSGLPGG
                     IFLPILTLGALAGLLFGQIASQLGLLNQSFLSLFLILGMAGYFAAISKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVSYLVMDLLNGQPIYEAMLDKMAMKHPTNLVEPTLIELTVG
                     DKIAGKYVKELKLPENVLITTQIHHQKSQVVSGNTRLLSGATIFLVVNEADTGFVREV
                     LM"
     gene            22497..23111
                     /locus_tag="VCR92_001147"
     CDS             22497..23111
                     /locus_tag="VCR92_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEP4268219.1"
                     /translation="MLEIVSEELRHYQEQKLIEYRNKNQLAPKGGIVFAGDSLIEFFP
                     LKKAFGSCLPIINRGIAGIDSQWLLRHFSVQITDLEPKHIFLLIGCNDIGLGYDKCHI
                     VKTIVELISQIRSHCVYSQIYLLSLLPVSNNPRYQKTVKIRTNAMIDAINKDLAMIPT
                     IEFINLNTCLKDEKGGLSDENTLDGLHLNFPAYAKLAEIIQAYI"
     gene            23270..24418
                     /locus_tag="VCR92_001148"
     CDS             23270..24418
                     /locus_tag="VCR92_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEP4268220.1"
                     /translation="MIIKGVTMKFEKKQVFYLVLTFILCYGILANWRNGTAIVTTIYK
                     TSLPFFYGAAGAYIVNIVMSAYEKVYVYIFKDWSHVLKVKRGICLLLAYLTFFILITW
                     IISIVIPDLITSISTLTKFDTITIQEVVNNLEHNKLLARTIQYIGGDGKLTETIANYS
                     QQLLKQFLTVLTNILTSVTVIASAIINLFISFVFSLYVLASKEDLCRQGNTLVDTYTG
                     KYAKRIHYLLELLHQRFHGFFVSQTLEAMILGSLTASGMFILRLPFAGTIGVLVAFTA
                     LIPVIGASIGAAIGFILIMTQSMSQAIIFIIFLIILQQIEGNFIYPKVVGGSIGLPAM
                     WVLMAITIGASLKGIVGMIIAVPLAATLYQVIKDNIQKRQAIQKKQVS"
     gene            24467..25147
                     /gene="radC"
                     /locus_tag="VCR92_001149"
     CDS             24467..25147
                     /gene="radC"
                     /locus_tag="VCR92_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEP4268221.1"
                     /translation="MYSIKCDDNKAMPRERLMRLGAESLSNQELLAILLRTGNKEKHV
                     LELSSYLLSHLDSLADFKKMSLQELQHLAGIGKVKAIEIKAMIELVSRILATDKTLTD
                     SVLTSVQVAEKMMAALGDKKQEHLVVLYLDNQNRIFEEKTIFIGTVRRSLAEPREILY
                     YACKNMATSLIVIHNHPSGNIEPSSNDYCFTEKIKRSCEDLGIICLDHIIVSYKDYYS
                     FREKSTLF"
     gene            complement(25149..25844)
                     /locus_tag="VCR92_001150"
     CDS             complement(25149..25844)
                     /locus_tag="VCR92_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEP4268222.1"
                     /translation="MTKPIIGITANQRLNMALDNLPWSYAPTGFVQAVTQSGGLPLLL
                     PIGDEAAAKTYVSMVDKIILIGGQNVDPKYYQEEKAAFDDDFSPERDTFELAIIKEAI
                     TLKKPILGICRGTQLMNVALGGNLNQHIDSHWQEAPSDFLSHEMIIEPDSILYPIYGH
                     KTLINSFHRQSLKTIAKDLKVIARDPRDGTIEAVISTNDAIPFLGVQWHPELLQGVRD
                     EDLQLFRLFVNDF"
     gene            complement(25854..26498)
                     /locus_tag="VCR92_001151"
     CDS             complement(25854..26498)
                     /locus_tag="VCR92_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEP4268223.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFHADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTNVILVGCGNIGRALLHY
                     RFHDRNKMQIAMGFDTDDNALVGTKTADNIPVHGISSVKERIANTDIETAILTVPSIH
                     AQEVTDQLIEAGIKGILSFAPVHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
BASE COUNT         8121 a         4437 c         5505 g         8552 t
ORIGIN      
        1 actattggta taaatgtatc tctcagacta cttattttga atagtttaat ttatatcatt
       61 tttgcctatg taacctatct gatcaatcat attattagct atatatttag tacaggtgtg
      121 gcattaggta tttcaatggt aggtgttatt gttgcagctt tttgtgaaac gagccttggt
      181 gataaggtat ggtttcttat tccatgggca tggcttttaa gaatatcaga tactctatat
      241 aaccaacaga aaatggcaat tgttccactt attgttatat tttttgtttc atgcacagta
      301 gctttacttc atatacgaat atttaaaagt tggaatcaag actgtttgac aagtagttaa
      361 atacatctat tttgtttacc taacaataaa tatgattttt aagttataaa tactatctaa
      421 cttgtttaac taaaaaatga ctataaaatt tcaatggttt actagcttat atttaataga
      481 cttgtccaaa taggacaatt aaacattttt taatcaaatc tcctttatac tgatattcgg
      541 agaatgttag atgtatccgc gtattaggaa tttgagagaa gataacgatt tcactcaaaa
      601 gtttgttgca aatttacttt ccttctctca tgcaaattat gcaaaaattg agagaggaga
      661 ggttgcctta atggcagatg ttcttgtgca gttttctaaa ctctataacg tcagtattga
      721 ttatttatta gggcaaacag attatccgta tcgttttcat aataaataaa agtctcgcct
      781 tgatttgttc attgacaact gaataaaccg aggtgggact ttcttgtttg tcgagcaatt
      841 tagtgagata cgccgtgata ggagcgataa ttattagcta taaaatagag tggttctcta
      901 tctgccatga ccacaaatag ggacaatgat acttctgaac gttcaggctg ccagcgtaaa
      961 aggccagtgg gtgagattcc catgagtgat ttaaccagtc atacccacgg aggttgtaat
     1021 ttttttgaaa ggagtggagg tgtgaaaata gtaacatata aaaagcttga tgaatattgg
     1081 ttttctcgaa catactgcaa gaaatattat tagagaagca aaaagaatag ctataaaaaa
     1141 gttgaagaag ctcgcgaact tgaacaaaat gcggtacaat taagtaaatc gccctttgac
     1201 aatagaagac ttggtattgc tcctaaagat attgtagaag agttagtagg tgttctactc
     1261 tctgaagaaa gtttagaaag tgagaattaa agatgactat aaaaaatcaa aaaaagtaca
     1321 aaggtgttta ttgtgataag aatgggaaga tattttatca agctgatctt ggtgtagatc
     1381 cagtaacagg taaacgagtt caaaagaaag ccagaaagaa ttagtatgga aagccatttg
     1441 gtacaatgaa agaagcgtat gatgaactgg ttcggattag gtatgagttc agtaataatc
     1501 ttagtattga aaatgacaat atatcgtttg aaaactatat gaatactatt tacctaagag
     1561 catataagca aaaggttcag gctgtaactt atgaaatagc cttaccacat cataagttat
     1621 ttattcagta ttttggttct aaacttttaa agggaataac agcttgagat tgtgaatctt
     1681 ttagtttaca tattattgaa aattatgcaa agaatttatg gtcgcgattc aaagcttgca
     1741 tggggtatgc tgaaaggtta gactatattt caaaagtgcc atgtaaggct ttggataatc
     1801 ctaaagggaa acatcccgac actccatttt ggacttatat tgagtttcag aattttataa
     1861 aatcgtttga tttgcaagat tatgaagagc tacaaagatt tacaactatt tggctatatt
     1921 atatgacagg tgttcgtgta agtgaaggtt tatcattatg atgggaaaat atcgatttcg
     1981 aacaaaaatt cttgaaagtt catacaacct tggaaaagga tgaaaatgga aattggtatc
     2041 gtaaagacca aacaaaaacg ccagcaggag aacgtcttat tgagttagat gatgtgacaa
     2101 tagtagtatt ggaaaattgg agaagaaatc aagtagtcaa tactgacaca gatttcatta
     2161 tttcacggtt tggtgaacca ttttgtaaat caacgatttg tcgagttatt aagcacaaag
     2221 ctcaagaagt aggagtacca gtgataacgg gaaaaggctt gcgacatagt catgcttcct
     2281 atcttattaa tgttttgaaa aaagacattc tgtacgttgc aaagtgtatg ggacatgctg
     2341 ataagtctac aactttgaat acatatagtc actgatttaa cgcattagat aaaacagtat
     2401 ctgaagaaat aacccaaaat gtaataagtt caggattaga ttccatttta taccaaaatt
     2461 cctgccaaac aactaattga tataacgaag cttattatat cgcccatata acaggatgtg
     2521 ttattgttac agggtacttg ctttatgagc ttgtttaagc tactaaaggt gggtgccact
     2581 atacttcctt ccaaatttct gagaattttt gctataatag taactatgaa agatataatg
     2641 ataaaaaggt gggttatcct tttttttatg gtattaactt gttcagggtt tggtaaaaca
     2701 gttctcgcag ctgattttca agtgggagca gaacatgcga ttgtcgtaga ggcagactct
     2761 gggagagttc tgtatgagaa agacgctaag acgccagatg ctattgcctc tttgaccaaa
     2821 ttggtgacgg cttatctggt tttagataag gttaaatcag gccagctgca attatcagat
     2881 caagttaatc tctcagatta tgcctttgag ttaacaaaag ataggtcttt aagtaatgta
     2941 ccttttgaca aaaaaactta ttcagttcaa gacctgttga cagctacttt ggtagcaagc
     3001 tcaaatagcg ctgctattgc gttagccgaa aaagtggcgg gctcagagct tcattttgta
     3061 aatcaaatga gagaacagct atctcattgg gggattactt ctggtaaaat cctcaacgcc
     3121 tcaggtctgc caaatgaggt gttaaaggac aatcgttatc ctggttctgc gttggaagaa
     3181 gaaaatacct tgagtgctca agatgttgca gttgtgacga tgcatttgtt agaagatttt
     3241 cctgagattt tagagatcac caaacaaaca gaagttaatt ttgctggcaa ttctattaaa
     3301 agttttaatc aactcttacc aggtatggct aagggtagag caggagtgga tggtttaaag
     3361 actgggacaa cagacttggc aggtcattgt cttgtggtaa cttctattga aaatggtatg
     3421 cgagtgatta ccgttattct aaatgccgat ggatctgata aaaaccaaaa cacgcgattt
     3481 gagcaagcaa atcgtttgtt ggactatgtg gatagaactt attgtcgtcg taagattctt
     3541 aaaaaaggaa gtcttgtctt ggagcgatcg ctccctattc aagatggcca agtaaaagaa
     3601 ctaccggtat ctgttgccga agatgtaacc atcattttgc aacagggtga acaagtcccc
     3661 aaacctaaac aatttatgat atcagagact tctttactag caccgattac taaaggtgaa
     3721 gtggttgctt atttgacgtc tccacgaata acagatcagt cagtgaggta tttaaaggaa
     3781 cctaagcgta ttcctcttaa agctagccaa tctcttaaaa aagcctctga cttacagctg
     3841 tggtggcgag attttcttga aaaaagacgt taaagataag aataaaataa ttttaaaaca
     3901 atcaaaaaag acagttatga aagaattttt tcataactgt ctttttagtt tacagtgagt
     3961 atgatttgga atgataaaaa aattgatgtt atggttccat tgtttgtaaa agattttccg
     4021 gactcatgtt tgggaggata cgaatccggt taagagaaag aagtccatta gccgcgctag
     4081 ctattccttc gttagtggta acacctaatt tatagttaag tctagctgca atttgtaagg
     4141 tagtgtcatt atatctacca gatggataag caatggcaat agtgttttgg tttaattgct
     4201 tatcaagata gtcctttgaa tctttcattt cagttgtttg aacatcagga ctagcctgct
     4261 ctaaatcagg atgattcact gtatgatctt ggaaagacat accgaattgt ttcatttctt
     4321 tcatctgctt aagagtcaga ttggcagcgc ttcctatttc ggttagtcct gtaataacat
     4381 tattggtagc tttagcatca tattttttta agattgggta agcaacgttg tagaaatcaa
     4441 tcatactgtc atcaaatgtt agccatacaa cttttttagc aggcaattca ttatttgaaa
     4501 gagcgcggta gacctcttca ggactcaaaa aatagtagcc ctcgtctttc attttttgaa
     4561 gttgttgatc aaagagatct gggttgacaa tcaaattagc attggccgtc tcttcaggga
     4621 acattacatg aatagcatga tacattaaaa tggggatctt gacaggtgtt tcttgcttgg
     4681 tccaagttaa tttagaatgg gccttttttt gagattttga ggaatcgaaa tgagtcttct
     4741 taagttttgt cgtttctttt tttgccgtct ttttgtgatg aaaaagactt attttaggta
     4801 caaattgaga gacatctgac aagccgaatt tgttagaccc ttggtataaa tagaaaatga
     4861 gggtcaaacc aagaatgcag gcaaataata gtataaggtt aatgagagtg aaggcttttc
     4921 ttttttggcg ccgtttatgt ctattgttca ttacttgctc ctttttttga tataagtacc
     4981 tctattgtaa cattttttag agaaaagaag gcttgaagtc agcctttttt cttgtttttt
     5041 ggaagaacgt gtattaagga gtaaaaaaat tgttgtcaca gataacactt taggaggtag
     5101 caaagactat gtggggctgg tattcttatc acgtaaaaaa agcaatgaag ataaaagtgt
     5161 agtgtacttt agaagttatt tgagtgtttg gtgaggataa taaaaaaaag ggtactactc
     5221 taggttatct gctgtcactt ttttttatat atggtatact aaagatagat gtgaggtatg
     5281 aaatgactta tgaagagact ctagaatgga ttcatgatca cttagttttc ggcatcaagc
     5341 caggcttaaa acgtatgctt tgggttcttg gacagttagg aaatccccaa aaaaatgtca
     5401 agggagtgca tatcgttgga actaacggaa aaggttccac ggtcaatcat ttacaacaca
     5461 tctttacgac agctggttat gaagtgggga cctttacctc tccttatatt atggatttca
     5521 aagaacgtat tagcataaat ggtcgaatga tttcagaaaa agatttggtt attgctgcta
     5581 atcgtattcg tcctttgaca gagcgtctag ttcaagagac tgattttgga gaggtaactg
     5641 aatttgaagt gattactttg atcatgttcc tctattttgg agacatgcat cctgtagata
     5701 ttgctattat tgaagcaggc cttggcggtc tttatgattc gaccaatgtt tttcaagcaa
     5761 tggttgtggt ctgtccctca attggtttag atcaccaagc tattttggga gagacttacg
     5821 ctgatattgc cgcccaaaaa gctggtgttt tagaaggggg cgagaccctt gtttttgccg
     5881 ttgaaaaccc gtcagctcga gaggtttttt taacaaaagc tgagcaggtt ggtgcttcaa
     5941 tctgggaatg gcaagagcag tttcaaatgg ctgagaacgc atctggctat cgttttacta
     6001 gtcctttagg agttatttca gatattcaca tcgctatgcc aggacaccac caagtgtcta
     6061 atgcagcttt agctattatg acttgcttaa ccttgaaaga ccgctatcct aggctaactt
     6121 cagatcatat aagggaaggt ctggcaaata gtttgtggct aggccgtacc gaattattag
     6181 caccaaatct aatgattgat ggggctcata acaatgaaag cgttgctgct ttggtagccg
     6241 tcttaaaaaa taactacaat gataaaaagc ttcatatttt gtttggtgcg atcgacacca
     6301 agcctattgc ggatatgttg gttgctcttg agcaaatagg tgacttgcag gttactggct
     6361 ttcattaccc taacgcctat ccattggaaa aatacccaga acgttttggt agggttgctg
     6421 atttcaaaga tttcttggcc ctgcgtaagc atgccaaagc agatgacttt ttcgtgatta
     6481 cagggtcgct atattttatt tcagaaatta gacagtattg gaaaaaacat attgaaaaaa
     6541 acgttctttt aacccattaa aaaagagaaa atgaaaagga aaaggaaaaa actaatgaaa
     6601 agggaaagac taatgtctat taataaggaa aaagcagaag cagccattta tcagttttta
     6661 gaggctattg gtgaaaatcc aaatcgggaa ggtcttcttg acacgcctaa acgggttgct
     6721 aaaatgtatg cggagatgtt tttgggactg ggaaaagatc ctaaagagga gtttacggct
     6781 gtctttaaag aacaacatga ggatgtggtg attgtcaaag acattagttt ttattctata
     6841 tgtgaacacc acttagttcc tttttatggc aaggctcata tcgcttactt gccaagtgat
     6901 ggtcgagtaa caggtttgag taaattagcg cgagcagttg aagtagctag taaacgacct
     6961 caactccaag agcgtttgac ctctcaaata gcggatgctt tagttgaagc cctcaatcct
     7021 aaagggactt tagttatggt agaagcagag cacatgtgca tgaccatgcg aggcatcaaa
     7081 aagccaggta gtaaaaccat taccaccact gccagaggct tatataagga aagtcgtgct
     7141 gagaggcaag aagttatttc tctaatgaca aaagattagg agaacttatg aaaattggaa
     7201 agtttgtgat tgagggcaat gcggctatca tggggatttt aaatgtgact ccagattctt
     7261 tttcagatgg ggggtcttac actactgtgc aaaaagcatt agatcacgtt gagcaaatga
     7321 ttgctgatgg ggctaaaatc atcgacgttg gtggagaatc aacacgtcca ggttgccaat
     7381 ttgtaagcgc taccgatgaa attgaccggg tggttcctgt gatcaaggcc atcaaagaaa
     7441 actatgatat tctaatcagc attgatacct ataaaaccga aacagctaga gcagctttag
     7501 aggcgggtgc cgatattctc aatgatgttt gggcaggttt gtacgacggt caaatgtttg
     7561 ccttagcagc cgagtacgat gcgcctatca tcttgatgca taaccaagac gaagaagttt
     7621 atcaagaggt aacacaagac gtttgtgatt ttctaggcaa tagagcacaa gcagctcttg
     7681 atgctggcgt gccaaaaaac aatatttggg ttgatccagg atttggattt gccaaatctg
     7741 ttcaacagaa tacggagtta ttaaaaggat tggaccgcgt ctgtcatttg ggctatcctg
     7801 tcttgtttgg tatttcgaga aagcgtgtcg tagatgcctt gttaggcgga aacaccaaag
     7861 ctaaagagcg agacggagcg acagcagcct tgtctgctta tgcccttgga aaaggctgtc
     7921 agattgtacg cgtacacgat gtcaaggcta atcaagacat tgtggctgtg ttgagccagt
     7981 tgatgtgagg acttatggat aaaatcgtat tagaaggttg ccgtttttat ggctaccatg
     8041 gagcctttaa agaagaacag acccttgggc aaatttttct ggttgattta gaattgtcag
     8101 tcgatttgca agcagcttct ttgtcagacc aattaacaga tacggtccat tacgggatgg
     8161 tgtttgatag tgtccgtcag ttagtggaag gggaaaagtt tattttgatt gaacgtttag
     8221 caggtgcgat ttgtgaacag ctttttaacg aatttccgcc tattgaagcc atcaaagtgg
     8281 ccattaaaaa ggaaaaccca ccgattgcag gccactataa ggcagttggt attgaattgg
     8341 agagacagag atgaccattg tttatttaag tttaggcacc aatatggggg accgagcagc
     8401 ttacttgcaa aaagctcttg aggctttagc tgacttacct caaacacggt tgcttgctca
     8461 atcatccatt tatgaaacga ctgcttgggg caagacaggc caggctgatt ttctcaatat
     8521 ggcctgtcaa ttagatacac aattaaccgc ggctgatttc ttaaaagaaa cacaagctat
     8581 tgagcaatct cttggtcgtg tgaggcatga aaaatgggga tcaagaacta ttgacattga
     8641 tatcttgcta tttggagaag agttttatga cacaaaggaa ttgaaagtgc cacaccctta
     8701 tatgactgag cgtgcttttg ttttaatccc cttattggaa ttgcagccag atttaaaatt
     8761 gcctcctaat cataagtttt taagggatta tcttgcagct ttagatcaat cagatatcac
     8821 gctcttttca gctcaacaga cagagttcta gactctgttt tcggagtaat gcctgctata
     8881 agccaatcca taaagttttg ccaaattcat cgttattttt tctaaaattt gatataatag
     8941 tatcggcttt atgccgattt ttttacgcgt ataagaagtg ataaaagaaa gaagataact
     9001 atgataactg aacttcatgg gattgatatt cgagagaatg aacccctaaa acattacact
     9061 tacactaagg taggtggccc agcagatttc ttggcttttc ctagaaatca ctacgagcta
     9121 tcacgcatcg ttgcttatgc caacaaagaa aatatgcctt ggcttgtttt gggaaatgcc
     9181 agcaatctca ttgtgcgaga tggtggtatt cgtggctttg tcatcatgtt tgataagcta
     9241 aatgcagtgc acttaaatgg ttatacctta gaagccgaag ctggtgccaa tctgattgaa
     9301 acaacgaaga ttgccaaatt ccatagttta acagggtttg aatttgcatg tggcattcct
     9361 ggaagcattg ggggtgctgt ttttatgaat gcgggtgcct atggtgggga aatatcacat
     9421 attttcttat ccgctaaggt gcttacctca agtggagaga tcaaaaccat ttcagctagg
     9481 gatatggctt ttggttaccg tcactctgcc attcaagaaa caggtgacat tgtcatttct
     9541 gctaagtttg ctcttaaacc gggtaattat gatacgatca gccaagaaat gaatcggtta
     9601 aatcaccttc gccaactaaa acaaccttta gaatttccat cttgtggatc tgtgtttaag
     9661 cgcccgccag gacactttgc aggtcaatta atcatggaag caaatcttaa agggcatcgg
     9721 attggtggtg tggaagtttc cgaaaaacac gctggtttta tgattaatgt ggtagatggc
     9781 acagctaaag attatgaaga tttgattgct tatgtcattg agacagttga aaaccattct
     9841 ggtgtcaggc ttgaaccaga agttcggatt attggggaaa acctgtaacc attattgata
     9901 attaaagaaa gtaccgtgga ggatttatga caattgacta agccaattat cacatttaac
     9961 aatgtttcaa aaacatttga ggacagtgga acacaggttc taaagaacat taactttgac
    10021 cttgaagaag gaaaatttta caccctgctt ggagcttctg gctctggaaa atcaactatt
    10081 ttaaatatta tggcgggcct actagatgcc agcagcggag acatttattt agatggggaa
    10141 cgtattaatg atttgccgat taataaacgt gacattcata ccgttttcca aaattatgcc
    10201 ctcttccctc atatgactgt ttttgagaat gttgcctttg ctttgaagct gaagaaagtg
    10261 gacaagaaag agattgctaa gcgcgtgaaa gaaaccttga aaatggttca attagaaggg
    10321 tatgaaaatc gttctatcca gaagttatct ggtggtcaac gtcaacgtgt tgccattgcg
    10381 cgtgcgatta tcaatcaacc gcgtgtggtc ttacttgacg aaccactctc agcccttgat
    10441 ttgaaattaa gaacagagat gcaatatgaa ttacgtgaat tgcaacaacg tctaggcatt
    10501 acctttgttt ttgttactca cgatcaagaa gaagccttgg ccatgagtga ttgggttttt
    10561 gtcatgaatg aaggtgaaat tgttcagtcg ggaacaccag tggatattta tgatgagcca
    10621 attaatcatt ttgttgctaa ttttattgga gaatctaata ttattaacgg taccatgatt
    10681 gaagactatc ttgtctcctt taacgggaaa gaatttgaat ctgtggacgg tgggatgcgc
    10741 cctaatgagc ctgttgaagt ggttattcgt cctgaagatc ttcaaattac tttgccagaa
    10801 gaagggaaat tacaagttaa ggttgatacc caattattcc gcggggttca ctacgaaatt
    10861 attgcctatg atgaattggg taatgaatgg atgattcatt ctacccgcaa agctatcgag
    10921 ggagaagtta tcggattaga ctttacccct gaagatcttc atatcatgcg tcttaatgag
    10981 actgaagagg aatttgatgc ccgtattgaa gaatatgtgg aaatggatga gcctgaagat
    11041 ggattgatta atgccattga ggaggagcgt aatgaagaaa acctctagtc ttttttcgat
    11101 tccttacttc ttatggattc tcttctttgt tgtggcacca gtcactctct tgttttacaa
    11161 gtcctttttt gacatagaag ggcgcgtgac cttagccaat tatgaaacct tttttagctc
    11221 ttggacctat ttgagaatga gtgtgaattc tattttatac gctggtatta tcacactcgt
    11281 cacgctcttg atttcatatc ctacggctct ctttttaacg cgcctaaagc acaagcagtt
    11341 gtggcttatg ctcattattt tgccaacttg ggtaaactta ttgctaaaag cctatgcctt
    11401 tatgggaatc tttggtcaac aaggaggaat taacagcttt ttaaccttta tggggattgg
    11461 cccgcagcaa atccttttca cggatttctc cttcattttt gtagcctctt acattgagct
    11521 cccttttatg atgttaccga tttttaacgc tttggatgat attgaccata atgtcattaa
    11581 tgccagtcgc gacctaggag ctagtgaatt tcaggccttc tcaaaagtta tttttcccct
    11641 ttctttaaat ggggttaggg caggtgttca gtctgtcttt atcccaagtt tgagtctctt
    11701 tatgttaacc cgtttgattg gtggaaaccg cgtgattaca cttggtacag ccattgaaca
    11761 acattttttg accacccaaa actggggaat gggatcaacc ataggtgtgg tgttaatctt
    11821 aaccatggtt gctattatgt ggctcacaaa ggagaaaagt aaatgaaaaa atttgccaat
    11881 ctttatttag cgagtgtctt tgttttactc tacattccta ttttttattt gattttctat
    11941 tctttcaaca aaggtgggga tatgaatggt tttacaggat ttacccttga gcattaccaa
    12001 accatgtttg aggatagtcg tctcatgaca atcttactgc aaacctttgt tcttgctttt
    12061 agtagcgctc tactagcaac gattattggg acctttggag ctatctttat ccaccatgtt
    12121 agaggtaagt accaaaatgc catgctatca gccaataatg tcttgatggt atcaccagat
    12181 gtcatgattg gggcttcctt tttaattctt tttacatcat tgaagtttca gctgggcatg
    12241 tcttcagttt tattaagtca tattgctttt tcgattccta ttgtggtttt gatggtattg
    12301 ccgcgcttga aagagatgaa tcaagacatg gtcaacgccg cttatgattt gggagctaat
    12361 tatttccaaa tgctcaaaga agtcatgctg ccatacttaa caccagggat tattgcaggt
    12421 tattttatgg cctttaccta ttccttagat gattttgcag tgactttctt tttgactgga
    12481 aatggtttta ctactttatc tgttgagatt tattcgcggg ctcgtcaggg aatttccttg
    12541 gatatcaatg ctttgtcaac catcgttttc tttttctcca tcctcttagt gatcggttat
    12601 tattatatgt cacaggacaa ggaggaaaaa catgcgtaaa ctttattcct ttctagcagg
    12661 agttttgggt gttattgtta ttttaacaag cctttctttc atcttgcaga aaaaatcggg
    12721 ttctggtagt caatcggata aattagttat ttataactgg ggagattaca ttgatccagc
    12781 tttgctcaaa aaattcacca aagaaacggg cattgaagtg cagtatgaaa ctttcgattc
    12841 taatgaagcc atgtacacta aaatcaagca gggcggaacc acttacgaca ttgctgttcc
    12901 tagtgattac accattgata aaatgatcaa agaaaaccta ctcaataagc ttgataagtc
    12961 aaaattagtt ggcatggata atatcggtaa agaattttta gggaaaagct ttgacccaca
    13021 aaacgactat tctttgcctt atttctgggg aaccgttggg attgtttata atgatcaatt
    13081 agttgataag gcacctatgc actgggaaga tctgtggcgt ccagaatata aaaatagtat
    13141 tatgctgatt gatggagcgc gtgaaatgct aggggttggt ttaacaactt ttggttatag
    13201 tgtgaattct aaaaatctag agcagttgca ggcagccgag agaaaactgc agcagttgac
    13261 gccgaatgtt aaagctattg tagcagatga gatgaaaggc tacatgattc aaggtgacgc
    13321 tgctattgga attacctttt ctggtgaagc cagtgagatg ttagatagta acgaacacct
    13381 tcactacatc gtgccttcag aagggtctaa cctttggttt gataatttgg tactaccaaa
    13441 aaccatgaaa cacgaaaaag aagcgtatgc ttttttgaac tttatcaatc gtcctgaaaa
    13501 tgctgcgcaa aatgctgcat atattggtta tgcgacacca aataaaaaag ctaaggcctt
    13561 acttccagat gagataaaaa atgatcctgc tttttatcca acagatgaca ttatcaaaaa
    13621 attggaagtt tatgacaatt tagggtcaag atggttgggg atttataatg atttatacct
    13681 ccaatttaaa atgtatcgca aataagcact caaaaaggct ggtatttctc cagccttttt
    13741 aatgtatcga cagatgacgt caccagtaca cgcgataggg acgaccaacc ttggtaaaaa
    13801 tttgttggct gttcagttgc ttattttctt ctaaataagc aatgtattta cggacagaga
    13861 catgggataa gtgacaagcg gaagctaatt cttggatagt aaaaggttga tcaaaggctt
    13921 tgatattttc tataatccac tggaaagtgg attcagataa gcctttttct aacaattgtt
    13981 tgtttttagt gtcttttttg ctagtcaaac atttcagttg gtcaatttgg gcctgctcta
    14041 gttgctgatt ggccaaatgt tctcgatgcg taacaaactg ttggatgctt tcttgaaagc
    14101 gttcaaaggt aaagggcttg atgaggtagt cgataattcc taaatgaaaa ccatctcgga
    14161 taatattccc atcatttgcg gctgaaataa taatgacttc gcaaggaata tgctgagcac
    14221 gccatttctc caaaaattga atcccattgc catctgtaat atgaatatcc agtaaaatga
    14281 ggtcaattgc gtaatcagta agtatgcttt gaacagcttt catagagtcg ctggatataa
    14341 tgcgatcaaa aagatttagt ttttcgaggt aattgcgatg gataaaatcc accataggat
    14401 catcttcaat gattaaaacg ttcatgttgc catcctacat aaggtgttgt cactgagaac
    14461 tgtaactcgg ttacggtttg atgttgatgg aattgggaat ttgtatcggt caagagctgt
    14521 tgaaaataag gtaagtcaaa aataggctgt acccgctcca aatcaatcca attgtctgtc
    14581 aaggtgtaat ggctgattaa atgattctga tcatgttgaa tactcaaaac gagtgatttg
    14641 ggtctcagtg tggttagaag attagtatgg ataaagcggt aaatcatcaa accattatta
    14701 agttgattct tggtaacaga atgaggaatc tcgcttaaaa catcaatctt gagatggaca
    14761 tttaattctt ggtatttctc ttgctctcca atgagaaaac tagctagaag aggctcctta
    14821 acaaggacag ataagctagt gagaatttca ttttcgggct ccaaaatact gtctaaataa
    14881 attttcaatt ggtcataata agcaatatct actaagccat aaataacatg caattgattc
    14941 atgaatttat gagtttgggc ttgtagagca gaagcatagg cggtggtata ggctagctga
    15001 tccaaggtat caatagcctt aactgcttct cgcatgaaaa taatgtggcc tcggtgatcg
    15061 tttttgacac agatgggtga aatggctaac aagtagtctt cctcaccata ccgaaagagt
    15121 tgttcatgcc cctcttgcaa actaagtttt ggaaaatcag gaaagaggtg attgaaactg
    15181 ttgccagtag gttttcccaa ctggcatttt cgagcgatta actcttgtcc agcctgattg
    15241 cataattgta aaataccagt tttatctacc acaaatacgg cggcttcgat ttgatccaac
    15301 atggcattac gctcttcaaa gagctggtaa atttcacttg gttctaactg gtgcagttga
    15361 cgcttgagtc gaaaagaaat aaaactggtg accagtaaac taataagaag acaaaggaat
    15421 aaagacaggg tataattgcg ttttgacgtt aaagccacat catttagggt agttagttta
    15481 atgccaaccg caatagcacc aatctgtttg tcaccgtcaa acacaggtac tagatagcga
    15541 agtgactttc ctaaagtgcc cttggcggta gagataacct tttttcctgc tagaacagcc
    15601 tcctcatcac ctccttgaaa aggttttccg atatttttcg ggttaggacg ggtgagtcga
    15661 atccctttca tgttcatcac gaccacataa tcaaggttat agatggaggc aatggagttg
    15721 gtataggctg ttgttttagc atttggttgg ttgtttagga gtaattcttt aattgcttga
    15781 tgacttgcta acatttttcc agttgacgtt agcaaatggg tttcctgatt tttgatggat
    15841 tggtgcgtat catgtagcat aatcccgtaa aatagggagg ttgtgacaac aatcatagat
    15901 accaaaatca acgataaact ggcccataaa cgtagtggtt ttttcataag gtctcctctt
    15961 tattgagtat aacacgataa gaaatgacct gctagcttaa attaattaaa taacttgaaa
    16021 aaattaaagt agttaaacaa cttaaataaa ctatgctttt gacatgttct cttttatact
    16081 agtcttatca ctaaaggagg ttgtttcatg gaaacaataa gcaagaaaat gcctcaaaaa
    16141 gacttgtctg agcattcaaa agcatggcaa aataggcgaa taggctccgt tcccttgcct
    16201 gtttatctgg ttttagctac cttaattttg atcacaggct ggctccaaca attgcctgtt
    16261 aatatgctgg gtggctttgc tgttatttta acccttggtt ggctactagg aaccattgga
    16321 gcgaccattc caggcctcaa acattttggt ggcccagcta ttttatcact cttagtccct
    16381 tcgattttgg ttttttttaa tctcctcaac cccaatgtct tagaagcgac gaatgtcttg
    16441 atgaagcaag ccaattttct ttatttttat attgcctgtc tggtctgcgg tagtatttta
    16501 ggcatgaatc gaaaaatctt gattcaaggt ctttttcgga tgattattcc catgttactt
    16561 ggaatggttt gtgcaatggg tgtagggact ttggttggcg tcattttagg attagactgg
    16621 caacataccc tcttttatgt tgtgacgcca gtccttgctg gaggaattgg tgaaggtatt
    16681 ttacccttat ctcttggtta cagtgccatt acaggagtcg gaagtgagca attagtggct
    16741 caactgattc cagccaccat tattgggaat ttctttgcta tcttgtgcac ggctttgctc
    16801 aatcgttttg gagagaagca cccaagttat tctggtcaag ggcaactggt taaaattggt
    16861 cacagcgaag acatgtctga tgccctaaaa gacaattctg gagccctaga tgttaaatta
    16921 atgggggcag gcgttttaac agcttgttca ctttttattg ctggtggctt gttacagcat
    16981 ttaacaggtt ttccaggacc ggtgttgatg attattctgg cagccttctt gaaatacctg
    17041 aatgttattc cccaagaaac ccaaaatggt gccaagcaac tttataaatt tatttccagc
    17101 aactttactt ttccgttaat ggcagggctt ggactgcttt atatcccctt aaaagaggtt
    17161 gtggcaaccc ttagctggca atattttatt gtggtgatta gtgtggtgtt aacggttgtc
    17221 agtgtcggtt tctttgtctc tcgcttcctt aacatgaacc ctgttgaagc agctattatt
    17281 tcagcttgtc aaagtggtat gggtggaaca ggggacgtgg ctattttgag tacggctgac
    17341 cgcatgaatc taatgccgtt tgcccaagtc gctactcgtc taggtggggc tattaccgtt
    17401 atcaccatga cagctatttt aagaattatt tttagttaat ccaaaccaat aaaaaagaga
    17461 ggtatttcct atgaaaaatc aattaggtca acttgccctt gaacaagcta aaacgttcgg
    17521 aggtaaattg gaagttcaac caaaagttga cattacaaat aaacatgatt tgagcattgc
    17581 ctatacacca ggtgtagctg gtgtgtcatc tgccatcgca aaagataaaa cattagcata
    17641 tgacttaacc accaagaaaa atacagtagc cgttatcagt gatggtactg cggttcttgg
    17701 tctgggggat attggccctg aagcagccat gccagttatg gaaggaaaag cagccctttt
    17761 taaagcattt gcaggtgtcg atgctattcc gattgtatta gataccaaag atactgaaga
    17821 aattattagt attgtcaagg cgcttgcacc aacctttggt ggtattaatt tagaggatat
    17881 tagtgcgccc cgctgttttg aaattgagca acgcttaatt aaggaatgtc atattcctgt
    17941 tttccatgac gatcagcatg gaacagctat tgtggtgtta gcagccatct ttaatagttt
    18001 gaaacttctt caaaaatccc ttgatgaggt atccatcgtg gtgaacggtg gtggatctgc
    18061 gggattatcc attacccgta aattattagc agcaggtgct acgaaagtga cagtagtgga
    18121 taaatttggc attatcaatg aacaagaggc agatcagtta gcaccacacc atttggatat
    18181 agcgaaagtc actaatcgtg agtttaaatc aggtacctta gaagatgctc ttgaaggagc
    18241 agatatcttc attggcgtat cagcaccagg agtcttaaaa gcagagtgga ttagtaaaat
    18301 ggcagcgcgc ccagtaattt ttgccatggc caaccctatt ccagagattt accctgatga
    18361 agcccttgaa gcgggggctt acattgtagg tactggccgt agtgattttc ctaaccagat
    18421 taataatgtc cttgcctttc caggtatttt taggggagca ttagatgcac gggcaaaaac
    18481 cattactgtt gagatgcaaa ttgctgccgc aaaaggtatt gccagtcttg ttccaggtga
    18541 cgctttgagc actactaata ttattccaga tgcctttaaa gaaggagttg ctgagattgt
    18601 cgctaaaagc gtcaggtcgg tagtccttaa atcatagaat atatgaaaaa aagagaaagt
    18661 tatactttaa atcacaaaat aagtagaagc atatttctag cttctactta ttttgtgatt
    18721 agctaatatc attatcaata ataactttca agacatttag tagcatttca gttgtattgg
    18781 cattaacaag tccagtgttt aaggtgatat ttttaatcca taattcatcc aggttgaaat
    18841 caactggttt cccatgaacc ccaacgttag caatatgccc acctactgat ataatttttt
    18901 ggcaaatatc aaatgtcgcg ggataaccaa cacactccat ggaaatatcg acaccacgtc
    18961 cattggttat atcgtcaatg atagccttga cttcttcact acttcctgaa caaatcgtgt
    19021 gtgtggctcc aaacgtttta gctgcttcaa ggcgattttg agataagtcg accataataa
    19081 tattggctgg agagaaaagt tgaacggtta gtagggctgc gagtcctact ggaccggcac
    19141 caacaataca aacattatct ccaggcttga catgtgatgg caagacacca atttcatatg
    19201 aagttggtaa aatatcagaa agcatgacca gtgcctcatc atcaatcgta tcaggagcat
    19261 gatagagact accatctgca tgtgggatat ggacatattc tgcttgtgtt ccattaatta
    19321 aatggccaag aatccaaccg ccatcttcac aatgtgacga aaggcctcgt ttacaataat
    19381 aacaggtatg acatgatgtg acgcaagaaa taatcacttt atctccgatt ttaaagttag
    19441 tgaccgcatc accgatctcc ttaacaattc caattccttc aggaccaagg attgttcctt
    19501 ctttacatgc gggaacatcc ccacctaaga tatgcaaatc agttccacaa atagagtggt
    19561 ttttaccaac tggacgatat gtaggcttta taatgactgg ttttggtttg tctatgagct
    19621 gtagatttcc ggttgaaagg taagttgctg ctttcatatt taactcttta taaggttgag
    19681 aggtaatcaa ccaattcatt tttacacaga tattataata gtttaagaaa gggttttcaa
    19741 tattttttaa atcgattatg ataatttttt agatcatctt tgttgaataa cttcatcctt
    19801 attcagaact taaagggcac tattataaga atttgaaacc gctttactta aaccgtgtat
    19861 ttttgtacaa taatgattaa ggaggttttt agatgaaaaa agaatttacc agtatcctgt
    19921 ttacagttag tttttgtgga atcatagcat tgcctgtcga agctagtggc cctaaagttc
    19981 cttatacaca agaaggtata acggccattt caaatcaggc aacagtaaaa ttgatttcta
    20041 ttgctgatat cgcgagcagt ttagaaggac aaaaacctat aacggttagt tttgatatcg
    20101 atgatacttt gttatttact agccaatatt ttcagtacgg caaagaatat ataactccag
    20161 gctcatttga ttttttgcat aagcaaaaat tttgggactt agtcgctaaa cggggagatc
    20221 aggattctat tccaaaagag tatgcaaagc aactaatcgc aatgcatcaa aaacgaggag
    20281 ataaaattgt ctttattact ggccgaactc gaggatcgat gtataaaaaa ggtgagattg
    20341 ataaaacagc taagtcactg gctaaagatt ttaagttaga caagccaata gctatcaatt
    20401 atacaggaga taaagctgtg aagccgtatc agtatgataa aacatattat ataaagaaaa
    20461 acggctcaca aattcattac ggagatagtg atgaagatat aaatgctgcc aaagaggcag
    20521 gtgcaagacc tattcgcatt ttaagagctc ctaattcaac caatcttcct ttgccaaaag
    20581 ctggaggata cggagaagag gttttagaaa attcggctta ttagtcaaat atttgtgtaa
    20641 gaaaggaagt aacagtaatt tctttcatca ccccactgag taaccaatag cccagtgggt
    20701 tttttgggtt acagaaatca gttctaaaaa agaatcactg gtaacttaag gttgtctttg
    20761 atacaatggt aacagtgtat ttaaaagaaa gagaggataa catggaaaac cataaaaatg
    20821 aattcacctt ttccaacaaa tcaattattg cctatgtttg gcgtggtgtt atggttggta
    20881 ttattgctgg tgttattgtt agtttattcc ggttgttaat tgaagtgaca gctgactggg
    20941 tgattgaatg gtaccgatac gctcatatca attcgctgtt gctacttcct atactaagtg
    21001 tcagtttgtt agctgttctt tttgtaggtt ttttagtaaa gtctgattct gatataaaag
    21061 gatcagggat cccccatgtc gaaggagaac taaaggggct aatgtcccca gattggtgga
    21121 gtgtcctttg gaaaaaattt ttaggaggaa tcatggctat ttctatggga tttatgctcg
    21181 gtcgtgaggg tccttcgatt cagttaggtg ctatgtcagc caaaggatta gctaagtttt
    21241 taaaatcgag tcgtttggaa aagcgagtgc taattgccag cggagcagca gcagggctat
    21301 cagcagcttt taatgctcca atagcaggcc tcttgtttgt tgttgaagaa atttaccatc
    21361 atttttcgcg tttaatttgg attacagcgc tagtggctag cttagtggct aattttattt
    21421 ctctgaatat ttttggattg aaaccagtct tagcaatgtc agaggcgatg ccttttttag
    21481 ggctaaatca atattggttg ttgcttttac ttggattatt tctaggctgc ttaggctatt
    21541 tatatgagat agttatcctt aattttaata aactttatgt tattttaggg aattggttac
    21601 atctgccagc ttatttttac ggtattatta tggtttttct aattttaccg attggctatt
    21661 atttaccaca gttacttgga ggagggcatg gtttaatact ttctttatcc aatcaacaat
    21721 tgcctttgat gactatcttc ttttatttta ttattcgatt tattgttagt atgtttagtt
    21781 atggaagtgg cttacctgga ggtatttttt tacccatttt aactttaggt gctttggcag
    21841 gcctattatt tgggcaaata gcttctcaat taggtttatt gaaccaatct tttctttctc
    21901 tttttttgat attagggatg gcagggtatt ttgcggcaat ttcaaaagca ccactgacag
    21961 gcatgatttt ggtaactgaa atggtaggtg atttgaaacc cttaatggcc atagctgtag
    22021 ttacttttgt ctcctattta gtgatggatt tgttaaatgg acagccaatt tacgaagcta
    22081 tgctagataa gatggcaatg aagcatccaa ctaatcttgt tgaaccaaca ttaattgaat
    22141 tgactgttgg tgataagatt gcagggaaat atgttaaaga gttaaagctt ccagaaaatg
    22201 tcttaattac aacccaaatt caccatcaaa aatctcaagt tgtgtcaggt aacacgcgcc
    22261 ttttgtcagg agcaactatc tttttggtcg ttaatgaagc tgatacaggt tttgtccgtg
    22321 aggtattgat gtaggtatta atttatcaca attcggaaag ttcgagcttg tcttttagac
    22381 taagtcttcg aacgttttac tgctagagtt tcatctgaac caaagtgaaa cgcttttgat
    22441 gaagtcaagt aggctttttg ttatactaac aataaagata agctaaggag gctgagatgt
    22501 tagaaattgt ttcagaagag ctacgtcact atcaagaaca aaaattgatt gagtaccgta
    22561 acaaaaatca gttagcccca aaaggaggca ttgtatttgc aggtgattct ctcattgaat
    22621 tttttccttt aaaaaaagct tttggttcat gtttgcctat tattaatcga ggtattgctg
    22681 ggatagatag tcagtggtta ttgcgccatt tttctgtcca aattactgat ttagagccta
    22741 aacatatttt tttattaatt ggttgtaatg atatcgggct tggatatgat aaatgtcata
    22801 ttgtcaagac tattgtagag cttattagcc agattcgtag tcattgtgtc tacagtcaga
    22861 tttatctctt atctttatta ccagtttcca acaatccccg atatcagaag actgtcaaaa
    22921 taagaacaaa tgctatgatt gatgctatta ataaagattt agcaatgatt ccaactatag
    22981 aatttattaa tcttaatact tgtcttaaag acgaaaaagg tggtttatca gatgagaata
    23041 ctctagatgg tttacatctt aattttccag cttatgctaa actagctgaa attattcaag
    23101 cttatatcta gcaaataaat gtactaatag cgatgaggca agaagtcaga tagcagatgg
    23161 ttcatcaatc aattaagaaa aaagttatca agataccatt aaaaatagtt gctcaaagtt
    23221 ctttcaaatc aaaagattat gatatcgcta tgttgagttt tagtgtataa tgataattaa
    23281 aggagttacc atgaaatttg aaaaaaaaca agtcttctat ttagtcctta cgtttatctt
    23341 atgctatggg atcctagcaa actggcgaaa tggaacggct atcgtcacga ctatttacaa
    23401 aacaagcctt cctttttttt atggagcagc aggtgcctat attgttaata ttgtaatgag
    23461 cgcttacgaa aaggtatatg tttatatctt taaagactgg tcacatgtct taaaagtaaa
    23521 acggggtatt tgtttactgt tagcgtattt gacatttttt attttaatta cttggattat
    23581 ttccattgtc attccagact taattacaag tattagtact ctaacaaaat ttgatactat
    23641 aacgatacaa gaagttgtta acaatcttga gcacaataaa ctgttagcac gtactattca
    23701 gtatattggt ggcgatggca aacttacaga gacgattgct aactatagtc aacagttatt
    23761 aaagcaattt cttactgttt tgacaaatat tttaacatct gtcacggtta ttgcttctgc
    23821 aattattaat ctttttatta gttttgtttt ttcgttatac gttttagcaa gtaaagaaga
    23881 tctttgtcgt cagggaaata ctttagtaga tacttatact ggtaagtacg ctaaacgcat
    23941 tcattacttg ttagagttgt tgcatcagcg ttttcacgga ttttttgtta gtcagacctt
    24001 agaagctatg attttaggtt cgctgactgc tagtggcatg tttatattaa gattaccatt
    24061 tgcagggact attggcgttt tagtagcttt tacagcattg attccagtta taggtgcttc
    24121 aattggagca gctattggat ttattttaat tatgactcag tccatgtcac aggccattat
    24181 ttttatcatt tttttaatta ttttgcagca gattgaaggt aattttattt atccgaaagt
    24241 agttggtgga tcgattggat taccggctat gtgggtatta atggcaatta caataggcgc
    24301 ttctttaaag ggaatagttg gtatgattat tgcagttcct ttagcagcga cactttatca
    24361 agtgattaaa gataatattc aaaaaagaca agctattcaa aaaaaacaag tttcctaaaa
    24421 ggaacttgtt tttttgtcga ataaaaagat ggaggtaata tgataaatgt attctataaa
    24481 atgtgatgat aataaagcca tgccaagaga acgtttgatg cgactaggag cagagtctct
    24541 aagtaatcaa gaattattag caattttatt acgaacaggt aataaagaaa agcatgtctt
    24601 agagctgtca tcctatcttt tatcgcattt agacagtctg gcagatttta aaaagatgtc
    24661 tttgcaagaa ttacaacatt tggcaggtat aggaaaagtt aaagcgattg aaattaaagc
    24721 tatgattgag ttggtttccc gaattttagc gaccgataag acattaactg atagcgtatt
    24781 aaccagtgtt caggtcgctg aaaaaatgat ggcagcttta ggagataaaa aacaagagca
    24841 tttagtcgta ttgtatttag ataatcaaaa tcgtattttt gaagaaaaaa ctatttttat
    24901 tgggactgtc cgacgttcac ttgcagaacc aagagaaatt ttatactatg cctgtaaaaa
    24961 tatggcgact agtctcattg ttattcataa tcatccttca ggaaatattg aacctagttc
    25021 taacgattat tgctttactg aaaaaataaa acgatcatgt gaagatttag gcattatctg
    25081 tctagatcac attatcgtta gctataaaga ttattatagt tttcgagaaa aatcaaccct
    25141 tttttaaatc agaagtcatt gacgaataag cggaacaatt gtagatcttc atctcgaaca
    25201 ccttggagaa gttcaggatg ccactgaaca cctaaaaaag gaatggcatc gttggttgat
    25261 atgactgctt cgatggtacc atcacgtgga tctctagcga ttacttttaa atccttagca
    25321 atagttttta aactttggcg atgaaaagaa ttaattaatg tcttatgacc gtaaatagga
    25381 tataagatag agtctggctc aataatcatt tcgtgtgata agaaatcaga aggcgcttct
    25441 tgccaatgtg agtcaatgtg ttggttaaga tttcctccta aggcaacatt cattaactgt
    25501 gtaccacgac aaatccctaa gattggtttt tttaatgtta tagcctcctt gatgatagct
    25561 agctcaaatg tgtctcgctc tggtgaaaaa tcatcatcaa aagcagcctt ctcttcttga
    25621 taatattttg ggtcaacgtt ttgcccacca attaaaatga ttttatcaac catagataca
    25681 taagttttag cggcggcttc atcaccaatg ggtaaaagaa gcggcagccc cccagattga
    25741 gtgactgcct gtacaaatcc agtaggtgca tatgaccatg ggagattatc caaagccata
    25801 tttagtcttt gatttgcagt tattccaata atcggtttgg tcattatacc tccttaatct
    25861 agatgatttt gattcataaa atagagtagt gtctggagct cactggtcaa atcgacagat
    25921 tgaacaataa ctcctttagg aacttgtagg tgaacaggag caaaactcaa gattcctttg
    25981 attcctgctt caataagttg atcagtaact tcttgagcat gaatgctggg aaccgttaag
    26041 atagccgttt caatgtcagt gtttgcaatc cgttctttga cggatgagat accatggact
    26101 ggaatattat cagctgtttt agtaccaaca agagcgttat catcggtatc aaaacccatg
    26161 gcaatttgca tcttattacg atcatggaag cggtaatgta atagagcacg ccctatatta
    26221 ccgcatccaa ctaagataac gtttgttgta gagtgatcat taagcaagtc agcaaaaaaa
    26281 ttcatcaatt tggtaacatc atagccaaac ccacgacgcc ccaattctcc aaaataagaa
    26341 aagtcacggc gtacagtagc agagtcaatt cccattgcat ctgcaatttg tttagaactg
    26401 gctttttcaa cttggtcagc atggaatcgt ttaaaaatac ggtaataaag tgataagcgc
    26461 tttgcagtcg cttttggaat agatttgtca ataaccacta ttttactcct tgtagatttc
    26521 tcgttaaata tgtctgtctt tattgtaaca aaaagattgt gaaaaatgca acattttgat
    26581 tgtttttgta tgagttaaaa aagctaaaat tagtt
//
LOCUS       DATWEK010000022        26353 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.022, whole genome shotgun sequence.
ACCESSION   DATWEK010000022 DATWEK010000000
VERSION     DATWEK010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26353
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.022"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            57..1337
                     /locus_tag="VCR92_001152"
     CDS             57..1337
                     /locus_tag="VCR92_001152"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEP4268224.1"
                     /translation="MKLQKPKGTQDILPEDAAKWQYVESVARDTFSQYNYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGAANPATDVETIAMAYHLFEKLGIKD
                     VTLHLNSLGSPESRSAYRQTLIDYLTPMRDQLSKDSQRRLDENPLRVLDSKEKEDKLA
                     VEKAPSILDYLDEESQAHFEAVKDMLEALDIPYVIDTNMVRGLDYYNHTIFEFITSVE
                     GSDLTICAGGRYDSLVGYFGGPETPGFGFGLGLERLLMIIEKQGITLPIETEMDVYLA
                     VLGDSANSKALELVQAIRRQGFTAERDYLGRKIKAQFKSADTFKAKLVMTLGESEVEA
                     GKAVIKNNRSRQEVEVSFEDMMTNFANISEQLLS"
     gene            1675..3423
                     /gene="aspS"
                     /locus_tag="VCR92_001153"
     CDS             1675..3423
                     /gene="aspS"
                     /locus_tag="VCR92_001153"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEP4268225.1"
                     /translation="MKRSMYAGRVREEHIGTTITLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEEVSSDVMATAERLRSEYVIEVEGFVEARQQANDKLATGMVELKVSALTI
                     LNTAKTTPFEIKDDVEVSDDTRLRYRYLDLRRPEMLENFKLRAKVTHSIRNYLDDLEF
                     IDVETPMLTKSTPEGARDYLVPSRVSQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKETKEIDVTLPFPRMSY
                     DVAMNSYGSDKPDTRFEMLLQDLTVTVNGIDFKVFSEAPAVKAIVVKGNADRYSRKDI
                     DKLTEFAKQFGAKGLAWVKVTDGQLAGPVAKFLIAIETELSSQLKLAENDLVLFVADT
                     LEVANNTLGALRNRIAKDLDMIDQSQFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPT
                     PESAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKEMQERMFKALGFTADEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGKGNIREVIAFPKNNKASDPMTQAPSLV
                     SENQLEELSLQIESHD"
     gene            3416..4357
                     /locus_tag="VCR92_001154"
     CDS             3416..4357
                     /locus_tag="VCR92_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEP4268226.1"
                     /translation="MIKKTTYKKKVKYVISRGAKKVGLLHALRSISREKYAEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVFSALSHRLLGYDFPIAFAFYLINIPLLI
                     LAWYKIGHQFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGMGIGTGLKS
                     RISSGGTDIVSLTLRKRTGKDVGSLSLMVNGAILAFAGILFGWQYALYSMVSIFVSSR
                     VTDAIFTKQKKMQATIVTSHPERVIHMIHKRLHRGVTSINDAEGTYKHEQKAVLITIL
                     TCEEYPEFKWLMLKTDPQAFVSVAENVRIIGRFVEDD"
     gene            4377..5255
                     /locus_tag="VCR92_001155"
     CDS             4377..5255
                     /locus_tag="VCR92_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEP4268227.1"
                     /translation="MSIDQRLQLKKFCFIILGAAIYAFAFVYFYMANRIAANGLAGLT
                     LVGKALFEIDPSLIGYLINLPLVLLGARCFGKRAMVYTVTGVLSLYFFVWLFQRFPLV
                     VDLDHDNLVVSLMAGIIGGLGGGFVFRNGGTIGGADIIAKLLEDKLGLQLNQALLGID
                     LFVMIVSLTYISLPQMMYALIASFMYGQIVRLVQQGGYSARGIFIVSEQAEKIARFIM
                     EELGRGVTYLTGEGAYSGRRKKVIYVALGPRDIRELKAFLTQVDPNAFITYFDVNEVN
                     SPEFLTIKSKYHKKRK"
     gene            5298..6170
                     /locus_tag="VCR92_001156"
     CDS             5298..6170
                     /locus_tag="VCR92_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEP4268228.1"
                     /translation="MAHHDKLTKLLKLFLIALGVAIYTFGFVNFNMANALAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFILGAKIFGKRSLALTIYGTVLMSAFIWMWQKVPI
                     ELGLENDMMLVAVVAGLFSGIGSGIVFRYGATTGGTDIIGRIAEEKFGAKLGQTLLLV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKHSEAAAQAI
                     LTEINRGVTYLKGQGAYSGNDYNIMYVTLNPTEVREVKRILAGLDPDAFISIIDVDEV
                     ISSDFKIRRRNYDK"
     gene            complement(6197..6505)
                     /locus_tag="VCR92_001157"
     CDS             complement(6197..6505)
                     /locus_tag="VCR92_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEP4268229.1"
                     /translation="MPSEKEILDALSKVYSEQVIQADDYFRQAIFELASQLEKEGMSS
                     LLATKIDSLINQYILTHQFDAPKSIFDLSRLVKTKASHYKGTAISAIMLGSFLSGGPK
                     "
     gene            complement(6593..8284)
                     /locus_tag="VCR92_001158"
     CDS             complement(6593..8284)
                     /locus_tag="VCR92_001158"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEP4268230.1"
                     /translation="MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFS
                     LAKVLRKAPQMIASELAEQIDESQFEKVVAVGPYINFFLDKTKISSQVLEQVITAGSD
                     YAQQDEGQGRNVAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGDEAAVQAHPIDELLKLYVRINAEAETDPTVDEEAREWFRKLE
                     DGDKEATELWQWFRDESLLEFNRLYDQLHVTFDSYNGEAFYNDKMDEVLDLLEAKNLL
                     VESKGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAINR
                     AASQIEAKNPNLADKEAVAHSVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKADFTPSATTTYSLADAESWEIIKLIQDFPRIIKRTSDNFEPSIMA
                     KFAINLAQSFNKYYAHTRILDDNSERDNRLALCYATATVLKEALRLLGVDAPNEM"
     gene            8575..9012
                     /gene="argR"
                     /locus_tag="VCR92_001159"
     CDS             8575..9012
                     /gene="argR"
                     /locus_tag="VCR92_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEP4268231.1"
                     /translation="MNKMERQQQIKRIIQAEHIGTQEDIKNHLQKEGIVVTQATLSRD
                     LREIGLLKLRDEQGKLYYSLSEPVATPFSPEVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDILGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            9009..9361
                     /locus_tag="VCR92_001160"
                     /pseudo
     CDS             9009..9361
                     /locus_tag="VCR92_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623648.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RicAFT regulatory complex protein RicA family
                     protein"
     gene            9348..11903
                     /gene="mutS"
                     /locus_tag="VCR92_001161"
     CDS             9348..11903
                     /gene="mutS"
                     /locus_tag="VCR92_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEP4268232.1"
                     /translation="MAKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLIELGYKVAVAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
                     VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELT
                     AAGKLLQYVHKTQMRELSHLQALVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLY
                     WLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFIERTDLSNSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFDSPCVDKLVNDIDSLPELEY
                     LIRTAIDPDAPATISEGSIIRTGFDERLDHYRKVMREGTGWIADIEAKERQASGINNL
                     KIDYNKKDGYYFHVTNSNLSLVPEHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMCIRAQVETYINRLQKLAKILATVDVLQSLAVVAETNHYIRPQFNDNHVIT
                     IQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQM
                     GSFVAADHVDLPLFDAIFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDE
                     LGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHELTDLSTKLTSLVNVHVATLEK
                     DGDVTFLHKIAEGPADKSYGIHVAKIAGLPKSLLKRADEVLTRLETQSRSTEIISVPS
                     QVESSSAVRQGQLSLFGDEEKAHEIRQALEAIDVMNMTPLQAMTTLYELKKLL"
     gene            complement(12300..12953)
                     /locus_tag="VCR92_001162"
     CDS             complement(12300..12953)
                     /locus_tag="VCR92_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268233.1"
                     /translation="MWSSIFNFKENIVKKKLVMMLTLLISICAISVRANESGDLFTTI
                     GQSHLPGVTVAPFKTGDTTINVNLDPYGYVYGFVTSSNGNKIKKTENKTYEIPCSILE
                     KQDNPNCEGRKWTVSGNRADGGGNYTVQLEKPLAEGDKVTLSFADDGNLYFGQLVFED
                     GKTHNERLQKERDAEEQQYAEVLFKRSIEEESKKTWHQRLSDSIQDQWWNFKDWLRG"
     gene            complement(13118..13501)
                     /locus_tag="VCR92_001163"
     CDS             complement(13118..13501)
                     /locus_tag="VCR92_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEP4268234.1"
                     /translation="MSKKNAIRKLKEFHRWQRIANSLDLTYTELYQFDIEYHPTRRKH
                     LEISRECALEELDAIRYAINQLSKVEYRQILIECYLISEEKTQQDIMEELNRSQSWYY
                     ESKKRALLEFVEFYRDGALKNNVRL"
     gene            complement(13476..13838)
                     /locus_tag="VCR92_001164"
     CDS             complement(13476..13838)
                     /locus_tag="VCR92_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEP4268235.1"
                     /translation="MSAKEQLKELKPLFALITLFEEQRDKDIELINAFHNPEAIRHIE
                     KGTAKQLLYLAKERDKRLAMIATLQDERQIAVIKARYVDDLSWDEILDKLGYSRNIVF
                     KLHREALEVLDEQEERYS"
     gene            complement(14243..14731)
                     /locus_tag="VCR92_001165"
     CDS             complement(14243..14731)
                     /locus_tag="VCR92_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268236.1"
                     /translation="MLELSIENIIKPMKTQGKTRVTGSIGDQAIRIDLDGLVIHYNGQ
                     GLLLETIPGTYGGKRYFFVCPDCERRCRKLFKASHAFACGSCQKVHQATLNRSKTDCC
                     YYWQLAFKECLKVNPEARHIHGYYSRDDFPKRPKYMRLTKYLYHWRRFHYYMDKGDRY
                     WL"
     gene            complement(14805..15314)
                     /locus_tag="VCR92_001166"
     CDS             complement(14805..15314)
                     /locus_tag="VCR92_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001258765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268237.1"
                     /translation="MRTFSDTPKTFTFHYTFKDFDTAQVACHAILGYMTGTYEQPVID
                     ATYHNDDQGGHANQLVLKYVEDRKLNKVFKRICDSFKDYYNQPEDMTDEELDHQRVVS
                     LSKSTQGKVNNRDTLIAFISDHNQLAEHLSMNYKEMTPEDLGAILESISQAFNHLYDM
                     VVEGQLLVK"
     gene            complement(15316..15489)
                     /locus_tag="VCR92_001167"
     CDS             complement(15316..15489)
                     /locus_tag="VCR92_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001873750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268238.1"
                     /translation="MKLKLHTRGGNTITIQGDRTLYNELVKYLLSGEQPNWVASPSAI
                     INLSDIIAITKEK"
     gene            complement(15495..15668)
                     /locus_tag="VCR92_001168"
     CDS             complement(15495..15668)
                     /locus_tag="VCR92_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2758 domain-containing protein"
                     /protein_id="HEP4268239.1"
                     /translation="MKIKLFYQKHNESLDDFEHRVNLFTLSVSVIDIKFQEATYGNYE
                     DMDSRTGLLVLYR"
     gene            complement(15665..15919)
                     /locus_tag="VCR92_001169"
     CDS             complement(15665..15919)
                     /locus_tag="VCR92_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268240.1"
                     /translation="MNPNYTNHGVKKMRYNYDDLPNDQLYRLELPNGQCGYDFITKIN
                     FNIKSRPGDCDFTRPELTRRGYQWVFDCGFAIPVEKGAKT"
     gene            complement(16213..17607)
                     /locus_tag="VCR92_001170"
     CDS             complement(16213..17607)
                     /locus_tag="VCR92_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence-associated protein E"
                     /protein_id="HEP4268241.1"
                     /translation="MKDYQNKLSQATQPAFAPAFRTRKGRGDKEYVISSPYNVGKVFE
                     FYENIYTGIKYNEFEKTIEITKAVPWSKEKGLWTNEQTSLCIAFIDEKYRFTPRKEHI
                     EVAITALAKKNTYHPIKQRIESQKWDGKARGERYFIDLLGCADNSYNREIAKVWLTGL
                     MARIYLRKVKFEVVPILIDKRQGTGKSTVTKRLLPSYHTDSEIKFGKNDSDYQKIQAN
                     AIIELGELKGMSKAEIETVKSFISSDSDTYREPYERKATPHPRHCVFIGTANKKSFLK
                     DSGTERRFFPIECGINDVKKHPMEVEEDYFLQVLAEAKVWFNNYEPLTPSKELMNQLA
                     DIQEDYKVEDVDKEIIDQLLNEFQIVEGWDSLSQYEQRQYILKQLGEPLDNAQSYSDY
                     PSAQTDCLLQVTSPNHIAYLGFNQKPTQGGKALISQKIRDYLDNDDGWKKGENPARKR
                     LFKGGTPVPYYERV"
     gene            complement(17619..18485)
                     /locus_tag="VCR92_001171"
     CDS             complement(17619..18485)
                     /locus_tag="VCR92_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEP4268242.1"
                     /translation="MAIYEARGFSSYLYPYKGPLEPFDYVAQFRPLKPPEDIDIEEYK
                     RTQAPYCLSGKVTAEKNGSYKRNNASLVYRDLIFLDYDEIETGVNLPKIVSQTLWEYS
                     YIIYPTIKHTPEKPRYRLVMKPSDVMTEATYKQVVKEIADKIGLPFDLASLTWSQLQG
                     LPVTTGDPEDYQRYVNHGLDYPVPKNGSTPNRQVVTTYTPRPRSQRSITMRVIDTLFN
                     GFGDEGGRNVALTKFVGLLFNKWVDCDLETAYELVQIANSVTTKPLPIDEIDTTFRSI
                     LDKELRKRGIKP"
     gene            complement(18486..18758)
                     /locus_tag="VCR92_001172"
     CDS             complement(18486..18758)
                     /locus_tag="VCR92_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268243.1"
                     /translation="MNVFSQDYEAKLLEQNLTAFNHFLEAYQKPKPRVLGLITAEQVK
                     EELNIKGKTLKRWENAGLRRYQPPLEDTRKHYYKVSDILIFLGVNV"
     gene            complement(18761..19090)
                     /locus_tag="VCR92_001173"
     CDS             complement(18761..19090)
                     /locus_tag="VCR92_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268244.1"
                     /translation="MTLPENYRRVLNLIKVGADNPITGAEISLILKLEERSVQSIISS
                     LITRYNVPIIGIRHGFNRGYFIPANKEELLDGAKAFYNQVQKEQERLSVLLNADLTSY
                     KELLKGG"
     gene            complement(19102..19293)
                     /locus_tag="VCR92_001174"
     CDS             complement(19102..19293)
                     /locus_tag="VCR92_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268245.1"
                     /translation="MQELNLTPTQTLILFFVLGLLGLLLSRSKPLIEIDLPEDTHAPK
                     PRQNANYGAYIQAQNHYYN"
     gene            complement(19293..19625)
                     /locus_tag="VCR92_001175"
     CDS             complement(19293..19625)
                     /locus_tag="VCR92_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268246.1"
                     /translation="MKYRVETNPFSKDRYTPEQLEMFKNRQLSKDKAEVYFTRLYNQH
                     IAWVIIANVMTEYVIKFRKSATSFEEAWDALDYQRTTEIVFRAVNGLPCSEKDSGELE
                     TYLSEVSA"
     gene            complement(19727..20179)
                     /locus_tag="VCR92_001176"
     CDS             complement(19727..20179)
                     /locus_tag="VCR92_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000916929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268247.1"
                     /translation="MLKNQDNMIKKKRNPRVLFRNVAYKLSEIEGKTLTEIASFLGFG
                     NSEVCRSTLYKWKRKKWLKFDLKNGHYRNVEVLHEVTLEKMANKELKEQGLIYKANIY
                     YEQVVSTSEIIEDIKTKTQDRIKAIHLQQKALERIPSELFAELYTNMN"
     gene            complement(20320..20493)
                     /locus_tag="VCR92_001177"
     CDS             complement(20320..20493)
                     /locus_tag="VCR92_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEP4268248.1"
                     /translation="MSPKMGRPVKGTAKRDKRLEVRLTADEYNTIQETADKNGLSKAD
                     LIVKAVNSYESEK"
     gene            complement(20711..20884)
                     /locus_tag="VCR92_001178"
     CDS             complement(20711..20884)
                     /locus_tag="VCR92_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000132665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEP4268249.1"
                     /translation="MTDTKKRVGRPKGENSNTVKLTVRVSEELDSKLNKYAKENNLTK
                     PETLRKAFENLTK"
     gene            complement(21132..21659)
                     /locus_tag="VCR92_001179"
     CDS             complement(21132..21659)
                     /locus_tag="VCR92_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEP4268250.1"
                     /translation="MTMRYLLEAFGVLSFEIHKPEKGSLGGRPRRIYHLNEQQATLLV
                     TYLGNTEPVREFKKNLVKAFFEMREELTQIRLQRSLEAPKRKTLNEAIKTWEHAPKMA
                     YPTVYNLLLKAVTGKNSKQLKVTRGGYSDIDCLNSIELAQYTALEDMAIALINLNFTY
                     QDIKTMALKNTLQCA"
     gene            complement(22071..22478)
                     /locus_tag="VCR92_001180"
     CDS             complement(22071..22478)
                     /locus_tag="VCR92_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268251.1"
                     /translation="MARTPFTQELLHQIFDDTGTMSLELIAERLPDWSEKDIKLRLAA
                     WRYRNNIDYTMANGEIDTFEIINNRKAISEEVSAGRQLKLEEYFKQVQATAEIINKPT
                     ASDTNRLKAIQLQQVAMDEIPDQYFKELTELYG"
     gene            complement(22499..22699)
                     /locus_tag="VCR92_001181"
     CDS             complement(22499..22699)
                     /locus_tag="VCR92_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4268252.1"
                     /translation="MTVGDKIKTIRLNLGETMEEFGKRFGTSKGTVNNWEKGRNLPNR
                     NSLLRIAQLANQTVSDFLAITD"
     gene            complement(22733..22939)
                     /locus_tag="VCR92_001182"
     CDS             complement(22733..22939)
                     /locus_tag="VCR92_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4268253.1"
                     /translation="MTQITLKAARINAGYTLKQVAGAVGKNPQTISKYEKDSSDISLG
                     LLQKLSSLYGVTIDNLFLGKKVRK"
     gene            23093..23860
                     /locus_tag="VCR92_001183"
     CDS             23093..23860
                     /locus_tag="VCR92_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP4268254.1"
                     /translation="MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTI
                     TGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSNNIETNSNIIPSTLQKVTSTLSQ
                     LEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
                     PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVIND
                     SGAFLHSLNDKYDDILIDRDSDFRIIGEVIGSFTSKS"
     gene            complement(24722..24865)
                     /locus_tag="VCR92_001184"
     CDS             complement(24722..24865)
                     /locus_tag="VCR92_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEP4268255.1"
                     /translation="MSGGGAYVCKSQKPKERRRQGLSVYETLTLMIAFGTLIVAIMNN
                     KNK"
     gene            25114..26265
                     /locus_tag="VCR92_001185"
     CDS             25114..26265
                     /locus_tag="VCR92_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEP4268256.1"
                     /translation="MIMKITEHKKKNGTIVYRASIYLGIDQMTGKRVKTSITGRTRKE
                     VNQKAKHAQFDFLSNGSTIKRKVVIKTFKELSHLWLETYKLTVKPQTYDATVTRLNRH
                     IMPTLGNMKVDKITASDIQMLINRLSKYYVNYTAVRSVIRKVLQQGVLLGLIDYNSAR
                     DIILPRKQPNAKKKVKFIDPSDLKSFLEHLETSQHKRYNLYFDAVLYQLLLSTGLRIG
                     EACALEWGDIDLENGTIAINKTYNKNLKFLSTAKTQSGNRVISVDKKTLRSLKLYQMR
                     QRQLFNEVGARVSEVVFATPTRKYFNASVRQSALDTRCKEAGIERFTFHAFRHTHASL
                     LLNAGISYKELQYRLGHANISMTLDTYGHLSKDKEKEAVLYYEKAMNNL"
BASE COUNT         7625 a         4816 c         5229 g         8683 t
ORIGIN      
        1 atataagaaa aaatggtaga atgtttaaag agaaaactaa tcaaagaggt aaacttatga
       61 aacttcaaaa accaaaagga acccaggata ttcttcctga ggatgctgcg aaatggcagt
      121 atgtggaatc tgttgcgcgt gatacgttta gccaatacaa ttatggagaa attcgtactc
      181 ctatgtttga acactacgag gtaatctcgc ggtctgtggg tgatacgact gatattgtga
      241 cgaaggaaat gtatgatttc tatgataaag gagatcgtca cattaccttg cgaccagagg
      301 gtacagctcc agtggtacgt tcttatgttg aaaataaatt gtttgcgcca gaggtccaaa
      361 aacctgtcaa actttattat atcggttcca tgttccgcta cgaacgccct caagctggtc
      421 gtttacgtga atttcaccaa attggagtag aatgtttcgg tgctgctaat ccagcaacag
      481 atgttgaaac cattgcgatg gcctatcacc tctttgaaaa attgggtatt aaggatgtca
      541 cccttcattt aaatagtttg gggagccctg agagtcgttc agcttatcgt caaaccttga
      601 ttgactactt aacaccaatg cgtgatcaat tatctaaaga tagtcaacgt cgcttggatg
      661 aaaacccact gcgcgtgctt gattctaaag aaaaagaaga taaactagcc gttgaaaagg
      721 cgccttctat tttggattac ttagatgagg aaagtcaggc gcactttgag gcggtcaaag
      781 atatgcttga agcacttgac attccttatg tgattgacac caatatggta cgtggccttg
      841 attactataa ccacactatt tttgaattca tcacgtctgt ggagggctct gacttaacca
      901 tctgtgcggg tggacgttat gatagtttgg taggttattt tggtggacca gaaacccctg
      961 gctttggctt tggtcttggt ttagaacgtc tcttgatgat tattgaaaag cagggcatta
     1021 ccttgccaat tgagacagag atggatgttt accttgctgt gttaggtgat agtgctaata
     1081 gcaaagcttt agaattggtt caagccattc gccgtcaagg gtttacagct gaacgagatt
     1141 accttggccg taagattaag gctcagttta aatcagccga tacctttaaa gcaaaattgg
     1201 taatgacttt aggagaaagt gaagttgaag caggcaaagc tgtgattaag aataatcgta
     1261 gtcgtcaaga agtggaagtc agttttgaag atatgatgac aaactttgca aacatctcag
     1321 agcaattatt gtcttaatga ttttattgtc gtcataagct tttgttgata tgattgttta
     1381 gaagataatc actaaaacag gtgtaacttc cctttttaga agggagttgc acctgtttgt
     1441 tttctgtaag gggattgatt agctttctta gtattctgtg aggacacctg atatgtcaaa
     1501 atgctgacga ctcagtattc ttgctttatc tttagaaaaa ctctttttaa atgggtgggg
     1561 tttttaaggg ctttttgcta taatagtagg gaatgaatta attgatttat atagtgaaag
     1621 gaattggaaa cgagcaggtt tcacaggatt ctgtttgttt tagggaattt atttatgaaa
     1681 cgtagcatgt atgcagggcg tgttcgcgaa gaacacattg gaacgacaat cacattgaaa
     1741 ggatgggtca gtcgtcgtcg tgacttgggt ggtctcatct ttattgattt acgtgaccgt
     1801 gagggtgtga tgcaattagt cattaaccct gaggaagttt ccagtgatgt gatggcaact
     1861 gctgaacgcc tacgtagtga atatgtgatt gaagtggaag gttttgttga agctcgacaa
     1921 caagccaatg ataagttggc gacaggaatg gttgagttaa aagtatctgc tttgaccatt
     1981 ttaaacacag ctaaaacgac gccttttgaa attaaagatg acgttgaagt aagtgatgac
     2041 acgcgtttac gttaccgtta cttagattta cgacgtccag aaatgttaga aaacttcaag
     2101 ctacgtgcaa aagtgactca ttctatccgt aattaccttg atgaccttga gtttattgat
     2161 gtcgagacac ctatgttgac aaaatcaact ccagaaggtg cgcgtgacta tctggtacca
     2221 agtcgtgtta gccaagggca tttctatgct ttgccacaaa gtccgcaaat taccaaacag
     2281 ttattgatga atgctggctt tgatcgctat tatcaaattg tgaaatgttt ccgcgatgaa
     2341 gatctacgtg gtgaccgtca acctgagttt acacaagttg acttggaaac gtcattcctt
     2401 tctgaacaag agattcaaga catcgttgaa ggcatgattg ctaaagtgat gaaagagaca
     2461 aaagaaatag atgtaaccct accattccca cgtatgagct acgatgtagc aatgaatagc
     2521 tacggctctg ataaaccaga cacacgtttt gagatgcttt tacaagactt gacagtaact
     2581 gtcaatggaa ttgacttcaa ggttttctca gaagcaccag ctgtcaaggc gattgtggtg
     2641 aagggaaatg cagatcgata ctctcgtaaa gatattgaca aattaactga atttgccaaa
     2701 caatttggtg ctaaaggcct tgcctgggtt aaggtgacag atggtcaatt ggcaggccca
     2761 gtagccaagt tcttgatagc tattgagaca gagttgtcaa gccaattaaa acttgctgag
     2821 aatgatttgg ttttatttgt agcggatact cttgaggttg ctaataatac attaggtgcg
     2881 cttcgtaatc gtattgccaa ggaccttgac atgattgatc agtcgcagtt taatttcctt
     2941 tgggtggttg attggccaat gtttgagtgg tcagaagaag aaggacgtta tatgtcagct
     3001 catcacccct tcactcttcc aacgccagaa tctgctcatg agttagaggg tgatttggct
     3061 aaggtacggg caattgctta tgacatcgtt ttaaatggtt acgagcttgg tggtggtagc
     3121 ctgcgtatca atcaaaaaga gatgcaagag cgcatgttca aggctcttgg ctttaccgct
     3181 gatgaagcta acgaccaatt tggtttctta ctagaagcga tggactacgg ctttcctcct
     3241 catggtggct tggcaattgg tcttgaccgt tttgtcatgt tgcttgctgg aaaaggcaat
     3301 attcgagaag ttattgcctt ccctaaaaat aacaaagcct ctgatccaat gacgcaagca
     3361 cctagtcttg tttctgaaaa ccaattagaa gaactcagtc ttcaaataga aagtcatgat
     3421 taagaaaaca acctataaga aaaaagttaa atatgtcatt agtagagggg ccaagaaagt
     3481 tggcctactc cacgctctaa gaagtatttc aagagaaaaa tatgcagaga agatttcggc
     3541 ttctctgctt tatggcattc tctctagtat tgctgtgaat tttttcttcc agcctgggca
     3601 tgtttattca agtggagcaa ctggtctagc acaggttttt tcagctctta gtcatcgtct
     3661 tttaggctat gattttccca tcgcctttgc gttttatttg attaatattc ctttgcttat
     3721 tttagcttgg tataaaattg ggcatcaatt taccattttt acctttatca cagtcagcat
     3781 gagttctttc tttattcaaa tcatgcctca agtgacgctg acgactgatc ctcttatcaa
     3841 tgctattttt ggtggtttgg ttatgggaat gggaattggt acaggtctca aatcacgtat
     3901 ctctagtggg gggactgata ttgtcagttt gacccttaga aaacgaacag gcaaggatgt
     3961 gggcagtctc tcattgatgg ttaatggtgc aattttagcc tttgcaggga ttttatttgg
     4021 ctggcagtac gccctttatt ctatggtctc tatctttgta tcaagtcgtg ttacggatgc
     4081 cattttcacc aagcaaaaga aaatgcaggc aactattgtt accagccatc cagagcgtgt
     4141 gattcatatg atccataaac gtctgcatcg cggggtgacc agtatcaacg acgcagaagg
     4201 gacttacaag catgaacaaa aagcagtttt gattaccatt ttgacatgtg aagaataccc
     4261 agaattcaaa tggctgatgt taaaaacaga cccacaagcc tttgtttcag tggctgagaa
     4321 tgttagaatt atcggtcgtt ttgtggaaga tgattaagaa aaacacagga ggtgtcatgt
     4381 caattgacca acgtttacag ttaaagaaat tttgctttat tattttagga gctgctatct
     4441 acgcctttgc ttttgtttat ttttacatgg ctaatcgcat tgcagccaat ggtttagctg
     4501 gtctcaccct agttggtaag gcactttttg agattgatcc ttctttgata ggctatttga
     4561 ttaatttgcc tttggtcttg ctgggagcta gatgttttgg gaaaagagcc atggtttaca
     4621 cagtaacggg tgttttatca ctttactttt ttgtgtggct gtttcaacgc tttcctttgg
     4681 tcgttgactt ggaccatgac aatttagtcg tttccttgat ggctggaatt attggtggtc
     4741 taggtggcgg ttttgtgttt cgcaatggtg gaaccatcgg tggagcagat attattgcta
     4801 agttattaga agacaagtta ggactacagc tgaatcaagc tcttttaggc attgatcttt
     4861 ttgtcatgat tgtctctttg acttatattt ccctgccgca aatgatgtat gctctgattg
     4921 ctagctttat gtatggtcaa attgttcgct tggtacaaca aggtggttat tcagcccgtg
     4981 gcatttttat cgtttcagaa caagcggaga aaattgcccg gttcatcatg gaagaattgg
     5041 gaaggggagt tacttatcta acaggtgaag gagcctactc tggtcgccgt aaaaaagtga
     5101 tttatgtggc tttggggcca agagatatta gggaattaaa agctttttta actcaggttg
     5161 atcctaatgc ctttatcact tattttgatg ttaatgaagt taatagccca gaatttttaa
     5221 ctattaaaag caaataccat aaaaagagaa aataaatgag cattagagtt gcctgcgaag
     5281 aatagtgagg ataaaggatg gcacatcacg ataaattgac taaactacta aaactgtttt
     5341 tgattgccct aggtgtagcc atttatacct tcggttttgt taattttaac atggctaatg
     5401 ctttggctga aggtggtgtg gcaggaataa ccttgatttt acacgcgcat tttgggatta
     5461 atcctgctta ctcttctctc ttatttaatc ttccactttt tattttaggg gcaaagattt
     5521 ttgggaagcg ttctttggct ctaaccatct atggaacagt tctgatgtcc gcttttatct
     5581 ggatgtggca aaaagttcct atcgaacttg gcttggaaaa tgacatgatg ttggtggctg
     5641 tagtggcagg tctcttttca gggattggga gtggcattgt ttttcgctat ggtgcaacca
     5701 caggtggaac ggatattatt ggtcgcattg cagaagaaaa atttggagct aagctaggtc
     5761 aaactttgct tttggtggat gctcttgtat tgacagcttc gttgacttat gtggatttaa
     5821 aacacatgct ttatactttg gtggcaagct ttgtttttag ccaaatgatt agtgtggttc
     5881 aaaatggtgg ttacactatc cgtggaatga ttattattac caagcattca gaggctgccg
     5941 ctcaagctat cctaaccgaa atcaatcgtg gagtgactta cttgaaaggt caaggagctt
     6001 actctggtaa tgattacaat atcatgtatg tgaccttgaa cccaactgaa gttcgggaag
     6061 tcaaacgtat tttagctggt ttggatccag atgcctttat ctccattatt gatgtggacg
     6121 aagttattag ctctgatttt aaaattcgcc gaagaaatta tgataaataa aaatacaggt
     6181 caaacagcct gtatttttat tttggtcccc cacttaagaa actaccaagc ataatagctg
     6241 atatagcagt tcccttgtaa tggctagctt ttgtttttac caagcgacta agatcaaata
     6301 tgcttttagg agcatcaaat tgatgtgtta agatgtattg attgataagt gagtcaattt
     6361 ttgtagctag gagtgagctc atcccctctt tttcaagttg actggcgagc tcgaagatcg
     6421 cttgacgaaa ataatcatcg gcttgtatta cttgttcgct ataaacttta ctaagagcat
     6481 ctaatatttc tttttctgat ggcatggcat tctcctgtaa catattgtgc tattattata
     6541 atataaaaaa ctaagactgt cataaatgtg acagccttag taatgttatt acttacattt
     6601 catttggtgc gtcaacaccg agtaagcgaa gcgcttcttt aagaacagta gcagttgcat
     6661 agcagagagc taagcggtta tcacgttctg agttgtcgtc aagaatgcga gtgtgagcat
     6721 aatatttgtt aaagctttgg gctaagttaa tagcaaattt agccataata gaaggctcaa
     6781 agttatctga tgttcgcttg ataatgcgtg ggaaatcttg gataagtttg ataatttccc
     6841 agctttcagc atcagctaaa ctgtaagtgg tggttgcaga tggcgtaaag tcagctttac
     6901 gtagaataga ttggatacga gcatgagcat attgaacgta aggtccagtt tctccttcaa
     6961 aggaaaccat ggcttcaagg tcaaagtcat acccattcat acgatctgtt ttgagatcgt
     7021 aaaacttgat ggcaccgaca ccaacagagt gtgcaacggc ttctttgtca gcaaggtttg
     7081 gatttttcgc ttcaatttga gaagctgcac ggttaatggc ttcagcaacc gtaggttcaa
     7141 gaagaataac attaccttta cgtgttgata atttagcacc gccttttgtg acaagtccaa
     7201 aagcaacgtg tgtcatatca tctgaccaat cgtaacccat ttcttttagc actgctttta
     7261 attgtttgaa gtgagcagct tgctcattac caacaacata aacggattta gcaaagtcat
     7321 aagtgcgttt acggtaaagt gcggcagcta ggtcacgggt aatgtaaaga gtagcgccat
     7381 ctgatttttt gatcaaggca gggtgttcaa tgccatattt ttcaagatta acaacttggg
     7441 cacctttaga ttctacaaga aggtttttag cttctaataa gtcaagaacc tcatccattt
     7501 tgtcattata gaaggcctca ccgttgtaac tatcgaaggt gacatgtaat tggtcataaa
     7561 gtcggttgaa ctcaagtaaa ctttcatcac ggaaccattg ccataattca gtagcttctt
     7621 tgtcgccatc ttccaattta cggaaccatt cacgagcttc ttcatcaacg gtgggatcag
     7681 tttcagcttc agcattgata cgaacgtaaa gttttaagag ttcatcaata ggatgtgcct
     7741 gaacagcagc ttcatctccc cattttttgt aggcaacaat gagcatacca aattgtttac
     7801 cccagtcacc aaggtgattg atttttacag gtttatagcc cattttggca aaaatgtgag
     7861 cgagactatc accaataact gttgagcgga ggtgaccgat tgaaaatggc ttagcgatgt
     7921 ttgggcttga catgtcaata gcaacatttc gcccttgacc ttcgtcttgc tgagcatagt
     7981 ctgaacctgc tgtaatcact tgttcaagga cctgtgagga aatcttagtt ttatcaagga
     8041 aaaagttgat gtaagggccg acagctacga ctttttcaaa ttggctctca tcaatctgtt
     8101 cagctaactc gctagcaatc atttgagggg ctttgcgaag gacttttgct aaactaaagg
     8161 ctggaaaggc aaggtctccc atgtcagaat tttttggggt ttcaagcaag ttaaaaatag
     8221 catcttgttc taattctgga acaactttag ctatttcact tgcgattaga gttttagtat
     8281 ccatacagcg tctcctaaaa attgtttgtc accctattct aacatatttc tttaaaataa
     8341 acgaggagag gattgataaa ttatactgaa actttcaagg aaatgaattg cttgaggttg
     8401 ttgtttttct gaaaatgtta taaaaagaga aatgaggttt cttttcaaca gttttcaagt
     8461 gaaattctag ttgaatttgc taaaaaattg ctgaaaatag ctgggcgaag atgaaataat
     8521 acactttttt tgttataatt tgagaggata attatacaat tggggtgata tatcatgaat
     8581 aaaatggagc gtcaacagca gattaagcga atcattcaag cagagcatat tggcacacaa
     8641 gaagatatta aaaatcacct tcaaaaagaa ggcattgtgg tcacccaagc aactctatct
     8701 cgggacttaa gagaaattgg ccttttgaaa ttgagagatg aacaaggcaa actctattat
     8761 agtttgtctg aacccgttgc aacaccattt agtcctgagg tgcgttttta tgttttgaaa
     8821 gttgatcgag caggttttat gctggttctc cataccaatt taggagaggc tgatgttcta
     8881 gctaatttga ttgacaatga tgccattgaa gatattctag gaaccattgc tggtgcggat
     8941 accttgcttg tgatttgcag agacgaagag attgctaaac gctttgaaaa agatttggct
     9001 gcaggcctat gactagctat taagagtctt tgacacaatt gattcttgct atccatgaat
     9061 tctagtatcg ttgcttataa agaagtgcag caatagctgt ctaagctccg tgattttaaa
     9121 aagtaagctt atcagatgaa acgctatcaa caagatgccc tgcttttcaa aaaaaataga
     9181 taaagaaaag gctgcgacag tatctgcaag cagggcaaaa gaactagaag ataggctcag
     9241 tcatcagcca ttaattgatg attatcgaga aaagatgcaa gatgcaagtg atgtgattca
     9301 gtatatcacc aaacgtatag aagatcagtt aaacaaggag ttaacaaatg gcaaaaacta
     9361 acatttctcc tggaatgcaa cagtatctgg acatcaaaaa agattatcca gatgcttttt
     9421 tgctttttag gatgggtgac ttttatgaat tattttacga ggacgctgtc aaagcagcac
     9481 aactcttaga aattggtttg accagtcgca acaagaatgc ggaaaatcca attcctatgg
     9541 caggcgtgcc acatcattct gcccaacaat acattgatgt gttaattgag ttgggttaca
     9601 aggttgctgt cgcagaacaa atggaagacc caaagcaagc tgttggggtg gtgaagcgtg
     9661 aggtcgttca agtcataact cctggaacgg ttgtggattc agctaagcca gatagcgcca
     9721 ataacttttt ggtagctgtt gactttgatg gttgccgtta tggattggct tatatggatg
     9781 tgtccacagg tgaattttgc gtgacagatt tggcggactt tacgagtgtt cgtagcgaaa
     9841 tccaaaacct caaggcaaaa gaagtcttac taggttttga tttatctgaa gaagaacaga
     9901 cgattttggt caagcagatg aatttgctgc tttcttatga agaaacggtc tatgaagata
     9961 aatctttaat tgacggccaa ttgacaacgg tagaactgac agcggcagga aaactcttgc
    10021 aatacgttca caaaacacaa atgcgagaac tcagccactt gcaagcattg gttcactatg
    10081 agatcaagga ttatttgcag atgtcgtatg ccactaagtc aagtttagat ttggtagaaa
    10141 atgctaggac taataaaaaa catggaagtc tctattggct gttagatgaa accaagacag
    10201 ctatggggat gaggcttttg cgctcatgga ttgatcgacc tttggtttct aaagaagcta
    10261 ttttagagcg tcaagaaatt attcaagttt ttctgaatgc ttttattgag cgaaccgatt
    10321 taagcaatag tttaaaaggt gtttacgaca tcgaacgctt atctagtcgc gtgtcttttg
    10381 gtaaggcaaa tccgaaagat ttacttcaat tggggcatac cttagcccaa gtgccttata
    10441 tcaaagctat cttagagtct tttgacagtc cttgtgttga caaacttgtc aatgatattg
    10501 acagtttgcc tgagttggaa tacttgatta gaacagccat tgatccagat gcaccagcaa
    10561 ctattagtga aggcagtatt attcgtactg gttttgatga gcgcttggac cattatcgta
    10621 aagtgatgcg agaaggaaca ggttggattg cggatattga ggctaaagag cgtcaagcaa
    10681 gcggcattaa taacctaaaa attgattaca ataaaaaaga tggttattat tttcacgtta
    10741 cgaattcaaa tcttagctta gttcccgagc attttttcag aaaggcaact ttaaaaaatt
    10801 ctgagcgtta tggaacagca gaattggcta agattgaagg tcagatgtta gaggctaggg
    10861 aagagtcatc tagtttagaa tacgatattt ttatgtgtat tcgagctcaa gttgaaacct
    10921 atattaatcg tttacagaaa ctggctaaaa ttttggcaac ggtagatgtt ttgcaaagtt
    10981 tagcagtcgt tgctgaaacc aatcattata tccggccgca gttcaatgat aatcatgtga
    11041 ttacaattca agaaggtcgt cacgcggttg ttgaaaaggt tatgggagtg caggaataca
    11101 ttcccaatag tatctctttt gaccaacaga ccagtattca gctgattaca ggtccaaata
    11161 tgagtggtaa gtcgacttat atgagacagc tggccttaac ggttatcatg gcccagatgg
    11221 gttcatttgt ggctgctgac catgttgatt tacctttatt tgatgcgatt tttacgcgta
    11281 ttggggctgc tgatgatttg atttctgggc aatcaacctt tatggtggag atgatggaag
    11341 caaaccaagc aatcaaacgc gcaagtgaca actctcttat tctatttgat gaactgggac
    11401 gaggtacggc aacttatgat ggtatggctt tagcccaggc aattattgaa tatatccatg
    11461 atagagttgg tgctaagacc atatttgcaa cgcattatca tgaattgaca gacttgtcaa
    11521 ctaagttgac aagtctagtc aatgttcatg tagcaacgct tgaaaaagat ggcgatgtta
    11581 ccttccttca taagattgct gagggaccgg cggataaatc ttacggtatt catgtggcaa
    11641 aaatagcagg actgccaaaa tccctattaa agagagcaga cgaagttctg acccgtttag
    11701 aaacacagtc acgatctact gagataatat cagtcccttc acaagttgag tcaagcagcg
    11761 ctgttagaca ggggcaatta tccctttttg gtgatgaaga gaaagctcat gagattaggc
    11821 aagcactgga agctattgat gtcatgaaca tgaccccgct tcaagcaatg acaacccttt
    11881 acgaattgaa aaagttgtta tagtctttca gctgaaaatg aaaaagatgc tttctatatt
    11941 gaaggcatct ttttgttctg tcaaaaacgg tccgaggcct tcggctattt attaagtgtg
    12001 ttataatagt ccataagaat gcgaggaaat tatgacaaac attattggac ttggattggc
    12061 agtctttaca gggtattgac agtccttaag cattgttatg actgtgtttt tgaaaaaata
    12121 taggttttaa gtttccttag acttccctca aaagtccaca aaaaggtgaa caaaaaaaga
    12181 cctttacagg tcctttacac aatgagttca gcaggcaaga actagcgtgg tttaaatact
    12241 acgcttttta gtttgcccta tggcttatta tagcacgatt agtgtcattg aggaaaaaac
    12301 taccctctca accagtcttt aaagttccac cattggtctt ggatgctatc gctcaagcgt
    12361 tgatgccaag tttttttgga ttcttcttcg atagaacgct tgaataacac ctccgcatat
    12421 tgttgctctt cggcatctct ctctttttga agacgttcat tatgtgtttt tccatcctca
    12481 aatacaagtt gcccaaagta tagattcccg tcatccgcaa aagataaggt aactttgtct
    12541 ccttcagcaa gtggtttttc caattgaact gtgtagttgc ctcctccatc agcacgattg
    12601 ccacttactg tccatttcct tccttcgcag tttggattat cttgtttctc caaaatagag
    12661 caaggaattt cataagtttt gttttcggtt tttttaattt tattaccatt acttgaagtt
    12721 acaaaaccat aaacataccc atagggatct agattaacat taatggttgt atctcctgtt
    12781 ttaaatggtg ctacggttac tccaggtaag tgcgattgcc ctatagttgt aaacaaatcg
    12841 ccactttcat tagctctgac acttatagca catattgata ttaacaaagt taacatcata
    12901 actaatttct ttttcactat attctcctta aaattaaata tcgaactcca caataccagt
    12961 taatcagtca aaaaatccat tctacttttt gatattttat gtctaatttg acccgctaag
    13021 tcagatttgc aaacgatacc aagtgatttt cttctaatca ttatttttta gatggatatg
    13081 ttaattgtat tagagacgta ttaatcttaa accattgtca taagcgaaca ttatttttta
    13141 gcgccccgtc tctgtaaaat tccacaaact caagcaaggc tcttttctta gattcataat
    13201 accagctttg acttctgtta agttcttcca taatgtcttg ttgagttttt tcctcactga
    13261 tcaagtaaca ctcaattagt atttgtctat attctacttt agacagttga ttaatggcat
    13321 acctaatagc gtctagttcc tctagggcgc attctcggct tatttcaagg tgttttctgc
    13381 gcgtgggatg gtactctata tcaaactggt aaagctcggt ataagttaaa tcaaggctat
    13441 tagcgatacg ttgccatcta tgaaattctt tcagcttacg aatagcgttc ttcttgctca
    13501 tctaacacct ctaaagcttc tctatgtagt ttgaacacaa tgtttcttga gtaacctagt
    13561 ttatcgagta tctcgtccca tgataagtca tccacgtatc tagccttaat aacagctatc
    13621 tgtctctcat cttggagcgt ggcgatcatg gctagtctct tatcacgttc tttagctaaa
    13681 tataagagtt gtttagctgt acctttttcg atatgtctta ttgcttcagg attatgaaaa
    13741 gcatttatca gctcgatgtc tttatctcgt tgttcctcaa ataaggttat taaagcgaaa
    13801 agtggtttca attctttaag ttgttcttta gcgctcatgg tcttttctcc tggttatggt
    13861 ataatttatt taagcttaaa tttaaccaag ggggcgttcg tgtggacgtc tttttgtttt
    13921 gttcgttttg taaactagat attttttgta gtacttcgct tttcgcttct aaaatcgttt
    13981 ctaagcgctt ttcagagctt ataatataaa atcatcaact tagcagacag aagcgctaaa
    14041 accatgtttt attttagtct tagatggtta ttctttgtgg cagggttatg ggctaaaatg
    14101 agatgtcaaa tcctttccta tcaagctttt taatcttcgt caaaaatttc aaaaagggaa
    14161 ttttttgcac ggaaaagggc gcgttcttaa gtttccgaac aatatagtcc cgtttaaaaa
    14221 tgaagggggt agtttccgaa tattatagcc agtacctgtc acccttatcc atatagtaat
    14281 gaaatcttct ccagtgataa aggtatttgg ttaatctcat gtactttgga cgtttaggaa
    14341 agtcatcacg actataatat ccatgaatgt gtcttgcttc tggatttact ttcaaacact
    14401 ctttaaaggc taattgccag tagtagcaac agtctgtctt gcttcgattg agcgtggctt
    14461 gatgaacctt ctgacaagaa ccacaagcaa aggcatgaga agccttaaat aatttccgac
    14521 aacgtctctc acagtcagga cacacgaaaa agtaacgttt accaccataa gttcctggaa
    14581 tcgtttcaag caataggcct tgaccattgt agtgaatcac tagcccatct aggtctatgc
    14641 ggatagcttg gtcacctatt gatcctgtaa ctcttgtctt cccctgtgtc ttcattggtt
    14701 taatgatatt ctcaatagat agttctaaca ttatttctcc ttaaaactca aacaacccaa
    14761 aactattgat aaaacgacaa aaagaggaaa aaccctctga atgtctattt aacgagtaac
    14821 tgaccttcaa caaccatatc atacaaatgg ttaaaggctt gactgataga ctcaaggatg
    14881 gcccctaagt cttctggcgt catctcttta taattcatag agaggtgttc agccagttgg
    14941 ttgtgatcgg agatgaaggc tataagtgtg tctcgattat taactttccc ttgagtactt
    15001 ttagataaag aaaccacgcg ctgatgatca agttcttcat ccgtcatatc ctcaggttgg
    15061 ttgtaatagt ccttgaagct gtcacagata cgcttgaaga ctttgtttag ttttctgtct
    15121 tcaacatatt ttaagactaa ctgattagca tgaccacctt ggtcatcatt gtgataagtt
    15181 gcgtcaatca ctggttgctc ataagtacca gtcatatagc ctaaaatagc atgacaagcc
    15241 acttgtgcgg tgtcaaagtc tttaaacgtg tagtggaatg tgaatgtctt tggtgtgtct
    15301 gaaaatgttc tcatgctatt tctcctttgt gattgctata atgtctgata aattgataat
    15361 ggcagaagga gatgctaccc agtttggttg ttctccagat aaaagatact tgaccaactc
    15421 attataaagg gtgcggtctc cttgtatggt gatggtgtta ccacctcgtg tgtgtaattt
    15481 tagtttcata tcagttacct gtacaagacc agtagtcctg ttcttgaatc catgtcttca
    15541 taattgccat aagtggcttc ttggaattta atgtctatca cagataccga tagggtaaag
    15601 agattgaccc gatgttcaaa atcatctagt gattcattgt gtttttgata aaatagtttg
    15661 attttcatgt tttagctcct ttctcaacag gtatcgcaaa gccacagtca aagacccatt
    15721 ggtaaccacg tcgtgttagt tctggtctgg taaaatcaca atcacccggt ctagacttta
    15781 tgttgaaatt aattttggtg ataaagtcat aaccgcattg accattagga agttccaatc
    15841 ggtatagctg gtcgtttggc aaatcatcat aattgtaacg cattttcttt acgccatgat
    15901 ttgtatagtt aggattcata tgtccctctt ttctctctaa aatgtgtgct ttttgttttt
    15961 ttaaaaatca aatagcacag caaaaagcac agggataaag ccagtggtat caagggggtt
    16021 gggcactttg tgcttttagt agcattaatt tgagcaaaag actttctttt tttgcacgcg
    16081 cactattagt tataaatatt attatctata atattaaata ctactaatac tacaatagag
    16141 tataaagcct ataataccaa ggttttagct tgtatcatta cgtgtagttt ttatgtagca
    16201 ttagtgtagt ttttaaactc gttcatagta aggtacggga gttccacctt taaatagtct
    16261 ttttcttgcg ggattctctc cttttttcca gccgtcatca ttatctaagt aatcacgtat
    16321 tttttgagaa ataagggcct taccaccttg cgttggtttt tggttaaatc ctagataagc
    16381 gatatggtta ggacttgtca cttggagtaa gcaatctgtc tgtgcggaag ggtagtcact
    16441 atagctttga gcattatcta acggctctcc tagctgtttg aggatgtatt gccgttgttc
    16501 atactgtgat aagctatccc aaccttcaac aatttgaaac tcattcagta attgatcgat
    16561 aatttctttg tcgacgtctt caaccttata atcttcttga atgtctgcta actgattcat
    16621 taactcttta gatggcgtta gtggttcata attgttaaac catactttgg cttcagcgag
    16681 tacctgtaag aaataatctt cttccacctc cataggatgt tttttcacgt cattgatacc
    16741 acattcaata gggaaaaagc gtctttctgt tccactatcc ttaagaaaag attttttatt
    16801 agctgttccg ataaagacac agtgccttgg atgaggagtg gctttacgtt cataaggttc
    16861 acgataagta tcactatctg aggaaatgaa gcttttaact gtttcaattt ctgcctttga
    16921 catgcctttt agctccccta gctcaataat ggcattggct tgtatcttct gataatcact
    16981 atcattttta ccaaacttga tttctgaatc agtgtggtag ctagggagta gtcgcttagt
    17041 aacggtgctt ttcccagttc cttgtctttt atcaatgaga ataggaacga cttcaaactt
    17101 tactttacgg agataaattc tagccatgag acctgttagc catactttgg caatttctct
    17161 attataggaa ttatcagcac agcctaatag atcaataaag tagcgttctc ctctagcttt
    17221 accatcccat ttttgacttt caatacgctg tttaatgggg tgataagtgt tctttttagc
    17281 taaagcggta atagctacct ctatatgttc tttacgaggg gtaaaccgat atttttcatc
    17341 aatgaatgca atacaaaggc tggtctgctc gttcgtccat agcccttttt ctttagacca
    17401 aggaactgct ttagtgattt caatagtttt ttcaaattcg ttgtatttaa tacctgtata
    17461 gatattttcg taaaattcaa aaaccttacc gacattgtag gggctactaa tgacatattc
    17521 tttgtctcct ctaccttttc gtgtcctgaa agcaggggca aaagcaggtt gagtggcttg
    17581 cgatagttta ttttgatagt ctttcaattc ttctttgtct atggcttgat tcctctcttt
    17641 cttaattctt tatcaagtat gcttctaaag gttgtatcta tctcatcaat gggtagtggc
    17701 ttagttgtca cgctgttagc tatttgtacc agctcataag ccgtctctaa atcacaatcc
    17761 acccatttat taaatagcaa gccaacaaac ttagttaagg ccacgttgcg cccgccttcg
    17821 tctccaaaac cattaaacaa ggtatctatg accctcatgg taatagaacg ctgacttcta
    17881 gggcgtggcg tgtaagtagt aacaacttgt ctgtttggcg tgctaccatt tttaggaaca
    17941 ggataatcaa gaccatggtt cacatagcgc tgatagtcct ctgggtcgcc tgttgtaacg
    18001 ggtaagcctt gtaattgcga ccaggtaaga ctagctaaat caaacggcag tccaatctta
    18061 tcggctatct ccttgaccac ttgtttataa gttgcttcag tcatcacgtc actaggcttc
    18121 atgacaaggc gataacgggg cttctcgggg gtgtgtttaa tcgttggata aataatataa
    18181 ctatactccc aaagcgtctg agaaacgatt ttaggtaggt tgacgcctgt ttctatctcg
    18241 tcatagtcaa gaaaaatcaa atcgcgataa actaaactag cattattgcg cttatagcta
    18301 ccgtttttct ctgctgtgac cttgccactt aggcagtagg gggcttgtgt tcgcttgtat
    18361 tcttcaatat caatatcctc aggcggtttc aaaggtctaa actgagcaac atagtcaaat
    18421 ggttctaaag gtcctttgta ggggtacaaa taagagctaa agcctcttgc ttcataaata
    18481 gccatctaca catttacccc caaaaagata agaatatcac tgaccttgta ataatgtttc
    18541 ctggtgtctt ctagtggtgg ttggtatcgt cttaacccag cattttccca ccgttttagg
    18601 gttttacctt tgatatttaa ttcctctttg acttgttcgg ccgtgatcaa ccctaaaact
    18661 cttggtttag gtttctggta ggcttccaaa aagtgattaa aagcggtcag gttttgttct
    18721 aagagtttgg cttcataatc ttgactaaat acgttcatgc ctaacctcct ttgagtaatt
    18781 ccttataact ggttaaatcg gcattcaata acacacttag gcgttcctgt tccttttgta
    18841 cttgattata aaaggcttta gcaccatcta gtaattcttc tttgttagct gggataaagt
    18901 acccacgatt gaatccgtgt ctaatgccga taatagggac gttatagcgc gtgattaagc
    18961 tactgatgat actttggacg gagcgttctt caagtttcag tattaagcta atctctgccc
    19021 ctgtaatggg gttgtctgct ccaaccttga tcagattaag gacacgtcta taattctctg
    19081 gtagtgtcat tcagttcctc cctaattgta ataatggttc tgtgcttgaa tataagcccc
    19141 atagtttgcg ttctgacgtg gtttaggtgc gtgggtatct tctggtaagt caatctctat
    19201 taacggctta gaacggctaa gaagaagccc taagagacct aaaacaaaga atagaataag
    19261 cgtctgtgtt ggtgtgaggt taagttcttg catcatgccg atacctcact taaataagtt
    19321 tctagttccc ctgagtcttt ctctgaacaa ggtaaaccgt taacggctct aaagacaatc
    19381 tctgtggttc gttgatagtc taaagcgtcc catgcttctt caaagctggt ggcacttttt
    19441 ctgaatttaa tgacgtactc tgtcataacg ttagcaataa ttacccaagc aatatgttgg
    19501 ttatatagtc gagtgaaata gacttcagct ttatctttgc tgagttggcg atttttgaac
    19561 atttctagct gttcaggagt gtatctatct tttgaaaaag gatttgtttc tactctatat
    19621 ttcattatgt cttttctcgc ttaattatta ttttctgtgt agtgttttta ttgattgctt
    19681 gtttcttata ctagattcat gctagtttta aggggtagct ccctgattag ttcatgttag
    19741 tgtataattc tgcgaataac tcgctaggga tacgctctag cgctttttgt tgtaagtgga
    19801 tggctttaat tctatcttgt gttttggttt taatgtcttc tataatttca gatgttgaga
    19861 ccacttgttc atagtaaatg ttagctttat aaatgagtcc ttgttctttt aattccttat
    19921 tagccatttt ttcaagcgta acttcatgta atacttcaac attacgataa tgaccgtttt
    19981 tgaggtcgaa ttttagccat tttttacgct tccatttata tagggtgctt ctgcaaactt
    20041 ctgaattccc aaaaccaaga aaagaagcga tttctgttaa tgtttttcct tcaatttcag
    20101 atagtttata agcgacgttt ctaaataaca ctctcggatt tctttttttc ttaatcatat
    20161 tgtcttgatt tttgagcaca caaaaagcgc actccctttc tatgaatttt aggttcacaa
    20221 aatagagtac gcatgatata ctatttacgt acctactttg tgggtgctgg gagttcctaa
    20281 cgtgtacggt cgccaaacta taccacgtta ggaacttttt tatttttcag actcataaga
    20341 gtttacagct ttaacgatta aatccgcttt agataatcca tttttatccg ctgtttcttg
    20401 tattgtatta tactcgtcag cggtcaaacg aacttccagc cgtttatcac gtttagctgt
    20461 accttttaca ggtctgccca tttttggact cataggagtt cctcctttca tttaagcccg
    20521 tgcttatatc atatgataag cacgtacata agtcaacccc taaattaaaa aaacatgcgt
    20581 attctatttt caatgtgcaa atggttcaca aaatagagta cgcatgatat actatttacg
    20641 tacctacttt gtgggtgctg gctctatcac gttgacggtt tggcgattgt aaacgtggta
    20701 gagtactttt ttattttgta agattttcaa aggcttttct caaagtctcg ggtttagtca
    20761 agttattctc tttagcgtac ttatttagtt tgctatctaa ctcttcacta acccttaccg
    20821 ttaatttaac agtatttgag ttttctccct ttggtcgtcc tactcgtttt ttggtgtcgg
    20881 tcattgagtt tatcactcct ttcatgtcga caaaaactat tatagtttat gtcgtcaata
    20941 attgtcaacc cctaaaccaa actttttttg cgtactctat tttattttca atgatcagta
    21001 tgatacaatg gaagtatcaa atatttacta aaaccccttt aataatagct tgcctgcttt
    21061 attaattgag tttagttata ctagttgaag gcttggaagt ttggtcgctg tcaaagcctt
    21121 ttttgttgtt ttcacgcgca ttgtagcgtg ttttttaatg ccattgtctt aatatcttga
    21181 taggtaaaat taagattgat aagagcgatt gccatatctt ctaaagcagt gtactgtgct
    21241 agttcaattg agtttaagca gtcaatatca gaataaccac ctctggttac ttttaattgc
    21301 ttgctattct taccagtaac agctttaagc aatagattgt acacagtcgg ataagccatt
    21361 ttaggcgcgt gttcccatgt cttgatagct tcattaagtg tttttcgttt aggagcttca
    21421 agagaacgct gtaacctaat ttgagtgagt tcttctcgca tttcaaagaa tgccttgact
    21481 aggttctttt taaactctct gactggttcg gtatttccta gataggtaac taataaagtc
    21541 gcctgctgtt cgtttaagtg ataaattctt ctaggtcgtc cgcctagtga acctttttca
    21601 ggtttatgga tttcaaatga caaaacccca aacgcttcta aaaggtaacg catggtcacg
    21661 caaagttacg cagaattttc catgttgcgt aacctactca atctctttag taccaatcga
    21721 tttcagcatt tatttaagaa aggttacgca gtaacaaaca ataagtctaa ttaatgattt
    21781 attaattatt tatttatata taggggtagg gtagggtgat tttgcgttac tgcgtaacca
    21841 tccttctcta acgctatcta tatcaacgtt ttagaggtta cgtagtaaaa aagggggtgc
    21901 gttaccttat gtaccacaca acagcacttt cgttcttaat cctttttatg cttatcaatc
    21961 agctttctaa ctgaaataat gtcaatttca gcatgttcag ctatgatgtc gtgtgtggtg
    22021 taaggctctt tcttaccatc catgtaaact aggttcatgg taatcctcct ttatccatag
    22081 agttccgtta gttctttaaa atactgatca ggaatttcat ccatagccac ttgttgtaat
    22141 tgaatggcct ttaaacgatt ggtgtcgcta gcagtcggtt tattaataat ttcagccgtt
    22201 gcctgtactt gcttgaaata ctcttcaagc ttaagttgcc ttcctgcgga aacttcttcg
    22261 gatatggctt ttctgttatt gataatttca aaggtatcaa tttcaccgtt tgccatggtg
    22321 taatcaatgt tatttcgata ccgccaagct gccagcctaa gcttgatgtc tttttcagac
    22381 caatcgggaa gccgctcagc aatcagctct aggctcattg ttcctgtatc gtcaaatatc
    22441 tgatgtaata attcttgtgt aaatggtgtt ctagccattt gttatttacc tgcctttctt
    22501 aatcggtgat agctaagaag tcgctaacag tttgattagc gagctgtgct attcttaata
    22561 gactgtttct attcgggagg tttcttcctt tctcccaatt attaacagta cctttagaag
    22621 tgccaaagcg ttttccgaat tcctccatag tttctcctaa gttaaggcga atagttttga
    22681 ttttgtcacc cactgtcatt tcttgcctgc ctttctaatt aataaagtac tattattttc
    22741 gtactttttt acctaaaaaa aggttatcaa tagtgacacc gtacaaagat gataattttt
    22801 gcaatagtcc taaagaaata tcggagctat ctttttcgta ctttgaaata gtttggggat
    22861 ttttcccaac cgctccagct acttgtttta aagtgtaacc agcgttgatt cgggcagctt
    22921 ttagtgtaat ttgcgtcatg ttttcaactc ctttctaaaa agctatggct taatagtact
    22981 attattttcg taccaagtca atgatttttg tagaaaaata ttaaaaaaat agtactttta
    23041 ggtttatttg tgttagaatt aattcagata caaaaagaaa ggggtaagag aaatggctaa
    23101 aaatagtccc caagatttaa taaatagaga aattttctca acaaatctca acatgcttat
    23161 ggctaaaaag aatatcaaac agatagatat tcacaacaaa ctaggaatac ctaagagtac
    23221 gataactggc tatgttaaag gtcgttcact cccaactgct ggaaacgttc aaaagctggc
    23281 ggacttcttc ggagttctaa aatcagacat tgacccccgt tttgattcta ataatattga
    23341 aacaaatagt aatattatcc catcaaccct acaaaaagta acatctactt tatctcagct
    23401 agaacacaag cgacaattaa acgtccttga ttatgctgaa acacaattag aacaacaaaa
    23461 cacagtagaa gaaccacaag ccacctacta cacttacaac tactacgacc acgcagcttc
    23521 agctggtaca ggtcagtatc taaatgatgt acaagtagaa acaattgaat taccagtcga
    23581 ttacgacgct gattttgtca taccggttta tggcgattct atggaacccg aataccattc
    23641 tggggactat gtatttatca aactatctat taacctgtca gatggtgata taggagtttt
    23701 tgagtattac ggtgatgctt atatcaaaca acttgttata aacgattctg gagcgtttct
    23761 gcatagtctg aacgacaagt atgacgatat actcatagat agagatagtg atttccgtat
    23821 tatcggagaa gttattggga gttttacatc taaatcatga ctatctgata cccacgcgcc
    23881 gaattccact attttccact aattttggtt gctttacctt taaggactcg cattttgctc
    23941 tttaagacag ccgaaaagtc cgattttctg aatactatac gctaaaaatg ccaactgatt
    24001 ttagaagctg tcacaacgga aaaagtaaat taataaacga ccgatatatc aagttcttta
    24061 agtgaattta ccgagcgttt tacaactatt gaaataggtt gacgtattat gtcagtacgt
    24121 gccaacattt tccagcattc cgaaatgcga ccatgtgttc gtgtttggga gtagtaacct
    24181 tctattctct aagttcgctc gaagttcagc attatgcgcg tggaataaaa ttagctacct
    24241 tactgtaacc ttaccgttac cgctcatttt atgacctgtt caattttcat gtctaaatgc
    24301 caaatttatc atctttacct acgcgcaaat accttgatac gcctttaatt ttctttaatt
    24361 acaagaccct caaaacttgg caaaaattga ggtataatct gaacttttct gaactttttg
    24421 tcggcggtaa ttaaaaaaac tatctgcgcg tgatcagtgg ttgcataaag tattataaat
    24481 tcttgcataa aattattttt attcattttg gtaatactaa ggaatgttaa gagcgctaaa
    24541 gactgtactt tctaactaca cccttttgac ttctttatca aacaaagcta taatggacat
    24601 agaaaaagga gattgcgcaa acaatctcct gtggtagcac cgtttaagac ggcagcctta
    24661 ccgtatttgt ttatattttc tataaaccgt ccacgattgg ctaaagtgtg ggacggtttt
    24721 tctatttgtt cttgttattc atgatagcta ctatcagagt accaaaggca atcatcaaag
    24781 taagcgtttc ataaactgac aaaccttgtc gtctcctttc ttttggtttc tgtgacttac
    24841 atacataagc accacctcca gacataaggc tacgactacc ttgacctagt ttttagacat
    24901 gcaaaacttc ttctgaaact ctctgtacct tacaaaacca aacaaaaaag accacgcaag
    24961 ttttccacgc tcgcaaggtc ttaaaaagac taatattata ccatgatttt cttttataat
    25021 atttcggata tttacccgat accattatta taccatgata tgaactaatc taaaaccctt
    25081 ttaataatag cttgcctgct gatggaaagg tttatgatca tgaaaataac agaacataag
    25141 aagaaaaacg gtacaattgt ttatcgtgct agtatttatc taggcattga ccaaatgaca
    25201 ggtaagagag taaaaacaag catcacagga agaacaagaa aagaagttaa tcaaaaagcc
    25261 aagcacgcgc agtttgactt cctatctaat ggatctacaa ttaaaagaaa agttgtgatt
    25321 aaaacattta aagaacttag tcatttatgg cttgaaacct ataagttaac agtaaagcct
    25381 caaacttatg atgctactgt tactagactt aatcgacata ttatgccaac tctgggcaat
    25441 atgaaggttg ataagataac cgctagtgat attcaaatgc tgattaatag attatctaaa
    25501 tattacgtca attatactgc ggtacgttca gtcatccgaa aagttctcca acaaggagta
    25561 ttgctagggc taatagatta taactcagca agagatatta tccttccaag gaagcagcca
    25621 aacgctaaga aaaaagttaa gtttattgat ccgtctgatt tgaaatcttt tttagaacat
    25681 ttagaaacta gtcaacacaa acgctataac ctttactttg atgcagttct ctaccaactt
    25741 ttattatcca ctggcttgag gataggcgaa gcctgtgcat tagagtgggg agatattgac
    25801 ctagaaaatg gtacaatagc cattaataag acttacaata aaaatttgaa gtttttgagt
    25861 acagctaaaa cccagtcagg caatagagtg attagtgttg ataaaaagac ccttagaagc
    25921 ctaaagctct atcaaatgag acagcgacaa ttatttaatg aggttggtgc gcgtgtgtcg
    25981 gaggtagtgt ttgccacacc aacacgaaag tattttaatg cttcggttag acaaagcgct
    26041 ttagatacta ggtgtaagga agcagggatt gaacgcttta cctttcacgc ttttagacac
    26101 actcacgcta gtttattgct gaacgcaggt attagttata aggaacttca gtaccgtcta
    26161 ggacatgcga atatcagcat gactttggat acctatggcc atctttctaa ggacaaagaa
    26221 aaagaagctg ttttatatta tgaaaaggct atgaataatt tataagtcca caaaaaagtc
    26281 cacaaattaa tattttgaga ggtgtaaacc taatgaaacc ttgttatatc aacgtttaga
    26341 aagtgttaaa aac
//
LOCUS       DATWEK010000023        25853 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.023, whole genome shotgun sequence.
ACCESSION   DATWEK010000023 DATWEK010000000
VERSION     DATWEK010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25853
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.023"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            106..1518
                     /locus_tag="VCR92_001186"
     CDS             106..1518
                     /locus_tag="VCR92_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEP4268257.1"
                     /translation="MVKSSDSCTTILVGKKASYDGSTMVARTEDSQNGDFTPKKMIVV
                     KPEDQPRHYRSVQSSFEMDLPDNPMTYTSVPDALGKDGIWAEAGVNEANVAMSATETI
                     TTNSRVLGADPLVASGIGEEDMVTLVLPYIRSAREGVLRLGAILEDYGTYESNGVAFS
                     DEHDIWWLETIGGHHWIARRVPDDAYVTNPNQFGIDYFEFNNPEDYLCSADLKDFIDT
                     YHLDLTYNHEHFNPRYAFGSQRDKDRHYNTPRAWIMQKFLNPEIVQDPRSFALAWCQK
                     PYRKITVEDVKYVLSSHYQDTVYDPYGSEGTPVSKKVFRPIGINRTSQTAILHIRPNK
                     PQEIAAIQWMAYGSMPFNTMVPFFTQVKTIPDYFANTYENVSTDNFYWTNRLIAALAD
                     PHYNHHETDLDNYLEETMAKGHAMLHAVEAQLLAGETVDLEEENQKMSDYVQGETQTL
                     LNKILFDASNLMTNRFSLSD"
     gene            1670..3217
                     /locus_tag="VCR92_001187"
     CDS             1670..3217
                     /locus_tag="VCR92_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEP4268258.1"
                     /translation="MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEF
                     TKGVIGNDGDVSMLMKAGTEPHDFEPSTKDIKKIQDADVFVYMDDNMETWVSDVKKSL
                     TSKKVTIVKGTGNMLLVAGVGHDHHHEEADKKHEHNKHSEEGHNHAFDPHVWLSPYRS
                     ITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAA
                     FGYMALDYGLNQISINGVTPDAEPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTL
                     AKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTK
                     TVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQDGTLDQVWDYKAKKSKGKMTAAEYKD
                     YYTTGYKTDVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEA
                     KEPNAGEFKYVQFSDHAIAPEKAEHFHLYWGGDSQEKLHKELEHWPTYYGSDLSGREI
                     AQEINAH"
     gene            3365..4087
                     /locus_tag="VCR92_001188"
     CDS             3365..4087
                     /locus_tag="VCR92_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP4268259.1"
                     /translation="MPKEQPLYLQIVDDLEVKIKKSMTENDKLLSERELSDLYGVSRI
                     TIRLALKELELRDLIYKKQGKGTYVSGIKEPVTDLSSTYSFTEQMKKVGKTPKTEILS
                     FEQYQVTPYLSGLLEFDLDTEVFELERLRIADDMPLMFERSYIPAQPFQGLSIADLKR
                     KALYDIFAKDYQETIRLAEEEFYASIALDYEADLLGIKKGDPVLHIIRKTYNDKNILI
                     EFTFSIARADQFRYRVQHHPNG"
     gene            4107..5306
                     /locus_tag="VCR92_001189"
     CDS             4107..5306
                     /locus_tag="VCR92_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEP4268260.1"
                     /translation="MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFEETRDSLDS
                     FLKRVCKSANGNNVHVIFTGAGTSEYIGNTICPYLKKVGNRQCYLFESVASTDLVAAP
                     DYYLAEEETVLLVSFARSGNSPESVAAVNLVNQLVPNSYHLTITCAKDGELAKKAQQD
                     ERSYLYLMPEDANDAGFAMTGSFTCMMLAALLIFDDANSIAQKEAYVTDMILAGQAVI
                     DQERRLQELADLGFERLVYLGSAGLAKLTQEAQLKMLELTAGQVATLYESSMGFRHGP
                     KSFINDRTLVIGFVNNDAYVRQYDLDMLEEIQADGIALKILALLQGGDINFSEDQFRL
                     DTRHLLPEAYLAFPMILVAQTLALLTAVTLGNSPDTPSATGTVNRVVKGVTIHPYPTS
                     SRQCNKA"
     gene            complement(5403..5663)
                     /locus_tag="VCR92_001190"
     CDS             complement(5403..5663)
                     /locus_tag="VCR92_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEP4268261.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYQFLSGSTKASKETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(5778..6719)
                     /locus_tag="VCR92_001191"
     CDS             complement(5778..6719)
                     /locus_tag="VCR92_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEP4268262.1"
                     /translation="MITTFETILDKIKAHQTIIIHRHQNPDPDALGSQAGLKEIIAQN
                     FPDKKVLMTGFDEPSLTWISQMDQVTDKDYKEALVIITDTANRPRIDDERYTLGQCLI
                     KIDHHPNDDVYGDFYYVDTSASSASEIIADFAFSQNLTLSDKAAKLLYTGIVGDTGRF
                     LYASTTSKTLSIASQLRHFEFDFAAISRQMDSFPLKIAKLQSYVFEHLTIDESGAAYV
                     LVSQETLKHFDVTLAESSAIVCAPGKIDNVQAWAIFVELTDGNYRVRMRSKEKIINGI
                     AKRHGGGGHPLASGANSANLEENQAIFRELIAVCQEI"
     gene            7113..7562
                     /locus_tag="VCR92_001192"
     CDS             7113..7562
                     /locus_tag="VCR92_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEP4268263.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVDIDECTTVDAS
                     EFENADIAVVATYTYGDGDLPDEIVDFYEDLQDLDLEGKIYGVVGSGDTFYDYFCKSV
                     DDFSDQFALTGAVKGAEPVKVDLAAEDEDIDRLEAFAEQLSQAVNNL"
     gene            7737..8021
                     /locus_tag="VCR92_001193"
     CDS             7737..8021
                     /locus_tag="VCR92_001193"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEP4268264.1"
                     /translation="MRLEEIRQEINGIDHHLVALLEKRMALVEQVTAYKLANHLPVLD
                     QARENQILDRVSYLVKDQAFEPAIHETFKTIMSLSRQYQTQRLTGGDIND"
     gene            8014..9276
                     /locus_tag="VCR92_001194"
     CDS             8014..9276
                     /locus_tag="VCR92_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HEP4268265.1"
                     /translation="MIKSIATLPKPSLKEALGLIGLALPIGATVGVVDVIFGKGLLFL
                     SEYRDHHLFLLLPFLALAGLVIVFLYDKLGKEVRQGMGLVFQVGHGQKDQIPPILIPL
                     ILFSTWVTHLFGASAGREGVAVQIGATISHYCQRFVTSQEAARHLLIMGMAAGFAGLF
                     QTPIAAVVFALEVLLVGTLRYCALLPSLVAACVASWTSHSLGLEKFTIVLEETLTITP
                     LTLVKLIGLGLIFGLVGNSFAYLLGWFKPYLSQKLPNPYFRIAFIGALLSICLMIGHV
                     GRYSGLGTHLIAAAFSGQTILTYDWLLKMIVTVISLSAGFQGGEVTPLFAIGASLGIV
                     LAPYLGLPVLLVAALGYTTVFGSATNTFWAPIFIGIEVFGPENALAYFVTSAAAYMVS
                     HRHSIYSYQKVVMINLKDMTVNQMDLKK"
     gene            9391..9738
                     /gene="rplS"
                     /locus_tag="VCR92_001195"
     CDS             9391..9738
                     /gene="rplS"
                     /locus_tag="VCR92_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEP4268266.1"
                     /translation="MNPLIQSLTEGQLRSDIPNFRPGDTVRVHAKVVEGTRERIQIFE
                     GVVISRKGQGISEMYTVRKISGGIGVERTFPIHTPRVDKIEVIRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            9985..10056
                     /locus_tag="VCR92_001196"
     tRNA            9985..10056
                     /locus_tag="VCR92_001196"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10018..10020,aa:Arg,seq:cct)
     gene            complement(10099..10356)
                     /locus_tag="VCR92_001197"
                     /pseudo
     CDS             complement(10099..10356)
                     /locus_tag="VCR92_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017770118.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            10752..11321
                     /locus_tag="VCR92_001198"
     CDS             10752..11321
                     /locus_tag="VCR92_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HEP4268267.1"
                     /translation="MKGMNYQDYIWDLGGTLLDNYELSTQAFVQTLAFFSLPGDHDAV
                     YQKLKESTAIAVAMFAPNEPEFLHVYRLREADKLAQPIWCLGAKEILEKIATSGSRNF
                     LISHRDCQVNQLLEQAGLLIYFTEVVTASNGFARKPNPESLFYLKEKYDINSGLVIGD
                     RLIDKQAGQAAGFNTLLVDGRKNLLEIVT"
     gene            11322..13274
                     /gene="gyrB"
                     /locus_tag="VCR92_001199"
     CDS             11322..13274
                     /gene="gyrB"
                     /locus_tag="VCR92_001199"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEP4268268.1"
                     /translation="MIEENKHFEKKMQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIKVFIEADNSITVVDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGQIHYQEFKRGAVV
                     ADLEVIGTTDVTGTTVHFTPDPEIFTETTQFDYNVLAKRIQELAFLNRGLKISITDKR
                     SGMEQEEHFHYEGGIGSYVEFLNDKKDVIFETPIYTDGELEGIAVEVAMQYTTSYQET
                     VMSFANNIHTHEGGTHEQGFRAALTRVINDYAKKNKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDANQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGADFDVSKARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGIDQEDQ
                     LKTALEKYSIGRSKPTVQRYKGLGEMDDHQLWETTMDPENRLMARVTVDDAAEADKVF
                     DMLMGDRVEPRRNFIEENAVYSTLDI"
     gene            13642..15366
                     /gene="ezrA"
                     /locus_tag="VCR92_001200"
     CDS             13642..15366
                     /gene="ezrA"
                     /locus_tag="VCR92_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEP4268269.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDSLITSLEERKQAL
                     FALPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTVNSFADIENHIFEAENLNDTFN
                     FIRAKHEINSVESQLNLVEEDIASIREALNILKEQEEKNSARVTHALDLYEKLQASIS
                     ENEDNFGSTMPEIDKQMKNIETEFSQFVALNSSGDPVEASEVLDRAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRAREENTHIQERIDSLYEVFEREIAAYKVAAKNSKMLPRYLAHVKRNNEQLKD
                     EIARLSRKYILSETESLTVKAFEKDIKEIEDSTLAVAEQFGLQEKPFSELQVTFERSI
                     KTLTNVESGQMDVFAAVKDIEKIESQARHNLDVYVTQLHMIKRYMEKRHLPGIPQDFL
                     SAFFTTSSQLEALMDELSRGRINIEAVSRLSEVATVAIANLEDLTYQVVQNATLTEQL
                     LQYSNRYRSFEAGVQSSFEHALRLFEVENDYQASFDEISYALETVEPGVTDRFVNSYE
                     KTREHIRF"
     gene            complement(15498..15956)
                     /locus_tag="VCR92_001201"
     CDS             complement(15498..15956)
                     /locus_tag="VCR92_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEP4268270.1"
                     /translation="MTNLEDKLLKGAWGERRLNPEQQRYYLGTYAERVVLSALLDEAQ
                     TKTVKDYLKRELPSLQLVYQPLHLKISSKLAPQLQILYMKLAKENHLPVTIITETHMT
                     SPFAFILHTDHAINLKETRLEVILKQTKNDQLSKQPPEKTKSFWKRFLKK"
     gene            16183..17490
                     /gene="eno"
                     /locus_tag="VCR92_001202"
     CDS             16183..17490
                     /gene="eno"
                     /locus_tag="VCR92_001202"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEP4268271.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQV
                     DYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIK
                     ENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(17972..19000)
                     /locus_tag="VCR92_001203"
                     /pseudo
     CDS             complement(17972..19000)
                     /locus_tag="VCR92_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677767.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(19280..20821)
                     /locus_tag="VCR92_001204"
     CDS             complement(19280..20821)
                     /locus_tag="VCR92_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP4268272.1"
                     /translation="MLHLHLETKLQDKLSLLNILLDVSEVSIDQLCQETELKKQRVYN
                     LLFEMIKDLEDTLTLTICDDTVSIPYKTYQLKMPYFKKLYQTSIFLKMLCFLIEPGEL
                     SLHDFIKREYISQATAYRIRTNCRKYLKKVGLNVRQNHIVGPEYRIRFLIALLHYQFG
                     MTIYDFDKTSMNKVVSLIINSNQAITLNDASKAPYEFSYFAILISLIWKRRHDNLGIP
                     QTDAFKHLKKLSIYRDIKMTSQEIIGKWYHPDLTDEDLDYIFLCFCTTNNSFHKDKWT
                     PKKVKELFELVMTKTNGKTLKASLRPLLGNNILNSLPFKRILVSFSRLFISNLQVLLP
                     DIHLFHYLRRQQKRNKSFYNTLKTIVEEWMSAEGIVGKLPSYHLLLFTIQLEELLKTY
                     LPPIPVYLLTNNTAALDLMTNALSIYFPPAIATVMPVNVEIIPFKDIVKEKQSVIIAD
                     RQYLNLIQHLYQNQGHLFLYFLFSFRDVSEAYIHKAFLDFRQKRYDEFIVTLLDTYHK
                     NLSSP"
     gene            22177..>25853
                     /locus_tag="VCR92_001205"
     CDS             22177..>25853
                     /locus_tag="VCR92_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEP4268273.1"
                     /translation="MLKKIEVKEGQKNPISITLSEDQAKSLKNKEKLKVSIKQKQSKK
                     TSKDFFFEVGIDPKVKAKQQEKLLELDKVKKQIEDSINGDAWLPEKSEGEKPVQNTNK
                     ELQLQELNKKYQMAKEAIESATTLDDVETQFDKYTKVGDKDKYPDSLRNQYTRGDKDK
                     EIEKAKKSLGDLSDKVNGKIEEDKWLSDEVKKKQQQELEARKQKVNDSLKGSDSLKSL
                     RETVEKASSKNQKKPESFEDVYVPGNEETEKTKVRDILQKTYQKTEQNIETDPWLSPE
                     QKKAQKENAKARLDAGLKAVETTESLDKLKEVESDFLDKEKNPDSIPNQHKAGTPEVA
                     RKTFLDNFEKEAKKEIESIDKDDTLTANAKQVAKDKVAQQLQEATAKVEKAQSFDDLK
                     NIQDKFNSELPHTPGKPLKDQQSDAIAELEKKQQEIEKAIEGDKTLPRDEKEKQIADS
                     KERLKSDTQKVKDAKNADAIKKAFEEGKVDIPQAHIPGDLNKDKEKLLAELKQKADDT
                     EKAIDSDKTLTAKEKEEQKAKTKEELQKATEAVGAIDNREELDKKVPELKKAIEDTHV
                     KGNLEGIKNKAIEDLKKAHTETVAKINGDDTLDKATKEAQVKEADKALAAGKEAITKA
                     DDADKVSTAVTEHTPKIKAAHKTGDLKKAQVDANTALDKAAEKEREEINNDITLTAKD
                     KEQQLKEVETALTKAKDNVKAAKTADAINDARDKGVATIDAVHKAGQDLGARKSGQVA
                     KLEEAAKATKDKISADPTLTSKEKEEQSKAVNAELKKAIEAVNAADTADKVDDALGKG
                     VTDIKNQHKTGDPIEARRGLHNKSIDEVAQATKDAITADTTLTEAEKETQRGNVDKEA
                     TKAKEELAKAKDADALDKAYGDGVTSIKNQHKSGKGLDVRKDEHKKALEAVAKRVTAE
                     IEADPTLTPEVREQQKAEVQKELELATDKIAEAKDADEADKAYGDGVTAIENAHVIGK
                     GIEARKDLAKKDLAEAAAKTKALIIEDKTLTDDQRKEQLLGVDTEYAKGIENIDAAKD
                     AAGVDKAYSDGVRDILAQYKEGQNLNDRRNAAKEFLLKEADKVTKLINDDPTLTHDQK
                     VDQINKVEQAKLDAIKSVDDAQTADAINDALGKGIENINNQYQHGDGVDVRKATAKDD
                     LEKEAAKVKALIAKDPTLTQADKDKQTAAVDAAKNTAIAAVDKATTADGVNQELGKGI
                     TAINKAYRPGEAVKARKEAAKA"
BASE COUNT         8442 a         4486 c         5384 g         7541 t
ORIGIN      
        1 tgaaattaca agcttaaaat aaaaggcggt cggttgaccg tcttttttac ttttgtaaac
       61 taaatttgtt ataatgatat ggatagtaaa caaggagaat atattatggt taaaagttct
      121 gattcatgca caactatact cgtcggtaaa aaggcatctt atgatggctc aaccatggtt
      181 gctcgaacag aagattctca aaatggtgat ttcacgccta aaaaaatgat tgtggtgaaa
      241 ccagaagatc aaccgagaca ttaccgttcg gtgcaatctt cctttgaaat ggacttaccg
      301 gacaatccca tgacttacac gtctgttccc gatgcgcttg gtaaagatgg tatctgggca
      361 gaagcaggcg tgaacgaggc taatgtggcc atgtcagcaa ctgaaaccat cactaccaat
      421 tctcgtgttt taggggcaga tcctctagta gcttctggta ttggtgagga ggacatggtg
      481 accttagtgc tcccttatat ccgttctgcg cgtgaagggg ttttgcgcct tggtgccatt
      541 ttagaagact atggcactta cgagtcaaat ggtgtggctt tttcagatga acatgacatt
      601 tggtggctgg aaacgattgg tggtcatcac tggattgcaa gacgggtgcc agatgatgct
      661 tatgtcacca atcccaatca atttggcatt gattattttg aatttaacaa tcctgaagat
      721 tacctttgct cagctgattt aaaggacttt attgacacgt atcacttaga tttaacctat
      781 aaccatgagc attttaatcc ccgttatgcc tttggtagtc aacgtgacaa agaccgtcac
      841 tataatacgc cacgtgcttg gatcatgcaa aaattcttaa acccagaaat tgtgcaagac
      901 ccgcgcagct ttgcccttgc ttggtgtcaa aaaccttacc gtaaaataac agtagaagat
      961 gtcaaatatg tattgagtag tcactatcag gacacggttt atgaccctta cggttcagaa
     1021 ggaactcctg ttagtaagaa agtctttcgc cctattggca ttaaccgtac cagccaaacc
     1081 gctatcttac acattcgtcc taataaacct caagaaattg cggctatcca gtggatggct
     1141 tatgggtcaa tgccatttaa taccatggtg ccttttttca cacaggtgaa gactattcca
     1201 gattattttg ccaacactta cgaaaatgtg tctaccgaca atttctattg gaccaaccgt
     1261 ctgattgcgg ctttggcaga tcctcactac aatcatcatg aaactgattt ggacaattac
     1321 ttggaagaaa ccatggcaaa aggtcatgcc atgttacatg ctgtggaagc acagttattg
     1381 gctggtgaaa cagtcgattt ggaagaggaa aatcaaaaaa tgagtgacta tgtgcaagga
     1441 gaaacgcaga cgctgttgaa caagattctc tttgacgcta gcaatctaat gaccaatcgt
     1501 ttcagtttga gcgattaaaa gtgaagctaa ggctgagcaa ctgcttagcc ttttttacga
     1561 taacttttta ggaaaagtaa tcgcaaaaag acaaaaactt ggaaaaaaaa tcaaagtatg
     1621 ctatacttaa ctggtcaatt tttaaccagt taataacaaa ggaggaatca tgaaaaagaa
     1681 aattctttta atgatgagtt taatcagtgt cttttttgct tggcaactta ctcaggcaaa
     1741 acaagtctta gcagagggta aagtgaaggt ggtgacaact ttctatcctg tttatgaatt
     1801 tacaaaaggg gttattggta atgatggcga tgtttccatg cttatgaaag caggaacgga
     1861 acctcatgat tttgagcctt ctacaaaaga cattaaaaaa atccaagatg cagatgtatt
     1921 tgtttatatg gatgacaata tggaaacttg ggtttctgat gtgaaaaaat cattgacatc
     1981 taaaaaagtg accatcgtca agggaactgg taacatgctc ttggtagcag gagttggaca
     2041 tgaccatcac catgaggaag ctgacaaaaa gcatgagcat aataaacata gcgaagaagg
     2101 acacaaccat gcttttgacc cacacgtgtg gttgtcacca taccgtagca ttacggtcgt
     2161 tgaaaatatt cgcgacagtc tttcaaaagc ttacccagaa aaagcagaga acttcaaagc
     2221 caatgccgct acttatattg aaaaattaaa agagcttgac aaagactata cggcagcact
     2281 ttcagatgct aagcaaaaga gctttgtgac acaacacgca gcttttggtt atatggcact
     2341 tgactatggc ttgaaccaaa tttctattaa tggtgtcaca ccagatgcag aaccatcagc
     2401 aaaacgtatt gctactttgt caaaatacgt taaaaaatat ggtatcaaat acatttattt
     2461 tgaggaaaat gcgtcaagta aagtcgcaaa aaccctagct aaagaagcag gagttaaagc
     2521 ggctgtgctt agtccgcttg aaggtttgac tgaaaaagag atgaaagctg gccaagatta
     2581 ctttacggtc atgcgtaaaa accttgaaac cttacgctta accactgatg tggctggtaa
     2641 agaaattctt ccagaaaaag acacgactaa gacagtttac aatggttatt tcaaagacaa
     2701 agaagtcaaa gatcgtcaat tatctgactg gtcaggtagc tggcaatctg tttaccccta
     2761 tctacaagat ggtactttag accaagtttg ggactataag gctaaaaaat ctaaaggtaa
     2821 aatgacagca gccgagtaca aagattacta cactactggt tataaaactg acgtggaaca
     2881 aatcaaaatc aatggtaaga aaaagaccat gacctttgtt cgtaatggtg aaaagaaaac
     2941 cttcacttac acatacgccg gcaaagaaat cttgacctat ccaaaaggaa atcgcggagt
     3001 tcgtttcatg tttgaagcta aagaaccaaa tgctggcgaa ttcaaatacg ttcaattcag
     3061 tgaccatgcc attgctcctg aaaaagcaga gcatttccac ctgtactggg gtggtgacag
     3121 ccaagaaaaa ttacataaag agttagaaca ttggccaact tactacggtt cagacttatc
     3181 tggtcgtgaa attgcccaag aaatcaatgc tcattaatct taactcacta agcaaatctt
     3241 cttttaagga ggtttgcttt ttctttgtgg agtaaaaaaa tttaataatt ctcaacatta
     3301 atttgacgga cacttatgat tataatatac tttaagtggt tataacaagt tagaggtgaa
     3361 taagatgcca aaagaacaac cactctatct acagattgtt gatgacttgg aagtgaaaat
     3421 caaaaagagc atgacagaaa acgataagtt gttgtcagaa cgagaattaa gtgaccttta
     3481 cggtgttagt cgtatcacga ttagactggc tcttaaggaa ttggaattac gagacttaat
     3541 ttataaaaag cagggcaagg ggacttatgt ttcaggaatc aaagaacctg tcactgattt
     3601 atcaagtact tacagcttta cagagcaaat gaaaaaagtg gggaaaactc ctaaaacaga
     3661 gattctttct tttgaacagt atcaggtaac accttacttg tccggtctct tagagtttga
     3721 tctcgataca gaagtttttg aattagaacg cctaaggatt gcagatgata tgcccttgat
     3781 gtttgaacga tcctatattc ctgcgcagcc ttttcagggg ttaagcattg cggacttgaa
     3841 gcgtaaagct ttgtacgata tctttgcaaa ggactatcaa gagacaatcc gtcttgcaga
     3901 agaagagttt tatgccagca ttgccttgga ctatgaagca gaccttttgg gaatcaaaaa
     3961 aggagatcct gtcttacata ttattcgtaa aacttataac gataaaaata ttttgatcga
     4021 atttactttc agtattgcaa gagcagacca gtttaggtat agggtacaac atcaccccaa
     4081 tggttaaaga aatgggaggt taatacatgt ttacaaaaac gcaggaagct ttggaggctc
     4141 ttggtgcagc tatcactacc aaggaaatta aacaagaacc ccgtttatgg caagaaacca
     4201 tgacgttttt tgaagaaaca agagattctc tggattcttt tttaaagaga gtttgtaaaa
     4261 gcgctaatgg aaataacgtt catgtcatct ttacaggtgc gggtacatct gagtacatcg
     4321 gtaataccat ttgcccttac ttgaagaagg tggggaatcg gcagtgctat ctctttgaga
     4381 gtgttgcttc aaccgatttg gttgcggcgc cagattatta tcttgctgag gaagagacgg
     4441 tactattagt ctcctttgct aggagtggta atagtccaga aagtgtagcg gctgttaacc
     4501 tggtcaatca actagtgcca aatagttatc atttaaccat tacgtgtgcc aaagatggag
     4561 aactggcgaa aaaagcacag caagatgagc gttcttacct ttatttgatg cctgaagacg
     4621 ctaatgatgc tggttttgcc atgactggta gttttacctg tatgatgcta gcggctcttt
     4681 tgatttttga tgatgctaac agtatagctc agaaagaagc ttatgtgact gatatgattc
     4741 ttgctgggca agctgttatt gaccaagaaa gacggctaca agagctagct gatttaggat
     4801 ttgaacgttt agtttatcta ggttctgctg gtttagccaa gttaacccaa gaagctcaat
     4861 taaaaatgtt agaattgaca gctggacaag ttgcgaccct ctacgagtcc tctatgggct
     4921 ttaggcatgg tccgaaatct tttattaatg accgtacctt agtcattgga tttgtcaata
     4981 atgatgctta cgtcagacag tacgatttgg acatgttaga ggaaatccaa gcagatggca
     5041 ttgcccttaa aatcttggct ctattgcaag gaggggatat caacttttca gaggaccaat
     5101 ttcgactaga cacccgtcac ttattgccag aagcttactt agcttttccc atgattttag
     5161 tcgcgcagac cttggccctc ttaacggccg ttacattagg aaattcccct gacaccccat
     5221 ctgcgacagg aacggttaat cgtgtggtca aaggagtaac gattcaccct tacccgacta
     5281 gtagtcgtca atgcaacaaa gcttaaagct tttgtgtaga agccgtaaaa cgaaatgatt
     5341 ttgtgctagt aggccaaaag aaaaaccctc ctgatacagg aaggtttttt gtattgtctt
     5401 gcttattttg ctgcgtttgc gtctttgaga ccgtattttt tgttgaagcg gtccacacgt
     5461 ccatctgctt gagtgaactt ttgacgtcct gtgtagaatg ggtgtgaatc tgatgaaatt
     5521 tccacacgga taagtgggta agtttcacct tcaaactcaa cagtttcttt agaagctttt
     5581 gttgagccgc taaggaactg gtaacctgta gttgtatcaa ggaaaacaac tggacgataa
     5641 tctggatgaa tgtcttttct catcttaaaa aattcctttc tgccatgaca cttgatgcat
     5701 catagttatt aactattcta gtgtaacaaa acttgaatga cttgacaagg cttttctttc
     5761 cttatttttt aaaaatccta aatctcttgg caaacagcga tgagttctcg gaaaatagct
     5821 tgattttctt ctaaattagc tgagttggct ccgctagcaa ggggatgccc ccctccaccg
     5881 tgacgcttag caatgccatt aataatcttt tctttactgc gcatacgcac acggtagttg
     5941 ccgtcagtta actcaacaaa aatagcccaa gcttgaacgt tatcaatttt accaggagca
     6001 cagacaatgg cagagctttc tgctagggtc acgtcaaaat gttttaaggt ttcttggctg
     6061 acaaggacat aagcagcccc actctcatca attgttaaat gctcaaagac gtagctttgc
     6121 agctttgcta ttttcaaagg aaacgaatcc atttgccttg aaatcgcagc aaagtcgaac
     6181 tcgaaatgtc tgagttggct agcaatggaa agggttttac tagtggttga ggcataaaga
     6241 aatcgccctg tatcaccaac gataccagtg tataagagct tagcagcctt gtcagagaga
     6301 gtaagattct gactaaaggc aaagtctgca atgatttcac ttgcgctaga agcgcttgtg
     6361 tccacataat agaagtcacc atatacatca tcgttgggat ggtgatcaat cttaattaag
     6421 cactgcccca gtgtgtagcg ctcatcatca atccttggtc gattcgctgt atctgtaatg
     6481 atgaccaaag cctctttata gtctttatca gtcacctgat ccatttggct aatccaagtt
     6541 aaactaggct catcaaaacc agtcatcaaa acctttttat ctgggaaatt ttgtgcaata
     6601 atttctttca agccggcctg actaccaaga gcatcagggt caggattttg atggcgatgg
     6661 ataataatag tttggtgagc ttttatttta tctaaaattg tttcaaaagt tgttatcatg
     6721 ctttaatctt tctttttcaa aaagaggaaa ataaccgttt aacataatct tcaaaaaacg
     6781 gtttgtgtca taaggaggtg tgcgttatgt taagtggcta atgctagaat tttttaagat
     6841 tgtcaaagct cataaattga cattttatct gaaaatcata tcctatttta ttatagcata
     6901 aaagtaagct ctagataatg gtaaattaat ctaggaagaa aagaggttag ttatcagtta
     6961 tgatactatc aaagctagtt ttgcaaatgc aagtgaaaaa atagttttta agtgtcttaa
     7021 gtaatcatat caactttctc tttaaacaat tagtgctttt cctaaaaaag tgtgctaaaa
     7081 taaacatagt ttagtaattt tgggaggaat ttatggcatt agcaaaaatc gtttatgcca
     7141 gcatgacggg aaatactgaa gaaatcgctg atatcgttgc aaataaattg caagaattgg
     7201 gccatgatgt tgacattgat gagtgcacaa cagttgacgc ttcagagttt gagaatgctg
     7261 atatcgctgt cgttgcgact tatacttatg gtgacggtga cttaccagat gaaatcgttg
     7321 atttttacga agatttacaa gatttagatt tagaaggtaa aatctatggc gttgtcggct
     7381 ctggtgacac tttttatgac tatttttgca aatctgttga tgacttttca gatcaatttg
     7441 cgcttactgg tgccgtcaaa ggtgcagagc cagtcaaagt agatttggca gcagaagatg
     7501 aagacatcga tcgtttagag gcctttgcag agcaactctc acaggctgtt aataatctat
     7561 aaaactattt agtaaaaatg tcagggactt ccttggcatt tttagatttt taacctaaaa
     7621 taaagggaat gtcacttcag ggtaggaatt gaaaaaacaa tcagcttcac cttgcttctg
     7681 atcctcttat taactataat aaaaagataa tctaatacat ctagaaaagg aaagttatgc
     7741 gtttagaaga gatacgacaa gaaatcaatg gtattgatca ccacttggtt gccttattag
     7801 aaaagcggat ggcacttgta gagcaagtaa cagcttataa actagccaat cacttgcctg
     7861 tcttagatca ggcgagggaa aatcagatcc tagatagggt ttcttatctc gttaaagacc
     7921 aagcatttga gccagctatc catgagactt ttaaaaccat tatgtctctt tcacggcagt
     7981 atcaaacgca acgcttaaca ggtggtgaca ttaatgatta aatcaattgc aacactgcct
     8041 aaaccctcct taaaagaagc gttaggacta ataggcttgg cgcttcccat aggggccacg
     8101 gttggagtgg ttgatgtgat ttttggtaaa gggcttttgt ttctttccga atatcgcgat
     8161 caccacctgt tcttgcttct tccttttctt gccctagcag gtcttgttat cgtttttctt
     8221 tacgataagt taggcaaaga ggttcgtcaa gggatgggat tggtttttca ggtaggacat
     8281 ggtcaaaaag atcagattcc tcctattctc attcctctta ttttgttctc gacttgggta
     8341 acccacttat ttggagcgag tgcgggtcga gaaggggtag ccgttcaaat aggagctacc
     8401 atctctcatt attgtcagag atttgtgact agtcaagaag ccgcacgaca ccttttgatt
     8461 atggggatgg cagccggttt tgcaggactt tttcaaacgc cgattgctgc tgtcgtattt
     8521 gcccttgagg ttttgttggt aggaacgctt cgctactgcg ctttattgcc ttccttagtt
     8581 gctgcttgcg tggcttcttg gacctctcat tctttgggat tagagaaatt tacgattgtt
     8641 cttgaagaaa cattgaccat aactccctta acattggtta aattaattgg gttaggcctt
     8701 atttttggtc tggtgggaaa tagttttgcc tatttacttg gctggtttaa accttacctc
     8761 agtcaaaagc taccaaatcc ttatttccgg attgctttta tcggtgcttt gttatctatc
     8821 tgtctgatga ttggtcacgt cggaagatat agtggtctag gaactcattt gattgcggca
     8881 gctttttctg gccaaactat cctaacttac gactggcttt taaaaatgat cgtgacggtg
     8941 attagcttat ctgcaggctt tcaaggtggt gaagtgacgc ctctatttgc tattggagct
     9001 tctttaggca tcgttttggc cccttactta ggtcttcctg tactgttggt tgctgcactt
     9061 ggttacacca cggtatttgg aagtgcaaca aatacctttt gggcccctat ctttattggg
     9121 atagaggtct ttggtccaga gaatgcccta gcatattttg tcacctcggc tgcagcctat
     9181 atggttagtc acagacattc catttacagt tatcaaaaag tagtcatgat caatttaaaa
     9241 gacatgacgg taaatcagat ggatttaaaa aaatagcttt acaataaaga agctttttgt
     9301 tagaataaat ctcgtgtgta atggacacac gaaaattacg gctaatccgc taagacaagt
     9361 acttaagatt agtaagatag gagaataaaa atgaatccat taatccaaag tttgacagaa
     9421 ggtcaacttc gctctgatat ccctaacttc cgtcctggtg acactgttcg cgttcacgca
     9481 aaagttgtcg aaggaactcg cgaacgtatc cagatctttg aaggtgttgt tatttcacgt
     9541 aaaggtcaag ggatctcaga aatgtacact gttcgtaaaa tctcaggtgg tatcggggta
     9601 gagcgtacat tcccaatcca cacaccacgt gttgacaaaa tcgaagttat ccgccacggt
     9661 aaagtccgtc gtgcgaaact ttactacttg cgtgcattac aaggtaaagc tgctcgtatc
     9721 aaagaaattc gtcgttagtt tgaaccgaaa cgtaacgtaa tagaataaaa agactagagt
     9781 ctctagtctt tttatgtcgt cgtgacaatg tgacaattgg tgattaacgc tatgctcgta
     9841 ggacactttg aaagttcctt agcagttata attagtatat tgtaataaca aaatgaagca
     9901 aaataaactt tcagttatct gatatttcat cttgcattac cttattttct aggttaaaat
     9961 agaagacaag gtgaatataa gataggcccc ttagttcaat ggatataaca actccctcct
    10021 aaggagtagt tgctggttcg attccggcag gggtcattat tgtcactgaa aaagccttta
    10081 catcaaaggc tttttgtttt attccggttt taaaaggggc ataaaagggg cagtttgttt
    10141 atttataatt tctttcatgt ttacagttgt gtgactgtaa atagataatg ttgtttttgg
    10201 atcgctgtga ccaactctat ccattatcgc atttagcggt atcccttttt ctgctaaaaa
    10261 tgatatatgc gagtgtctaa ataagtgcgt gtgataatct ccgtaaattt tcaatcgctt
    10321 attgatgtgt gcatttaaaa ttggtaaacc ttttgaatat ggaaagctgt tagcactctg
    10381 cttgtgatta atctatcgta tgttaaaagt gacatttaaa ttaaatcatt ttttatacat
    10441 atatttcaac aggatttatc atattggaaa atagcggtgc ttctattggc attttactat
    10501 tgacaggaat ttccctgtct tttgtctcct aaagaagatc agctttgatt tctaacttga
    10561 ttagagtggg cttggtactg tttatgaatt atcagtatat actttctgga gatcaaaaag
    10621 gaaaggaaca gctaaagagg tgtatgtgtt accattagag gaatagaaca tcgcaagact
    10681 cgtttattca gtcattacga tacctgtttt atttgggaaa taactataat attaagtgaa
    10741 tttgtgatat aatgaaaggt atgaattatc aagattatat atgggatttg ggaggtacct
    10801 tactcgataa ttacgagctt tcaacccaag cttttgtcca aacgctagct tttttcagcc
    10861 ttccaggaga tcacgatgct gtttaccaaa aattaaaaga atcaaccgct atcgctgtgg
    10921 caatgtttgc tcctaatgag ccagaatttt tgcatgtgta taggctaaga gaagcagaca
    10981 aattggcaca acccatttgg tgtttgggag ctaaagaaat tttggaaaag atagcgactt
    11041 caggttcgcg aaatttttta atttctcatc gagattgtca ggtgaaccaa cttttagagc
    11101 aagctgggtt gctaatctat tttacagaag tcgtgacagc ttcaaatggc tttgctcgga
    11161 aaccaaatcc tgaaagtttg ttttatttaa aagaaaagta tgatattaat agtggattag
    11221 taattggaga tcggctaatt gataaacaag caggacaagc agcgggcttt aataccttgc
    11281 ttgttgacgg tagaaaaaac ctattggaga tagtaacgta gatgattgaa gaaaataaac
    11341 attttgaaaa aaaaatgcaa gaatacgatg ccagtcaaat tcaggttcta gaagggctgg
    11401 aggctgtccg catgcgtcca gggatgtata ttggctcgac agctaaagag ggtttgcatc
    11461 atttagtctg ggaaattgtt gacaactcaa ttgacgaagc attagcaggt tttgcctctc
    11521 atattaaagt ctttattgaa gcagataatt ccattacagt agtagatgat ggccgtggaa
    11581 ttccagttga catccaagcc aagacaggac gtcccgccgt tgaaacagtt tttacagtct
    11641 tacacgcagg tggtaaattt ggcggaggcg gctataaggt ttctggagga ttgcatggtg
    11701 tagggtcatc tgttgttaat gctttatcaa cacaattaga tgtgcgtgtt tataaaaacg
    11761 gccaaattca ttaccaagaa tttaaacgcg gggcagttgt agcagatctt gaggtcattg
    11821 gaaccactga tgtgactgga acaacggtac actttacacc cgatccagaa atttttaccg
    11881 aaacgactca gtttgattac aatgttttag caaaacgtat tcaagagtta gcctttttga
    11941 atcgtggttt aaaaatttcc attacagata agcgctcagg tatggaacaa gaagaacatt
    12001 tccattatga aggtggaatt ggttcttatg ttgaattttt aaatgataaa aaagatgtta
    12061 tctttgaaac gcccatctat acagatggtg aattagaagg tattgcagtt gaagtagcca
    12121 tgcaatacac gactagctat caagaaacag tcatgagttt tgctaataat attcatactc
    12181 atgaaggtgg aacgcatgaa caaggcttta gagcggctct tactcgggtc atcaatgact
    12241 acgctaagaa aaataaaatt cttaaagaaa atgaggacaa tttgacagga gaagatgttc
    12301 gtgaaggttt gacggcggta atttctgtta agcatccaaa tcctcaattt gaaggtcaaa
    12361 ccaaaacaaa attgggcaac tcagaagtgg ttaagatcac taatcgtctc tttagtgagg
    12421 cctttcaacg ttttcttttg gaaaacccac aagttgctcg taagattgtg gaaaaaggga
    12481 ttttggcttc taaagctaga attgcagcta agcgagcccg cgaagtcacc cgcaaaaaat
    12541 caggcttaga aatttcaaac ttacctggaa aattagcaga ctgttcgtca aatgatgcta
    12601 accaaaacga acttttcatc gtcgaaggag attcagcggg tgggtcggcc aaatcaggtc
    12661 gtaaccgaga gtttcaagct atcttgccta ttcgcggtaa aattttgaac gtggaaaaag
    12721 caactatgga taagattctt gccaacgaag aaattagaag tctttttacc gctatgggta
    12781 caggttttgg tgcagatttt gacgtgtcaa aagctcgcta ccaaaagctg gttatcatga
    12841 ccgatgccga tgtggatggc gctcatatta gaaccttgct tttaaccttg atttaccgct
    12901 ttatgaggcc tgttctagaa gctggctatg tttatatcgc ccagccacct atttatggtg
    12961 ttaaggtcgg tagtgagatt aaagagtaca ttcagccagg tattgatcaa gaagaccaat
    13021 taaaaacagc tcttgaaaaa tatagtattg gtcgttcaaa accaactgtt caacgttata
    13081 aaggtcttgg ggaaatggat gaccatcaac tttgggaaac tactatggat cctgaaaatc
    13141 gtttgatggc gcgtgtgaca gttgatgatg ccgcagaagc agataaagta tttgatatgt
    13201 taatgggaga tcgtgttgaa ccaagacgta atttcattga ggaaaatgcg gtttatagta
    13261 cactggatat ttagtcacct ttttagtttc acaaggaatc tgctaccaaa gaggacgaat
    13321 tgactaaaaa tcatgatgca tgatgccaac agctttgtta gttagtacgt cttcatcttg
    13381 agggacagcg ttaatgcata ggtattgaga ccgcccctta atacctatgt tagtccttat
    13441 taagaaagcc ttgtgagtcg ctggtacgag attgttgaat tagtcaaata tattttgaaa
    13501 tgcattttaa agtatgttat aatcgtaatg ttatagtgta ttttaaataa aattttaata
    13561 aaaggcgatt gaggaatttc agtttttagt tattactgga acaatgttga taaatcgtgt
    13621 ctaaataata aggagattca gatgtcaagc ggaattatct tgctgattgt ggctatagtc
    13681 ctactagtga ttatcgccta tctagtgggt gtcatcatac gaaagcgtaa tgattcccta
    13741 attaccagtc tagaagaacg aaaacaggcc ttgtttgctt tgcctgttaa tgatgaaatt
    13801 gaagaagtaa agtcacttca tttgatagga cagagccaaa cctcttttcg ggaatggaat
    13861 cagaaatggg tagacttaac tgtaaattcg tttgcagata ttgaaaatca tatttttgaa
    13921 gctgaaaatt tgaatgatac gtttaatttt attcgcgcca agcatgagat taatagcgtt
    13981 gaaagtcagc ttaatcttgt tgaagaagat atcgcttcta ttcgtgaggc acttaatatc
    14041 ttaaaagagc aagaagaaaa aaatagtgct cgtgtcaccc atgctcttga tttatatgaa
    14101 aagctccaag cttctatttc tgagaatgaa gataattttg gttcaactat gcctgaaatt
    14161 gacaaacaga tgaaaaacat tgaaactgaa ttttcacagt ttgtcgcact caactcatca
    14221 ggtgatcctg tagaagcttc tgaagttctg gatagagcag aagagcatac tattgctcta
    14281 gggcagatta cagagcagat tccagctatt gtcgccaagt tggaagatga ttttccagat
    14341 cagttagatg atttggaaac aggatatcgc cgtttacttg aagaaaacta tcattttcca
    14401 gaaaaaaaca ttgaggcacg ttttcaggag attcgtgagt ctattcgtgc caattcatca
    14461 gagttagtta cacttgactt ggatcgtgct agagaagaaa acacgcatat tcaagaacgc
    14521 attgattctc tttatgaagt ctttgagcgc gaaattgccg cttataaggt agctgctaaa
    14581 aatagtaaga tgctacctcg ttacctagca catgtgaaac gtaataatga acaactcaaa
    14641 gatgaaattg cacgtttatc acgtaaatat attctaagtg aaacggaaag tctgactgtt
    14701 aaggcatttg agaaggatat taaagagatc gaagacagta cacttgctgt tgcagaacaa
    14761 tttggtttac aagaaaaacc attttcagaa ctgcaagtga cttttgaacg cagtataaag
    14821 acgcttacta atgtcgagtc aggtcaaatg gatgtttttg cagcagttaa agatattgaa
    14881 aaaattgaat cacaggcacg ccataacctt gatgtttatg ttactcagct tcatatgatt
    14941 aaacgttata tggaaaaacg tcacttgcct ggaattccac aagactttct tagtgctttc
    15001 tttacaacga gttcacagtt ggaagctttg atggatgagc ttagtagagg acggatcaat
    15061 attgaggcag tgtcacgttt gtcggaagtt gcgacggttg ctattgctaa tctagaagat
    15121 ttaacctatc aagtggttca aaatgctacc ttgactgaac aattactaca atattctaat
    15181 cgctatcgtt cttttgaagc aggagttcaa agtagttttg aacatgcttt gagacttttc
    15241 gaagtagaaa atgattatca ggcttctttt gatgaaattt cttatgctct tgaaacagtt
    15301 gaacctgggg taacagatcg gtttgttaac tcttatgaaa aaacacgaga gcacattcgt
    15361 ttttgatact tgaaagtcgt gatattctca cgacttttta ttagcttttt ggaccaatac
    15421 gtgtttttga ctagaatctt ctttttaatg atcaaacgaa gaagtagtaa cagtgttttt
    15481 tggtattgag aggatagtta ttttttcaaa aatcttttcc aaaaggattt ggttttttca
    15541 ggaggttgtt tgctaagttg atcatttttt gtctgcttta agatgacttc taaacgcgtt
    15601 tcctttagat ttattgcgtg gtcggtatga aggataaacg caaaaggtga agtcatatgc
    15661 gtttctgtaa taatagtaac aggtaaatgg ttttcttttg ctaatttcat atagagtatt
    15721 tgaagttgag gtgccagctt ggaagagatt tttaagtgta aaggttgata gactaactga
    15781 aggctcggta attctctttt caaatagtct tttactgttt tagtttgagc ttcgtctaat
    15841 aaagcactta aaacgactcg ttcagcatac gttcctagat agtagcgttg ctgctcagga
    15901 tttaatcttc tttctcccca ggctcctttt aatagcttat cttctaaatt agtcatagat
    15961 accctcgctt ctttataata gtttctttat tatatcgatt tctacaataa aataccaatt
    16021 tgaaaatttt cggtaaatgt gttaaaaaac aagaaagaaa gtgatttttc ttgcaaaaaa
    16081 caaaggaagc ttttcatgag attgcttttt aagttgatta aaggcctagt ttgtggtatt
    16141 atgaacatgt aaaatattaa aactcataag gagagtatta caatgtcaat tattactgat
    16201 gtatacgctc gcgaagtcct tgactcacgc ggtaacccaa cacttgaagt agaagtttat
    16261 acagaatcag gtgcattcgg acgtggtatg gttccttcag gagcttcaac tggtgaacat
    16321 gaagccgttg aacttcgtga tggtgacaaa tctcgttacc ttggtctagg tactcaaaaa
    16381 gcagttgata acgttaataa cattatcgct gaggcaatca tcggttacga tgttcgcgat
    16441 caacaagcta tcgaccgtgc aatgatcgct cttgacggta ctcctaacaa aggtaaactt
    16501 ggtgctaatg ctattcttgg tgtttctatc gctgttgctc gtgcagctgc tgactatctt
    16561 gaagtgccac tttacactta ccttggcgga ttcaacacta aagttcttcc aactcctatg
    16621 atgaacatca tcaacggtgg atcacactca gatgccccaa ttgcattcca agagttcatg
    16681 atcatgccag ttggtgcacc tactttcaaa gaaggtcttc gttggggtgc tgaagttttc
    16741 cacgctctta agaaaattct taaagaacgt ggacttgtta cagctgtagg tgacgaaggt
    16801 ggatttgctc ctaaatttga aggaactgaa gacggtgtag aaactatcct taaagctatt
    16861 gaagcagctg gttacgaagc tggtgaaaac ggcattatga tcggttttga ctgtgcatca
    16921 tcagaattct acgacaaaga acgtaaagtt tacgactaca ctaaatttga aggtgaaggc
    16981 gctgctgttc gtacatctgc agaacaagtt gattaccttg aagagttggt taacaaatac
    17041 ccaattatta ctatcgaaga tggtatggat gaaaacgact gggatggttg gaaagttctt
    17101 actgaacgcc taggcaaacg tgttcaattg gttggtgacg acttcttcgt tacaaacact
    17161 gaataccttg ctcgtggtat caaagaaaat gcagctaact caatccttat caaagttaac
    17221 caaatcggta ctttgactga aacgtttgaa gctatcgaaa tggctaaaga agctggatat
    17281 actgccgttg tatcacaccg ttcaggtgaa actgaagatt caacaatcgc tgacatcgca
    17341 gttgcaacaa acgctggcca aatcaaaaca ggttcattgt cacgtacaga ccgtattgct
    17401 aaatacaacc aattacttcg tatcgaagat caacttggtg aagttgctca atacaaaggt
    17461 atcaaatcat tctataactt aaaaaaatag acggtaagac agaaatcggt cattcgtaga
    17521 atgcgatttc gtcgtcgcac ccccgtcagg ctgactaggt tggtcacgac aaaaggagtg
    17581 aacatccagt cagctacgac gcaaaagtta aagattaaag aatagaaagc ttgggaaaat
    17641 cccaagcttt ttgctttcta aatagtaaaa atttactgtg ggctaattta tcctgagcta
    17701 atgtattagc gaggtaaagt tattgaggaa ggcttggatt tgtactgcct ctaaaaagtt
    17761 ggacactata ttttaaatac aggactaagt ccttttatac caattgtcaa gcacatcaag
    17821 gttttaactg aaaaaatgtt ttagacaata gcctaggttt agctgttgtc ttacttgttg
    17881 tgctctgatt agcataaaaa agtgtacaag aaaaaaacct tgcctagtat ttttaagatc
    17941 aaggtgttac aatgatagag caacaacgac tttaatgatt ttgggtcgaa gcgtaattgt
    18001 aaagtttgtt atgcgttatg aggtaaagca ttgtctgaca aggcaatgtc tagaggcaat
    18061 cgtatgtggc ttggttgaag ctgtttgcga ttgccttttt cgtttctcat agaagtctgc
    18121 gatatgacaa ggattggtat gactagcaaa agcaatgtca tggatacact tgaaaagaat
    18181 ctttgaagca taaggattcc cacgtttggt aatgtgctct tgagctagat agttgccaga
    18241 ctcataatgt ctaaagtcaa tcccaatgaa agcattaatt tgattagcag attgaaaacg
    18301 acgaatagca ccgagttcgc caataatact tgttgcagtt gtttctgcga tacttggaat
    18361 agagcgtaga atcttgtctt ctggtaaagg ttgagccaac gccaccatct tatcaaaaat
    18421 agcttgacga cgttcagaaa gtctaagtaa ttctttggca tagtagcgaa cctcttctat
    18481 catcggagag gttttcgtaa cagtaaaata agactgcttg gctaatgaga caagtttttc
    18541 cactaagtag atcccacgct tgtcagagat acgtttagag gtagattgac ggatgatagc
    18601 tgacaatgct ttgtcagcta gctccagtac aaagctatta catggaaaag ccgttaccac
    18661 attccagtat tactcaccag ttggtgcaaa taagatgtgt tccagttcag gaaaagtgac
    18721 ttgtaagatc ttgtgaaggc gattcttaac tctcgaacaa tattatcctc agtcaatttt
    18781 tgatagaagc gactcaagtc acgtagcagc tgataaactt cttcctgaac gtaagttggt
    18841 tttctaacta gaataaattg agactgagcc aatttttcag tgtctaactt atccgcttta
    18901 cgcacccgta gactatctag ttttctaaag gattgagttg tgtataagcg tagccatttt
    18961 tctcaaggaa ggactgaagc cgacgagaat agactcctgt tgtgatggtc tcccttttgc
    19021 cttttaaaca atagtatagc cgtttttcaa gatgttatta atgatttttt cctttattct
    19081 agaagaataa gtctgatact gtttcttctt aataatctca atgccctaac agtccatcag
    19141 tcgaacggta tttctcaaat tactgcagtt gactcttgcg ttcagttccc tcaccttgtg
    19201 gatgccgttt agaacaatat tagcttgctg aattagcttg ctgagccttt tggtaatgtg
    19261 aacaaagcat ctttatcact caaggagaag acaggttctt gtggtaagtg tccaacaagg
    19321 tcacgataaa ctcatcgtac cgtttttggc ggaagtctag aaatgcctta tgaatgtaag
    19381 cctcagaaac gtctctaaaa ctaaacaaga aatacaagaa caaatgccct tgattctggt
    19441 acaaatgctg tatcaggttc aggtattgcc tatctgcgat aatgacactc tgcttttcct
    19501 taacaatatc tttgaaagga atgatttcga cattgacagg cataaccgtt gcaatagctg
    19561 gcgggaagta aatcgagagt gcattggtca tcaaatccag cgcagcagtg ttattggtca
    19621 aaagatagac aggtatcggt ggcaaatatg tttttaggag ttcctctaac tgtatcgtga
    19681 agagcagtaa atgataggac ggcagtttcc ccacgatgcc ttctgcgctc atccattcct
    19741 caacgatggt ttttagagta ttgtagaagc tcttgtttcg tttttgctgt cttctgaggt
    19801 aatggaacaa gtgtatatca ggtaacaaaa cttgaagatt actgataaat agacgtgaga
    19861 aggaaaccaa aatccgtttg aaaggaaggg agtttaggat attattgcct agtagtggac
    19921 gcagggatgc tttcaaggtt tttccatttg tttttgtcat caccaactca aacaattctt
    19981 tcactttttt aggtgtccat ttatccttat ggaaagaatt attggtggtg caaaaacata
    20041 agaaaatata atccaaatcc tcatcagtta aatcaggatg gtaccatttt ccgatgattt
    20101 cctgactggt cattttgata tctcgataga tagacagttt tttcaagtgt ttgaatgcat
    20161 ctgtctgagg gatccccaag ttatcatgtc gccgtttcca tataagggat atcagaatgg
    20221 caaagtatga aaattcataa ggggctttac tggcatcatt aagtgtgatg gcttgattgg
    20281 agtttataat cagcgaaacc actttattca ttgatgtttt atcaaaatca taaatggtca
    20341 taccaaactg atagtgcaac aaggcgatca gaaagcggat acggtattct ggtccaacaa
    20401 tatggttttg ccgaacgttt aaacctacct ttttcaagta tttccgacaa ttggtcctga
    20461 tacggtaagc ggtggcttgg gaaatatact ctcgtttaat gaagtcgtgt aggctcagct
    20521 ctcctggttc aattaaaaaa cataacatct ttaagaatat cgaggtttga tagagtttct
    20581 taaaataagg cattttaagt tggtaggtct tataggggat agaaacagtg tcgtcacaaa
    20641 tggttaaggt gagggtgtct tctaaatcct taatcatttc aaagagtaag ttgtagacac
    20701 gttgtttttt gagttcggtt tcctgacaca actggtctat ggagacttcg gaaacgtcta
    20761 acaaaatgtt gagcagtgat aatttatctt gtaatttggt ttctagatga aggtgtaaca
    20821 taactgaact cctttcattt ttatagcaga aactcgtatt tatttaatta tcacataatt
    20881 aaataaaaca gtcaaataat tcaatggtga cgcgtgttta aggagtattg agaatgtcag
    20941 atataagcaa aatgcagctg aatattctta attttaggta tgaaaaagcg tcgggattga
    21001 taaaaaatct attgaattgg gtaaatttaa gttgatataa taagttgatt agaaaaatta
    21061 ataattcatt taaattctaa tcagctgtaa cgttccgggg cgtgttaaac tgtctgaaca
    21121 tagaaaatac aggtttctac ggtgactaaa ataagctaag gaggattcct taaattctgt
    21181 gataggaacg taaactctct acaagagtag agcacgtcat cagtcagtct gggtgtctac
    21241 tggctgacaa cgtcaaataa gataggcatg aaaaaataag ggggaataca gaatgttttt
    21301 aaaacaccaa gatgtgaaac aaaaaaattg gagaatgcgt aaggtcaaaa aagtctttgt
    21361 tagttcatgt atgcttttaa cagtgggcct cggagttgcc gtactactgc attcagccaa
    21421 tctaatggcg tgatggtcgt aaaggctgcg gaagctgaag aactgccaga caatttaatt
    21481 gattttaaag gaacttggga agtatctgcc gatggctctt ctggtcgctt ctattcagac
    21541 ggtgctacag gtcaatataa gtttcacctt attccagctt cagatgttaa aaatccggga
    21601 tggcatgaac ataataaagt taaagatagc tatgtcaaaa taaccaaaga gtctattgca
    21661 gctagatata caaataaaac gaaacctcca tattctgtag cgtttaaggt caacactaaa
    21721 tctttaataa aagatcatga ctataagata acttttgagc aaggttcaat tgcgtcggga
    21781 ataacagttg attatcgtat aggcagtgct tttaataaaa ctaaagatga ttctttcaac
    21841 atttcagatg agagtaaata tgcttctaag gtaacaatag aaggtgagga aagaggtttt
    21901 ataaatagga aaccaggaac taaaacaata tcttttagag ctgtagaaaa aggaactaaa
    21961 tctcttgtat tgttatctaa agttaatgaa aaaacccaag tagatcttga tgtcgagttt
    22021 aaaaacttca aaattattga tgttaccaac ccaagccaat tagataaagg agttgcttac
    22081 gttggaaaca aaaatgtaga attgacatta aaatcagacg atggaagaac aaacttcgaa
    22141 ggtgatgaga taagcctttt taagcctaat ggagatttgt taaagaaaat tgaagttaaa
    22201 gaaggacaaa aaaatcctat atcaataact ttatctgaag atcaagccaa atctttaaaa
    22261 aacaaagaaa agttaaaagt aagcattaaa caaaagcaat caaaaaagac ttctaaagac
    22321 tttttctttg aggtaggaat tgatcctaaa gttaaagcaa agcaacaaga aaaactctta
    22381 gaactagaca aagtaaaaaa acaaattgaa gactcaatca atggtgatgc atggctacca
    22441 gaaaaatcgg aaggcgaaaa accagtacaa aatactaata aagaattaca gttacaagaa
    22501 ctgaacaaga agtatcagat ggccaaagag gcaattgaaa gtgctacaac tcttgacgat
    22561 gttgaaactc agtttgataa atacacaaaa gttggagata aagataaata cccggattct
    22621 ttacgtaacc aatatactcg aggagataaa gataaagaaa tagaaaaagc taaaaaatca
    22681 ctgggtgatt taagcgataa agtgaatgga aagattgaag aagataagtg gctatctgac
    22741 gaagttaaaa aaaaacaaca gcaagaatta gaagcgcgta aacaaaaagt aaacgactct
    22801 cttaaaggat ctgatagttt aaaatcattg agagaaacag tggaaaaagc ttcttctaaa
    22861 aatcagaaaa aaccagaatc ttttgaagat gtttatgttc ctggaaatga agaaactgaa
    22921 aaaacaaaag ttcgtgatat acttcaaaaa acttatcaaa aaacagagca aaatattgaa
    22981 acagatccat ggttgagtcc ggaacagaaa aaagctcaaa aagaaaacgc taaagcaaga
    23041 ttagatgcag gtttgaaagc tgtcgaaact acagaaagct tagataaact taaagaagtt
    23101 gagagtgact tccttgataa agaaaaaaat ccagattcaa ttccaaatca acataaagct
    23161 ggaactcctg aagttgctcg caaaactttc ttagataact ttgaaaaaga agccaaaaaa
    23221 gagattgaat ctattgataa agatgatacc ttaacggcaa atgctaaaca agtagctaaa
    23281 gataaagtgg cacaacagct acaagaagct acagctaaag tagagaaagc acagtcgttt
    23341 gatgatttga agaacattca agataagttc aattctgaat taccacacac accaggtaag
    23401 ccgcttaaag atcaacaatc tgatgctatt gcagaattag agaagaagca gcaagaaatt
    23461 gaaaaagcta ttgagggtga taaaacatta ccaagagacg aaaaagagaa acaaattgct
    23521 gactctaagg aacgcttaaa atctgacacg caaaaagtta aagatgctaa aaatgctgat
    23581 gctattaaaa aagcatttga agaagggaaa gtggatattc ctcaagcaca tatcccaggt
    23641 gatttgaaca aggataaaga aaaacttctt gcagagttga agcaaaaagc agatgatact
    23701 gaaaaagcga ttgattccga taaaactttg acagcgaaag aaaaagaaga gcaaaaagcg
    23761 aaaacaaaag aagaacttca aaaagcaaca gaagctgttg gagcaattga caatcgtgaa
    23821 gaactagata aaaaagtccc agaacttaag aaagctattg aagacactca cgttaaaggt
    23881 aatcttgaag gtattaagaa taaggctatt gaagatctta aaaaagctca tactgaaaca
    23941 gttgctaaaa taaatggtga tgataccctt gacaaagcta ctaaagaagc tcaagtgaaa
    24001 gaagctgaca aagctttggc agcaggtaaa gaagctatca ctaaagcaga tgatgctgat
    24061 aaagtaagta cagctgttac agagcacaca ccaaaaatta aagcagcaca taaaactggt
    24121 gatcttaaaa aagctcaagt agatgctaac acagctcttg acaaagcagc tgaaaaagaa
    24181 cgtgaagaaa tcaataatga tatcacatta acggcaaaag acaaagaaca acaactgaaa
    24241 gaagttgaga cagctcttac taaagctaaa gataacgtta aagctgctaa gacagcagac
    24301 gctatcaatg acgcacgtga taaaggcgta gcaacaattg atgccgttca taaagcaggt
    24361 caagacttag gtgctcgtaa gtcaggtcaa gtcgctaaac ttgaagaagc agctaaagca
    24421 acgaaagaca agatttcagc tgatccaact ttgacaagca aagaaaaaga agagcaatct
    24481 aaagctgtta acgctgaact taagaaagcg atagaagctg ttaacgcagc tgacacagct
    24541 gacaaggttg acgatgctct tggtaaaggt gtcacagaca tcaagaacca acataagaca
    24601 ggtgacccta tcgaagctcg tcgtggatta cacaacaagt caatcgacga agtggcgcaa
    24661 gcaactaagg acgctatcac agcagatacg actttgactg aagctgaaaa agaaacacaa
    24721 cgtggcaatg ttgataaaga agcaactaaa gctaaagaag aacttgctaa ggctaaagat
    24781 gctgatgctt tagacaaagc gtatggtgac ggtgtaacca gcatcaagaa ccaacacaag
    24841 tcaggtaaag gtcttgacgt tcgtaaagat gagcacaaga aagctcttga agctgttgct
    24901 aaacgtgtca ctgctgaaat tgaggctgat ccaaccttaa caccagaagt gagagaacaa
    24961 caaaaagcag aggttcaaaa agagcttgaa cttgcgactg ataagattgc tgaagctaaa
    25021 gatgcagatg aagcagacaa agcttacggt gacggtgtca cagcgatcga aaatgcccac
    25081 gttattggta aaggtatcga agctcgtaaa gaccttgcta agaaagacct tgctgaagct
    25141 gctgctaaga caaaagctct cattattgaa gacaaaacgc ttactgatga tcaacgtaaa
    25201 gaacagttat taggtgttga tacagagtat gctaaaggta tcgagaatat tgatgcagct
    25261 aaggatgctg caggtgttga taaagcatat agtgacggtg ttcgtgacat cctggcacag
    25321 tacaaagaag gtcaaaacct taatgatcgt cgtaatgctg ccaaagaatt tcttcttaaa
    25381 gaagcagaca aagtgacgaa actaatcaat gatgatccaa ccttgactca tgaccaaaaa
    25441 gttgatcaaa tcaacaaagt tgaacaagct aagttagacg caatcaagtc tgttgatgat
    25501 gctcaaacag ctgatgctat caatgatgct cttggtaagg gtattgaaaa catcaacaac
    25561 caataccaac atggcgatgg cgttgatgtt cgtaaagcga ctgccaaaga cgatcttgaa
    25621 aaagaagctg ctaaagtgaa agctcttatt gctaaggatc caaccttgac tcaagctgat
    25681 aaagacaagc aaacagcagc ggttgacgca gctaagaaca cagcaattgc agcggttgat
    25741 aaagcgacaa cagcagatgg tgttaaccaa gaacttggta aaggcatcac agctatcaac
    25801 aaagcttacc gtccaggtga agctgttaaa gcacgtaaag aagccgctaa agc
//
LOCUS       DATWEK010000024        25824 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.024, whole genome shotgun sequence.
ACCESSION   DATWEK010000024 DATWEK010000000
VERSION     DATWEK010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25824
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.024"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            222..1505
                     /locus_tag="VCR92_001206"
     CDS             222..1505
                     /locus_tag="VCR92_001206"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEP4268274.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDKAFNKIKKDLNAPGF
                     RKGHMPRPVFNQKFGEEVLYEDALNIVLPEAYEAAVTELGLDVVAQPKIDVVSMEKGK
                     EWTLSAEVVTKPEVKLGDYKNLVVEVDASKEVSDEDVDAKIERERQNLAELIIKDGEA
                     AQGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEDQLVGAKAGDEVEVNVT
                     FPESYQAEDLAGKAAKFMTTIHEVKTKEVPELDDELAKDIDEDVDTLEDLKVKYRKEL
                     EAAQETAYDDAVEGAAIELAVANAEIVDLPEEMIHEEVNRSVNEFMGNMQRQGISPEM
                     YFQLTGTTQEDLHNQYSAEADKRVKTNLVIEAIAKAEGFEATDSEIEQEINDLATEYN
                     MPADQVRSLLSADMLKHDIAMKKAVEVITSTASVK"
     gene            1717..2292
                     /locus_tag="VCR92_001207"
     CDS             1717..2292
                     /locus_tag="VCR92_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEP4268275.1"
                     /translation="MKLDVFAGQEKSELSMIEVARAILEERGRDNEMYFSDLVNEIQN
                     YLGKSDAGIRHALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEEDEDG
                     AQKRKKKRVNAFMDGDEDAIDYRDDDPEDEDFTEESAEVEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDINEEDEEDEEDEEPVL"
     gene            2549..4153
                     /locus_tag="VCR92_001208"
     CDS             2549..4153
                     /locus_tag="VCR92_001208"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEP4268276.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAASTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNSEAVIESRNVEHLYQIPLNLQAQSMDQIVCDHLKLNAPQADMTE
                     WSAMVDKVMNLRKTTKIALVGKYVELPDAYLSVVEALKHSGYANDTAIDLKWVNANDV
                     TVDNAADLLGDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGICLGMQLTCVEFA
                     RHVLNMEGANSFELEPSTKYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKPGSKAAMAY
                     NNQEVVQRRHRHRYEFNNKFRPEFEAAGFVFSGVSPDNRLVEIVELKEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAIKNSN"
     gene            4321..5247
                     /locus_tag="VCR92_001209"
     CDS             4321..5247
                     /locus_tag="VCR92_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEP4268277.1"
                     /translation="MKTIRIAKYLGILFLLITLISVGASFYFFHVAQIREEKSFINNK
                     KRSTNNPLYPAEQSFDALPYEKRQLTNRGLKQVGWYLPAAQKTKKTAIVVHGFTNDKE
                     DMKPYAMLFHDLGYNVLMPDNEAHGESEGNLIGYGWNDRLNVMAWTDQLIKENPESQI
                     TLFGLSMGAATVMMASGERLPAQVTSLIEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKRPTLFIHGDKDDFVPTKMVYDNYKATKGPKEI
                     LIVKGAKHAKSFETNPEQYQKKIAAFLKKVEK"
     gene            5301..5386
                     /locus_tag="VCR92_001210"
     tRNA            5301..5386
                     /locus_tag="VCR92_001210"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5335..5337,aa:Leu,seq:aag)
     gene            5593..6474
                     /locus_tag="VCR92_001211"
     CDS             5593..6474
                     /locus_tag="VCR92_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEP4268278.1"
                     /translation="MAIVSAEKFVQAARENGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKVCQSLITNLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLAKTAEVVKIAHAKGVSVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPENWEGLALDHLEKLTAAVPGFPIVLHGGSGIPDDQI
                     KEAIRLGVAKVNVNTESQIAFSNATREFARNYEANEAEYDGKKLFDPRKFLAPGMKAV
                     QGAVEERIDVFGSANKA"
     gene            6856..7044
                     /locus_tag="VCR92_001212"
     CDS             6856..7044
                     /locus_tag="VCR92_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEP4268279.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            7196..7561
                     /locus_tag="VCR92_001213"
     CDS             7196..7561
                     /locus_tag="VCR92_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEP4268280.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSAIKD
                     NFQSLLRKENYAKGVVVKSTDLGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LTADMVNVYVQNIKVVGEN"
     gene            7561..9225
                     /locus_tag="VCR92_001214"
     CDS             7561..9225
                     /locus_tag="VCR92_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEP4268281.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQMLSKGLLMGARGNSGVITSQLFRGFGQSIKGKDE
                     LTGKDLAQAFQVGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDDAVEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVTSADFKATPANM
                     SEMINAEHHKSVVGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKTDVEKNKA
                     EVKEFGLIAVVAGEGLSEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVATRTVPQGFTSLLAFDPSKSLEDNVADMSTSLSDV
                     VSGSVTLAVRDTTIDGLEIHENDFLGMVDGKIIVSNPDMEATLKAAFEKMIDEDSEIV
                     TIFVGEEGDQDLAEELAGYLGETYEDVEVEIHQGDQPVYPYLMSVE"
     gene            9462..10352
                     /locus_tag="VCR92_001215"
     CDS             9462..10352
                     /locus_tag="VCR92_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEP4268282.1"
                     /translation="MLGPFIFIAFGVIVILAIVASTLYVVRQQSVAIVERFGRYQKTA
                     TSGIHVRLPFGIDKIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVTDA
                     YYKLMKPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLAESIQELKEANISLNEEQIMSILLTNQYLDTLNTFATKGNQTLFLP
                     NTPSGVEDIRTQVLSALKTK"
     gene            10582..11436
                     /locus_tag="VCR92_001216"
     CDS             10582..11436
                     /locus_tag="VCR92_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEP4268283.1"
                     /translation="MKSKKVVSVISLTLSLFLVIGCAKVDNNKSVNCKPATKQTYNSY
                     SDDQLRSRENTMSVLWYQRAAETQALYLQGYQLATDRLKEQLNKPTDKPYSIVLDIDE
                     TVLDNSPYQAKNVLEGTGFTPESWDYWVQKKEAKPVAGAKDFLQFADQNGVQIYYISD
                     RSTTQVDATMENLQKEGIPVQGRDHLLFLEKGVKSKESRRQKVKETTNVTMLFGDNLL
                     DFADFSKKSQEDRTALLSDLQEEFGRRFIIFPNPMYGSWEGAIYKGEKLDVLKQLEER
                     RKSLKSFK"
     gene            11629..12825
                     /locus_tag="VCR92_001217"
     CDS             11629..12825
                     /locus_tag="VCR92_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEP4268284.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGSKLEE
                     AINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            13088..13639
                     /locus_tag="VCR92_001218"
     CDS             13088..13639
                     /locus_tag="VCR92_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEP4268285.1"
                     /translation="MKTLRKLLSNYKFDIKKFKLGMRTLKTGLSVFLVLLVFHLFGWK
                     GLQIGALTAVFSLREDFDKSVHFGFSRIIGNSIGGLLSLVFFAFNEIFHQAFWVTLLI
                     VPICTMLCIMVNVACNNKSGIIGAVAALLIITLSIPTGQTFIYVTSRVFETFCGVFVA
                     ILVNTDVELIKNKWFNKKHSDVR"
     gene            13706..14077
                     /locus_tag="VCR92_001219"
     CDS             13706..14077
                     /locus_tag="VCR92_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEP4268286.1"
                     /translation="MKEKELRRSMAVFPIGTVMTLTDLSARQIRYYEDQGLIKPERTQ
                     GNRRMFSLNDMDRLLEIKDFLSEGLNIAAIKREYVERQGKLMQKQKALTDADVRRILH
                     DEMLTQSGFSTPSQHIGNFRI"
     gene            14115..15461
                     /gene="glnA"
                     /locus_tag="VCR92_001220"
     CDS             14115..15461
                     /gene="glnA"
                     /locus_tag="VCR92_001220"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEP4268287.1"
                     /translation="MAITVADIRHEVKEKNVTFLRLMFTDIMGVMKNVEIPATKEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGAVAGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMNEIGYKSFNLGPEPEFFLFKMDDKGNPTLEVNDNGGYFDL
                     APIDLADNTRREIVNILTKMGFEVEASHHEVAVGQHEIDFKYADVLKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDNQGNNAFYDETDKRGMQLSEDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPEPIEANIYTMTMEERNEAGIIDL
                     PSTLHNALKALQKDDVVQKALGYHIYTNFLEAKRIEWSSYATFISQWEIDHYIHNY"
     gene            complement(15689..17371)
                     /locus_tag="VCR92_001221"
     CDS             complement(15689..17371)
                     /locus_tag="VCR92_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEP4268288.1"
                     /translation="MTNISLKPNEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLDRVKALVITHGHEDHIGGIPFLLKQANIPIYAGPLA
                     LALIRGKLEEHGLWREATVYEINHNTELTFKNMSVTFFKTTHSIPEPVGIVIHTPQGK
                     IICTGDFKFDFTPVGDPADLQRMAALGEEGVLCLLSDSTNAEIPTFTNSEKVVGQSIL
                     KIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PNGTFIEPSELKNLHASEVLIMCTGSQGESMAALARIANGTHRQVTLQPGDTVIFSSS
                     PIPGNTTSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAMDIGIPKENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGAAVLRDRRDLSEDGVVLAVATVDFNTQMILAGPDILSRGFIYMRESGDLIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDKH"
     gene            complement(17373..17603)
                     /locus_tag="VCR92_001222"
     CDS             complement(17373..17603)
                     /locus_tag="VCR92_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEP4268289.1"
                     /translation="MIYKVFYQETKDQSPRRESTKALYLNIDATDELDGRIKARRLVE
                     DNTYYNVEFIELLSDKHLDYEKETGVFELTEF"
     gene            17887..18585
                     /gene="tsaB"
                     /locus_tag="VCR92_001223"
     CDS             17887..18585
                     /gene="tsaB"
                     /locus_tag="VCR92_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEP4268290.1"
                     /translation="MKTLAFDTSNKTLSLAILDDETLLADMTLNIQKNHSVSLMPAID
                     FLMTCTDLKPQDLERIVVAKGPGSYTGLRVAVATAKTLAYSLNIALVGISSLYALAAS
                     TCKQYPNTLVVPLIDARRQNAYVGYYRQGKSVMPQAHAPLEVIIEQLVEEGQLIFVGE
                     TAPFAEQIQKKLPQAILLPTLPSAYECGLLGQSLAPENVDAFVPQYLKRVEAEENWLK
                     DNEIKDDSHYVKRI"
     gene            18557..19012
                     /gene="rimI"
                     /locus_tag="VCR92_001224"
     CDS             18557..19012
                     /gene="rimI"
                     /locus_tag="VCR92_001224"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEP4268291.1"
                     /translation="MIVTTLSESNMKTVEEQAKNIYQLLEMVYGTSPWTLEQVLIDIR
                     RDQTDYFLLYDHDKLLGFLAIQDLAGEVEMTQIAILPSHQGLGLASQLMTHLDSIESD
                     IFLEVRESNHRAQGLYQKFGFKFIGKRPDYYRNPIETALLMKREGKHDR"
     gene            19002..20030
                     /gene="tsaD"
                     /locus_tag="VCR92_001225"
     CDS             19002..20030
                     /gene="tsaD"
                     /locus_tag="VCR92_001225"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEP4268292.1"
                     /translation="MTDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFEDALQEAGISASDLSAVAVTYGPGLVGALLVGLAAAKAFA
                     WANHLPLIPVNHMAGHLMAAREQKPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSA
                     FINLHHNAKQKGNELILEDLCASFQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQ
                     GLRDRLAQEITHIEVVIPKLRLCGDNAGMIALAAAIEYDKQHFANMSLNAKPSLAFDQ
                     FPDSFVIN"
     gene            complement(20201..20470)
                     /gene="rpsN"
                     /locus_tag="VCR92_001226"
     CDS             complement(20201..20470)
                     /gene="rpsN"
                     /locus_tag="VCR92_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEP4268293.1"
                     /translation="MAKKSKIAKYQKQLQLIEQYADLRRDLKAKGDYESLRKLPRDSN
                     PNRLKNRDKIDGRPHAYMRKFGVSRINFRDLAHKGQLPGVTKASW"
     gene            complement(20691..21449)
                     /locus_tag="VCR92_001227"
     CDS             complement(20691..21449)
                     /locus_tag="VCR92_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP4268294.1"
                     /translation="MSTNDLTKKLKKLKHVQVYNTIFQLIQDGTYSPGMQLPSEPELA
                     RQLNVSRMTLRKSLALLQEDHLIKNIRGKGNFILKTPETKYHQGFEYLQHPIYASLSS
                     DITKVELEYRIEVPTVAITASLKQETPVVIIVDRWYHSQNKAIAYSLSFIPIEVISKY
                     AINLNQEEPLLTFLEEKIYESGKASHSCNQIGYTKTGNYTATKYTLSENSAFILIQET
                     LYNGKDILVSTKHYVPADLFDLKVQSQSCQSDTH"
     gene            21689..22468
                     /gene="udp"
                     /locus_tag="VCR92_001228"
     CDS             21689..22468
                     /gene="udp"
                     /locus_tag="VCR92_001228"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HEP4268295.1"
                     /translation="MQNYSGEVGLQYHLQIRPGDVGRYVIMPGDPKRCAKIAEHFDNA
                     VLVADSREYVTYTGTLNGEKVSVTSTGIGGPSASIAMEELKLCGADTFIRVGTCGGID
                     LDVKGGDIVIATGAIRMEGTSKEYAPIEFPAVADLEVTNALVNAAKKLGYTSHAGVVQ
                     CKDAFYGQHEPERMPVSYELLNKWEAWKRLGTKASEMESAALFVAASHLGVRCGSDFL
                     VVGNQERNALGMDNPMAHDTEAAIQVAVEALRTLIENDKSQ"
     gene            22489..23691
                     /locus_tag="VCR92_001229"
     CDS             22489..23691
                     /locus_tag="VCR92_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HEP4268296.1"
                     /translation="MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIAL
                     ILVRIPLGQQIVSVVSTGVTSVINCGQAGLNFVFGSLADSGAKTGFIFAIQTLGNIVF
                     LSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYL
                     GRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIASTMVPIGSILIAKILLPQ
                     TEPVQKIDDIKMDNKGNNANVIDAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLS
                     GLGIRLEQIFSYVFAPFGFLMGFDHKNILLEGNLLGSKLILNEFVSFQQLGHLIKSLD
                     YRTALVATISLCGFANLSSLGICVSGIAVLCPEKRSTLARLVFRAMIGGIAVSMLSAF
                     IVGIVTLF"
     gene            23721..24392
                     /gene="deoC"
                     /locus_tag="VCR92_001230"
     CDS             23721..24392
                     /gene="deoC"
                     /locus_tag="VCR92_001230"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEP4268297.1"
                     /translation="MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPAS
                     YVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIQNGADEIDMVINLTDVKNG
                     DFDTVEEEIRQIKAACQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFST
                     AGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAKTFIALGASRLGTSRIIKIVKNEAT
                     KTDSY"
     gene            complement(24487..25656)
                     /locus_tag="VCR92_001231"
     CDS             complement(24487..25656)
                     /locus_tag="VCR92_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEP4268298.1"
                     /translation="MTQYDTIIIGGGPAGMMAAISSSYYGYKTLLIEKNRRLGKKLAG
                     TGGGRCNVTNSGNLDDLMAGIPGNGRFLYSVFSQFDNHDIIAFFEENGVKLKEEDHGR
                     MFPTTDKSRTIIDALEKKIKALGGQVLTSTEVVSVKKQDDLFYLKSTDQTFTCQKLIV
                     TTGGKSYPSTGSTGFGHDIARHFKLTVTDLEAAESPLLTDFPHKVLQGISLDDVTLSY
                     DKHVITHDLLFTHFGLSGPAALRLSSFVKGGEIAELDFLPHLSTDDLTAYLSDQRDKN
                     IKNALKGLLPERVADFLSEDYPEKVKQLSPKQEKELLDKLKHLQIPITGKMSLAKSFV
                     TKGGVDLKEINPKTLESKKVPGLYFAGEVLDINAHTGGFNITSALCSGWIAGKSS"
BASE COUNT         8189 a         4299 c         5466 g         7870 t
ORIGIN      
        1 gaatgccata gtcatccgtt gtgataatgc ttgaaaatag tcagttagta agcgaaaaag
       61 tctaacatta acctttataa attgaaaata actgttagta gactaatgac aggtagatac
      121 tcttaatagc gcgtttgatt tcacgcataa aaagctttaa aaacgcttta aattatgata
      181 aaatgaactg tatcgaaatt attttaagga gaaatgactt aatgtctaca tcatttgaaa
      241 acaaagctac aaatcgtggc gtgattacat ttacaattag tcaagataaa ataaaaccag
      301 ctcttgataa agcttttaat aaaatcaaaa aagacttaaa tgcaccaggt ttccgtaaag
      361 gacacatgcc tcgtccagtc ttcaaccaaa aatttggtga agaagttctt tatgaagatg
      421 ctttgaatat tgtattgcca gaagcttatg aagcagctgt gacggaactt ggtcttgatg
      481 tggttgcaca accaaaaatc gatgttgtgt caatggaaaa agggaaagag tggacacttt
      541 ctgctgaagt tgtgacaaaa cctgaagtga aacttggtga ttacaaaaac cttgttgtag
      601 aagttgatgc ttcaaaagaa gtttcagatg aagacgtgga tgctaaaatt gagcgcgaac
      661 gtcaaaacct tgcggaactc attattaaag acggtgaagc agctcaaggt gacactgttg
      721 tgattgactt tgttggttca gttgatggtg ttgagtttga tggcggtaaa ggagataact
      781 tctctcttga acttggttca ggacaattta tcccaggttt tgaagatcaa ctagttggtg
      841 ctaaagctgg cgatgaagta gaagttaatg tcacattccc agaatcttac caagcagaag
      901 atcttgcagg taaagccgct aaatttatga caactattca cgaagtcaaa acaaaagaag
      961 taccagagct tgatgatgag cttgcaaaag atattgatga agatgttgac acacttgaag
     1021 acttaaaagt aaaatatcgt aaagaacttg aagcagctca agaaactgct tatgatgatg
     1081 ctgttgaagg agctgcgatt gaattagcag ttgcaaatgc tgaaattgtt gatttacccg
     1141 aagaaatgat tcatgaagaa gtcaaccgtt cagtgaatga atttatgggc aacatgcaac
     1201 gtcaaggaat ctcacctgaa atgtacttcc aattgactgg tacaactcaa gaagatttac
     1261 ataaccaata ttcagctgaa gctgacaagc gtgttaaaac aaaccttgtt attgaagcaa
     1321 ttgctaaagc agaaggtttt gaagcaacag atagtgaaat tgaacaagaa attaatgacc
     1381 ttgcaacaga atataacatg ccagctgacc aagttcgttc tcttctttca gcagatatgt
     1441 tgaaacatga tattgcaatg aaaaaagcag ttgaagtgat tacaagcaca gcaagcgtta
     1501 agtaatctta ttaaggaaca aaacgtacaa gccggattag aacgtctttc tagtctggtt
     1561 tttctttttc taaagataag gaattagtta aacgttattt taatgaatta gctttaaaga
     1621 tttgtcaaga agaagtgata tgagttgata aaagttttga cgaattactt tttttagcgt
     1681 aaaatggtag agaatgataa aataaggaga actgccttga aattagacgt atttgcagga
     1741 caagaaaaaa gcgagctttc catgattgaa gtggcgcgtg ccattttgga agaacgcggt
     1801 cgcgacaatg agatgtactt tagcgattta gtcaatgaga ttcaaaatta cttaggaaaa
     1861 tctgatgcag gtattcgtca tgcattacca tttttctata ctgacttaaa tacggatggc
     1921 tcatttattc ctctaggtga aaacaaatgg ggacttcgtt cgtggtatgc tattgatgaa
     1981 attgatgaag aaattattac tctagaagaa gatgaagatg gcgcacaaaa acgtaagaaa
     2041 aaacgcgtta atgctttcat ggatggagat gaagacgcta ttgattatag agatgatgat
     2101 ccagaagatg aagatttcac agaagaatca gctgaggttg aatatgatga agaagatcca
     2161 gatgatgaaa aatcagaagt ggagtcatat gattcagaat tgaatgaaat tatccctgaa
     2221 gatgattttg aagaagttga tatcaatgaa gaagacgaag aagatgaaga agatgaagaa
     2281 ccagttctct aatgtcttta gttcagaaat aaaaatgtga ttatcatttg acaaattgtc
     2341 tattatagtt tatattatta ttcgggcacc tctttatgag gtcaggcaaa agctctctag
     2401 ttaatagggg gctatttttg ttttctagaa taatgccagt ttgcctctat atttagaaaa
     2461 ctaaggtgat acctaaccaa tgtggaacca actaataggg aattaacaag aaagcaatgc
     2521 ttttattcag cttatataaa ggagtactat gacgaaatac atttttgtaa ctggtggtgt
     2581 tgtatcatca attggcaaag gaattgttgc ggcaagtctt ggccgattgt taaaaaatcg
     2641 tggacttaag gtgacgattc aaaaatttga tccttatatt aatattgatc cagggacgat
     2701 gagcccctat cagcatggag aagtatatgt gacagatgac ggtgctgaaa ccgacttgga
     2761 tttgggtcac tatgaacgtt ttattgatat caatcttaat aaatattcca atgttacaac
     2821 aggtaaaatt tatagtgaag tccttcgtaa agaacgtaaa ggtgagtacc ttggagcgac
     2881 tgttcaggtg attcctcata tcacagatgc ccttaaagaa aaaatcaaac gcgcagcttc
     2941 aacaacggac tctgatgtaa ttattactga ggtcgggggg actgttggcg atattgaaag
     3001 tttaccgttc ttagaagctc ttcgtcagat gaaagctgat gttggttctg aaaatgtgat
     3061 gtatattcac accaccttgt tgccatattt aaaggcagcg ggtgaaatga aaactaagcc
     3121 aacgcaacat tccgttaaag aattgcgtgg tttagggatt caaccgaata tgttggttat
     3181 tcgtacggaa gagccagttg agcaggggat taaaaataaa ttggctcagt tctgtgatgt
     3241 gaattcagaa gctgttatcg agtcacgtaa tgtagaacac ttgtatcaaa ttccattgaa
     3301 cttgcaagcc caatcaatgg atcagattgt ttgtgatcat ttgaaattga atgcgccaca
     3361 agctgatatg actgagtggt cagctatggt tgacaaggtg atgaatttaa gaaaaacaac
     3421 aaaaattgcc ttggttggta aatatgtgga attgccagat gcctacttat ctgttgtgga
     3481 agccttgaaa cattctggtt atgccaatga taccgcaatt gacctaaaat gggtcaatgc
     3541 taacgatgtg acggtggata atgcagctga cttgttggga gatgcggatg ggattattgt
     3601 accaggtggt tttggtcaac gtggtacaga aggcaagatc caagcgattc gctatgcccg
     3661 cgagaatgat gtgccaatgc ttggtatctg tcttggcatg caactgactt gtgttgaatt
     3721 tgctcgccat gtcctcaata tggaaggtgc aaactctttt gaattagagc caagtactaa
     3781 ataccccatc attgatatca tgcgtgatca aattgatatt gaagatatgg gaggtacgct
     3841 tcgtctggga ttgtacccat gtaaattgaa accaggttca aaagcagcaa tggcttacaa
     3901 taatcaagag gtggtgcaac gtcgtcatcg tcaccgttat gagttcaaca acaaattccg
     3961 tccagaattt gaagcagctg gttttgtttt ctcaggggta tcacctgaca accgcttagt
     4021 tgaaattgta gaattgaaag agaaaaaatt ctttgtagca gctcaatacc acccagaatt
     4081 gcaaagccgt ccaaatcgtc ctgaggagct atacaccgct tttgttacag ctgctattaa
     4141 aaatagcaat tagtggtttt aagggtaagt ttgtggcatt ctacttggct ggcagatact
     4201 gataaagatt actagctatt agagggatct tttctataaa aatagcatta gaaaaagaaa
     4261 aacgtgatat ttttaggtta gcactttctt tttcagtcat ttttttgtaa aatacttggt
     4321 atgaaaacta ttcgaatagc aaagtattta ggaattctat tccttttgat aactcttatt
     4381 agcgtaggtg ctagttttta tttctttcat gttgcacaaa taagagaaga gaaatcgttt
     4441 attaataata agaaacggag tacaaataat ccattatacc cagctgaaca gtcttttgac
     4501 gctttacctt acgaaaaacg tcaactaaca aatcgtgggt taaaacaagt ggggtggtac
     4561 ttaccagctg ctcaaaaaac aaaaaagaca gctattgttg ttcatggttt tacgaatgac
     4621 aaagaagata tgaagccata tgccatgctt tttcatgatt tgggctataa tgtcttaatg
     4681 ccagacaatg aggcccatgg ggaaagtgaa gggaacttga ttggttatgg ctggaatgac
     4741 cgccttaatg tcatggcttg gacagaccaa ctgattaagg aaaaccctga aagccaaatc
     4801 acactctttg gcttatctat gggtgctgca acagtaatga tggcaagtgg tgagcgattg
     4861 cctgcgcaag tcacctccct catcgaagat tgcggttata ccagtgtttg ggacgaattg
     4921 aagtttcagg ccaaggctat gtacaacttg cctgcctttc ctttactcta tgaagtctct
     4981 gccttatcta agattcgagc aggttttagt tacggagaag cgagctcagt gaaacagctg
     5041 gctaaaaata aacgtccaac tttatttatc cacggtgata aggatgattt tgttcctaca
     5101 aaaatggttt atgacaatta taaggccacg aaaggtccta aggaaatctt gattgttaaa
     5161 ggggcaaaac acgccaaatc ctttgaaaca aacccagaac aataccagaa aaaaattgcc
     5221 gcttttttga aaaaagttga gaaataagta ttgacagtta aactcacagt tgctataata
     5281 atttatgtta ctgatgagta gcggggatgg cggaattggc agacgcgcag gactaaggat
     5341 cctgtgaccg ctttaggtcg tgtgggttca agtcccactc tccgcataat gtaagaggtg
     5401 aatcattgat tcgtctcttt tttttggtta aatgaaggat aagaaggcat agatttactg
     5461 gagaaaactt ttgataatct gcttttggaa aacgctttaa gcttgtgaaa gactagaaat
     5521 ttatggaaaa ttgtgctaga atgaacaatg taaacgggga gttatcccga aaaataagag
     5581 gaggccttac aaatggcaat cgtttcagca gaaaaatttg tccaagcagc tcgtgaaaac
     5641 ggatatgctg ttggtggatt taacacaaac aacttagagt ggactcaagc aatcttgcgt
     5701 gcagcagaag ctaaacaagc tccagttctt atccaaacat caatgggtgc agcaaaatac
     5761 atgggtggtt ataaagtatg tcaatctctt attactaacc ttgttgagtc aatgggtatc
     5821 actgttcctg ttgctatcca ccttgatcat ggtcactacg aagatgctct tgagtgtatc
     5881 gaagtaggtt acacttcaat catgtttgac ggttcacacc ttccagttga agaaaacctt
     5941 gctaaaactg cagaagttgt taaaattgca catgctaaag gcgtttcagt tgaagctgaa
     6001 gttggtacaa tcggtggtga agaagacggt atcatcggta aaggtgagct cgctccaatc
     6061 gaagatgcta aagcaatggt tgaaactgga attgacttct tggcagctgg tatcggtaac
     6121 atccacggtc catacccaga aaactgggaa ggtcttgctc ttgaccactt agaaaaatta
     6181 acagcagctg taccaggttt cccaatcgta ttgcacggtg gttctggtat tcctgacgat
     6241 caaatcaaag aagcaatccg tcttggtgtt gctaaagtta acgttaacac tgaaagtcaa
     6301 atcgctttct ctaacgcaac tcgtgaattt gctcgtaact acgaagctaa cgaagcagaa
     6361 tatgatggta aaaaattatt tgacccacgt aaattcttgg ctccaggtat gaaagctgtt
     6421 caaggtgctg ttgaagaacg tatcgatgtt ttcggatcag ctaacaaagc ataatttaga
     6481 gtattaaata ccctaaagcc ctcttgaggg cttttttaga tacaattgac accctaaaat
     6541 ggataccagt ttctgtgaaa caatctttga ttgtgaacaa acaaagcata atttagagta
     6601 ttaaaatctg gaccctgcta tctatggtaa gtctttttgt tattgttaaa gaggttaagc
     6661 ggaatgttaa tatgttttag ctaaaaaatg tagtgaaaaa tgagtacgta gactattgta
     6721 atagtaattc cgtaaaattg ttgaaaaaga aaatgggaaa taccttgtca aattaagcac
     6781 cctatgatag aatagatagg tatgtggtgc tagcacatcc gtaaacatat tctacgtagg
     6841 aggaaacaga tcaaaatggc taaagtatgt tattttacag gacgtaaaac cgtttctgga
     6901 aacaaccgtt cacacgcgat gaaccaaacg aaacgtacag ttaaaccaaa ccttcaaaaa
     6961 gttacgatcc ttgttgatgg taaacctaaa aaagtttggg cttctgctcg tgcgcttaaa
     7021 tctggtaaag tagaacgcat ctaatagaaa taagccttag ggcttttttt attagcttat
     7081 ttctatccat aagctagtca gggtaataaa cgctatcgtt aactattcta tctcttttac
     7141 attacttcta aaatatgata aaataggatg ataaaaactt tttgaggtag taactatgac
     7201 tgtaaaaatt aatacaaaag atggtctaat cgagctatcc gacgatgtga ttgcaactgt
     7261 cgtgggagga tcagcaacgg aaatttttgg tgttgttgga atggccagca aaagtgcaat
     7321 aaaagacaat tttcaatcac tacttcgcaa agaaaactac gctaagggtg ttgtagtaaa
     7381 atcaacagat ctgggtattt ctgttgatgt ctacactgtg atgagttatg gtgtgaaaat
     7441 cagtgaagtc tctaaaaata tccaagaacg cgtgaaattt aaccttgaaa gtcagcttgg
     7501 tctcactgct gatatggtca atgtttacgt gcaaaatatt aaggttgtag gagaaaatta
     7561 gtgtcaaata ttacaacaag cttattccaa gaaatggtcc aagcggcagc gactcgcctt
     7621 ggcaaacaag cagaatatgt taattcctta aatgtttttc ctgttccaga tggtgataca
     7681 ggaacaaaca tgagtatgac tatggacaat ggtgccaagg aagttgctga taaacctgcg
     7741 tcaactgtgg gagaagttgg acaaatgtta tcaaaaggtc ttttgatggg agcgcgtgga
     7801 aattctggag ttattacttc acaacttttt cgtggttttg gtcaaagtat taagggaaaa
     7861 gatgagctga caggtaaaga tttggcacaa gcctttcaag tgggtgtaga agttgcctac
     7921 aaagcagtga tgaaacctgt tgaagggaca atcttgacag tatctcgtgg agcagcaacc
     7981 gctgccttaa aaaaagcgga tcttacagac gacgccgtgg aagtcatgca agctgcttta
     8041 gacggtgcca aaggtgccct tgctaagaca cctgatttat taccagtcct taaagaagtt
     8101 ggtgtggttg attcaggcgg tcaaggtctt gtctttatct atgaaggttt cctatctgct
     8161 ttgaatggcg actatgtgac ttcagcagac tttaaagcga ctcctgctaa catgtctgaa
     8221 atgattaatg ctgagcatca caaatccgtt gttggtcatg tggctactga agacattacc
     8281 tacggttatt gtactgaaat catggttgcc cttaaacaag gcccaaccta tgtgaaagaa
     8341 ttcaactatg atgagtttca aggctacctt agtggccttg gtgactcgct gttagtggtc
     8401 aatgatgatg agattgttaa agttcacgtc catactgaag accccggact tgtgatgcaa
     8461 gaaggtctta aatatggttc gctcatcaag attaaagtgg acaatatgcg taaccagcat
     8521 gaagcacagg ttcaaaagac tgatgtcgaa aaaaacaagg ctgaagtaaa agaatttggc
     8581 ttgattgcag tagtagctgg agaaggttta tctgaaattt tcaaggcgca aggtgttgat
     8641 tacgtgattt ctggtggtca aaccatgaat ccatctacag aagatattgt taaagctatt
     8701 gaagcagtta atgccaaaca agtcattatc ttgccaaaca ataaaaatat ctttatggct
     8761 gcccaatctg ctgcagaagt ggtggatatc ccggctgctg ttgttgcaac acgtactgtt
     8821 ccgcaaggat ttaccagctt gttggccttt gatccttcaa aatctttaga ggacaatgta
     8881 gcagatatgt caactagtct ttctgacgtg gtcagtggaa gcgttacttt ggcagtccgt
     8941 gacaccacca ttgatggttt agaaatccat gaaaatgatt tcttgggaat ggttgatggt
     9001 aaaatcatcg tttcaaaccc agacatggaa gcaactctaa aagctgcctt tgaaaagatg
     9061 attgacgaag atagcgagat tgtgactatc tttgttggtg aagaaggtga tcaagactta
     9121 gcagaagaac ttgctgggta tttaggagag acttacgaag atgtggaagt tgagatccat
     9181 caaggagatc agcctgttta cccatatctc atgagtgtag aataatagaa tacaataaaa
     9241 aaagaggagt taggcaaagg tctgactctt tttgtctata ttgatgtcgt aatgagtggt
     9301 tttagtgatg gtaagcccct aaaaaatgag ggtaatccat cacaaagcta atggttacga
     9361 tttagtttga caaaacctag aaaaacatta taattgtatt ataacaataa gtcaagaact
     9421 gaaaacggtt cagttctaag atatgacaag gaggagattt tatgttagga ccatttatct
     9481 ttattgcttt tggggttatt gtaatcctag ctattgttgc cagtaccctt tatgttgttc
     9541 gtcaacaatc tgttgccatc gtggaacgtt ttggtaggta ccaaaaaaca gccacgagtg
     9601 gtattcatgt ccgccttccg tttgggattg acaaaattgc tgcgcgtgtg cagctgcgtc
     9661 ttttacagtc agaaatcatc gttgaaacca aaaccaagga caatgtgttt gtaactttga
     9721 atgttgccac tcagtatcgt gttaacgaac aaaatgtaac agatgcttac tacaaattaa
     9781 tgaaacctga atctcaaatc aagtcttata ttgaagatgc cttgcggtca tccgtgccga
     9841 agttgacctt agacgaattg tttgagaaaa aagatgaaat tgccttggaa gtacaacatc
     9901 aagtggcaga agaaatgtca acctatggat atattattgt caaaaccttg attaccaagg
     9961 tggagcctga tgctgaagtc aaacagtcaa tgaatgaaat caatgcggct caacgcaaac
    10021 gtgtagctgc tcaagagttg gcaaacgcag ataaaattaa aattgtgaca gcagcagaag
    10081 cagaggctga aaaagatcga ttgcacgggg tagggattgc ccaacagcgt aaggccattg
    10141 tggatggttt ggcggagtct attcaagagc ttaaagaagc gaatatttcc ttaaacgaag
    10201 aacaaatcat gtccattttg ttgaccaacc aatacctgga taccctcaat acctttgcga
    10261 caaaaggaaa ccaaaccctt tttctaccaa atacaccaag tggggtagag gatatccgta
    10321 cacaagtttt atctgccctt aaaacaaaat aacgtgtaaa agcttggcta aaaagttgct
    10381 caatactgga tttagcagaa ggctatcata ccttgtgaag tggcaaacga cgaaatgaat
    10441 acattacttt tattggagaa atgaaagtaa aaaaagcctt tttcatgatt aacaacatag
    10501 tattgattaa atgttaagtt gtattgactt ttaaattaaa taagtttaaa atcaacttaa
    10561 taagcaaaaa ggagattttc aatgaaatcc aaaaaagttg ttagtgttat atcacttacc
    10621 ttatcccttt ttttggtgat aggttgtgct aaagttgata acaacaaatc agttaattgt
    10681 aagcctgcta ctaaacaaac ctataatagc tatagtgatg accaattaag atcgcgtgaa
    10741 aataccatgt ctgttttatg gtaccagcga gctgcggaaa ctcaagcgct ttatttacag
    10801 gggtatcagt tagcaacgga tcgcttaaaa gaacaactca ataaaccaac ggataaacct
    10861 tattcaattg tattagatat tgacgaaaca gttcttgata atagccctta tcaagctaaa
    10921 aatgttttgg aaggaacagg atttacacct gaaagctggg attattgggt acaaaagaaa
    10981 gaagcaaaac cggttgctgg tgctaaagac tttttgcaat ttgcagacca aaatggtgtt
    11041 caaatttact acatttcaga cagatcaact actcaagtag atgctacaat ggaaaatctc
    11101 caaaaagaag gtattccagt acaaggtcgt gatcatcttc tattcttaga aaaaggcgta
    11161 aaatcaaagg agagtcgtcg tcaaaaggtc aaagaaacaa ctaatgtaac gatgctattt
    11221 ggtgataatc ttctagattt tgctgatttt tcaaaaaaat ctcaagaaga tagaacagct
    11281 ttattatcag atttgcaaga agagtttgga agacgcttta tcattttccc taatcctatg
    11341 tatggttcat gggaaggtgc catttataaa ggtgaaaagc tggatgtgct taagcaacta
    11401 gaggaacgcc gtaaaagttt aaaaagcttt aaataaagta attgaaaaag aggtgcaaaa
    11461 gaaaatgtaa cctcttttta agtactatta ttttctgaaa atagggttaa tgactgaaaa
    11521 aaatgttgat tttgtgaaat gattatttta ttattttcat attttatctt tatgctagga
    11581 attgtggtat aatggaggag tataaaaaat attaaggagt ctattcacat ggctaaattg
    11641 actgttaaag acgttgattt gaaaggtaaa aaagtcctcg ttcgtgttga ctttaatgtg
    11701 cctttgaaag atggcgttat cactaacgac aaccgtatca ctgcggctct tccaacaatc
    11761 aagtatatca tcgaacaagg tggtcgtgct atcctcttct ctcaccttgg acgtgttaaa
    11821 gaagaagctg acaaagaagg aaaatcactt gcaccggtag ctgctgattt agctgctaaa
    11881 cttggtcaag atgttgtatt cccaggtgtt actcgtggtt caaaattaga agaagcaatc
    11941 aatgctttgg aagatggaca agttcttttg gttgaaaaca ctcgttttga agatgttgac
    12001 ggtaagaaag aatctaagaa tgacgaagaa cttggtaaat actgggcttc acttggagat
    12061 ggaatcttcg ttaacgatgc atttggtaca gcacaccgtg ctcacgcatc aaacgtaggt
    12121 atttcagcaa acgttgaaaa agctgtagct ggtttccttc ttgaaaacga aattgcttac
    12181 atccaagaag cagttgaaac tccagaacgt ccattcgtag ctattcttgg tggctcaaaa
    12241 gtttctgata agattggtgt tatcgaaaat cttcttgaaa aagctgataa agttcttatc
    12301 ggtggtggta tgacttacac attctacaaa gctcaaggta tcgaaatcgg taactcactt
    12361 gtagaagaag acaaattgga tgttgctaaa gacctccttg aaaaatcaaa tggtaaattg
    12421 atcttgccag ttgactcgaa agaagcaaac gcatttgctg gttacactga agttcgcgac
    12481 actgaaggtg aagcagtttc agaaggcttc cttggtcttg acatcggtcc taaatcaatc
    12541 gctaaatttg atgaagcact tactggtgct aaaacagttg tttggaacgg acctatgggt
    12601 gtctttgaaa accctgactt ccaagctggt acaatcggtg tcatggacgc tatcgttaaa
    12661 caaccaggcg ttaaatccat catcggtggt ggtgattcag cagcagctgc tatcaacctt
    12721 ggccgtgctg acaaattctc atggatcagt accggcggag gcgctagcat ggaacttctc
    12781 gagggtaaag tattaccagg tttggcagca ttgactgaaa aataatagtc attataatat
    12841 atagtaaagg gcatgctgat gcatgtcttt ttttagttga tcatgtacag ttattgaact
    12901 ttccctaact tcacttatca tttactagtt tttagatata gtggtatttg gctgacactg
    12961 caattttcaa aagtttatga cgatttcata tcaattggtt tataaaagat atcctaatca
    13021 taaataaaac gtttaccaaa agggttttat ggattgatat gttaaaatag atagtgaagg
    13081 gataggtatg aaaacgttaa gaaaattatt atctaattac aagtttgata ttaaaaagtt
    13141 taaattggga atgagaacat tgaaaacagg cttatcggtc tttttagttt tattggtttt
    13201 tcatttattt ggttggaaag ggcttcaaat tggtgctcta actgctgtat ttagtttaag
    13261 agaagacttt gataaaagcg tgcactttgg cttttctaga attattggta atagtatagg
    13321 tggcctactc tccttagtat tttttgcatt caatgagata tttcatcaag ctttttgggt
    13381 tactttatta attgttccta tttgtaccat gttatgtatc atggttaatg ttgcatgtaa
    13441 taataaatca ggtattattg gggcagtggc tgctcttttg attattacac tgtctattcc
    13501 aacaggacaa acgtttattt atgtgacttc gcgggtattt gaaacatttt gtggcgtctt
    13561 tgtagctatt ttagttaata ctgatgttga acttattaaa aataaatggt ttaacaaaaa
    13621 acacagtgat gttagataat ataacatata tacttgacag gttatttttt tcagcctata
    13681 ataaggaaga tgaaaggagt ttgtcatgaa agaaaaagaa cttagacgct caatggctgt
    13741 ttttcctatt ggaacggtga tgacattaac agatctctct gcgagacaaa ttcgctatta
    13801 tgaagatcaa ggtttaatta agcctgaacg aacgcaaggg aatcggcgta tgttttcctt
    13861 aaatgacatg gaccgacttt tggaaattaa agattttttg tctgagggat taaatattgc
    13921 agctattaaa cgcgaatatg tcgagcgtca aggtaagtta atgcaaaaac aaaaagctct
    13981 aacagatgca gatgtcagac ggatcttaca tgatgaaatg ctgacacaaa gcggtttttc
    14041 tactccctca cagcatattg gtaattttcg tatttaagat atgaattgta taaaatttaa
    14101 aggagaccta tttaatggca atcacagtag ctgacattcg tcatgaagtc aaagaaaaaa
    14161 atgtaacgtt tcttcgcttg atgttcactg atatcatggg cgttatgaaa aatgtggaga
    14221 ttcctgcaac gaaagaacag ttagacaaag tattgtctaa caaggttatg tttgatggtt
    14281 catctatcga aggttttgta cggatcaatg agtcagatat gtacctttac cccgatttag
    14341 acacttggat tgtttttccc tggggagatg aaaatggagc agttgcaggt ttaatttgtg
    14401 atatttatac agcagaagga aagccttttg caggagatcc tagaggaaat ttaaaaagag
    14461 ccctgaaaca catgaacgag atcggctaca aatcatttaa tcttgggcca gaaccagaat
    14521 ttttcctttt taagatggat gataaaggta atccgacact tgaagttaac gataatggtg
    14581 gttattttga tttagcgcca attgacttag cagacaacac gcgccgtgaa attgtgaata
    14641 ttttaacgaa aatgggtttt gaagtggaag ctagtcatca tgaagtggct gttggtcaac
    14701 atgagattga ttttaaatat gcagatgttt tgaaagcttg tgataatatt caaattttta
    14761 agctagttgt aaaaacgatt gcccgtgaac atggacttta tgctactttt atggctaaac
    14821 caaaatttgg aatagctgga tcagggatgc actgtaacat gtctttgttt gataaccaag
    14881 gtaataatgc tttttatgat gaaactgata agcgaggaat gcagctatca gaagatgctt
    14941 attatttctt gggaggacta atgaagcatg cttataacta cactgctatc actaacccta
    15001 cagtgaattc ttacaaacga ttagttccgg gttatgaggc acctgtttat gtcgcttggg
    15061 ctggaagtaa tcgttcaccg cttatccgtg ttccagcatc acgtggtatg ggaacgcgtt
    15121 tggagttacg ttcggttgat ccgacagcta atccttattt agccttggct gttctcttgg
    15181 aagctggatt agatggtatc attaacaaaa ttgaagctcc agaacccatt gaagctaaca
    15241 tttataccat gacaatggaa gaacgaaatg aagcaggcat tattgatttg ccatcaacgc
    15301 ttcataatgc cttaaaagct cttcaaaaag atgatgtggt acaaaaggca ctaggttacc
    15361 atatctacac taatttctta gaagcaaaac gaattgaatg gtcttcctat gcaactttta
    15421 tttctcaatg ggaaattgac cattatattc ataattatta gacttatcag gacctgctca
    15481 agttgagtgg gtcttttgga tgagctattg tatttgagct agcaagctat tattagctga
    15541 tcggacacca attgattttc cattatagaa aactaaaaac cagtccatgt tctatgagga
    15601 ctggttttta gtttgataat tatctgaact agaactgata tgttaaagat atagacagat
    15661 agtattaaga aatgagtctt atttgatttt agtgcttatc aggtgttaag accatcggaa
    15721 ttataattgg ttcacgctca gtcttttcat acaagaatgg acgaagagca ttgacgatag
    15781 caccgttaac tgattggatg ctagcatcct tattttttaa agcaatacgg atagcgttaa
    15841 agagcacacg ttggctttcg cggatcaagt cacctgactc acgcatataa atgaaaccac
    15901 ggctcagaat atctggtcca gctaaaatca tttgtgtgtt aaaatcaaca gttgcaacag
    15961 ctaagacaac accatcttct gacaaatcac ggcggtctcg taaaacggct gctccaatat
    16021 ccccgatgcc attaccatcc acgtagatgt cttgggcatt aaagtgacca gcaatacgcg
    16081 cactgtcact ggttaaagct agaacgtctc cattttccat aataaagata ttttcttttg
    16141 gaataccaat atccatcgcc agtcctgcat gaactttttg catgcgatac tcaccatgta
    16201 ctggcatgaa atattttggt ttaatcaaac taagcatgag cttttgttct tgctgtcctc
    16261 catgaccaga agtatgaata ttattgactt ttccatgaat aacatcaaca ccagcttctt
    16321 ggatggtatt gattaattta ttgacacttg tggtattacc agggattgga cttgatgaga
    16381 aaatcacagt atcaccaggc tgtaaagtta cttgacgatg agtgccatta gcgatacgag
    16441 caagtgctgc catagactca ccttgactac ctgtacacat aattaaaact tcactagcat
    16501 gaagattttt aagttcgctt ggctcaatga aggtaccatt tggaacttta atatagccaa
    16561 gttcaatacc gttaacaatt gctttttcca tagaacgacc aaaaacggca attttacgtc
    16621 ccgttttaac agcagcttct gcagcctgtt gcaaacggta gatgtttgaa gcgaaggaag
    16681 caaaaataat acgaccatga ataccttcga taatttttaa aatggattgg ccaacaactt
    16741 tttcagagtt agtaaaggtt gggatttcag cattagttga gtctgataat aagcaaagga
    16801 caccttcttc accaagcgct gccatacgtt gtaaatctgc aggatctcct actggcgtga
    16861 agtcaaattt aaaatcacca gtacagataa tcttaccttg aggggtgtgg ataacaatac
    16921 cgaccggttc tggaatggaa tgagtagtct tgaagaaagt gacgctcatg tttttaaaag
    16981 ttaactcggt gttgtgattg atttcgtaaa cagttgcttc acgccaaaga ccatgttctt
    17041 ccaatttacc acggataaga gcaagtgcta aaggtcctgc gtagataggg atattagcct
    17101 gtttgagaag aaatggaata ccaccaatgt ggtcttcgtg accatgtgta ataacaagag
    17161 cttttacccg gtctaagtta tcgacaatgt aagaatagtc tggaataacg taatcaattc
    17221 ccaaaagatc atcttctggg aatttgatac cggcatcaac gataatgatc tcgtcttgat
    17281 actcaatacc ataagtattc ttcccaatct ctcccagacc accaatggca aacaccccaa
    17341 cttcattagg ttttaaactg atatttgtca tcttagaact ccgttaattc aaaaacaccg
    17401 gtctcttttt cgtaatcgag gtgtttgtca gaaagtagct cgataaattc cacgttataa
    17461 taggtgttat cttcaacgag acgacgagcc ttgatacggc catcgagttc atcagtagca
    17521 tcaatattaa gatagagtgc tttagtactt tcacgacgtg ggctttgatc ctttgtttct
    17581 tgatagaaaa ctttataaat catttgtttt ttattccttt cgttatgaat caattatcca
    17641 aacaataata aataggtcaa aaggtaggtg ttccattttg acggttttat atgttgtcat
    17701 tattgtgtag tagattaatt cctgattctg tgcaattatt ataattatac cataaactta
    17761 gcttttagta aaaaatttag gtacatttat ggtatagtct aaatcaaatt aagagtcagc
    17821 ctttttgttt atgattctta atttgtgtta taattgatac tagaacttgc agtagaaagg
    17881 cataaaatga agacacttgc atttgatacc tcaaataaaa ccttgtccct tgctatactt
    17941 gatgatgaga cacttctagc agatatgacc cttaacattc agaaaaatca tagtgttagc
    18001 cttatgcctg ctattgattt tttgatgact tgtactgatc ttaaacctca agatttagaa
    18061 agaatagtgg ttgcaaaagg ccctggatct tacacaggtt tacgagtggc agttgctact
    18121 gcaaaaacgt tagcgtacag tttaaatatt gcattggtcg ggatttccag tctatatgct
    18181 ttggctgcgt ctacttgtaa acagtatcca aatactttgg tggtgccatt gattgatgct
    18241 agaaggcaaa atgcgtatgt aggttattat cggcaaggaa aatcagtgat gccacaagcc
    18301 catgctccac tagaagttat tatagaacaa ttagtagaag aagggcagct gatttttgtt
    18361 ggggagactg ctccttttgc tgagcaaatt caaaagaaac tacctcaggc gatactactt
    18421 ccaaccctgc cttctgctta cgaatgtggt cttttggggc aaagtttggc accagaaaat
    18481 gtagacgcct ttgtccctca atatctcaag agagtggaag ctgaagaaaa ctggctcaaa
    18541 gataatgaga taaaagatga tagtcactac gttaagcgaa tctaatatga aaacagttga
    18601 agaacaagca aaaaatattt atcagctttt ggaaatggtt tatggcacgt ctccttggac
    18661 tttagaacaa gtattaatcg atatacggcg ggatcaaaca gattatttcc tactatatga
    18721 tcatgataaa ttgctaggtt ttttagctat tcaagattta gctggtgaag ttgaaatgac
    18781 tcaaattgct atactaccta gtcatcaagg acttgggcta gcgtctcaat tgatgacgca
    18841 tttagatagc attgaaagtg acatcttttt agaggttaga gaatctaatc atagagcaca
    18901 gggtttatat cagaagtttg gttttaaatt tattggcaaa agaccagact actatagaaa
    18961 tcctatagaa acagctttat tgatgaaacg ggaaggaaaa catgacagat aggtatattt
    19021 tagcagttga gagttcttgt gatgagacca gtgtagcgat tttaaaaaac gaaagtaccc
    19081 tcttaagtaa tgtcattgca agtcaggttg agagccacaa acgctttggt ggtgtggtgc
    19141 cagaagtagc tagtagacac catgtcgaag tgattacgac ttgctttgag gatgctttgc
    19201 aagaagctgg catcagtgct tcagatttat cagcagttgc ggtaacttat ggccctggac
    19261 ttgttggagc cttgttagtt ggattagcag ctgcgaaggc ttttgcttgg gcaaatcatt
    19321 tacctttgat tccggttaat catatggcag gtcacttaat ggcagcgcgt gaacaaaagc
    19381 ctttagttta tcctttaata gcactattgg tttcaggagg acacacagaa ttggtttatg
    19441 tcccagagcc aggggattat catattattg gcgagacgcg tgacgacgct gttggtgagg
    19501 cttatgataa agttgggcgt gtgatgggct taacctatcc ggcaggacgt gaaattgatc
    19561 agttggctca taaaggtcaa gatacttatc atttccctcg tgctatgata acagaagacc
    19621 acttagaatt ttctttttca ggactcaagt ccgcttttat caatcttcat cataatgcta
    19681 agcaaaaagg caatgaactg attctagaag atttgtgtgc atcttttcaa gcagctgttc
    19741 tagatatttt attggccaaa acaaaaaaag ctctgagcag ataccctgca aagatgcttg
    19801 tagtggctgg tggtgtagcg gcaaatcaag gattacgaga tagattagca caagaaatta
    19861 cacatataga agttgtgatt cctaaactaa gactctgtgg agataacgcg ggtatgattg
    19921 ctttagcagc agctattgag tatgacaaac agcattttgc taatatgagc ctaaacgcga
    19981 agcctagttt agcttttgac cagtttccag acagttttgt aataaactag tcacacttgc
    20041 tagttagtaa gatttataat ggataagaat ctccctttga aaaaacaacc cggtatcttg
    20101 gcataccggg ttgtcatgat gataagtaat tggcttctat ggttactaat aattcagata
    20161 attacctgca aaataattgt ctgcctaagg tgaagtaagc ttaccagcta gctttagtga
    20221 cgccaggaag ctgtcctttg tgagctaagt cacggaaatt gatacggcta acaccaaact
    20281 tacgcatgta agcatgagga cggccgtcaa ttttgtcgcg gttcttcaag cggtttggat
    20341 ttgaatcacg aggcaatttg cgcagtgatt cataatcgcc cttcgctttt aagtcacgac
    20401 gaaggtcagc gtactgttca atcagttgga gctgcttttg gtatttagca atttttgact
    20461 tttttgccat tgctttctcc ttcttaatat ttaataacct cagagtcgtt atcagcgctc
    20521 tgaatccact taactggtat ttaactggtt aagtggatat ataatcatta tacaataaat
    20581 aaaagcaaaa gcaaataaaa aaaattaact agttatcttt tttagccata atatcaaaaa
    20641 actccacatc taagtgtggg agtcaggtat taataactgt ttaaaggtgt ttaatgagtg
    20701 tcgctttggc aactttgaga ttgaactttt aagtcaaata aatcagcagg aacgtagtgt
    20761 ttggttgaga ccaagatgtc tttaccattg tagagagttt cttggattaa aataaaagca
    20821 ctattttctg atagagtata cttagttgct gtgtaattgc cagtcttggt atagccgatt
    20881 tgattgcagg aatgagaagc tttaccagat tcatagattt tctcttctaa gaaagtaaga
    20941 aggggctctt cttgattgag atttatagca tatttagaaa taacttcaat agggataaaa
    21001 gataaactat aagcaatagc tttattttgg ctatgatacc agcgatcaac aataatcaca
    21061 acaggagttt cttgttttag ggatgctgta atggcaacag tgggcacttc aatccgatat
    21121 tccaattcaa cctttgtgat gtcagatgat aggcttgcat atatggggtg ttgaagatat
    21181 tcgaaacctt ggtgatattt agtttcagga gtcttgagta taaaatttcc ctttcctctg
    21241 atatttttta tgagatgatc ctcttggagg agggctaggg atttacgcag tgtcatccga
    21301 ctgacattga gctgtctagc aagttcaggt tctgatggca gttgcatgcc aggactatat
    21361 gtaccatctt gaataagttg aaaaatagta ttatatactt gcacatgttt aagttttttg
    21421 agttttttgg ttaagtcgtt agtagacata tcacttacct cattaataat ctttagtgga
    21481 gtttaacttg tctaaaaact attttagcac taacagtatt ccttgattag aattgtaccc
    21541 atctatagtg ttagtatctc acactcaggt actttttgtc aaaaaagaga tgaaaaacac
    21601 cttaaaaaag cgtttacaaa atagagtgtg tgtgatacta tacaagtgta tcaaaaatta
    21661 gacaagtaaa atacaggagg tttttaacat gcaaaattat tcaggtgaag tcggattgca
    21721 atatcaccta cagattcgtc caggtgatgt aggtcgttat gttatcatgc caggtgatcc
    21781 aaaacgttgt gcaaaaattg cagaacattt tgataatgca gttcttgtag cagacagccg
    21841 tgaatatgtt acgtatacag gtacattaaa cggtgaaaaa gttagtgtta cttcaactgg
    21901 tattggtggt ccatcagcgt ctattgcgat ggaagaattg aaactctgtg gcgctgatac
    21961 ctttatccgt gttggaacat gtggtggtat tgaccttgat gttaaaggcg gagacatcgt
    22021 tattgcaact ggagctatcc gtatggaagg gaccagtaaa gaatatgctc cgattgaatt
    22081 tcctgctgta gctgacttgg aagtgacaaa tgctctagtt aatgcagcta aaaagcttgg
    22141 ttatacaagt cacgcaggag tagttcaatg taaagatgca ttttacgggc aacatgagcc
    22201 agaacgtatg ccagttagtt atgaattatt aaataaatgg gaagcatgga aacgtctggg
    22261 aacaaaagcg tctgaaatgg aatctgcagc tctttttgta gcagcaagtc atctaggagt
    22321 tcgttgtgga tcagatttcc ttgttgttgg taatcaagaa cgcaacgctt tgggtatgga
    22381 taacccaatg gctcatgata cagaagcagc tattcaagtt gctgttgaag cactccgcac
    22441 acttattgaa aatgataaat cacaataagc gaggttttgg aagtcatcat gcaatttatt
    22501 tatagtatta ttggtatttt attggtatta ggaattgtgt atgcaatttc tttcaatcgt
    22561 aagagtgttt ctctaagttt aattggaaaa gctcttatcg ttcaattcat tattgcgcta
    22621 atcttagtac gtatcccact aggccaacaa attgttagtg ttgtttcaac tggagttact
    22681 agcgtaatca actgtggtca agctggttta aattttgtgt ttgggtcatt agcagatagt
    22741 ggcgcaaaaa ctggttttat tttcgctatt caaacgcttg gtaatattgt tttcttatct
    22801 gccctagtta gtctacttta ttatgtagga atccttggat ttgtagtaaa atggataggt
    22861 aagggcgttg gtaaaattat gaaatcctca gaggttgaga gttttgttgc cgtagctaat
    22921 atgtttcttg gtcaaacaga cagtccaatt ttggttagca aatacctagg tcgtatgact
    22981 gatagtgaga taatggttgt gttggtatca ggtatgggaa gtatgtcagt ttctattctt
    23041 ggtggctata ttgcattagg cattccaatg gaatatctct tgattgcttc aacaatggtt
    23101 cctattggca gtattctcat tgctaaaatc ttattgcctc aaacagaacc tgttcaaaaa
    23161 attgatgaca ttaagatgga taataaaggt aataacgcca atgtgattga tgcaatcgct
    23221 gagggtgcaa gcacaggtgc acaaatggct ttctcaattg gggctagttt gattgccttt
    23281 gttggtttag tttctttgat taatatgatg ttaagtggat tgggaattcg cttagaacaa
    23341 atcttctcat atgtttttgc tccatttggt tttcttatgg gatttgacca caaaaacatt
    23401 cttctagaag gaaaccttct tggaagtaag ttgattttaa atgagtttgt ttcgttccaa
    23461 caattgggtc acctaatcaa atctttagat tatcgtacag cattggtagc aactatttca
    23521 ctctgtggtt ttgctaattt atcaagttta ggtatttgtg tttcaggtat tgctgttctt
    23581 tgcccggaga aacgtagcac cctagctcga cttgttttcc gtgcaatgat tggtggtatt
    23641 gctgtaagta tgcttagcgc ctttatcgtc ggtattgtaa ctctattcta aacgttgaca
    23701 aaagaaagaa ggatagtaac gtggaagtaa aagatatttt aaaaacggta gaccatactt
    23761 tgctagcaac aacagcaacg tggccagaaa tccaaacaat tttagatgat gccatggctt
    23821 atgaaacagc ttcagcatgt attccagctt cttacgtcaa aaaagcagca gaatacgttt
    23881 caggtaaatt agctatttgt actgttattg ggttcccaaa tggctatagt acaactgcag
    23941 cgaaggtttt tgaatgtcaa gatgctattc aaaatggtgc tgatgaaatt gacatggtca
    24001 ttaatttgac agacgttaaa aatggggatt ttgatactgt tgaagaagaa attcgtcaaa
    24061 tcaaagccgc atgtcaagac catatcttaa aagttatcgt tgagacatgt caattaacta
    24121 aagaagaact tatcgaactt tgtggagttg tcacacgttc aggtgcagac tttattaaaa
    24181 cctctactgg tttttcgaca gcaggtgcta catttgaaga tgttgaagtg atggcaaaat
    24241 atgtcggcga aggtgttaaa attaaggcag caggtggaat ctcatcattg gaagatgcta
    24301 aaacatttat tgctttagga gcttcacgct tgggtactag ccgtatcatc aagattgtta
    24361 agaacgaagc tacaaaaacc gatagctatt aacttaatca taccgattta gcttgagact
    24421 aaaacaaaaa actcatataa taggagttaa aaagcctact atcttagtga taataggctt
    24481 ttttagctat gaagacttcc ctgcgatcca tcctgaacaa agagctgagg taatattaaa
    24541 ccctccggtg tgagcattaa tatctaagac ctctccagcg aaatacaggc caggaacttt
    24601 cttgctttcc aaggttttag ggttgatttc ttttaaatct acgcctcctt tggtcacaaa
    24661 tgatttagcc aaagacattt ttcctgtaat gggtatctgg aggtgtttga gtttatcaag
    24721 caattccttt tcttgttttg gagagagttg tttgaccttt tcggggtaat cttctgataa
    24781 aaaatcagct actcgttcag gcagtaggcc tttaagagca tttttgatgt ttttatcacg
    24841 ttgatcactc agataagcgg ttaagtcatc tgttgataag tgtggcaaaa agtccagctc
    24901 tgcaatttct ccacctttca caaaagagga cagacgaaga gctgcaggtc ctgaaaggcc
    24961 aaagtgggtg aagagtaagt cgtgtgtgat gacgtgtttg tcataactaa gagtaacgtc
    25021 gtctagggaa ataccttgca agactttgtg aggaaaatca gttaacagag ggctctcagc
    25081 agcttctaaa tcagtcacgg tcagtttaaa atgccgtgca atatcatgtc caaaacctgt
    25141 tgaacccgtt gaagggtagg acttgcctcc tgtggtcaca atcaattttt ggcaggtgaa
    25201 agtctggtct gtagatttga ggtagaagag gtcatcttgt tttttaacgg aaaccacttc
    25261 agtgctggtt agcacctgac ccccaagagc cttgattttt ttctccagag catcaatgat
    25321 tgtccttgat ttatctgttg tggggaacat ccgtccatgg tcttcttctt tgagtttgac
    25381 gccgttttcc tcgaaaaagg caatgatgtc atggttgtca aactgggaaa aaacactata
    25441 taaaaagcgg ccattcccag gaatgcctgc cataaggtca tcaaggttac cactattagt
    25501 gacattacag cgtccaccac cggttcccgc taatttttta cctaagcggc gatttttttc
    25561 aattaagaga gttttatagc catagtagct gctggagatg gcggccatca taccagcagg
    25621 gccacctcca ataataatcg tatcgtattg agtcatagcc ttattttagc ataaaagcgg
    25681 ggggtttaat agtcaggtaa atgaactaac ctggcatacc gtttttttac gtatctaaac
    25741 aatgcctcca tgacatcaaa aagctagaaa aatagtccag atgattaaaa ttatcttttt
    25801 atgaaaacgg ttgctttttt attt
//
LOCUS       DATWEK010000025        25312 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.025, whole genome shotgun sequence.
ACCESSION   DATWEK010000025 DATWEK010000000
VERSION     DATWEK010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25312
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.025"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            96..344
                     /locus_tag="VCR92_001232"
     CDS             96..344
                     /locus_tag="VCR92_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEP4268299.1"
                     /translation="MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQ
                     ALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN"
     gene            381..992
                     /gene="amaP"
                     /locus_tag="VCR92_001233"
     CDS             381..992
                     /gene="amaP"
                     /locus_tag="VCR92_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEP4268300.1"
                     /translation="MLSRKEVCMSKLLKISYCLVGLVLLSVFGWVVGITGGYIYLPYS
                     YRWLSWGMDSFPNLLDSALSYYYFWTALVLFVITFLALLVIILYPRIYTEVQLRHKNK
                     KGTLLLKKSAIESYVATAIQTAGLMPNPTVTAKLYKRKFKIIVKGRLASRVAVADQIS
                     GVKEGIEKGLTEFFGINYPVNFKVYVKDIADSDRKHITRNRVE"
     gene            1003..1191
                     /locus_tag="VCR92_001234"
     CDS             1003..1191
                     /locus_tag="VCR92_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEP4268301.1"
                     /translation="MEFYEKFKYPIIGGLVGLIIAILLMDFGLFKTLLAIIFIILGIY
                     GGLYAKKTGIIDQFLNRK"
     gene            1204..1743
                     /locus_tag="VCR92_001235"
     CDS             1204..1743
                     /locus_tag="VCR92_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEP4268302.1"
                     /translation="MTETYIKNTSKDLTSAIRGQLTYDDKVIEKIVGLALENVDGLLG
                     VNGGFFANLKDKLVNTESVRDGVNVEVGKKQVAVDLDIVAEYQKHVPTIYDSIKSIVE
                     EEVKRMTDLDVIEVNVKVVDIKTKEQFEAEKVSLQDKVSDMARSTSEFTSHQVENVKA
                     SVDNGVEKLQDQKAEPRVK"
     gene            1784..1984
                     /locus_tag="VCR92_001236"
     CDS             1784..1984
                     /locus_tag="VCR92_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEP4268303.1"
                     /translation="MSDEKYNAKLDQAGGKLKEGFGKISGDKSLETEGKVDKVTGKVK
                     EVIADAKDTVKGLAKGLDNKDK"
     gene            1995..2483
                     /locus_tag="VCR92_001237"
     CDS             1995..2483
                     /locus_tag="VCR92_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEP4268304.1"
                     /translation="MEKTQIKSTLTYDDKVIEKIVGHALENVGGLLAVTGGFFSNIKN
                     NLVNSESVTDGVSVEVGSKEVAVDLAIIVEYGKDIPAIAESIKAIVSQNVDSMTHLKV
                     VEVNVNVVDIRTKEEHEAASVTVQDRVTNAASSTSQFVSEQTEKLKDTISDTVNSDEA
                     AK"
     gene            2646..3287
                     /locus_tag="VCR92_001238"
     CDS             2646..3287
                     /locus_tag="VCR92_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP4268305.1"
                     /translation="MISPKKEITSSKYQKIAISVAQRIANGEYEVGEKLKSRTTIAST
                     FNVSPETARKGLNILADLKILTLKHGSGAIVLSKERAIEFINQYESTHSIAVLKEKIR
                     ETINDQGKAMEKMAVLVNDFLMQSQSVSKQYPLAPYEIICSQDSEHFGKSIGVLNIWH
                     QTGATIVAIEHAGQFIVSPGPYSVIEKGDHIYFVGDESVISRMKTFFNLRKGL"
     gene            complement(3430..3972)
                     /locus_tag="VCR92_001239"
     CDS             complement(3430..3972)
                     /locus_tag="VCR92_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEP4268306.1"
                     /translation="MTKRHTETKAYVKTALTTLLTEQSFETLTVSDLTKKAGINRGTF
                     YLHYTDKFDMMNHFKNDTLDDLYRLLNQAEIYTDTRQVLNQTLSYLIEHREFITALAT
                     ISYLKFPQLIKDFCYQFLTTITGFQDIVTNQYHIPYPYALEVYLASIESIISYWIANG
                     YQETTEEVADIILKAVTLDN"
     gene            4090..4791
                     /locus_tag="VCR92_001240"
     CDS             4090..4791
                     /locus_tag="VCR92_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4268307.1"
                     /translation="MAFIELKQVSKSYQVGETTVFANHEVSFEINKGELVVILGASGA
                     GKSTVLNILGGMDTVDAGQVIIDGKDIAHYTSKALTQYRRNAIGFVFQFYNLVPNLTA
                     KENVELAVEIVADALDPVTILKEVGLSHRLDHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILTLLQDMARTKGTTVVIVTHNAAIAPIADRVIFMHDAQVTK
                     TVINKEPASIETIDY"
     gene            4806..7442
                     /locus_tag="VCR92_001241"
     CDS             4806..7442
                     /locus_tag="VCR92_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEP4268308.1"
                     /translation="MIKKTLWKDILRAIKNSKGRFISLFFLMALGSFALVGLKVTGPD
                     MERTASRYLERHQVMDLTVLASHQFSQADKQELDTLKGAHLEYGHLLDVSLTSNQKSL
                     RLYSVPKKVSKPVLVKGSWSKRETDLVLSSSLAKNYQIGDELAVTSPMEGLLTTTHFQ
                     VVGFANSSEVWSKSNLGSSSTGDGSLYAYAFVNPNVFKSAFNLLRIRFSNLRLTNAFS
                     KDYQKRVTQNQAHLDNLLKDNGQKRYDDLQNQYDLALKNGRVALAKETVKLAASEENL
                     TFLEGSALQEAKHQIEQGKQALAKEEKQLEQVQATKDKLEKPSYLTYNRSTLPGGEGY
                     HTYATSTTSISNVGNIFPVVLYLVAALVAFTTMTRYVDEERTSSGLLKAIGYSNKDIS
                     LKFLIYGLLASFLGTTLGIIGGTYLLSALISEILTGALTIGKTHLYSYWFYNGIAYLL
                     AMLSAVLPAYLIVKKELFLNAAQLLLPKPPSKGAKIWLEHLTFVWKALSFTHKVTIRN
                     IFRYKQRMLMTIVGVAGSVALLFAGLGIQSSLAKVVEHQFGDLTTYDILAVGSAKATA
                     TEQTDLASYLKQEPITGYQKVSYASLTLPVKGLPDKQSISILSSSATSLSPYFNLLDS
                     QEQKKVPIPTSGVLISEKLASYYKVKPGDQLVLTDRKGQSYKVTIKQVIDMTVGHYLI
                     MSNTYFKNHFKGLEAAPAYLIKVKDKDSKHIKETASDLLTLKAIRAVSQNANHIKSVQ
                     LVVTSLNQVMTLLVFLSILLAIVILYNLTTINIAERIRELSTIKVLGFYDQEVTLYIY
                     RETISLSLVGILLGIYLGKGLHTYIMTMISTGDIQFGVKVDAYVYLVPILVILSLLAV
                     LGIWVNRHLKKVDMLEALKSID"
     gene            7534..8130
                     /locus_tag="VCR92_001242"
     CDS             7534..8130
                     /locus_tag="VCR92_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEP4268309.1"
                     /translation="MENSIEAYLADSREKVTLGTVVDCFKGKAVSSKVVPGDVGLVNL
                     SDMGTLGIQYHQLRTFQMDRRQLLRYLLEDGDVLIASKGTLKKVCVFHKQNRDVVASS
                     NITVLRPQKLLRGYYIKFFLDSPIGQALLDAADHGKDVINLSTKELLDIPIPVIPLVK
                     QDYLINHYLRGLTDYHRKLNRAEQEWEYIQNEIQKGLG"
     gene            8141..9097
                     /locus_tag="VCR92_001243"
     CDS             8141..9097
                     /locus_tag="VCR92_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEP4268310.1"
                     /translation="MGSVERTLKMTLATIVAILIAYQLHLDYAMSAGIIALLSVLDTR
                     KSSLVVARNRLLSFFLAFGIAMMCFSLFGFTTVGFMCYLLIIIPLLYHFQIEAGLVPI
                     TVLVTHLIAKKSIALPILSNEFMLFFVGTSVALLFNAYMGPQDQQIRYYHQKVESDLK
                     GILYRFESFLLEGKGQNEGLLIKNLDKILDEALKLVYRERHNQLFQQTNYQVHYFEMR
                     RQQNRLLGQMAINVNTLMRQSKESILLSHLFHETACQLSEQNPALTLIDDIEQLLETF
                     RHGDLPQTREEFERRAVLFQLLQDLERFILLKVEFYQDYQND"
     gene            9194..10534
                     /locus_tag="VCR92_001244"
     CDS             9194..10534
                     /locus_tag="VCR92_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEP4268311.1"
                     /translation="MNEIKCPHCHTLFTINESEYSQLLEQVRGQAFDEELQKRLINEM
                     ALLEEKAKHQLHEVVAKKETAITSLTNQLEQIEKEQAYLRQEELAKKDQLIASLEAKL
                     DKLASQNALELANQLAEKDKEVVSLTNQLDKLALEKDATFQSKLATIEKERDGIKNQL
                     ALQAKESELSLASVRSDYEAQLKAANERVEFYKNFKAQQSTKAIGESLELYAETEFNK
                     VRSYAFPNASFVKDNQLSSRGSKGDYIYREVDANGVEILSIMFEMKNEADTTKTKHKN
                     SDFFKELDKDRREKDCEYAVLVSMLEADNDYYNTGIVDVSHEYQKMYVVRPQLFIQLI
                     GILRNAALNSLHYKQELALIKEQNIDITHFEEDLDQFKNAFAKNYQSASNNFKKAIDE
                     IDKSIKRMEEVRRFLTTSENQLRLANNKLEDVSVKKLTRQNPTMREKFAALKDQ"
     gene            10650..11534
                     /gene="truB"
                     /locus_tag="VCR92_001245"
     CDS             10650..11534
                     /gene="truB"
                     /locus_tag="VCR92_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEP4268312.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKVYEGQVTLGYSTTTEDASGEVVARSSLPAVLTEELVD
                     QTMTTFLGKITQTPPMYSAVKVNGRKLYEYARTGESVERPRREVTISLFERTSPLNFT
                     EDGLCRFSFKVACSKGTYVRTLAVDLGRALWVESHMSFLQRSASAGLTLETAYTLGEI
                     ADMVSKQEMSFLLPIEYGVADLPKMVIDDTELTEISFGRRLSLPSQEPLLAAFHGEKV
                     IAILEKRDQEYKPKKVLI"
     gene            11563..12495
                     /locus_tag="VCR92_001246"
     CDS             11563..12495
                     /locus_tag="VCR92_001246"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEP4268313.1"
                     /translation="MEIEYIKDYRDINQEDDTVLVLGYFDGLHRGHKALFEKAREVAN
                     KEGLKVVVFTFTESPKLAFSRFSPELLLHITYPKKRYEKFADYGVNKLYLVDFTSKFS
                     KVSSDHFITHYIKNLKAKHIVVGFDYKFGHNCTDSDYLTRNFEGQVYTIKEIKEDHRK
                     ISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGRTIGFPTANLAPIDNTYLP
                     ADGVYVTNVIVANKIYRSMTSLGKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDK
                     IRDMEKFEGIEDLTDRLEYDKRTALNWKKDSKLS"
     gene            12538..12942
                     /locus_tag="VCR92_001247"
     CDS             12538..12942
                     /locus_tag="VCR92_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEP4268314.1"
                     /translation="MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMS
                     ILSFTENGTEDIISTRSKVFQKLDVDVEELSISDLIDLIAKNPSLLRRPIIMDQKRMQ
                     IGFNEDEIRAFLSRDYRKQELRQATIKAEIEG"
     gene            12944..13222
                     /locus_tag="VCR92_001248"
     CDS             12944..13222
                     /locus_tag="VCR92_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEP4268315.1"
                     /translation="MSGNYYYPLDLSWSTEEISSVLHFLNKVELAYEKKVDAKQLLDS
                     YKTYKTIVKSKAQEKQIDRDFQKVSGYSTYQVVKKAKAIEKGFFSLGN"
     gene            13212..14000
                     /locus_tag="VCR92_001249"
     CDS             13212..14000
                     /locus_tag="VCR92_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEP4268316.1"
                     /translation="METKYAFARQIIKEAGLFIKSKMSEQLDIQVKTQFDDLVTNVDQ
                     ETQQLLMDRIHQTYPCDAILAEENDVRHPINQGNVWVIDPIDGTVNFIVQGSQFAVMI
                     AYYEQGIGQFGLIYDVMADQLLAGGGDFEVTLNGDKLPAYQEKPLERSLIGCNAGMFA
                     RNDRNLAHLIAKTLGVRVYGGAGICMVKVMKQELLAYFSFIQPWDYAAAKVLGDKLGY
                     VLLTIDGYEPDFQTRQKIMFVPKCQLTRIASFLTKDSAVTLEDQ"
     gene            14003..15313
                     /locus_tag="VCR92_001250"
     CDS             14003..15313
                     /locus_tag="VCR92_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEP4268317.1"
                     /translation="MMSLPKEFINTYQAILGKELEDFLASFNQEPVNAFRINPLKNQL
                     KTFEHPIPNTLWGYYGKLSGKSPEHVSGLVYSQEPAAQMVAQVAAPQKGSRVLDLAAA
                     PGGKSTHLLAYLDNTGLLVSNEISKKRSKVLVENIERFGARNVVVTNESADRLAKVFS
                     HYFDTIVFDGPCSGEGMFRKDPDAIQYWHHGYPAECAKLQKSILEDALTMLKPGGELI
                     YSTCTWAPEENEDVVQWLLETYTFLELVDVPKLNGMVSGIGLPETARMYPHRYQGEGQ
                     FVAKLKDKRQEGQSTKLKAPKSNLTKDQLRLWKMFEKDHLNLTLSGTLQTFGDYLYLL
                     PDGLPALDGLKIARNGLELGVFKKKRFEPSYALGLALKPDEVRSSIELREEDFRPYVS
                     GNVITLPQSYPTGWYQLLINGNGLGFAKVVDKTIKNNFPKGLRF"
     gene            15452..16318
                     /locus_tag="VCR92_001251"
     CDS             15452..16318
                     /locus_tag="VCR92_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEP4268318.1"
                     /translation="MKMKKKFFLLSLLVLSTFFLSACSSWIDKGESITAVGSTALQPL
                     VEAVADEFGSSNLGKTVNVQGGGSGTGLSQVQSGAVQIGNSDVFAEEKDGIDASKLVD
                     HQVAVAGLAVIANPKVKVSNLSSQQLQKIFSGEYTNWKQVGGEDLAISVINRAASSGS
                     RATFDSVIMKGVNAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLQLNGFK
                     ANAKNVATNDWPIWSYEHMYTKDKPTGLTKEFLDYMFSDEVQQNIVTHMGYISINDME
                     VVKSHDGKVTKR"
     gene            16329..17264
                     /gene="pstC"
                     /locus_tag="VCR92_001252"
     CDS             16329..17264
                     /gene="pstC"
                     /locus_tag="VCR92_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEP4268319.1"
                     /translation="MENQELAKKLASPSKNSRLETFGRTITFLCLALIVFIVAMILIF
                     VAQKGLSTFFVDKVNLFDFLFGKEWQPSVKNAAGIPYLGALPMITGSFLVTILSAIIA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVIVPFMRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATCWQTIWRVVLNAARP
                     GIFTAIIFGMARAFGEALAIQMVVGNSAVMPSSLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            17254..18141
                     /gene="pstA"
                     /locus_tag="VCR92_001253"
     CDS             17254..18141
                     /gene="pstA"
                     /locus_tag="VCR92_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEP4268320.1"
                     /translation="MNAKKVDKVATGTLYTIAGIIVAILASLILYILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLIVTLIISIPLSTGAGIYLAEYAKKGPVTNFIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGSLALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFYVVIPEALPGMVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NFSARFIGKKLHSKMTAAK"
     gene            18157..18960
                     /gene="pstB"
                     /locus_tag="VCR92_001254"
     CDS             18157..18960
                     /gene="pstB"
                     /locus_tag="VCR92_001254"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEP4268321.1"
                     /translation="MTEYNWNERHIITFPEETLALATKDLHVYYGAKEAIKGIDMQFE
                     KHKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVKDKKVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNYTIIIV
                     THNMQQAARASDYTAFFYLGNLIEYDKTRNIFQNAQCQSTNDYVSGHFG"
     gene            18973..19731
                     /gene="pstB"
                     /locus_tag="VCR92_001255"
     CDS             18973..19731
                     /gene="pstB"
                     /locus_tag="VCR92_001255"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEP4268322.1"
                     /translation="MTEPILQIRDLSVYYNQKKTLKDVSLDLYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKSILDHAVESSLKGASIWNEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPRIILLDEPTSALDPISAGKIEETLLLLKKDYTLAIVTRSMQQASRLSDRTG
                     FFLEGDLLECGPTKAMFMNPKRKETEDYISGKFG"
     gene            19799..20452
                     /gene="phoU"
                     /locus_tag="VCR92_001256"
     CDS             19799..20452
                     /gene="phoU"
                     /locus_tag="VCR92_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEP4268323.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLAQINKTVRAFVSHDRELAK
                     EVIEEDDTINNFETKLEKKSLEIIALQQPVSNDLRMVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPVVEEQINLMGKAVKQMVEEALNAYINADDTKAYEIAASDEIIDQY
                     FRNIQTLAVEEIRKSPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            20657..23194
                     /locus_tag="VCR92_001257"
     CDS             20657..23194
                     /locus_tag="VCR92_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEP4268324.1"
                     /translation="MKTVEHLIETFVPENYNIFLDINRQTKTFTGNVAINGEALDNHV
                     AFHQKDLDIKSILLDNEAVIYQVDNDNEVVRVELPETGMMTLVIEFSGSITDNMTGIY
                     PSYYTKNGEKKEVISTQFESHFAREAFPCIDEPQAKATFDLSLTFDQEIGEIALSNMP
                     EVNIDRREETGLWTFDTTPRMSSYLLAFALGELHGKTVESKKGTTVGVYATTAHPLSS
                     LDFSLDIAVRVINFYEDYFGVHYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDE
                     NSTVQSRQQVALVIAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVSIEAIEPSWK
                     IIEDFQTGGIPLALKRDATDGVQSVHVEVNHPDEINTLFDPAIVYAKGSRLMHMLRRF
                     IGDRDFAIGLHHYFEKYQYRNTVGRDLWNILSDTSGKDVAAFMDAWLEQPGYPVLTAR
                     LENDQLILSQKQFFIGKGEEKGRLWPIPLNTNWHGLPETLTEAEMVIPNFSQLAAENE
                     GALRFNIDNTAHYITDYQGSLLDALVTELAQLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDSKSYMVAEAVQQVVSGLKRFIDEGSLAEKSFNRLVTTIYQEDFNQHGFE
                     KKADESDEDEMVRQVALGRLWLAENQTIIDGLRTIFEAYQNNIASIPAAVRRLVLANQ
                     MKYFETDSLVDIYFETYVATTDNNLRSDLTVAFSQTKQPTTIRRILVSLKDKDIIKPQ
                     DLSYWYNALLGQSFTQDIIWEWARENWDWIKSALGGDMSFDKFVIYPASNFKTPKHLA
                     EYKSFFEPKLDDMAISRNITMGINEIEARVALITKEKEAVIAALSHY"
     gene            23541..24215
                     /locus_tag="VCR92_001258"
     CDS             23541..24215
                     /locus_tag="VCR92_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP4268325.1"
                     /translation="MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTAKEGLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRTGKFADKNISFGNLVVDLARKEVKVEGKVVELLGKEFDLLVY
                     LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKIRKKLKGTRFVNRLQTLRSVGY
                     ILKNNE"
     gene            24208..>25312
                     /locus_tag="VCR92_001259"
     CDS             24208..>25312
                     /locus_tag="VCR92_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEP4268326.1"
                     /translation="MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYS
                     SVDSSLVSVSNNASSYANRTMARISSFYFDTENNIIKALPDSDSSKLLGTPAANTDII
                     LFSANGTILNAFDAFSNYQNFHLDKRRLGSIETTSLMNFYGQEEKYHTITVRVHIKNY
                     PAVAYMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILENSEHLASSLDEVRNMRILTTNL
                     LNLARRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQNQVNRSLRMDKALLK
                     QLITILFDNAIKYTDKNGIIEIIVKTTDKNLLIS"
BASE COUNT         8044 a         4174 c         5200 g         7894 t
ORIGIN      
        1 gaaagtcgac tattaaaaga ctattgcttg aagaataaca gctgttattc ttccttggac
       61 aaaaggtaca ggagtatcta aaaaggagaa ttatcatggg acttatttgg actttaatcg
      121 tcggtgcgct tattggtgtg attgctggag cacttactaa aaaaggcggt tcaatgggct
      181 ggattgcaaa catcgctgct ggtctagttg gttcttccgt tggtcaagct ttacttggtt
      241 catggggccc ttctttagca ggaatgtctt tgatcccgtc agttattggt gccgttatcg
      301 ttgttatgat cacttctttt gtactaaaca aaactaacaa ctagtttcct ctttatttag
      361 taagtactta caaatagaga atgttaagta gaaaagaggt ctgtatgtca aaattgttaa
      421 agattagtta ttgtcttgtc ggacttgttc tattgtctgt ttttggatgg gtagttggaa
      481 taaccggagg ctatatatat ttaccttata gttatcgttg gctaagttgg ggtatggata
      541 gttttcccaa tctcttagat tcagctttat cctattatta cttctggaca gcccttgtat
      601 tatttgttat aacatttctt gccttattag ttattatttt atacccaaga atttatactg
      661 aggtccagtt acgccataaa aataaaaaag gaacactttt attaaaaaaa tcggctattg
      721 aaagttatgt tgcgaccgct attcaaactg caggtttgat gccaaaccca acagtcacag
      781 ctaaattata taagcggaag tttaagatta tcgttaaagg acgtttagct tctcgtgtag
      841 cagtggcaga tcaaattagt ggcgtgaaag aagggatcga aaaaggttta accgagttct
      901 tcggtattaa ttatcctgtt aatttcaaag tttatgttaa agatattgct gattctgatc
      961 gtaaacatat taccagaaat cgtgtagaat aggagatcta tcatggaatt ttatgaaaaa
     1021 ttcaagtacc ctattattgg tggcttggtg gggctaatta ttgccatatt gctcatggat
     1081 tttggtttat tcaaaacgct actagcaatt attttcatta ttttaggaat atatggtggc
     1141 ctgtatgcca aaaaaacagg tattattgat caatttctta atcgcaaata aaggagactt
     1201 attatgactg aaacttatat taaaaacaca tctaaagact taacttcagc aattcgtggt
     1261 caattaacat atgatgataa agtaattgaa aaaattgttg gtttagcact tgaaaatgtt
     1321 gatgggttac tgggtgtaaa tggtggtttt tttgctaacc taaaagataa attagtaaac
     1381 accgaatctg tacgtgatgg cgtgaacgtg gaagttggaa aaaaacaagt tgccgttgat
     1441 cttgatattg tcgctgaata tcaaaagcat gtgccgacta tttatgactc tattaaatcg
     1501 atcgttgaag aagaagtgaa gagaatgacc gatctggatg tgattgaagt taatgttaaa
     1561 gtagtcgaca ttaaaacaaa agaacaattt gaagctgaaa aagtaagttt acaagacaaa
     1621 gtttcagaca tggcacgttc aacatctgaa tttacgagtc atcaagttga gaatgttaaa
     1681 gcttcagtgg ataacggtgt tgaaaaactt caagatcaaa aagctgagcc acgtgtaaaa
     1741 taatcatatg tcgtcaatta ggtaagctaa aggagggttt attgtgtcag atgaaaaata
     1801 taatgcgaaa ttagatcaag ctggtggcaa gttaaaagaa ggatttggta agatttctgg
     1861 agataaatct ttagaaactg aaggtaaagt agataaagtt actggaaaag ttaaagaggt
     1921 tattgcagac gccaaagata ctgtaaaagg attagctaaa ggcttagata ataaagataa
     1981 ataaagggga catgatggaa aaaactcaaa ttaaaagcac tcttacttat gacgataagg
     2041 tcatcgaaaa aattgtcggt catgctttgg aaaacgttgg cggattacta gctgtaacag
     2101 gtggattttt ctcaaatatt aaaaataatt tggtgaattc tgagtctgta actgatggtg
     2161 tttcagttga agttggtagc aaggaagtag cagttgattt agcaatcatt gtagaatacg
     2221 gtaaagatat tcctgctatt gcagaatcta ttaaagctat tgtttctcaa aacgttgata
     2281 gtatgacaca tttgaaagtt gttgaagtca atgtgaacgt tgttgatatt cgtactaagg
     2341 aagaacatga agctgctagc gttactgttc aagatcgtgt cactaatgca gcttcaagta
     2401 cttcacaatt tgtatcagaa caaacggaaa aattaaaaga tactatctct gatactgtaa
     2461 atagtgatga ggcagctaaa taagcaatcg tctaggaagt attattgact agtggtgata
     2521 agtttgagct ggtatttacc agctcttttt gtcacggtta aaaagacacg gactattgtc
     2581 atctctctaa aaatatgatt taattagata gaaatttttc aaattgttag aaaggagtaa
     2641 attaagtgat aagtcctaaa aaagagataa caagttcaaa atatcaaaaa attgctattt
     2701 cagtagctca gcgtatcgca aatggcgaat atgaagtggg cgaaaagtta aagtcaagaa
     2761 ctactatcgc ctcgacattt aatgtatcac cagaaacggc tcgtaaaggc ctgaatattt
     2821 tagctgactt gaaaattttg actttaaaac atggtagtgg agctattgtg ctgtcaaaag
     2881 aaagagctat tgagtttata aatcaatacg aatcaaccca ttccatcgct gttttaaaag
     2941 aaaaaatacg tgagactatt aatgatcagg gaaaagcaat ggaaaaaatg gctgttttgg
     3001 tcaatgattt tttaatgcaa agtcaatctg ttagtaagca atacccatta gcaccttatg
     3061 agattatttg tagtcaagat tcggaacatt ttggcaaatc tattggtgtg ttaaatatct
     3121 ggcaccagac aggagcaact atcgtcgcta ttgaacatgc tggtcagttt atcgtttcac
     3181 caggtcctta ttctgttatt gaaaaaggcg atcatattta tttcgttggt gatgagtcag
     3241 tcatttcacg aatgaagacc ttttttaatt tacgaaaagg attataagtt tgagggccca
     3301 cctcaaactt tttttgttgc tgttgagcat tattaaaaga ggcagatcat catggtttgt
     3361 ctttccaaaa tatctgttta gacagttgtt ttggattggg agcatgattt cagactcttt
     3421 tgatgttttt taattgtcta gagtaactgc tttaagaata atatcggcaa cctcttcagt
     3481 ggtttcttga tagccattag caatccaata gctgataatg ctctcaatac tggcaaggta
     3541 aacttctaaa gcatagggat aaggaatatg gtattgattg gtcacaatgt cttggaaacc
     3601 agtaatagta gtcaaaaatt ggtaacagaa atccttgatg agttgcggaa atttgaggta
     3661 agaaatagta gcgagtgcgg ttataaattc tctatgttct ataaggtagg acaaggtttg
     3721 attgaggact tgtcgagtgt ctgtgtagat ttcagcctga tttaacaaac ggtacaaatc
     3781 atccagagtg tcatttttga aatgattcat catgtcaaat ttatcagtgt agtggaggta
     3841 gaaggttcct ctattgatac cagccttttt agtaaggtca gagacagtaa gagtttcaaa
     3901 agattgttca gttagtaagg tggttaaggc ggtctttaca taagctttgg tttcagtatg
     3961 tcttttggtc attctcaggt gctccttaaa tcaacagttg cgtcagattt gttcttgtta
     4021 aatacttatg gccattatat aataaggcta taattaaatc aacactatgt tcaaataatg
     4081 gaggggcaga tggcttttat tgaattaaaa caggtttcaa aatcttatca ggtaggagag
     4141 acgactgttt ttgccaacca cgaagtgtct tttgagatta ataaaggaga actagtggtt
     4201 attttgggag catccggagc tggtaaatcg acagtcctca atattttggg gggcatggac
     4261 acagtagatg caggtcaagt aattattgat ggcaaagaca ttgctcatta cacgtctaag
     4321 gccttaactc agtatcgtcg gaatgctatt ggtttcgttt ttcaatttta taatttggtt
     4381 cctaatttga cagctaaaga aaatgttgaa ttagcagttg aaattgtagc agatgcttta
     4441 gatcctgtga ccattttaaa ggaagtagga ctcagtcatc gtctggatca ttttcctgct
     4501 cagctctcag gtggtgaaca gcaacgggtt tcgatagcac gtgccttagc taaaaaccct
     4561 aaattgcttc tttgtgatga acctacaggt gcccttgact accaaacagg aaagcaaatt
     4621 ctaaccctct tacaggatat ggcacgaact aaggggacca cggtagttat tgtaacccac
     4681 aatgctgcta ttgctccgat agctgatcgt gtcattttta tgcatgatgc acaggttacc
     4741 aagacagtca ttaataagga acctgcaagc attgagacaa ttgattatta agaggaaggt
     4801 gtcgtatgat aaagaaaacc ttatggaagg atattttgag agctatcaag aatagtaaag
     4861 ggcgattcat ttccttattt ttcctaatgg ccttaggctc ctttgcttta gttggactta
     4921 aagtcaccgg tccagatatg gaacgaacag ccagccgtta cctcgaaaga caccaggtga
     4981 tggacctaac ggtactggct tctcatcaat tttcccaagc cgataaacaa gagttagata
     5041 cgttaaaagg ggctcattta gaatatggtc atttacttga tgtcagtcta actagcaacc
     5101 agaaatctct taggctctat agcgtgccaa agaaagtgtc taagccagtc ttggttaaag
     5161 ggagttggtc aaagcgagag acagatttgg ttttatcctc ctcacttgct aaaaactatc
     5221 agattggaga tgaactagca gtcacctcac ctatggaagg tttgctgacg acaacccatt
     5281 ttcaagtggt tggttttgcg aattcttcag aagtttggtc caagtccaat ttaggaagtt
     5341 cctcaaccgg agatggaagt ctctacgctt atgcttttgt taatccaaac gtttttaaaa
     5401 gtgcctttaa cctgctgcgc atccgtttta gtaatcttcg tctgacaaac gctttttcca
     5461 aagactatca aaaaagggta acccaaaacc aagctcattt ggataatcta cttaaagata
     5521 atggccagaa gcgttatgat gacctccaaa atcagtatga ccttgcctta aaaaatggca
     5581 gagtagcact tgcaaaggaa acagtgaaac tagctgcgag tgaggagaac ttaacttttt
     5641 tagaaggctc tgctttacaa gaagctaagc atcagattga acaaggcaaa caagcattag
     5701 ccaaggagga aaagcagtta gagcaggtgc aggctacaaa agataagcta gaaaaaccca
     5761 gttacctgac ttataatcgc tcgaccctac caggaggaga aggatatcat acttatgcaa
     5821 cttcaacgac ctccatttca aatgttggaa atatttttcc tgttgttctt tatctcgtag
     5881 ctgctctagt agcctttacc accatgacac gttatgttga tgaagaaaga acaagctctg
     5941 gtctattaaa agccattggt tattctaaca aggatatcag tttaaagttt cttatctatg
     6001 ggcttttagc cagtttttta gggacaactt taggtattat tgggggaact tacctcttat
     6061 ctgccttgat ttcagagatc ttaacaggag ctttgactat tggaaagact cacctttata
     6121 gttattggtt ttataatggc atagcttact tgctggctat gttatctgct gttttacccg
     6181 cctacttaat tgtcaaaaag gaattattcc tcaatgcagc tcagttattg ctgcccaaac
     6241 ctcctagtaa gggggcaaaa atctggttgg aacaccttac ttttgtctgg aaagccctgt
     6301 cctttactca caaggtgacc atacgtaata tttttcgcta taaacaaaga atgctgatga
     6361 ccattgtagg cgttgcaggc tcagtagccc ttttatttgc aggcttaggg attcagtcgt
     6421 cattagccaa agtagttgag catcaatttg gtgatttaac gacttatgat attttggctg
     6481 tcggttcggc caaagcgaca gcgacagagc aaactgactt agctagctat cttaaacaag
     6541 aacctattac agggtaccaa aaggtatctt atgccagctt aacccttcct gtaaagggat
     6601 tacctgataa gcaaagtatt tccattttat caagttcagc tacttctctt agcccctatt
     6661 ttaatctgct ggatagtcag gagcaaaaga aggttcccat tccaacctct ggtgttttga
     6721 tttctgagaa attagcctcc tattacaagg taaaaccagg tgatcagttg gtattgactg
     6781 atcggaaagg acagtcttat aaagtgacga ttaaacaggt tattgacatg acagttggcc
     6841 attacctgat aatgtctaat acctatttta agaatcattt taaaggattg gaggctgctc
     6901 ctgcctatct gattaaggta aaagacaaag atagcaagca cataaaggag acagccagtg
     6961 acttgttaac cttaaaagcg attagagcag tttcacaaaa cgccaatcat attaaatctg
     7021 ttcagctagt agtcacctct cttaatcagg tcatgaccct ccttgtcttc ttgtctattt
     7081 tattagcaat cgttatcctt tataacttaa cgactattaa tattgctgag cgtattcgag
     7141 aattatccac tattaaagtt ctgggatttt acgatcagga ggtcacctta tatatttatc
     7201 gagaaactat ttcgctatcc ctagtaggca ttcttttagg tatctattta ggaaaaggcc
     7261 tgcatactta tatcatgaca atgatttcaa ctggggatat tcaatttggt gtaaaggttg
     7321 atgcttatgt ttatctagtg ccaattctag taatccttag cttgttagcg gtattaggta
     7381 tctgggttaa tcgccattta aaaaaggttg atatgttaga agctttgaaa tccatagatt
     7441 gattggtgaa aagacagata tagacagcac ttgaaaagtt aatcatatta tgatagtatc
     7501 taaatactat aatttaatag aaagatacta tgtatggaaa atagcattga ggcctatcta
     7561 gcagatagca gagaaaaggt aacattaggt acagttgttg attgttttaa aggaaaagca
     7621 gtctcaagta aggttgtgcc aggtgatgtg ggattggtta atttatctga catgggcacc
     7681 ttagggattc aatatcacca attaagaact ttccagatgg atcgtaggca gctcttgcgt
     7741 taccttttgg aagacggaga tgtcttaatc gcctctaagg gaaccctaaa aaaagtctgt
     7801 gtttttcata agcaaaatcg agatgtggtg gcatcatcaa atatcactgt cttacgccct
     7861 caaaaactgt taaggggcta ctatatcaag ttctttttgg actcacctat tggtcaagcg
     7921 ctcttggacg cagcggacca tggcaaagat gtgatcaatc tctcaacgaa agaattgttg
     7981 gatattccaa ttcccgttat tcctttagtg aaacaggact atttgattaa tcactacttg
     8041 agaggattaa cagattatca tcgtaaactc aatcgagcag aacaggagtg ggaatatatt
     8101 cagaatgaaa ttcaaaaagg attaggttag gagtcttgtc atgggttcag ttgaacgtac
     8161 attaaaaatg accttggcta ccattgttgc cattttaatt gcttaccaac ttcatctgga
     8221 ttatgcaatg tcagcgggga tcattgccct gttaagtgtt ttagacaccc gtaagtccag
     8281 tttggtggtc gctaggaatc gcttgctatc ttttttcctg gcttttggga ttgcgatgat
     8341 gtgctttagc ttgtttggtt ttacgacagt aggttttatg tgttatttgt taattattat
     8401 tcctttgctc tatcactttc agatagaggc aggactggtt cctataacag tacttgtgac
     8461 acatttgatt gctaaaaaga gtattgcatt acctatttta tcgaatgagt ttatgctctt
     8521 ttttgtaggg actagtgtcg ctttactatt taatgcttat atgggtccac aagatcagca
     8581 aattcggtac tatcaccaaa aagttgaatc ggatctgaaa ggtatcttat accgttttga
     8641 aagttttcta ctggaaggaa aaggtcaaaa tgaagggctc ttgatcaaaa accttgataa
     8701 aatattagat gaagctctaa aactagttta tcgagaaagg cataatcaac tatttcagca
     8761 gaccaattat caagttcatt attttgagat gcgacgacaa caaaatagac tattgggaca
     8821 aatggctatc aacgtaaaca cgttaatgag acaaagtaag gaaagtattc ttttgtcaca
     8881 tctttttcac gaaactgctt gtcagctaag cgaacaaaat ccggctttaa ccttgattga
     8941 tgatatcgaa caattgcttg aaacctttcg tcatggtgat cttcctcaaa ctcgggagga
     9001 atttgagcga cgtgcggttt tatttcagct cttacaagac ttggaacgtt ttatcttatt
     9061 aaaggtagag ttttatcagg attatcaaaa tgactaaatc tctattgcac acttcttatc
     9121 tatgacagct tgggacttaa cttcctgagc ttttttgcta taataaaaac aagaatctca
     9181 gaatggagac aagatgaacg aaataaaatg ccctcattgt cataccctat ttactatcaa
     9241 tgagtcagag tatagtcaat tattggaaca agtcagaggg caagcctttg atgaagaatt
     9301 gcaaaaacgg ttaatcaatg agatggcctt gctggaagaa aaagcgaagc atcaattgca
     9361 tgaggttgtc gcaaaaaaag aaacagctat taccagcttg acaaaccaat tagagcaaat
     9421 tgaaaaagaa caagcctacc tcagacaaga agaactggct aaaaaagacc agcttattgc
     9481 ttctttagaa gcgaaacttg ataaattagc ctcacaaaat gctttggaac tggccaatca
     9541 attagctgag aaggacaaag aagtggttag tttgaccaat cagctggaca aattagcact
     9601 tgaaaaagat gccacgttcc agtcaaagct tgctacaatc gaaaaagaac gcgatggaat
     9661 caaaaaccaa ttggcgcttc aagctaaaga aagtgaattg tcgttggctt cggtgcgcag
     9721 cgactacgaa gcacagttaa aagcggctaa cgagcgagtt gaattttata aaaatttcaa
     9781 agcgcagcaa tctaccaagg ctatcggaga gagtctagaa ctctatgctg aaacagagtt
     9841 taacaaagta agaagctatg cttttcccaa tgctagcttt gtcaaagata accaattgtc
     9901 tagtcgtggg tcaaaagggg actatattta ccgagaggtt gatgccaatg gtgtagaaat
     9961 cctctctatc atgtttgaaa tgaagaacga ggcagacacc accaaaacaa aacataaaaa
    10021 tagtgatttt ttcaaggagt tagataaaga ccgtcgcgaa aaagattgtg agtatgctgt
    10081 tttggtaagc atgttagaag ctgataatga ttactacaat acagggattg ttgatgtcag
    10141 tcatgagtat caaaagatgt atgtggttcg tcctcaactc tttattcagt tgatagggat
    10201 tctgcgaaat gcagccctga atagtttaca ttataagcaa gagttggcct tgattaagga
    10261 acaaaatatt gacatcactc acttcgaaga ggatttggat caatttaaga atgcctttgc
    10321 taagaactat cagtctgcca gcaacaactt taaaaaggct attgacgaga ttgataaatc
    10381 gattaaacgc atggaggaag tgagacgctt tttaaccact agtgaaaatc agttacgctt
    10441 agctaataat aaattagagg atgtttcagt taaaaaactg acccgccaaa acccaaccat
    10501 gcgagagaaa tttgcagccc tcaaggacca gtaagcctga aagtgagtct ttccctgcta
    10561 aaattggtta agcgtttatt ttggcaaaac tgatgataaa gcggtagaat agaatcagta
    10621 acaattacta attagagaga aaaatagaca tgataaatgg aatcattaat ttaaaaaaag
    10681 aagccggcat gacctctcat gacgcagttt ttaaattacg gaagttatta caagaaaaaa
    10741 agattggaca tggggggacc ttagatcctg atgtggtcgg tgttctacca attgcagttg
    10801 gtaaggctac tcgtgtgatc gaatacatga cagaagctgg taaagtttat gaaggacaag
    10861 tgactctcgg ttactcaaca acgactgagg atgctagtgg agaggtagtt gcgagatctt
    10921 ctttgccagc tgtgctaaca gaagaactcg ttgatcaaac gatgacgact tttcttggga
    10981 aaatcacaca gaccccacct atgtattcag ccgtaaaggt taatggccgt aaattatacg
    11041 agtatgcgcg tactggtgaa agtgtggaac gtcctagaag agaagtgacc atttctctgt
    11101 ttgaacgcac cagccctttg aattttactg aagacggtct ttgccgattc tcttttaaag
    11161 ttgcttgtag caaggggact tatgtgcgga ccttagcagt tgatttaggt cgagctctat
    11221 gggtagagag tcatatgtcc ttcttgcagc gatcagcttc agcaggatta accctcgaga
    11281 ctgcctatac tttgggagaa attgctgata tggtttctaa acaagagatg tcttttttgt
    11341 taccgatcga gtatggcgtt gctgatcttc ctaaaatggt tattgatgat actgaattga
    11401 ctgaaatttc atttggtcgc cgtcttagtc tccctagtca agagccactg ttagctgctt
    11461 ttcatggcga aaaagtaatt gctattttag aaaaaagaga tcaagaatac aaacccaaaa
    11521 aagttcttat ttaaatagtt tgagtaagta gaatggataa ttatggaaat tgaatatatc
    11581 aaagattatc gtgatattaa ccaagaagat gatacagtct tggtattggg atattttgat
    11641 ggattacacc gtggtcataa agccttattt gaaaaagcaa gagaggttgc aaataaagaa
    11701 gggttaaaag tagtcgtttt tacgtttaca gagtctccga aattggcttt ttcgcgtttt
    11761 tctcctgagt tattgcttca tattacttat ccaaagaagc gttatgaaaa atttgccgat
    11821 tacggtgtaa ataaattata tttggttgat tttacttcta aattctctaa ggtctcatct
    11881 gatcatttta taactcatta tattaaaaac ctgaaagcaa agcatattgt tgtcggtttt
    11941 gactataagt ttgggcataa ttgtacagat agtgattatt taaccagaaa ttttgaagga
    12001 caagtttata ccattaagga aataaaagaa gatcatcgaa aaatttctgc tacatggata
    12061 aggaagctta ttcaagaagg taatgtagtt aaagcaaacc acttgttagg ctatgactta
    12121 tcgacaaggg ggagagtcgt tcacggggat gcgcgtggcc gtactattgg tttcccaaca
    12181 gccaatctag ctccaattga caacacatac ttaccagctg atggagtcta tgttacaaat
    12241 gttattgttg ctaataaaat ctatcgctct atgacgagtt taggtaaaaa tgtgacattt
    12301 ggggggaaag agttgcgtct agaagttaac atttttgact ttgacgaaga gatctatgga
    12361 gaaattattg agattgtttg gttagataag attcgagaca tggaaaaatt cgagggaatc
    12421 gaagatttga ctgatagatt ggaatatgat aaacgaacag cattaaattg gaaaaaagat
    12481 agcaaattat cttaaatttt tgtataataa ggtaagtaaa tttgatagag gaaaaatatg
    12541 gttaccttat ttttatcacc tagctgtacc agttgtcgta aagcaagggc atggttagta
    12601 aaacacgaag ttgactttca agagcataat attattacaa gtccattaag ccgtgatgaa
    12661 ttaatgtcaa tcctctcttt tacagagaat ggaacggagg atattatttc aacacgttca
    12721 aaggtttttc aaaaacttga tgttgatgta gaagagcttt caatttcaga tttaattgat
    12781 ttaattgcta aaaatccaag tcttcttcgt cgccctatta tcatggatca aaaacgcatg
    12841 caaattggtt ttaatgaaga tgaaattaga gcgtttttat cgagagatta tcgcaagcaa
    12901 gaactacgtc aagcaacgat aaaagcagaa attgaggggt gatatgtcag gtaattatta
    12961 ttatccactt gacttaagtt ggagcactga agaaatatcc tcagtgcttc attttttgaa
    13021 taaagtggag ttagcatatg aaaaaaaagt agatgcaaaa caactcctag atagttataa
    13081 gacttataaa accattgtca aaagtaaagc tcaggaaaag caaatcgacc gtgattttca
    13141 aaaagttagt ggttattcga cctatcaagt tgttaaaaaa gcgaaggcaa ttgagaaagg
    13201 attcttttcc cttggaaact aaatacgcat ttgcaaggca aatcattaaa gaagcagggc
    13261 tttttatcaa gtcaaaaatg tcagagcagc tagatattca ggtgaaaaca caatttgatg
    13321 atctggttac caatgttgat caagaaactc aacagttact gatggatcgt attcatcaga
    13381 cctatccttg tgatgccatt ttagctgaag aaaatgacgt tcgtcacccc attaatcaag
    13441 gaaatgtttg ggtcatcgat cccattgatg gaacggttaa ctttattgtg cagggatcac
    13501 agtttgcagt gatgattgcc tattatgaac aaggaattgg ccaatttggg cttatttatg
    13561 atgtgatggc agatcaatta ctagctggtg gtggtgattt tgaagttact ttaaacggtg
    13621 ataagcttcc agcttaccaa gaaaaacctt tagagcgtag cttaattggc tgcaatgcag
    13681 gcatgtttgc cagaaatgat cgtaaccttg ctcatctaat tgcaaagact ttaggtgtaa
    13741 gggtttatgg tggtgcaggt atctgcatgg ttaaggtcat gaagcaggaa ttactggcct
    13801 atttttcatt tatccaacca tgggattacg cagcagcaaa agtactaggc gataaactgg
    13861 gttatgtttt actaactatt gacggatatg agcctgattt tcaaacacgt caaaaaatca
    13921 tgtttgttcc taaatgccaa ctcactagga tagcgtcttt tctaacaaag gactctgccg
    13981 tcacacttga agatcaatag aaatgatgtc attaccaaaa gaatttatta acacttatca
    14041 agcaatacta ggcaaagaat tagaagattt cttggcaagt tttaaccaag agccggtcaa
    14101 tgcttttcgg attaacccct taaagaatca actaaaaacc tttgaacacc ccattccaaa
    14161 taccttatgg ggatattatg gtaaactatc tggcaagtct ccagagcatg tgtcggggtt
    14221 ggtttattcc caagaaccag cggctcaaat ggtggcacaa gtagcggctc ctcaaaaggg
    14281 gagtcgtgtt ttagacttgg cagctgcacc aggaggaaaa tcaactcatt tattagctta
    14341 tttagacaat acaggtcttt tagtcagcaa tgaaatttct aagaagcgca gcaaggtttt
    14401 agttgaaaat atcgaacgtt ttggcgctag aaatgttgtg gtgactaatg aatccgcaga
    14461 tcgtttagcc aaggtatttt ctcattattt tgatactatc gtctttgatg gaccatgttc
    14521 tggtgaagga atgtttcgca aggaccctga tgctattcaa tattggcatc acgggtatcc
    14581 cgcagaatgc gccaagttgc aaaaatctat tttagaagac gccttaacca tgttaaaacc
    14641 aggaggagaa ttgatatact ccacctgtac ttgggctcct gaagaaaatg aagatgttgt
    14701 gcagtggctc ttagagactt ataccttttt agaattggtc gatgttccaa aactaaatgg
    14761 aatggttagt ggtatcggac ttccagagac tgctagaatg taccctcatc gttatcaagg
    14821 ggaagggcaa tttgtggcca agctaaaaga taagcgtcaa gaaggacaaa gcactaaact
    14881 aaaagcacct aaatccaact tgaccaaaga ccagttacgt ctttggaaaa tgtttgaaaa
    14941 agaccatcta aaccttaccc tatcaggaac actacaaacc tttggtgatt acctatacct
    15001 cttgccagat ggtcttcctg ctttagatgg ccttaaaatt gctcggaacg gtttagaatt
    15061 aggcgtcttc aagaagaaac gctttgaacc ctcttacgcc ttgggattag ctttaaagcc
    15121 tgatgaggtc cgatcatcta ttgagcttag agaggaagac tttagacctt atgtgtcagg
    15181 taacgtcatt actttgcccc aatcttatcc aacaggctgg taccaattac tcattaatgg
    15241 caatggtcta ggatttgcca aggtcgttga caagaccatc aaaaataatt tccctaaagg
    15301 gttaagattt tagcgtaaaa aataatatta aaaagttaaa tatttaaaga aaaaatgctt
    15361 tcaaagcata ggtagatatg ttactataaa gaatatgtgg cacttagttt ctacatatat
    15421 accctttatt tttacgaata ggaaataaat aatgaaaatg aaaaaaaaat tctttttgtt
    15481 aagtcttttg gtcctatcaa ctttcttttt atccgcatgt tctagctgga ttgataaagg
    15541 tgagtcaata accgctgtag gatcaacagc actacaaccc ttagtagaag cagtagctga
    15601 tgaatttgga agcagtaatc taggcaagac tgtcaatgtt caaggtggtg gttcaggtac
    15661 agggttgtct caagttcaat caggagctgt ccaaattgga aatagtgatg tctttgcgga
    15721 agaaaaagat ggtattgatg cttctaaatt agttgatcat caagtagctg ttgcaggact
    15781 tgcagttatt gccaatccta aagtcaaggt ttccaatctc agtagtcagc agttgcaaaa
    15841 gattttttca ggagaatata ccaattggaa acaagttgga ggagaagatc ttgcgatttc
    15901 agtgatcaac cgagcagcaa gttctggctc acgagcaacc tttgacagtg ttatcatgaa
    15961 aggggtcaac gctaaacaaa gtcaagagca agactccaat gggatggtta aatcgattgt
    16021 ttcacaaaca ccaggtgcca tttcttacct ttcctttgcc tacgttgatt catctgttaa
    16081 atctttgcaa ttaaatgggt ttaaggcaaa tgctaagaac gtggctacaa atgattggcc
    16141 aatctggtcc tacgaacaca tgtataccaa agataaacca acagggttga ccaaggaatt
    16201 tcttgattat atgttttcag atgaagtaca acagaacatt gttacacata tgggatatat
    16261 ttcgataaat gatatggaag tggtcaaatc tcatgatgga aaagtaacaa aaaggtaatg
    16321 gaggaattat ggaaaatcag gaattggcta aaaaattagc ctcaccatca aagaattcaa
    16381 gacttgaaac ctttggccgc accattacgt ttttgtgtct ggctttgatt gtttttatcg
    16441 ttgcgatgat tctgatcttc gttgctcaaa aagggttgtc aaccttcttt gttgacaagg
    16501 ttaatctttt tgatttcttg tttggaaagg agtggcaacc aagtgtgaaa aatgcggccg
    16561 gcattcctta tcttggtgct ctgccaatga ttacaggatc ctttttggtt accattttat
    16621 ctgctattat tgccacccca tttgccattg gcgcagccgt ttttatgact gaaatctcac
    16681 ctaaatatgg cgctaaatta ttacagcctg cggttgagct tttggttgga attccttcgg
    16741 ttgtttatgg gtttatcggt ttgcaagtga ttgttccttt tatgcgctct atctttggtg
    16801 gcacaggttt tggaatccta tctggggtct gtgtcttgtt tgttatgatt ttaccaacag
    16861 tgacttttat gacaacagac agtctgcggg cggtgcctcg tcattaccgc gaagcgtcta
    16921 tggctatggg agcaacctgt tggcaaacca tttggcgtgt tgttcttaat gcagctcgtc
    16981 caggtatttt tactgccatt attttcggga tggcgagagc ttttggtgaa gccttagcca
    17041 ttcaaatggt tgtcggtaac tctgctgtaa tgccaagttc actaacgaca ccagccgcaa
    17101 ccttaacgtc tgtcttgaca atgggtattg gtaacacggt tatgggaacg gtccaaaata
    17161 atgtgctttg gtcccttgcc ctagtcttat tattaatgag tctggccttc aattcccttg
    17221 tcaaattaat cacgaaagaa agaaagagaa attatgaacg ctaaaaaagt cgataaagta
    17281 gcaactggta ctctttatac cattgctgga attattgtag ctattttagc ttccttaatt
    17341 ctatatatcc ttgtccgtgg cttgccacac atcagctggt cctttttaac aggaaaatcg
    17401 tcttcgtacg aagctggtgg gggaattggt atccagttgt ataattcctt cttcctattg
    17461 attgttaccc tgattatttc cattccttta tcaactggag cggggattta cttggctgaa
    17521 tatgccaaaa aagggcctgt taccaacttt attagaacct gtattgagat tctgtcttcc
    17581 ctaccatctg tggttgtagg gctctttggt tacttgattt tcgttgtgca gtttgaatat
    17641 ggcttttcta ttatttcagg gtctcttgct ttgacggtct ttaatcttcc tcaaatgacc
    17701 cgtaatgttg aagatagttt actgcatgtt catcataccc aaagagaagc aggattagct
    17761 ttaggcctgt cacgctggga aacagttttt tatgtggtta tcccagaagc tctcccgggg
    17821 atggtaacag gtattgtctt agcttcaggt cgtatttttg gtgaagcggc agcgcttatc
    17881 tatactgctg gtcaatcagc accagctctg gattggtcaa attggaatcc acttagtgtt
    17941 actagtccaa tctctatttt ccgtcaatct gagacccttg ctgttcatat ttggaaagtc
    18001 aatagcgaag ggacaattcc agatgctact cttgtatccg caggaagtgc agcagtgcta
    18061 ttaattttta tccttatttt caacttttca gctcgcttta ttgggaagaa acttcattct
    18121 aaaatgacag cagcgaaata agatattgga gaaatcatga cagaatataa ttggaatgaa
    18181 cgtcatatca tcacttttcc tgaagaaacg cttgctctag ctaccaagga tttacatgtt
    18241 tactatggtg cgaaagaagc tatcaaaggg attgatatgc agtttgaaaa acataaaata
    18301 acagccttga ttggtccatc tggttgtggc aaatcaactt atcttcgtag tcttaaccgc
    18361 atgaacgata ccattgatat tgctcgggtt acaggtgaga ttctttatca gggcattgat
    18421 gttaatcgaa aagacatgaa tgtttacgag attcgcaagc acttaggaat ggtttttcaa
    18481 agacccaatc ctttcgctaa atccatttat aaaaacatta cctttgccca tgaaagagct
    18541 ggtgtgaaag acaaaaaagt tttagatgaa attgttgaga cttcactgaa acaagccgcg
    18601 ctttgggatc aagttaaaga tgaccttcac aaatcagcct tcaccttatc agggggtcag
    18661 caacaacgct tgtgtattgc tagagccatt tctgtcaaac ctgatattct attaatggat
    18721 gaaccagcct ctgcccttga cccgattgca acgatgcagc tggaagaaac catgtttgaa
    18781 ttgaagaaga attacacgat tattattgtg acccacaata tgcaacaagc agctcgtgcc
    18841 agtgattaca ctgccttctt ctatttaggc aacctcattg aatatgataa gacacgtaat
    18901 attttccaaa atgcgcaatg tcagtcaaca aacgactacg tttcagggca ctttggttag
    18961 aaaggtaata tgatgacaga acctatttta cagatcagag acctttctgt ttactacaat
    19021 caaaagaaaa cgttaaaaga tgtctctttg gacctttatc caaatgaaat aacagcttta
    19081 attggtcctt ctggatctgg gaaatcaacg ctcttgcgtt ctatcaaccg tatgaatgat
    19141 ttgaatcctg aagtaaccat tacaggctct atcgtctata acggacacaa tatttatagt
    19201 ccaaggacag atacggttga tctacgcaaa gaaattggta tggtattcca acaacccaac
    19261 ccatttccga tgtctattta tgagaacgtg gtttacggcc ttcgcttaaa aggtatcaga
    19321 gataaatcaa tcttagacca tgctgttgaa agctctctta aaggggcttc catttggaat
    19381 gaagtcaaag atcgtttaca tgattctgcg gttggcttat caggcggaca gcaacagaga
    19441 gtttgcatag ctagagttct tgctaccagc cccagaataa tccttttaga tgaacctacc
    19501 tcagctcttg atcctatctc agctgggaaa attgaagaaa cattattgtt attaaaaaaa
    19561 gattatacac tggctattgt gacccgctca atgcagcaag cctcacgttt atcagatcga
    19621 acaggttttt tcttggaggg tgacttactt gagtgtggtc ctacaaaagc tatgtttatg
    19681 aatcctaagc gcaaagaaac cgaagactat atttctggta aatttggttg agaaagacgt
    19741 atatggttga cccctctgtg tttttattat aatgactaga ttgtaggaag aaaaaatcat
    19801 gttaagaacg aaatttgaag aagaattaga taaattgcat aaccagtttt attcaatggg
    19861 aacggaagta ttggcacaaa tcaataaaac tgttcgtgcc tttgttagtc atgatcgtga
    19921 attggccaaa gaagttatcg aagaagatga cactattaat aattttgaga caaagcttga
    19981 aaagaaatcg ctggaaatta ttgccctaca acagccagtt tcgaatgatc ttagaatggt
    20041 tattactgtt ttaaaggcat caagtgatat tgaacgtatg ggtgaccatg ctgcttcgat
    20101 tgccaaggcc actattcgta tgaaaggtga ggagcgtatt ccagtggttg aagaacaaat
    20161 caaccttatg ggaaaagctg tgaaacagat ggtagaagaa gcccttaatg catatatcaa
    20221 tgctgacgat acaaaagctt atgaaatcgc agcttctgat gagattatcg atcaatattt
    20281 ccgtaatatc caaaccttag ctgttgaaga aatccgtaag tctccagatg ctgtttttgc
    20341 aggaaaagaa tattttcaag tattaatgta tttggaacgt attggtgact atgctcgcaa
    20401 catttgtgaa tggattgttt atcttaaaac tggaaaaatt attgaattat aagaaattat
    20461 gctataatga gactgggaaa cagcttgcca gtccctggtt ttatacgaaa ttgtgcaagt
    20521 tagaaaatga actaacaaga aaagttttct ttgctgaatc tgattttgtt aggttaacaa
    20581 atatatgtag acagagatga tacttaggta tcatctgttg atctattatg atttgttatt
    20641 agaattaagg agttatatga agacagtaga acatctcatc gaaacatttg tgcctgaaaa
    20701 ttataacatc tttttagata ttaatcgtca gactaaaaca tttacgggga atgttgcgat
    20761 taatggtgaa gctttagata atcatgtggc tttccaccaa aaagatttgg acattaagtc
    20821 tattttgctc gataatgaag ctgttattta tcaagtggat aacgacaatg aagttgtgcg
    20881 tgttgaatta cctgaaacag gaatgatgac gcttgtcatt gaattttcag gtagcattac
    20941 agataatatg acaggtattt acccttcata ttacactaaa aatggtgaga aaaaagaagt
    21001 catttcaact cagtttgaaa gccattttgc acgtgaagct ttcccatgta ttgatgaacc
    21061 acaagcaaaa gctacttttg atttaagctt gacctttgat caagaaattg gtgagatagc
    21121 gttatcgaat atgccagaag tcaatattga ccgtcgcgag gagactggtc tttggacatt
    21181 tgatacgaca ccaagaatgt catcttactt gctagcgttt gcgctaggag aacttcatgg
    21241 aaagactgta gaaagcaaaa aaggaacaac tgttggtgtg tatgcgacaa cagcgcatcc
    21301 tcttagctcg cttgattttt cattggatat tgcagttcgt gttatcaact tttatgaaga
    21361 ctattttgga gtacattacc caatcccgca atctcttaat attgcgcttc cagatttttc
    21421 atctggtgct atggaaaatt ggggtttaat cacttatcgt gaaatttatt tattagtaga
    21481 tgaaaattcg actgttcaaa gccgacaaca agttgcactt gtaatcgccc acgagatagc
    21541 acaccaatgg tttggaaact tggttacaat gaaatggtgg gacgatctgt ggttaaatga
    21601 gagttttgcc aacatgatgg aatatgtctc tatcgaggct attgagccgt cttggaaaat
    21661 aatagaagat ttccaaacag gtggtattcc tcttgcttta aaacgtgatg ctactgatgg
    21721 tgttcaatca gtgcatgttg aagtcaatca tccagatgag ataaatacat tgtttgatcc
    21781 tgctattgtc tatgcaaaag gtagtcgttt gatgcatatg ttacgccgtt ttattggtga
    21841 tcgtgatttt gccattggct tacatcacta ctttgaaaaa tatcaatatc gaaatactgt
    21901 cgggcgtgat ttatggaata ttttatcaga tacttcaggc aaagacgtag ctgcttttat
    21961 ggatgcttgg cttgaacaac caggttatcc agttttaaca gctcgccttg aaaacgatca
    22021 attgattttg agtcaaaaac aattttttat tggaaaaggt gaagaaaaag gtcgcctttg
    22081 gccgattcct ttaaacacta attggcatgg ccttcctgaa actttgacag aggcagaaat
    22141 ggtcattcca aactttagtc aattggcagc agaaaatgaa ggagctctac gtttcaatat
    22201 tgataataca gctcattaca ttacagacta ccaaggatca ttattagatg ccttagtcac
    22261 tgaacttgcc caacttgata atacttctgc tttacaagtt attcaagaac gtcgtttatt
    22321 ggcagatagt ggcttgattt cctatgctga attggttgac ttaattgctc aattggacga
    22381 ttctaagtct tatatggtag cagaagcggt tcagcaagtg gtctctggtt tgaaacgctt
    22441 cattgatgaa ggaagcttag cagaaaaatc ctttaatcgc ttggtaacca ccatctatca
    22501 agaagacttt aatcagcatg gttttgagaa aaaagctgac gaatcagatg aagatgagat
    22561 ggtacgtcag gttgccttgg gccgcttgtg gctagcagaa aatcagacga ttattgacgg
    22621 attgagaact atttttgaag catatcaaaa caatattgca agtattccag cagctgttcg
    22681 tcgcttggtt ttagccaacc aaatgaaata ttttgaaaca gatagcttgg ttgatattta
    22741 ttttgagact tatgtagcaa ctactgataa taatttacgc agtgatttaa cggttgcttt
    22801 tagtcaaaca aaacaaccaa ctactattag acgtattctt gttagtttaa aagataaaga
    22861 tattattaaa cctcaggatt tatcttattg gtacaatgct ttgcttggac aaagctttac
    22921 tcaagatatc atttgggaat gggctagaga aaattgggat tggattaaat ctgcacttgg
    22981 tggagatatg agctttgata aatttgttat ttatccagca agtaacttta aaacaccaaa
    23041 acatctagca gaatataaat ctttctttga acctaagcta gatgatatgg ctattagccg
    23101 taatattacc atgggaatta atgaaattga agcacgtgtt gctttgatca ctaaagaaaa
    23161 agaagcagtt attgcagctc tcagtcatta ctagaccata agcaaaagag ttgggaggac
    23221 tttccagctc ttttttgtag tgagctagct tcctttctta gttccgtcta taactaaatg
    23281 attatccata gtttaattca aaaggagatt gcactttaaa gcgaaggcta ttagcctctt
    23341 aatacttttt ttaccaggtg gtgaataaga acaattataa atgatttaat cattatgctt
    23401 taaatgcctt aaaggagtat taatatttta gtaaacctta agctttttgt agtatagtct
    23461 cgttagaaat tgttatcaga aatgagacta agttaaatga agtgatagtt actttattta
    23521 agaacaattg aggtagagac atgataaaaa tattattagt agaagatgac ttgagcttat
    23581 caaattccat ttttgatttt ttagatgatt ttgcagacgt catgcaagtt tttgatggcg
    23641 atgaaggttt atacgaagca gaaagtggta tttatgattt gattttgtta gaccttatgt
    23701 tgccggagaa aaatggcttt caagtcttaa aagaattgcg agaaaaagat attaaaattc
    23761 ctgtattgat catgacagct aaagagggtt tagatgataa aggtcacgga tttgaattag
    23821 gtgctgatga ttatctgaca aagccgttct atttagaaga gttaaaaatg cgaattcaag
    23881 cactgttaaa aagaacaggg aaatttgcag ataaaaatat tagttttggc aatttagtgg
    23941 tcgacttagc tcgaaaagag gtgaaggttg aagggaaagt agttgaatta cttggcaaag
    24001 aatttgattt gttggtgtat cttttgcaaa atcaaaacgt tattttacca aagacacaaa
    24061 tttttgatcg tttatgggga ttcgatagtg atactacgat ttcggttgtt gaagtttaca
    24121 tttctaaaat aaggaaaaaa ttaaaaggta cccgttttgt taacaggctt caaactttaa
    24181 gaagcgtagg gtatattcta aaaaacaatg aataaattaa aaaaagagat tttatcagat
    24241 aactataacc acttttttca tttttttgcg gtttttacag gtatttttgt cattatgact
    24301 attattatct tacagattat gcggtttggc gtttattcgt cagttgatag tagtttagtt
    24361 tctgttagta ataatgcaag tagctatgct aatcgtacga tggctagaat atcttctttt
    24421 tactttgata ctgaaaataa cattattaag gcgctgcctg attcagatag ttctaagtta
    24481 ttaggaacgc ctgcagctaa tacagatatc attttgttta gtgctaatgg aacaatttta
    24541 aatgcttttg atgcgttttc taactatcaa aattttcatt tagataaacg ccggttgggg
    24601 agtattgaaa ccaccagttt aatgaatttt tatggacaag aagaaaaata ccatacgata
    24661 actgtaaggg ttcatatcaa aaattatcct gcagttgcct atatgatggc agtagtaaat
    24721 gtggaacaat tagaccgcgc taatgaacgt tacgagcgca ttattattat agttatgagt
    24781 gttttttggc taatttctat tttagcaagt atttatttag ccaagtggag cagaaaacct
    24841 attttagaaa gctatgaaaa acaaaaaatg tttgttgaaa atgctagtca tgaactaagg
    24901 acccctttgg cggtcttaca gaatcgtctg gaatcgcttt ttcgtaagcc caacgaaacg
    24961 atattagaaa atagtgagca tctcgcttct agtttagacg aggttcgcaa catgcgcatc
    25021 ttaacaacta atttattaaa tttagcaaga cgagatgatg gcattaatcc acagtggact
    25081 catttagata cagatttttt taatgctatt tttgagaatt atgaactagt tgctaaagaa
    25141 tatggaaaaa tattttattt tcagaaccaa gtcaatagat cgttaagaat ggataaggct
    25201 ttactaaaac aattaataac gattttattt gacaatgcta ttaaatatac agataaaaat
    25261 ggtattattg aaattatagt gaaaacaacg gacaaaaatt tattaatttc tg
//
LOCUS       DATWEK010000026        25273 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.026, whole genome shotgun sequence.
ACCESSION   DATWEK010000026 DATWEK010000000
VERSION     DATWEK010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25273
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.026"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(525..911)
                     /gene="rplQ"
                     /locus_tag="VCR92_001260"
     CDS             complement(525..911)
                     /gene="rplQ"
                     /locus_tag="VCR92_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEP4268327.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(926..1864)
                     /locus_tag="VCR92_001261"
     CDS             complement(926..1864)
                     /locus_tag="VCR92_001261"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEP4268328.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIKIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELEVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIAEGHSLRATMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTEVAKATEVMKETEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            complement(1910..2293)
                     /gene="rpsK"
                     /locus_tag="VCR92_001262"
     CDS             complement(1910..2293)
                     /gene="rpsK"
                     /locus_tag="VCR92_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEP4268329.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(2311..2676)
                     /gene="rpsM"
                     /locus_tag="VCR92_001263"
     CDS             complement(2311..2676)
                     /gene="rpsM"
                     /locus_tag="VCR92_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEP4268330.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDIR
                     VKDLTSDQEDAIRREVDAIKVEGDLRREVNMNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(2694..2810)
                     /gene="rpmJ"
                     /locus_tag="VCR92_001264"
     CDS             complement(2694..2810)
                     /gene="rpmJ"
                     /locus_tag="VCR92_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEP4268331.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            complement(2836..3054)
                     /gene="infA"
                     /locus_tag="VCR92_001265"
     CDS             complement(2836..3054)
                     /gene="infA"
                     /locus_tag="VCR92_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEP4268332.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(3172..3810)
                     /locus_tag="VCR92_001266"
     CDS             complement(3172..3810)
                     /locus_tag="VCR92_001266"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEP4268333.1"
                     /translation="MNLLIIGLPGAGKGTQAAKIVEEFGVAHISTGDMFRAAMANQTE
                     MGRLAKSYIDKGELVPDEVTNGIVKERLAEDDIAEKGFLLDGYPRTIEQAHALDATLE
                     ELGLRLDGVINIKVDPSCLVERLSGRIINRKTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNMAQGEPILEHYRKLGLVTDIEGNQEITDVFADVEKALLELK"
     gene            complement(3960..5264)
                     /gene="secY"
                     /locus_tag="VCR92_001267"
     CDS             complement(3960..5264)
                     /gene="secY"
                     /locus_tag="VCR92_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEP4268334.1"
                     /translation="MFLKILKDALKIKTVRNKIFFTIFIILVFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSNVALVKTPDIKTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPSAIATIREDYFVNVKASDLHSSYLI
                     VGILIIAVLAIVFFTTYVQQAEYKIPIQYTKLMQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFVQNGRDLPWLNRLQEIFNYQTPVGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEQFMSALLKKLATVGAIFLAFISLAPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNTAE"
     gene            complement(5281..5721)
                     /gene="rplO"
                     /locus_tag="VCR92_001268"
     CDS             complement(5281..5721)
                     /gene="rplO"
                     /locus_tag="VCR92_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEP4268335.1"
                     /translation="MKLHELKAAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNVFDDGTEVTPAILKDAGIV
                     RAEKSGVKVLGNGELTKKLTVKAAKFSKSAEAAIIAKGGSIEVI"
     gene            complement(5936..6118)
                     /gene="rpmD"
                     /locus_tag="VCR92_001269"
     CDS             complement(5936..6118)
                     /gene="rpmD"
                     /locus_tag="VCR92_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEP4268336.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            complement(6133..6627)
                     /gene="rpsE"
                     /locus_tag="VCR92_001270"
     CDS             complement(6133..6627)
                     /gene="rpsE"
                     /locus_tag="VCR92_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEP4268337.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGR
                     VGFGTGKAQEVPEAIRKAVEAAKKNMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            complement(6646..7002)
                     /gene="rplR"
                     /locus_tag="VCR92_001271"
     CDS             complement(6646..7002)
                     /gene="rplR"
                     /locus_tag="VCR92_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEP4268338.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKDVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(7107..7643)
                     /gene="rplF"
                     /locus_tag="VCR92_001272"
     CDS             complement(7107..7643)
                     /gene="rplF"
                     /locus_tag="VCR92_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEP4268339.1"
                     /translation="MSRIGNKVITMPAGVELTNNNNVITVKGPKGELTREFNKNIEIK
                     VEGTEITVVRPNDSKEMKTIHGTTRANLNNMVVGVSEGFKKDLEMKGVGYRAQLQGTK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            complement(7846..8244)
                     /gene="rpsH"
                     /locus_tag="VCR92_001273"
     CDS             complement(7846..8244)
                     /gene="rpsH"
                     /locus_tag="VCR92_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEP4268340.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEVIEDDKQGIIRVFLKYGKNGERVITNLKRISKPGLRVYAKRDDMPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(8395..8580)
                     /locus_tag="VCR92_001274"
     CDS             complement(8395..8580)
                     /locus_tag="VCR92_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEP4268341.1"
                     /translation="MAKKSMIAKNKRPAKHSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            complement(8596..9138)
                     /gene="rplE"
                     /locus_tag="VCR92_001275"
     CDS             complement(8596..9138)
                     /gene="rplE"
                     /locus_tag="VCR92_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEP4268342.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEISFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            complement(9162..9467)
                     /gene="rplX"
                     /locus_tag="VCR92_001276"
     CDS             complement(9162..9467)
                     /gene="rplX"
                     /locus_tag="VCR92_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEP4268343.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLKALPKVNKVIVEGVGMIKKH
                     QKPNTENPQGAIVEKEAPIHVSNVQVLDKNGVAGRVGYKVVDGKKVRYSKKSGEVLD"
     gene            complement(9546..9914)
                     /gene="rplN"
                     /locus_tag="VCR92_001277"
     CDS             complement(9546..9914)
                     /gene="rplN"
                     /locus_tag="VCR92_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEP4268344.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            complement(9939..10199)
                     /gene="rpsQ"
                     /locus_tag="VCR92_001278"
     CDS             complement(9939..10199)
                     /gene="rpsQ"
                     /locus_tag="VCR92_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEP4268345.1"
                     /translation="MERNQRKTLYGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEKAVII"
     gene            complement(10225..10431)
                     /locus_tag="VCR92_001279"
     CDS             complement(10225..10431)
                     /locus_tag="VCR92_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEP4268346.1"
                     /translation="MKLQEIKDFVKELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     EKTARLDEVKKQIARVKTVQSEMK"
     gene            complement(10441..10854)
                     /gene="rplP"
                     /locus_tag="VCR92_001280"
     CDS             complement(10441..10854)
                     /gene="rplP"
                     /locus_tag="VCR92_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEP4268347.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(10858..11511)
                     /gene="rpsC"
                     /locus_tag="VCR92_001281"
     CDS             complement(10858..11511)
                     /gene="rpsC"
                     /locus_tag="VCR92_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEP4268348.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELADASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRGQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(11524..11868)
                     /gene="rplV"
                     /locus_tag="VCR92_001282"
     CDS             complement(11524..11868)
                     /gene="rplV"
                     /locus_tag="VCR92_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEP4268349.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            complement(11884..12162)
                     /gene="rpsS"
                     /locus_tag="VCR92_001283"
     CDS             complement(11884..12162)
                     /gene="rpsS"
                     /locus_tag="VCR92_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEP4268350.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            complement(12302..13135)
                     /gene="rplB"
                     /locus_tag="VCR92_001284"
     CDS             complement(12302..13135)
                     /gene="rplB"
                     /locus_tag="VCR92_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEP4268351.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKSKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLANIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(13153..13449)
                     /locus_tag="VCR92_001285"
     CDS             complement(13153..13449)
                     /locus_tag="VCR92_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEP4268352.1"
                     /translation="MNLYDVIKKPVITEKSMIALEAGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(13449..14072)
                     /gene="rplD"
                     /locus_tag="VCR92_001286"
     CDS             complement(13449..14072)
                     /gene="rplD"
                     /locus_tag="VCR92_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEP4268353.1"
                     /translation="MANVKLFDQTGKEVSSVELNDAIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVEGLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVTVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            complement(14096..14722)
                     /gene="rplC"
                     /locus_tag="VCR92_001287"
     CDS             complement(14096..14722)
                     /gene="rplC"
                     /locus_tag="VCR92_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEP4268354.1"
                     /translation="MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAELSVEQFEA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRLAG
                     RMGGNRVTVQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            complement(14970..15278)
                     /gene="rpsJ"
                     /locus_tag="VCR92_001288"
     CDS             complement(14970..15278)
                     /gene="rpsJ"
                     /locus_tag="VCR92_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEP4268355.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(15477..16766)
                     /locus_tag="VCR92_001289"
     CDS             complement(15477..16766)
                     /locus_tag="VCR92_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEP4268356.1"
                     /translation="MIYNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGV
                     SIANNIISIYQSLFIALGAAVSSLIARSIGENNQNKQLNYMAGVLQVTLLLSVGLGLL
                     SVVGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQV
                     SLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPL
                     DKIIFDLSLPAAGERLMMRAGDVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMA
                     TATIILVARQLGGGKVTEIRYIIREAFILSTLMMLVMGALTYLLGPSLLPLFTQNTDA
                     QRSAMVVLLFSLLGAPATAGTLVYTAVWQGLGKAKLPFYATTIGMWVIRIGLGYVIGV
                     VWQYGLIGVWMATVLDNTSRWFILSKQFKKYQEITFH"
     gene            complement(17154..18170)
                     /gene="adhP"
                     /locus_tag="VCR92_001290"
     CDS             complement(17154..18170)
                     /gene="adhP"
                     /locus_tag="VCR92_001290"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEP4268357.1"
                     /translation="MKAVVVNQASTGVEVVEHDLPNVGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEEIGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPEGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADILVNGKEIE
                     DVPGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVAPVVEKVPVDTAPEVFDEMERGLIQGRKVL
                     DFIS"
     gene            complement(18422..21064)
                     /gene="adhE"
                     /locus_tag="VCR92_001291"
                     /gene_synonym="adhC"
     CDS             complement(18422..21064)
                     /gene="adhE"
                     /locus_tag="VCR92_001291"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEP4268358.1"
                     /translation="MTEGHNTVETTSVSVTINALVQKGLAALEEMRKLDQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPENCVQWVETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDDFVAEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPATWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKSESREDGVEKARQMVEFNGLGHSAAIHTAD
                     AELAKEFGTRIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNAVGDNVSAIN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFAEVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFDNLEKSVKIADFEAREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEAVESYAKAVYDLGCRVGIQMNFKAQGIDENEWKEHSRELAYLAYEDQCSPANPRLP
                     MVDHMQEIIEDAYYGYAERPGRRK"
     gene            complement(21373..23148)
                     /locus_tag="VCR92_001292"
     CDS             complement(21373..23148)
                     /locus_tag="VCR92_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEP4268359.1"
                     /translation="MRIKWFSFVRVTGLLLVLLYHFFKNVFPGGFIGVDIFFTFSGYL
                     ITALLIDEYTKKESIDIIGFLKRRFYRIVPPLVLMILLTIPFTFLIKKDFIANIGSQI
                     TAVLGFTTNIYEILTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGVFVWLLARRKETQ
                     KQLRGLLFLISLGIFAISFLSMFIRSFMTSNYSLIYFSSLSHSFPFFLGAMFATITGI
                     NETTVRFQKNVRLWPRQYVLAAMIGAFTLLLVLTVTLDFNHITTYLFGFALASLFASI
                     MIYAARVLHEQTPDVQEPKAITYIADISYGIYLFHWPFYIIFSQLMSHILAVILTVFF
                     SILFATVSYYIVEPLVQGRKPNLLGLEIDCSPYYKWIVGGSLALALLTLGTCMIAPKV
                     GKFEKQLLVSSLQQAQSNMERTHTLAAGDANALSDVGIIGDSVALRSSAAFSKIMPQA
                     QLDAAVSRNFKEAFDLFNNQIKSKSLSKTVVLAVGVNSLDNYSQAVQSFIEALPKGHR
                     LVLVSPYNAKNASQVAEARDYGLKLSKKYKYVTIADWYKVAVEHPDIWYGSDGVHYSE
                     DSQGAELYVSTIQTAVEKSAKKPAK"
     gene            complement(23145..23546)
                     /locus_tag="VCR92_001293"
     CDS             complement(23145..23546)
                     /locus_tag="VCR92_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268360.1"
                     /translation="MIDMQDIVKKWSITRAKLEIVSVIVILVCAISVFSVRISNKTSL
                     TYDKGRMHYTGYVINHKMNGEGKLVYPNGDIYEGTFKNGLFEGKGTFTAKTGWLYNGE
                     FHKGQANGKGVLKAKNNKVYKGIFKQGIFQK"
     gene            complement(23569..24006)
                     /locus_tag="VCR92_001294"
     CDS             complement(23569..24006)
                     /locus_tag="VCR92_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEP4268361.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSIVSSDVMMIESRATSDWEHG
                     NPIHSGTQSILKTYQINYDITKCSKQITITDFNTFDYIIGMDSDNVKNLKEMSQHQWD
                     SKIYLFREGGVPDPWYTNDFEETYQLVRKGCQDWLSRLMSKEY"
     gene            complement(24144..25142)
                     /gene="ruvB"
                     /locus_tag="VCR92_001295"
     CDS             complement(24144..25142)
                     /gene="ruvB"
                     /locus_tag="VCR92_001295"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023079556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEP4268362.1"
                     /translation="MARILDNDVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEA
                     AKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPAVEKAGDLVAILNELE
                     PGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPR
                     IANRLLKRVRDYAQIIGDGIITAQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGG
                     PVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQKAYRHLGYPYQNT"
     gene            complement(25189..>25273)
                     /locus_tag="VCR92_001296"
     CDS             complement(25189..>25273)
                     /locus_tag="VCR92_001296"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEP4268363.1"
                     /translation="YKYYFIFAALLSFKVVQELSAVDWWRL"
BASE COUNT         7459 a         5332 c         4459 g         8023 t
ORIGIN      
        1 aattttgttg gaaacggctt aaagtgacag attgtaaaag taaaaaagat attttcacct
       61 ccaaattaaa agaggatttt aaaatactta ttaataaaat attgaatagg ggataaaact
      121 aacaatatag tttgagcatc tgtttgcgat gcaagttttt ttcggacatt taaacgaggg
      181 gattacaccg tttatttgcc catgagaggt ctttaaacac ctgcataagg ttttcttatt
      241 ctgatgacct tattgtctct gagaaaactt tataaacgca tcagaagagg cttctgtgtt
      301 attgttttac tcagcttaaa agcgggagtg tcacctcata atacaacaaa acgcctgctt
      361 ataaaaagtt tctatagctt agataccttt cataaacaag cgtcacatat taacaatatg
      421 atgagtgttc ccgctaggaa aaatcctagc ggtagaccag agctagacta agaataatct
      481 ctcgattact ccatcatcat aacactcaac aaaattgata aaaattaaac taattcaata
      541 attgccattg gagcagcatc tccacggcgt ggttctgttt taagaatacg agtgtatcca
      601 ccgttacgtt ctgcataacg aggtgcaatt tctgagaaaa gtttttgaag agctgtcgtt
      661 gatgtgtatt tatcggtagc ttcatcataa ttttctgatg cgatttcgtt acgaacgtat
      721 gcagctgctt ggcgacgagc atgaagatca ccacgtttac caagagtaat cattttttca
      781 actgttttac ggatttcttt tgcacgtgct tctgtcgtta caattgattc gttgatcaaa
      841 agatctgtcg tcaaatcacg aagcattgct ttacgttgtg agctagtgcg tcctagttta
      901 cggtaagcca ttttgtcctc ctatattatt tatcgttttt tagtccgaga cctaagtcag
      961 caagtttaac cttaacttct tcaaggctct tacgtccaag attacggact ttcatcattt
     1021 caggctcaga tttttctgtt aagtcgaaga cagtgttaat gcctgcacgt tttaaacagt
     1081 tatatgagcg tacggataaa tcaagctcct cgatggtgcg gtcaagtacc ttttcatcgt
     1141 tcactttttc agtttctttc attacttcgg tagcttttgc aacctctgtt aaatcagtaa
     1201 acaggtttaa gtgttcgatc aaaactcgag cagatagacc taaagcatct tcaggaataa
     1261 ttgttccgtt tgtcatgatt tcaatcgtta atttatcaaa gccatcattg ctacctacac
     1321 gggcaggttc aacttgataa ttaacttttt taactggcgt atagattgaa tctactgcca
     1381 atgtacccac aggtgcatca tcttttttgt ttccttctgc tggcacataa ccacgttttt
     1441 tagcaacagt cattgttgca cgtagagaat gtccttcagc gattgtaaaa agataatgat
     1501 ccgggttaac aagttcgata tcactgtcag taagaatatc accagctgtt acctctgctg
     1561 gtccttctac ttcaagttcg ataatctttt cgtcttcgac gtatgatttc acagcaagtc
     1621 ccttaacatt aaggataatt tgcatgacat cttcacgtac acctgggatt gtatcaaatt
     1681 cgtgtagtac tccatcaatt ttaattgatg ttactgctgc acctggaagt gaagacaaga
     1741 gtacacgacg aagagaatta cctagagttg ttccgtagcc acgttcaagt ggttcgatga
     1801 caaatctacc gtaatcttta ttttcatcaa tttttgttat tattggtttt tcaaactcaa
     1861 tcattttttc acccctcgaa acgaaacttg tgtactattt gttatatgat tatacacgac
     1921 gacgttttgg aggacgagca ccattatgtg gcacaggggt cacatcacga attgcagtta
     1981 cttcaagacc tgcagctgct agagcacgaa tagctgattc acgacctgaa ccaggacctt
     2041 ttacagtcac ttcaacagtt tttagtccgt gttcttgtgc agattttgca gcagcttctg
     2101 cagccatttg agcagcaaat ggagtagatt tacgagaacc tttgaaacca agagcaccag
     2161 ctgatgacca tgcaagagca ttaccatgca catctgtaat cataacaata gtgttattaa
     2221 atgtagcgtg aatgtgtgca acaccagatt cgatgttctt tttcacacga cgtttacgtg
     2281 ttggtttagc caattgtttt acctcctatt ttattttttc ttacctgcaa tcgcaacagc
     2341 tttcccttta cgagtgcgag cattgttttt agtattttgt ccacggacag gaagtccacg
     2401 acgatgacgg attccacggt atgaaccgat ttccatcaaa cgtttaatgt tcatgtttac
     2461 ttcacgtcga aggtcacctt caactttgat tgcatccact tcacgacgga tagcatcttc
     2521 ttgatctgat gttaaatctt taacacggat atcttcagaa atacctgcag ctgctaagat
     2581 ttttttagat gttgcaagac caattccgta aacataagta agtgaaatta ctacgcgttt
     2641 atcatttgga atatcaactc cagcaatacg agccattttt tctcctttct attttatcct
     2701 tgacgttgtt tgtgttttgg atttgtcgga caaattacca taacacgacc attacggcga
     2761 ataactttac agtattcgca aattggttta accgatggtc ttaccttcat gttttaatcc
     2821 ctccaattat ttcgattatt taaagcggta tgtgatgcgt ccacgtgtca agtcataagg
     2881 actcatttct actgtaacac ggtcacctac taaaatacga atgtaatttt tgcggatttt
     2941 tcctgataca gttgctagaa tttgatgtcc attttccaat tcaacagtaa acattgcatt
     3001 tggcatcgtt tctactactt tgccttcaat ttcaatcacg tcttcttttg ccacgcaaaa
     3061 gtacccccta aatttcgatt tgatgtcctc tgagcacaga ggtaacaatt ataagtcaga
     3121 ctaaactagt atatcattac taatctactt atgcaagtag attagtataa tttatttgag
     3181 ttctagcaac gctttttcaa catctgcaaa aacgtctgtt atttcttgat taccttcaat
     3241 atctgtaaca agaccaagct tacgatagtg ttcaagaata ggttctcctt gagccatatt
     3301 gacgtccaaa cgacgtttaa cagtttcagg cttatcatct tcacgttgat agtaatcttc
     3361 ttctttataa tctactggtg ggttgaacac tttatggaac gtttcaccag ttttacgatt
     3421 gataatacga ccactcaaac gctctacaag acatgatgga tccactttaa tattaataac
     3481 accatctaag cggagtccta gttcttcaag tgttgcatct aaggcgtgtg cttgttcaat
     3541 agtacgtgga tacccatcaa gcaaaaaacc tttttctgcg atatcatcct cagctaagcg
     3601 ctcttttaca atcccgtttg tgacttcatc aggaaccaat tcacctttat caatataact
     3661 tttagctaaa cgtcccattt cggtttgatt agccattgcg gcgcggaaca tatcccctgt
     3721 tgagatgtga gcaacaccaa attcttcaac aatcttagct gcttgggtcc ctttaccagc
     3781 tcccggcaaa cctatgatta aaagattcat cttttcctcc tcttttaaaa taaatacata
     3841 gtaggaaatt attttccttg gtttttgttt tcaaatggca acaagaaatc gtttgatgat
     3901 aaccaagtct tattgtcatt taaaaacaaa atagaaggtt gacaatgtca acctgtattc
     3961 tattctgctg tattcataaa tccgacatat tttctcttta gaagataccc ctcaagctgt
     4021 ttcatacctt cgataccagt tgaaatcaaa atgagcaaac tagttccacc taaagcaata
     4081 ctagaagaaa ggttgagagc ttgttgtgct gctattggcg ctaaagagat aaatgctaag
     4141 aagatagctc ctacggttgc tagttttttt agcaatgcgg acataaattg ttctgtctca
     4201 cgtccagggc gaacacttgg tatatatgag gaattcttct gaagattttc tgctgtcttc
     4261 tcaggattaa cttgtacaaa ggtatagaag aatgagaaca atataatcaa caaggcgtaa
     4321 actatcattc cgactggagt ttgataatta aaaatttctt gcaaacggtt taaccacggt
     4381 aaatctctac cattttggac aaaaggaata atcgtacttg ggatagttgt aatcgagcta
     4441 gcaaagataa cgggaataac gccggctgga tttactttta atggaagata tgaacttgta
     4501 ggtgcacctt gcattagctt tgtgtattgg attggaattt tatattccgc ttgttggaca
     4561 tatgttgtaa agaaaacaat agcaagaaca gctatgatta aaatcccaac aatgagataa
     4621 gacgagtgta aatcacttgc cttaacattt acaaaatagt cttcacgaat tgttgcaatt
     4681 gcacttggaa tagacgaaat aatacccgca aagataatca ttgatacgcc attaccaaat
     4741 cctttatcgg tgatttgttc tccaagccag gtaacaataa cgctacctgt tgtcagtaat
     4801 gccccgatca gtaaatatgt tttgatgtct ggtgtcttaa caagtgcaac gttcgacaaa
     4861 gtattaaacc ctgcagtgat accaatggat tgggcaaaag ccaaaacaag tgaaatatag
     4921 cgcgtcgctt gatttaattt acgacgtcca acctcacctt gtttgcccca ctcaacaaac
     4981 ttaggtaaaa tatccatctg caataactga acaacgatag aagcagtaat atatgggcta
     5041 acccccattg aaaatactga gaaatttctc atcgcattac cactaactaa gtttaacata
     5101 tttaagaaag ggagttcact taattgctct aagctcttgg catttacacc aggtacggta
     5161 atatgtgtcc caattcggaa tacaagaatg ataaatatag taaagaaaat tttattccgt
     5221 acagtcttta tctttaacgc gtcttttagt atttttaaga acataatgag tatcccctca
     5281 ttagatgact tcgattgaac cacctttagc aataatagct gcttcagcag attttgagaa
     5341 cttagctgct tttacagtca attttttagt caattcaccg ttaccaagca ctttaacgcc
     5401 tgatttttca gctcggacaa taccagcatc ttttaaaata gccggagtca cttctgtacc
     5461 atcatcaaaa acattcagtt gatcaagatt cacaagtgca tattctttag tattaatatt
     5521 tgtaaagcca cgttttggaa tacgacggaa caatggtgtt tgtccacctt caaaacctaa
     5581 acgtacaccg ccaccgctac gagctttttg acctttttga ccgcgaccag atgttttacc
     5641 attacctgat gatgtcccac gaccaacacg gttacgtact ttacgtgagc cttcagcagc
     5701 ttttaattca tgaagtttca ttttttctcc tttttttgta aaatgctagc gcctctatga
     5761 gggaaaagga ctccctatag aaactcgcct atacattaat gatacttaag ttatccaaaa
     5821 taacttaata cagatacgca ctaaccgact actgtttgtt gccaaaaaag caaactacaa
     5881 gagtcggttt tgtgctcgtt tttaattatg aaatcagaga tttcacagtt ataacttatt
     5941 taacatcttc aacggtaacc aagtgagaaa tagctgtcac cataccacgg atagcagcat
     6001 tatcttcttt gactactgaa gagtttaatt taccaagtcc aagagcaaca acagttttac
     6061 gttgttctgg cttacgtccg ataggagact tagtcaaagt aattttaatt tgagccatga
     6121 tgatcccctt tcttatgcta agtcagaaac tgagatgcca cgaagtgcgg caacttcttc
     6181 tgcacgttta agttgtttca atccttcaac agttgcacga acaatgttga ttggagtgtt
     6241 tgaaccaaga gattttgaag taatatcagc aacacctgct aattcgatga cggcacgaac
     6301 tgcaccacca gcagcaactc cagaaccttc tacagctggt ttcaataata ctttagctcc
     6361 accgaagtta gtgtaaactt cgtgagggat tgttgtacca accattggta cttcgatcat
     6421 gtttttctta gcagcttcaa ctgctttacg gatagcttct ggaacttctt gagctttacc
     6481 agtaccaaat ccaacacgac catttccatc accaacaact acaagagctg caaagcgaag
     6541 acgacgtcca cctttaacaa cttttgtaac gcggttaatc gcaacaacgc gttcttcaag
     6601 ttcaactgca ttatctttaa atgccattat tttgtgtcct ccctattaga atttcaatcc
     6661 gttttcacga gctgcatcag ccaaggcttt aacacgtccg tgatagagat atccaccgcg
     6721 gtcaaacacc acttcagaaa tacctttagc cactgcacgt tcagcaacaa gtttgccgac
     6781 tacaacggct tgttctgttt ttgttccttt agaaacgtct ttatcaagag ttgatgcact
     6841 tgcgagcgtt acacccgcta cgtcatcaat aacttgagcg tagatgcctg tattagaacg
     6901 gaatacgttc aaacgtgggc gatcagcagt tccagagagt ttaccgcgga cgcgacggtg
     6961 gcgtttttgg cggattttgt ttttatctgg tttcgaaatc acaattttca cctcttaatt
     7021 ttaatcaatt tgtctcattg acaagttgtc gattgaactt atcgagcatg ttaaggtgca
     7081 atacttccca tacccgacta agaacattat ttacctgttt taccttcttt aaggcgtacg
     7141 tattcaccaa cgtaacggat ccctttgcct ttgtaaggct ctggtgaacg caagctacgg
     7201 atgtaagcag ctgtttgacc aacaacttct ttgttgattc cttcaactga gattgaagtt
     7261 gggttagcaa cagtgaaagt aattccttct ggagcttcaa cttcgtcttg gtgagactta
     7321 cctactgaaa ggacaagttt agtaccttga agttgagcac ggtaaccgac acccttcatt
     7381 tcaagatctt ttttgaaacc ttcagaaaca cctacaacca tgttattcaa gttagcacgg
     7441 gttgtcccat ggattgtttt catttctttt gagtcgttag gacgtacaac tgtgatttca
     7501 gtcccttcaa ctttgatttc aatatttttg ttgaactcac gagtgagttc gcctttaggg
     7561 cctttaacag taataacatt gttgttattt gttaattcaa cgcctgcagg catagtaatt
     7621 actttattac caatacgtga catgtttatt ttctcctgtt aaattgtcaa gccgcatagc
     7681 gactagtttt cacgggggtt tgatagaatg atatacttca atttatattt caaaattgaa
     7741 cacgagctgt ggtctgtgtg aaaaagataa atcttccttg agtgtaaaca cgctacgtca
     7801 gatttcctat tttcactttg tccacgacgc tcttagtatc ttaaattacc aaacgtaagc
     7861 gatcacttct ccaccaacat tcttttggcg agcttctttg tcagtcaaaa gaccttctga
     7921 tgttgaaatg attgcaattc caagtccgtt aagaacttta ggcatgtcat cacgttttgc
     7981 gtaaacgcga agacctggtt ttgaaatacg ttttaagtta gtgataacac gctcaccatt
     8041 ttttccgtat tttaagaaca cacgaatgat gccttgttta tcatcttcga taacttcaac
     8101 attttttaca aaaccttcac gtttaagaat ctcagcaatc ccttttttaa tgtttgaagc
     8161 aggtacttct aacacttcgt gttttacttg attagcatta cggatacgtg ttaaaaagtc
     8221 tgcaattggg tcagtcataa ccatttttta tattctcctc ttactagcag tttgatgcta
     8281 tcacttacta gttaatgttg tccttaaagg actttggtat cagcttatgc tcacaccgtt
     8341 ttaattaagc acaagactta atctgaagaa caaattaagt tttgtgtcat atttttacca
     8401 agaagctttg acaacacctg gaatttgacc tttgtaagcc aattcacgga agcaaacacg
     8461 acaaagttta aacttgcggt aaactgaatg tggacgtcca catttttcac agcgagtata
     8521 agcttgtgta gagtgttttg caggacgttt gttcttagca atcatagatt ttttagccaa
     8581 tttatttacc ccctattatt ttgcaaaagg cattccaagg cccttaagca attcacgtga
     8641 ttcttcgtca gtatttgcag tagtgacgat tacaatatca agaccacgta ctttatcaac
     8701 atcatcaaag ctgatttctg ggaagataag ttgttctttc acaccgagag tgtagtttcc
     8761 acgtccatca aacgattttg tcggaacgcc atggaagtca cgtacacgag gaagtgaaac
     8821 gctaaccaat ttgtctagga attcgtacat acgttcgcca cggagggtaa cttttgcacc
     8881 gatcgctaca ccttcacgaa gacggaagcc agcgattgat ttcttagctt tagtaataag
     8941 tggtttttga cctgagataa gtgctaattc agctgcagct ttctctaggt tttttgcgtt
     9001 ggatacagca tcaccaacac ccatattgag aacaattttc tcaacttttg gcacagccat
     9061 aactgatgtg taattgaatt tctctgtcaa cgcaggaatt acttcgttag tatatttttc
     9121 ttttaaacga tttgccatta tgcttctcct ttccttcgtg attaatcaag cacttcgcct
     9181 gattttttgc tgtaacgtac ttttttaccg tcaacaactt tataaccaac acgtccagct
     9241 acaccatttt tatctaatac ttgaacatta gagacatgga taggtgcttc tttttcgacg
     9301 atagctcctt gaggattttc agtgttaggt ttttggtgtt ttttaatcat tccaacacct
     9361 tcaacaataa ctttgttaac ttttgggagt gctttaagaa ctacagcttc agtgcctttg
     9421 tccttgccag caattacgcg aactttgtcg ccttttttta caaacattct ggtttctcct
     9481 attatttctt acgccccgat gggcacccta ggaaaaccta ggggactacg tttgttaatc
     9541 tgagattaaa gtacttctgg tgcaagtgat acgatcttca tgtagccacc ctcacgcaat
     9601 tcgcgtgcaa ctgggccaaa gatacgagtt ccgcgaggag ttttatcatc acggatgatt
     9661 acagcagcat tgtcgtcaaa tttgatgtat gaaccgtctg gacggcgtgc accagttttt
     9721 gtacgaacga taacagcttt aaccacatca ccttttttaa ctgctccacc aggagtagct
     9781 tgttttacag aagcaacgat tacgtcaccg atgttagcga atttacgtcc tgaaccacca
     9841 agtactttga tagtcaagat ctcacgagca ccgctattat cagcaacttt caagcgagtt
     9901 tcttgttgaa tcatttcaat tttctccttt tagtttgatt agataataac agctttttcc
     9961 actacttcca caagacggaa acgttttgta gctgaaagtg ggcgagtttc catgatacga
    10021 acgatatcgc cttctttagc aacgttgttt tcatcatgtg ctttatattt tttagaatag
    10081 ttgatacgtt taccatagac tgggtggtta cgtttagttt caactacaac tgtgattgtt
    10141 ttgtccatct tgtcagacac tacgcgtccg taaagagttt tacgttgatt acgttccatt
    10201 tagaatttct cctttcccaa tctattattt catttctgat tgcacagttt taacacgtgc
    10261 aatttgtttc ttaacttcgt caaggcgagc agtcttttca agttgacctg ctgcagcttg
    10321 gaaacgaaga tcaaacaatt cttttttgag ttcgttttct ttcttagcaa gttcttcttg
    10381 agacaatcca cgaagctctt taacaaaatc tttaatttct tgaagtttca tgtcttctcc
    10441 ttattctgct tcacgtttta cgaatttgca cttaactggt aatttgtggc tagcaagacg
    10501 taatgcttcg cgagcaattt cttcagaaac accagcaatt tcaaacatca ctttaccacg
    10561 tttaactggt gctacccaac cttcaggtgc ccctttacca gaacccatac gtacaccgat
    10621 agcttttgca gtgtatgatt tgtgtgggaa gattttaatc caaactttac caccacgttt
    10681 catgtaacga gtcatcgcaa tacgggcagc ttcgatttga cggtttgtaa tccagtggct
    10741 agttgtggct tgaagtccgt attcaccgaa tgaaacttct ttaccacctt tagcctcacc
    10801 gcgcattttt ccacggaatt cgcgacggtg tttaacacgt ttaggtacta acatttgtta
    10861 tttgcctcct ttagtgtttt tacgagctgg aagaacttct ccacggtaaa tccaaacttt
    10921 aacgccaagt ttaccataag ttgtgtcagc ttcttcccaa gcatagtcga tatcagcgcg
    10981 aagcgtgtga agtggaacag ttccttctga ataaccttca gcacgagcga tatcagcacc
    11041 gttcaaacga ccagaaactt gagttttaat ccctttagct cctgcacgca ttgtacgttg
    11101 gattgcttgt ttttgagcac gacggaaagc aacacgttgc tcaagttgac gagcaatgtt
    11161 ttcaccaaca aggtgagcat ctaaatcagg ttgtttgatt tcgatgatgt tgatgtgtac
    11221 ttgttttcca gttaatttgt taagttgacc acgaagagcg tcaacgtttg cgccaccttt
    11281 accgataacc atacctggtt tagcagtgtg aagtgaaaca ataactttgt ttactgcacg
    11341 ttcaatttca atagttgaaa ctgatgcgtc agctaattct ttattaatga atttacggat
    11401 tgcaagatct tcatgaaggt aatccgcgta ttctttttca gcataccatt tcgcatccca
    11461 gtcacggatg attccgacac gcataccaat tggatgtact ttttgaccca cgattttacc
    11521 tccttatttt tctgatacaa ctacagttac gtgagttgta cgtttgttga ttggtgaagc
    11581 tgaacctttc gcacgtggac ggaaacgttt cattgttggt ccttcgttag cgaatgtttc
    11641 agatactacc aagtttgctt tttccaaacc aaagttgttt tctgcgttag caattgctga
    11701 gttaagagtt ttctcaataa cacgagctgc tttgtttgga gtgaatttta agattgcgat
    11761 tgcgtcagca actttcttac cacggataag atcaagtact aaacgtgttt tacgaggtga
    11821 aacacgcact gtacgagcca ttgctttagc tgaagtaatt tctgccattg tgtcctcccc
    11881 ctattaacga cgtgttttct tgtcgtcagc tgcgtgacct ttgtaagtac gcgttggtgc
    11941 aaattcacca agtttgtgac ctaccatgtc ttcttggatg taaacaggta catgtttacg
    12001 tccgtcataa actgcgattg tatatccgat gaaacttggg aaaatcgttg aacgacgtga
    12061 ccaagttttg attacttttt tcttttcgtc gtttgcttga gcttcaactt ttttcatcaa
    12121 atgctcatcg acgaaaggtc cttttttaag actacgtccc attttgtagt tttctccttt
    12181 aaataatgta ccacagcggc ttgagttcaa gagcaagact ccaaaactct accgagttgg
    12241 cggaataaat agcaaagcta ttgtaacgct atttcagcaa gttttaagca acttactaag
    12301 attatttttc gttacgacga cgaacgataa gtttgtctga tttagctttc ttgttacgag
    12361 ttttaagacc aagcgctggt ttaccccatg gagttgatgg cgctttacgt ccaactggtg
    12421 ctttaccttc accaccaccg tgtgggtgat cgttagggtt cattacagaa ccacgaactg
    12481 ttgggcggat acctttccaa cggctacgtc ctgccttacc aatgttaaca agtgattgtt
    12541 gttcgttacc aacagtaccg atagttgcac ggcatgtacc aagaatcata cgaacttcgc
    12601 ctgattgaag acgaacaaga acgtatttac cttcttgacc aagtacttga gcagaagctc
    12661 cagctgcacg aacaagttct ccacctttac caggtttcaa ctcaatattg tgaacaactg
    12721 taccgacagg aatgtttgct aatggaagtg cgttaccaac tttgatatct gcatctggac
    12781 cagaaacaat acgttgacct acttcaagac ctttaggtgc aatgatgtaa gctttcacac
    12841 cgtcagtgta atgtacaagt gcgatgtttg cagtacggtt tggatcatat tcgattgttt
    12901 taacaactgc ttcaacgcca tctttgttac gtttgaagtc gatcaaacgg taatgacgtt
    12961 tgtgtccacc accttggtga cgaactgtga tgcgaccatt gttgttacga ccagctttgc
    13021 tcttaagaga aacaagcaat gatttctcag gcgtgcttgt tgtgatttcc gcgaaatcca
    13081 aagaagtcat gttacgacgg ccatttgtcg ttggtttata aactttaata cccacgttat
    13141 ttcctcctta gattattcag cttcagctgc gaacaactcg attgctttag aatcagctgt
    13201 aagagtgatg atagcttttt tagtttttga agtgaaacct gtgtaacgac caacgcgttt
    13261 tgcttttggt ttaacgttaa cagtgtttac acttgcaact ttaactccgt caaaagcagc
    13321 ttcaacagct tgtttgatca aaagtttgtg tgcacgagta tcaacttcga aagtgtattt
    13381 gcctgcttca agagcaatca ttgacttctc agtgataact ggttttttga ttacgtcgta
    13441 caaattcatt atgcaagaac ctcctcaatt gtagagattg cttctttagt aacaagaagt
    13501 ttgtctgcgt tcacgatatc aagaacactt gcagttgctg cagttgcaac agttacgttt
    13561 ggaaggttac gtgcagaaag tgctgcaaat tcatttcctt cttcaacaag aacaagtact
    13621 tttgtatcaa tgctaagagc tgaaagcact tttgcaaatt cagcagtttt tggtgctgca
    13681 aatgaaaggc cttctacagc tacaaattta tcttcagcaa cttttgctga gtaaactgat
    13741 ttcaacgcaa ggcgacgaac tttttgtgga agtttgtatc cgtatgaacg gggagttggt
    13801 ccaaagacaa caccaccacc acgccattgt ggtgagcgga tagaaccttg acgagcgcgt
    13861 ccagttcctt tttgacgcca tggtttacgt ccaccacctg atactgctga acggttttta
    13921 accgcatgag taccttggcg aaggctagcg cgttggctaa ttacaacatc aaaaacaact
    13981 gattcgtttg gttcgatacc gaagatagcg tcgtttaatt caactgagct aacttcttta
    14041 ccagtttggt caaatagttt tacgtttgcc attttaactg ttttctcctt tcttattatt
    14101 tagcagcttt aactgctgac ttgatagtga taagagattt cttagcacct ggtacgttac
    14161 ctttaataag gataacgttc ttttctggga taacttgtac aatttcaagg ttttgaactg
    14221 ttacacggtt accacccata cgtcctgcca agcgtttgtt tttgaaaacg cggttaggcg
    14281 caacaggtcc catagaacct gggcgacgat ggtaacgaga accgtgagcc ataggaccac
    14341 gtgattgacc atggcgtttg ataacacctt ggaaaccttt accttttgat gtccctgtga
    14401 cgtcaacaac atcaccagct tcaaattgtt ctacagataa ttctgcacca acttctaagc
    14461 cttcaatgtt tttgaattca cgaatgaagc gcttaggagc tgtgtttgct tttgcaacat
    14521 ggcctttggc aggtttgtta ctcaagactt cacgtttgtc atcaaaacca acctgaactg
    14581 cttcataacc gtctgtttca acagttttaa cttgaagcac aacgtttgga gttgcttcaa
    14641 tgacagtaac agggatgaat tcgcctgatt cagtgaagat ttgagtcatt cccacttttt
    14701 tccctaagat tccttttgtc atgagaaaat atttcctttt cttaataata tttcaaaaag
    14761 ttttttatga gcgttttttg tgctcaaaaa agttttttac gagcgttttt tgtgctcata
    14821 gcaagataca aagagcgtca aactcaaaat aaaaatagaa aatctaacac aaaaacttct
    14881 gtttcaagga agatttatct ttttcatgta gagtttagct cgtgttcaag ttccatcaaa
    14941 cactaactgt acttgcaaaa tctcaccgat taaagtttga tttctacgtt gacaccactt
    15001 ggaagatcaa gtttcatcaa agcatcaaca gttttttgtg ttggattgat gatgtctacc
    15061 aaacgtttgt gtgtacgcat ttcaaattgt tcgcgagaat ctttgtattt gtgagtcgca
    15121 cgaataattg tgtaaagact gcgttcagtt ggaagtggaa ctggtccagc aactgtagca
    15181 cctgtacgtg ttgcagtttc aacgattttt tctgccgctg tatcaagtgt acggtgttcg
    15241 tacgctttca aacggatacg gatttttttg tttgccatct tttctcctct cgtctattta
    15301 cgataatagg ctagctcctc aagaaaaccg acacctgttg cgtggcaatg caaccgagcg
    15361 tgtcgcaacc tcttgtatca ttgctaaagc tgtattttta cagcaccaca atataataac
    15421 agaatcattt agtcattgca agctttttag ggcatttttt caaaaaaact accttcctaa
    15481 tgaaaggtaa tttcttggta ctttttaaat tgtttagaga gaataaacca ccgactggta
    15541 ttatctaaca ctgtcgccat ccagacccct atgagtccat attgccaaac cacaccaatc
    15601 acataaccaa ggccaatgcg aatcacccac attcctatgg ttgttgcata gaagggaagc
    15661 tttgcttttc ccaaaccctg ccagacggct gtataaacta aagtgcctgc cgttgcggga
    15721 gctcctagta aagaaaaaag taaaacaacc atggcggacc tttgagcatc agtattctga
    15781 gtaaatagcg gcaagagact aggacctagc agataggtca aggctcccat aaccagcatc
    15841 atgagggtgg ataaaataaa agcttctcta ataatatacc ttatctcagt caccttaccg
    15901 ccccccagtt gcctggccac tagaataatt gttgccgttg ccatggctaa gccaggcatg
    15961 taattaaact gagtcaaggt ttctccaata gcattacctg ccaaggccgt tgtcccaaaa
    16021 cgaacaacaa tgccaataat taggacatct cctgctctca tcatcaaacg ttcaccagca
    16081 gcaggtagtg ataaatcaaa aataattttg tccaaaggtc tcatcaatcg tttcgcaacc
    16141 tgtttaatag gaataaactg acaaagtaaa aacacaccca ctaaacgaga taaaaccgtc
    16201 gcccaagcaa caccaagaag accaaatccc catacataga tagacaaggc agaaaaaatg
    16261 gcattgagta cgtttattaa taagctcact tgcataggaa tcttaggata cccttgagct
    16321 cgaacaatag ctcctaagct agttaaaagt cctagactaa caatcatacc gccgacaatg
    16381 gatagatatt gccctccaac caatgttaca gaagcttcag ctcctagcca ttctaacacc
    16441 tgatgatgtc caacaactga taacaaccct aagccgaccg aaaggaggag tgttacttgc
    16501 aagacacctg ccatatagtt taattgtttg ttctgattat tttctccaat acttcgagca
    16561 atcagactag atacagcggc tcccagcgcg ataaagaggg actgataaat actgataatg
    16621 ttgttagcta tggagacacc agagactgct acaagtccaa tttgagccac caggtaatta
    16681 tcaaccattc ccattaacat ctgtaaaata ttttctatca tagaaggcag agctaaagag
    16741 aaaatttttc ttctattata tatcatttat gtcccctaat aaaaaattct tgatcaaacg
    16801 atttttttaa acacagtcac tggactcatt cagttatttt gttccattaa tgaattcata
    16861 aagtctacct taatagcaga gtcccaagat acacgacact tagtgttaca gtaacaattg
    16921 accacatgcc aatccttaac atttacctaa cgtttataac taagaagacg aagaacaaaa
    16981 ggactccaaa cgaatttttt ctattatata atatattctt catttagcaa ctttcaatgt
    17041 atcaaaatag cactctcgag tcaaaaatgt tttctgatac tcgagagtgc tattttattt
    17101 ggaatcaagt ttaagcaact taggcttatc tcatatttaa tacatttgta tgtttagctg
    17161 atgaaatcta agaccttgcg cccttggatt aaaccacgtt ccatttcatc aaagacttct
    17221 ggagcagtgt caactggaac tttttcgaca accggagcaa ccagaccttc tgcaccaaag
    17281 gcaaaggctt cttccaagtc tttacgtgtc cctacaagtg atccgaccac tttgatacca
    17341 tctaaaacag tttttacgat agacagttcc atgtattctg atggaagacc tacggctaca
    17401 actgttccac cggcacggac actatcaatt gcttggttaa aagcaacttt agaaacagcc
    17461 gttaccacaa caccatgtgc tccaccggtt ttttcttgaa tatagcctgg aacatcttca
    17521 atttctttgc cgttaactaa aatatctgcg ccaacttctt tagctaactc aagtttatca
    17581 ttattaatgt ccactgcgac aacatgtgca ttaaagactt ttttagcgta ttgaacagcc
    17641 agatttccaa ggccacctgc cccaaagata acaatccatt ggcctggagc agcacctgcc
    17701 tctttaatag ctttataagt tgttacacca gcacaagtaa tggaagaagc ttgagccggg
    17761 tctaaacctt ctggaacttt aactgcataa tcagctgtta ctactgcata ttcactcatt
    17821 cctccatcaa cactgtatcc agcattttta acactgcgac aaagtgtctc acgtcctgta
    17881 gtacagtatt cgcaatgacc acatccttca aagaaccatg caatagagac acgatcacca
    17941 acctttaagg atgttacgcc ttctccaatt tcttctacta taccaatacc ttcgtgcccc
    18001 aaaatacgtc ctggtacctg accaaaatcg ccatgtgcaa cgtgtaaatc agtatgacaa
    18061 acgccacagt attctacttt aacaagcgct tcaccatgac caacatttgg aagatcatgc
    18121 tcaacaactt cgacacctgt actagcttga ttaacaacta cggctttcat atcagtcctc
    18181 catctaataa cgacttattt gtaatcggtt acaaataaat tgtacatctt ttcacaatta
    18241 aagtcaacag aaacctgaaa agtttctgaa acttaactgg ttaatcttat agctgtttgc
    18301 ctatctgcaa aatacttaac tacattttct gacactggat ataaatgata tatttagaaa
    18361 ataaaatgat ttcttatgac tttaatcata agaaatcatt tcctggtatc aacattaaaa
    18421 atcacttacg tcgtcctgga cgttcagcat aaccatagta agcatcttca ataatttctt
    18481 gcatgtgatc aaccattgga agacgtgggt tagcaggtga acattggtct tcataagcaa
    18541 ggtaagccaa ttcacgagaa tgttctttcc attcattttc gtcgatacct tgagctttga
    18601 agttcatttg aataccaact cggcaaccca gatcataaac agctttcgca taagattcca
    18661 ctgcttcttc tggtgtagaa gctggaagcc ctaacaattt cgcaatgtct tggtattttt
    18721 catccgcacg gtagtaatta tacttaggcc atgtcgccgt tttagctgga cgagttccat
    18781 tatagcggat aacatacggc aaaagaattg catttgtacg tccgtgtacg gtatggaatt
    18841 gtgcgccaat tttatgcgcc attgagtgag aaatacctaa gaatgcattg gcgaaagcca
    18901 tacctgccat agttgacgca ttgtgcatct tttcacgtgc ttcaaaatcg gctattttaa
    18961 ctgatttttc aagattatca aaaacaattt taatggcttg aagagctaaa ccatccgtaa
    19021 agtcattggc catttgtgac acgtaagctt cggttgcgtg tgtcaaaacg tccataccag
    19081 tatcagcagc aataaagcct ggaacagtca ataccaaagc tgggtcaaca atggctacag
    19141 ttggtgttaa tgagtaatca gcgattggat atttacgatt atttgctttg tcagagataa
    19201 cggcaaatgg tgtcacctct gaacctgttc cagaagttgt tgggatagca acaaattttg
    19261 ttttcttacc aagttctggg aatttgaacg cacgtttgcg gatatccatg aatttttgaa
    19321 cgaggtcatg gaaatcaact tctggttgct cgtagaagag ccacataact ttggctgcat
    19381 ccataggaga tcccccgcca agggcaataa tggtgtctgg tttgaaggta cgcattaatt
    19441 cagtaccttt cataacagtt gtaatgtctg gatctggttc tacttcagca aagatctgat
    19501 aaacaacttt attgcgacga agatcaagtt gttcaatgat acgatccaag aaaccaagct
    19561 caaccatagc gtgatctgta acaatcatga cacgttcaac gtcacgacat ttttgcaaat
    19621 attgaattga atcacgttcg aagtatgttt ttgaaggaac tttaaaccat tgcatattat
    19681 ttctacgtct tcctactttt ttgatgttca agagatttat agcactaaca ttatcaccaa
    19741 ctgcgttacg tccatacgaa ccacaaccaa gagtcaatga tggcaagaaa gcattgtaaa
    19801 catccccgat accaccaaat gtagaaggtg aattccagat gacgcggata gcacggattc
    19861 tagttccaaa ttcttttgcc aactctgcat ctgctgtatg aatggcagct gagtgaccga
    19921 gtccattaaa ttcaaccatt tgacgagctt tttcaacacc gtcttcacgt gattcagatt
    19981 tcaaaacagc aatgactgga gataattttt cacgtgttaa aggctcattt tctgaaactt
    20041 ctttacattc tgcagcaaga atattggttc cttctggaac agtaaatcca gcttgttctg
    20101 caatccaagt agctggtttt cctacaatat ttggatttaa ttttgcacca gcacagtttt
    20161 tgctatttgc tttggcacca aaacagaatt cttcaagaag ggctttttct tttttattta
    20221 caaaataagt atggtaagat ttgaattctg ctacaaaatc gtcgtagatt tctttatcga
    20281 tgataacagc ttgttcagag gcacagacca taccattatc aaatgattta gacatcacaa
    20341 tatcatgagc ggcttgacgg atattagctg atttttcaac ataagctgga acgttaccag
    20401 cacctacccc aagggcaggt ttcccacatg agtatgccgc tttaaccatc gcatttccac
    20461 ctgtcgcaag gatagtggca atgccgtcat gattcatcaa agcatttgtt gcttcaagtg
    20521 atggtgtttc aacccactgc acacaatttt caggagcacc agcggcaata gcagcatcac
    20581 gaacaatacg agcggcatgt gctgatgatt cttgtgctga tgggtgaaag gcaaaaataa
    20641 ttggattacg tgtttttaac gagatcaaag atttaaagat agctgttgaa gttgggttag
    20701 ttgtgggtgt aatcccacag ataacaccca ccggctcagc aattaatgtc aaacctgtca
    20761 catcatcttc ttcaataatt cctactgttt tttgatggcg catgttatta accacatgct
    20821 cacaagcaaa tagatttttt gttgctttat cttcaaagac accgcgacct gtttcttcat
    20881 aagcatgttt agcaagttca ccgtgagcat ccaaggcagc aacagaagct ttggctacga
    20941 tataatcaac ttgttcttgg tcaagcttac gcatctcttc aagagcagct aaaccttttt
    21001 gaacaagagc attaattgtc acagaaacag aggttgtttc aacagtatta tgtccttcag
    21061 tcatttgaga ctcctttatc ttgttaaaag tttcacaatt ttgtttacaa aattattata
    21121 gcactttttg aaattttgta aatcatttca caataaattt gtgaagtttt tttcaaatta
    21181 tttctgaaat cctatggtat caatattatt cattaactct ttttcagaaa tatatctaaa
    21241 aaaagccgtt ttatttctga aatcgctttc ttttaaaaac ctcaaagtac tactatttta
    21301 ccatcatcat ttgttcacaa gaaaaagcca gagcacaatg gatctgactt atctcttaga
    21361 catttcttaa ctttatttag ctggtttttt agctgacttc tcaacagcag tctggattgt
    21421 ggagacatat agttctgctc cttgactatc ttcactataa tgaacaccgt cactgccata
    21481 ccaaatatct ggatgttcaa cagcaacttt ataccagtct gcaatagtga catacttgta
    21541 ttttttggac aatttaagac catagtctct agcttctgca acctgactgg catttttggc
    21601 attatatgga gaaaccaaaa ctaaacgatg tccttttggc aatgcctcaa taaaagactg
    21661 aactgcttga gaatagttgt caagcgagtt aacacctact gctaagacaa cagtcttaga
    21721 tagactctta gacttaattt ggttattaaa taaatcgaaa gcttctttaa aattccgact
    21781 gaccgctgca tccagttgcg cttgtggcat aatttttgag aatgctgcac tagagcgtaa
    21841 tgctacagaa tcaccaataa tacctacgtc actcaaagca ttagcgtctc ctgcagctag
    21901 tgtatgtgtc cgctccatat tactttgagc ctgttgtagg gaactgacca acaattgttt
    21961 ctcaaactta ccaactttag gcgctatcat acaagttcct aaagttaata atgctaaggc
    22021 gagagaccct cctacaatcc acttatagta aggagaacag tcaatttcta aaccaagcag
    22081 gtttggtttt ctcccttgga ccaaaggttc cacaatatag taagacacag tggcaaacaa
    22141 gattgaaaag aaaactgtta gaataactgc caaaatatga gacattaatt ggctaaaaat
    22201 aatgtaaaat ggccaatgga agaggtaaat cccatagcta atatcagcta tataagtgat
    22261 agctttaggc tcttgtacat ctggtgtttg ctcatgaaga acacgcgctg cataaatcat
    22321 aattgatgcg aataagctag ccaaagcaaa gccaaataga taggtcgtga tatggttaaa
    22381 atccaatgtg accgttagca caagcaaaag tgtaaatgct ccaatcatag cagcaaggac
    22441 atactggcgc ggccataaac gtacattttt ttgaaatcga acagtagtct cgttaatacc
    22501 tgttattgtg gcaaacatcg cccctaaaaa gaagggaaaa ctgtgagaaa gactcgaaaa
    22561 ataaatcagg gaataatttg aggtcataaa agatcttata aacatgctca agaaactaat
    22621 agcaaatatt cccaaagaaa tcaaaaacag tagtcctctc agttgtttct gagtctcctt
    22681 gcgtctagct aataaccaaa caaatacacc ccacaacaag taaaaatgaa cttcaatagc
    22741 taagctccac gtatgaacaa agagatgtgg aataaattgg ctttcataac tacttcccgt
    22801 caatatttca taaatattag tggtaaatcc taaaacagct gtaatctgac ttcctatatt
    22861 agcaatgaaa tccttcttaa ttaaaaacgt aaaaggaatg gtcaataaaa tcattaacac
    22921 caaaggagga acaattcgat aaaagcgtct ttttaaaaaa ccgataatat cgatagactc
    22981 tttttttgtg tattcatcaa tcaagagggc tgtgattaga tatcctgaaa aggtgaagaa
    23041 aatatcaaca ccaataaaac ctcctggaaa tacattttta aaaaagtggt agagtaaaac
    23101 cagtaaaagt cctgttaccc taacaaacga aaaccatttt attctcattt ttgaaatatc
    23161 ccctgtttaa aaatcccttt atagacttta ttattctttg cttttaacac acctttgcca
    23221 tttgcttgtc ctttatgaaa ctccccgtta tataaccagc ccgtcttagc agtaaaagtt
    23281 ccttttcctt caaataggcc attcttaaaa gtaccctcat agatatcacc gttggggtag
    23341 acaagcttcc cttctccatt cattttatgg ttgatcacgt aaccagtata gtgcatacgc
    23401 cctttatcat aggtcaaact tgtcttattc gaaattctta cgctaaaaac agaaattgca
    23461 caaaccaata tgacaatcac cgagacaatt tccaacttcg cccgtgtaat actccatttt
    23521 tttactatat cttgcatatc tatcatttct tttactcaac ttctaatatc aatactcttt
    23581 actcattaaa cgagaaagcc aatcctggca tccttttcta actaattggt aggtttcttc
    23641 aaaatcgtta gtgtaccaag gatcaggaac acccccttct ctaaacaggt agattttaga
    23701 gtcccattga tgttgcgaca tctctttgag atttttcaca ttatcgctat ccataccaat
    23761 aatatagtca aaggtgttaa aatcagttat agttatctgc ttggagcatt tagttatatc
    23821 ataattaatt tggtaagttt ttaatatgga ctgtgtacct gagtgaatag ggtttccatg
    23881 ctcccaatca gaagtagcac gactttctat catcataaca tcacttgata ctattgactt
    23941 cattacaaac tcagccatgg ggcttcgaca aatattaccc agacagacaa aacatacttt
    24001 tttcattaaa tactcctttg aattattata tcaaatttct aactgatatc ggagaaatca
    24061 atctaataat tttctgtcaa cttatcaaaa aatccgaaca caaaaagcag gttcagatta
    24121 attttcttag atttgaaaaa tcattaagtg ttttgatagg gatagccaag atgacgataa
    24181 gccttttgag tcgctacacg acctgttcgt gttcgcatga gaaagccttt ttgaattaag
    24241 tagggttcat acatctcttc aactgtatta cgctcctcgg caatattcac agataatgtc
    24301 cccaaaccaa ctggtcctcc ctgatacatc tcaatcatcg ttcgtaaaat tttctgatca
    24361 atgtaatcga gaccttcgcg gtcaacatct aacatagtca aagctctatc agttatttga
    24421 gccgttatga tgccatcacc aataatttga gcatagtcac gcactcgttt tagtaatcga
    24481 ttagcaatgc ggggcgttcc tctactgcga caagctaatt tccgtgcagc ttcatggtct
    24541 atttttattt caaaaatagt agctgtacgc tccacaatct ctgtcaaatc cttttcttga
    24601 tagtattcca tgtgaccagt gataccaaaa cgagctctga ggggattaga taacatgcct
    24661 gcacgtgtag tagcaccaat caatgtaaat ggaggcagat ccaaatgaat actacgacta
    24721 gtatctccag cgccaatcat aatatcaata tagaagtctt ccatagcact atatagtact
    24781 tcctcaacag acattggcat gcggtgaatt tcatcaataa acaaaatatc ccctggttct
    24841 aattcattta aaatagctac caaatctcca gctttctcaa cggcaggacc tgaagtttgc
    24901 tttaaattaa ctcccaattc attggcaatc acaaatgcca ttgttgtttt tcccagtcct
    24961 ggaggtccaa ataataaaac atggtctaaa gattcgtcac gtcttttagc tgcttctata
    25021 aaaatagcga attgttcctt aactttatct tgtccaatat attcgtgtag atattgaggg
    25081 cgaagagtcc gatccgaaaa ctcctcattt cccattacat cattgtctaa aattctagcc
    25141 ataggactat tataacataa agtaaaagag agcagtggcc tacttttatt ataatcgcca
    25201 ccagtcaaca gcactaagct cttgaactac tttaaaagat agtagagctg cgaatataaa
    25261 atagtactta tac
//
LOCUS       DATWEK010000027        23008 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.027, whole genome shotgun sequence.
ACCESSION   DATWEK010000027 DATWEK010000000
VERSION     DATWEK010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23008
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.027"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            178..2010
                     /gene="lepA"
                     /locus_tag="VCR92_001297"
     CDS             178..2010
                     /gene="lepA"
                     /locus_tag="VCR92_001297"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEP4268364.1"
                     /translation="MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQ
                     VRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVAD
                     TRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIE
                     VSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFI
                     VHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDAKK"
     gene            2451..3497
                     /locus_tag="VCR92_001298"
     CDS             2451..3497
                     /locus_tag="VCR92_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEP4268365.1"
                     /translation="MTKLLTYLQEREQAENSWRKRLLKGIQDHALDGQDGRNGERGEQ
                     GPTGPTGPAGPRGLQGLQGERGEQGPTGLAGKAGEAGAKGETGPAGPQGPRGEQGPQG
                     LPGKDGEAGAQGPAGPMGPAGERGEKGEPGTQGAKGDRGETGPVGPRGERGEAGPAGK
                     DGERGPVGPAGKDGQNGQDGLPGKDGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKD
                     GQDGKDGLPGKDGKDGLPGKDGKDGQPGKPAPKTPEVPQKPDTAPHTPKTPQIPGQSK
                     DVTPAPQNPSNRGLNKPQTQGGNQLAKTPAAHDTHRQLPATGETTNPFFTAAAVAIMT
                     TAGVVAVAKRQENN"
     gene            3683..4120
                     /gene="msrB"
                     /locus_tag="VCR92_001299"
     CDS             3683..4120
                     /gene="msrB"
                     /locus_tag="VCR92_001299"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEP4268366.1"
                     /translation="METSDELKQRIGDLSYEVTQHAATESPFTGEYDNFFEKGIYVDI
                     VSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHV
                     FSDGPKEAGGLRYCINSAALKFIPYEQMEKEGYAQWLTLFDET"
     gene            4250..5269
                     /locus_tag="VCR92_001300"
     CDS             4250..5269
                     /locus_tag="VCR92_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEP4268367.1"
                     /translation="MSTHLRKLPGLLLCLLLALPAWYLGRLFPIIGAPVFAILLGMLL
                     ALFYHHRDKAKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALL
                     VAYGSQKWLRLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNML
                     AALLFPSLGQLLGLSNDGFATFAGTAVNDTSSVTATATAWDALHHSNTLDDATIVKLT
                     RTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSFGVS
                     ADVFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQL
                     SLGIW"
     gene            5476..5901
                     /locus_tag="VCR92_001301"
     CDS             5476..5901
                     /locus_tag="VCR92_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEP4268368.1"
                     /translation="MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYT
                     SQIDNFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLV
                     FLKPGEALTKDDIVTVINESQVQLVDLVPETNSEDDFFD"
     gene            5920..6411
                     /locus_tag="VCR92_001302"
     CDS             5920..6411
                     /locus_tag="VCR92_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEP4268369.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKLFNDPRAKDKRIFVIVNSVKDACAIAKEVPDLEAVN
                     VANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQ
                     LVN"
     gene            6428..7237
                     /locus_tag="VCR92_001303"
     CDS             6428..7237
                     /locus_tag="VCR92_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEP4268370.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA"
     gene            7234..8061
                     /locus_tag="VCR92_001304"
     CDS             7234..8061
                     /locus_tag="VCR92_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEP4268371.1"
                     /translation="MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC"
     gene            8197..9846
                     /locus_tag="VCR92_001305"
     CDS             8197..9846
                     /locus_tag="VCR92_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP4268372.1"
                     /translation="MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAP
                     QQLGLYRDINATATRYHRLISKQEALLDDLGKNSLLPFLNKNLSTADLSKHYFHLRHS
                     SQTSPELLLFSPSQDLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGH
                     YLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIAS
                     SLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVI
                     FVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQ
                     MVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIV
                     IQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPK
                     LFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLE
                     AGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE"
     gene            9850..10638
                     /locus_tag="VCR92_001306"
     CDS             9850..10638
                     /locus_tag="VCR92_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP4268373.1"
                     /translation="MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLI
                     KESQPDIVLTDINMPIMTAFDMFEATKDQTYAKIILSGYADFPNARSAIHYGVLEFLT
                     KPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAH
                     FQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVY
                     EIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC"
     gene            10632..11678
                     /locus_tag="VCR92_001307"
     CDS             10632..11678
                     /locus_tag="VCR92_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEP4268374.1"
                     /translation="MLKLKRKWLLSFLLVIIILAIVNIAMYIFSSSKKDSAKELVILT
                     PNSQTILTGTIPAFEEKYGVKVRLIQGGTGQLIDQLGRKDKPLNADIFFGGNYTQFES
                     HKDLFESYVSPQVSTVISDYQLPSHRATPYTINGSVLIVNNELARGLHITSYEDLLQP
                     ALKGKIAFADPNSSSSAFSQLTNILLAKGGYTSSEAWEYVKRLLLSMNSIRATSSSDV
                     YESVAEGKMIVGLTYEDPCINLQKSGANVSIVYPDEGTVFVPSSVAIIKKAKAMKEAK
                     QFINFILSSDVQNAFGQSTSNRPIRRDAQTSHEMKPLDEIITLKEDYGYVTRHKKKIL
                     NTYNRLHEALERGK"
     gene            11791..13188
                     /locus_tag="VCR92_001308"
     CDS             11791..13188
                     /locus_tag="VCR92_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HEP4268375.1"
                     /translation="MAYQTIYPYTNEVLHTFDNMTDQDLADVLERAHLLYKKWRKEDH
                     LEERKAQLHQVANILRRDRDKYAEIMTKDMGKLFTEAQGEVDLCADIADYYADKADEF
                     LMSTPLETDSGQAYYLKQSTGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASIC
                     PRSAQSFEELVLEAGAEAGSITNLFISYDQVSQVIADKRVVGVCLTGSERGGASIAEE
                     AGKNLKKTTLELGGDDAFIILDDADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDY
                     DRFKELLTKVFKTAKWGDPMDPETTLAPLSSAQAKADVLDQIKLALDHGAELVYGGEA
                     IDHPGHFVMPTIIAGLTKDNPIYYQEIFGPVGEIYKVSSEEEAIEVANDSNYGLGGTI
                     FSSNQEHAKAVAAKIETGMSFINSGWTSLPELPFGGVKHSGYGRELSELGFTSFVNEH
                     LIYIPNKTNNSNTKV"
     gene            13290..15086
                     /gene="uvrC"
                     /locus_tag="VCR92_001309"
     CDS             13290..15086
                     /gene="uvrC"
                     /locus_tag="VCR92_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEP4268376.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSY
                     FRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFL
                     KITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCF
                     YYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNL
                     FPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKK
                     QLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLKIDKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLI
                     IVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVPLPRRSEEF
                     FLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASA
                     TSEEIQALGIPKTVVEAIQQQITDNKNDRSSP"
     gene            15271..15873
                     /locus_tag="VCR92_001310"
     CDS             15271..15873
                     /locus_tag="VCR92_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEP4268377.1"
                     /translation="MKFLELNKKRHAIKTFNDQPVDYEDLRTAIEIATLAPSANNIQP
                     WKFVVVQEKKAELAKGLPLANKVQVEQAQYVVALFSDTDLALRSRKIARIGVKSLPDD
                     LIGYYMETLPPRFAAFNEVQTGEYLAINAGIVAMNLVLSLTDQKIASNIILGFDKSTT
                     NEILDIDPRFRPELLITVGYSDEKPEPSYRLPVDEVIERR"
     gene            15998..17407
                     /gene="pepV"
                     /locus_tag="VCR92_001311"
     CDS             15998..17407
                     /gene="pepV"
                     /locus_tag="VCR92_001311"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEP4268378.1"
                     /translation="MTTIDFKAEVDKRKEAMLADLVDLLRINSERDDRSADDQHPFGP
                     GPVKALEHFLAMAERDGYKTRNIDNYAGDFEFGQGDEVLGIFGHLDVVPAGSGWDTDP
                     YEPVIKDDRIYARGSSDDKGPTMACYYALKIIKELGLPVSKKVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFAGDNKGAFVLHRFQGGLREN
                     MVPESATAVITAPHDLDVLEAALEQFLSEYGVKGSMKATDGKIEVTIIGKSAHGSTPE
                     AGINGATLLAKFLNQFTFEGAAKDYLHVAGEVLHEDFAAEKLGLAYTDDRMGALSMNA
                     GVFNFDSQSADNTIALNFRYPKGTDAATLKSGLEKLPGLTKVSLSEHEHTPHYVPMDD
                     ELVATLLAVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     ENIYRSAAIYAEAIYELIK"
     gene            complement(17475..18851)
                     /gene="mnmE"
                     /locus_tag="VCR92_001312"
     CDS             complement(17475..18851)
                     /gene="mnmE"
                     /locus_tag="VCR92_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEP4268379.1"
                     /translation="MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKN
                     LEQVASHTINYGHIIDPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNEIL
                     QLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTIAVKQLDGSLS
                     QLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREKTQEFQSLLENLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDRALLNLSQGSNRI
                     ILLNKTDLEQKIELEQLPADLISISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLS
                     NARHISLIEKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     misc_feature    19021..19156
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            19185..19685
                     /locus_tag="VCR92_001313"
     CDS             19185..19685
                     /locus_tag="VCR92_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEP4268380.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAASIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDVFVGPSAVAFSNEDVIAPAKVINDFTK
                     TADALEIKGGAIEGAVSSKEEIQALATLPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     NKEGAA"
     gene            19750..20115
                     /gene="rplL"
                     /locus_tag="VCR92_001314"
     CDS             19750..20115
                     /gene="rplL"
                     /locus_tag="VCR92_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEP4268381.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAAAAA
                     GGAEEAAKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANVKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            20374..20973
                     /locus_tag="VCR92_001315"
                     /pseudo
     CDS             20374..20973
                     /locus_tag="VCR92_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein"
     gene            21148..21473
                     /locus_tag="VCR92_001316"
                     /pseudo
     CDS             21148..21473
                     /locus_tag="VCR92_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670032.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            21464..21738
                     /locus_tag="VCR92_001317"
                     /pseudo
     CDS             21464..21738
                     /locus_tag="VCR92_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001883480.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            21784..21996
                     /locus_tag="VCR92_001318"
     CDS             21784..21996
                     /locus_tag="VCR92_001318"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268382.1"
                     /translation="MMTDRVMKKPIRGRQLSKRDLYDEEFFRTHFAKIEIESRLEFLL
                     NRANSLEELLLKAKEVNLTIDLKQKM"
     gene            22261..22958
                     /locus_tag="VCR92_001319"
                     /pseudo
     CDS             22261..22958
                     /locus_tag="VCR92_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984809.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic (srt) production protein"
BASE COUNT         7212 a         4121 c         4925 g         6750 t
ORIGIN      
        1 agaggctaag cagatgattg atttaaaaag gaatcttttc aaaattgatg tccgggcaca
       61 aaaggatgaa gagaaagttt tcatgcgtac ggcgtggata atccgtaaga aaagataggc
      121 aaaggcctac cttttttgtt ataatagaag gaaagactaa atgtatagga aaatagaatg
      181 aacagtcaag atttaaaaaa acgtcaggag aagattcgta atttctccat tattgcacat
      241 attgaccatg gcaaatctac tctcgctgac cgtattttgg aaaagacaga gacggtttcg
      301 tctcgtgaaa tgcaggctca gttattggac tccatggatt tggagcgtga gcgtgggatt
      361 accatcaagt taaacgccat tgagcttaat tacacggcta aagatgggga aacctacatt
      421 ttccacctta ttgatacccc agggcatgtg gactttactt atgaagtatc gcgttcgttg
      481 gcagcctgtg agggagcgat tctagttgtg gatgcagcgc agggcattga agcacagacc
      541 cttgccaatg tttacctagc ccttgataat gatttggaaa ttttaccggt tatcaataaa
      601 attgacttgc ctgctgctga ccctgagaga gtccgccatg aagtagaaga tgtcattgga
      661 cttgatgctt ctgaggctgt tctggcgtca gccaaggctg gtattgggat cgaagagatt
      721 cttgagcaaa ttgttgagaa ggttcctgct cctacgggtg atgtggatgc gcctttacag
      781 gccttgattt ttgactctgt gtatgatgct taccgagggg taattttgca ggttcggatt
      841 gtgaacggta ttgtcaagcc tggcgataaa atccagatga tgtcgaatgg aaaaaccttt
      901 gatgttacag aagttgggat tttcactcct aaggcagttg gacgagattt ccttgcgacg
      961 ggagatgttg gttatgttgc ggcctctatc aaaacggtag cagatacccg tgtgggcgat
     1021 acggtgactt tagctaataa ccctgctaag gaagccttgc atggctacaa gcagatgaac
     1081 ccgatggtct ttgcagggat ttatccgatt gaatcaaata aatacaatga cttgcgtgaa
     1141 gcgcttgaaa aattacaact gaacgatgcc agtttacagt ttgaacccga aacgtcacaa
     1201 gcgcttggct ttggttttcg atgcggtttt ttaggcttgc ttcacatgga tgtgattcaa
     1261 gaacgtttgg aacgtgaatt taacattgat ttgatcatga cagcaccgtc cgtggtgtat
     1321 cacgttcaca caacagatga ggacatgatt gaagtgtcta acccttcaga atttccagat
     1381 ccaacacggg tggcttttat tgaagagcct tatgttaaag cgcaaatcat ggtgccacaa
     1441 gagttcgtag gggctgttat ggaattatcg cagcgcaagc gtggtgattt tgtgaccatg
     1501 gattacattg atgataaccg tgtcaatgtg atctaccaaa tcccgctggc tgaaattgtc
     1561 tttgatttct ttgataaatt gaaatcctca acgcgaggct atgcgagttt tgattatgac
     1621 atgtcagaat accgcaggtc acaattggtg aaaatggaca ttcttttgaa cggtgataag
     1681 gtcgatgcgc tcagctttat tgttcataaa gaatttgctt atgaacgcgg gaaaattatt
     1741 gttgagaaat tgaaaaaaat cattccacgt caacagtttg aagtgcctat tcaagccgct
     1801 attggtcaaa aaattgttgc gcgttcagac atcaaggccc ttcgtaaaaa cgttttagcg
     1861 aagtgttatg gtggtgacgt gtctcgtaaa cgtaaattgc tcgaaaaaca aaaggctggt
     1921 aaaaaacgga tgaaggctat tggttctgtt gaagtccctc aagaagcctt cttgagtgtt
     1981 ctttcaatgg atgacgatgc caagaaataa ccaagcctaa tcgcttagtc ttcagaggag
     2041 aactcttgtg ggtctacatg accaaaaaat ggttatctta tacaaaaaga actttacaat
     2101 catttgcaca taatgttata ataatattat agtgttatct cattattagg tgcgcctgca
     2161 tttaatctta ttaaacagaa agaggaaaca aaaactgtga acaaaacaaa acaaaacaaa
     2221 acaaaacaaa acaaaacaaa acaaaacata gccttctttg tcgctatggc ttaacctcag
     2281 cggctgctct tttgctgacc tttggaggtg caagtgcagt taaggcggat gaacaagaag
     2341 agaaagctaa agttagaact gaattaattc aagagttagc tcagggacta gggggtattg
     2401 agaaaaaaaa ttttccaact ctaggtgatg aagatttaga tcatacttat atgacaaagc
     2461 tattaacata cctacaggaa cgagaacaag ctgagaatag ttggcgaaaa agactactaa
     2521 agggtataca agatcatgcc cttgatggac aagacggtcg aaacggtgaa agaggggaac
     2581 aaggaccaac aggtccaacc ggacctgctg gtccacgagg tctacaaggt ctacaaggtg
     2641 aaagagggga acaaggacca acaggtctcg ctggtaaagc cggtgaagct ggagccaaag
     2701 gcgaaaccgg ccccgctggt ccacagggtc cacgtggtga acaaggcccg caaggtcttc
     2761 caggtaaaga tggtgaagct ggtgctcaag gcccagcagg tccaatgggt cctgctggtg
     2821 agcgaggtga aaaaggagaa cctggtaccc aaggcgctaa aggtgatcgc ggtgaaaccg
     2881 gtccagtagg tccacgtggt gagcgaggcg aagccggtcc cgctggaaaa gatggtgaac
     2941 gtggtccagt aggtccagct ggtaaggacg gccaaaacgg ccaagatggt cttccaggta
     3001 aagacggtaa ggacggccaa aacggtaaag atggtcttcc aggtaaagac ggtaaggacg
     3061 gccaaaacgg taaagatggt cttccaggta aagacggtaa ggacggtcaa gatggtaaag
     3121 acggcctccc aggtaaagac ggtaaagatg gcctcccagg taaggacggt aaggacggtc
     3181 aaccaggtaa accggctcct aaaacaccag aggtccctca aaaaccagat accgcaccac
     3241 atacaccaaa aacccctcag atccctggcc aatcaaaaga cgtgacacct gcccctcaaa
     3301 acccttctaa tagaggtcta aacaaaccac aaacacaagg tggtaatcag ctcgcaaaaa
     3361 caccagcagc tcacgacaca cacagacaat tgccagcaac aggcgaaaca accaatccat
     3421 tctttacagc agctgctgta gctatcatga cgacagctgg agttgtagct gttgcaaaac
     3481 gtcaagaaaa caactaatcc tctttttgct acctaactga tggaaagtaa aactcagaga
     3541 gaacctcaag gttctctctt ttttgaatca agatagtagc tctaggtata acgtcttgtc
     3601 tgaggtgctg tgaacaaatc agttaccact cacctctttt tttggtaaaa tgtaagcact
     3661 aagacatcaa aaggagtttt ccatggaaac atcagatgag ttaaaacaac gcattggtga
     3721 tctttcttac gaggtcaccc agcatgcagc aacagaatct ccctttacag gcgaatatga
     3781 taattttttt gagaagggta tctatgtcga tattgttagt ggtgaggtct tattttcatc
     3841 actggataaa tttaattctg gctgtggttg gcctgccttt tcaaaaccca ttgaaaatcg
     3901 tatggtcaca aaccacgatg actcttctta tgggatgaga cgagttgagg ttaaaagccg
     3961 tgaagcagga tcgcatttgg ggcatgtctt tagtgacggc cccaaagaag ctggaggctt
     4021 gcgttactgt atcaattcag cagctcttaa attcattcct tatgagcaga tggaaaaaga
     4081 aggctatgcc cagtggctca cattgtttga tgagacataa ccgggtttca aaatgactga
     4141 aaaagaagcg tcagtgattc ccacaagcac tggattggtg aggcgtacgg gtcaatttta
     4201 caagcctttg taaaaggtct ataataggga atgaaaaaag gaggttagta tgtcaactca
     4261 cttaagaaaa cttccagggc tgttactttg cttgttgtta gctcttccag cctggtattt
     4321 agggcgctta tttcccatta ttggagcacc tgtttttgct attcttttag gaatgttgtt
     4381 agccttgttt tatcaccatc gtgacaaggc taaagaggga attagtttta catccaagta
     4441 tattttacaa acagcagttg ttttgcttgg ttttggatta aacctaaccc aagttatggc
     4501 agtgggcatg cagtctttac cgattatcat ttcaactatt gcgacagctc ttttggtagc
     4561 ttatggctca cagaaatggc tgcgcttaga tgtcaataca gccaccttgg tgggtgtagg
     4621 gtcttccatt tgtggggggt ctgctattgc agcgacggct cctgtcatta aggcaaagga
     4681 tgatgaggtt gctaaggcaa tttcagtcat ttttctcttt aatatgttag cagctttgct
     4741 atttccaagt ttaggacaat tactgggctt atctaatgat ggttttgcta cttttgctgg
     4801 gacagctgtt aacgacacct cttccgtgac tgcaacggcc acggcctggg atgcccttca
     4861 ccattccaat acactagatg acgcaaccat tgtcaaattg actcgcacct tggctattct
     4921 tccaattact ttaggtttat ccctttaccg agcgaaaaaa gagcacgaca tcgttacaga
     4981 agaaaacttt agccttagga agtcattccc tcgtttcatc ctcttctttt tattagcttc
     5041 cctcatcacg acattgatga ccagctttgg tgtttctgcc gatgttttcc attccctaaa
     5101 aaccttatca aaattcttta tcgtgatggc tatggcggct atcggtttaa atacaaacct
     5161 ggttaaatta atcaagacgg gcggtcaggc tatcctttta ggagctattt gctgggtagc
     5221 tatcaccctt gtcagtttag ccatgcaatt aagtttgggc atttggtaat cagacacgag
     5281 aaatcagttt gactgatttc tttttttgta tcttatttgt gtagaattgt ctacatttta
     5341 aagagaatag tgcattttaa aaacgttttc atttgataaa ataaacctat cgttaaacca
     5401 gttcagtaaa gacaactggt tgagataagc aattaccgtt tattcagcgg tttttgttaa
     5461 tagaggagga taggaatgaa acgaaaattt ctcattggga gtcacggcag actagccagt
     5521 ggtttgcaaa gctctattga cattttagca ggtatgggac aggcacttga aaccattgat
     5581 gcttatgttg atgatagtga ctacactagc cagattgata actttatcgc tggggtagca
     5641 gcagatgagc agggccttat ttttacagat ttgttaggcg gcagtgtgaa tcagaaaatg
     5701 gtaaccgctg taatgaacag tggcaaagac aatatctttt taatcacaaa cagtaactta
     5761 gccactttat tgtcgttggt gtttttaaaa ccaggcgaag cgcttactaa agatgatatt
     5821 gtaaccgtta tcaatgaatc gcaagttcag ttagtggatt tggtccctga gacaaattca
     5881 gaagatgact tttttgatta atatctagga ggaagacaaa tgattactca aattcgtgtt
     5941 gacgaccgtt tgattcacgg gcaagtggca gttgtatgga ccaaagagtt aaatgcgcca
     6001 cttttagtag tggctaatga tgaagctgca aagaatgaaa tcacacaaat gacgcttaaa
     6061 atggctgtgc caaacggcat gaaactgctt attcgttcag ttgaagactc gattaagctc
     6121 tttaatgatc cacgcgccaa agacaagcgt atttttgtga ttgtcaattc tgttaaagat
     6181 gcttgtgcca ttgctaaaga agttccagac ttagaagctg ttaatgtggc taacgtgggg
     6241 cgttttgaca aatcagaccc agcaagcaaa gtcaaagtga caccaagtct tttacttaac
     6301 ccagaagaaa tggcagccgc aaaggaatta gtcagtttac cagaacttga tgtctttaac
     6361 caagtcttac catcaaatac caaggtccat ttgagccaat tagtcaacta aagagaggta
     6421 aaaaagtatg ttagtaccag caacaatggc agctttagct gtattgattt gttttggggg
     6481 aaattattta accggtcaaa gcatgatgga aagaccccta gtagttggac tggtcacagg
     6541 tcttctttta ggagatatga aggtcggtat cttaatgggg gcctctctag aagctctttt
     6601 cctaggaaat gtgaatattg ggggtgttat tgcagctgag cctgtaacag cgactgccat
     6661 ggcaacaacc tttaccatta tttcacatat tgaccaaaaa gcagccatga ccctagctgt
     6721 tccaattgga atgttggcag cctttgtggt tatgtttttg aaaaacgtct tcatgaatat
     6781 ctttgctcca atggttgata aagctgcagc agctaaccat caaggtaaac tagtgatgct
     6841 ccactatggc acttggatta tctattactt gatcattgcc tctatttctt tcattggtat
     6901 tttagtaggt agtggacctg ttaatgcctt tgtggaacac attcctcaaa atctcatgaa
     6961 tggcttgagt gctgcgggag gccttcttcc agctgtcggt tttgccatgc tgatgaaatt
     7021 attgtggacc aacaaattag ctgtttttta cctattgggc tttgtcttaa cagcttattt
     7081 gaaattacca gcggttgcag ttgctgccct aggagcagtt atttgcgtca ttagttccca
     7141 acgtgatcta gaattagacg caattactag aggtgcaatt agtaaacaaa caacctttga
     7201 ctctaaagaa tcagaagagg aggacttctt cgcatgacat cacaagataa tttgactaaa
     7261 gaagaccgta aaatgcttcg ctcagtcttt tggcgctcat ggacgatgaa tgctagtcgt
     7321 actggggcaa cacaatacca cgcagtaggg gttatttaca ctttactacc agtcatcaat
     7381 cgtttttata agactgataa ggataaagca gaggcactgg tccgtcatac aacatggttc
     7441 aatgccacca tgcacatcaa taactttatc atgggtcttg tggcatcgat ggaaaagaaa
     7501 aacagtgaag atcctgattt tgatgctagt gctatcaccg ctgttaaggc ttcgttgatg
     7561 ggacctatat ctggagttgg agattccttc ttctggggaa ttttaagggt tattgcggca
     7621 ggtatcggga tttccttggc aagtgcaggc tcagccatgg gagctgttgt cttcttactc
     7681 ttgtacaata ttcctgcttt tattattcac tactatagcc tttatggtgg ttattctgta
     7741 ggtgcaggat ttatcaaaaa actttacgaa tctggtggta taaaaatcgt cactaaaacc
     7801 tcaagcatgc ttgggttaat gatggtaggc tcaatgacgg cttcaaatgt aaaatttaaa
     7861 acgattctta cagttgctgc gaaaggtgcc aaagaagcag cttctattca agattacctt
     7921 gaccaattgt ttattggtat tgtaccatta atggtaacac tagcagcttt ttggcttcta
     7981 cgaaagaaag tgaatatcaa ctggattatg tttggtatca tgttccttgg cattatcctt
     8041 ggacttttag gtatttgcta ataatctcct agcaataaag gtaagtaaga caagttttct
     8101 tgttttgctt acctttttcc ttttaagatg atgagacttg ttttgatgaa aaacgtagta
     8161 gcattaagaa atttgttata atgaaaggag cttaagatgc gaggtgaaca ggtggaagaa
     8221 cattttaaaa aacaattaca agatgatatt tctagacatt tttcgtacca atcgttaatg
     8281 ttatcattgt tgctaattgg tctttttatt attttttcat tagcgccaca acaattaggc
     8341 ctctatcgtg atatcaatgc cactgcaacc cgttatcacc gtttgattag caaacaagaa
     8401 gccttgcttg atgacttagg gaaaaatagc ttactacctt ttttaaataa aaacctcagc
     8461 actgctgatt taagcaagca ctattttcat ttgcgccata gcagccaaac gtcaccagaa
     8521 cttttactat tttcacctag tcaagacctt ttatttgcta gtaacccaca tttaggaaat
     8581 gtttttagta aatctgttta tattcaagaa gtcttgagag cagctcatcc tccaaaaacc
     8641 ttgtttaaag ttgctatgga tagtgaagat ggtcactact tgatgatcat taagccaatg
     8701 attgatcaaa accaactaaa gggatatgct tttttagtga tgagtggcaa agattttctt
     8761 catcctacaa aaacactgac gtcagagttg gtcattgctg ataagctgga caatacgttt
     8821 acgttttcca atcgtgagtt tatagcatct agtctagata agatcaacag tcagtattta
     8881 caccattatt ttgtttttca agataatcga gcctttatca caagaaaggt tgccttacaa
     8941 ggaggtcttt ggctttacat gtataggccc ttgattccaa tggtatcggt gatgttattt
     9001 tcacttattt catcagctgt tatctttgtg atcttgcaac gtaaatcaag tggtttagct
     9061 aaccgaattg cagctaaaaa ttcaagagca atcaatcaaa tggttagaga tatgagtgcg
     9121 atctctcggc aagaaaaaag acgtattgac cttgagagtc aagatgaatt tcaatattta
     9181 tctgatcaaa tcaatcaaat ggtagagcga ttgcaacagt tacatgataa aacgttagat
     9241 ttggaaactc aaaaattatt atttgaaaaa cggatgttag aagctcaatt caatccgcat
     9301 ttcctctaca atacgctaga aaccattttg attacgagcc attatgattc tgccctaaca
     9361 gaaaaaattg ttatccaatt gacaaaattg ttgcggtata gtctcacgga ttctagcaaa
     9421 cctgtcttgc tcaaagatga tttaagtgtc atcgagtctt atttagtgat taatcaggtg
     9481 cggtttgaag aattgcaata tagcattaac ctatccccag accttgatag tcttgcagtg
     9541 cctaaattgt tcttgttacc tttgatagaa aatgccatca aatatggctt gaaagaacga
     9601 cacgatgtca agattaacat tgcttgttat tatcaagatg accatattat tttttctgtg
     9661 cgagataatg gttcgggaat tgatgctcat caccaaaaag tgattcgaga gcaattggaa
     9721 gctggagagt cacaccatgg gttaattaac tcttatcgtc gacttaagta tcatttttca
     9781 gaagtatcct tggtttttga tcaaggtgat aaacagttta atgttagcta ccatgttaag
     9841 gagtagtcta tgtacaaatt agtcattatt gaagatgaac atattattag gaaatggttg
     9901 cgatacgcta ttgattataa agctttagat attttggtca ttggcgaggc taaagatggc
     9961 aaagaaggag ctgttttaat caaagagagt caaccagata tcgttttaac tgatattaac
    10021 atgcccatca tgacagcttt tgacatgttt gaagcaacaa aagatcaaac ttacgccaaa
    10081 attattttat ctggctatgc cgattttcca aatgcaagat ctgctataca ctacggtgta
    10141 cttgaatttt taacaaaacc gattgaaaaa gcagctcttt gggaatgtct tcaaaccatt
    10201 attgctaaaa tagaaaagca aaaggggtct aatcaaaaaa cagatgcttg cgtctatatt
    10261 cccttacccc agatgactga tcagattcct gaagtagtca aagatatttt ggagtgggta
    10321 catgctcatt ttcaagacaa gatcagcacg agccgcctag ctcatgactt agggtatagt
    10381 gagagttata tctatcaaaa tatcaaaaag catcttcaga tgcctttaag tgattacatt
    10441 aatcaatatc ggattaatca ggcaattcaa ttgatgcaac aagaaccaga tttaatggta
    10501 tatgaaatag cacaagctgt aggtatttat gactatcgct attttgatag ggtttttaaa
    10561 aagtatctag gacaaactgt aaaggctttt aaagaagagc attttatgaa ggataccgat
    10621 aggagtaagc catgttaaaa ctcaaacgca aatggctatt aagctttttg ttagtaataa
    10681 ttattctagc aatcgttaac attgcaatgt atatattctc atcgtcaaaa aaagatagtg
    10741 ctaaagaatt agttatcttg actcctaata gccaaactat tttaacaggg actattccag
    10801 cctttgagga aaagtatggg gttaaagtaa gattaatcca aggtgggacg ggccaactta
    10861 ttgatcaatt aggtcgaaaa gataagccat taaacgctga tattttcttt ggtggcaatt
    10921 acactcaatt tgaaagccat aaagatttat ttgaatccta tgtttctccg caggtttcta
    10981 ctgtcatttc agattaccaa ttgcctagtc atcgtgcaac cccatatacg atcaatggca
    11041 gtgtactgat tgttaataac gaattagcaa gaggacttca tattaccagt tatgaggatt
    11101 tgctacaacc agctttaaaa ggcaaaattg cttttgctga cccaaatagc tcatctagcg
    11161 ctttttcaca attaacaaac atcttactgg ctaaaggagg ctatacgagc tcagaagctt
    11221 gggagtatgt gaaacgttta ttactgtcta tgaattctat cagagcaaca agttcttcag
    11281 atgtttacga atctgttgca gaaggtaaaa tgattgttgg tttgacctat gaagaccctt
    11341 gcatcaatct gcaaaaaagc ggtgcaaacg tttcgattgt ttatccggat gaggggacag
    11401 tatttgttcc gtcatcagtc gctattatca aaaaagcaaa ggcaatgaaa gaagctaagc
    11461 aatttattaa ttttatttta tcatcagatg tacaaaatgc ctttgggcag tcaactagta
    11521 atagacctat ccgacgagat gctcaaacga gtcatgaaat gaaaccatta gatgaaatta
    11581 ttactttaaa agaagattac ggatatgtta ctagacataa gaaaaaaata ttgaatacct
    11641 ataatcgact acatgaagca ttagaaagag gaaagtagac tctaggcttg ttgttgctat
    11701 actagtagtg ttacaaaata gcgtagtcat tttttgaaat cgatttcata atctggtaga
    11761 ctaagattat cacgaaaagg agataatata atggcttatc aaactattta cccttataca
    11821 aatgaagtcc ttcatacatt tgataatatg accgatcaag atttggcaga tgtccttgaa
    11881 agagctcacc ttctctataa aaaatggcgc aaggaagatc atttagaaga acgtaaagcc
    11941 cagcttcatc aagtggctaa tattcttcgc cgtgaccgcg ataaatatgc tgaaatcatg
    12001 accaaagaca tgggaaaact gttcacagaa gcccaaggtg aagtagatct ttgtgccgat
    12061 attgctgatt actacgctga taaggcagat gaatttttga tgtctacgcc actagaaaca
    12121 gattcaggtc aagcttacta tttgaaacaa tcaactggtg ttattctagc tgttgaacct
    12181 tggaatttcc cttactatca aatcatgcgg gtctttgcgc caaactttat tgttggaaac
    12241 ccaatggttt taaaacacgc ttctatttgc ccacgatctg cccaatcctt tgaagaatta
    12301 gttcttgaag ctggtgctga agcaggtagt attaccaatt tgtttatttc ttatgaccaa
    12361 gtatcacaag tgattgctga taaacgtgtg gttggtgtct gcttgacagg ttccgaacgt
    12421 ggaggagcta gcattgcaga agaagctggt aaaaacttga aaaaaacaac ccttgaattg
    12481 ggtggcgatg atgcctttat tatccttgat gacgcggatt gggatcaatt agagaaggtg
    12541 ctttacttct ctcgtctcta caatgcaggt caagtatgta cctcatcgaa acgttttatc
    12601 gtgcttgaca aagactatga ccgtttcaaa gagttattaa caaaagtctt caaaacagct
    12661 aaatggggtg atccaatgga tcccgaaacg acgttggcgc cattatcatc agctcaagct
    12721 aaagcagatg ttcttgacca aattaagttg gccttggatc atggtgcgga gttggtttat
    12781 ggtggtgaag cgattgatca tccaggtcat tttgtcatgc caaccattat tgctggcctc
    12841 acaaaagaca accctattta ctatcaagaa atctttggcc cagtcggtga aatctacaaa
    12901 gtgtcttctg aagaagaagc gattgaagtg gcgaatgatt ctaactatgg ccttggaggt
    12961 actatcttta gtagcaatca agaacatgcg aaagccgtag ctgctaaaat tgaaactggt
    13021 atgtctttta tcaactcagg ctggacaagt cttccggaac tcccatttgg tggggttaaa
    13081 cattcaggct atggccgtga attgagtgag cttggcttta catcttttgt gaatgaacac
    13141 cttatctata ttccgaataa aacgaataat agcaatacta aagtttgatc tagattgtta
    13201 aagaagagtg taacgcctta ataaacaatc aaggcgttac actcttcttt tttaaagtca
    13261 aaattttaaa aatttgataa actagtaaca tgaacgaact gattaaacat aaactagaac
    13321 tcttaccaga cagccctggc tgttacttac ataaagataa agaaggaact attatctatg
    13381 tcggtaaggc taagaatttg aaaaaacgcg tccggtccta ttttcgtggg agccatgata
    13441 ccaaaacaga gttactagta tctgagattg tagatttcga atatattgta acagagtcag
    13501 ataccgaagc gcttttgttg gaaattaact tgattcaaaa aaatatgcct aagtacaaca
    13561 tcaagttaaa agatgataaa tcttatccct ttctcaaaat cacaaatgag tcttttcctc
    13621 ggttagtgat tacaagatat attaagaaaa atgatggatt gtactttggg ccctacccag
    13681 attcttacac tgctaatgaa gttaaaaagt tattagatag gatttttcca tttaaaaagt
    13741 gtaaaaatcc tatcaataag gtctgttttt attaccattt aggccagtgc tgtgctcata
    13801 ccatttgtca tacagacaag gcctattggg atcgtttaat tgatgatgtt aagcactttt
    13861 taaatggtaa agatgacaaa attattgaag atcttcgttc taagatgtta gcagcttctg
    13921 aagaaatggc atttgaacgt gccgctgaat atcgagattt gatttcaggt attgccacca
    13981 tgcgcaccaa gcagcgggtg atgagcaagg atttgcaaga tagagatatc tttggctatt
    14041 atgttgataa gggatggatg tgtgtccaag ttttctttgt gcgtcaaggg aaattaattc
    14101 agcgtgatgt taaccttttt ccctattata acgatgcaga agaagatttc ttaacttata
    14161 tggggcaatt ttaccaagat aaacagcatt tcatccctaa agaagtcttt attccagaag
    14221 ctattgatga agaactggta gccgctattg tgccaaccaa aatcatcaaa cccaaacgcg
    14281 gtgaaaaaaa acaactggta gctttggcta ctaagaatgc tcgtgttagt ctgcaacaaa
    14341 aatttgattt attagaaaaa gatatcaaaa aaacgagtgg tgctatcgaa aatttaggtc
    14401 agttacttaa gattgacaag cctgtgcgca ttgaagcctt tgataattct aacattcaag
    14461 ggacaagtcc agttgcggct atggttgttt ttgttgatgg caaacctagt aagaaagatt
    14521 atcgtaaatt taagattaaa acagtggtgg gaccagatga ttatgccagt atgagagaag
    14581 tgctttttcg aaggtacagt cgggtgaaaa aggagggact gcaagctcct aacttgatta
    14641 ttgttgatgg aggcgttgga caagtcaatg tggccaaaga tgtgatagaa aaacaacttg
    14701 gactcactat tcctgttgcg ggacttcaaa aaaacgataa gcaccagacc catgatttgc
    14761 tttttggaaa cccacttgaa gttgtaccgt tgccgcgccg ttctgaagag tttttcttac
    14821 tgcatcggat tcaagacgaa gtgcatcgct ttgcagttac atttcataga caagtgcgac
    14881 gtaaaaattc tttttcatca acattagatc atatttcagg gcttggccca aagcgaaaac
    14941 agttattact aagacacttt aaaaccataa cagcgattgc atcagctacc tctgaggaga
    15001 ttcaagcttt aggtatacct aaaacagtag ttgaagcaat acagcaacag ataacagaca
    15061 ataaaaatga tagatcgtct ccttaaataa gtgttatgtt ttcagtactg atgaggtaaa
    15121 aaggcgctac ttgttacgca cgacatttca gttcgttatt ttgaaacttt cagaaagttg
    15181 cgaagtgtag tgagtttatg attttaaaaa ctattttatg gtaaaataaa atggtattaa
    15241 aaaaaacaga tttagatagg aagttttgaa atgaaatttc tagagttaaa caaaaaacgc
    15301 catgccatta agacctttaa tgaccagcca gttgactacg aggatttgcg aacagccatt
    15361 gagattgcaa ccttagcacc tagtgccaat aacattcaac cttggaaatt tgtagtcgtt
    15421 caagagaaaa aagctgagtt agcaaaaggg ttacctctag caaataaagt gcaggttgaa
    15481 caggctcaat atgtagtggc gctattttca gacactgatt tagctttacg ttctcgtaaa
    15541 attgcccgta tcggtgtcaa atcgttacca gacgacttaa ttggttatta tatggagact
    15601 ttgccaccac gttttgctgc ctttaatgag gttcaaaccg gtgagtactt agctattaat
    15661 gcaggcattg tggctatgaa cttggtgtta tccttgacgg atcaaaagat tgcttccaat
    15721 attatccttg gttttgataa gtcaacgacc aatgaaattt tagacatcga tccgcgtttt
    15781 cgtccagaat tattgattac tgttggctat agtgacgaga aaccagaacc aagttatcgt
    15841 ttgcctgttg atgaagtcat cgaaagaaga tagagtcagg acaattagtt aaatgtaatg
    15901 tccagatgcg ctacggagcg accgctattg ttagactgat actattttgg cttattttaa
    15961 gttaaacatt atccctaaaa cgaataagga gagtataatg acaaccattg attttaaagc
    16021 agaagttgac aaacgtaaag aagctatgct agcagattta gttgacctat tacgcattaa
    16081 ttcagaacgc gatgacagat cggccgatga tcagcatccc tttgggccag gtccagttaa
    16141 ggctttggag catttcctcg caatggctga gcgtgatggc tacaaaacgc gtaatattga
    16201 taactatgca ggtgactttg aatttggtca aggtgatgaa gtactaggaa tctttggcca
    16261 ccttgatgtt gtgccagctg gtagcggttg ggatacagac ccttatgagc cagtgattaa
    16321 agacgatcgc atctatgcgc gtgggtcttc ggatgataag ggaccaacca tggcgtgcta
    16381 ctacgctctg aaaatcatta aagaattggg tcttcctgtg tctaaaaaag ttcgtttcat
    16441 tgttggtacc gatgaagaat ctggctgggg ggatatggat tattactttg ctcataatgg
    16501 cttgaaaaat ccagattttg gtttctcacc agatgctgaa tttccaatta tcaatggtga
    16561 gaaaggaaat atcaccgaat acctccattt cgctggtgac aacaagggcg cttttgtgct
    16621 tcatcgcttc caaggtgggt tgcgtgaaaa catggtacca gaatctgcca cagctgtcat
    16681 tacggcaccg catgaccttg atgtgctaga agcagccttg gagcaatttt tatcagaata
    16741 tggtgttaaa ggctctatga aggctactga tggtaaaatt gaagtaacta ttattgggaa
    16801 gtctgctcac gggtcaactc cagaagctgg aatcaatggt gccaccttgc tggctaaatt
    16861 cctgaatcaa tttacctttg aaggggctgc taaagattat ttacatgtgg caggtgaagt
    16921 gcttcatgaa gactttgcgg cagaaaaact aggccttgct tataccgacg accgtatggg
    16981 agccttgagc atgaatgcag gtgtctttaa ctttgatagt caatcagctg acaataccat
    17041 cgccttgaat ttccgttatc caaaagggac tgatgcggca accttaaaat caggattgga
    17101 aaaattacca ggtttaacta aggtaagcct ttctgagcat gaacatacac ctcattatgt
    17161 gccaatggat gatgaattgg tagcaacctt gcttgctgtt tacgaaaaac aaacaggtct
    17221 taaaggctac gaacaagtta tcggcggagg aacctttggt cgtttgctag aacgtggtgt
    17281 ggcctttgga gcaatgttcc caggtgatga aaacactatg caccaagcta atgaatatat
    17341 gcctttagaa aatatttatc gctcagcagc tatttatgct gaagcaatct acgaattaat
    17401 taaataagat gtttatgaca gcaaaaagag ctggaacagt gttccagctc ttttgtgatg
    17461 attagagact gttgttattt accaagacag aattgactaa agagttgggt aatgagctca
    17521 tcaggagcag catcccctgt gatttctccg agaatttccc aagttctggt taaatcaacc
    17581 tgtagtaaat caactggcat gccaagcgcc aagccgtcat tgacagcttc taaactctgg
    17641 actgcctttt caatcaaaga aatgtggcgg gcatttgaca ggtaagtggc atcttgttct
    17701 actagtccag cattatcaaa gaagagctgg ttgatacgat cttcgatcag attaatgttc
    17761 tggttggtta acaccgaaat agaaataagg tccgctggca actgttccaa ttcaatcttt
    17821 tgttccaaat ctgttttatt cagcaatata atgcggttac tgccctgact gagatttaac
    17881 aaagcccggt cttggtcagt cagtttttca gaagcattca gcacaagaag aacaaggtca
    17941 gcttcttgaa gagctttttt agaccgttca actccgattt gttcgaccag atcatctgtc
    18001 tcacgaatac cggccgtatc gacaagtttt agaggaactc ccttgatatt aacgtattct
    18061 tcaatgacat ctcgggtggt tcctgcaata tcagtcacaa tagccttgtc ttctcgcaac
    18121 aaattattaa gtaagcttga cttaccgacg tttggacgac caataatagc tgttgataag
    18181 ccctcacgca gaattttacc gcgtttagct gttcgaagga gattttccaa aaggctttgg
    18241 aattcttgtg ttttttcacg tagcagagca gtggtcattt cttccacatc gtcgtattca
    18301 gggtagtcaa tattaacttc gacttgagct aaggtgttga gaatttcttg tcgggtgtca
    18361 ttgataagct gggaaaggga gccatccagt tgcttgactg caatcgtcat agccttgtct
    18421 gttttggcac gaataatgtc catgacagcc tcagcttgag tcaaatcaac acgaccattt
    18481 aagaaggcac gtttggtgaa ttcgccaggc tctgccattc tagcgccttg gcgaatcaat
    18541 agttgcaaga tttcatttgt cacagcaata ccaccgtgcg tattgatttc aaccacattt
    18601 tcacgggtaa aggttttggg ggctagcatg actgacacca taacttcatc gataatagtt
    18661 cctgtcttag gatcaatgat atggccatag ttaatggtgt gtgaggcgac ttgctctaag
    18721 ttctttccct taaaaacaga ttgtgcaatg gcaagcgcat ctgtcccgga tagacgaaca
    18781 atgccaatag ctccttcacc aagaggggtt gaaatggcgg taattgtatc aaattcttta
    18841 gttatactca tgccctctat tttaaatcaa gtcctagtag aaagcaaggt attattttgt
    18901 atagaaaata ggactagcac cattttgagt ttagctaata ctaaaaaaat aaatgtaaaa
    18961 aaatcatttt tttaataatt tttattgaca atagtattat aaaagaatat aatgatatag
    19021 gttttgataa aaaactgacc taagacagca ggggagcatg ctcataatat tcctgccgag
    19081 gcacaaaacg tgattaaaga aaataacgta tttgtacttt cgtgtctagg tttaggtgcg
    19141 atttttttgt acctagccca aaaataaaaa cggaggtaaa actaatgagt gaagcaatta
    19201 ttgctaaaaa agctgaacaa gtcgaactta ttgctgagaa aatgaaagca gcagcaagta
    19261 tcgttgttgt tgattcacgt ggtcttacag ttgatcaaga tactgttctt cgtcgttcac
    19321 ttcgtgaaag tggcgttgag ttcaaagtta tcaaaaactc aattttgact cgtgcagctg
    19381 aaaaagcagg tcttgatgag ttgaaagatg tattcgtagg accatctgca gtagcatttt
    19441 ctaacgaaga tgttatcgca ccagctaaag ttatcaacga ctttactaaa actgctgacg
    19501 cacttgaaat caaaggtggt gcaatcgaag gcgctgtttc ttcaaaagaa gaaatccaag
    19561 cacttgcaac attgccaaac cgcgaaggaa tgctttctat gcttctttct gtacttcaag
    19621 ctccagtccg caacgttgca tacgctgtca aagctgttgc agaaaacaaa gaaggcgctg
    19681 cttaagacgt ctcagagtag cttaaggcta cgcttaacat tttaaattaa ttatttggag
    19741 gaaatcacaa tggcattgaa cattgaaaac attattgctg aaattaaaga agcttcaatc
    19801 cttgagctta acgatcttgt aaaagctatc gaagaagaat ttggtgtaac tgcagctgct
    19861 cctgtagctg ctgcagctgc tggtggtgct gaagaagctg ctaaagattc attcgacgtt
    19921 gaattgacat ctgctggcga caaaaaagtt ggcgttatca aagctgttcg tgaaatcaca
    19981 ggtcttggtc ttaaagaagc taaaggtctt gttgatggag cacctgctaa cgttaaagaa
    20041 ggcgttgctg ctgcagaagc tgaagaaatc aaagctaaac ttgaagaagc tggagcaaca
    20101 atcactctta aataagaagc agatagcaat ttgagagcga aatcccgatt tatcagtctt
    20161 ttagagctta tagcgatttg aagaaactga taaaatgatt tggttttttg ccaaaaatcc
    20221 tgccaaaaaa atctttggca ggatttttat tttctataaa aattaagctg agtagagtgg
    20281 ttattctatc tatatgtgtc tagtaataat ttttttattt tcaggaggaa aatcatgcaa
    20341 atgaatgaac agtcatcacg acaaatggtg attgccatct atctcattta ttccaactca
    20401 aaatgatagt actccttggc tgttccaagt cgaaattgtt agtgattaag aaaacctacg
    20461 agactatggt ttgatcgatg aaggccagca gtctcccagt gaaaaagggc gtttggctaa
    20521 taagatttat ttaggaaagt tggaacatga tttcacccca gtcttaagtt cagacggggc
    20581 cagtctcaaa aacagaccag ccccgtgtta aattcagccc ctagtgagac tgaaaagagt
    20641 gaaactgaag gtagtgaaac taaagagagt aatttagtca ttgaggacga ggaggaaaga
    20701 aaggagtgca ctagtgtgaa aaagactgag ggtcacttta ctcgtcaagt tgatcatgtc
    20761 accaaatatg acaaagatta tatttggagt ttggttcatt cccaattacg tgaaggtggt
    20821 ttatcacaag ctgctagtga cttagtcatg agctattttg aagaacgcta tgcttatgcg
    20881 ctggaacaca tacggttcgc aagaacagct gaagctattg cggaatatgt ctttaatggt
    20941 gtcttatccg aatggaccaa gcaactaagg tgacaagaag cgaagtgagt aagatgtttt
    21001 ggtggctatt attaggtgtt tggggactaa ggacaatttg gttgattatt gaagttatca
    21061 ctgcaccaga aatggaagat tatagttgag taaggacgtt acataagcag taaggtcctt
    21121 ttattttgtc agaaaggaat gagagatatg cagtttttag atttgtttgc aggaattgga
    21181 ggctttcgat tgggtttaat taatcagtgc catgagtgta ttggcttttg tgagattgat
    21241 aagtttgcga ggcaatctta caaagccatc tatgagaccg aaggagaaat agaatttcat
    21301 gacattagac aagtcacaga ccaagacttt agacaactta gagggcaagt ggatatcatc
    21361 tgcggtggtt tttcccttgt caagcatttt cactcgcagg cagacgactg ggatttgagg
    21421 gcactaggag aactctcttc tttgagatta ctcgagcgac caaacagata aaaatcatac
    21481 ccataatcac atccaatcaa cgccattgac cgtaattcag ataaaaaatt gatatggaat
    21541 tatgccttgg aacgaaacct ccgtatgatt ttagaccgta tttcaaaaat gactggagca
    21601 aaaattatcg agaagcgtta ttcctaccgt gactatcaaa aatataggca gtctagtcat
    21661 aaatttgaat tgaaacaacg tctttatttt ttgatgcagc agtcaaagtt ctttgatgat
    21721 tttttagaaa aagcagagta attacatgtt catattgatt ttagtcagaa gcatagcaga
    21781 ttcatgatga cggatcgagt aatgaaaaaa ccaattcgag gccgtcaact cagtaaacga
    21841 gatttatatg atgaagaatt ttttcgtaca cattttgcca agatagaaat tgaaagtcga
    21901 ttagaatttt tgttgaaccg tgccaattca ttagaggagc tactattaaa agcaaaagaa
    21961 gtgaatctaa ccattgactt aaaacaaaaa atgtaacttt tatcctagaa gaagatactc
    22021 aaaagataag tttaggtcat aaaaaaataa gcgataagaa attatatgat gtcaattttt
    22081 tcaagattac tttaaaaata aggaagtcgg tgtttcagat cgattagaaa gtctacagaa
    22141 acagtacatg cttttcaaga agaacgagat aaagaggagg tatccactga agagagtaag
    22201 gaagtcttca agaaatacaa ggggcaacga gatgccatcc atgagtttga agttgaactt
    22261 gtggaacatc aaattgagag gttaattgct gaggacattt atattaaggt gtcttttggt
    22321 gtaaagcaga gtggtcttat tttcattcct aactatcaat tggatattag gaaagaagaa
    22381 aatcataaaa aatataaagt ctatattcgt gagaccgcac aattcttcat ttacaacaag
    22441 gaggcgtcta aacttaatcg ctatatgcga gggcgtgagc tcatttacca gttaaccaat
    22501 gatagcaaga gtattccaaa aagaagacga ccaaaaccat tgatacactt aagaaaaaga
    22561 ttgaagaaat aagtctcctc attgagttag atacggagaa taagccttat caagatatta
    22621 aagatgacat tgttaaagat atggctcaat tagatttgac cattacagag ttgcaggacc
    22681 atattgctca tctcaataag gttgcggagg tcttgcttaa tatgaacaac aacgatatag
    22741 agaaccgccg tttggccaga tatgactatg ccaagatgaa cttgactgca gctataaaaa
    22801 tagaagaagt tgagaaagag attgaaactt ctcaaaatga acttaatata tccatagatg
    22861 agtatgaata tctagtaaga aggttggaaa agtttggaga gatcttgagt tatagcaaaa
    22921 ttatcgatac ttctcgaaat gaaatacaat gggagtaatt atgatataat ttgggtggta
    22981 gcaattttta tatcagatat taaaatct
//
LOCUS       DATWEK010000028        22921 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.028, whole genome shotgun sequence.
ACCESSION   DATWEK010000028 DATWEK010000000
VERSION     DATWEK010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22921
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.028"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            139..933
                     /locus_tag="VCR92_001320"
     CDS             139..933
                     /locus_tag="VCR92_001320"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEP4268383.1"
                     /translation="MENMFSLQGKIALITGASYGIGFEIAKAYAQAGATIVFNDIKQE
                     LVDKGVAAYRELGIEAHGYVCDVTDEAGIQQMVSQIEDEVGVIDILVNNAGIIRRTPM
                     LEMAAEDFRQVIDIDLNAPFIVSKAVLPSMIAKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTTEDLAGPAVFLASDASNFVNGHILYVDGGILAYIGKQP"
     gene            958..1599
                     /locus_tag="VCR92_001321"
     CDS             958..1599
                     /locus_tag="VCR92_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEP4268384.1"
                     /translation="MKIALINENSQAAKNGIIYDALTSVTDKHGYQVFNYGMYGTEGE
                     SQLTYVQNGLLASILLTTKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     SQINGGNALSIPFAKGFGWGAELNLTLIFERLFAEPMGGGYPKERAIPEQRNARILSD
                     LKKITYRDLLAIVKDIDQDFLKETISGAHFKEYFFANAEPSELVAYLKSVLEQ"
     gene            1628..2629
                     /locus_tag="VCR92_001322"
     CDS             1628..2629
                     /locus_tag="VCR92_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEP4268385.1"
                     /translation="MSKLLLVGEPLIRVSPNQFQPLTNACDAQLFFGGSEANIARTLG
                     GFGLEARLFTALPDNPVGHAFHQFLKQSGVDMSLTAWQGHRVGLYYLENGFGCRASQV
                     YYDRCGSSFSALDKDSLDLAAIFEGISHFHFSGISLALGKKTQDLIEILAREARKRQV
                     CVSFDLNFRSSMIAVADAKRLFSHFAQYADIIFGMEPLLLDSDDFDMFDRNKADTTMI
                     RERLAGLYQRYQLQAIYHTERSNDAQGSNRFKAYAYDGQFYESCEVTTPVLQRVGSGD
                     AFVAGLLYQLLEGNEKQRNLDFAVATASLKCTVAEDQLYHSVQQVEAVLHNQRDVQR"
     gene            2634..3269
                     /locus_tag="VCR92_001323"
     CDS             2634..3269
                     /locus_tag="VCR92_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEP4268386.1"
                     /translation="MGKIEILTKLKANRLVLVVRGESSEEALACSLASIEGGIKTIEV
                     TYTNPFASEVIGQLAERFKEDPEVLIGAGTVLDDVTARQAILAGAQFIVGPNFNRAVA
                     LICHGYSIPYLPGCMTVNEVVTALESGVDMVKIFPGSTVGISFIRAIKSPLPQVEVMV
                     TGGVSSDNLKDWLAAGVDVLGIGGEFNQLASQKQYNLITKKAAHYIKSLRQ"
     gene            3565..4215
                     /locus_tag="VCR92_001324"
     CDS             3565..4215
                     /locus_tag="VCR92_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEP4268387.1"
                     /translation="MIKGIIFDMDGVLFDTEPFYLRRREDFFKTKGIPIDHLNSKDFI
                     GGNLQELWKELLGKNRDDAIVKAITTDYDAYKQAHKPPYQKLLITEVNSCLEQLKKQG
                     IKLAVASNSKRQDVLLALETTQIKDYFEIILAREDVSRGKPYPDIYNKAVQKLGLQKK
                     QLLVVEDSEKGIAAAKAANLTVFAITDYRYGIDQSQADHKIDHLGQLCVKIGCFGS"
     gene            4911..6035
                     /gene="queG"
                     /locus_tag="VCR92_001325"
     CDS             4911..6035
                     /gene="queG"
                     /locus_tag="VCR92_001325"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HEP4268388.1"
                     /translation="MTIKAEIKALAKEIGISKIGFTTADNFDYLEKSLRASVEEGRNS
                     GFEHKVMEDRIYPERLLESAKTIISIGVAYPHKLPQQPQKTPYKRGKITPSSWGLDYH
                     YVVGEKLDRLSKGIEELCRDFPLQQKAMVDTGALVDTAVAQRAGIGFIGKNGLVISKE
                     YGSYMFLGELITNLEIEPDKPVDYDCGDCRRCLDACPTSCLIGDGSMNAKRCLSFQTQ
                     DKGMMDIEFRKKIKTVIYGCDICQICCPYNKGINNSPATEIDPELAQPELIPFLSLSN
                     GQFKEKFGMIAGGWRGKNILQRNAIIALANAHDKTAVVKLIEIIDKNNNPIHTATAIW
                     ALGEIVKKPNDEMLAFMSHLTLKDEDSQKELELIRRKWQV"
     gene            6104..7202
                     /gene="prfB"
                     /locus_tag="VCR92_001326"
     CDS             join(6104..6175,6177..7202)
                     /gene="prfB"
                     /locus_tag="VCR92_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889043.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEP4268389.1"
                     /translation="MEVAEIRQKIVENKEKLTSFRRSLDLDRLEEEIALLENHMTEPD
                     FWNDNIAAQKTSQELNELKGKYDTFHNMQELSDETELLLEMLDEDDSLKEELEENLMQ
                     LDKIMGAYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDLLLRMYTRFGNANGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFASVE
                     VMPELDDTIEVEVRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVSSTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAQEVDALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFELAQVDKVMDGEINGFIDAYLKWRIED"
     gene            7221..7913
                     /gene="ftsE"
                     /locus_tag="VCR92_001327"
     CDS             7221..7913
                     /gene="ftsE"
                     /locus_tag="VCR92_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEP4268390.1"
                     /translation="MALIEMSGVTKKYRRSTTALRDVNVSVNQGEFVYLVGPSGAGKS
                     TFIKLLYREEQLTTGKLYVGEFNLTKLKARDVPILRRHIGVVFQDYKLLPRKTVFENV
                     AYAMEVIGEKRRHIKKRVPEVLDLVGLKHKMRSFPSQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMQLLERINVQGTTILMATHNSHIVNTFRHRVVAIEDGRIV
                     RDEEKGDYGYDD"
     gene            7906..8835
                     /locus_tag="VCR92_001328"
     CDS             7906..8835
                     /locus_tag="VCR92_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4268391.1"
                     /translation="MIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATL
                     LNIQRVASGVENNVHINTYLQVDSTDAAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVK
                     KITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEG
                     VEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIM
                     RLVGAKNSYIRGPFFFEGAWVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPL
                     DPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF"
     gene            complement(9145..9843)
                     /locus_tag="VCR92_001329"
     CDS             complement(9145..9843)
                     /locus_tag="VCR92_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEP4268392.1"
                     /translation="MPFIFRHSFFNKALIFWYTILMKIYKTINHIAGENTYYLVNDQA
                     VILIDPGSNGQEIIAKIKSFEKPLVAILLTHTHYDHIFSLDLVRDAFDHPPVYVSEKE
                     AAWLSSPDDNLSGLGRHDDIITVIARPAENFFKLKQPYQLNGFEFTVLPTPGHSWGGV
                     SFVFHSDELVVTGDALFRETIGRTDLPTSNFEDLITGIRQELFTLPNHYRVYPGHGPS
                     TTICHEKNANPFFH"
     gene            10011..10775
                     /locus_tag="VCR92_001330"
     CDS             10011..10775
                     /locus_tag="VCR92_001330"
                     /EC_number="1.1.1.304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-acetoin forming diacetyl reductase"
                     /protein_id="HEP4268393.1"
                     /translation="MSKVAIVTGAGQGIGFAIAKRLHADGFKIGILDYNEETAQAAVD
                     KLSPEDTVAVVADVSKRDQVFDAFQKVVDTFGDLNVVVNNAGVAPTTPLDTITEEQFE
                     KAFAINVGGTIWGSQAAQKHFRELGHGGKIINATSQAGCEGNPNLTVYGGTKFAVRGI
                     TQTLAKDLASEGITVNAYAPGIVKTPMMFDIAHEVGKNAGKDDEWGMEQFAKDITLKR
                     LSEPEDVANAVGFLVGDDSNYITGQTIVVDGGMVFH"
     gene            10883..13384
                     /locus_tag="VCR92_001331"
     CDS             10883..13384
                     /locus_tag="VCR92_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEP4268394.1"
                     /translation="MFCFIDIACYNRLTMTQKKLRKYAVVDLEATGAGPNASIIQVGI
                     VIIQGNKIIDSYETDVNPHESLDEHIVHLTGITDKQLAKAPDFGQVAHHIYQLIEDCI
                     FVAHNVKFDANLLAEALFLEGYELTIPRVDTVELAQLFFPRFEKYNLSHLSRQLNIDL
                     AEAHTAIADARATAILFLRLLQKIESLPIECLESLLAYSDSLLFETAMVIQEGLAKAK
                     PYDPNKYIKIRQILLPKGSKALKPYQISKSFPINMALLGLEERPKQTQFAQLIDEDYH
                     QGVASFIEAQTGIGKTYGYLLPLLAKEDQNQIIVSVPTKLLQDQLMAGEVAAIQEQFH
                     IACHSLKGPANYLKLDSFADSLDQNDQNRLVNRYKMQLLVWLLETKTGDLDEIKQKQR
                     FAAYFEQLKHDGDIKQSSEFYDYDFWRVSYEKAKTARLLITNHAYFLHRVQDDKDFTR
                     NKVLVFDEAQKLMLQLDQLSRHQLNLTVFLQTIQAKLSNPLPLLEKRLLESLSFELGQ
                     VSSDYYQNKEHQLAHDWSRIAGYAKELTGADYQELQAFFATSDGDYWLSSEKQEEKRV
                     TYLNSASKAFIHFQQLLPETVKTYFVSATLTISSEVTLADLLGFEEYLYHVIEKDKKQ
                     DQLVLVDQEAPIVTEVSDQIYVEAIAKRIESLKQEGYPILVLFNSKKHLLLVSDYLDQ
                     WQVPHLAQEKNGTAYNIKKRFDQGEQTILLGLGSFWEGVDFIQADRMITLIARLPFDN
                     PEDFFVKKMSHYLLEKGKNPFRDYFLPMTILRLKQAIGRTMRRQDQKSVVIILDRRLL
                     TKSYGQVILEGLGQEFLISQQNFHDCLVETDCFLI"
     gene            13719..14912
                     /locus_tag="VCR92_001332"
     CDS             13719..14912
                     /locus_tag="VCR92_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEP4268395.1"
                     /translation="MPKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFF
                     TPKHIQDKAIESIQNGTASFYTNASGLPELKAAIATYLKNQYGYHLSPDQIVAGTGAK
                     FILYAFFMAVLNPGDQVLIPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLER
                     ARTSKTKVVLINSPSNPTGMIYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFV
                     PISTLSEAIRRQTITVNGVAKSYAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVS
                     QYAAIEAFCGSQSSLEEMRLAFEERLNITYPLLCQVPGFEVVKPQGAFYFFPNVKKAM
                     EMTGFSDVTSFANAILEEVGLAVVSGAGFGAPENVRLSYATDIETLKEAVRRLHVFME
                     SNEIN"
     gene            14942..16288
                     /gene="asnS"
                     /locus_tag="VCR92_001333"
     CDS             14942..16288
                     /gene="asnS"
                     /locus_tag="VCR92_001333"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEP4268396.1"
                     /translation="MSKKLISIVDVKDYVGQEVTIGAWVANKSGKGKIAFVQLRDGSA
                     FFQGVAFKPNFIEKYGEESGLEKFDVIKRLNQETSVYVTGIVKEDERSKFGYELDITD
                     LEIIGESHEYPITPKEHGTDFLMDNRHLWLRSRKQMAVMQIRNAIIYATYEFFDQNGF
                     IKFDSPILSENAAEDSTELFETDYFGKPAFLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSFLSHEESLDLQEAYVKALIQGVLDRAPQALDILERDVE
                     ALKRYITEPFKRVSYDDAITLLQEHEADEDTDYEHLEHGDDFGSPHETWISNYFGVPT
                     FVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDNYDALVAKMDEL
                     GMDKSEYDFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIRP"
     gene            16703..17593
                     /gene="rapZ"
                     /locus_tag="VCR92_001334"
     CDS             16703..17593
                     /gene="rapZ"
                     /locus_tag="VCR92_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002282100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEP4268397.1"
                     /translation="MSDKHINLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPK
                     FLELIEQTNENRRVALVVDMRSRLFFKEINSTLDSIESNPSIDFRILFLDATDGELVS
                     RYKETRRSHPLAADGRVLDGIRLERELLSPLKSMSQHVVDTTKLTPRQLRKTISDQFS
                     EGSNQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYKVELREKTGLDEDVFNYVM
                     SHPESEVFYKHLLNLIVPILPAYQKEGKSVLTVAIGCTGGQHRSVAFAHCLAESLATD
                     WSVNESHRDQNRRKETVNRS"
     gene            17590..18567
                     /locus_tag="VCR92_001335"
     CDS             17590..18567
                     /locus_tag="VCR92_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEP4268398.1"
                     /translation="MKNPKMTVIGGGTGISIILKSLRNEAVDITAVVTVADDGGSSGE
                     LRNAMQLTPPGDLRNVLLAMSDMPKFYERVFQYRFNESDGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIYPSSEQALTLHAVFKDGHEVAGESSIAKYQGMIDHVY
                     VTNTYNDQKPQASRKVVEAILESDMIVLGPGSLFTSILPNLVIPEIKEALRQTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVAKVPQAYMNSNKFDEYLV
                     QVDHDFAGLCRAAKRVISSYFLRLENGGAFHDGNLVVEELMNLVRIVKQ"
     gene            18564..19475
                     /gene="whiA"
                     /locus_tag="VCR92_001336"
     CDS             18564..19475
                     /gene="whiA"
                     /locus_tag="VCR92_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEP4268399.1"
                     /translation="MSFTTKVKEELIHLSTGDNNELAAIIKLSGSLGLAHQSLHLSIT
                     TENAKIARYIYSLIEDAYVIVPEIRYHQKTNLRKNRVYTVYVEQGVETILADLKLADS
                     FFGLETGIEPQVLSDDNAGRSYLKGAFLAAGSIRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMQKFMLDAKTIEHKSGAVTYVQKAEDIMDFLIIIGAMSCKEDFEAIKLLREARNDIN
                     RANNAETANIAKTISASMKTINNIIKIMDTIGLESLPIELQQVAQLRVKHPDYSIQQV
                     ADALEFPITKSGVNHRLRKINKIADDL"
     gene            complement(19654..21072)
                     /locus_tag="VCR92_001337"
     CDS             complement(19654..21072)
                     /locus_tag="VCR92_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEP4268400.1"
                     /translation="MQTKRKVAIYSRVSTLHQAEEGYSIGQQIEALTKYCQAMGWVIY
                     DNYSDGGFSGGKLERPAMQKMIQDAKSGKFDTVVVYKLDRLSRNVRDTLYLVKDVFNA
                     NNVDFVSLQENIDTKSAMGNLFITLLSAIAEFEREQIKERMQLGVKGRAKSGKTTSWT
                     TPPFGYKYDTNTQSMTVDHYQAEIVRDMFNKIISGWSIMGITTYMRENYDGKWTHVKV
                     KRILENITYIGKVKYRNEIFDGEHAPILTEEIFYKAQKALEERTSKKDNTRPFQGLYM
                     LSNIAKCGYCGTPLKIDSYKPRKDGTRKRTYTCINRNPKRIKTAIYNDGEQCKESGRY
                     DVKDVERYVLNEISKLQLNPKSIESLYRDKPEENITAHQERLKKLETKLSKLNDLYIN
                     ELISMEALKQKSAELLKEKSSLETFINNNKRKINNKPAFEKVAKMDDVFKMSYDDQKK
                     IVKTLIKRVEVKRDEINVIFKL"
     gene            complement(21208..21615)
                     /locus_tag="VCR92_001338"
     CDS             complement(21208..21615)
                     /locus_tag="VCR92_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HEP4268401.1"
                     /translation="MKKKTAIIIATAFLFVASPAIETTVFPQAHTAYAVSKEYKNALE
                     TAELMKDANMSKKAFYQALQDESGFEKKAVDYAVKKLKISWKKNALASAKNFQDYGMS
                     KEKIKETLLSEEDGGGFTKSEANYAIKHLEDED"
     gene            complement(21666..22406)
                     /locus_tag="VCR92_001339"
     CDS             complement(21666..22406)
                     /locus_tag="VCR92_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268402.1"
                     /translation="MGLLSLLFGKKRTNIQPKTSMTFSSSDEFDYYTPEYFKILDTRP
                     NIFEIYGRPHNFPKYDDSFITNENYKLRELLLLVWWGNPKNGRKSTVTIPKYFFYSYN
                     LNAEKLTNDFKSNGLLVDIEEKTLLTEKGQTVYDKYKALWEIHVVKQYPTNLDIDFPS
                     WDKEQFELKLYQMELTYYKAHANHCKKLVDFFNSLNIPSTSTATAQDVHDQINYYINE
                     GNSDLAKVNDYQEKIAILKEKAAHRLSD"
     gene            complement(22410..>22921)
                     /locus_tag="VCR92_001340"
     CDS             complement(22410..>22921)
                     /locus_tag="VCR92_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4268403.1"
                     /translation="SIYEKLNENRQKKVLNFASDQLAEQEQENTVSSIFSKKEDDDKY
                     ITDYVQGLVAAGHGVFQCDNLYMEVKLRADDVPEEYDTIAKVAGDSMEPLIQDNDLLF
                     IKVTSQIEPNEIGIFQVNNKNFVKKLKCDYDGRWYLQSLNDKYEEIYLSENDDIRTIG
                     EVVDIYRED"
BASE COUNT         6919 a         3941 c         4775 g         7286 t
ORIGIN      
        1 aacaagaatg acagtttgga taagagcact cttttaaatt ttgaaccgtt ttcattaaaa
       61 tgattgacaa aactagttta ctttgttata gtcttggtaa acaggtttac ttaatctaat
      121 aacaaaaagg agaatcctat ggaaaatatg ttttcgttac aaggtaagat tgccttgatt
      181 accggagcat cttacggtat tggttttgaa attgccaaag cctatgctca agcgggtgca
      241 actattgtgt ttaatgacat caaacaagag ttagttgata agggggtggc tgcctatcga
      301 gagttaggga tagaagcgca tggctatgtt tgtgacgtga ctgatgaagc tggtatccaa
      361 cagatggtta gtcaaattga agatgaagta ggtgttattg atattctggt caacaatgca
      421 ggtattatta ggcgtacgcc gatgcttgaa atggccgcag aagattttcg tcaagttatt
      481 gatattgatt taaatgctcc ttttattgtg tcaaaagctg tattaccatc aatgattgca
      541 aagggacatg gtaaaattat aaatatctgt tctatgatga gcgaattggg gcgtgaaaca
      601 gttagtgcct acgcggcggc taaaggtggc ttgaaaatgt taaccaaaaa tatagcctct
      661 gagtttggag aagccaacat tcaatgtaat gggattggtc ctggctacat tgcgacgccc
      721 caaacagctc cgttgagaga gcgacaagca gatggtagtc gtcatccttt tgatcaattt
      781 atcattgcta aaacaccagc agcacgttgg gggacaacag aagacttagc tggtccagct
      841 gtttttctag ctagcgatgc cagtaatttt gtcaacggcc atattcttta tgtcgacggt
      901 ggcattttag cttatattgg aaaacaacct taatcacaca ctagaaagag attttatatg
      961 aaaattgcat taattaatga aaatagccaa gcggctaaaa atggtattat ttacgatgcc
     1021 cttacctcag tgacagataa acacggctac caagtcttta actatggcat gtatggcaca
     1081 gaaggtgaaa gccagttgac ctatgttcaa aatggactct tagcttctat tttattgacc
     1141 actaaggcgg ccgattttgt ggtgactggt tgtgggacag gtgtgggagc tatgttggcc
     1201 ttgaacagct tcccaggggt tacctgtggt tttgcgagtg agccaacaga agcatatctc
     1261 ttttctcaaa tcaatggtgg taatgccttg tccattcctt ttgccaaagg ttttggttgg
     1321 ggagcagagt tgaatttgac cttaatattt gaacgcctct ttgcagaacc aatgggtggc
     1381 ggttacccta aagagcgagc tattcctgaa cagcggaatg cacgtatttt aagtgatctg
     1441 aaaaaaatta cttacagaga tttgttggca attgtcaaag acatcgacca agatttcctc
     1501 aaagaaacga tttctggcgc tcattttaaa gagtacttct ttgccaatgc ggagccgtca
     1561 gaattagtcg cttatttgaa atcagtactt gaacagtaat tccattttga cgaggaaagg
     1621 aggtcacatg tctaagttat tattggttgg tgaaccgctg attcgcgtta gccccaatca
     1681 gtttcagcct ttgaccaatg cctgcgacgc tcagcttttt ttcggcggtt cagaagctaa
     1741 tattgcaaga actctaggcg gttttggctt agaagcaagg ctatttacgg ccctaccaga
     1801 taatcctgtt ggtcacgctt ttcatcagtt tttgaagcaa agcggtgtgg acatgtcctt
     1861 gacggcttgg caaggtcatc gcgttgggct atattacctt gaaaatggct ttggctgtcg
     1921 ggctagtcag gtttattatg accgctgtgg ctctagcttt tcggccttag ataaggatag
     1981 tcttgattta gctgccattt ttgaaggcat tagtcacttt cattttagtg ggatcagttt
     2041 ggcgctgggc aaaaaaactc aggatctgat tgagatacta gcgagagaag ctaggaaaag
     2101 gcaagtttgt gtttcttttg atcttaactt tagatctagt atgattgcgg tagctgatgc
     2161 taaacgactc ttttctcact ttgctcaata cgcggatatt atttttggca tggaaccttt
     2221 gctgttagat agtgacgatt ttgacatgtt tgataggaat aaggcagata ctacgatgat
     2281 tagagaacgt ctggcaggac tttatcagcg ctatcagtta caagctattt accatacgga
     2341 gcgttcaaat gatgcccaag gcagtaatcg tttcaaggct tatgcctatg atgggcagtt
     2401 ttacgaatcc tgtgaagtga cgaccccagt cttgcaacgg gttggaagtg gagatgcttt
     2461 tgtggcgggt ttactttatc agttgttaga aggtaacgaa aagcagcgca accttgattt
     2521 tgctgtggca acagctagcc taaaatgtac agtagctgaa gatcagctct atcacagcgt
     2581 ccaacaagta gaagcagtct tacataatca acgggatgtc cagaggtgat gatatgggaa
     2641 aaatagaaat cttaaccaaa cttaaggcta atcggcttgt cctggttgta cgaggagagt
     2701 ctagtgagga agctttagct tgcagcctgg ccagtattga aggtggcatt aagacaattg
     2761 aagtcaccta tactaacccc tttgctagtg aggttatcgg tcaattagct gaacgcttca
     2821 aagaagatcc tgaggtattg ataggtgctg ggacagtttt ggatgatgtc actgcccgcc
     2881 aagctatttt agcaggagca cagtttattg ttggtcctaa tttcaatcga gcagtggctt
     2941 tgatttgtca tggttatagc ataccttatt taccaggttg tatgacggtt aatgaagtgg
     3001 ttacagcatt agaatcaggg gttgatatgg tcaaaatttt tcctggttct actgtaggga
     3061 tatcctttat tcgggcaatc aaatctcctt tgccacaagt agaggttatg gttacaggcg
     3121 gagtttcttc agataatctc aaagactggc tagctgctgg agtagatgtt ctaggcatag
     3181 gaggcgagtt taatcagtta gcgagccaaa aacaatataa cctaatcact aagaaagccg
     3241 ctcattatat caaaagtttg cgacaataat ctaaaaaacg tttttacctt ggctttagtg
     3301 ctagtaaaaa cgttttttta tcattcattc aattaatatg cttctgctca tgtttttcca
     3361 gatagtatag atataagagc agctaattta acaagatgag cctgttgttt gatatatagg
     3421 atataaactt tttatgatca aacaaaagta ataccttttg aattcgttag tattgatctg
     3481 atctaaagtg acatcactta gaatggacta gctgtacagc ttttacagca acttatgcta
     3541 aaatagaaaa aaggagaaat gttgatgatt aaaggaatta tttttgatat ggacggtgtt
     3601 ttatttgata cagaaccttt ttatctgagg cgacgagaag atttttttaa gacaaaggga
     3661 attcccattg atcatttgaa ctctaaagat tttattgggg gcaatcttca agaattatgg
     3721 aaagagttgt taggtaaaaa tagggatgat gctatcgtta aggcaattac aactgactat
     3781 gacgcttaca aacaagcgca taagcctcct tatcaaaaac tgttgattac agaagtgaac
     3841 tcttgtcttg aacagttgaa aaaacaaggt attaaactgg ctgtggcatc aaactcgaag
     3901 cgtcaggatg ttttgttggc gttggagaca acgcaaataa aagattattt tgaaataatc
     3961 ctagcgcgtg aagatgtttc tagaggcaaa ccttatccag atatctataa taaagcagta
     4021 caaaaactag gattacaaaa aaaacaactg cttgtagtag aagacagcga aaaaggcatt
     4081 gctgccgcca aagcggccaa tctgacagtt tttgccatta ccgactaccg atatggcatt
     4141 gatcagagtc aagctgatca caagatagat catttaggac aactgtgtgt aaaaatcggt
     4201 tgttttggat cgtgaagtaa cgcaactaac tgatcattga tgatacttca agacacttaa
     4261 gaatacgtct aggactttct acagaccaat aacaagaata cgtttatgtg tttttactgt
     4321 tttttagcta cctatttaca atatgacact gaaaagagta ctatgtttaa gttattatca
     4381 aaaaaaccgt cgcataagat cacctagaaa aggattatga tttttgtgat ttggatgcga
     4441 tcattagtcg ttgaccatct ttatgtggca ggagatatgt ttaaccgtgg tcattatttg
     4501 gatttgtttt tagattggct agtgagtaaa tatagaagga tcataatact gctttgacaa
     4561 aggcagtatc tgagtccatg agttgcacgg gtaatgtgac tcggttttgg ttaggtataa
     4621 taatatttgg aagtgttatg ctgcttgtct tcgtaggtcc attgcttata gtcagactta
     4681 ctttagagct gagctgactg tctagacaag acgtgatgga gatgtgattt ctgaccaagt
     4741 agaggtaacc agaaaaggga cttttacgat gtaattgaat ttacttgttg cattcttgtg
     4801 catgttaaga gagaaaaccc agataaatca ggaagtaaaa tggttatgtt tgattagaat
     4861 tgtccttctt tttccttgaa gtcttaactt attttgatta tgatagtagt atgactatta
     4921 aggcagaaat taaggcactc gccaaagaaa ttggtatctc taaaattggt tttacgacgg
     4981 cagataactt tgattatttg gaaaagtcat tgcgtgcttc tgtggaagag gggcgcaatt
     5041 caggatttga acataaagtc atggaggatc gtatctaccc tgaaaggctt ttagaatcgg
     5101 ctaaaacgat tatttcaatt ggcgttgctt atcctcacaa acttcctcag caacctcaaa
     5161 aaacacctta taaacgtgga aaaattacac ctagttcgtg ggggcttgat tatcattatg
     5221 tggtcggcga aaagttagac agactatcaa aaggcattga agagctgtgt cgagattttc
     5281 ctttgcaaca aaaagcaatg gtcgatactg gagctttagt tgatactgca gttgcccaaa
     5341 gagcgggtat tggttttata ggaaaaaatg gtttagttat ttctaaagaa tatggctctt
     5401 atatgttttt gggagaatta attaccaatt tagagatcga gccagacaag cctgtcgatt
     5461 atgattgtgg tgactgtcgt cgttgtctag atgcctgtcc aacttcttgt ttaattggtg
     5521 atggctcaat gaatgccaag cgttgtctat catttcaaac ccaagataag ggaatgatgg
     5581 acatagagtt tcgaaaaaag attaaaacag ttatctatgg ttgtgatatt tgccaaattt
     5641 gctgtcctta taacaagggt ataaacaatt caccagctac agagattgat cctgagttgg
     5701 ctcaaccaga attaatacca tttttgagtt tatcaaatgg acaatttaaa gaaaaatttg
     5761 gtatgattgc tggaggttgg cgaggtaaaa atattttaca gcgtaatgcc attattgcgc
     5821 tagcaaatgc tcatgataaa accgcagtgg tcaaattaat agagattatt gataaaaata
     5881 ataaccctat tcatactgca acagctatat gggcattggg agaaattgtc aaaaaaccaa
     5941 acgatgagat gctggcgttt atgagtcatt taaccttaaa agatgaagat agccaaaaag
     6001 agttggaatt aatccgtcgt aaatggcaag tttaagcctt ttatggtatt tttaagaacc
     6061 ttatgataaa ataaaacaga ttaacaaaga ttggagaaat ctcatggaag tggctgaaat
     6121 tcgccaaaaa atagtagaaa ataaagagaa gttgactagc ttcaggaggt ctctttgact
     6181 tagatcgttt ggaagaggag attgctcttc ttgaaaatca catgactgag ccagactttt
     6241 ggaatgacaa tattgcagcg caaaagacat ctcaagaact aaatgagtta aaaggtaagt
     6301 atgatacttt ccataatatg caagaattat ctgacgaaac agaactctta cttgagatgc
     6361 ttgacgaaga tgattctttg aaagaagaat tagaagaaaa tctaatgcag ctagataaga
     6421 taatgggtgc ttatgaaatg acgcttctct tatctgaacc ctatgaccac aataatgcta
     6481 tcttagaaat ccatcctggt tcaggaggaa ctgaagcgca agattgggga gatttactct
     6541 tacgaatgta tacccgtttt ggcaatgcta atggtttcaa agtagaagta ttggattatc
     6601 aagcaggaga tgaagctggt attaaatcgg ttaccctctc ttttgaaggc cccaatgctt
     6661 atggtttgtt gaaatcagaa atgggagttc atcgcctcgt tcgtatatca ccttttgatt
     6721 cagctaaacg tcgtcatact tcatttgctt cagttgaagt gatgccagag ttagatgata
     6781 cgattgaagt agaagtacgt gatgatgaca ttaaaatgga tactttccgt tccggaggag
     6841 ctggtggtca gaacgtcaat aaagtatcaa caggtgttcg tttgacgcat attccaactg
     6901 gaattgtggt atcgtctacc gttgaccgta ctcaatatgg gaaccgcgat cgcgctatga
     6961 agatgttgca ggctaagcta tatcagttag aacaagaaaa gaaagcacaa gaagtagatg
     7021 ctctcaaggg tgataaaaaa gaaatcactt ggggaagtca gattcgttct tatgttttca
     7081 ccccttatac gatggtgaag gatcatcgta ctaactttga gcttgctcag gtagataagg
     7141 ttatggatgg agaaatcaat ggctttattg atgcctacct taagtggcgc attgaagact
     7201 aaaaataata aaggagaaac atggcactaa tagaaatgtc tggtgttact aaaaaatacc
     7261 gccgctcaac gaccgccctc agagacgtca atgtttctgt taatcaaggt gagtttgttt
     7321 atctcgtagg cccatcaggt gctggtaaat caacttttat caaactcctt taccgtgaag
     7381 aacaactgac aactggtaag ctatatgtgg gtgaattcaa tttaactaaa ctaaaagcac
     7441 gtgatgttcc gattcttcgt cgtcacatcg gagtagtttt tcaagattac aaactgctac
     7501 caagaaaaac agtctttgaa aatgtagctt acgccatgga agttattggt gaaaagcgcc
     7561 gccacattaa aaaacgcgtg ccagaggtac tcgatttagt tggcttgaaa cataagatgc
     7621 gttcttttcc aagtcagcta tcaggagggg agcagcaacg tgtggccatt gcgcgtgcga
     7681 ttgttaacaa ccctaaatta ttgattgcag atgaaccgac agggaattta gatcctgaga
     7741 tttcatggga aattatgcag ttacttgaac gtattaatgt tcagggaaca actatcttaa
     7801 tggcgacaca caacagtcat attgtgaata catttcgtca tcgtgttgtt gctattgaag
     7861 atggtcgcat agtacgtgat gaagaaaaag gagattatgg ttacgatgat tagatacttt
     7921 ttccgtcata tttgggaatc cattaaaaat cttaaacgca acttttggat gacatttgct
     7981 tcagttagta tggtggctgt tacattgact ttagttggtg tttttgcggc gacattgttg
     8041 aatatacagc gtgttgcttc gggtgttgaa aataatgtcc atatcaatac ctacttacaa
     8101 gttgattcaa ctgatgctgc aaaagttatt caaaatactg ccggtgaacc tgttaataac
     8161 gataactacc acagtgttta cgacaaaatt gctcagataa aaggtgtcaa aaagattaca
     8221 ttttctagca aggatgaaca attgaaaaaa ttgcaagaaa ccttaggtga tgtttggaat
     8281 atgtatgacc aagacactaa tccgctccaa gatatctatc ttattgagac ccagacgcct
     8341 aaacaagtta aggcgatcac taaaaagatc agaacgattg aaggcgtaga agccgcagat
     8401 tatggaggga ttaactccga taaactattt aagttttcaa cattaattca aacttggggg
     8461 ttgatcggaa cagcaatgct attatttgta gctgtctttc tcatttcaaa cactattcgt
     8521 atgactatta tgtctcgtaa acgcgacatt gaaattatgc ggttagttgg tgctaaaaat
     8581 tcttatattc gagggccttt cttttttgaa ggggcttggg ttggcttgtt aggagctgtt
     8641 ttaccatctc ttctgattta ttatggatat gatcttgttt ataagcattt tgcacaagaa
     8701 ttacaacgta ataatctctc gatgtatccg cttgatcctt atgtatatta cctgattggt
     8761 gctttgtttg tcataggtat tatgattggt tcgcttggtt cagtgctttc tatgagacgt
     8821 tatttaaaat tctaaaaaaa gcgctgctga cgaaacgtag cgaccctcaa aagttggacc
     8881 tcttatgtta ttccaaggac ttcgttttgt attgcacagg actggtcctt ttcattttgt
     8941 tttgattcat ttgtttattt gtaataggca atatagttta aaatagcagt ttctaaggtt
     9001 tcaagagaag aaaagcaccc caaaagttag atgtttgatg tatctaactt ttggggtgtc
     9061 attcaaaatt tagtggctct tttttagtaa aatactatga tttcagtttt aggataacct
     9121 caaacagtat ctaaaatagc tatgtcaatg aaaaaagggg ttagcatttt tttcgtgaca
     9181 aatggtagta gaaggaccat gcccaggata aactcggtaa tgattaggta aggtgaatag
     9241 ttcttggcga ataccagtaa tgaggtcctc aaagttactg gtaggtaagt cagtacgacc
     9301 gatagtttca cgaaatagag catcgccagt aacgactaat tcatctgagt ggaaaacaaa
     9361 tgagactcct ccccaagaat gaccaggtgt tggtaaaact gtgaattcaa aaccatttag
     9421 ttgatagggt tgctttaatt taaaaaagtt ctctgccggt cttgctataa cagtaatgat
     9481 atcatcatga cggcctaacc cagataaatt atcatctggg gaagatagcc aagcggcttc
     9541 tttttctgaa acataaacag gtggatgatc aaaagcatct ctgaccaaat ctaaactaaa
     9601 aatatgatca taatgagtat gcgttaagag gatagccact aaaggttttt caaaggattt
     9661 aattttagca atgatttctt ggccgttact tcctggatca atgaggataa cagcttgatc
     9721 attaacgagg taataagtat tttcaccagc aatgtggttt attgttttat agattttcat
     9781 aaggatagtg taccaaaaaa tcaaggcttt gttaaaaaaa gagtggcgga aaataaatgg
     9841 caattagttt cagaaaatat gagatctcac agcaatttct tgacaccgtt ttcataaagg
     9901 tgtatcataa aagtaatcaa taagccaagc ctaaagctga acttagttta agaacactga
     9961 ctttttgaga gcaacctaat cggttgacta aaaaatatga ggtggaagat atgtcaaaag
    10021 ttgctattgt tactggtgct ggtcaaggaa ttggatttgc tattgcgaaa cgtcttcatg
    10081 cagacggctt taaaataggc attttagact ataatgaaga gactgctcag gctgcggttg
    10141 ataaactatc acctgaggat actgttgcag ttgtagcaga tgtttcaaaa cgtgaccaag
    10201 tttttgatgc tttccaaaaa gttgtagata cttttggtga tttgaatgtt gttgttaaca
    10261 atgcaggtgt tgccccaaca acccctcttg acacgattac tgaagagcag tttgaaaagg
    10321 cttttgcaat caatgtcgga ggaacgattt ggggaagcca agcagctcaa aaacatttta
    10381 gagaattagg tcatggcgga aaaattataa atgcaacgtc acaagcagga tgtgaaggga
    10441 atcctaattt gactgtttac ggtggtacaa aatttgcagt tcgtggtatt acacagactt
    10501 tggcaaagga tttggcatca gaaggaatca cagtcaatgc ttacgcacca ggtattgtta
    10561 aaacacctat gatgtttgat attgcccatg aagttggtaa aaatgcaggc aaagatgatg
    10621 aatggggtat ggagcaattt gcaaaagata tcactttgaa acgcttgtct gaaccagaag
    10681 atgttgctaa tgcagtaggc ttcttagtgg gagatgattc aaattatatc actggacaaa
    10741 caatagttgt cgatggtggt atggtattcc attaaaaatg attaatactg acactgtgag
    10801 tttcactcac agtgtttttt atatttctta aaaaattatc ctatcttgat tattggagtg
    10861 atggcacctt tgaggtatag tcatgttttg ttttatagat atagcgtgct ataatagact
    10921 tactatgacc cagaaaaaac ttagaaaata tgcagtagtg gacttggagg ctactggagc
    10981 aggtcccaat gcttctatta ttcaggttgg gattgttatt atccaaggaa ataaaattat
    11041 tgatagttat gaaacagatg ttaatcctca tgaatctttg gatgagcata ttgttcattt
    11101 gacaggtatt acggataagc agttggctaa agctccggat tttggtcaag tggcgcatca
    11161 catttatcaa ttgattgaag attgtatttt tgttgcccac aatgtaaagt tcgatgcaaa
    11221 tttattggca gaagctcttt ttttggaagg atatgagtta acaataccac gtgttgatac
    11281 tgttgaatta gcccaactat ttttccctcg ctttgaaaag tataacctta gtcacctatc
    11341 taggcagctc aatattgatt tggcagaagc tcatactgct attgcagatg caagagctac
    11401 agctatactg tttttaagac ttttacaaaa aattgagagc cttccaattg agtgcttaga
    11461 aagcttatta gcctattcag atagcctgct atttgaaaca gcaatggtca ttcaagaagg
    11521 attagccaag gccaaacctt atgatcccaa caaatacatt aaaatcagac agattctctt
    11581 accaaagggc tcaaaagctc tcaagcctta tcaaatatca aaaagcttcc ctattaatat
    11641 ggcactatta ggtctggaag aaaggcctaa acagactcaa tttgctcagt taattgacga
    11701 agattaccat cagggagtag ctagttttat tgaagctcag acaggtattg gaaaaaccta
    11761 cggctacctg ctaccccttt tggcaaaaga agatcaaaac caaatcattg ttagtgtgcc
    11821 aaccaaactt cttcaagacc aattaatggc tggtgaagta gctgctattc aagaacaatt
    11881 tcacatcgcc tgccatagtt taaaagggcc tgccaattac ctaaagctag atagctttgc
    11941 agatagtttg gaccaaaatg accagaaccg tttggtgaat cgttataaaa tgcaattatt
    12001 ggtttggctc ttagaaacta agacaggaga ccttgacgaa atcaaacaaa agcagcgctt
    12061 tgccgcttat tttgagcagc ttaagcacga tggagacatt aagcagtctt ctgaatttta
    12121 cgattatgat ttttggagag ttagttatga aaaagccaaa acagcccgtc tcctgattac
    12181 caaccatgct tattttttac accgtgttca agatgacaag gactttacta gaaacaaggt
    12241 cttggtattt gatgaggccc aaaagctgat gctccaatta gatcaattat cacgtcatca
    12301 gcttaacctg acggtttttt tacaaacaat acaggccaag ttaagcaacc ctttacctct
    12361 tttagaaaaa cgcttattgg aaagcttgtc gtttgaactg ggacaagtgt caagtgatta
    12421 ctatcaaaat aaagagcacc agcttgctca tgattggtct cgtatagctg gctacgccaa
    12481 agaattaaca ggagcagatt atcaagagtt acaagccttt tttgctacct cagatggtga
    12541 ctactggctt agtagcgaaa agcaagagga gaagcgagtg acttatctaa acagtgctag
    12601 taaggcattt attcatttcc aacagctctt accagaaacg gtgaaaactt attttgtttc
    12661 tgccacttta accatcagct cagaagtaac cttggcagac ctattaggtt ttgaagagta
    12721 tctctatcat gtcattgaaa aggataaaaa gcaagaccag ttggtgcttg ttgatcaaga
    12781 ggcgcctatc gtgacagaag tcagtgacca aatctatgtg gaagcaattg caaaacgaat
    12841 cgaaagcttg aagcaagagg gttatcctat tttagtgctt tttaattcta aaaaacactt
    12901 gctgttggtt tcagactatc tagaccaatg gcaagtgcct cacttagcgc aggaaaagaa
    12961 tggaacagct tataatatta aaaaacggtt tgatcaagga gagcaaacta ttttgcttgg
    13021 tttaggttct ttttgggaag gagttgattt tattcaagcg gatcgtatga ttacccttat
    13081 cgcacgattg ccctttgata acccagagga tttctttgtt aagaaaatga gtcattatct
    13141 attggaaaaa ggtaaaaatc ctttcagaga ttacttcttg ccaatgacta ttttgcgatt
    13201 aaaacaggct attggtcgca cgatgcgtcg acaagatcaa aagtcagtgg ttattatttt
    13261 ggatcgtcgt ctccttacaa agtcctatgg acaagttatt ttggaaggtc tcggtcagga
    13321 atttttgatt tctcaacaaa attttcacga ttgtctagta gaaacggact gttttctgat
    13381 ataatggaaa ggatctatta tatcagaaaa atttttaatg gcgttaagca caatcaacta
    13441 acatttaaat tagtttgaac ttttattatg ctcttttaga caactgttca aatgttttcg
    13501 aattgttttt ttgataagga caataaatga acaaattttt ggttttagta aacccaatta
    13561 ctgttctttt cattaatgtc agttgctatc aaaacagctt gtcatagttc gtgcgatcag
    13621 tagcgagtat tggtaaaact gaaaccgtag attatgaaaa aatgatctgt tgatcattaa
    13681 ttaatctgaa gataagaagt cgataaaaag gagatacgat gcccaaacta tcaaagcgag
    13741 ttttagagat gaaagagagt gttactctgg ctgcaggtgc tagagctaag gctttgaaag
    13801 cgcagggtcg tgatgtactg aatttaactt taggagaacc agattttttt acacctaagc
    13861 acattcaaga caaggcgatt gaatctattc aaaatggtac ggctagcttt tatacaaatg
    13921 cttctgggct tccagaatta aaagctgcga ttgccacata cctgaaaaat cagtatgggt
    13981 atcacttgtc tcctgatcag attgtggcag gaacaggtgc caagttcatc ctttatgcct
    14041 tttttatggc tgttttaaat cctggtgacc aagttctcat tccaacacca tattgggtat
    14101 cttattctga ccaagtaaaa atggcagaag gtcagccgat cttcgttcaa ggactagaag
    14161 aaaatcaatt caaggtaact gttgaccagc tggaaagagc aaggacaagt aagactaaag
    14221 ttgtccttat caattctcct tccaatccaa caggcatgat ttatggtgct gaggaattaa
    14281 gggccattgg agaatgggcg gtgcacaacg atattcttat tctggcagat gatatttacg
    14341 ggtccttagt ctataacggc aatcagtttg ttcctatttc aacactctca gaagcgattc
    14401 gtcgtcaaac cattacggtc aatggcgtgg ctaaaagtta tgccatgaca ggctggcggg
    14461 ttggttttgc agcaggtgaa ccagagatca tttcggcaat gagtaagatc atcgggcaga
    14521 ctacctctaa cctgacaacc gtttcacaat atgctgctat cgaggctttc tgtggtagtc
    14581 agtcatcact tgaagagatg cgattagcat ttgaagagcg ccttaatatc acttatccat
    14641 tgttgtgtca ggtccctggg tttgaggttg ttaaaccaca aggagctttt tacttctttc
    14701 caaacgttaa gaaagccatg gaaatgacag gtttttccga tgtgacaagc tttgctaatg
    14761 ctattttaga ggaagtcgga ttagctgttg tgagtggagc aggctttggc gcaccggaaa
    14821 atgttcgtct gagttatgct acagatatcg aaacccttaa agaagctgtt cgtagactgc
    14881 atgtctttat ggaaagtaat gaaattaatt aaattaatta aataaaaata gagagaaact
    14941 tatgtcaaaa aaacttattt caattgttga tgttaaagat tatgttggtc aagaagttac
    15001 tattggtgct tgggttgcta acaaatcagg taaaggtaag attgcgtttg tacagttgcg
    15061 cgatggttcg gcttttttcc aaggtgtcgc ttttaaacca aacttcattg aaaaatatgg
    15121 tgaagaatca ggtcttgaaa aatttgacgt tattaaacgt ctcaaccaag aaacatctgt
    15181 ttatgtaaca gggattgtta aagaggatga gcgttctaaa tttggctatg agcttgatat
    15241 tactgacctt gaaatcattg gagagtcaca tgaatatcct ataactccta aagagcatgg
    15301 gacagacttc ttaatggaca accgtcatct ttggttgcgt tctcgtaaac aaatggctgt
    15361 tatgcaaatt cgtaacgcta ttatttatgc aacttatgaa ttctttgacc aaaatggttt
    15421 tatcaaattt gatagcccaa ttttatcaga aaatgcagca gaagattcaa cagagttatt
    15481 cgaaacagac tattttggga aaccagcatt tcttagccaa tctggtcaat tataccttga
    15541 agctggagca atggctctag gccgagtttt cgactttggt ccagtctttc gtgctgaaaa
    15601 atctaaaaca cgtcgccatt taacagaatt ttggatgatg gatgctgagt attctttctt
    15661 atcacatgag gaatcacttg accttcaaga agcttatgtt aaagcattga tccaaggcgt
    15721 tctagatcgt gcgcctcaag cacttgatat tttagaacgt gatgttgagg ctctcaaacg
    15781 ttatatcaca gaaccattca agcgtgtttc ttatgatgat gctattacac ttcttcaaga
    15841 gcatgaagca gatgaagata cagattatga acatttagag catggtgatg actttggttc
    15901 cccacatgaa acttggattt ctaattactt tggagtaccg acatttgtag tgaattaccc
    15961 agcaagcttt aaagcatttt atatgaaacc agttcctgga aatccagaac gcgttctttg
    16021 tgctgatctt ttagctccag aaggttatgg agagatcatt ggcggctcaa tgcgtgaaga
    16081 caactatgat gctcttgtgg ctaaaatgga tgaactaggt atggataaat cagaatatga
    16141 cttttacctt gaccttcgta aatatggctc tgttcctcat ggcggttttg gtataggtat
    16201 tgaacgtatg gtaacttttg ttgctggtac caaacatatt cgcgaagcta ttccattccc
    16261 acgtatgtta catcggatta gaccctaata atacaaaaaa gttcatgtca tctatgaact
    16321 ttttgtattg gtaagaggtg agtgtgttat aaaaaaatca atatgtccta aaggagagat
    16381 aagaaatagt agagtttgaa cctacatcct ttgtgaagat aaattttgga agtttagtag
    16441 atcagttagc agataagaca atatagcctt gctcaaggga tattttatag acaagtattt
    16501 ggactacgat tatcaaatag acagtctcat ttgatactaa aaaggtctcg tctattcata
    16561 taataggaga gttacgggag ttattattaa aattagctga tttttacagt tcaaaatgtg
    16621 ttaccacttt ttcacttctt agctttctta tgtatgtggt ataatgaagg tggacggttc
    16681 gatagagaaa gggaaattgt aaatgtcaga caaacacatt aatttagtta ttgtgacagg
    16741 aatgagcggc gctggaaaaa cagttgccat tcagtctttt gaggatctag gctactttac
    16801 cattgataat atgcccccag ccttggttcc aaaattttta gaattaattg aacaaaccaa
    16861 tgaaaatcgt agggtggctt tggttgtcga tatgagaagt cgtttgtttt tcaaggaaat
    16921 taattctacc ttagatagta ttgaaagcaa tcctagcatt gattttcgga ttcttttttt
    16981 ggatgcaacg gatggagaat tggtgtcacg ctataaagaa accagacgga gccacccttt
    17041 ggctgcggac ggtcgtgtgc ttgatggtat tcgattggaa agagaactcc tatctccttt
    17101 gaaaagcatg agccaacatg tggtggatac aacaaaattg acccctagac aattgcgtaa
    17161 aaccatttca gaccagtttt ctgaagggtc taatcaagcc tctttccgta ttgaagtgat
    17221 gagctttggg ttcaaatatg gtcttccttt ggatgcggat ttggtttttg atgtgcgttt
    17281 tctacccaat ccttattata aggtagagct tcgtgaaaaa acaggactag atgaggacgt
    17341 ttttaattat gtgatgtctc acccagaatc agaggtgttt tacaagcatt tgttaaacct
    17401 tattgtccct atcttaccgg cttaccaaaa agaagggaag tctgtcttga cggtggctat
    17461 tggctgcaca ggaggccaac accgcagcgt tgcctttgcc cattgcttgg cagaaagtct
    17521 ggcaacagat tggtcggtta atgaaagcca tcgtgatcaa aatcgtcgta aggaaacggt
    17581 gaatcgttca tgaaaaatcc taaaatgact gttataggtg ggggtactgg catctccatt
    17641 atcctaaaaa gccttcgtaa tgaagcagtt gatattactg ctgtggtcac tgttgcagat
    17701 gatggtggtt cctcaggaga acttcgtaat gccatgcaat taaccccgcc aggagactta
    17761 cggaatgtct tgttagcgat gagtgacatg ccaaaatttt atgagcgggt tttccaatac
    17821 cgttttaacg agagtgatgg agccttggct ggtcaccctc taggcaatct cattattgct
    17881 ggtatctctg aaatgcaagg ctcaacctac aatgccattc aaattttaac caaatttttc
    17941 catattacag gtaaaattta cccctctagc gagcaggcct tgacccttca tgctgttttt
    18001 aaagatgggc acgaagtagc aggagaaagt tctattgcca aatatcaagg catgattgac
    18061 catgtctatg tgaccaacac ctacaacgac caaaagcctc aggccagtcg taaggtggtt
    18121 gaggctattc tagaaagtga catgattgtc ttgggaccag gctcactgtt tacctctatt
    18181 ttacctaatt tggtcattcc agaaattaaa gaagctttgc gccagactaa agcagaagtg
    18241 gtgtatattt gtaatatcat gacccagtat ggtgaaacag aacaattttc agatgcagac
    18301 catgtggctg ttttaaatca gcacttagga agagatttga ttgatacggt tttggtaaat
    18361 gtggctaagg tgccgcaggc ttacatgaat tctaacaaat ttgatgaata cctcgttcag
    18421 gttgatcacg actttgctgg cctttgcagg gctgctaagc gtgtgatttc gtcttatttt
    18481 ttacggttgg agaatggcgg agcttttcac gatggtaact tagtggtgga agaattaatg
    18541 aatttagtga ggatagtcaa gcaatgagtt ttacaaccaa ggtcaaagag gaattaattc
    18601 acttgtccac aggtgacaac aatgaattgg ccgccattat caaattatca ggcagcttgg
    18661 gcttagctca ccaaagcctt catttatcca ttaccactga aaatgctaaa attgcccgct
    18721 acatttattc tcttattgaa gacgcctatg ttatcgtgcc agaaatcagg tatcatcaaa
    18781 agacgaacct gcgcaaaaac cgtgtttaca ccgtctatgt tgagcaaggt gtggaaacca
    18841 ttttagccga tttgaaatta gcggactcct tttttggtct ggaaacaggc atcgaacctc
    18901 aggttttatc agacgataat gctggccgtt cttatcttaa aggggctttt ctagcggcag
    18961 gtagcatcag agatcctgag tcaggcaagt atcagttaga aatctattca gtttatcttg
    19021 atcatgctca agatttagct caactcatgc aaaaatttat gctagatgcc aaaaccatcg
    19081 agcataaaag cggtgcagtt acttatgtgc aaaaggcaga agatatcatg gactttttaa
    19141 ttataattgg tgccatgtcc tgcaaagaag actttgaagc catcaaatta cttcgagaag
    19201 ctcgaaatga tattaaccgt gccaataatg cagaaacagc taatattgcc aaaactatca
    19261 gtgctagcat gaaaaccatt aataatatta ttaaaatcat ggacacaatt ggtttagaaa
    19321 gtttaccgat tgaattgcaa caggtagccc agcttcgggt taagcatcca gactattcca
    19381 ttcaacaagt tgctgatgct cttgagttcc caatcaccaa gagcggggtc aaccatcgct
    19441 tgcgtaaaat caataaaatt gcagatgact tatagaacat ttttatcgta tgagcctttg
    19501 ttcatacgat ttttttgtct aaaagtcgtt ttccattgtt tttttgaagt gtctgatgtt
    19561 ctgtgatatg ataaaaggga taataacgtt tgtaaaggag actgataatg gcatgtacaa
    19621 ctatactagt cggtgctcct aaatgctgta attttacaat ttaaaaataa cgttgatttc
    19681 atcacgttta acttctacac gtttaattaa tgttttaact attttctttt ggtcgtcgta
    19741 ggacattttg aaaacatcgt ccattttggc gactttctca aaagctggtt tattatttat
    19801 ctttctctta ttgttattta taaacgtttc caagctggat ttctctttaa ggagttcagc
    19861 gcttttttgt tttaacgctt ccatagaaat gagctcattt atatataaat cgtttagctt
    19921 tgaaagtttg gtttctagtt tttttaatcg ttcttggtga gctgttatat tttcttcagg
    19981 cttatctctg tacagtgatt ctattgattt agggtttaac tgtaatttgc ttatctcatt
    20041 caagacatat ctttcaacat ctttgacatc gtagcgtcct gactctttac attgctcacc
    20101 atcgttatag attgccgtct ttatccgttt tggatttctg ttgatacaag tgtatgtacg
    20161 ttttctagtg ccgtctttgc gaggtttgta gctatctatt tttaaaggcg ttccgcaata
    20221 tccacatttt gcaatgtttg aaagcatgta aagcccttga aaaggtctag tattatcttt
    20281 cttacttgtc cgctcttcca aagctttttg agctttataa aatatttctt ctgtcaatat
    20341 aggcgcgtgc tctccgtcaa aaatttcatt gcgatacttc actttgccga tgtaggttat
    20401 gttttctaaa attcgtttta ctttgacgtg agtccatttc ccgtcgtaat tttcacgcat
    20461 gtatgttgtt attcccatga ttgaccaacc agaaataatt ttgttaaaca tatcacggac
    20521 aatctcggct tggtaatggt caacagtcat cgactgagtg ttggtatcgt atttgtagcc
    20581 aaagggtggc gttgtccaag aagttgtttt ccctgacttt gctcgtcctt ttacacccaa
    20641 ctgcatacgc tcttttattt gttctctctc aaactcagcg atagcagaaa gaagcgtgat
    20701 gaacaagttt cccatagctg atttagtatc tatgttttct tgtaagctaa caaaatcgac
    20761 gttattagca ttaaatacgt ctttgactag ataaagcgtg tctctgacgt ttcggcttaa
    20821 acggtcaagc ttatatacga ctacagtgtc aaatttgcca gatttagcgt cttgtatcat
    20881 tttttgcatg gctggtcgtt ctagcttacc gccagaaaag ccgccatcag aatagttgtc
    20941 gtaaataacc caacccatag cttgacaata ttttgttaaa gcttcaattt gttgaccgat
    21001 tgaataacct tcctcggctt ggtgtagtgt agagacacgg ctatatatag ctacttttcg
    21061 ttttgtttgc attgatttat acctcatttc tgtgttaaaa tgggtatagt aaagagacct
    21121 actaaaagta ggctttttac tatactacca attattagct cacgctctcc tcgtccaaaa
    21181 tttgagcgtg ggcttttttt gtttatttta atcttcgtct tctaaatgtt taatagcgta
    21241 gttggcttct gattttgtaa aacctccgcc atcctcttcg ctaagcaatg tttctttgat
    21301 tttctcttta gacatgccat aatcttgaaa atttttagca gatgccaagg cattcttttt
    21361 ccaactgatt ttcagttttt ttacagcata atctaccgct tttttctcaa agccactttc
    21421 atcttgcaat gcttgataga aagctttttt agacatgttt gcgtctttca tcagctcagc
    21481 tgtttcaaga gcgtttttat actcttttga tacggcgtaa gctgtatgag cttgagggaa
    21541 aacagttgtc tcaatagcag gactggcgac aaacaagaaa gctgtagcaa tgataatagc
    21601 agttttcttc ttcattgtat ttctccagca gcttttaacg tggttcagtc ttttgcacgt
    21661 agtttttagt cacttaacct atgggcagct ttttctttta gaatagctat tttttcttga
    21721 tagtcattta cttttgcgag gtcgctgtta ccttcgttta tgtagtagtt gatttgatcg
    21781 tgtacatctt gagcagtagc agtagaagta gaaggtatgt tgagagagtt gaaaaagtct
    21841 accaactttt tacaatgatt tgcgtgagct ttatagtatg ttagttccat ttgatacaat
    21901 tttaactcaa attgttcttt gtcccatgac ggaaaatcga tatcaagatt cgttggatac
    21961 tgttttacaa catggatttc ccataaagct ttgtatttat cgtaaactgt ttgacctttt
    22021 tctgttaata gcgttttttc ttctatatct actagaagac cgttggattt aaaatcatta
    22081 gtcaatttct cagcatttaa attgtaacta taaaaaaagt atttaggaat agttacagta
    22141 gattttcgac cattctttgg atttccccac cacactaata gtaaaagttc tctcaatttg
    22201 tagttctcgt tagtgataaa actatcgtca tactttggaa aattgtgagg tctaccgtaa
    22261 atttcaaata tattaggtct tgtatctaat attttgaaat attctggggt gtagtagtca
    22321 aattcatccg aagatgaaaa tgtcatagaa gtttttggct gtatatttgt tcttttttta
    22381 ccaaataaaa ggctaagtaa tcccatattt taatcctctc tataaatatc aacgacttct
    22441 ccgattgttc ggatgtcgtc gttctctgat aagtagattt cttcgtattt atcatttaga
    22501 ctttgcaaat accatctacc gtcatagtca catttaagtt ttttgacaaa gtttttgtta
    22561 ttaacctgga aaataccaat ctcattaggc tcaatctgac tagttacttt aatgaacaac
    22621 aagtcattgt cttgtatcaa tggttccatt gagtcaccag ccactttagc gatagtgtca
    22681 tattcttctg ggacatcatc agctcttaac ttgacttcca tgtataagtt atcacattgg
    22741 aaaacaccat gtccagcagc taccaatccc tgaacatagt cggtgatgta tttgtcatcg
    22801 tcttcttttt tactaaagat agaagaaaca gtattttctt gctcctgttc agcgagttga
    22861 tcactagcaa agttcaagac ctttttttgt ctattttcgt ttagtttttc atatatagaa
    22921 a
//
LOCUS       DATWEK010000029        20716 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.029, whole genome shotgun sequence.
ACCESSION   DATWEK010000029 DATWEK010000000
VERSION     DATWEK010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20716
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.029"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            152..1135
                     /gene="guaC"
                     /locus_tag="VCR92_001341"
     CDS             152..1135
                     /gene="guaC"
                     /locus_tag="VCR92_001341"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEP4268404.1"
                     /translation="MFNDIPVFDYEDIQLIPNKCIITSRSQADTSVTLGKYQFKLPVI
                     PANMQTIIDETIAERLAKEGYFYIMHRFDEDSRKPFIKRMHEQGLIASISVGVKACEY
                     EFVTSLKEDAPEFITIDIAHGHANSVIDMIKHIKTELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMVMIGSLFAGHIESPGKTVEVDGETFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLSDTLTEMQQDLQSSISYAGGKDLDSLRHVDYVIVKNSIWNGDSI"
     regulatory      1258..1353
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            1440..2021
                     /locus_tag="VCR92_001342"
     CDS             1440..2021
                     /locus_tag="VCR92_001342"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEP4268405.1"
                     /translation="MQLLEERILTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQ
                     KYAEAGITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGVGIVIEKSFQD
                     GRRLIEDMGIEVTSLARIKNFENGNLNFLEADA"
     gene            2021..3304
                     /locus_tag="VCR92_001343"
     CDS             2021..3304
                     /locus_tag="VCR92_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEP4268406.1"
                     /translation="MTHSTKQEHSHSQSAVLGLQHVLSMYAGSILVPIMIAGALGYSA
                     RELTYLISTDIFMCGVATFLQLKLTKHTGVGLPVVLGCAFQSVAPLSIIGAQQGSGAM
                     FGALIASGIYVILVAGIFSKIARFFPPIVTGSVITVIGLSLVGVAMGNMGDNVKEPTA
                     QSMMLSLLTIVIILLVQKFTKGFVKSISILIGLVVGTLVSAMMGLVDTTPVVEASWIH
                     VLTPFYFGMPTFEITSIVMMCIIATVSMVESTGVYLALSDLTNDQLDEKRLRNGYRSE
                     GIAVFLGGLFNTFPYTGFSQNVGLVQISGIKTRRPIYYAAGILVVIGLLPKFGAMAQM
                     IPSPVLGGAMLVLFGMVALQGMQMLNRVDFQKNEYNFIIAAVSISAGLGFNGTNLFAS
                     LPETAQMFLTNGIVIATLTSVVLNLVLNGKDKQDE"
     gene            complement(3368..4306)
                     /locus_tag="VCR92_001344"
     CDS             complement(3368..4306)
                     /locus_tag="VCR92_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEP4268407.1"
                     /translation="MFVTQQLKLMGTVIDIQIESDKACQQLSRVIDLLYTYKNRFSAN
                     DSNSELMAINQAAGVKPLSVHSDLFNLIQIGKAHSLSTPSNLNIAIGPLVQAWRIGFE
                     DARVPSHNLISQQLALTDPRQVLIDDKKQTVFLQQVGMALDLGALAKGYITDKIMAYL
                     IEDGIDSALINLGGNVRVHGPNPKSPDKTFRIGIQKPDAKRGQHLGVIKVNNHSVVTS
                     GIYERQFTAKGKQYHHILDRQTGYPIETDMLSLTIMAPSSFYCDIWATRLFGLDSSMI
                     ITLLNTFDNIEGLLVTRKHHVLMSNGLRHYFQPYYH"
     gene            complement(4359..4544)
                     /locus_tag="VCR92_001345"
     CDS             complement(4359..4544)
                     /locus_tag="VCR92_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEP4268408.1"
                     /translation="MPFVTIDLFEGRSQEQKNQLAREVTEVVSRIAKAPKENIHVFIN
                     DMPEGTYYPQGEMKQKS"
     gene            4682..5251
                     /locus_tag="VCR92_001346"
     CDS             4682..5251
                     /locus_tag="VCR92_001346"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEP4268409.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGK
                     PVYEGDQIQIGGNETYIPVCRKHYFNPEI"
     gene            5286..6365
                     /gene="prfA"
                     /locus_tag="VCR92_001347"
     CDS             5286..6365
                     /gene="prfA"
                     /locus_tag="VCR92_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEP4268410.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTR
                     ETVTAYREYKQVIQTISDAEEMIKDASGDPELEEMAKEELKESKAAKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKMDEVIDALVMYDQTKKLESLNN"
     gene            6365..7204
                     /gene="prmC"
                     /locus_tag="VCR92_001348"
     CDS             6365..7204
                     /gene="prmC"
                     /locus_tag="VCR92_001348"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEP4268411.1"
                     /translation="MNYATLIRTYEDKLEQIDEDRENLSYVFREIKEWSSLDMLIHQN
                     QAVTPEDAVLLEHIFCSLSQHLSPQYITGNAYFRDLKLAVDKRVLIPRPETEELVDMI
                     LAENLDAPLNVLDIGTGSGAIAISLKKERPNWQVTASDISRAALDLAKANADAYQLDI
                     TFIESDVFSLISGTFDIIVSNPPYISYEDKEEVSLNVLQSEPHLALFAKENGYAIYRK
                     IIEQADNYLTKEGKLYFEIGYKQAEGIKDMLQAYFPQRHIRVVTDIFGKERMVVVDYG
                     VSS"
     gene            7188..7778
                     /locus_tag="VCR92_001349"
     CDS             7188..7778
                     /locus_tag="VCR92_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEP4268412.1"
                     /translation="MEYLASIIESGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRP
                     RDKAMNLNVADFNSILAFSKEQPRYLKKLYQAFLPGPLTIILKANDQVPYWINSGLST
                     VGFRLPSHPITTALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLT
                     GKDSTILDLSGERAVILRQGAITKEELLANVPELRF"
     gene            7796..8248
                     /locus_tag="VCR92_001350"
     CDS             7796..8248
                     /locus_tag="VCR92_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP4268413.1"
                     /translation="MLRPLSKTDCPMLQEINAKALGYLVSLDLLERQYERLIEDCHHY
                     FLAYADKDTNQLLGYVHAERYETLYASDGLNLLGLAVLPAYQRRGIGSALLRALESQA
                     RQEGIAFIRLNSASHRKEAHAFYRNLDYADDKTQLRFIKNLQGDDNDF"
     gene            8238..9494
                     /locus_tag="VCR92_001351"
     CDS             8238..9494
                     /locus_tag="VCR92_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEP4268414.1"
                     /translation="MIFDKGNVEDFDKELWDAIHAEEERQEHHIELIASENMVSKAVM
                     AAQGSVLTNKYAEGYPGNRYYGGTECVDIVETLAIERAKKLFGAAFANVQAHSGSQAN
                     AAAYMALIEAGDTVLGMDLAAGGHLTHGSPVNFSGKTYHFVGYSVDADTEMLNYEAIL
                     EQAKAVQPKLIVAGASAYSRSIDFEKFRAIADHVGAYLMVDMAHIAGLVAAGVHPSPV
                     HYAHIVTSTTHKTLRGPRGGLILTNDEALAKKINSAVFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFKDYAQAIIDNTAAMAAVFAQDDRFRLISGGTDNHVFLVDVTKVIANGKLAQ
                     NLLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVKESQTIAHLIIKALVN
                     HDQETILEEVRQEVRQLTDAFPLYKK"
     gene            9501..10478
                     /locus_tag="VCR92_001352"
                     /pseudo
     CDS             9501..10478
                     /locus_tag="VCR92_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
     gene            10479..11077
                     /locus_tag="VCR92_001353"
                     /pseudo
     CDS             10479..11077
                     /locus_tag="VCR92_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
     gene            11087..12805
                     /locus_tag="VCR92_001354"
     CDS             11087..12805
                     /locus_tag="VCR92_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4268415.1"
                     /translation="MKRLRPYLKGYLKESILGPLFKLLEALFELLVPLLIANMIDISI
                     SQHNSQGILRVVLTLFGLATIGLLLSVTAQYFSSKAAVGFTRQMTDDLFKKIMFLSKE
                     DQDHLGYASLVSRLTSDSFQIQTGINQFLRLFLRAPIIVCGAMVMAYWISPSLTLWFV
                     MMVIVLLTLVFVMSHLLGPLYLLIRRETDHLVRLTSQQLQGIRVIKAFNQTQKELQAF
                     KQQNMLLSRHQYQAATLANVLNPMTFLVVNLTLLILIWQGSWQVAHRSLSQGMLVALI
                     NYLLQILAELLKMTMLMGTINQSVTAAKRINQVFVLADEVPLPLLKDGPISTHLLTIR
                     HLTFTYPGAAEPSLYDIQLSADQGEWIGIIGGTGAGKTTLIDLICQTYSQYSGEISLN
                     WQGEVPKTLTEWRNVIALVPQKAQLFKGTIRSNLLLGQSMPINDEELWRALELAQAKE
                     FVAALPEQLEAPVEAFGRHFSGGQRQRLAIARALLKPKPILILDDASSALDNETRGRL
                     FKALKEELSDVLVILVTQSIKNLQFADKILVLEQGHQLDFASHDQLKVSNALYQEMLA
                     LYVKGE"
     gene            12808..14535
                     /locus_tag="VCR92_001355"
     CDS             12808..14535
                     /locus_tag="VCR92_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4268416.1"
                     /translation="MIKTDHHLLKRVLQDLLKKPLPVCILVIASFVQVGLSVYLPVLI
                     GKAVDMSLSVNSWQTLKWLLGQMLVVIVVNTLIQWVMPLVYSRLLYQYSQQLKDKLLE
                     KIHRLPFAYLDRQTIGDLVSRVITDTEQLINGLQLVFNQFILGLLTILCTIIAMAQID
                     WLMLILVLVLIPSSLFLARFIAQKSFHYAQAQTKSRGNLAQFTEEVLRQEGLVQLFNA
                     QEQSICDYHVLNKTYCEASQKAIFYASTVNPATRFINSVIYALLAGLGAVRIMAGLFS
                     VGQLTTFLNVVVQYTKPFNDISSVLAEIQSSLACAQRLYDLLDIEIKEQEHFLTFKAS
                     AVKGQIDFEEVSFSYQKDRPLLKDINFSVPAGSKVAIVGPTGAGKSTLINLLMRFYEL
                     DAGSIKLDKVPIKCYAKEELRSITGMVLQETWLKDATVHELIAYGSEEASRGEVVAAA
                     KAAHAHFFIMQLPKTYDTYLSASDDALSQGQLQLLAIARMFLKKPKVLILDEATSSID
                     IRTEAVIQEALKELMRGRTSFIIAHRLSTIQSADLILVMDQGRLVEWGTHASLMSKNG
                     CYARLQKIE"
     gene            14776..16146
                     /locus_tag="VCR92_001356"
     CDS             14776..16146
                     /locus_tag="VCR92_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEP4268417.1"
                     /translation="MSKIVVVGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQIAGPEGLFYSDKEELESLGAKVYMESPVQSIDYDTKTVTALVDGKNHVE
                     TYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQ
                     LAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIDLFRNGAFLV
                     NKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTDLEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYD
                     KDSRRILGAQMAAREDMSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAKD"
     gene            complement(16305..17288)
                     /locus_tag="VCR92_001357"
     CDS             complement(16305..17288)
                     /locus_tag="VCR92_001357"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEP4268418.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDIDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFAKEEFASAAKN"
     gene            17479..19965
                     /gene="gyrA"
                     /locus_tag="VCR92_001358"
     CDS             17479..19965
                     /gene="gyrA"
                     /locus_tag="VCR92_001358"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEP4268419.1"
                     /translation="MQDRNLIDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLRDINKNTVNFQDNYDGSEREPVVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAESIDAVKMVMEHPDCTTRELMEVIPGPDFPTG
                     ALVMGRSGIHRAYDTGKGSIVLRSRTEIETTQTGRERIVVTEFPYGVNKTKVHEHIVR
                     LAQEKRLEGITAVRDESSREGVRFVIEIRREASATVILNNLFKLTSLQTNFSFNMLAI
                     ENGVPKILSLRQIIDNYISHQKEVIIRRTRFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDVIAQTELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LSDILAKPERIITIIKEEMDEIKRKYANPRRTELMVGEVLSLEDEDLIEEEDVLITLS
                     NKGYIKRLAQDEFRAQKRGGRGVQGTGVNNDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRTAKGLPIVNLLKLEDGETIQTIINARKEETAGKSFFFTTKQGIVKRTE
                     VSEFNNIRQNGLRALKLKEGDQLINVLLTSGQDDIIIGTHSGYSVRFNEASIRNMGRS
                     ATGVRGVKLREDDRVVGASRIQDNQEVLVITENGFGKRTSATDYPTKGRGGKGIKTAN
                     ITPKNGQLAGLVTVDGTEDIMVITNKGVIIRTNVANISQTGRATLGVKIMKLDADAKI
                     VTFTLVQPEDSSIAEINTDRENSISKNKDN"
     gene            19985..>20716
                     /locus_tag="VCR92_001359"
     CDS             19985..>20716
                     /locus_tag="VCR92_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEP4268420.1"
                     /translation="MVKKQKRRKIKSMSWARKLLIAVLLILGLALLFNKPIRNTLIAR
                     NSNKYQVTKVSKKQIKKNKEAKSTFDFQAVEPVSTESVLQAQMAAQQLPVIGGIAIPE
                     LGINLPIFKGLGNTELIYGAGTMKEEQVMGGENNYSLASHHIFGITGSSQMLFSPLER
                     AQNGMSIYLTDKEKIYEYIIKDVFTVAPERVDVIDDTAGLKEVTLVTCTDIEATERII
                     VKGELKTEYDFDKAPADVLKAFNHSY"
BASE COUNT         6410 a         3648 c         4298 g         6360 t
ORIGIN      
        1 ataagtaatc tataaaatga aaggtaagtt tttacctaaa tatacctcta atcatcagag
       61 gtcataggaa gattattttg tatagaggac ttagagaaga aggtgagaac tgacttgttt
      121 ttcttaatct atgttaaaag aggagaaact tatgtttaat gacatccctg tatttgatta
      181 tgaagatatt caactgattc ctaacaagtg cattattact agtcgttcac aagcagatac
      241 aagtgtgaca ctcggaaaat accagttcaa gctaccagtt atcccagcaa atatgcaaac
      301 cattattgat gaaacaattg ctgagcggtt ggcaaaagag ggttattttt atattatgca
      361 tcgttttgat gaagatagcc gcaaaccttt tatcaaacgc atgcatgaac aaggcttgat
      421 tgcatcaatc tctgttgggg ttaaagcttg tgaatatgaa tttgtgacct ctttgaaaga
      481 ggatgctcct gagtttatca ccattgatat tgctcatggt catgctaaca gtgttattga
      541 tatgattaag catatcaaga ctgaattacc agaaacattt gtcattgctg gaaatgttgg
      601 tacgccagaa gctgtacgag aactcgaaaa tgcaggtgct gatgctacta aagtaggcat
      661 cggtccaggc aaagtatgta tcactaaagt taaaaccggt ttcggtacag gtggttggca
      721 gctagcagca ctgcgctggt gcgcaaaggc agctcgtaaa cctatcattg ctgatggtgg
      781 gattcgcaca catggtgata ttgctaaatc catccgcttt ggagctagta tggtcatgat
      841 tggatcgctt tttgcaggac atattgaaag tcctggaaaa acggtagaag tggatggtga
      901 aacgtttaaa gaatattatg gctcggcgtc agaatatcaa aaaggcgagc ataaaaatgt
      961 agaaggcaaa aaaatcttat tgcctacaaa aggtcactta tcagataccc tgaccgaaat
     1021 gcaacaggat ttgcaatcgt ccatttctta cgcgggtggt aaagatttag acagtttgcg
     1081 tcatgttgat tatgttattg tcaaaaattc catttggaat ggtgattcca tttaaatgat
     1141 atggagttag ctaggaccag taaagaattt tttagcttaa tgctggagat gcttttatca
     1201 tatctctgta ggtattgaaa aaaataagaa acatggtaaa atagtaaatt atcataatga
     1261 attcaataat gacatactta tttatgctgt gaattggcgc agcgtctcta caagacacct
     1321 taatgtctaa caataagtaa gcttttaggc ttgcttggtt tttaaccttg caaagtgaga
     1381 aactcttata gtttctcact ttgcggcagg ctttttctat ttgaatcaaa aggagattta
     1441 tgcagttact tgaagaacgc atcttaacag atggcaatat tctaggagag aatattctaa
     1501 aggtagataa ttttttaact catcaagttg attaccggtt gatgaaagca attggtaaag
     1561 tgtttgctca aaaatatgct gaggctggca ttacaaaagt ggttacaatc gaagcttcag
     1621 gtattgcacc agccgtatac gctgcagaag caatggatgt tcctatgatt tttgcgaaaa
     1681 aacataaaaa cattaccatg acagaaggca ttttgacagc agaagtttat tctttcacta
     1741 aacaagtgac aagcacggtg tctatcgctg gtaaattcct atctaaagaa gacaaggttt
     1801 tgattattga tgacttttta gctaatggtc aggcagccaa aggcttgatc gagattattg
     1861 gtcaagcagg ggcacaagtc gtcggcgttg gtattgtgat tgagaaatct ttccaagatg
     1921 gtcgtcgatt gattgaagat atgggcattg aagtgacctc attagcacgt attaaaaact
     1981 ttgaaaatgg taatctaaac ttcttggagg ctgacgcata atgacacatt caacaaagca
     2041 ggaacattct cactcgcaat cagctgtcct tggcttacag catgtgcttt cgatgtatgc
     2101 cggatctatt ttagtaccaa ttatgatcgc aggtgcttta ggttattccg ctagagagtt
     2161 gacctacctg atttcgacag atattttcat gtgtggtgtg gctactttct tacagttaaa
     2221 gttaaccaag catacgggag tgggattacc agttgtttta ggatgtgctt ttcaatcagt
     2281 ggcacctcta tccattattg gagcgcaaca aggttcaggt gccatgtttg gagccctcat
     2341 tgcgtcagga atttatgtca ttttagtggc aggtattttt tctaagattg ctcgtttctt
     2401 cccaccaatt gttacaggat cggtcattac cgttattggc ttaagtctcg taggtgttgc
     2461 tatggggaat atgggagata acgtcaaaga gcctacggca caaagcatga tgttatcatt
     2521 gttgacgatt gtcattattc ttttagtcca aaaatttacc aaaggttttg tgaaatccat
     2581 ttccattttg attgggcttg tagtgggaac tttggtttca gccatgatgg gattagtaga
     2641 tacaactcct gttgtagagg cttcttggat tcatgtgcta accccatttt attttggcat
     2701 gccaactttt gaaatcactt ctattgtgat gatgtgtatc atcgcaacgg tttctatggt
     2761 tgaatcaaca ggtgtctact tagcgctttc agatttgact aatgatcaat tagatgaaaa
     2821 acgtttgcgc aatggttatc gctcagaagg gatcgcagtc tttctcggtg ggttatttaa
     2881 taccttccct tacactggtt tttctcaaaa cgttggactt gtccaaatct caggtattaa
     2941 aacccgtcgt ccgatttact acgcagcagg tatccttgtg gtcattggcc tactccctaa
     3001 atttggagca atggcacaaa tgattccaag cccagttctt ggtggagcta tgcttgttct
     3061 ctttggtatg gttgctcttc aaggaatgca aatgcttaat cgtgttgatt tccaaaagaa
     3121 cgagtataat tttattattg ctgccgtttc catctcagca ggtttaggct ttaatggcac
     3181 taatcttttt gccagcttac cagagacagc tcaaatgttc ttaacgaatg gtattgtgat
     3241 tgccactttg acatctgttg tcttaaattt agttttaaat ggcaaagaca aacaagatga
     3301 ataattaaaa aacggctaat tgagccgttt tttctgtgat cagttttgag caaaccgtta
     3361 acccctttta atgatagtat ggttgaaaat agtgtctcaa accatttgac ataaggacat
     3421 ggtgctttct tgttactaga agaccttcaa tattatcaaa ggtatttaaa agtgtgataa
     3481 tcattgagct atcaagacca aataaacggg tagcccatat gtcacaataa aaagaagaag
     3541 gagccatgat cgttaagcta agcatatctg tttctatagg atagcctgtc tgacgatcta
     3601 agatatgatg atactgtttc cctttggctg taaactgcct ttcataaatt ccagaagtca
     3661 caacagagtg attgttaacc ttgatgacac caagatgttg cccacgttta gcatctggtt
     3721 tttgaatgcc aattcgaaaa gtcttgtcag ggcttttcgg attaggtcca tgaacgcgta
     3781 catttccacc taaattaata agggcagagt caataccatc ttcaatcagg taggccataa
     3841 tcttatcagt aatataacct tttgctaagg ctcctaagtc taaagccatt cctacttgtt
     3901 gtaaaaagac agtctgtttt ttgtcatcta taagaacctg tctaggatct gttagagcta
     3961 actgttgtga gataaggtta tgactaggca ctctagcatc ttcaaatcca attcgccagg
     4021 cttgaacaag tggcccaatg gcgatattaa gattacttgg tgttgacaag ctatgagctt
     4081 taccaatttg gattaggtta aataaatcag agtgaacgct gaggggttta acaccagccg
     4141 cctgattaat agccatcaat tcagagtttg aatcattagc tgaaaaacga tttttgtaag
     4201 tatataataa gtcaatgact ctacttagtt gttggcaagc tttgtcagat tcgatctgaa
     4261 tatcaataac tgttcccatt agctttaatt gttgcgtaac aaacataatt agtcctcttt
     4321 ttagcagaat acccccacta aggagtgggg gaaggtcatt atgatttttg tttcatttca
     4381 ccttgaggat agtaagttcc ttcaggcata tcgttgataa aaacatggat attttcttta
     4441 ggtgcttttg caatgcgtga gactacttcg gtaacctcgc gagctaattg atttttttgt
     4501 tcttgtgagc gtccctcaaa caagtcaatt gttacaaatg gcataatgtt actcctttat
     4561 gttattgggc atcattgtaa cataatgctg tgaaaaagta tacactgttt tcaatggctg
     4621 ggaaaacttc agcctttgtg gtaaaatagg tagaatacta tagaaagtag gattttccgc
     4681 tttggctcaa ctctattata aatatgggac aatgaattct ggtaaaacca ttgaaatttt
     4741 aaaagttgct cataactatg aagaacaagg caaacctgtt gtcattatga caagtgctct
     4801 tgatacacgt gatggttttg gcatcgtctc aagccgtatt ggtatgcgac gagaagctat
     4861 ccccatttca aatgacatgg atattttcac atttattgcc caattggagg aaaaacctta
     4921 ttgtgtcctg attgacgaaa gccaattttt aagcaagcaa aatgtttatg atttggcgcg
     4981 tgtggtggat gagctaaatg ttcctgtcat ggcttttggt ttgaaaaatg atttccaaaa
     5041 caatcttttt gaaggttcaa aacatttgct attattggcc gataagattg atgaaatcaa
     5101 aacaatttgc caatactgta gtaagaaagc aaccatggtt ttaaggacag aaaacggaaa
     5161 acctgtctat gaaggtgatc agatacaaat tggtggtaat gaaacatata tcccagtttg
     5221 tcgaaaacat tattttaatc cagagattta aaaggtaatc ggttttaaag gagatacaaa
     5281 gaaaaatgaa tatttatgat caattgcagg cagttgaaga tcgttatgaa gagttaggtg
     5341 agttacttag tgatccagat gttgtttcag atacaaagcg atttatggaa ttatcacgtg
     5401 aagaagctaa tactcgagaa actgtcacag cttatagaga atataagcaa gtcattcaaa
     5461 ccatttcaga tgctgaagaa atgatcaaag atgccagtgg tgatcctgaa ttagaagaaa
     5521 tggctaaaga agaacttaaa gaatcaaaag cagctaaaga agagtatgaa gaaaaattaa
     5581 aaatccttct attacctaaa gatcctaacg atgataaaaa cattatttta gaaattcgtg
     5641 gtgctgctgg tggcgatgaa gcagcgcttt ttgctggtga tcttttaaca atgtatcaaa
     5701 aatatgctga aactcaagga tggcgttttg aagttatgga atcatccgtt aatggtgttg
     5761 gtggtattaa agaagtggtt gccatggttt ctggtcagtc agtttattct aagcttaaat
     5821 atgaatcagg agctcatcgt gttcaacgtg tcccagtgac agagagtcag ggtcgtgttc
     5881 atacttcaac tgcaactgtt ttggtaatgc cagaagttga agaagtagaa tacgacattg
     5941 atcctaaaga ccttcgcgtc gatatttacc acgcgtctgg tgctggtggt cagaatgtca
     6001 ataaagttgc tactgcagtt cgtatggtac acattcctac aggaatcaaa gttgaaatgc
     6061 aagaagagcg tactcagcaa aaaaaccgtg ataaagcgat gaaaatcatt cgtgctcgtg
     6121 ttgctgacca ttttgcgcaa attgctcaag atgaacaaga tgctgaacgt aaatcaacag
     6181 ttggtactgg tgatcgttca gaacgtattc gtacttataa tttcccacaa aatcgtgtaa
     6241 cagatcatcg tattggtttg acacttcaaa aattagatac tattttatct ggaaaaatgg
     6301 atgaagttat tgatgcactc gttatgtatg atcagacaaa gaaattagaa tctctcaata
     6361 actaatgaac tatgctacat taatcagaac ttatgaagat aaactagaac aaatagatga
     6421 ggatcgcgaa aatctctcct atgtttttag agaaatcaaa gaatggtcaa gtctagatat
     6481 gttgattcac caaaatcaag ctgtgactcc tgaagatgct gttcttttgg aacatatttt
     6541 ctgttctcta agtcagcatt tatctcctca atatattaca ggtaatgctt attttcgtga
     6601 tttgaagctt gcagtcgaca agcgtgtatt aattccaagg ccagaaacag aagaattagt
     6661 tgacatgatt ttagctgaaa atcttgatgc accgttgaat gttttagata ttggtacagg
     6721 tagtggagcg attgctattt ctctcaaaaa agaaaggcct aactggcaag taacggcatc
     6781 tgatatttct agagctgctc ttgacttggc aaaagccaat gctgatgctt accagcttga
     6841 tataacgttt attgaatcag atgtttttag tctcatttca ggaacatttg atattattgt
     6901 gtcaaatcct ccctacatat cctacgagga taaggaagaa gtcagtctaa atgttttgca
     6961 atcagagcct catttggcac tttttgctaa agaaaatggc tatgctattt accgtaagat
     7021 tattgaacaa gctgacaatt acttaactaa ggaggggaag ctttactttg aaattggtta
     7081 taagcaagct gaaggtataa aagatatgtt acaagcctat tttcctcaaa gacatatacg
     7141 agtcgtaacg gatatatttg gcaaagaaag aatggtggtt gttgattatg gagtatctag
     7201 ctagtatcat tgaatcaggt gatgcccttg ttttgccaac agaaacggtt tatggtcttt
     7261 ttgccaaggc tttagatgaa aaagcagtaa atgctgttta tgacttaaaa caaagacccc
     7321 gagataaagc aatgaacctt aatgtggctg attttaatag tatcttagcc ttttcaaaag
     7381 aacagccgag atacctcaag aaattatacc aagccttttt accaggtccg ttaacgatta
     7441 ttttaaaagc taatgaccag gttccttatt ggattaattc gggtctttca acggttggtt
     7501 ttcgcttacc cagtcatcca attaccacag ctttaattca aaaaacaggc cctttaattg
     7561 gtccttctgc aaacttatct ggcaaagcta gtggtcgagt ttttgatcat attatgcaag
     7621 attttgactt tcaagtgttt ggttatgcag atgatccttt tctaacaggt aaggattcaa
     7681 ccatcttaga cttatcaggt gagcgtgctg tgattttacg tcaaggtgct atcaccaaag
     7741 aagaattatt agccaacgtg cctgaacttc gcttttaaga gaggagccgc ttggaatgtt
     7801 gagaccatta agtaaaacgg actgtcctat gctacaagaa attaacgcca aagcccttgg
     7861 ctatttagtt tcgcttgact tgttagaaag gcaatatgaa cgattgattg aggattgcca
     7921 tcactatttt ttagcttatg ccgacaagga taccaatcaa ttattaggct atgttcacgc
     7981 tgaacggtat gagacccttt atgcttctga tggtcttaat ctcttgggct tggctgtttt
     8041 accagcctat cagagaaggg gaattgggag tgccttacta agggccctgg aatcccaagc
     8101 taggcaggaa ggcattgcct ttattcgcct caattctgcc agtcatcgta aagaagcgca
     8161 tgctttttac cgaaacctcg actatgcaga tgataaaaca caattacgat tcatcaaaaa
     8221 cttacaagga gatgacaatg atttttgata aaggtaatgt tgaagacttt gataaagagc
     8281 tttgggatgc cattcatgct gaagaagaaa gacaagaaca tcatatcgaa ttgattgcat
     8341 ctgaaaacat ggtttcaaaa gctgtcatgg cagctcaagg ttctgtttta accaataagt
     8401 atgcagaagg ctatccaggt aatcgctatt atggtggaac agaatgtgtg gatattgtcg
     8461 aaacgcttgc tattgaacgt gctaagaaac ttttcggtgc cgcatttgcc aatgttcaag
     8521 cccattccgg aagtcaagcc aatgcagcag cttatatggc cttgattgag gctggtgaca
     8581 ccgtattagg aatggatttg gctgcaggtg gtcatctcac gcatggctct ccagtaaatt
     8641 tttctggaaa aacctaccat tttgtgggtt actcagtaga tgctgatact gaaatgttaa
     8701 attatgaggc gattttagaa caagcaaagg cggtccagcc aaagcttatc gttgcagggg
     8761 cttcggccta ctctagaagc attgattttg aaaagtttcg tgccattgct gatcacgtag
     8821 gtgcttactt aatggtggac atggctcaca tcgctggcct tgtagcagca ggtgtgcacc
     8881 cgagtcctgt ccattatgcg catattgtga catcaacaac ccataaaacc ttacgtggtc
     8941 ctcgtggagg cttgatatta accaatgatg aagctcttgc taaaaagatt aattcggccg
     9001 ttttccctgg tttacaagga ggacctctgg aacacgtgat tgctgccaaa gcggttgcct
     9061 tcaaagaagc cttggatcca gcctttaaag actatgcaca agctattatt gataatactg
     9121 cggctatggc agcagttttt gcacaagatg atcgtttccg tctgatctca ggtggtacag
     9181 ataatcatgt ctttttagta gatgtcacta aggttattgc taatggtaaa ctagcgcaaa
     9241 atcttctgga tgaggttaat attactctaa ataaaaatgc cattcctttt gaaaccttat
     9301 ctccttttaa aacatcaggc attcgtattg gttgtgcagc tataaccagt cgtggcatgg
     9361 gagttaaaga aagccaaact atcgctcacc tcatcatcaa agccttggtt aatcatgatc
     9421 aagaaactat tcttgaagag gttcgtcagg aagtgcgtca gttaaccgat gccttcccac
     9481 tctataaaaa gtaaggaatc atgttagata gttatataaa acgtattgtc attcatcaat
     9541 tttctcccaa tgacactgag ttactgttat cagatcgttt agtgagcatt acaccacgaa
     9601 ttgatgaata tttccggaaa aaattggcta aagtgttctc ggatgaagcc aaacggggtc
     9661 agtttgaggc taataatacc ttttttacaa ccattggtga tgatttgttg gaaacgtctg
     9721 ttaccattgc ccagttatgg aaggaagcct ttgttatttc agaggatcaa aaaaccaatg
     9781 atttagtctt tgtccagttt gataaggatg gcgaaccctt ttttgctttc ttgcgaattg
     9841 ctttgaaaga acagtttgct cacctttctg acaattatga acatccattt acggtgacgc
     9901 agaataatct gccgagtccc acccagacac cagatgaagc actagtcatt aatctcaaat
     9961 ctggtcagta ctacttgatt gaaaagcgtg tgaagcataa tggcagtttt gctaattatt
    10021 tttcagaaca cctcttgaaa gttacacctg agcaatctgt taaaaagtct atcaaaatga
    10081 tagaacaaac cgctcaaaaa attgcagagc attttaatca agatgatttt acttttcagt
    10141 caaagatgaa atccactctt tttaagcagt tagaagcaga cgacgtttta tcaccagaaa
    10201 aattagctga ccaactcttt gatgataatt taacagcccg tttaaccttt gtggattaag
    10261 tcaaagatgt cattccagaa cctataaaaa ttagcgatat tgatcattct agacagataa
    10321 aaaaactaga aaatcaaaag ctatcgttat caaacgggat agaattaaca gtaccaaatg
    10381 ccatttatca ggatgctgaa gcggttgaat ttttgttaaa tgatgatggg acttattcaa
    10441 tcttgattaa aaatatagag gacattaaaa ccaaatagat gtttagactt ttaaagcgtg
    10501 cctgcagttt tcttcttctt tttgtcattt atcaatcctt tgttattcat cacaatgttc
    10561 aacgtgtttt ggcatataag cctatggttg agaaaacatt agcagaaaat gatacaaagg
    10621 caaatgtaga cttagtctta gctatgatat acaccgagac aaaaggagga gaagcagatg
    10681 tcatgcaatc cagtgaaagc agttcaggac aaaaaactcg attacagata gtcaggccag
    10741 tattgagcac ggggtgaatt tactgtctca taatcttgct ctagctgagg aagcaggagt
    10801 agattcttgg acggctgttc aggcctataa ttttggaaca gcttatattg attatattgc
    10861 taaacatgga ggtcaaaata ccgttgattt agcgactacc tattccaaaa ccgttgtggc
    10921 gccaagccta ggcaacacta gtggtcaaac ctatttttat taccaccccc tcgccttgat
    10981 ttctggaggt aagctttata agaatggcgg caatatctat tactcacgag aagttcattt
    11041 caatctttat ttaattgaac tgatgagcct tttttagaaa gttatcatga aacgattacg
    11101 tccatatttg aaagggtacc taaaagaaag tatcttaggt cctcttttta aattattaga
    11161 agctttattt gaattattag tccctttgtt aattgctaat atgattgata tatcgattag
    11221 tcaacacaac agccagggaa ttttgagggt tgttttaaca ttatttggtt tagcaaccat
    11281 tggcttattg ctttccgtta cagcccagta tttttcttcg aaagcagctg ttggttttac
    11341 aagacaaatg acagatgatt tgtttaaaaa aatcatgttt ttgagcaagg aggaccaaga
    11401 ccatcttggt tatgctagtc tggtatcacg attgaccagt gatagttttc aaattcaaac
    11461 tggtatcaat caatttttgc gtctttttct aagggcccct attatcgtat gtggtgctat
    11521 ggtaatggct tattggatta gtccaagtct aaccctatgg tttgtgatga tggtgattgt
    11581 cttactaaca cttgtttttg ttatgtcaca tttattaggt cccctttatc tcttaatccg
    11641 ccgagaaaca gatcacttgg ttcgtttgac tagccaacag ttacaaggaa tccgagtaat
    11701 taaggctttt aatcaaaccc aaaaagaact ccaagcattt aagcagcaaa atatgctctt
    11761 aagtcgccac caatatcaag ctgctaccct agccaatgtc ttgaatccta tgactttttt
    11821 agtggtcaat cttactctgt taatcttgat ttggcaagga agttggcaag tagctcatag
    11881 atcgcttagt cagggcatgt tggttgcttt aattaattac ctcttgcaga ttttggcaga
    11941 acttttgaaa atgaccatgt tgatgggaac catcaatcaa agtgtaacag ccgcaaaacg
    12001 gattaatcag gtgtttgttt tagctgatga agtgcctttg cccttactta aagatggtcc
    12061 tatttcaact catctgttga ccatccggca cttgaccttt acttatccag gagcagcaga
    12121 gccaagtctg tatgatattc agttaagtgc tgatcaggga gaatggattg gcatcattgg
    12181 tggtactgga gcaggcaaaa cgactttgat tgacttgatc tgccaaactt attcacaata
    12241 tagtggtgag attagtctta attggcaagg agaagtgcca aaaacactaa ccgagtggcg
    12301 aaatgtgatt gctcttgttc ctcaaaaagc tcaattattt aaaggaacga ttagaagtaa
    12361 cctcctactg ggacaatcaa tgcctattaa tgatgaggag ctgtggcggg ctcttgaatt
    12421 agctcaagca aaagagtttg tcgctgcctt accagaacaa ttagaggcac ctgttgaagc
    12481 ctttggccgt catttttcag gagggcaacg gcaacgtcta gctattgcca gagcacttct
    12541 gaagccaaaa cccattttga ttttggatga tgccagttcc gccttagaca atgagactcg
    12601 aggacgactt tttaaagctc taaaagaaga gttatcagat gttttagtga ttctagtcac
    12661 gcaatccatt aagaatttgc agtttgctga taagatttta gtgttggaac agggccatca
    12721 attggatttt gccagtcatg accagttaaa agtaagcaat gcactttatc aagaaatgct
    12781 agcgctttac gtgaaggggg agtaaaaatg attaaaacag accatcacct cctaaagcga
    12841 gtgcttcagg atttgttaaa aaaacctcta cctgtttgta ttctcgtgat agctagtttt
    12901 gtacaagttg gtttaagtgt ttacttgcct gttcttatcg gtaaagccgt tgatatgagt
    12961 ttgtcagtca attcttggca aactttaaaa tggctgttgg ggcaaatgtt agttgttatt
    13021 gtggtcaaca cattgattca atgggtgatg cctcttgtct atagtcgttt gctatatcaa
    13081 tatagccagc aattgaaaga taagcttttg gaaaaaattc atcgtcttcc ttttgcatat
    13141 ctagatcgtc aaaccattgg agatttggtt agtcgagtga taaccgacac tgagcaactg
    13201 atcaatggtc tacaattggt ttttaaccag tttatacttg gactattgac gattctgtgt
    13261 accattatag ctatggcaca gattgactgg ctcatgttaa tcttggtttt ggtgttaata
    13321 ccaagctccc tctttttagc tcgttttatt gctcaaaaga gttttcatta tgcacaagca
    13381 cagaccaaaa gcagaggaaa tttagctcag tttactgaag aagtccttcg tcaagaaggt
    13441 ttggttcaac tgtttaatgc tcaagagcag tctatctgtg attatcatgt tttaaataaa
    13501 acctattgcg aggcttcaca aaaagccatt ttttacgcct caacagtcaa tccagccact
    13561 cgctttatta atagtgtcat ttatgcttta ctggcaggtt taggggctgt tcgtatcatg
    13621 gctggacttt tttcagtagg tcagctaacc acttttttaa atgttgttgt ccaatatacc
    13681 aaacctttca acgatatttc atctgtcttg gcagagatac agagttcttt agcttgtgcg
    13741 caaaggcttt atgacctttt agatattgaa ataaaagagc aagagcactt tctaacattt
    13801 aaggcatcag cggttaaggg acaaattgac tttgaagaag taagtttttc ttatcaaaaa
    13861 gacaggccct tactgaagga tattaatttt tctgttcctg cgggttccaa ggtagcgatt
    13921 gtagggccta caggtgcagg caaatcgact ttaatcaatt tactcatgcg cttttatgaa
    13981 cttgatgctg gtagcatcaa gttagataaa gttcctatta agtgttatgc taaggaagaa
    14041 cttaggtcca ttactggcat ggtattgcaa gaaacctggt tgaaagatgc gactgttcat
    14101 gagttgattg cttacggcag tgaagaggct agccgtggtg aagtagtggc agcagccaaa
    14161 gcagctcatg cacacttctt tattatgcaa cttcctaaga cttatgatac ttacttaagt
    14221 gcttctgatg atgctttgtc ccaagggcag ctccagttat tagctattgc cagaatgttt
    14281 ttgaaaaaac caaaagtctt gattctagat gaagccacct cctctattga tattagaaca
    14341 gaagctgtta ttcaagaggc actaaaagaa ctcatgagag gaaggaccag ctttatcatt
    14401 gcccatcgtt tatcaacgat tcaatcagct gatttgattc ttgttatgga tcaaggtcga
    14461 ttggttgagt ggggaacaca tgccagctta atgtcaaaaa acggatgtta tgctagatta
    14521 caaaagatag aataaagttc gtcttttaac aaaggtgaac tttttaagtc ttcctaaagt
    14581 tagttaatta acaaacttta aactgttata taaaaaaata acagcgaaaa agcggacgat
    14641 ctttttttat aagtgagaaa aaacagttga ctaaagaaga aataactcaa aaaagtgagc
    14701 aatatatttg gaagcgtttt ttgactgtgg tataatagag ccctatataa tattgtgaaa
    14761 tgaggaacaa aatatatgag taaaatcgtt gttgttggtg caaaccatgc tggtacggcc
    14821 tgtatcaaga ctatgttaac aaactacggt gatgctaatg agattgttgt atttgaccaa
    14881 aactcaaata tttcattttt aggctgtggt atggcacttt ggattggtga gcaaattgct
    14941 ggaccagaag gacttttcta ttcagataaa gaagaattag agtctttagg ggctaaagtt
    15001 tacatggaat cacctgttca atcaatcgac tacgatacca aaacagtgac agcgcttgtt
    15061 gatggtaaaa accacgtgga aacttacgac aagttgattt ttgcaactgg ctcacaacct
    15121 atcttaccac cgattaaagg tgccgaaatc aaagaaggat cacttgaatt tgaagcaact
    15181 cttgaaaatc ttcaatttgt gaagttatac caaaactcag ctgatgtgat tgcaaagctt
    15241 gaaaacaaag acattaaacg tgtagccgta gttggtgctg gttacattgg tgttgagtta
    15301 gctgaagctt tccaacgcaa aggcaaagaa gtggttctga ttgatgtcgt ggacacttgc
    15361 ttggcaggtt attacgaccg tgatttgact gacttaatgg ctaaaaacat ggaagaacat
    15421 ggtattcaac tagcctttgg tgaaacagtt aaagaagtag ctggtaatgg taaggttgaa
    15481 aagatcatta ctgacaaaaa tgagtacgat gtggatatgg ttatcctcgc cgttggtttc
    15541 cgtccaaaca caactcttgg aaatggtaag attgatcttt tccgtaatgg tgctttcctt
    15601 gtcaataaac gccaagaaac ttctattcca ggtgtttatg ctattggtga ctgtgcaact
    15661 atctacgata atgctactcg cgatacaaac tacattgctt tagcttcaaa tgctgtccgt
    15721 acaggaattg tagcagcaca taacgcttgt ggtacagacc ttgaaggtat tggcgttcaa
    15781 ggttcaaacg gtatttccat ttacggcttg cacatggtat caactggttt gactcttgaa
    15841 aaagctaaac gacttggttt tgatgctgca gtgactgagt atactgataa tcaaaaacct
    15901 gaatttatcg aacacggtaa cttcccagta accattaaga ttgtttacga taaagactca
    15961 cgtcgtatct tgggtgctca aatggcagcc cgtgaagata tgtcaatggg aattcacatg
    16021 ttttcacttg ctatccaaga aggagtgacc attgaaaagt tggcattaac tgatattttc
    16081 ttcttaccac atttcaacaa accttacaac tacatcacaa tggcagcact tggtgccaaa
    16141 gactagtatc tgataggaaa aagccagagc agttcagcag cactggcttt tttgcttttt
    16201 aattgttgca acctgaaaag ttctaaactt atgattatcc tcttatagca cgttggaaaa
    16261 ggaatatcag gcaaaacaaa aagagaccga agtctctttt gtgattagtt tttagcagca
    16321 gaagcaaatt cttccttagc aaaggcttca tcaatgatag ctttcaattg atttgcagag
    16381 gcttgcattt tttgcaattc agcatcgtta agtggaatgt ttactggacg aacaattcca
    16441 tacgctccaa cgatagctgg ttgaccaata tagcaatctt caacaccttc gtattggcct
    16501 tcttggaaaa cagaaagcgg aagaacagca ttttcatcat caagaatagc ttttgtaata
    16561 cgagctaggg caactgcaat accgtagaaa gtagcacctt ttttattgat gattgagtaa
    16621 gcagcatcac gtacagaaat gaaaagatca actaggcctt gctcatcaat gtcacgatta
    16681 gcttggagcc agtcgtaaag acctacacca gcaacgttag cgtgtgacca aacagcaaat
    16741 tcagagtcac cgtgttctcc catgatgtaa gcgtgaaccg aacgcgcatc aacaccgatt
    16801 ttagcagcca gagcttgacg gaaacgggct gaatctagag atgtacctga accaatgaca
    16861 cgctctttag ggaaacctga gaatttccat gttgagtaag tcaaaacgtc aactgggtta
    16921 gcagcaacaa gaaagattcc tttgaaacca gatgcaacga tttgtgtaac aacctcttta
    16981 ttgatacgaa ggtttttttc aaccaggtca aggcgtgttt cacctggttt ttgaggagca
    17041 ccagctgtta agacaacaag atcagcatca tgacagtctg agtagtcagc tgcatagatt
    17101 tttttaggtg atgtaaaagc tagagcgtgg cttaaatctt ctgcatctcc ttgagttttt
    17161 tctttaaaaa tatcaataat accaagttct tgagcaatat tttgtgttac caatgcaaaa
    17221 gcgtatgatg aaccgacggc accatcaccg accaagatta cttttttgtg ttgtttagtt
    17281 gcagtcattt ctaaacatct ccttaatttt attagagcaa aagctcatac ggtcttattt
    17341 taacatattg ataattgttt gtcattgaat tcagaaaaat aatgaaaata gtttactgat
    17401 aacgcttcca ataagaaaaa ataaggaatt tatggtataa tgaaatctag tattgactag
    17461 aaaaggagca ttccttaaat gcaagatcga aatttaattg acgtcaatct gacaagtgaa
    17521 atgaaaacga gtttcattga ctatgccatg agtgtcattg tggcaagagc tttgccagat
    17581 gtgcgtgatg gtctgaaacc tgtgcatcgt cgtattctct atgggatgaa tgaactcggt
    17641 gtgacacctg ataaaccgca taaaaaatct gctcgtatta cgggtgatgt catgggtaaa
    17701 tatcacccgc atggggattc ttctatttat gaagctatgg ttcgtatggc tcagtggtgg
    17761 agttatcgcc atatgcttgt tgatggccat ggcaattttg gttctatgga tggtgatggt
    17821 gctgccgctc aacgttatac tgaagcgcgc atgagtaaaa ttgcgcttga attattaagg
    17881 gatatcaata aaaataccgt taattttcaa gataactacg atggaagcga aagagaacca
    17941 gtagtattac cagctcgctt tcctaattta ttagtcaatg gagcgacagg gattgccgtt
    18001 gggatggcaa ctaacattcc gcctcataat ttggcagagt ctattgatgc tgtcaagatg
    18061 gtaatggaac atccagactg tacaacaaga gagttgatgg aagtgatccc tggacctgac
    18121 tttccgactg gtgcccttgt tatggggcgc tcaggtattc atagggctta tgatactggt
    18181 aaaggttcta tcgttttacg ctctcgaaca gaaattgaaa caactcaaac aggtcgggaa
    18241 cgtattgtgg ttactgaatt tccctatggc gtcaataaaa cgaaagtgca tgaacacatt
    18301 gttcgtttag cacaagaaaa aagactagaa ggtattacag cagttcgtga cgaatctagc
    18361 cgtgaaggag tgcgttttgt tatcgagatt cgtcgagagg catccgcgac agttatctta
    18421 aataacctct ttaaattaac aagccttcag acgaatttca gttttaatat gttggctatt
    18481 gaaaatggtg tgcctaaaat attgtcactc agacaaatca ttgataatta cattagtcat
    18541 caaaaagaag ttattatacg tcgcacccga tttgataaag ataaagctga agccagagct
    18601 catattttag aaggcttact gattgccctt gatcatttag acgaagtgat tgctattatt
    18661 cgtaacagtg agacagatgt cattgctcag acagaattga tgtcacgttt cgacttgtct
    18721 gaacgccaaa gccaagctat tttggatatg cgtttgcgtc gtttgactgg tttggaacgt
    18781 gataagattc aatcagaata tgatgatttg ttggccttga ttgctgactt atctgatatt
    18841 ttagccaaac cagaacgtat tatcactatc atcaaagaag aaatggatga gatcaagcgt
    18901 aaatacgcta acccacgccg tacagaatta atggtcggtg aagtcctttc tctagaagat
    18961 gaagacctaa ttgaagaaga agatgttttg attaccttgt caaataaagg ttatatcaag
    19021 cgtcttgctc aagatgaatt tcgtgcccag aagcgtggtg gacgtggcgt ccaaggaact
    19081 ggagtcaaca atgacgactt tgtccgtgaa ttggtatcaa caagtaccca tgatactttg
    19141 ctcttcttta cgaattttgg gcgtgtctat cggttgaaag cttacgaaat tccagaatat
    19201 ggtcgtacag caaaaggtct tccaattgtt aatctattga aattagaaga tggtgaaacc
    19261 attcaaacta ttatcaacgc acgtaaggaa gaaacagcag gtaaatcctt cttctttaca
    19321 acgaaacaag gcattgtcaa acgtacagaa gtttcagaat ttaataatat ccgtcaaaac
    19381 ggtctccgtg ctcttaagtt gaaagaggga gatcagctga ttaacgtcct tttgacaagc
    19441 ggtcaggatg atattatcat tggaactcac tccggatatt ctgttcgttt taatgaagca
    19501 agcatccgca acatgggccg atcagctacg ggtgttcgcg gggttaagct tcgtgaagat
    19561 gatcgcgttg ttggcgcgtc acgtattcaa gataaccaag aagttcttgt aattaccgaa
    19621 aatggctttg gtaagagaac aagtgctaca gactatccta caaaaggtag ggggggaaaa
    19681 ggaataaaaa cagctaatat tacccctaaa aatggtcaat tagctggatt ggttaccgta
    19741 gatggtacag aagatatcat ggtgattaca aataaaggtg tcattattcg cacaaatgtt
    19801 gcaaatattt cgcaaacagg tcgtgctact ttgggtgtta aaattatgaa actagatgct
    19861 gatgctaaga ttgtaacatt taccttggtt cagcctgaag atagtagtat cgctgaaatc
    19921 aatactgatc gtgaaaatag tatttcaaaa aataaagata attaatcata acaaggagta
    19981 aaaaatggta aaaaaacaaa agcgtcgaaa aataaaatcc atgtcttggg caagaaaact
    20041 actaatagct gtacttttaa ttctaggttt agcattgctt tttaacaaac ctatccgaaa
    20101 tacattaatt gctcgaaact ctaataaata tcaagtaacg aaagtttcga aaaaacaaat
    20161 caaaaagaat aaagaggcta agtcaacatt tgatttccaa gccgtagagc cagttagtac
    20221 agagagtgtc ttgcaagcac aaatggcggc tcagcaactt cctgttatag ggggcattgc
    20281 cataccagag cttggcatta atttaccaat ttttaaaggt ttaggaaata ctgagcttat
    20341 ttatggcgca ggaacgatga aagaagaaca agttatggga ggagaaaata attattctct
    20401 tgccagtcat catatttttg gaattacagg ttcatctcaa atgctctttt cgccgcttga
    20461 aagagcacaa aatgggatgt ccatctattt aacagataaa gaaaaaattt acgaatacat
    20521 cataaaagat gttttcacgg tagctcctga acgcgttgat gttatcgatg atacagctgg
    20581 tctcaaagaa gtgactttag tgacttgtac agatatcgaa gcaacagaac gtattattgt
    20641 caaaggagaa ctaaaaacag aatacgattt tgataaagcg cccgccgatg tattgaaagc
    20701 ttttaatcat tcttat
//
LOCUS       DATWEK010000030        20427 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.030, whole genome shotgun sequence.
ACCESSION   DATWEK010000030 DATWEK010000000
VERSION     DATWEK010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20427
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.030"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            542..931
                     /locus_tag="VCR92_001360"
     CDS             542..931
                     /locus_tag="VCR92_001360"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEP4268421.1"
                     /translation="MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIE
                     NVSFGLTNCGERTAIFKAISDGHKELVEIAIYGETMQPVSPCGACRQVMAEFFAPSSL
                     VTLIAKNGQTVEMTVGDLLPYSFTDLI"
     gene            1025..2077
                     /locus_tag="VCR92_001361"
     CDS             1025..2077
                     /locus_tag="VCR92_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEP4268422.1"
                     /translation="MNKKFIGLGLASVAVLSLAACGNRGASKGGASGKTDLKVAMVTD
                     TGGVDDKSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAVSGGYQLI
                     YGIGFALKDAIAKAAGDNEGVKFVIIDDIIEGKDNVASVTFADHEAAYLAGIAAAKTT
                     KTKTVGFVGGMEGTVITRFEKGFEAGVKSVDDTIQVKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQAAGGTGAGVFNEAKAINEKRSEADKVWVIGVDRDQKDEGKYTSKDGKEA
                     NFVLASSIKEVGKAVQLINKQVADKKFPGGKTTVYGLKDGGVEIATTNVSKEAVKAIK
                     EAKAKIKSGDIKVPEK"
     gene            2216..3748
                     /locus_tag="VCR92_001362"
     CDS             2216..3748
                     /locus_tag="VCR92_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4268423.1"
                     /translation="MTQHVIEMREITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGEIVINDKPVQIDSPSKSAKLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLNQASKDIKVLSEKYGLAINPSAKVSDISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIKELMTIMKNLVKEGKSIILITHKLDEIRAVAERVTVIRRGK
                     SIETVDVAGATSQDLAEMMVGRSVSFTTSKKAAEPKDVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVKSGSIMIKNKEVTHLSSRKITELS
                     VGHVPEDRHRDGLILDLSLAENTALQTYYKQPLSQNGILNYTKINDYARQLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRDPDLLIVSQPTRGLDVGAIEYIHKRLIKERD
                     KGKAVLVVSFELDEILNLSDRIAVVHDGKIQGIVLPENTNKQELGILMAGGSIHKEEG
                     HV"
     gene            3741..4805
                     /locus_tag="VCR92_001363"
     CDS             3741..4805
                     /locus_tag="VCR92_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4268424.1"
                     /translation="MSKNAQKIAVPLISVLLGFLLGAIIMVIFGYDPIWGYEGLFQIA
                     FGSVKNIGEIFRSMGPLILIALGFTVASRAGFFNVGLSGQALAGWISAGWFALLNPDM
                     PRPLLILMTALIGMIAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIVQRGY
                     PESVKQSIDSTIQVSDNASYQTHWLSALTNNSRINIGIFFAIIAIALIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSSKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     VGFDGMAVSLLAANSPLGIFFSSFLFGVLNIGAPGMNIAGIPPELVKVVTASIIFFVG
                     SHYLIERYIIRPKKLVKGGK"
     gene            4807..5763
                     /locus_tag="VCR92_001364"
     CDS             4807..5763
                     /locus_tag="VCR92_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4268425.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERSGVVNVGLEGI
                     MVMGAFSGIVFNLEFAETFGKATPWIAVLVGGIVGLIFSLIHAVATINFRADHIVSGT
                     VLNLLAPSFAVFLVKAMYGKGQTDNIQQSFGKFDFPGLSQIPVIGDIFFKNTSLIGYF
                     AIAFSFFAWFLLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPL
                     LEKIPTVYLQIAPYMVTIIILAAFFGQAVAPKADGINYIKSK"
     gene            complement(5981..7699)
                     /locus_tag="VCR92_001365"
     CDS             complement(5981..7699)
                     /locus_tag="VCR92_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEP4268426.1"
                     /translation="MTYTENFQKWLDFEQLPDYLRQELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIYVVRQATEGLAKLIETKGEEAKKHGVAIAYDSRHFSPEFAFE
                     SAQVLAQHGIKSYVFEALRPTPELSFAVRHLNAYAGIMVTASHNPAPFNGYKVYGQDG
                     GQLPPADADALTDFIRAIENPFAVELADLDESKSSGLIQVIGEDVDMEYLREVKDVNI
                     NQDLINNFGKDMKIVYTPLHGTGEMLTRRALAQAGFESVVVVESQAKADPDFSTVKSP
                     NPESQAAFALAEELGREVDADVLVATDPDADRLGVEIRQPDGSYKNLSGNQIGAIIAK
                     YILEAHKTAGTLPENAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDEIYKE
                     YGYFAEKTISVTLSGVDGAAEIKKIMDKFRENGPKQFNNTDIVLLEDFQKQTATKNDG
                     TISNLTTPPSNVLKYTLADDSWIAVRPSGTEPKIKFYIATIGDTLDIAQEKIANIETE
                     INTFVG"
     gene            complement(7875..8444)
                     /locus_tag="VCR92_001366"
     CDS             complement(7875..8444)
                     /locus_tag="VCR92_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEP4268427.1"
                     /translation="MNHRKSADISRIAIFFAIMLVIHFVSSLVFNIWPIPIKPTLVHI
                     PVIIASVLYGPRIGAILGGLMGIISVITNTIILLPTNYLFSPFVDHGTFASLIIAIIP
                     RILIGITPYYCYKLIPNQFGLIVSGIIGSLTNTIFVLSGIFIFFATVFDGNIKALLTA
                     IISSNAIVEMIISAIITFVLIPTLSRLKR"
     gene            complement(8502..9047)
                     /gene="coaC"
                     /locus_tag="VCR92_001367"
     CDS             complement(8502..9047)
                     /gene="coaC"
                     /locus_tag="VCR92_001367"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEP4268428.1"
                     /translation="MTKHITLAVSGSISAYKAADLTSQLTKIGYDVHIIMTQAATQFI
                     TPLTLQVLSKNAIHLDVMDEHDPKVINHIELAKRTDLFIVAPASANTIAHLAYGFADN
                     IVTSVALALPATTPKLIAPAMNTKMYQNPITQENIKRLSTIGFTEIPPKSSLLACGDK
                     GPGALADIDVILATIDTIWKL"
     gene            complement(9040..9732)
                     /gene="coaB"
                     /locus_tag="VCR92_001368"
     CDS             complement(9040..9732)
                     /gene="coaB"
                     /locus_tag="VCR92_001368"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEP4268429.1"
                     /translation="MTMKLIITSGGTTEPIDAVRGITNHSTGQLGKLITERFLQYHHD
                     VTLVTTKTATKPLPNKLLRIIEVETVNDLMAALKDQVPHHDILIHSMAVSDYTPVYMT
                     DLEQVSQADNLNCFLCEHNSEPKISSASDYQVLFLKKTPKVISYVKQWNPNIKLVGFK
                     LLVNVPQEELIKVARASLAKNHADYILANDLVDIQTGMHKALLISNNEVASADTKEAI
                     ADLLYERMTKHD"
     gene            9913..10764
                     /locus_tag="VCR92_001369"
     CDS             9913..10764
                     /locus_tag="VCR92_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HEP4268430.1"
                     /translation="MKGRIVITIRDLASLPIFVYGDGNKKVPGALSPFVWTEVFLKTI
                     NQEPNQLILHIWPMTRTVILGMLDRQLPYFELAKTEIGNNGYVPVTRNIGGLAVVADD
                     GILNFSLVIPDHFSESISISNAYLIMVDVIRESFSDYYQRIEYHEIKNSYCPGNFDLS
                     IAGRKFAGIAQRRIKKGIVVSIYLSVCGDQAARGQLIKDFYEAGTQGEVTKVNYPQID
                     PECMATLSELLETPFTVAEVLERLRLTLRQLGFSLTEKSPDQALLTNFDAVYERMQLE
                     VVRKEGK"
     gene            10761..11960
                     /locus_tag="VCR92_001370"
     CDS             10761..11960
                     /locus_tag="VCR92_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HEP4268431.1"
                     /translation="MKERFSPLFEPLTLPNGSQLDNRFVLSPMVTNSSTKDGYVTQDD
                     VSYALRRAASAPLQITGAAYVDPYGQLFEYGFSVTKDADISGLKELAQAMKAKGAKAV
                     LQLTHAGRFASHALTKYGFVYGPSYMQLRSPQPHEVKPLTGQQIEELIAAYAQATRRA
                     IQAGFDGVEVSSAQRLLIQTFFSTFSNKRTDSYGCQTLFNRSKLTLAVLQAVQQVINQ
                     EAPDGFIFGFRATPEETRGNDIGYSIDEFLQLMDWVLNIAKLDYLAIASWGRHVFRNT
                     VRSPGPYYGRRVNQVVRDYLRNKLPVMATGGMNTPDKAIEALAHADFIGVSTPFVVDP
                     EFAHKIKEGCEESIHLRIRPADLKSLAIPQASFKDIVPLMDYGESLPKESRTLFRSLT
                     HNYKEIK"
     gene            11957..12955
                     /locus_tag="VCR92_001371"
     CDS             11957..12955
                     /locus_tag="VCR92_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEP4268432.1"
                     /translation="MKVSILDYGVIDKEKTPQEALLETRCLAQVADKLGFHRFWVAEH
                     HNIYAFAISSPELLMMHLADHTKQIRIGSGGIMPLHYSSFKIAEWIMTLEALHPNRID
                     LGIGNSLGTTLVQRALSSIHCKDSYSQVVTELYQYLNPDHLSPLPIFVNPRGNTYPQI
                     WTLSNSLETAELAGQLGLGYTFGIFPYIPKDPITEAKRVSAHYRKAFRPSKLLKIPKL
                     ILAVFIVLSDTDEEAEALAKPLDIWMLGQQDFNEFKTYPDVEEARNYHLTEKQREAIA
                     ANRSRMVIGSPHTVKKQLDRLIEACQADELLAIPLVPEFANRQRTLELLADLYVTI"
     gene            12997..13329
                     /locus_tag="VCR92_001372"
     CDS             12997..13329
                     /locus_tag="VCR92_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HEP4268433.1"
                     /translation="MKKIANYLLIEKTDDRYTISMTPELQDDIGTIGYAEFTDNDHLA
                     VDDIILNLEASKTVMSVLSPLAGAVVERNEAATLTPTLLNSEKAEENWIVVLTDVDQA
                     AFDALEDA"
     gene            13322..14134
                     /locus_tag="VCR92_001373"
     CDS             13322..14134
                     /locus_tag="VCR92_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HEP4268434.1"
                     /translation="MPSSFDLLGEMIDLLQTEQLTSSWACPLPNALTKRQDLWRALIN
                     QRPALPLSKDYLNLEDAYLDDWRASFVPVSVKDCQKTNYTSLFLYHGDIRYLAVDAIV
                     NAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAYHL
                     PASYIIHTVGPRITKGRHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGF
                     PKKEAAQIAIKTVLKWQAEHPESKTLTIIFNTFTSEDKALYDTYLQKENNCE"
     gene            14127..15008
                     /locus_tag="VCR92_001374"
     CDS             14127..15008
                     /locus_tag="VCR92_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent deacetylase"
                     /protein_id="HEP4268435.1"
                     /translation="MSNWTTYPQKNLTQAEQLAQLIKEADALVVGIGAGMSAADGFTY
                     IGPRFETAFPDFIAKYQFLDMLQASLFDFEDWQEYWAFQSRFVALNYLDQPVGQSYLD
                     LKEILETKDYHIITTNADNAFWVAGYDPHNIFHIQGEYGLWQCSQHCHQQTYKDDTVI
                     RQMIAEQKNMKVPGQLIPHCPECEAPFEINKRNEEKGMVEDADFHAQKARYEAFLSEH
                     KEGKVLYLEIGVGHTTPQFIKHPFWKRVSENPNALFVTLNHKHYRIPLSIRRQSLELT
                     EHIAQLISATKTIYQKS"
     gene            15055..16074
                     /locus_tag="VCR92_001375"
     CDS             15055..16074
                     /locus_tag="VCR92_001375"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEP4268436.1"
                     /translation="MYLIEPIRNGKRITDGAVALAMQVYVQENLFLDDDILFPYYCDP
                     KVEIGKFQNAVVETNQEYLKEHHIPVVRRDTGGGAVYVDSGAVNICYLINDNGIFGDF
                     KRTYQPAIEALHHLGATEVEMSGRNDLVIDGKKVSGAAMTIANGRVYGGYSLLLDVDF
                     EAMEKALKPNRKKIESKGIRSVRSRVGNIREHLAPQYQGITIEEFKDLMVCQLLQIET
                     ISQAKRYDLTEKDWQQIDALTERKYHNWEWNYGNAPQYRYHRDGRFTGGTVDIHLDIK
                     KGYIAACRIYGDFFGKADIAELEGHLIGTRMEKEDVLATLNAIDLAPYLGAITAEELG
                     DLIFS"
     gene            16202..17872
                     /locus_tag="VCR92_001376"
     CDS             16202..17872
                     /locus_tag="VCR92_001376"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEP4268437.1"
                     /translation="MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEK
                     MKAVEANEPGKLLLVTAINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRR
                     IIWKRVLDLNDRALRQVIVGLGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKR
                     LADIVVAYTYDRKPVYVRDLKVEGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKVPNLPKAPDAIVIVATLRAL
                     KMHGGVAKSDLAAENCEAVRLGFANLKRHVENMRQFKVPVVVAINEFVADTEAEIATL
                     KALCEEIKVPVELASVWANGAEGGLALAKTVVRVIDQEAADYKRLYSDEDTLEEKVIN
                     IVTQIYGGKAVQFGPKAKTQLKQFTEFGWDKLPVCMAKTQYSFSDNPSLLGAPTDFDI
                     TIREFVPKTGAGFIVGLTGDVMTMPGLPKVPAAMAMDVAENGTALGLF"
     gene            17957..19534
                     /gene="cls"
                     /locus_tag="VCR92_001377"
     CDS             17957..19534
                     /gene="cls"
                     /locus_tag="VCR92_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEP4268438.1"
                     /translation="MIIKKKAKVKYLLHKGKHGFLRGIFSRTTIIVLLIILQLVFLFQ
                     SYAWMEQYRVWITILESVFAITIVLYLVNSDMDAISRMTWLILIMIAPLLGSLFLIYT
                     KLDWGYRGLKQRINHLVDLSAPYLSDDDAILEVLKDSTSTTYHLVQYLERSRGNFPIY
                     NNTRVTYFPTGETFFDSLKEQLFLAKKYIFLEFFIIAEGQMWGEILSILEKKVSEGVE
                     VRVLFDGMNELSTLSSDYAKRLEQIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     SFTGGINLADEYINEVERFGHWKDAGLMLEGEATDSFLILFLQMWSITEKELIIDPYL
                     SDHSLKLPSDGYVIPYGDSPLDTDKIGKNVYIDILNHAKEYVYIMTPYLILDSEMEHA
                     LRFASERGVDIRIIMPGVPDKGVPYALAKTYYKALMTSGVKIYEYQPGFVHSKVFISD
                     NTKAVVGTINLDYRSLYHHFECATYLYRVSVIADIVNDFNEAQKQSLLMTSDHLTQRP
                     WYQKLIGLLVRTIAPLL"
     gene            19874..20212
                     /locus_tag="VCR92_001378"
     CDS             19874..20212
                     /locus_tag="VCR92_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268439.1"
                     /translation="MQIIKRDGHVADFDPDKIYQAIIKAARTVYVIDDTWRQNLTHVT
                     KKVVIDLEEAHVERPTINMVQSLVENRLMDAGYITIAEHYISYRLQRDLERNGYGDKI
                     VVHLRFEQIK"
BASE COUNT         6256 a         3464 c         4238 g         6469 t
ORIGIN      
        1 taaccttttt taatgtattt taactgaaaa aggctttcat aattttaaaa aaatgttaaa
       61 ataggtgtat aacaactgat taccaagaga ttattatcat tatcttctaa ggtgtcattg
      121 ttatggtgac aatcaaccat acgctactaa agataggtag cgttcgatca caggttgatc
      181 aagtgattga tacagatatt tataatttta caaatatctg tatcaatcca tgttgaatag
      241 tctatgcttc taaggtgtcg acgttaatgt actgacggga ccgttatagt ctttcttttt
      301 ggagaaacgt cggatgccag tgaactagtt gaagttaaag atgttaattc aaacagtgct
      361 gaagagattg atatcgtttt gaacggtcgt ttacttcaaa gcaaagaaat taccagtcta
      421 tcggagatga tataagtgct aaagttagat cacgttaatt atctatcaag tcgggtgcat
      481 atttcgttaa agtatctaca ggggtttcaa tagatgtagc tattatgaaa ggtgatgtta
      541 aatggggact actgatttag taagttgtgc tgtacaagct agtgagtatg cttatgtccc
      601 ttactctcat tttccagtag gagcagcttt aaaaacaaaa gatggaacga tctatactgg
      661 ctgtaatatt gaaaatgtta gttttggtct gacaaattgt ggagagcgaa cagctatatt
      721 taaagccata tctgatggtc ataaagaatt ggttgaaatt gctatttatg gagaaactat
      781 gcaacctgta tctccttgtg gggcttgtcg tcaggtaatg gcagaatttt ttgctccttc
      841 ttctttagtc actttaattg ctaaaaatgg tcaaactgtt gaaatgactg ttggagattt
      901 actcccctat tcttttacag atttaatata atctgcttta atttctgtta tctagccgtc
      961 ttggctttat atttactttc agcaacttat ttgctagaaa tcttttttag gagggttcat
     1021 attcatgaac aagaaattta ttggtcttgg tttagcgtca gtggctgtgc tgagtttagc
     1081 tgcttgtggt aatcgtggtg cttctaaagg tggggcatca ggaaaaactg atttaaaagt
     1141 tgcaatggtt accgatactg gtggtgtaga tgacaaatca ttcaatcaat cagcatggga
     1201 aggcctgcaa tcttggggta aagaaatggg ccttcaaaaa ggaacaggtt tcgattattt
     1261 tcaatctaca agtgaatctg agtatgcaac taatctcgat acagcagttt caggagggta
     1321 tcaactgatt tatggtatcg gctttgcatt gaaagatgct attgctaaag cagctggaga
     1381 taatgaagga gttaagtttg ttattatcga tgatattatc gaaggaaaag ataatgtagc
     1441 cagtgttacc tttgctgacc atgaagctgc ttatcttgca ggaattgcag ctgcaaaaac
     1501 aacaaaaaca aaaacagttg gtttcgtggg cggtatggaa ggaactgtca taactcgatt
     1561 tgaaaaaggt tttgaagcag gagttaagtc tgttgacgat acaatccaag ttaaagttga
     1621 ttatgctgga tcatttggtg acgctgcaaa aggaaaaaca atcgcagcag ctcagtatgc
     1681 agcaggtgct gatgttattt accaggcagc aggaggcact ggagcaggtg tatttaatga
     1741 agcaaaagct attaatgaaa aacgtagtga agctgataaa gtttgggtta ttggtgttga
     1801 ccgtgatcaa aaagacgaag gaaaatacac ttctaaagat ggcaaagaag caaactttgt
     1861 acttgcatca tcaatcaaag aagttggtaa agctgttcag ttaatcaaca agcaagtagc
     1921 agataaaaaa ttccctggag gaaaaacaac tgtctatggt ctaaaagatg gcggtgttga
     1981 aatcgcaact acaaatgttt caaaagaagc tgttaaagct attaaagaag cgaaagcaaa
     2041 aattaaatct ggtgacatta aagttcctga aaaatagtgt ttaagaacaa gaagcgcgac
     2101 ctttgtcggt cgctcttttt aaactgagat aatttttatc tcagtaaagt ttgtgatagg
     2161 tgatagatca taggctttac tgaaataaaa gattgcattg aaaggaaatg atcctatgac
     2221 acagcatgtc attgaaatga gagaaatcac gaaaaaattt ggtgattttg ttgcaaatga
     2281 ccacattaac ttaaatgtca gaaaaggtga gattcatgcc ttattgggtg aaaatggggc
     2341 aggtaaatca actttgatga atatgctagc tggtctctta gagcctacta gtggagaaat
     2401 tgtcattaat gacaagccag ttcaaattga ttcgccatct aaatcagcta agcttggtat
     2461 cggaatggta catcaacatt tcatgttagt agaagccttc acggttgctg agaatattat
     2521 tttaggaaat gaagtagtaa aaaatgggtg cttagatctt aaccaagcat cgaaagatat
     2581 taaggtacta tccgaaaaat atggccttgc aatcaatcca tcagctaaag tttctgatat
     2641 ttcagtagga gcacaacaac gtgttgagat tttgaaaacc ttgtatcgtg gtgcagatat
     2701 tcttatcttt gatgagccaa ctgccgtttt aacacctgca gaaattaaag aattgatgac
     2761 tatcatgaag aatctcgtga aagaaggaaa atcaattatt ttaattaccc ataaactgga
     2821 cgagattcgt gctgtcgccg agcgtgtcac agttattcgt cgtggtaaga gtatcgaaac
     2881 agttgatgtg gcaggagcaa cttcacaaga tttagctgag atgatggtgg gacgctcggt
     2941 ttcctttaca actagcaaaa aagctgctga accaaaagat gtggtcttat ccatcaaaaa
     3001 tcttgaagta gatgaaaata gagggattcc agcagttaag gggctatctc tagatgtccg
     3061 agctggtgaa attgtaggga ttgctggaat tgacggaaat ggtcaatctg agttaattca
     3121 agctattaca ggtttacgta aagtcaaatc tggaagtatt atgattaaaa acaaagaagt
     3181 cactcatttg tcttcacgca aaattactga gttatcagtg ggtcacgtgc cagaagatcg
     3241 tcatcgagat ggtttgatac tagatctttc tttagctgaa aatacagcct tacaaaccta
     3301 ttacaaacaa cctctaagtc aaaatggaat cttaaattat actaaaatta atgactatgc
     3361 tcgtcaatta atgaaagaat ttgatgttcg cggagccaat gagctagtac cagctagagg
     3421 attttctggt ggtaaccaac aaaaggccat tattgctcgt gaagtggacc gtgatccaga
     3481 tttacttatt gttagccaac caacacgtgg tcttgacgta ggagctattg aatatatcca
     3541 taagcgtttg attaaagaac gtgataaagg taaagctgtc ctcgttgtta gttttgaact
     3601 tgatgaaata ttgaatttat ctgatcgaat tgctgttgtt catgatggta aaattcaagg
     3661 tatcgtattg ccagaaaata ccaataaaca agaattgggt attttaatgg caggtggttc
     3721 aattcataag gaggaaggtc atgtctaaaa atgcgcaaaa aattgctgta ccattgattt
     3781 ctgtcttgct aggattttta cttggcgcta ttattatggt tatctttggt tatgatccta
     3841 tctgggggta tgaaggttta ttccaaattg cctttggtag tgttaaaaat attggagaaa
     3901 tattccgttc aatggggcca ttgattttaa tagcgcttgg ctttactgtt gctagccgtg
     3961 caggcttctt taacgttggt ttgtctggac aggctttagc tggatggatt tcagcaggtt
     4021 ggtttgcact cttaaatcca gatatgcctc gtccattatt gattcttatg acagctctta
     4081 tcggaatgat tgctggtggt attgctggag ctattccagg gatacttcgt gcttatcttg
     4141 gtacaagtga agttatcgtt acgattatga tgaactacat cattttatat gtcggaaatg
     4201 ctattgttca acgtggttat cctgagagtg tcaaacaaag tattgattca actattcaag
     4261 ttagtgataa tgctagttat caaacgcatt ggttatcagc cctaactaat aactctcgta
     4321 ttaatattgg tattttcttt gccattattg ccattgccct aatctggttc ttgcttaaca
     4381 aaactacttt aggttttgag attcgttcag ttggtctcaa cccacatgct tcagaatacg
     4441 cagggatgtc atcaaaacgt actatcattt tatcaatgat tatctctgga gctcttgcag
     4501 gtcttggagg agtagttgaa ggtctaggaa cctttgaaaa tgtttttgta caaggatctt
     4561 ctttagcagt tggttttgac ggtatggcag ttagcttatt agcagcaaat tcaccgcttg
     4621 gaatattttt ctcatcattc ctatttggtg tcttaaatat tggtgctcca ggaatgaata
     4681 ttgcaggcat tccaccagaa cttgttaaag tagtaactgc atcaatcatt ttctttgttg
     4741 gttcacatta cctcattgaa cgttacatta ttcgccctaa aaaattagtg aaaggtggta
     4801 aataagatga gtttagtaac aatttttgcc ttattggtgt catctatgct tatttatgca
     4861 acaccactca ttttcacaag tattggagga actttctcag agcgctcagg cgttgttaat
     4921 gttggtttag aaggtatcat ggtcatggga gcgttctctg ggattgtttt caacttagag
     4981 tttgctgaaa catttggaaa agcaacgcct tggatagccg ttttagtcgg tggtattgtt
     5041 ggtttgattt tttctttgat tcacgctgta gcaaccatca actttcgagc tgaccacatt
     5101 gtcagtggta cagtgttgaa cttgttagca ccttcttttg ctgtcttctt ggttaaagct
     5161 atgtacggta agggacaaac agacaacatt caacaatctt ttgggaagtt tgatttccca
     5221 ggtttatcac aaattcctgt gattggtgat attttcttta aaaatactag ccttattggt
     5281 tacttcgcca ttgctttttc gttctttgct tggtttttgc tttataaaac caggtttggt
     5341 ctgcgtttac gatcagttgg ggaacaccct caggcagctg acacacttgg tattaacgtc
     5401 tatttgatga aatactatgg tgtgatgatc tcaggttttc ttggtggaat aggtggagct
     5461 gtttatgctc agtcaatctc cgttaacttt gctgtaacaa ctatcttagg tcctggattt
     5521 attgctttgg cagctatgat ctttggtaaa tggaatccag ttggcgccat gctatctagt
     5581 cttttctttg gcttatcgca aagtttagcc gttattggtg ctcaattacc attactagaa
     5641 aagattccaa cggtttactt acagattgca ccttatatgg taacgattat tattttagct
     5701 gctttctttg gtcaagcagt tgcaccaaaa gctgatggaa tcaactatat taaatctaaa
     5761 taacgttata ttagtagtaa gcctcttagt gaggtttaac agcactccta aagcaagata
     5821 gttaggtcta gctttaaggg tgcttttttg ggacttaccg caagcgtttg gattgccagt
     5881 caccatcaca atagaagcaa gaatagacta aaaagaacta agtcagcggc ttagttcttt
     5941 ttgcttgtct ttcgttttta ctgatagctc ttaagttgtt ttagccaaca aaggtattga
     6001 tttctgtttc aatgttagca attttttctt gagcgatgtc aagagtatca cctattgtgg
     6061 caatatagaa cttgattttt ggttcagttc ctgaagggcg aactgcaatc catgaatcat
     6121 cagctaacgt gtacttcaaa acattacttg gaggagttgt taagttagat attgttccat
     6181 catttttagt agcggtttgt ttttggaaat cttctaataa tacaatatca gtattgttaa
     6241 attgttttgg accattttca cggaatttgt ccataatctt cttaatttca gcagctccat
     6301 ccacacctga aagtgttact gaaatcgttt tttcagcaaa atagccatat tctttgtaaa
     6361 tttcatcaat accatctgca agtgttaaac cacgcgaacg gtaataagct gcgatctcag
     6421 caaccaaaag aactgcttga atagcatctt tatcacggac aaatggttta ataagatatc
     6481 cgaagctttc ttcaaaacca aacatatagg tgtggttatg tttttcttca aactcttgaa
     6541 ttttctcagc gatgaatttg aatccagtta aaacgttaaa cattgtagcg ccataacttt
     6601 cggcaatttt tgttactaat tctgttgata cgattgattt agcgagagca gcattttctg
     6661 gaagtgttcc tgctgtttta tgagcttcca ggatgtattt cgcaataatc gctccaattt
     6721 gatttccaga aaggttttta taagaaccat ctggttggcg aatttcaacg cctaggcggt
     6781 ctgcatcagg atcagtagct actaagacat ctgcatcaac ttctcgtccg agttcttcag
     6841 caagagcaaa ggcagcttgg ctttcagggt taggcgattt aacagtagaa aagtctggat
     6901 ctgccttagc ttgtgattcg actacaacaa cagattcaaa accggcttga gcaagggcac
     6961 ggcgtgtcaa catctcacca gttccgtgga gaggagtata gacaattttc atgtcttttc
     7021 caaagttatt gattaaatct tgattgatat taacatcttt aacctctcta agatattcca
     7081 tatcaacatc ttcaccgata acttgaataa gacctgatga tttgctttca tctaaatcag
     7141 caagttcaac tgcaaatgga ttttcaatag cacggataaa gtctgttagt gcatcagcat
     7201 cagctggtgg tagttgacct ccgtcttgtc catagacttt ataaccattg aaaggtgctg
     7261 gattgtggct tgcagtaacc ataataccag cataggcatt taaatggcga acagcaaaag
     7321 agagttctgg tgttggacga agagcttcaa atacgtaaga tttaatccca tgctgtgcca
     7381 agacctgtgc agactcaaaa gcaaattctg gagagaagtg gcgcgaatca taagcgatgg
     7441 ctacaccatg ttttttagct tcctctccct tagtttcgat taattttgct aatccttcgg
     7501 ttgcttgacg gacaacataa atattaatac gatttgtacc agcaccaata taaccacgca
     7561 taccagcagt accaaattct aagtttgtgt aaaaagcatc ttcttttgtt ttttcatcca
     7621 ttgatagtaa ttcttgacga agatagtcag gaagctgctc aaaatctaac catttttgaa
     7681 aattttctgt gtaagtcatt gaaatactcc ttcaatattt ataaacgctt tcattatatc
     7741 attttgaagg aaaaaaaaca ctaattattt gcagctgttt acaaaacttt ttccatattt
     7801 tcaagtagct aatgtaagaa agttaaaata accaagtttt taaaagagaa aaactcggtt
     7861 attgtgaaag ctaattacct ttttagtctt gatagtgttg gaataagtac aaaggtaata
     7921 atagctgaga tgatcatctc aacaatagcg tttgatgaga tgatggctgt tagtagtgct
     7981 ttaatatttc catcaaaaac tgtcgcgaaa aaaataaata tcccagataa tacaaatata
     8041 gtatttgtta gagaaccaat gataccggat actattaaac caaactgatt aggaatcaat
     8101 ttatagcaat aataaggggt aataccaatc aaaatacgtg ggataatagc aattattaaa
     8161 gaagcgaaag ttccatgatc gacaaaaggt gaaaagagat aatttgtagg cagtagaatg
     8221 atggtatttg taatgacact tataatcccc attaatcctc ctaaaatagc acctatcctt
     8281 gggccatata agacagaagc aataataact gggatatgga caagcgttgg tttgattgga
     8341 ataggccaaa tattaaagac aagactgctc acaaaatgaa tgactaacat gatggcaaaa
     8401 aagatagcaa tacgagaaat atctgctgat ttacggtgat tcattttact ctccaaaaaa
     8461 tataatactt aattctaaaa aggtgatcag aaaaacgact gttaaagttt ccaaatcgta
     8521 tcaatagtag ctaagataac atcaatatca gccaaagcac caggtccttt atctccacag
     8581 gctaataagc tagattttgg aggaatttct gtaaacccta ttgtcgataa gcgtttaata
     8641 ttttcttggg taatagggtt ttgatacatt ttggtattca tggctggggc tattaatttt
     8701 ggtgtggtag ctggtagggc aagagcaaca cttgttacaa tattatcagc gaatccatat
     8761 gctagatgag caatagtatt agcagaggca ggtgcaacaa taaataaatc tgtgcgtttt
     8821 gctaattcga tatggttgat aacttttggg tcatgctcat ccataacatc taaatgaata
     8881 gcattttttg ataacacttg cagggttaat ggtgtaataa attgtgtagc agcctgagtc
     8941 attatgatgt gaacatcata gccaatttta gttaattgac tcgtaagatc tgctgcttta
     9001 taggcagata tactaccaga aacagctaag gtaatatgtt tagtcatgtt tggtcatcct
     9061 ttcatataat aagtcagcaa ttgcctcttt ggtatctgca gatgcaactt cgttattgga
     9121 tatcaaaaga gccttgtgca tacctgtttg gatatcaact aaatcattgg cgagaatata
     9181 atcagcatgg tttttagcta gacttgctct ggctacttta attaactctt cttgaggcac
     9241 attaactaga agtttaaagc cgactagttt aatattagga ttccactgtt taacataaga
     9301 gataactttg ggtgtttttt tcaaaaaaag aacctgataa tcagatgcag atgagatttt
     9361 cggctcactg ttatgttcac atagaaaaca attaaggtta tcagcttgag agacttgttc
     9421 caaatcagtc atgtagactg gagtatagtc agaaacagcc atactatgaa ttagaatgtc
     9481 atggtgagga acctgatctt tgagggcagc cattaagtcg ttaactgttt ccacttcaat
     9541 aatccttagg agcttatttg gcaggggttt agtggctgtt ttagtagtga ctagggtaac
     9601 gtcatgatga tattgtaaaa atcgctctgt gattaatttt ccaagttgcc cagttgagtg
     9661 attagtgata cctcgtactg catctatagg ttcagttgtt ccacctgatg ttattattaa
     9721 tttcatagtc atattttatc aaaaaaggag ctgatagtaa acggaagata atgacgccag
     9781 acattgtctt gcgtttgtat taatatggaa tagtaataga tttctagtaa ttaaaacgaa
     9841 gttctggaaa gcaagacact atagtagcta aaatctaaat tttaaggtaa aatagagcaa
     9901 gcggtttcaa gtgtgaaagg aagaattgtg ataactatta gagatttagc gtcactgccg
     9961 atttttgttt acggtgatgg aaataaaaaa gttccaggag ctttgagtcc ttttgtgtgg
    10021 acagaggtgt ttttaaaaac tatcaatcaa gaacctaatc aactgatctt acatatttgg
    10081 ccgatgacaa gaacagttat attagggatg ttagatagac agcttcccta ctttgagctg
    10141 gctaaaacag agattggcaa taatggttat gttcctgtta ctcgtaatat tggcggtttg
    10201 gctgttgtcg ctgatgatgg gattttgaat ttttcgcttg ttattccaga ccatttttcg
    10261 gaatctatca gtattagtaa tgcttattta ataatggttg atgtcattag agagagtttt
    10321 tcggattatt atcagcgtat tgaatatcac gaaattaaaa attcttattg ccctggtaat
    10381 tttgatctta gtattgcagg ccgcaagttt gcaggtatcg cccagcgtcg tatcaaaaag
    10441 ggaattgttg tgtctattta cttgagcgtt tgtggggatc aagcagcgcg tggtcaactc
    10501 atcaaggatt tttatgaggc cggaacacaa ggagaagtta ccaaggttaa ttaccctcaa
    10561 attgatccag aatgcatggc aactctttca gaactccttg agacgccttt tacagtggca
    10621 gaagtccttg aacgtcttcg attgaccttg cgacagcttg gcttttccct cacggaaaaa
    10681 agtccagatc aagccttact gactaatttt gatgctgtct atgaacggat gcagctagaa
    10741 gtcgtcagaa aggaaggcaa atgaaagaaa gatttagtcc tttatttgag cctttgactt
    10801 tgccaaatgg gagtcaattg gataatcgct ttgttttgtc tcctatggtg accaactcat
    10861 ccacaaaaga cggttatgtc acccaagatg atgtatccta tgctttgaga cgagcagctt
    10921 ctgcccctct acaaattaca ggagcggcct atgtggatcc ttatggtcaa ttgtttgaat
    10981 atggttttag tgttacaaaa gatgccgata tttctggctt gaaagagcta gctcaagcga
    11041 tgaaggcaaa gggagctaaa gctgtcttac aactgaccca cgctggccgg tttgctagcc
    11101 atgccttgac taaatatggc tttgtctatg ggcctagtta catgcagttg agatctcccc
    11161 aacctcatga agtcaaacct ttaacaggtc agcaaataga ggaattgatt gcagcttacg
    11221 ctcaggctac tcggcgggca attcaagcag gctttgatgg cgtggaagta tcttcggcgc
    11281 agcgcttatt gattcaaacg ttcttttcga ctttttcgaa caagaggaca gatagttatg
    11341 gttgtcaaac actttttaat cgctctaagt taactttagc tgttttgcaa gctgttcaac
    11401 aggtgattaa tcaagaagct cctgatgggt ttatttttgg atttcgtgct acaccagaag
    11461 aaactagggg aaatgatatt ggttatagta ttgacgagtt tttgcagttg atggattggg
    11521 tacttaatat tgcaaaactt gattatttag cgatagcaag ttggggccgt catgtatttc
    11581 gaaatactgt tcgttctcct ggcccttatt atggaaggcg agttaatcag gtagttagag
    11641 attatttaag aaataagcta cctgttatgg ctacaggggg aatgaacaca cctgacaaag
    11701 ctattgaagc actagctcat gctgatttta ttggagtatc tacacctttt gtcgtggatc
    11761 cagaatttgc tcataaaatc aaagaagggt gtgaagagag tattcattta aggattcgac
    11821 ctgctgattt gaaaagttta gcgattcctc aggcttcttt caaagatatt gtacctttga
    11881 tggactacgg ggaatcattg cctaaagaat caagaacttt atttcgtagt cttactcaca
    11941 attataagga gattaaatga aagtcagtat tcttgattat ggggtgattg ataaagaaaa
    12001 aacaccccaa gaagctttat tagaaacgcg ctgcttagca caagtagccg acaaacttgg
    12061 ttttcatcgt ttttgggtag cagagcatca taatatttat gcctttgcaa taagcagtcc
    12121 agagctgttg atgatgcatt tagcagatca taccaaacag attcggatag gttcaggagg
    12181 tattatgcct ctacattata gtagctttaa gattgcagaa tggataatga ctttagaggc
    12241 cttgcaccct aatcggattg atttaggtat tggcaactct ttaggaacta cgttagttca
    12301 aagagctcta tcaagtatcc attgcaaaga cagctatagt caggttgtca cagaattata
    12361 ccagtatctt aatcctgatc atttgtcacc actaccgatt tttgttaacc ctaggggtaa
    12421 tacttaccct cagatttgga cgctaagcaa tagtttggag acagcagaac tggctggtca
    12481 attaggttta ggctatacct ttggtatttt cccctatata ccaaaagatc ctataacaga
    12541 agctaaaaga gtatcggcac attatagaaa ggcttttagg ccttcaaagc tattaaaaat
    12601 ccccaagtta atattagcag tttttattgt cctttctgat accgacgagg aagcagaagc
    12661 tttggctaaa ccgttggaca tttggatgct tggtcagcaa gattttaatg aatttaagac
    12721 ctaccctgat gttgaggagg ctagaaacta tcacttaaca gagaaacaaa gagaagccat
    12781 tgcagcaaat cgtagtcgca tggttattgg atcacctcac acagtcaaga aacaattgga
    12841 taggctgata gaagcttgtc aagctgacga attattagcc atccccttag ttcctgaatt
    12901 tgccaataga caacgaacct tagagctgct agcagactta tacgtgacca tttaacctta
    12961 ccaaaaacaa ttccctaaac tgaaaggaaa gaaacaatga aaaaaattgc aaattactta
    13021 ttaattgaga aaacagatga ccgctatacc attagcatga caccagaatt acaagacgat
    13081 attggtacta ttggttacgc tgaatttacg gataacgacc accttgccgt tgatgacatt
    13141 atcttaaatc tagaggcttc taagaccgtc atgtctgtct tgtcaccatt ggctggggca
    13201 gttgttgagc gcaatgaggc agccacacta acaccaaccc ttttgaattc agaaaaagct
    13261 gaggaaaatt ggattgttgt gctaacagat gttgatcaag cagcttttga tgccttagaa
    13321 gatgcctagt tcatttgatt tattagggga aatgattgat ctgttgcaaa cagagcagct
    13381 tactagttct tgggcctgtc ccttgcctaa tgctttaaca aagcgacaag acttgtggcg
    13441 ggcgctcatt aaccagcgcc ctgctttgcc tttatcaaaa gattacttga atctggaaga
    13501 tgcttatcta gatgattggc gtgcttcttt tgttcctgta tcagtcaagg actgccaaaa
    13561 aactaattat accagtcttt ttctttacca tggggatatt aggtaccttg ctgtggatgc
    13621 tattgtcaat gctgctaata gtgagttatt gggatgtttt atccctaacc atggctgtat
    13681 tgataatgcg attcatacgt ttgccggaag tcgtttacgc ttagcttgtc aggcaatcat
    13741 gactgaacaa ggccgtaagg aagccattgg ccaagcaaag cttaccagtg cttatcatct
    13801 accagcctct tatattattc ataccgtagg gccaagaatt accaaaggac gacacgtttc
    13861 tccgattcga gctgatttgt tagcacgttg ttatcgttct agtcttgatt tggcggttaa
    13921 agcaggattg actagcctag ctttttgctc tatttcaaca ggagaatttg gctttcctaa
    13981 aaaagaagcc gctcagattg ccattaagac agttttaaaa tggcaagcag aacatccaga
    14041 atctaagact ttaactatca tttttaatac ctttacatca gaagacaagg ccttatacga
    14101 cacttatttg caaaaggaga ataactgtga gtaattggac aacctatcct cagaaaaatc
    14161 tcacccaggc agaacaactg gcccaattaa tcaaagaagc agatgcactt gtagttggta
    14221 ttggagctgg catgtctgca gctgatggtt ttacttatat cgggccgcgt tttgagacgg
    14281 cattcccaga ttttattgct aagtatcagt ttttggatat gctgcaagct agcctttttg
    14341 attttgaaga ttggcaagaa tattgggctt ttcaaagtcg ctttgtcgct ttgaattatc
    14401 ttgatcagcc cgtaggccag tcttatcttg atttaaaaga gattttggaa accaaagact
    14461 atcatattat tactactaat gctgataatg ctttttgggt ggctggttat gatcctcata
    14521 acatttttca cattcaagga gaatatggtt tgtggcaatg tagccagcac tgccatcagc
    14581 aaacttataa ggacgatacg gtcatccgtc aaatgatcgc agagcaaaaa aacatgaaag
    14641 tcccaggtca actgattcct cattgccctg aatgtgaggc gccttttgaa atcaataagc
    14701 gtaatgaaga aaaaggaatg gttgaagatg ctgactttca tgcccaaaaa gcacgttatg
    14761 aggctttttt atcagaacat aaagagggta aagtgcttta tctagaaatt ggtgtgggac
    14821 atacgacgcc tcagtttatc aaacacccct tttggaaacg tgtctcagaa aaccctaatg
    14881 ccttattcgt taccttgaat cacaaacatt accgcatccc tctgtcaata aggcgacaaa
    14941 gcctagaact gacagaacac attgcacaat tgattagcgc cacaaaaacc atttaccaaa
    15001 aatcgtaacc aaagccaata gacggttaat taagagatat agaaggagac taacatgtac
    15061 cttattgaac cgattcgtaa cggtaaacgt atcaccgatg gagctgttgc tctagccatg
    15121 caagtttatg ttcaagaaaa tctattttta gatgatgata ttttatttcc ctactattgt
    15181 gatcccaaag ttgaaattgg aaaattccag aatgcggttg tagaaactaa tcaagagtat
    15241 ttaaaagagc atcatatccc tgttgttcgc cgagatactg gcggtggtgc cgtttatgta
    15301 gattctggtg ctgttaatat ttgctacttg attaatgata atggtatttt tggtgatttt
    15361 aaaagaacct atcagcccgc tattgaagcc cttcatcatt tgggagcaac agaggttgaa
    15421 atgtctggac ggaatgactt ggttattgat gggaaaaagg tatctggcgc tgcgatgact
    15481 attgctaatg gccgtgttta tggggggtat tcccttttgc tagatgtgga ctttgaagcc
    15541 atggaaaaag cattaaaacc taatcgcaaa aaaattgaat caaaaggcat caggtcagtt
    15601 cgtagtcgcg ttggaaacat cagagaacat ttagcaccac aataccaagg tattacgatt
    15661 gaagagttca aagatttaat ggtttgccaa ttgttacaga ttgagacgat tagccaagct
    15721 aagcgttatg atttaacgga aaaagactgg caacaaattg atgctttaac agagcgtaaa
    15781 tatcacaatt gggaatggaa ttatggcaac gcgcctcaat accgttacca tagagatggc
    15841 cgttttaccg gtggaacagt agatattcat ttagatatta aaaaaggcta tattgcagct
    15901 tgtcgcattt acggagattt ttttggcaag gcagacattg cagaacttga aggtcacttg
    15961 ataggaacac gaatggaaaa agaggatgtc ttagctaccc tcaatgcaat tgatttagcc
    16021 ccttatttag gtgcgattac agcagaagaa ttaggagatt tgatattttc ttgataaaaa
    16081 agatacctca gaccggtaaa gtgcgattaa aaacgaacaa taattgtttt aattcaaata
    16141 aatgtatgta tgatatgaat tgtgatataa tgacgtcatt acgtaaaatt gaggagtcat
    16201 catgaaatca gatatcgaaa ttgcccaaag tgtcgcccta caaccaatca ctgacattgt
    16261 taaaaaggtt ggaatagacg gcgatgacat tgagctttat ggcaaatata aggctaaatt
    16321 gtcttttgag aaaatgaaag ctgtcgaagc taatgagcct ggaaaattac tcttggtaac
    16381 tgctattaac cctactccag cgggagaagg aaaatcaacc atgtctattg gactggcaga
    16441 tgccttaaat caaatgggaa aaaaaaccat gcttgcctta cgtgaaccct cccttggtcc
    16501 tgttatgggg attaaaggcg gggcagcagg tggtggttat gcccaagtat tgcctatgga
    16561 agacattaat cttcacttta ctggtgacat gcatgccatt acaaccgcta ataatgcatt
    16621 atctgctttg attgacaatc atttgcagca aggaaacgat ttaggaattg atcctcgccg
    16681 cattatttgg aagcgcgtgt tggaccttaa tgatcgtgct cttcgtcagg taattgttgg
    16741 cttaggcagt ccagtgaatg gtgtgccacg cgaagatggg tttgatatca cagtagcttc
    16801 tgaaatcatg gcaattttat gtttggcaac tgacttgaaa gatctaaaga aacgtcttgc
    16861 tgatatcgtc gtggcttata cctatgatcg taagcctgtc tatgtgcgtg acttgaaggt
    16921 tgaaggagca ttgacattaa ttctaaaaga tgctatcaag ccaaacttgg tgcagactat
    16981 ttatggaaca ccagctctta ttcatggggg gccatttgct aatattgctc atggttgtaa
    17041 ttctgtcctt gctacctcaa cagctttgcg attagcagat tacactgtta ccgaagcagg
    17101 attcggggcc gacctaggag ctgaaaaatt cctaaatatc aaagtaccta atcttcctaa
    17161 agcaccagat gctatcgtca ttgttgcaac cttgcgcgcc cttaaaatgc atggaggtgt
    17221 cgccaaatca gatttagccg ctgaaaattg tgaggctgtt cgcttaggat ttgccaactt
    17281 aaaacgtcac gtggaaaaca tgcgccaatt caaagttcca gttgtggtgg ctatcaatga
    17341 atttgtagca gataccgagg ctgaaattgc taccttaaaa gcgctttgtg aagagattaa
    17401 ggttccagta gaattagcca gtgtttgggc aaatggagct gagggaggct tagcattagc
    17461 taaaacagtg gttcgtgtga ttgatcaaga agctgctgac tacaaacgtc tctattcaga
    17521 tgaggatact ttggaagaaa aagtgatcaa tatcgttacc cagatttatg gtggcaaagc
    17581 tgttcaattt ggccccaagg ccaaaacaca attgaagcag ttcacagaat tcggttggga
    17641 taaattgcct gtttgtatgg ctaagaccca atacagtttt tcagataacc catccttgct
    17701 tggagcgcca accgattttg atattaccat tcgtgaattt gttcctaaaa caggggcagg
    17761 ttttattgtt ggtttaacag gtgatgtgat gaccatgcct ggtttgccta aagttccagc
    17821 tgccatggca atggacgtag cagaaaatgg cacagccctc ggtctctttt aggaaaaatt
    17881 gctcgaataa ttcgagcaag cgctcctttc ttcccgcttt actgtgatat aataaggtaa
    17941 ctgagatttt ggagggatga ttatcaaaaa gaaagcaaaa gtaaaatatt tgctccataa
    18001 agggaaacat ggatttttaa gaggaatttt tagtagaaca acaatcattg tattattaat
    18061 tattttgcaa ttagttttct tatttcaatc ttatgcctgg atggagcagt accgtgtttg
    18121 gataacgatt cttgaaagtg tctttgctat tactattgtt ttatatttag ttaatagtga
    18181 tatggatgct atttcaagaa tgacgtggtt aattttgatt atgattgctc cattactagg
    18241 gtcactgttt ttaatttata caaaattgga ttggggttac agagggctaa aacaaagaat
    18301 aaatcatctt gtagatctgt ctgcacctta ccttagcgat gatgacgcta tattagaggt
    18361 attaaaggat agcacatcaa ccacatatca tttagtacag tacttagaaa gaagtcgtgg
    18421 caactttccg atttataata atacaagggt aacttacttc ccaacaggtg aaactttttt
    18481 tgatagttta aaagaacagt tattcttagc taaaaagtac atttttcttg aattttttat
    18541 tattgcagaa ggccaaatgt ggggagaaat ccttagtatt ctagaaaaaa aagtcagtga
    18601 aggtgtagaa gttagggtgt tgtttgatgg catgaacgaa ctatcaacgc tatcatcaga
    18661 ttacgccaag agattagaac aaatagggat taaagctaaa tcatttttac cgatttcacc
    18721 ctttatctct acctattaca attatcgaga tcaccgaaaa attgtcgtta ttgatgggga
    18781 ggtatcattc actggaggta ttaatctagc agatgagtac attaatgaag tagagcgttt
    18841 tggccactgg aaagatgctg gtttaatgct tgagggtgaa gcaacagaca gctttttaat
    18901 tttgttttta caaatgtggt ctatcacaga aaaagaactg attattgatc cttatctttc
    18961 agatcattct ttaaaacttc cttcagatgg ctatgttatt ccctacggtg attccccgct
    19021 tgatactgat aaaataggta aaaatgttta tatagacatt ttaaatcatg ctaaagagta
    19081 cgtttatatc atgacacctt accttatttt agatagcgag atggaacacg ctttacgatt
    19141 tgcatcagaa cgtggagtag atatccgaat tattatgcca ggagtgccag ataagggggt
    19201 accatatgcc ttagctaaaa cctattataa agctttgatg acttctggag taaaaattta
    19261 cgagtatcaa ccagggttcg ttcattcaaa ggtatttatc tctgataata caaaagcagt
    19321 tgtcggaaca attaacttag actatcgtag cctttatcat cattttgaat gcgcgactta
    19381 tttatatcgt gtgtcagtta ttgctgatat tgtgaatgac tttaatgaag ctcaaaagca
    19441 atcactattg atgacatcag atcatttgac gcaacgtcct tggtatcaaa aattgatagg
    19501 attattagta cgaacaattg cccctctctt gtaattttcg taaaatatgt tataatatct
    19561 gtatgcgatg agtcgattgt gactgcaaag tcacttttgc gcaggggagg tcattaaggc
    19621 gggaagccga ctttgataat ctgtgtgaac cattttatca caatcttatt tattaagaat
    19681 gccccttgga ttgagatatt ctcaatcctt tttttaattt tattatctta gttaaaattc
    19741 agaatgtatc agtgattact gtgtttcaaa ataagaaagt agtttttcgg gtatgagtgc
    19801 tatgacttga caaatgctaa taacatttgc ataatgtaag tagagatgaa aacttatgaa
    19861 aagagatgat cttatgcaaa ttattaagcg tgatggccac gttgctgatt ttgatccaga
    19921 taaaatttat caagcaatta ttaaagcagc aaggacggtc tatgttattg atgacacgtg
    19981 gcgacaaaac ttaacacatg tcactaaaaa agtagttatt gatttagaag aagcacatgt
    20041 agaacgtcct actatcaata tggtccaatc ccttgtggag aatcgtttga tggatgctgg
    20101 atatattacc attgcagaac attacatttc ttatcgtctt cagcgagatt tagagcgcaa
    20161 tggctatggt gataagattg tggttcactt gcgttttgaa caaataaaat aaaaacgctt
    20221 ctaatggcat tttagtgtct ttgaggggat aaggtttaaa tacctaacag ataaaaatct
    20281 gttaggtatt tttttgctac tattaggtgt attctatatc acatagaact taagcattca
    20341 agctttaatt taactttctg tttatttttt gctacatttt gggaaactcc cctcctttct
    20401 tagttgaggt gaataaactt ttatttg
//
LOCUS       DATWEK010000031        18051 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.031, whole genome shotgun sequence.
ACCESSION   DATWEK010000031 DATWEK010000000
VERSION     DATWEK010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18051
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.031"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(256..633)
                     /locus_tag="VCR92_001379"
     CDS             complement(256..633)
                     /locus_tag="VCR92_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEP4268440.1"
                     /translation="MLIYPATFTQDTDYIMVTFPDVPEAITQGEDFQEAYEMAVEVLG
                     FALEDYTDYPKASAVSDLKEQYPDSDIALIGIDMVAYMKKYHSKKVRKNVTIPEWLND
                     AAEDKNLNFSQVLTEALELKLQA"
     gene            complement(685..870)
                     /locus_tag="VCR92_001380"
     CDS             complement(685..870)
                     /locus_tag="VCR92_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEP4268441.1"
                     /translation="MPMTPKQMIKLLKKNGFYEVSQNGSHKKFRDNNGHQTIVPMHNK
                     DLGKGLEDTILKQAGLK"
     gene            933..1400
                     /locus_tag="VCR92_001381"
     CDS             933..1400
                     /locus_tag="VCR92_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEP4268442.1"
                     /translation="MRIKYTKGGDGKLSKLTLKQKRFADEYIISGNAMESAIKAGYSH
                     NYSKAQSHKLLENVGIKEYLDERFEKMDSKTIADQKEVLQYLSSVMRGEQQEKTLISI
                     GELGQEIVDIDVGAKDRLKAAELLGKRYRLFTDKIEAEVQGTVVFVNEDDIPD"
     gene            1378..2685
                     /locus_tag="VCR92_001382"
     CDS             1378..2685
                     /locus_tag="VCR92_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEP4268443.1"
                     /translation="MKTTYQTKPKLEIKVDLPKTIGIGYGAFWRSKNFYRVVKGSRGS
                     KKSKTTALNFIVRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNQLKVTHLFKFNES
                     LPEITVKATGQKILFRGLDDELKITSITVDVGLLCWAWFEEAYQIETEDKFSTVVESI
                     RGSLDAPDFFKQITVTFNPWSERHWLKRVFFDEETKRADTFSGTTTFRVNEWLDDVDK
                     RRYEDLYKTNPRRARIVCDGEWGVAEGLVFDNFEVVDFDVEKTIQRVKETSAGMDFGF
                     TQDPTTLICVAVDLVNKELWLYNEHYQKAMLTDHIVKMIRDKNMHKSYIAADSAEKRL
                     IAEIKSKGVSGIVASLKGKGSIMQGVQFMQGFKIYIHPSCEHTIEEFNTYTFKQDKEG
                     NWLNEPIDKNNHVIDAIRYALEKYHIRSNESNQFEVLRAGFGY"
     gene            2697..4199
                     /locus_tag="VCR92_001383"
     CDS             2697..4199
                     /locus_tag="VCR92_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEP4268444.1"
                     /translation="MYTESFRDSTGKTKTLEFRFHREARMRYQAESLESLLTEKYKLL
                     REMIEHHDKVQKPRIQELLDYAEGNNHTISEIGRRKDDDMADVRAVHNYGKYISTLKQ
                     GYLVGNPIRVEYIDGTEQQQDLLKDLSVKNNFHQLNRRLVKDLSKVGRAFELIYRSMD
                     DKTEVVRLDPREVFVIYQNNLEQSSLAGVRYYNKNQLDGTTKIVELYTDNKILKFEYD
                     GDLTLIREASSHAFGSVPITEYLNTDDGMGDYETELSLIDLYDAAQSDTANYMQDLSD
                     AILAIFGRVSFPHDVQTAEQRIEFVKVMRKARLLNLEPPVDQDGREGSVDAKYLYKQY
                     DVQGTEAYKNRIVSDIHKFTNTPDMTDSKFAGQQSGEALKWKVFGLDQERVDMQALFE
                     QSLKRRYKLIARVSQLLKEIDDFDISKLKITFTPNLPKSLQEKIEAFKALGGELSQET
                     AMAITDIVEDAKKEISLINSESKSRSQLAQKLEETSRLTDRELAHDHQKE"
     gene            4180..5742
                     /locus_tag="VCR92_001384"
     CDS             4180..5742
                     /locus_tag="VCR92_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEP4268445.1"
                     /translation="MTTRKSKYWRDRIKKEMDAKEADDISLEQSMKQLHDYHFRNIEK
                     EIESFYQRYADKEKIDLSEARKRASELDISAYQKKAKELIAKAEKLRKEGRTVTKADF
                     THQENADMAIYNLAMKTNALELLRLNIDLEMQELANGEHKLTKKFLDEGYRKEVEFQA
                     GLLGLSVASQANVKNLADAVINANFKGAKWSDNIWDRQDKLRSIISQSVQSAILKGKN
                     GLTIARDIRREFDVSASYAKRLAITEHARVQMEVGRLSMAENGFAMFDILPEPKACDV
                     CKDIAKHGPYHLDKWRIGENSPPFHPYCRCAVVGLDKKQEEKVNDKSEKFENITPNLM
                     PLFSKFASKITDLQRKIVYSADLADTGYIRTPHAFDINNTLRNKGYNYLNVDDKLITD
                     TLDSVISINSTPKNIKVYRFDDFELLGSINEQNNNIFDSGNFMDKLNQGGLSYTNDGY
                     TSASYDVKKNVMGYRPIKTEIKVPKGSHVYLTDNEEESEIILPRGTKYDIINAKINEY
                     EEIEITMEIRKE"
     gene            5746..5931
                     /locus_tag="VCR92_001385"
     CDS             5746..5931
                     /locus_tag="VCR92_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268446.1"
                     /translation="MDFSDFLNKKQKEWDESHPIPDFSAMSDEELLYQPMSEALVSER
                     FAKELSKEVRKRNLLSK"
     gene            6001..6315
                     /locus_tag="VCR92_001386"
     CDS             6001..6315
                     /locus_tag="VCR92_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268447.1"
                     /translation="MNRESKPGMESVKIGGLTYSVEKASDLQGKDGNWGLIHYKTQQI
                     KLDDSLTEQLEDQTLIHEIVHGILVEAGYTNHEEDQANRIGLILYQVLQDNDFSWLYK
                     GE"
     gene            6318..6584
                     /locus_tag="VCR92_001387"
     CDS             6318..6584
                     /locus_tag="VCR92_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268448.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAIQAKALRNQNKQIAELRAIIQ
                     QNVQAINREFVTAKNTILDNQLAIKLIGDDVGHIKQNYKRKWRK"
     gene            6728..7261
                     /locus_tag="VCR92_001388"
     CDS             6728..7261
                     /locus_tag="VCR92_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEP4268449.1"
                     /translation="MAEETQVVEMVEEQVVPEAKQPQDEKKYTDADVDAIIDKKFAKW
                     KSEQEAEKSEAKKMAKMNEKEKADYEKQKLLDELQELKNDKTRNELTAVARQMFAESE
                     INVNDDVLGLVVTLDAEQTKANVTTLANAFAKVIADDRKALVRQTTPSTGGGLRKQTN
                     YGANLASKAAQQSTKLF"
     gene            7271..7651
                     /locus_tag="VCR92_001389"
     CDS             7271..7651
                     /locus_tag="VCR92_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HEP4268450.1"
                     /translation="MNKRKVTTSKEILHNLDYEAISVTLDSKKIGKEVVPAGTVLAGV
                     SGSVFEDRKQKVKAVDNSAVESEDNICGILLTDVDLTNGDAVGSCIYRGTINADKLAD
                     SSIAGKYEVLEEELPHIVFIKGGK"
     gene            7654..8736
                     /locus_tag="VCR92_001390"
     CDS             7654..8736
                     /locus_tag="VCR92_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HEP4268451.1"
                     /translation="MALIHEIITSENIKGFYNAKNENVGNTLGENAFPPKQQLGLKLS
                     FIKGAAGKPVTLKAAAFDTKVPLRDRMTVELLDEEMPFFKEAMVVKEADRQQLSLLAQ
                     TKNQELIDTALAAIYNDKVTLIAGAKARLEAMRMEVLSKGKIHVASNGVMKDFDYGLD
                     SSQTTKPDTKWEQVDTATPLKDIEKAIEVMAERGFVPEAIIMNSKTLSLIKNASNTLD
                     VVKPMAPDGAAVTKGDLETYIADELGLKILLKDGMFVGDDGKAKKYFPDGFATLVPNG
                     NLGYTVFGTTPEQSDLLGGEATDAEVSIVETGIAITTTKTTDPVNVQTKVSMIALPSF
                     ERLEEVQIINATESEEETKKENSFEM"
     gene            8746..8988
                     /locus_tag="VCR92_001391"
     CDS             8746..8988
                     /locus_tag="VCR92_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268452.1"
                     /translation="MPRVIRAFKDKVTKVVYEVGDIYSGDRVEFLTEGGVLEPSVDFD
                     KLKVSEIKSKLDELSIEYDAKLKKSELLKLLKQTIG"
     gene            9002..9355
                     /locus_tag="VCR92_001392"
     CDS             9002..9355
                     /locus_tag="VCR92_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEP4268453.1"
                     /translation="MDAVNTSSVISNVKLDLGILDSQQDDLLNMLLKRVTDHFKAKYG
                     AVEIDSAFSFVLEDCLIARFNRRGAERAKSESVEGHTTTYYDFLDEFEPYDAMIMAKL
                     NLIKDKSRKGGLYFL"
     gene            9352..9660
                     /locus_tag="VCR92_001393"
     CDS             9352..9660
                     /locus_tag="VCR92_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268454.1"
                     /translation="MRYADRVTFVKTTDEQYNPDLGEYTHTEVISITKPCFVMDMGME
                     KSVQIFGDYQKDRKVIYLKQPYTKAFDYCEYEGKRYKAQANKLGAIVFYLEGDDSIGG
                     "
     gene            9641..10006
                     /locus_tag="VCR92_001394"
     CDS             9641..10006
                     /locus_tag="VCR92_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEP4268455.1"
                     /translation="MILLVADISLKVVGTAGLKKKLELIVKKDAVKKIVRDNGTQLQR
                     KMINKAVFTKGYSTGATRRSITMQIGDGGLSVKVKPGTHYAGYLERGTRLMSKQPFVL
                     PALKEQKVKFRKDLEALVK"
     gene            10003..10392
                     /locus_tag="VCR92_001395"
     CDS             10003..10392
                     /locus_tag="VCR92_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEP4268456.1"
                     /translation="MIKTRDQSIFDEMFKRIQSLGFKVYDYKPMTEVPYPFVEMESTD
                     AEYIPNKDDIKGSVELMLSVWGVQKKRKQVSDMASAIFSQAMSVARTDGFCWSFNIRQ
                     SSIQMLDDTTTVTPLKRAIVTLRFNLR"
     gene            10447..11070
                     /locus_tag="VCR92_001396"
     CDS             10447..11070
                     /locus_tag="VCR92_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEP4268457.1"
                     /translation="MSKAQEQTKQLEAKQGIHSILLFRLLKEASSEVATKLAFQTEHE
                     VGKSRDVDGQKTKDGIIQSVGALEYDFKATSILAKGDELAAKLEKAMEDGELVEIWDI
                     DSEEISKNGDSDNKLAKVWGINKNGTNGGNGKCLATYYQGYISSFSAKKNAEENIVIE
                     MEFAINGVGKKGFATLTDAQKAAVQYAFKDTTKSNSEETKKENSFEM"
     gene            11124..11477
                     /locus_tag="VCR92_001397"
     CDS             11124..11477
                     /locus_tag="VCR92_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HEP4268458.1"
                     /translation="MQLEIKGKTHNVKFGTRFVAEMDKNHIAERQGFKFGAGLQSSVP
                     FLIDHSVVTLAEVIYTGTITEPPRPSLNDIYDYIDEVEDIEKLFDDVLDELRQSNASK
                     LFMAQVEKDLAEAKA"
     gene            11552..11848
                     /locus_tag="VCR92_001398"
     CDS             11552..11848
                     /locus_tag="VCR92_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268459.1"
                     /translation="MTDINEIGRLTLYEYDLLMTGKALAAVDESHKAHKQAWINHQVT
                     ATKLVGGKKNKKEVPVYKKFKDFFDYEEEIRKITQEIDEGYDKKGMDLLLKANL"
     gene            11863..15498
                     /locus_tag="VCR92_001399"
     CDS             11863..15498
                     /locus_tag="VCR92_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEP4268460.1"
                     /translation="MGESYSVEAVLTAVDKTFGKTLQSAIRSIEGLEKRSTGFSSVSQ
                     KASSMFKSMLGANLAGQAISAMTRTVSSGLGSMLGEMNSSAKAWKTFDANLADIGFGK
                     KQILAAKTAMQDYATKTIYSASDMASTYAQLAAVGVKDTGKLVKAFGGLAASAENPKQ
                     AMKSISQQMTQAVGRPTVAWQDFRIMLEQAPAGMAKVAKSMGKNLDELVADIQAGRVK
                     TSDFLEAVKKAGNDKSFQKMATEFKTVDQAIDGMREGLSNKLQPAFEKVNQFGIRAIE
                     AIGKQLDKVDFSKFASNLGKFLEGINIDKIVSNISSAISSVTSKVKEFWDGFKQTGAI
                     SAFSGALQSVWEALKNVASAMSGGNWKTFGATVGGTVKHVSNFAKAVSDVLGKMDPGR
                     LRSWIATFAAVAGGFKLFEKLTGQSVIGSFLDKIGSKFGLFGNKAKEGTDKASNGARR
                     SGGIISQIFSGLGNIVKSAGTAISTAAKGIGAGIKTALSGIPPIISSLGTAISTVAQG
                     IGTGLAIAFKGLGSAIAMVPPTTWLALGAAILMVGAAFALAGTQADGISQILRTVGDV
                     VVQILQQVTDSLATLLPIIANAIGSMLPIVAGAISQIVGAVAGGLSQLVIAVSTGASL
                     VIGAFTGLLGGISGVINSISAVIQSLTGVITAVFNGIATVISSVGSAIKDVLTGLGTA
                     FEGFGNGVKSALEGVGAVIESFGSAVRNVLDGVANILDSMGTAALNAGRGVKEMAKGI
                     KMLVDLSLGDLVATLAAVASGLGKMASSAGEMTTLGSAMSKVANGMTRLATSATIAIT
                     GLTVFATTMATIKTAVATLPPVLTMAASGFTTFTTQAVAAVTGLAAINAPITMFKAQL
                     MTITPALAQAGAGFAAFVAQSSTFSTGLASAGPTIAAFNANLMSLSATTGALVASIAG
                     LSAVLSVVSAGFSQIGASATATVGQIQAFASSTTVVSSAFASMQSMIQSAMAAIVSSI
                     ITSFNQAASQMQSILSRMLSQARTFGSQLEQQMRQSGQRSGQNLARGLSSQQSAVINA
                     ISSMVNAAVSRANAGAGPMRQAGAYIGQGLAQGMYSALGAVTAAANALVAQAERAARA
                     KAMIHSPSRLFAKRVGQYIPQGVAMGIDKNADVVDDSVGGLFDSINSFDFNIADRLAS
                     IGAKFQGVIKSESSQSLSQQQEFVHTAQPAYINFSLGGNEYEAFVSDITNQQAKIEKI
                     RLKRSSW"
     gene            15530..16309
                     /locus_tag="VCR92_001400"
     CDS             15530..16309
                     /locus_tag="VCR92_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEP4268461.1"
                     /translation="MYEFNDTIRGTPKVTFNLKTTIGEKVLEEELNNDLGTFRTLTVS
                     GRDVVDLEHQTTSVLGRNGEYFHNATVEVRKLEIKAKITGKDNQSMRLQYEKLNRLIV
                     SHNQVFLSFSDEPDRNYLGIFKSKDVPEEVSNEQIIGLTFICYNPFKMSDVKTKKGTS
                     IQNGGLFQTKPIITLNLSSPTKEIKLLHVESQKYIRLTGTYTTDEIKIDMATGKITQN
                     GRNILGDLDMINSRYFELLPGNNTLQCANAAITAEFREVYL"
     gene            16306..>18051
                     /locus_tag="VCR92_001401"
     CDS             16306..>18051
                     /locus_tag="VCR92_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEP4268462.1"
                     /translation="MIYLFDKLERLVATVGTDDLLSWHFKVKNNDWDQASFEVPVDYD
                     VEPFVYFGFFNYDPNQKEDVFKLFKVIDYNLEDSKFYKGLDKAESDLDTIAIIKDKRF
                     RQSSADACIDGALEGTGYQVGKVEGITNVRTLSYYYISPRAALIKIVEAFNCEFNVRY
                     TFINNKITSRYIDLKKRFGKPTGKQFEHGNNLLKVVYEESTDDIVTCLIGRGKGEEIQ
                     HEEAEPKDVEGHLPQEERRQGYGRRIEFTDVVWSVEKGDPIDKPAGQNFVALDSAREE
                     YGLSQNGELKHRWGVFVNEEIEDKTELLKATWEELQRLSIPIRIYKAEILDIGPETWK
                     GDSVAIIYDEVKIAFETRVDEIDIDKLNFNRSVVTLGDYSVVQNRESRSRKEAVQNMI
                     DESLETITDLGMTFQEFLQGIEKRIETGKKEMEDNWRKVNLEFDNFKKKVEQEGLQFN
                     TLKEQIKEVDERTDKELEEFRATLKNLALPEEAIKKITEAIKVDDIPSLKQNFDDLKN
                     KVSETSETARLNAEIIGTDGKTRYNKNLLVGDPNRVKTYDQDYIEVEANDGGFKRGET
                     YTISFSQTCELLKKVA"
BASE COUNT         6080 a         3124 c         4016 g         4831 t
ORIGIN      
        1 aattttagta gtttcaagtt ggttgagctc aacagtaatg atgttcctaa gttcgttctt
       61 tgtgctaaga acattaattt tgttagttga aacttataat aatttcaaaa ataaataggt
      121 catcacattg tggtgacttt tttgttatgg tccacgacat ggttacttat tagttacaaa
      181 cgttgaaatt acaatgtttc gataggtcaa cgtcgtggtt ttttattatg taaaaaagaa
      241 ccacaacagt ggctcttatg cttgtaattt taattcaagc gcttcagtaa gaacttgaga
      301 aaagttgagg tttttatctt ctgctgcgtc gtttaaccat tcagggatag tcacgttttt
      361 gcggactttt ttggagtgat attttttcat ataggcaacc atatcgatgc caattaaagc
      421 aatgtcggaa tcaggatact gttcttttaa atcagaaacg gcgctagcct ttggatagtc
      481 agtatagtct tcaagggcaa aacctaagac ttcgacagcc atttcataag cctcttgaaa
      541 gtcttcacct tgagtaattg cttcaggtac atctggaaat gtaaccatga tatagtctgt
      601 gtcttgtgta aatgtagctg gataaattaa cataatgatc ctcctttgat tactgtgaga
      661 taagcacacc atctggcaag cggattattt taaacccgcc tgctttagaa tggtatcttc
      721 aagacctttt ccgaggtctt tattgtgcat tggaacaatg gtttgatgtc cgttattgtc
      781 tcggaatttt ttgtgacttc cgttttgact gacttcgtag aacccattct tttttagcag
      841 ttttatcatc tgctttgggg tcattggcat attgcttacc tcactttcta tacttatatt
      901 atacacataa acaatgtaga tgtcaatgca aaatacgcat aaaatacaca aaaggcggtg
      961 atggaaaatt gagtaaatta acactaaaac agaagcggtt tgcagatgaa tacatcatct
     1021 cagggaatgc tatggagtca gctataaagg ctgggtatag ccataattat tccaaagcac
     1081 agtcgcacaa gctattggaa aatgttggaa ttaaagagta tcttgatgaa cgatttgaaa
     1141 aaatggattc caagacaata gcagaccaaa aagaggtatt gcaatatctt tcttcggtca
     1201 tgagaggtga gcagcaagaa aaaacactca tcagcattgg agagcttggg caagaaatag
     1261 ttgatattga tgtaggagca aaagacaggt tgaaagcagc tgaattgctt ggtaagcggt
     1321 acagattgtt taccgataag atagaggctg aggtgcaagg aacggtggtg tttgtcaatg
     1381 aagacgacat accagactaa gccaaagcta gaaatcaaag ttgatttacc taaaactatc
     1441 ggtataggtt atggcgcttt ttggcgctct aaaaattttt atcgagtagt taaaggcagc
     1501 cgtggatcta aaaaatctaa aacgactgct ttaaatttta tcgtcagact gctgaagtac
     1561 ccttgggcta acttattggt catccgtaga tactcaaaca ctaacaaaca atctacttat
     1621 accgatttta aatgggcgtg taatcaatta aaggttacac acctttttaa gtttaatgag
     1681 agcttgccag agataaccgt caaggcaaca ggacaaaaaa tcttattccg tggtcttgat
     1741 gatgaactca agataacatc tattactgtt gatgtcggtt tgctctgttg ggcatggttc
     1801 gaggaggctt atcaaattga gaccgaagat aagttttcaa cagttgtcga atcaatccgc
     1861 ggtagtttag atgctcctga tttttttaaa caaataacag tcacgttcaa cccgtggtca
     1921 gaaagacatt ggcttaagcg tgtctttttt gacgaagaaa ctaaacgggc cgatacattt
     1981 tctgggacta caacatttag agtaaacgaa tggcttgatg atgtcgataa aagacgctac
     2041 gaagatttgt acaagactaa tccaaggcgg gctagaatcg tctgtgatgg tgaatggggc
     2101 gttgctgaag gtcttgtttt tgataacttt gaagtcgtag attttgatgt tgaaaaaaca
     2161 attcaacgtg tcaaagagac ttcagctggt atggactttg gttttactca agaccctaca
     2221 actcttatat gtgttgcagt tgacctcgta aacaaagaat tatggcttta caatgaacat
     2281 tatcaaaaag ctatgttgac agatcatatt gtcaaaatga taagagataa aaatatgcat
     2341 aaatcttata tcgcagctga tagcgctgaa aaacgtctaa tagcagagat aaaaagcaaa
     2401 ggtgtatctg gtattgttgc cagtcttaag ggtaaagggt ctattatgca aggagttcag
     2461 tttatgcaag gttttaaaat atacatccac ccttcttgtg aacacacaat agaagagttt
     2521 aatacttaca cttttaagca agacaaagaa ggtaattggt taaacgaacc gatagataag
     2581 aataaccacg ttattgatgc gattagatat gcgcttgaaa aataccatat cagaagcaac
     2641 gagtcaaatc agtttgaagt tcttagggct ggttttggtt actagaaagg aaaataatgt
     2701 acacagaatc atttagagat agtacgggaa agactaaaac attagagttt aggttccacc
     2761 gtgaagctcg catgaggtat caagcggaaa gtctagaaag cttgttaacc gaaaaatata
     2821 agctactccg tgaaatgatt gaacaccacg ataaagtcca aaaaccacgc atacaagagc
     2881 ttctagatta tgcagaggga aataaccaca ccatcagcga aataggccgt aggaaagacg
     2941 atgacatggc tgatgttcgt gctgtgcata actatggtaa gtatatttca acgctcaaac
     3001 agggctattt ggtgggtaat cctattcgtg tagagtatat tgatggtacc gagcagcagc
     3061 aagacctatt aaaggaccta tctgttaaaa acaatttcca ccagctgaac cgcagattag
     3121 taaaagacct atccaaggtt ggtcgagcgt ttgaattgat ttatcgcagc atggatgaca
     3181 agacagaggt cgttagacta gatccacggg aagtatttgt tatctatcaa aataacctag
     3241 agcaatcaag cttagctggt gtgcggtact ataacaaaaa tcaattagat ggtactacaa
     3301 aaattgtcga gctttacacc gataataaaa tcctgaagtt tgaatatgat ggtgatttaa
     3361 cactgattag ggaggcttcg tctcatgcgt ttggttcggt accaatcacg gagtatctca
     3421 acacagatga cggcatgggc gactacgaga cagagttgtc tttaatcgac ttgtatgatg
     3481 cagctcagtc tgatacagct aactacatgc aagatttgtc agacgcaatt ctagccattt
     3541 tcggacgtgt gtcatttccg catgatgttc agacagccga acagcgtatc gaatttgtga
     3601 aagtgatgcg taaagctaga ttgcttaacc tcgagcctcc tgtcgaccaa gacgggcgtg
     3661 agggatctgt agatgccaaa tatctatata aacaatatga cgtacaagga accgaagcct
     3721 ataaaaatcg tattgtgtcc gacatccata aatttaccaa tacgccagac atgacagaca
     3781 gtaagtttgc cggtcaacaa tccggagagg cgttgaagtg gaaagtgttt ggtcttgatc
     3841 aggagcgtgt cgacatgcaa gctttatttg agcaatctct taaacgtagg tacaaactaa
     3901 tcgctcgtgt aagccaactg cttaaagaga ttgatgactt tgacatcagc aagcttaaaa
     3961 tcacatttac gccaaaccta cctaagtcgc tacaagaaaa gattgaagcc tttaaagcat
     4021 tgggtggaga gttgtcgcaa gagacagcta tggctattac agacatcgtg gaagatgcta
     4081 agaaagaaat tagccttatc aatagcgagt cgaaatcacg tagtcaacta gcgcagaagt
     4141 tagaagaaac cagtagattg actgataggg agttagctca tgaccaccag aaagagtaaa
     4201 tactggcgtg accgtatcaa gaaagaaatg gatgctaaag aggcagacga tatctctctt
     4261 gagcaatcca tgaagcaatt gcacgattat catttcagga atatcgaaaa agaaattgag
     4321 tcgttttatc aacgttatgc tgacaaagag aaaatagacc tttcagaagc ccgtaagaga
     4381 gcttctgagc ttgatatttc tgcttaccag aagaaagcta aggaacttat tgcaaaggct
     4441 gagaagctac gaaaagaggg tagaacggta acaaaagccg acttcactca tcaagaaaat
     4501 gcagacatgg ctatttacaa cttagccatg aaaaccaacg ctttagaatt gttgcgcttg
     4561 aatatcgact tggagatgca agaacttgcc aacggcgaac acaagctaac caagaaattt
     4621 cttgacgaag gttaccgtaa agaggttgag ttccaagctg ggctattagg attatcagtt
     4681 gctagccaag cgaatgtgaa aaacttagct gatgccgtta ttaatgctaa tttcaaggga
     4741 gcaaaatggt cagataacat ttgggacaga caagataagt tacgtagcat catatctcaa
     4801 agcgtccaaa gtgctatcct aaaaggtaaa aatggcttaa ctattgcaag agatattaga
     4861 cgagagtttg atgtgtcagc atcttacgca aagcgactag cgataacgga gcatgcaagg
     4921 gttcagatgg aagttggtag attatccatg gcggagaatg gctttgctat gtttgatata
     4981 ttgcctgagc ctaaagcatg tgatgtttgc aaggatatag ctaagcatgg tccatatcac
     5041 cttgacaagt ggagaatagg ggaaaactct ccgccgtttc atccgtattg tcgttgtgca
     5101 gttgtaggat tggataagaa acaagaagaa aaagtgaatg ataaatctga aaaatttgaa
     5161 aacataacac cgaatctcat gccattattt agtaagtttg caagtaaaat aacagatttg
     5221 caacgtaaaa tagtgtactc tgctgattta gcagataccg ggtacattag aacaccgcat
     5281 gcgtttgata taaacaatac cttgcgaaat aaaggctaca attatctaaa cgttgatgat
     5341 aaactaatta ccgacacatt ggatagtgtc atctcgataa attcaactcc caaaaatata
     5401 aaagtatacc gatttgatga ttttgagtta ttaggttcaa tcaacgaaca aaacaataat
     5461 atttttgatt caggtaattt tatggataaa ttaaaccagg gaggattatc atacaccaac
     5521 gatggatata cttctgcaag ttatgatgtt aaaaaaaacg tgatgggata tcgtcctatt
     5581 aagactgaaa taaaagtacc taaaggaagc cacgtttatc ttacagataa tgaggaagaa
     5641 agtgaaatta tactaccacg agggacaaag tatgatataa ttaatgcgaa gataaatgaa
     5701 tatgaagaaa tagaaatcac tatggaaata agaaaggagt aagcgatgga tttttctgat
     5761 tttttgaata aaaaacaaaa agagtgggat gaatctcatc caattcctga ctttagtgca
     5821 atgagtgatg aagaattgct ttatcagcca atgagtgaag ctttagtgtc tgaaagattt
     5881 gctaaagagt tatctaaaga ggttagaaag cgtaatttat tatcaaaata aaaacatatt
     5941 attatagacg gaagactgtg gtcgcccgtc tttttttgta cccaaaaaca ggaggaaaac
     6001 atgaatcgtg aaagtaaacc aggtatggaa agcgtaaaaa tcggagggtt gacatactct
     6061 gttgaaaagg catcggacct gcaaggcaaa gatggcaatt ggggtcttat acactacaaa
     6121 acacaacaaa ttaaactaga tgactcatta accgagcagc tcgaagatca aacacttatc
     6181 cacgaaattg ttcatggaat tttagttgag gcaggctata ctaatcacga agaggaccaa
     6241 gctaatcgca ttggtctgat tttgtatcaa gtattgcagg ataatgattt tagctggttg
     6301 tacaaagggg aataaatatg aataaacgca tcaagaaaaa acgtaagtta gaaacagcag
     6361 ttgtgatgct tgttgcagaa aatgctatac aagcaaaagc tcttagaaat caaaacaaac
     6421 aaattgcaga gctgagagcg attatacaac aaaacgtcca agcaataaat agagagtttg
     6481 taactgctaa aaacacgatt ttagataacc aattagctat taagttaatt ggtgatgatg
     6541 ttggtcacat caagcaaaat tataagcgga agtggcgaaa ataaatttta aactggtcga
     6601 attcgacccc tttagaatca aactaagtcg taggaatacg gtttttttat tatgtccaag
     6661 cattgacgac gataaaagct atggaattaa taatcgggga cgatttaaaa cataggaggt
     6721 gccaatcatg gcagaagaaa cacaagtagt tgagatggtt gaagagcaag tggtacctga
     6781 agcaaaacaa ccgcaagacg aaaaaaagta tacagatgca gatgtggacg ctatcatcga
     6841 caaaaagttt gcgaaatgga agtcagaaca agaagctgag aaatcggaag ccaagaaaat
     6901 ggctaagatg aacgagaaag agaaagcaga ctacgaaaag cagaagctgt tagacgaatt
     6961 gcaagaacta aaaaacgata agacacgcaa tgagttaaca gcagtagctc gtcaaatgtt
     7021 tgcagaatct gaaatcaacg tcaacgatga cgtacttggt ttagttgtga ctttggacgc
     7081 agaacaaaca aaagcaaatg taacaacgct agcaaacgca tttgctaaag ttatcgctga
     7141 tgaccgcaag gctcttgtac gccagaccac tccgtcaaca ggcggtggat tgaggaaaca
     7201 aaccaattac ggtgctaact tggctagtaa ggcagcacaa caaagcacca agctttttta
     7261 ggaggaaatt atgaacaaac gtaaagtaac aacatctaaa gagattctac acaatctcga
     7321 ctatgaagct atttcagtaa ctttggattc aaaaaaaatc ggcaaggaag ttgttccagc
     7381 tgggacagtg ttagcaggtg tttcaggatc agtatttgaa gaccgcaaac agaaagttaa
     7441 agcggtcgat aacagtgccg tagaaagtga ggataacatc tgcgggattt tgcttacaga
     7501 tgtcgattta acaaatggcg atgcagtcgg ttcctgtatt tatcgtggga ctatcaatgc
     7561 agacaagctt gctgattcat ctattgcggg aaaatatgaa gtgttggaag aagaactacc
     7621 gcacattgtc tttatcaagg gaggtaaata aacatggcat tgattcacga aattatcaca
     7681 tcggaaaata tcaaaggttt ttacaatgct aaaaacgaaa atgtcggaaa cacgctaggg
     7741 gaaaacgcat ttcccccaaa acaacaatta ggactcaaac tttcgtttat taaaggtgca
     7801 gcaggcaaac ctgtcacact taaagcggca gcctttgata caaaagtgcc actacgtgac
     7861 cgtatgactg ttgaattact cgacgaagaa atgccattct tcaaagaggc tatggttgtc
     7921 aaggaagcag accgtcaaca actcagtttg ttagctcaaa ctaaaaatca agagcttatt
     7981 gacacagcgc tagcagcgat ttacaacgat aaagtaacac ttattgcagg tgcaaaagca
     8041 cgtctagaag caatgcgtat ggaagtattg tctaaaggta aaatccatgt tgcatcaaac
     8101 ggtgtcatga aagattttga ttatgggtta gattcttcgc aaacaactaa gccagataca
     8161 aaatgggaac aagtagatac cgctacacca cttaaagaca tcgaaaaagc tatcgaagta
     8221 atggcagaac gtggctttgt gccagaagct atcatcatga actctaagac acttagcctg
     8281 attaaaaatg caagtaacac tttagacgtt gtaaagccta tggcgccaga tggggcagct
     8341 gttactaaag gtgatttgga aacttatatt gctgatgaat taggtcttaa aattttgctt
     8401 aaggatggaa tgtttgtcgg agacgacggt aaagctaaaa aatacttccc agatggattt
     8461 gcaactttag ttcctaacgg caatcttggt tacacagtat ttggtactac tccagagcaa
     8521 tcagatttgc ttggtggtga ggcaacagat gctgaggtct ctattgttga aacaggtatt
     8581 gcaattacca ctactaagac aactgaccca gtgaacgtcc aaacaaaagt ttctatgatt
     8641 gctttgccat cgtttgaacg cttggaagaa gtacaaatca ttaatgcaac agaatccgaa
     8701 gaagaaacta aaaaagaaaa cagctttgaa atgtaggagg tcaatatgcc tagagtaatt
     8761 agagcattta aagataaagt aacaaaagta gtctacgaag tcggcgatat ttactcgggc
     8821 gaccgagtag agtttttgac agagggtggt gttttagaac cgtccgtaga ctttgacaag
     8881 ctgaaagtga gtgagattaa aagcaaactt gacgagttaa gcattgagta tgatgctaaa
     8941 cttaaaaaat ccgagctatt gaagctttta aagcaaacaa tcggatagtt tggaggtgtt
     9001 tatggatgca gtaaacacaa gtagcgttat aagcaatgta aagcttgatt taggcatctt
     9061 agacagtcaa caggacgatt tacttaacat gttgctaaaa cgcgttacag accattttaa
     9121 agctaaatat ggcgctgtcg aaatagacag cgcttttagt tttgttttag aagattgttt
     9181 aattgctaga tttaaccgta gaggtgccga gagggcaaaa agcgagagtg tggaaggtca
     9241 tacgacaaca tactacgact ttttggatga gtttgaacct tacgatgcca tgattatggc
     9301 aaagcttaat ttaatcaaag acaaatctcg taaaggggga ctgtactttt tatgagatat
     9361 gcagatagag ttacatttgt taaaacgacg gatgagcaat acaatcccga tttaggtgag
     9421 tatacgcaca cagaggtcat aagtatcaca aaaccttgtt ttgtgatgga catgggcatg
     9481 gaaaagtccg tacagatttt tggagattat caaaaggatc gtaaagttat ctacctgaag
     9541 cagccttata caaaagcatt tgattattgc gagtatgagg gcaagagata caaagcgcag
     9601 gcaaataagc ttggcgctat tgttttttat ctggaaggag atgattctat tggtggctga
     9661 tatatcttta aaagtagttg gaacagctgg tttaaaaaag aaacttgagc ttattgtcaa
     9721 aaaagatgcc gtcaagaaga ttgtcagaga caatgggacg cagcttcaaa ggaaaatgat
     9781 taataaagcg gtatttacaa aaggctattc aacaggtgca actagacgtt ctattaccat
     9841 gcaaatcggc gatggtggat tgagtgtcaa ggttaaacca ggaactcatt atgccggcta
     9901 ccttgaaaga ggaactcgcc ttatgagcaa acaaccgttt gttttgccag ctctaaaaga
     9961 gcaaaaagta aaatttagaa aagatttgga ggcgcttgtc aaatgattaa aactagagat
    10021 cagtctattt ttgacgaaat gtttaaacgc atccagtctt taggttttaa ggtttacgat
    10081 tataaaccga tgacggaagt tccatatcca tttgtggaaa tggaatctac tgatgcggaa
    10141 tatattccaa ataaagatga cattaaaggt tctgttgaac ttatgttgtc tgtttggggg
    10201 gtgcagaaaa aacggaagca ggtgtctgac atggcatctg ctattttttc gcaagctatg
    10261 tccgtagctc gtaccgatgg attctgttgg tcgtttaata ttaggcagtc gtctatacag
    10321 atgttagatg atacaacaac tgtgacacct cttaaacgag cgattgtcac acttagattt
    10381 aatttgagat aggaggtagt aatgtcagaa cctagcaaag caacaacaca ggaggagaaa
    10441 gaagtaatgt caaaagcaca agaacaaaca aaacaattag aagcaaaaca aggaattcat
    10501 tcaatcttgt tatttcgttt gttgaaagaa gcatctagtg aggtagcaac taaacttgct
    10561 tttcaaacag agcatgaagt aggtaaaagc cgtgacgtag atggacaaaa aactaaagat
    10621 ggtattatcc agtccgtggg ggctttggag tacgacttta aagcaacatc tattttagcc
    10681 aaaggtgacg aactagcagc taaactagaa aaagccatgg aggatggtga gcttgtagaa
    10741 atttgggata ttgattcaga agaaataagc aaaaacggcg acagcgacaa taagcttgca
    10801 aaagtttggg gtattaataa aaatggaaca aacggaggaa acggtaaatg cctagcgact
    10861 tattaccaag ggtacatttc aagcttcagc gctaagaaaa acgcagaaga aaatattgta
    10921 attgaaatgg agtttgccat caatggtgtt ggtaaaaaag ggttcgctac attaacagat
    10981 gcccaaaaag cagctgtaca gtacgcattt aaagatacaa caaaatccaa cagcgaagaa
    11041 actaaaaaag aaaacagctt tgagatgtaa cggttaggtt ggatttagta tccaaccttt
    11101 tatttttaaa ggagaaaaga ataatgcaat tggaaattaa aggtaaaact cataacgtaa
    11161 aatttggtac acgatttgtt gccgagatgg acaaaaatca tatagcagaa cgtcagggat
    11221 ttaaatttgg agctggtcta caatctagcg ttccgttttt aatcgaccac agcgttgtta
    11281 ctcttgcgga agtaatttat acaggtacaa tcaccgaacc accacgtcct agtttgaatg
    11341 atatttacga ctatattgac gaagttgaag atattgaaaa gctttttgat gatgttttag
    11401 acgaactacg tcaatcaaac gcatcaaagt tgtttatggc tcaggtggaa aaagacctgg
    11461 cggaagccaa agcgtaacaa atataaaaaa gagttattct tctcaagaaa gctttgagac
    11521 gattgtgctt aattgcatta gataccttgg catgactgac atcaatgaaa tcgggcgatt
    11581 aactttgtat gaatatgatt tattaatgac aggcaaagca ctagcggctg ttgatgaatc
    11641 acataaagct cacaaacaag cttggataaa ccaccaagtt acggcaacaa agcttgttgg
    11701 tggcaagaaa aataaaaaag aagtccctgt ttataaaaaa ttcaaggact tttttgatta
    11761 tgaggaagaa atccgaaaaa tcactcaaga aattgatgaa ggttacgaca agaaaggtat
    11821 ggatttactt ctcaaagcta acctttaagg aaaggaggtt aaatgggaga atcttattct
    11881 gttgaagcgg ttttgacagc tgttgataaa acctttggca aaacattaca atcggcaatc
    11941 cgttcaatcg aaggcttgga aaagcgttca accggttttt catcggtgtc tcaaaaagct
    12001 agttccatgt ttaaatccat gttaggagcg aatttagccg gacaagctat ctcggcaatg
    12061 acaaggacag tgtcatcagg ccttggctct atgcttggcg agatgaatag ttcagcgaaa
    12121 gcgtggaaaa cttttgacgc caatttagcg gacattggat ttggaaaaaa acaaattttg
    12181 gcagctaaaa cggcgatgca agactatgca actaaaacaa tctactcggc atcagatatg
    12241 gctagcacgt atgcacagtt agcagcggtt ggcgtgaaag ataccggaaa gctcgtaaaa
    12301 gcttttggcg gtttagctgc atctgctgaa aatccgaagc aggccatgaa gtctatcagt
    12361 caacaaatga cgcaagcagt aggaagacca acagttgcat ggcaagactt taggataatg
    12421 ctggaacagg cgcctgcagg gatggctaaa gtcgctaaat ctatgggtaa aaatcttgat
    12481 gaactcgtcg ccgatatcca ggcgggtagg gttaaaacca gcgatttttt ggaagcggta
    12541 aaaaaagcag gcaatgataa gagtttccaa aagatggcaa ctgagttcaa aactgttgac
    12601 caagccatcg acggtatgcg agaaggctta tccaacaaat tgcaaccagc gtttgaaaaa
    12661 gtgaaccaat ttggaattag agcgatcgaa gcaatcggta aacaactcga taaagttgat
    12721 ttttctaagt ttgctagtaa tcttgggaaa ttccttgaag gaattaatat cgataaaatt
    12781 gtatctaata tttcatcggc gatttcatct gtcacttcaa aggttaaaga attttgggac
    12841 ggtttcaaac aaactggagc aattagtgct ttttcaggag ctttgcagag cgtttgggaa
    12901 gctttaaaaa atgtcgctag cgccatgagc ggaggaaatt ggaagacttt tggagcaaca
    12961 gttggaggga ctgttaaaca cgtctctaac ttcgctaaag ctgtttccga tgttttagga
    13021 aagatggacc ctggcagact aagaagttgg atagctacct tcgccgcagt agctggaggc
    13081 tttaaattat tcgaaaaatt aacggggcaa agcgtcattg gttctttttt ggataaaatt
    13141 ggcagcaaat ttggcctctt tggaaacaaa gccaaagaag gaacagacaa agcctctaac
    13201 ggcgctagaa gaagcggtgg cattattagc caaatcttca gcggcttggg taatatcgtt
    13261 aagtctgctg gtacagccat atcaacagct gcaaaaggta tcggagctgg tattaaaact
    13321 gctttgtctg gaatcccccc tatcattagt tctctaggaa ccgcaatatc aacagttgcg
    13381 caaggtatag gcactgggct agcaatcgca tttaaaggcc ttggttctgc tattgccatg
    13441 gtgccgccta ccacatggct agctttagga gcggcaattt taatggttgg tgctgctttt
    13501 gccttggcag gaactcaagc tgatggcatt agtcaaattt taagaaccgt tggcgatgtt
    13561 gttgtgcaaa tcttacaaca ggtcactgat agtctagcca ctttactacc tattatcgca
    13621 aacgctattg gctctatgtt gccaattgta gctggagcta tctctcagat tgtaggcgca
    13681 gtagcgggcg gattatctca gctcgttata gccgtttcaa caggggcatc tctcgttata
    13741 ggggctttca caggacttct tggtggtatt tctggggtta ttaactccat tagcgctgtt
    13801 atccaatcgc taactggtgt gattaccgca gtattcaatg gcatagctac tgttatttca
    13861 tctgtcggtt cggctatcaa agatgtattg acgggtctag gaaccgcttt tgaaggattt
    13921 ggaaatggtg taaaatcagc tctagaaggt gttggggcag taattgaatc gtttggtagt
    13981 gcagttagga atgtccttga cggtgttgca aatatccttg attctatggg tactgcggca
    14041 cttaatgcag gccgtggcgt aaaagagatg gctaaaggca ttaaaatgct tgttgattta
    14101 tcccttggag atttggttgc tacattagca gctgtggcaa gcggtctagg gaagatggct
    14161 agctcagctg gcgaaatgac aacattaggt tctgctatga gcaaggtagc caatggtatg
    14221 acacgtctag caacaagtgc tacgatagca attactggat taacagtctt tgccaccacc
    14281 atggcaacta ttaagacagc agttgcaact ctaccgccag tcctaacgat ggcagcgagt
    14341 gggtttacca catttactac tcaggcggtg gcagcagtga ctggattggc tgcaattaat
    14401 gctccaatca ctatgtttaa agctcaacta atgacaataa caccagctct agcacaagct
    14461 ggcgctggct ttgccgcgtt tgttgctcaa tcatcaacat ttagtacagg tttagcatct
    14521 gccggtccta caatagcagc gttcaatgct aatttgatga gcttatctgc aacaacagga
    14581 gcgctagttg catcaatagc tggtttatca gctgtgcttt ctgttgtatc agctggcttt
    14641 agccaaatag gggcttctgc gacagcaact gttggtcaaa tacaagcttt tgcttctagt
    14701 acaacagttg tttcgtcagc atttgctagc atgcaatcta tgattcaatc tgccatggct
    14761 gcaatagtaa gcagcattat aacatcattt aatcaagcgg cctctcaaat gcaatcaatc
    14821 ttatctcgaa tgctatctca ggctaggaca tttgggtctc aactagagca acaaatgaga
    14881 caatcgggac agcgttcagg acaaaatctt gctcggggac tatcttctca acaaagtgct
    14941 gttattaatg ctatttctag catggttaat gctgcggtat caagagccaa cgcgggagct
    15001 ggtcctatgc gtcaagctgg agcgtacatc ggacaagggc ttgcgcaagg aatgtattca
    15061 gcgctaggag ctgtaacagc tgcagcaaac gcccttgtag cacaagccga gagagcagca
    15121 agagccaagg cgatgattca ttcgccgtca aggttgtttg caaaacgagt tggtcaatat
    15181 atcccgcaag gggtagctat gggtatcgac aaaaacgctg atgtcgttga cgactctgtt
    15241 ggcgggttat ttgatagcat caatagcttt gattttaata tcgcagatag actggctagc
    15301 attggagcta aattccaagg tgttatcaaa tcagagagtt cacaatcgtt atcgcagcaa
    15361 caagagttcg tacatacagc tcaaccagcg tatataaact ttagtttagg tggaaacgaa
    15421 tacgaagcat ttgtaagtga catcactaat caacaagcaa aaattgaaaa aatcagacta
    15481 aagagaagca gctggtagtt gtttctctta gttttttgaa aggagtaaaa tgtacgaatt
    15541 taacgatact atcagaggta ctccgaaagt tacttttaat ttaaagacaa caattggtga
    15601 aaaggtatta gaagaagaac tcaataatga tttaggtacc tttaggacat tgactgtttc
    15661 tggtcgtgat gtggtggact tagagcatca aacaacaagt gttttagggc gaaatggtga
    15721 gtatttccac aatgccacag tcgaagtcag aaaactagaa ataaaagcta aaatcactgg
    15781 aaaagataac cagtcaatgc gtttgcaata tgaaaaatta aacagattaa ttgttagtca
    15841 caatcaagtt tttttatcat tttcagacga acctgacaga aattatctag gcatctttaa
    15901 atctaaagat gtcccagaag aagtttctaa cgagcagatt ataggactaa cattcatctg
    15961 ctacaatccg tttaaaatgt ctgatgtaaa aactaaaaaa ggaacatcta tccaaaatgg
    16021 tgggttattt caaacaaagc ctatcatcac tctcaaccta tcatcaccaa caaaagaaat
    16081 taaattgttg catgtcgaaa gccagaagta tatcagattg actggaactt ataccactga
    16141 cgaaatcaag attgatatgg ccacgggtaa aattacccag aacggtcgca acatccttgg
    16201 agatttagat atgattaata gtaggtattt tgagctatta cctggtaata atacattaca
    16261 gtgtgccaat gccgccataa ccgcagagtt tagagaggtt tatctatgat atacctgttt
    16321 gataaacttg agcgattggt cgctactgtt ggtactgatg acttgctctc atggcacttt
    16381 aaggtcaaaa acaatgattg ggaccaggct agttttgaag tgccagttga ttatgacgta
    16441 gagccatttg tctactttgg tttttttaac tacgacccta atcaaaaaga agatgtcttt
    16501 aagctcttta aagtcattga ttacaaccta gaagatagca agttttacaa aggcttagac
    16561 aaagctgaga gtgatcttga taccattgcc attatcaaag ataagcgctt tagacaatcg
    16621 tccgcagatg cttgtattga tggtgcttta gagggtacgg gttatcaagt tggcaaagtt
    16681 gagggaataa caaatgttag aacacttagt tattactaca tcagtccacg agcggctctg
    16741 attaagattg tggaagcttt taactgcgag ttcaatgtca ggtatacctt tattaataac
    16801 aaaatcacta gtcgttatat cgacctcaaa aagcgctttg gaaagccaac aggcaagcaa
    16861 tttgaacatg gcaacaacct gttaaaagtc gtctacgagg aatcaacaga tgacattgtg
    16921 acttgtctga ttggcagagg taagggtgag gaaatccaac acgaagaagc tgagcctaaa
    16981 gatgtcgagg gacacttgcc acaggaagaa aggcggcaag gctacggtcg aagaatcgaa
    17041 tttactgatg ttgtctggtc ggtcgaaaaa ggcgacccga tagacaaacc agctggtcaa
    17101 aactttgtag cactagatag tgcaagggaa gaatacggct tgtctcaaaa tggtgagcta
    17161 aaacaccgct ggggtgtctt tgtcaatgag gaaatcgagg ataagacaga actcttaaaa
    17221 gcaacttggg aagaattgca gcgtttgtca atccctatca gaatttacaa ggcagaaatc
    17281 ttagacattg gtccagagac gtggaaaggc gactcagtag ccattatcta tgatgaggta
    17341 aaaatagctt ttgaaactcg ggttgatgag attgatattg acaagcttaa ttttaacagg
    17401 tcagtcgtaa cacttggtga ttacagcgtt gtccaaaatc gtgagtcacg gtctcgtaaa
    17461 gaggctgtcc aaaacatgat agatgaatct ttagagacta tcacagactt aggaatgaca
    17521 tttcaggaat ttttgcaagg catcgaaaaa cgcatcgaga ctggcaaaaa ggagatggaa
    17581 gacaattggc gaaaagttaa ccttgaattc gataacttta aaaagaaggt tgagcaagaa
    17641 ggcttgcaat tcaacacctt gaaagaacaa atcaaagaag ttgatgaacg caccgacaaa
    17701 gagctagagg aattccgagc caccctcaaa aacctagcgt taccagagga agcgattaaa
    17761 aaaatcacag aggctatcaa agttgatgac atcccgtctc ttaagcaaaa ctttgatgac
    17821 ttaaaaaaca aggtcagcga gacaagcgag acggcacgtc taaatgccga gattatcggt
    17881 acagacggta agacccgcta taacaaaaat ttattggttg gcgaccctaa ccgtgtaaaa
    17941 acctatgacc aagactatat cgaggtagaa gctaatgatg gcggctttaa gcgtggcgag
    18001 acctacacga ttagctttag tcaaacgtgt gagctactca aaaaagtagc t
//
LOCUS       DATWEK010000032        17886 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.032, whole genome shotgun sequence.
ACCESSION   DATWEK010000032 DATWEK010000000
VERSION     DATWEK010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17886
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.032"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            154..591
                     /locus_tag="VCR92_001402"
     CDS             154..591
                     /locus_tag="VCR92_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEP4268463.1"
                     /translation="MIAIIVMGHGHFASGIVSSLELIAGPQEKVTAIDFTTEMTAADV
                     QDQLSRALIPEEETLVLCDLLGGTPFKVAATLMESLPNTTCNVLSGLNLAMLIEASFA
                     RQTAASFDDLVSGLITCSKEGIVDWKTLSQQEDGTTDDELGGI"
     gene            591..1790
                     /locus_tag="VCR92_001403"
     CDS             591..1790
                     /locus_tag="VCR92_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEP4268464.1"
                     /translation="MTRSLKTIALEPIKQPERFTKEDFLSQEDITQALDLALKQVRLN
                     MDYFKEDFPTPATKDNQYAIMDNTEWTNAFWTGCLWLAYEYGGDDAIKALAQANDLSF
                     LDRVTRDIELDHHDLGFLYTPSCMAEWKLLKTPESREAALKAADKLIQRYQDKGGFIQ
                     AWGVLGKKEDYRLIIDCLLNIQLLFFASQETGDNRYRDMAINHFYASANHVIRDDASA
                     YHTFYFDPETGDPIKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKEPELIQLFKGM
                     THYFMNRLPKDQVSYWDLIFGDGSEQSRDSSATAIAVCGIHEMLKTLPDHDPDKKTYE
                     AAMHSMLRALIKDYANKNLNPGAPLLLHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWNPYW"
     gene            1826..2314
                     /locus_tag="VCR92_001404"
     CDS             1826..2314
                     /locus_tag="VCR92_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEP4268465.1"
                     /translation="MTQPNIIMTRVDERLIHGQGQLWVKFLNCNTVIVANDAVSEDKI
                     QQSLMKTVIPSSIAIRFFSIQKVIDIIHKASPAQSIFIVVKDLQDAKRLVEGGVPITE
                     INIGNIHKTDDKVAITQFISLGETDKSAIRCLAHDHHVVFNTKTTPAGNSASDVDILD
                     YI"
     gene            2333..3115
                     /locus_tag="VCR92_001405"
     CDS             2333..3115
                     /locus_tag="VCR92_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEP4268466.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGMILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVVIQFLQTFAYTAFAGAPETAKKQLQKGNIRGFKFAANGTIWAFAFMGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEFYNKPKQVDATTVQGGQQDDWI"
     gene            3102..3923
                     /locus_tag="VCR92_001406"
     CDS             3102..3923
                     /locus_tag="VCR92_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEP4268467.1"
                     /translation="MTGSNKLTKKDYLKTALRAFFLQNGFNYSNYQGIGYANVIYPAL
                     KKHFGSDKKGLYQALEDNCEFYNTNPHFLPFITSLHLVMLENDRPEEETRNIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASLASDGLVLGPIFFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAIVSRMANIVGVTVIAGLAATSVKITVPITFAAGKVDAANTAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKNKKWTTYKLVILTVIIGVIGSWLGILA"
     gene            4009..5916
                     /locus_tag="VCR92_001407"
     CDS             4009..5916
                     /locus_tag="VCR92_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEP4268468.1"
                     /translation="MSLAFTRFKETVNPNFCRNYLLDYQADSYADRKRIADLLLTNTF
                     LFEDNWDMEPCHIPYHLDPITWQEAVTDDPEWNFMLNRQTYLQTLILVYLVERDERYL
                     LTAKGFILNWIESAIPLDPKGLATRTLDTGIRCFAWVKCLIYLNLFDALTKQEERLIL
                     ASLEKQLHFLHANYLDKYSLSNWGILQTTAILLADAYFGSDLDIAAATAFARKELTQQ
                     IALQILEDGSQFEQSTMYHVEVLKALLELTALVPDYLPQLRPTLLAMSDYLLKMTGPD
                     HKQIPLGDSDFTDTRDILTLAATILEEPHLKAAAFPTLDIDSLLLLGEKGVHTFEQLP
                     VQTLPTFAHHFEHSGHITINQENYYLFFKNGPIGSSHTHSDQNSICLYYKGQPLFCDA
                     GRYTYKEEPLRYALKSASHHSTAFLEEQLPEQINSSWAYLSYPKSNYCHLRQNGHVYF
                     IEGSYQTQFSDRNNYQHDRQILILPPGMFLIIDTIQAQGNHCLVSQFILDNHLEVKTD
                     HLSDLRLISDCPFTIEETILSKKYNQYLTSHKFIKRKPFKDKGCTSTLLVPDDTKVTP
                     LTPLQTGKRNPIETALSWHLKGKQFDYSICVLQEDLIKGEKLVLLNGHKIRGKVVVIN
                     HITNEIIRLKH"
     gene            5980..6975
                     /locus_tag="VCR92_001408"
     CDS             5980..6975
                     /locus_tag="VCR92_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP4268469.1"
                     /translation="MQRKVTIKDIAELAKTSKTTVSFYLNGRFDKMSEETKNRIKSTI
                     EATNYKPSIAARSLNAKSTKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIDIKKKKVVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCIDKGYEHFIMITGNPNLLSTRIERASGFIDVLEANHLTHQEMI
                     IDENQTSSEAIAQFLQGSLTKKSLVFVPNCWALPKVFTAMKSLKFNIPEIGLVGFDNI
                     EWTKFSSPTLTTIIQPAYEEGEQATKILIDDIEGHSQEAKQQIFDCQVNWQESTF"
     gene            complement(7059..9740)
                     /locus_tag="VCR92_001409"
     CDS             complement(7059..9740)
                     /locus_tag="VCR92_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEP4268470.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLETSREGLTSAQAKERLAEYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILIVAALLSVLTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARIRRDGHVTEIDSKELVPGDIVLLEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSTAVSEDAGIGDRVNMGYQNSNVTYGRGIGVIT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQH
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGTLQSSSADIAFDNTTLRVMNFANDTKVDPSGKLIGDP
                     TETALVQFGLDHNFDVREAMVAEPRVAELPFDSDRKLMSTIHKQADGKYFIAVKGAPD
                     QLLKRVTQIEENGQIRPITDADKKTILDTNKSLAKQALRVLMMAYKYSDALPTLETEI
                     VEANLVFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAKAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEEFQKVFKQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRKSSFFDGGVKEAILYQGAFQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNQFFHVTH
                     LTITQWLVVIIGSLLMVVLVELVKAVQRSLGQDEKAI"
     gene            complement(9970..10356)
                     /locus_tag="VCR92_001410"
     CDS             complement(9970..10356)
                     /locus_tag="VCR92_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEP4268471.1"
                     /translation="MKLQLTNHIRFGDETEIIQEIHDCEWREKGGYQYLIYQNTDKEK
                     VVIKYNETELTMSRFSNPQSIMKFFAGKKVLIALPTPMGVQQFLTDTSHYHLDCSCQK
                     LDLHYHLLQAQTEMLFASYHLELSWD"
     gene            10438..11739
                     /locus_tag="VCR92_001411"
     CDS             10438..11739
                     /locus_tag="VCR92_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEP4268472.1"
                     /translation="MNEKVFRDPVHNYIHIDNPLIYDLINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTAIFEEKYADIWNKDESLVTMTAALLHDIGHGAYS
                     HTFEVLFHTDHEAFTQEIITNPETEINAILVRHALDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVEDGIVFEHSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAQHLYPEQQAYFQKTAPGLIPFFEKKANLAD
                     YIALDDGVMNTYFQVWMASEDHILSDLASRFINRKILKSVTFDQDSRGELERLRQLVE
                     SVGFDPDYYTGIHINFDLPYDIYRPELENPRTQIEMIQKDGSLAELSQLSPIVKALTG
                     TTYGDRRFYFPKEMLELDDLFAPSKETFMSYISNGHFHFSQ"
     gene            12195..13004
                     /gene="yidA"
                     /locus_tag="VCR92_001412"
     CDS             12195..13004
                     /gene="yidA"
                     /locus_tag="VCR92_001412"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEP4268473.1"
                     /translation="MSIKLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHMVIATG
                     RPIAGVISLLEQLELNHKGNHVITFNGGLVQDAETGEEIVKELMTYDDYLETEFLSRK
                     LGVHMHAITKEGIYTANRNIGKYTVHESTLVNMPIFYRTPEEMTNKEIIKMMMIDEPD
                     LLDAAIKQIPQHFFDKYTIVKSTPFYLEFMPKTVSKGNAIKHLAKKLGLDMSQTMAIG
                     DAENDRAMLEVVANPVVMENGVPELKKIAKYITKSNNDSGVAHAIRKWVLN"
     gene            13004..14230
                     /locus_tag="VCR92_001413"
     CDS             13004..14230
                     /locus_tag="VCR92_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEP4268474.1"
                     /translation="MYTYKIGISPEEHDQFVLAQPQAGLLQSSKWRKVKDNWKHERIS
                     FYENGVQVAAAACLIRKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRAL
                     FVKIDPSLVIKQTLEGKESKENDVTLSIIAFLKKLGIEWSGRTKELEDTIQPRIQANI
                     YAKDFDFDSLPKKAKQSIRTATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKS
                     YYQKLLDIYAGQSYITMASLDLPEQKKLLIQQLDKALAEQARLTDKSKPSKVAENQKT
                     IARLQKDLTILSEQLAAGKTRIPLAATLTLIYGETSENLYAGMDDDYRNYQAPLLTWY
                     ETAKEAFKRGCRWHNLGGVENQQDGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAIL
                     TYNLRKKLRSTTNGTN"
     gene            14217..15452
                     /locus_tag="VCR92_001414"
     CDS             14217..15452
                     /locus_tag="VCR92_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEP4268475.1"
                     /translation="MALIEISQEQFDHYCHSLVHHSFIQTSEMASLMAKRGAKPQFLG
                     LEKDGELKVAAMVFSQKVAGGWRMELNAGPNTNHPEELEHFYTQLKDYAKQNDVIELI
                     LKPYDNYQSFDTDGIPISHPNTDLISLLTALGYKHDGLKTGYPEGEPVWHYVKKLEGI
                     DSSRLTHSFSKKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSY
                     YQDFYDSFGDSCEFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNR
                     LKELSSQFETFQVRISEALHFLEEYGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKF
                     YSPALLQEHAMLKAIHKGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCY
                     PFPIKYHFIRLAKKLLNRY"
     gene            complement(15551..16309)
                     /locus_tag="VCR92_001415"
     CDS             complement(15551..16309)
                     /locus_tag="VCR92_001415"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEP4268476.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVEAVASKLPSTDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENTGAFTGETSPKVLAEMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIVCCGESLETYEAGKAVEFVGAQVSAALAGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQDDAQNMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVKDYMACPDVDGALVGGASLEADSFLALLDFLN"
     gene            complement(16550..17746)
                     /gene="tuf"
                     /locus_tag="VCR92_001416"
     CDS             complement(16550..17746)
                     /gene="tuf"
                     /locus_tag="VCR92_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEP4268477.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDTKFEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIKEETKKAVVTGVEMFRKQLDEGLAG
                     DNVGILLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILSKDEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTINVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
BASE COUNT         5455 a         3823 c         3340 g         5268 t
ORIGIN      
        1 taaatagtga caaaaaagac catttttgat tcttttttag cacaaccgtt cactttttct
       61 ttttcaaaaa tcttttaaaa aaagtattga caaagaattt tgaaagcgct acaatatttt
      121 tgagtaaacc ggtaaaccaa aggagattta tttatgattg ctattatcgt tatgggacat
      181 ggacattttg cgagtgggat tgtctcatcc ctagagttaa ttgccggacc acaagagaag
      241 gtaactgcaa ttgattttac tactgagatg accgccgctg atgtgcagga ccaattatct
      301 cgtgctttaa tcccagaaga ggaaacctta gttctttgtg accttctagg aggtacccct
      361 tttaaagtcg ctgcaacctt aatggaatct cttccaaaca cgacgtgtaa tgttctttct
      421 ggccttaact tagccatgct gattgaagct agttttgcaa gacaaacagc agcttctttt
      481 gacgacttag tatcaggact tataacatgt tctaaagaag gcattgttga ctggaaaact
      541 ctttctcagc aagaagacgg tacgacagac gatgagttag gaggcattta atgacacgat
      601 ctttaaaaac cattgctctt gaacctatca agcagcctga acgatttacc aaagaagact
      661 ttctaagcca agaagacatt actcaggccc ttgacttagc cctcaaacaa gttcggctta
      721 atatggacta ttttaaagaa gactttccaa cgccagctac caaagataac caatacgcca
      781 ttatggacaa cacggaatgg accaatgcct tttggacagg ttgcctttgg ttagcttacg
      841 aatacggtgg ggatgatgcc attaaagctc tggctcaagc aaatgacctt tctttcctag
      901 atcgagtaac aagagatatt gagctagatc accatgattt gggctttctt tacacccctt
      961 cttgcatggc tgagtggaaa cttttaaaaa cacctgagtc tagagaagct gctttgaaag
     1021 cagccgacaa attaatccaa cgctatcaag acaaaggcgg ctttattcag gcctgggggg
     1081 tgctgggtaa aaaagaagat taccgtttaa tcattgattg tctcctaaac atccaattac
     1141 tcttttttgc tagccaagaa actggagaca accgttaccg tgacatggcg atcaatcatt
     1201 tctacgcctc agccaatcat gtcatccgag atgacgcctc tgcttaccac accttctact
     1261 ttgatccaga aacaggcgat cctattaaag gggtcacccg acaaggttat agcgatgatt
     1321 ctgcttgggc cagagggcaa gcttggggca tttatggtat tcctttgacc tatcgtttcc
     1381 taaaagaacc tgaactcatt caactcttca agggcatgac ccattatttc atgaaccgtc
     1441 ttcctaaaga ccaggtttcc tactgggatt taatttttgg agatggtagc gagcagtctc
     1501 gtgatagttc agcaaccgcc attgctgtat gtggtattca tgaaatgtta aaaaccttac
     1561 cagatcatga tcctgataaa aaaacatatg aagctgccat gcacagcatg ctaagagcct
     1621 tgattaagga ttatgctaac aaaaatctca atcctggcgc tcctctacta cttcacggag
     1681 tctattcttg gcactctgga aaaggggttg acgagggaaa tatctgggga gactattact
     1741 atcttgaagc tctgcttcgt ttctacaaag actggaaccc ttactggtaa caaacaccga
     1801 taccgacatt taaaaaggag attttatgac acaaccaaac attatcatga cgcgagttga
     1861 tgagcgcttg attcacggac aggggcaatt atgggtcaaa ttcctcaact gcaacaccgt
     1921 tatcgtcgct aacgatgcgg tttctgaaga taagattcaa caatccctca tgaaaacagt
     1981 tattccatcc agtattgcca ttcgtttttt ctccattcaa aaagtgattg acatcattca
     2041 taaagcaagt cctgctcaaa gtatcttcat cgtggtcaaa gatttgcaag atgccaaacg
     2101 cctagttgaa gggggtgttc ccatcacaga aatcaatatc ggtaatattc ataaaactga
     2161 tgataaggtt gcgattaccc agtttatttc gctgggagaa acagacaagt ctgctattcg
     2221 ttgcttagcc catgaccacc acgtggtttt taacaccaaa acaactccag ctggcaatag
     2281 cgcctctgac gttgacatct tagattatat ttaatgaata aaggagattg atatggatat
     2341 caatttgtta caggcacttt taattggtct ttggacagcc ttttgtttca gcggaatgtt
     2401 acttggcatc tacaccaacc gttgtattat tctgtctttt ggtgtaggga tgatcttagg
     2461 tgacttgcca actgcactta gcatgggagc tatctccgaa ttagcttata tgggatttgg
     2521 agtgggtgcc ggtggtaccg ttcctcctaa tcctatcggc cctggtatct ttggtacctt
     2581 gatggctatt accagtgctg gtaaagttac cccagaagcg gccctagcct tatcaacacc
     2641 aatcgcagtt gtcatccaat ttcttcagac attcgcctat accgcttttg ctggggctcc
     2701 tgaaaccgct aaaaaacaat tgcaaaaagg caatattaga ggcttcaaat tcgctgccaa
     2761 cggcactatc tgggctttcg cttttatggg attaggcctt ggtttattag gtgccttgtc
     2821 aatggatacc ctccttcact tggttgatta tatcccacct gtcttgctca atggattgac
     2881 tgttgctggt aaaatgttac ctgctatcgg atttgccatg atcttatcag ttatggccaa
     2941 gaaggagttg attccttttg tactgattgg ttatgtttgt gcagcctacc tccaaattcc
     3001 aaccattggt atcgccatta ttggtatcat tttcgccttg aatgaatttt acaacaaacc
     3061 taaacaagtc gatgcaacaa ctgtccaagg aggccaacaa gatgactgga tctaataaat
     3121 taaccaagaa agattacctc aaaacagctc tgagagcttt cttcctacaa aatgggttta
     3181 attacagtaa ttaccaaggt atcggatacg ccaatgtcat ctatcctgcc ttgaaaaaac
     3241 attttggcag tgataaaaag ggcttatatc aagctttaga agataactgt gagttttaca
     3301 atactaaccc tcacttcctt cctttcatca ccagtctgca cttggtcatg ttagaaaatg
     3361 atcgtcctga agaagaaacc cgaaacatca aaatggcact tatggggcct ttagctggta
     3421 tcggtgactc cttatcacaa ttttgcttgg cgccactctt ttcaacgatt gcagcttcct
     3481 tagctagtga tggtttagtg ttaggtccaa ttttcttctt cctagccatg aatattatcc
     3541 taactgctat taaaatcggt tctggtctct atggctacaa ggtcggcaca agctttattg
     3601 ataaactaag cgaacaaatg gcgatagtat ctcgtatggc aaatattgtc ggtgttaccg
     3661 ttatcgctgg attagctgct acttctgtta aaataactgt tcccattact tttgcggctg
     3721 gcaaggtgga tgcggccaat acagcacaaa aatttgtgac tattcaagga atgcttgata
     3781 agattgcccc tgcactttta ccagctctct ttaccttact catgtattac cttattaaaa
     3841 acaaaaaatg gacaacctac aaattggtca ttttaactgt tatcattggt gttattggca
     3901 gttggttggg tattttagct tagttgtcac tgagattctg ttatgggttt aggaactatt
     3961 tcctagtcac attaacaggt ctcttttctt ttggaaagga aacgtcctat gtctcttgcc
     4021 ttcacacgct ttaaagaaac agtcaatcca aacttttgca ggaattacct gctagactat
     4081 caggctgaca gctatgctga tcgaaaaagg atagctgacc tactcttaac caataccttt
     4141 ttatttgaag ataattggga tatggagccc tgccacatcc cttaccactt agatcccatt
     4201 acttggcaag aggctgtcac agatgatcct gagtggaatt ttatgttaaa tcgacagacc
     4261 tatctccaaa cattaatcct cgtctacctt gttgaaagag atgaacggta tctcttaaca
     4321 gctaaaggtt tcattctcaa ttggattgaa tcagctattc ctttagatcc taaggggtta
     4381 gctactagaa ccttagatac tggcatccgt tgttttgctt gggtcaaatg tttgatttac
     4441 cttaatcttt ttgacgcctt aaccaagcaa gaggaaaggc tcatcctagc ttccctggaa
     4501 aaacaacttc actttctcca tgccaactac cttgataaat acagtctcag caattgggga
     4561 atcttgcaaa ccactgcgat tttattagct gatgcctact ttggttctga ccttgatatt
     4621 gctgcagcaa cagctttcgc tagaaaagaa ttgacgcaac aaatcgcact ccaaattctc
     4681 gaagacggca gtcaatttga acaatcaacc atgtatcatg tggaagtact caaagccctt
     4741 ctggaattaa ctgctctagt ccctgattat cttccacagc ttagacctac tttgcttgcc
     4801 atgagtgatt atctcctcaa aatgactggc cctgaccaca aacagatccc cttaggagac
     4861 agtgacttta ccgataccag agatattcta acactagcag ccactatcct tgaagaacca
     4921 cacttaaaag ctgctgcttt tcccacactt gatatcgata gtcttctcct tctaggagaa
     4981 aaaggtgtcc acacttttga acagttaccc gtccaaacct taccaacttt tgcgcatcac
     5041 tttgaacatt ccgggcacat taccatcaat caagaaaatt attatctttt tttcaaaaat
     5101 gggcccatcg gtagttccca tacccatagc gaccaaaata gtatctgtct ctattataaa
     5161 ggacaaccac ttttctgtga tgctgggcga tacacttaca aagaagaacc attacgctat
     5221 gccctaaaaa gcgctagcca tcattctacc gccttcttag aagaacaatt acctgagcag
     5281 attaatagct cctgggctta cctttcttac cccaaatcca attattgtca ccttcgacaa
     5341 aatggacacg tttactttat tgaaggtagc taccagacgc aattctctga taggaacaac
     5401 taccaacatg accgacaaat tctcatctta ccaccaggaa tgtttcttat cattgatacg
     5461 atacaggctc aaggtaacca ctgtcttgtc agtcaattta ttcttgataa tcacttagaa
     5521 gtaaagacag atcaccttag tgacctcaga ctaatcagtg actgcccttt cactatcgaa
     5581 gaaacgattt tgtcaaaaaa atacaaccaa tacctgacta gtcacaaatt catcaaacga
     5641 aaacccttta aagacaaggg ttgcaccagt accctgttag tccctgacga taccaaagtt
     5701 actcccttaa caccacttca aacaggcaaa cgcaacccaa ttgagaccgc cctttcctgg
     5761 catttaaaag gaaagcagtt tgactacagt atctgcgttc tccaagagga cttaattaaa
     5821 ggagaaaaac tagttctcct aaatggtcat aaaatcagag gaaaggtggt tgttatcaac
     5881 catatcacga atgagattat tcgattgaaa cactaaatct tttacgagtc cttatgttat
     5941 aatatgacta accattacta ttttaaagga gtgtatgcaa tgcagcgcaa agtaaccatc
     6001 aaagatattg ctgaattagc gaaaacttca aaaacaacag tttctttcta cttaaatggt
     6061 aggtttgaca agatgtctga agaaactaaa aaccgcatta aaagcacgat tgaagctacc
     6121 aattataaac caagcattgc tgccagaagt ctaaacgcca aatctactaa actcattggc
     6181 gtggttattg gtgatattac caatagtttt tccaatcaaa ttgttaaggg aattgaaagc
     6241 aaagcccagg aatttggtta ccaaattatc atcggaaaca gcaactacga cccttctcgc
     6301 gaagatgaac tcattgaaaa gatgctgaac ctcggagtgg atggctttat cattcagcct
     6361 acctctaatt tcaggaagta ttctcgcatt atcgatatta agaagaaaaa agtggtcttt
     6421 tttgatagcc aactttacga acatcgcaca aactgggtca aaactaataa ttatgatgct
     6481 gtttatgata ccattcaaca atgtatcgat aaaggttatg aacattttat catgatcacg
     6541 ggtaacccca atttacttag cactcgtatt gaacgcgctt caggcttcat tgatgtgtta
     6601 gaagctaatc atcttactca tcaagaaatg attattgatg aaaatcagac ttcttcagag
     6661 gcaatcgctc agtttttgca aggatcactg actaaaaaga gtttggtttt tgtccccaat
     6721 tgttgggctc ttccaaaagt atttacagct atgaagtctc ttaaatttaa tataccagag
     6781 attggactag taggatttga taacattgag tggacaaaat tttcttcacc aacactaaca
     6841 actattatcc aacccgccta tgaagaaggc gaacaggcta ctaagatttt aatcgatgat
     6901 attgaaggtc acagtcaaga agccaaacaa caaatttttg actgtcaagt caattggcaa
     6961 gaatcaactt tttaatgtca ggcataccaa tagtccttat cgttgtaacg attataaaaa
     7021 aaggtttgag acaattgtct caaacctttt agcgtctatt aaattgcttt ttcatcttga
     7081 ccaagtgatc gttgaacagc tttcaccaat tcaacaagaa caaccatcaa gagacttccg
     7141 ataataacca ctaaccattg tgtgatcgtc aagtgtgtca catggaagaa ttgattaaat
     7201 ccaggaacaa caactgttgc catcaatgct acaaaggcca ctggaataga atagttgaac
     7261 aatttgtttt tgaacaaccc aacagtaaag atggattggt aaacagattt cacgttgtag
     7321 gcatgtacca actgaattaa accgagggtc acataagcca tggtcaaggc atctgcatgg
     7381 acatcatggt agcttgtgtg ttctgggaac atcaaggcaa aaccataaac cccaagcacc
     7441 aaaatggttt ggaaggcacc ttggtaaaga atggcttcct tcaccccacc atcaaagaag
     7501 cttgacttac gtccacgagg tttgtgtttc atcacaccag gctcagcagg ttcaacacca
     7561 agagcaatag ctggtagggt atcagttacc aagttaatcc aaagcaagtg aactggttga
     7621 agcacatccc aaccaaacaa ggttgcaagg aagatggtaa agacttctgc catgttagca
     7681 gaaagtaaat attgaattgt tttttgaata tttgagaaga ccttacgtcc ttcttcaacc
     7741 gcaacgataa tggttgcaaa gttatcatcg gcaagaacca tgtcagaagc tcccttagaa
     7801 acctctgtac ctgtaattcc cataccaata ccaatatctg ccgttttaag agatggtgca
     7861 tcgttaaccc catcgccagt catggcaaca actttgcctt cattttgcca agccttaacg
     7921 atacgaactt tatgctcagg agatacacgg gcatacacgg agtattgttt aaagactttt
     7981 tggaactctt catctgataa ttcgttgagt tcagcacctg taaagacatg atcaacgcca
     8041 tcttcttcga taataccaag acgtttcgca atagcttttg ctgtatcttg gtggtcacca
     8101 gtaatcatga ttggacgaat gccagcttcc ttagctactt taacagcctg tgctgcttca
     8161 ggacgttcag ggtcaatcat ccctaccaaa ccagagaaga caagattagc ctcaacaatt
     8221 tctgtttcca gtgttggaag agcatcagaa tatttgtaag ccatcatcaa gacacgaaga
     8281 gcttgtttgg caagactctt attggtatca agaatggttt ttttatcagc atccgtaata
     8341 ggacgaattt gtccattttc ttcaatctgt gtgacacgct tcaacaattg gtctggcgca
     8401 cctttaacag cgatgaaata tttgccatca gcttgtttat gaatggttga catcaactta
     8461 cggtcagaat caaatggtaa ttctgccaca cgaggttctg ccaccatagc ctcacgtacg
     8521 tcaaaattgt ggtctaaccc aaactgtacc aaagctgttt ctgttgggtc accaattaac
     8581 ttccctgaag gatcaacttt agtatcatta gcaaagttca ttacacgaag tgtcgtattg
     8641 tcaaaagcaa tatcagctga tgaactttgg agtgtcccgt tggtataaac tttttcaacg
     8701 gtcatttgat tcattgtcaa ggtacccgtt ttatcagaag caatgatttc agttgatcct
     8761 agcgtttcaa cagctggtaa tttacggata atggcgttac gtttagcaag tacttgagtt
     8821 ccaagagaaa gcacaacagt aacaatcgca ggaagtccct ctggaatagc tgcaacggca
     8881 agcgctactg aagtcatcaa gccttcaagc gggtgttgac cacgcaagaa gactccaaca
     8941 gcaaaagtca ccgctgcaat cacaaggatc gcataagtca aaatcttaga aaggttgtca
     9001 aggttttgct tcaatggtgt atctgtctca tcagcattag caagcatacc agcaatatgc
     9061 ccaacctcgg tgtacatgcc agtgttagtg ataaccccaa tcccacgacc atatgtcaca
     9121 tttgagtttt gatatcccat attgacgcga tcaccaatac cggcatcttc tgaaacagcc
     9181 gttgacaagt ctttttcaac cggtacagat tctccagtaa gcgctgcttc ttcgattttt
     9241 aaggagttag cttccaaaag acgcagatca gcagggacaa catctcccgc ttctagcaag
     9301 acaatatctc cagggaccaa ttctttagag tctatctcag tcacatgccc atcacggcga
     9361 atacgagcca gtggacttga cattgatttc aaggcttcaa tagcagcttc agcttgtcct
     9421 tcttggtaaa caccaaaagc agcatttagg ataacaacag ccaagataat aatggcgtct
     9481 gtcaaacctt ccatcccctc tgtaagaact gaaagaaggg ctgccacaat caaaataata
     9541 atcatcaaat ccttaaattg atcaaggaat ttcataaata aacttcgttt ttcgccttca
     9601 tcaagctcat tacgaccata ctctgctaag cgctcttttg cttgggcaga cgtaagacct
     9661 tcgcgactgg tctctaattg agccagtacg gtctcttcac tttgcgtgta aaatgcttca
     9721 tgtctttgtt ctttagacaa attagtacct ccttggtctt tttattttag ttgttcaaat
     9781 aaaaagacct gtttattttc ttaaacaagt ctcgctgttt aagattgtac cggaaaccga
     9841 aattccgtat tgacgataca atcacggcta gccgtctgct actcccttga tataataacc
     9901 attatagtaa aaacctgact aaaaaacaag aataatccct aatcagatga tttactgcta
     9961 tctttttagt taatcccaac tcagctcaag atgatagctt gcaaatagca tttctgtttg
    10021 agcttgaagc aaatgataat gaaggtccaa tttttgacaa gaacaatcta agtggtaatg
    10081 actggtatct gtcaaaaatt gttgaacccc catcggtgta ggtagagcaa tcaggacctt
    10141 cttgcccgca aaaaatttca tgattgactg agggttggaa aaacggctca tggtcagttc
    10201 tgtctcatta tacttgatga caaccttttc cttgtcagtg ttttgataga tgaggtactg
    10261 atagccccct ttttctcgcc actcacaatc atgaatttct tgaataatct ctgtctcatc
    10321 tccaaagcga atatggttgg ttaactgtaa tttcataact cttctttcta ttctaagctc
    10381 gtctgtttat tctatcaatt tctccctatt ttatcaattt ttgatataat aaaaattatg
    10441 aatgaaaaag tatttcgtga ccctgttcac aactatatcc acattgataa tccattaatt
    10501 tatgacctta tcaataccaa agaattccaa cgcttacgac gcatcaaaca agtccctaca
    10561 acagctttca ccttccacgg cgcagaacat agccgttttt ctcactgcct aggtgtttac
    10621 gaaattgccc gtcgggtgac agctattttt gaagagaaat acgctgatat ctggaataaa
    10681 gatgaaagtc tggtcactat gacggctgcc ctcttacatg acattggtca tggagcctat
    10741 tctcatacct ttgaggttct ttttcatacg gatcacgagg cctttactca ggagataatt
    10801 accaatcctg agacagaaat caatgccatt ttggtgcgtc atgctcttga ttttccagac
    10861 aaagttgcca gcgtgattaa tcatacctat cctaacaagc aagttgtgca actgatttcc
    10921 agccagattg actgcgaccg tatggattac cttttaagag attcttattt ttctgctgcc
    10981 aattatggtc agtttgattt aatgcgcatt ctacgtgtga ttcgacctgt tgaagatggc
    11041 attgtctttg aacatagtgg tatgcatgct gtcgaggact atattgtcag tcgttttcaa
    11101 atgtacatgc aggtctattt tcatcccgcc agccgtgctg ttgagctcat cttacaaaat
    11161 ctcctcaaaa gagcccaaca cttatatcct gagcaacagg cttatttcca aaaaacagct
    11221 cctggactca tccccttctt tgaaaagaag gctaatttag cagattatat agccctagat
    11281 gacggagtca tgaatactta cttccaagtc tggatggcaa gcgaagacca tatcttatca
    11341 gatttggcca gtcgctttat taatcgaaaa attctgaagt ctgttacctt tgaccaagat
    11401 tcccgaggag agttagaacg cttgcgccaa ttggtcgaat cagttggctt tgatccagat
    11461 tattacaccg gtatccatat caacttcgac ctgccttatg atatttatcg accagagctc
    11521 gaaaatccaa gaactcagat tgaaatgata caaaaagacg ggagccttgc tgaattatct
    11581 cagttatctc ctattgtcaa agcattaaca gggacaacct acggagaccg tcgcttttat
    11641 tttccaaagg aaatgttaga gctcgatgac ctctttgctc ctagcaagga aacttttatg
    11701 agttatattt ccaatgggca ttttcacttt agtcagtaaa gccctttaag attgcagaaa
    11761 aagtcttttt tgatactttt cttaggtgat gcttatggca gcgacttcct ttggaattct
    11821 atgctttatt tttgagccta gggtctcaaa aattccgcgt aacgtcactg ccagtattga
    11881 caccactttt gccacagcaa aaagcagctg ttttggctca cgtcacacgc agaaataaga
    11941 aatcagttgt caaatcagca gagcagttca tgctttttga gcatcaaact gggtttgtct
    12001 ccattctaag attgaagaaa gagtactttc ttcaatcttt ttagttacta cagaggcgat
    12061 tgagctaaac taaaacgttt tctctcgttt ttccttaagt ttcctttctc atcccatgac
    12121 aaaagcacct atttttagta agataggagg gagaacattt ttaagataaa ccacaaaaaa
    12181 acaaggagga tgccatgtct atcaaactgg ttgctgtcga tattgatggc acattactca
    12241 ctgatgaccg tcgaattaca gatgatgttt ttcaagctgt ccaagaggct aaagcccaag
    12301 gggttcatat ggtgattgct actggcagac ctattgccgg agtgatttca ttactcgaac
    12361 aattagaact caaccacaaa ggaaaccacg ttatcacttt taatggtggc ttggtgcaag
    12421 atgccgagac cggcgaagaa attgttaaag aattgatgac ttacgacgat tatctggaaa
    12481 cggaattttt gagccgaaaa ttaggagttc acatgcatgc cattaccaaa gaaggtattt
    12541 acactgccaa tcggaatatt ggaaaataca cagttcatga atcgactttg gtaaacatgc
    12601 ctattttcta tcgcactccc gaagaaatga ccaataaaga aatcatcaaa atgatgatga
    12661 ttgatgaacc tgaccttttg gacgcggcca tcaagcaaat tcctcaacat ttctttgata
    12721 agtacaccat cgtcaagtca accccttttt atttagagtt catgccaaaa accgtcagca
    12781 agggcaatgc catcaaacac ttagctaaaa aactcgggct agatatgtca caaaccatgg
    12841 ccatcgggga tgctgaaaat gatcgtgcta tgttagaagt cgttgccaac cctgttgtca
    12901 tggaaaatgg ggttcctgaa ttgaaaaaaa tagccaaata catcaccaaa tccaacaatg
    12961 acagtggtgt ggcacatgct attcgcaagt gggtattaaa ctaatgtata catataaaat
    13021 cggaatatct cctgaagaac atgatcagtt tgtcttagca cagccacaag ctggcttact
    13081 tcaaagttca aagtggagaa aagtcaaaga taattggaaa cacgaacgca tcagctttta
    13141 tgaaaatggg gtacaagttg ctgctgctgc ttgtttaatc agaaaacttc ctcttggttt
    13201 cactatgatt tatatcccac gtgggccaat catggactac gccaattttg aactccttga
    13261 tttcgtcatt aaaacgctca aaactttcgg aaaaagcaaa cgagcgcttt ttgtcaaaat
    13321 tgatccaagt ttagtcatca aacaaacttt agaaggaaaa gaaagcaaag aaaatgatgt
    13381 gacactctct attattgctt ttctaaaaaa acttggtatc gaatggtctg gcagaacaaa
    13441 agaactcgaa gacactattc aaccaagaat acaagccaac atctacgcca aggattttga
    13501 ctttgacagc ctgcccaaaa aagccaagca atccattcgt accgctacca ataaaggtgt
    13561 taatgtcacg attggtggca gtgaattgct agacgacttt tcagccttga tgaaaaaaac
    13621 cgagaatcga aaaggcatta tccttcgagg caaatcctac tatcaaaaat tactagatat
    13681 ttatgctggt cagtcctaca ttactatggc tagtttagac ttacctgaac aaaaaaaact
    13741 cttgatccaa cagttggaca aggccttagc agaacaagca cgattaacag ataagagtaa
    13801 acctagcaaa gtagcagaaa atcaaaaaac cattgcacgg ctacaaaaag atttaaccat
    13861 tttaagcgag cagctcgctg caggcaaaac ccgcatccca ctagccgcca ccctaacctt
    13921 gatttatggc gagacttctg aaaatcttta tgcgggaatg gacgatgatt atcgcaatta
    13981 tcaagctcct cttttaacct ggtatgaaac ggctaaagaa gcttttaaaa gaggctgccg
    14041 ctggcataat ttaggaggtg tggaaaatca acaagatggt ggactctatc atttcaaagc
    14101 tagactcaac cccaccatcg aagaatttgc aggtgaattc aacattcctg tcggccttgt
    14161 ttcaagctta gccatcttga cctataactt aagaaaaaaa ttaaggagca caactaatgg
    14221 cactaattga aatttcacaa gaacaatttg accattactg ccacagtctc gtccatcatt
    14281 cctttatcca aacctcagaa atggccagct tgatggctaa aagaggggca aaaccacaat
    14341 ttcttggact tgaaaaagat ggtgaactaa aggttgctgc tatggtcttt agccaaaaag
    14401 tggctggagg ttggcgtatg gaactcaatg caggccctaa taccaatcat cccgaagaat
    14461 tagaacattt ttacactcaa cttaaagact atgccaaaca aaatgacgtt atcgaactca
    14521 ttttaaaacc ttacgacaat tatcagtcat ttgatactga tggcatccct atttctcatc
    14581 caaacactga ccttattagc cttttaacgg cgttaggata taaacatgac ggtttaaaaa
    14641 caggctatcc tgagggtgaa cctgtttggc attacgttaa aaagttagaa ggaattgatt
    14701 cctcacgttt aacccattcc ttcagcaaaa aaggaaaagc tttaataaaa aaagctaata
    14761 cttttggtat taaattacgt caactgaaac gagatgagtt acaccatttc aaagaaatca
    14821 ctgaagcaac ctctgatcgt agagattacc ttgacaaatc attatcttac tatcaggact
    14881 tttatgatag ttttggagac tcttgtgaat ttatggttgc gactcttaat tttgaagatt
    14941 accttaataa ccttaaacaa agacaactac aactagcaac cagcatcaac aaagttaaag
    15001 gagaccttgg caaaaatcct cattctgaaa aaaagcaaaa tagattaaaa gaactatcca
    15061 gccaattcga aacctttcag gtaagaattt ctgaagctct ccattttctt gaagagtacg
    15121 gaactaaaga tgtgttcctt gcgggaagtc tttttatcta taccgaacaa gaggccgtct
    15181 acctcttttc aggatcttac cccaaattta ataaatttta tagcccagct ctattacaag
    15241 agcatgctat gctcaaggca attcacaagg gcatcaaaca atataatttt cttggtatta
    15301 ctggaaagtt tgatggttca gacggtgtct tgcgctttaa acagaatttc aatggcttta
    15361 ttttgcaaaa accagggaca tttagatgtt atccatttcc aatcaaatat catttcatta
    15421 gattggcaaa aaagctatta aaccgctatt aggctaatgc atttgcctgt agaatcacct
    15481 ttattctctc atagtaagag ttaagtcatc taaaaaagaa aaggatttaa ccttttcttt
    15541 tttagatgac ttagttaagg aaatcaagca aagcaaggaa gctatcagct tcaagtgatg
    15601 caccacctac aagggcaccg tcaacatctg gacaagccat gtaatcttta acgttttcag
    15661 gttttacaga accaccgtat tgaacgcgaa ctttatcagc aacttcttgc ccaaagtctg
    15721 ctgctaccac gtcacgaaca gctttacaca tgttttgagc atcatcttga gtagctgatt
    15781 taccagtacc gatagcccag attggctcat aagctaaaac aagtgaagct acttgctctg
    15841 ctgaaagacc tgcaagtgct gctgaaactt gcgcacctac aaactcaacg gctttaccag
    15901 cttcataagt ttcaagagac tcaccacaac aaacaattgg agttaaaccg ttagcaaaga
    15961 ttgctttggc ttttttatta atgtcttcat ctgtttcatg gaagtaatca cggcgttctg
    16021 agtgaccaat cacaacatag tcagctccca tttcagcaag cacttttggt gatgtttcac
    16081 cagtgaatgc ccctgtgttt tcaaagtagc agttttgtgc agcaacttta agaactgaat
    16141 ctttagcagc ttcaatagtg gttaccaaat caacagctgg ggctgctacg gcaacatcaa
    16201 caaggtcagt tgaaggtaat ttgcttgcta cagcctcaac gaatgctttt gcttcttgag
    16261 ggtttttgtt cattttccag ttaccagcaa taattggttt acgtgacata tcacatacct
    16321 cttctttttt tatttatatc ttctatttta gcacaaatga ccgacgatta aaaggaattg
    16381 cttatatttt aggaatattt tcacaaataa aaaccctttt tctgaaagct tttcattctt
    16441 atttatcagc attttatgga gtttaagata gcaaaaagcc cccgaattgg gggcttcttc
    16501 aaacttaagt tgtctgactt aaattgctat tctgggaact taattaaaat taagcttcga
    16561 tttctgaaac gatacctgaa ccaacagtac gtccaccttc acggattgag aaagtagtac
    16621 cttgttctac ggcgattggg tggatcaact caacgttgat tgtcacgtta tcaccaggca
    16681 taaccatttc tgtacctgct ggaagttcga ttgaacctgt tacgtcagtt gtacggaagt
    16741 agaattgtgg acggtagttg ttgaagaatg gagtgtgacg tccaccttcg tctttagaaa
    16801 ggatatatac ttcacctttg aatttagtgt gtgggttgat tgaacctggt ttagcaataa
    16861 cttgaccacg ttcgatttcg tcacgttgaa caccacgaag aaggatacct acgttgtctc
    16921 ctgcaagacc ttcgtcaagt tgtttacgga acatttcaac accagtaaca acagcttttt
    16981 tagtttcttc tttgatacca acgatttcga tttcgtcgtt gacacgaaca gtaccacggt
    17041 cgatacgtcc tgaagcaact gtaccacgac ctgtgattga gaatacatct tcgactggaa
    17101 gaagcaatgg tttgtcagtg tcgcgttctg gttctggaat gtatgaatca acagtatcca
    17161 tcaattccat gatgatgtct tcaaatttag tgtcgccttc aagagcttta agagctgaac
    17221 cttggataac tggaaggtca tcacctggga aatcgtattc tgaaagaagg tcacgaattt
    17281 ccatctcaac taattcgagc aactcttcgt catcaacaag gtcaactttg ttcatgaaca
    17341 cgataaggtg tttaacacca acctgacgtg aaagaaggat gtgctcacgc gtttgtggca
    17401 ttggtccatc tgttgaagca actacaagga tagctccgtc catttgagcg gcaccagtga
    17461 tcatgttttt aacgtagtcc gcgtgtcctg gagcgtcgat gtgcgcatag tgacgagttg
    17521 cagtttcgta ctcaacgtgt gcagtgttga tagtgattcc gcgttcgcgt tcttctggag
    17581 cagcatcgat agaagcgtaa tcttttggtt ggttaactga tgaaggcaag cgacgtgcca
    17641 atacagttgt gattgcagct gttaaagtag ttttaccatg gtcaacgtgt ccgattgtac
    17701 caatgttaac gtggggttta ctacgatcgt atttttcttt tgccatttta ggaaaagcct
    17761 ccaataaaat atattttata gatagacggt aggccataca gtctaacttt accttactat
    17821 tgtagcaaat tacaatgaaa atgcaagtat tttatgtttt ttgccatttc tttatttttt
    17881 aaatag
//
LOCUS       DATWEK010000033        17829 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.033, whole genome shotgun sequence.
ACCESSION   DATWEK010000033 DATWEK010000000
VERSION     DATWEK010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17829
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.033"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(334..1779)
                     /locus_tag="VCR92_001417"
     CDS             complement(334..1779)
                     /locus_tag="VCR92_001417"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEP4268478.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARRHGGTFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGMDWDESPETHENYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEFIGMSADEKAKYIAEREAAGIVPTVRLAV
                     NESGIYKWTDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVVDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEEEIFSREQLIALFDENRLSKSPAAFDQKKMDWMSNEYLKH
                     ADFETVYALCKPFLEEAGRLTEKAEKLVELYKPQLKSADEIIPLTDLFFSDFPELTEA
                     EKEVMAGETVSTVLQAFKAKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGRDKSIEHIKNML"
     gene            complement(1962..2672)
                     /locus_tag="VCR92_001418"
     CDS             complement(1962..2672)
                     /locus_tag="VCR92_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEP4268479.1"
                     /translation="MVDNRMRFTIDQNMQFPLVEIDLEHGGSVYLQQGSMVYHTENVT
                     LNTKLNGKGSGLGKLVGAIGRSMVSGESMFITQAMSNGDGKLALAPNTPGQIVALELG
                     EKQYRLNDGAFLALDGSAQYKMERQNIGKALFGGQGGLFVMTTEGLGTLLANSFGSIK
                     KITLDGGTMTIDNAHVVAWSRELDYDIHLENGFMQSIGTGEGVVNTFRGHGEIYIQSL
                     NLEQFAGTLKRYLPTSSN"
     gene            complement(2803..3300)
                     /locus_tag="VCR92_001419"
     CDS             complement(2803..3300)
                     /locus_tag="VCR92_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEP4268480.1"
                     /translation="MSYFEHFMAANQAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFTNEGF
                     AKHIHEHLGVDVSGQDFLPFQDVEDSVRKDMAKLRASSLIPDDVVINGAVYDVATGKM
                     TQVME"
     gene            complement(3489..4850)
                     /gene="radA"
                     /locus_tag="VCR92_001420"
     CDS             complement(3489..4850)
                     /gene="radA"
                     /locus_tag="VCR92_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEP4268481.1"
                     /translation="MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKN
                     ARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRVLGGGVVPGSLILIGGDPGIGKS
                     TLLLQVSTQLANKGTVLYASGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
                     NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGE
                     IGLTGEIRRVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKA
                     VFS"
     gene            complement(4931..5377)
                     /locus_tag="VCR92_001421"
     CDS             complement(4931..5377)
                     /locus_tag="VCR92_001421"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEP4268482.1"
                     /translation="MTKIRGFELVSSFTNPDLLPKRETTHAAGYDLSVAEAVTIAPGE
                     IKLVPTGVKAYMQDGEVLYLYDRSSNPRKKGIILINSVGVIDADYYGNEANEGHIFAQ
                     MQNITDHPVTLAVGERIVQGVFMPFLIADGDQARGERTGGFGSTGQ"
     gene            complement(5487..6254)
                     /locus_tag="VCR92_001422"
     CDS             complement(5487..6254)
                     /locus_tag="VCR92_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEP4268483.1"
                     /translation="MIDLQEILANMNPNQKINYDRVMQQMAKVWAKESVRPSILMHVC
                     CAPCSTYTLEYLTQFADITVYFANSNIHPKDEYHRRAYVTQQFVSEFNAKTGNTVQFL
                     EADYVPNEYVRQVRGLEEEPEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAAKM
                     QGIDLVQVKKDAKAFMADKDLDNDFTHIRFSYRGDEM"
     gene            complement(6372..8156)
                     /locus_tag="VCR92_001423"
     CDS             complement(6372..8156)
                     /locus_tag="VCR92_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4268484.1"
                     /translation="MKTARFFWFYFKCYRFSFTVIAVAVILATYLQVKAPVFLGESLT
                     ELGKIGQAYYVAKMSGQTHFSPDLSAFNAVMFKLLMTYFFTVLANLIYSFLLTRVVSH
                     STNRMRKGLFGKLERLTVAFFDRHKDGEILSRFTSDLDNIQNSLNQSLVQVVTNIALY
                     IGLVWMMFRQDSRLALLTIASTPVALIFLVINIRLARKYTNIQQQEVSALNAFMDETI
                     SGQKAIIVQGVQEDTVTAFLKHNERVRQATFKRRLFSGQLFPVMNGMSLINTAIVIFV
                     GSTIVLSDKSMPAAAALGLVVTFVQYSQQYYQPMMQIASSWGELQLAFTGAHRIQEMF
                     DETEEVRPQNAPAFTSLKEAVAINHVDFGYLPGQKVLSDVSIVAPKGKMIAVVGPTGS
                     GKTTIMNLINRFYDVDAGSITFDGRDIRDYDLDSLRQKVGIVLQESVLFSGTITDNIR
                     FGDQTISQDMVETAARATHIHDFIMSLPKGYNTYVSDDDNVFSTGQKQLISIARTLLT
                     DPEVLILDEATSNVDTVTESKIQRAMEAIVAGRTSFVIAHRLKTILNADHIIVLKDGK
                     VIEQGNHHELLHQKGFYAELYHNQFVFE"
     gene            complement(8159..9865)
                     /locus_tag="VCR92_001424"
     CDS             complement(8159..9865)
                     /locus_tag="VCR92_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4268485.1"
                     /translation="MLKDAILRYKWYALGSFFMVIGVVASSLLQPHYLKSVLSAVIQN
                     NQEKIYEVGKPLLIIALLGLMSGAINTVLAAKIAQGVSADMREKTFRKIQDFSYANIE
                     AFNAGNLVVRLTNDINQIQSLVMMMFQILFRLPILFIGAFIMAVQTFPQLWWVIVVMV
                     ILIALIMGLVMRQMGPRFGKFQRLMDKINRIAKENLRGVRVVKSFVQEQQQYTKFKET
                     SNDLLALNLSIGYGFSLMQPALMLVSYLAVYVSINVVSTMVETDPTVIGNIASFMTYM
                     MQIMFSIIVVGSMGMQVSRAFVSMARIRQILSTEPAMTFENEKEETISGSIVFDDVSF
                     TYPNDDEPTLKHISFAIESGQMVGIVGATGSGKSTLAQLIPRLFDPQDGQILLGGKPI
                     KTLSQTTLRQSVSIVLQKAILFSGTIADNLRQGSAKADIDAMQKAAQIAQAKEFIDRM
                     DSRYESQVEERGSNLSGGQKQRLSIARGVINHPKILILDDSTSALDAKSEKRVQEALS
                     HKLEGTTTVIVAQKISSVVKADKILVLDQGQLIGEGTHAELVANNAIYREIYETQKGR
                     EE"
     gene            complement(9858..10307)
                     /locus_tag="VCR92_001425"
     CDS             complement(9858..10307)
                     /locus_tag="VCR92_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEP4268486.1"
                     /translation="MSQVIGDLRELIHQIEQISDEIAKKYDVEHLAGPQGYVLVFLAK
                     HQNQEIFVKDIEKQLRISKSVASHLVKRMVKNGFINVMPSQVDKRYKQVVLAQVGRDK
                     LPLLRECRKDIEHYFLKEITKEELLTAKKVIEQLKQNMLTYKGDNDA"
     gene            10605..11621
                     /locus_tag="VCR92_001426"
     CDS             10605..11621
                     /locus_tag="VCR92_001426"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEP4268487.1"
                     /translation="MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINT
                     KHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVV
                     VMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKD
                     IEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIE
                     HNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWH"
     gene            11654..12553
                     /gene="galU"
                     /locus_tag="VCR92_001427"
     CDS             11654..12553
                     /gene="galU"
                     /locus_tag="VCR92_001427"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEP4268488.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILIVTGKSKRSIEDHFDSNFELEYNLQAKGKIELLKLVDETTSINLHFIR
                     QSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLIDDYEETHAATI
                     AVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQDAPSDLAIIGRYLLTPEIF
                     SILEKQEPGAGNEVQLTDAIDTLNKTQRVFAREFKGKRYDVGDKFGFMKTSLDYALKH
                     PQVKDDLKAYIIQLGKALEKTKP"
     gene            complement(12652..13323)
                     /locus_tag="VCR92_001428"
     CDS             complement(12652..13323)
                     /locus_tag="VCR92_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEP4268489.1"
                     /translation="MTRLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGG
                     MFGLLVKAMPDQLWRLVTPIFIHIGFGHFFVNGLTLYFVGQIVEDLWGSRRFLLLYVL
                     SGVMGNAFTFWLSPETVAAGASTSLFGLFAAIVVLSFLGKNQALKDLGKSYQTLIVVN
                     LLMNLFMPNVSMAGHIGGVVGGVLLSIVFPTKMRVITVKKTKRMLALVSYGIILVGVL
                     VLGFL"
     gene            14011..15519
                     /locus_tag="VCR92_001429"
     CDS             14011..15519
                     /locus_tag="VCR92_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP4268490.1"
                     /translation="MLDYYLESDIIDQKILLAILLTEKELTMAAACSQTTLTALKIKQ
                     YLRQFNALFKGYLRIELIKSRIYCEVLNDKREAFFYDIFALSDTLKVLTFLLLDNPKH
                     KSIAVYTRKQGISQSKAYRLIHKLKHYLQDIGLNIVDNTVIGDELKIRYLIALLHKEY
                     GIILYDIQPADIETIHAFIFAAQKNLQPSAFLDRRFLFFDVLLMLTWKRHRYPVHLPH
                     LALFEHLKSLPIFDNIKTIAVDELAPRTRVTFSSDDFDYLFLIYLTTDNSFLSGYWTS
                     HQRQQLYHLITKDPDYHLLIHRLQALVGKYSDIHEHIPNLIPFFKRTLYNLQTLITFD
                     GYYFDQYQGNMLLLDKLETVIKDWLYDTGRQGSISSGHLHLMCLYLEQILESSIAPIN
                     ITVIESQETVGNVIGNFITSTIPSYKVELSRVNILSDNIYPYDKPVDLVVTSQKLLPF
                     LKELGVFPKETRLFGLSLDCIQQQREDLIKTILALHQNHYQKRLEELWRVPS"
     gene            complement(15868..17217)
                     /locus_tag="VCR92_001430"
     CDS             complement(15868..17217)
                     /locus_tag="VCR92_001430"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEP4268491.1"
                     /translation="MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSD
                     FLGWLDLPENYDKEEFARILTAAEKIKADSEVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKLEADANNWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEP
                     SLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDN
                     PRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEF
                     TLGYTIYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL"
     gene            complement(17673..>17829)
                     /locus_tag="VCR92_001431"
     CDS             complement(17673..>17829)
                     /locus_tag="VCR92_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="exotoxin"
                     /protein_id="HEP4268492.1"
                     /translation="LATKDSKHYEVDLFNKDDKLLSRDSFFKRYKDNKIFNSEEISHF
                     DIYLKTH"
BASE COUNT         5431 a         3787 c         3189 g         5422 t
ORIGIN      
        1 ttgattacaa ttgattagct aagtgaatac taaactagtc tctttcagca tataccaaaa
       61 aaatattgta cactaattga ttcataaaaa ccatttcttt aaatcacact aatcaaaacc
      121 tcaccgtttg ctgtcattat cacgtaagca tctcaccacc tctctttcaa atccaatctc
      181 caaaatagaa ataaactata ctatttttta ctttaccaag gtagcaagct cagataacga
      241 taaaaaagac tgaagaactt aatcttcaat ctttcgttgt cgtgactttt taactcctta
      301 aagcgtttaa aaataaaggt gaacgataca gccttatagc atgtttttga tgtgctcaat
      361 ggatttatca cgtcccaata aataaatcgt atttggtaat tctgggccat gcatttcacc
      421 agatactgca atacgaatag gcataaagag gtttttccct ttgattcctg tttctttttg
      481 aacagcctta atttgtggga aaatattttc tggtttgaag tcttcatctg acatagcttc
      541 caacttagcc ttgaaagctt gcaagactgt cgaaactgtt tcacctgcca tcacttcttt
      601 ttcggcttct gttaattcag ggaaatcaga aaagaaaagg tcagtcaatg gaataatctc
      661 atctgcagat tttaattgag gtttgtataa ttctactagc ttctcagctt tttctgtcaa
      721 acggcctgcc tcttcaagga aaggtttgca gagggcataa actgtttcaa aatccgcatg
      781 tttaagatac tcattgctca tccaatccat tttcttctgg tcaaaggcag ctggcgactt
      841 gctaaggcga ttttcatcaa aaagggcaat cagttgctca cgagagaaga tttcctcttc
      901 tccgccagga ttccagccaa gaagggcgat gaagttaaag acagcttcag gcatataacc
      961 ttttttgcgg taatcttcaa tgaattggag ggtattggtg tcgcgttttg ataatttttt
     1021 acccgtttca gaattgatga taagagtcat atgaccaaac tctggcgctt cccagccaag
     1081 agcttcatag accatcaatt gttttggcgt attggcaata tggtcatcgc cacggataac
     1141 gtgagaaatt tgcatatcat gatcatcaac aacaacggca aagttataag ttgggtagcc
     1201 atctttcttt tgaataaccc agtcaccacc gatgttacca ccttcaaact cgatatcacc
     1261 tttaaccatg tcagtccatt tgtaaatacc ggactcatta acagcaagac ggactgttgg
     1321 aacgatacct gctgcttcac gctcagcaat gtacttagct ttttcgtcag ctgacatacc
     1381 aataaattca ttgatatagc gaggcgtttc gccagctgct tcttggcgtt cacgctctgc
     1441 tgccaattct tcctcagtca cgtaagactt ataggctttt ccttcagcta acaattgatc
     1501 aatatattgt tgataaagtg ctagacgttc agactggcgg taattttcat gcgtttctgg
     1561 gctttcatcc caatccattc ctaaccattt taggttttca agttgagaac gttcaccatc
     1621 ttcaacatga cgtttacggt cagtatcttc aatacgaatg ataaaagtac ctccgtgacg
     1681 acgggcataa aggtaattaa atagggctgt gcgggcattc ccgatatgta aaagccctgt
     1741 tggacttggt gcataacgca cacgaattgg tttagacatg cttcttctcc tgttacatat
     1801 atcactcaga aacctgtggc acgaaaaaca agcaacaaat gatgatttga gcttgccaag
     1861 accttttcag acttcttcta aaatctttct tattatagca tattttactt gcttaggcga
     1921 aaaaaaatca gccctaaaaa gctgatttta tgttattttg actaatttga actagttggt
     1981 agataacgtt taagagtccc agcaaattgc tcaaggttaa gactttggat ataaatctca
     2041 ccatgacctc taaaggtatt aacaactcct tcacctgtac caattgactg cataaagcca
     2101 ttttctaaat gaatatcata atcaagttct ctgctccatg ctacaacatg ggcattatca
     2161 atagtcattg tgccaccatc aagtgtgatt ttcttgatag atccaaacga gttagcaagt
     2221 aaggtaccaa ggccttcagt tgtcatgaca aaaagtccgc cttgaccacc aaaaagtgct
     2281 tttccaatat tttgacgttc cattttgtac tgtgctgaac catctagggc tagaaaggca
     2341 ccatcattta gacgatattg tttttcacct agttctaaag caacaatctg tcctggtgta
     2401 ttgggtgcta atgctaattt accatctcca tttgacatag cttgtgtaat gaacattgat
     2461 tcaccagaaa ccatggaacg gccgatggct ccaactaatt ttcctaaacc agatccctta
     2521 ccatttaatt tggtattcaa ggttacattc tcagtatgat aaaccatact tccttgttgt
     2581 aagtaaactg atcccccatg ttccagatca atctcaacta gtggaaattg catgttttga
     2641 tcaatcgtaa atctcattct attgtcgacc atcttactct ccttgtttgt atgaataact
     2701 tgatacaatt attataacgc ttccctattt ctttgtctaa tattttcaat aatttttaaa
     2761 aataaaaaag agctgaattc agctctacaa cttggctact aactattcca ttacttgtgt
     2821 catctttcca gtagccacat cgtagacggc accgttaata acgacatcat cagggataag
     2881 agaggaggct cttagcttag ccatatcctt gcggacactg tcttccacat cttggaaggg
     2941 aaggaaatct tgccctgaaa catccacacc taagtgctca tgaatatgct tggcaaagcc
     3001 ttcattagta aaagtctgcg cgccacaatc tgtatggtgg agaaccacaa tctctcgcgt
     3061 tcccatttgc tgctgagaaa taaccagcga ccgaatcatg tcttcggtga cacgtccgcc
     3121 agcattcctt aaaatatgag catctcctag agccagcccc agagcttggg ccacatgtag
     3181 ccgtgaatcc atacaagtca caatcgctac tttagtcttg ggttttaagg gcagatgagc
     3241 tgtcccatgc aaggccacat aagcctgatt ggcagccata aaatgttcaa aataagacat
     3301 caataaactc cttttgagaa acagcagagc tatttttgct gttagtttgt cttatcttaa
     3361 catcttttat ggaaaatagc tggattaacc tcttagacgg tcggtatcgt tcgaaaagtt
     3421 aaaaaaacaa atgattggga tactttcttg acaaatttcc tcctcatttg ctcttagttt
     3481 ctgatcctct agctaaaaac tgcctttaaa acctgaccaa ccgtagtcac tccaacaacc
     3541 tcaatacctt gagggatatc aatgccttgc aaggcatttt taggagcata gaccttggta
     3601 aagccaagct ttgctgcttc attaatccgt tgctcaatac gggtcactcg ccgaatctca
     3661 cctgttaacc cgatctcgcc taagaaagct tcttgagggc tggttggttt ttccttataa
     3721 ctggatgcga tagccacagc gactgccaaa tcaatggcag gttcgtctag tttgacacca
     3781 ccagccgact tgaggtaggc atcttgattt tgtaagagta aaccacaacg cttttctaaa
     3841 actgccatta ttaggcttac gcgattgaaa tcaagtcccg tagtggttcg tctggcattg
     3901 ccaaaaacgg ttggtgtcac taaagattgc acctctgcta agataggacg acttccttcc
     3961 atcgttacaa cgacagccga tcctgttgcc ccatctaagc gttcctctaa aaagacttga
     4021 ctaggattta agacctctac caagccgcca gactgcattt caaagatgcc aatctcgtta
     4081 gtggagccaa agcggttttt cacagcccga agaatgcgaa aggtgtgatg cctttcccct
     4141 tcaaagtaga gaacggtatc caccatgtgt tctaacatac gaggcccagc caaggttcct
     4201 tccttggtga catgacccac aataaaggtt gcaatgttgt tcgtctttgc aagctgcatc
     4261 aattctgcag tgacttctct cacctgactg actgatcctt gaacacctgt aatatcaggg
     4321 ctcatgatgg tctgaatgga gtcaataatt aaaaaatctg gtttaatatt ttcaatttct
     4381 gtgcgaatag cttgcatatt ggtttcggca tagaggtaaa attcattgtc aatatcaccc
     4441 agacgctcac tccgcagttt aatctgctct gctgattctt ccccagacgc atagagaacc
     4501 gttcccttat tagcgagctg cgtagatacc tgcaagagta aggtggattt tccaatacct
     4561 ggatcaccac caattaaaat caagcttcca ggaaccacac cccctccaag aactctatta
     4621 aattcagaca tgtcagtctg tgttctgtga taactaatat tatccacatc ttttagttta
     4681 accggtctgg acttttctcc agctagacta acacgggcat ttttgacttc tttgacctct
     4741 acttcttcca caaaagaaga ccaggccgag caatttggac agcgccctaa atactttggc
     4801 gactggtagc cacactcctg acagataaag gttgcttttt tctttgccat agtaatctcc
     4861 ctcccctaga caagacaaac ccactcttaa agaataggtc tactgtcata agcatttttg
     4921 ttaaatcgct ttactgccct gtcgaaccaa aaccacctgt tcgttcacct ctggcttggt
     4981 caccatcagc aattaaaaaa ggcataaaaa ccccctgaac gatcctctca cccacagcta
     5041 atgtcacagg gtgatctgta atgttttgca tttgtgcaaa aatatgtcct tcattagcct
     5101 catttccata ataatctgca tcaatcacac ctactgaatt aatcaggata atcccttttt
     5161 ttcgtggatt tgacgaacga tcatagaggt aaagcacctc accatcttgc atgtaggcct
     5221 taacccctgt tggtaccaac ttaatctccc ctggggcaat ggttacagcc tcagcaacag
     5281 acaggtcata accagctgca tgagtcgtct cacgttttgg tagtaaatca ggattagtaa
     5341 agcttgaaac aagctcgaaa ccacgaattt ttgtcattat gataggtata tcctttcaag
     5401 tcaatcatat cctcttatta tagactattc gtaaaagaat agcaaaaagg cggtcaactt
     5461 taaacggacc acttttaatc atgccatcac atctcatccc cacgataact aaagcggatg
     5521 tgggtgaaat cattatccaa atccttgtct gccataaaag ctttggcatc ttttttcact
     5581 tgaaccaagt caataccttg cattttggca gcatagacac agccacaata gcattggcgg
     5641 taaatgtcat actcctcaca catttcaacg gatctgcgat aaccgttgtt tttcttgaaa
     5701 tcacttggca ggtatttggt ggtgtaaacc ttttgcacat cgatgcccac atcattaatg
     5761 gtttgcgaat ttttatgagg actgatggtt agggcactgg caaagtagtc aaaacctagt
     5821 tccactgctt tttgagcggt cttgtctagt cggtaatcaa aacagacacg gcaacggtcc
     5881 ccaccttctg gttcttcttc taaacctcgc acttgtcgaa cgtactcatt ggggacatag
     5941 tccgcttcga gaaactgcac ggtgttgcct gttttagcgt tgaactcgga gacaaactgt
     6001 tgtgtcacat aggctctgcg atggtattcg tccttagggt gaatattaga attggcaaag
     6061 taaaccgtaa tgtcagcaaa ctgcgtcagg tattctaggg tgtaagtgga gcatggggcg
     6121 cagcagacat gcattaaaat actgggacgc acggattcct tagcccaaac cttggccatc
     6181 tgttgcatga ccctgtcata atttatcttt tgattgggat tcatgttagc gagaatctct
     6241 tgtaaatcaa tcattgtggc tactttctaa ttgttttttc tcttgcttgc tattatacca
     6301 tatcaggaaa gaaagcttga ctgctttatt gttcaccaaa aaactccgct aagacgcgga
     6361 gctgatacca tctattcaaa gacaaattga ttgtgataca attcggcata aaagcctttt
     6421 tgatgcaata gctcatgatg atttccttgc tcaatgacct taccatcttt caacacaata
     6481 atgtgatcgg catttaaaat ggttttgagg cggtgagcaa tgacaaagct ggttcgacct
     6541 gccacgatag cttccatggc ccgttgaatt ttactttcgg taactgtatc aacatttgaa
     6601 gtggcctcat ccaaaatcaa cacttcaggg tcagtcagta gtgtcctagc aatagaaatc
     6661 aactgctttt gacctgttga aaagacattg tcatcatctg agacataggt attgtaccct
     6721 tttggtaagg acatgataaa gtcatgaata tgggtcgcac gcgcagcagt ttcaaccatg
     6781 tcttgactaa tggtctgatc accaaaacga atattatccg taatggttcc tgaaaaaaga
     6841 actgactctt gcaacacaat ccctaccttt tgacgaagac tatccaaatc gtagtcacga
     6901 atatcacggc catcaaaggt aatcgaacct gcatccacat cgtagaaacg gttaatcaag
     6961 ttcataatag tggtctttcc agaacctgtc ggtccaacca cggcaatcat tttgcccttg
     7021 ggtgcaacga ttgacacatc tgataaaact ttttgcccag gaagataccc aaaatcgacg
     7081 tggttaattg ccactgcttc ttttaagctg gtgaacgctg gtgcattttg tggacgaact
     7141 tcttcggttt catcaaacat ttcttgaata cgatgagcac cggtaaaggc cagctgcaat
     7201 tctccccaac tagacgcgat ttgcatcatg ggttggtaat attgctggga atattgtaca
     7261 aaagtaacca ctaaaccaag cgctgccgct gctggcatag atttgtcact gaggacaatt
     7321 gttgaaccga caaaaatcac gatagccgtg ttaataaggc tcattccatt catgactgga
     7381 aataattgtc ctgagaacag acggcgtttg aaggtggctt gtcgaaccct ttcgttatgt
     7441 tttaaaaagg ctgtcaccgt atcttcttgg acaccttgta caataatagc cttttgtcct
     7501 gaaatggttt catccataaa agcatttaaa gcactgactt cttgctgttg gatattggtg
     7561 tattttcttg ccaaacggat gttaatcact aaaaaaatga gagcaactgg ggttgatgcg
     7621 atggttaaca aagctaaacg gctatcttgc ctaaacatca tccagaccag gccgatgtaa
     7681 agggcaatat tagtcaccac ttgaaccaag gattggttca gcgagttttg aatattatcc
     7741 aaatcactcg tgaaacgaga aagaatctcc ccatctttat ggcggtcaaa aaaggcgacg
     7801 gttaaacgtt ctaatttacc aaacaagccc ttgcgcatgc ggttggtcga atgtgagaca
     7861 acacgtgtga gtaagaaact atatattaga ttagctaaaa cagtaaagaa ataagtcatc
     7921 aaaagcttaa acatcacggc attaaaagct gataaatcag ggctaaaatg tgtctgacca
     7981 ctcatcttag caacgtaata agcctgaccg atttttccca actcagtcaa ggactcccct
     8041 aagaagacag gagcttttac ttgtaaataa gttgctaaga taacggcaac agcaatgaca
     8101 gtaaacgaga aacgatagca tttaaaataa aaccagaaaa aacgtgctgt tttcatcact
     8161 actcctccct tcctttttgt gtctcataaa tttcacgata aatcgcatta ttagccacca
     8221 actctgcgtg tgttccttct ccaattaact gtccttggtc aaggactaag atcttatctg
     8281 ccttaactac cgatgaaatt ttttgagcaa caataactgt agttgtacct tctaatttat
     8341 gacttaaggc ttcttgaacg cgtttttcag attttgcatc aagagctgaa gtggaatcgt
     8401 ctaatataag aattttggga tgattaatga caccacgtgc aatagacaga cgttgctttt
     8461 gtccgccaga caagttacta cctcgctctt caacttggct ctcataacgg ctatccatac
     8521 gatcaataaa ttcttttgct tgcgcgattt gagcggcttt ttgcatagca tcaatatcag
     8581 cttttgctga gccttggcga aggttatcag ctatcgttcc tgaaaagaga atagcctttt
     8641 gcaacacgat ggaaaccgat tggcgcaggg ttgtttgact tagggtttta atcggctttc
     8701 ctcctaacaa aatttggcca tcttgaggat caaataagcg agggatgagc tgtgcaagcg
     8761 ttgatttccc agatcctgtt gcaccaacga tgccgaccat ttgcccagat tcaatagcaa
     8821 aagaaatgtg cttcaaggtt ggctcatcat cattaggata tgtaaaacta acatcgtcaa
     8881 atacaatgct tcctgagatg gtttcttcct tttcattttc aaatgtcatg gcaggttctg
     8941 tagacaatat ttgcctaatt ctagccatag aaacaaaagc acgactaact tgcatcccca
     9001 tggaaccaac cacaataatt gaaaacataa tttgcatcat ataagtcatg aaagaggcaa
     9061 tattcccaat cactgttgga tctgtttcga ccatggtcga aacaacattt atagaaacat
     9121 aaactgccaa ataagacacc aacattaaag ccggctgcat tagtgaaaaa ccataaccaa
     9181 tagataaatt taacgccaaa agatcattgg acgtttcttt aaatttagtg tattgttgtt
     9241 gttcttgtac aaatgattta accacgcgaa cgccacggag attttcctta gcgatgcgat
     9301 taatcttatc cattaaccgt tgaaatttac caaaacgagg acccatttga cgcatcacca
     9361 aacccatgat gagggcaatt aagataacca ttacaacaat gacccaccat aattgaggga
     9421 atgtctgaac tgccataata aacgcgccaa taaaaaggat cggcaaacga aagagaattt
     9481 gaaacatcat catgactaaa ctttggattt gattgatatc attagttagc ctaaccacaa
     9541 gattaccagc attaaaagct tcaatattgg catatgaaaa gtcttggatt tttcgaaagg
     9601 tcttctccct catatcagca gatacacctt gagctatttt agcagctaaa accgtattaa
     9661 tcgctccaga cattaaccct aaaagggcaa taataagtaa tggtttccca acctcataaa
     9721 ttttctcttg attattttga atcacagcgc ttagcacaga tttaagataa tgtggttgca
     9781 agagactact tgcaacaacc ccaataacca taaaaaatga gcctaaagca taccatttat
     9841 aacgtaagat tgcgtcttta agcatcgttg tctcctttat aagttagcat attttgcttg
     9901 agctgttcaa ttactttttt cgctgtcagc aactcttctt ttgtaatttc ttttaaaaaa
     9961 tagtgctcga tatccttacg acactcccgc aacaaaggca atttatctct accaacctgc
    10021 gctaacacta cttgcttata acgcttatcc acttgggaag gcatcacatt gataaaccca
    10081 tttttgacca tacgtttcac taaatgacta gcaactgact ttgagatacg aagttgtttt
    10141 tcaatatctt tgacaaatat ttcttgattt tggtgtttag ctaaaaaaac aagaacataa
    10201 ccttgaggac ctgctagatg ttctacatca tatttttttg caatctcatc actaatttgt
    10261 tcgatttgat gtatcaattc acgtaaatca cctatcactt gtgacatctc ttccctcctt
    10321 attttcttta atagtttcta tgataagtat tttagttctc tagataacta ttgtcaatta
    10381 aaatatcttt atttttaaaa ataagtttcc gaacttaaat aactaaaaag aacagggcaa
    10441 agccatgaca acagctcacc tgatgaagct tattaaacaa cattattaat atagctagct
    10501 ctcttgggaa cgccttatta gccaagacca tatacctttt ctaatagagc taatcaaggt
    10561 gttatgttat aatagagtga ctagctcttg aaggagaatt tagaatgaca aaacaaaaag
    10621 tagctatttt aggacctggt tcttggggaa ctgccctttc tcaggttctt aatgacaatg
    10681 gccatgacgt ccgtttatgg ggaaatattc ctgatcaaat tgaagagata aataccaagc
    10741 ataccaatag acactacttc aaagacattg tgttagacaa aaacattacg gcaactcttg
    10801 atttaggtca agccctatca gatgttgatg cggtgctttt tgttgtgcca actaaagtaa
    10861 cacgattagt tgctagacaa gttgccgcca ttttagatca taaagtagtg gtcatgcatg
    10921 cctcaaaagg tctagaacca gagacccacg aacgtttatc aactatccta gaagaagaaa
    10981 ttccagctca ttttcgtagt gaagtggtcg ttgtatcagg tcctagtcat gctgaagaaa
    11041 ctatcgttcg cgatattact ctcatcacgg cagcctcaaa agatattgaa gctgcaaagt
    11101 atgttcagtc cctctttagt aaccactact tccgacttta taccaatacc gacgtcatcg
    11161 gagttgaaac agctggtgcc ctcaaaaaca ttattgctgt tggagcagga gctctccatg
    11221 gacttgggta tggagataat gccaaagcag cggtaattac tcgtgggtta gctgaaatca
    11281 cccgtctagg cgtcaagctt ggtgctgacc cgttaaccta cagtgggtta tctggtgttg
    11341 gtgatctaat tgtaacaggt acttctgtcc attcacgtaa ctggcgggct ggagctgccc
    11401 ttggacgtgg tgaaaaatta gaagatattg aacacaacat gggtatggtt atcgaaggca
    11461 tcgcaacaac taaggtagcc tatgaaattg cccaagacct cggagtttac atgccaatta
    11521 caacagctat ttataagtcc atctacgagg gcgctgatat caaagaaagc atcctcggca
    11581 tgatgtcaaa tgaatttcgt tctgaaaatg aatggcatta agccattcgt cactaaaata
    11641 agaggaggtg ctgatgacca aagtcagaaa agctattatt cccgcagcag gtttaggcac
    11701 acgtttttta cctgcaacca aggcccttgc caaggagatg ctacctattg ttgataaacc
    11761 aactattcaa tttatcgttg aagaagctct aaaatcaggt atcgaagaaa ttcttatcgt
    11821 tactggaaaa tccaaacgct ccatagaaga tcattttgat tctaattttg aattagaata
    11881 taatttacag gctaaaggaa aaatcgaact tctaaagtta gtagacgaga ccacttctat
    11941 taaccttcac tttattcgac agagtcatcc aagaggatta ggagacgcag ttcttcaagc
    12001 aaagaccttt gttggcaatg aaccttttgt tgtcatgcta ggtgatgatc tgatggatat
    12061 tacaaatcca aatgtaaaac cattaaccaa acaattgatc gatgactatg aagaaactca
    12121 tgctgcaact attgccgtca tgagggttcc tcacgaggat gtctctaact acggtatcat
    12181 tgctcctcaa gcaaaagcag taaaaggact ctatagtgtg gatacttttg ttgaaaaacc
    12241 acaacctcaa gatgcaccta gtgatttggc aattattgga cgttacttgc tcacaccaga
    12301 aatttttagt attttagaaa aacaagaacc tggtgcaggc aatgaagttc aactgactga
    12361 tgctattgat accctcaata agacacagcg tgtctttgct cgtgagttta aagggaaacg
    12421 ctatgatgtt ggcgataaat ttgggtttat gaaaacttct ttggattatg ccctgaaaca
    12481 ccctcaagtc aaagatgact tgaaagccta catcatccaa ctgggcaaag cactagagaa
    12541 aacaaaacca taaaaataag gagggaaaat ccctccttat ttttatggtt tttgagtcgt
    12601 ttcatcctac tagccatctg agaagtaaca gtgctaacca ctcacttatt tttataaaaa
    12661 cccaagcact aacacaccaa ccaaaataat accatagctc actaaagcca acattcgctt
    12721 ggttttcttc actgttatca ctctcatctt agttggaaat actatactca gtaacacacc
    12781 acccacgaca ccgccaatat ggcctgccat actcacgttt ggcataaaaa gattcatcag
    12841 taaattgact acaattaacg tctggtatga cttgcccaaa tctttcaacg cttggttctt
    12901 acccaaaaaa ctcaatacta caatagcagc aaaaagtcca aataacgacg tcgatgctcc
    12961 tgcagctact gtttcaggac tcaaccaaaa agtaaaggca ttgcccataa cacctgataa
    13021 aacataaagt aataaaaaac ggcgtgaacc ccagaggtct tcgacaattt gaccaacaaa
    13081 atatagtgtt aacccattga caaaaaaatg accaaagccg atatgaataa atatcggagt
    13141 caccaatcgc cacaactgat ctggcattgc ttttactagt aatccaaaca tacctccaac
    13201 ttgataaata gcttgagcac cagttgctaa atgtccatat accacttgca ttgctataaa
    13261 aattaagcct gttaacccta aaaggaaaat agtaatagga tatcgtttta ataaccgtgt
    13321 catctaagat aaacctccta aacagcaata tcataaatcg tttgatttgg caatcgtatt
    13381 ggcccgctga taagcttgat tgctaacaac atccactaat aaagcttgat cattttgacg
    13441 ttttaagtct acatccatag ttcgtaaaga ctagaagagt tctttgagaa tctctttttt
    13501 catcatcttc ttatcatacc ataaattagg aaaaaggttc aagactgaca agaaattagc
    13561 tctctcaaaa aagattaaaa ataaaggcat tctaaagaat catttaagaa aactttaagg
    13621 ttactatcgt agaatgaaaa catcctaaaa agcggtttac ctaaaccgtt gggagaatag
    13681 gttttcccct tgttttccct tttcataaat ctcctgggca cctatcctcg taggtgccct
    13741 cccttgttta aacctgacca gttaaccggc tggttaggtt tttaaattta aaaagtcaac
    13801 agcaaaaata tgatatcacc cgcgtgttct tagctctctc aattatgggc taaaaacacg
    13861 catcaatcaa tctattgatg aagtttgctg ctttttgatg atctttattg tgactatact
    13921 ggtaatccta ttgattttag ttgactttta cggtagattc gctacaatat ataggattat
    13981 acaatttaat ttaaggagag aaaaattaca ttgttagatt attatttgga atccgatatt
    14041 attgaccaga aaatcctact ggctattttg ttgacagaaa aagaactgac gatggcagca
    14101 gcttgttctc aaacaacttt gactgcttta aaaataaagc agtatcttcg acaatttaac
    14161 gccttattta aagggtactt acgtattgag cttattaaat ctcgtattta ttgtgaggta
    14221 ttaaatgata agcgagaagc atttttttat gatatttttg ccttatcaga tactctaaaa
    14281 gtgttgacat tcttattact agataatccc aaacacaaat caatcgctgt ttatacacga
    14341 aaacaaggga tatcccagtc aaaagcttat cgtcttattc ataaattaaa acattattta
    14401 caagacattg gtttaaatat tgtagacaat actgttatcg gagatgaact taaaatacgg
    14461 tatttgattg ctcttttaca taaagagtac ggcattatat tatatgatat acaacctgca
    14521 gacattgaaa cgattcatgc ttttatcttt gcagcacaaa aaaacttaca accttctgcc
    14581 tttttagata gacgcttctt gttttttgat gtgctgttga tgttgacttg gaagcgccat
    14641 cgctatcctg ttcatttgcc tcatttagct ctttttgaac atctcaaatc cttgcctatt
    14701 tttgacaata tcaaaaccat tgccgtggat gagctagcac ctcgaactcg tgtcacattt
    14761 tcgtctgatg attttgacta tctcttttta atttatttaa cgactgataa ctccttcttg
    14821 agtgggtact ggacaagtca tcagcgacaa caactttacc atttaatcac caaagatccc
    14881 gattatcatt tactaatcca tcgtcttcag gcactagttg gaaaatattc cgatattcat
    14941 gagcatatcc ctaacttaat tccttttttc aaaagaactc tctacaattt acaaacttta
    15001 attacctttg atggttatta ttttgatcaa tatcaaggca acatgctact actagataag
    15061 cttgaaaccg ttatcaaaga ttggctttat gacacaggcc gtcaaggcag tattagttct
    15121 ggtcacttac acttgatgtg tttatacctt gagcagatct tggaaagctc tattgctcca
    15181 atcaatatta ctgttattga gagccaagaa actgttggta acgttatagg taatttcatc
    15241 acctcaacta tcccttctta caaagttgaa ctgtcacggg tcaatatctt atctgataat
    15301 atttatccct atgataaacc tgtagatctg gttgtgacca gtcagaagct cttgcctttc
    15361 ttaaaagaac tcggtgtttt tcccaaagag acccgcttgt ttggtttgag tttggactgt
    15421 atccaacagc agcgcgaaga tttaatcaaa accatcttag ccttgcacca gaaccactac
    15481 caaaaacgtt tagaagaact ttggagagtt ccttcttaat tttttgacag tccctcctag
    15541 atacttttac agtctagggg ggtctttaag gttgtcactt gcaaccttga taagctctct
    15601 ttttaaccat tgctatttgc ttagaaacag aactggaact gttttagcgg ttcaactcct
    15661 cttgtaggat cttcttccct tttttgaagg ttttatctga aatttggcat aataaagtgc
    15721 gctcccatgt tctggaagcg cactttatta tcgcttttac ttaaccttgt atccacttga
    15781 tgatggaagt gccgccccaa ttcttagatt gcttggctaa cttttaagct cttgtacaag
    15841 gaagaagtct ttttgactat ctgttgatta gaggcgagca ttaagctctg ctgataatgc
    15901 ttcaaaacct ggttttccaa gaagcgcaaa catattacgt ttgtaagctt caacacctgg
    15961 ttgatcaaat gggttaacag cattcatgta gcctgaaaca gcgatggcaa gctcaaagaa
    16021 gtaaatagtg taaccaaggg taaactcgtc ttgagctgga agagtgacaa acatgtttgg
    16081 cacgccacca tctgtgtggg caagaagcac accatctgtg gctttcttat taacaaaatc
    16141 aacgtcttta ccttgaaggt aaccaagacc atctaggtct tctgctaatt caggaatgat
    16201 aacattttta cgagggttat caacacgaat aactgtttca aagaggttac ggtaaccttc
    16261 ttggataaat tgaccaagtg agtgaaggtc tgttgagaag ttagctgaag ttgggtaaat
    16321 ccctttttga tcttttcctt ctgattcacc agctaattgt ttccaccatt cgccaaagta
    16381 ctgaagagat ggctcgtagt tagccaagat ttcagtgatg tagcctttac ggtaaagcac
    16441 attacgaaca gcagcgtatt ggtaagcaat gttttcagag attttgtctg aagaaaggtc
    16501 tttacgagca gcatttgccc cttccataag agcagtaata tctgcacctg atgcagcaat
    16561 tggaagcaaa ccaacagcag tcaagactga gaaacgacca ccaacattat ctggcaccac
    16621 aaatgtttcc cagttgttag cgtcagcttc taacttaaca gcacccttaa ctttgtctgt
    16681 ggtagcgtag atacgtttgt tagcttcttc ttggccatat tttttaacca aaagttcttt
    16741 gaacacgcga aaagcaatag ctggctcagt ggttgtacct gatttagaga tcacgtttac
    16801 tgagaattct ttgtcttgaa cgtactctac aaggtcagct aagtaagttg atgaaataga
    16861 gtttccagcg taaagaattt gtggggcttt gcgctctttg gcagtttgca agttagcaaa
    16921 atgatgattt aaaaaatcaa tcgctgcttt ggcaccaagg tatgacccac cgataccgat
    16981 caccacaaga acttcgctgt ctgccttaat cttttcagca gcagtcaaga tacgtgcaaa
    17041 ttcctctttg tcatagtttt ctggaagatc aagccagccc aagaaatctg aacctggtcc
    17101 agttccttca cgcaataact tgtcagcttc tgtgacttgg ccttgtaaaa aatcaatttc
    17161 atgttgtccc gcaaatgact cgaggacttt tgaataatca aatgtaatat gtgacatgag
    17221 tttcgctccc ttaaaatttt aagtttcatt agtatgataa ccttttctat ctaatatttc
    17281 aatggttttt agtggttttc acctgtgaaa aagctaggtt ttttgaaaag gttttcgttt
    17341 tttcagacat aaaaaatgtg tcaatgcaag catattctca tcatagtggt tttttaagag
    17401 aaaataggat ttcatatttc ctaaaaatat catgaaaaaa ggccctgagg ccgctttacc
    17461 gtaataactt attttaagga ttttatcatt tcaacacggg taataacccc atcatgcata
    17521 tgatcaatgc ataaagccac acctacaaag gcaattgaag ccccaatcac ctgtaaatac
    17581 tttctcatgc tatcttctta acattactta ctctcattat ctaaaaatgg caatcatttg
    17641 aatacttaaa aagcaaaggg gggagaatag cactagtgcg tttttaagta gatatcaaaa
    17701 tgactaattt cttcactatt aaaaatctta ttatctttat accttttaaa gaaactgtct
    17761 cgacttaaaa gcttatcatc cttattaaat aaatcaactt cataatgttt actatcttta
    17821 gtagcaagg
//
LOCUS       DATWEK010000034        17717 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.034, whole genome shotgun sequence.
ACCESSION   DATWEK010000034 DATWEK010000000
VERSION     DATWEK010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17717
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.034"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            100..804
                     /locus_tag="VCR92_001432"
     CDS             100..804
                     /locus_tag="VCR92_001432"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEP4268493.1"
                     /translation="MTNQLIYKGKAKDIYSTKDENVIRTVYKDQATMLNGARKETIDG
                     KGALNNQISSLIFEKLNKAGVVTHYIEQISKNEQLNKKVDIIPLEVVLRNVIAGSFSK
                     RFGVEEGRVLETPIVEFYYKNDDLNDPFINDEHVKFLGIVNDEEIAYLKGETRRINEL
                     LKGWFAQIGLNLIDFKLEFGFDQEGTIILADEFSPDNCRLWDKNGNHMDKDVFRRDLG
                     NLTDVYQVVLEKLIAL"
     gene            928..4653
                     /locus_tag="VCR92_001433"
     CDS             928..4653
                     /locus_tag="VCR92_001433"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEP4268494.1"
                     /translation="MNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKALRIVQVYDV
                     FNLAEDLLARAEKHIFSEQVTDCLLTETEITAELDKVAFFAIESLPGQFDQRAVSSQE
                     ALLLFGSDSQVKVNTAQLYLVNKDIAEAELEAVKNYLLNPVDSRFKDITLPLEEQAFS
                     VSDKTIPNLDFFETYKADDFTAYKVEQGLAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITTPIAETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPEAGDVVILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRAGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPSDVDAFIA
                     ACNKENIDAVVVATVTEKPNLVMTWNDETIVDLERRFLDTNGVRVVVDAKVVDKDLTV
                     PEARITSAETLEADTLKVLSDLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTES
                     SVQKLPVQHGVTTTASVMAQGYNAYIAEWSPYHGAAYAVIEATARLVATGADWSRARF
                     SYQEYFERMDKQAERFGQPVSALLGSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLV
                     AFGVTTADSRKILSPEFKAAGENIYYIPGQAISEDIDFDLIKANFSQFEAIQTQHKIT
                     AASAVKYGGVLESFALMTFGNRIGASVEIAELDSSLTAQLGGFVFTSAEEIADAVKIG
                     QTQADFTVTVNGNDLAGASLLAAFEGKLEEVYPTEFEQTDVLEEVPAVVSDTVIKAKE
                     TIEKPVVYIPVFPGTNSEYDSAKAFEQVGASVNLVPFVTLNEVAIAESVDTMVANIAK
                     ANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRAAIDSFIEKGGLIIGICNGFQALVK
                     SGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRIANTNSPWLAGVEVGDIHAIPVS
                     HGEGKFVVSASEFAELRDNGQIWSQYVDFDGQPSMDSKYNPNGSVNAIEGITSKNGQI
                     IGKMGHSERWEDGLFQNIPGNKDQTLFASAVKYFTGK"
     gene            4814..6268
                     /locus_tag="VCR92_001434"
     CDS             4814..6268
                     /locus_tag="VCR92_001434"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEP4268495.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPQAAQVTYFGLHSLQHRGQEGAGI
                     VSNDNGKLYGYRNVGLLSEVFKNQSELDNLTGNAAIGHVRYATAGSADIRNIQPFLYK
                     FHDGQFALCHNGNLTNAISLRKELEKQGAIFNASSDTEILMHLIRRSHNSSFMGKVKE
                     ALNTVKGGFAYLLMTENKLIAALDPNAFRPLSIGQMQNGAWVISSETCAFEVVGAKWV
                     RDVEPGEVILIDDRGIQCDRYTDETQLAICSMEYVYFARPDSTIHGVNVHTARKNMGK
                     RLAQEFKQDADIVIGVPNSSLSAAMGFAEESGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMIDDSIVRGTTSRRIVGLLREAGASEVHVAIASPELKY
                     PCFYGIDIQTRRELISANHAADEVCDIIGADSLTYLSLDGLIESIGLETKAPNGGLCV
                     AYFDGHYPTPLYDYEEEYLRSLEEKTSFYIQKVK"
     gene            6296..7318
                     /locus_tag="VCR92_001435"
     CDS             6296..7318
                     /locus_tag="VCR92_001435"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEP4268496.1"
                     /translation="MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVREPVLVSGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNNPVKFEEVVSGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQLIDGSKVKEGDILLGLASSGIHSNGYSLVRRVFADYTGKELLPELEGKQLK
                     DVLLEPTRIYVRAALPLIKEELINGIGHITGGGFIENVPRMFADDLAAEIDEDKVPVL
                     PIFKALEKYGDIKHEEMFEIFNMGVGLMLAVSPENVNRVKELLDEPVYEIGRIIKKAD
                     DSVVIK"
     gene            7486..8040
                     /gene="purN"
                     /locus_tag="VCR92_001436"
     CDS             7486..8040
                     /gene="purN"
                     /locus_tag="VCR92_001436"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEP4268497.1"
                     /translation="MKIAVFASGNGSNFQVIAEQFPVSFVFSDHRDAYVLERAQNLAI
                     PSFAFELKEFENKAAYEQAIVDLLDKHEIDLVCLTGYMKIVGETLLLAYEGRIINIHP
                     AYLPEFPGAHGIEDAWEAGVDQSGVTIHWVDSGVDTGQVIQQVRVPRLADDSLESFET
                     RIHETEYQLYPAVLDSLGVERKVI"
     gene            8224..9771
                     /gene="purH"
                     /locus_tag="VCR92_001437"
     CDS             8224..9771
                     /gene="purH"
                     /locus_tag="VCR92_001437"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEP4268498.1"
                     /translation="MTKRALISVSDKSGIVDFAKELKNLGWDIISTGGTKVALDNAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVNL
                     YPFKETILRPDITYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADA
                     GQTTFETRQRLAAKVFRHTAAYDALIAEYFTTQVGEAKPEKLTITYDLKQAMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVVLKHM
                     NPCGIGQADDIETAWDYAYEADPVSIFGGIVVLNREVDAATAKKMHPIFLEIIIAPSY
                     SEEALAILTNKKKNLRILELPFDAQAASEVEAEYTGVVGGLLVQNQDVVAENPSDWQV
                     VTDRQPTEQEATALEFAWKAIKYVKSNGIIITNDHMTLGLGAGQTNRVGSVKIAIEQA
                     KDHLDGAVLASDAFFPFADNIEEIAAAGIKAIIQPGGSVRDQDSIDAANKHGLTMIFT
                     GVRHFRH"
     gene            complement(9829..10953)
                     /locus_tag="VCR92_001438"
     CDS             complement(9829..10953)
                     /locus_tag="VCR92_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEP4268499.1"
                     /translation="MKKFHRFLVSGVILLGFNGLVPTMPSTLISQQENLVHAAVLGDN
                     YPSKWKKGNGIDSWNMYIRQCTSFAAFRLSSANGFQLPKGYGNACTWGHIAKNQGYPV
                     NKTPSIGAIAWFDKNAYQSNAAYGHVAWVADIRGDTVTIEEYNYNAGQGPERYHKRQI
                     PKSQVSGYIHFKDLSSQTSHSYPRQLKHISQASFDPSGTYHFTTRLPVKGQTSIDSPD
                     LAYYEAGQSVYYDKVVTAGGYTWLSYLSFSGNRRYIPIKEPAQSVVQNDNTKPSIKVG
                     DTVTFPGVFRVDQLVNNLIVNKELAGGDPTPLNWIDPTPLDETDNQGKVLGDQILRVG
                     EYFTVTGSYKVLKIDQPSNGIYVQIGSRGTWVNADKANKL"
     gene            11206..12471
                     /gene="purD"
                     /locus_tag="VCR92_001439"
     CDS             11206..12471
                     /gene="purD"
                     /locus_tag="VCR92_001439"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEP4268500.1"
                     /translation="MKLLVVGSGGREHAIAKKLLASKGVDQVFVAPGNDGMTLDGLDL
                     VNIVVSEHSRLIAFAKENEISWAFIGPDDALAAGIVDDFNSAGLRAFGPTKAAAELEW
                     SKDFAKEIMVKYNVPTAAYGTFSDFEKAKAYIEEQGVPIVVKADGLALGKGVVVAETV
                     EQAVEAAQEMLLDNKFGDSGARVVIEEFLDGEEFSLFAFVNGDKFYIMPTAQDHKRAF
                     DGDKGPNTGGMGAYAPVPHLPQSMVDTAVETIVRPVLEGMVAEGRPYLGVLYVGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNIDDIMMGIEPYITWQKDGVTLGVVVA
                     SEGYPLDYEKGVPLPEKTDGDIITYYAGAKFVENSELLLSNGGRVYMLVTTEDSVKAG
                     QDKIYTQLAQQDTTGLFYRNDIGSKAIRE"
     gene            12749..13240
                     /gene="purE"
                     /locus_tag="VCR92_001440"
     CDS             12749..13240
                     /gene="purE"
                     /locus_tag="VCR92_001440"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001875905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEP4268501.1"
                     /translation="MKTPIISIIMGSKSDWATMQKTAEVLDNFGIAYEKKVVSAHRTP
                     DLMFKHAEEARGRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYS
                     IVQMPGGVPVATMAIGEAGATNAALTALRILSIEDQNLADALAHFHEEQGKIAEESSG
                     ELI"
     gene            13227..14300
                     /gene="purK"
                     /locus_tag="VCR92_001441"
     CDS             13227..14300
                     /gene="purK"
                     /locus_tag="VCR92_001441"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEP4268502.1"
                     /translation="MNSFKTIGIIGGGQLGQMMAIAAIYMGYKVITLDPASDCPASRV
                     SEVIVAPYDDVEALGQLAARCDVLTYEFENIDADGLDAVVSACQLPQGTDLLRISQNR
                     IFEKDFLANKAGVTVAPYKVVTSSLDLGGLDFTKTYVLKTATGGYDGHGQKVIRSAED
                     LPEAQQLANSAQCVLEEFVNFDLEISVIVSGNGEDVTVFPVQENIHCNNILSKTIVPA
                     RISDQLADKAKKMAVQIAKKLQLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPTIHLHAPAVMLNVLGQHVQQAIDYVAQNPSAHLHMYGKLE
                     AKHNRKMGHVTVFSDLPDEVEEF"
     gene            14302..15720
                     /locus_tag="VCR92_001442"
     CDS             14302..15720
                     /locus_tag="VCR92_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268503.1"
                     /translation="MYLKYIFKIKDRNLVSDYESLVRNLTINLQKLVIKDRTALIGDK
                     QLPITIYYRGENEKFPTGIVKVESDSVEGLELFDKTIKEIVGNESRFGKFTCIYDGIS
                     TYYSTEIYSELHEIERRTQEFLREAFFLSDKSGELKEYQATIKKMDSSDFSFSKLINE
                     IFKASDITDTFIDHVRACVEFGTVPNGDLLPKSFWDSLDDSLLDDKEQGLEINNLLNE
                     IRSTRNTIAHCKEFKKKDYINCIEQVKKLKQALDKIIASIESTDISKMSREVSRINNS
                     LQADNDYIKQKYFIEYDIFEKDILARTGLLEIDWENVSDDIEPLKIHRNFYESISEKT
                     DSEVIEEIKNLEDINFTDEKGNDLDDLTIIVPAQDEGFKRVFLGQREWYDIRIGKSKR
                     NRIKYIAGYEVAPESGVKYWAEVDKIVPSDNYVGYWKVIFKGEVKEYSEYKRLGNTWP
                     PQNSRYVSKKALDEAKYLSDVF"
     gene            15740..17032
                     /gene="purB"
                     /locus_tag="VCR92_001443"
     CDS             15740..17032
                     /gene="purB"
                     /locus_tag="VCR92_001443"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEP4268504.1"
                     /translation="MIERYSRPEMAAIWTEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIREKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVADKAREHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVSLWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMMRNMESTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPL
                     LEEDTKVTSCLTQEELDELFNPIYYTKRVDDIFKRLGI"
     gene            17163..>17717
                     /gene="rgg4"
                     /locus_tag="VCR92_001444"
     CDS             17163..>17717
                     /gene="rgg4"
                     /locus_tag="VCR92_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Rgg4/ComR"
                     /protein_id="HEP4268505.1"
                     /translation="MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSI
                     PSLSKVIFIAKALNVSVGYLTDGADLELPKRYKELKYLILRTPTYMDDGKLQVREEQF
                     DEIFEDYYDKLPEEEKIIIDCLQATLDTLLSENTNFGIDLLQEYFNQIKTKVRFRQND
                     LILLELYLAYLDIEGMDGQYSDKIF"
BASE COUNT         5237 a         3328 c         4104 g         5048 t
ORIGIN      
        1 ccttttttta aaaaaactta taaacgtaaa taatatcttg aatattttta tagagtatgt
       61 tactcttaaa tgaaaacaga aagaaaggcg aataatcaag tgactaacca gcttatttat
      121 aaaggaaaag cgaaagatat ttatagtaca aaagatgaaa atgtgattag aacggtctat
      181 aaagaccaag ctactatgtt gaatggagct cgtaaggaga ctattgatgg caagggagca
      241 ctaaataatc agatttcatc tcttattttt gagaaattaa ataaggctgg tgtggtgaca
      301 cattatattg agcaaatttc aaaaaacgaa caattgaata aaaaagttga tattattcca
      361 cttgaggtgg tgttacggaa tgtgatagca ggctcatttt caaaacgttt tggagtggaa
      421 gaaggacgtg ttcttgaaac gccaattgtg gaattttact acaaaaatga tgatctgaat
      481 gatcctttta tcaatgatga gcatgtgaag tttttgggta ttgttaatga tgaggagatt
      541 gcttatctga aaggagagac tcgccgtatt aatgaactct tgaaaggttg gtttgctcag
      601 attgggctta acttgattga cttcaagttg gagttcggat ttgatcaaga aggtacaatt
      661 atcttagcag atgaattttc gcctgataac tgtcgcctat gggataagaa tggtaaccat
      721 atggacaagg atgtttttag aagagacctt ggcaacctga cggatgtcta tcaagttgta
      781 cttgagaagt tgatagcatt gtaactagaa gaggaaggaa ttgaatccgt tcgggaaact
      841 ccgaaaaaaa gatggaactt actgaaatct caatttcaga tgtcctccta ttttccagtc
      901 gctcccttgt cggacttggt atcttatatg aataaacgta tttttgttga gaaaaaggct
      961 gactttggta ttaaatcggc tagccttgtg aaagagttga cgcataatct acaactgact
     1021 tctttgaagg ctttgcgtat tgtgcaggtc tatgatgtct tcaatttggc tgaggatttg
     1081 ctggcgcgtg ctgagaagca tattttctct gagcaggtga cagactgtct tttgacggaa
     1141 actgaaatca ctgcggagct tgataaggtt gccttctttg ccattgagtc gcttcctggt
     1201 caatttgacc aacgtgctgt tagttcgcaa gaagctttgc tattatttgg aagtgacagt
     1261 caggttaagg tcaatacagc ccagctttac ttggtcaata aggatattgc agaagcagag
     1321 cttgaagccg ttaagaacta tcttttgaac cctgttgatt cgcgtttcaa ggacattact
     1381 ttgccgcttg aagagcaggc tttctctgtg tctgataaga cgatccctaa tcttgatttc
     1441 ttcgagactt ataaggctga cgattttacg gcttataagg tagagcaggg cttggctatg
     1501 gaggtcgatg atcttctctt catccaagat tatttcaaat caatcgggcg tgtgccaact
     1561 gagactgagt tgaaagtttt ggatacgtat tggtcagacc actgtcgtca cacaaccttt
     1621 gaaactgaat tgaagaacat tgatttttca gcttctaaat tccaaaaaca attgcagaca
     1681 acttatgaca aatatatcgc catgcgtgat gagcttggtc gttctgaaaa gccacaaaca
     1741 cttatggata tggcgactat ttttggtcgt tatgagcgtg ccaacggtcg tctggacgat
     1801 atggaagtct cagatgaaat caatgcctgc tcagttgaga ttgaagtaga tgttgatggt
     1861 gtgaaagagc cttggctcct catgtttaag aatgagacac acaatcaccc aacagaaatt
     1921 gagccattcg gtggagcggc gacttgtatc ggtggtgcta ttcgtgaccc attgtcagga
     1981 cgttcatacg tttatcaggc tatgcgtatt tcaggcgcag gcgatatcac gactccgatt
     2041 gcggaaacac gtgctggtaa attgccacaa caggttattt ctaagactgc ggcgcacggc
     2101 tattcttcat atggtaacca aattggactt gcgacaactt atgtgcgtga gtacttccac
     2161 cctggcttcg tagccaaacg tatggagctt ggagctgtgg ttggtgctgc acctaaggaa
     2221 aatgtggttc gtgaaaaacc agaagcaggt gatgtggtaa tcttgcttgg tggtaaaaca
     2281 gggcgtgacg gtgtcggcgg tgcgacaggt tcatctaagg ttcaaacggt tgaatctgtg
     2341 gaaacagcag gagcagaggt acaaaaaggg aatgccatcg aagagcgtaa gattcaacgt
     2401 cttttccgtg ctggcaatgt cactcgtctg atcaagaaat caaatgactt cggtgcaggt
     2461 ggtgtctgtg ttgccatcgg tgaattggct gacggtcttg aaatcgattt ggacaaggtg
     2521 cctcttaaat accaaggtct taatggtact gaaattgcaa tctcagaatc tcaagagcgt
     2581 atgtcagtcg ttgttcgtcc aagtgatgtg gatgccttca tcgcagcctg caacaaggaa
     2641 aatatcgatg cagtcgtagt tgcgactgtg actgaaaaac caaatcttgt catgacttgg
     2701 aatgatgaaa caattgttga tttggaacgc cgtttccttg ataccaatgg tgtccgtgtc
     2761 gttgttgatg ctaaagtcgt tgacaaggac ttgacagttc cagaagcacg cataacatca
     2821 gcagagacac ttgaagcaga tacgcttaag gtcttgtctg acctcaacca tgctagtcaa
     2881 aaaggtctcc aaaccatctt tgactcatct gttggtcgtt caaccgttaa ccacccaatc
     2941 ggtggtcgtt accaaatcac accgacagaa agttctgttc aaaaattgcc agttcaacat
     3001 ggtgtgacaa caactgcatc tgttatggct caaggttaca atgcttatat tgcagagtgg
     3061 tcaccttatc acggtgctgc ctatgctgtt attgaagcga cagctcgctt ggtagcaaca
     3121 ggtgctgact ggtctcgtgc acgtttctct taccaagagt atttcgagcg tatggataaa
     3181 caggcagagc gttttggtca gccagtatca gctcttcttg gttctattga ggctcagatt
     3241 caacttggct tgccatcaat cggtggtaag gactctatgt ctggtacttt cgaagacttg
     3301 acagtaccac caaccttggt agctttcggt gtgacaacag cggacagccg caagattctc
     3361 tctcctgagt ttaaagcggc tggtgagaat atctactaca ttccaggtca agctatttca
     3421 gaagatattg attttgacct tatcaaggct aacttcagtc agtttgaagc tattcaaact
     3481 caacataaga ttacagctgc ctcagccgtt aaatacggtg gtgtcctaga aagttttgct
     3541 ctcatgactt ttggtaaccg tatcggtgct tctgttgaaa ttgcagagct tgacagcagc
     3601 ttgacagctc aactcggagg ttttgtcttt acatcagctg aggaaattgc tgacgcggtg
     3661 aaaattggtc aaactcaggc agactttaca gtcactgtca atggaaatga ccttgctggc
     3721 gctagccttc tagcagcctt cgaaggcaaa ttggaagagg tttacccaac agaatttgaa
     3781 cagacagatg ttcttgaaga agttcctgct gtggtatcag atactgttat caaggctaag
     3841 gaaacaattg aaaaaccagt ggtttacatt ccagtcttcc ctggtaccaa ctcagagtac
     3901 gattcagcta aggcctttga acaggttgga gctagtgtca acttggtacc atttgtaacc
     3961 ttgaatgagg ttgctattgc tgagtcagtt gacactatgg ttgctaatat tgctaaggca
     4021 aatatcatct tctttgctgg aggtttctca gcagcggatg aaccagatgg gtctgctaag
     4081 tttatcgtca atatcttgct taacgagaag gtccgcgcag ctattgacag cttcatcgaa
     4141 aaaggtggcc ttatcatcgg tatctgtaat ggtttccaag cccttgttaa atcaggtctt
     4201 cttccatacg gaaacttcga ggaagctggt gagacaagtc caactctctt ctataacgat
     4261 gctaatcagc atgttgccaa gatggttgag actcgtatcg caaataccaa ctcaccttgg
     4321 ttggcaggag ttgaggtcgg cgatattcat gccattccag tttcacatgg tgaaggtaaa
     4381 tttgttgtca gcgcttctga atttgcagag ctaagagaca atggtcaaat ctggagccaa
     4441 tatgtggact ttgacggaca accatctatg gattctaaat acaatccaaa cggctctgtc
     4501 aatgccatcg aagggattac cagcaagaat ggtcaaatca tcggtaagat gggacactca
     4561 gaacgctggg aagacggact cttccaaaat attcctggta acaaagacca aaccctcttt
     4621 gcaagtgctg taaaatactt tacagggaag taaaaaggtt cagtgaacct ttttagccct
     4681 cgccttgaat tagtgaaggg caaggttaga aagaatctcg cttaattttt gagaaatagt
     4741 aaacacgggc gataagttgt gcgaaaaact ttctattttc gctttacttg acagcctttg
     4801 tatcgaggta aaaatgacat acgaagtaaa atctctaaat gaagaatgtg gagtctttgg
     4861 tatctgggga catcctcagg cagctcaagt cacttacttt gggcttcata gccttcaaca
     4921 tcgcggtcaa gaaggagctg gtattgtttc aaatgacaat gggaaactct atggttatcg
     4981 aaatgttggg ctcctttctg aagtttttaa gaatcaatct gaattagata atttaactgg
     5041 gaatgcggct attggacatg ttcggtatgc tactgcaggt tctgcagata ttcgcaatat
     5101 tcagcctttt ctttataaat ttcatgacgg gcaatttgct ttatgccata atggtaattt
     5161 gacaaatgct atttccttaa ggaaagaatt agaaaagcaa ggtgcaattt tcaatgcctc
     5221 ctcagatact gaaattttga tgcacttgat tcgtcgaagc cataactcaa gtttcatggg
     5281 aaaggtaaaa gaagctctaa atacagtaaa gggtggcttt gcctatctac tgatgacaga
     5341 aaataaactc attgctgctc ttgaccctaa tgcctttcgt cctttgtcaa ttggacaaat
     5401 gcaaaatggt gcctgggtta tttccagtga gacctgtgct tttgaggtgg taggcgcaaa
     5461 atgggttaga gatgttgaac ctggcgaagt tattcttata gacgatcgtg gtattcaatg
     5521 tgatcgttat actgatgaaa cgcaactggc aatttgttcg atggaatatg tctattttgc
     5581 aaggccggat tcaactatac atggtgttaa tgttcatacg gctcgaaaaa atatgggaaa
     5641 gcgtcttgca caagaattta aacaggatgc tgatattgta attggtgtcc caaattcgtc
     5701 cttatcggct gctatgggct ttgctgaaga atccggatta ccaaatgaga tgggtcttgt
     5761 aaaaaatcag tatacgcagc gaacctttat tcaaccgaca caagaattaa gggaacaagg
     5821 tgttcgaatg aaactatcag cggtatctgg tgttgtcaaa ggaaagcgcg ttgttatgat
     5881 tgatgactca attgtaagag gaacgacttc tagaaggatt gtcggattat taagagaagc
     5941 aggagctagt gaagtacatg ttgctatagc tagtccagaa ttaaagtatc cttgttttta
     6001 tggtattgat attcaaacaa gacgagaatt aatttcagca aatcacgctg ctgacgaagt
     6061 gtgtgatatt attggcgcag atagtctgac ctatctctca ctagatgggt tgattgaatc
     6121 aattggactc gaaacaaaag caccaaatgg tggtttatgc gtagcttact ttgatggaca
     6181 ttatccaaca ccgctttatg attatgaaga agaatacctc agaagtttag aagaaaaaac
     6241 aagtttttat attcaaaaag tgaaataagc tctgctaatt atataaggag aaaacatgtc
     6301 tgaaaaaaat gcttatgcaa aatctggtgt tgatgttgaa gctggttatg aagtggttga
     6361 aagaataaaa aaacacgttg ctcgtacaga acgtgcggga gtcatgggag ctctaggtgg
     6421 ctttggtggg atgtttgact tgagtaaaac aggagttaga gagcctgttt tggtctcagg
     6481 gacagacggt gttggcacaa aactcatgct tgctatcaag tacgacaagc acgacacaat
     6541 cggtcaagac tgtgttgcca tgtgtgtcaa tgatattatt gcagcaggtg ctgagcccct
     6601 ttacttcctt gactacgtag cgacaggaaa aaataatcca gtcaaatttg aagaagttgt
     6661 ttctggcgtt gcagaaggtt gtgttcaagc aggagcagca ctcattggag gtgagaccgc
     6721 tgaaatgcct gggatgtatg gcgaagatga ttatgacctt gctggctttg ctgttggtgt
     6781 ggctgaaaaa tctcagctca tcgacggttc aaaagtaaag gaaggcgata ttcttttggg
     6841 acttgcttca agtggtatcc attcaaacgg ttattctttg gtacgtcgtg tctttgctga
     6901 ctatactggt aaagagctgc ttccagaact tgaaggaaaa caacttaagg atgtccttct
     6961 tgagccaact cgtatttatg ttagagcagc tctgccatta atcaaggaag aactaatcaa
     7021 cggtatcggc cacatcacag gtggtggctt tatcgagaat gttcctcgta tgtttgcaga
     7081 tgatttggct gcggaaatcg atgaggacaa ggtgccagtg cttccgattt tcaaggcgct
     7141 tgaaaaatat ggtgacatca agcacgaaga aatgtttgaa atcttcaata tgggtgtcgg
     7201 tcttatgcta gctgttagtc ctgaaaatgt taaccgcgtc aaagagctct tggatgaacc
     7261 agtttatgaa atcggtcgta tcatcaagaa agcagacgat agtgtggtga ttaaataagt
     7321 cactaaattt tataagaaag gagtgtttag ttagtttgcc taactgaaca cgggattaaa
     7381 tttctaggaa aaaagataaa atgacttaga cgcaagcgtc gttgttcgtt ttcctatttt
     7441 tctacgaaat ttttcggcaa gccgaatcat ccctttgtat cgaatatgaa aatcgctgtt
     7501 tttgcttctg gtaatggttc caactttcag gtcatagcag agcagtttcc agttagtttt
     7561 gtcttttcag atcatcgtga tgcctatgtt ttagagcgtg ctcagaattt agccattcca
     7621 agcttcgctt ttgaactcaa ggagtttgag aataaggcgg cttacgagca agccatcgtt
     7681 gatttgttgg acaaacacga gattgatttg gtctgtctaa cgggctatat gaagattgtt
     7741 ggagaaacct tactcttggc ctatgagggg cgtattatca atattcaccc agcctacctg
     7801 cctgaatttc caggtgccca cggtatcgag gatgcttggg aagctggtgt tgaccagtct
     7861 ggcgtgacca tccactgggt tgactctggt gtggataccg gtcaggtcat ccaacaagtg
     7921 cgcgtgccac gcctagcaga cgatagccta gaaagctttg aaacccgtat ccatgaaacc
     7981 gaatatcaac tctacccagc tgtcttagat agcttgggag tggagaggaa agtaatctag
     8041 cctttatctt aaaattttag gtaaagttag gaaagatagt aaagaagaat taacgttcca
     8101 aaaagaaagg aattgaaccc gtctggaagg cacagaaaaa agataaacat ctcctaggcg
     8161 caagcgtctt cgtcgagttt cctatttttc cttggccttc tagtcggact tggtatctta
     8221 aatatgacta aacgtgcttt aatctcagtg tctgacaagt caggaattgt tgactttgca
     8281 aaagaattga aaaacttggg ttgggatatt atctcaactg gtgggactaa ggttgccctt
     8341 gataatgctg gcgttgagac cattgccatc gacgatgtga ctggattccc agagatgatg
     8401 gacggtcgtg ttaagaccct ccacccaaac attcacggtg ggcttttggc tcgtcgcgac
     8461 gctgacagcc accttcaggc tgctaaggac aacaatatcg agctgattga cctcgtggtt
     8521 gtcaacctct atcccttcaa ggagactatc cttcgtccag atataaccta tgatttggcg
     8581 gtggaaaaca tcgacatcgg cggtccatca atgcttcgct cagccgctaa aaatcacgct
     8641 agcgtgaccg ttgtggttga cccagcggat tatgcgactg ttttgggaga attggctgac
     8701 gctggtcaga cgacatttga aacgcgtcaa cgcttggcag ctaaggtctt tcgtcacaca
     8761 gcagcctacg acgctttgat tgctgagtac ttcacaactc aagtgggaga ggctaagcct
     8821 gaaaaattaa ccatcactta cgaccttaaa caggctatgc gttacggaga aaatccacaa
     8881 caagacgctg atttctatca aaaagccttg ccaacagact actcaattgc ttctgctaaa
     8941 cagctcaacg gaaaagaatt gtccttcaat aatatccgtg atgccgatgc agcaatccgt
     9001 attatccgtg atttcaaaga tcgtccaact gttgttgtcc tcaaacacat gaacccatgt
     9061 ggtatcggac aggctgatga tattgagaca gcttgggatt acgcttatga agctgaccca
     9121 gtttcaatct ttggtggaat tgtcgtcctt aaccgtgaag ttgacgcagc gacagctaag
     9181 aagatgcacc ctatcttctt ggaaatcatc atcgcaccat catactcaga agaagcgcta
     9241 gctattctca caaataaaaa gaaaaacttg cgaatccttg agttgccgtt tgatgcccaa
     9301 gctgccagcg aagtggaagc tgagtacact ggcgtagttg gtggactttt ggtgcaaaac
     9361 caagacgttg tggctgaaaa tccatctgac tggcaagtgg tgacagaccg ccaaccaaca
     9421 gaacaagagg cgactgccct tgagtttgcc tggaaggcta tcaagtatgt taagtctaac
     9481 gggattatta ttactaacga tcacatgacg cttggactcg gtgcaggtca aaccaaccgt
     9541 gtcggctcag tcaagattgc tatcgagcag gctaaagacc accttgacgg tgccgttcta
     9601 gcatcagatg ccttcttccc atttgcggac aacattgaag aaatcgctgc cgcagggatc
     9661 aaagcaatca tccaaccagg tggttcagtt cgtgaccaag actctattga cgccgcaaac
     9721 aaacatggct tgaccatgat cttcacaggt gtgagacatt ttaggcatta ataaaaaaat
     9781 gtggtctaat taaaaccaca ttttttatta aaagaaaata taagttaact ataatttgtt
     9841 agctttatca gcatttaccc atgttccacg agatccgatt tgaacataaa taccattact
     9901 tggttgatca atttttaata ctttataact accagtgacg gtaaaatatt cacccacacg
     9961 gagaatttga tctcctaaaa cttttccttg gttatctgtt tcatctaatg gtgtgggatc
    10021 aatccagttt agtggagttg ggtctcctcc ggctaattct ttattaacga tcaaattatt
    10081 aacaagctga tctacacgaa aaacgccagg gaaggtaaca gtatcaccga ccttaatgga
    10141 aggttttgta ttgtcatttt gaaccacaga ctgtgcgggc tctttaatgg gaatatagcg
    10201 tcggtttcca gaaaaactga ggtagctaag ccatgtataa cctccagcag tcacgacttt
    10261 atcgtaataa acagattgac ctgcttcata gtaagcaaga tcagggctat cgatactggt
    10321 ttgtcctttg actggtaatc tggttgtaaa gtgataagtt ccagaggggt caaatgaagc
    10381 ttgagaaatg tgttttagtt gtcttgggta ggaatgactt gtctgagatg ataagtcttt
    10441 aaaatggata taaccactta cctgagattt tggaatttga cgcttatggt atctttcagg
    10501 gccttgtcca gcgttgtaat tatactcttc gatagtgaca gtgtctccac ggatatcagc
    10561 tacccatgct acatgaccgt aagcagcatt tgactgataa gcgtttttat caaaccaagc
    10621 gatagcccct atgcttggtg tcttattcac aggataaccc tgatttttcg cgatatgtcc
    10681 ccacgtgcag gcattaccgt agcctttagg taactgaaaa ccattagcag agcttaaacg
    10741 aaaagctgca aaagaagtgc attggcggat atacatgttc cacgaatcga ttccattgcc
    10801 ttttttccac ttactcggat agttatcgcc taaaacagct gcatgaacaa gattttcctg
    10861 ttgcgaaata agtgtagatg gcatagtagg tactagacca ttaaaaccta aaaggattac
    10921 tcctgagacc aaaaaacgat gaaatttttt cattaattac ctcctgtaac ttattattcg
    10981 aaagcaagaa acaaaaaatg ttatttttag atgattattt tgaaaattgg ctttacttga
    11041 tattaaataa ctgtttgatt ggctaataga gtgttcctta tttcaagaat tgtggtctac
    11101 tatcacattt ttacaatgtt tcaattattg ataactaata cattatgtaa aaaagcgaac
    11161 gtttatgata taatatctaa ttataatacg aaagaggtgg atgttttgaa attacttgtt
    11221 gttggttcag gtggtcgtga acatgcgatt gctaagaagt tgttagcgtc taagggtgtg
    11281 gatcaggttt ttgtggcacc tggtaatgat ggtatgacct tggatggtct ggacttggtg
    11341 aatatagtag tttccgaaca ttccaggttg attgcctttg ctaaggagaa tgagatttct
    11401 tgggccttta ttggtcctga tgatgcgcta gcagctggta tcgttgatga tttcaacagt
    11461 gctggactca gagctttcgg tccaacaaag gcagcagcgg agctagagtg gtcaaaagac
    11521 tttgccaagg aaatcatggt caaatacaat gtcccaacag cagcctatgg cacattttca
    11581 gactttgaaa aagccaaagc ctacatcgaa gagcagggcg tacctatcgt ggtcaaggct
    11641 gatggcttgg cgctaggtaa gggtgtggtc gtggctgaaa ccgttgagca ggcggtagag
    11701 gcggcgcaag agatgcttct ggacaataag tttggcgatt caggagcgcg tgtggttatc
    11761 gaggaattct tggatggcga ggagttttcc ctctttgcct ttgttaatgg tgataagttc
    11821 tacatcatgc cgacagctca ggatcacaag cgtgcctttg acggagacaa ggggccaaac
    11881 actggtggta tgggtgccta tgcgccagtt cctcatctac ctcagagcat ggtagacaca
    11941 gcggttgaga cgatcgttag gcctgtcctt gagggcatgg ttgccgaagg gcgtccttat
    12001 ctaggtgtcc tctatgtggg gcttatcctg acagctgatg gacctaaggt tatcgagttc
    12061 aactcacgtt tcggtgaccc tgaaactcag attatcctcc ctcgcctgac ttccgatttc
    12121 gctcagaata ttgacgatat catgatgggc attgagcctt acatcacttg gcagaaggac
    12181 ggtgtgactt tgggtgttgt cgttgcctca gaaggctatc cactcgatta tgagaaaggt
    12241 gtgccactgc ctgaaaagac cgacggcgat atcatcacct actatgccgg agctaagttt
    12301 gtggaaaata gcgagctact tctctcaaac ggaggacgtg tctatatgct tgtcaccaca
    12361 gaagacagcg tcaaagcagg gcaggacaaa atctataccc agctagccca acaagacaca
    12421 acaggtctct tctaccgaaa tgacatcgga agcaaagcta taagagaata agactaacca
    12481 ttcaaatatt agcgtcagca atcaacgacc gaaggtcgct ccaaaaagaa agaagaaagg
    12541 aactgaacac gggactaatt tcctaggaaa aaaataaaac tacctggaca caagcgtcat
    12601 cgttagtttt ctgcgtcgta ggcgtctgat gctaaagcac ctagtcgccc tgacgtgggt
    12661 tcgtcttcga aatcaaagat ttcggactta ccgcatattt ttctacggaa attttcgaca
    12721 agtcgaaacg cccctttgta tcttaattat gaaaactcca attatttcta ttatcatggg
    12781 ctccaaatct gactgggcaa ccatgcaaaa aacggctgaa gttctagaca actttggcat
    12841 tgcttacgag aagaaagtcg tctctgccca ccgtacgcca gacctcatgt tcaagcatgc
    12901 tgaggaagca cgtggtcgtg gcatcaaaat catcatcgca ggagcaggtg gggcagctca
    12961 cttgcctggt atggtggcag ctaaaacaac cctgcctgtt atcggtgtgc ctgtcaaatc
    13021 acgtgccctt tcaggtttgg attcactcta ttcgattgtg cagatgcctg gcggtgtgcc
    13081 tgtggcaacc atggctatcg gagaagcggg agcgactaac gctgccctga cagccctccg
    13141 tattctctcc atcgaggatc aaaatctggc tgatgcgcta gctcatttcc atgaggaaca
    13201 aggaaaaatc gcagaggagt caagtggtga actcatttaa gaccattggg attatcggtg
    13261 gtggtcagct ggggcagatg atggccattg cggctatcta tatgggctac aaggtcatca
    13321 cgctggatcc tgctagcgac tgccctgcct cccgcgttag cgaggtaatt gtggcgcctt
    13381 acgatgatgt tgaggctttg ggacaattgg ctgcgcgttg cgatgtattg acttatgagt
    13441 ttgagaatat tgatgcggac ggtttggatg ccgttgtgtc agcttgtcag ctaccgcagg
    13501 ggaccgatct gctccgcatt tcccaaaacc gtatctttga aaaagacttt ctggcaaata
    13561 aggctggtgt gactgttgct ccctataagg tggtgacgtc tagccttgac ctagggggac
    13621 ttgattttac caagacctat gtcctcaaga cagcgacagg tggttatgac ggtcatgggc
    13681 aaaaggttat ccgctcagca gaagatttgc cagaggcgca gcaattagct aactcagctc
    13741 agtgtgtctt ggaagagttt gtcaactttg accttgaaat ctcagtcatc gtgtctggaa
    13801 atggagagga tgtgacggtc tttcccgttc aggaaaatat ccactgcaac aatatcctgt
    13861 caaaaactat cgtgccagct cgtatctcag atcaactggc tgataaggct aagaaaatgg
    13921 cggtgcagat tgccaagaaa ctccagctgt caggaactct ctgtgtggaa atgtttgcga
    13981 ccgcagatga tatcattgtc aatgaaattg ccccacgtcc ccacaactca gggcactact
    14041 caatcgaggc ttgcgacttt tcacagtttg acacccacat tttgggcgtg ctaggagcgc
    14101 cgctcccaac catccacctc catgctccag ccgtcatgct caatgtcctc ggacaacacg
    14161 tccagcaggc aattgactat gttgcccaaa accctagcgc ccacctccac atgtatggta
    14221 aactagaagc gaaacataac cgcaaaatgg gacatgtgac ggtgtttagt gatttgcctg
    14281 atgaggtgga ggagttttag gatgtatcta aagtatatat ttaaaataaa ggataggaat
    14341 ttagtatcgg attatgaatc tttagttcga aatttgacaa tcaatcttca aaaactagtt
    14401 attaaagata gaactgcatt aataggggat aaacaacttc caattacgat atattatcgt
    14461 ggggagaatg aaaagtttcc tacgggaata gtaaaagttg aatcagactc agttgaagga
    14521 ttagagttat ttgataaaac gataaaggaa atagttggga atgaaagtag atttggaaag
    14581 ttcacatgta tatacgatgg aataagtaca tattattcaa cagaaattta ttctgaactt
    14641 catgaaattg agcgtcgaac acaagagttt ttaagggaag cattttttct gagcgataaa
    14701 agtggggaat tgaaagaata tcaggcaact atcaaaaaaa tggatagtag tgatttctca
    14761 ttcagcaaat taattaatga aatttttaaa gcaagcgata taactgatac atttattgac
    14821 catgttagag cgtgtgttga atttggaaca gttccaaatg gagatttatt accaaaaagt
    14881 ttttgggata gtttagatga ctctttacta gatgataaag agcaaggttt agagattaat
    14941 aatttattaa atgagattcg ttcaacaaga aatacaatag ctcactgtaa agagtttaaa
    15001 aagaaggatt atattaattg tatagaacaa gttaaaaaat taaagcaagc attggataaa
    15061 ataatagcct ctatagagtc tacagatatt tctaaaatgt cacgagaagt gtcacgcata
    15121 aataactcct tacaagccga taatgactac atcaaacaaa aatattttat agaatatgat
    15181 atttttgaaa aggatatatt agctaggaca gggttattag aaattgattg ggaaaacgtt
    15241 tctgatgaca tagagccctt aaagatacat cgtaactttt atgaatcaat tagtgaaaaa
    15301 acagattctg aagttataga agaaatcaaa aatttagaag atataaattt cactgatgaa
    15361 aagggtaatg atttggatga cttaaccatt attgttcctg cgcaagacga aggatttaaa
    15421 agagtctttc taggtcaacg agaatggtat gatatacgga taggaaaatc gaaaaggaat
    15481 aggattaaat atatcgcagg atatgaagtt gcaccagaga gtggtgtaaa gtactgggct
    15541 gaagtggata aaatagttcc ttcagataac tatgttggtt actggaaagt aatttttaaa
    15601 ggagaggtga aggaatattc agaatataaa agattaggaa atacttggcc ccctcaaaac
    15661 agtagatacg tatctaaaaa ggctttagat gaagctaaat atttatcgga tgttttttaa
    15721 ttaaaggaga aaaaacaaaa tgatcgaacg ttattcacgc cctgagatgg cggcaatttg
    15781 gacagaggaa aataaatacc gtgcttggtt ggaggttgag attctggctg acgaggcatg
    15841 ggcagagttg ggtgagattc ctaaggagga tgtggctaag attcgtgaga aggcggattt
    15901 tgacattgac cgcattcttg agattgagca ggagacgcgt cacgatgtgg tggctttcac
    15961 gcgtgcggtt tctgaaacgc ttggtgagga gcgcaagtgg gtgcactacg gtttgacctc
    16021 gactgacgtg gtggacactg cctacggtta cctctacaag caagctaacg acattatccg
    16081 tcgcgatctt gagaatttca ccaatatcgt ggcagacaag gcgcgtgagc acaaaatgac
    16141 catcatgatg ggtcgtaccc acggtgttca cgccgagcca acgactttcg gtcttaagtt
    16201 ggcgacttgg tacagcgaga tgaaacgtaa tattgagcgt tttgaacatg ctgctgcagg
    16261 tgtggaagct ggtaagattt caggtgccgt tggtaacttt gccaacatcc caccttttgt
    16321 ggaagaatat gtctgtgaca aattaggcat tcgtccgcaa gaaatttcaa cacaagttct
    16381 tccacgtgac cttcacgcag aatactttgc agtgcttgca agtattgcaa cttctatcga
    16441 acgtatggcg acagagattc gtggtctgca aaaatcagaa caacgtgaag ttgaagagtt
    16501 ctttgccaaa ggtcagaaag gtagctctgc tatgcctcac aaacgcaacc caatcggttc
    16561 agagaacatg acagggctag cgcgcgtgat tcgtggtcac atggtgacag cttatgagaa
    16621 cgtgtcactt tggcatgagc gtgatatttc acactcatca gctgagcgta tcatcacacc
    16681 tgacacaact atcttgattg actacatgct caaccgcttt ggcaatatcg ttaagaactt
    16741 gactgtcttc ccggaaaata tgatgcgcaa tatggaatca acttttggtt taatttatag
    16801 tcaacgtgtt atgctcaaat tgattgaaaa aggaatgaca cgagaagaag cttatgactt
    16861 agttcaacct aagacagctt attcctggga caatcaagtg gatttcaaac cacttttaga
    16921 agaagacacc aaagttacct cttgtcttac acaagaagaa cttgatgaac tatttaatcc
    16981 gatttattac acaaaacgtg ttgatgatat ttttaagcgt ttagggattt aatataaaaa
    17041 aaagaaggtg attcccttct tttttattta aaaaacgaat attttcttta aaaatattaa
    17101 aaatgttagt ttttaattag acgctgtgat ataataaaga aaacagttgt tggagagaaa
    17161 ccatgttaga acattttggt ggaaaagtaa aagtgttaag acttgaaaag aggattagtc
    17221 gcgaggactt gtgtggggat gagtctgaac tttctgttcg tcaattagca cggatagaac
    17281 taggtcaatc cataccaagt ttaagtaagg ttatttttat tgcaaaagcc ttaaacgtta
    17341 gtgtcggtta cttaactgat ggtgctgatt tagaactacc taagcgttac aaagaattaa
    17401 aataccttat cttaaggaca ccaacttaca tggatgatgg aaaattacaa gtacgagaag
    17461 agcagtttga tgaaattttt gaggattatt atgataaatt accagaggaa gagaaaataa
    17521 tcattgattg tttacaggca actttagata ctttattgag tgagaatact aactttggca
    17581 ttgacttact tcaagaatat tttaatcaaa taaagactaa ggtacgcttt aggcaaaatg
    17641 atttaatact tctagaatta tatttagctt atcttgatat tgagggaatg gatggacaat
    17701 attcagataa gattttt
//
LOCUS       DATWEK010000035        14986 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.035, whole genome shotgun sequence.
ACCESSION   DATWEK010000035 DATWEK010000000
VERSION     DATWEK010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14986
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.035"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            15..203
                     /locus_tag="VCR92_001445"
     CDS             15..203
                     /locus_tag="VCR92_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEP4268506.1"
                     /translation="MLTYDEFKQAIDNGYITGDTVIIVRKNGQIFDYVLPGEKVRPWE
                     VVTEEVVEEVMVELDYIK"
     gene            complement(355..702)
                     /gene="ssrA"
                     /locus_tag="VCR92_001446"
     tmRNA           complement(355..702)
                     /gene="ssrA"
                     /locus_tag="VCR92_001446"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            794..1408
                     /locus_tag="VCR92_001447"
     CDS             794..1408
                     /locus_tag="VCR92_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEP4268507.1"
                     /translation="MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSN
                     ALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIII
                     GSIVLFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVM
                     ITGLTDMSLKRFVTILLITKPISIIGYSYLFIFGKDVISWFLQH"
     gene            complement(1535..2320)
                     /locus_tag="VCR92_001448"
     CDS             complement(1535..2320)
                     /locus_tag="VCR92_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4268508.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSD
                     GLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVNSH
                     QIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKMDYFINMLTVL
                     AYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHSHIFNIN
                     TSADSFPFTEQKTIYLLILEQFIEMIMFYLATNFIIKNKLNLQ"
     gene            complement(2330..3028)
                     /locus_tag="VCR92_001449"
     CDS             complement(2330..3028)
                     /locus_tag="VCR92_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4268509.1"
                     /translation="MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKT
                     TLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFY
                     SDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDP
                     AARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEY
                     QQSIDSLFRETYKV"
     gene            complement(3028..3399)
                     /locus_tag="VCR92_001450"
     CDS             complement(3028..3399)
                     /locus_tag="VCR92_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP4268510.1"
                     /translation="MSWKFDEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTK
                     MGFSHTEIIPVLTSFLKEDSQ"
     gene            3584..6694
                     /locus_tag="VCR92_001451"
     CDS             3584..6694
                     /locus_tag="VCR92_001451"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEP4268511.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLY
                     GAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKL
                     HMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRY
                     FAQDDMETLHMLHAIRDNLSLAETPVVESDQELADCQQLTTFYQTHCPQALQNLEDLV
                     SGIYYDFDTNLKLPHFNRDKSAKQELQDLTEAGLKEKGLWKEPYQSRLLRELVIISDM
                     GFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGV
                     PEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIH
                     AAGIVMSDDTLTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEK
                     VAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVA
                     TTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQIYA
                     GFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGF
                     NRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSNYITDALESDFQVAQVTINSIP
                     YTDKIEASKIYMGLKNIKGLPRDFAYWIVEQRPFNSVEDFLTRTPEKYQKKVFLEPLI
                     KIGLFDCFEPNRKKIMDNLDGLLVFVNELGSLFSDSSFSWVDTKDYSATEKYSLEQEI
                     VGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLS
                     VNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKY
                     WLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFV
                     LKTVFR"
     gene            6774..7787
                     /gene="pfkA"
                     /locus_tag="VCR92_001452"
     CDS             6774..7787
                     /gene="pfkA"
                     /locus_tag="VCR92_001452"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEP4268512.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHI
                     IVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVEL
                     LKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRS
                     LSQ"
     gene            7850..9352
                     /gene="pyk"
                     /locus_tag="VCR92_001453"
     CDS             7850..9352
                     /gene="pyk"
                     /locus_tag="VCR92_001453"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEP4268513.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADD
                     AKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKV
                     IDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICCETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     KPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            9570..10127
                     /gene="lepB"
                     /locus_tag="VCR92_001454"
     CDS             9570..10127
                     /gene="lepB"
                     /locus_tag="VCR92_001454"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEP4268514.1"
                     /translation="MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKS
                     GDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYL
                     EKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLI
                     NASQIKGLVTFRVLPLSDFGFVEVE"
     gene            10303..12117
                     /gene="glmS"
                     /locus_tag="VCR92_001455"
     CDS             10303..12117
                     /gene="glmS"
                     /locus_tag="VCR92_001455"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEP4268515.1"
                     /translation="MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNL
                     IKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVI
                     ENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALSIIEGSYAFA
                     LMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKD
                     KVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETG
                     NVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMP
                     LLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSREATYTMLIHAG
                     PEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKD
                     LVAEKVQALLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISL
                     IEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPF
                     LAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            12313..12648
                     /locus_tag="VCR92_001456"
     CDS             12313..12648
                     /locus_tag="VCR92_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEP4268516.1"
                     /translation="MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVV
                     LDSNGVRLSDGDTITVVKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            12755..13396
                     /locus_tag="VCR92_001457"
     CDS             12755..13396
                     /locus_tag="VCR92_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEP4268517.1"
                     /translation="MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKIPF
                     KPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEI
                     FRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ"
     gene            13406..14035
                     /locus_tag="VCR92_001458"
     CDS             13406..14035
                     /locus_tag="VCR92_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEP4268518.1"
                     /translation="MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLL
                     RMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTIT
                     MGKQKSDAKEKALDLLARLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEP
                     TSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK"
     gene            14051..14887
                     /locus_tag="VCR92_001459"
     CDS             14051..14887
                     /locus_tag="VCR92_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEP4268519.1"
                     /translation="MIIKKRTVAILAIASSFFLVACQATKGLKSGDAWGVYQKQKSIT
                     VGFDNTFVPMGYKDESGKCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKID
                     VIWNGYSITKERQEKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYD
                     SLLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLEN
                     YRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQNGKFQAISEKWFGDDVATANI
                     KS"
BASE COUNT         4725 a         2452 c         3091 g         4718 t
ORIGIN      
        1 taaggaggtg ctttatgcta acatacgacg aatttaagca agcaattgac aacggatata
       61 tcacaggaga cacagtaata atcgtgcgca aaaacggaca gatttttgat tatgtgttgc
      121 ctggtgagaa agtcagacca tgggaggttg tgaccgagga ggtagtggaa gaagtgatgg
      181 tggaattaga ctatatcaaa tgaagaaaac tttgagtaga cagaaaaata attgaagagt
      241 tgtcaattta gttgtcaata atatagaaag ttatggaaac tcatgaacaa gacaaaaaga
      301 aaaaaccttg atgtaacaag gttttagtaa gttatgatta cttacggtaa gcattgatgg
      361 agctggtggg agtcgaaccc acgtccaaac acctgccaac atatttgtct acgtccatag
      421 gttatgtctt catttaacaa actaaagaca cataactcaa gccattagtt tgcgagtcta
      481 tcaatctctt gtcacgaaac tagacaattt cgtaaccgta gcttgctatt ttgagacttc
      541 taacaggaca caagcaatct tgtagaagtc acgctagctg gtttttaggc agctaaagcg
      601 taagagtttg tattttttgc agttatattt aactggcaat ttacatctgc cgatgggacg
      661 caaaacatgc ctcataatgc ctgtcgaatc cgtaacaacc ccaaatagat aattaaccaa
      721 tttcttacac taactattct atcaaaactt tttttaaata gcaaaatttt acagcttatg
      781 gtatgattag tctatgacaa aacgtaattc aaaagcctat atattatggc aaaaaattat
      841 caaaatttta ggaattattg cactaattgg tacttttttc ctcgcttttt ggctgtatag
      901 actaggtata ttaaacgata gtaatgctct taaagactta gtgcagcgct atagattatg
      961 ggggccgttt gtttttattg tcgtgcagat catacagatt gtttttcctg tgattcctgg
     1021 aggccttacg acagttgcag gttttttaat ctttggccct gtaacaggtt ttatttataa
     1081 ttatgtaggc atcattattg gcagtatagt cctcttcttg cttgttaaga cttatggtcg
     1141 taaatttatc ttactctttg taaatgacaa aacattttac aagtatgaaa ggcgtttgga
     1201 gacaccagga tatgaaaaat tatttatttt ttgtatggca tcgcctgttt ctccagctga
     1261 tattatggtt atgattacgg gattgacgga catgtcttta aagcgctttg taactattct
     1321 tttaataact aaaccaattt ctattatcgg ctacagttat ttatttattt ttggaaaaga
     1381 tgttatatct tggttcttac agcattaagg tttggtgtta atttgataaa ccgcttctat
     1441 ttgatggaag acggtttttt tatttactat gaacactgaa aaagactttc ttttaaacta
     1501 tagtgtgtca tagtttaaaa gaaagtctta acgcttactg taggttgagt ttatttttga
     1561 taataaaatt agtggcgagg taaaacatta tcatttcaat aaattgttcc aaaataagaa
     1621 gataaattgt tttttgctca gtaaatggga aactatcggc acttgtatta atattaaaga
     1681 tgtgactgtg aacatatgtt gcagcaacgc taatcagaat aactaatata aaatatgcaa
     1741 taaaggccat caagcctcgc cgattagaaa aaagttgacc tatagaaatg gaaagataaa
     1801 ttaataagat actcgtaaat gttgataata ggacataggc tagtacagtt agcatattga
     1861 tgaaataatc catcttaaaa ctattaaaga atccttctaa tagttcgttg atgttaaaca
     1921 ttggtacaat tacaatagcg atagcaaatg caaggatgat agtattgaaa acactgcaaa
     1981 taaaagaagc tagtagtttt gataaaataa tttgatgcga attaacgggt aaagtcaacg
     2041 ttaagtatcc ttcccgtcca aaaacacttt tgctaaaacg tttgataatg ataagtaatg
     2101 ttgataagag ggaaccagcg atcagggagc caaaagttaa acctaatgtc agaggtaaca
     2161 tcttattggt tagtactcca aatagtccat cactattact ttgagcaaac agttttatcg
     2221 taaatgacaa aatggcagcg atggcaataa cgaaagcatt aagcgcaaag taccattttc
     2281 caatagatct aaattcgtat tttaataatt ttccaaacat gatatcctcc taaaccttat
     2341 aagtttccct aaagagggaa tcaatggatt gctggtattc ttgtcttaga tcatcagcat
     2401 tgccagataa gaaaagtctt ccttgtttca agaaaatgac ttcgtcaagg ataggttcaa
     2461 tgtccgaaat caagtgggtt gagataataa cagaagcatt ttcacaataa ctattaatga
     2521 tggtttttag gatgtagtct cttgcggcag ggtcaactcc accaataggt tcatcaagta
     2581 catagagtct ggctttacga ctcatcacaa gaattaattg tactttttct ttgtttcctt
     2641 tggatagagt tttgaagcgg tcttcagggt ctagttctaa atctcttaga aggcttgttg
     2701 ctttggattt gtcaaagtcg ctgtaaaaat cactaaagaa ctccaacatg tccttaattc
     2761 tcatattttc attgagataa gtagtatctg gtaaataaga aataattttt tttgtctcaa
     2821 cacagggacg gtagccatca atgacaattt ctcctttatt tggttgtaaa aggccattaa
     2881 tgagtttaat taaagttgtt ttaccacttc catttggacc taataatccg ataattttac
     2941 cgttcgggat agtaatggtt aagtcatcaa tagctttttt ttcacggtaa gattttgaaa
     3001 catgatgtag ttgcaatagg tgtgccatta ttgtgaatcc tcctttaaaa agctcgtcaa
     3061 aacagggata atctcagtgt gactaaatcc catttttgtc atattggtga taaatgattc
     3121 taattcacta attgctaact ctcgtctttt acgagcaatt aatttttgat cgtcagttac
     3181 aaaacggcca gcagtacgtt gcgaataaac cattccttcc cgttcaagtt ctgtaaacgc
     3241 tcgttgcatg gtgttaggat taacacctgc gatttctgca tattcacgaa cagttggaag
     3301 ttgatcacca ctcttgattt cttggctaat aatttgcatc atgacatgtt gtgctatctg
     3361 cgcataaata ggagattttt catcaaattt ccaagacatg tggtctcctt tctgagtaat
     3421 atagatattt gtactaatta aatggtacag aaaaaaaaag ggaatgtcaa gttttatgcc
     3481 atttttcact ctttgagaag tagacgtaga ttagagagaa aattgaagca agaaaacctt
     3541 tttcatagta taatagggaa caagataacc aaaggaggaa cttatgtttg ctcaacttga
     3601 tactaaaact gtatactcat ttatggatag tttaattgac ttaaatcatt attttgaacg
     3661 agcaaagcaa tttggttacc acaccatagg aatcatggat aaggataatc tttatggtgc
     3721 ttaccatttt attaaaggtt gtcaaaaaaa tggactgcag ccagttttag gtttggaagt
     3781 agagattctc tatcaagagc ggcaggtgct ccttaactta atcgcccaga atacacaagg
     3841 ctatcatcag cttttaaaaa tttccacggc aaaaatgtct ggcaagcttc atatggatta
     3901 cctctgccaa catttggaag ggatagcggt tattattcct agtaagggtt ggagcgatac
     3961 attagtggtc ccttttgact actatatcgg tgttgatcag tatactgatt tatctcatat
     4021 ggattctaag aggcagctta tacccctaag gacagttcgt tattttgcgc aagatgatat
     4081 ggaaaccttg cacatgttgc atgccattcg agataacctc agtctggcag agacccctgt
     4141 ggtagaaagt gatcaagagt tagcagattg tcaacaacta accaccttct atcaaacaca
     4201 ctgccctcaa gctctacaga atttagaaga cttagtgtca ggaatctatt atgatttcga
     4261 tacaaattta aaattgccac attttaatag agataagtct gccaagcaag aattgcaaga
     4321 cttgactgag gctggtttga aggaaaaagg attgtggaaa gagccttatc aatcgcgctt
     4381 actgcgtgaa ttggtcatta tttctgacat gggctttgat gattattttt tgattgtgtg
     4441 ggatttactt cgctttggac gcagtaaagg ctattatatg ggtatgggac gtggctcggc
     4501 ggcaggtagt ctagtggctt atgctctgaa cattacaggg attgatccag ttcaacatga
     4561 tttgctattt gagcgctttt taaacaaaga acgttatagc atgcctgata ttgatatcga
     4621 tcttccagat atttaccgtt cagaatttct acggtatgtc cgaaatcgtt atggtagcga
     4681 ccattcggcg caaattgtga ccttttcaac ctttggccct aaacaggcta ttcgtgatgt
     4741 tttcaaacgg ttcggggttc cagaatacga actgactaat ctcactaaaa aaattggttt
     4801 taaagatagc ttggctactg tctatgaaaa gtcaatctct tttaggcagg ttattaatag
     4861 tagaactgaa tttcaaaagg cctttgctat tgccaagcgt atcgaaggaa atccaagaca
     4921 aacgtccatt cacgcagctg gtattgtgat gagtgatgat accttgacca atcatattcc
     4981 tctaaaatcg ggcgatgaca tgatgatcac ccagtatgat gctcatgcgg tcgaagctaa
     5041 tggcctgtta aaaatggatt ttttggggtt aagaaatttg acctttgttc aaaaaatgca
     5101 agagaaggtt gctaaagact acgggtgtca gatcgatatt gcagccattg atttagaaga
     5161 cccgcaaacg ttggcacttt ttgctaaagg ggataccaag ggaattttcc aatttgaaca
     5221 aaatggtgct attaatcttt taaaacggat taagccacaa cgttttgaag aaattgttgc
     5281 cactaccagt ctaaatagac caggggcaag tgactatacc actaatttca ttaaacgaag
     5341 agaaggacaa gaaaaaattg atttgattga tcctgtgatt gctcccattt tagagccaac
     5401 ttacggtatt atgctttatc aagaacaagt tatgcagatt gcacagattt atgctggttt
     5461 tacgttaggc aaggccgact tgttaaggcg tgccatgtct aaaaaaaatc tacaagaaat
     5521 gcaaaaaatg gaagaagact ttattgcttc tgctaagcac ctagggagag ctgaagaaac
     5581 agctagagga ctttttaaac ggatggaaaa atttgcaggt tatggtttta accgcagcca
     5641 tgcctttgcc tattcagctt tagcttttca attggcttat ttcaaagccc attacccggc
     5701 tgttttttac gatatcatga tgaattattc tagcagtaac tatatcacag atgctctaga
     5761 atcagatttt caagtagcgc aagttaccat taatagtatt ccttacactg ataaaattga
     5821 agctagcaag atttacatgg ggctgaaaaa tattaagggg ttgccaaggg attttgctta
     5881 ttggattgtt gagcaaagac catttaatag cgtagaggat tttctcacta gaactccaga
     5941 aaaatatcaa aaaaaggttt tccttgagcc tctgataaaa ataggtctgt ttgattgctt
     6001 tgagcctaac cgtaaaaaaa ttatggacaa tttggatggt ttactggtat ttgttaatga
     6061 gcttggttct cttttttcag attcgtcctt tagttgggta gatacgaaag attactcagc
     6121 aactgaaaaa tattctttgg aacaggagat cgttggggtt ggcatgagca agcatccttt
     6181 aattgatatt gctgagaaaa gtacccaaac ttttactccc atttcacagt tagtcaaaga
     6241 aagcgaagca gtcgtactga ttcaaataga tagcattagg atcattagaa ccaaaacaag
     6301 tgggcagcaa atggcttttt taagtgtgaa tgacactaag aaaaagctcg atgtcacact
     6361 ttttccacaa gagtatgcta tttataaaga ccaattaaaa gaaggagaat tctattactt
     6421 aaaaggtaga ataaaagaaa gagaccatcg actgcagatg gtgtgtcagc aagtgcaaat
     6481 ggctattagt caaaaatatt ggttattagt tgaaaaccat cagtttgatt cccaaatttc
     6541 tgagatttta ggtgcctttc caggaacgac tccagttgtt attcactatc aaaaaaataa
     6601 ggaaacaatt gcattaacta agattcaggt tcatgtaaca gagaatttaa aggaaaaact
     6661 tcgtcctttt gttctgaaaa cggtttttcg ataaaaatgg acaattagtg aagtattttg
     6721 caaatgaatg tgctataata ggaccgttaa attaattaaa ggagtaccag aaaatgaaac
     6781 gtattgctgt tttaaccagt ggcggcgacg ctcctggtat gaacgctgct attcgtgcag
     6841 tcgttcgtaa agcaatttca gaaggaatgg aagtttatgg tatcaaccgt ggctatgcag
     6901 gtatggttga tggcgacatt ttcccactgg gttcaaaaga agttggtgat aaaatctcac
     6961 gtggtggaac tttcttatac tcagctcgtt atccagagtt tgctcaactt gaaggtcaat
     7021 tggctggtat tgagcaactt aaaaaacatg gtattgaagg tgttgttgtt attggtgggg
     7081 atggttctta tcatggcgct atgcgcttga cagagcacgg cttcccagcg gtaggtatcc
     7141 caggaacaat cgataacgat attgcgggaa ctgactacac tatcggattt gatacagcag
     7201 ttaacacagc tgttgaagct attgataaac ttcgtgacac ctcatcaagt cacggacgta
     7261 cttttgtggt tgaagtgatg ggtcgcaatg cgggtgatat tgctctttgg gcaggtattg
     7321 ctagtggtgc tgatcaaatc attgttccag aagaagagtt tgatattgaa aaagtggcat
     7381 caacaatcca atatgatttt gaacacaaag gtaaaaatca ccacattatc gtcttagctg
     7441 aaggtgttat gagcggtgaa gcttttgctc aaaaactgaa agaagctggc gataagagtg
     7501 accttcgtgt gacaaatctt ggccacattc ttcgtggggg ttcaccaact gctcgtgacc
     7561 gtgtcattgc ttcttggatg ggttcacatg ctgttgagct acttaaagaa ggcaaaggtg
     7621 gtttggctgt tggtattcac aatgaagaac ttgttgaaag cccaatcctt ggtactgcag
     7681 aagaaggtgc tttgttcagc ttgactgaag aaggcaagat tattgttaat aatccacaca
     7741 aagctcgttt agactttgca gctttgaacc gttcattgtc acaataagtt tagttaaaat
     7801 tgttaaatcg tcaattattg acaaaaaaat aagggagttt cagagtaaaa tgaataaacg
     7861 cgtaaaaatc gttgcaacac ttggtcctgc ggttgaaatc cgtggtggta aaaaatacgg
     7921 agaagatggc tactgggctg gtcaacttga tgttgaagaa tctgcaaaaa aaatcgctga
     7981 attaattgaa gctggtgcga atgttttccg tttcaatttc tcacatggtg accacaaaga
     8041 acaaggtgac cgtatggcaa ctgtccgcct tgcagaagaa attgctcgtc aaaaagttgg
     8101 tttccttttg gatactaaag gtcctgaaat gcgtacggaa ttgtttgcag atgatgctaa
     8161 agagttcagc tatgttactg gagaaaaaat ccgtgtagcg actacacaag gtattcaatc
     8221 aactcgtgat gttattgctt tgaacgttgc tggtagcctt gacatctacg atgaagtaga
     8281 agtaggtcat actattctta tcgatgatgg taaacttggt ttgaaagtga tcgacaaaga
     8341 tatcgcaaca cgtcaattta tcgttgaagt agaaaacgac ggtattattg ctaaacaaaa
     8401 aggtgttaat atccctaaca ctaaaattcc tttcccagca cttgcggaac gcgacaatgc
     8461 tgatatccgt tttggtcttg aacaaggact taactttatt gcaatctcat ttgttcgtac
     8521 agccaaagac gttgaggaag ttcgtgaaat ctgttgcgaa actggtaacg accatgtgca
     8581 attatttgct aagattgaaa accaacaagg tatcgataat cttgatgaaa tcatcgaagc
     8641 tgctgatggt atcatgattg cacgtggcga catgggtatc gaagtaccat ttgaaatggt
     8701 tccagttttc caaaaaatga ttatcactaa agtgaatgca gctggtaaag cagttatcac
     8761 agcaacaaac atgcttgaaa caatgactga aaaaccacgt gcgacacgtt ctgaagtatc
     8821 tgacgtcttc aatgctgtta tcgatggtac tgatgcaaca atgctttcag gagagtcagc
     8881 taacggtaaa tacccggttg aatctgttcg tacaatggcg actattgatc gtaatgcaca
     8941 aactcttctt aacgaatatg gtcgtttaga ttcatctgcc tttccacgta ccaataaaac
     9001 agatgttatt gcttcagctg ttaaagatgc cactcattca atggacatca aacttgttgt
     9061 gactattact gagacaggta atacagctcg tgcgatttct aaattccgtc cagatgcgga
     9121 catcttagct gtaacatttg atgaaaaagt acaacgtgct ttgatgatta actggggtgt
     9181 tattcctgtt cttgctgaaa aacctgcatc tactgatgac atgtttgaag tagcagagcg
     9241 tgttgctgtg gaggcaggct tagttcaatc tggggataat attgttattg ttgctggtgt
     9301 tccagttggt actggtggaa cgaatactat gcgtgttcgt acagtaaaat aaatgtgtta
     9361 taactattta cctaaaggtt agaaggcaag cttctaacct tttttgatat caaaaatatc
     9421 atgttaattc actagtgtta atttacttta atgagtctaa gtttgtattt tatacagaat
     9481 gagaaacgtt tattggtatt gatcaaaaat tgtttacttt ttttctagct tagaacatgg
     9541 tataataaga caatagacta ggagttaata tggtaaagcg agattttata agaaatatat
     9601 tattgttatt aattgtgatt attggggcta ttttgttgag aatctttgtt ttttcaactt
     9661 ttaaagtttc tccagaaaca gctaatactt atttaaagag tggtgattta gtcacaatca
     9721 aaaaaaatat tcagcccaaa tataaagatt ttgtggttta tagagttgga aaaaaagatt
     9781 atgtcagtcg agtcattgct gttgaaggcg atagcgtgac ttatatggac gatatttttt
     9841 acctcaataa tatggtagag tcacaggctt accttgaaaa gatgaaagca cattacttga
     9901 atcatgcacc gtttggcaca ttgtatacag atgattttac agttgctacc atcacagctg
     9961 ataagtatca aaaagttcct aaggggaagt atcttctttt gaatgataac cggaaaaata
    10021 cgaatgacag tcgtcgattt gggttaataa atgcctcgca gattaaaggt ttagtgacct
    10081 ttagagtttt gcctctcagc gattttggat ttgtagaagt agagtagttg tcaggctact
    10141 ctactttttt tataattaga ctataccaat tttatgtttg acaagacatt gtggatatta
    10201 tatactgtaa acatactgtt tttatcggta taatatgact ataccaatta ttgaaattat
    10261 gagagaaagt agcaagttaa cgaacttgtt aaggtaatta agatgtgtgg aattgttgga
    10321 gttgttggaa atcgcaatgc aacggatatt ttaatgcaag gccttgaaaa gcttgaatac
    10381 cggggttatg attcagcagg aatttttgtg gctaatgcca atcaaacaaa cttgattaaa
    10441 tcagtggggc ggattgctga tttgcgtgcc aagattggca ttgatgttgc tggttcaaca
    10501 gggattggtc acacccgttg ggcaacgcat ggccaatcaa cagaggataa tgcccatcct
    10561 cacacgtcac aaactggacg ttttgtactt gttcataatg gtgtgattga aaattacctt
    10621 cacattaaaa cagagttcct agctggacat gattttaagg ggcagacaga tactgagatt
    10681 gcagtacact tgattggaaa atttgtggaa gaagacaagt tgtcagtact ggaagctttt
    10741 aaaaaagctt taagcattat tgaaggttcc tacgcctttg cgttaatgga tagccaagca
    10801 actgatacta tttatgtggc taaaaacaag tctccattgt tgattggact tggtgaaggt
    10861 tacaacatgg tttgttcaga tgccatggcc atgattcgtg aaaccagtga atttatggaa
    10921 attcatgata aggagctagt tattttaacc aaagataagg taactgttac agactacgat
    10981 ggtaaagagc tgatacgaga ttcctacact gctgaattag acttatctga tattggcaaa
    11041 gggacttatc ctttctatat gctgaaagaa attgatgagc aaccaaccgt aatgcgtcaa
    11101 ttaatttcaa cttatgcaga tgaaactggt aacgtacagg ttgatccagc tatcattacc
    11161 tctatccaag aggctgaccg tctttatatt ttagcggcag ggacttccta ccatgctggt
    11221 tttgcaacaa aaaatatgct tgagcaattg acagatacac cagttgagtt gggagtggct
    11281 tctgagtggg gttaccacat gcctctgctt agcaagaaac caatgtttat tctactaagc
    11341 caatcaggag aaaccgcaga tagtcgtcaa gttttagtaa aggcaaatgc tatgggtatt
    11401 ccgagtttga cagtaactaa cgttccagga tcaaccttat cacgtgaagc aacatacacc
    11461 atgttgattc atgctggacc tgaaattgct gttgcgtcta caaaagctta cactgcacaa
    11521 attgctgccc ttgccttttt ggctaaggca gttggtgagg caaatggtaa gcaagaagct
    11581 cttgacttta acttggtaca tgagttgtca ttggttgccc aatctattga ggcgactttg
    11641 tctgaaaaag atctcgtggc agaaaaggtt caagctttgc tagctactac tcgtaatgct
    11701 ttttacattg ggcgtggcaa tgattattac gttgcgatgg aagctgcttt gaaattaaaa
    11761 gagatttctt atattcaatg cgaaggcttt gcggctggtg aattgaaaca tggaaccatt
    11821 tcattgattg aggaggacac gccagtaatc gctttaatat cgtctagtca gttggttgcc
    11881 tctcatacgc gtggtaatat tcaagaagtt gctgcccgtg gggctcatgt tttaacagtt
    11941 gtggaagaag ggcttgaccg tgagggagat gacattattg tcaataaggt tcatcctttc
    12001 ctagccccga ttgctatggt cattccaact caactgattg cttactacgc ttcattacaa
    12061 cgtggacttg atgttgataa gccacgtaat ttggctaaag ctgtaacagt agaataaatg
    12121 attataatgg ataaggcaac catctgttag gtggttgctt tttgttttta ggagaatagc
    12181 agagcttaga aaatggcctt gagaaaagct atacaagaag aatagtcatc ttctgatgag
    12241 aacgtattca tcttgtcaaa tcattgattc taaagtaaaa tggtaacatt aagaaatgtt
    12301 taggagtgta agatgtcatt accaaattgt ttgcaatgcc agtctgaata tgtttacgaa
    12361 gatggtcttt tattaatctg tccaatgtgt gcttttgaat ggacaccagg cgaagaagcg
    12421 actgaagaag aaggacttgt tgttttagat agcaatggtg tccgactgtc tgatggtgat
    12481 accattactg tggttaaaga tttgaaagta aaaggcgctc caaaagacct gaaacaaggg
    12541 actcgtgtta aaaatattcg cctggtggaa ggtgatcata acattgattg taagattgat
    12601 gggtttggcg cgatgaaatt gaaatcagaa tttgtcaaga aaatctaata ataatacgca
    12661 accagctgat ctggttgtat ttttataaaa aaacctctcc ccaaatacgt tcaaatttgg
    12721 tataatagta aaatattcag ttttaggagg caacatgacc tatattcagc aagttttacc
    12781 cagcttatta gatggtgcct tggtgacctt acaagtattc tttattgtta tcattctttc
    12841 tataccctta ggggctattt tagctttctt gatgaagatt ccctttaaac cgctacagtg
    12901 gtttttgacc ctatacgtgt ggatgatgcg agggacacca ttactacttc aattgatttt
    12961 tttctattat gttttgccaa gtgtggggat tagttttgat cgaatgccag ctgctatttt
    13021 ggcgtttact ttgaattatg ctgcctactt tgctgaaatt tttagaggtg ggattgaggc
    13081 tattccaaaa ggtcaatatg aagcagctaa agtattaaag ttaaaacctc ttcaaaccat
    13141 tcgttatatt attttgcctc aagtgtttaa aattgtgtta ccaagtgttt tcaatgaagt
    13201 cattaatttg gtcaaagatt cttcccttgt ctatgtactc ggtgtaggag atcttttatt
    13261 agcaagtaag acggcagcca atagggatgc aaccttagcc cctatgttta tcgctggtct
    13321 tatctatttg cttttaattg gactggtcac gattatttca aaacaagttg aaaaacggtt
    13381 taattattat cagtaaggag gcttcatgtt agaactcaaa aatatttcca aacagtttgg
    13441 tcaaaaaacc atttttgatg gctttaatct aaccgttcaa gacggagaag tgctctcttt
    13501 ggtaggccca tcaggtggcg gtaagacaac actcttacgg atgttggctg gtcttgaatc
    13561 tattgattca ggtcaagtct tttacaatgg cgaagatgtt ggtattgatc atttggaaaa
    13621 tcgtaacttg cttggatttg tttttcaaga ttttcaattg tttcctcatc ttaccgtttt
    13681 agacaaccta acgctgtctc caacaattac aatgggcaag caaaaatctg acgctaaaga
    13741 aaaggctttg gatttactgg cacgtttagg attaaaagaa catgcccaag tttatcccta
    13801 ttcgttatct ggaggtcaaa aacaacgggt tgctttggca agagccatga tgattgaccc
    13861 tcaaattatc ggttacgatg aaccgaccag tgctctagat cctgaattac gtcagacggt
    13921 agaagccttg attgttcaaa accgtgaaat gggaataact caaattgtag tcactcacga
    13981 tcttgttttt gccgaagcca tctcagatcg tattattagg gttaatccta aatagaagag
    14041 gacccaaaag atgattataa aaaaaagaac cgtagcaatt ttagccatag ctagtagctt
    14101 tttcttggta gcttgtcaag ctactaaagg tcttaaatca ggagatgctt ggggagttta
    14161 ccaaaagcaa aaaagtatta cagttggttt tgacaatacg tttgttccta tgggctataa
    14221 ggatgaaagc ggcaaatgca aaggttttga tattgatttg gctaaagaag tttttcacca
    14281 atatggactc aaggttaact ttcaagctat taattgggac atgaaagaag cagaactaaa
    14341 caatggtaaa attgatgtaa tctggaatgg ttattcaata actaaggagc gtcaggaaaa
    14401 ggttgccttt actgattctt acatgagaaa tgaacaaatt attgttgtca aaaaaagatc
    14461 tgatattaaa acaatatcag atatgaaaca taaagtgtta ggagcacaat cagcttcatc
    14521 aggttatgac tccttgttaa gaactcctaa actgctgaaa gattttatta aaaataaaga
    14581 cgctaatcaa tatgaaacct ttacacaagc ttttattgat ttaaaatcag atcgtatcga
    14641 tggaatattg attgacaaag tatatgccaa ttactattta gcaaaagaag ggcaattgga
    14701 gaattatcgg atgatcccaa cgacctttga aaatgaagca ttttcggttg gacttagaaa
    14761 agaagacaaa acgttgcaag caaaaattaa tcgtgctttc agggtgcttt atcaaaatgg
    14821 caaatttcaa gctatttctg agaaatggtt tggagatgat gttgccactg ccaatattaa
    14881 atcttaaaaa ggacacttgt cctttttttg tttaacaggt gagatctagc agacaaagtc
    14941 agctagatga tttaataaaa atcttagttt aaggtttttt tattaa
//
LOCUS       DATWEK010000036        14815 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.036, whole genome shotgun sequence.
ACCESSION   DATWEK010000036 DATWEK010000000
VERSION     DATWEK010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14815
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.036"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(130..891)
                     /locus_tag="VCR92_001460"
     CDS             complement(130..891)
                     /locus_tag="VCR92_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEP4268520.1"
                     /translation="MTKEKMMSFMTIASIALLGSGVVCANDVADPVAGTTDAVVVPVS
                     PQPTTPIEHTGTDTTNKIVDSTKPSEDKVADSTDQLIPPVKSDLETSEDKVTDPTETK
                     PSKEKTEEPVKSNDSEVIPEQPKSEEVKKAEENTGASTTETPKPVTKPVIETPIVTNT
                     GYTVLGTQDGNVWVQTETGNVLKPAIAIGAVKQKDGTVALKTRDGKLEVLPSTGETKT
                     ILAILGGLAILGAIWVGWKENIKKYLTFLKKKSKK"
     gene            complement(916..1473)
                     /locus_tag="VCR92_001461"
     CDS             complement(916..1473)
                     /locus_tag="VCR92_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268521.1"
                     /translation="MKIRKVIIVMLAVALSLGFYRLYHRQKPSQLIEANQEILVKPIT
                     PNKSKIKVKRNVAKEAKATLEMPEERVNEKEAKQVKSAIVIPIDYLASISSQDDIKVT
                     YDNKLSITNPAMAASIKTMLLAGYHFDLDSLTVYQSNSDNVYQFTILLVTHQQDQLSL
                     VGNYVTGTGQFEFVSLHGTPKNVMF"
     gene            complement(1473..2825)
                     /locus_tag="VCR92_001462"
     CDS             complement(1473..2825)
                     /locus_tag="VCR92_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEP4268522.1"
                     /translation="MSIPFFIVVIVTIIFSSSQGDCQVTPDLSTQFVTSSDSASQTDW
                     TKKGSIANVTAGKVFHAWVSKGLSGASAAGIVGWVNSEGGFAMIGRAEGHYGNDLRTN
                     SIAFGVKPIGLSYYTTEAGGGIYQFTPYTKYAPLGDPKWENADAMNEFVAKAILAGDW
                     NASMDLTGGNHTFKQMAQMTDPKQATLVWQAYERGSTAHINPFQKQADAQKAYELFGG
                     VKYSYNEIVFHKSFDIFGPLKPGEGESKEVVLSLCESGSYSKGAFGKDRTGKVNYTSY
                     NAWRPEQLPADLKPYALDPRSVGLNYRQAVGWYAIASTGGQCTDLSASLMYALWSKNG
                     SHPTQKAGNGNMVVANWVRTFGGSSDKSPTSGAVFSSAGTSSAGHTGVVSHVFENGDI
                     LIVEQNYASYSGDDGGFGKYSWNYRYVTTAELKNEGYTFYNPAKLGYQIMKSVGTVGK
                     "
     gene            2966..3109
                     /locus_tag="VCR92_001463"
     CDS             2966..3109
                     /locus_tag="VCR92_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEP4268523.1"
                     /translation="MGNSSKSNRKEELDLSTFEVLTLMFIAGNFVIALVKLVLELVKS
                     TKK"
     gene            complement(3277..3846)
                     /locus_tag="VCR92_001464"
     CDS             complement(3277..3846)
                     /locus_tag="VCR92_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268524.1"
                     /translation="MGKHSPMNFSKPSQMTESIDHDVHYDLPGVNEEMESPFQSESDY
                     QSQNSSIIVETPEMDDMIYQSSQKKNISIGNNYSSDKKSLENSFDSPIIPERSEPETD
                     AKERFNPQAEYQRLKAKRQKPLGNRKKSKLEAELGQFTDDASYYKAHGGTAFKRGFNA
                     SKSKELRLKQNLERKATILAELDKLRGHV"
     gene            complement(4420..5592)
                     /locus_tag="VCR92_001465"
                     /pseudo
     CDS             complement(4420..5592)
                     /locus_tag="VCR92_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5607..8108)
                     /locus_tag="VCR92_001466"
     CDS             complement(5607..8108)
                     /locus_tag="VCR92_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEP4268525.1"
                     /translation="MVKKLEYPINSIHSNLALRKDKVVIAYYRIPNTPITITDSDKKD
                     SHKDKVAQVIKKLAKYKHFDISLVPKDYLLEEKMSDFIGDLADDVKDLGIDTLSYTVD
                     TLTAEIEIPYQFDWVIGVNLGRDTMSATLKELAVKQLDLIADNVASLLGYTVELDKEW
                     YKEYQDEELLLYGLLSSLKAKRLSEEDLFYYQRMQYLRYIPHAKNEVIANRTLLNVTD
                     TLVKPLSGGFLKLESPYGSSFITILPVGKFNTIFNGFHLGELVQRMSFPVELRFKAEF
                     INKTKLSGTMGRSNTRYDQIMKEAYSTNTVQQDDILMGSYSLKDLMKKVGNKEEIIEY
                     GCFLVVSGSSIKQLRQRRHAVLSYFADMQVNVHEASHDTPYLFQTLLYGQNLQKTTRK
                     WNHLVTSRGFSEMMLFTNTQSGNRIGWYIGRVDNRLSAWDNIGEAIMGSKNLVLFNAT
                     VANKEDVAGKVTKNPHIIITGATGQGKSYLAQMIFLHTAQQNVRVLYIDPKRELRKHY
                     LQVVSDPEYAKQFPLRKHQIEQINFVTLDSAMKENHGVLDPIVILDKEDASSTAKNIL
                     LYLLRNATEVKIVQTTALTEAISEVISRRENGEVVGFNQVIETLCQSDNQDIVDVGHY
                     FKAIIKNSILELAFSDGNVKGLSYEERVTVLEVADLSLPKDGSDHISDHESNSIALMF
                     ALGAFCKHFGERTNEETVEIFDEAWILMQSSEGKAVIKSMRRVGRSKYNVLMLVSQSV
                     HDAENDDDTTGFGTIFAFYEKSEREAILTHVGLEVNEKNLEWIDNMISGQCLYYDVYG
                     NLNMMSVHNIHPDIDPLLKPMKQSVSSHLENKYAS"
     gene            complement(8129..8539)
                     /locus_tag="VCR92_001467"
     CDS             complement(8129..8539)
                     /locus_tag="VCR92_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEP4268526.1"
                     /translation="MEEEKYFDYSRGLNAPYWIQEIKTSKGKLLWYFSTPMQLSFFIV
                     FFLILVLMLTVFSAPMQLLNQLTHSISLLLYWFVPYRLSKFYTEYEPQGKKMHTYLWD
                     YLVYLIDYGFNKKAIYQGERVEVLEEIVFEKTNI"
     gene            complement(8542..8811)
                     /locus_tag="VCR92_001468"
     CDS             complement(8542..8811)
                     /locus_tag="VCR92_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268527.1"
                     /translation="MKVSKVAQVVLTGGGPNVSGLKQFFQGDGIYLISVICAFLVIKN
                     WKNADWLKVGSVLSIYAIVVSLFKGQEILAFLGGMLRWFGIETGL"
     gene            complement(8830..9780)
                     /locus_tag="VCR92_001469"
     CDS             complement(8830..9780)
                     /locus_tag="VCR92_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEP4268528.1"
                     /translation="MDYLVKIKKFLLRYTKKEKGGKQPKPKEVKQKTANIIVYGILGL
                     LFIVGFFGSLRAIGLSNQVNSLKATVLSSKQQNGKDTKEILDIPRVQYYMNNFVYTYI
                     NYSDDTATKRKEELDNYYSFSTANLVDDVKKERKLQTQRLVSVEQEEDYHIALMRIGY
                     EVDSKSYQMTLAIPFRMANGLLAIVSPPYTLAEDLFQGKSKSFERKTVDQVKSLPKQE
                     MLSIQKFLPVFFDKYALSNEIDLKLLMKHPELMGGNYRVKSLDANNARYYQDKSNQVV
                     QLMVTFEDMVTGGTRSENFTLYLIKSDNGWYVDKLYHYFK"
     gene            complement(9781..10260)
                     /locus_tag="VCR92_001470"
     CDS             complement(9781..10260)
                     /locus_tag="VCR92_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268529.1"
                     /translation="MIAIIRTHEKGRSQFLCELDIMQFTENQVRDHMIERGIKDDAFF
                     ICGFSDWNVDRIMSLSEVYLLKRCIVGLYDGDDYIVQYLLKKGLSVPAIVTKFYVFLS
                     KDEKEAMGYVLKNVSFDSLIDFWQRSVTWANALNAYIQSGILLNTSKGFYVLKTEGG"
     gene            complement(10268..10749)
                     /locus_tag="VCR92_001471"
                     /pseudo
     CDS             complement(10268..10749)
                     /locus_tag="VCR92_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000383283.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
     gene            complement(10802..11074)
                     /locus_tag="VCR92_001472"
     CDS             complement(10802..11074)
                     /locus_tag="VCR92_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268530.1"
                     /translation="MSNTRSEADKKLLVVTQELSELLISHQYDQSWEKAGELNSLLKK
                     REELTLPGYMVDMIQQHLKSYYYQNNMINKAHKSMSAIGHKLQEFH"
     gene            complement(11207..11412)
                     /locus_tag="VCR92_001473"
                     /pseudo
     CDS             complement(11207..11412)
                     /locus_tag="VCR92_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057932.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(11463..11840)
                     /locus_tag="VCR92_001474"
     CDS             complement(11463..11840)
                     /locus_tag="VCR92_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000287184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268531.1"
                     /translation="MFLENEFNYFISTRNNLELVIDSLVLMIPDREFYYPEIQTGELR
                     DYQIDIYDLIKIGYVGVYEIQKDYEDKLRELADFKRKLLKFGLLMQPLEKQKEIVIRL
                     AAKYHLEKRILMKKEMFRDEEVD"
     gene            complement(11841..13082)
                     /locus_tag="VCR92_001475"
     CDS             complement(11841..13082)
                     /locus_tag="VCR92_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEP4268532.1"
                     /translation="MNPMYLKKFRKKSGLKQKEFAKCIGISQAMLSQYESGKKKLSLE
                     KFQEMKTHFGYLTDNDSSRLQVTIDYVRITLKSVRDLEFFCRNFLHCRFKEFSSVESK
                     LMNYNHIWKRGDIWIFDYADKHDTGNYQITLQLSGQGCRQLELLMEQENFAWLDWLIY
                     LRRSYRDEMNVTRFDLAIDELYLGKDRENEHFLLSDMIAKYYHHELAFESLRTWNYIG
                     GGALNFNDMEEIEQNRQGISLYFGSRQSEMYFNFYEKRYELAKLEGISVEESLEIFEI
                     WNRYEIRLSQSKANAVVDEFISGIPLGEIARGLINSKIQVYDGKNKYGAFMADQKWQM
                     MFGGVEPLTFVTRPESYNIERTIRWLIHQVSDSLAMVSEYDSMIDGDNLQMIINSGEV
                     NERGEKILETIRYNLGLDKGA"
     gene            complement(13394..>14815)
                     /locus_tag="VCR92_001476"
     CDS             complement(13394..>14815)
                     /locus_tag="VCR92_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HEP4268533.1"
                     /translation="ENGFVYEKRKKVNKKQKVSFPKVYLKQGKFDLSVSFEMAGNKFQ
                     KRFKDIGGELEDTFFMDFMEKTDDPRFKIYKLAYSAFLARITVNDVVWEKDKGIKLMN
                     GYYWDFINDPHLLVAGGTGGGKTVLLRSILKCLATIGVADICDPKRADFVTMADLPAF
                     RGRIVFEKVDIIAKFENAITIMYARYDFIRKEMKRLGHKDMGKFYDYGLEPYFFICDE
                     YNALMSSLSYQERDIVENAFTQYILLGRQVGCNAIIAMQKPSADDLPTKIRSNMMHHI
                     SVGRLDDGGYMMLFGDENRNKEFRYIKFLSGHRVYGRGYSAVFGEVAREFYAPLLTKK
                     FSFYDEFAKISRHDNPFDPLENTLVSKDIISDESLRKFVEKTSDNELPKGSIGFDFEE
                     EMEEINHMSIGDLAKKTGFSFGKIKNLIDMIEKDGYMTFNREDERVVLTDSDAVILNS
                     LLTQKDKFDGSWKELLLNYFKGE"
BASE COUNT         4741 a         3101 c         2011 g         4962 t
ORIGIN      
        1 gctagatatt gtttcaatta atttcaataa aataatacta taaattaatg ctatgaaata
       61 atatactagt cttttcaatt tcgctccttt caacaaaact aaagccatga aattaatcat
      121 ggctttatct tattttttac ttttcttttt caaaaacgtt aaatactttt tgatattttc
      181 tttccaacct acccagatag ctcctaaaat agctaaacct cccaaaatgg ctaagattgt
      241 tttagtctct ccagttgatg gtaagacttc taacttccca tctcttgttt ttaaggcaac
      301 tgtaccatct ttttgcttta cagcaccaat tgctatcgca ggtttcagta cattaccagt
      361 ttctgtttga acccaaacat tgccatcttg cgttcccaaa accgtgtagc ctgtattcgt
      421 aacaattggt gtctcaataa caggtttcgt cacaggttta ggagtttcag ttgtactagc
      481 acctgtattt tcttcagctt ttttcacctc ttctgactta ggttgttctg gaatcacttc
      541 tgaatcattg gacttaacag gctcttccgt cttctctttg cttggcttag tctccgttgg
      601 atctgttact ttatcctcgc ttgtttctaa atctgattta actggaggga ttagctgatc
      661 agtactatct gccaccttgt cctcgcttgg cttagtcgag tcaacaattt tattggtagt
      721 atctgttcct gtatgctcaa tcggtgtcgt tggttgaggt gagactggta ccaccactgc
      781 atccgttgtt cctgctactg gatctgctac atcattagca caaaccaccc cacttccaag
      841 caaagcaata cttgcaatcg tcataaaact catcattttt tcttttgtca tcttattttt
      901 cctcttttcg tttaattaaa acatgacatt ttttggagtg ccatgtaaac tcacaaattc
      961 aaactgaccc gtaccagtaa cataattacc aacaagactt aattgatctt gctgatgagt
     1021 cactaataaa atcgtaaatt gatacacatt atcagaattg ctctgataaa ccgtcaagct
     1081 atctaaatca aagtgatacc ctgctaaaag catcgtttta atgcttgctg ccattgctgg
     1141 attagtaatg gacaacttat tatcataagt aaccttaata tcatcttgac ttgatatact
     1201 agctaaataa tcaatcggta ttacaatagc tgatttcacc tgtttagctt ctttttcgtt
     1261 aacacgctcc tcaggcatct ctaaagtggc cttggcttct ttggcaacat ttctcttaac
     1321 cttaatttta cttttattcg gtgtaattgg ttttacaagt atttcttgat tagcttctat
     1381 taactgagat ggcttttgac gatgatacaa ccgataaaat cctaatgaaa gagctactgc
     1441 cagcataaca ataataactt ttcttatctt cattatttac ctaccgttcc tactgatttc
     1501 ataatctgat aaccgagttt cgcaggattg taaaaagtat atccttcatt ttttaattct
     1561 gcagtagtga catagcgata gttccaagag tatttcccaa agccaccatc atcacccgaa
     1621 taagatgcat aattttgttc cacaattaaa atatccccat tttcaaaaac atggctgaca
     1681 acacctgtat ggccagcaga actagtccct gcagaggaaa atacagctcc tgaagttggt
     1741 gatttatcag atgaaccgcc aaaagtccta acccaattag caacaaccat attaccatta
     1801 cctgcctttt gtgttggatg gctaccattt tttgaccaca aagcatacat caaactcgca
     1861 gaaagatcgg tacattgacc ccctgtcgaa gcaatcgcat accagccaac cgcttgtcga
     1921 taattcaagc caactgatct gggatcgagc gcataaggtt ttaaatctgc aggcaattgt
     1981 tctggtcgcc aagcattgta ggaagtatag ttgactttgc ctgtacgatc tttcccaaaa
     2041 gcccccttag agtaagaacc tgattcgcat aatgataaaa cgacttcttt tgattcccct
     2101 tcccccggct ttagtggacc aaaaatgtca aaagatttat gaaatactat ttcattataa
     2161 ctatatttaa ctccaccgaa taactcatac gctttttgag catctgcttg cttttgaaat
     2221 ggattaatat gggcagtact accacgttca taagcttgcc aaactagcgt agcctgtttc
     2281 ggatcggtca tctgggccat ttgcttaaag gtatgatttc ctcctgtcaa atccattgaa
     2341 gcattccaat caccagctag aatggctttt gcaacaaatt cgttcatggc atccgcattc
     2401 tcccacttag gatcacctaa aggggcatat ttggtataag gggtaaattg ataaatacct
     2461 ccacctgctt ctgtcgtata gtaactcaaa ccaattggtt tcactccaaa agctatagaa
     2521 ttagttcgta aatcattacc ataatgtcct tctgctcgac ctatcatggc aaaaccacct
     2581 tcggaattaa cccaacctac aattcctgcg gcagaagcgc ctgacaagcc tttcgatacc
     2641 caagcgtgaa agactttacc tgctgtgaca ttcgcaattg agcctttctt tgtccaatcg
     2701 gtttgtgaag cagaatcact tgaggtaaca aattgtgttg ataaatcagg agttacttga
     2761 caatcacctt gactgctgct aaatatgatc gtaacgataa ctacaataaa aaaaggaatg
     2821 ctcataagca ctcctagaca tccaagtttc ttcttgataa cattccctcc ttcttaaact
     2881 ggtcagacag agatacggta tgttataata aaaaggcaga aaagttaaga cggtggctct
     2941 tatttctgaa aggtaggtgg tgcccatggg caattcatca aaatccaaca gaaaggagga
     3001 gctagatttg tctacctttg aggtcttaac actcatgttt atagcaggta acttcgttat
     3061 cgctctcgtg aagttagtcc ttgaactggt aaaatcgaca aaaaaataac cgtctcaact
     3121 ttggcgagtt aacggttatt ttttaacggt tattttctgc caccgtctta aacggttctg
     3181 cattgggtag ttgtttccgc aactgccctt ttctattttc attataactc ttatctccaa
     3241 attaagcaac tatttgataa catcacaata cttcctttaa acatgtcctc taagtttatc
     3301 taattcagct aaaatagtcg cctttctttc taaattttgt tttaaccgta actcttttga
     3361 tttactggcg ttaaatcctc ttttaaaggc agtccctcca tgtgctttat aatagctggc
     3421 atcatcagta aactgaccta attctgcttc taatttagat tttttccgat ttcctaaagg
     3481 tttttgtcgc ttagctttta gacgttgata ttctgcttga ggattaaatc tctctttagc
     3541 gtccgtttct ggttcagacc tttcaggaat aattggagaa tcaaatgaat tttccaaaga
     3601 ttttttatca gaggaataat tatttccaat agaaatattt ttcttctgac tgctttgata
     3661 aatcatatca tccatttctg gagtttcaac gataattgaa gagttttgag attgataatc
     3721 actttctgac tgaaatggac tttccatctc ctcattaaca cctggtaaat cataatgaac
     3781 atcatgatca attgattcag tcatctgact tggtttagaa aaattcattg gggaatgttt
     3841 acccaagggt tctgaattat ctaatgaagc tccaaaagat tggctgtata agttgtctct
     3901 ttcaaaatca cttacttgag agagattgta atcagaagaa aagttactct cttgattatc
     3961 gaaaacacct tgttctgctt gatgtccaga ggtaggatta ccattatcag aaacatgcgg
     4021 gacactattt gtggaaaatt cttgatctcc tgcaaaatct cctaattctg aaaactgatg
     4081 gtcgaaatta gtttcattag aaaggtcact ataattagaa gtgtcatctc ctttgaaacg
     4141 gtttttaatg gcactaagat tatccttagc atgtacaagg ctaccaacac cataaccagc
     4201 tcccatcatc gcaagattag aaatatcatg cgccttatca tagatatttt ggggtgtaac
     4261 tcctaaacta ttcgcttttt gagcaaccat atttcctgct tgtgtgactg cttgtgcagc
     4321 gtctgctcct acaattaaac ttaatacctt ttctttatgt ttccaaattt gccaaaaaat
     4381 aaccccctga acaacaatag taataaacaa cataaataaa atagattgtc ccttaaggtt
     4441 actgctgctt aacaaatgat tgtctgtaaa tcgagactta ataaatgtcg caatcaatga
     4501 ctgtatataa aagactatta aagttaaaaa acctgttaga gctggaaagg aaacacctcc
     4561 aagcattagc ttaagcatat taaaagcaat atgttgcatt ttaggtaaaa aggacaccaa
     4621 taaagccagt gggaataaaa acattaacaa tatgaccaca atatctgcta aaaaagcaat
     4681 taattgtatc aataataaag gtatagctaa tatcactgct tcaaaaattt tcaaaataac
     4741 ataaatagac ttgatccaaa tatagtcact aacagctgac atccacctgt tttgttcttc
     4801 tcctttcaaa gctccgtcac caagtttatt tgtatactct aatatttgtt gactttttgg
     4861 tattacaaac tgatttgact tatcatattt tcccagaatt ttgctattat ctaactcctc
     4921 ttcttttcct gatttattat tatgaaactt accatttaac tggccagtat ttacaaaaag
     4981 ataagctgta taagacgttt tcataacata attatcagct accgaagcct catgagaaat
     5041 gatttgcttc tcatcttctg gactcactac cgatagatta gttactgcat cactaaaaga
     5101 actagctacc gaatgaacca tatccaacac atagacaccg cccgaagttg actgcaccgt
     5161 cccaaagtaa ccgaacgcta ataacataac cgcaaacaaa tgaagtaatc gtcttgaaaa
     5221 atcacctttt gaaaaaataa aagctagaaa aatggaaaaa gcggataagg caattaagag
     5281 ataaagtaat gaattcgtaa aatctgcgga tttagagagg ttatcccaca aaactttgga
     5341 actatcaaac acagtctgac gataagtatt atacaagcta aagttttcaa aaaatcgtag
     5401 aataatggaa aagaaaccaa caatcaagtt aagtagaaaa aagggaaaat taacaaaaat
     5461 atctgtcaaa gttacttgta accccgtctc aagaccttct gtactttcca tgtaagcctt
     5521 taatgcaaaa atatccacat ccttgacttt ctgaaaggta gaagctatta atccatcatc
     5581 aatcttatcc atttggcctc tcctttctac gaagcgtatt tattttctaa gtggcttgaa
     5641 acagactgtt tcattggttt taataaggga tcaatatctg gatgaatgtt atggacagac
     5701 atcatattga ggttgccata aacatcataa taaaggcatt gtcctgaaat catgttatca
     5761 atccactcca ggttcttttc gttcacttcc aaaccaacat gagttaaaat agcttcccgt
     5821 tctgattttt cgtaaaaagc gaaaatagta ccaaaaccag tcgtatcgtc atcattttcg
     5881 gcatcatgta ctgattgaga cactaacatt aaaacattgt acttagaacg accaacgcgg
     5941 cgcatagact tgataacggc cttaccttct gatgactgca tcagaatcca agcctcatca
     6001 aaaatttcaa cagtttcctc attggttcgt tccccaaagt gcttacaaaa agcacctaaa
     6061 gcaaacatta aagcgattga attactttca tgatcagata tatgatctga accatcttta
     6121 ggtaacgata agtccgcaac ttctaaaact gtcacacgct cttcatatga taatccttta
     6181 acattaccat ccgaaaaagc caattccaaa atagaattct taataatagc tttaaaataa
     6241 tgtcctacat ctacaatatc ctgattatct gattgacata atgtctcaat gacttgatta
     6301 aagccaacga cttccccatt ttcacgtctt gagattactt cactaatggc ctctgtcaaa
     6361 gcagtagttt gtacaatctt aacttctgtc gcatttctta acagataaag caatatattt
     6421 ttagcagtag acgaggcatc ttctttatcc aagataacga taggatctaa aaccccatgg
     6481 ttttccttca tcgcactatc caatgtcaca aaattaattt gctcaatctg atgttttctc
     6541 agtggaaatt gtttcgcata ctcgggatca gacaccactt gtaaatagtg tttccttaac
     6601 tctctcttag gatcaatata aagcactcta acattttgtt gcgcagtatg taaaaaaatc
     6661 atctgtgcaa ggtaggactt cccctgacct gtcgcacctg taatgataat atgaggattt
     6721 ttagttactt taccagcaac atcctcctta ttcgcaaccg ttgcattaaa caaaactaag
     6781 ttcttcgagc ccataatcgc ttcaccaata ttatcccaag cagataaacg attatcgact
     6841 cgaccaatat accagccaat cctgttacct gactgggtat ttgtaaataa catcatttca
     6901 ctaaacccac gactggtcac taagtgattc catttacgtg ttgtcttctg taaattttga
     6961 ccataaagta acgtttggaa taaataaggt gtatcatgac tagcttcatg tacattgact
     7021 tgcatatccg caaagtaact taaaacagca tgcctacgtt gccttaattg tttgatacta
     7081 gacccagaaa ccaccaaaaa acaaccgtat tcaatgattt cttctttatt tccaactttc
     7141 ttcatcaagt cttttaatga atatgagccc attagaatat catcttgttg cactgtattc
     7201 gtggagtagg cttctttcat aatttgatca taacgtgtat tcgagcgtcc cattgttcca
     7261 cttaacttag ttttattaat aaattctgct ttaaatcgta actcaacagg aaaactcatc
     7321 cgctgtacga gttcacctaa gtggaaccca ttgaagatag tattaaactt cccaactggt
     7381 agaatcgtta taaatgaact accatacgga ctttctaact ttaaaaaacc tcccgacagg
     7441 ggcttaacta aagtatctgt tacgttcaac aatgttctat tggcaataac ttcattttta
     7501 gcatgtggga tatagcgtaa gtattgcatg cgttgataat aaaataaatc ttcttcagat
     7561 aatctcttag ctttcagtga tgataacaaa ccatacagca ataattcttc atcttggtac
     7621 tctttatacc actccttatc aagttccaca gtgtatccca acaaagaggc gacattatct
     7681 gcaattaaat ccaattgctt taccgcaagt tcttttagtg tagcactcat tgtatcccta
     7741 cctaaattaa caccaataac ccaatcaaat tgataaggta tttcaatctc agctgtcaac
     7801 gtgtcaacag tgtaactcaa tgtatctata cctaaatcct taacatcatc tgccaagtca
     7861 ccaataaaat cagacatttt ttcctctaaa aggtaatctt ttggtaccag tgaaatatca
     7921 aaatgcttgt atttagctaa ttttttgata acctgtgcta ccttgtcttt atgactatct
     7981 tttttatcac tatcagtaat agtgattggc gtatttggaa tccgatagta ggcaataacc
     8041 actttatctt ttcgcaaagc taaattactg tgaatgctat taattggata ttccaacttt
     8101 tttaccatct gatctccttt cttaatcttt aaatgtttgt tttctcaaat acaatttctt
     8161 ctagtacctc tactctttct ccctgataaa tagctttttt attaaaacca taatctatta
     8221 aatagacaag ataatcccaa agataagtat gcatcttttt accttgtggc tcatactccg
     8281 tataaaattt tgaaagtcga tatgggacaa accagtacag taacagagaa atagaatgcg
     8341 ttagctgatt tagcagttgc ataggagccg aaaagactgt caacatcaat actaaaatca
     8401 aaaagaaaac aataaaaaag gaaagctgca ttggtgttga gaaataccac aataactttc
     8461 cttttgacgt ttttatttct tgaatccagt aaggggcgtt taggccccta ctgtaatcaa
     8521 aatatttttc ttcttccatt tttataaacc tgtctcaata ccgaaccagc gaagcatccc
     8581 tcctaaaaag gcaagaattt cttgcccttt aaacagagaa accacaatcg cataaattga
     8641 cagtactgag ccaactttta gccaatctgc atttttccaa tttttaatca ctaaaaaagc
     8701 acagataaca ctaataagat aaatcccatc tccctgaaaa aattgtttta gtcctgaaac
     8761 attaggtcct cctcctgtta aaacaacttg agctactttt gatactttca ttaattaaac
     8821 ctcgcttttt tatttaaaat aatggtacaa cttgtcaaca taccaaccat tatctgactt
     8881 aatcagatac agcgtgaaat tctctgaccg tgtacctcct gttaccatat cttcaaaggt
     8941 aaccattaat tgcacaactt gatttgattt atcttgataa taccgagcat tgttagcgtc
     9001 taaagatttg actcgatagt ttccacccat cagttcagga tgcttcatta gtaacttcag
     9061 atctatttca ttacttaaag catacttatc aaaaaataca ggtaaaaatt tttgtattga
     9121 taacatttct tgcttcggta aactcttgac ttgatccaca gtttttcttt caaaactttt
     9181 tgatttccct tggaaaagat cctccgctaa ggtatatgga ggacttacta ttgccaataa
     9241 tccattagcc atacgaaatg ggatagccaa cgtcatctga taagatttac tatctacctc
     9301 atagcctatt ctcattaaag caatatgata atcctcttct tgttctacac taaccagtcg
     9361 ttgagtctga agcttacgct cctttttaac atcatcaaca agattagctg ttgaaaaaga
     9421 ataataatta tctaattctt ctttacgttt tgtagccgta tcatcagaat agttgatgta
     9481 agtatacaca aaattgttca tgtaatactg cactctagga atgtctaaga tttcctttgt
     9541 atcttttccg ttttgttgct tgcttgataa aaccgtagct tttaaactat ttacttgatt
     9601 tgacaaacca attgccctta atgagccaaa aaatcctaca ataaataata atcctaaaat
     9661 tccatagaca ataatattgg ctgtcttttg ttttacttcc tttggtttag gctgctttcc
     9721 tcctttttct ttctttgtat atctcaatag aaactttttt attttcacta aataatccat
     9781 ctaacctcct tctgttttta acacataaaa tcctttggat gtatttaaca atattccact
     9841 ttgtatgtaa gcgtttaaag catttgccca agttactgac cgttgccaaa aatcaatcaa
     9901 tgaatcaaat gatacatttt tcaaaacata tcccattgct tctttttcat cttttgacaa
     9961 aaagacataa aactttgtca ctatggctgg cactgacaag cctttcttta acaaatattg
    10021 aacaatgtaa tcatcgccat cataaagacc aacaatacat ctctttaaaa ggtaaacttc
    10081 cgaaagtgac ataatcctat caacattcca atcagaaaaa ccacaaatga aaaaggcatc
    10141 atccttgata cctctttcta tcatgtgatc tcttacttga ttttccgtaa actgcatgat
    10201 gtctaactca cataaaaatt gacttctacc tttttcatga gttcttataa ttgcaatcat
    10261 tatctactta ccctgatatt tcgacatatc cgtagtctga aaaaccacct tggctttcta
    10321 agtcaatatc tcgaccataa gcttcacaat caaaatagag ttccatattt tctttaccaa
    10381 caccttctga acctaattca ttaaaccagt attcgcctaa ttctcgtcta gttgtgacat
    10441 caggcagtaa acaacaatca ccaaaattaa aatcataatc tacaaagtct gaggcagtat
    10501 aacctgttac ctgatgcact gcttgaacaa gttcactatc aacattctct accagttcaa
    10561 caaattatta atcatctcaa tagaatcatg ttcttttagt aactgacaat ccgaatctgc
    10621 aataatatac tctaaatcat cttcttcacg aagccccaaa gctaacttaa gctcactcat
    10681 ttccacagga aaacaaacta acgtagctct accagttttt atatctctaa caattgcact
    10741 aacatccatt tttgacactc cttaattaaa aaaggagcaa gccattgact tgctctcatc
    10801 cttaatgaaa ttcttgtagt ttatgaccaa tcgctgacat agacttatga gccttattaa
    10861 tcatattatt ttggtagtag tatgatttca aatgttgttg aatcatgtcg accatataac
    10921 ctggtaaggt caattcttca cgttttttaa gtaagctatt taactctcca gctttttccc
    10981 atgactggtc atactgatga ctaatcagca gttctgatag ctcctgagta accactaaca
    11041 actttttatc tgcttctgaa cgtgtatttg acatttttct tttcctcttt ttcttttttt
    11101 atactcaata ccaataaatc aacatatgat agttggacac ctaattttca tcattttccc
    11161 tcataaaaaa gaacctctta aggttcatga atctaaaact aactgtttaa gcatctgaaa
    11221 tacctaataa ataatttgga gtagtattta atagtttaga tagctcaatt agttttgaaa
    11281 acttggttct cgctttccgt tctcccaatt tgaatatgct cctctattaa taccaattct
    11341 atcagcaagc tcttgttgtg ttaatttatt aagctgtcgt tgttttctta aacgatctcc
    11401 aagtttttcc atttacctta ccccttatga tttataagtt ggattttaaa tgatcccaga
    11461 aattaatcaa cttcttcatc tctaaacatt tcctttttca tcagaattct cttttccaaa
    11521 tgatatttag cagctaaacg aataactatc tctttttgct tttctaaagg ttgcataagc
    11581 aaaccaaact ttaaaagttt ccgtttaaaa tcagcaagtt cccttaactt atcttcgtag
    11641 tctttttgaa tttcataaac accaacataa ccaatcttaa tcaaatcata aatgtctatc
    11701 tgataatctc taagctcacc tgtttgaatc tcaggataat aaaattcacg atcaggaatc
    11761 attaatacca aagaatcaat gaccagctct aaattatttc tcgttgatat aaaataatta
    11821 aattcatttt ctaaaaacat ctacgccccc ttatctaaac ctagattata tcgaatagtt
    11881 tctaatattt tttcacctcg ttcattcact tcaccagaat taatgatcat ttgtagatta
    11941 tccccatcaa tcatactgtc atattcacta accatagcta gagaatcaga tacttgatga
    12001 atcaaccagc gaatagtacg ttcaatatta taagattctg gtctcgtgac aaatgttaga
    12061 ggttcaacac ctccaaacat catctgccac ttttgatcag ccataaatgc accatactta
    12121 ttttttccat cataaacttg aattttacta ttaatcaatc ctctcgcaat ttctcctaat
    12181 ggaataccag aaataaattc atctaccact gcattcgcct tagattgaga taatcggatt
    12241 tcataccgat tccatatttc aaatatttct aaagattctt caacagagat gccctctaat
    12301 ttagctaatt catacctttt ctcataaaag ttaaaataca tttcagactg tcgactacca
    12361 aaatataacg aaataccttg acgattctgt tcaatttctt ccatatcatt aaaatttaaa
    12421 gcaccaccac caatataatt ccatgttcgc aaactttcaa aagctaactc atgatgataa
    12481 tatttggcaa tcatatccga taaaagaaag tgttcatttt ctctatcctt acccagatac
    12541 aattcatcaa tagctaagtc aaaacgtgta acattcattt catctcgata agaacgtctt
    12601 aagtagatta gccaatctaa ccaagcaaaa ttttcttgtt ccataagtaa ttctaattgt
    12661 ctacatcctt gaccagatag ctgtaatgtt atttgatagt ttcctgtatc atgtttatct
    12721 gcataatcaa atatccaaat atctccacgt ttccaaatat ggttataatt catcaactta
    12781 gattcaactg atgaaaattc tttaaatcga caatgtaaaa aattccgaca aaaaaattcc
    12841 aaatctctaa cgctttttaa cgtaatcctg acatagtcaa ttgtcacttg taatcttgaa
    12901 ctatcattat cagtcaaata accaaaatgt gttttcattt cttgaaattt ttcaagagat
    12961 aattttttct taccagattc atattgagat aacatagctt gactaatacc tatacatttt
    13021 gcaaattctt tctgctttaa gcctgatttc ttcctaaatt tctttaaata cattggattc
    13081 atctattttc tccctaaata ttatcaattt ttagctattt tttgataaaa tataacctgt
    13141 ttttgctcgt tttataacct atttttgaaa cttgaaaatc cttgatacat atggggtttc
    13201 gggggtttta cttcgtagat ttttcaaatc ttacccccct attagaaatc gggggtttta
    13261 aaattgataa atccttctgt aaagccctag tgtgtgcgct gtgtccggcg tgtccgtttc
    13321 cgctacgcta cactacgcct acagctacac tagggcttta cagaaggata tttaaaaaaa
    13381 tacccttcat ctactattca cccttaaaat aattcaacaa caactctttc caactgccat
    13441 caaacttatc tttttgagtg agtaaactat tcaatataac tgcatcagaa tcagtcaata
    13501 ctactctttc atcttcacga ttaaaagtca tgtaaccatc tttttcaatc atatcaatta
    13561 aattttttat tttaccaaat gaaaaacctg ttttcttagc taaatcacca atactcatat
    13621 gattaatttc ctccatttcc tcttcaaaat caaagccaat acttccttta ggtaactcat
    13681 tgtcagacgt tttttctaca aattttctca atgattcatc tgaaataata tccttggaaa
    13741 ccaaagtatt ttcaagcgga tcaaatggat tatcatgacg tgagattttc gcaaattcat
    13801 cataaaatga aaatttctta gttagcaaag gagcataaaa ctctctcgct acctcgccaa
    13861 aaacagcaga atagccacga ccatacacac ggtgacctga tagaaattta atatacctga
    13921 actctttatt ccgattttca tccccaaaaa gcatcatata accaccatca tcaaggcgac
    13981 caacagaaat atggtgcatc atatttgacc tgatttttgt tggtaaatca tctgcggatg
    14041 gcttttgcat ggcaataatc gcattacagc ctacttgacg gccaagtaga atatactgtg
    14101 taaaggcatt ctcaacaatg tctctttcct gatacgataa cgaagacatc aaggcattat
    14161 attcatcaca aataaaaaaa tatggttcta atccgtaatc ataaaatttc cccatatctt
    14221 tatgccctaa acgtttcatt tccttacgaa taaagtcata gcgtgcatac atgattgtaa
    14281 ttgcattctc aaatttagca ataatatcta ctttttcaaa aacaattctt cctcgaaaag
    14341 caggtaaatc agccattgtc acaaaatcag ctcgcttagg atcacatata tccgcaacgc
    14401 caatagttgc aagacatttt aaaattgatc taagcaaaac agtcttaccg ccaccagtcc
    14461 cacccgcaac aagcaaatga ggatcattga taaaatccca ataataacca ttcatcagct
    14521 taatgccttt atccttttcc catacaacat cattaaccgt tatacgagcc agaaaggcgg
    14581 aataagctaa tttataaatc ttaaacctag gatcatcagt tttttccata aaatccataa
    14641 aaaaagtatc ttcaagttca cctccaatat ctttgaaacg cttttgaaat ttgtttcctg
    14701 ccatttcaaa ggagacactt aaatcaaact taccttgttt taaataaact tttggaaaac
    14761 taactttctg cttcttatta acttttttac gtttttcata aacaaaacca ttttc
//
LOCUS       DATWEK010000037        13895 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.037, whole genome shotgun sequence.
ACCESSION   DATWEK010000037 DATWEK010000000
VERSION     DATWEK010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13895
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.037"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..755)
                     /locus_tag="VCR92_001477"
     CDS             complement(<1..755)
                     /locus_tag="VCR92_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEP4268534.1"
                     /translation="MLTSKHHNLNKLVWRYGLTSAAAVLLAFGGGASSVKAEVSTAAM
                     TKEERQQEIEKIKEDIKKEYPKASEEKFWESSFWGRRYFNEQEYLKSLQSFTEQRLQD
                     IVNLIEKGATKGDKGDAGPKGERGPAGPQGPVGPKGEAGKVGAQGPKGDPGAPGKDGA
                     KGEKGDKGDTGERGEKGDIGATGAQGPQGEAGKDGAPGEKGDKGETGAQGPAGPQGEA
                     GKPGEQGPAGPQGEAGKPGEKAPEKSPEGEAGQP"
     gene            1137..1619
                     /gene="nrdI"
                     /locus_tag="VCR92_001478"
     CDS             1137..1619
                     /gene="nrdI"
                     /locus_tag="VCR92_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEP4268535.1"
                     /translation="MPQITLVFISLSGNTLSFVKRLSLYLADNYDYHVKQINIKDLKH
                     ETFPVKEEFVAILPTYLEGGNGVDSGEVEILTTPLGEFIAAHGNAQRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPLLGDFELRGTPDDISRLAQVIMEASSRHSSNDTQTLPNS
                     "
     gene            complement(2013..2831)
                     /locus_tag="VCR92_001479"
     CDS             complement(2013..2831)
                     /locus_tag="VCR92_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEP4268536.1"
                     /translation="MTKVLTLNTHSWMQANTLKKLVALAEHILAEKYDIICLQEINQL
                     IESELATDLPRYQALSGTPNIHKDHFALLLIHYLQKRGQHYYWSWAYNHIGYDIYQEG
                     VAILSKQPIHVSDILVSAMADETDYHTRRSLIAKTTLDGKEVAVVNVHLSWFDKGFLG
                     EWEKLEKELLTLNCPLLLMGDFNNPTDQDGYQVMMGSPLDLQDSHKVADHVFGDHSIV
                     ADIDGWQGNKEALKVDHVFTSKDFIIRSSKITFEGGDAPVVSDHYGLEVTLGWR"
     gene            complement(2914..5100)
                     /locus_tag="VCR92_001480"
     CDS             complement(2914..5100)
                     /locus_tag="VCR92_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEP4268537.1"
                     /translation="MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMI
                     NHESAFLASLGNIIAQIGWAVIVNLHLLFALAIGGSWAKERAGGALASGLAFVLINRI
                     TGAFYGVSSAMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIA
                     SSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMALKAGLGMDVINFVWVSILFAVIMYFIADMMIKKMHLATAGR
                     LGNYDADILGDHNTQATPTQVADSNSQVVQIINLLGGAGNIDDVDACMTRLRVTVKDP
                     AKIGAEDDWKKAGAMGLIQKGNGVQAVYGPKADILKSDIQDLLDSGAVIPEVNMSQLT
                     SKPTPAKDFKHVTEEVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTHGNIYAPVA
                     GLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVA
                     DLAAIKSAERETTIVVAFTNTTEIQDVTLTSLGAQPAKTKVATVEL"
     gene            complement(5457..6206)
                     /locus_tag="VCR92_001481"
     CDS             complement(5457..6206)
                     /locus_tag="VCR92_001481"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEP4268538.1"
                     /translation="MQQYFIKGKAEKEVTITDKDTIKHMFQVMRLADKAEVVLVFDDG
                     VKYLAKVTNSMAHELEIIEALPDQVELPVKVTIASGFPKGDKLDTIAQKVTELGASAL
                     WGYPADWSVVKWDGKKLAKKEDKLAKIVLGAAEQSKRNRVPEVHLFEHKAEFLKSLSG
                     FDHIFVAYEETAKAGQLATLAREVKEVKPGAKILFIFGPEGGISPTEITQFEAAGAIK
                     VGLGPRIMRAETAPLYALSALSYALELQASK"
     gene            complement(6206..7159)
                     /locus_tag="VCR92_001482"
     CDS             complement(6206..7159)
                     /locus_tag="VCR92_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEP4268539.1"
                     /translation="METWQEVTVHVHRDAQEAVSHVLIETGSQGVAIADSADYIGQKD
                     RFGELYPDVEQSDMIAIIAYYPSSTNLADVIATINEQLAELASFGLQVGQVTVDSQEL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKM
                     SLFALEQILRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQENIDLNQ
                     GTDNIHVAAGDLLKGVSQEADVIVANILADILVLLTDDAYRLIKKEGYLILSGIISEK
                     LDMVLEAAFSAGFFLETHMVQGEWNALVFKKTDDISGVIGG"
     gene            complement(7229..7699)
                     /locus_tag="VCR92_001483"
     CDS             complement(7229..7699)
                     /locus_tag="VCR92_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEP4268540.1"
                     /translation="MAKYGFLSVLEEEMDKHFQYDYAMDWDKKNHAVEVTFVLEAQNK
                     EAIKTIDDSGEVTQDDIVFEDYVLFYNPAKSQFDAADYLVTIPFDAKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKVDFGLEWNAQAFEEGQQGLEEAASYAYPRY"
     gene            7900..9657
                     /gene="pabB"
                     /locus_tag="VCR92_001484"
     CDS             7900..9657
                     /gene="pabB"
                     /locus_tag="VCR92_001484"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEP4268541.1"
                     /translation="MHRKTIIDFKELGQRYLFDEPLVELVAKSLDQVGPVIENVQHYQ
                     QLGYYVVGYLSYEAAAFFDNALQTHNDRLGNEYLAYFTVHKTCQKKDLPLDYDGITIP
                     NQWVSATQKEAYQKAIETIHREMQQGNTYQVNYTLQLTQELNAADSLAIYNKLVVEQA
                     AGYNAYIAHDDFAVISASPELFFKQEGNRLTTRPMKGTTKRGVNSWLDQQEHDWLQAD
                     GKNRSENMMIVDLLRNDMGKICQTGSVCVDRLCEVERYSTVWQMTSTIVGDVKADCDL
                     IDILTALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICLPDGRRFFNVPIRTI
                     QLSHNQATYGVGGGITWQSKWEDEYEEVHQKTAFLYRHKQIFDLKTTAKVKHKKIAFL
                     EQHLNRLKEAATYFAYPYDEKALQKQLSTYLENKDNAAYRLMIRLSKDGKISLSDQPL
                     EPLSADFLTAQLSLQKKDVTASPFTYFKTSYRPHIEQKSYEQLFYNQAGQLLETSIGN
                     LFVQLGRTLYTPPVVVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGGNAVRGL
                     YPLNLKLTHLDALLAKSQA"
     gene            9690..10256
                     /locus_tag="VCR92_001485"
     CDS             9690..10256
                     /locus_tag="VCR92_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEP4268542.1"
                     /translation="MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKANA
                     LVLSPGPGWPKEANQMPKLIQDFYQTKPILGVCLGHQAIAETLGGNLRLAKRVMHGRQ
                     STIETQGPASLFRSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPL
                     FGLQFHPESIGTPDGMTMIANFIAAIPR"
     gene            10289..11557
                     /locus_tag="VCR92_001486"
     CDS             10289..11557
                     /locus_tag="VCR92_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEP4268543.1"
                     /translation="MPDHLALRMRPKTISEVIGQKHLVGEGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTRYAFRTFNATIDSKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLENGTIIMIGATTENPFFSVTPAIRSRVQIFELEPLSNEDIKTAIQ
                     LAISDKERGFPFLVTIDDEALDFIVTATNGDLRSAYNSLDLAVMSTSPNEDSSRHISL
                     ETMENSLQRSYITMDKNGDGHYDVLSALQKSIRGSDVNASLHYAARLVEAGDLPSLAR
                     RLTIIAYEDIGLANPDAQVHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYL
                     AMDAALADLRTSGNLPIPRHLRDGHYAGSKDLGNAKDYLYPHAYPEKWVKQQYLPDKL
                     VGHHYFEANETGKYERALGSNKERIDKLSD"
     gene            11646..11842
                     /gene="ssrS"
                     /locus_tag="VCR92_001487"
     ncRNA           11646..11842
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="VCR92_001487"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            11843..11915
                     /locus_tag="VCR92_001488"
     tRNA            11843..11915
                     /locus_tag="VCR92_001488"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11876..11878,aa:Lys,seq:ctt)
     gene            12056..12496
                     /locus_tag="VCR92_001489"
     CDS             12056..12496
                     /locus_tag="VCR92_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP4268544.1"
                     /translation="MKIIEYKGNYRDDLIFMVLEAKNALRRIPSINPDLLTIETSYLE
                     KGDCFWLAVNEESRVIGSIAYSSIPKTNEVFLHRLFIKPSLKHQGIGSQLLTFAEDYL
                     RKIGKSHVRIHLGQPKEQWFESYRFYPKHGYQFYDDTHLIKKLI"
     gene            12551..13057
                     /locus_tag="VCR92_001490"
     CDS             12551..13057
                     /locus_tag="VCR92_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEP4268545.1"
                     /translation="MKIAIIGHSGSGKSTLARFLGQHYHCEVVHLDQLHFSSNWQERS
                     DHDMIADLSTCLLKQDWIIEGNYANCLYEERMSEANHIIYVNFSRFHCVYRAFKRYLN
                     YRGKTRPDMADNCQEKFDVAFVKWILLDGRSRNQLKKYQSVIQKYPHKTIVLTNQKQL
                     NHYMNTIN"
     gene            13306..>13895
                     /locus_tag="VCR92_001491"
     CDS             13306..>13895
                     /locus_tag="VCR92_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin"
                     /protein_id="HEP4268546.1"
                     /translation="MKKTKLIFSFTSIFIAIISRPVFGLEVDNNSLLRNIYSTIVYEY
                     SDTVIDFKTSHNLVTKKLDVRDARDFFINSEMDEYAANDFKAGDRIAVFSVPFDWNYL
                     SKGKVTAYTYGGITPYQKTSIPKNIPVNLWINRKQISVPYNEISTNKTTVTAQEIDLK
                     VRKFLISQHQLYSSGSSYKSGKLVFHTNDNSDKYSL"
BASE COUNT         3946 a         3187 c         2693 g         4069 t
ORIGIN      
        1 ggttggcctg cttcgccttc tgggctcttt tctggagctt tttcacctgg tttgcctgct
       61 tcaccttgtg ggcctgctgg accttgctca cctggtttgc ctgcttcacc ttgtgggcct
      121 gctgggcctt gtgcgccagt ttcacctttg tcaccctttt cgcctggagc tccatcttta
      181 ccagcttcac cttgtgggcc ttgtgcgcca gttgctccga tgtcaccttt ttcaccgcgc
      241 tcaccggtat cacctttgtc gcctttttca cctttggcgc cgtctttacc tggggcacca
      301 ggatcacctt taggaccttg ggcaccaacc ttacctgctt cacctttagg tcctaccgga
      361 ccttgtgggc ctgctgggcc gcgctcgcct ttaggaccag catcgccttt gtcacctttt
      421 gttgcacctt tttcaatcag atttacaata tcttggagtc tttgctcagt aaaactttgt
      481 aaagatttta gatactcttg ttcattaaag taccttcttc cccaaaagct actctcccaa
      541 aatttttcct cagacgcttt tggatattct ttcttaatgt cttctttaat tttctcaatt
      601 tcttgttgtc tctcctcctt cgtcatagcc gcagtagaaa cctcagcctt aacgctgctt
      661 gccccgcctc caaaggctag aaggacggca gcggctgagg ttagcccgta gcgccagact
      721 agtttgttga gattgtggtg ttttgatgtc aacatatgtt gttctctctt tctttattag
      781 atggtgtgtt ttagataaaa ataacatggt agctagacct gattatttat aatagtatta
      841 taatagagtg tgaaaacgat tgtaaagttc tcttttgttg ttcatctttt agattttgac
      901 tgatcactct tttgtggaga tcagagggct actttggcac ttgcctgcct cgtttttaag
      961 tcgagggcat ccggatcctt tctttaaggt cactcttttt tgaaatgtta ctttttttga
     1021 ccgcttgtac cttcttgtct ggttggatat cgctaggttt cttctttact tgtttgttgg
     1081 tcttgattgt ggtaagctta tgaagaaacc ttgtaggata aaaaaaggag acacttatgc
     1141 ctcagattac tcttgttttt attagcctca gtggcaacac ccttagcttt gtcaagcggc
     1201 tatcccttta tttagcagac aattacgatt accatgtcaa acagattaac attaaagatt
     1261 tgaagcacga gacttttccc gtcaaggaag agtttgtggc gattctaccc acttatctag
     1321 aaggcggaaa tggcgttgac tctggtgagg tggagatcct caccactcct ttaggagagt
     1381 ttattgccgc ccatggcaac gcccagcgtt gtcttgggat tattggttca ggcaacaaaa
     1441 actttaacca tcagtattgc ctgacagcca aacagtatgc caaacgcttt ggctttccac
     1501 tgctaggtga ttttgagctg cgagggactc ctgatgacat ttcgcggtta gcccaggtca
     1561 tcatggaggc cagctccaga cactcgtcta acgacacaca gacactgcct aacagctaga
     1621 ccgtctatag atgatcatag ctgttttaaa aaagagcact tttaggacac caactaggga
     1681 ggtctcttac cctacgcctt gcgatttctc agcctttgaa aagagcgatc acagtgcttc
     1741 ttggggcttg ggatcactcc aagcgctcct agaaataccc ctatgcagac tttagcaagg
     1801 caactgaacg cttggcggta ctttctgtga agctcagatg gttggtggca aaaaagccct
     1861 ggttttttag ggttactgac atgactaaag aggtctaacc agctctacct tgagctcgtt
     1921 agacctcttt gtgttctcct aatcccccta gacgatcgca gtttcttatg tgtcttggct
     1981 tctcctatgt ggtgtgcctg ttagcacatg ctctaacgcc agcctaatgt cacttctaaa
     2041 ccgtagtggt cactgacgac tggcgcatct ccgccttcaa aggtaatctt agaagatcgg
     2101 atgatgaagt ccttgctggt aaagacatgg tccaccttga gggcttcttt gttaccttgc
     2161 cagccatcaa tatcagccac gatgctatga tcaccaaaca catggtcagc aaccttatgg
     2221 ctatcttgta ggtctagggg gctacccatc atcacttgat aaccgtcttg atccgttgga
     2281 ttgttaaaat ctcccataag tagcaaggga cagtttagtg tgagcagttc tttttctaat
     2341 ttctcccact cccctaaaaa ccctttgtca aaccaagata ggtgcacatt gacaacagcg
     2401 acttctttgc catctaacgt ggttttggct atgagtgagc gtctggtgtg gtagtctgtt
     2461 tcatcagcca tcgctgacac gagaatatct gaaacatgaa taggttgttt tgataagatt
     2521 gccacgcctt cctggtaaat gtcatagcca atatggttat aagcccaaga ccaataatag
     2581 tgctgccctc gtttttgtaa ataatggatc aagagcaggg caaaatggtc tttatgaatg
     2641 tttggtgtcc ctgaaagagc ttgatatctt ggtaaatctg tggccagctc gctctcgatt
     2701 aactgattga tttcttgcaa gcaaatgata tcgtattttt cagctaaaat atgctcagcc
     2761 aaagcaacta attttttaag agtgttggct tgcatccacg aatgggtatt cagtgttaat
     2821 accttggtca ttaatcctcc tttataagac aagaagagcc atagggccta aaccagctat
     2881 ggctattacc tatcactatc tcgtgatgtt ttgttaaagt tctacggtag ctactttagt
     2941 cttagcaggc tgagctccta aagatgtcaa ggtcacatct tggatctctg ttgtgttggt
     3001 aaaagcaaca acaatggttg tttcacgctc tgctgattta atagcagcaa gatctgctac
     3061 gactaatagg tcacctgcat gaacccgttg tccttctgag actttgactg aaaaaggcac
     3121 accatttaag gcgacggtat caagtcccac gtgcaccagc acttcaagac cattatctgt
     3181 cagtaaacca aaggcatgct tggtcggaaa gacactggtc acaaggccag ctactggtgc
     3241 atagatatta ccatgggttg gttcaaccgc aaacccatct cccatcatct tagccgcaaa
     3301 cacctggtct ttcacacctg tgattgggag aaccatcccg tctgccactg atagcacttc
     3361 ttctgtcacg tgtttaaaat cttttgcggg agtcggtttg ctagtgagct gtgacatgtt
     3421 gacttctgga ataacagccc ctgagtccag caaatcttga atatctgatt tcaaaatatc
     3481 tgctttaggc ccatagaccg cttgaacgcc gttgcctttt tggatcaagc ccatagcgcc
     3541 agcttttttc caatcgtcct cagcgccaat cttagcgggg tctttgaccg tcactcgtaa
     3601 gcgcgtcata caagcatcaa catcatcaat attgcctgcc ccaccaagga gattaatgat
     3661 ttgtacgact tgagagttgc tatctgctac ttgggtaggt gttgcttgag tgttatggtc
     3721 acccagtata tcggcatcgt agttgcctaa acggccagct gtcgcgagat gcattttctt
     3781 gatcatcata tccgcaataa agtacatgat aactgcaaag aggatagaaa cccaaacaaa
     3841 gttaatcaca tccatgccta gacctgcttt aagggccata ggggtacggg ttagtagctc
     3901 aatgttccca aatgagtgaa cacggagatt cacaaggtct gccatggcaa atgaagctcc
     3961 ttgaacaagg gcatagacga tgtaaagtgg cattgctgca aacataaata ggtactcaag
     4021 tggctcagtt acccctgtca aaaagaccgc tgccgctgct gagatgaaca tcattttgta
     4081 tgtatgtttt ttatcggcat ccacattacg gtacatggct aaggcaaccc ccatcaatgt
     4141 tccggtagct ccaatcattt gtcctacctt aaagcgagct ggagtcacac tatccattaa
     4201 gtgactatag gctgaagcgt ctgatccttt aaggtgaaca aggtcagtta cccaagcaag
     4261 ccacaaaggg tcttgaccaa atacttttgt ccccgctgct gcacctgtca tgacctcata
     4321 agttccacca agagctgtat agttcattgg aatcgtcaac atgtggtgaa gaccaaatgg
     4381 caacaagaga cgttccaagg taccatatag gaatggggct aggattggag ctgaatcttg
     4441 tgaagaggca atccacatcc caaaactgtt aatcccagac tggatcaccg gccaaacaac
     4501 aaccaaaata agggctacaa aaatagaacg taaaataacg acaaacggta caaaacgctt
     4561 cccattaaag aaggtcaaaa cttcaggaag tttacggtaa ttatagtatt tgttataggc
     4621 cgttgctcct acgaaccctg caataatccc aacaaaaacc cctgtgttta aagctggaga
     4681 ctccaagaca ctggtgaaat aatctttaac gatcatttga gtgccaagga ggcttgtgat
     4741 ttttgcttct ggatcagcta gcatagcact agacacgcca taaaaagcac ctgttatccg
     4801 attgatcaag acaaaagcaa gccctgaggc aagggcccct ccagctcttt ctttagccca
     4861 actaccacca atggccaagg caaatagcaa atgaaggtta acaataacag cccaaccaat
     4921 ttgagcgata atgttgccta gagatgccaa aaatgctgat tcgtggttaa tcattggaat
     4981 agagtttccg atactgatca ttaaaccagc cgctggcatg acagcaataa cgaccataag
     5041 acatttccca aatttttgcc aaaattcgaa acgaaacagt tgcttgaatg atgttttcat
     5101 tctatctctc ctttattatc cccttttagc catagctgcc cttaaggcgc ttttgtgaca
     5161 caatgatata gactgcaact cagtgatgca atcgtttgca ttgatctgat acctttatta
     5221 tactagcctc gcaacaattt gtaaagcgtt ttcttagaca gatgttagtc gtttttcttc
     5281 attaaatggt agtgtaactt accaaaaaga taacaagagc ccatttcctt ttttggtgat
     5341 gagaccatca acgctcttcg aaaaaacaag aagcaataaa aaaaggccgt tgacacaatc
     5401 gtgaactgcc tgttcgtttc tttagcctct tctttctaaa gtaagcagca gcttacttat
     5461 tttgatgcct gcaattccaa agcataacta agagcactta aggcatatag cggcgctgtc
     5521 tctgctcgca taatgcgagg gcctaagccc accttgatgg cacctgctgc ctcaaactga
     5581 gtgatttcag ttggggaaat tcccccttct ggtccaaaga taaagaggat ttttgcccct
     5641 ggcttaactt cttttacttc acgcgccaag gtcgctagct gacctgcctt agctgtttct
     5701 tcgtatgcaa cgaaaatatg atcaaagcca gaaaggcttt ttagaaactc tgctttgtgc
     5761 tcaaaaaggt gaacttcagg caccctattt cgtttgctct gctcagccgc tcctaataca
     5821 atcttagcca atttgtcttc ttttttagct aattttttgc catcccattt gaccactgac
     5881 cagtctgctg ggtagcccca tagcgcactg gctcccaatt cagtcacttt ctgtgcaatc
     5941 gtgtctaact tatcgccttt aggaaatcca gaagcaatag tcaccttaac aggcaattcc
     6001 acctgatctg gcaaagcctc tataatctct aactcatgag ccatactatt ggtcaccttg
     6061 gctaaatact tcaccccatc atcaaagacc aagacaactt cagccttgtc agccaagcgc
     6121 atcacttgaa acatgtgctt gatggtatct ttatcggtaa ttgttacctc tttttctgct
     6181 ttgcctttaa taaaatactg ttgcattagc cgccaatcac tcctgagata tcatctgttt
     6241 ttttaaagac aagggcgttc cactcacctt gaaccatatg cgtctcaagg aagaatcctg
     6301 cgctaaaggc agcttccaga accatatcca atttctcaga aatgatgcct gataagataa
     6361 ggtaaccttc ctttttgatc aaacggtaag catcatcagt caataagact aagatatccg
     6421 ccaagatatt ggctacaatc acatccgctt cttggctaac cccttttaaa aggtcaccag
     6481 cagccacatg aatgttgtct gttccttgat ttaaatcaat gttttcttga gccactcgaa
     6541 cagctacatc atctaagtca taagcgtaga tggttttagc acctagtaag gaactggcaa
     6601 tcgagaggac acctgatccg gtccctacat cgataactgt ctcaccacca cgaaggattt
     6661 gttctagagc aaaaaggctc atcttagttg tgggatgtgt ccctgtccca aatgccattc
     6721 caggatctaa tttaataacc ttttccccag cagaagcgtc ataatccgtc caactaggga
     6781 caatagttaa atcatgcgtg atgcgagctg gttcatagta ttttttccaa ttgtctgccc
     6841 agtcttcctc agctaattct tgactatcca cagtaacctg accaacctgt aacccaaaac
     6901 tagctaactc cgctaactgt tcattaatgg tcgcaataac atccgccaaa ttagtgctac
     6961 ttgggtaata ggctatgata gctatcatgt cagactgctc cacatctggg tataactccc
     7021 caaagcggtc cttttgccca atatagtctg cgctatccgc gatagcgacc ccttggctgc
     7081 ctgtctcaat caacacatgt gaaacagcct cttgcgcatc acgatgcaca tgaaccgtca
     7141 cttcttgcca cgtttccata agtatgtcct ttctattttg accttttggt tattgtccta
     7201 atggtgttac accatctcgt gtgtcacctt agtaccttgg gtaagcgtaa cttgctgctt
     7261 cttctagtcc ttgttgacct tcttcaaaag cttgcgcatt ccattccaag ccgaaatcaa
     7321 ccttgctgtc atctgctaag aaatccatca aatcgctgtg cccttcaata gcaacatcgt
     7381 tgagaaattg cgcaaagtaa gctaagaatt cacgagaaaa gcccttttta gcgtcaaaag
     7441 gaatagtaac caaataatct gctgcatcaa attgagactt ggcagggttg taaaagagca
     7501 catagtcctc aaagacaata tcatcttggg tcacttcgcc actgtcgtca atggttttta
     7561 tggcctcttt attttgagct tctaacacaa aagtcacttc aaccgcatga tttttcttgt
     7621 cccaatccat agcataatca tactgaaaat gcttatccat ttcttcttct aatactgata
     7681 aaaagccgta ttttgccatc tttttttata cctaatcttt ctaactgttg ctgtatagag
     7741 ctttgtaaga cctcattagt ttacttactt tgacatgctg agcgtactgt tataactttt
     7801 attaactgaa ttataacata tttgactaat attgaccata agagaaggtc ttaatggctg
     7861 gatcacctct agcaaccgct tttatgatat aatttgggta tgcatagaaa aacgattatt
     7921 gatttcaaag agctcgggca acgctatctt tttgatgagc cattagtaga attggtagcc
     7981 aagtccttag atcaggtcgg tccagtcatt gaaaacgtac aacactacca acagctgggc
     8041 tattacgtgg tgggctatct cagttatgaa gcagctgctt tttttgacaa tgccttacaa
     8101 acccataatg acagactagg caacgagtac cttgcctatt ttacagtgca caaaacctgt
     8161 caaaaaaaag acctacctct tgattatgac ggcattacta tccctaacca atgggtcagc
     8221 gcaactcaaa aagaagccta tcaaaaagcc attgaaacca ttcaccgtga gatgcaacag
     8281 ggcaacactt atcaggttaa ctacaccctt caattaactc aggaactcaa tgcagctgac
     8341 agcttagcca tttacaataa actcgtcgtt gaacaggctg ctggctacaa tgcctatatc
     8401 gcccatgatg actttgctgt tatttcagct agtcctgagt tgttctttaa acaagagggc
     8461 aacaggttaa ctactaggcc tatgaaaggc accaccaagc gtggggttaa tagctggctg
     8521 gatcaacaag aacatgactg gctccaagct gacgggaaaa accgttctga aaacatgatg
     8581 attgtggatt tgctccgcaa tgacatggga aaaatttgcc aaacaggcag tgtttgtgtc
     8641 gataggctct gtgaggtcga gcgatactct accgtctggc aaatgacctc aaccattgtt
     8701 ggtgacgtca aagcggactg tgacctgata gacattctca cagctctctt tccttgtggc
     8761 tctatcacgg gggctcctaa agtctccacc atggcaatta tcacatctct ggagccaaaa
     8821 ccaaggggga tttattgtgg aagtattggc atttgcctac ctgatggtcg ccgtttcttc
     8881 aatgttccca ttagaaccat ccagctcagt cataatcaag ctacttatgg tgtcggaggc
     8941 ggtatcactt ggcaaagcaa gtgggaagac gaatacgagg aagtccatca aaaaacagct
     9001 tttctctatc ggcacaaaca aatctttgac ctcaaaacaa ccgccaaggt gaaacacaaa
     9061 aaaatagcct tccttgagca acacctcaat cgccttaaag aagcagccac ttattttgct
     9121 tacccttacg atgagaaagc tttgcagaaa caactgtcaa cctatttgga aaataaggat
     9181 aatgctgcct accgcttgat gattcgttta tccaaggatg gaaagattag cctctctgat
     9241 caacccttgg aacctttgtc agccgatttt ctgacagctc aactctcttt acagaagaag
     9301 gacgtgacag cttcgccttt tacctacttt aagaccagct accggcctca tattgagcaa
     9361 aaatcttatg aacagctatt ctataaccaa gcggggcaat tattggaaac gtccattggc
     9421 aatctctttg ttcagctggg tcggaccctc tacacaccac cagttgtggt aggtatttta
     9481 ccaggacttt ttcgccaaga gctgctagct actggtcaag ctcaggaaaa agaggtgaca
     9541 ctagctgatt taaaagaggc tagcgctatt tttggaggaa atgctgtccg tggcctctat
     9601 cctctcaacc ttaagcttac tcaccttgat gccctcttag ctaagagtca agcctaaact
     9661 gccactcatc ttttgttatt aaggaaccta tgatactctt aattgataat tacgattcat
     9721 ttacctacaa cctcgcccaa tatttaagtg aatttgacga gacgattgtc ttgtataacc
     9781 aagacccaaa cttatatgac atggccaaaa aagctaacgc tctagtcctc tcacctggtc
     9841 ctggttggcc caaggaagcc aaccaaatgc caaaactcat tcaagacttt taccaaacaa
     9901 aacctatctt aggagtgtgt ctgggacacc aagctatcgc tgaaacccta gggggaaact
     9961 tacgcttggc taaacgtgtc atgcatggga gacaaagcac cattgaaacg caaggccctg
    10021 ctagtctttt tcgctccctg ccacaagaga tcaccgtcat gcgttaccat tccatcgttg
    10081 tggatcagtt accaaaaggt tttagcgtaa ctgctagaga ctgtgacgat caagaaatca
    10141 tggcctttga acaccacacc ctgccacttt ttgggctaca atttcaccca gaaagcatcg
    10201 gaactcctga tggcatgacc atgatcgcca acttcatcgc agccattccc cgttaatctc
    10261 atcccccaaa agaaagaagg acagttacat gcctgatcat ttagcgctca gaatgcgccc
    10321 caaaaccatt tcagaggtca tcggacaaaa acaccttgtt ggcgaaggca aaatcatccg
    10381 tcgcatggtg gaagcaaata gactatcgtc catgatcctc tatggccctc caggaatcgg
    10441 taaaacttcc attgcttctg ctattgctgg tactactaga tatgcctttc ggacctttaa
    10501 tgccaccatt gacagcaaaa aacgtctcca agaaattgcg gaagaagcta aattttctgg
    10561 tggcttggta ttattactag acgagattca tcgccttgac aagacaaaac aagattttct
    10621 tttaccttta cttgagaatg gcaccattat catgattggc gcaaccactg agaacccctt
    10681 cttttcagtg acacccgcta tcagaagcag ggtccagatt tttgaattgg aaccactttc
    10741 taacgaggat attaaaacag ccattcagct agcaatttcc gacaaagaac ggggatttcc
    10801 ttttttagtg acaattgatg atgaggcgct agatttcatt gttaccgcca caaatggaga
    10861 cctacgatct gcttataatt ccttggatct agcagtcatg tctacttctc ctaatgaaga
    10921 tagtagccgt catattagtc tagagacaat ggaaaatagt ctgcagcgta gttatattac
    10981 catggataaa aacggggacg ggcattatga tgttttatct gccttacaaa aatccattag
    11041 aggttctgat gtcaatgcta gcctgcacta cgccgctcgt ttagtagaag ctggagactt
    11101 gcctagttta gcaagacgat tgaccattat tgcttacgaa gatattggtt tagccaaccc
    11161 tgacgcccaa gttcataccg tcaccgcact agatgccgct caacgcattg gttttccaga
    11221 agctcgtatt cttatcgcta acgtggtcat tgatttggct ctatcaccta aatccaattc
    11281 agcttattta gctatggatg cagctttagc tgatttgaga acatcaggta acctccccat
    11341 tccaaggcat cttagagacg ggcattatgc tggcagtaag gacctaggca atgccaaaga
    11401 ttacctctac ccacacgcct accctgaaaa atgggtcaaa caacaatacc taccagataa
    11461 attagtagga catcattatt ttgaagccaa tgaaaccggt aaatacgaac gcgcacttgg
    11521 ttcaaataaa gagcgtattg ataagctctc agactgactg ctagttttaa aaatcgcaac
    11581 cgatttcaaa aatcgataat tttgcttgaa aaaattttaa aaagtggtat tataaaagta
    11641 cagaaacatt gctgtggcat acgaatccac atctaagtgt tgaccgacta tttctttgta
    11701 ttttcgggaa acaaagaccc tttctagtct gcaagccgtt tcacgcggac gcaacttcca
    11761 agaaagagcg cgttacccac ctgcttatac tgcgcgggct caatacaaaa acgtggatca
    11821 ccggtgccaa tacagcattc ttgcctcctt agctcagttg gtagagcagt agactcttaa
    11881 tctatgggtc acaggttcga gccctgtagg gggtatacaa ctatacatga aaaaaccttt
    11941 gtttaaaggc tttttttgct tgtcagaaga ggatttgttc catcatttat ccccgcagta
    12001 atttttttat ggtatgatac caattaaagc gcttaagatt aaggtggaga ctgttatgaa
    12061 aataattgag tacaaaggaa attacagaga tgacctcatt tttatggtct tggaagcaaa
    12121 aaatgcctta aggagaattc ccagcattaa cccggatctt ttgacaattg aaacaagtta
    12181 tttggaaaaa ggggattgtt tttggctagc ggtcaatgaa gaaagtcgtg ttattggctc
    12241 aatcgcttat tcttctattc ccaaaacaaa tgaggtcttc ttgcaccgtc tcttcatcaa
    12301 accaagctta aaacatcaag gcattggcag tcaacttctg acgtttgcag aagattatct
    12361 aaggaaaatc ggcaagagtc atgttcgtat ccacttaggt caacctaaag aacaatggtt
    12421 tgagtcttat cggttttatc ctaaacatgg ttatcaattt tatgatgaca cgcatctcat
    12481 caagaaacta atctaaacac atttcatacc ctttatagtc atttcatacg tcatttttag
    12541 gaggtatcca ttgaaaattg ccatcattgg acatagtggc tctggaaagt caaccttagc
    12601 acgattttta ggtcaacatt accattgtga ggtggtccat ttagaccaac tacacttctc
    12661 atcgaactgg caagaacggt cagatcatga catgatagct gatttatcaa catgcctgct
    12721 caaacaagat tggattattg aggggaatta tgccaattgt ctctatgaag agcgcatgag
    12781 tgaggctaat cacattatct atgttaattt cagtcggttt cattgtgtct atcgagcatt
    12841 taagcgttat ttaaactata ggggaaaaac gcgtcctgat atggctgaca actgtcagga
    12901 aaaatttgac gttgcgtttg tgaaatggat tctactagat ggacgttcaa gaaaccaatt
    12961 aaaaaaatac caatccgtta tccaaaaata ccctcataaa accattgtct taacaaatca
    13021 aaagcagctc aatcactata tgaatacaat caactaatta gagtgaaaaa ctaaaatagc
    13081 cacgggtaac ccgggctatt cagactgaaa gcctttgttt aaaggctttt ttgcttgttt
    13141 cataactaat cggcttaatt aaaagcgtca atccactttt agtatcatgt ctcaattttc
    13201 atttgatagt cagcaagtat atctacaaaa ttgttaatga ttatttcttt tgaaagtgtt
    13261 atattaaaac ataataaaat aataactcct gaaaagaggc tatttatgaa aaaaacaaaa
    13321 cttatttttt cttttacttc aatattcatt gcaataattt ctcgtcctgt gtttggatta
    13381 gaagtagata ataattccct tctaaggaat atctatagta cgattgtata tgaatattca
    13441 gatacagtaa ttgattttaa aaccagtcat aacttagtga ctaagaaact tgatgttaga
    13501 gatgctagag atttttttat taactccgaa atggacgaat atgcagccaa tgattttaaa
    13561 gctggagata gaatagctgt gttctccgtc ccatttgatt ggaactattt atcaaaagga
    13621 aaagtcacag catatacgta cggcggaata acaccctacc aaaaaacttc aatacctaaa
    13681 aatatccctg ttaatttatg gattaataga aagcagatct ctgttcctta caacgaaata
    13741 tcaactaaca aaacaacagt tacagctcaa gaaattgatc taaaggttag aaaattttta
    13801 atatcacaac atcaattata ttcttctggt tctagctaca aaagtggtaa attagttttt
    13861 catacaaatg ataattcaga taaatattct ctcga
//
LOCUS       DATWEK010000038        13320 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.038, whole genome shotgun sequence.
ACCESSION   DATWEK010000038 DATWEK010000000
VERSION     DATWEK010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13320
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.038"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            9..2171
                     /locus_tag="VCR92_001492"
     CDS             9..2171
                     /locus_tag="VCR92_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEP4268547.1"
                     /translation="MKVLLLAIMSIFLTCNIASAETIAIVSDTAYAPFEFKDSDQIYK
                     GIDVDIINEVAKRQSWDFSMSFPGFDAAVNAVQSGQASALMAGTTITNARKKVFHFSE
                     PYYDTKIVIATRKANAIKKYSDLKGKTVGVKNGTAAQAFLNNYKKKYDYTVKTFDTGD
                     LMYNSLSAGSIAAVMDDEAVIQYAISQNQDIAINMKGEPIGSFGFAVKKGSGYDYLVN
                     DFNTALKAMKADGTYQAIMTKWLGTDDKATTSQATGNPSAKATPIKDSYKIVSDSSFA
                     PFEFQNGKGKYVGIDIELIKAIAKQQGFKIEIANPGFDAALNAVQSSQADGVIAGATI
                     TDARKAIFDFSDPYYTSNIILAVKAGKNIKNYEDLDRKTVGAKNGTSSYSWLKENAPK
                     YGYNVKAFDDGSSMYDSLNSGSVDAIMDDEAVLKYAISQGRRFETPLEGISTGEVGFA
                     VKKGTNPELIEMFNNGLAALKKSGQYDDIIDKYLDSKKAATPSEKGADESTISGLLSN
                     NYKQLLAGLGTTLSLTLISFAIAIIIGIIFGMMAVSPTKSLRLISTVFVDIVRGIPLM
                     IVAAFIFWGVPNLIESMTGHQSPINDFLAATIALSLNGGAYIAEIVRGGIEAVPAGQM
                     EASRSLGLSYGTTMRKVILPQAVKLMLPNFINQFVISLKDTTIVSAIGLVELFQTGKI
                     IIARNYQSFRMYAILAIIYLIMITLLTRLAKRLEKRLN"
     gene            2171..2911
                     /locus_tag="VCR92_001493"
     CDS             2171..2911
                     /locus_tag="VCR92_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEP4268548.1"
                     /translation="MTELKIDVQDLHKSYGQNEVLKGIDAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLETITSGKVVVDGFELSDPKTNIDKARENIGMVFQHFNLFPHMTVLENI
                     IFAPVELGKESKEAAKKHGMALLEKVGLSDKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(3059..3211)
                     /locus_tag="VCR92_001494"
     CDS             complement(3059..3211)
                     /locus_tag="VCR92_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268549.1"
                     /translation="MTEKNGATFLMAVGFFLIAISPMVGNKYLHIVTGLALTGLGYYL
                     TKHKRP"
     gene            complement(3208..4587)
                     /locus_tag="VCR92_001495"
     CDS             complement(3208..4587)
                     /locus_tag="VCR92_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEP4268550.1"
                     /translation="MSHFSDKFMEISGKIGSQRHLVAIRDSFISMMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAKAMQPVIDINGYVYFGTIGIMALFFAFAFGYNLAVMHKINP
                     LAGGLISFGSFIATLPQTLTISTPLENASANLISNLKEMGLSVVTAGGASSIETSQWG
                     AIALKYVGATGLFTALIIGFLSSFVYAALTKRNITITLPDNVPPAVNKAFAAIIPGTV
                     AIYASAIFAYLIFALTGSSLSDVISTYIQLPLLGLSQGIGSVILLTFLVQLLWFFGLH
                     GHNVLAPVMDGIYMVALTENTAAYNTAHSAANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGIFNINEPITFGMPIVLNPTFVIPWLIVPPICASIA
                     YFATAIGLIPPVFLSVPWITPVGLYAYLATGGNIMAGLVSLFNLFVAFLIWAPFVILA
                     NKEKASDLA"
     gene            complement(4765..5214)
                     /locus_tag="VCR92_001496"
     CDS             complement(4765..5214)
                     /locus_tag="VCR92_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEP4268551.1"
                     /translation="MIISAEGDVSVHHCFEAMLISLQEDYRQNTLRQLSRDDIKAGIN
                     YVKHYGKYKERTVRVLITALEAPQLYTACFSSNHGIKELAYRLEALGENRTRITYSYD
                     YHPLDIFQKANYFIVGKLFKKSLERQSQAQLAALIQYAKQLQQPSSL"
     gene            complement(5211..5546)
                     /locus_tag="VCR92_001497"
     CDS             complement(5211..5546)
                     /locus_tag="VCR92_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEP4268552.1"
                     /translation="MTEPSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEEAQHLLQ
                     EATNSLNIAHKSQTHLLSQEAAGDAVELSLLMVHGQDHMMTALAFIDLAKELVTVYDK
                     MSAIQRGES"
     gene            complement(5549..5860)
                     /locus_tag="VCR92_001498"
     CDS             complement(5549..5860)
                     /locus_tag="VCR92_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEP4268553.1"
                     /translation="MKSIMLVCNAGMSTSMLVTKMQKAAQARDLEVSIWAVPVSEADN
                     EVAANSIDVLLLGPQVKFLLKDFKDKFEPDIKVDAINMADYGLMNGEKVLETALAMME
                     E"
     gene            complement(5883..7877)
                     /locus_tag="VCR92_001499"
     CDS             complement(5883..7877)
                     /locus_tag="VCR92_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEP4268554.1"
                     /translation="MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKEL
                     ISSLPEHGAHIISKQGRGYCLEIDHSMAFDIFWQESVTSKKRLADVTQVEESVDREDY
                     VLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEITHQHIQIRGK
                     EEDIRHFIMDYFFVTSFDNTLSTMVGNTFLEGINFAEIMIIVLDECRDAKLKLSDFVM
                     NNLVLHIALMVQRIRSGCPLELFSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVGKHWQDDNTDEKLQDHLKACIAKISQLTGMTLETDTNLFQGLLAH
                     MMPLTTRLENHIQLTNPLTEEIKSQYPEIFTLTKQTFSDLLVCQKNDVSDDEWAYISL
                     HLMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEER
                     LKTVDLIISSISLANLMFLTPVITVSVFLSNQDIETIRQFIGEQEGIKKEVSLPSQMS
                     LAKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGTETFVEDFYHQMVLREN
                     YSPVIYGEVLAFPHPANPMTYSEQVVVAICREPLEWDKAHQAVHFVFLLSPSKGHNHR
                     LKYVSPGLASFVNQVELQQALLEEPNYSKFMTVFTPLIHD"
     gene            complement(7983..9077)
                     /locus_tag="VCR92_001500"
     CDS             complement(7983..9077)
                     /locus_tag="VCR92_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEP4268555.1"
                     /translation="MVDLGFSLYPERYDVTKSKAYIDLCHSYGAKRLFMSLLQLAPAD
                     HQMFHCYAELIAYANQLGIRVIADVSPSFISQAGWSDQLIERAHAFGLAGLRLDEALP
                     LAEIVTLTRNPFGLKIELNMSTDKQLLMSLLATDAEQSNIIGCHNFYPHEFTGLSWQH
                     FKDMSRFYHEHDIETAAFITAQSASEGPWLLAEGLPTVEDHRHLPIGLQVELMKAIGT
                     IDNILISNQFISEEELAACTQALARPVTTIKVRPIIDLTEVEEKIIGYPHCYRGDVSD
                     YVIRSTMPRLVYAQESIAPRDQSKEVKRGSIIIDNDRYHRYKGELQIALKNFTVSSKA
                     NVVAEVREDYLSLLDDLRPWQEFCLEIDPS"
     gene            complement(9086..10486)
                     /locus_tag="VCR92_001501"
     CDS             complement(9086..10486)
                     /locus_tag="VCR92_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEP4268556.1"
                     /translation="MKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWDYWFS
                     IESAKFHHQIGPEKTSTFYENYKGDIALLKETGHTIFRTSIQWSRLIPEGVGEVNPKA
                     VTFYREVFQDIIAQGIKLIVNLYHFDLPYALQEKGGWENKATVWAYETYAKTCFELFG
                     DLVNTWITFNEPIVPVECGYLGYYHYPCKVDAKAAVQVAYNTQLASSLAVKACHKLHP
                     DHKISIVLNMTPAYPRSDAPEDVKAARIAELFQTKSFLDPSVLGVYPAELVSILEEAD
                     LLPQYSADELEVIKNNTVDFLGVNYYQPLRVQAPSKSQQEGDPLILDIYFEPYDMPGK
                     KVNPHRGWEIYEPGLYDIALNLKEHYGNIEWLVTENGMGVEGEEAFLADGQIQDDYRI
                     TFIEDHLIQLHKALGEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLESQKRTIKK
                     SGYWFKALSESNGFDK"
     gene            10711..11406
                     /locus_tag="VCR92_001502"
     CDS             10711..11406
                     /locus_tag="VCR92_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEP4268557.1"
                     /translation="MAYLNYFTKTEWALWLSSVLAILISALLFGKQAPLALIASLIGV
                     TSLIFSAKANPIGQGLVIIFSIIYAYLSLRNSYYGELMTYLFMTLPMTIFSLFTWLNH
                     PFEGKKSQVTISRLTPTDRRCLFVFTILVTLIFYGILASIQTAYLLVSTLSIATSFSA
                     VYLSYKRSPYFALAYGLNDLVLILLWMHAAQTDASQYAVVICFATFLINDSYTFYSWL
                     MLQRYQEKKVKKG"
     gene            complement(11411..11569)
                     /locus_tag="VCR92_001503"
     CDS             complement(11411..11569)
                     /locus_tag="VCR92_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268558.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     EKLKKDEA"
     gene            complement(11638..12951)
                     /gene="obgE"
                     /locus_tag="VCR92_001504"
     CDS             complement(11638..12951)
                     /gene="obgE"
                     /locus_tag="VCR92_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEP4268559.1"
                     /translation="MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFRVNEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDAET
                     GKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYVSINNELETYNLRLME
                     RPQIIVANKMDMPEAQENLKAFKKKLAAQYDEFDDLPMIFPISSLAHQGLENLLEATA
                     ELLAKTDEFLLYDESDLVDEEAYYGFAEAEKEFEITRDDDATWVLSGEKLERLFVMTN
                     MERDESIMKFARQLRGMGVDEALRERGAKDGDLVRIGKFEFEFVD"
     gene            complement(13008..13136)
                     /locus_tag="VCR92_001505"
     CDS             complement(13008..13136)
                     /locus_tag="VCR92_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEP4268560.1"
                     /translation="MAFGENGPRKKTTFEKVTMVVVILMVLVTVGGLIASALSVLM"
BASE COUNT         4040 a         2855 c         2425 g         4000 t
ORIGIN      
        1 cgcacaaaat aaaagtattg ctgcttgcga taatgtctat ttttttgaca tgcaatattg
       61 caagtgctga aactattgct attgtttcag atacagctta tgccccattt gaatttaaag
      121 actcagatca aatttacaaa ggaattgacg ttgatattat taatgaagta gccaaacgtc
      181 aatcttggga tttcagtatg agtttcccgg gttttgatgc agctgtaaat gctgtacaat
      241 ctggtcaagc gagtgctcta atggccggta caaccattac gaatgctcgt aagaaagtct
      301 ttcatttctc agagccatat tacgatacca aaattgtcat tgcgacacgt aaagccaatg
      361 ccatcaaaaa atacagtgac ttaaaaggaa aaacggtcgg tgttaaaaat ggaacagcgg
      421 ctcaagcctt tttgaataac tataaaaaaa agtatgatta tactgttaaa acatttgaca
      481 caggtgatct tatgtataat agtttatctg ctggttctat tgccgctgtt atggatgatg
      541 aagcggttat ccaatacgca atcagccaaa accaagatat tgctattaac atgaaaggag
      601 agcccattgg aagctttggg tttgctgtca aaaagggaag cggatatgat tatctagtta
      661 atgatttcaa tacagctctt aaagctatga aagctgatgg tacctaccaa gctatcatga
      721 ccaagtggtt aggcacagat gataaagcta ccaccagtca ggcaacggga aatccatctg
      781 ccaaagctac acctataaag gacagttata aaattgtctc tgattcgtct tttgcacctt
      841 ttgaatttca aaatggtaag ggcaaatacg ttggtattga catagaatta atcaaagcta
      901 ttgctaaaca acaaggtttc aaaattgaaa tcgctaatcc aggtttcgat gctgccttaa
      961 atgctgtgca atctagccaa gcagatgggg tcattgctgg tgcaactatt actgacgctc
     1021 gtaaagctat ctttgatttt tctgatcctt attatacttc taatatcatt ttagctgtta
     1081 aagctggaaa aaacatcaag aactatgaag acttagacag aaaaacagtc ggtgctaaaa
     1141 acggcacttc atcttactct tggttaaaag aaaacgctcc taaatatggt tataatgtca
     1201 aggcatttga tgatggttct agcatgtatg atagcttaaa ttcaggttct gtagatgcta
     1261 tcatggatga tgaggcggtt cttaaatacg ctatttctca aggtcgtcgc tttgaaacac
     1321 ctcttgaggg catttctact ggtgaagttg gttttgctgt caagaaagga actaatccag
     1381 aattaatcga aatgttcaac aatggcttag ctgctctcaa aaaatctggt cagtatgatg
     1441 acattataga taaatacctt gactctaaga aagctgcaac tccttctgaa aaaggtgctg
     1501 atgagtctac tatttcaggc ctattatcaa ataactacaa acaactattg gcaggacttg
     1561 gaaccacgct cagtttaacc cttatttcat ttgctattgc tataattatc gggatcatct
     1621 ttgggatgat ggccgtgtca ccaactaaat cacttcgact catttcaacg gtctttgtag
     1681 acattgttcg agggattcct ttgatgattg tggctgcctt cattttctgg ggagtaccaa
     1741 accttatcga gagtatgacc ggccaccagt caccgattaa tgatttctta gctgctacaa
     1801 ttgcactgtc acttaatggc ggagcctata ttgctgaaat tgttcgcggt ggtatcgaag
     1861 ctgttccagc agggcaaatg gaagctagtc gaagtcttgg tttgtcttac ggaaccacga
     1921 tgagaaaagt aattctccca caagctgtga aactaatgtt acctaacttt atcaatcagt
     1981 ttgttatttc attgaaggat acaacaatcg tctcagcaat tggtttagtg gaactcttcc
     2041 aaacaggtaa aatcattatt gctagaaatt accagtcgtt ccgtatgtat gctattttag
     2101 caattattta ccttatcatg attacactct taacaagact tgcaaaacgt ttagaaaaga
     2161 ggcttaacta atgacagaat taaaaattga tgttcaagat ttacacaaat cttatggtca
     2221 aaatgaagtc ttaaaaggaa ttgatgccaa attctacgaa ggtgatgtcg tttgtatcat
     2281 tggtccttct ggttctggga aatcaacctt tctacgtacc ctcaaccttc tagagacgat
     2341 taccagtggt aaggtcgtgg tggacggttt tgaattatca gatcctaaga ctaatattga
     2401 caaggcacgt gaaaatatcg ggatggtatt ccaacacttc aaccttttcc ctcacatgac
     2461 tgttcttgag aatattatct ttgctcctgt tgaattaggt aaagagtcta aagaagctgc
     2521 taaaaagcac ggcatggcac ttctagaaaa agtcggactt tctgataagg ccgacgcctt
     2581 cccaggaagt ttatccggcg ggcaaaaaca gcgtgtcgcc atcgccagaa gtttagcaat
     2641 gaacccagat attatgctct ttgatgaacc aacttctgct cttgaccccg aaatggttgg
     2701 ggacgttttg aacgttatga aagacttggc agaacaaggc atgaccatgt tgattgttac
     2761 tcacgaaatg gggtttgctc gtcaagtagc taaccgcgtt atctttacag atggtggtca
     2821 atttttggaa gatggaactc ctgaagaaat ttttgaccat cctaagcacc ctcgtctcat
     2881 tgaattttta gacaaggtct taaacgtcta atagagcaga caccatacta acttccaaaa
     2941 aataataagg caaggaaaca ggtttccttg ccttttttgg ttactgttat tattcaaacc
     3001 agcaaaatag ggatactctt atgactctct acttcataag agtgtcccct atgctttttt
     3061 atgggcgttt atgtttagtg aggtaataac ctaatcccgt aagagctagt cccgtcacta
     3121 tgtgtaagta tttgttacca accatcggac taatggcaat gagaaaaaag ccaacagcca
     3181 ttaaaaaagt tgctccattt ttttctgtca tgcaaggtca ctcgcttttt ctttattggc
     3241 caaaatgaca aatggtgccc agataaggaa ggcaacaaag aggttaaaca gtgaaaccaa
     3301 acctgccata atattacctc cagtagctag gtaagcataa agtccaacag gggtaatcca
     3361 aggtactgat aagaataccg gtggaatcaa acctattgca gtagcaaaat aagctatgct
     3421 agcacaaatt ggtggcacaa ttagccatgg aatcacaaag gttggattca aaacaattgg
     3481 catcccaaat gtaattggtt cgttgatatt gaaaataccc attggtgcgg acaatttggc
     3541 aatggtttta tgctcttctc gttttgagaa tatgaagata gcaataatca atgccaaggt
     3601 tactcctgaa ccacccattt gagcataagc atcaaaggac ccgcgtgtcc aaaggtatgg
     3661 taaattagca gcgctatgcg ctgtattgta agcagctgta ttttctgtta aagctaccat
     3721 ataaatacca tccatcactg gggctaagac attatgacca tgcaagccga agaaccagag
     3781 cagttgaact aagaaggtta acaagataac tgaaccaata ccctgtgata agcctagcaa
     3841 tggtaattgg atataggttg aaatgacatc acttagggaa gaacctgtta atgcgaagat
     3901 gaggtaggcg aaaattgccg aagcgtaaat cgcaactgtt cctggaataa tggcagcaaa
     3961 ggctttatta accgcaggtg gtacattatc tggtaaggta atggtaatat tacgtttggt
     4021 caaagccgca tacacaaaac ttgataaaaa gccaataatt aaagctgtga acaagcctgt
     4081 ggcaccgaca tactttagag ctattgctcc ccattgacta gtttcaatac ttgaagctcc
     4141 acccgcagta acgactgaaa gccccatttc tttcaaattg ctaattaggt tagcagaggc
     4201 attttcaagt ggtgtcgaaa tggttaaagt ctgaggtagg gtggcaataa atgagccaaa
     4261 agaaatcaat cctcccgcca atggattaat cttatgcata acagctaaat tgtaaccgaa
     4321 agcaaaggca aaaaagagcg ccatgatacc aattgtccca aaataaacat agccattgat
     4381 gtcgataaca ggttgcatag cttttgcaaa ccctgtccat cccatattgt ttggaatatc
     4441 gcgtaaaaaa acgttcaata agacagcaac tgaacctgcc atggtaatag gcatcattga
     4501 aataaaggaa tcacgaatag ctactaaatg ccgttgtgac ccaatttttc ctgaaatctc
     4561 cataaactta tcagaaaaat gcgacataaa tcttctcctc tttttatttt tttaatgtaa
     4621 caaaggtaac cttaaaagca gcggtgtctg cctaacacaa ttatctcaaa atcatccttg
     4681 ttaaacgtga tgcttagaga taaccggtaa tcggctctta tccaaatgaa cccttctctc
     4741 tcattcaagg tctatgaata atcttcacaa agacgatggt tgctgcaact gtttagcata
     4801 ttggataagg gctgctaact gggcttgaga ttggcgttct aggctttttt tgaacagttt
     4861 gccaacaata aaataatttg ctttttgaaa aatatctaga ggatgatagt cataagaata
     4921 ggtaattcta gtccgattct cccccagagc ctctaatcga taagccaatt cctttatccc
     4981 atgattggaa ctaaaacaag cagtatataa ttgcggagct tctagggccg taataagcac
     5041 cctcactgta cgctctttgt atttaccata atgtttaaca tagtttatcc ccgctttgat
     5101 atcatctctt gacaactgtc tcaaggtatt ttgtcgataa tcttcttgga gcgatatcag
     5161 catggcttca aaacaatgat ggacggaaac atctccttct gctgaaatga tcatgactca
     5221 cctctttgta ttgctgacat tttgtcgtaa acggtaacca attccttggc taaatcaata
     5281 aaggctaagg cagtcatcat gtgatcttgc ccatgcacca tcaataaaga caattcaacc
     5341 gcatcaccag ctgcttcttg ggacagcaaa tgtgtctgcg atttatgggc aatatttaac
     5401 gagtttgtcg cttcttgaag taagtgctga gcctcctcaa actgcccatc tcgtgctgca
     5461 tgaatagcct ctacggcctt gcccttggct tcgcctccat acatgattaa gcccataata
     5521 gcttctaagt tggatggttc cgtcatgcct actcctccat catcgctagg gctgtttcaa
     5581 ggactttttc accgttcata agaccataat cagccatgtt aatggcatct actttaatat
     5641 ctggttcaaa cttatcttta aaatccttta gtaagaattt gacttgtgga cctaacaaga
     5701 gaacgtcaat gctattagca gccacttcgt tgtcagcttc actcacagga actgcccaaa
     5761 tagaaacttc aaggtcacgc gcttgggctg ctttttgcat cttagtcacc aacatactag
     5821 ttgacatacc ggcattacaa actaacataa tagatttcat aaggtttctc cttttaatcg
     5881 ttttaatcat gaataagtgg ggtaaacact gtcatgaatt tggaataatt tggttcttct
     5941 agtaacgctt gctgaagctc cacctgattg acaaaagatg ccaaacctgg tgatacatat
     6001 tttaacctat gattatgccc tttagacggg gataatagaa agacaaaatg aacagcttga
     6061 tgcgccttgt cccactcaag aggctctcgg caaatagcca ctactacctg ttcagaataa
     6121 gtcatgggat tagcaggatg cggaaaggca agcacttctc catagatgac tgggctgtaa
     6181 ttttccctca gtaccatttg atgataaaag tcctctacaa acgtttctgt tcccgcctcg
     6241 tcaagacaag caatcatccg taaaagcaag tcttcctttg agattttctc gtctaaataa
     6301 agaaaacgat tagggctaaa aacacctgtt agaagctgct ctgcttttgc taaactcatc
     6361 tgtgacggta aactgacctc tttcttgata ccttcttgtt ctccaataaa ttgtcgaata
     6421 gtttcaatat cctgatttga caaaaaaaca ctgacagtaa tcactggtgt taaaaacatc
     6481 agattggcaa ggctgataga ggaaataatc aaatcaacgg ttttcagtcg ctcttcggtt
     6541 atttcatagt aactgataac atcgacaata cgcaaacgtc cttcaaattc cttttccaag
     6601 cgatttttca acatcatggc actaccataa cctgtggcac aaactactag aaccctcaat
     6661 ttatgacggt ttgaataacg ctcaatggcc gccattaaat gcaaactaat ataagcccat
     6721 tcatcatctg agacatcatt cttttgacat acaagcaaat ccgaaaaggt ctgcttggta
     6781 agggtaaata tttcaggata ctggctttta atttcctcag ttaaaggatt agtcagctga
     6841 atatggtttt caagacgtgt ggtcaagggc atcatgtggg ctaataaacc ttgaaataaa
     6901 ttggtatctg tttctaaagt catgcctgtc aattgactaa tcttggcaat acatgctttt
     6961 aaatggtcct gcaacttttc atcggtatta tcatcttgcc aatgcttacc aacagaatgt
     7021 ttgaccttta gatgcagtgc aatataatta gcctcctctt taggaaaacg tatccccatc
     7081 acttcttcca ctcgatacaa aatgcgcaga gctacttgat actcatcaga ctgacgaata
     7141 gctattggaa tggaaaacag ttctaatgga caccccgatc gaatacgctg aaccattagg
     7201 gcaatatgca agactagatt attcatgaca aaatcagaaa gtttcaactt agcatcccga
     7261 cattcatcca agacaataat catgatttct gcaaaattaa taccttcaag aaaggtatta
     7321 cctaccatgg tggacaaggt gttatcaaaa ctagtaacaa aaaaataatc catgataaaa
     7381 tgcctaatgt cctcttcttt acctcttatt tgaatatgtt ggtgagttat ttcaagctct
     7441 aactggtaag gtattatgcg ctccttaatg cctgctaaaa catgttttaa agttgtccga
     7501 ctgatataca attcttgaca aagctcttca aaatcctgaa cggcatcttc aaaaaagaat
     7561 ttatgaagca cataatcttc tcgatcaacc gattcttcca cttgagtcac atctgctaaa
     7621 cgttttttag acgtcacact ttcttgccaa aagatgtcaa atgccataga gtggtcaatt
     7681 tctaagcagt aacctcgacc ttgtttagaa atgatgtgag ctccgtgttc aggaaggcta
     7741 ctgatcagtt ctttgaggta tttcctaacc gtacggtcac tcataccaat aacctcagcc
     7801 agagttgcac tagagacaaa ctgctctttg tgatggatta gaaatgttat gatggccagt
     7861 tctttttttg ataacattag tcctccttac tactttagaa aacgctctct accctctttt
     7921 agtgtaccaa atatttcctg aaaaaggtga ccatcatttt ccgcattgat tgtgaaaaga
     7981 atctatgatg ggtcaatctc caaacaaaat tcctgccaag gtcgcaaatc atctaacaaa
     8041 ctaagatagt cctctctgac ctcagcaacc acattagctt ttgaactaac cgtaaaattt
     8101 ttcaaagcaa tttgcagttc tcccttatat cgatgatagc ggtcattgtc aataataatg
     8161 ctacctcgtt tgacctcctt agattggtct cttggagcaa tcgattcctg agcataaact
     8221 agacgtggca tggttgatcg aatcacataa tcagatacat cgccacgata acaatgcgga
     8281 tagccaatga ttttctcctc aacttctgtc aaatcgatga taggcctaac cttgatcgtt
     8341 gtgactggtc ttgctaaagc ctgagtacat gctgccaatt cttcttccga aatgaattgg
     8401 ttagatatga ggatattatc aatggttcct atcgctttca ttaattctac ttgcaggcca
     8461 atgggcaagt gcctatggtc ttccactgtc ggcaagcctt ctgccagtag ccaagggcct
     8521 tcagatgctg actgagcggt aataaaagca gccgtttcaa tatcatgctc atgataaaaa
     8581 cgtgacatat ccttaaaatg ttgccatgac aaaccggtaa attcatgtgg ataaaaatta
     8641 tggcaaccaa taatattgct ctgttctgca tctgtcgcta gcaatgacat caataattgt
     8701 ttatcagtgc tcatattaag ttcaatttta agcccaaagg gatttcttgt taaagttaca
     8761 atctctgcta gagggagagc ctcgtctaag cgtaagcccg ctaacccgaa ggcatgagct
     8821 cgttcaataa gctgatctga ccaaccagct tggctaataa agcttggact aacgtcagca
     8881 attactcgaa tgcctaattg atttgcataa gcaatgagct ctgcgtagca atgaaacatc
     8941 tggtgatcag ctggtgccag ctgtaagaga ctcataaaca agcgcttggc tccatagcta
     9001 tgacataagt caatataagc tttactcttg gtaacatcat accgctcagg gtatagagaa
     9061 aatcctaaat caaccatatt gcctcctatt tatcaaaacc atttgactcg ctcaacgcct
     9121 taaaccagta acctgatttt tttatggttc gcttttgact ctctaaatcc aaagctacca
     9181 aaccatatcg gtttttataa gcatttaacc aagaccagca atcaataaaa gtccacaaga
     9241 ggtagccttt gcagttggct ccttctccca aagccttatg aagctggata agatgatcct
     9301 cgataaaggt gatgcggtag tcatcttgta tctggccatc tgctaaaaaa gcttcttcac
     9361 cttcgacacc cataccattt tccgtgacta gccattcgat gttaccatag tgttctttta
     9421 aattaagggc aatatcataa agtcctggtt cataaatttc ccaaccccgg tgaggattga
     9481 cttttttacc aggcatatca taaggttcaa aataaatatc taagataagg gggtccccct
     9541 cttgctgtga cttactaggt gcctgaaccc gcaaaggctg ataataatta actcccaaaa
     9601 aatcaacagt attgtttttg ataacctcta attcatcagc actatattga ggtaataaat
     9661 cagcttcctc taaaatggaa actaactctg ctgggtaaac acccaaaact gatggatcta
     9721 ggaaggattt ggtttggaaa agctctgcga ttctagcagc cttgacatct tcaggagcat
     9781 cactccgagg ataagcaggt gtcatgttaa gcacaatact aatcttgtgg tcgggatgaa
     9841 gcttatgaca agctttaacc gccagtgaac tggccagttg tgtgttgtaa gccacttgaa
     9901 ctgctgcctt ggcatctact ttacaagggt agtgataata acctaaatag ccacattcga
     9961 ctggaacaat cggttcatta aaggtaatcc aagtgtttac taaatcacca aaaagctcaa
    10021 aacaggtttt tgcgtaggtt tcataagccc agacagtagc tttgttttcc cagccacctt
    10081 tttcttgcaa ggcatagggg aggtcaaaat gatagaggtt aacaatcaat ttaatacctt
    10141 gagcaataat gtcttgaaat acttctcggt aaaatgtcac cgcctttgga ttaacctccc
    10201 cgactccttc tggaatcaat cgagaccact ggattgaggt ccgaaaaatc gtgtggcctg
    10261 tttctttcaa aagggcaatg tcacccttat agttttcata aaaggttgag gttttttctg
    10321 gaccaatttg gtgatgaaac ttagctgact caatactaaa ccagtaatcc cagttgctag
    10381 gtcctttgcc atctccagga accgttcctt cgctttgagg cccagatgtg gaacttcccc
    10441 ataaaaagcc atctggaaat tgataacggt gttttctttg tttcatatcc tttgtccttt
    10501 ctttgctcac ttctcttttt attataagaa gaaaaacagg tgatgtaaac gctttaaaaa
    10561 atctgttttt tccttatcat cacggaaaat aagtgattta aagcttgaca tattttatta
    10621 tcttaaagag cctatctaac ctgccctgct acttcttatc aaaaccaagc ccctattgac
    10681 agatgcctta gcctatgttt gaataggggt atggcttatt taaactactt tacaaaaacc
    10741 gagtgggcac tttggttaag ctctgtcttg gccattttaa ttagcgccct tttattcggt
    10801 aagcaagctc ccttagcttt aatagcttct ttgattggtg tgacctctct catttttagt
    10861 gctaaagcta atcctattgg tcaagggctc gtcattattt tttccattat ctatgcctat
    10921 ctttcattac gaaacagtta ctatggagag ttaatgacct atcttttcat gaccctccct
    10981 atgactattt tttcactttt tacttggtta aaccatcctt ttgaagggaa aaaatcacaa
    11041 gtgactattt cacgattaac acccactgat cgaagatgtc ttttcgtttt tactatactg
    11101 gtcactctta ttttctacgg catcttggct tctattcaaa cagcctattt acttgtctcc
    11161 actttatcga ttgccacttc tttctcagcc gtttatctca gctataagcg aagcccttat
    11221 tttgctttgg cttatggact caatgatcta gtcctcattc tcttatggat gcatgctgct
    11281 caaacagatg ccagccaata tgctgtggtc atctgctttg ccacctttct tattaatgat
    11341 agttacactt tttatagttg gctaatgctc caacgttacc aagaaaaaaa ggtcaaaaaa
    11401 ggatgagggc ctaagcctca tcctttttca atttttcacg ttctaagcgc aaacgtctat
    11461 tgggatttaa aagattaaac aattcttcta atttctcagc attccaaaca tctgctgccg
    11521 atacaaaatt tccatcctta tccttaaagg atatcggttt atcacccata atcagaaacc
    11581 tccatcttaa agataaaaca caaggctgct atggcaatgc catttctaaa gaccacatta
    11641 atccacaaat tcaaattcaa atttgccaat acgaacaaga tccccgtctt ttgctccacg
    11701 ttcacgaagg gcttcgtcaa cccccatacc gcgcaattga cgggcaaatt tcatgatgga
    11761 ttcgtcacgt tccatattgg tcatgacaaa gagacgttct aacttctcac cagacaagac
    11821 ccaagtagcg tcatcgtcac gtgtgatctc aaattctttc tcagcctcag caaaaccata
    11881 gtaagcttcc tcgtccacca gatcagattc atcatacaat aagaattcat ccgtcttagc
    11941 aagtaattct gccgttgctt ctaacaagtt ctctaagcct tgatgtgcta ggcttgaaat
    12001 agggaaaatc attggcaaat catcaaactc gtcatattgg gcagccaatt ttttcttgaa
    12061 ggctttcaag ttttcttgag cctctggcat gtccatttta ttagccacaa taatctgtgg
    12121 gcgctccatc aatcgcaaat tataggtttc cagctcgtta ttaatagaaa cataatcttc
    12181 gtaaggatca cgaccctcac tagcagacat gtcaatcaca tgaagaataa cccgtgtccg
    12241 ctcgatatga cggaggaatt gagttcccaa accaacccct tggctagcac cttcaatcaa
    12301 acctggcaga tctgccatag caaagctatc acctgacttt gtacgaacca ttccaagatt
    12361 aggaacaata gtggtaaaat gataggcacc aattttcggt ttagctgatg acacaacact
    12421 taacaaggtt gatttcccaa cagatgggaa tccgaccaag ccaacgtcag ctaagatttt
    12481 gagttctaac tctaactgac gttcctcacc tggctcacca ttttcagcaa tctctggcgc
    12541 aggattacga ggagttgcaa aacggatatt cccacggcca ccacgaccac ccttagcaat
    12601 gaccacttct tgaccatgtt ctactaagtc tgtaattact tttccagttt cagcatcacg
    12661 aaccgttgtc ccttgaggaa caaaaacaat caaatcttct gcaccacggc cgtgcatgcc
    12721 tttggtcata cctttttcac cagatttcgc cttgaattta cgattatagc ggaaatccat
    12781 caaggtacgc aaaccttcgt tcactcggaa gataactgag ccacctttac cgccgtctcc
    12841 tccccaagga ccgccatttg ggacgtactt ttcacgacga aaagctacca taccatcgcc
    12901 accacggcct gcttggacac tgatttttgc cgtatctaaa aacatactca tacttttttt
    12961 attctctaac tttcttttac tttaaaaaaa cgcctttcag cgtttcctta cattaatact
    13021 gatagggcac tcgcaataag cccgccaaca gttacaagaa ccattaggat aacaacgacc
    13081 attgtcactt tttcaaaggt tgtttttttg cgaggtccat tttctccaaa tgccacgtta
    13141 aatacctcat ctattgattt ttcttcttat atcttaacat gaaagatcgt tttaggcaaa
    13201 taccagatga atatttacgc tatgtaggct attactgagt attgtatctt gtgaatttca
    13261 tatgaatatg atacattagc atttgcaaaa taatgttaca gataaaaacc tcctcgtctg
//
LOCUS       DATWEK010000039        13166 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.039, whole genome shotgun sequence.
ACCESSION   DATWEK010000039 DATWEK010000000
VERSION     DATWEK010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13166
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.039"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            517..1044
                     /locus_tag="VCR92_001506"
     CDS             517..1044
                     /locus_tag="VCR92_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEP4268561.1"
                     /translation="MSIDDYRPTYMVEAIYDLRANDLLRHGITAVLVDLDNTLIAWNN
                     PDGTPEVRAWLDEMTIADISVVVVSNNKHSRVERAVSRFGVDFISRALKPFAYGIEKA
                     IARYGFDRNEVIMVGDQLMTDIRASHRAGIKSVLVKPLVASDAWNTKINRWRERRVMA
                     KLEEKYGKLSYQKGI"
     gene            1044..2162
                     /gene="yqeH"
                     /locus_tag="VCR92_001507"
     CDS             1044..2162
                     /gene="yqeH"
                     /locus_tag="VCR92_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEP4268562.1"
                     /translation="MEELFCIGCGIQIQTEDKEKAGFTPAAALKKGMETGELYCQRCF
                     RLRHYNEITDVHITDDEFLRLLHEVGDSDALVVNVIDIFDFNGSIIPGLSRFISGNDV
                     LLVGNKKDILPKSVKDGKVTQWLTERAHEEGLRPLDVMLTSAQNKYAIKDLIERINEL
                     RNGRDVYVVGVTNVGKSTLINAIIQEITGDKDVITTSRFPGTTLDKIEIPLDDGSFIF
                     DTPGIIHRHQMAHYLSPKELKIVSPKKEIKPKTYQLNPEQTLFLGGLSRFDFINGERQ
                     GFTAFFDNQLELHRTKLAGADAFYDKHVGTLLTPPGKKELTAFPKLVRHEFTIDQKMD
                     IVFSGLGWIRVNGQKDSKAIVAAWAPEGVAVIVRKAII"
     gene            2188..2496
                     /gene="yhbY"
                     /locus_tag="VCR92_001508"
     CDS             2188..2496
                     /gene="yhbY"
                     /locus_tag="VCR92_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEP4268563.1"
                     /translation="MLTSKQRAFLKSEAHSLKPIVQIGKNGLNDHIKTSIRQALDARE
                     LIKVTLLQNTDEDIHEVAEILEEEIGCDTVLKIGRILILYKVSAKKENRKLSPKVKAI
                     "
     gene            2565..3197
                     /locus_tag="VCR92_001509"
     CDS             2565..3197
                     /locus_tag="VCR92_001509"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEP4268564.1"
                     /translation="MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVA
                     DQVRQQLGLDQVLLMPECKPPHVDAKETIDEKHRLRMLELAIEDVEGLAIETCELERQ
                     GISYTYDTMLYLTEQHPDVDFYFIIGADMVDYLPKWHRIDELVKLVQFVGVQRPKYKA
                     GTSYPVIWVDLPLMDISSSMIRDFIKKGRQPNYLLPKRVLDYITQEGLYQ"
     gene            3194..3787
                     /gene="yqeK"
                     /locus_tag="VCR92_001510"
     CDS             3194..3787
                     /gene="yqeK"
                     /locus_tag="VCR92_001510"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEP4268565.1"
                     /translation="MTYEDYLPYSRTELLAKIAEQMSPKRFKHVLGVEKAALSLAECY
                     GCNPDKAGLAALLHDYAKECPDQVFLDLIDKYQLSPELAKWNNNVWHGMVGIYKIQED
                     LGLKDKDILRAIEIHTVGAAEMTLLDKVLYVADYIEEGRIFPLVDDARKIAKLDLNQA
                     VAYETVNTVAYLASKAQPIFPQTLDTYNAFCSYLKEY"
     gene            3811..4164
                     /gene="rsfS"
                     /locus_tag="VCR92_001511"
     CDS             3811..4164
                     /gene="rsfS"
                     /locus_tag="VCR92_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEP4268566.1"
                     /translation="MKKEELLKIVVEATDEKRAKDILALDLEGLTSLTDYFVIASATN
                     SRQLEAIADNIREKVKEAGGDASHVEGNSQAGWVLLDLTDVVVHLFLEDERYHYNLEK
                     LWYEAPAVALDAYLA"
     gene            4212..4955
                     /locus_tag="VCR92_001512"
     CDS             4212..4955
                     /locus_tag="VCR92_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEP4268567.1"
                     /translation="MKHNYEKFASVYDAVMDDSLYDLWTDFSLRHLPKSKGRNRLLEL
                     ACGTGIQSVRFAQAGFDVTGLDLSQDMLAIAKKRAQSAKKKIDFIQGNMLDLSQVGQF
                     DFVTCYSDSICYMQDEVDVGDVFKEVYDVLANDGIFIFDVHSTYQTDECFPGYSYHEN
                     ADDFAMVWDTYADEAPHSVVHELTFFIQEDDGRFSRFDEVHEERTYELLTYDILLEQA
                     GFKSFKVYADFEDKEPTKTSKRWFFVAYK"
     gene            5209..6315
                     /locus_tag="VCR92_001513"
     CDS             5209..6315
                     /locus_tag="VCR92_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEP4268568.1"
                     /translation="MTVTGIIAEFNPFHNGHKYLLETAEGLKIIAMSGNFMQRGEPAL
                     IDKWIRSEMALKNGADIVVELPFFVSVQSADYFAQGAIDILCQLGIQQLAFGTEDVID
                     YQKLIKVYEKKSKQMTAYLSTLEDTLSYPQKTQKMWEIFAGVKFSGQTPNHILGLSYA
                     KASAGKHIQLCPIKRQGAAYHSKDKNHLLASASAIRQHLNDWDFISHSVPNAGLLINN
                     PHMSWDHYFSFLKYQILNHSDLTSIFQVNDELASRIKKAIKVSQNIDHLVDTVATKRY
                     TKARVRRILTYILVNAKEPTLPKGIHILGFTSKGQAHLKKLKKSRPLITRIGAETWDE
                     MTQKADSIYQLGHQDIPEQSFGRIPIIIKNERLN"
     gene            6797..7513
                     /locus_tag="VCR92_001514"
     CDS             6797..7513
                     /locus_tag="VCR92_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP4268569.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRTAYGKNGGNMGASGSVSYLFDKKGVIVFAGDDADSVFEQLLEADVDVDD
                     VEAEEGTITVYTAPTDLHKGIQALRDNGVEEFQVTELEMIPQSEVVLEGDDLETFEKL
                     IDALESDDDVQKVYHNVADF"
     gene            7716..8558
                     /locus_tag="VCR92_001515"
     CDS             7716..8558
                     /locus_tag="VCR92_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEP4268570.1"
                     /translation="MIKKQYLGRATIALASTLVLAACGSSKTAESGNQGSSKEVLFAT
                     VGTTAPFSYEKGGQLTGYDIEVAKAVFKGSDDYRVSFKKTEWSSIFTGLDSGKYQMGG
                     NNISFTKERSAKYLFSYPIGSTPSVLVVPKDSDIKSFDDIQGHTTQVVQGTTSVAQLE
                     DFNKKHSDNPVTLKFTNENITQMLTNLSEGKADFKIFDAPTVNAIIKNQGLDNLKTIE
                     LTSTEQPFIYFIFSQDQEKLQSFVNKRIKELTADGTLSKLAKEHLGGDYVPSDKELKL
                     PTAN"
     gene            8885..9730
                     /locus_tag="VCR92_001516"
     CDS             8885..9730
                     /locus_tag="VCR92_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEP4268571.1"
                     /translation="MSFKKWIGIVGIALASTVLVACSEKQDDKNTLTIGVMTKTESDQ
                     ARWDKVEELLKKDNITLKYKEFTDYSQPNKAVANGEVDINAFQHYNFLNNWNKENKEH
                     LVAIADTYISPINLFSGTSQDGKAKYKSVADLPNGAQIAVPNDATNESRALYVLQSAG
                     LIKLNVSGDQLATIANISENKKKLDIKELDASQTARALVSADAAVVNNSYAVPAKIDY
                     KTSLFKEKADDNSKQWINIIAGQKDWEKSEKADAIKKLIKAYQTDEVKKVVEKTSNGI
                     DVSVW"
     gene            9980..11044
                     /locus_tag="VCR92_001517"
     CDS             9980..11044
                     /locus_tag="VCR92_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEP4268572.1"
                     /translation="MNEAIIQLDHIDITFRQKKRVIEAVKDVTVHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQAPTNGKITVDGDVTFDQGKIQLSADALRQKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSSLSKTEKEHKVIELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRKLGLTIVMITHEMQIVKDICN
                     RVAVMQNGVLIEEGSVLDIFSNPKEALTQEFITTATGIDEALEKINQQDIVKHLPANA
                     LLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVGDMIVVLEGQAENIL
                     AAEKALHEAGVDVSILKRGA"
     gene            11045..11737
                     /locus_tag="VCR92_001518"
     CDS             11045..11737
                     /locus_tag="VCR92_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4268573.1"
                     /translation="MSQLIQTYLPNVYELGWSGDAGWGLAIWNTLYMTIVPFIVGGAI
                     GLLLGLLLVLTGPDGVIENKTICWVIDKVTSIFRAIPFVILIAILASFTYLLLRTTLG
                     ATAALVPLTFATFPFYARQVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQF
                     IGDSLTRRFSHK"
     gene            complement(11791..13161)
                     /gene="brnQ"
                     /locus_tag="VCR92_001519"
     CDS             complement(11791..13161)
                     /gene="brnQ"
                     /locus_tag="VCR92_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEP4268574.1"
                     /translation="MKQKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGHQILWSIIG
                     FCLTGVSLPLLGVIAVAKSGSGDVESLARPISKWYAIFYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDNTTNKAIYAILFFGLSYFLAIKPSKLAENIGKFLTPTLLVVISIL
                     VIASFVHPAGNYGDAFNAGVGVNNAFKDFPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDKEVTKITLISGAIAILLLALVYIFVGRIGATSQSLFPFSDGSFTLHGNPV
                     NGGQILSHASRFYLGGIGQAFLAVVIFLACLTTSTGLITSSAEYFHKLVPALSHIAWA
                     TIFTLLSAFFYFGGLSVIINWSAPVLFLLYPLTVDLIFLVLAQKCFNNDPIVYRTTIG
                     LTFIPAIFDALLTLSQMTGLFHLPEAVVTFFQKTVPLGQFSMGWIIFAAIGFLIGLIL
                     SKTKKS"
BASE COUNT         4331 a         2072 c         2748 g         4015 t
ORIGIN      
        1 gtaatcattt tttgatttac agttattatc atgtgttatc tggcgactgt cctgtttaca
       61 agtaagttca caagtatggg ataaaatagt ataaactata gtaaatactg aatagtcata
      121 gaaaaatatc ggcataggtc agaaaagctg atatgtttaa tactttttgc ggatatctac
      181 tgtatttaaa tgtatttgat atccttgtca aggatatacg tctaaacaag ttcaaaacga
      241 aatcatttgt gattatctta tcaggagttg actcttgata agatttttgt atatcagtac
      301 tgtggtacgt ttagatagct tggcagtgaa tttatagagt gtcaaacaac gagtgttttg
      361 tgttacacta accattagaa gagtctattg ttgagcatat caaggtgtta tcttttcgag
      421 ttgaggtatc atatctagta tatttaacta tggttttaaa tgctatttca aaaaaaatat
      481 gataaaatag aaagtactaa ttattttgga gatgacatga gtatcgatga ttataggccg
      541 acctatatgg tagaggctat ttatgattta agagcaaatg atttgttgcg tcatggtatt
      601 acggctgttt tagtggattt agataatacc ttaattgcat ggaataatcc tgatggcaca
      661 ccagaggttc gcgcttggct tgatgaaatg actatcgcgg atattagcgt ggttgttgtt
      721 tcaaataata aacattctcg tgttgagcgt gccgtttcac gctttggtgt tgactttatt
      781 agccgggctt tgaagccatt tgcttatggt attgaaaaag ccattgctcg ttatggattt
      841 gatcgcaacg aggttatcat ggttggagat cagctaatga ctgatatcag agctagtcat
      901 agagctggaa taaaatcagt tttagtcaaa ccacttgttg cttctgatgc ttggaatact
      961 aaaattaacc gctggcgtga acgccgtgtg atggcaaaat tagaagagaa atatggtaaa
     1021 ttatcatatc aaaaaggaat ttaatggaag aattattttg tataggctgt ggtatccaga
     1081 ttcaaactga agacaaagaa aaagctggtt ttacgccagc tgctgctttg aaaaagggta
     1141 tggaaacagg agaactctat tgtcagcgct gctttagatt gaggcattat aatgaaatta
     1201 cagatgtcca tattaccgat gatgaatttt taagacttct tcacgaagtg ggtgatagtg
     1261 atgctcttgt ggttaatgtg attgatattt ttgactttaa tggttctatt attccaggtc
     1321 tatctcgctt tatttctggt aatgatgtct tactggttgg gaataaaaaa gatattttgc
     1381 caaagtctgt taaggatggt aaagttactc aatggttgac ggaacgtgca cacgaagaag
     1441 gtcttcgccc tttagacgtt atgttaacga gcgctcaaaa taaatatgcg attaaagact
     1501 tgattgagcg tatcaatgag ttacgtaatg gtcgagatgt ttatgttgtg ggggtcacta
     1561 atgttggtaa atcgacctta attaatgcca ttattcaaga aattacaggg gataaagatg
     1621 tgattacgac gtcccgcttc cctggaacga cccttgataa aattgaaatc ccactggatg
     1681 acggtagctt catatttgat acgccaggta ttattcatcg tcatcaaatg gctcattatt
     1741 tatcccctaa agagctaaaa atagtgagtc ctaagaagga aatcaagcct aagacgtatc
     1801 aattaaaccc agaacaaact ctctttttag gtggtttgtc tcgctttgac tttatcaatg
     1861 gggagcgtca agggtttaca gctttttttg acaatcaact agaattacat cgtacaaaat
     1921 tagctggagc agatgctttt tatgataagc atgttggaac tttgttaact ccgccaggta
     1981 agaaagagtt gacagcattt cctaaattag ttcgtcatga atttacaatt gatcagaaaa
     2041 tggatattgt tttttctggt ctaggatgga ttcgtgttaa tggtcaaaaa gactcaaaag
     2101 caatagttgc tgcatgggct cctgaaggcg tcgctgtcat tgttcgtaaa gcgattattt
     2161 aaaaataaaa aaagaagttg gaaaaaaatg cttacaagta aacaaagagc tttcttaaaa
     2221 tctgaggctc atagcttaaa accgattgta caaattggca aaaatggatt aaatgaccac
     2281 attaagacta gtattcgtca agctttggat gctagagaat tgataaaggt cactttgttg
     2341 caaaatactg atgaagatat tcatgaagta gcagagattt tagaagaaga aattgggtgt
     2401 gatacggttt tgaaaattgg tcgtatcttg attctctata aggtttctgc taagaaagaa
     2461 aaccgcaagt tgtcccctaa agttaaagca atctagtcct tttatttgta tagggactgg
     2521 ttttatgaga cgaggactat tgtcgcgaga attttggaga aagtatggca ttagaattgt
     2581 tgacgccttt tacgaaggtg gaattagagg aagaaaaaaa agaaagcaac cgcaaacaga
     2641 ttgggatttt aggagggaat tttaatccta ttcacaatgc acaccttgtg gttgcagatc
     2701 aagttcgcca gcaattagga ttagatcagg tgctattgat gcctgaatgt aaaccaccgc
     2761 atgtggatgc caaagagact attgatgaga agcatcgtct tcgcatgttg gaattggcta
     2821 ttgaagatgt tgaagggcta gctattgaaa cctgtgaact tgaacgtcag gggatcagct
     2881 atacctatga tacgatgctt tatttgactg agcagcatcc tgatgttgat ttttatttta
     2941 tcatcggagc tgatatggtt gattatttgc caaagtggca ccgtattgat gaactggtca
     3001 aactcgttca atttgttgga gttcaacgtc caaagtataa agctggaacc tcttacccgg
     3061 tcatttgggt agatcttcct ttgatggata tttcttctag tatgattagg gattttatta
     3121 aaaaaggtcg tcagcccaat tatctcttac ctaagcgggt tttagactac attactcaag
     3181 aaggtttgta tcaatgacat atgaagatta tcttccttat agcaggaccg aactgttagc
     3241 aaaaattgca gagcagatga gccctaaacg gtttaaacat gtacttggcg tggaaaaggc
     3301 agccttgtcc ttggcagagt gttatggttg taacccagac aaagcagggt tagcagctct
     3361 tttacatgat tatgccaagg agtgccctga ccaggtcttt ttagacttaa ttgacaagta
     3421 ccaattatct ccagaattag ctaaatggaa taataatgtc tggcatggta tggttggtat
     3481 ttataagatt caagaagacc tagggctaaa agacaaagat atcttgcgag ctattgaaat
     3541 tcacaccgtt ggtgctgctg agatgacctt gctggataag gtcttatacg ttgctgatta
     3601 tattgaagaa ggtcgcattt ttcctttggt tgatgacgct agaaaaatcg cgaagctcga
     3661 tttgaatcag gctgttgcct atgaaacagt gaacactgtc gcttatttag cctcaaaagc
     3721 gcagcctatt ttcccacaaa ctctggatac ctataatgcg ttttgcagct atttaaagga
     3781 atactaatgg ataatgatat gaggaataaa atgaaaaaag aagaactctt aaaaattgtt
     3841 gtggaagcaa ctgatgaaaa gcgtgctaaa gatattttag ccttggattt agaggggtta
     3901 actagtttga ctgattattt tgtgattgcg agtgcaacaa atagtcgtca attagaggct
     3961 attgcggata atatccggga aaaggtaaaa gaggctggtg gagatgctag ccatgttgaa
     4021 ggtaatagcc aagcaggctg ggtcttgctt gatttgaccg atgtggtggt acatcttttt
     4081 ttagaagatg agcgttacca ctataatctt gaaaaattgt ggtatgaagc gcctgctgtg
     4141 gctctagatg cctatttagc ttaatgttac aaagagacct tgtcaatacg acagggtttt
     4201 tgaggatgat aatgaaacat aattatgaaa aatttgcgtc agtttatgat gctgtgatgg
     4261 atgattctct atatgacttg tggacagatt tttcacttcg acatttacca aagtctaagg
     4321 gtcgaaatcg tttgttagag ttggcctgtg gaaccggtat tcagtcagtt cgttttgctc
     4381 aagcaggttt tgatgtgact ggtttagact taagtcaaga catgctggct attgctaaaa
     4441 agcgtgcgca atctgctaaa aagaaaattg attttattca aggtaacatg ctggatttgt
     4501 cacaggtggg gcagtttgat tttgtaacct gctattcgga ttccatttgc tatatgcaag
     4561 acgaagttga tgttggcgat gtttttaaag aagtttatga tgttttagca aacgatggca
     4621 tctttatttt tgatgtgcat tcaacctatc aaacggatga gtgtttccct ggttattcct
     4681 atcatgagaa tgcagatgat tttgcaatgg tttgggatac ctatgctgac gaggctcctc
     4741 actctgttgt tcacgaactc actttcttta tccaagaaga cgatggacgt ttttctcgct
     4801 ttgatgaagt gcatgaggaa cgaacgtatg agttattgac ttatgatatt ttgttggaac
     4861 aagcagggtt caagtcattt aaggtctatg ctgattttga agataaggag ccaactaaga
     4921 ccagcaagcg ttggtttttt gtagcatata aatagaagaa aaaagtagcc tttttagcta
     4981 taggatttaa tgaattatct tgaatgttac ttatatgaaa agagttcatt aggcattaaa
     5041 tgctattatc aaagcttaga agtattggag acattacgat tgacactatg tctgaaggtt
     5101 gctaccaact ttaaagaaag cattttctat tatacgttgt gcttaagcat ttgatttaac
     5161 tcttattagc cctataaaag actatttagt acaatttgag gagattctat gactgttacc
     5221 ggaattatag ctgagtttaa tccgtttcac aatggacaca aatatttgct agaaacagca
     5281 gagggactaa aaattattgc tatgtcagga aattttatgc aaagaggaga gcctgctctt
     5341 attgataaat ggattcgatc agagatggct cttaaaaatg gtgcggatat tgttgtggaa
     5401 ttgccctttt tcgtttcagt tcaatcagca gactattttg ctcaaggagc tattgatatt
     5461 ctttgtcaat taggaattca gcaattagca tttgggacag aggatgtgat tgattatcaa
     5521 aaactgatta aggtctatga gaaaaaatca aagcaaatga ctgcctattt atcgacgctt
     5581 gaagatacac ttagctatcc acaaaaaaca caaaaaatgt gggaaatctt tgctggagtt
     5641 aaattttcag ggcaaacgcc aaatcatatt ttggggttaa gttacgcaaa ggctagcgct
     5701 ggaaagcata tacaactatg tcctatcaag cgtcaagggg ctgcctacca ttcgaaagac
     5761 aaaaatcatc tgctagcttc tgcaagtgcc attagacagc acctgaatga ttgggatttc
     5821 ataagtcatt cagtaccaaa tgcaggttta cttataaaca atccccatat gtcatgggac
     5881 cattattttt cattcttaaa atatcaaatt ctgaaccatt ctgatttaac tagtattttt
     5941 caggtcaatg atgaattggc aagtcgtatt aaaaaagcga taaaagttag tcaaaatatt
     6001 gaccacctag ttgacactgt tgctaccaaa cgctatacaa aagctcgtgt aagacgtatt
     6061 ttaacctaca ttttggttaa tgctaaggaa cctactttac ctaaaggaat tcatattcta
     6121 gggtttacct caaaaggaca agcacattta aaaaaattaa aaaaaagcag gcctctgatt
     6181 actagaattg gagcagaaac ttgggatgag atgacacaaa aagcagacag catctatcaa
     6241 cttgggcatc aggatatccc agaacaaagt tttggaagaa tacctattat aataaaaaat
     6301 gagaggctca attaaactct aattgagttt ttttgggggc ttgactctaa cattacgttg
     6361 atggtttata cttcagttaa tccaatgagg aaattttata acaataatta aaaaagtcag
     6421 tcaaaagata tgctttcgaa gaacaggcta acgtttttac aagattatat cagtaatcat
     6481 tttgacaatt gtagtaatgg aatgttgcca aaatttagaa tgttgtgtgt tatgaatgac
     6541 aagattttaa aggaatacta attaaacggg aggtcgtgaa ccggaagctg ttgtcactca
     6601 agcgccaaaa tctgtctgta acataatatt gatgtatggg aacgcaatta tttggttttt
     6661 attgtgatgc ttaaaacgat tttatatttc tattttacca aagcttttca aagtgctata
     6721 ataagggagt tagagtcaat attagtaacg ttaatgttga caatattcaa taaaatacta
     6781 ttaaaaggag acaaaaatgg gacgtaaatg ggcaaatatt gttgctaaaa aaactgctaa
     6841 agatggagca acatcaaagg tctatgccaa atttggtgtt gaaatttatg tggctgccaa
     6901 acaaggcgag ccagatccag agttaaatac agctcttaaa tttgtcattg atcgtgcaaa
     6961 gcaagcacaa gtgccaaagc atgttattga taaagcgatt gataaagcta aaggaaacac
     7021 agatgaaact ttcgtagagg gacgctatga aggttttggt ccaaatggtt caatgattat
     7081 tgtggatact ttgacatcaa atgttaaccg tacagcggca aatgtacgta cggcttacgg
     7141 taagaacggt ggcaatatgg gagcttcagg atctgtatcc tacttatttg ataaaaaagg
     7201 ggtcatcgtt tttgctggtg atgatgctga cagtgtcttt gaacaattac ttgaagcgga
     7261 tgtagacgta gatgatgttg aagcagaaga gggaacaata acagtttata ccgccccaac
     7321 agatcttcat aaaggtatcc aagcacttcg cgataatggt gtagaagaat tccaagttac
     7381 tgaacttgaa atgattcctc aatcagaagt agtattggaa ggtgatgacc ttgaaacttt
     7441 tgaaaagctt attgatgcac tcgaatcaga tgatgatgtt caaaaagtgt atcataatgt
     7501 agcagatttt taaattgaca tagaataata aaaagagttg aaaactattt cagctctttt
     7561 taagtgatgc ttttataagt aagtaccaag taacatagtc gttgttagaa gataatgaac
     7621 aatagtaaat cagtatcaac ttgataggaa tcaattatta gtgaactcta attaaaaatg
     7681 gtaaactaga cacaagaaca aaaaggagag ataggatgat taaaaaacaa tatttaggaa
     7741 gggcaacaat tgccctagca tcaacccttg tactagcagc ttgtgggtca tcaaaaacag
     7801 ctgagtcagg aaatcagggg agttctaaag aagtcttatt tgcaacggtt ggaacaacag
     7861 ctcccttttc ttatgaaaaa ggtggtcaac taactggcta cgatatcgag gtggctaaag
     7921 cagtctttaa aggatcggat gattacaggg tgtcctttaa aaaaacagaa tggtcttcta
     7981 tctttacagg tttggactca ggaaaatacc aaatgggtgg taacaatatt tcctttacca
     8041 aagagcgttc agctaagtac cttttttctt atccaatcgg atcaacacct tctgttttag
     8101 ttgttccaaa agacagtgat atcaagagct ttgatgatat ccaagggcat acgacacaag
     8161 ttgttcaagg gactacaagt gttgcacagt tagaagactt taataagaaa cacagtgaca
     8221 acccggttac tctaaaattc accaatgaga acattaccca aatgttaacc aatttgagtg
     8281 aaggcaaggc agatttcaag atttttgacg ctccaacggt taacgccatt attaaaaatc
     8341 aagggttaga taatctcaaa acaattgaac tcacctcaac agagcaacca tttatttatt
     8401 ttatctttag tcaagatcaa gagaaattgc aaagctttgt taacaagcgt attaaagagt
     8461 tgactgctga cggaactctt agcaagcttg ccaaagagca ccttggcggt gattacgtgc
     8521 catcagataa agagttgaaa cttcctacag ctaactaaac catctattaa ccagttattc
     8581 atctagaaga ctggtttttc tgatcggaaa caatattata gtttatgagg ttatgttata
     8641 aaaattgcaa atagccttaa tcaaaatgag atgttaaagt gctttttgag aagtgaatat
     8701 tgtaagaagt atgctttggg ttttagtcct caaataccaa gttttttgtt gactaaacaa
     8761 ataaggatgg ttagcatagc atatagttta aaactatggt atatgctagc cattatcaat
     8821 ttgaaaacta tatctaatta agatacaata atgatcgtaa acaaaatgaa tcgaggataa
     8881 cgctatgtct tttaaaaaat ggattggaat agtcggaatc gctttagcat caactgtatt
     8941 ggttgcttgt tctgaaaaac aagatgataa aaacactcta actattggag tgatgacaaa
     9001 aacagaatct gatcaagcga gatgggataa agttgaagaa ttattgaaaa aagacaatat
     9061 cactttgaag tacaaagaat ttacagatta ctcgcaacct aataaggcag ttgctaatgg
     9121 tgaagtcgat attaatgcct tccaacacta taatttctta aataactgga ataaggaaaa
     9181 taaggaacat ttggtggcca ttgctgatac ctatatcagc ccaattaacc ttttctctgg
     9241 aaccagtcaa gatgggaagg ctaaatacaa atcagtagct gatctgccaa atggtgctca
     9301 aattgcagta ccaaatgatg cgaccaatga aagccgtgcc ctctatgtgc tgcaatcagc
     9361 tggcctcatt aaattgaatg tgtctggtga tcaattagca accattgcca atatctcaga
     9421 gaacaaaaag aaattagata tcaaggaatt agatgctagc caaacggcac gtgctttagt
     9481 atctgctgat gcagctgttg tcaataatag ttacgctgtt cctgcaaaaa ttgactacaa
     9541 aacctctctt ttcaaagaaa aagcagatga caattcaaaa caatggatta acattattgc
     9601 aggtcaaaaa gattgggaaa aatcagagaa ggctgatgct attaaaaaac tcatcaaggc
     9661 ctaccaaact gatgaggtga agaaagtcgt ggaaaaaact tcaaatggta tagatgtatc
     9721 cgtatggtaa attttagcca ttgttataac aagagtgtgg tcgtgtttaa aacacatgct
     9781 ttcttgcatg cttgaggaag agtttacgac taatttacct ttagaaagct atttaagacc
     9841 ttttcccttt taggatttag aaaccttggg aagactattg catgttatct taatagtcat
     9901 gattatgcag gcgatgaaaa cattgctatc gtagattact gtcgccatat cgtactaata
     9961 gaggagttat taaaatctta tgaatgaagc aataattcaa ttagatcata ttgatattac
    10021 cttccgtcaa aaaaaacggg ttatcgaagc tgttaaagat gtcacggttc atatcaatca
    10081 aggagatatt tatggcattg ttgggtattc aggtgccggg aaatcaactc ttgtgcgtgt
    10141 gattaacctg ctacaggcac caacaaacgg gaaaatcact gttgatgggg atgtgacctt
    10201 tgaccagggg aaaattcaat tgtcagctga tgcccttcgc caaaaacgac gtgatattgg
    10261 tatgatcttc caacatttca atttgatggc ccaaaaaaca gccaaagaaa atgtagcatt
    10321 tgcgctccgt cattcgtcgt taagtaagac tgagaaagaa cataaagtta tcgagctgct
    10381 agaacttgta ggtttatcag agcgagcaga taactaccct gcccagttat cgggtgggca
    10441 aaaacaaagg gtggctattg cgcgtgctct agctaacgat ccaaaaattt tgatttcaga
    10501 tgaggcaaca tcagcactag atccaaaaac cactaaacaa attttggcgc tcttgcaaga
    10561 attaaaccgc aaacttggcc ttaccattgt tatgattact catgaaatgc aaattgttaa
    10621 ggatatttgt aatcgtgttg ctgttatgca aaatggtgtt ttgattgaag aaggttctgt
    10681 ccttgatatc ttttcaaatc caaaagaagc cttgacacag gaatttatca caacagctac
    10741 agggattgat gaggctttag aaaaaattaa ccaacaagac attgttaaac atttgcctgc
    10801 aaatgccctt ctagctcagt tgaaatatgc aggaacttct acggatgagc ctctacttaa
    10861 tagcatttac cgtcaatttg aagtgacagc taatattttg tatggcaata ttgagatttt
    10921 agatcatatt ccagttggtg acatgattgt tgtcttggaa gggcaagctg aaaatattct
    10981 tgcggctgag aaagccttgc atgaagctgg tgttgatgtt agtattttaa agagaggagc
    11041 ctagatgtca cagttaattc aaacttattt gccaaatgtt tatgaactcg gatggtctgg
    11101 agatgctggt tggggcttag cgatttggaa tactttatac atgaccattg tgccttttat
    11161 tgttgggggt gctattggtc tcttattagg cttattatta gttttaacag gaccggacgg
    11221 tgttattgaa aacaaaacga tttgttgggt tattgataaa gttacctcta tttttagagc
    11281 cattcctttt gttattttga ttgctatttt agctagcttt acctatttgc ttttaagaac
    11341 aactttagga gcaacagcgg ccttggtacc tttaaccttt gcgacttttc ctttttatgc
    11401 ccgtcaggtc caagttgttt tttcagaatt agacaagggt gttattgaag cagcgcaagc
    11461 ttcaggtgct actttctggg atattgtcaa agtgtatctc agtgaaggtt taccagatct
    11521 tattcgtgtt tctacagtca ccttaatttc tttagttggg gaaactgcca tggcaggagc
    11581 tatcggtgct ggaggattag gaaatgtagc gatttcttat ggttataatc gttttaacaa
    11641 tgatgtgact tgggtagcga ctattattat tcttttaatt atttttgcta tccaatttat
    11701 tggtgatagc ttgactagaa ggtttagtca taaataaacg aaacaacacc ctaagttttt
    11761 acttagggtg ttgttgttta gatgatgtca ttagcttttc ttcgttttac ttagtataag
    11821 ccctattaaa aaaccaatag cagcaaagat aatccatccc attgagaatt gccctagtgg
    11881 aacagttttt tggaaaaaag ttacaacggc ttctggtaaa tgaaataatc cagtcatttg
    11941 tgatagtgtt aggagtgcat caaatatggc aggaataaag gttagaccaa ttgtagttcg
    12001 atagacaata ggatcattat tgaagcattt ttgtgccaaa acaaggaaaa ttaaatcgac
    12061 tgttaatggg tataaaagga ataaaacagg agctgaccag ttgataataa ctgataaacc
    12121 accaaaataa aagaaagctg atagtaaagt aaagatagtt gcccaagcaa tatgagataa
    12181 agcaggcact aatttatgga agtattcagc acttgacgtg attaagcctg ttgaagtggt
    12241 tagacaggcc aggaaaatca caacagctag aaatgcttgt ccgatgccac ctaggtaaaa
    12301 acgagaagca tgacttaaga tttgaccgcc attaactgga ttaccatgaa gggtaaagct
    12361 gccatcacta aaaggaaata atgattgtga tgttgctcca atacgaccga caaagatata
    12421 gacaagtgct aatagcaaaa tggcaatagc cccagaaata agtgttattt tggtcacttc
    12481 tttgtccgtc ttagcgccaa attgtttggt agcctcaatg actaaaatag caaaaacaag
    12541 agaagctagt gcatccatag tgccataacc ttgaattaat cctgctataa aaggaaaatc
    12601 tttaaaggca ttattaacac cgaccccagc gttaaaagca tcaccgtaat ttccagcagg
    12661 atggacaaag gacgcgataa ccaaaataga aataacaact aacaacgttg gcgttaaaaa
    12721 ttttccgata ttttcagcta gcttactagg tttgatagca aggaagtagg acagaccaaa
    12781 aaatagtata gcataaatag ctttattggt tgtattatct cctaagatag gagcgatacc
    12841 gactgaaaaa gaagtggctc ctgttcttgg aatagcaaaa aatggaccaa tagataaata
    12901 caaaatggaa gaatagaaga ttgcatacca tttagagatg gggcgtgcca aactttcaac
    12961 atcgcctgat ccagatttag caacagcaat gacaccgagt aaaggcaagg agacaccagt
    13021 taaacaaaaa ccaatgatag accatagaat ctgatgacct gagtagatgc ctaaaaaagc
    13081 tgggtaaatg aggtttgctg ctccaaaaaa tagtgcaaat agcatgaatc caatgacgat
    13141 atatacattt ttttgtttca tttata
//
LOCUS       DATWEK010000040        12432 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.040, whole genome shotgun sequence.
ACCESSION   DATWEK010000040 DATWEK010000000
VERSION     DATWEK010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12432
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.040"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..509)
                     /gene="speG"
                     /locus_tag="VCR92_001520"
     CDS             complement(<1..509)
                     /gene="speG"
                     /locus_tag="VCR92_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeG"
                     /protein_id="HEP4268575.1"
                     /translation="MKTNILTIIILSCVFSYGSQLAYADENLKDLKRSLRFAYNITPC
                     DYENVEIAFVTTNSIHINTKQKRSECILYVDSIVSLGITDQFIKGDKVDVFGLPYNFS
                     PPYVDNIYGGIVKHSNQGNKSLQFVGILNQDGKETYLPSEAVRIKKKQFTLQEFDFKI
                     RKFLMEKYN"
     gene            complement(611..709)
                     /gene="ffs"
                     /locus_tag="VCR92_001521"
     ncRNA           complement(611..709)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VCR92_001521"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            909..2141
                     /locus_tag="VCR92_001522"
     CDS             909..2141
                     /locus_tag="VCR92_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEP4268576.1"
                     /translation="MGVMMKQKIKILTVIGLMTVGMSACHNTSKPSNTDSVFSLTGKK
                     RQQIVKQVRQRYYFQQLSKTEQENYLTLYDSLAQFREIISLTPASKKSLIKTIDAFVM
                     DNPEFYWITSADYRFEFSDQTVFVTFPIPEDAKNVYQDLQAIGNDIVANTPSKDRYEQ
                     VKYFYEVIIRDTDYNKKAFEAYQSGSQAQVASNQDIKSVFIDHLSVCNGYAQAFQFLC
                     QKAGIPVAYIRGTGTSQQPQQSFAHAWNAVQINNTYYGVDVTWGDPVFDNHLSHQKQG
                     TINYSFLCLPDYLMALSHQPSKDIAFNTKERFENVWTIPSCTDDSLLYSKRHQSYIST
                     FDSDAILASLENQLLNRQEQLCLQFAHQDDYQQMVTDLTTNQTGYHNLFNQYWNNYTG
                     FTYGLLPETLSISFASRN"
     gene            complement(2755..3270)
                     /locus_tag="VCR92_001523"
     CDS             complement(2755..3270)
                     /locus_tag="VCR92_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEP4268577.1"
                     /translation="MPYSLEEQTYFMQEALKEAEKSLQKAEIPIGCVIVKDGEIIGRG
                     HNAREESNQAIMHAEMMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     IYGASNQKFGGADSLYQILTDERLNHRVQVERGLLAADCANIMQTFFRQGRERKKIAK
                     HLIKEQSDPFD"
     gene            complement(3270..4049)
                     /locus_tag="VCR92_001524"
     CDS             complement(3270..4049)
                     /locus_tag="VCR92_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEP4268578.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNEL
                     EKEISPLDLDAVIISHYHPDHVADLGVLRHYFQLYPKHLWQPKVLPIYGHDEDRHEFA
                     KLSIPDVSEGRAYDVTGVEQIGPFDITFLKTVHPVVCYAFRIVERATGQVLVFTGDSG
                     YFEGLADFAKEADLFLADVYLYEGNENHMAHLTSKEAGLMASQAGVKKLVLTHMPPVP
                     PEGIDPDNHLEVLRQETQAYAGNIPVDLALPHKSWNLGSLS"
     gene            complement(4192..4728)
                     /locus_tag="VCR92_001525"
     CDS             complement(4192..4728)
                     /locus_tag="VCR92_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEP4268579.1"
                     /translation="MFTTKELVKVAMMTTLIIILGFIPAIPLGFIPVPIVLQNLGVML
                     AGLMLGGKKGTLSVFLFLVIGLFLPVFSGSRTTIPVLMGPSAGYVIAYLLVPIVFSLL
                     YRNWFSKSTPLAFLALLISGVVLVDVLGAIWLAAYTGMSLVTSLLSNLVFIPGDTIKA
                     IIATIIAVKYKDSFLNTK"
     gene            complement(4732..5043)
                     /locus_tag="VCR92_001526"
     CDS             complement(4732..5043)
                     /locus_tag="VCR92_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268580.1"
                     /translation="MTDCFGIDLDQEYRCLHYHTPLDIVGLKCAFCQTYYACYHCHDQ
                     LTDHAFVPTGHQETSPVICGHCRKLLSLAEYGCGCCPYCQSPFNPACHRHKDIYFLKE
                     S"
     gene            complement(5260..6402)
                     /gene="tgt"
                     /locus_tag="VCR92_001527"
     CDS             complement(5260..6402)
                     /gene="tgt"
                     /locus_tag="VCR92_001527"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEP4268581.1"
                     /translation="MTDYPIKYRLIKTEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKAIGSGIILSNTYHLWLRPGDELIARSGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVAMDFPGYSI
                     GGLAVGESHEEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVIKNAKFAEDFTPLDHDCDCYTCQNYSRAYIRHLLKADETFGIR
                     LTSYHNLYFLVNLMKKVRQAIMDDNLLEFRQDFLERYGYNKSNRNF"
     gene            6621..7484
                     /locus_tag="VCR92_001528"
     CDS             6621..7484
                     /locus_tag="VCR92_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEP4268582.1"
                     /translation="MSIKAIKGQARDTLKNLSGKYLLFLIPTLLFMFHFGIEIHQGYV
                     LSSGIEVSLAASYFPLLLGVILSLFILSASFTMIDVVRHFRQKVSFAESTTAFSKEFF
                     GNLLVLAITKWLFFLIWSLIWFFGLFIFLSGLSAFLVNAKSGGSTVISLIFLLFGAVL
                     SLIGFGIYINRYYAYSLSEYLLYDKVKEGTYLGAIAVIETSVAMMKGYKWKLFFLQLS
                     FTGWFLLNIVTFGLLNIYLLPYFTTANVIFYDQLKKRFKDKDDPIEGEHLSLHQLNKK
                     PTPMMYDDQKD"
     gene            7570..8912
                     /locus_tag="VCR92_001529"
     CDS             join(7570..8020,8020..8912)
                     /locus_tag="VCR92_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEP4268583.1"
                     /translation="MKFNQETKVKIYELRQMGESIKSISKKFDMAESDLKYMIRLIDR
                     YGVTIVQKCKNNYYSPELKQEIINKVLIDGQSQKQTSLDYALLTSSMLSRWIAQYKKN
                     GYTILEKPRGGPSKMGRKRKKNLEEMTEVERLQKELEYPRAENAVLKKPERIPLEGRS
                     KAQRATEIIQALRNQFPLEMLLEILDLSRSTYYYQVKRLAQGDKDIELKHVIREIYDE
                     HKGNYGYRRIHMELRNRGFVVNHKKVQRLMKVMGLAARIRRKRKYSSYKGEVGKKADN
                     LIKRHFEGSKPYEKCYTDVTELALPEGKLYLLPVLDGYNCEIIDFTLSRSPNLKQVQT
                     MLEKTFPADSYSGTILHSDQGWQYQHQSYHDFLESKGILPSMSRKGNSPDNGMMDSFF
                     GILKSEMFYGLEKSYKTLDKLEEAITDYIFYYNNKRIKAKLKGLSPVQYRTKSFQ"
     gene            complement(9212..10084)
                     /locus_tag="VCR92_001530"
     CDS             complement(9212..10084)
                     /locus_tag="VCR92_001530"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEP4268584.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLASGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDRIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGV
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            10308..11618
                     /locus_tag="VCR92_001531"
     CDS             10308..11618
                     /locus_tag="VCR92_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEP4268585.1"
                     /translation="MIHLIIISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLIAT
                     LLSALGAGFFTTMAICCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSGSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYIRYSKGRTNSSLTIDQPPVLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRQTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWAIIIMLCGMSLLMSLAVKSGLVTLIGHLITTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPTLFPIIATISTQSPHIDIRLLTTATIIGALSTNISPFSSAGSL
                     IQLSLPHIEERSLAFKKQILLGVPISLSLALLTIWILMLLASLS"
     gene            11696..11989
                     /locus_tag="VCR92_001532"
     CDS             11696..11989
                     /locus_tag="VCR92_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEP4268586.1"
                     /translation="MPRKTFDKAFKLSAVKLILEEEQSVKMVSSTLEIHPNSLYRWIQ
                     EYEKYGESAFPGHGSALRHAQFETKKLEKEHKLLQEELALLKKFQVFLKPNRK"
     gene            12022..12318
                     /locus_tag="VCR92_001533"
     CDS             12022..12318
                     /locus_tag="VCR92_001533"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEP4268587.1"
                     /translation="MNSHHTCQTLQVSRSGFYAYLKRRLSSKHVENEALKEMIKDIFY
                     EHKERYGSVRITQELCRRGIHVNHKRVGRLLHQLGLYAKGSRYQYKYYNRRRSS"
BASE COUNT         3862 a         2591 c         2246 g         3733 t
ORIGIN      
        1 atattgtatt tttccattag aaattttctt attttaaaat caaattcctg taaagtaaac
       61 tgtttctttt ttatgcgaac agcctcagag ggcaaataag tttctttccc atcttgattt
      121 aaaattccta caaactgtaa tgatttattt ccttgattcg aatgttttac aataccacca
      181 taaatattat ctacataagg tggggaaaaa ttataaggga gaccaaaaac atcgacctta
      241 tcccctttta taaactgatc agtaatgcct aaagatacaa tagaatcaac ataaagaata
      301 cattccgatc ttttttgttt agtattaata tgtatgctat ttgtagtaac aaatgcaatt
      361 tctacatttt cataatcgca tggggtaata ttataggcaa accttaaact tctttttaaa
      421 tcttttaaat tttcatctgc ataagctaat tgacttccat agctaaaaac acatgataat
      481 atgataattg tcaaaatgtt tgttttcatt taaaactttt tatgtcctgt tttatacctc
      541 ttaacctaaa taaaaatatc aatcggtttc aacaactgat gacactatag aaggaggaga
      601 ttactttagt aaagtcaaca aaaaaagagc acacacccga aaatcgctta gggctgctgg
      661 attcctcccc tgacccactt cacgcacaag tgttgctccg cctattatta tatcatatta
      721 cggacagttt gcaagttttc caactaagta aaatcacttt caagtgagca tagcttcatt
      781 ttgggacaag atggactgaa tacctagaaa aatcatgacc ctttccaaac acgattttgc
      841 tttttgaaaa tctttccctc tccccattcc agctattctc tatgttataa taagattatt
      901 agattagaat gggagttatg atgaaacaaa agattaaaat cttaacagta attggcctta
      961 tgacagttgg tatgtctgcg tgtcacaaca ctagcaaacc ttctaatacc gattctgttt
     1021 tttctttaac cggaaaaaag cgccaacaaa tcgtcaaaca agtaagacaa cggtattatt
     1081 tccaacaatt atccaaaacc gaacaagaaa attacctcac tttatacgat agtctagcac
     1141 aatttcgtga aatcatcagt ttgacgccgg cttctaaaaa aagcttaatt aaaacgattg
     1201 acgcctttgt gatggataat cccgaatttt actggattac atctgccgat tatcgatttg
     1261 agttttctga tcaaacggtc tttgtcacct ttcctatccc agaagatgcc aagaacgttt
     1321 accaagactt gcaagcaatc ggtaatgata tcgtcgcaaa cacgccatca aaggatcgct
     1381 atgagcaggt caaatatttt tatgaggtca tcattcgaga cacagactac aataaaaaag
     1441 cctttgaagc ctatcaatca ggcagtcaag cccaggtcgc ttctaatcaa gacattaaaa
     1501 gtgtttttat tgatcattta tctgtttgta atggctatgc ccaagccttt cagtttcttt
     1561 gtcaaaaagc tggcattcca gtcgcctata tccgtggaac tggtacatct cagcaacctc
     1621 agcaatcttt tgcacatgca tggaatgctg ttcaaattaa taacacttat tatggcgttg
     1681 atgtcacttg gggtgaccct gtttttgata accatctctc acatcaaaag caaggaacta
     1741 tcaattacag ttttctatgc ctgccagatt atctaatggc cttatcacat cagccaagca
     1801 aagacattgc ttttaatact aaagaacgtt ttgaaaatgt ttggactata ccttcttgta
     1861 cagatgattc tttgctttat tctaaacgtc atcaaagcta tatctcaacg tttgacagtg
     1921 acgccatcct tgcaagcctt gaaaatcagt tgttaaatag acaagagcaa ctatgtctac
     1981 aatttgctca tcaagatgat tatcaacaga tggtaactga tttaacgacg aatcaaacag
     2041 gttatcataa ccttttcaat cagtattgga ataattatac gggctttacc tatggactct
     2101 taccagagac tcttagtatt tcatttgcta gtaggaacta ggtttagaca catgaaacac
     2161 aaagttaaga tgattatctt tgtcaaacat tacaagaaat tgatatactg acacaattga
     2221 aggcgattat tattctaacc gtcttcaata gatataacct tttcagattg agcacatcta
     2281 atgcttgtaa cattagcaac agtgatgagc tcttttttaa tgctttagca aaatatatca
     2341 gctaagacaa aagattaaat aactcaagcc atgcctataa gtcacttgtt tttaatccct
     2401 gtgtcagtgt caatctacgc cacagataac tgacagctct gagccttaga agtctgagct
     2461 ggataagttt actaaaaaca aaaataaggt gagccattac tatctgtttt tagatagtaa
     2521 atctttttaa gaatgactaa ctcatctagt catcacgtgt tttatttttc gattgttttc
     2581 acctcgattg ggtctgaaaa agagcgcttc tagtacttgg aaacgccctt ttgtatattc
     2641 tatcttcgta tgttgaatct aacaaccatt ggaaaaatgg tctaacgttt cactcattat
     2701 tttgacaggt tacccttcac caaaaatgca tgtgataaca agctccttaa aactctaatc
     2761 aaagggatct gactgttcct tgatcaaatg cttagctatt tttttgcgct ctcgcccttg
     2821 gcggaaaaag gtttgcatga tattagcaca gtctgctgct agcaggcctc gttcaacttg
     2881 tacgcggtgg tttaagcgct catctgtcaa aatctggtaa aggctgtctg ctccaccaaa
     2941 tttttgattg ctggctccat aaataacatg cggaatcctt gctagcccaa tggcaccact
     3001 acacatcaca caaggctcga tggtcacaaa gagtgtggtg tctaataaac gccagttgcc
     3061 ttcatgagcg ttagcctcgt taatggccat catttcagcg tgcataatgg cttggttact
     3121 ctcttcacgc gcattgtgcc cacgaccaat aatctcacca tccttgacaa tgacacagcc
     3181 aatggggatt tcagctttct gtaaggattt ttcggcttct tttaaagcct cttgcatgaa
     3241 ataagtttgc tcttctaaac tatatggcat caagaaagac tccccaagtt ccaagatttg
     3301 tgtggtaagg caaggtcaac aggaatatta cctgcatagg cttgtgtttc ttgcctcaac
     3361 acttccaagt gattgtcagg atcaatacct tctggaggaa ccggtggcat gtgggtcaag
     3421 acaagcttct taacacctgc ctggctagcc attagtcctg cttccttact ggtcaaatgg
     3481 gccatatgat tttcattgcc ttcgtataag taaacatctg ctaagaaaag gtctgcttct
     3541 tttgcgaagt ctgccaatcc ttcaaaataa ccactgtctc cagtaaagac aagtacctga
     3601 ccagtcgctc tttctacaat tcgaaaggca taacacacaa ctggatgaac tgttttaaga
     3661 aaggtaatgt caaaaggacc aatctgttca actccagtga catcataggc tctaccttct
     3721 gaaacatcag gaatgcttaa cttagcaaat tcgtgtcggt cctcatcatg cccataaatg
     3781 ggcaatactt taggctgcca caggtgttta ggataaagtt gaaaataatg gcgcaacacg
     3841 cctaaatcgg ccacgtggtc tggatggtaa tggctaataa tcactgcatc caaatcgaga
     3901 ggactgattt ctttttccag ctcattgagc gctcgactac cagcatccat caataactga
     3961 aagccgtcat gtcctgtgac caaataagag gttgtgcctg catcttgata gggataggct
     4021 ccccaagacc ctaaggtggt taatttcatc tcaaaccctt ctttcttgct ttaactctta
     4081 ttataacaaa aattagtgtc aaagaggatt gagacccacc aaaaacaggt cctagcagat
     4141 aaatctgcca agacctgttc aacacaactt aactatttga tgattagatt actattttgt
     4201 attcaaaaaa ctatctttgt atttaacagc gataatggtc gcaatgattg ctttgatggt
     4261 atctcctgga ataaagacca agtttgacaa aagcgatgtc acaagagaca tgccagtgta
     4321 ggctgccaac cagatagcac ccagaacatc aaccagtaca actcctgaga ttaaaagagc
     4381 taggaatgcc aatggcgtgc tttttgagaa ccagttgcgg taaagtaatg aaaagacaat
     4441 aggcacaaga aggtaggcaa taacatagcc agcagatggc cccatcaata ctggaatggt
     4501 tgttcgtgag cctgagaaaa caggtaagaa aaggccaatc actaaaaata agaaaacaga
     4561 taaggttccc tttttaccac ccagcatcaa tccagccaac atgacaccta agttttgtaa
     4621 aacaataggg actgggataa agcctagcgg gatagcagga ataaagccta aaataataat
     4681 caaagtggtc atcatagcca ccttaacaag ttctttggtt gtaaacatct gttacgactc
     4741 ctttaaaaaa tagatatcct tgtgcctatg acaggctgga ttaaagggac tttgacaata
     4801 aggacagcat ccacaaccat actcagctag gctcaagagc tttcgacaat gcccacaaat
     4861 aacaggagat gtttcttgat gtcctgttgg cacaaaggca tgatctgtta actggtcatg
     4921 gcaatggtag caagcataat aagtctgaca aaaagcacat ttgagcccaa caatatcaag
     4981 cggggtatga taatgtaggc accgatactc ttggtcaagg tcaattccaa aacagtccgt
     5041 catatctcat cctcttgtaa cagtttaatc aaaagcatat gatttgtcaa ctctattttt
     5101 acaaaagggt aactgttttc tgaaaaagaa cacgtaaaac aagaacttcc ctttaaagag
     5161 ggacctatca gttgaaagca ataggacatc cgtctataca aaaaaactga aaccaaagac
     5221 gatagatcgc cctcagttcc aggatcatag catttttaat tagaaattac ggtttgattt
     5281 attataacca taccgttcaa gaaaatcttg gcggaattca agtaagttat cgtccataat
     5341 agcctgacgt acttttttca tcaagttaac caagaaataa aggttgtggt agcttgtcaa
     5401 acgaatacca aaagtttcgt ccgcttttag caagtgacga atgtaggcac ggctatagtt
     5461 ttgacaagtg tagcagtcac agtcatgatc aagtggggta aaatcttcag cgaatttggc
     5521 atttttaatc acaagacgcc cctcactagt catgcaagtt ccgttacggg cgatacgcgt
     5581 tggcaagaca cagtcaaaca tatctacacc acgaatcaca ccatcaatca agctatctgg
     5641 tgctcccact cccatcaggt aacgaggttt attttctggt aagaggggag tcgtaaagtc
     5701 aaggacggca ttcatttctt catggctctc cccaacagct aaaccaccaa tagaataacc
     5761 tgggaaatcc atagccacca aatctgccgc agactgacga cgaaggtcct caaatccagc
     5821 tccttgtaca attccaaata atccttggtc atgaggacga cgatgggctt ttaagccacg
     5881 ttctgcccaa cggctagtac gttcaatgga ttttttcacg taatcataag gttggtaaaa
     5941 ttgcgggcac tcgtcaaaac tcatcatgat gtctgagcca aggttattct gaatggaaat
     6001 ggctttttcg ggtgatagaa acatttttga gccattcaag tgatttttga aagtcactcc
     6061 ttcttcagtg atgtttcgtg aatcggctaa agagtaaact tgaaaaccac ccgaatcggt
     6121 taagattggc tgatcccagt tcataaactt gtgcagacca ccagagcgag caatcaactc
     6181 atctcctgga cgcaaccaaa ggtgataagt gtttgataaa ataatccctg atccaattgc
     6241 ttttaactct tctggagact gtgttttaac agtagcctga gttcccactg gcataaacat
     6301 tggtgtcgga aaggtcccgt gaggggtgat aatttcgccc aagcgtgcac cggtgtgctt
     6361 ttctgttttg ataaggcgat acttaatcgg ataatctgtc atgtgctttc ttccttgcta
     6421 tcaagataaa cagtcttgag cttttttgat ctgcctgagt ttccatcata atgaagggct
     6481 tcaagatgac atgttgttct agcgcctatc attttatcaa aaaatccata atttgtcatg
     6541 ctttcccaaa aaagtatagt caaaataatg gttagctgtc tcattttgtt ttatggtata
     6601 atgaaataaa ggagtctgtt atgtcaatta aagcaatcaa aggccaggct agagacacgt
     6661 taaaaaatct ctctggcaag tatttactat ttttaattcc aacccttctc tttatgtttc
     6721 atttcggtat tgagattcat caaggttacg tcctatctag tggtattgaa gtctcgctag
     6781 cggctagtta tttcccatta ctactaggag ttatccttag ccttttcatt ttatcagcat
     6841 cctttacaat gattgatgtt gttaggcatt ttcgtcagaa agtttctttt gccgaatcaa
     6901 caacagcctt ctcaaaagaa ttctttggga acctgctggt tttagcgatc actaagtggc
     6961 tattctttct catctggtca ctaatttggt tttttggcct ctttattttc ctttccggac
     7021 tttcagcgtt tttggtcaat gctaaatcag gtggctcaac agtcatttca ctgatctttt
     7081 tactatttgg agcagttttg tccttaattg gttttggtat ttatatcaac cgttattacg
     7141 cttatagtct atcagaatac cttctctacg ataaggttaa agaggggact tatctaggag
     7201 ctatagccgt cattgaaaca agtgtagcta tgatgaaagg ttataaatgg aagctttttt
     7261 tcttacaact tagcttcacc ggttggtttc tactgaatat tgttactttt gggttactta
     7321 atatctatct tttaccatat tttacaacag ccaatgtcat tttttatgat caactcaaga
     7381 aacgtttcaa agacaaagat gacccaattg aaggagaaca tttaagcctt catcagctta
     7441 ataaaaagcc tactcctatg atgtatgacg atcaaaaaga ctaaataaat cctccatcca
     7501 taaaaatagc ccttgaactg caccccaaaa gttagacaca aaatctaacg attggggtgc
     7561 tattttttta tgaaatttaa tcaagaaacg aaagttaaga tttatgagtt acggcaaatg
     7621 ggagagtcca ttaaatccat atcaaaaaag tttgatatgg cagaatccga tctcaaatat
     7681 atgattcgct tgattgatag gtatggggta accattgttc aaaaatgtaa gaataattat
     7741 tattctccag aactgaagca agagataata aataaagtcc tgattgacgg ccaatctcag
     7801 aaacaaacat ccttagatta tgctttacta acttctagta tgctctcaag gtggatagcg
     7861 caatacaaga aaaacggtta tactattctt gaaaaaccaa gagggggacc gagtaagatg
     7921 gggcgtaaac gtaagaaaaa tttggaagag atgacagagg ttgaacgtct tcagaaggaa
     7981 ttagaatacc ctagagcgga gaatgctgtg ctaaaaaagc tgagagaata ccgcttgagg
     8041 gacgaagtaa agctcaaaga gcaacagaaa tcattcaagc attaaggaat caatttccct
     8101 tagagatgct acttgagatc cttgatttat cacgctccac ctattactat caagtgaagc
     8161 gactagctca aggagataag gatatagaac taaagcatgt gattcgagag atttatgatg
     8221 agcataaagg taattacggt tatcgtcgta ttcatatgga gttgcgtaac cgaggatttg
     8281 tggtcaatca taagaaagtt caacgtctca tgaaagtcat gggcctagca gcccgcattc
     8341 gtcggaagcg caagtattct tcttacaaag gagaggttgg taagaaggct gataatctga
     8401 ttaaacgtca cttcgaaggc tctaaacctt acgaaaaatg ttacactgat gtgacggagt
     8461 tggccttacc tgaaggaaaa ctctacttat tacctgttct tgacggctat aactgtgaga
     8521 ttattgattt cactctgtct cggtctccta acttgaaaca ggttcaaacc atgcttgaga
     8581 agacttttcc agcggattca tacagcggaa ctattcttca tagtgaccag gggtggcaat
     8641 accaacacca gtcctaccat gattttttag agtctaaagg tattctgcca tccatgtccc
     8701 gcaaagggaa tagcccggat aacggcatga tggattcctt ctttggcatt ctcaaatctg
     8761 aaatgtttta tggactcgaa aagtcttata aaacccttga caagcttgaa gaagctatta
     8821 cagattacat tttttactac aacaacaaac gaatcaaagc aaaactaaaa ggacttagtc
     8881 ctgtccaata cagaactaaa tcctttcaat aattatttgt ccaacttttt ggggtcagta
     8941 cactcctagt taacgacttt gattgatttt attatgatga atcgtgattt ctgaaaacaa
     9001 aattttcttc atggatttgg cgtggaactt ttacaataaa aacactaacc tctccctatc
     9061 gttttttcag gtgaatgctt ggaattggta taataagcgg acacgaatca ggtgaaaaca
     9121 gagaaagtat ttgaagaggc gtttaaacta tctgacataa aactcgttct agaggaaaga
     9181 catcctttaa aaagttagtt tattttgcaa cttagacatc aaggtaggtt aaacccttca
     9241 tggaaaaatc gagactctta gcactatggg ttaaactacc actggagacg taatcaatcg
     9301 ctaaaccacg aaaacggcta atagtggtca tatcaatatt tccagaacat tcaatccgag
     9361 aacgtcctgc aattagagta atggcctgtt caatctgttc caatgacata ttatccaaca
     9421 tgataatatc aacacccgcc gccgcagctt cttcggcagc agcaagactt tccacttcca
     9481 cctcgaccat tttcacaaaa ggggcatagg cacgcgcttg agcaatcgcc ttttgaacac
     9541 tacctactgc cgcaatgtga ttgtctttta gcatgatagc atctgataaa ttaaagcgat
     9601 gattatagcc accgccaact ctcacggcat atttctcaaa aagacgtaaa ttaggagtgg
     9661 tttttcgagt atcaaatacc ttaatgcgat catcgcctaa ggcttctaca taagcagctg
     9721 tcatcgaagc aatccctgat aaatgttgta aaaaattcaa ggcaacgcgt tcacatgtta
     9781 agaggcttct caccgagcct atgatttcta aaaccaaatc gccactagcc aaacgatctc
     9841 catccttaaa ttgatgagga ttctggaagg tcacctcggc atcaaatagg gtaaaaaccc
     9901 tttgaaaaac ggttagcccc gctaaaacac cagcttcctt ggcaaaaagc gacaccttgg
     9961 cttggccatg atgatcaaaa atggcattgg tactgtaatc ttcggaatga acatcttctc
    10021 gcaaggctgc tttcaatgta tcatctattt gaaaaggggt taaatcagtt gaaatgattg
    10081 acatcactaa gtcctctatt tttaatatca cttgtaagca ctagaggcaa ttgctattaa
    10141 cttccgtagg aaatcacaaa cctgaatacc tcgttttaaa ttccaacaag tgtcaagaca
    10201 attgtaattt ttttgtgtat aatagtcaag taccaatagg aaacaggtgg tcttttgagc
    10261 gccaaaattg ccaacctatt tacatattct aactaaagga caattcaatg attcatttaa
    10321 taataattag cgccattgct ctagccattg gaattggtta ccgcaccaaa atcaatattg
    10381 gcctactggc tattgctttt tcttacctca tcgcaaccac tctcatggga ttaagcccca
    10441 aagaacttct tcatttttgg ccaacctcac tcttttttac catttttagc gtctctctct
    10501 tttataacgt tgcaacaact aacggcactc ttgatgtttt ggctcaacac attctctacc
    10561 gcacacgcac ccaccctaac gccctctaca tgattttata cctgatagca acccttttgt
    10621 ctgctttagg tgctggattt ttcactacta tggccatttg ctgtcctcta gcgattaccc
    10681 tctgtcaaaa agcggacaaa caccctttga ttggagctca agccgtcaat tggggagctt
    10741 caggaggggc taatttgata accagtggct caggcattgt ctttcaaggc ctgtttaagc
    10801 aaatgggatg ggaagagcaa gctttttcac ttggcaatca tatctttatc gtcagcatta
    10861 tctacccact catcgtcttg cttttattat cttgttacat ccgctacagt aagggaagaa
    10921 caaactcatc cttgactatt gaccaaccac cagtcctcag caaggtccaa agacaaacca
    10981 ccttgctcat gatcagcagc atggttttgg tttggctttt tcccttgttg catctcattt
    11041 tcccaaacat cgcatggata gctacttatc gacaaacatt tgatattggc tttgtctcaa
    11101 tactcatggt ctgcctcgcc ttaaggctca aattagggaa gcaagaagcc attttggcta
    11161 aggttccctg ggctataatt atcatgctct gcggcatgag cttactaatg tctctagcgg
    11221 tcaagtcagg tttagttaca ctgatagggc acctcataac aacaaccatt cctcatttct
    11281 ggttacctct gttcttttgt gtgatagccg gagtgatgtc actctttagt tccaccctat
    11341 ccgttgtagc cccaactctc tttcccatca ttgctaccat cagtactcaa agtcctcaca
    11401 ttgatattcg cttactcaca acagccacta ttattggcgc tctatctact aatatctctc
    11461 ctttttcatc agctggttcc ctcattcaac tctcccttcc ccatatagag gaacgcagtc
    11521 ttgctttcaa aaaacaaatt cttctgggtg tgcccatcag cttaagtttg gcactcttga
    11581 ccatctggat tctcatgctg ctagcttcct taagttagat ttattgtcta acatttggtt
    11641 ggacttggta tactaaagta gacacaaaat taagtggaaa cgaggaatag tcattatgcc
    11701 aagaaaaacc tttgataaag ccttcaaact ctctgctgta aaactcatcc ttgaggaaga
    11761 gcagtctgta aaaatggtta gttcaacttt agaaattcat cccaatagtc tttatcgatg
    11821 gattcaagaa tatgaaaaat atggagaaag tgcgttccca ggacatggga gcgcacttcg
    11881 tcatgctcaa tttgagacaa aaaaacttga aaaagagcac aaactgctac aggaggaatt
    11941 agctcttcta aaaaagttcc aggtcttttt gaagccaaac cggaaataaa atttcagttt
    12001 ctgaaggaaa atagtgttag cttgaatagt catcacacct gtcaaactct tcaagtctcc
    12061 cgttcaggtt tctatgctta tttaaaacgt cgtctatctt caaagcatgt tgagaatgaa
    12121 gctttgaagg aaatgattaa agacattttc tatgaacata aagagcgtta cggaagtgta
    12181 cgaattaccc aagaactttg tagacgtggc atccatgtca atcataaacg tgttggtaga
    12241 ctccttcatc agctaggtct ctatgctaaa ggaagtcgat atcaatataa atactataac
    12301 cgtcgacgtt cttcatgaac tcgtcccaat cttgttaatc aatgtttcca agcgactgat
    12361 aagaataaat tatggctagg agacttaacc tacattccta cacaagaagg aatactttat
    12421 gtgtctgtct tg
//
LOCUS       DATWEK010000041        11825 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.041, whole genome shotgun sequence.
ACCESSION   DATWEK010000041 DATWEK010000000
VERSION     DATWEK010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11825
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.041"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(151..888)
                     /locus_tag="VCR92_001534"
     CDS             complement(151..888)
                     /locus_tag="VCR92_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000812013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4268588.1"
                     /translation="MKQLVLKDVCKKYPNQLNYALDHINLIVEKGEFVAVMGRSGSGK
                     TTLLNVTSIIDKIDSGSIYCADKEISAFSDNEATSFRKNDIGFVFQDYMLLDSLTIRE
                     NISVALSLKNVDSSKIDDLINNYAKRFNLYEQLKKYPYQLSGGQRQRVSIIRAIIKEP
                     EIIFADEPTGALDLKSSEGTMRILSEINKIEKVTILMVTHDVLSASYADRVVLLKDGK
                     LHMEIDKEDCGETFYDVISQALSDRGE"
     gene            complement(885..1418)
                     /locus_tag="VCR92_001535"
     CDS             complement(885..1418)
                     /locus_tag="VCR92_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4268589.1"
                     /translation="MDKTDFRNISAFVSQDSPMFDGDVMYNISLGRESVSGEQVIETC
                     KRVSIYDDIRSMPMKFHTPLFRDNPSLSGGQKQRISLARELVTTPRILVLDEPTSALD
                     VKTERIIQKNVEALHCTRILVTHRLNTVEKADKILIMDNGKIIDYGNHHYLYKNNKDY
                     CDLYDSYMNKYQEEEVK"
     gene            complement(1420..3045)
                     /locus_tag="VCR92_001536"
     CDS             complement(1420..3045)
                     /locus_tag="VCR92_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4135 domain-containing protein"
                     /protein_id="HEP4268590.1"
                     /translation="MIKRNELKLEYQQHQFYEYFNSIFDYDILDTSISENIYLLREKT
                     HKLFYSEFENQLFETIMFLSMKTLVLDINHFSKEIENKSEAYEQCIQQIREENGINHF
                     FDRYPYLLKQINKEVGLIEESYSLLFDRFLEDLSEIRSCFNISEPLSNVAFSLGDSHS
                     KKQTVVKIAFKEKSVYYKPKSYHSHSILLELTSLLKSSNIPSFSLPKSLVKADYCWQL
                     GVAYTSSNKDEVAKIYFKYGVLAAFSEIFSITDLHMENVIVSGGDLYLIDVETFFQRK
                     LNVQNQNFEGITVDTYQRIYETSLSNGLFPVQFEKNSAPNVSGISGKGGKRKKGKYEL
                     INKNRGDMKLVKVDYFQEDGFNIPTLNGKVVEPLDYANEIISGFRECYIFLLSQRSKI
                     KGIVEGFPELKSRALFRNTSDYGKFLQASTNPKYLFSEKKKKNLFSILYEAKHIEHFI
                     VDNEIKDLMNGDIPYFSMDTRGNVYNSVGTLIGNLGDTTSLFDSITILNDERLKFTCE
                     LLEIVLKKPIKHWEREKGKSYQFLSISSEHYLL"
     gene            complement(3127..3282)
                     /locus_tag="VCR92_001537"
     CDS             complement(3127..3282)
                     /locus_tag="VCR92_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A2 lantipeptide"
                     /protein_id="HEP4268591.1"
                     /translation="MSFMKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCP
                     NSVFVCC"
     gene            complement(3785..5191)
                     /gene="lacG"
                     /locus_tag="VCR92_001538"
     CDS             complement(3785..5191)
                     /gene="lacG"
                     /locus_tag="VCR92_001538"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEP4268592.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLSEEFGVNGIRISIAWSRIFPTGKGEVNPKGVEYYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSDGDFLNRENIEHFVNYAEFCFKEFSEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLFKDSGYSGEIGVVHAL
                     PTKYPFDANNPDDVRAAELEDIIHNKFILDATYLGKYSDKTMEGVNHILEVNGGELDL
                     REEDFAALDAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     KAPVDVPKTDWDWIIFPQGLYDQIMRVKADYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVISDAISDGANVKGYFMWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAYWYKKVAETQVIE"
     gene            complement(5264..6961)
                     /locus_tag="VCR92_001539"
     CDS             complement(5264..6961)
                     /locus_tag="VCR92_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEP4268593.1"
                     /translation="MNGLIAQIEKGKPFFEKISRNIYLRAIRDGFIAGMQVILFSSIF
                     ILIAYVPNAWGFHWSKDIENLLMTPYNYSMGILGLFVAGTTAKALTDSMNRSLPSTNQ
                     INFISTMLAAIVGFLLMAANPAKDGGFLTGFMGTKGLLTAFIAAFITVNVYKTCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTLSVVLLYVIELIVHTTLGVNVAESIGKLLAPLFQ
                     AADGYVGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAETNLQLLQAGEHADKIL
                     TSGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNKAIGRASVVPTFFGVNEPILFGAPL
                     VLNPIFFIPFILAPIVNVWIFKFFIDTLGMNSFTANLPWTTPAPLGLILGTNFQVLAF
                     ILAALLIVVDVIIYYPFLKVYDEQILAEEAAGTNSSDALKEKVAANFDTKKADAILEK
                     SAAKETKEITDQTNVLVLCAGGGTSGLLANALNKAAKEYGAPVTAAAGSYGAHREILP
                     QYQLVILAPQVASNYEDMKVETDKLDIKLAKTEGAQYIKLTRDGQGALDFVKEQMEK"
     gene            complement(6961..7278)
                     /locus_tag="VCR92_001540"
     CDS             complement(6961..7278)
                     /locus_tag="VCR92_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEP4268594.1"
                     /translation="MNREETTLLGFEIVAYAGDARSKFLEALKAAQEGDYAKAEELIA
                     AGSDCLNDAHNAQTSLLQKEAAGDDLAYSVTLMHGQDHLMTTILLQDLMKHMIELYKR
                     GAK"
     gene            complement(7302..8285)
                     /gene="lacD"
                     /locus_tag="VCR92_001541"
     CDS             complement(7302..8285)
                     /gene="lacD"
                     /locus_tag="VCR92_001541"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEP4268595.1"
                     /translation="MTITLTENKRKSMEKLSIDGVISALAFDQRGALKRMMAQHQTKE
                     PTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTT
                     SRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIP
                     FYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSEERFGVDVLKVEVPVNMKFVES
                     FADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVL
                     CGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM"
     gene            complement(8288..9217)
                     /locus_tag="VCR92_001542"
     CDS             complement(8288..9217)
                     /locus_tag="VCR92_001542"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEP4268596.1"
                     /translation="MILTVTLNPAIDVSYPLNELKCDTVNRVVDVTKTPGGKGLNVSR
                     VLNDFGETVKATGCIGGESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEIL
                     EKGPLLSVDEIDGFTHHFKYLLNDVDVVTLSGSLPAGMPDDYYQKLIKIANLNGKKTV
                     LDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTKDFEALKEVLQDELFEGIEWI
                     IVSLGADGVFAKHKDTFYNVDIPKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKA
                     NVLGMLNAQEKTTGHVNMANYDKLYQSIKVKEV"
     gene            complement(9263..9778)
                     /gene="lacB"
                     /locus_tag="VCR92_001543"
     CDS             complement(9263..9778)
                     /gene="lacB"
                     /locus_tag="VCR92_001543"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEP4268597.1"
                     /translation="MKIAVGCDHIVTYEKIAVVDYLKSQGHEIIDCGTYDNVRTHYPI
                     FGKKVGEAVASGEAELGVVICGTGVGITNAVNKVPGIRAALVRDMTSAIYSKEELNAN
                     VIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNPHFFDEF
                     LEKWDRGEYHD"
     gene            complement(9813..10241)
                     /gene="lacA"
                     /locus_tag="VCR92_001544"
     CDS             complement(9813..10241)
                     /gene="lacA"
                     /locus_tag="VCR92_001544"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEP4268598.1"
                     /translation="MAIIIGADKAGQELKEVIKDYLKEGKYEVVDVSENEVRDFVDTT
                     LAVAKEVNASEDNLGIVIDAYGVGSFMVATKIKGMVAAEVSDERSAYMTRGHNNARII
                     TLGSEISAPGIAKNIIKGFVEGKYDGGRHQVRVDMLNKMC"
     gene            10687..11460
                     /locus_tag="VCR92_001545"
     CDS             10687..11460
                     /locus_tag="VCR92_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004270277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEP4268599.1"
                     /translation="MKKKERHEKILDILKVDGFIKVKDIIDEMNISDMTARRDLDTLA
                     DKGLLIRTHGGAQYLDYSSAKDEGHEKTHTEKKVLQTTEKKQIAQRAKNIIKDGETVF
                     IGPGTTLEHLAVELKNRNIRVITNSLPVFLILHPSTTIDLILIGGECREITGAFVGAI
                     AINNLESLTFSKAFVSANAVYNNSIATYSDLEGEVQRVALNNAVEKILLVDSTKFESY
                     DFYNFYQLDQVDLIVTDKNVTTDIIEKYKKFSKIIIADK"
BASE COUNT         3726 a         2276 c         1818 g         4005 t
ORIGIN      
        1 ctatccccaa ttttttctgt aatgatttta tctgagataa aatttagaaa agctataaaa
       61 atacttaata aaccaatcgt agctagaaaa tagatacgat ataacgaaaa gttttttttg
      121 atgttagatt ttgtaatgga ccaaatcata ttactctcct ctatcggata aggcttgact
      181 aattacatca taaaacgtct ctccacaatc ctctttatca atctccatgt gaagtttacc
      241 atctttgaga agtacaactc tatccgcata agaagctgat aaaacgtcat gagtaaccat
      301 taaaatagtt accttttcta ttttattgat ttcactcaaa atcctcattg ttccttcaga
      361 agattttaag tcaagcgctc cagttggttc gtcagcaaaa ataatctctg gttctttaat
      421 gattgctctg ataatactga ccctctgtct ttgacctcca gaaagttgat acggatattt
      481 tttcaactgc tcatataaat taaatctttt tgcatagtta tttatcaaat catcaatttt
      541 tgatgaatca acatttttta aagatagagc aacagaaata ttctccctaa tggttagact
      601 gtctaacagc atataatctt gaaaaacaaa accaatatca ttttttctaa aactagttgc
      661 ctcgttatca gaaaatgcac taatttcttt gtctgcacaa taaatactcc cactatcaat
      721 tttatcaata attgaagtaa catttaaaag tgttgttttt ccactaccac tacgccccat
      781 gacagctaca aattctcctt tttccacaat caaattgata tggtctagag cataattcag
      841 ttgattggga tattttttgc aaacatcttt taatactaat tgtttcattt tacctcttcc
      901 tcctgatatt tattcatata cgagtcatat aagtcacaat aatccttatt atttttgtac
      961 aaataatgat ggtttccata gtcaataatt ttgccattat ccattattaa aatcttatca
     1021 gctttttcaa ctgtattaag tctatgggta accaaaatcc tcgtacaatg taaagcctca
     1081 acattttttt ggattattct ttcagttttt acatctaaag ctgatgtagg ttcgtcaaga
     1141 actaagattc taggggtggt tacaagttct cttgctaaag aaattcgttg tttttgcccc
     1201 ccagatagtg atggattatc tcgaaaaagt ggggtatgaa acttcattgg catactcctg
     1261 atatcatcat atattgatac ccttttacaa gtttcaataa cctgttctcc tgaaacagat
     1321 tctctcccta gcgaaatgtt atacatcaca tccccatcaa acatgggaga atcttgagat
     1381 acaaaagccg atatattcct aaaatcagtt ttatcaattt tagagaaggt aatgttctga
     1441 ggagattgat aaaaactgat aagatttgcc cttttccctc tcccaatgct taatcggttt
     1501 tttcaagact atttcaagca attcacaagt gaacttcaat ctttcatcgt tcaaaatagt
     1561 tatactatca aataacgagg ttgtatctcc tagatttcca attaatgtcc ctacagaatt
     1621 atagacgttt cctctggtat ccattgaaaa gtaaggaata tcaccattca tcaaatcttt
     1681 aatttcatta tcaacaataa aatgttcaat atgttttgcc tcatatagta tcgaaaataa
     1741 attcttcttc tttttttctg agaaaagata ctttggattc gtagaagctt gcaaaaattt
     1801 tccataatcg gaagtatttc gaaatagggc tctgcttttc aattctggaa aaccttctac
     1861 tattccttta atctttgaac gttgtgatag aagaaatatg tagcactctc taaatcctga
     1921 aatgatctca ttagcatagt caagaggctc taccactttc ccatttaatg tgggaatatt
     1981 gaacccatct tcttgaaaat agtcaacttt tactaacttc atatctccac gatttttatt
     2041 tatcagttca tattttcctt tttttctttt tccacctttt ccacttattc cagaaacgtt
     2101 aggagcgctg tttttctcaa attgtacagg aaataaaccg tttgaaagtg atgtctcata
     2161 aattctctga taggtgtcta cagtaatccc ttcaaaattc tgattttgta cattcaactt
     2221 tctttgaaaa aatgtttcaa cgtcaattaa atataaatct ccgcctgaaa caatcacatt
     2281 ttccatatgt aagtccgtaa tagaaaatat ttcagaaaat gctgctaaaa caccatactt
     2341 aaagtaaatt ttcgctactt catctttatt ggaacttgta taagctacac caagttgcca
     2401 acaataatct gctttaacta agcttttagg aagactgaat gaaggtatat tactagattt
     2461 caataaacta gtaagttcta acaagatact gtgtgaatga taacttttag gcttgtagta
     2521 aacagatttc tctttaaacg caattttaac aactgtttgc tttttagagt gactgtcacc
     2581 aagtgaaaag gcaacattgc ttaggggctc actaatgtta aagcacgacc ttatctcaga
     2641 taagtcttct aaaaatctat caaataataa agaatatgat tcctctatca gtcctacttc
     2701 tttattaatt tgttttagca aatacggata cctgtcaaaa aaatgattta ttccgttttc
     2761 ttctcttatc tgctgtatac actgctcata tgcctctgac ttattttcaa tttccttgga
     2821 aaaatgattt atatctaaaa ctagtgtttt catcgaaagg aacatgatcg tttcaaataa
     2881 ctgattttca aactcactat aaaataactt atgtgtcttt tcccttaaca aataaatatt
     2941 ttcactaata gaagtatcta atatgtcgta atcaaaaatt gagttaaagt attcgtaaaa
     3001 ctgatgttgc tgatattcta actttaattc atttcttttt atcatttttt cctaccacta
     3061 cttaaaaatc ctgcctagac taagtctaaa caggaaattt tagtctgctt atccagattg
     3121 ttttaattaa caacaaacga atactgagtt cggacagtca tcagtaatag ttgcaaacca
     3181 accggaacct tttttaccac cagctacttc cataagttct ttttcagaaa cttcttcgat
     3241 agcattagtc aaaatatcct ttgaattttt cataaaactc attctccttt ctatcagtat
     3301 gtagtgacta ttttctacac ttttattgta aataatacgt cttcattttc aatgagtaaa
     3361 aagtgcaaaa atgacttttt tcatattttt tagtaagatt tttgagatgt cacataagag
     3421 gtcactttat aacaaatagc cctctgatat aaaaaacaaa actcgttctt tacagctatt
     3481 ttacaatcta atcgcttctt gttataacat caatctctaa tcagaaaatg gttactttac
     3541 ttatttaatc aggtcaggag tttgaatgac agaagtcaaa tatctgaaaa aggatattaa
     3601 ataaaacttt caaaacccat tttcatcaac taaaaacact tataacccga tcttacaact
     3661 aatggattac catcaacagc aaataatact atgcttgaaa aatgtcaaca tcatctactt
     3721 tttgtgacta taattcagta aacgaacatg aagtgtaaaa atgtattaaa aaagtatctc
     3781 aaaatcattc aatcacttga gtttctgcta cttttttata ccagtaggca ctcttcttag
     3841 gataacgttc ttgagtttca aaatcgacat agaagagacc gtaacgtttt tcatagccat
     3901 ttgaccatga aaagacatcc atcagtgacc acataaagta tcctttaaca tttgcaccat
     3961 cagaaatagc atcagaaata acttctaagt gttttttcac ataatcgata cgtccatcat
     4021 catagacagt attatctaca aactcatctt tgtagccaag accattctct gtaatgtaaa
     4081 ttttcttgta gttaggataa tcggctttga cacgcatgat ttgatcatat aagccttgtg
     4141 ggaagataat ccagtcccag tccgtttttg gaacatcaac gggtgctttt cttcgaccaa
     4201 cacccttgat ttggtattta gagctgcctt tttccccttt accattatga atgatttcag
     4261 tctcaccatc aaaagcttgc atccaatcac tcatataata gttaatacca aggaagtcat
     4321 tcaaatcttt tgcagcgtct agtgcagcaa aatcttcctc acgaagatca agttcaccac
     4381 catttacctc aaggatatgg ttaacacctt ccattgtttt atctgaatac ttacctagat
     4441 aagttgcatc aagaataaat ttattatgga tgatatcttc cagttcagct gctctaacat
     4501 catcaggatt gttagcgtca aatggatact tagttggaag agcatggacc acgccgattt
     4561 cacctgaata gccactatct ttaaagagtt tgactgcacg agcatgagag accatcatgt
     4621 tatggtgtga ttggaaaact ttagcaagat catattggat acctggaggg aatttaccaa
     4681 ccaagtattg gccatcacca ataggcccaa tttcgttaaa tgttgtccaa tagttaactt
     4741 ctgagaattc tttaaaacaa aattctgcat aatttacaaa atgttcaatg ttctcacgat
     4801 tgaggaaatc accatccgag tggagagctt ctggggtatc aaaatggtga agtgtaacaa
     4861 aaggctcaac atgacgctta tgacactctg caaagagatt gtggtagtat tcaactcctt
     4921 tagggttaac ttctcctttt cctgttggaa aaatacgaga ccaggcaata gagatacgga
     4981 tgccgttgac accaaattct tcactaagtt tcaaatcgac tggataacga ttgtaaaaat
     5041 cacttgctgg ctcagctgtg taccaatagt tgtcttctaa gtatttatcc caagctactg
     5101 gtcctttacc atctgtgtgg gtagcgcctt cagcctggta agcagctgta gcaccaccaa
     5161 aaataaaatc tttaggtaat gttttagtca tgatatacct cttctaaatt ttcatttcac
     5221 tataaaggaa gattgagtac ccccaacctt ccctagcgac atattatttt tccatttgtt
     5281 ctttaacgaa gtctaatgcg ccttgaccat cgcgagtcaa tttgatgtat tgagcccctt
     5341 ctgttttagc taatttaata tcaagtttat cagtttccac tttcatatct tcatagttag
     5401 aagctacttg aggtgcaagg ataacaagtt gatattgtgg taaaatctca cggtgagcac
     5461 cataacttcc tgctgctgca gtgacaggtg caccatattc tttagctgct ttattcaaag
     5521 cgtttgcaag caaaccactt gtaccaccac cggcacaaag aacgagaaca ttagtttgat
     5581 cagtgatttc tttggtttct ttagctgctg atttttcaag aatagcatca gcttttttag
     5641 tatcaaagtt tgctgctact ttttctttga gggcatctga tgaattcgta cctgctgctt
     5701 cttcagcaag aatttgctca tcatatactt ttaagaatgg gtagtagata atcacatcaa
     5761 caacaattaa caaagctgcc aaaatgaatg ctagcacttg gaagtttgtc ccaaggataa
     5821 gacccaatgg agctggtgtt gtccaaggta agtttgcagt gaaactgttc attccaagtg
     5881 tgtcaatgaa gaatttgaaa atccatacgt tgacaatcgg tgccaggata aatggaataa
     5941 agaagattgg gttcaaaaca agtggggcac caaacaaaat gggttcgtta acaccaaaga
     6001 atgttggaac aactgatgca cgtccaatgg ctttgttacg ttttgatttt gttaaccaca
     6061 tgaacatgaa tggaacgacg agagttgcac cagtaccacc catggtaacg atgaacattt
     6121 gagtccctga agtcaagatc ttatcagcat gttcaccagc ttgaagtaat tgaaggttgg
     6181 tttcagcatt tgcgtaagta atcgctgcaa tggctggttc aacaatagat ggtccatgaa
     6241 taccaacaaa ccagaagaaa gcaaatgcac cgaagataat agtgattcca acatagccat
     6301 ctgctgcttg gaacaatggt gcaagaagtt taccaattga ttctgcaacg ttaacgccta
     6361 aagtagtatg aacaatcaat tcaatcacat aaagcagtac aactgataac gtaaatggaa
     6421 tcaaatcttt aaaaacttga gatatatttg gtggaacctc ttctggcatg cgaatagtaa
     6481 cattgttttt cacacaggtt ttatagacat ttacggtaat aaaagctgcg atgaaggctg
     6541 tcaacaaacc ttttgttccc ataaatccag ttaagaaacc accgtctttt gctggattgg
     6601 ctgccataag taaaaaacct acaatagcag cgagcatagt tgaaataaag ttgatttggt
     6661 ttgtgcttgg taatgatcga ttcattgagt cagttaaagc tttggctgtc gtaccagcca
     6721 caaacaaacc taaaataccc attgagtagt tgtatggcgt catcaagaga ttctcaatat
     6781 ccttactcca atggaagccc catgcatttg gaacataggc aatcaagata aagatacttg
     6841 aaaacaagat aacttgcata ccagcgataa aaccatcacg aatagcgcga agatagatat
     6901 ttcgagaaat tttctcgaag aaaggtttcc ctttctcaat ctgagcaatt aatccattca
     6961 ttattttgct cctctcttat aaagttcaat catgtgtttc attaaatctt gtaataaaat
     7021 ggtcgtcatt aaatgatctt gaccatgcat taaagtgaca ctataagcta agtcatctcc
     7081 agctgcttct ttttgtagta gacttgtctg agcattgtga gcatcattca agcagtcact
     7141 acctgcagcg attaattctt ctgctttagc ataatctcct tcttgcgctg ctttaagcgc
     7201 ttccaaaaat tttgaacggg catcaccagc ataggctacg atttcaaaac ctaaaagagt
     7261 agtttcttct ctattcattg tagtttcctc cgaaaataat gttacatttt ttcagtccaa
     7321 ggacttgcag ttttatctag tactttgttt aattcgtcaa tatttttgaa accttctgta
     7381 cgcaaccatt cacgagctgc ttgtggtcct tcttcgatat agacttttac agatcctgcc
     7441 caggtagcac gtccacataa gacaccgttg aatttagcac ctgattctgc tgcaaacacc
     7501 aaagtatctt ggaacaattt ggcagaaaca cctgcactca agtaaatata tggtaaatca
     7561 gtagaagctt cttggtcacg gaaagcttga gctgcttctt cttttgtaaa gagaacctca
     7621 ccatctgcaa agctttctac aaatttcata tttactggaa cttcgacttt caagacgtca
     7681 acaccaaagc gttcttctga gaagactttc attgcttcat taactttatg agctttaact
     7741 tttgcaaact cagggcttgc attgtcagca attttctcat cataagttag aatttctaag
     7801 tagaatggaa tatcttctgc acggcattca gaaccaatac gttcaatgta agcttttttc
     7861 tgctcgttaa catcttgatc tccatcaata tcatagtaaa gaaggaattt aactgcttct
     7921 gctccagctt ctttaatacg ttttgcagac caaacatcta agcaatcagg taagcgacta
     7981 gttgttgttg catcgtatcc tgttttctca tatgccaaca acaagcctgc ttcttctgaa
     8041 cgaacacgac ttgctggcaa gccatattca ggatcaagta aaattgatga tgcaaatggt
     8101 gtcagttctt cagaaactaa acttttaagc tcttcaattt gttctactgt tggctctttt
     8161 gtttgatgtt gagccatcat acgtttgaga gctccacgtt ggtcaaaagc taaagcagaa
     8221 ataacaccat ctatacttag tttttccatg cttttacgtt tgttttcagt taaagtaatt
     8281 gtcattttta tacctctttg actttaatag attgatataa cttatcgtaa tttgccatgt
     8341 taacatgccc agttgttttt tcttgcgcat ttaacatacc taagacattt gcttttgtta
     8401 ataaagctcg atcatcttca tcattcgcta aacctgaagc aatacctgcc actgtagaat
     8461 cacccgaacc tacagcgctt acaattttga ttttaggaat gtcaacgtta taaaacgtat
     8521 ccttgtgctt tgcaaataca ccatcagcac caagagaaac gattatccat tcaattcctt
     8581 caaatagttc atcttgtaag acttctttta aggcttcaaa atcttttgtc atttctttac
     8641 ctagaagttg agaaagttct tcaagattag gtttgataac tgttggttta ctatcacctt
     8701 tcaatactgc ttctaaagca tttccagaac aatccagaac agtcttctta ccattaagat
     8761 tggcaatctt gattaacttc tgatagtaat catctggcat accagcaggc aaactgcctg
     8821 agagcgtcac tacgtcaaca tcattcagta aatatttaaa atgatgagta aatccatcaa
     8881 tttcatctac acttaacagc ggtccttttt ctaaaatctc agtttgatta ccttcgtgta
     8941 atatggctat acatgttctg gtatcacctg aaattttata gaagcgactt aaaatcgaat
     9001 caggaagatg attaatgata aaatcaccgc tttctccacc aatacaacca gtagctttga
     9061 ctgtctcacc aaagtcattt agaactcggg aaacattcaa gcctttacca ccgggtgtct
     9121 ttgtaacgtc tacaactcga ttgacagtat cgcattttag ctcattcaaa gggtaggaga
     9181 cgtcaatagc tggatttaaa gtaactgtta aaatcacaat agctcctttt tctatatatc
     9241 cttatcataa ttctttcaaa tattagtcgt gatattcacc acggtcccat ttttctagaa
     9301 attcatcaaa gaagtgtggg ttgttttgat cttggctagc atgttgcaag ctatccattt
     9361 tttcaatcca ttttttattt tcttcagttg gtttgtattc agccgctaag aaagcatcga
     9421 taatatcatt catcagcaaa ccaccgatga tttttccacc aaaaccaata acgtttgcgt
     9481 ttagctcttc ttttgagtag atagcagatg tcatatctct aacgagtgct gcacgaatac
     9541 cgggaacttt gtttacagca tttgtgatac caacaccagt accacagata acaacaccta
     9601 attctgcttc accacttgct actgcttcac caactttttt accaaagatt ggatagtgtg
     9661 tgcgaacatt atcgtatgta ccgcaatcaa tgatttcatg accttgtgat tttaggtaat
     9721 ccacaacagc gattttttca taagtaacaa tatggtcaca acctacagca attttcattt
     9781 ttgttctcct tgttttaacc tatttcaatc aattagcaca ttttattaag catgtcgaca
     9841 cgaacttgat gacgtccacc atcatattta ccttcgacaa agcctttgat aatgttcttt
     9901 gcaattcctg gagcactaat ttcagaacca agcgtgatga ttcgagcatt gttgtgtcct
     9961 cttgtcatgt atgctgaacg ctcatctgat acttcagctg ccaccattcc tttgatttta
    10021 gtagctacca tgaaagaacc aacaccatat gcatcaatga caatacctaa gttatcttcg
    10081 gaggcattaa cttcttttgc aacggctaaa gttgtatcta caaagtcacg tacttcgttt
    10141 tcactaacat caacgacttc gtatttacct tctttaaggt aatctttgat aacttcttta
    10201 agttcttgac ctgctttgtc agcaccgata ataattgcca ttttatttct cctatgattt
    10261 agaataagta aatgtggaaa acctacgtag atagttaatt aacgatttgc aacatctttt
    10321 gaaataacgc tttcattatt tctatgacct aatcatacac ccaccaaaca taaaagtcaa
    10381 catttttttg tttattttta taaaaaataa acaaaatatg tttatttttt tcatttttac
    10441 gttattatcc taatgtttct tgtgtttctt tttcatttca taaatccctt tgacagccac
    10501 tcgtaaccta tcatatatta cgagaccctt atctctattt attgtaaacg ttttatttaa
    10561 aacattttct attttgttaa tttttgtttt ttccaatgtt tatgtttgtt ttgtttgatt
    10621 tttttattga tattatgtta tgataccttt aatagttata ccctaagaca ctgataggag
    10681 ataagaatga aaaagaaaga gcgtcatgaa aaaattctcg atatcttaaa agttgacggt
    10741 tttataaaag taaaagatat tattgatgaa atgaacatct cagatatgac cgctagacga
    10801 gatctcgata cattggcaga taaaggatta cttatcagga cccatggtgg tgctcaatat
    10861 ttggattatt cttcagcaaa ggacgaaggt cacgagaaaa cacacactga aaagaaggtc
    10921 ttacagacta ccgaaaaaaa acaaattgca caaagagcta aaaacattat taaagacggc
    10981 gaaactgtct ttataggtcc agggacaaca ttagagcatc tagctgtcga attaaaaaat
    11041 agaaatatca gggtcattac aaatagcctt cctgtttttt taattttgca cccgagcact
    11101 actattgatt tgattttaat tggtggtgaa tgtcgtgaaa ttactggagc ttttgttggt
    11161 gctattgcca ttaataatct agaatcatta actttttcaa aggcttttgt tagcgcaaat
    11221 gcagtttaca ataattctat tgcgacgtac agtgatctcg aaggagaagt tcaaagggtt
    11281 gcattgaata atgctgttga gaaaatcctt ctagttgata gtaccaagtt tgaaagttat
    11341 gacttctata atttttacca actagatcaa gtggacttaa ttgtgactga taaaaatgtg
    11401 acaactgata tcatagaaaa gtacaagaaa ttctcaaaaa tcataatcgc tgacaagtaa
    11461 aggacctact catattaaaa agcacttcag ggtttagata tatcccctgt caagtaaaca
    11521 gggagcatat ctgaaagtag tgtttgtgtt ataaagaagt ttcttgctaa cttattttct
    11581 ggtttttttc agacttatca gtcttgtact gttccttttt ctgatgaata acgtggaaat
    11641 aggcagacag ctatatattt cacctctaga atggttgtca ttactgtcat caagacatgc
    11701 ttgttcttta tcgtatggag tgaagctttc ttttagacat caacatacct cttaagtaga
    11761 ttttggttcg ttaccatgtc tacttaagag gtgtcttcaa agcgctttaa aacgttgata
    11821 taaca
//
LOCUS       DATWEK010000042        11616 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.042, whole genome shotgun sequence.
ACCESSION   DATWEK010000042 DATWEK010000000
VERSION     DATWEK010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11616
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.042"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            1..1056
                     /locus_tag="VCR92_001546"
                     /pseudo
     CDS             1..1056
                     /locus_tag="VCR92_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1105..1836)
                     /locus_tag="VCR92_001547"
     CDS             complement(1105..1836)
                     /locus_tag="VCR92_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEP4268600.1"
                     /translation="MRLDKFLVATGVGTRSQVKLLLKKKAIFVNQKVETSAKAHIDEY
                     KDLVTYQGTPLVYESFVYYLLNKPSGYVSATQDRQQATVMELLDDTARQKAVFPVGRL
                     DKDTRGLLLLTNNGQLAHDLLSPKKHVTKEYLAKVVGIMTEADKDYFARGISLKDHQC
                     LPAHLEVLASDLQQRTSLVKITIQEGKFHQVKRMVAACGKGVLDLQRLSMGPLKLDPS
                     LAEGEFRRLTPEELQSLAPYCQSSL"
     gene            1951..2316
                     /locus_tag="VCR92_001548"
     CDS             1951..2316
                     /locus_tag="VCR92_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEP4268601.1"
                     /translation="MTIYSHTYETRPNHSAKAMGSGTLNVLATPALVAFMENASYLFA
                     QEQLDSDFTTVGSEIAIQHLAASAIGDPVTIIITALKEEGRKYDFRLEAFVGEQLIGK
                     ACHTRVRVNSKHFMAKVAE"
     gene            complement(2436..3656)
                     /locus_tag="VCR92_001549"
     CDS             complement(2436..3656)
                     /locus_tag="VCR92_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP4268602.1"
                     /translation="MSTLSLDTTNKRALVAAIAASGTDDLNVMFLAFSMSSIMTDLSL
                     SGTQGGWIATITNLGMLVGGLLFGLLADRHHKFKVFKWTILLFSVATGLIYFTQSLPY
                     LYLMRFIAGIGVGGEYGVAIAIMAGIVPPEKMGRMSSLNGIAGQLGSISSALLAGWLA
                     PSLGWRGLFLFGLLPILLVIWMTLAIDDQKIWDHYGQEEEECSQPIKINELFKTKSLT
                     AQTLALMVMTTVQIAGYFGMMNWLPTIIQTSLNLSVKSSSLWMVATIVGMCLGMLCFG
                     QLLDCFGPRLIYSLFLLASSICVYLFQFANSMASMVIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNVILNVGRALGGFSSVAIGSILDASGISMVMIFLASLYVISFGAMW
                     SIGQLKAERYQQLR"
     gene            4030..5514
                     /locus_tag="VCR92_001550"
     CDS             4030..5514
                     /locus_tag="VCR92_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEP4268603.1"
                     /translation="MKTIAFDSNKYLNLQRDHILERISQFDGKLYMEFGGKMLEDYHA
                     ARVLPGYEPDNKIKLLKELKEQVEIVIAINANNIEHSKARGDLGISYDQEVFRLIDKF
                     NTLDIYVGSVVITQYNNQPAADAFRKQLKKNGIASYLHYPIKSYPTDINHIISSEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCISQMYHDQINGVKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTESAVKKIELLMND
                     IGVTPDDRHVTVAAHQKAEQTGQPALALQLPNGQIVTGKTSELFGPTAAVIINAIKTL
                     AKIDKTTHLIEPEYVKPIQGLKVNHLGSHNPRLHSNEILIALAITAMTSEEANLAMKE
                     LGNLKGSEAHSTVILTEEDKNVLRKLGVNITFDPVYQHHKLYRK"
     gene            complement(5619..6020)
                     /locus_tag="VCR92_001551"
     CDS             complement(5619..6020)
                     /locus_tag="VCR92_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEP4268604.1"
                     /translation="MSDLTQEMTLNVISIFDNYQIELAEKGHLILSTEVTETALNYYG
                     NAHGGYLFTLCDQVGGLVARTTGVESVTLQANANYLKAGHKGDKLMVEGRLVHGGRTT
                     QVVDVTIHNQTGALLTKTSLTMFVTGRRHNG"
     gene            complement(6105..6886)
                     /locus_tag="VCR92_001552"
                     /pseudo
     CDS             complement(6105..6886)
                     /locus_tag="VCR92_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060407.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
     gene            complement(7038..8717)
                     /locus_tag="VCR92_001553"
     CDS             complement(7038..8717)
                     /locus_tag="VCR92_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEP4268605.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRKQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGLSKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGAGMFGNKCTKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFRKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKIIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLITAL
                     ISEIQVYEEKQPNGQWLKSITFKLPIIDDDLNISLDNNEQVECVSLLEKRS"
     gene            complement(8814..8975)
                     /locus_tag="VCR92_001554"
     CDS             complement(8814..8975)
                     /locus_tag="VCR92_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268606.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     KAKTQIETD"
     gene            complement(9673..10401)
                     /locus_tag="VCR92_001555"
     CDS             complement(9673..10401)
                     /locus_tag="VCR92_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEP4268607.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKS
                     TPIFYGEFKNVRLSKEEYKNLKEKLNSHTEIMINKLSRYMESSGKTYQNHYATILNWY
                     DKDKDKLRQKSLNKKMNYDVGESL"
     gene            complement(10527..11054)
                     /locus_tag="VCR92_001556"
     CDS             complement(10527..11054)
                     /locus_tag="VCR92_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEP4268608.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKAAKESINLEKEIRKKMNDTLE
                     KANGNLKSLMGDEIKIKDLYKKGQLENISIDQSNLKDLKKELNKLGVSFSVMKNKESQ
                     NYEVFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKNKTKEKVKRKV
                     KEKVKPNKKDMTREI"
     gene            complement(11238..11411)
                     /locus_tag="VCR92_001557"
     CDS             complement(11238..11411)
                     /locus_tag="VCR92_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004829396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268609.1"
                     /translation="MNKRQELIDELIKADQDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHTNC"
BASE COUNT         3313 a         2386 c         1933 g         3984 t
ORIGIN      
        1 agcgcaatac aagaaaaacg gttatactat tcttgaaaaa ccaagaggga gaccgagtaa
       61 gatggggcgt aaacgtaaga aaaatttgga agagatgaca gaggttgaac gtcttcagaa
      121 ggaattagaa taccttagag cggagaatgc tgtgctaaaa aagctgagag aataccgctt
      181 gagggacgaa gtaaagctca aagagcaaca gaaatcattc aagcattaag gaatcaattt
      241 cccttagaga tgctacttga gatccttgat ttatcacgct ccacctatta ctatcaagtg
      301 aagcgactag ctcaaggaga taaggatata gaactaaagc atgtgattcg agagatttat
      361 gatgagcata aaggtaatta cggttatcgt cgtattcata tggagttgcg taaccgagga
      421 tttgtggtca atcataagaa ggttcaacgt ctcatgaaag tcatgagcct agcagcccgc
      481 attcgtcgga agcgcaagta ttcttcttac aaaggagagg ttggtaagaa ggctgataat
      541 ctgattaaac gtcacttcga aggctctaaa ccttacgaaa aatgttacac tgatgtgacg
      601 gagttggcct tacctgaagg aaaactctac ttattacctg ttcttgacgg ctataacagt
      661 gagattattg atttcactct gtctcggtct cctaacttga aacaggttca aaccatgctt
      721 gagaagactt ttccagcgga ttcatacagc ggaactattc ttcatagtga ccaggggtgg
      781 caataccaac accagtccta ccatgatttt ttagagtcta aaggtatttt gccatccacg
      841 tcccgcaaag ggaatagccc ggataacggc atgatggatt ccttctttgg cattctcaaa
      901 tctgaaatgt tttatggact cgagacaact tatcaatcac ttgataagct tgaagaagct
      961 attacagatt acattttttg ctacaacaac aaacgaatta aagcaaaact aaaaggattt
     1021 agtcctgtcc aatacagaac taaatccttt caataattat ttgtccaact ttttggggtc
     1081 agtactgaca ggggaggttt ctttttatag tgagctctga caataaggtg ccaggctttg
     1141 caattcctca ggcgtcaggc gcctaaactc cccttctgca aggctagggt ctagttttaa
     1201 tggtcccatg ctgagacgct gcaagtcaag cactcccttt ccacaggctg ctaccatgcg
     1261 tttcacctga tggaattttc cttcttgtat ggtaatttta accaaacttg ttcgctgctg
     1321 taaatcacta gcaagcactt ctaaatgagc aggtaggcac tggtgatcct ttaaggaaat
     1381 acctctagca aaataatctt tatcagcttc agtcatgatg cctactactt tagccaagta
     1441 ctctttcgta acatgttttt taggggataa aaggtcatgg gctagttgtc cattattggt
     1501 caagagcaaa agtccacggg tatccttatc taacctaccc acaggaaaaa ctgctttttg
     1561 cctagccgtg tcatctaaca actccataac agtagcctgc tgtctgtcct gggttgctga
     1621 cacataccct gacggcttgt ttaacaggta ataaacaaag gattcataga ccaagggcgt
     1681 gccttgatac gtcaccaaat ccttgtattc atcaatgtgt gctttggcag aggtttcaac
     1741 cttttgattg acgaaaatag ccttcttttt taagagaagt ttgacttggc tcctagttcc
     1801 aacaccagtt gccactaaaa atttatctaa gcgcatcata accctttcaa agaaaattca
     1861 ttattaagta taacataaaa aaacagtagt ttcatgactg taagcgctta atatattata
     1921 ataggcttat agaaacgagg agattaactt atgactattt attctcacac ttatgaaacc
     1981 cgtcccaatc attcggctaa agccatgggc tcaggaacgc tgaatgtcct agctactcct
     2041 gctcttgttg cttttatgga aaatgcttct tacttatttg cccaagaaca gctcgacagt
     2101 gactttacaa cggttggcag cgagatagct atccaacatt tggcagcttc agccattgga
     2161 gatcctgtta caatcatcat tacagccctt aaagaagaag gccgaaaata cgatttccgc
     2221 ttggaagctt ttgtgggaga acaactcatt ggaaaagcct gtcatactag agttagggtg
     2281 aacagtaaac attttatggc caaagtagcg gagtaaaaca aaagaaaaga accaaaaagg
     2341 taagcaatcc ctaagtgctt acctttttgg ttatctcaat caataaaata gctttgtgag
     2401 tgaaagtaac tcaaatacta acacccatct ctttgctaac gcaattgttg gtagcgttct
     2461 gcttttaact gaccaataga ccacatagct ccaaaactaa tcacatacag agaagctagg
     2521 aaaatcatga ccattgaaat acctgaggca tctaaaatac taccaatagc aacggacgaa
     2581 aatcctccta gagcacggcc aacattcaaa ataacattat tagccgtgga tcgaatgtga
     2641 tggggataaa gtctggtaat catagccccg tagccagcaa acatcccatt gacaaaaaaa
     2701 ccgacaatag cacctccaat aaccatactc gccatggaat tggcaaattg aaaaaggtaa
     2761 acacaaatag atgatgctaa taaaaagagg gaataaatca gacgtggacc aaagcaatct
     2821 aaaagctgac caaaacacag catccccaaa cacatgccga caatagtagc caccatccac
     2881 aaggacgaac tttttactga aaggtttaag cttgtttgaa taatggttgg caaccaattc
     2941 atcattccaa aatagcccgc aatctgcaca gtcgtcatta ccattaaagc aagggtttga
     3001 gctgttaagg attttgtttt gaatagttca ttgattttaa ttggttgact gcattcttcc
     3061 tcctcttgcc cataatgatc ccaaattttt tggtcatcta tggctaaagt catccaaatc
     3121 accaagagaa tcggaagtaa tccaaagaga aaaaggccac gccagcctag acttggagcc
     3181 agccaccctg ctaaaagagc cgaactaatg gagccaagct ggccagcaat accatttaaa
     3241 gaagacatcc gacccatttt ttctggtggt acaatccctg ccattatggc aatggctaca
     3301 ccgtactcac ctccaactcc tatgccagca ataaatcgca tcaggtacag gtagggcaaa
     3361 gactgggtaa aataaattaa tcctgttgct actgaaaaca gtaaaatcgt ccatttaaag
     3421 accttaaact tgtggtgcct atcagccagc aacccgaata agaggcctcc caccaacatt
     3481 cctaaattgg taatggtcgc aatccagcca ccctgagtgc cactaagact caagtctgtc
     3541 ataatggaag acatggaaaa ggcaagaaac atgacattca agtcatccgt tcctgaagct
     3601 gcaatagctg ccactaaagc tcgcttattt gtggtgtcca atgataatgt tgacataatt
     3661 gtctccttct taatagtagc tcactgacta ccttaattaa ttgaataccc tttgtccaaa
     3721 ggtcaaaaaa agacttggaa acaagtccgc aagtccatca aagttcacta aacaataaga
     3781 gatgacaaaa aaactctctt taatgttaag actttcatgc ttcacggaac atgtttaaag
     3841 tagtatttaa ttgttactag tatagtaaag ctcattttaa ttgtcaagtt cttttgaaca
     3901 tagcggatac atttttcttc taagaaccaa gcctaagttt ttttaaaaag tcacaaaatg
     3961 aggtatccct gcaaaaaacc ttttctttct tggaatttct ttgttataat gctttacaga
     4021 ggtgaaaaaa tgaaaactat tgcttttgat tctaacaagt atttaaactt gcaaagagat
     4081 catattttag aacgtatcag ccaatttgat ggcaaacttt acatggaatt tggtggtaaa
     4141 atgttagaag attaccatgc tgcccgtgta cttcctggct atgaacctga caataagatt
     4201 aaattactca aagagctcaa agaacaagtc gaaattgtaa ttgccattaa cgctaataac
     4261 attgaacatt ctaaagcgcg tggtgattta ggcatttctt atgaccaaga agtctttcgc
     4321 ttaattgaca aatttaacac gttagatatt tacgtaggtt ctgtcgttat tacccaatac
     4381 aataaccaac ccgctgcaga tgcctttcgc aagcaactca aaaaaaatgg cattgcttct
     4441 tacctgcatt atcctatcaa gagctacccg acagatatta atcatattat ctcatctgag
     4501 gggatgggga aaaatgatta catcaaaacg agtcgtaacc ttatcgttgt tacagcacca
     4561 ggccctgggt ctggaaaatt agccacttgt atatcccaaa tgtatcacga ccaaatcaat
     4621 ggggttaagt ctggctatgc taaatttgaa accttcccag tttggaatct tcctcttcat
     4681 caccctgtca atctggctta tgaggcagcc acggcagacc tagatgatgt gaatatgatt
     4741 gaccccttcc atttggaaac ttatggcaaa acggccgtta attacaaccg tgatatcgag
     4801 gtctttcctg tcttaaatcg gaccttcgag cgtattttga gcaagtctcc ttatgcctca
     4861 ccaaccgata tgggtgttaa catggttggt ttttctatcg tcaatgaaga agctgctatc
     4921 gaagcttcta aacaagaaat catccgtcgt tattaccaaa ccctcgtgga ttttaaggca
     4981 gagcgggtca cagaatctgc tgtcaaaaaa attgagctct tgatgaatga tatcggtgtc
     5041 acccctgacg atcgtcacgt tactgtagct gctcatcaaa aagcagagca aacaggccaa
     5101 cctgcccttg ctctccaact accaaatggg caaattgtga caggtaaaac atctgaactc
     5161 tttggaccaa ctgcagctgt tatcatcaat gcgattaaaa ccttggcaaa gattgataaa
     5221 accactcatt tgattgaacc cgaatacgtg aaacctattc aagggctcaa agtgaaccac
     5281 ttaggcagtc acaatccgcg gcttcattcc aatgaaattc tgattgcgtt agccattact
     5341 gctatgacta gtgaagaagc taatctagcc atgaaagaac tcggcaattt gaaaggtagc
     5401 gaagcccatt ctaccgttat cttaaccgaa gaagataaaa atgtactccg aaaacttggg
     5461 gtaaatatta cttttgaccc tgtttaccaa catcacaaac tttaccgtaa ataaactata
     5521 accacccgtc taacgggtga tttatggtat ctctcaataa aggaaaaaag tcccaattct
     5581 cagagagttg ggactttttt cctttattga ttcattaatc acccgttatg acgtcggcca
     5641 gtcacaaaca tggtcaagct tgtttttgtt agaagagctc ctgtttggtt atgaatcgtc
     5701 acatcaacca cctgcgtggt tcgacctcca tgaaccaatc gaccttcaac catcagcttg
     5761 tctcccttgt gccctgcttt taaatagtta gcattggcct gtaaggtgac agattctacg
     5821 ccagtagttc tagcaaccaa accacctact tgatcacata gagtgaaaag ataaccacca
     5881 tgagcattcc catagtaatt caaagccgtc tcagtcactt cagtacttaa aataaggtgt
     5941 cctttttcag caagttcaat ttggtaatta tcaaaaatac taataacatt taaggtcatc
     6001 tcttgtgtta aatctgacat tgtttttctc ttttctaagc ttagtctaaa agcaatacaa
     6061 gcctcattat actacaaata ggaacagaag gcagagctca tgtttcaaaa atcagtagcc
     6121 tttccatcct tttctagcgt attgaacact tccaagcata aatgaagcgc aaaactaaag
     6181 gaatcagcgc cccggttgcg ttgatcgtaa acctctacat ctgctagagt atctgctgta
     6241 aataagagtt gtccccaaag gatgcctctt aattgagcta ctgctgctaa ggcagaacat
     6301 cccatctcaa caaccgaaca cccttcttcc tggcgataag ccactttttc tttggtttct
     6361 cggtaaaaac catctgttga ccaggtgatg acctcttgat aagctaaccc ctgtgctgaa
     6421 agcgttttct ctatcggtct aagcatctta ggatcaatat caatataaca agatggtgcc
     6481 acgtaatgat aacttgttcc ttcatctcgc aaagccttaa ctggcactaa aaaacggttt
     6541 tctgcgatag gaaccaaaac gccacaggtt cctgtactga tcatttcttt aaccccataa
     6601 ccaatcagcc agtccatgaa ttgcgccgca ggagctgagc caacgggagc ttgagctagg
     6661 caaatgtctt ggcctttata aggtatctga taaacagggt aaacctttgt ggctgaaatg
     6721 aattctgcta cttttttacc ttgatggtct aaagcaaaag cttcaatctc gtcttctaag
     6781 aaagcataga cacacttagc tgtagacctt catgtgtagg tataatgacg gctgatggat
     6841 tactatcaca ttctaaaagg ggaatctcgt gtttggtaat aggcattcgt ttctccttat
     6901 ttttgtcatg tggaggcagc tgccttactc cttgattagc aacactacgc actcgacgtg
     6961 atgggtctgc gggagtcaaa aggtccagtg gaccttttga gcgtctcacc ttgaaataac
     7021 agagtgaggc ggactcttta actccgtttc tcaagtaaac ttacacactc aacttgttca
     7081 ttattatcca aacttatatt caagtcatcg tctataattg ggagcttgaa agtaattgat
     7141 tttagccatt gtccgttagg ttgtttttct tcataaactt gaatttcaga aatcaaagct
     7201 gtaattaact gtctacgctc tacatcattc atgactttat agagtttatc aaaatagatc
     7261 agaaccttat atatgttatc tcctgtgagt ttttcagctt caatagtctg tttctttgct
     7321 ttcgcatcaa ttagtgatga ttctaattca tctattttgt catacatacg atatagtcta
     7381 tcatctaaat cctgtttcct tctcttatag tgcttatctt caacatctaa attatctatt
     7441 tcctcaatta tcttaaactt tgtagaatga ctcttcctca attccttttg gtaattatct
     7501 atttcttttt ctatttcaga ggtgtccacc ttcatgttga ttttttcttg catcatagaa
     7561 gcaaatttcg gattacttac aatcttgaca atcacctctg caacagcatc atctaacaat
     7621 tcttctctaa tttgcttacg gaatgtacac ttatgacctc ttatcatctg cctatgttta
     7681 caaccatagt aataaaaatc tttatacttt gtgccatctt tctttttctt ggtacacttg
     7741 tttccaaaca ttcccgctcc acatataggg cattttacaa ttccagaaag caagtgcgtg
     7801 cgtgtatctt ttcctttatt cacatgctca tatttctttg cttgagattt tagcttaacc
     7861 tgagcagctt gccaaacttc gtcggaaact atagcttcat gtataccttc agatattaga
     7921 tattcatctt gttcaacctg cttatattca tttcttgtac catgaacttt ttctaaagtt
     7981 cttcttccaa atgctatttt cccattatat acaggattct ttaatatctt tcttataagt
     8041 cctgcatcaa acaaaggatt ctttccattc tgtcttggga tttttctaat tccatgattc
     8101 tctaagtatt tagatagccc attggctcct atcgtagtat ttacatactg gtcgaaaatc
     8161 gttcttatgg caactgcctc ttcctcattt ataaacagct tgccatcttc aagtttatat
     8221 ccatacggag caaagccacc attccatttt ccttcccttg ctttttgaat gcgaccttcc
     8281 attgtttgaa tacggatgtt ttctctttct atttcagcca cagctgataa aacagaaatc
     8341 attagtttcc cagcatcttt agatgaatca atgccatctt caacgcagat aagattaact
     8401 ccataatcct gcattatctg aagtgtagaa agaacatcag cggcatttct tgcaaatctt
     8461 gataacttaa acacaagaac aaaagacact ccatcttttc cagattttat atcttccatc
     8521 attcgattga actgttttct accttcaata gacttgccag acttcccggc atcttcatac
     8581 tctccgacaa tttcataatc gttgtaaata gcaaaagctt tcattcgtga tttttgtgcc
     8641 tctaacgaat acccctctat ctgtattgac gtagatactc gtgtatagag gtatactttt
     8701 attttttctt ttgacatagc attaacctca ttataacttt ctatatcata tataaacttt
     8761 gatttttgaa tttaagtttg gactatcatt tcaagtatat tataacactt ttattagtcc
     8821 gtctcaattt gtgtttttgc cttgtcaaaa ctatttttca tctcttgatt ttttgctggc
     8881 gttggatcgg gcagattatc taaatctaaa gcaccagcat attttgcaat cagatttgct
     8941 attaaatcag ccaatccatt ccagtcattg tccaatatat acctcctctc tataaagttt
     9001 tatatctaat aattatttgt ttaattaagt tttacgacat tgacaagtgc tttggattag
     9061 caacatagga atctcacctc cgcctctatt ccggatgagc cggcttcaac cttagaagta
     9121 tcattatcct cattttcttc atagcggata gggtatccct ccctatattc aaactcttac
     9181 ttatcgctct ctttcttctt cctttttttg cttagcagta cttgttttgc cgaattattc
     9241 agcagaaaga tcttgacgga taggttatta cgctccaaaa ataattaacg tcttgtcttg
     9301 gtctattcaa ttgttaaggt tcaaaattta tcgagagtta ttaatctttt taaaatttga
     9361 ccatcagaga aaatttatct tgatgtaaca aaattctata aattaccctc ttatacttaa
     9421 cagtgaaaag aagtctttct tggtaactaa ttttgaatag aatttactta tgtaaaaagg
     9481 tccaattccc actgcatgag tagcagtgaa aattagaccc tcttggtaac tgtcatctaa
     9541 aaatcttcta gcatttcttt aattttctaa tcgcctttta agtgtcatat ttacattttt
     9601 attatctctg gcatactttt gatacctttt tagacttaaa gtctttaata gtggctttcc
     9661 acctcttttt atctataaag attctcctac atcataattc atttttttat ttaaactttt
     9721 ctgtcttagt ttgtctttat ctttgtcata ccaatttagg attgtcgcat agtggttttg
     9781 ataggtctta ccactgcttt ccatgtatct tgatagttta tttatcatta tttctgtgtg
     9841 tgagtttagt ttttctttaa gatttttata ttcttctttg cttaacctta catttttgaa
     9901 ttctccataa aaaatggggg tggacttttt atctatctct ccctctctct ctttatctat
     9961 ctctatatct ttctctatct ctatctcttg tcggacatgg gttggactca ttaaggacaa
    10021 tgtcctctgt ttattttgtc tgtatcttct ttttttctct gcccatgctg tttctgatcc
    10081 gattaagttt ggtatttcag ttaaatagta ttcatcattt tctgttacaa cttctagtaa
    10141 gccttgattg attaaataat ttactgtgac cattacatca tcgtctgttt catctatggt
    10201 tagtgctaac tcttttataa aatcactttc tactccgtca taatagagtt tgccctcatc
    10261 ttttagactt agtaataaaa gttttaggta gattatcgtg taggtatctc ctcccgatat
    10321 tctccttagt ctttttatcc ttttgtctgt gaaaaattct tcttttagtt ttatccaata
    10381 atatcttttg tttgttgcca tatctgctcc tttcttgatt ttcgataatc gaaattcttg
    10441 atttccgatt ttcggaattc tggacttctg cttttcgtaa gtcttgttat tatggttatt
    10501 taagggtgta actttttgtt actcccttag atttctctgg tcatatcttt tttgtttggt
    10561 tttacttttt cttttacttt cctttttact ttctctttcg tcttattctt gttcttggat
    10621 aggtctttgt atttctttat ttgttttagg atactttctt tttctttttt attttctttg
    10681 gctatgactt gcttaaaggc atattccatt acttttatgt ctttggcttg gaaaaatact
    10741 tcatagtttt ggctttcttt gtttttcatt actgaaaagc ttactccaag tttgtttagt
    10801 tcttttttta agtctttgag gttgctttga tctatgctta tgttttctag ttgtcctttt
    10861 ttgtagaggt cttttatttt tatttcatcg cccataagac tttttaggtt tccatttgct
    10921 ttttctaaag tatcattcat cttttttctt atttcttttt ctaagttgat tgattctttt
    10981 gctgccttta ttgtgtatga tattatggtt tgtgctgctt gacctgcttc tttgcttatt
    11041 tcttcgttta tcatgttttc tctcctttgt ttgaattaaa aaaagggaag tataggtttt
    11101 aatttttcta tacttccctt tgcttgtttt taatttattg tttttggtgg tggaatgctt
    11161 tattttgatg ttttcatatc ttgtttaggt gtttgtacct tttatacttt taaatagctt
    11221 acaatacctt tccaccttca gcagtttgtg tgtgttcttt tgtctgatag atagtttttc
    11281 atgttggaat atataatctg tatttcttca ttgttcattg cttttatttc ttctgtgctt
    11341 ttgtaggttt tgtatgttcc atcttgatct gcttttatga gttcatctat tagctcttgc
    11401 cttttattca tctctattac ctcctagaac ggtctttatt ttcttggtca tattatagct
    11461 tggataagat atttttacca ggtcttatct ttcttgatcc attttcttgt ttttcatact
    11521 ttctctgtat tcattatctt tattgacttg gtcttggaat tttttaatct gtgctattac
    11581 acttggtttt tctccttgtt ttattagctt atctat
//
LOCUS       DATWEK010000043        11034 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.043, whole genome shotgun sequence.
ACCESSION   DATWEK010000043 DATWEK010000000
VERSION     DATWEK010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11034
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.043"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(87..1613)
                     /locus_tag="VCR92_001558"
     CDS             complement(87..1613)
                     /locus_tag="VCR92_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEP4268610.1"
                     /translation="MPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALL
                     SRSKRWSDIMLQVTGVFQTIPSLALLGLFIPLMGIGTLPAVTALVIYAIFPILQNTIT
                     GLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIG
                     AGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIMISFGITLL
                     ALLASYTPMALSQFSKGKDTVVIAGKLGAEPDILINLYKELIEDQSDISVELKSNFGK
                     TSFLYEALKSGDIDIYPEFTGTITSSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLL
                     KPFAYQNTYAVAMPEKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQY
                     GLQLSVATMEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPL
                     MKTSLLTKHPELKGILNQLAGKITEKEMQDMNYEVSVKGADANKVARDYLLKTGLIQK
                     "
     gene            complement(1606..2334)
                     /locus_tag="VCR92_001559"
     CDS             complement(1606..2334)
                     /locus_tag="VCR92_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4268611.1"
                     /translation="MIRFNNVSKTFGQTKVLQEQTFQINDREFFVLVGPSGSGKTTLL
                     KMINCLIEPSSGDILLNNVPQKELDLREMRLSIGYVLQQIALFPNLTVAENIAIIPEM
                     KQWSAEEIRQKTEELLDKVGLPAKDYLDRYPSDLSGGEQQRIGIVRAIISHPKILLMD
                     EPFSALDPISRKQLQELMLSLHKEFDMTIVFVTHDIDEAIKLGDRVAILNEGEIVQLD
                     RPEMIKTHPANAFVANLFGGDEHA"
     gene            2757..3446
                     /locus_tag="VCR92_001560"
     CDS             2757..3446
                     /locus_tag="VCR92_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEP4268612.1"
                     /translation="MKNAISILALLTSENQLEDMFIRELSHHFSHLFEVTILTSKANI
                     ESNQLSTFQGIFSFHEHDIDLPTLYFKTSQHGQGFLVTESVFDQATAVLSLSQYLTRF
                     YQKFDRHFLQYLPLQARLSDANGNIIVDNHAFNGSFLPTTDKEIEDWILAELRLSDNP
                     CKTFLLPSGSLDHIYMQHYQALKNPQGQLVGVLDTVQDIKPLLNQYLEETGQAIVGWS
                     DVTSGPSILDH"
     gene            complement(3640..4395)
                     /locus_tag="VCR92_001561"
     CDS             complement(3640..4395)
                     /locus_tag="VCR92_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEP4268613.1"
                     /translation="MGNIALVTGASAGFGRAIVEQLIADGIKVIGASRRLEKLKALET
                     SFGSDNFYPLQMDVTDTKAIDDALTSLPNQWQDITILVNNAGLALGLDKAYEADFENW
                     MTMINTNIVGLIYLTRQLLPHMVSKDDGIIINLGSTAGTIPYPGANIYGASKAFVKQF
                     SLNLRADLAGTHIRVTNIEPGLCDGTEFSKVRFNGDEARVKAIYQGAHAIQPQDIAST
                     VSWVIHQPPHVNVNRIELMPVSQSYGPQPVSRD"
     gene            complement(4522..5517)
                     /gene="pta"
                     /locus_tag="VCR92_001562"
     CDS             complement(4522..5517)
                     /gene="pta"
                     /locus_tag="VCR92_001562"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEP4268614.1"
                     /translation="MSIRSLFGGLREKILGKNMKIVFPEGNDERVVRAAARLKFEGLL
                     EPIILGQSEEVRNLLTKLGFADQDYTIINPNEYADFDKMKEAFVDIRKGKATLEDADK
                     MLRDVNYFGVMLVKMGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTSERYVFADCAINIDPTAQELAEIAVNTAETAKIFDIDPKIAMLSFSTKGSGKAPQV
                     DKVREATEIAKGLNPDLALDGELQFDAAFVPETAAIKAPDSAVAGQANTFIFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQAIESQG"
     gene            complement(5521..6426)
                     /locus_tag="VCR92_001563"
     CDS             complement(5521..6426)
                     /locus_tag="VCR92_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEP4268615.1"
                     /translation="MRFEFVADKRIKVKTLLKSHDVSKGLLAKIKYKGGNILVNGIEQ
                     NAIYLLQVGDVVTIDIPNEEPFEKLEAIPFDLDIVHEDDHFLVINKPIGFASIPSAIH
                     SNTIANFIKAYYVDNHYLDQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQTRSIE
                     KRYFALVSGNGTLPDEGDIIAPIGRSKDSIITRAVDPMGKYAKTSYKVVARYSENVHL
                     VDIKLHTGRTHQIRVHFAHIGFPLLGDDLYGGRLDLGITRQALHCHYLNFKDPFTESD
                     CSYAIHLTDDFDSVIIGLQKKDRGY"
     gene            complement(6423..7259)
                     /locus_tag="VCR92_001564"
     CDS             complement(6423..7259)
                     /locus_tag="VCR92_001564"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEP4268616.1"
                     /translation="MTQMNYTGKVKRVAIIANGKYQSKRVASKLFSVFKDDPDFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDKVRFVGIHTGHLGFYTDYRDFEVDKLIDNLR
                     KDKGEQISYPILKVAITLDDGRVVKARALNEATVKRIEKTMVADVIINHVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSIIIPKKDKIE
                     LVPKRLGIYTISIDNKTYQLKNVTKVEYFIDDEKIHFVSSPSHTSFWKRVKDAFIGEI
                     DS"
     gene            complement(7234..7905)
                     /locus_tag="VCR92_001565"
     CDS             complement(7234..7905)
                     /locus_tag="VCR92_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEP4268617.1"
                     /translation="MTLDWEEFLDPYIQTVGELKIKLRGIRKQYRKQNRYSPIEFVTG
                     RVKSIESIKEKMILRGVIEENIAQDIQDIAGLRIMVQFVDDVEEVLALLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRNLSDGVGNSDDT
                     DELYR"
     gene            7993..8571
                     /locus_tag="VCR92_001566"
     CDS             7993..8571
                     /locus_tag="VCR92_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEP4268618.1"
                     /translation="MTNLEIEYKTLLTKNEYNRLLSQMKHVTPVTQTNYYIDTKAFDL
                     KANKMSLRIRTFANSAELTLKVPEKVGNREYNVPLFLEQAKDMIKHGNLPESTALDII
                     ISKGIKPSALVTFGNLTTVRRETVIPIGKLALDYNLYANTKDYELELEVSDALQGKID
                     FDSFLSEHHIAFKYAKSKVARCINTLKKFNDK"
     gene            8711..9691
                     /locus_tag="VCR92_001567"
     CDS             8711..9691
                     /locus_tag="VCR92_001567"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEP4268619.1"
                     /translation="MTERYADKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAER
                     YSKLGLSGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQGYIIGDVSG
                     KKAILIDDILNTGKTFAEAAKILERSGATDTYAVASHGLFAGGAAEVLETAPIKEIIV
                     TDSVKTKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFSYQPKGKNNA"
     gene            9688..10815
                     /locus_tag="VCR92_001568"
     CDS             9688..10815
                     /locus_tag="VCR92_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEP4268620.1"
                     /translation="MTYFDNAATTPLSPNVIRAMTAAMQDNFGNPSSIHFYGRRANKI
                     LRECRQAIARNLGASEQQIIVTSGGTESNNMAIKGYALAHQAKGKHLITTTIEHHSVL
                     HTMAYLEERFGFEVTYLPCQNGQINLSDLKQALRDDTILVSIMYANNETGDLLPIKDI
                     GNLLKDHQAAFHVDAVQAVGKLKIIPSELGIDFLSASAHKFHGPKGCGFLYSNGQPID
                     PLLHGGDQEGKRRASTENMLGIIGMAQALTDAMTCLDQSTDHIISLRHHLISLLEGLP
                     YYINQGTHYLPHVLNIGFLGYQNTILLTQLDLAGIAVSTGSACTAGAVNPSHVLAAYY
                     GDDSSRLKESIRISFSDQNSIEDVNQLAQTLKNILGGTDGF"
     gene            10805..>11034
                     /locus_tag="VCR92_001569"
     CDS             10805..>11034
                     /locus_tag="VCR92_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEP4268621.1"
                     /translation="MAFEKEIKLKDCKYLYTISPNIKKYTLRDTTFSQTKVGHYQLIR
                     LLEKIPNSGDGFPLKITINKELTGFKLAITDQS"
BASE COUNT         3449 a         2285 c         1870 g         3430 t
ORIGIN      
        1 aaatgttcgg tttttgtatt tatgaattgt tacttcttga acttaagaga cgaaaaaatg
       61 ccagtcctat ggaccaacat ttctgtttat ttctggatta agcctgtttt caacagataa
      121 tctcgagcga ccttattagc atctgctcct ttaacagata cctcgtagtt catgtcctgc
      181 atctcttttt cagtaatttt tcccgctaat tgattaagaa tgccttttaa ttctggatgt
      241 tttgttaata aggaagtttt catcaaagga gctccctgat aaggtggaaa caactgttta
      301 tcatctttta aaactttcaa atggtatttc gtgatttcag catccgtaga gtaagcatct
      361 gttacttgga tatctcctga ttgaattgct tgataacgaa gagctggctc catcgtcgcc
      421 acagatagct gtaatccata ttgagattgc attcccttat agccatctgc tctgtcctta
      481 aattccagag taaaaccagc ctttaaagta tcagcatgcg cttttaaatc agaaatggtt
      541 tcaatctgat attccttagc caatttttct ggcatagcaa cagcatacgt attttggtaa
      601 gcaaatggct taagaagggt cagtttatct tgcttagcaa tgcctttttt agcatcctca
      661 tagacctgct tagggtcatt agacaaaggt ggtttgtcgc gtaaaagact tgatgttatg
      721 gttcctgtaa attcaggata gatatcaata tctccagatt taagggcttc atataagaag
      781 ctagttttcc caaaattaga tttcaactca acacttatat ctgattgatc ttcaattaat
      841 tccttataga gattaatcag aatatcgggc tctgctccca atttaccggc aataaccact
      901 gtatcttttc cttttgaaaa ctgactaagc gccataggag tatacgatgc tagcaatgca
      961 agtaaggtga ttccaaaact aatcataatc cgtcgcaagg aagctttctc aaggtactgt
     1021 aacaaactat tgaaaataat agctagcaga gctgaagaaa tagcccctat cagaatcagg
     1081 ttagcattat tacgatcaat ccccaataag atgaaagagc caagtccacc ggctcctatc
     1141 aaggaagcta aagtagctgt gccgataatc atgactgctg acgtccgcac acctgacata
     1201 ataacaggca ttgcaattgg aatctcaaac gtttttaacc gctcccattt ggtcattcca
     1261 aaagctattc ctgcttccac gagacttggg tcaataccat ttaatcctgt gatggtgttt
     1321 tgtaaaatcg gaaaaatcgc atagataact aaagctgtca ctgcaggcaa cgttccaatt
     1381 cccattaaag ggatgaaaag accaagcaaa gccagtgagg gaatggtttg aaaaacacct
     1441 gttacctgta acataatgtc tgaccaacgt ttgctgcgac tgagaagggc tgctaaaggc
     1501 acacctatta gcaaggcgat cataagagat aaaagggaaa tttgcaggtg ttcccccaga
     1561 gccgccagcc attcattaaa acggttttgg aaagttacaa acaaactagg catgctcatc
     1621 acctccaaat aaattggcca caaaagcatt agcagggtgg gtcttaatca tttctgggcg
     1681 atccagttgc acaatttctc cctcatttaa aatagctacg cggtctccta atttaatggc
     1741 ctcatcaata tcatgtgtca caaatacaat cgtcatgtca aattccttgt gaagactcaa
     1801 cattaactct tgcaattgtt tacgtgaaat aggatctaag gctgaaaatg gttcatccat
     1861 caatagaatt ttaggatgag aaatgatagc acgtacaata ccaatacgtt gctgttcacc
     1921 tcccgataaa tcacttgggt aacgatcaag ataatcttta gcaggtaggc ccaccttatc
     1981 caataattct tcagtttttt gtctaatttc ttcagctgac cattgcttca tctcagggat
     2041 aatcgcaata ttttcagcta ctgtgagatt ggggaaaaga gcaatttgct gcaacacgta
     2101 tccaatagat agcctcatct cacgtaaatc taactctttc tgtgggacgt tattcagtaa
     2161 aatatctcca gagcttggtt caataaggca gttaatcatt tttaaaagtg tggttttccc
     2221 cgatccgctg ggaccaacca gcacaaaaaa ttcacggtca ttaatttgaa aggtctgctc
     2281 ttgcaaaacc tttgtctgac caaaagtttt agaaacatta ttaaaacgta tcattatttc
     2341 tccaattcat tggttaaagt aacagcataa aagctgatga gttcattcaa cctgtctctc
     2401 tgtcattttt tctcaaaacg ttctgagtaa ctacaaggaa tcactgcatg ccctaccatt
     2461 tttagacaaa cgcatctact aattaaaggg actcttaggt atcctcagta aggtagaaac
     2521 taccaattct caaaaacttt ttctctcatt attttcttgt cgtttgttgt tgaccattat
     2581 aaaaagtttc ccactataag tcaaataatg agactatttc tccttacccc ttatagaaaa
     2641 acaggtcact ttgtcagcct atctctccaa aattacctta tcaaaaatcc tagacttgcc
     2701 tatgatagat aagcagatta gttgtctttt ctagaaaata cggctatcat acaattatga
     2761 aaaatgccat ttccatttta gcgctcttaa catctgaaaa ccaacttgaa gatatgttta
     2821 ttagagagct ttcccaccac ttctcacacc tttttgaggt gactattctc actagcaaag
     2881 ccaacattga gtcaaatcaa ttgtcgactt tccaaggaat tttcagtttc catgagcatg
     2941 acattgactt gcctacactc tatttcaaaa cctctcaaca tggtcaggga tttttagtga
     3001 cagaaagtgt ctttgatcaa gcaacagcag tcttatcgtt aagccaatac ctcactagat
     3061 tttaccaaaa atttgataga cattttttac agtaccttcc tttgcaagca aggttatctg
     3121 atgcaaatgg aaacatcata gtcgataatc atgcttttaa tggaagtttt ttgccaacta
     3181 ctgataaaga aatagaagat tggattcttg ctgaattgcg tttatcagat aacccttgta
     3241 aaaccttcct acttccttcg ggttcattgg atcatattta catgcagcat tatcaagctc
     3301 ttaaaaatcc tcaaggtcag ctggtgggag ttttggatac cgttcaagac attaaaccgt
     3361 tattaaacca gtatttagaa gaaactggac aagccattgt tggctggtcc gatgtcacat
     3421 caggcccttc cattttagat cactaaactt gattttaaat agggagttca gcctaaatca
     3481 tcaacgcaca agaagcaatc atgaacgctt gaagacctca aaaccttctt cttgattgct
     3541 ttttttgatg actaaatcgg taagtctcac ttataaagaa taatccatac cagtaaacca
     3601 tttttctaaa gattattatt cttatggact catcccttgc tagtcacgac taactggttg
     3661 cggtccataa ctttgcgaca ctggcatcag ctcaatacga ttaacattaa catgaggggg
     3721 ctgatgaatc acccatgata cagtcgacgc aatatcttga ggttgaatgg catgtgctcc
     3781 ttgataaatg gccttcaccc gtgcctcatc accattaaag cgaacctttg aaaattctgt
     3841 cccgtcacat agaccgggtt caatattggt cacacgtata tgggtacctg ctaaatcagc
     3901 tcgtaaattg agtgagaact gcttaacaaa agccttgcta gccccataaa tattagctcc
     3961 cggataggga attgtccctg cggttgaccc taaattaata ataataccat catctttgga
     4021 gaccatatgt ggtaataatt gacgtgtgag ataaatcaac ccaacaatat tagtgttaat
     4081 catcgtcatc caattctcaa aatcggcttc ataagcctta tcaagtccca atgccaagcc
     4141 tgcattattc actaaaatag taatatcttg ccactgattt ggtagacttg tcaaagcatc
     4201 atcaatcgct ttggtatctg tgacatccat ctgcaaaggg taaaagttgt ccgacccaaa
     4261 gctcgtttct aaggccttga gtttctcaag acgacgagaa gcaccaataa cctttatccc
     4321 atctgcaatt aattgttcga caatggctct gccaaaaccg gctgaagccc ctgttactaa
     4381 ggcaatattt cccatacatt tcctcacctt caaaaaaaac gagatggtct ggccaactcg
     4441 tttttaataa tgtcaattag tcttaggata acttctaaca catcacttag cggttagaat
     4501 cctatatcaa ggggtcttaa gttacccttg gctttcgata gcttgtgctg ctgtaataat
     4561 agctaatttg taaatatctt cagcgcttga gccacgagat aaatcattaa caggtttgtt
     4621 caatccttgt aagattggtc caatagcatc aaacattcct aaacgttgtg caattttgta
     4681 accaatattt ccagattgta agtcagggaa aataaaagta ttggcttggc cagcaaccgc
     4741 tgaatctggt gctttgatag ctgccgtttc aggaacaaag gctgcatcaa attgcaactc
     4801 accatcaagt gccaaatcag ggttcaaccc tttagcaatt tctgttgctt ctcttacctt
     4861 atcaacttga ggcgctttac cagaaccttt tgttgagaag cttaacatag caattttagg
     4921 atcaatatca aagattttag ctgtttcagc tgtgttaaca gcgatttctg ccaattcttg
     4981 tgctgttggg tcaatattga tagcacaatc agcaaacacg taacgctcac tcgtattttc
     5041 gcgattcatc aagaaaacac ctgaagttct tgaaatacct ggtttggttt taatgatttg
     5101 aagggctgga cgaacagtat cagctgttga atgaatagca ccagatacca ttccatctgc
     5161 taatcccatt ttaaccaaca taacaccaaa gtaattcaca tcacgaagca ttttatcagc
     5221 atcttcaagc gttgcttttc ctttacggat gtcaacaaaa gcttctttca ttttgtcaaa
     5281 atccgcatat tcatttggat taatgatagt atagtcttga tcagcgaagc ctaattttgt
     5341 caaaaggttg cgtacctctt ctgactgtcc aaggataatc ggttctaaga gtccttcaaa
     5401 tttcaaacga gcagctgcac ggacgacgcg ctcatcatta ccttctggga aaacaatctt
     5461 catgttttta ccaagaattt tttctcttaa accaccgaat aaactacgaa tactcattct
     5521 ttaataacct ctatcttttt tctgtaaacc tatgataacg ctatcaaagt catctgtcaa
     5581 gtgtattgca tagctacaat cactttctgt aaatggatct ttgaaattca aataatgaca
     5641 atgtaaagct tgccttgtta ttcctaagtc caaacgacct ccgtaaaggt catcccctaa
     5701 aagtggaaaa ccaatatggg caaaatgaac tctgatttga tgggtacgtc ctgtatgcaa
     5761 tttgatatcc actaaatgca cattttctga atagcgcgcc acaaccttat agctagtctt
     5821 ggcatatttg cccatagggt caactgccct ggtaataata ctatcttttg aacgcccaat
     5881 tggagcaata atatctcctt catctggcaa cgtcccattt ccagaaacca gagcaaaata
     5941 acgtttctct attgagcgag tttggagttg cttgtccaac cttgcatgag cataaccatg
     6001 cttagcaaat aacatcaagc cactcgtatc tctgtctaaa cgagtcacga tatgcacttg
     6061 ttggtctagg taatgattgt ccacataata tgccttgata aagttagcaa tggtattgga
     6121 gtggatggca cttggaatac tggcaaagcc aatgggttta ttaatcacca aaaaatgatc
     6181 atcctcgtga acaatatcca aatcaaaagg gatggcttca agcttttcaa agggctcttc
     6241 gtttggaatg tcaatggtga caacatctcc cacttgcaat aaataaatgg cattttgttc
     6301 aataccattc actaatatat taccgccctt atatttgatt ttagccaata gtcctttaga
     6361 gacatcatga ctttttaaaa gggtttttac ttttattcgt ttgtctgcta caaattcaaa
     6421 tctcatgagt caatctctcc aataaaggca tccttgaccc ttttccaaaa gctcgtatga
     6481 ctcggagagg aaacaaaatg aattttctca tcgtcgataa aatactccac cttcgtcaca
     6541 ttttttaact gataggtttt attatcaatg gaaatggtat aaattcctaa tcgttttggc
     6601 actaactcaa tcttatcttt tttgggaata atgattgatg agcccaaggt tctaaagaca
     6661 cggttattaa gactggaaat ttccgtcaat tgcagcgctt caatcgtcgg atgcaagaca
     6721 gcaccaccta aagatttatt gtaggctgtg ctccctgtcg gggtcgatac tgaaatccca
     6781 tcacctcgga agctttcaaa tttgacatgg ttaataataa catctgctac catcgttttt
     6841 tcaatacgct taaccgtcgc ttcattcaaa gcacgcgctt taaccacacg accatcatct
     6901 aaagtaatag caacttttaa aataggataa gagatttgtt ctcccttgtc ttttcttaaa
     6961 ttatcaatca atttatcaac ttcaaaatcc ctataatcgg tataaaagcc aagatgaccg
     7021 gtgtggattc ctacaaaacg taccttatct aattcttttt catacatgtg aaaggcagat
     7081 aagagcatcc catctccgcc aatagaaatc acaatatccg gatttttctt tgaaagatag
     7141 aaatcaggat catctttaaa tacggagaaa agtttggagg cgacgcgttt actttggtac
     7201 ttaccatttg caataatagc aactcgcttt accttacctg tataattcat ctgtgtcatc
     7261 actatttcct acaccatcac ttaaatttcg tgtcacgggg tcaaacaata attgagcctc
     7321 ccgaatatct tctcgaatct tacgcatttc ttcgtctaat tctaaagcaa ttttagcagt
     7381 cacttcaaga cgctttttaa tttcttctgg gaagtctcca ccatatttat aatttaaaga
     7441 atgctcaatg gtcgcccaaa agttcattgc caaagtacga atctgaatct ccgctaagac
     7501 ctttttttga ccttcaatag tatcaacagg gtactcaacc acaacatgat aagacctgta
     7561 gccactggac ttcatattgc gaatataatc tcgttcataa acaattgtca tgtcttgtcg
     7621 ttgacgcaat agagctaaga cttcttccac atcatcgaca aactgaacca taatacgtag
     7681 tccagcaata tcttgaatat cttgtgctat attttcttca ataacaccac gtaaaatcat
     7741 tttttcttta atactttcaa ttgacttaac acgtcccgta acaaattcaa tcggagaata
     7801 acgattttgc ttacgatatt gcttgcgaat accccgtagt tttattttta attcaccaac
     7861 tgtttggata taaggatcta aaaattcttc ccaatctaag gtcatctatt gtctcctttc
     7921 ttgtcaaagc caggataata atataaaatt gaaataacaa tttattatag cacaaattaa
     7981 aaggaatttc ccatgactaa cctagaaatc gaatataaaa ctctacttac aaaaaatgag
     8041 tataaccgtc ttttatctca aatgaaacat gtgacgcctg ttacacaaac taattactat
     8101 attgatacaa aagcatttga tttaaaagct aacaaaatgt cattacgtat tcgaacattt
     8161 gcaaatagcg ccgaattaac cttaaaagtg ccagaaaaag tggggaatcg tgagtacaat
     8221 gtccctcttt ttcttgaaca agcaaaagat atgattaaac atgggaatct tcctgaatca
     8281 actgctcttg atattattat ttcaaaaggt atcaaaccat ctgcactggt aacttttggc
     8341 aatttaacta ccgttcgtcg cgagacagtg ataccgatag gtaaattggc cttagactat
     8401 aacctatatg ccaataccaa agactatgaa ttagaattag aagtaagtga cgctcttcaa
     8461 ggaaagattg attttgattc ttttttatct gaacatcaca ttgctttcaa atatgctaaa
     8521 agcaaagtag ctcggtgtat taacacctta aaaaagttca acgataaata atggctaaaa
     8581 gcgacagaaa aactgaaatt tttctgtttt tctgttaaaa tagggatgtc aattaaacac
     8641 ttttgggtaa tgtgactcat taataaaaca gtttacccaa ttttattgaa gttaaggagc
     8701 taaatctatc atgactgaac gatatgctga caagcaaatc aaactgttct cactcacatc
     8761 aaatcttcca attgctgaaa aaattgctaa agctgctgga atccctcttg gaaaaatgtc
     8821 ttcacgtcaa ttttccgatg gagaaattat gatcaatatt gaagaaacag tgcgtggaga
     8881 tgatatctat attattcaat ccactagttt tcctgtcaat gataatcttt gggaattact
     8941 catcatgatt gatgcttgta aacgtgcaag tgctaatacc gtcaatattg tattgccata
     9001 ctttggttac tctcgtcaag accgtgtcgc taagccccgc gaaccgatta ctgctaaact
     9061 agtagctaat atgctgacta aagctggtat tgatcgtgta gtgacgcttg acttacatgc
     9121 tgttcaggta caaggttttt ttgatattcc agtggataac ctctttacag tccctctttt
     9181 tgcagaacgt tacagtaaat taggcttatc aggttctgat gttgttgtcg ttagccctaa
     9241 aaattctgga attaaacgtg ctagaagctt ggctgaatat cttgattccc cgattgctat
     9301 tatcgactat gcacaagatg attctgaacg tgaacaaggt tatattattg gtgatgtttc
     9361 tggtaaaaaa gccattttaa ttgatgatat tttaaatact gggaaaacct ttgcagaagc
     9421 tgctaaaatt cttgaacgct caggcgctac tgatacttac gcggtcgcta gccatggctt
     9481 atttgctggt ggagctgctg aggtattaga aacagctcca atcaaagaaa ttatcgttac
     9541 agattctgtt aaaactaaaa atcgtgtgcc agaaaacgtt acttatctta gcgccagtga
     9601 tttaatcgca gaagctatta ttcgtatcca tgaaagaaga cccttaagtc cacttttttc
     9661 ttatcaacct aaaggcaaaa ataacgcatg acttactttg ataacgccgc caccacacca
     9721 cttagtccta atgtgattag ggcgatgaca gcagctatgc aagataactt tggtaacccc
     9781 tctagtattc atttctacgg gcgccgagcc aataaaatcc ttcgtgaatg ccgacaagct
     9841 atcgctagaa acttgggggc aagtgaacag caaattatag taacgtccgg tggaactgaa
     9901 agcaataata tggccataaa aggctatgct ttagctcatc aagcaaaggg caaacatctc
     9961 atcacaacta ctattgagca ccactctgtg cttcatacca tggcctatct cgaagagcga
    10021 tttggttttg aggtcactta tttgccttgt caaaatggac aaataaattt atctgactta
    10081 aaacaagcct tgagagatga caccattttg gtaagcataa tgtatgccaa taacgaaaca
    10141 ggtgacctgt tacctattaa ggacattggg aatctgctca aagaccatca agctgctttt
    10201 catgttgatg ccgttcaagc tgttggcaaa ctcaagatta ttcctagcga acttgggatt
    10261 gactttttat ctgcttctgc tcacaaattt catggtccta aaggatgcgg ctttttatac
    10321 agtaacggac aaccaatcga ccctcttctt cacgggggtg atcaagaagg aaagcgacgc
    10381 gcaagtactg aaaatatgtt aggtattatt ggtatggcac aagctttgac tgatgctatg
    10441 acttgtcttg accaatcaac tgatcacatt atcagtttac gtcatcactt gattagcctc
    10501 ctagaaggac taccctacta tattaatcaa ggtactcatt atcttcctca tgttctcaat
    10561 attggatttt taggctacca aaatactatt ttactaacac aacttgactt agcaggcatt
    10621 gcagtatcaa ctggttctgc ttgtactgct ggagctgtta atccaagtca tgttttagct
    10681 gcgtactatg gggatgactc ttctcgttta aaagaatcaa ttcgtatcag tttttcagat
    10741 caaaatagca ttgaagatgt taatcaatta gctcaaacat taaaaaatat tttaggagga
    10801 acagatggct tttgaaaaag aaattaagct taaagactgt aaataccttt atacaatcag
    10861 tccaaacatt aaaaaatata ccctaagaga tactacattt agtcaaacta aagtagggca
    10921 ctaccaatta atacgtttac tcgaaaaaat acctaattca ggggatggtt tccctttaaa
    10981 aatcactatt aataaagaac tcacaggttt taaattagct atcaccgatc aatc
//
LOCUS       DATWEK010000044        10910 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.044, whole genome shotgun sequence.
ACCESSION   DATWEK010000044 DATWEK010000000
VERSION     DATWEK010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10910
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.044"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            19..1242
                     /locus_tag="VCR92_001570"
     CDS             19..1242
                     /locus_tag="VCR92_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEP4268622.1"
                     /translation="MPSMKYILKSLSILLIGFLGGLIAIITFNNLYPHSPSKINSGKA
                     TTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSSSLSNPYTKLFGEGRSKENKDAE
                     LSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
                     VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKN
                     ENGETVSTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGI
                     GFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQINIPTSVTGGIVVA
                     EVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKA
                     DIKLTKTTQDLTKTQ"
     gene            1301..2107
                     /locus_tag="VCR92_001571"
     CDS             1301..2107
                     /locus_tag="VCR92_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEP4268623.1"
                     /translation="MFLILSRNSLMTKELLIDLPIEDIVTNPYQPRIQFNQRELQDLA
                     TSIKSNGLIQPIIVRKSDIFGYELVAGERRLKASKMAGLKKVPAIIKKISTLESMQQA
                     IVENLQRSNLNAIEEAKAYQLLVEKKHMTHDEIAKYMGKSRPYISNTLRLLQLPAPII
                     KAIEEGKISAGHARALLTLSDDKQQLYLTHKIQNEGLSVRQIEQLVTSTPSSKLSKKT
                     KNIFATSLEKQLAKSLGLSVNMKLTANHSGYLQISFSNDDELNRIINKLL"
     gene            2340..3695
                     /gene="dnaA"
                     /locus_tag="VCR92_001572"
     CDS             2340..3695
                     /gene="dnaA"
                     /locus_tag="VCR92_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEP4268624.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLLKVDKHIATI
                     YLDQMKELFWEKNLKDVILTAGFEVYNAQISVDYVFEEDLMIEQNQTKINQKPKQQAL
                     NSLPTVTSDLNSKYSFENFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTH
                     LLNAIGNSVLLENPNARIKYITAENFINEFVIHIRLDTMDELKEKFRNLDLLLIDDIQ
                     SLAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNI
                     TPPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQI
                     DTITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQNIVLAR
                     QVAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMISQDESLRIEIETIKNKI
                     K"
     gene            3850..4986
                     /gene="dnaN"
                     /locus_tag="VCR92_001573"
     CDS             3850..4986
                     /gene="dnaN"
                     /locus_tag="VCR92_001573"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEP4268625.1"
                     /translation="MIQFSINRTLFIHALNATKRAISTKNAIPILSSIKIEVTSTGVT
                     LTGSNGQISIENTIPVSNENAGLLITSPGAILLEASFFINIISSLPDISINVKEIEQH
                     QVVLTSGKSEITLKGKDVDQYPRLQEVSTENPLILKTKLLKSIIAETAFAASLQESRP
                     ILTGVHIVLSNHKDFKAVATDSHRMSQRLITLDNTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSPSQILFRSEHISFYTRLLEGNYPDTDRLLMTEFETEVVFNTQSLRHAME
                     RAFLISNATQNGTVKLEITQNHISAHVNSPEVGKVNEDLDIVSQSGSDLTISFNPTYL
                     IESLKAIKSETVKIHFLSPVRPFTLTPGDEEESFIQLITPVRTN"
     gene            5061..5258
                     /locus_tag="VCR92_001574"
     CDS             5061..5258
                     /locus_tag="VCR92_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEP4268626.1"
                     /translation="MYQIGSFVEMKKPHACVIKETGKKANQWKVLRVGADIKIQCTNC
                     QHVIMMSRYDFERKLKKVLQP"
     gene            5588..6703
                     /gene="ychF"
                     /locus_tag="VCR92_001575"
     CDS             5588..6703
                     /gene="ychF"
                     /locus_tag="VCR92_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEP4268627.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASRGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPIADIDTINLELILADLESINKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTEDEAKVVKGLFLLTTKPVLYVANVDEDKV
                     ANPDGIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDKEEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LMTYGSEKAVKEAGRLREEGKEYVVQDGDIMEFRFNV"
     gene            6773..7342
                     /locus_tag="VCR92_001576"
     CDS             6773..7342
                     /locus_tag="VCR92_001576"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEP4268628.1"
                     /translation="MVKMIVGLGNPGSKYEKTKHNIGFMAIDNIVKNLDVTFTDDKNF
                     KAQIGSTFINHEKVYFVKPTTFMNNSGIAVKALLTYYNIDITDLIVIYDDLDMEVSKL
                     RLRSKGSAGGHNGIKSIIAHIGTQEFNRIKVGIGRPLKGMTVINHVMGQFNTEDNIAI
                     SLTLDRVVNAVKFYLQENDFEKTMQKFNG"
     gene            7345..10848
                     /gene="mfd"
                     /locus_tag="VCR92_001577"
     CDS             7345..10848
                     /gene="mfd"
                     /locus_tag="VCR92_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEP4268629.1"
                     /translation="MNILELFSQNKKVQSWHSGLTTLGRQLVMGLSGSSKALAIASAY
                     LDDQKKIVVVTSTQNEVEKLASDLSSLLDEELVFQFFADDVAAAEFIFASMDKALSRI
                     ETLQFLGNPKSQGVLIVSLSGLRTLLPNPDVFTKSQIQLTVGEDYDSDTLTKQLMTIG
                     YQKVSQVISPGEFSRRGDILDIYEITQELPYRLEFFGDDIDSIRQFHPETQKSFEQLE
                     GVFINPASDLIFEASDFQRGIEQLEKALQTAQDDKKSYLEDVLAVSKNGFKHKDIRKF
                     QSLFYEKEWSLLDYIPKGTPIFFDDFQKLVDKNARFDLEIANLLTEDLQQGKALSNLN
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDQMHQLTQYAMQEFFNQFPLLIDEIKRY
                     QKNQTTVIVQVESQYAYKRLEKSFQDYQFRLPLVSANQIVSRESQIVIGAISSGFYFA
                     DEKLALITEREIYHKKIKRRARRSNISNAERLKDYNELAVGDYVVHNVHGIGRFLGIE
                     TIQIQGIHRDYVTIQYQNSDRISLPIDQIGSLSKYVSADGKEPKINKLNDGRFQKTKQ
                     KVARQVEDIADDLLKLYAERSQQKGFSFSPDDDLQRAFDDDFAFVETEDQLRSIKEIK
                     ADMESMQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVAVLVPTTVLAQQHYENFKA
                     RFENYPVEVDVLSRFRSKKEQAETLERVRKGQIDIIIGTHRLLSKDVVFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLVREAIIREMDRGGQIFYVYNKVDTIEKKVSELQELVPEASIGFVHGQM
                     SEIQLENTLIDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYRPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFEMYSQLLEQAIASKQGKTTVRQKGNTEINLQIDAYLPDDYISDERQK
                     IDIYKRIREIQSREDYLNLQDELIDRFGEYPDQVAYLLEIALLKHYMDNAFAELVERK
                     NNQVIVRFEVTSLTYFLTQDYFEALSKTHLKAKISEHQGKIDIVFDVRHQKDYRILEE
                     LMLFGERLSEIKIRKNNSVFK"
BASE COUNT         3763 a         1748 c         2003 g         3396 t
ORIGIN      
        1 taattcggag gacaaaacat gccaagtatg aaatatatct taaaatcctt aagtatttta
       61 ctaattggat ttttaggagg attaatagca attattacat tcaataatct ctacccacat
      121 tctccttcaa aaataaattc aggtaaggca acaactagta atatggtttt taacaacaca
      181 accaatacta ctaaagctgt caaagctgtt caaaatgcag ttgtatcagt tattaattat
      241 caagataacc cttcttcatc cctttctaac ccttatacaa aactctttgg agaagggcgt
      301 tcaaaagaga ataaggatgc tgaattatct atttttagtg aaggatctgg ggtcatttat
      361 cgaaaagatg gcaactccgc ttacgttgtt actaataacc atgttatcga cggagctaaa
      421 cgaattgaaa ttcttatggc agacggatct aaagttgttg gtgaattagt tggagctgat
      481 acttattcgg atttagctgt tgttaagatc tcttcagata agataaaaac agtagctgaa
      541 tttgcagact ctacaaaact aaatgttgga gaagttgcta ttgctatcgg cagcccacta
      601 ggaacacaat acgctaattc tgttactcaa ggaatcgtct ctagtttaag tcgtactgta
      661 actttaaaaa acgagaatgg tgagactgtc tcaacaaatg ctattcagac agatgctgct
      721 attaaccctg gaaactctgg tggaccacta attaatattg aggggcaagt aatcggaatt
      781 aattcaagta aaatttcttc taccccaact ggtagcaacg gtaatagtgg tgctgttgaa
      841 ggaattggtt ttgctatccc atctactgac gttattaaaa ttattaaaca actagaaact
      901 aatggtgaag ttatcagacc tgctcttgga atatccatgg tcaatttaaa tgacttatcc
      961 acaaatgctc ttagccaaat taatattcca actagtgtaa ctggtggtat tgtagtagca
     1021 gaagttaagg aaggaatgcc ggcatctggc aaacttgctc agtacgatgt gattacagaa
     1081 attgatggca aaacagttaa ttcaattagt gatttacaaa gtagtctata cggacacgat
     1141 attaatgata ctattaaagt aactttttat agaggaacta caaagaaaaa agcagatatc
     1201 aaattaacaa aaactactca agatttgact aaaacgcagt aaacaagcta cctaaatact
     1261 attacatttt atcacataaa acagtccaaa ggactgtttt atgtttctta ttctatccag
     1321 gaactccctt atgacaaaag aattattgat agacctacca attgaagata ttgttacaaa
     1381 tccctatcaa ccaaggatac aatttaatca aagagaactc caagacctag caacttctat
     1441 taaatcaaac ggcctcattc aacctattat tgttcgaaaa tctgacattt ttggctatga
     1501 gttagttgct ggagaacgac gacttaaagc ttcaaaaatg gctggtctaa aaaaagttcc
     1561 agctatcatc aagaagatct ctacactcga gagtatgcaa caagctatag ttgaaaattt
     1621 acaacgttct aaccttaacg ctatcgaaga agctaaagcc tatcagttat tggttgaaaa
     1681 aaaacacatg actcacgatg agattgctaa atatatggga aaatcaagac cttatattag
     1741 caatacctta cgtctgttac aactcccagc acctatcatt aaagcaattg aagaaggaaa
     1801 aattagtgcg ggacacgcgc gtgctctttt aactttgagt gatgataagc aacaactgta
     1861 cctcactcat aaaatacaaa atgaaggcct aagtgttagg caaattgagc aactggttac
     1921 ttctactcca agttcgaagc tatctaaaaa aactaaaaat atttttgcca cttctttaga
     1981 gaaacaattg gctaaatcat tgggactctc tgtcaatatg aagctgacag caaaccatag
     2041 tgggtacctt cagatatctt tttccaatga tgatgaatta aacagaatta tcaacaagct
     2101 actttagctt gttgatattc tgttttttct tttttagttt tccacatgaa aaatagttga
     2161 aaacaatagc ggtgtcacat taaaatggct tttccacagg ttgtggagaa cccaaattaa
     2221 cagtgttaat ttattttcca caggttgtgg aaaaactaac tattatccat cgttctgtgg
     2281 aaaactagaa tagtttatgg tagaatagtg ctagaattat ccacaagaag gaacctagta
     2341 tgactgaaaa tgaacaaatt ttttggaaca gggtcttgga attagctcag agtcaattaa
     2401 aacaggcaac ttatgaattt tttgttcatg atgcccgtct attaaaggtc gataagcata
     2461 ttgcaactat ttacttagat caaatgaaag aactcttttg ggaaaaaaat cttaaagatg
     2521 ttattcttac tgctggtttt gaagtttata acgctcaaat ttctgttgac tatgttttcg
     2581 aagaagacct aatgattgag caaaatcaga ccaaaatcaa tcaaaaacct aagcagcaag
     2641 ccttaaattc tttgcctact gttacttcag atttaaactc gaaatatagt tttgaaaact
     2701 ttattcaagg agatgaaaat cgttgggctg ttgctgcttc aatagcagta gctaatactc
     2761 ctggaactac ctataatcct ttgtttattt ggggtggccc tgggcttggg aaaacccatt
     2821 tattaaatgc tattggtaat tctgtactat tagaaaatcc aaatgctcga attaaatata
     2881 tcacagctga aaactttatt aatgagtttg ttatccatat tcgccttgat accatggatg
     2941 aattgaaaga aaaatttcgt aatttagatt tactccttat tgatgatatc caatctttag
     3001 ctaaaaaaac gctctctgga acacaagaag agttctttaa tacttttaat gcacttcata
     3061 ataataacaa acaaattgtc ctaacaagtg accgtacacc agatcatctc aatgatttag
     3121 aagatcgatt agttactcgt tttaaatggg gattaacagt caatatcaca cctcctgatt
     3181 ttgaaacacg agtggctatt ttgacaaata aaattcaaga atataacttt atttttcctc
     3241 aagataccat tgagtatttg gctggtcaat ttgattctaa tgtcagagat ttagaaggtg
     3301 ccttaaaaga tattagtctg gttgctaatt tcaaacaaat tgacacgatt actgttgaca
     3361 ttgctgccga agctattcgc gccagaaagc aagatggacc taaaatgaca gttattccca
     3421 tcgaagaaat tcaagcgcaa gttggaaaat tttacggtgt taccgtcaaa gaaattaaag
     3481 ctactaaacg aacacaaaat attgttttag caagacaagt agctatgttt ttagcacgtg
     3541 aaatgacaga taacagtctt cctaaaattg gaaaagaatt tggtggcaga gaccattcaa
     3601 cagtactcca tgcctataat aaaatcaaaa acatgatcag ccaggacgaa agccttagga
     3661 tcgaaattga aaccataaaa aacaaaatta aataacatgt ggaaaagaat atcttttatg
     3721 aaatagttat ccacaagttg tgaacaacca tttagtcttg gattctctcg tttatttaga
     3781 gttatccact atatacacaa gacctactac tactacttat tattatactt attaaataaa
     3841 ggagttctca tgattcaatt ttcaattaat cgcacattat ttattcatgc tttaaatgca
     3901 actaaacgtg ctattagcac taaaaatgcc attcctattc tttcatcaat aaaaattgaa
     3961 gtcacttcta caggagtaac tttaacaggg tctaacggtc aaatatcaat tgaaaacact
     4021 attcctgtaa gtaatgaaaa tgctggtttg ctaattacct ctccaggagc tattttatta
     4081 gaagctagtt tttttattaa tattatttca agtttgccag atattagtat aaatgttaaa
     4141 gaaattgaac aacaccaagt tgttttaacc agtggtaaat cagagattac cttaaaagga
     4201 aaagatgttg accagtatcc tcgtctacaa gaagtatcaa cagaaaatcc tttgatttta
     4261 aaaacaaaat tattgaagtc tattattgct gaaacagctt ttgcagccag tttacaagaa
     4321 agtcgtccta ttttaacagg agttcatatt gtattaagca atcataaaga ttttaaagca
     4381 gtagcgactg actctcatcg tatgagccaa cgtttaatca ctttggacaa tacttcagca
     4441 gattttgatg tggttattcc aagtaaatct ttgagagaat tttcagcagt atttacagat
     4501 gatattgaga ccgttgaggt atttttctca ccaagccaaa tcttgttcag aagtgaacac
     4561 atttcttttt atacacgcct cttagaagga aattatcccg atacagatcg tttattaatg
     4621 acagaatttg agacggaggt tgttttcaat acccaatccc ttcgccacgc tatggaacgt
     4681 gccttcttga tttctaatgc tactcaaaat ggtactgtta agcttgagat tactcaaaat
     4741 catatttcag ctcatgttaa ctcacctgag gttggtaagg taaacgagga tttagatatt
     4801 gttagtcagt ctggtagtga tttaactatc agcttcaatc caacttacct tattgagtct
     4861 ttaaaagcta ttaaaagtga aacagtaaaa attcatttct tatcaccagt tcgaccattc
     4921 accctaacac caggcgatga ggaagaaagt tttatccaat taattacacc agtacgaaca
     4981 aactaagtaa gaaaaagctc ccttttagga gtttttttgt tattataaat attaacgata
     5041 atataagtgg agaaaaggga atgtatcaaa ttggatcatt tgttgaaatg aaaaaacctc
     5101 atgcttgtgt aattaaagaa actggtaaaa aggctaatca atggaaggta ctgagagtag
     5161 gagctgatat taaaattcag tgtactaact gtcagcatgt gattatgatg agtcgttatg
     5221 attttgagcg aaaattaaaa aaagtactgc aaccatgaaa gtccttttaa ataaataatt
     5281 ctagctatat ttgcaaccaa tactttccta aaaaattgct agtatgccgt tggaaaatta
     5341 gctattctaa tgttatcgaa agaagaaaga tggccattga caatgacgaa agttgtagca
     5401 cagttactta gtttctcggc aaactatatc aaaatgagaa taatacacca aactttgata
     5461 atttaaatga aggtgaaaga gtggcataat gataagcaaa tctgaaattt tcttcttatt
     5521 cataccgctt tttcttctat tttttggtat aataatcttg attgaaattt gaatggagat
     5581 tcgctaaatg gctttaacag caggtattgt aggcttacca aatgttggta aatcaacctt
     5641 atttaacgca attacaaaag caggagcaga agctgctaat tatccttttg cgactattga
     5701 tcccaatgtt ggtatggtag aggttccaga tgagcgtctg caaaaattga cagaattgat
     5761 tacacctaaa aaaacagttc cgacaacctt tgaatttact gatattgcag gtatcgttaa
     5821 aggtgcttct agaggggaag gtctaggaaa taaattttta gctaatattc gtgaagtcga
     5881 tgctattgtt catgtggtac gtgcttttga tgatgaaaat gtcatgcgtg aacaaggtcg
     5941 tgaggatgct ttcgttgatc ctatagcaga tattgacact attaatcttg aattaatctt
     6001 agctgattta gagtcaatca ataaacgtta tgcgcgtgtt gaaaaaatgg cacgaactca
     6061 aaaagataaa gaatcagtag cagagtttaa tgttttgcaa aagattaaac ctgttttgga
     6121 agatgggaaa tcagctagga caattgagtt tacagaagat gaagcaaaag ttgttaaagg
     6181 tctcttttta ttaacaacta aacctgtttt atatgtagct aatgtcgatg aagataaagt
     6241 tgctaatcca gatggtattg attatgtcaa acaaattcgt gactttgcag ctactgaaaa
     6301 tgctgaagta gttgttatct cagcgcgtgc agaagaagaa atttcagagc ttgacgatga
     6361 ggataaagaa gaatttttgg aagctatcgg tcttactgaa tcaggcgttg ataaattaac
     6421 cagagcagct tatcatctct taggccttgg aacctatttt acagcaggtg aaaaagaggt
     6481 tcgtgcttgg acgtttaagc gtggtataaa agctccacaa gctgctggta ttatccattc
     6541 agattttgaa agaggtttta ttcgtgcagt aaccatgtct tatgatgatc taatgaccta
     6601 cggttcagaa aaagccgtca aagaagctgg acgcttgcgt gaagaaggaa aagaatatgt
     6661 tgtccaagat ggggacatca tggaattcag atttaatgtg taattatatt aaaacaatat
     6721 cagaaggttg gaagaacatt ccagcccttt tggcatttta gaaagagaaa atatggtaaa
     6781 aatgattgtt ggtctgggaa atccaggctc taaatatgaa aaaacaaagc acaatattgg
     6841 ttttatggct attgacaata ttgtcaagaa ccttgacgtt acctttacag atgataaaaa
     6901 ttttaaagca cagataggaa gtacttttat taatcatgaa aaagtttact ttgtgaaacc
     6961 tactactttt atgaataata gcggcatagc agtaaaagca ttactaacct actataatat
     7021 tgacataaca gatttaattg ttatctatga tgatttagac atggaagtca gtaaattacg
     7081 tttacgtagt aagggttcag caggaggaca taatggcatt aagtcaatca ttgcccacat
     7141 tggaactcag gaatttaacc gaatcaaagt tggtattgga cgacctttaa aaggtatgac
     7201 tgttattaac catgtgatgg gccaattcaa taccgaagat aatattgcta tttcgttaac
     7261 tcttgacaga gttgtcaatg ctgtcaagtt ttatttacaa gaaaatgatt ttgaaaaaac
     7321 aatgcagaaa tttaatggat aatcatgaat attttagaat tatttagtca gaataagaaa
     7381 gtccaatcct ggcactctgg attaaccacc ttaggaagac aactggtaat ggggttatcg
     7441 ggttcaagta aagcattggc tatagcttcc gcttatttag atgatcaaaa aaaaatagtt
     7501 gtggttacat caactcaaaa tgaggttgaa aaattagcca gcgatttatc tagtttactt
     7561 gatgaagaac ttgttttcca attttttgca gacgatgtgg ctgcagcgga atttatcttt
     7621 gcgtcaatgg ataaagctct atcaagaata gaaaccctgc aatttttagg gaatcctaaa
     7681 tctcagggcg ttttaattgt tagtttatca ggcttaagaa ctttattgcc aaacccagat
     7741 gtttttacaa agagtcagat tcaactaaca gttggagaag attatgatag tgatactctt
     7801 actaaacaac tgatgacaat tggctatcag aaggtctcac aggtcattag tccgggagaa
     7861 tttagccgtc gaggggatat tttagatatc tatgagatta cacaagaatt gccttatcga
     7921 ttggaatttt ttggcgatga tattgatagt attaggcaat ttcatccaga aactcaaaaa
     7981 tcttttgaac aactagaagg tgtttttatt aatccagcaa gtgatcttat ttttgaggct
     8041 agtgattttc aacgtggcat tgagcaatta gaaaaggctc tacaaacagc acaagatgat
     8101 aaaaaatctt atttagaaga tgtattagct gtttcaaaaa acggttttaa acataaggat
     8161 atccgtaaat ttcaatcatt attttacgaa aaagagtggt cattattaga ttatattcct
     8221 aagggaacgc caatcttttt tgatgatttt caaaaactag ttgataaaaa tgcaagattt
     8281 gatttagaga ttgctaatct cttgacagaa gatttacagc aaggaaaggc tctttccaat
     8341 cttaactact ttgcagataa ttatcgagag cttaggcact ataagccagc gaccttcttt
     8401 tcaaattttc ataagggact tggaaatatc aaatttgatc agatgcatca gctaactcag
     8461 tatgccatgc aggaattttt taatcaattt cctttgttga ttgatgagat taaacggtat
     8521 caaaaaaatc aaacaacggt tattgtacag gtagagtctc agtatgctta caaacgactt
     8581 gaaaaatctt ttcaagatta ccaatttcgc cttcctttag tgagtgctaa tcaaattgtt
     8641 tcacgtgaat cacaaattgt aattggagct atctccagtg gtttttattt tgctgatgaa
     8701 aagttagcgt taatcacaga gcgtgaaatt tatcataaaa agatcaaacg acgcgctaga
     8761 cgatctaata ttagcaatgc tgagcgtttg aaagattaca atgagttagc agtaggtgat
     8821 tacgtggttc ataatgtcca tggtatcggt cgctttcttg gaattgaaac gattcagatt
     8881 cagggaatcc atcgagatta tgttactatt caatatcaaa attcagaccg tatttctctt
     8941 ccaattgacc aaattggtag cttatcaaag tacgtttctg ctgatggaaa agaacctaaa
     9001 attaataaac tcaatgatgg tcgtttccaa aagacaaagc aaaaggtcgc tagacaagta
     9061 gaggatattg ctgatgacct tctaaaatta tatgctgaaa gaagtcagca aaaaggattt
     9121 tcattttcac cagatgatga cttgcagcgc gcttttgatg atgattttgc ttttgtagaa
     9181 acagaagatc aacttaggtc tataaaggaa attaaagctg atatggagag catgcagcct
     9241 atggatcgtc ttttagtagg cgatgtagga tttggtaaga cagaagtagc tatgagggca
     9301 gcctttaaag cggtgaacga tcacaaacaa gtagctgtct tagttccaac cacagtcttg
     9361 gcccagcagc attatgaaaa cttcaaagca cgctttgaaa attaccctgt tgaggttgac
     9421 gtcttaagtc gtttccgtag taaaaaagag caagctgaaa cactagaacg tgtacgaaaa
     9481 ggtcaaattg acattattat cggaacccat cgactcctat caaaagatgt ggtcttttct
     9541 gatttaggat tgattgtgat tgatgaggaa caacggtttg gtgttaagca taaagaaact
     9601 ttaaaggaat taaaaactaa ggttgacgtc ttaaccttaa cagctactcc gattcctaga
     9661 accttacaca tgtctatgtt aggtatccga gatttatcgg ttattgagac cccaccaacc
     9721 aatcgttatc ctgttcaaac ctatgttttg gaaaataatc caggtctcgt tagagaagct
     9781 atcattcgtg aaatggatcg tggaggacaa attttttacg tttacaataa agttgacact
     9841 attgaaaaga aagtttcaga gctacaagaa ttagtcccag aagcttctat aggttttgtt
     9901 catgggcaaa tgagtgaaat tcaacttgaa aataccttga ttgactttat aaatggtgat
     9961 tatgatgtcc ttgtggctac aacaatcatc gaaacaggag ttgacatttc taatgtaaac
    10021 actttgttta ttgagaatgc tgatcatatg ggattgtcaa ctttatatca actacgaggg
    10081 cgcgtcggaa gaagtaatcg tattgcttat gcttacctga tgtatcgtcc tgataaggtc
    10141 ctaacagagg tttctgaaaa gcgtttagag gctattaaag gctttactga attaggttca
    10201 ggcttcaaga ttgctatgcg agatttgtct atacgaggag caggtaatat tttaggggct
    10261 tctcagagtg gctttattga ttcggtcggt tttgaaatgt attctcagtt attggaacag
    10321 gctattgcta gcaagcaagg aaaaacgact gttcgccaaa aaggtaatac tgaaatcaat
    10381 cttcagattg acgcctattt gccagatgat tacatatcag atgagcgtca aaaaattgac
    10441 atttacaagc gtattcgaga aattcaatca agagaagatt atctcaattt gcaggatgag
    10501 ctgatagatc gttttggaga gtatcctgat caagttgcct atttgttaga gatagctctg
    10561 ctaaaacatt atatggacaa tgcctttgcg gaattagttg aacgcaaaaa taatcaggtc
    10621 attgttcgat ttgaagtaac ttctttaact tatttcttga ctcaggatta tttcgaagcc
    10681 ttatcgaaaa cccatcttaa agctaaaatt agtgaacatc aggggaaaat cgatatcgtc
    10741 tttgacgttc gccatcaaaa agattataga attttagaag aattgatgtt atttggagaa
    10801 aggcttagtg agataaaaat cagaaaaaac aattcagttt ttaaataata atttgaaaca
    10861 acttttagac tgaatagtat taatgacaat ggaacgaact agctctttat
//
LOCUS       DATWEK010000045        10882 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.045, whole genome shotgun sequence.
ACCESSION   DATWEK010000045 DATWEK010000000
VERSION     DATWEK010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10882
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.045"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            15..752
                     /locus_tag="VCR92_001578"
     CDS             15..752
                     /locus_tag="VCR92_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEP4268630.1"
                     /translation="MGKEIKVKYFLRRSAFGLVAVSASVLVGSTVSAVDSPIEQPRII
                     PNGGTLTNLLGNAPEKLALRNEERAIDELKKQAIEDKEATTAIEAASSDALEALVDQA
                     DALQSEEAAVVQSDTAASDALEALADQTDALQSEEAAVVKADTAASDALEALADQTDA
                     VQSEEASVVKADTAASDAWEKAATPTALDVKKTKDTTPVVKKEERQNVNTLPTTGEES
                     NPFFTAAALAITVSTGALVVSSKCKEN"
     gene            990..1532
                     /locus_tag="VCR92_001579"
     CDS             990..1532
                     /locus_tag="VCR92_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP4268631.1"
                     /translation="MDIWTKLAVFAFFETPKVILRPFRYEDHWDFYSMVNDTKNLYYV
                     FPEQKTKAASDYLLVHSFIKFPLGQWAIEDKATHQVIGSIRIEHYDAKTRCADIGYFL
                     NYAFWGQGIMTEVVIKLVYLSFHEFGLKTLRIITHLENKASQKVAKKAGFQLKTCFKG
                     SDRNTHKICIYKMYQLTNDR"
     gene            1541..2824
                     /locus_tag="VCR92_001580"
     CDS             1541..2824
                     /locus_tag="VCR92_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEP4268632.1"
                     /translation="MSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYSEIARISDSEVLAGHAGLGHEFSRFSIGA
                     MTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVSKRVIEMANNQRIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIPITDYGYLCENSSVEEFNTLIKK
                     TRQVRFPVLDYKRKVIGVVSMRDVVDQLPTTKLTKVMSKNPITARPNTSLANISQKMI
                     FEDLNMLPVTDEENNLLGMITRRQAMENLPNHQPNNPYTYSEQILSNLEETVDYYQVV
                     VEPTMIDSAGNMSNGVISEFLKEISIRALTKKHQKNIIIEQMMVYFLHAIQIEDELKI
                     YPKIITENRRSSTIDIEIFVDDQVIAKAIITTKIN"
     gene            2840..3700
                     /locus_tag="VCR92_001581"
     CDS             2840..3700
                     /locus_tag="VCR92_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEP4268633.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRDIIKPGVDMWEVEAYV
                     RRRCKEDNVLPLQIGVDGHMMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLS
                     EPLDKSIVDVAALDFDNVPEMKKWTRSYTGGLADSCWAYAVGTPSDEIKQLMDVTKEA
                     MYRGIEKAVIGNRIGDIGAAVQEYAESFGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEIDTDIKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            3702..4667
                     /locus_tag="VCR92_001582"
     CDS             3702..4667
                     /locus_tag="VCR92_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEP4268634.1"
                     /translation="MAEKKWFDKVLSKWQYEPIQVFMRHLQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDIADLLRLMKQNLPKDIFRPASAIVENIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAINKAYGASQHRDFFIGHLVGLLTSLIILFLLAFALIFSTF
                     SKAAIQVLDKHYHLSDNITTIFLLLIQPITVLIIFVGLMLLYFLLPNVKIKKIRYILP
                     GTLFTSFVMTFLSNLVGNYVVYNVERMVDIKMFGSVMIFIIMLWFIFLARILILGAIF
                     NATYQEMSLGKLEGRSGDMIAILKKTLGNDSDLSPSQSIEDSHTD"
     gene            4778..6061
                     /gene="aroA"
                     /locus_tag="VCR92_001583"
     CDS             4778..6061
                     /gene="aroA"
                     /locus_tag="VCR92_001583"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEP4268635.1"
                     /translation="MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLK
                     GEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLTAPCQTLNMGNSGTSMRLIAGLL
                     AGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITY
                     TLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVG
                     PQQLTAQEITVPGDISSAAFWLVAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQI
                     VYEDMNKKEQVTSIRVVYSHLKGTIISGGLIPRLIDELPIIALLATQAQGTTCIKDAQ
                     ELRVKETDRIQVVTDILNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAI
                     AALLVKQGQVHLDKEEAIMTSYPTFFKDLERLCHD"
     gene            6054..6545
                     /locus_tag="VCR92_001584"
     CDS             6054..6545
                     /locus_tag="VCR92_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEP4268636.1"
                     /translation="MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFE
                     QHGEIAFRTIESQVLKDLLFANDNSIIVTGGGVVVLQENRQLLRKNHQHNILLVASFE
                     TLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANII
                     EGY"
     gene            6753..8204
                     /locus_tag="VCR92_001585"
     CDS             6753..8204
                     /locus_tag="VCR92_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEP4268637.1"
                     /translation="MTKYPMGGLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEI
                     GRAYAPSKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPKED
                     RYLNKKTKLTARRPIDTPQPIDEDDAFLTESVARCALPRSQKRKHKKKGCMKWFFNIL
                     GLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQETQDGTNILVLGSDQRVT
                     QGSTDARTDTIMVVNVGNHAKKIKMVSFMRDTLINIPGYSYNDNSYDLKLNSAFNLGE
                     QEDHHGAEYVRRALKHNFDIDIKYYVMVDFETFAEAIDTLFPNGVKIDAKFATVGGVA
                     VDSVEVPDDLRMKNGVVPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVM
                     SAVMSQIKDPTKLFTGSAAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPE
                     NGDWVDEYDMYGGQALYIDFDKYQKTLAKLGLR"
     gene            8286..9920
                     /gene="rlmD"
                     /locus_tag="VCR92_001586"
     CDS             8286..9920
                     /gene="rlmD"
                     /locus_tag="VCR92_001586"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEP4268638.1"
                     /translation="MLKKNDIIQVAISDLSHEGAGVAKHDGFVFFVDNALPEEVIDMR
                     VLKVNKNSGFGKVEAYHYLSPARNADVNLTYLRTGIADLGHLTYEDQLTFKKKQVQDS
                     LYKIAGISDVTVESTIGMTEPLAYRNKAQVPVRRVNGQLETGFFRKHSHDLIPISDYY
                     IQDKEIDRLINFTRDLLRRFDIKPYDETEQTGLLRNIVVRRGHYSGEMMLVLVTTRPK
                     VFRVDQVIEKIVEAFPAVVSIIQNINDKNTNAIFGKDFKTLYGKDTITDSMLGNNYAI
                     SAQSFYQVNTVMAEKLYQTAIAFSDLSKDDIVIDAYSGIGTIGLSFAKTVKAVYGVEV
                     IEAAVRDAQHNAALNGITNAYFVADTAEHAMATWAKDGIKPSVILVDPPRKGLTESFI
                     QASVAMGPQKITYVSCNPATMARDIKRYQELGYKLAKVQPVDLFPQTHHVETVALLSK
                     LGVDKHINIEIEMDELDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKRKCGIEL
                     REHYNKSKKEKQIIPQCTPEKEEAIMDALRHFKMIE"
     gene            10076..10612
                     /locus_tag="VCR92_001587"
     CDS             10076..10612
                     /locus_tag="VCR92_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEP4268639.1"
                     /translation="MRSYESKEELKNEIKKTFEKYISEFDNIPEELKDKRLEEVDRTP
                     AENLAYQVGWTTLVLKWEEDEKKGIDVKTPSDKFKWNQLGELYQWFTDTYAHKSLYEL
                     KEQLTENVKKIYLMIDELTDEELFKPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKLVLYIEKYK"
     gene            10632..>10882
                     /locus_tag="VCR92_001588"
     CDS             10632..>10882
                     /locus_tag="VCR92_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyketide cyclase"
                     /protein_id="HEP4268640.1"
                     /translation="MAVAKIKVTLNCPIEKVWDKVTDLRDFSWRSDIKDIKIIDDKNF
                     VEITKDGIETNFKVIKCTKHQCWSFEIENANIKGTWIGK"
BASE COUNT         3684 a         1773 c         2231 g         3194 t
ORIGIN      
        1 aaaaaggaga aacaatggga aaagaaataa aagtgaaata ctttttgcgt agatcagctt
       61 ttggattagt tgcggtgtca gcatcagtat tagtcggttc aacagtatct gctgttgact
      121 cacctatcga acagcctcga attattccaa atggcggaac cttaactaat cttcttggca
      181 atgctccaga aaaactggca ttacgtaatg aagaaagagc cattgatgaa ttaaaaaaac
      241 aagctattga ggataaagaa gctacgacag ctatagaagc agcaagttca gatgccttag
      301 aagcattagt ggatcaagca gacgctttac aatcagaaga agctgcagta gttcaatcag
      361 ataccgctgc tagtgatgcc ttagaagcat tggcggatca aacagacgct ttacaatcag
      421 aagaagctgc ggttgttaaa gcggataccg ctgctagtga cgccttagaa gcattggcgg
      481 atcaaacaga cgctgtacaa tcagaagaag cttcagttgt taaagcagat accgctgcta
      541 gtgacgcctg ggaaaaagca gcaactccaa ccgctttaga tgttaagaaa actaaagata
      601 caacacctgt agttaaaaaa gaagaaagac aaaacgttaa tacccttcct acaactggtg
      661 aagagtctaa cccattcttt acagctgctg cgcttgcaat aacggtaagt acaggtgcgt
      721 tagttgtaag ttcaaagtgc aaagaaaatt agttgctatt tgttctagca aatgaaacaa
      781 gagaatcgaa agattctctt tttctgatat ttaaaaatgc tacagtttat aatagcttga
      841 aagactaaat gttctcaaac tcattagaac aagctttaat aaaactaacc cagttgtatc
      901 aaaggataga taaagactaa gactgttata gaatatttgc aaaagatttg ttataatgga
      961 cccaatacag gtattgtgaa aggtataata tggatatttg gacaaagctt gcagtgtttg
     1021 ctttttttga gactccgaaa gtaatattac ggccttttcg ctatgaagat cattgggatt
     1081 tttacagcat ggttaacgac actaaaaacc tttattatgt ttttccagaa caaaaaacta
     1141 aggcagcaag tgactatctt ttagtacata gttttataaa gtttccttta ggtcagtggg
     1201 caatagaaga taaagcaacc caccaagtaa taggttctat tagaattgag cattatgatg
     1261 ctaaaacgcg ttgtgctgat attggctatt ttttaaacta tgccttttgg ggacaaggaa
     1321 ttatgacaga agtcgtaata aaacttgttt atttatcttt tcacgaattt ggtctcaaaa
     1381 cgttgcgtat tataactcat ttagaaaata aggccagcca gaaagtagct aaaaaagcag
     1441 gttttcaact aaaaacctgt tttaaaggaa gtgatcgtaa tactcataaa atctgcattt
     1501 ataaaatgta ccaactaact aatgataggt gataatcatt atgagcaaac atcaagatat
     1561 tttagattat ttagaaaaac ttgctattgg taaaaaagtg agtgttagaa gcatttcaaa
     1621 ccacttaaaa gtaagcgatg gaacagccta ccgtgctatt aaagaggcag aaaatcgagg
     1681 tattgtcgaa accaaaccaa gaagtggaac tgttcgtatt gaaaaaaaag gacgggttcg
     1741 tattgaccgt ctgacctatt ccgaaattgc tcggatcagt gattcggaag tgctagcggg
     1801 acatgctggt ttaggacatg aattcagtag gttttcaatt ggtgctatga ctcaacaaaa
     1861 tattcgtcgt tacttggtca aaggagggtt attaatagtt ggggatcgtg aaacgattca
     1921 actcttagct cttgaaaacc ataatgccat tttggtgacg ggcggatttc cagtatccaa
     1981 acgtgttatt gaaatggcaa ataaccaacg aatcccagtt atggtaactc attatgatac
     2041 ctttactgtg gcaacaatga ttaatcacgc gctatctaat attcgtatta aaacagatct
     2101 caaaacagtt gaacaggtaa tgatacctat tacagattat ggttaccttt gcgaaaacag
     2161 ctctgttgaa gaattcaata cattaataaa aaaaacacga caagtcaggt ttcctgtatt
     2221 agattataaa agaaaagtga ttggtgtagt tagtatgcgt gatgtggtgg atcagttgcc
     2281 aacaactaag cttaccaagg tcatgtctaa aaatccaata acggctagac caaatactag
     2341 tcttgctaat attagccaga aaatgatctt tgaagattta aacatgttac ctgtcactga
     2401 cgaagaaaac aatttacttg gtatgattac tcgtagacaa gcaatggaaa atttgccaaa
     2461 tcaccaaccc aataacccct atacttatag tgagcaaata ctttctaacc ttgaagaaac
     2521 ggttgattat taccaagtag tagttgagcc aacaatgatt gatagtgctg gtaacatgtc
     2581 aaacggtgtt atttcagagt tcttaaagga aattagtatc agagccctca cgaaaaagca
     2641 ccaaaaaaat atcattatcg aacaaatgat ggtatacttt ttacatgcta ttcaaattga
     2701 ggatgaatta aaaatatatc ctaaaatcat tactgaaaat agacgaagca gcaccattga
     2761 tattgaaatt tttgtggatg atcaagtgat tgctaaagct attattacaa cgaaaataaa
     2821 ttagaggagt aacaaaacaa tgataacatt aaaatcagcc cgtgaaatag aagcgatgga
     2881 tagagcagga gacttcttag caggtatcca tattggctta agggatatta ttaagcctgg
     2941 tgtggatatg tgggaagtgg aagcatatgt tcgtcgccgt tgtaaagaag acaacgttct
     3001 tcctttgcaa ataggggttg atggtcacat gatggactat ccttatgcga cctgttgtgg
     3061 tctaaatgac gaagtagcac atgcctttcc ccgtcattac attctgaaag aaggggattt
     3121 gcttaaagtt gacatggtac tcagtgagcc tttggataaa tcaattgttg atgtagcagc
     3181 tttagatttt gataatgtgc ctgagatgaa gaaatggaca agatcttata ctggtggttt
     3241 agctgactct tgttgggctt atgctgttgg aacaccgtct gacgaaataa agcaattaat
     3301 ggatgtcacc aaagaagcca tgtaccgtgg tattgaaaaa gcagtaattg gcaatcgtat
     3361 tggtgatatt ggcgcagctg ttcaagaata cgctgaaagc ttcggttatg gtgtcgtgcg
     3421 tgatcttgtt ggtcacggtg ttggtcctac aatgcatgaa gagccaatgg taccaaacta
     3481 tggaacagca ggtcgtggac ttcgtctaaa agaaggcatg gtcttgactg ttgagccaat
     3541 gattaataca ggaacttggg aaattgatac cgacatcaag acaggttggg ctcataaaac
     3601 cctagatggt ggtttatctt gccaatacga acaccaattt gtgattacta aagatggtcc
     3661 cgttatttta acaagtcaag gagaagaaag aacttactaa aatggcagaa aaaaaatggt
     3721 ttgataaggt actgtccaag tggcagtatg aacccattca agtctttatg aggcatttac
     3781 aaagtgcaga aatggattta tctgccattg cggttgcgta ttaccttatc ttaacggcct
     3841 ttccattaat tgttattgca gccaatattt ttccttacct caatattgat attgctgatt
     3901 tgttacgttt aatgaagcaa aatttgccta aagatatttt tagaccggct tctgcaattg
     3961 tagaaaatat tttctctaaa ccgtctggaa gtgttttggg agtagcgact ttgacaggat
     4021 tatggacaat gtctcgaagt ttgacatcgc tgcaaaaagc tattaataaa gcctatggcg
     4081 cttctcagca tcgagatttc tttatcggac acttggttgg tttgttgacc agtttaatta
     4141 ttttattttt attagccttt gccttaatct tttcaacatt ttctaaagct gctattcaag
     4201 tgctggataa gcattaccat ttgagtgata atatcacaac gattttctta ctcctcattc
     4261 aacctattac agttttgatt atttttgttg gcttgatgct actatatttt ttattaccca
     4321 atgttaagat taaaaaaatt cgctacattt taccaggaac cctatttaca tcttttgtga
     4381 tgacattttt gagtaatctg gttggcaatt acgttgtgta taatgttgag cggatggtag
     4441 atattaaaat gtttggttca gttatgattt ttatcatcat gctatggttt attttcttag
     4501 caagaatcct gattttagga gctatattta atgcgaccta tcaagaaatg tccttgggga
     4561 aattagaagg tcgtagtggt gatatgatcg ctatccttaa aaaaacactt gggaatgatt
     4621 cagatctatc tccttcacag tctatcgaag atagtcacac tgattgatac aaaaaagata
     4681 ataagtcgtg gagtgagaaa ctattttctt gcttcatttt ttatgaggat aaatagaaaa
     4741 tcattgatct tagcaaatag aaaggcagat aaaacggatg aaattgcgaa caaatgcagg
     4801 accattacag ggaacgattc aagttccagg agacaagtcc attagtcacc gggcagtcat
     4861 attaggagct gttgctaaag gggaaacacg agtaaaagga ctcttaaaag gagaagacgt
     4921 gctttccacg attcaagcct ttaggaattt gggggtccgt atcgaagaaa aagatgacca
     4981 gcttgtgata gaaggtcaag gttttcaagg attgaccgct ccttgtcaga cacttaatat
     5041 gggaaattct ggaacctcta tgcgcctcat tgctggctta ttggcaggtc aaccttttag
     5101 tgtcaaaatg attggcgatg aaagcttatc caaacgtcct atggatcgga ttgtttatcc
     5161 gttaaagcaa atgggggttg agatatctgg agaaacagat aggcaatttc ctccactaca
     5221 attgcaaggt aatcgtaatt tacaaccaat cacatatact ttgcctatct cttctgctca
     5281 ggttaagtca gctattttgt tagcagcttt gcaagcaaaa ggaacaacac aggttgttga
     5341 aaaagagatt actcgaaacc atacagaaga aatgattcaa caatttggtg gacgattgat
     5401 agttgatggt aaacgcatta ctttggtggg accccagcag ctcactgctc aagagataac
     5461 tgtccccgga gatatttcta gtgcagcttt ttggcttgtc gccggcttaa ttattcctgg
     5521 ttcggagctc cttttaaaga atgttggagt caatccgaca cgaacaggga ttcttgaagt
     5581 ggttgaaaaa atgggagcac agattgtcta tgaagatatg aataagaaag agcaagtaac
     5641 tagtattcga gtggtatatt ctcacttgaa aggaactatc atatcaggag gtcttatccc
     5701 tcgattgatt gatgaacttc ccatcattgc acttcttgca acccaagcac aaggaacaac
     5761 ctgtattaaa gatgctcaag aattacgagt caaagaaaca gatcgtattc aagtagtaac
     5821 tgatattctt aacagtatgg gagctaatat caaagcgaca gcagatggca tgattatcaa
     5881 aggccctacg gtactatatg gggctaacac aagtacctat ggagatcatc gtattggtat
     5941 gatgacagca attgcagcct tgcttgttaa acaaggacag gtccatttgg ataaagaaga
     6001 agccatcatg acgtcttatc caacgttttt caaagattta gaaaggctgt gtcatgacta
     6061 aagtgttatt gggatttatg ggagtgggga aaacaacggt ttcgaaacac ctaagtatgc
     6121 actgtaaaga tatggatgct attattgaag ctaaaatcgg tatgtctatt gcagcttttt
     6181 ttgaacagca tggagaaata gcatttcgaa caattgaaag tcaagtgtta aaagatctat
     6241 tgtttgcaaa tgataatagt atcatcgtaa caggtggcgg tgtagtggtt ttacaagaaa
     6301 atcgacaatt actgagaaaa aatcaccagc ataatatttt attggtagct tcttttgaaa
     6361 ctttgtacca gcgtttaaaa catgataaaa agtctcaaag acctctattt cttaagtact
     6421 ctaaggaagc attttatgaa ttttatcaac aacgtatggt attttatgag ggactttcag
     6481 atttagtaat cagagttgac catcgtacgc ctgaagaagt tgccaacatc attgagggtt
     6541 attagtaggt cattgtcgta atctgatatt tatggtttta aacaggtatc tgtctaaagc
     6601 acttcttatg gcaagttggc tttattaaat attaggaaat aatcttgatt attctataat
     6661 gattaaaatt ttgagaggac aatctggcta atataggtta taatggtagt attcgttaaa
     6721 agtgcaattg taatactaag agatgataag atatgacaaa ataccccatg ggtggcctta
     6781 gtcaccatga agaattacgt tatttttatc tcctaaggaa tttgagttac cttagtgaga
     6841 atgaaaaaaa agagtttgct tttttaaaat ctaaattgga aattggtcga gcttatgctc
     6901 cttctaagca gcattatagg aagtcaaaac ggcaagaacc ttactttgaa gatgactact
     6961 ataacgacta ctcaccaaat gatttactag aagatgatga cgtcaatcat gactcttctt
     7021 ttgttccata tggtttaccg atatatccta aagaagacag atatttaaac aaaaaaacaa
     7081 aacttacagc tcgtagacct atagatactc cgcagcctat tgatgaagac gatgcttttt
     7141 taacagagtc tgttgctcgt tgtgctcttc ctagatctca aaaaagaaag cataagaaaa
     7201 aaggatgtat gaaatggttt tttaacattc ttggcttatt gctaatgact gtgcttatgg
     7261 ggttagggtt gatgtttgca aaaggggttt ttgatatttc tactaataaa gctaattaca
     7321 aaccagctgt ttcccaagct tttgatggtc aagaaactca agatggtacg aacattctgg
     7381 ttttgggttc tgaccaacga gttactcaag gttctacaga tgctcgcaca gataccatta
     7441 tggttgtcaa tgtcggcaac catgctaaaa aaataaaaat ggtctctttt atgcgtgaca
     7501 ctttgattaa cattccagga tacagttata atgataattc gtatgatctt aaattaaata
     7561 gtgcatttaa tcttggagag caagaagatc accacggagc agagtacgtt cgacgggcct
     7621 taaaacataa ttttgatatc gacattaagt attatgtgat ggtagatttt gaaacatttg
     7681 cagaagctat tgacaccttg tttccaaatg gtgttaagat tgatgccaaa tttgcgacag
     7741 taggtggtgt agctgttgac tccgtagaag ttccagatga cctgcgaatg aaaaatgggg
     7801 ttgttcccaa ccaaaccatc gaagttggag aacaacgcat ggatggtaga accttgctca
     7861 actatgctcg tttccgtaaa gatgacgaag gagatttcgg acgaaccgtc cgtcagcaac
     7921 aggttatgtc agctgttatg tctcaaatca aagacccaac taaactcttt acagggtctg
     7981 cggctattgg taaaatctat gcgctgactt cgaccaatgt ttcttttcca tttgttgtta
     8041 aaaatggtgt ttctgtttta ggaagtggga aaaatggagt tgagcacgtg accatcccag
     8101 aaaacgggga ttgggttgac gaatacgata tgtatggagg acaagccctt tacatagatt
     8161 ttgataagta tcagaaaacg ttagccaaat taggtctgcg ctaagatatg gtataatgga
     8221 gagtaactaa agttgctctt cttttttgag caatggttag ccctagaaaa ggaaaaagaa
     8281 taagaatgtt gaaaaaaaat gatattatcc aagttgctat ttcagattta agccatgagg
     8341 gagcaggtgt cgctaaacac gatggttttg ttttctttgt tgataatgcc ttgccagaag
     8401 aagtgattga catgcgtgtc ttaaaggtca ataaaaacag cggttttggc aaagtagaag
     8461 cctatcatta cctgtcgcca gctagaaatg cagatgtcaa tttaacttat ttgcgaacag
     8521 gcattgcaga ccttggacat ctaacttatg aagaccaact gactttcaaa aagaaacaag
     8581 ttcaggacag cctctataaa attgctggaa tcagtgacgt gacagtcgaa agcacgattg
     8641 ggatgacaga acctttagct taccgaaata aggctcaggt tcctgttaga cgtgttaatg
     8701 gtcagctaga aacaggcttt ttccgcaagc attctcatga cttgattcct atttcggatt
     8761 attatattca ggacaaagag attgatcgtc tcattaattt tacccgtgat ttattacgcc
     8821 gctttgatat taaaccgtat gacgaaacag aacaaacagg tctcttgaga aatattgttg
     8881 ttcgccgagg ccattactct ggagaaatga tgctggtctt agtgactaca cgcccaaaag
     8941 ttttccgtgt tgaccaagtc attgaaaaaa tcgttgaagc ttttccagca gtggtgtcta
     9001 ttattcaaaa tattaatgat aagaacacca atgcaatctt tggtaaagat ttcaaaacgc
     9061 tttacggcaa ggataccatt actgatagca tgcttggaaa caactatgcc atttctgccc
     9121 agtctttcta ccaagtgaat acggttatgg cagaaaaact ctatcaaaca gctatagcct
     9181 tttcagacct ttctaaagat gacattgtga ttgacgccta ctcaggtatc ggaaccattg
     9241 gcctatcatt tgctaaaaca gttaaagctg tttatggtgt tgaagtgatt gaagcagctg
     9301 ttagagatgc tcaacacaat gccgctctta atggcatcac caatgcctac tttgtcgcag
     9361 ataccgcaga acatgccatg gcaacatggg cgaaagatgg cattaaacca agtgttattc
     9421 tggtagaccc gccacgaaaa ggcttaacag aaagtttcat ccaagccagc gtggcaatgg
     9481 gaccacaaaa aattacctac gtttcctgca acccagccac catggcgcgt gacatcaagc
     9541 gttatcaaga gttgggttac aaactggcca aagtacagcc cgtagatttg tttccccaga
     9601 cgcatcacgt ggagacggta gcacttttgt ccaaacttgg tgtcgataag catataaata
     9661 ttgaaattga gatggatgag cttgatttga caagtgctga aagtaaggca acatatgctc
     9721 aaatcaaaga atatgtttgg aataaatttg aattaaaagt ttcgacatta tatattgcac
     9781 agataaaaag gaaatgtgga atagaattac gagaacatta caacaagtct aaaaaggaga
     9841 aacaaattat tccacagtgt acacctgaaa aagaagaagc catcatggat gctttgagac
     9901 atttcaaaat gattgaatag aaaagaatga cagcatatca ctttctgcat ttattacatt
     9961 cctatttggt ataagaacaa ctattattct tttcttgcaa ggtatcaatt agaaaatagg
    10021 gtcaatataa agaatggtag gataatacct atatataaac catggaggta ggcatatgag
    10081 gtcttatgaa agtaaggaag aattaaagaa tgagataaag aaaacttttg aaaaatatat
    10141 ttcagagttt gacaatatac cagaagaact aaaagataaa agactagaag aagttgatag
    10201 gacaccagca gaaaatcttg cctatcaagt aggctggacg actttagtat taaaatggga
    10261 agaagatgag aaaaaaggta tagatgttaa aacaccatca gataaattca agtggaatca
    10321 acttggagaa ttatatcaat ggtttacaga tacctatgcc cataaatctc tatatgaact
    10381 aaaagaacaa ctaacagaaa atgtaaaaaa aatttatctt atgatagatg aattaacaga
    10441 tgaagaatta tttaaaccac atatgagaaa atgggcagat gaagcaacca aaactgctac
    10501 ttgggaagta tataaattta ttcatgtaaa tacagtagcg ccatttggaa catttaggac
    10561 taagattagg aaatggaaga aattagttct atatatagaa aagtataaat aagtttactt
    10621 aggaggattt tatggcagtt gcaaagatca aagttacatt aaattgccca atagaaaaag
    10681 tatgggataa agttactgac cttcgtgatt ttagttggag aagtgatatc aaagatatca
    10741 aaattattga tgataagaat tttgtagaga ttacaaaaga tgggatagaa acaaatttta
    10801 aagttataaa atgtacgaaa catcaatgct ggtcttttga aattgaaaac gcaaatataa
    10861 aaggaacttg gataggaaaa tt
//
LOCUS       DATWEK010000046        10826 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.046, whole genome shotgun sequence.
ACCESSION   DATWEK010000046 DATWEK010000000
VERSION     DATWEK010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10826
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.046"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            319..1926
                     /locus_tag="VCR92_001589"
     CDS             319..1926
                     /locus_tag="VCR92_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP4268641.1"
                     /translation="MHVSKLFTSQQWRELKLISYLTENSNAIGVKDKELSKALNISML
                     TLQSCLTNMQFMKEVGGITYKDGYINIWYHQCCGLQEVYQKALRESPSLKLLELLFFR
                     DFSSLEELAEELFVSLSTLKRLIKKTNTYLSHTFAISIVTSPVQVSGDERQIRLFYLK
                     YFSEAYKISEWPFGDILNLKNCERLLSLLIKEVDVKVHFTLFQHLKILSGVNLIRYYK
                     GYSCSYNNKKTSHRFSQLIQHSSEIQDLSRLFYLKFGLHLDEYTIAEMFSNHLNDKLE
                     IGCAFEIINQDPISGGRQVTNWIHLLDEMEIKLNLSITNKYEVAVTLHNASVLNEEDI
                     TANYLLFDYKKSYLNFYQKEHPRIYEAFVTSVEKLMQADNAQVSKELINQLTYCFFIT
                     WENSFLKVNQKEKVRLLVIERSYNSVGNFLKKYIGEFFSITNFDELDCLTIDLVEIEK
                     QYDVIVTDVMVGKSEELEIFFFYKMIPEAIIDRLNEFLNVSFTDNNVMVKNLEAPSPS
                     KSHSDKEVQKPEKPDNSVKQATSATSS"
     gene            2116..3165
                     /locus_tag="VCR92_001590"
     CDS             2116..3165
                     /locus_tag="VCR92_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407887.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEP4268642.1"
                     /translation="MSKRNPNKHYSLRKLKTGTASVAVALTVLGTGLANTTDVKAETE
                     HVDVVLSAKEANKVFEERKALEKQARDLGDTINHMSQTISEQSRKIAALKSEAELKNQ
                     QALEALNNKNEQIAKLTNENAQLKEAIEGYVQTIQNASREIAAKQQELAAAKSQLEAK
                     NAEIEALKQQDASKTEEIAKLQSEAATLENLLGSAKRELTDLQAKLDTANTEKEKLQS
                     QAAALEKQLEATKKELADLQAKLAATNQEKEKLEAEAKALKEQLAKQAEELAKLKADK
                     ASGAQKPDTKPGNKEVPTRPSQTRTNTNKAPMAQTKRQLPSTGEETTNPFFTAAAATV
                     IASAGVLALKRKEEN"
     gene            3390..4466
                     /locus_tag="VCR92_001591"
     CDS             3390..4466
                     /locus_tag="VCR92_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407885.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEP4268643.1"
                     /translation="MARKDTNKQYSLRKLKTGTASVAVAVAVLGAGFANQTEVKAAES
                     PKSTETSANGADKLADAYNTLLTEHEKLRDEYYTLIDAKEEEPRYKALRGENQDLREK
                     EGKYQDKIKKLEEKEKNLEKKSEDVERHYLKKLDQEHKEQEERQKNLEELERQSQREI
                     DKRYQEQLQKQQQLETEKQISEASRKSLSRDLEASRAAKKDLEAEHQKLKEEKQISDA
                     SRQGLSRDLEASREAKKKVEADLAEANSKLQALEKLNKELEEGKKLSEKEKAELQARL
                     EAEAKALKEQLAKQAEELAKLKGNQTPNAKVAPQANRSRSAMTQQKRTLPSTGEAANP
                     FFTAAAATVMVSAGMLALKRKEEN"
     gene            4677..5609
                     /locus_tag="VCR92_001592"
                     /pseudo
     CDS             4677..5609
                     /locus_tag="VCR92_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561044.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            5944..9390
                     /gene="scpA/B"
                     /locus_tag="VCR92_001593"
     CDS             5944..9390
                     /gene="scpA/B"
                     /locus_tag="VCR92_001593"
                     /EC_number="3.4.21.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C5a peptidase ScpA/B"
                     /protein_id="HEP4268644.1"
                     /translation="MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQA
                     VEPPQPTAVSEEAPSSSKETNPPQIPDDAEETVADKANDPAPQAPAKTADTPATSKAT
                     IRDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKA
                     KKEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEG
                     AMPEAQLLLMRVEIVNGLADYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDET
                     KKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSP
                     DKQLTETATVKTDDHQDKEMPVLSTNRFEPNKAYDYAYANRGTKEDDFKDVEGKIALI
                     ERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKDN
                     PQKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAK
                     LSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYF
                     SPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELY
                     YQATVQTDKVDGKHFALAPKALYETSWQKITIPANSSKQVTVPIDASRFSKDLLAQMK
                     NGYFLEGFVRFKQDPKKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSD
                     AKDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGT
                     FAKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGN
                     VVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPIS
                     SGAKEQHTDFDVIVDNTTPEVATSATFSTEDRRLTLASKPKTSQPIYRERIAYTYMDE
                     DLPTTEYISPNEDGTFTLPEEAETMEGGTVPLKMSDFTYVVEDMAGNITYTPVTKLLE
                     GHSNKPEQDGSDQAPDKKPETKPEQDGSGQTPNKKPETKPEKDSSGQTPGKTPQKGQP
                     SRALEKRSSKRALATKASTRDQLPTTNDKDTNRLHLLKLVMTTFFLGLVAHIFKTKRT
                     ED"
     gene            9487..10611
                     /gene="fbpA"
                     /locus_tag="VCR92_001594"
     CDS             9487..10611
                     /gene="fbpA"
                     /locus_tag="VCR92_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibronectin-binding protein FbpA"
                     /protein_id="HEP4268645.1"
                     /translation="MRRAENNKHSRYSIRKLSVGVTSIAIASLFLGKVAYAVDSMQPI
                     SSTQGNRANTSKKWYDINEYGLIPVDISFEAAKKDFKEEVEKSLLSEEQQKTYNQKIE
                     AARNKDDLLLTYHSEYSKDIKKHSTSTEPVEASVQETQASVSDSMVTDDSTSVTADSP
                     EKTPSTETPAPAQPAESEESSVAAPSEETPSPETPAAPETPEEPAAPSPSPESEEPSV
                     AASSEETPSPETPAAPETPEEPAAPAQPAESEESSVAATTSPSPSTPAESETQTPPAV
                     TKDSDKPSSAAEKPAASSLVSEQTVQQPTSKRSSDKKEEQEQSYSPNRSLSRQVRAHE
                     SGKYLPSTGEKAQPLFIATMTLMSLFGSLLVTKRQKETKK"
BASE COUNT         4005 a         2123 c         2106 g         2592 t
ORIGIN      
        1 tgagtgataa tcaagaaatg aagttcaaaa aatataaata aaataaaaca caagaactgc
       61 taaaagcagt gaatgacata aatgtcgcta aaaaaataga tagaagagtc taaaatttca
      121 gttttaggtc acgttttatg aatggaaatc agaatgatga ccttaagttg tgatttgcgc
      181 gtcattgacc gctttcttcg ttttaatgaa agaatttgaa agatatttta tggtatactt
      241 ttccttaata tggttcatac ggacttgata aatctattta caaaaataat aaaaaattaa
      301 gataaggaca tgaagttaat gcatgtaagt aaattgttta ctagccaaca atggagagaa
      361 ttgaaactga tctcatattt aacagaaaac tccaatgcta tcggagttaa agataaggag
      421 cttagcaagg ctctcaatat ttccatgtta acattacagt catgcctcac taatatgcag
      481 tttatgaaag aagtaggtgg aattacctac aaagacggct atattaacat ttggtatcac
      541 cagtgttgtg ggctacaaga ggtctatcaa aaagctcttc gagaatcgcc ttctttgaaa
      601 ttactggagc ttttgttttt cagagacttt agttccttag aagagttagc tgaagagctg
      661 tttgtcagct tatctaccct caaacgcctc atcaaaaaaa ccaacactta cttgtctcat
      721 acctttgcta ttagtatcgt gacaagtcca gtgcaggtgt caggagatga gaggcaaatt
      781 cgcctgtttt acctcaagta tttttcagaa gcctataaaa tctcagaatg gccatttggg
      841 gacattttaa acctgaaaaa ctgtgaacgc ctattgagct tattgatcaa agaagtagat
      901 gtcaaagttc attttacgct atttcagcac ttaaaaatct taagtggcgt caacttgatc
      961 cgttactaca aggggtattc ttgcagttat aacaataaaa aaaccagtca ccgtttttct
     1021 caacttatcc aacattcctc agaaatccag gatctttctc gcttgttcta cctcaaattt
     1081 gggttacatc tcgacgagta taccatagct gaaatgtttt ctaaccatct taacgacaag
     1141 ctagaaattg gctgtgcttt tgagattatc aatcaagacc caatatcagg aggcagacaa
     1201 gtaaccaact ggatccatct attagatgag atggaaatca agctcaatct cagcatcacc
     1261 aataaatacg aagttgccgt aaccctccat aacgcttcgg tgttaaacga agaagacatt
     1321 acagccaatt atttgctgtt tgattataaa aagagttacc tgaactttta ccaaaaagaa
     1381 caccctcgta tctatgaggc ctttgtgaca agtgtcgaga agctgatgca ggcagataat
     1441 gctcaagtta gcaaagaatt gatcaatcag ctcacttatt gtttctttat tacctgggaa
     1501 aatagtttct taaaagtaaa tcaaaaagaa aaagtacgac tcctagtgat agagagaagt
     1561 tacaatagtg tcggtaattt tttgaaaaag tacatcggtg agtttttcag cattactaat
     1621 tttgatgagt tagattgtct gacaattgat ctagtagaga ttgaaaaaca gtacgatgtt
     1681 atcgtgacag atgttatggt gggtaaaagc gaagagttag agattttctt tttctacaag
     1741 atgatcccag aagctattat tgatagatta aacgaatttt tgaacgttag tttcacagat
     1801 aacaatgtta tggtcaaaaa cctcgaagcc ccttctcctt caaaatctca tagcgacaaa
     1861 gaggtacaaa agccagaaaa gccagacaat tctgttaaac aagcaacatc agcaacatca
     1921 tcataggatt tcagacgtca tggtaagaaa aaaagaatca tttacagccc atagaggtaa
     1981 ggtcaaaagc tgaaaacagc tcaaaaaaac tgacctttac cttttggctt tttttattta
     2041 gaataatttt attggagaga tgcttaatct aatttaagca caattcttag aaagttaaga
     2101 aataaggagt aaacaatgtc taaaagaaat ccaaacaaac actactcact gagaaagtta
     2161 aaaacaggta ctgcatcagt agcagtagct ttgacagttt tggggactgg attagcaaac
     2221 acaactgatg taaaggctga gactgagcat gttgatgttg tgctttcagc aaaagaagct
     2281 aacaaagtat tcgaagagcg caaagccttg gaaaaacaag cgcgtgattt gggtgacact
     2341 attaatcaca tgtcacaaac cattagtgag caaagccgca agattgcagc attaaagtct
     2401 gaagcagaac ttaaaaacca acaagctctt gaagctttaa ataataaaaa tgagcagatt
     2461 gctaaattaa ccaacgaaaa cgcacagtta aaagaagcca ttgaaggtta tgtgcaaact
     2521 atccaaaacg ctagccgtga aatcgcagca aaacaacaag aacttgcagc tgcaaaaagc
     2581 cagttagagg caaaaaatgc tgagattgag gcattgaaac aacaagatgc ctctaagact
     2641 gaggaaattg ctaaattgca atcagaagca gcaactttag aaaacctcct aggttcagct
     2701 aagcgtgaat tgactgatct gcaagctaag ctagatacag ctaacactga aaaagaaaag
     2761 ctccaatcac aagcagcagc cctagaaaaa caactagaag caactaaaaa agagttagct
     2821 gatttacagg ctaaattagc agcaaccaac caagaaaaag aaaagttaga agctgaagca
     2881 aaagctctta aagagcaatt agcaaaacaa gctgaagagc ttgctaagct aaaagcagat
     2941 aaagcttcag gagctcaaaa accagatact aaacctggca ataaagaggt tccaacaaga
     3001 ccgtcacaaa caagaacaaa cactaataaa gctcctatgg cgcaaacaaa gagacaatta
     3061 ccgtcaacag gcgaagaaac aaccaaccca ttcttcactg cagcagctgc aacagtgatc
     3121 gcatctgcag gcgtacttgc cctaaaacgc aaagaagaaa actaagccca atccacacta
     3181 tcttttctag cccaagaaaa aaacaaaaaa agaggaagac cattcctctt tttttgaacg
     3241 gttaaacagc aaaaaggtca aaaaggtact aaagtctcaa aaacctggtc tttacctttt
     3301 accgcttatt ctttagaata gaattattag agagaagtct tagaaaaatg aggctaattc
     3361 cctaaagatg aaaaaataag gagcaaataa tggctagaaa agatacgaat aaacagtatt
     3421 cgcttagaaa attaaaaaca ggtacagcat ccgtagcggt cgctgtggct gttttaggag
     3481 caggctttgc aaaccaaaca gaagttaagg ctgcggagtc tccaaaaagt actgagactt
     3541 ctgctaatgg agctgataaa ttagctgatg catacaacac attgcttact gaacatgaga
     3601 aactcagaga tgagtattat acattaattg atgctaaaga agaagaacct aggtataaag
     3661 cattgagagg cgaaaatcaa gatcttcggg aaaaagaagg aaaataccag gataaaataa
     3721 aaaaattaga agaaaaagag aaaaatttag aaaaaaaatc agaagatgta gaacgtcact
     3781 atcttaaaaa actagatcaa gaacataaag aacaagaaga acgtcaaaaa aatctagaag
     3841 aactcgaacg tcaaagtcaa cgagaaatag acaagcgtta tcaagaacaa ctccaaaaac
     3901 aacaacaatt agaaacagaa aagcaaatct cagaagctag tcgtaagagc ttaagccgtg
     3961 accttgaagc gtctcgtgca gctaaaaaag accttgaagc tgagcaccaa aaactcaaag
     4021 aggaaaaaca aatctcagac gcaagccgtc aaggcctaag ccgtgacctt gaagcgtctc
     4081 gcgaagctaa gaaaaaagta gaagcagact tagcagaagc aaatagcaaa cttcaagccc
     4141 ttgaaaaact aaacaaagag cttgaagaag gtaagaaatt atcagaaaaa gaaaaagctg
     4201 agttacaagc aagactagaa gctgaagcaa aagctcttaa agagcaattg gctaaacaag
     4261 ctgaagaact tgctaaacta aaaggcaacc aaacaccaaa cgctaaagta gccccacaag
     4321 ctaaccgttc tagatcagca atgacgcaac aaaagagaac gttaccgtca acaggcgaag
     4381 cagctaaccc attctttaca gcagcagctg caacagtaat ggtatctgca ggtatgcttg
     4441 ctctaaaacg caaagaagaa aactaagcta ttagactgat gctaaagtta agagagaatc
     4501 aaatgattct ctctttttga gtggctaagt aactaacaat ctcaattaga ccaaaaaatg
     4561 ggaatggttc aaaaagctgg cctttactcc ttttgattaa ccatatataa gtaaaaacat
     4621 taggaaaata atagtaatat taagtttgtt tcctcaataa aatcaaggag tagataatgg
     4681 ctagacaaca aaccaagaaa aattattcac tacggaaact aaaaaccggt acggcttgag
     4741 tagccgttgc tttgaccgtt ttgggtgcag gttttgcaaa ccaaacggaa gtaagagctg
     4801 aaggggtaaa cccgactacg aacttgccag agaaggctaa atatgccgca ttgaaagatg
     4861 agaatactgg tttacgtggt gatcagaaaa aattagtaaa aaaacttgaa gaagaacaag
     4921 agaagagcaa aaatctagaa aagcaaaaac aggagttaga aaaccaagcc cttaactttc
     4981 aagacgtaat tgaaactcag gaaaaagaag atctcaaaac aactttagct aagactacta
     5041 aagaaaatga gatttcagaa gctagccgta aagggttaag ccgagactta gaagcttctc
     5101 gtgcagctaa aaaagagcta gaagctaagc accaaaaatt agcagaagaa catcaagttt
     5161 cagagactag ccgtaagggt ctaagccgtg accttgaagc atcacgtgaa gctaataaga
     5221 aggttacatc tgagttaaca caagcaaaag ctcaactctc agcgcttgaa gaaagtaaga
     5281 aattatcaga aaaagaaaaa gctgagttac aagcaaaact agatgcacaa ggaaaagccc
     5341 tcaaagaaca attagcaaaa caaactgaag agcttgcaaa actaagagct gaaaaagcgg
     5401 caggttcaaa aacacctgct accaaaccag ctaataaaga aagatcaggt agagctgctc
     5461 aaacagctac aagacctagc caaaataaag gaatgagatc acaattaccg tcaacaggcg
     5521 aagcagctaa cccattcttt acagcagcag ctgcaacagt gatggtatct gcaggtatgc
     5581 ttgctctaaa acgcaaagaa gaaaactaag cctttagaac ttggtttttg taacggtgca
     5641 atagacaaaa gtaagcaagg ccaaaaactg agaaagtcct aaaaagctgg cctttacccc
     5701 tcaaaattaa tgttttataa taaagatgtt agtaatataa ttgataaatg agatacattt
     5761 aatcattatg gcaaaagcaa gaaaaatagc tgtatcatat gcaaataacc cctgtttgct
     5821 ctttaaaaaa gacgttatcc ttatttctcc acgcacagat ggacagctag gagagaatcg
     5881 tttgattctc tcttttctta atggtcataa agacaaagtc tctcatcatg aaaggacgac
     5941 acattgcgta aaaaacaaaa attaccattt gataaacttg ccattgcgct catgtctacg
     6001 agcatcttgc tcaatgcaca atcagacatt aaagcaaata ctgtgacaga agacactcct
     6061 gctaccgaac aagccgtaga acccccacaa ccaacagcgg tttctgagga agcaccatca
     6121 tcatcaaagg aaactaaccc tccacaaatt cctgatgacg cagaagaaac agtagcagat
     6181 aaggctaatg atccagcccc tcaagctcct gctaaaactg ctgatacacc agcaacctca
     6241 aaagcgacta ttagggattt gaacgaccct tctcaggtca aaaccctgca ggaaaaagca
     6301 ggcaagggag ctgggactgt tgttgcagtg attgatgctg gttttgataa aaatcatgaa
     6361 gcgtggcgtt taacagacaa aaccaaagca cgttaccaat caaaagaaga tcttgaaaaa
     6421 gctaaaaaag agcacggtat tacctacggc gagtgggtca atgataaggt tgcttattac
     6481 cacgactata gcaaagatgg taaaaccgct gtcgatcaag agcacggcac acacgtgtca
     6541 gggatcttgt cagggaatgc tccatctgaa acgaaagaac cttaccgcct agaaggtgcg
     6601 atgcctgagg ctcaattgct tttgatgcgt gtcgaaattg taaatggact agcagactat
     6661 gctcgtaact acgctcaagc tatcagagat gctgtcaact tgggagctaa ggtgattaat
     6721 atgagctttg gtaatgctgc actagcttac gccaaccttc cagacgaaac caaaaaagct
     6781 tttgattatg ccaaatcaaa aggtgttagc attgtgacct cagctggtaa tgatagtagt
     6841 tttgggggca aaacccgtct acctctagca gatcatcctg attatggggt ggttgggaca
     6901 cctgcagcgg cagattcaac attgacagtt gcttcttaca gcccagataa acagctcact
     6961 gaaactgcta cggtcaaaac agacgatcat caagataaag aaatgcctgt tctttcaaca
     7021 aaccgttttg agccaaacaa ggcttacgac tatgcttatg ctaatcgtgg tacgaaagag
     7081 gatgatttta aggatgtcga aggtaagatt gcccttattg aacgtggcga tattgatttc
     7141 aaagataaga ttgcaaacgc taaaaaagct ggtgctgtag gggtcttgat ctatgacaat
     7201 caggacaagg gcttcccgat tgaattgcca aatgttgatc agatgcctgc ggcctttatc
     7261 agtcgaaaag acggtctctt attaaaagac aatccccaaa aaaccatcac cttcaatgcg
     7321 acacctaagg tattgccaac agcaagtggc accaaactaa gccgcttctc aagctggggt
     7381 ctgacagctg acggcaatat taagccagat attgcagcac ccggccaaga tattttgtcg
     7441 tcagtggcta acaacaagta tgccaaactt tctggaacta gtatgtctgc gccattggta
     7501 gcgggtatca tgggactatt gcaaaagcaa tatgagacac agtatcctga tatgacacca
     7561 tcagagcgtc ttgatttagc taaaaaagta ttgatgagct cagcaactgc cttatatgat
     7621 gaagatgaaa aagcttattt ttctcctcgc caacaaggag caggagcagt cgatgctaaa
     7681 aaagcttcag cagcaacgat gtatgtgaca gataaggata atacctcaag caaggttcac
     7741 ctgaacaatg tttctgataa atttgaagta acagtaacag ttcacaacaa atctgataaa
     7801 cctcaagagt tgtattacca agcaactgtt caaacagata aagtagatgg aaaacacttt
     7861 gccttggctc ctaaagcatt gtatgagaca tcatggcaaa aaatcacaat tccagccaat
     7921 agcagcaaac aagtcaccgt tccaatcgat gctagtcgat ttagcaagga cttgcttgcc
     7981 caaatgaaaa atggctattt cttagaaggt tttgttcgtt tcaaacaaga tcctaaaaaa
     8041 gaagagctta tgagcattcc atatattggt ttccgaggtg attttggcaa tctgtcagcc
     8101 ttagaaaaac caatctatga tagcaaagac ggtagcagct actatcatga agcaaatagt
     8161 gatgccaaag accaattaga tggtgatgga ttacagtttt acgctctgaa aaacaacttt
     8221 acagcactta ccacagagtc taacccatgg acgattatta aagctgtcaa agaaggggtt
     8281 gaaaacatag aggatatcga atcttcagag atcacagaaa ccatttttgc aggtactttt
     8341 gcaaaacaag acgatgatag ccactactat atccaccgtc acgctaatgg caagccatat
     8401 gctgcgatct ctccaaatgg ggacggtaac agagattatg tccaattcca aggtactttc
     8461 ttgcgtaatg ctaaaaacct tgtggctgaa gtcttggaca aagaaggaaa tgttgtttgg
     8521 acaagtgagg taaccgagca agttgttaaa aactacaaca atgacttggc aagcacactt
     8581 ggttcaaccc gttttgaaaa aacgcgttgg gacggtaaag ataaagacgg caaagttgtt
     8641 gctaacggaa cctacaccta tcgtgttcgc tacactccga ttagctcagg tgcaaaagaa
     8701 caacacactg attttgatgt gattgtagac aatacgacac ctgaagtcgc aacatcggca
     8761 acattctcaa cagaagatcg tcgtttgaca cttgcatcta aaccaaaaac cagccaaccg
     8821 atttaccgtg agcgtattgc ttacacttat atggatgagg atctgccaac aacagagtat
     8881 atttctccaa atgaagatgg tacctttact cttcctgaag aggctgaaac aatggaaggc
     8941 ggtactgttc cattgaaaat gtcagacttt acttatgttg ttgaagatat ggctggtaac
     9001 atcacttata caccagtgac taagctattg gagggtcact ctaataagcc agaacaagat
     9061 ggttcagatc aagcaccaga caaaaaacca gaaactaaac cagaacaaga cggttcaggt
     9121 caaacaccaa ataaaaaacc agaaactaaa ccagaaaaag atagttcagg tcaaacacca
     9181 ggtaaaactc ctcaaaaagg tcaaccttct cgtgctctag agaaacgatc ttctaagcgt
     9241 gctttagcta caaaagcatc aacaagagat cagttaccaa cgactaatga caaggataca
     9301 aatcgtttac atctccttaa gttagttatg accactttct tcttgggatt agtagctcat
     9361 atctttaaaa caaaacgcac tgaagattag tacaactgat cagatggcta ctattgatga
     9421 tgagttagat cagtcttctt ttcaaaagaa ggcatagcag tataaaaata gatatgtgag
     9481 gacaatatgc gtagagcaga aaataacaaa cacagccgct attccattcg caaactgagc
     9541 gttggggtaa cgagtatagc aattgcgagt ctctttttgg gaaaagttgc ctatgccgta
     9601 gatagcatgc agccaatctc ttcgactcaa ggaaacagag ccaatacatc caaaaaatgg
     9661 tatgatatta atgagtatgg tcttattcct gtagatataa gctttgaagc tgccaaaaaa
     9721 gattttaaag aagaagtaga aaaatcactt ttgtctgaag aacaacagaa aacgtataat
     9781 caaaaaattg aagctgcaag aaacaaagac gacctattgt taacgtatca tagtgagtac
     9841 tctaaagata ttaagaaaca ctcaacgtct actgagccag ttgaggcatc tgtgcaggag
     9901 acacaggcat cagtttcaga ttcgatggtg acagatgatt caacatcagt tacggctgat
     9961 tctcctgaga aaacaccatc tacagaaaca ccggctccag ctcaaccagc tgagagtgag
    10021 gagtcttcag tagcagctcc ttctgaggaa accccatctc cagaaactcc agcggcccca
    10081 gaaactcctg aagagccagc agctccatct ccatcacctg agagtgagga accttcagta
    10141 gcagcttctt ctgaggaaac cccatctcca gaaactccag cggctccaga aactcctgaa
    10201 gaaccagcag ctccagctca accagctgag agtgaagaat cttcagtagc agctacgaca
    10261 agcccgtctc catcaactcc agccgaatca gagactcaga cgccaccagc tgttactaaa
    10321 gactctgata agccatcttc agcagctgaa aaaccagcag cctcttcact tgtttcagaa
    10381 caaaccgttc aacaaccaac ttcaaagaga tcttctgata aaaaagaaga gcaagaacag
    10441 tcttactctc caaatcgctc attgtcaaga caggttaggg cccatgagtc aggtaagtac
    10501 ttgccttcaa caggtgaaaa agcacagcca ctctttatag ctactatgac tttgatgtct
    10561 ctatttggca gtcttttagt cacaaaacgc caaaaagaaa ctaaaaaata gtattactta
    10621 aactgaatag tattacttaa actgataaga gcttatttaa tagagagaac caatttggtt
    10681 ctctctattt ttttagatgt gctgcctcat caaaaagaag ttaggacaaa tagctgtcaa
    10741 caattgtctt ttgcttatct cttcagttgc tgtgatttta tcatatattg ataaaagatg
    10801 gcacgccaaa cgcatgaaga aacttt
//
LOCUS       DATWEK010000047        10658 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.047, whole genome shotgun sequence.
ACCESSION   DATWEK010000047 DATWEK010000000
VERSION     DATWEK010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10658
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.047"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            90..611
                     /locus_tag="VCR92_001595"
     CDS             90..611
                     /locus_tag="VCR92_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEP4268646.1"
                     /translation="MTKDRQIKKTKTAIYSAFLALLQKKEYSKITVRDMITLANVGRS
                     TFYAHYESKEMLLKELCEELFHHLFRQKRNVTFEDYLVHILKHFEQNKDSIATLLLSN
                     DPYFLLRFKNELEHDVYPNLRCKYIDKTTIPEVFLKQFVLSSFIETLKWWLHQRQRMS
                     ANELLKYYLELIK"
     gene            826..1344
                     /gene="rimM"
                     /locus_tag="VCR92_001596"
     CDS             826..1344
                     /gene="rimM"
                     /locus_tag="VCR92_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEP4268647.1"
                     /translation="MEYFNVGKIVNTQGLQGEMRVLSVSDFAEERFKKGSQLALFDDK
                     DQFVQEVTIVSHRKQKHFDIIKLKDMYHINAIEKYKGYTLKVSKANQGDLQEGEFYYH
                     QIIGMAVYEKDRLIGYVKEILQPGANDVWVVKRQGKRDLLLPYIPPVVLNVDVPNKRV
                     DVELMEGLDDED"
     gene            1334..2065
                     /gene="trmD"
                     /locus_tag="VCR92_001597"
     CDS             1334..2065
                     /gene="trmD"
                     /locus_tag="VCR92_001597"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEP4268648.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDYAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTIEQIEAKKPRIILLDPAGKPFTQAYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMVDATVRLIPQVLGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMTVPDVLMSGHHERIRLWRLEESLRKTYLRRPDLL
                     ERYDFSEEERKLLDKIKEALGQGED"
     gene            2065..3057
                     /locus_tag="VCR92_001598"
     CDS             2065..3057
                     /locus_tag="VCR92_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEP4268649.1"
                     /translation="MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQP
                     AILYPEKMIYDIPAYPSLTGVELTENLIKQLNRFEDRITICLKEEVLTFDKVKGGFSI
                     RTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICG
                     GGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLTTSTVNLLTPYVPKALKGIG
                     NLAEKLVIQKVKEDEVLELELDSLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTS
                     QEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDNRVVHSTSLID"
     gene            3236..4294
                     /locus_tag="VCR92_001599"
     CDS             3236..4294
                     /locus_tag="VCR92_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEP4268650.1"
                     /translation="MTTTDKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     MAAAEFLHIVQVFQFFTPIMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLRGIGDLINMMITASLAVLAVKYFGNKFGSLTIILLPITIGTGVGYIGWK
                     FLPYVSYVTTLIGQGINSFTTLQPILMSILIAVAFSLIIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTAAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKHPIMAIPMVFTAA
                     ISSLTVPLFNLVGTPASSGFGLVGAVGPIASLAGGSSILIIILAWIIVPFAVAFAAHK
                     VSKDILKLYKEDIFVFEG"
     gene            4307..5230
                     /locus_tag="VCR92_001600"
     CDS             4307..5230
                     /locus_tag="VCR92_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEP4268651.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGL
                     VVTGDVEETVKLPIMKPTEATQEADLIILFTKAMQLPQMLQDIKGIIGKETKVLCLLN
                     GLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMDPNNQDAGHQV
                     ADLLNKANLNATYDENVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLKMVKEI
                     IHEFVIVGQAEGVELNEEEITQYVMDTSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGINTPYCRMITELVHAKEAVLNIQ"
     gene            5486..6199
                     /locus_tag="VCR92_001601"
     CDS             5486..6199
                     /locus_tag="VCR92_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEP4268652.1"
                     /translation="MAKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHG
                     GAELFHSLQEELSNQEKSVKNSHIKKTIAQRASQFIYDNDVIFIDAGTTTEFLLPFLQ
                     AKNLTVVTNSIHHAARLVELSIETIIVGGYVKQTTDASIGNVALEQIRQMNFDKAFLG
                     MNGIDDSYLTTPDMEEAVIKKAVLSNAKLAYILVDGTKIGQVSFVKVAPINDVTIITL
                     GGSASILKQIKEKAKVIEL"
     gene            6196..7107
                     /gene="pfkB"
                     /locus_tag="VCR92_001602"
     CDS             6196..7107
                     /gene="pfkB"
                     /locus_tag="VCR92_001602"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEP4268653.1"
                     /translation="MIYTVTLNPSIDFIVRIDQINLGSVNRMASDDKFAGGKGINVSR
                     ILQRLDIASTATGFLGGFTGRFIEESLSAEGVKTDFVKGDQDTRINVKIKSQEETEIN
                     GQGPVISREQLEDLKTKLSQLTAEDTVVFAGSAPANLGNAVYKELFPLVRQSGAQVVC
                     DFEGQTLIDALTYNPLLVKPNNHELEAIFGTILTSLDDVETYARRLLEMGAQNVIISM
                     AGDGALLVTKEATYFAKPIKGEVKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACG
                     TATAFSDDLATIAFIKETYHKVEVEKR"
     gene            7104..9050
                     /locus_tag="VCR92_001603"
     CDS             7104..9050
                     /locus_tag="VCR92_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEP4268654.1"
                     /translation="MKIQDLLRKDIMILDLQAISKEVAIDEMITKLVEKDIVHDFDVF
                     KKSIMTREEQTSTGLGDGIAMPHSKNIVVDKPAVLFAKSNKGVDYKALDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADKLRAAATPEAVIAVFDEASTAKEEVVAPT
                     SGQDFIVAVTACPTGIAHTYMAEEALKKQAAEMGVAIKVETNGASGVANRLTAEDIQR
                     AKGVIVAADKAVEMDRFDGKQFIARPVADGIKKSQELISLILNNEGNTYHAKNGKSET
                     AVSTEKTSLGGAFYKHLMGGVSQMLPFVIGGGIMIALAFLLDNMLGVPNDQLGSLGSY
                     HEIAAIFMNIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASNGLAFGKVPFA
                     AGGEVSLGLTGVPSGFLGALVGGFLAGGVILALRKLLAGLPRSLEGVKSILLYPLLGV
                     LVTGFLMLFVNIPMAAINTALNDFLQGLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVANGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIVMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGIKLMAPHGGIFVIALTSNPI
                     LYLVFVVIGALVSGILFGALRKKA"
     gene            9143..9742
                     /locus_tag="VCR92_001604"
     CDS             9143..9742
                     /locus_tag="VCR92_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEP4268655.1"
                     /translation="MKVKKRRRRAKSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYA
                     DHETLTFVRKISHAAQSVAQKKQLYSSVMMAQAILESNNGKSQLSQKPYYNFFGIKGS
                     YKERSVIFPTLEDDGQGNLYQIDAAFRSYGSLTACFLDYARVLNDPLYDKTHKKFWSH
                     YQDATATLTGTYATDTTYNTKLNELIEWYQLTNFDGLMK"
     gene            9894..10601
                     /locus_tag="VCR92_001605"
     CDS             9894..10601
                     /locus_tag="VCR92_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEP4268656.1"
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSS
                     TRHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNG
                     SSVTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQD
                     ATAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYT
                     DAETLAVDEAWAKRMTY"
BASE COUNT         3302 a         1747 c         2293 g         3316 t
ORIGIN      
        1 tattctatta tctaaaagtt aaaatacaat tactataacc aaaaatgagc acctgttcaa
       61 tagtgaacaa catttagaaa gtgtccgata tgacaaaaga cagacaaatc aaaaaaacaa
      121 aaacagctat ctatagtgct tttcttgctt tattacaaaa aaaagaatat tcgaaaataa
      181 ctgttcgaga tatgattaca cttgctaatg tagggagatc aaccttttat gcacattatg
      241 aaagcaaaga aatgttacta aaagaactct gtgaagaact ttttcatcat ttgtttaggc
      301 aaaaaagaaa tgtgactttt gaggactatt tggtacatat tttaaagcat tttgaacaaa
      361 ataaagacag cattgcgacg ttgttacttt ctaatgatcc ctatttttta ttaagattta
      421 aaaacgaact agaacatgat gtttacccta acttgcgctg caagtatatc gacaaaacga
      481 ctattccaga agtattcctg aaacaatttg ttctatctag ttttatagaa accttaaaat
      541 ggtggctcca tcaaaggcaa aggatgtctg caaatgaact attaaagtat tatttagagc
      601 tcataaaata atgactagtg agtcatcttg ccaaattcaa ttttttaata cagacggatt
      661 ttaacaattt aacagagaaa gacaaaactg taagtgcaaa atagactata acgtgataaa
      721 ataataggta atttggttct gaaaaagaag tgtctatcaa actttagaat caagagaggt
      781 cgctaaagtg acgtgagata aagagttaac gatttaggag ctaccatgga atattttaat
      841 gttggaaaaa ttgtcaacac gcaaggcctg caaggagaga tgcgcgtgtt gtctgtcagt
      901 gattttgctg aggagcgctt taagaaggga tcgcaattgg ctttgtttga tgacaaagac
      961 cagtttgttc aagaagtgac aattgttagt caccgtaaac aaaagcattt tgatattatc
     1021 aaattgaaag acatgtatca tattaatgcg attgaaaaat ataagggcta tacgttaaaa
     1081 gtgtcaaaag ctaatcaagg agacctgcaa gaaggagaat tttactacca tcagattatc
     1141 ggtatggctg tttatgaaaa ggaccggttg attggctatg tcaaggaaat cttgcagcca
     1201 ggtgctaatg atgtttgggt agtgaaacgc caaggaaaac gagacttgct cttaccatat
     1261 attcccccag tagttcttaa cgtagatgtt cctaacaagc gcgtagatgt tgaattgatg
     1321 gaaggcttag acgatgaaga ttgatatttt aacccttttt cctgaaatgt ttgcccccct
     1381 agaacattcc attgtaggca aagcaaaaga aaaaggatta cttgacattc actaccataa
     1441 ctttcgagat tatgctgaaa aagctcgtca tgtggatgac gaaccctatg gtgggggcca
     1501 aggcatgtta ttgagagcac agcccatttt tgacaccatt gaacagattg aagccaaaaa
     1561 accaaggatt attcttttag atccagcagg taaacccttt actcaggctt atgctgaaga
     1621 attagctctt gaggaagagt taatttttat ttgtggtcat tatgaaggtt atgatgagcg
     1681 gattaagacc ttggtgacgg atgaaatttc attaggtgac tttgtattaa caggaggtga
     1741 gttggcggcc atgactatgg tggatgcgac tgtcaggtta attccacagg tacttgggaa
     1801 agaaagtagc catcaggacg attctttttc atcaggactt ttagaatacc ctcaatacac
     1861 aagaccttat gattatcgtg gtatgacagt tccagatgtt ctaatgagtg gtcatcacga
     1921 acgtattcgc ttgtggcgtc tagaagaaag tctcagaaaa acctatttga gaaggccaga
     1981 tttgttagag cggtacgatt tttccgagga agagcgcaag ctattggata agattaaaga
     2041 agcattgggt caaggagaag attagtgaaa gataaagcat atgatattac gattattggt
     2101 ggtggtccaa taggtttatt tgcagccttt tatgcaggtc ttaggggcgt aacagtaaag
     2161 attattgaga gtttgtcaga acttggtgga cagcctgcca ttctttatcc tgagaaaatg
     2221 atttatgata ttccagctta tccatcttta acaggtgttg agttgacaga aaatttaata
     2281 aaacaattaa accgttttga agatcgtata accatttgtt taaaagaaga agtattaacc
     2341 tttgacaagg ttaaaggtgg tttttcgatt aggactaata aggcagagca tttttcaaaa
     2401 gccattatca ttgcttgtgg aaatggcgct tttgcaccaa gaactttagg gttagaaagt
     2461 gaggaaaact ttgctgatca taaccttttt tataatgttc accagttgga ccagtttgcg
     2521 ggacaaaaag ttgtgatttg tggtggtgga gattcagcag ttgattgggc tttggcttta
     2581 gaagatattg ctgagagtgt gacggttgtg caccgtcgtg atgctttcag agcacatgaa
     2641 cacagtgtgg aattattgac aacatcaacg gtaaacctct taacacctta tgtgccaaaa
     2701 gcattgaaag gaattggaaa cctggctgaa aaattagtta ttcaaaaagt gaaagaagat
     2761 gaagtgttag aacttgaatt ggacagtctt attgttagtt ttggtttttc aacttctaat
     2821 aagaatttga aaaattggaa tctcgactat aagcgttcaa gtattactgt ttcaccactt
     2881 tttcaaacaa gtcaagaagg tatttttgcc attggtgatg cagccgctta taatgggaaa
     2941 gtggatttga ttgctactgg ttttggcgaa gcaccaacag cagttaatca ggccattaac
     3001 tatatttatc cagatcgaga taaccgtgtg gtgcattcaa cctctttaat tgactaaggg
     3061 agtcggaagt ttcaagagca gtagcaacag ctaatattca gtttgtcagg agaggacaaa
     3121 tggtttttta cctaagtctt cgtgacaagt tttatacttt gtgataaaat agtcattgtg
     3181 aaaaaagtgt gatggttttc acagattaac acattacaat gaaaaggggt ctatcatgac
     3241 aacaacagat aaagagacat ttagttcttt tatgaataag gtcttggctg gtacagcgat
     3301 tgctatcgtt gtggcactca ttccaaatgc tattttagcg actttcttaa aaccgctttt
     3361 gccaaacatg gcagctgctg aatttttaca cattgtgcaa gtcttccaat tcttcacgcc
     3421 gattatggct ggtttcttga ttgggcaaca atttaagttt aatcctatgc aacagttggc
     3481 tgttggtgga gctgcttata tcggttctgg ggcttgggct tatacagaag tcattcaaaa
     3541 aggtgtggcg acaggaacat tccaacttag aggtattggg gacttaatca atatgatgat
     3601 tacagctagc cttgcggttt tagctgtgaa atattttggg aataaatttg gctctttaac
     3661 cattatcttg ttacctatca ctataggaac tggcgtaggt tatattggtt ggaaattttt
     3721 gccttatgtg tcttacgtga caaccctgat cggacaaggt attaattctt ttacaacctt
     3781 acaacctatt ttaatgtcta ttttaattgc agttgctttc tcgcttatca ttgttagtcc
     3841 gatttcaact gttgcaatcg gtttagctat tgggcttaat ggaatggctg cgggagcagc
     3901 ttctatggga attgcatcga cagcagcagt cttagtgtgg gcgacgctta aagttaataa
     3961 atctggtgta ccaattgcta tcgcacttgg ggctatgaaa atgatgatgc caaacttctt
     4021 gaaacatcct atcatggcta ttccgatggt gttcactgca gcaattagct cattaacagt
     4081 accattgttt aatcttgttg gaacaccagc ttcatctggt tttggcttag ttggtgcagt
     4141 aggtccgatt gcttctttag caggtggtag ctcaatactt attattatcc ttgcttggat
     4201 cattgttccg tttgcggttg cttttgcggc gcataaggtt tctaaagata ttctaaaact
     4261 ttataaagaa gacattttcg tctttgaagg ctaataggag gaaaatatgt tagtttatat
     4321 tgctggctca ggagccatgg ggtgccgttt tggttaccaa atttcaaaaa caaataacga
     4381 tgtgattttg ttagataact gggaagatca tatcaatgcc attaaagaaa acggtttagt
     4441 ggtgacaggg gatgtggaag aaacagttaa gcttcctatt atgaaaccga ctgaagccac
     4501 tcaagaagcc gatttgatta tcttgtttac aaaagcaatg cagttgccac aaatgcttca
     4561 agacattaaa ggcattattg gaaaagaaac caaagtgctt tgccttttaa atggtcttgg
     4621 acacgaagac gttattcgtc agtacattcc agagcacaac attttgatgg gggtcactgt
     4681 ctggactgct ggtctagaag gaccaggtcg tgctcatctt caaggagttg gtgctcttaa
     4741 cttacaaagt atggatccaa acaatcaaga tgcgggacat caagtagctg acttgttaaa
     4801 taaagctaac ttaaatgcga cttatgatga gaatgttgtg ccaaacatct ggcgaaaagc
     4861 ttgcgtgaat ggtaccatga attcgacttg tgctctttta gattgtacga ttggcgaatt
     4921 atttgccagt gaagatggtc tcaaaatggt aaaagaaatc atccatgagt ttgttatcgt
     4981 tggtcaagca gaaggtgtcg aactaaacga agaagaaatc acacaatatg taatggatac
     5041 atctgttaaa gctgctcacc attacccatc aatgcaccaa gaccttgtgc aaaatcaccg
     5101 attgactgaa attgatttta tcaatggtgc agtcaatacc aaaggtgaaa agcttggtat
     5161 caatactcca tactgccgta tgattacaga actagttcac gctaaagaag cagtgttgaa
     5221 catccaataa acgctatcaa atcgttatac tcaatattat ggctaaagct ttaatattga
     5281 gttttttgtt atgctgatag tatttttctt aggcgtcatt atttgtgagc ctagattatg
     5341 agttaataaa agaaataata attggtagaa tttgatagat tttgaaaggt tatgcttgac
     5401 ttttagttat aaaatagtat aataattgta aacgatttca gttaggggtg gttctatctt
     5461 aaaatcaaaa cgaaaacaat taatcatggc aaagatcact gaagaaaact atgtttcttt
     5521 agaggattta atgcaattac tcaactcctc tgagtctact atccgtagag atctaggaga
     5581 gttggagcaa gaaggacggc tacatcgtgt tcatggaggt gctgaacttt ttcactcttt
     5641 acaagaggaa ctttctaacc aagaaaagtc tgtcaaaaac agtcatatta aaaaaactat
     5701 tgcgcaaaga gcctctcagt ttatctatga caacgatgtg atctttattg atgctgggac
     5761 aacgactgaa tttttattac cttttttaca agctaaaaat ttaactgtag ttactaattc
     5821 tattcatcat gctgctagat tagttgaact ctctattgag acgattattg taggtggtta
     5881 tgtcaaacaa acgaccgatg ccagtattgg taatgtagct ttggaacaga ttaggcagat
     5941 gaattttgac aaggcatttc ttggaatgaa tggtattgat gattcttacc tgacgactcc
     6001 tgatatggaa gaagcagtta ttaaaaaagc ggttctgtca aatgcaaaat tagcttacat
     6061 tttagtagat ggcactaaaa ttggtcaggt atcgtttgta aaagtagctc ctattaatga
     6121 tgtgactatt attacattag gaggatcagc aagtattctt aaacaaataa aggaaaaggc
     6181 aaaggtgatt gaattatgat ttataccgtg accttaaacc cttctattga ctttattgtc
     6241 agaattgacc aaataaatct tgggtcagtg aatcgcatgg cgagtgatga taagtttgct
     6301 ggaggtaaag gcattaatgt gagtcgcatc ttgcaacgtt tagacattgc tagcacggcg
     6361 acaggattct tgggtggttt tacaggacgt tttatcgaag aaagtttgag tgcagaaggc
     6421 gttaaaactg attttgtaaa aggtgatcaa gatactcgaa tcaatgttaa aatcaagtca
     6481 caagaagaga ctgaaataaa tggtcaagga cctgtcatta gtcgggaaca actagaggat
     6541 ttgaaaacta agctttccca gctaacagca gaggatacag ttgtctttgc aggttcagcg
     6601 ccagctaatc ttggcaatgc tgtttataag gaattatttc ctttagttag gcaaagcggt
     6661 gctcaggtgg tttgtgattt tgaaggacag actttaatag atgcgcttac atataatcct
     6721 ctgttggtta aacctaataa tcatgaacta gaagctattt ttggtacgat tctgactagt
     6781 cttgatgatg ttgaaaccta tgcccgtcgt cttttagaga tgggtgctca aaacgtcatc
     6841 atttcaatgg ctggtgatgg tgctttgctg gttactaaag aagcgactta ttttgctaaa
     6901 ccgattaagg gagaagttaa aaattctgtc ggtgctggtg attcgatggt tgctggcttt
     6961 acaggcgaat ttatgaagag tcaaaatcca atagaagcct taaaatgggg cgtggcttgt
     7021 ggtacagcga cggctttctc tgatgacttg gcgacaattg catttattaa ggaaacatat
     7081 cataaagttg aggtagaaaa acgatgaaaa ttcaagattt attgagaaaa gatattatga
     7141 ttctcgattt acaggctatt tctaaagaag ttgccattga cgagatgatt actaaattag
     7201 ttgaaaaaga tattgtacat gattttgatg tctttaaaaa gagtatcatg acacgtgaag
     7261 aacaaacatc aacagggctt ggtgatggga ttgccatgcc tcattctaaa aatattgtag
     7321 tagataaacc agcggtcttg tttgcgaaat caaataaagg tgtggattat aaggctttag
     7381 atggtcaacc aacggatctc ttctttatga ttgctgcgcc tcaaggagca aatgatactc
     7441 acttggctgc gctagcagaa ttatcacaat accttttgaa agacggcttt gctgataaac
     7501 ttcgtgctgc agcgacacca gaagcagtca ttgctgtttt tgatgaagcg tcaacagcta
     7561 aagaagaagt ggttgctcca acaagtggtc aagactttat cgttgctgtt acagcttgtc
     7621 cgacaggaat tgctcacact tatatggcag aagaggcttt gaaaaaacaa gctgcagaaa
     7681 tgggagtagc tattaaagtt gaaacaaacg gtgcttctgg tgtggctaat cgtttaaccg
     7741 ctgaagatat tcagagagct aaaggagtta ttgttgcagc tgataaagcg gttgaaatgg
     7801 accgttttga tggtaaacaa ttcattgctc gccctgttgc agatggtatc aagaaaagtc
     7861 aggaattgat ttctttgatt ttaaacaatg aaggaaacac ttatcatgct aaaaatggaa
     7921 aatctgaaac agcagtatca actgagaaaa caagtttagg cggtgctttc tataaacact
     7981 tgatgggcgg tgtctcacaa atgttgccat ttgttattgg tggcgggatt atgattgctc
     8041 tagcattttt attggataac atgcttggtg tgccaaatga tcagcttgga agtcttggat
     8101 cctatcatga aatagcagct atttttatga acattggtgg agcagccttt tccttcatgt
     8161 taccagtact agcaggttat atcgcttatt ctattgctga aaaaccgggc ttagtagctg
     8221 gttttgtggc aggtgccatt gcctcaaatg gtcttgcttt tggtaaggta ccatttgcag
     8281 caggaggaga agtgagcttg ggattaacgg gcgtgccatc aggtttcctt ggggcgcttg
     8341 tgggtggttt ccttgccggt ggtgttattc ttgcccttcg taaattgttg gcaggcctac
     8401 cacgttctct agaaggggtt aaatctatcc tcctttaccc attacttggc gtccttgtca
     8461 ctggtttctt gatgcttttt gtcaatattc caatggcagc tattaacaca gctcttaatg
     8521 atttcttaca aggtctttca ggaagctctg ctgtccttat gggacttctt gttggtggaa
     8581 tgatggctgt tgacatgggt ggtcctgtta ataaggcagc ttatgttttt ggtacaggaa
     8641 ctttagcagc tactgtggca aatggtggtt cggtcgttat ggccgctgtt atggcaggtg
     8701 gtatggtacc tcctcttgct gtttttgtag ccactctctt gtttaaagat aaatttacca
     8761 aagaagaacg cgaatcaggt ttgaccaaca ttgtcatggg actttctttc atcactgaag
     8821 gagcaatccc atttggcgca gctgacccag cgcgtgcaat tcctagcttt attgctggtt
     8881 ctgccttgac aggagctctt gttggtttgg ctggcattaa attaatggcg ccacatggtg
     8941 gtatcttcgt aatcgcttta acaagcaatc caatcttata tcttgtcttt gttgtgattg
     9001 gtgcccttgt atcaggtatc ttatttggcg ctcttcgcaa aaaagcctaa aaggtaaaga
     9061 acttttttct tactaaaact agaatctgtc aaggttctag ttttttgcta tactagagtt
     9121 aaaggataag aaatgaggac ctttgaaggt gaaaaaaagg agaagaaggg ctaaatcatc
     9181 agtaaatcga cttgtcttag ggttagtatt acttaatctg attgttagta tgtggacact
     9241 aaaattggga aaccagcgat tagctccgta tgcggatcac gaaactctga catttgtcag
     9301 gaagattagt catgctgctc aatcagtcgc tcaaaagaaa cagttataca gttcggtgat
     9361 gatggctcag gccattttag aatccaataa tggcaagtca caactaagtc aaaaacctta
     9421 ttataatttt ttcgggatta aggggagcta taaagaacgg tcagtcattt ttccaacttt
     9481 agaagacgat ggacaaggga atctttatca aattgatgct gcttttcgtt cctatgggag
     9541 cctgacagct tgttttttag attacgcaag agttttgaat gatccacttt atgacaaaac
     9601 ccacaaaaag ttttggtctc attatcaaga tgctactgca accttaacag gcacttacgc
     9661 cactgataca acttacaata ccaaattaaa tgaattgatt gaatggtatc aactcactaa
     9721 ttttgatggt ctaatgaaat agttatccac aattttaaaa aaaatcagaa gaaatatgtc
     9781 gatttcaaga caaaagttat caatctcatt aaattatctg tggaaaagtt aatttaaacg
     9841 ttcgtgtgct ataatagaaa catagaaaat gtataaaaaa ggatatgtga ataatgacaa
     9901 aaaagaaagg taagcttgta cttatcagtc tttttgttct agcagcttgt ttaggagctt
     9961 atagtgcaat gagacaatct cataaaactt caaacgtgtc agctgagact atcgccagtt
    10021 cttcaacccg acattttatt gatgaaattg gtccaactgc tagtactatt ggtcaagaac
    10081 gtgatcttta tgcgtctgtt atgatagcac aagcgatttt agaatcaagt aatggtaaat
    10141 caagtctaag tcaagcacct tattataatt ttttcggtat taagggtgcc tataacggtt
    10201 cttctgtgac gatgtcaact tgggaagatg atggtaatgg caatacctat acgattgatc
    10261 aagcctttag agcttatcca agtattgcag actcccttaa tgactatgca gacttgctaa
    10321 gttctagcac ttatataggt gctagaaaat caaacacgct atcgtatcaa gatgctacag
    10381 cagctctaac tggcttatac gctacagaca ccagttataa cttaaaacta aataatatta
    10441 ttgcaaccta tggtttgacg gcttatgatg ttgctaatag ctcagctcaa gaaactggtc
    10501 tagcaacttc gggttatgtt tggaatgagt atcgtcgtaa ttacactgat gcggagaccc
    10561 tagcagttga tgaggcttgg gctaaacgca tgacttatta atgtaacact aacaacaatc
    10621 tgcttgcact gaccccaaaa aagttggcta ctctattt
//
LOCUS       DATWEK010000048        10390 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.048, whole genome shotgun sequence.
ACCESSION   DATWEK010000048 DATWEK010000000
VERSION     DATWEK010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10390
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.048"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            555..872
                     /locus_tag="VCR92_001606"
     CDS             555..872
                     /locus_tag="VCR92_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEP4268657.1"
                     /translation="MIVRNGKNFLTRDAADQYYTIGGTSLVGEKTHETVLRETLEEVG
                     IRTKVNQLAFVVENHFDIDDVFWHNIEFHYLVSPLEDPKLEMIENASDRFVNGFQSIN
                     WIK"
     gene            996..2894
                     /gene="mnmG"
                     /locus_tag="VCR92_001607"
     CDS             996..2894
                     /gene="mnmG"
                     /locus_tag="VCR92_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEP4268658.1"
                     /translation="MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTE
                     IQPGDDKPNHFSFMSKDAEYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGL
                     EKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPVKATNDRVQELGFKPLTD
                     AMTAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMK
                     RMEEKRIPANIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEG
                     NGKAHRKY"
     gene            2984..4960
                     /locus_tag="VCR92_001608"
     CDS             2984..4960
                     /locus_tag="VCR92_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEP4268659.1"
                     /translation="MKKFRFETIHLIMMGLILFGLLALCVSIMQSKILILLAIFLVLL
                     FVVALLWYQKEAYHLSDLAHIELLNEQTEDNLKTLLDNMPVGVVQFDQETNAVEWYNP
                     YAELIFTTEEGFIQNSLIQQIITEKRREDISQTFEVSGNKYTSYIDVSSGIFYFFDSF
                     VGNRQLADASMLRPVVGIISVDNYDDITDDLSDADTSKINSFVANFIDEFMESKRIFY
                     RRVNMDRYYFFTDFKTLNDLMDNKFSVLEEFRKEAQDAQRPLTLSIGISFGEENHSQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPIYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFAGNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISVSQAMGLVTPRSLLVMVDHSKISLTLSKEFYEQFQNVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSKGSDSVEIQNISATDFEEYKQINEIILQGERLGDSIIVAAGEKNHLY
                     SNVIASKAADTILSMAHVEASFVLVETASHKIAISARSRSKINVQRVMEKLGGGGHFN
                     LAACQLTDISLPQAKHLLLKTINMTMKETGEVES"
     gene            4957..5409
                     /gene="rplI"
                     /locus_tag="VCR92_001609"
     CDS             4957..5409
                     /gene="rplI"
                     /locus_tag="VCR92_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEP4268660.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSI
                     GELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISE
                     ELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLTITEA"
     gene            5439..6806
                     /gene="dnaB"
                     /locus_tag="VCR92_001610"
     CDS             5439..6806
                     /gene="dnaB"
                     /locus_tag="VCR92_001610"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEP4268661.1"
                     /translation="MRLPEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDD
                     FYKYAHKIIFRAMITLSDRNDAIDATTIRTILDDQDDLQSIGGLSYIVELVNSVPTSA
                     NAEYYAKIVAEKAMLRDIIARLTESVNLAYDEILKPEEVIAGVERALIELNEHSNRSG
                     FRKISDVLKVNYEALEARSKQTSNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGK
                     TAFVLNIAQNVGTKQKKTVAIFSLEMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWN
                     NVTIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIVIDYLQLITGTKP
                     ENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDA
                     DIVAFLYRDDYYRKEGDDAEEAVEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSSIA
                     QFEER"
     gene            6823..7095
                     /locus_tag="VCR92_001611"
     CDS             6823..7095
                     /locus_tag="VCR92_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEP4268662.1"
                     /translation="MSDAFTDVAKMKKIKEDIRAHEGQLVELTLENGRKREKNKIGRL
                     IEVYSSLFIIEYSDSSDTPGAIDNSYVESYTYSDILTEKTLIRYLD"
     gene            7825..8436
                     /gene="rpsD"
                     /locus_tag="VCR92_001612"
     CDS             7825..8436
                     /gene="rpsD"
                     /locus_tag="VCR92_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEP4268663.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKEGTLGFNFMVLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(8593..9756)
                     /locus_tag="VCR92_001613"
     CDS             complement(8593..9756)
                     /locus_tag="VCR92_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEP4268664.1"
                     /translation="MNIKEYKKKNGTIIYRTSVYLGVDQVTGKKARTTITASTKKGVK
                     IKARDALNNFAMNGYTVKEKPTVTTYKELTALWWESYKNTIKPNSRQSMEGIVRLHIL
                     PAFGDCKLSKLTTPVIQQQVNKWANNANKGIKGAYANYSFLNNINRRILQYGVTMQVI
                     EHNPARDVIIPRKQNNKEHKVKFFSNQELKQFLNYLDDLDLSSYENFFDYVLYKTLLA
                     TGCRIGEVLALEWSDIDLKKGTIKVSKTLNRYQETNTPKSKAGLRDIEIDRATVLLLK
                     QYKNRQQVLSWDLGRSETIVFTPFTTKYAYACLLRKRLQKHFKAAGVPDISFHGFRHT
                     HATIMLYAGIEAKDLQYRLGHSNISMTLNTYVHATKEGAKKAVSIFETAISNL"
     gene            complement(9936..10379)
                     /locus_tag="VCR92_001614"
     CDS             complement(9936..10379)
                     /locus_tag="VCR92_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4268665.1"
                     /translation="MENRLQKIRKEQTNLNQKDFFDQVVNKKLNLDISFRTYQNWENP
                     KNTIKPDKAQILADYFGVWLPYLLGNSNIRTEEQANFLAEMNKRINSEGDSFSFDMTA
                     TESDEHDLLYNYRQLETPYKNQVRKFTRDMWELQKESKNFSPKSP"
BASE COUNT         3304 a         1659 c         2119 g         3308 t
ORIGIN      
        1 attacaacag atattttgat gattaggtat ttcgtaaaac agattatttc atgattatta
       61 gtacctatta tctaatacta aatgtgtaaa aaattattgg aaatttctag ttatactttt
      121 atggttttgt tatcggcgtt cttacttgta gacttagaaa caacggtatc tgtattttac
      181 tactttagaa gatatcaaaa aatcgtatga taatactgat gacattttta tttctcgcct
      241 cgctagatta gacatagtga tacttttgta atcattttaa aaacattaca atagattgac
      301 agagatgtaa aaacattgac attactgtaa aggtctgtga tgaaatcaat attgacaatc
      361 actaatcatt tttttaaaat agataataac aatcggaatg atggtcaaag ctcatgaaag
      421 ttgtaggttt ttttgtcctg caatcttcta gggttttggc cctttttatg gtttagctct
      481 agaattgaga tggctaatag gactgggatt tagaatcact agaggtcaga taactttagt
      541 ttacgagcta gtgcttgatt gttagaaatg gtaagaattt tttaactaga gatgcagctg
      601 accaatatta caccattggt ggtacaagtt tggtaggtga aaaaacgcat gaaactgttt
      661 tacgtgaaac cttagaggaa gttggtattc gaactaaggt taatcaactg gcttttgtgg
      721 ttgagaatca ttttgatatc gatgatgttt tctggcataa tattgaattt cattatttgg
      781 taagcccctt agaagaccct aaactagaaa tgatagagaa tgcaagcgac aggtttgtga
      841 atggattcca atcaatcaac tggatcaaat gaatcttgtt cctgagtttt tacaaaccga
      901 gttggctaaa tggccaggac atattgtccg cattgaaggc taaactaaag cgtatgattt
      961 taaatgaata gactgaaata aaggatttta aaaaaatgac acatgaattt acagaaagct
     1021 atgacgtcat tgtcataggt gcaggtcatg ctggtgttga agccagtttg gccactagtc
     1081 gtatgggttg taaaacttta ttggcaacaa tcaaccttga tatgttggct tttatgccgt
     1141 gtaatccttc tattggagga tctgccaaag ggatagtggt tagagagatt gatgctcttg
     1201 gcggcgaaat gggtaaaaat attgataaaa cctatatcca gatgaaaatg cttaatacag
     1261 gtaagggacc agctgtacgc gctctccgag ctcaagcaga taaatccctg tatgcgcgtg
     1321 aaatgaaaca tacggttgaa aaacaggcta atttgactct tcgccaaacg atgattgatg
     1381 atattctagt tgaagatgga cgagttgtag gtgttttaac agccacagga caaaaatttg
     1441 cagctaaggc agttgtagtg acaacaggaa cagctctgcg tggcgaaatt attttaggag
     1501 aactcaaata ttcttctggg cctaataata gtttggcatc agtaacttta gcagataatt
     1561 taaaaaaact cggcttagaa attggcagat tcaaaacagg aacgcctcct cgtgtcaaag
     1621 catcttctat taattacgat caaacggaaa ttcagccagg tgatgacaaa cctaatcatt
     1681 tttcatttat gtcaaaagat gctgagtatc tcaaagatca aattccctgc tggttgactt
     1741 atacgaatca aactagtcat gatatcatta atcagaacct ttacagagca ccgatgtttt
     1801 ctggcattgt taaaggtgta ggccctcgtt actgcccatc tattgaagat aagattgttc
     1861 gctttgctga taaagaacgt catcaacttt tcttagagcc agaggggcgt gatacagaag
     1921 aagtgtatgt tcaagggttg tcaacgagtc ttccagaaga tgtccaaaaa gatttgattc
     1981 attcgatcaa aggacttgaa aaggctgaaa tgatgcgcac tggttatgct attgaatatg
     2041 atattgtttt acctcaccag ctacgtgcca cacttgaaac caagctaatt tcaggactct
     2101 ttacggctgg gcaaactaat ggaacttctg ggtatgaaga ggctgctggc caaggactta
     2161 ttgctggaat caatgctgct ttgaaagttc aaggtaagcc agaacttatt ttgaaacgga
     2221 gcgatgctta tattggcgtt atgattgacg atttggttac caaaggaacc ttggaacctt
     2281 atcgattgtt gacatcgcga gctgagtatc gtttgatttt acgtcatgac aacgctgata
     2341 tgcgtttgac agagattggt cgcgacattg ggttggttga tgatgagcgt tggaaggcct
     2401 tcgaaattaa gaaaaaccaa tttgataacg aattaaaacg tctgaacagt atcaaattaa
     2461 aaccagtaaa agcaaccaac gatcgtgtgc aggaacttgg ttttaaacca ttgacggatg
     2521 ctatgacagc taaagaattt atgcgtcgcc cagaaattga ttatgcgact gcagtctctt
     2581 ttgttggtcc tgcggctgaa gatttagatg ctaaaatcat tgaactttta gaaacagaaa
     2641 tcaagtacga aggctatatt cgcaaagctt tagatcaggt tgctaagatg aaacgcatgg
     2701 aagaaaaacg tattcctgca aatattgatt gggatgctat tgattctatt gcaactgagg
     2761 cgcgtcagaa atttaagaaa attaatcctg aaacaattgg acaagctagt cgtatttcag
     2821 gagtcaatcc tgcggacatc agtatcttga tgatttattt agaaggaaac ggaaaagctc
     2881 atcgaaaata ttaaatggaa atgaaattgt aatctcaaag caagtggaag ctctgtattt
     2941 cagggctttt ttatggtata atgtgtgctt aagaggttat aagatgaaaa aatttcgttt
     3001 tgaaaccatt catttgatta tgatgggatt gattttattt ggactactgg cactttgtgt
     3061 cagtattatg caatcaaaaa tattaatatt attagctatt tttctcgttt tgctatttgt
     3121 tgttgctctt ttatggtatc aaaaagaagc ttatcactta tcagacttag ctcatattga
     3181 gctcttaaat gaacaaacag aagataacct aaaaacgcta cttgataata tgcctgttgg
     3241 agtagttcaa tttgatcaag agaccaacgc tgtagaatgg tataatcctt atgcagaatt
     3301 aatttttaca actgaagagg gttttataca aaacagtttg attcagcaaa ttattacgga
     3361 aaaacgtcgt gaagatattt ctcaaacatt tgaagtttct ggtaataaat acacttctta
     3421 tattgatgta tcatcaggaa ttttttattt ttttgatagc tttgtgggaa acaggcaatt
     3481 agctgatgct agtatgttaa gaccggttgt tggcattatt tcggttgata attatgatga
     3541 tatcactgat gatttatcag atgcagatac ctcaaaaatt aattcatttg tagctaactt
     3601 cattgatgag tttatggagt caaaacggat tttttaccgt cgtgttaata tggatcgcta
     3661 ctatttcttt acagacttta aaacattaaa tgatttgatg gataataaat tttctgtctt
     3721 agaagagttt cgtaaagaag ctcaagatgc tcaacgccct ttaacactca gcataggaat
     3781 ttcttttggt gaagaaaatc atagccagat tggacaggta gctcttgaga atcttaatat
     3841 tgcgcttgtt cgtggtggtg atcagattgt cattcgtgaa aatgcggatc atacgaatcc
     3901 aatttatttc gggggagggt ctgtttctac agttaaacgt tcaagaacac gtacccgtgc
     3961 tatgatgaca gctatttcag atcgaatcaa gatggtggac aatgttttta ttgttggaca
     4021 taggaaactt gatatggatg cactaggttc agctgttggt atgcaatttt tcgcaggtaa
     4081 cattattgaa aatagttttg ccgtttacaa tccagatgag atgagtccag atattgaaag
     4141 ggctattgag cgattgcagg ctgacggaaa gactcgtcta atcagtgttt ctcaagcaat
     4201 gggtttagtg actccaagat cacttttagt aatggttgac cattctaaga tatctttaac
     4261 actttctaaa gaattttatg aacagtttca aaatgttatt gtagttgatc atcacagaag
     4321 agatgatgat tttcctgata atgctatctt aacttttatt gaaagtggag caagtagtgc
     4381 tgcggagctc gtcactgagt taattcaatt tcaaaatgct aaaaaacgtt taaataagat
     4441 ccaagccagt gttttaatgg caggtattat gcttgatact aaaaattttt ctacgcgagt
     4501 gacaagtcgt acctttgatg tcgctagtta cctaagaagc aaaggaagtg atagtgttga
     4561 aattcaaaat atatccgcaa cagattttga agaatataag caaataaatg aaattatttt
     4621 acaaggagaa cgtcttggtg acagtatcat tgtagctgca ggagaaaaaa atcatcttta
     4681 tagcaatgtt attgctagta aagctgcaga tacgatactg tcaatggctc acgttgaggc
     4741 tagctttgta ttagttgaaa cagcttctca taagattgct atttcagcta gaagtcgtag
     4801 taaaatcaat gttcaacgtg tgatggaaaa attaggtgga ggaggccact ttaatcttgc
     4861 tgcctgtcag ttaacggata tcagtcttcc ccaagcgaag cacttattat tgaaaactat
     4921 taatatgaca atgaaagaaa caggagaagt agaatcatga aagttatttt tttagcagat
     4981 gtaaaaggaa aaggtaaaaa aggagaaatc aaagaggtcc caacaggcta tgctcaaaat
     5041 ttccttatta agaaaaattt agctaaagaa gcaactagtc aaagcatcgg tgaattaaaa
     5101 ggaaaacaaa aagctgaaga aaaagctcaa gctgaaatat tagcagaagc tcaagctgtc
     5161 aaggctgttt tggatgagga caaaacacgt gttcaatttc aagaaaaagt tggtccagat
     5221 ggacgtacat ttggttccat cacagctaaa aagatttcag aagaattgca aaagcaattt
     5281 ggtgtaaaag ttgataaacg tcatattgtt ttagatcatc ctatccgcgc cattggtcta
     5341 attgaagttc ctgtgaaatt acataaggaa gtaacagctg agattaaatt gactatcaca
     5401 gaagcataat ataaaaaaca tcacaagatt tggaggttat gaggttgcct gaagtagctg
     5461 aattacgagt tcaaccccaa gatttactag cagagcaatc tgttcttggg tcaatcttta
     5521 tctcacctga taagctgatt gcagtgagag aatttatcag tccagacgat ttttataagt
     5581 acgctcataa aattatcttt cgggcaatga ttaccctcag cgatcgtaat gatgccattg
     5641 atgcaaccac tataagaaca atcctagatg atcaagatga tctgcaaagt attggtggct
     5701 tatcctatat tgttgaacta gttaatagtg tcccaactag tgctaatgca gaatattatg
     5761 ctaaaattgt agctgagaaa gctatgttgc gtgatattat tgctaggttg acagaatctg
     5821 tcaacctagc ttatgatgaa attttaaaac cagaagaggt tatcgctgga gttgagagag
     5881 ctttaattga actcaatgaa catagtaatc gtagtgggtt tcgcaaaatt tcagatgtgc
     5941 taaaagttaa ttacgaggct ttagaagcac gttctaagca gacttcaaat gttacaggtt
     6001 taccaactgg ttttagagac cttgacaaga ttacaacagg tttacaccca gatcaattag
     6061 ttattttagc tgctcggcca gcagtgggga agactgcctt tgttcttaat attgcgcaaa
     6121 atgtggggac taagcaaaaa aagactgttg ctattttttc tttggaaatg ggtgctgaaa
     6181 gtttagtaga tcgtatgctt gcagcagaag gaatggttga ttcgcacagt ttaagaacag
     6241 ggcaactcac agatcaggat tggaataatg taacaattgc tcagggagct ttggcagaag
     6301 caccgattta tattgacgat acgcccggga ttaaaattac tgaaatccgc gcaagatcac
     6361 ggaaattgtc tcaagaagtg gatggtggtt taggtcttat cgtaattgac tacttacagt
     6421 tgattacagg aactaaaccc gaaaatcgtc agcaagaggt ttcagatatt tcaagacagc
     6481 ttaaaatcct agctaaagaa ttgaaagtac cagttattgc cctaagtcag ctttctcgtg
     6541 gcgttgagca aaggcaagat aaacgaccag ttttatcaga tattcgtgaa tcaggatcta
     6601 ttgagcagga tgccgatatt gtagccttct tataccggga cgattattac cgtaaagaag
     6661 gtgatgatgc tgaagaagct gttgaagata acacaattga agttatcctc gagaaaaata
     6721 gagctggggc gcgtggaaca gtcaaactga tgtttcaaaa agaatacaac aaattctcaa
     6781 gtatagccca gtttgaagaa agataagaaa gagagacaaa aaatgagcga tgcatttaca
     6841 gatgttgcaa aaatgaaaaa aattaaagag gacataagag cccatgaagg acagttagta
     6901 gaattaaccc ttgagaatgg acggaaacgg gaaaaaaata aaattggtag gcttattgag
     6961 gtttacagtt cgctctttat cattgagtat agtgatagct ctgatactcc aggagcaatt
     7021 gataattctt atgtcgaatc atacacctat tcagatattt tgacagaaaa aacattaatt
     7081 cgttatttag attgattttt gcctcataga ggctttttct ttacaataaa ttgatataat
     7141 tattagcgat agaagattat tctgcctgta ttctttttat tttgaaaaaa ttcctataaa
     7201 agataatatt tttaggttag attgaaggaa aaaagaggtc ttcaccatgg ttaagcaaat
     7261 gatcttagta ctaaggttaa aagattatcg tgaaataaag ttttgacaca agtgtaatta
     7321 atagaggaac ttgaagtatc cggtaaaact atcttgaagt gaaaaaacga gtagacctcc
     7381 cctgataaat acaatatact agccatttca gagcaattaa gagtttccag tgaagtgctt
     7441 ttgatagaga gctaagaaaa aaacagtcaa ggtttaagaa ctgcaaatta gcatttaaat
     7501 tattttttgt taatgacagt tgtctttatt accataacta taacttctta taatatagcc
     7561 ttcttaattc atcagtggtg gttcgtccca tatctgacct taaaatatta aactgatcat
     7621 cagatgatag atagactgac tttacaaaac aactttctta tggtaaactg ttctttgtgc
     7681 gaaataacag cagaaaaata tgaagctcgt caacaggtgg ttatctattc aagtaacctt
     7741 tgctgtttag gcgaaaaccc cctgcacgaa tcaggatttt ttaaaccgtt atttcctcaa
     7801 aaaatttaga ggaggacatg taatatgtca cgttatactg gtccatcatg gaaacaatca
     7861 cgtcgccttg gtttatcact tacaggcaca ggtaaagaat tggcacgtcg taactacgtt
     7921 cctggtcaac acggtccaaa caaccgtagc aaactctcag aatatggttt gcagttagct
     7981 gagaaacaaa aacttcgttt ctcatacggt ttaggtgaaa aacaattccg taacttgttc
     8041 gttcaagcta caaaaatcaa agaaggaact cttggtttca actttatggt tcttttagaa
     8101 cgtcgtcttg acaacgttgt ttaccgtcta ggtttagcaa ctactcgtcg tcaagcacgt
     8161 caattcgtta accacggtca catccttgtt gacggtaaac gcgttgatat cccttcatac
     8221 cgtgttgatc caggtcaagt gatttcagtt cgcgaaaaat caatgaaagt acctgcaatc
     8281 cttgaagctg ttgaagctac tcttggacgt ccagctttcg tatcatttga tgctgaaaaa
     8341 cttgaaggtt cattgactcg ccttccagaa cgcgatgaaa ttaacccaga aatcaatgaa
     8401 gcacttgtcg ttgaattcta taacaaaatg ttgtaatatt ttattgaata ggataggctt
     8461 aaaagccttg atactaagca ctttggggca ttattccaag gtgctttttt tgattttact
     8521 acccttttag ttctctttag tcggatttta gtatagtaag agggtagccc caaagtgggg
     8581 cacccttgtt aattataaat tgctaatagc tgtctcaaaa atcgagacgg cttttttagc
     8641 gccttctttt gttgcatgga cataagtatt caatgtcatt gagatattag agtgtcctag
     8701 tctatattgc aagtctttag cctctatccc agcgtaaagc ataattgtag cgtgggtgtg
     8761 gcggaagccg tggaaactaa tatcaggcac gccagcagct ttaaaatgct tttgaagcct
     8821 ttttctaagc aaacaagcgt aggcgtattt tgtggtaaac ggagtaaaaa caatcgtctc
     8881 agaccgtcct agatcccaag ataaaacttg ctgacggttt ttatattgct taagaagtaa
     8941 gacggtagct ctatcaatct caatgtctct taatcctgct tttgatttag gagtgtttgt
     9001 ctcctgatat ctattcaaag ttttggaaac cttgatagtt ccttttttta gatcaatatc
     9061 agaccattca agagctagaa cttctccaat ccgacaacca gtagcaagca aggtcttata
     9121 aagaacgtaa tcaaagaagt tttcatagct agataaatct aagtcatcta aatagttcaa
     9181 gaattgcttt agttcttgat tgctgaagaa ctttacctta tgttctttgt tattttgttt
     9241 tcgaggaatg atgacgtcac gagctggatt atgttcaata acttgcatag taacgccata
     9301 ttgtagaata cggcgattga tattatttag aaaactgtag ttagcatatg cgcctttaat
     9361 gcccttatta gcgttgttag cccacttgtt aacttgttgc tgaataacag gggtagttag
     9421 cttagatagc ttgcaatccc caaatgcggg caaaatatga agtcttacaa tcccttccat
     9481 agattgccga gagtttggtt tgatcgtatt cttgtaactc tcccaccaaa gggctgttag
     9541 ctctttataa gtggttactg tcggcttctc tttgacggta tagccattca tagcaaagtt
     9601 atttagagca tcacgagctt ttattttaac ccctttttta gttgaagctg taatagttgt
     9661 gcgagccttc ttacctgtta cctggtcgac accaagatag acactagtgc ggtaaatgat
     9721 tgtaccgttc ttctttttgt attcttttat gttcatgata atacctttct aacatcagta
     9781 agcaagtatg ggatttagtt aggtatttag gttttatcat gggtgatagt tggttatctg
     9841 gtagggtggc gataaggtag agggtgtgtt aatgctatgg ttgtcaatat aagtgttgat
     9901 tattgtttgg tgggatagtt gcgagctggt cggtatcagg gagattttgg agagaagttt
     9961 ttgctttctt tttgcaactc ccacatgtct ctagtaaatt ttctaacttg atttttatag
    10021 ggagtttcaa gctgtctgta attatataat aggtcgtgtt catcagattc ggttgcggtc
    10081 atgtcgaagg aaaatgaatc accttcagag ttaattcgct tgttcatttc tgctaaaaaa
    10141 ttcgcttgct cttctgttcg gatattgcta tttcctagaa gataagggag ccatactcca
    10201 aaatagtccg ccagtatttg agctttatca ggcttgattg tattctttgg gttttcccaa
    10261 ttttgatatg ttctaaatga aatgtctaga tttaatttct tatttacgac ttgatcaaaa
    10321 aaatcttttt gattgagatt tgtttgttct tttcttattt tttgtagcct attttccaaa
    10381 agtattctcc
//
LOCUS       DATWEK010000049         9846 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.049, whole genome shotgun sequence.
ACCESSION   DATWEK010000049 DATWEK010000000
VERSION     DATWEK010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9846
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.049"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            316..465
                     /locus_tag="VCR92_001615"
     CDS             316..465
                     /locus_tag="VCR92_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268666.1"
                     /translation="MRERNEKFIGVLKDMHMQILRDFTNEEDPLTRCELAKGFLEIGD
                     YLSKQ"
     gene            complement(451..666)
                     /locus_tag="VCR92_001616"
     CDS             complement(451..666)
                     /locus_tag="VCR92_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268667.1"
                     /translation="MKISNSKDLALAIVASSSPTLSIEDKIKLYEDSVEAIKKHNLPF
                     VEAEKQEQINNGKVIAEALERGESLFG"
     gene            725..883
                     /locus_tag="VCR92_001617"
     CDS             725..883
                     /locus_tag="VCR92_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268668.1"
                     /translation="MNWKKLMFGDLEYTFASRDGKEKTSIEFEGGLLPALLVLGGITW
                     LAAWFITK"
     gene            complement(913..1512)
                     /locus_tag="VCR92_001618"
     CDS             complement(913..1512)
                     /locus_tag="VCR92_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268669.1"
                     /translation="MDLLKNTNFLIPLISAIVSVSSIFISNWLGYRSQIRKLKFDEEK
                     EIYLTLYVPLIKWMNSQSFNNKSYYWLVAFPRYTTNAQDFLTGLLLKNFEKLPVSVAM
                     RYSEYTLNSATSLHFYRNTEYDYDYETFAKKASELFDLIIEQLLTEGTILSQKLSLPN
                     LSKSTLENFLADKKNYIGPRFLSLETHNKPLRPERPLPF"
     gene            1566..1775
                     /locus_tag="VCR92_001619"
     CDS             1566..1775
                     /locus_tag="VCR92_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268670.1"
                     /translation="MRPKKYPYSQKNYPAPKLHNVIETDNQFLIDDKRIHYVIEDSVK
                     TKTLGDGYVEVTLSIIAKSFTKSQG"
     gene            complement(1764..2150)
                     /locus_tag="VCR92_001620"
     CDS             complement(1764..2150)
                     /locus_tag="VCR92_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268671.1"
                     /translation="MFDYFKLYIIVLETFVETKPDDAYSLFDNLSLNSEFVKFSKDLD
                     KNIVISGTLEVIDNLLDDCLIKGKRRPTKDITFYFFDGVTTTGYLYLQSLKDNNFSSR
                     LKNVLKEEGIPLTPTSITRTIAKLTL"
     gene            2224..2451
                     /locus_tag="VCR92_001621"
     CDS             2224..2451
                     /locus_tag="VCR92_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEP4268672.1"
                     /translation="MTKKQRLKQEHLKPKKRLREERLKREYTKMYMADLIGLKNRKGY
                     SEKEDGLQPFKDYEMAIISQKFNVSESELFF"
     gene            complement(2559..3068)
                     /locus_tag="VCR92_001622"
     CDS             complement(2559..3068)
                     /locus_tag="VCR92_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268673.1"
                     /translation="MELFNTIIGVIALIVAVIALVHSIYYNMVKIKLSDCYISRVDKG
                     YDWMYDFSISNLSNVSVIIKKIELYNKDGKLISDNGFNPFQKYEADMQNEADDYYGLS
                     MPNYYMPLDYQWESSPFKSDTEVYPSSRENFSYYLDEKPVKIKITTDKRIHQFRKYQL
                     FFPHFDNNS"
     gene            complement(3327..3536)
                     /locus_tag="VCR92_001623"
     CDS             complement(3327..3536)
                     /locus_tag="VCR92_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268674.1"
                     /translation="MNLEELTPLLNSIDDFETVILHSLVGDFVIDHWIEPNRKNETLI
                     FMHNDQTTELKLSAILGTSTIPKSL"
     gene            complement(3686..3925)
                     /locus_tag="VCR92_001624"
     CDS             complement(3686..3925)
                     /locus_tag="VCR92_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268675.1"
                     /translation="MDTKEFMKVVSKHINQNFNVDNQLVEFVVAELNQMNAPITQKQA
                     QHIVNILEYVSKSTSKSTIAAMTNALLELGVLKGD"
     gene            4092..4319
                     /locus_tag="VCR92_001625"
     CDS             4092..4319
                     /locus_tag="VCR92_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4268676.1"
                     /translation="MWGKIEALLIEKKMTKYELSQKAGLNQNCLIDLKKGRKKSLKFD
                     DVVKIADVLGVSLDEFRYQKKSDGNRTLKKF"
     gene            4356..4652
                     /locus_tag="VCR92_001626"
     CDS             4356..4652
                     /locus_tag="VCR92_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268677.1"
                     /translation="MAIEIFGPEFRKKLLEDLIALNMEAIKIAQTKNAKSIEWITMKR
                     LEKETGWGRTKLTQWREQGKFNFKRSSENGKVLYDLADVNRFLRTSGYEKGETT"
     gene            4649..4786
                     /locus_tag="VCR92_001627"
     CDS             4649..4786
                     /locus_tag="VCR92_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268678.1"
                     /translation="MKLLDFIFAKPKKQEPIKHDTLRASSEKQWAEFDAYMRKQYGRQ
                     A"
     gene            4867..5196
                     /locus_tag="VCR92_001628"
     CDS             4867..5196
                     /locus_tag="VCR92_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268679.1"
                     /translation="MKTKIEIMRDFFKENPESTQRQASEKLGFTENTVKQYIWRDAKR
                     GYCIKDEEGRVTYLNIEDELSLINEWKSEIRRELIEQLLSANRHETSSEQIRMNAKTI
                     NQILGEI"
     gene            5196..5390
                     /locus_tag="VCR92_001629"
     CDS             5196..5390
                     /locus_tag="VCR92_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268680.1"
                     /translation="MEGMKKYINGQIKLIDTIEECVKEKWPEFDDKKVHKISLAIYQG
                     WSLTDINSTLEAIEMDLDRK"
     gene            5387..5671
                     /locus_tag="VCR92_001630"
     CDS             5387..5671
                     /locus_tag="VCR92_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268681.1"
                     /translation="MRIYVNKKGKPSVEFEFEDRRGGMFDTRLMLKESPLKEEFKADM
                     YKAIDDVLKKYEDIFDTPIFKELIIGKEEDIRKMIDYDDKFTELFGGIRH"
     gene            5668..6351
                     /locus_tag="VCR92_001631"
     CDS             5668..6351
                     /locus_tag="VCR92_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEP4268682.1"
                     /translation="MKITKATEITKTHNWRILIYGKPGNGKTYLTNYLKGKTLILDMD
                     HSSKTIAGNENIDIIQFDRTHPSDFMTEFLTELPELIKEYDNLVIDNITSWQSDWFIE
                     QGRKSKNGITNELQQYNMWTNYYLRVLTTIYSQPTNIFVTAWESTQDLTLESGQIITQ
                     YVPDIRKQVLSQTLGLTDVVGRIQVNPKTGGHGILLQGSDGLYAKNRLDNRTVCKAEE
                     LFNFEGSDA"
     gene            6387..7790
                     /locus_tag="VCR92_001632"
     CDS             6387..7790
                     /locus_tag="VCR92_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017770133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEP4268683.1"
                     /translation="MNEARRHILKHNVMIVSPPGSGKSVVISDIAKSATQKNGHVLFL
                     VHRKELIDQITNSFKFHGIDMNKVDLMTVGKAKNRLDKLTKPTLIITDEGHHGKASTY
                     QIIYEYFSDVPRIGFTATPWRLSGDGFTDTYDVMVLGKTVEWLINNNKLAPYDYYSVL
                     SIDTAKLKVQNGDYSNKSIDESFGKKIFGDVVQEYIKKANGQKAILYAHSVEASQAFA
                     KEFQSMGINAIHADAKTPKAKRDKIMKDFRDGKIQVICNVDLISEGFDVPDCTVTILC
                     RPTKSLVLFLQQSMRSMRYQPNKKAIILDHVGNWNIHGLPDTPHHWENYFRGGWKKKS
                     NKTNTVHAKECSVCSALWPLSQQLCELCNHDFGLKEKQEKERIEAELELIKRERFRIK
                     QLANKKFGKDLKTNWEIAQARVKDAGKGKPLYKLIYFYLKTDWVETNVNELAEVTGKS
                     EKEIYSAYNWLKKKLRG"
     gene            7795..8277
                     /locus_tag="VCR92_001633"
     CDS             7795..8277
                     /locus_tag="VCR92_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000896928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF669 domain-containing protein"
                     /protein_id="HEP4268684.1"
                     /translation="MAGFTTDFSEVKEHAEFKEQPYEMIVYDAYEAVNERNGKKRVVI
                     DYVVRNDIKQEMQNYHLWDEQYPNSQTGKYHIGILMGKAKALGIKEGQHYDSFEAFLN
                     DFKGRTAKVTVKLDEYNGNKYPKVRYANQSDVPNSYHVWKEKATGFTQAEIEEDDLPF
                     "
     gene            8295..>9846
                     /locus_tag="VCR92_001634"
     CDS             8295..>9846
                     /locus_tag="VCR92_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage resistance protein"
                     /protein_id="HEP4268685.1"
                     /translation="MTSNEFIEALSKLTTETDWGDPIFGESVLKAELRKHLFKIVPID
                     HNGYIHKLFYSEMVKDEDVMYFVSDGRKTYRFLFGDTILKTDKQGNEYLTYSVENNFP
                     PFAKLVIDYILGAYTFFENKLYDIRYKQFKLIDDFTLQTKYGFKDSGHILEILQGIHK
                     TLNIQPINYIEPYQIACKDFIIDLENSEIINQPPLQNVSYFKYYEVDYKTAINSKSIA
                     EEYLEYVIADSNSLNNAILQSYFIAQVACGVRPKTNFFISKSGVRTGKGLRHIALSGL
                     FNKIDVELDTLKSNGFEALQAWAMFSGGEMALATEQGDIQGNAMERVLKIIATEKTHV
                     ARAIGQNQSMVNLTSVLCIDTNRTVALSDEMNGRKVLIQFKDRPKTETDYERESIFRK
                     YWLAFTDCDKNPKIDGCIGFLLNSLERFQKIGKWYQWKDVEVFNDIDLDEFQVALINA
                     LQEVDFVQRTDNKEVIDLSLQVYGKSNHALSKAISEIGVRSRSKKVNGKTVRGYEIEN
                     KTRFDKYIL"
BASE COUNT         3625 a         1520 c         1884 g         2817 t
ORIGIN      
        1 aaaaaagtaa ataaaaaaat ctcaaaaaga gataaaaaat agttgacaaa atatctcgtt
       61 ttgagatata ctataatcaa gcttaaggga ttaagcaaaa atgaaagtag gtacagctga
      121 tgaagtctag gctaaacaaa aagcctaaac acaaagaact agaagtcgaa atcaagattc
      181 tttggtttaa gcttaagatt cactactcaa tagagtggtg aggataatta gagggctaag
      241 aagccctctc cccctaacgg ggtaagttta gtttagcaca ttggctgtat ctccgcaaga
      301 atgaaaggag aggttatgag agaacgaaat gaaaagttca tcggagtgct aaaagatatg
      361 catatgcaaa ttttgcgaga cttcacaaac gaagaagacc ccttaacaag gtgcgagctt
      421 gctaaagggt tcctcgaaat tggtgactat ttatccaaac aatgactcgc cacgctcaag
      481 agcttcggct ataactttac cattattgat ttgttcctgc ttttcggctt caacgaaagg
      541 taaattatgt ttcttaatag cttccacaga gtcttcgtaa agtttgattt tatcttcgat
      601 agacaaagta gggctagaag aagcgacaat agcgagagct aaatcttttg aattagaaat
      661 tttcattagc ttatcctcct ttccgctagg ataagttgat tataacattt ttaggaggca
      721 caaaatgaat tggaaaaaac taatgtttgg cgatttagaa tacacgtttg ccagtcgtga
      781 cggcaaagaa aaaacaagca tcgaatttga aggtggctta ttgccagcgc tgttggtgtt
      841 aggtggtatc acttggttag cagcttggtt tattacaaaa taaaaagccc acaaggggcg
      901 gaaagggggg agttaaaatg gcagtggtct ttcaggtctt aggggtttgt tatgggtttc
      961 tagtgataaa aatctgggac cgatatagtt tttcttgtcc gccaaaaagt tctctaaagt
     1021 ggatttggat aagtttggta agcttagctt ttgggataat attgtccctt ctgttagcaa
     1081 ttgttcaata atgagatcaa ataattcaga tgcttttttg gcaaatgttt cataatcata
     1141 atcgtattcg gtgttacgat aaaaatgtaa agaggttgca gaatttaggg tgtattcaga
     1201 gtatctcata gcaactgata ctggtaattt ttcaaaattt tttaacaaca agcctgtcag
     1261 aaaatcttgt gcatttgttg tatatctagg gaacgccact agccaataat aacttttgtt
     1321 attgaatgat tgcgaattca tccattttat taacggtaca tagagggtta ggtatatttc
     1381 tttttcttca tcaaatttta atttcctgat ttgacttcta taaccaagcc aattgcttat
     1441 aaaaatagaa gaaacagaga ctattgctga aattaacgga attaaaaaat tggtattttt
     1501 caataaatcc atgattttct ccaatcattt tatttaaatt ataccacaga aagggggtgg
     1561 aatagatgcg ccccaaaaaa tatccgtata gccaaaaaaa ttatccagcg ccgaagcttc
     1621 ataacgtcat tgaaaccgat aatcagttct taatagatga taaaaggatt cattatgtta
     1681 ttgaagattc tgtaaagaca aaaacccttg gcgatggcta tgttgaagta acactttcca
     1741 taattgccaa gagttttaca aaatcacaag gttagtttgg cgatagtcct tgtgatagaa
     1801 gttggtgtaa gagggatacc ttcttcttta aggacattct ttaaacggct cgaaaaatta
     1861 ttatctttaa gactttgaag atataagtaa ccagttgttg ttacgccatc gaaaaaatag
     1921 aaagtaatat cttttgttgg gcgacgtttt ccttttatca agcaatcatc aagtaaatta
     1981 tcaattactt ctaaagtgcc tgatattaca atgtttttat ctaagtcttt agagaatttt
     2041 acaaattcac tgttaagact tagattatca aataagctat aagcgtcgtc tggtttggtt
     2101 tccacgaagg tttccaagac aattatataa agtttgaaat agtcaaacat cacattcacc
     2161 tcctttctgc ccatattata gcagattgga ggaactaaaa acagatagaa aggaggtggg
     2221 ggaatgacga aaaaacaacg tttaaaacag gaacatctca aacctaaaaa gcgtttaaga
     2281 gaagaacgtt taaaacgtga gtacacaaaa atgtatatgg ctgatttaat tggtttaaaa
     2341 aatagaaaag gttactctga gaaagaagat ggtttacagc cttttaaaga ttatgaaatg
     2401 gctatcattt ctcaaaaatt taatgtttca gagagtgaat tattttttta aacaaaaata
     2461 tctcaaaacg agataaagtg tacaacacta gaaaggataa aagaaaaatg ctcctaacgg
     2521 cagcacttat cttaatttta ttaacgaata tcgctatctt aactattatt gtcaaaatgg
     2581 ggaaagaata actgatattt tcggaattga tgaatacgct tatcagttgt gattttgatt
     2641 ttaactggct tttcatctaa atagtaagag aaattttctc gactagatgg atatacttca
     2701 gtatctgact taaatggcga tgactcccat tggtaatcta atggcatata ataattcggc
     2761 attgacaatc cataataatc atcagcttca ttctgcatgt cagcttcgta tttttgaaag
     2821 ggattgaagc cattatcgct tattagtttt ccatctttgt tgtaaagttc aattttttta
     2881 ataatgactg aaacattcga taagttactg atactaaaat catacatcca atcgtaacct
     2941 ttatctactc ttgaaatgta acaatcagat aattttatct taaccatgtt gtagtagata
     3001 gagtgaacaa gagcaatcac agcaacaatt agcgcaatga cgccgataat tgtattaaat
     3061 aattccattt ttattcttcc aatcgttttt attttaatta taccaaaata gaaaggacac
     3121 atatgaacga aatagaaaac aaactagaag aacttgaaga aatggtaata aacatggatg
     3181 aagtagatgt agtgattcca tggaagatag caaaaaacct gctacaaaga gcaggttact
     3241 tatcagaaga ggaacatcgc ctactaagtt ggagactcgg aaaatcaaaa tatgcaggca
     3301 aacgttccga aaaagtccgc aatttgctag agggacttag gaatagtgga agttccgaga
     3361 atagctgata attttaattc tgttgtttgg tcattgtgca tgaaaatgag agtttcattt
     3421 ttgcgattag gctcaatcca atgatcaata acaaagtctc cgacaagact atgtaaaata
     3481 acagtttcaa aatcatcaat actattcaat agaggagtta attcttctaa attcatttag
     3541 ttaccctcct tcctaatagg ataactacat tatacaacag aaaggaagca catgagacca
     3601 aaacgatatc cgtatagcgg agagaaaaag agagcctatc ataagataga ccctgaactg
     3661 ataaaaaccg gtaaagttga ttgcatcaat ctcccttaag tacgccaagc tctaacaatg
     3721 catttgtcat agctgcgata gtagatttag aggttgactt agagacatac tccaaaatat
     3781 taacgatatg ctgagcttgc ttttgtgtaa taggtgcatt catttgatta agttccgcaa
     3841 cgacaaattc aactaattgg ttgtcaacat tgaaattttg gttgatatgt tttgagacaa
     3901 ctttcataaa ttcttttgta tccataatta atctcctttc ttgcttattt gactaaacaa
     3961 gattagaaga gtagaggtct ctcgagagat cttgttgaat catacgaata ttatatcaag
     4021 actatattga aaaatcaata tattgtatat aaaaagttat caacaactac atgttgtgct
     4081 taggaggaat tatgtggggt aaaatcgaag ctctattaat tgagaaaaaa atgaccaaat
     4141 atgaactgtc acaaaaggct ggattgaacc aaaattgctt gattgatcta aagaaaggaa
     4201 gaaaaaaatc attgaaattt gatgatgtcg ttaaaattgc cgatgtctta ggtgtcagct
     4261 tagacgaatt tagatatcaa aaaaagtccg acggcaatcg gactctaaag aaattttaat
     4321 ttacttaatt ataacataag agagagggaa aaactatggc cattgaaata tttggacctg
     4381 agtttagaaa aaaactgctt gaagatttaa tcgctctaaa tatggaagcg ataaaaatag
     4441 cgcagaccaa aaacgccaag tctattgaat ggataaccat gaagcggcta gaaaaagaaa
     4501 ctggatgggg gcgaactaaa ttgacccagt ggagagaaca agggaaattt aactttaaaa
     4561 ggtcatcaga aaacgggaaa gtactatatg acctagcaga tgttaataga tttttacgga
     4621 ccagtggata tgaaaaagga gaaacaacat gaaattatta gattttattt ttgcaaaacc
     4681 aaaaaaacag gaaccgatta agcacgacac gcttagagca tcatctgaaa agcagtgggc
     4741 cgaatttgat gcctatatga ggaaacagta tggacgacaa gcttaatcag atattgatag
     4801 ccatgcgaaa ctaccgcaca aatggtgatg atagcaagta tttagaggat atggaggtca
     4861 ttttaaatga aaacaaaaat tgaaatcatg cgtgattttt ttaaagaaaa tcctgaatca
     4921 actcaacggc aagcctcaga aaagcttgga tttacggaaa atacagttaa acaatatatt
     4981 tggagagatg ctaagcgtgg ctactgtatt aaagacgaag aaggtcgtgt aacttatcta
     5041 aacattgaag atgaattatc gcttattaat gaatggaaaa gtgaaattag aagagaattg
     5101 attgaacagt tactatcagc taatcgacat gaaacgtcaa gcgaacaaat tcgtatgaac
     5161 gctaaaacaa tcaatcagat tttaggagaa atttaatgga aggtatgaaa aagtatatca
     5221 atggtcagat taaactaatt gatactattg aagaatgtgt caaagaaaaa tggcctgaat
     5281 ttgatgataa aaaagtacat aagatatctt tagctattta ccaaggatgg tcccttacag
     5341 atattaatag cacactcgaa gcgatagaaa tggacttgga tagaaaatga gaatttatgt
     5401 aaacaaaaaa ggtaaaccat ctgttgaatt tgagtttgaa gatcgacgcg gtggcatgtt
     5461 tgatacaaga ttaatgttaa aagaatcacc actcaaagaa gaatttaaag ccgatatgta
     5521 caaggcaatt gatgatgttt taaaaaaata cgaagacatt tttgatactc ctatttttaa
     5581 agaattaata attgggaaag aagaagatat tagaaaaatg attgattacg atgataaatt
     5641 taccgaactt tttggaggga ttagacattg aagattacta aagcgacaga aattacaaaa
     5701 acccataatt ggcgcatatt aatctatggt aaacccggaa acgggaaaac ttacttaact
     5761 aattatttaa aaggcaagac actgatttta gacatggacc attcgtctaa aacgattgcc
     5821 ggaaacgaaa acattgatat tatccaattt gacaggacgc accctagcga ctttatgacc
     5881 gaattcttga cagaactacc agaacttatc aaagaatatg acaatttagt cattgataat
     5941 ataacaagtt ggcaatcaga ctggtttatc gaacaaggtc gtaaatccaa aaatggaatc
     6001 acaaacgaat tgcaacaata caacatgtgg accaattact atttacgagt attgactacc
     6061 atttacagcc aacctactaa tatttttgtg actgcttggg aatcaacgca agatttaacg
     6121 ctcgagagcg gacaaattat cacgcaatac gtgccagata tccgcaaaca agtcctaagc
     6181 caaacgctag gtttaaccga tgttgtcgga cgtattcaag taaatccaaa aacgggcggg
     6241 catggaattt tgttgcaggg cagcgacgga ctatatgcaa aaaataggct tgataatagg
     6301 accgtttgta aggcggaaga gttgtttaat ttcgaaggga gtgatgcgta acggtatacc
     6361 atttacacga atatcaaaca gaacttataa atgaggcaag aagacatatt ttaaagcata
     6421 atgtgatgat tgttagtcca cctggaagtg gtaagtcagt agtcatttct gatattgcta
     6481 agtcagcgac tcaaaaaaac ggacacgttt tattcttggt ccatcgcaaa gaattaattg
     6541 accaaatcac taatagtttt aaattccatg gaattgacat gaataaagtg gatttaatga
     6601 cagttggtaa agctaaaaac cgcttggata aattaacaaa accaacctta attatcacag
     6661 atgagggtca tcatgggaaa gctagtacct accaaataat ctatgaatac ttttcagacg
     6721 tgccgaggat tggttttact gccacacctt ggcgtctatc aggcgacggt tttacagaca
     6781 cttacgatgt tatggttctt ggtaaaacgg tcgagtggct tatcaataat aataaacttg
     6841 caccatatga ttattacagt gttctatcaa ttgatactgc gaaattaaaa gtacaaaacg
     6901 gagattactc caataaatcg attgacgaat catttggtaa aaagattttt ggtgatgtag
     6961 ttcaagaata tataaaaaaa gcgaacggtc agaaagctat tttatacgct cactcggtag
     7021 aagcatcgca ggcatttgct aaagaattcc aatctatggg aattaatgca atacacgcag
     7081 atgcaaaaac gcctaaagcc aaacgggata aaatcatgaa agatttccgt gacggtaaga
     7141 tacaagttat ctgtaacgtt gatttgatat cagaaggttt cgatgtccca gattgtacag
     7201 taactattct ttgtagacct acaaaatcat tagtattatt tttgcaacaa tctatgcggt
     7261 cgatgagata tcaacctaat aaaaaagcca tcattttaga tcacgtagga aattggaata
     7321 ttcacggctt acctgacaca ccgcatcatt gggagaatta tttccgagga gggtggaaga
     7381 agaagtcgaa taaaactaac acggtacacg caaaagaatg ttctgtgtgt tcggctttgt
     7441 ggccacttag tcaacagctc tgtgaattat gcaatcatga ttttggattg aaagaaaaac
     7501 aagagaaaga acgcatagag gcagaacttg aactcataaa acgtgagcgg tttagaatca
     7561 aacaacttgc taataagaag tttggtaaag atttaaaaac aaactgggaa attgcccaag
     7621 ctagagttaa agacgctggt aaaggaaaac cattatataa acttatctat ttctacttaa
     7681 aaactgattg ggtagaaaca aacgttaatg aacttgccga agtaacaggc aagtcagaaa
     7741 aagaaatata tagcgcctac aattggctaa aaaagaaatt aagaggataa aaacatggca
     7801 ggatttacaa cagatttttc agaagttaaa gaacacgcag aattcaaaga acaaccatac
     7861 gaaatgattg tctatgatgc atatgaagca gtaaatgaac gtaacggcaa aaaacgtgtt
     7921 gttattgact acgttgttcg aaacgatatc aagcaagaaa tgcaaaacta ccacttatgg
     7981 gatgagcaat atcccaactc acaaactggg aagtatcata tcggcatctt aatgggtaaa
     8041 gcaaaagcac ttggtatcaa agaggggcaa cactacgata gttttgaagc gtttttaaac
     8101 gacttcaaag gacgcactgc aaaagtaacc gttaaacttg acgaatataa cggaaataaa
     8161 tacccgaaag ttcgttacgc aaatcaaagc gatgtgccta acagctacca cgtatggaaa
     8221 gaaaaagcaa ctggatttac acaagcggag attgaagaag acgatctacc gttctaattt
     8281 agactggggg ataaatgaca tcaaatgaat ttattgaagc tttatcaaaa ttgacaaccg
     8341 aaaccgattg gggagaccca atcttcggcg agtcagtgct taaagctgaa ttacgaaaac
     8401 acttatttaa aattgtccca attgatcaca atgggtatat ccacaaactg ttttattcag
     8461 aaatggttaa agatgaagat gtcatgtatt ttgtgtcaga tggacgaaaa acttatcgct
     8521 ttttatttgg agatacaatt ctaaagactg ataaacaagg caatgaatat ctcacatact
     8581 ccgttgaaaa taattttcca ccatttgcaa aactagttat cgactacatt ctaggtgctt
     8641 acacgttttt tgagaataaa ctttatgaca ttcgatataa gcaatttaaa ttgattgatg
     8701 attttacact tcagactaag tatggtttca aagactctgg tcacatttta gagatactac
     8761 aaggtatcca caaaacatta aacatccaac caatcaatta tattgaacca tatcagattg
     8821 cttgcaagga tttcataatc gaccttgaaa attctgaaat cattaaccaa ccgcctttgc
     8881 aaaacgtatc ttattttaag tattacgaag tagactacaa aacagcaata aacagtaagt
     8941 ctattgcaga agaatatctt gagtacgtta ttgcagatag caattcgtta aacaatgcaa
     9001 tactacaatc ttattttatc gcccaagtag cgtgtggtgt tagacctaaa accaacttct
     9061 tcatctcaaa atctggagta aggactggta aagggttaag gcatatagct ttatctggtc
     9121 tattcaataa gattgatgtt gagctagata cattaaaaag taatggattt gaagcgttac
     9181 aggcgtgggc gatgttctcg ggtggagaaa tggctctagc gacggaacag ggagatattc
     9241 aaggcaatgc aatggagcgt gtacttaaaa ttattgcaac agagaaaaca cacgttgcac
     9301 gagcaattgg gcaaaatcag tcaatggtta atttaacgag tgttctgtgt attgacacca
     9361 accgtactgt tgcgctgtcg gatgaaatga atggacgaaa ggttttaatt cagtttaaag
     9421 atagaccaaa aactgaaact gattatgaaa gagagagcat attcaggaaa tattggctag
     9481 catttactga ctgtgataaa aatccaaaaa tcgatggatg tatcggtttt ctgctaaatt
     9541 cactcgagcg tttccaaaaa attggtaaat ggtatcaatg gaaagatgtt gaagtattta
     9601 atgatatcga tttagacgaa tttcaagttg ctttaataaa tgcattacaa gaagttgatt
     9661 ttgtacagcg aactgataac aaagaagtta ttgacttatc attacaagtt tacggaaaaa
     9721 gcaatcatgc attaagtaaa gccatatctg aaattggtgt acgtagcagg tcgaagaaag
     9781 ttaacgggaa aacagtcaga gggtatgaaa tcgaaaataa aacacgtttt gataaatata
     9841 tccttt
//
LOCUS       DATWEK010000050         9445 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.050, whole genome shotgun sequence.
ACCESSION   DATWEK010000050 DATWEK010000000
VERSION     DATWEK010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9445
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.050"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            88..1008
                     /gene="lmb"
                     /locus_tag="VCR92_001635"
     CDS             88..1008
                     /gene="lmb"
                     /locus_tag="VCR92_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/laminin-binding adhesin Lmb"
                     /protein_id="HEP4268686.1"
                     /translation="MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYA
                     MTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNL
                     KKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKE
                     LGRLDPKHKDSYTKKAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGL
                     KQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKT
                     LSPLEAAPSGNKTYLENLRANLEVLYQQLK"
     gene            1021..3498
                     /locus_tag="VCR92_001636"
     CDS             1021..3498
                     /locus_tag="VCR92_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEP4268687.1"
                     /translation="MKKTYGYIGSVAAILLATHIGSYQLGKHHMGSATKDNQIAYIDD
                     SKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAII
                     SEELLMTDPNYHFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVA
                     KGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVP
                     HGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPAPAPGRRKAPIPDVTP
                     NPGQGHQPDNGGYHPAPPRPNDASQNKHQRDEFKGKTFKELLDQLHRLDLKYRHVEED
                     GLIFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDNDSGSDH
                     SKPSDKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHF
                     HYIGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGK
                     VGYMMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSS
                     LPMHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDVWSKPG
                     HEESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKE
                     TFVWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQ
                     ADKSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIF
                     QPEGVQFYNKNGELVTYDIKTLQQINP"
     gene            3667..3867
                     /locus_tag="VCR92_001637"
     CDS             3667..3867
                     /locus_tag="VCR92_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEP4268688.1"
                     /translation="MSEEKLKSKIEQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGK
                     ELADDAKEAVEGAVDAVKEKLK"
     gene            complement(3949..4575)
                     /locus_tag="VCR92_001638"
     CDS             complement(3949..4575)
                     /locus_tag="VCR92_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4268689.1"
                     /translation="MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTS
                     LSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYP
                     SQDLRDAFGIQEKWLKRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQA
                     SVWKSLLEIVKDRNLGLIIISHEFDMLEKLCDACYMIEENRTQLFKHT"
     gene            complement(4559..5362)
                     /locus_tag="VCR92_001639"
     CDS             complement(4559..5362)
                     /locus_tag="VCR92_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4268690.1"
                     /translation="MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLA
                     IIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIKQLRGKEMTLIPQSVN
                     YLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGNLYPFQLSGGMLRRVLFTTC
                     ISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITI
                     FKEGKAIETAPASFFSGGGEQLQTEFARRLWRTLPQQDFLKGVTHDLRG"
     gene            complement(5374..6195)
                     /locus_tag="VCR92_001640"
     CDS             complement(5374..6195)
                     /locus_tag="VCR92_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4268691.1"
                     /translation="MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNASLRNL
                     APSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVSLATVFGVLAGLGNSLID
                     KIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKN
                     KAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAE
                     QPSVGIILSEAAKHISLGNWWLVVFPGLYLILVVNAFDTIGESLKKLFYPQTDHF"
     gene            complement(6192..7169)
                     /locus_tag="VCR92_001641"
     CDS             complement(6192..7169)
                     /locus_tag="VCR92_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4268692.1"
                     /translation="MKRTTIIIIWKIIRCVTLIFGVSVLTFVLLKQSPVDPVMASVNY
                     DTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGHLGTSLVYRQPVSDIIRSRAGA
                     SFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVVRWFSYLQISVPTFWIGLIFLLIF
                     SVQLGWFPIGISSPIGTLSQDITLADRVKHLMLPVFTLSILGIANVTLHTRTKMMSVL
                     SSEYVLFARARGETQWQIFKHHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGL
                     GSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKV"
     gene            complement(7282..8910)
                     /locus_tag="VCR92_001642"
     CDS             complement(7282..8910)
                     /locus_tag="VCR92_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEP4268693.1"
                     /translation="MSKYLKYFSIITLFLTGLILVACQQQKPQTKERQRKQRPKDELV
                     VSMGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIKGELAKTYHLSEDGLTWSF
                     DLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGKNQINIHLTEAHS
                     TFTAQLTEIPIVPKKHYNDKYKSNPIGSGPYMVKEYKAGEQAIFVRNPYWHGKKPYFK
                     KWTWVLLDENTALAALESGDVDMIYATPELADKKVKGTRLLDIPSNDVRGLSLPYVKK
                     GVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKPAYSIIDKTPFWN
                     PKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTNDQLRANLAVEVA
                     EQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHHPSLAGKGWTNIT
                     FYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPNVWLVSLNHTYIG
                     DKRINIGKQGVHSHGHDWSLLTNIAEWTWDESTK"
BASE COUNT         3107 a         1823 c         1872 g         2643 t
ORIGIN      
        1 aagatggtag ttgccattga caaagcattg ataaaggagt aaaattaact ggttaataac
       61 tggttaaatt ataattgagg aggtactatg aaaaaaggtt tttttctcat ggctatggtc
      121 gtgagtttag taatgatagc agggtgtgat aagtcagcaa accccaaaca gcctacgcaa
      181 ggcatgtcag ttgtaaccag cttttaccca atgtatgcga tgacaaaaga agtatctgga
      241 gacctcaatg atgtgaggat gatccaatca ggtgcaggca ttcattcctt tgaaccgtct
      301 gtaaatgatg tggcagctat ttatgacgcg gatttgtttg tttaccattc acatacctta
      361 gaagcttggg caagggatct agaccctaat ttaaaaaaat caaaggttga tgtgtttgaa
      421 gcgtcaaaac ctttgacact agatagagtc aaagggctag aagatatgga agtcacacaa
      481 ggcattgacc ctgcgacact ttatgaccca catacctgga cggatcccgt tttagctggt
      541 gaggaagctg ttaatatcgc taaagagcta ggacgtttgg atcctaaaca caaagacagt
      601 tacactaaaa aggctaaggc tttcaaaaaa gaagcagagc aactaactga agaatacact
      661 caaaaattta aaaaggtgcg ctcaaaaaca ttcgtgacgc agcacacggc attttcttat
      721 ctggctaaac gattcggctt gaaacaactt ggtatctcgg gtatttctcc agagcaagag
      781 ccctctcctc gccaattgaa agaaattcaa gactttgtca aagaatacaa cgtcaagact
      841 atttttgcag aagacaatgt caatcccaaa attgctcatg ctattgcgaa atcaacagga
      901 gctaaagtaa agacattaag tccacttgaa gctgctccaa gcggaaacaa gacatatcta
      961 gaaaatctta gagcaaattt ggaagtgctc tatcaacagt tgaagtaaag gagattatta
     1021 gtgaagaaaa catatggtta tatcggctca gttgctgcca ttttactagc tactcatatt
     1081 ggaagttacc aacttggtaa gcatcatatg ggttcagcaa caaaggacaa tcaaattgcc
     1141 tatattgatg atagcaaagg taaggcaaaa gcccctaaaa caaacaaaac gatggatcaa
     1201 atcagtgctg aagaaggcat ctctgctgaa cagatcgtgg tcaaaattac tgaccaaggc
     1261 tatgtgacct cacacggtga ccattatcat ttttacaatg ggaaagttcc ttatgatgcg
     1321 attattagtg aagagttgtt gatgacggat cctaattacc attttaaaca atcagacgtt
     1381 atcaatgaaa tcttagacgg ttacgttatt aaagtcaatg gcaactatta tgtttacctc
     1441 aagccaggta gtaagcgcaa aaacattcga accaaacaac aaattgctga gcaagtagcc
     1501 aaaggaacta aagaagctaa agaaaaaggt ttagctcaag tggcccatct cagtaaagaa
     1561 gaagttgcgg cagtcaatga agcaaaaaga caaggacgct atactacaga cgatggctat
     1621 atttttagtc cgacagatat cattgatgat ttaggagatg cttatttagt acctcatggt
     1681 aatcactatc attatattcc taaaaaggat ttgtctccaa gtgagctagc tgctgcacaa
     1741 gcctactgga gtcaaaaaca aggtcgaggt gctagaccgt ctgattaccg cccgacacca
     1801 gccccagccc caggtcgtag gaaagcccca attcctgatg tgacgcctaa ccctggacaa
     1861 ggtcatcagc cagataacgg tggctatcat ccagcgcctc ctaggccaaa tgatgcgtca
     1921 caaaacaaac accaaagaga tgagtttaaa ggaaaaacct ttaaggaact tttagatcaa
     1981 ctacaccgtc ttgatttgaa ataccgtcat gtggaagaag atgggttgat ttttgaaccg
     2041 actcaagtga tcaaatcaaa cgcttttggg tatgtggtgc ctcatggaga tcattatcat
     2101 attatcccaa gaagtcagtt atcacctctt gaaatggaat tagcagatcg gtacttagcc
     2161 ggccaaactg aggacaatga ctcaggttca gatcactcaa aaccatcaga taaagaagtg
     2221 acacatacct ttcttggtca tcgcatcaaa gcttacggaa aaggcttaga tggtaaacca
     2281 tatgatacga gtgatgctta tgtttttagt aaagaatcca ttcattcagt ggataaatca
     2341 ggagttacag ctaaacacgg agatcatttc cactatatag gatttggaga acttgaacaa
     2401 tatgagttgg atgaggtcgc taactgggtg aaagcaaaag gtcaagctga tgagcttgct
     2461 gctgctttgg atcaggaaca aggcaaagaa aaaccactct ttgacactaa aaaagtgagt
     2521 cgcaaagtaa caaaagatgg taaagtgggc tatatgatgc caaaagatgg caaggactat
     2581 ttctatgctc gtgatcaact tgatttgact cagattgcct ttgccgaaca agaactaatg
     2641 cttaaagata agaagcatta ccgttatgac attgttgaca caggtattga gccacgactt
     2701 gctgtagatg tgtcaagtct gccgatgcat gctggtaatg ctacttacga tactggaagt
     2761 tcgtttgtta tccctcatat tgatcatatc catgtcgttc cgtattcatg gttgacgcgc
     2821 gatcagattg caacaatcaa gtatgtgatg caacaccccg aagttcgtcc ggatgtatgg
     2881 tctaagccag ggcatgaaga gtcaggttcg gtcattccaa atgttacgcc tcttgataaa
     2941 cgtgctggta tgccaaactg gcaaattatc cattctgctg aagaagttca aaaagcccta
     3001 gcagaaggtc gttttgcaac accagacggc tatattttcg atccacgaga tgttttggcc
     3061 aaagaaactt ttgtatggaa agatggctcc tttagcatcc caagagcaga tggcagttca
     3121 ttgagaacca ttaataaatc tgatctatcc caagctgagt ggcaacaagc tcaagagtta
     3181 ttggcaaaga aaaatgctgg tgatgctact gatacggata aacccaaaga aaagcaacag
     3241 gcagataaga gcaatgaaaa ccaacagcca agtgaagcca gtaaagaaga agaaaaagaa
     3301 tcagatgact ttatagacag tttaccagac tatggtctag atagagcaac cctagaagat
     3361 catatcaatc aattagcaca aaaagctaat attgatccta agtatctcat tttccaacca
     3421 gaaggtgtcc aattttataa taaaaatggt gaattggtaa cttatgatat caagacactt
     3481 caacaaataa acccttaacc aaaagaagat ctcattgtta aagcactgct ttgtcaaagc
     3541 aagttaccgt gattttgaag tcattttatg taacgagtag tgataaaagt tggataatag
     3601 cggttttctt ttgcaaagaa atggtatcca tgttagaata ataaaaaaaa gaggaggatt
     3661 ctaatcatgt cagaagaaaa attaaaatca aaaattgagc aagcatctgg tggcctaaaa
     3721 gaaggtgctg gtaagttgac aggtgataaa gagctagaag caaaaggatt tgttgaaaaa
     3781 acaattgcta aaggcaaaga acttgcagac gatgcaaaag aagcggttga aggtgctgta
     3841 gatgccgtta aggaaaaatt aaaataatta aaaaaaccag ctgtaagctg gtttttttaa
     3901 tggtgtgatt ttgttaggaa aagactcaat aggtaataac cgtaggtgtt aggtatgctt
     3961 gaacagttga gtacgattct cttcaatcat atagcacgcg tcacaaagtt tttctaacat
     4021 atcaaactca tgactaataa tgatgagacc taaatttcta tcctttacaa tctccaacag
     4081 gcttttccat acactagctt gtgtaatgct atccaacata gtagtcattt catctgcaat
     4141 aaggtatttc gtctctggat gtaatgaacg cacaatcgaa aagcgttgca attcccctcc
     4201 cgagagttca ctagggcgac gctttagcca tttttcttga atgccaaaag catctcgcaa
     4261 atcttgactt ggatagtagg cttcttccaa actttttttc ataggccata aaggattcat
     4321 ggtttgttca ggatgttgtt ggataagttg tacaggtcta aatgctttgt taggcaaatg
     4381 actgccatca actaatactt caccagattt aggctgcaaa aaaccggcaa gcactctgga
     4441 taaacttgtt tttccacacc cactttgtcc aaatatccct aagatttgac caggtgctac
     4501 ctctaaatca atctccttaa aaagccattg atctttttta tgataaaagc caagcttttt
     4561 agcctctaag gtcatgagta actcctttca aaaagtcttg ctgagggagt gtgcgccata
     4621 aacgtctcgc aaattctgtt tgtaattgct ccccacctcc gctaaaaaag ctagctgggg
     4681 ctgtttcaat agcttttccc tctttaaaaa tagttatacg atccgcaatt tgactagctg
     4741 ctacaatatc atgagtgata aatatgacgc ttattccttt atctgcaaag gagcgtagtt
     4801 gatctaaaac catttgcaga gcatctggat gtaatccagg ggtgggctca tccgcaataa
     4861 tcaaagaaac cgtatcacta atacacgttg taaacaaaac acgtcggagc attccgccag
     4921 aaagttggaa aggatacaag ttaccatcac tttcttttaa accaaactgt tgaaacaatc
     4981 cttcttgagt agccttagca ttttctgaga tacccaagcg cacctgatgc ttgactttca
     5041 tagatggatc taaataatta acggattgtg gaatcaacgt catttctttt cctcgcaact
     5101 gtttgatgcg tttagaagtt agtgattgac cacgataaat catatctcct gttacagctg
     5161 catttttagg aagaatatcc ataatagcat gtgctaataa actcttgcct gaaccactag
     5221 cacctataat agctaataac tcaccttttt taacttctaa attcagcgct tggatcggtg
     5281 tggattgaaa tggttttaaa aatcttccgt attgagtgaa ggtgatggag aggtctttaa
     5341 tgcttaataa tgtttctgtc atatctctac ctcctaaaaa tgatccgttt gagggtaaaa
     5401 gagtttcttt aaagattctc cgatagtatc aaaggcattg acaactaaaa taagataaag
     5461 gcctggaaaa accaccaacc accaattgcc aagagagata tgcttagctg cttctgacag
     5521 aatgatacca accgaaggtt gttcggcaga aaggccaaat cctaagaaag tcatggatgc
     5581 ttcatgcaag atgacgtgcg gaaataagag gataaaccca atgaaaattt gagaagcaat
     5641 caaaggcagg atatgatgcc tcacaatata ataaggcgtt tttcccatgc ttttagagag
     5701 ctggacaaag gctttattct ttagatcata gacttcattg cggataagcc ttgctagaga
     5761 gggccaatgg gtaacagccg ttgcaatgat aaccccttga gcccctttac caacaacaaa
     5821 agaaatgaga atcataaaaa tcaaatgagg cataccaata aacaaatcaa ccaaccaggc
     5881 tattatttta tcaataaggc tatttcctag acctgcaagc actccaaaaa cggtcgcaag
     5941 agagactccc ataagggcac ctaataagcc gacttgtaaa gagaaataaa gccctttaat
     6001 cgttctgacg aacatatccc tacctaaacc atctgtccca aaaagatggt ttaaggaagg
     6061 agcgaggttg cgtaaagatg cattggtttc caaaggcgtc ctatagaaat aaaggtttaa
     6121 ggctagaata ctaagaatga gagaaatggc gatacctagt tgccataaaa ccatcgttcg
     6181 acgtttcaat atcatacttt tctccttaac tgtggattga tgatgctatt taaaatatcc
     6241 gcaataagat tgcccgcaaa aacaaataat gtccctatca tcacgatagc tagaaggagc
     6301 ggtgtatcac ttttaagtcc tgcttcagtg agggtagacc ctaagccagg atatgagaaa
     6361 acttgctcag caagaacaga tcctccaaac aattctccaa aataggaaaa atgcagtgta
     6421 atagctggta cgatagcatt tctaaggcaa tgatgtttaa aaatttgcca ctgtgtttcc
     6481 ccacgcgctc tggcaaataa gacatattca ctagaaagca ccgacatcat tttagttctc
     6541 gtatgaaggg tgacattggc aatgcctaga atacttaacg tgaaaacagg taacataagg
     6601 tgcttaaccc gatcagctaa cgtaatatct tgactcaaag tgcctatcgg ggaagaaata
     6661 ccaatcggga accaccccag ctggacagaa aagattaata aaaaaatgag gccaatccaa
     6721 aacgttggta ctgatatctg aaggtaagaa aaccacctga caactcgatc aagtaatttc
     6781 ccttgatgga aagcggataa cgttcctaag ataaatccaa taagacccga taagatccaa
     6841 gagagtccca taagtatgaa agaagcacct gcccgtgatc taataatatc actaacaggt
     6901 tgccgataaa cgagcgaggt ccctaaatgt ccctgtatca catttttcaa ccaaataaaa
     6961 tactggacta gagctggctt atccaagcca tagtggtgag caatcgcttt gtactgagca
     7021 ggggttagtg atgtgtcata attgacactt gccatgactg gatctactgg agattgtttt
     7081 aacaaaacga aggtcaaaac agatacccca aaaataagcg tgacacatct gatgattttc
     7141 cagatgataa taatggtagt acgtttcaca atgaaatctc cttaatcgat aagaaaagga
     7201 gccgaggaaa cgatcagcac agttttgtgt atcttgtttt ctcagactcc aaacttaaag
     7261 tcgctgtatt aactaaacgc gttacttagt tgattcatcc caagtccact cggcaatgtt
     7321 agtcaataat gaccaatcat gaccatgact gtggacgccc tgtttaccta tattgatacg
     7381 tttatcacca atataagtat ggttaaggct caccaaccat acatttggca aatctccaag
     7441 agtagaagca cctgttttgc catcccactg cgctaacttc caatattcgt tagctttgtc
     7501 aaggtcagaa gatgtcattg ctttgtcaag gtacttagtc acggtaggat tgttataaaa
     7561 cgtaatattg gtccaacctt tacctgctag gcttggatga tgtgattcat aaaattgctg
     7621 cgcgtgatga cgtcctccgg cataaagtaa ggctgagtca tgtgacttcg ttgccatttc
     7681 atcccagtta ctagctttga gtttaatagt aatccctagg gctttggctt gctctgctac
     7741 ttcaacggct aagttcgctc gcaattgatc attagtaggg tagtacagat caaacgctgc
     7801 atcaaggtca ccttttttac ggctaccgtc tgcttgttct ttccatccag cttttgtcaa
     7861 caattgctta gctttagcta ctttattatc tttaatggct gtttttggat tccaaaatgg
     7921 tgttttatca ataattgaat aagctggttt accataacca tttaaaaccg tatcgagaac
     7981 tttttgccta tttaaaccaa tagtcaaggc ttttcggatt gctggatcac tagtgacatc
     8041 atttcctaca ggataaccat caggagaatc agtgatgacg ccttttttca cataaggtaa
     8101 tgataagccg cgcacatcat ttgatggaat atcaaggagg cgggtgcctt tgactttttt
     8161 atcagcaagt tctggcgttg cgtagatcat atcaacatca ccagattcta aagctgctag
     8221 tgctgtgttt tcatcaagta agacccaagt ccatttttta aagtatggtt ttttcccatg
     8281 ccaataaggg ttacgaacaa aaatagcttg ttctccagcc ttatattctt ttaccatgta
     8341 aggtcctgaa ccgataggat tgctcttata cttatcattg taatgttttt tagggacgat
     8401 tgggatttca gtcaactgtg ctgtaaatgt cgaatgcgcc tcagtcaaat ggatattgat
     8461 ctgatttttc ccaactactt caacgttctt gatgaaggtt agatcccaag cctttccatc
     8521 tgctttcaac atatcataag taaacttaac atcatcagca gtaacaggct caccatttga
     8581 gaatttaaaa tcatcatgca agtcaaacga ccaagtcagc ccatcttcag agagatggta
     8641 tgttttagca agctctcctt ttatatctag ttcaggagaa cgtttcaata gagtgctatg
     8701 agtgatattc ccttcattgt ggactccata acggtccttt ggatcgaatt catgagggag
     8761 ctttgccccc atagaaacga caagttcgtc ttttggacgt tgtttgcgct gacgttcttt
     8821 tgtttgaggc ttttgttgtt gacatgcaac taaaataagc ccagtcaaaa ataacgtgat
     8881 aatagagaag tattttaggt attttgacac aatcaaatct ccttatttct aattaataaa
     8941 taataatagt aacgactcca tctcattata gcaataaaca aataggaggg caattgttta
     9001 actggttaat tagaattttt gttattttta ggaagatact caggactttt ttataagttg
     9061 atgtattaac aaaagataaa gaggtttcat gacttatttt agattaaaaa aagaattaaa
     9121 ctgatcacta agaaataaag gaattgtagt ttacgaaggg aatcaaaaac ttcagatagc
     9181 cattaataca ggtaaaaata acagtgaaaa aagtcttttt tgatactttt cttgaggtgg
     9241 ttcgggcggc agcgactttc tccacaggaa aaaacatctg ttttggtctt ggcttacttc
     9301 gttcgcagaa ataggaaatc gggtatcaca ttagcagagt agttcatgtt ttttgagcat
     9361 cacactggat ctgtctacgt tctaaaagct ttcttcattt ttgtatcata ccccctacaa
     9421 gtagaaaaag tataacaaag aaaat
//
LOCUS       DATWEK010000051         9198 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.051, whole genome shotgun sequence.
ACCESSION   DATWEK010000051 DATWEK010000000
VERSION     DATWEK010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9198
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.051"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..601
                     /locus_tag="VCR92_001643"
     CDS             <1..601
                     /locus_tag="VCR92_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268694.1"
                     /translation="ENMRVEFSNYLHDDVLQNIIAIKNLLSLENSNITHGFIVNELND
                     LVSGIRDEMDTYYPIVPANQTMKENIQSLFDDIVKSRKSNTLLYFNCSDNMVVPSPYG
                     DIVYRFIKELINNAIKYGDGKDIRLSLTIQSDIIIIEESNQVVEKVHSISYGRGLKSF
                     QETLAAFDGDLELQMDTKQFTIRILLPIDWKLCYEDFIN"
     gene            582..1187
                     /locus_tag="VCR92_001644"
     CDS             582..1187
                     /locus_tag="VCR92_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP4268695.1"
                     /translation="MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLS
                     KYDITLLDINLTNISKENGLEIAKELIQSTPHLKVVMLTGYVKSIYRERAKKVGAYGF
                     VDKNIDPKQLISILKKVDSGKKYFEQIESQDYVESLTDQEIAILNLSKKGFSIKEIEE
                     TLQISRRTVFNHLTHIYSKLLVNNKQEAIYKAEQLGYFMDF"
     gene            complement(1739..3319)
                     /locus_tag="VCR92_001645"
     CDS             complement(1739..3319)
                     /locus_tag="VCR92_001645"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEP4268696.1"
                     /translation="MAEKTTSLRQALWHSADQLRGQMDANDYKNYLLGLIFYKHLSDK
                     LLFAVCDNLEEHFNTFTDAQKIFENAYQDEGLKDDLISVVTGDLGYFIEPTLTFEKLI
                     QDVYHNTFQLESLAQGFRDIEQSGEDFENLFEDIDLYSKKLGSTPQKQNQTISNVMKT
                     LNEIDFEAVDGDTLGDAYEYLIGEFASESGKKAGEFYTPQAVSHLMTQIVFLGWEDQK
                     GMTLYDPAMGSGSLLLNAKKYSNQSDTVSYYGQEINTSTYNLARMNMMLHGVAIENQH
                     LSNADTLDADWPTDEPTNFDGVLMNPPYSLKWSATAGFLTDPRFSSYGVLAPKSKADF
                     AFLLHGFYHLKNTGTMAIVLPHGVLFRGAAEGKIRQKLLEQGAIDTIIGLPSNIFYNT
                     SIPTTIIILKKNRTNKDVFFIDASKEFDKGKNQNTMTDSHIKKILDAYKSRDNSDKFS
                     YLASFDEIIENDYNLNIPRYVDTFEEVPVKPLPELAKQLSDIDQEIAKTNAKLDQLMK
                     QLVGTTKEAQDELDTFRN"
     gene            complement(3332..4519)
                     /locus_tag="VCR92_001646"
     CDS             complement(3332..4519)
                     /locus_tag="VCR92_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEP4268697.1"
                     /translation="MTKSKRPQYRFDSFEGEWEEKKLGEISNIVRGASPRPIQDPKWF
                     DAKSDIGWLRISDVTEQEGRITYLQQRISELGQEKTRVLKDPHLLLSIAATVGKPVIN
                     YVKTGVHDGFLVFLDPKFNREFMFQWLDMFRPYWNKYGQPGSQVNLNSEIIRNQVINL
                     PSLPEQEAIGELFQTVDQLIQLQRQKLAILKEQKQTFLRKMFPAQGQKVPEIRLQGFD
                     GEWEEKELGDIVQITMGQSPSSQNYTTNPSDYILVQGNADIKNGYVFPRVWTTQITKQ
                     ADKGDIILSVRAPVGDVGKTNYHVIIGRGVAAIKGNEFIFQILKYLKEIGYWKRISTG
                     STFDSISSSDIKYAKIQIPSLSEQEAIGNFFQTLDQQIAQSEEKLTELKALKQTLLNR
                     LFV"
     gene            complement(4532..7510)
                     /locus_tag="VCR92_001647"
     CDS             complement(4532..7510)
                     /locus_tag="VCR92_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEP4268698.1"
                     /translation="MGNQTKTELELEKELIHLLETGESQWTYRKELKTEDALWDNFFK
                     ILAQNNTQYLNEEPLTASEKEQIKNQLNFVNYYEAAKWLAGENGIAKVQVQREDAKLG
                     TIRLEVVKADNVAGGTSVYEIANQVAFSGSRDRRGDVTLLINGLPMIQIELKSQNHQC
                     IEAFNQVKKYDKEGQFRGIFSTLQMFVVSNKTDTRYIAAAKENKLNPNFLTQWVDQNN
                     KPQKDLFAFAKEVLSIPRAHQMVMTYSVIDDDKKALILLRPYQIHAIEAVAEASRHRK
                     SGYIWHTTGSGKTLTSYKVARNILQIPAVEKSIFVIDRKDLDNQTASAFQSYAQNDIF
                     DVDETEDTRQLIKNLESSDRRVVATTIQKLNAMISQMESYDTPKFKKLKERLAHLNVV
                     FVVDECHRAVTPERQRYLTNTFRNSRWYGFTGTPIFVENKRAQLGDLAQTTEQQYGKC
                     LHQYTVKEAIHDKAVLGFQVEYKTTIPDMPEDSIPEEAYDHEEHMLAVLDSIINQSRK
                     KLGFNNGIGQTFEGLLTVKSIARAQAYYDLMKKVKAGETDLVISKKVKEKLPDFPKVA
                     ITYSITENDNASISRQDKMTKNLEDYNHLFGTNFTIDNLQGYNRDLNDRLARKKDKFK
                     DRHEQLDLVIVVDRLLTGFDAPCLSTIFIDRQPMKPQHIIQAFSRTNRIFESRKHYGQ
                     VVTFQTPLRFKEAVDTALSLYSNGGQSEVLAPSWEEEKARFFEKVTVLKNIVPDPDAF
                     PTIESAQTAFLKQYAKAFQAFDKLYASVQVYSDFNETLLSEVGLSDEVIDTYKGTYQN
                     VIAEIRKRREDDEAIPEINIDYELESVQMDDINYHYILTLIQAFVDQEQEALQERLND
                     NPMDQYIQDLAKSNPAMADSLAELWQDIQKEPKAYEGKSIAYELDNLIGDKIQRAIKH
                     FADQWKADPDKLAFVATNYHSANSTKQVGISTLKESLDYQAYKEKQGDSAMNKLKYKS
                     QFERELVQFIRDQIQPLKGH"
     gene            7791..8933
                     /locus_tag="VCR92_001648"
     CDS             7791..8933
                     /locus_tag="VCR92_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEP4268699.1"
                     /translation="MTINRVLKDDNLLQYTEKEFIEDMKILVAIDSFKGSVTSPELNT
                     SVAQALLSVDKQLVIETRAIADGGEGSLAALSQTVAGRWHQVKTIDLLRRPIKVAYYR
                     HAKQAFIESASIIGIDKITPNSVTYAQATSYGLGLAVKDAIQKGATQIEIMLGGTGTS
                     DGGKGFLESLNYDFMTGRSYLDTLASPVTLLGLTDVTNPYHGPQGFAAVFGPQKGGSL
                     SQIEETDQIASNFAKKVFYQKTIDLQTIPGSGAAGGLGGAIVLLGGTLTSGFSRIAEL
                     LNLDNSLQSCDLVITGEGCLDTQSQSGKVPVAIARMAKKYQVPTIALCGSVKIETGLA
                     AEDFLAVFSIQQQPISLEAAIDKTTTLSNIKILVANLMLLIAQFNK"
BASE COUNT         2802 a         1578 c         1763 g         3055 t
ORIGIN      
        1 ggaaaacatg agagtggagt tctcaaatta tttgcatgat gatgttttac aaaatatcat
       61 agcgataaaa aacttgcttt ctctagaaaa tagtaatata acacatggtt ttattgttaa
      121 tgagttgaat gatttagttt ctggtatcag agatgaaatg gatacttact acccaatagt
      181 tcccgctaat caaacaatga aagaaaacat acagtctctt tttgatgata ttgttaaaag
      241 tagaaaaagt aataccctat tgtattttaa ctgttcagat aatatggtag tgccatcccc
      301 atatggagat attgtttata ggtttataaa agagctaata aacaatgcta taaaatatgg
      361 agatggaaaa gacattcgtt tatctttaac gattcaatct gatattatta tcattgagga
      421 gagcaatcaa gtagtggaaa aagtacactc tataagttat ggcagaggat tgaaatcatt
      481 tcaagaaaca ctagcagctt ttgatggaga tctagaacta caaatggata ctaaacaatt
      541 tactatcaga atattacttc ccatagattg gaaattgtgt tatgaagatt ttattaattg
      601 atgaccacag actatttgca aagagtatcc aactgttatt ccaacagtat gatgaagtag
      661 atgtcataga tacgattact tctcatttta acgatgtgac gattgatttg tctaagtacg
      721 atattacatt gcttgatatt aatttaacaa atatttctaa agaaaatgga ttggagatag
      781 caaaagaact catacagtct actcctcatt tgaaagttgt tatgttgaca ggatatgtta
      841 aatcaatcta tagagagagg gcaaaaaaag taggagcata cggttttgta gataaaaata
      901 tagaccctaa acaactcatt tctatcttaa aaaaagtgga ttctggaaaa aagtattttg
      961 aacaaatcga atctcaggat tatgttgaat ctttaactga ccaggaaata gctatcttaa
     1021 atttgagtaa gaaaggattc tctataaaag aaatagagga aacgttacaa attagtagga
     1081 gaacagtatt taatcatttg acccacatct actcaaagct tttggtaaat aataagcaag
     1141 aggctatcta caaagccgaa caattagggt attttatgga tttctgagtt gcagataatc
     1201 aaacgacata agttttactt gtgtcgttgc tagggatttc ctgttaaata cccagattta
     1261 aactcattgt ttttgagttc tttttgattg aaattgattg agataacgct tttataaaaa
     1321 gtagggcaat gcctgatatg aaaagctttt taaatttagt caaacaaaag ttgtttaaac
     1381 caggtctaaa aaaactcgta aagcttcaca actcccagaa cgttaatata tgcttatata
     1441 tcaacgattg gaactacttt atggttcgca ccatggtttt tgtggaagga tcaaaagttg
     1501 tcctgaaaat ttctcttaac cgtgtttaag ctttctaaac gtttgagaaa tcattgtaac
     1561 ttcaaataac tattttaaat aaaacaaaga aacggacaaa gttagatgag atgattctat
     1621 tttgatttat aggtgaagaa ggagaatctt gtttgataag tactcaataa aggttcacta
     1681 cccaatttta aataaaacgc cacagtagta atcatctact gtggtgtttt ttggtctttt
     1741 agtttctaaa agtatccaat tcgtcttgtg cttctttggt tgttccgact agttgtttca
     1801 tgagttgatc tagtttggca tttgttttgg caatttcttg atcaatgtca ctgagctgtt
     1861 tagctaattc tggcagtggt ttgacgggga cttcctcaaa ggtatcgaca tagcgtggga
     1921 tatttaagtt atagtcattt tcaatgattt catcaaatga ggctaaatat gaaaacttat
     1981 cagaattatc acgactctta taagcatcaa ggatcttttt gatatggcta tctgtcattg
     2041 tgttttgatt tttgccttta tcaaactctt ttgaagcatc gataaagaag acatctttgt
     2101 tggttctgtt cttctttaat atgataatag tcgtagggat gcttgtatta taaaagatat
     2161 ttgatgggag tccgataatg gtatcgatag ccccttgttc gagtagtttt tggcgaatct
     2221 tgccttctgc agcaccacgg aaaaggacac cgtgtggtaa gacaatcgcc atagttcctg
     2281 tattttttaa atgatagaaa ccatgaagta aaaaggcaaa gtcagctttt gattttggtg
     2341 ctaatacacc ataacttgaa aaccgtggat ctgttaagaa accagcagtc gctgaccatt
     2401 tcaaagaata aggtgggttc attaacactc catcaaagtt tgttggttca tctgttggcc
     2461 agtctgcatc caaggtatca gcgttactta agtgttggtt ttcgatggca acgccatgaa
     2521 gcatcatgtt catacgagcc aagttataag tagaagtatt gatttcttga ccatagtaag
     2581 agacggtatc ggattggtta ctatatttct tagcatttaa aaggagtgat ccagatccca
     2641 tagcagggtc ataaagggtc attccttttt gatcttccca acctaaaaag acaatctgag
     2701 tcatcaagtg agagacagct tgtggggtat agaactcacc tgcttttttt cctgactcac
     2761 tggcaaattc accaatcaag tattcataag catcacctaa agtatcccca tctactgcct
     2821 caaagtcaat ttcatttaat gttttcatga cattagaaat ggtttgattt tgtttttgag
     2881 gagtagagcc taatttttta gagtagaggt caatatcttc aaataagttt tcaaagtctt
     2941 caccactttg ttcaatatcg cgaaaacctt gagctaatga ttctaattgg aaagtattgt
     3001 gataaacatc ttggatgagt ttttcaaagg tcagtgtagg ttcgataaag taacctaaat
     3061 caccagtaac aacagaaatg aggtcatctt ttaggccttc atcttgatag gcattttcaa
     3121 agattttttg agcatctgta aaggtattaa agtgttcttc taaattatca caaacagcaa
     3181 agagtaattt atcagataaa tgtttgtaaa agatgagtcc aagaagatag tttttatagt
     3241 cattggcatc catttggcca cgtaattgat cggccgaatg ccatagtgct tgccgtagtg
     3301 aagttgtttt ctctgccatg tgcgtccttt cttatacgaa taaacgattg agtaatgttt
     3361 gtttgagtgc tttgagttct gttagttttt cttcagattg agcaatttgt tggtctaaag
     3421 tttggaagaa attaccaatg gcttcttgtt ctgagaggga agggatttga attttagcat
     3481 atttgatatc actagagcta atgctatcaa aagttgaacc tgtactaatt cttttccaat
     3541 aaccaatttc tttcaagtat tttaatattt gaaagataaa ttcattacct tttatagcag
     3601 caactccacg cccaataata acatgataat ttgtctttcc aacatcacca actggagccc
     3661 taacactaag aataatatca cctttgtcag cttgttttgt aatttgtgtt gtccagacac
     3721 gcggaaaaac atatccattt tttatatcgg catttccttg tactagaata taatcagaag
     3781 ggtttgtagt ataattttga cttgatggag attggcccat tgtaatttga acaatatcac
     3841 ctagttcctt ctcttcccac tcaccatcaa aaccttgtaa acggatttca gggacttttt
     3901 gtccttgagc tgggaacatc tttctgagga aggtttgctt ttgttcttta aggattgcta
     3961 gcttttgcct ctgtaactga attaactgat caaccgtttg gaagagttcg ccaatggctt
     4021 cttgttcagg gagggagggg agattgataa cttgatttcg aattatttca gaattcagat
     4081 tcacttggct tcctggttga ccatatttat tccaatatgg tctgaacata tctaaccact
     4141 gaaacataaa ttcacggttg aatttaggat ctaaaaacac aagaaatcca tcgtgtactc
     4201 cagttttaac ataattgata actggtttac ctactgtagc tgcaatactt aatagtaaat
     4261 gtggatcctt taatactcta gtcttttctt gaccaagctc agatattctt tgttgtaaat
     4321 aagttatacg accctcttgt tcagtaacat cagaaattct taaccaacct atatcacttt
     4381 tggcatcaaa ccattttgga tcttgtatcg gtctaggact ggcaccacga actatattag
     4441 aaatttctcc cagctttttc tcttcccact ccccttcaaa actgtcaaag cgatattgag
     4501 gccgtttaga ttttgtcatc tctttccttt cctagtgccc ttttaagggt tggatttgat
     4561 ctctaatgaa ttgaactaac tcccgttcaa attggctttt gtatttgagt ttattcatgg
     4621 ccgagtcacc ttgtttttct ttataggctt ggtagtctag ggattctttt aaggttgata
     4681 tgcccacttg tttggtagag ttagcactat gataattagt cgccacaaag gctaatttgt
     4741 caggatctgc cttccactgg tccgcaaagt gtttgatggc cctttggatc ttatcaccaa
     4801 tgaggttatc caactcataa gcaatgcttt tcccttcata ggctttgggt tctttttgga
     4861 tatcttgcca taactcagct agtgagtcag ccatagcagg gtttgatttt gccaaatctt
     4921 ggatgtattg atccatggga ttgtcattga gcctttcttg aagagcttct tgttcttgat
     4981 cgacaaaggc ttgaattaag gtcaagatat agtgatagtt gatatcatcc atctgaacac
     5041 tttctagctc atagtcgata ttgatctctg ggatggcttc gtcatcttct cttcgctttc
     5101 gtatttctgc aatgacattt tggtaagtgc ctttataagt atcaatcact tcatctgata
     5161 acccaacctc actcaatagt gtttcattaa agtcactata gacctgtaca gatgcataga
     5221 gcttatcaaa cgcttgaaag gctttggcgt attgtttgag aaaagctgtc tgtgcgctct
     5281 caatagttgg gaaagcgtct ggatcaggaa ctatattttt taatactgtt actttttcaa
     5341 agaatcttgc tttttcttct tcccaagaag gcgctaaaac ttcactttga ccaccatttg
     5401 agtataggct aagagccgta tcaacagctt ctttaaaacg aagtggtgtt tggaaagtca
     5461 caacctgacc gtaatgtttt ctactttcaa agatacggtt ggttcgtgag aaagcttgaa
     5521 taatgtgctg aggtttcata ggctggcgat cgatgaagat ggttgataaa caaggcgcat
     5581 caaagcctgt taagagacgg tcaaccacaa tcacgaggtc taattgttca tgacggtctt
     5641 tgaatttatc ttttttacgg gctaagcgat catttaaatc tctgttatag ccttgtaagt
     5701 tatcgatggt aaagttagtg ccaaagaggt gattatagtc ttctagattt ttggtcattt
     5761 tatcttgtcg gctgatagac gcattgtcat tttcagtgat agaataagta atagctacct
     5821 ttggaaagtc tggtagtttt tctttgacct tcttagaaat gactaaatcc gtttcaccag
     5881 ccttaacttt cttcatcaga tcataatagg cttgggcacg agcaatactc ttaacggtta
     5941 gtaaaccttc gaatgtctga ccaattccat tattaaaacc aagtttcttg cgtgattgat
     6001 taatgatact atctaagaca gctaacatat gttcttcatg atcataagct tcttccggaa
     6061 tactgtcttc aggcatatca ggaatggttg tcttatactc aacttgaaag cctagaaccg
     6121 ctttatcatg aatggcttct ttaacggtgt attgatggag acatttgccg tattgctgtt
     6181 ccgttgtttg ggctaaatca cctaattgag cacgcttatt ttccacaaag ataggagtgc
     6241 cggtaaagcc ataccagcga ctgttacgaa aagtattcgt gagataacgt tgacgttccg
     6301 gtgtgacagc acggtggcat tcgtccacaa caaagacaac atttaagtgt gcaagacgct
     6361 cttttagttt cttgaatttt ggagtgtcat aactttccat ctgactgatc atggcattga
     6421 gtttttgaat ggtggtggcc acaacacgac gatcactgga ttctaaattt ttgatgagtt
     6481 gtctcgtatc ttctgtctca tcgacatcaa agatatcatt ttgcgcatag gattgaaaag
     6541 cagaagcggt ctgattatct aaatcctttc ggtcaatgac aaagatggat ttttcaacgg
     6601 ccggtatttg aaggatattg cgagccactt tataggaagt taaggttttt ccagaacctg
     6661 ttgtgtgcca gatatagcca gacttgcggt gacgactcgc ttcagcgacg gcttcgattg
     6721 catgaatctg ataaggacga aggagaatta gtgctttttt atcatcatca atgacagagt
     6781 aagtcatgac catttggtga gcacgaggga tagataggac ttctttggca aaggcaaaga
     6841 gatctttttg tggtttgttg ttttgatcta cccattgggt caagaagtta gggtttaatt
     6901 tattttcttt agctgcagcg atataccttg tatctgtttt atttgagacc acaaacattt
     6961 gtaaggttga aaagatacct ctaaactggc cttctttatc atactttttg acttggttaa
     7021 aagcttcaat gcattgatga ttctgagatt ttaattcaat ttggatcata ggtaagccat
     7081 tgatgagaag tgtcacatca cctcgtctat cacgagaacc agagaaagca acttgattgg
     7141 caatctcata aacagaagtt ccaccagcca cattgtctgc tttaacgact tctaaacgaa
     7201 tcgttcctag ttttgcatct tcgcgttgca cttgtacttt agcaatgccg ttttcaccag
     7261 ctaaccattt agccgcttca tagtaattga caaagttaag ttgattctta atctgctctt
     7321 tttcactagc tgttaaaggc tcctcattca gatattgcgt gttattttgc gctaagatct
     7381 taaagaaatt atcccataaa gcatcttcag tttttaattc tttacgatat gtccattgac
     7441 tttcacctgt ttctaagaga tggatcaact ctttttcaag ttcaagttcc gttttagttt
     7501 gatttcccat ttttaatccc cattcgacat gatatagtaa tattatatca ttggcggatc
     7561 ctttttagaa tggcaaagct attgaaacct tccaaacagt ctttttttga ttagttgaat
     7621 gcttaagatc ctagcaacta aacaaagcta tgactatgta aatgcaatcg agaaagttct
     7681 tgtatttttg agtttgcttg acaataattt aaggcgaaga aagtaataag acaacactag
     7741 taaaaaggtc gagttctcaa aatagataaa aaacttaaga cagatctagc ttgactatta
     7801 atagggtttt aaaggacgat aatctgctac aatatacaga aaaggaattt attgaagata
     7861 tgaaaatttt ggtagccata gattctttta agggatcggt aacgtctcca gaacttaaca
     7921 ctagtgtagc tcaagccctt ctttctgtcg ataagcagtt agttattgaa acaagagcta
     7981 tcgctgatgg aggagaagga agtttagcag ccctctcaca aaccgtggcg gggaggtggc
     8041 atcaagtaaa aaccattgat ctattaagac gcccgattaa agtcgcttat tatcgtcacg
     8101 caaagcaagc ttttattgaa tctgcgagta ttattggtat tgataagatc acccccaatt
     8161 cagtaaccta tgcacaagcc acttcctatg gtttgggttt ggcagttaaa gatgccattc
     8221 aaaaaggagc tactcaaatc gaaatcatgc taggaggaac aggcacttct gatggtggca
     8281 aagggttttt ggaaagttta aactatgatt tcatgacagg aagatcttat cttgatactt
     8341 tagcatcacc tgttacgcta ttagggctga ctgatgtgac caatccatat catggccctc
     8401 aaggatttgc tgcggtcttt ggccctcaaa aaggtgggag tcttagtcaa attgaagaaa
     8461 ctgatcaaat tgcaagtaac tttgctaaaa aagtttttta ccaaaaaacc attgatttac
     8521 agacaatacc aggaagtgga gcagctggag gattaggagg tgccattgtc ctattaggag
     8581 gcaccttaac tagtggtttt agcaggattg cagagctact aaatctggat aattcccttc
     8641 agtcctgtga tttagttatt actggagaag gatgcctgga tacacaatca caatctggca
     8701 aggtacctgt tgcgattgca agaatggcta aaaaatatca agttccaacg attgctctat
     8761 gtggttctgt aaagattgag acaggactag cagcagaaga ctttttggct gttttttcaa
     8821 tacaacagca gccaatttcc ttagaagcag cgatagataa aacaacaaca ctttccaata
     8881 tcaaaatatt agtagctaac cttatgctat tgatagccca gtttaataag taaactcatc
     8941 tattttcgat tgtgtagcat tcatttggcg gttaaaagta acctatgaag aaggagacgt
     9001 acgagctaac tcattagcat agtatgaaaa acagaaacat tttgtaaaaa aaagagttga
     9061 caatgacagt aaagatatcg tatactaata aagctgtcag agaggttgct gtaacacact
     9121 tattgaaaaa agatgaaaaa gtagttgaca ggctatgaga aacctgatag aataaagaag
     9181 ttgtctctta ggagacgt
//
LOCUS       DATWEK010000052         8798 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.052, whole genome shotgun sequence.
ACCESSION   DATWEK010000052 DATWEK010000000
VERSION     DATWEK010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8798
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.052"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(68..373)
                     /locus_tag="VCR92_001649"
     CDS             complement(68..373)
                     /locus_tag="VCR92_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEP4268700.1"
                     /translation="MTHNHENDHQHEVITLVDEQGNETLFEILLTIDGREEFGKNYVL
                     LVPAGSEEDESGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEN"
     gene            complement(385..804)
                     /gene="ruvX"
                     /locus_tag="VCR92_001650"
     CDS             complement(385..804)
                     /gene="ruvX"
                     /locus_tag="VCR92_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEP4268701.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKIDEEKAEFGFTR
                     LEELVKQYQVEQFVIGLPKNMNNTNGPRVDASITYGNHIEHLFGLPVHYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLNRNF"
     gene            complement(801..1070)
                     /locus_tag="VCR92_001651"
     CDS             complement(801..1070)
                     /locus_tag="VCR92_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEP4268702.1"
                     /translation="MGFTDETVRFKLDDGDKRQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDVK"
     gene            complement(1184..1582)
                     /gene="spx"
                     /locus_tag="VCR92_001652"
     CDS             complement(1184..1582)
                     /gene="spx"
                     /locus_tag="VCR92_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEP4268703.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLAYKEQNLGKEPLTKEEILA
                     ILSKTENGVESIVSSKNRYAKALDCDIEELSVSEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENTEARLRAAL"
     gene            complement(1873..3009)
                     /gene="recA"
                     /locus_tag="VCR92_001653"
     CDS             complement(1873..3009)
                     /gene="recA"
                     /locus_tag="VCR92_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEP4268704.1"
                     /translation="MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFD
                     EIDRKVRVKFGLLEESEEESAMVVASEEIDDLALDLDNGIEIED"
     gene            complement(3098..4369)
                     /locus_tag="VCR92_001654"
     CDS             complement(3098..4369)
                     /locus_tag="VCR92_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEP4268705.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVITTASQRSDLVILCGGLGPTKDDLTKQTLAKYLRKDLVYDEQACQKLDDF
                     FAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
                     VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTL
                     RLSTKTENQALADKKLGQLEAQLLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKY
                     DKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKMLGLPLEELKSHGVV
                     SAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLI
                     SGRSRLDVRYIATLHAFNMVRKTLLKLENLL"
     gene            complement(4438..4998)
                     /locus_tag="VCR92_001655"
     CDS             complement(4438..4998)
                     /locus_tag="VCR92_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEP4268706.1"
                     /translation="MKRCSWVPKDNQLYCDYHDLEWGQPLHDDRDFFELLCLESYQSG
                     LSWLTVLKKRQAFRTVFHHYDIASVAAFTSEEMADALENPSIIRHKLKLAATVNNAIA
                     VQKIQEEFGSFSTYLWNFVGGKPINNLVNQENLVPAQTELSIRLAKDLKKRGFKFLGP
                     TTVYSFMQASGLVNDHEEACVFNRIF"
     gene            complement(5008..5604)
                     /gene="ruvA"
                     /locus_tag="VCR92_001656"
     CDS             complement(5008..5604)
                     /gene="ruvA"
                     /locus_tag="VCR92_001656"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEP4268707.1"
                     /translation="MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLV
                     TIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGIGPTTALAIVAVDDNEGLVNAID
                     NSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
                     LALGYKAAELKKIRAFFEGTSETAEQYIKSALKLLMKG"
     gene            complement(5606..6826)
                     /locus_tag="VCR92_001657"
     CDS             complement(5606..6826)
                     /locus_tag="VCR92_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP4268708.1"
                     /translation="MQEFLNLPKQIQLRQLVRFVTITLGSSIFPFMAMYYTTYFGTFW
                     TGLLMMITSLMGFVGTLYGGHLSDALGRKKVIMIGSVGTTLGWFLTILANLPNAAIPW
                     LTFVGILLVEIASNFYGPAYEAMLIDLTDESNRRFVYTINYWFINIAVMFGAGLSGLF
                     YDHHFLALLVALLLVNVLCFGVAYYYFDETRPETHAFDHGKGLLASFQNYRQVFHDRA
                     FVLFTLGAIFSGSIWMQMDNYVPVHLKLYFQPTAVLGFQVTSSKMLSLMVLTNTLLIV
                     LFMTVVNKLTEKWKLLPQLVVGSLLFTLGMLLAFTFTQFYAIWLSVVLLTFGEMINVP
                     ASQVLRADMMDHSQIGSYTGFVSMAQPLGAILASLLVSVSHFTGPLGVQCLFVVIALL
                     GIYFTVVSAKMKKV"
     gene            complement(6837..>8798)
                     /gene="mutL"
                     /locus_tag="VCR92_001658"
     CDS             complement(6837..>8798)
                     /gene="mutL"
                     /locus_tag="VCR92_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEP4268709.1"
                     /translation="PEVLANQIAAGEVVERPASVVKELVENAIDAKSSQITVEIEESG
                     LKMIQVTDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPSVASISKI
                     TIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKYMKSLQAE
                     LAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTTKKMLAIS
                     NADLDFEVSGYVSLPELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKLMVGRFPI
                     VVIDIQIDPYLADVNVHPTKQEVRISKERELMALISTAISESLKEQDLIPDALENLAK
                     SSTRHFSKPEQTQLPLQFRGLYYDPQKNDFFVKESAVSEKIPETDFYFGAVDNSVKVE
                     KAELLPHSEEVIGPSSVKHASRPQNTFIETDHPNLDLKNRQKLSQMLTRLENEEQSVF
                     PELDYFGQMHGTYLFAQGKDGLFIIDQHAAQERVKYEYYRDKIGEVDSSLQQLLVPYL
                     FEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEEEIASGVYEMCDML
                     LLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPV
                     LINFSKADMEKMFRRIQENHTSLRELGKY"
BASE COUNT         2697 a         1929 c         1464 g         2708 t
ORIGIN      
        1 tttattcgaa aataacatta aaaaaatagc cctcacggct actttttaac atagtgtcac
       61 taacaattta gttctcatct agaaaactat taaatacctc ttcaatcata tcccattcag
      121 catctgaatc ctcaggaatc ggttgtaaat ccccttcagt accatcttca ttttcagtaa
      181 atgaataggc ttggatttca atttcaccag actcatcttc ttcagatccc gctggaacca
      241 agagaacata atttttacca aactcttcac gaccgtcaat tgttaataaa atttcaaaca
      301 aggtttcatt tccttgttca tccacaagtg tgataacttc gtgttggtgg tcattttcat
      361 gattatgtgt cattttttat ctccttaaaa attccgattt aaatagttct gtaaaatgag
      421 ttgtgcagct aatttatcaa tgactttttt tcgcttacca cgactaatgt cagcttgctc
      481 aataagcata cgctctgcct caacagtcgt caatcgttca tcttgataat ggactggaag
      541 tccaaagagg tgctctatgt ggtttccata agttatactt gcatcaacac gtggaccatt
      601 ggtgttattc atattttttg gcaatccaat aacaaactgt tcaacttggt actgcttaac
      661 aagctcttct aaacgtgtaa agccaaattc tgctttttcc tcatcaatct tgataatttc
      721 aagtccttgg gctgtaaagc caagaggatc actaatagct acaccaaccg ttttcgagcc
      781 aacatcaagt cccattattc tcatttaaca tcaattccat ttccttgtaa atagtagcga
      841 acaagttctt ctacaatttc atcacgttca tatttacgaa tctgatttcg agcatcatta
      901 taacgaggaa cataagctgg gtccccactc aagacataac caacaatttg attaattgga
      961 ttataaccct tttcatcaag tgaatgatag actgctgtta atgtttcact aatttgtcgt
     1021 ttgtcgccat catccaactt aaagcggact gtttcatctg taaatcccat acttacacct
     1081 tctttctaaa attaagtgct atgctttatt atagcttatt tctattaaat aaacaagaat
     1141 ttcaagcgaa gaaggtattt aaaaaaaagc tctacaagag cttttagagt gcagcacgta
     1201 atcgtgcttc agtattttca atattacgaa tagagcgagg taaaaaagca cgaatatcgt
     1261 cttctttgta gcctacttgc agacgtttat catcaatcaa aatgggactt ttaaggatgc
     1321 gcgggttatc ttgaatcaaa tcaataacct cactaacact tagttcttca atatcgcaat
     1381 cgagagcttt ggcataacga tttttagatg aaacaatgct ctccactcca ttttcggttt
     1441 ttgataaaat tgctaaaatt tcttctttag ttagcggttc ttttcctaag ttctgttctt
     1501 tataagcaag cttatgggca tttagccaag ttttggcttt cttgcagctc gtacaacttg
     1561 aaatcgtgta aattttaatc atgttgctga ctcactttct atttcgtgat agctttattg
     1621 tagcacagtt tcttatctat aaatataggt ctttggacct atttttttaa ttttaaagat
     1681 attatcttgg taaaataagg tttttcacct gtattccctt gaattattag ttattttaat
     1741 tttatatcag ttaacctaag ttctgctctc tcacatcttt ttaaatgatg gtttctattc
     1801 acccacacac ctatgaatag tagtcctact aacctttaaa aatacatttt aaaaagccct
     1861 gaagggctct ttttaatctt caatttcaat accattatct aaatctaaag caagatcatc
     1921 gatttcttct gatgctacta ccatagcaga ttcttcttcg ctttcttcaa gcaaaccaaa
     1981 tttaacacgt actttacggt cgatttcatc aaacaattct ggatgatcgg ccaaataacg
     2041 cttagcattt tcagaacctt ggccaatctt ctcaccatta taagagaacc aagcacctgc
     2101 tttttggata atgtccaaat cagaagcaat tttcacaagc tcccctgtac gagaaatacc
     2161 ttccccatac atgatttcaa cttctgctac cttaaatggc ggagcgacct tgtttttaac
     2221 aaccttgatt ttggtctcct taccaatgct gctatctttt tggtcaccag ttcctttaat
     2281 ttgagttgtt ccacgcacat ccaaccgaac agaagcatag aatttcaaag ctcgaccacc
     2341 tggtgttgtt tcaggatttc caaacatgac accaactttt tcacgcaatt ggttaataaa
     2401 gatagcgata gtttttgttt tattaataga agctgataat ttacgcatag cctgactcat
     2461 catacgtgct tgcaatccga catggctatc gccaatatca ccatcaattt cagcacgtgg
     2521 cactaaagct gctactgaat cgacaacaac cagatcaacc gcaccagaat caatcaattt
     2581 acctgcaatt tcaagtcctt gttctccaga atctggttga gacaagagga gttcatcaat
     2641 attaacccca agcgcagcag cataagctgg atcaagcgca tgctcggcat cgataaaggc
     2701 tgcgattcca ccttcttttt gagcttgtgc tacagcatgt aaagccacag tcgttttacc
     2761 ggaagactct ggaccataga tttcgatgat acgtccttta ggataaccac cagctccaag
     2821 cgcaatatca agagctagac ttcctgaact cataacctga actttttgct ctgcacgttc
     2881 tcctaatcgc atcactgcgc ccttaccaaa atctttttca atatttttca aagcatcatc
     2941 aagggctttg cgacgttcgt caccaaactt cttagtgatt tcttcattct tttttaattt
     3001 ttttgccaat actttctcct cttttttaac aaaccatcgt cagcaggatt aatctacata
     3061 atcgtaaacc atatcctact atagctacta aataacatta tagcaaattc tcaagtttta
     3121 ataaagtttt acggaccata ttaaaggcat gtaaagtagc gatatagcgc acatccaaac
     3181 gacttcgccc gctaatcaaa acctttattg attctacctt attttgagtg gcaaggccaa
     3241 tgaaaactgt acctgcaggc tgttcctcca acatatctgg tccggcaaca cctgttaaac
     3301 ttaccccaat atcagcacca gtcaataacc ttgcttgctc cgccatcccc tcggctgtat
     3361 aagcactaac aacgccatgc gatttcaact cctctaaagg aaggcctagc attttcgctt
     3421 tttcttccat gctataagtc acaaagcctc cattgaatac ttgagaagct cctggaaaac
     3481 tcgccaaagt tgactgaaat aatcccgcgg ttagactttc tgctgctgta attgtcttat
     3541 catattttac taagagctca aatgtctcac gcgctaagga attatcctcc ccatagccat
     3601 aaaagacatc agctaagggt tgaccttcaa gagtttttcg ggatagtagc tgcgcttcta
     3661 gctgacctaa ctttttatct gccagagctt ggttttcagt ttttgttgat aagcgaagag
     3721 tcacttcgcc agtcttagca tacggagcaa tggttggatc agtttgattc tcaataaaat
     3781 ctgacaagac tgttaccaac tgactttccc caataccaaa aaagcgtagt acctttgaat
     3841 acaatgtact gtattgtttt gacagaagtg gtaccaattc ttcatttacc atcggcttca
     3901 attcacttgg aggacccggt aagacaacat aactaatacc atcgactgtg atgaacccac
     3961 caaccgcaag accagtttta tttggcaaag ggattgaccc ttcaatcact tgtgcctgtc
     4021 gctcattatt tggtgtccgt gatgaaggct tgcgcttagc aaaaaagtca tctagtttct
     4081 gacaagcttg ctcatcataa accaagtctt tcctaaggta ctttgctaaa gtttgtttgg
     4141 ttaaatcatc tttcgttgga ccaaggccac cacataaaat taccaagtca ctacgctgac
     4201 tagcagttgt aatcactgaa agtaaacgct cctcgttgtc cccaacagcc gtttgaaaat
     4261 agacatcaat acctagctct gccatttttt ccgacagaaa ttgagcattg gtattcacaa
     4321 tttgaccagt caaaatttcg gtacctactg caatcagttc agctttcatt tccccaccta
     4381 cttatctatt cgtaatctga tctcatttta tcaaaaaatc ttccaattca cgaagaatta
     4441 gaagattcta ttgaaaacac aagcctcttc atggtcattt accagacccg atgcttgcat
     4501 aaaagaataa accgttgtag gccctaaaaa tttaaatcct cttttcttta aatccttagc
     4561 taagcgaata gataattctg tttgagcagg aacaagattc tcttgattga caaggttgtt
     4621 aattggcttt cccccaacaa aattccagag ataagttgaa aaactaccaa actcttcttg
     4681 aattttctgt actgcgatag cattgttgac agttgctgct agctttagct tgtggcgaat
     4741 gatggatgga ttctctaaag cgtcagccat ttcctccgag gtaaaggctg caaccgatgc
     4801 aatgtcgtaa tgatgaaaaa cagttctgaa agcttggcgt tttttcaaaa cagtcagcca
     4861 ggataagcct gactggtaac tttcaaggca gagtaattca aaaaaatctc tatcatcatg
     4921 taggggttga ccccattcta aatcgtggta atcacagtaa agctggttat ccttaggaac
     4981 ccatgaacaa cgtttcatgt gaaacaccta gcctttcatt aatagtttaa gggctgattt
     5041 gatgtattgt tcggccgttt cagaggttcc ttcaaagaag gcacgaattt tcttcaattc
     5101 cgctgcctta taaccgaggg caaggagggc ttcaatcgct tcgtccagtt gagtattgcc
     5161 tgctttattg ctgcgcgctt tggtattacc agtctcttgt ggagcctcca caaatttgcc
     5221 agctaagtca agaaccattt gctgcgctgt ttttttacca attttaggaa atttcattag
     5281 gtacttaatg tcactgttat caatggcatt cacaagtccc tcattatcat caactgccac
     5341 aatagcaaga gctgttgtgg ggccaatgcc agatacagaa attaatttca gaaaaacatc
     5401 tttttcgtct tccgtatgaa acccaaacaa caagtgagca tcctcacgaa tcacttgatg
     5461 caggtaaata gttaccagtt ggttgacact atctgtaaag ctataaggat tggctacatt
     5521 gataatatag cctagtccat ttgtttcaac gacaatgtat tttgccgtaa ttttggtcaa
     5581 ttgaccttta atataatcgt acatactaca cctttttcat ttttgcagaa acaaccgtaa
     5641 aataaatccc tagcaaagca atgactacaa ataagcattg cacacctaaa ggacctgtaa
     5701 aatggctgac agatactagt agactagcca aaatagcacc taggggttgt gccattgaca
     5761 caaaacctgt ataagatcct atttgggaat gatccatcat atcagcacgt aggacttgac
     5821 tagcaggaac atttatcatt tccccaaaag ttaacaaaac aactgatagc caaatagcat
     5881 agaactgcgt aaaggtaaat gccaagagca tccctagagt aaatagtaaa gaaccaacca
     5941 caagctgagg taatagtttc catttttccg ttaatttatt tactactgtc atgaaaagga
     6001 caatcagcaa tgtattagtt aaaaccatta atgataacat tttagaacta gttacttgga
     6061 aacctaacac agccgttggc tgaaaataca gtttcaaatg gactggcaca tagttatcca
     6121 tctgcatcca aatactacca gaaaagatgg cacctaaggt aaacaagaca aaggcacgat
     6181 catgaaacac ctgacggtag ttctgaaaac tcgccagtaa tcctttacca tggtcaaaag
     6241 cgtgtgtttc tggtctagtc tcatcaaaat agtagtaagc aacgccaaaa caaagtacat
     6301 taacgagtaa taaggctact aacaaggcta aaaaatgatg gtcataaaaa agcccagata
     6361 gccctgcacc aaacatgacg gcaatattga taaaccaata attgatggtg taaacaaatc
     6421 gacgattact ctcatcagtc aaatcaatta acatagcttc ataggcagga ccataaaaat
     6481 tagaagcaat ctctaccaat aaaataccca caaaggttaa ccaaggaata gctgcattag
     6541 gcaaattagc taaaatagtc agaaaccagc ctagtgttgt tcctactgac ccaatcataa
     6601 tgactttttt gcgaccaaga gcatctgaca gatgcccacc gtataaagtt ccaacaaatc
     6661 ccatcaaact ggtaatcatc attaagaggc ctgtccaaaa cgtaccaaag taagtcgtat
     6721 aatacatggc cataaaggga aaaatactac tgcctaaggt aatggtcaca aagcgtacca
     6781 gttgcctcag ctgaatctgc ttaggaagat ttaaaaactc ttgcatctca tcctctctaa
     6841 tattttccta gctctcgcag gctagtgtga ttttcttgga tacgacggaa cattttttcc
     6901 atatctgcct tactaaaatt aatcaatacg ggtctaccat gagggcagtt ataaggattt
     6961 tgacattggg ccaattgcag tagcagattt cttgctgaat aatcatccaa gctatgattt
     7021 gccttgatag atcgtttaca actcatcata atagctaact ctgctcggta agttttaata
     7081 gatacctcat tggttagaag taacatgtca cacatttcat agacaccaga tgcaatctct
     7141 tcttctttca tccagatagg atgctccctc aaaatgaaag tattgtgccc ataaacttct
     7201 aagaagatac caacttcatt taagagtgcc attttctcct gtaagttaat gaaatcagaa
     7261 ccagaaaact caaacaaata gggcaccaac aattgctgta aactactgtc aacctcacct
     7321 atcttatcac gataatattc gtatttaacc cgctcttgag cagcatgctg atcgataata
     7381 aataagccat ctttaccttg agcaaagaga taagttccgt gcatctgacc aaaataatcc
     7441 aattcgggaa acactgattg ctcttcattt tccaaacggg ttagcatttg agataacttt
     7501 tgtctgtttt ttaagtcaag attaggatga tcagtctcga taaaggtatt ctggggacga
     7561 cttgcgtgtt taaccgaaga aggtcctata acttcttctg agtggggtaa cagctctgct
     7621 ttttcaacct ttacactgtt gtcaacagcg ccgaaataaa aatcagtttc aggtattttt
     7681 tccgagacag ccgactcttt gacaaaaaag tcattctttt gaggatcata ataaagtccc
     7741 ctaaactgta aaggaagttg tgtttgctct ggtttagaga aatgtcgtgt gcttgatttg
     7801 gctaagtttt ccagagcatc tggaatcaaa tcttgttcct taagactttc agaaatcgcc
     7861 gtactaatta aagccatcaa ctcacgctct tttgaaatac gaacctcttg ttttgtggga
     7921 tgaacattga catcggccaa atagggatca atctgaatat caatcacaac aattgggaaa
     7981 cgtccaacca tgagcttaga accgtaacca tcaagaattg ctcgattaag caagaaattc
     8041 ttgatgtaac gcccattaac caaaatcgtc atgtaattac ggttggcgcg tgtcaactct
     8101 ggcaagctaa catagccgga aacttcaaaa tccaaatcag cattagagat agccagcatt
     8161 tttttggtag tattcaaacc atagatccct gcaattgctt ggcgtaaatc gccagttcct
     8221 gatgtctgag ttaattggcg accatcacta atcagtgtga aagcaacttc tggatgtgcc
     8281 aaactcaacc ggttgaccac atctacaatg tgagctaatt ctgcctgtaa acttttcata
     8341 tatttgagac gagcaggcgt gttgtaaaaa aggttttcaa ccttaatttt ggttccagta
     8401 ggagttgaga tcgcttcaag tgtctcaatt tccccaccag tagctataag aagagaaccg
     8461 tgagtgactt cttttgttgc tgtttttatc gtgattttac tgatagaggc aacagacggt
     8521 aaagcctctc cacggaagcc aagtgttcta attctaaaca aatcactctg actcttaatt
     8581 ttactagtag cgtggcgacg cagacttaaa ggtaaatctt catgagacat tccctcaccg
     8641 ttgtctgtaa cctgtatcat cttaaggcca gactcttcaa tttcaacggt aatctggcta
     8701 cttttagcat caatagcatt ctcaaccaat tccttgacaa cactcgctgg cctttctaca
     8761 acttcaccag ctgcaatttg gttggcgaga acttccgg
//
LOCUS       DATWEK010000053         8479 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.053, whole genome shotgun sequence.
ACCESSION   DATWEK010000053 DATWEK010000000
VERSION     DATWEK010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8479
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.053"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..2536)
                     /locus_tag="VCR92_001659"
     CDS             complement(<1..2536)
                     /locus_tag="VCR92_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEP4268710.1"
                     /translation="MKNNNKWIIAGLASFLFPLSIIFIILLSMGIYYNSDKTILASDA
                     FHQYVIFAQNFRNIMHGSDSFFYTFTSGLGINFYALMCYYLGSFFSPLLFFFNLTSMP
                     DAIYLFTLIKFGLIGLAACYSFHRLYPKINAFLMISISVFYSLMSFLTSQMELNSWLD
                     VFILLPLVVLGLNKLITENKTRTYYLSISLLFIQNYYFGYMIALFCILYALVCLLSLN
                     DFNKMFIAFVRFTAVSICAALTSALVILPTYLDLSTYGENLSPVKQLVTNNAWFLDIP
                     AKLSIGVYDTTKFNALPMIYVGLFPLMLSVIYFTLESIPLKIKLANACLLTFIIISFY
                     LQPLDLFWQGMHSPNMFLHRYAWSFSIVILLLACETLSRLKEVTQIKAGFAFIFLIIL
                     TSLPYSFSQQYNFLPLTLFLLSVFLLLGYTISLFSFRNSQIPPTFISAFILIFSLLES
                     GLNTYYQLQGINKEWGFPSRQIYNSQLKDINNLVNSVSKNSQPFFRMERLLPQTGNDS
                     MKFNYYGISQFSSVRNRLSSSLLDRLGFQSKGTNLNLRYQNNTIIMDSLLGIKYNLSE
                     GPLNKFGFTKLKTSGNTTLYQNHYSSPLAILTRNVYKDVNLNVNTLDNQTKLLNQLSG
                     KSLTYFNLQPAQLISGANQFNGQISAQASDYQNSVTLNYQINIPKHSQLYVSIPNIIF
                     SNPDAKEVRIQTDNHNFIYTTDNAYSFFDLGYFADAKVATFSFVFPKNKQISFKEPHF
                     YSLSIESYLEAMNSIKQKNVHTYAKSNTVITDYNSKTKGSLIFTLPYDKGWSAQKDGK
                     NLPVKKAQGGFLSVTIPKGKGRVILTFIPNGFKLGLSLSCVGIIAYM"
     gene            complement(2619..4238)
                     /locus_tag="VCR92_001660"
     CDS             complement(2619..4238)
                     /locus_tag="VCR92_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEP4268711.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPSTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYNIMKEKDAI
                     YMKADFSEEDGVRAAELEGIFAELGGWEAESEASQLLQNLNIPEDLHYQNMSELANGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREMGNDFLTVENLSVTIDGEKI
                     IDNISFILRPGDKAAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSK
                     DFATEESILEWLRQFASKGEDDDTFLRGFLGRMLFSGDEVKKSVIVLSGGEKVRVMLS
                     KLMLLKSNVLILDDPTNHLDLESISSLNDGIKDFKESVIFASHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLDNPEVQARVAELWK"
     gene            complement(4317..5189)
                     /locus_tag="VCR92_001661"
     CDS             complement(4317..5189)
                     /locus_tag="VCR92_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEP4268712.1"
                     /translation="MKKRGIDLLLVTIGSFITAIGFNTMFVDNHIASGGMVGIAVVIK
                     ALFGISPSLFLMASNIPLLLMCYFFLGKQNFIKTLYGSWIYPIAIRSTNSLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLFVIGYVISVMENGFDSSKNVMIISKDYQAIREYITTVMDRGV
                     TKLPIRGGYTTSDKIMLMAIVSSHELPTLQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KQYKREDKDVLLPM"
     misc_binding    5312..5553
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5608..6630
                     /gene="trpS"
                     /locus_tag="VCR92_001662"
     CDS             5608..6630
                     /gene="trpS"
                     /locus_tag="VCR92_001662"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEP4268713.1"
                     /translation="MTKPIILTGDRPTGKLHLGHYVGSLKNRVFLQNENKYKMFVFLA
                     DQQALTDHAKESELIQESIGNVALDYLSVGLDPKQSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPSGFLVYPVSQAADITAFKANLVPVGNDQKPMIE
                     QTREIVRSFNHTYHTDCLVEPEGIYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRKKVMSMYTDPNHIKIEDPGQIEGNMVFHYLDIFARKEDQADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRERRLEYAKDMGEVFRMLQEGSQKARTVAAKTLSEVKSA
                     MGINYF"
     gene            6938..8419
                     /gene="guaB"
                     /locus_tag="VCR92_001663"
     CDS             6938..8419
                     /gene="guaB"
                     /locus_tag="VCR92_001663"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEP4268714.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTL
                     NIPIITAAMDTVTGSKMAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNR
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGDIQELHENAQFVEMSGAGLIESHPHDVQITNEAPNYSVH"
BASE COUNT         2841 a         1378 c         1619 g         2641 t
ORIGIN      
        1 gcatataagc gataattcct acgcaagata gagataaccc taatttaaaa ccattaggaa
       61 taaaggtaag gataacacgt ccctttcctt taggaatagt aactgataga aatcctcctt
      121 gtgctttttt gactggaaga tttttcccat ctttttgtgc tgaccaacct ttatcgtaag
      181 gaagtgtaaa aataagagaa cctttcgttt ttgaattata atcagtgatt accgtattac
      241 ttttagcgta agtatgaaca tttttttgtt taatactatt cattgcttca aggtaagatt
      301 caatagacaa actataaaaa tgaggttcct taaaactaat ttgtttattt tttggaaaaa
      361 caaacgaaaa tgtagcaact ttggcatcgg cgaaatatcc taaatcaaaa aaagagtaag
      421 cgttatctgt agtatatatg aaattatgat tatctgtctg aatacgcacc tctttagcat
      481 caggatttga aaatataata ttgggtatgc taacatagag ttgactatgt ttagggatgt
      541 taatttgata attaagggta acggagtttt gataatcaga agcttgtgca gatatttgtc
      601 cgttaaattg attagcacca gaaataagtt gagctggctg taagttaaaa taggttaaag
      661 atttcccact tagttggtta agtaatttgg tttggttatc aagggtattg acatttagat
      721 tgacatcttt gtaaacatta cgtgttaata tagctaaagg gctactatag tgattttgat
      781 aaagagtagt attcccgcta gtttttagtt ttgtaaatcc aaatttattt agaggtcctt
      841 cgctaagatt atattttata ccaagtagac tgtccataat aatagtattg ttttggtatc
      901 taaggtttaa attcgtgcct ttagactgaa atcccaatcg atccaataaa gaactagata
      961 gtctatttct tacagaggaa aattgtgaaa tgccgtaata attaaatttc atgctatcgt
     1021 tccctgtttg gggaagtagt ctttccattc taaaaaaagg ttgactattt tttgacacag
     1081 agttgacaag gttgttaata tcctttaatt gactattata tatctgtcgt gatgggaatc
     1141 cccactcctt attaattcct tgaagctggt agtaggtgtt taaccctgat tcaagaaggc
     1201 taaagataag tatgaaagca gaaataaaag taggtgggat ttgagaattt ctaaacgaaa
     1261 atagtgaaat agtataacct aataataaaa aaacactaag taaaaaaaga gttaaaggta
     1321 gaaaattata ttgttgagaa aagctataag gaagagatgt cagtataatg aggaaaataa
     1381 aagcaaaacc tgcttttatt tgagtcactt cttttagtcg agagagagtc tcacatgcga
     1441 gtaataggat aactatggaa aaagaccaag cgtagcgatg caaaaacata tttggtgagt
     1501 gcatcccctg ccaaaaaaga tcaagtggct gtaggtaaaa acttattata ataaaagtta
     1561 acaagcaggc attggctaat tttattttta aagggatact ttctaaagta aaataaataa
     1621 cactaagcat taggggaaat aatcctacgt aaatcatagg cagagcatta aacttggtag
     1681 tatcgtacac tcctattgag agcttagcag gtatatccaa aaaccaagca ttgttcgtaa
     1741 ctaactgttt taccggggat agattctctc cataagttga caaatctaga taggtaggaa
     1801 gtattaccag agcacttgtt aaagcagcac atattgacac agctgtaaac ctaacaaaag
     1861 cgataaacat tttgttaaaa tcattgagac ttaaaagaca aactaaggcg taaagaatac
     1921 aaaaaagagc aatcatgtag ccaaagtagt aattttgaat gaataataat gatatcgaaa
     1981 gataataagt tctggtttta ttttctgtga taagtttatt taatccaagt acaacaagtg
     2041 gaagaagaat gaaaacatct aaccaagaat ttagttccat ttgacttgtc aagaagctca
     2101 ttaagctata aaaaactgag atggaaatca tcaagaaagc attgattttt ggatataatc
     2161 tatgaaaaga atagcatgca gctaatccta ttaacccaaa ttttatcaag gtaaacaaat
     2221 agatagcatc tggcatagag gttaaattaa aaaagaaaag taatggagaa aagaaactgc
     2281 caagataata acacattaaa gcataaaaat ttatccctag tccgcttgta aaggtataaa
     2341 aaaaactatc agaaccgtgc atgatgttac gaaagttctg cgcaaaaata acatactgat
     2401 gaaaagcatc actagctaga attgttttat cactattata ataaatgccc atcgatagaa
     2461 ggatgataaa tataatacta agagggaaca aaaaactagc aagtccagca attatccatt
     2521 tattattatt tttcataaat tatatggtct ttcgtttaca aattttaaaa aagaggctag
     2581 gaagagatct tcttagccac ctcatttatc ataaggtttt atttccaaag ttcagcaact
     2641 cgggcttgga cttctggatt gtcaaggaat tcgtcataag tttcatctat acggtcgata
     2701 acaccatttt ttgaaataac aacgatgtgg ttagcaatcg tttgaataaa ttcatggtca
     2761 tgactggcaa agataacaga ttctttgaag tctttgatcc catcattaag acttgaaata
     2821 gattccaaat ccaagtgatt tgttggatca tcaagaataa gaacgtttga tttcaatagc
     2881 atcaacttag aaagcatgac acgcactttt tcgccaccgg aaagaacgat aacagatttt
     2941 ttaacttcgt ctccagagaa aagcatccgt cctaggaaac cacgtaaaaa agtatcgtca
     3001 tcttcacctt ttgaggcaaa ttgacgtaac cattcaagaa tagattcttc cgtggcaaaa
     3061 tcttttgaat tgtctttagg caagtaagaa cgacttgttg tcactcccca tttaatggtt
     3121 ccttcgtagt caatatcatc tgctaaagca cgcataagag cggttgtttg aatatcattt
     3181 tgaccaataa tagcagcttt gtcacctgga cgtaaaatga aactgatatt atcaatgatt
     3241 ttctccccat cgatcgttac agaaagattt tcaacagtga ggaagtcatt ccccatttca
     3301 cgctctgctt taaaattaat aaatgggtat ttacggcttg agggaacaat ttcttctaat
     3361 tcaatcttat caagcatttt tttacgagag gttgcttgtt ttgatttaga tgcgtttgct
     3421 gagaaacggg caacgaattc ttgtaattct ttgatttttt cttcggcttt agcattgcgg
     3481 tcagcttgta aacgagcggc tagctcagaa gattgtttcc agaaatcgta gttacccaca
     3541 aagagtttga ttttaccaaa gtcaaggtcg gccatgtgag tacatacttt attcaagaag
     3601 tgacggtcat gggaaacaac gatgactgta ttttcaaaat caatcaagaa atcttctaac
     3661 catgaaatag attgaatatc aagaccattg gttggctcgt caagtaataa aacgtcaggc
     3721 ttaccaaaga gcgctttagc aagaaggact ttcactttat ctccattagc cagttcactc
     3781 atattttggt agtgaaggtc ttctggaata tttagatttt ggagaagttg agaagcttca
     3841 ctttctgcct cccagccacc taattcagca aagatacctt ctagctcagc ggcacgaacc
     3901 ccatcttctt ctgaaaaatc tgctttcata tagatagcgt ctttttcttt catgatattg
     3961 taaagttgct cattacccat gattacaaca tcaatcgcac gttcttcttc ataatcaaaa
     4021 tgattttggc gaagaacaga taagcgttcg tcaggtccta aagagatatg accagtactt
     4081 ggttcaatat ctcctgcaag gattttaaga aaagttgatt ttccggcacc attcgcaccg
     4141 attaagccgt aagtattgcc ggctgtgaat ttgatattaa catcatcaaa tagttttcga
     4201 tcactaaagc gtagtgatac atcagaaact gtaagcaatt tgtcacctca ttttatttat
     4261 ctaagcttca ttgtacctaa aatagtcccc tttttcaatc agaaaagggc taatcactac
     4321 ataggcaata aaacgtcttt gtcttcacgt ttgtattgtt tagtcaaact aaatcctctt
     4381 cccataactt gagctgctgg catgacaaca ataaaggctg tgtcgtcaat ttcgaggatt
     4441 ttttcttgga gagtgggtaa ttcgtgactt gatacaatag ccattaacat aattttatca
     4501 gaagtagtat aaccaccgcg aataggaagt ttagtcactc cacgatccat aacagttgtg
     4561 atatattctc gaatagcttg ataatctttg gaaataatca taacattttt ggatgagtca
     4621 aagccatttt ccataacgct aatcacataa ccaattacga aaagtccaat cgtagaatac
     4681 atcacgtcat ctgcagaaag tgcaataaat cccataagga cactaatacc atctacaatt
     4741 gtcattgcaa ctccaagaga taaaggagag tatttatgaa gtatttgtgt tagaattcca
     4801 gttcctcctg tcgaagagtt tccccaaaaa accattccta aaccaatgcc acagataata
     4861 ccaccaaaaa tagctgctaa caactgattg tgtgtcagag taggtaatga attggttgaa
     4921 cggatggcaa taggatatat ccaagaacca taaagtgttt taataaaatt ttgttttcca
     4981 agaaagaagt aacacattaa taataaggga atattactag ccattaaaaa aagtgacgga
     5041 ctaatgccaa atagagcttt tataacaact gcaataccaa ccataccccc tgatgcaata
     5101 tgattgtcga caaacattgt attgaaacca atagctgtta tgaatgagcc aattgtgaca
     5161 agtagtaaat caatccctcg ttttttcatg cttttaatct cctttataac tggttaaaaa
     5221 tagtagactc attatctctt aaatgtactg agaccgtcaa gtcatatttt caaaaaatct
     5281 ggtgaacttg acaagaagtt taaaatttca tagaataaat ttgaattaga agagtattct
     5341 tttcatgttt ttagagagtt agtggttggt gcaagctaac aacagaaaag gtgaaatgga
     5401 ctaatgatta tttgaaagga aaccataact ttcaggttgg caccccttac cgtgcagctt
     5461 ctttcattga gaagattgag atagtatctc gttttgataa agcagatgct aattgaggtg
     5521 gtaccgcgta ttacttgtaa taacgccctc acgttttaat agcgtgggga ctttttgcta
     5581 tatcaagaga tagttaggga gaaaatgatg acaaaaccta ttattttaac tggagataga
     5641 ccaactggaa aattacattt aggtcattat gtcggaagtc ttaaaaatcg tgtcttttta
     5701 caaaatgaaa acaagtataa gatgtttgtt ttcttggccg atcaacaggc actgacggat
     5761 catgctaaag aatccgaatt aattcaagaa tctattggaa atgttgcctt ggattacctc
     5821 tctgtcggtt tggatccgaa gcaatcaacg atttttattc aaagtcagat tccagagcta
     5881 gctgaattga gcatgtatta tatgaatctg gtatcattag cacgtttgga aagaaatccc
     5941 actgttaaaa ccgaaattgc tcagaaaggt tttggcgaaa gtattccatc tggttttttg
     6001 gtttatccag tatcacaggc cgctgatatt acagcattta aagcgaattt agtacctgta
     6061 ggtaacgatc agaaaccgat gattgaacaa acacgtgaaa ttgtgagaag ttttaatcat
     6121 acttaccata cagactgttt agtagaacct gaaggtattt atccagaaaa tgaaaaagct
     6181 ggacgcttac ctggtcttga tggcaatgcc aaaatgtcta aatcattggg aaatggaatc
     6241 tatctttcag atgatgcaga taccgttcgc aaaaaagtga tgagcatgta tactgatcca
     6301 aatcatatta aaatagaaga tcctggtcaa attgaaggga atatggtctt tcattatttg
     6361 gatatttttg ctagaaaaga agatcaagct gatatcgaag caatgaaaga gcattatcaa
     6421 agaggtggtt taggagatgt gaaaacgaaa cgctaccttc tagatatttt agaacgtgaa
     6481 ttagcaccta ttcgtgaaag acgtttggag tacgctaaag atatgggaga ggtgttccgt
     6541 atgttacaag aaggtagtca aaaagcaaga actgtggcag ccaagacttt atcagaagtg
     6601 aagtcagcaa tgggtattaa ttatttttaa tgttttagag aaaaagctaa gttagtaatg
     6661 ataagataat tactattatc aaagcaggac ctaatttgtc atttctttac aggatagtag
     6721 agattatgtt ttatatagtc ttatttttga ttaaaaataa gacccaaatg aattttttga
     6781 ttaataaaaa acggataata ctaatatatt atgctgatag tgacttcagc tgtaggaata
     6841 ttttattgac aaatgatttt agcgtgatat gatagtaaca ataaaaaata gaccagggta
     6901 atattcccta aaaataaaag aaaagaggat tgtctggatg tcaaattggg acactaaatt
     6961 tttgaaaaaa ggctacactt ttgacgatgt cttgcttatt ccggcagaga gtcatgttct
     7021 tccaaatgaa gttgatttaa agacaaaact cgcagacaat ttgacattaa atattcctat
     7081 tattacagca gctatggata cggttactgg tagtaaaatg gctattgcaa ttgcgcgtgc
     7141 gggtggttta ggtgttattc ataaaaacat gtctattact gagcaagcag aagaagttcg
     7201 caaggtaaaa cgttctgaaa atggtgtcat cattgatcca ttcttcttaa cacctgaaca
     7261 caaggtttca gaagctgaag aattaatgca gcgctaccgt atcagtggtg tgccaattgt
     7321 tgaaacttta gcaaaccgta agttggtcgg tatcattact aatcgtgata tgcgttttat
     7381 ttctgattac aatgcaccaa tctctgaaca tatgactagt gagcacctcg ttacggctgc
     7441 tgttggtaca gatcttgaaa ctgcagaacg tattcttcat gaacaccgta ttgaaaaact
     7501 tcctttggtt gataatagcg gtcgtctgtc tggtttaatc actatcaaag atattgaaaa
     7561 agtaatcgaa ttcccacatg ctgctaaaga tgaatttggt cgtcttctgg tcgctgctgc
     7621 ggtaggtgtt acctcagata cttttgagcg tgccgaggcc ttgtttgaag ctggtgcaga
     7681 tgcgattgtt attgacacag ctcatggtca ttcggctggt gttcttcgta aaattgctga
     7741 gattcgtgct catttcccaa atcgtacttt gattgctgga aatattgcca ctgctgaagg
     7801 tgcgcgtgct ctttatgatg caggtgttga tgttgttaaa gtgggtattg gtcccggatc
     7861 tatctgtacc actcgtgtgg ttgcaggtgt cggtgttcct caagtgactg ctatttacga
     7921 tgctgctgct gttgctcgtg aatatggcaa aacgattatt gctgatggtg gtatcaagta
     7981 ttctggcgat attgttaagg ctcttgcagc cggcggtaat gctgttatgc ttggatcaat
     8041 gtttgcaggt actgatgaag ctccaggtga aactgaaatc taccaaggcc gtaagttcaa
     8101 aacttatcgt ggaatgggtt ccattgcagc tatgaagaaa ggatcaagcg atcgttactt
     8161 ccaaggttcc gtaaatgaag ctaataaact agttccagaa ggtattgaag gccgtgttgc
     8221 ttataaagga gctgcttcag atattgtctt ccaaatgtta ggtggtatcc gctcaggtat
     8281 gggctatgtt ggcgcaggtg acattcaaga attacatgaa aatgctcaat ttgttgaaat
     8341 gtcaggtgca ggcttgattg aaagtcatcc gcatgatgtc caaatcacaa atgaagcacc
     8401 aaactattct gtgcactgat aatttaattt agtaacttta agggctgaca tattgtgcca
     8461 gctctttttt tatattaaa
//
LOCUS       DATWEK010000054         8476 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.054, whole genome shotgun sequence.
ACCESSION   DATWEK010000054 DATWEK010000000
VERSION     DATWEK010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8476
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.054"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            66..248
                     /locus_tag="VCR92_001664"
     CDS             66..248
                     /locus_tag="VCR92_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268715.1"
                     /translation="MTSVRTAQLLNNGLGLVGQDLKDVLSALANSVNPSIEKQISHIM
                     IDRANTGEWLANVGKK"
     gene            260..592
                     /locus_tag="VCR92_001665"
     CDS             260..592
                     /locus_tag="VCR92_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268716.1"
                     /translation="MKYRVETNPFSKDRYTPEQLEMFKNRQLSKNKAEAYFTRLYNQH
                     IAWVIIANVMTEYVNKFRKSATSFEKAWDALGYQQTTEIVFRAVNGLPCSEKDTGELE
                     TYLSEVSA"
     gene            592..783
                     /locus_tag="VCR92_001666"
     CDS             592..783
                     /locus_tag="VCR92_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268717.1"
                     /translation="MQELNLTPTQTLILFIVLGLVGLLLSLSKPLIEIDLPEDTQVPK
                     PPQNANYGAYIQSQNHYYN"
     gene            692..1060
                     /locus_tag="VCR92_001667"
     CDS             692..1060
                     /locus_tag="VCR92_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268718.1"
                     /translation="MTYQKIPKYLNHLRTQTMGLIFNHRTIITIRREQMQLLSREAEL
                     ELLEKVGCYLEKRWQLELENKDDWDLIPRQDLLEKLDITGTTLKNWEKEGLKSYQSPF
                     ENSKKVYYRKSDIYNFLSVD"
     gene            1070..1591
                     /locus_tag="VCR92_001668"
     CDS             1070..1591
                     /locus_tag="VCR92_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268719.1"
                     /translation="MDYLEVTMTKDCVKIFNFLYKYPTKAYQKDEYFKLLYMHPLDSF
                     LTSFSLSGIRVKVTDKPVLAGWKLVRDIEVRIATGELLEMIEELEICYLRKHQTVSYV
                     EIKFYVVHLLTYGIRSRYDMQFFTKLLFCCGYDQETVIGIYSNITKNTRLSRDFITLQ
                     AKLYQTKKGTHEH"
     gene            1581..3194
                     /locus_tag="VCR92_001669"
     CDS             1581..3194
                     /locus_tag="VCR92_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage resistance protein"
                     /protein_id="HEP4268720.1"
                     /translation="MSIKENIDKLVSMEWTESIFGQSKMKADYKRQLSKVIELDTLSN
                     IHHNGETYAVSNQEVMYLSESKGRTHKFISGNVKTKSKGKGRDSQKYLVVSFDHQFPP
                     FAKLVVDYLLGRFTFFNNKLYDVNNRQAQVLDDFTIQSLYGFKKDNPFILEILEGIHQ
                     TLNIRPAKQLEAYKISGRDFIIDLKEHRLYRTNPSSDSSFFKFYDVDYHTAIGSKKKV
                     GKFLDYVIADHDSLHNATLQAYYIAQVACGLKSKQNFFISKSGVRTGKGLRHIGLSGI
                     FNKIDVELDLLIKGGFEASNAWGAFAGGEMALATEQGDIVGDKMERVLKIIATEKTHM
                     ARSIGGNLGTVNLTSVLCIDTNRTVALSDEMNGRAVLIQYQNRPEEETDLEREKAFEE
                     YWQTFTEMDKSPKIEGVIGFLLVSLDYFRKNDMKFDWRAVEVVNDDDLDDFQVYLINH
                     LSEKDFVERDSYVRELYNSTYGKNNNQAGQRMRTIGVKSYRKQTTGGRKIPGYKVDNI
                     KRFNKFSGGEKENTNIFDMFEKLNQPLPP"
     gene            3481..3654
                     /locus_tag="VCR92_001670"
     CDS             3481..3654
                     /locus_tag="VCR92_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2758 domain-containing protein"
                     /protein_id="HEP4268721.1"
                     /translation="MKIKLFYQKHNESLDDFEYRVNQFTLSVSVIDIKLSEATYGNYE
                     DMSTTTSLLVLYR"
     gene            3660..3833
                     /locus_tag="VCR92_001671"
     CDS             3660..3833
                     /locus_tag="VCR92_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001873750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268722.1"
                     /translation="MKLKLHTRGGNTITIQGDSAFYDELVKYLLSGRQPNWVTCPSAV
                     INLSDIIAITKEK"
     gene            3835..4161
                     /locus_tag="VCR92_001672"
                     /pseudo
     CDS             3835..4161
                     /locus_tag="VCR92_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001258765.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4157..4402
                     /locus_tag="VCR92_001673"
     CDS             4157..4402
                     /locus_tag="VCR92_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268723.1"
                     /translation="MSNQMAVFNQFWAYQTLFQPTAQDIKLAILGYFTGTLWACEVSV
                     LEDVELGYRVIVSYVSCFDKSDRLLKIAQAVENSQLG"
     gene            4416..4574
                     /locus_tag="VCR92_001674"
     CDS             4416..4574
                     /locus_tag="VCR92_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268724.1"
                     /translation="MQTEVKDGFIYFKENGRIGVVEIPTFGKLTLSSKEGYIHQVDHS
                     FSTKHNQK"
     gene            4665..5453
                     /locus_tag="VCR92_001675"
     CDS             4665..5453
                     /locus_tag="VCR92_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268725.1"
                     /translation="MYKQTNKTYADILEKVEAATAQWIIRKKASSLKDDVIITDEDIQ
                     AEKERIFIEKYGTALFDFKIDSYRKELDDLKIKAREQVNQFNDFVKELEQDDRYTERG
                     KVDLYRAERKKAEKTLKEIGEAQHKLNVDIQKIEVESAQNAWKKLESEMTPDSITPSE
                     YQYLEMMLSRNDSDEMRKKLAEKFHYHLMVLEYLNADRKFGEVIIKHPLEGVKNQSVN
                     YIKIGDVRLPEVYESTYIHELLKHYKNDIYFGESYANHEWDEEQ"
     gene            5450..5716
                     /locus_tag="VCR92_001676"
     CDS             5450..5716
                     /locus_tag="VCR92_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268726.1"
                     /translation="MMSLECLRIYLKKSQFTELEHLLFRIIVLGGYPDDMYFPSRVRT
                     IITSLVNNIRKNLDSEGYRSVEELEEAIEKAISEHDEITQKGGG"
     gene            5758..6096
                     /locus_tag="VCR92_001677"
     CDS             5758..6096
                     /locus_tag="VCR92_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEP4268727.1"
                     /translation="MVAMVTSKTITEAAERAGITRGTAHRYLKDITFKKACRRYRSEL
                     MQQTTSLLQSASIEAVEVLRNIMLDDSISPYARQQSAQTILSTAYKAHELDDIVEMVE
                     ELEARFEDEQ"
     gene            6086..6361
                     /locus_tag="VCR92_001678"
     CDS             6086..6361
                     /locus_tag="VCR92_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268728.1"
                     /translation="MNSNLKKRVDKLRRLHSLDNASGIVFVEYADGKYQIKKQDHVPK
                     FIETRLIAEFESEEEAENFLSTIPSGYIIFWDIFPEEVEHVKKNKYL"
     gene            6336..6581
                     /locus_tag="VCR92_001679"
     CDS             6336..6581
                     /locus_tag="VCR92_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268729.1"
                     /translation="MLKKINTYRRLEIIKNKLDEASKDSIEDIMLDWFRALHYALKVD
                     DTIDLPTFLEFKDNKALRDKIMADLGDFDPFEDLNIE"
     gene            6862..7209
                     /locus_tag="VCR92_001680"
     CDS             6862..7209
                     /locus_tag="VCR92_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEP4268730.1"
                     /translation="MNAKEQLKELKPLFALMTLFEEQRDKDIKLMNAFRNPELLNGIE
                     KGTAKQLLYLAKERDKRLAMIATLQDERQIAVIKARYVDDLSWDEIPDKLGYSRNTVF
                     KLHREALEVLDEP"
     gene            7199..7570
                     /locus_tag="VCR92_001681"
     CDS             7199..7570
                     /locus_tag="VCR92_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEP4268731.1"
                     /translation="MNHKNAIRKLKEFHRWQRIANSLNLTYNECYQFDIEYYSFRRKH
                     LEISRKCALEELDAIKHAINQLSKIEYRKILIECYLIGEKKPQQDIIAELNRSKSWYY
                     ETKRRALLEFVEFYRDGVLKK"
     gene            7723..7950
                     /locus_tag="VCR92_001682"
     CDS             7723..7950
                     /locus_tag="VCR92_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation repressor RelB"
                     /protein_id="HEP4268732.1"
                     /translation="MAMVSLRLNSAEEELFRSYATHTGKTLSELFKTALAQQIEDQLD
                     YETGIQALKRFEENPITYSIDDLIEELENDL"
     gene            7940..8209
                     /locus_tag="VCR92_001683"
     CDS             7940..8209
                     /locus_tag="VCR92_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEP4268733.1"
                     /translation="MTYKLVVSDEVKKQLKKMDKHVGLMLAKDMKKRLDGLNNPRQFG
                     KALTGQYKGLWRYRVGNYRVICDIVDNEMIILALEVGHRKEIYKR"
BASE COUNT         2999 a         1377 c         1717 g         2383 t
ORIGIN      
        1 tagcatgaat ctagtataag aaacaagcaa ctacacagaa aataagaatt aataaggaag
       61 ataaaatgac atcagttaga accgcacaat tacttaacaa tggtttagga ttggttggtc
      121 aagacctaaa agacgtctta tcagctctag ccaatagcgt caatccaagt attgaaaaac
      181 agatttctca catcatgata gatagagcta atactggcga atggttggca aatgtaggca
      241 aaaaatgagg taagacataa tgaaatatag agtagaaaca aatccttttt caaaagatag
      301 atacactcct gaacagctag aaatgttcaa aaatcgacaa ctcagcaaaa ataaagcaga
      361 agcctatttc actcgactat ataaccaaca tattgcttgg gtgattattg ctaacgttat
      421 gacagaatac gtcaataaat tcagaaaaag tgccaccagc tttgaaaaag catgggacgc
      481 tttaggctat caacaaacca cagagattgt ctttagagcc gttaacggtt taccttgttc
      541 agagaaagac acaggggaac tagaaactta tttaagtgag gtatcggcat gatgcaagaa
      601 cttaacctca caccaacaca gacacttatt ttattcattg ttttagggct tgttgggctt
      661 cttcttagcc tttctaagcc attaatagag attgacttac cagaagatac ccaagtacct
      721 aaaccacctc agaacgcaaa ctatggggct tatattcaat cacagaacca ttattacaat
      781 taggagggaa cagatgcaat tattatcacg agaagcagaa ttagagctac tagagaaggt
      841 gggctgttac cttgaaaaac gttggcaact tgaactagaa aacaaagatg attgggattt
      901 aattccaagg caagatctac tggaaaaact agacattact ggtaccacgt taaaaaattg
      961 ggaaaaagag ggcttaaagt cgtatcagtc gccattcgag aacagtaaga aggtgtatta
     1021 ccgtaaaagt gatatttata attttttgag cgttgactag gaggactttg tggattattt
     1081 agaggtcacc atgacaaaag attgcgtaaa aatattcaat tttttgtata aatatcctac
     1141 caaagcatac caaaaggacg agtatttcaa attactgtat atgcatccct tggacagctt
     1201 tttaacaagt ttctccctat cgggcatccg agtgaaagtt acagacaaac ctgttttagc
     1261 agggtggaaa cttgttaggg atatagaggt tagaattgct acgggggaac tcttggaaat
     1321 gattgaagag ctagaaatat gctatttaag gaagcaccag acggtttctt acgttgaaat
     1381 taagttctat gtcgtccatc tattgactta tggtattagg tcacgttacg atatgcaatt
     1441 ttttaccaag ttgttgtttt gttgtggtta tgatcaagaa actgttatcg gtatttatag
     1501 caatataacc aaaaatacca gactttcaag ggattttata actttacagg ctaaacttta
     1561 ccaaacaaag aaaggaaccc atgagcatta aagaaaacat tgacaaatta gtatctatgg
     1621 aatggactga atcaattttt gggcaatcta aaatgaaagc agactataaa cgccaactat
     1681 ctaaggtgat tgagttggat accttaagca atatacacca taatggggaa acctatgctg
     1741 tttcaaatca agaagtcatg tacttaagtg agagtaaagg tagaactcat aagtttattt
     1801 caggaaacgt taaaacaaaa tctaaaggaa agggaagaga tagccaaaag tatctcgtgg
     1861 tttcctttga ccatcaattc ccaccttttg ctaagttagt ggttgattat ctacttggac
     1921 gatttacttt ttttaataac aaattatatg atgttaacaa tcgtcaagcg caagtgttag
     1981 atgatttcac tattcaatcg ttatacggct tcaaaaagga taacccgttc attttagaga
     2041 ttctggaagg aatccaccaa accttgaata ttagacctgc gaaacaactt gaagcttata
     2101 agatttctgg gagagatttc attattgatc ttaaggaaca tcggttatac cgaacaaatc
     2161 ccagttccga tagttctttc tttaagtttt atgatgtcga ttatcacaca gcgatcggta
     2221 gtaagaaaaa agttggcaag tttttagatt atgttatcgc agaccatgat agcttgcaca
     2281 atgcaacgtt acaagcctat tatatcgcac aggtcgcttg tggactgaaa tcgaaacaaa
     2341 atttctttat ctctaaatct ggtgtgagaa ctggtaaagg cttaagacat attgggctta
     2401 gcggtatctt taataaaatc gatgttgagt tagacttatt gattaaaggt ggctttgaag
     2461 ctagcaatgc ttggggtgct tttgctggtg gagaaatggc tctagcaaca gaacaagggg
     2521 atattgtagg cgataaaatg gagcgtgtgc ttaaaattat tgctactgag aagacccata
     2581 tggctagaag tatcggtggc aatttaggaa cagttaattt aacaagtgtt ctgtgtattg
     2641 acacaaaccg cactgttgcg ctgtcggatg aaatgaatgg tagggcggtt ttgatccaat
     2701 accagaatag accagaagag gaaactgatt tagaacgtga aaaggccttt gaagaatatt
     2761 ggcaaacctt cactgaaatg gataaaagcc ctaaaattga aggagtgata ggttttttac
     2821 ttgtatcact tgattacttc cgaaaaaatg acatgaaatt tgattggaga gcggtcgaag
     2881 tggtgaacga tgatgattta gatgattttc aagtttacct gattaaccat ctttctgaaa
     2941 aagactttgt agagcgtgac tcttatgtta gagagctgta taactctact tacgggaaaa
     3001 ataacaacca agccggccaa agaatgcgga cgataggggt taagagttat cgcaagcaaa
     3061 caactggagg acgcaaaata cccggctata aagtcgataa tataaaacga tttaacaaat
     3121 tctcaggagg agaaaaagaa aatactaata tctttgatat gtttgaaaag ctaaaccaac
     3181 cactaccgcc atgacccaga cagtaggggt tgtggggggt ataaacccag tggtatcaag
     3241 ggatagagta caatcaccca taaccaccta taactatata ggggagagag aattattttt
     3301 ttagtagata tgttatttct ttacattatt tttatttttt ctcccttatc tatatagaaa
     3361 agtggcggta ggtggtggtt gtgctggcaa atggctcaac catgcggttt taagcacacc
     3421 accactttat ttagggttgt gtctacaccc accactttga gccaaaacag gagaaaaaac
     3481 atgaaaatca aactatttta tcaaaaacac aatgaatctt tagatgattt tgaatatcgg
     3541 gtcaatcaat ttaccctatc agtatctgta atagatatca aactttcaga agcaacttat
     3601 ggcaattatg aagacatgag taccacaact tctttactgg tcttgtacag gtaactgata
     3661 tgaaactaaa attacacaca cgaggcggca acaccatcac catacaagga gacagtgcct
     3721 tttatgatga gttggtcaaa taccttcttt ctggccgaca accaaactgg gtaacatgtc
     3781 cttctgccgt catcaattta tcagacatta tagcaatcac aaaggagaaa taatatgaga
     3841 acattttcag acacaccaaa aacattcaca tttcactaca cgtttaaaga ctttgacacc
     3901 gcacaagtag cctgtcacgc cattctaggc tatatgactg gtacttatga gcaaccagtg
     3961 attgatgcca cctatcacaa tgataatcaa ggcgggcatg ctaatcagtt agtattagaa
     4021 tatgccgagg acagaaagtt aagcaaggtc ttcaagcgta tctgtgacag cttcaaggat
     4081 tattacaacc aacctgagga tatgacggat gaagaacttg atgacatggt tcaagaaaat
     4141 gaattaatca aggaagttga gcaaccagat ggcagtattt aatcaatttt gggcgtatca
     4201 gacacttttt caaccaacgg cacaagatat taagttagct attttaggat acttcacagg
     4261 cacgctatgg gcttgtgagg tgtccgtgtt ggaagatgtt gaacttggct accgtgttat
     4321 cgtctcttac gttagttgtt ttgataaaag cgatagactg ctgaaaattg ctcaagcagt
     4381 tgagaatagt cagttaggat gaaaggaggt atttaatgca gacagaagtg aaagatggct
     4441 ttatttattt caaagaaaat ggtagaatag gagtagtaga gatacctact tttggtaagc
     4501 taaccctatc tagcaaggaa ggctatattc atcaagtaga ccacagcttt tctactaaac
     4561 acaatcaaaa ataattatac tgaccgaaga acggaggtat attcatgaag cttaatggct
     4621 tttttggata tacctctttt tgcatttaag aaaggaaaga cacgatgtac aaacaaacta
     4681 acaaaactta cgccgatatt ttggaaaaag ttgaagccgc aacagcgcaa tggattatta
     4741 gaaaaaaagc ttcaagcctt aaagatgacg tgattatcac tgatgaggat atacaagctg
     4801 agaaagagcg tattttcatt gagaaatatg ggacagcact gtttgatttt aaaattgata
     4861 gctaccgtaa agaattagat gatttaaaaa tcaaagctcg tgagcaagta aaccaattca
     4921 atgattttgt aaaggaacta gaacaagacg accgttacac agaacgtggt aaagtggatt
     4981 tataccgagc agagcgaaaa aaagctgaaa agacccttaa agagattgga gaagctcagc
     5041 ataaacttaa tgttgatatt caaaagattg aagtagaatc ggctcaaaat gcttggaaaa
     5101 agttagaatc tgaaatgacg cccgattcaa tcacccctag tgaatatcag tatttagaaa
     5161 tgatgttatc acgtaatgat agtgatgaaa tgcggaaaaa acttgctgag aagttccatt
     5221 accatctgat ggtcttggag tatttgaatg ctgaccgtaa atttggagaa gttatcatca
     5281 agcacccatt agaaggggtt aaaaatcagt cagttaatta tattaaaatt ggggatgtcc
     5341 gattgcctga ggtttacgaa agcacttata ttcatgaact tttgaagcat tacaagaatg
     5401 acatttactt tggcgagagc tacgcaaatc atgaatggga tgaagagcaa tgatgtcatt
     5461 ggaatgttta agaatatacc ttaagaaaag ccagtttaca gagcttgaac acttgctatt
     5521 cagaattata gtgttagggg ggtatcctga tgacatgtat ttcccctcaa gggttcgtac
     5581 gatcatcaca agcttggtta ataatatacg taagaattta gattctgagg gttaccgtag
     5641 tgtcgaagaa ttggaagaag ctatagaaaa ggctatttca gagcatgacg aaatcacaca
     5701 aaaaggaggg gggtgatttt tatagaacat ggtttaacac ctaaacaaga gaaattcatg
     5761 gtagcaatgg tgaccagtaa aactatcacc gaggcagccg aaagagcagg tatcacaaga
     5821 ggaactgccc atagatacct taaagacatt actttcaaaa aggcttgtcg ccgttatcgt
     5881 agtgagttaa tgcagcaaac cacatcctta ttacagagtg ccagcattga agccgttgag
     5941 gtgctacgta acattatgtt ggatgattct attagtccat atgcaaggca acaatcagcc
     6001 caaactatct taagcactgc ttataaagcg catgaactag atgatattgt tgaaatggtt
     6061 gaggaactag aagcgagatt tgaagatgaa cagtaactta aaaaagcgag ttgataagtt
     6121 aaggcgacta catagtttag ataacgcttc tggtattgtc tttgtagaat acgcagatgg
     6181 caagtatcag attaaaaaac aagatcatgt ccctaaattc attgagacta gacttatagc
     6241 agaatttgaa agcgaagaag aagcagaaaa ctttttaagc actattccaa gtggttacat
     6301 cattttttgg gatattttcc ccgaagaggt tgaacatgtt aaaaaaaata aatacttata
     6361 gaaggctcga aatcatcaag aataagctcg atgaagcgag taaagatagt attgaagata
     6421 taatgctgga ctggtttagg gctttgcatt atgctcttaa agtagatgat acaattgatt
     6481 taccaacgtt ccttgaattt aaggacaaca aggcattgag agataaaata atggcagacc
     6541 ttggagattt tgacccattt gaagatctaa atatagaata gttaaatggt gacagcatcg
     6601 ccacaaggtc gtcataagga gatagttttt tgactgtctc cctttttcgt catctattcc
     6661 ccatcagact aaaataaaac atggttttag cgcttctgtc tgctaagttg atgattttat
     6721 attataagct ctgaaaagcg cttagaaacg attttagagc cgttcttccg ctatcaagaa
     6781 tgactaaaac aaaaagacgt ccacacggaa cgccttcatg attatatctg ttaacacaat
     6841 tataccacac tgggggcttt catgaacgcc aaagaacaac ttaaagaatt gaaaccactt
     6901 tttgctttaa tgaccttatt tgaggaacaa cgagacaagg acatcaagct aatgaatgct
     6961 tttcgtaatc ctgagttact aaatggcatc gaaaaaggta cagctaaaca acttttatat
     7021 ttagctaagg aacgtgataa gagactagcc atgattgcca cattgcaaga tgagagacag
     7081 attgccgtta tcaaagctag atacgtggat gacttatcat gggatgagat acctgataaa
     7141 ctaggttatt caaggaatac cgtttttaaa ttacatagag aagctttaga ggtattagat
     7201 gaaccataag aacgctattc gtaaactaaa agagtttcat agatggcaac gtatcgctaa
     7261 tagccttaat ttaacctata acgagtgtta ccagtttgat atagaatatt attcctttag
     7321 acgtaaacac cttgaaataa gccgaaaatg cgccctagag gagctagatg ctattaagca
     7381 tgccattaat caactatcta agatagagta tagaaagata ctgattgagt gttacttgat
     7441 cggtgagaaa aaacctcaac aagacatcat agcagaactt aacagaagta aaagctggta
     7501 ttatgagact aagagacgtg ctttacttga atttgtggaa ttttacagag acggtgtgct
     7561 aaaaaaataa tgttcgttta tgataacaga gcaatagata taaatgttaa taatacagtg
     7621 ttagaagagc ttaacaaggt atatcaatac gggtaaataa ttgactgatt cctccttatg
     7681 ttatacaatg tattacagat aaacaaacag aggtggaaga atatggcaat ggtatcatta
     7741 agactgaaca gcgcagagga agaacttttc agaagctacg ctacacacac aggcaaaaca
     7801 ttatctgaat tattcaagac agcactagca caacaaattg aagatcaatt ggactatgaa
     7861 acaggtattc aagctttaaa acgctttgaa gaaaatccca taacttattc tatcgatgat
     7921 ttaattgagg agttggaaaa tgacttataa gctagtggtg agtgatgaag tcaagaagca
     7981 actcaaaaag atggataaac atgtagggct tatgttagcc aaagacatga agaaacgact
     8041 tgacgggtta aataatccta gacaatttgg aaaagccctc acaggtcaat ataaaggact
     8101 ttggcgctat cgtgttggta attatcgggt gatttgtgac attgtggata atgaaatgat
     8161 tatccttgct ttggaagttg gacacaggaa agagatatac aagcgctagc aaatacaaga
     8221 catggtacga ggtataataa aaagcgcagc taatgaccac gctatttctt gcttactgaa
     8281 ctcattattt taattccttt ttagttaccc tttagatttc tgatagtgta tctagtttac
     8341 actgttttta gagaaataag agtgataact cacttggttt acagctactt tacactacta
     8401 aatatgagta gtataacaaa atgctttaat tttaagatta aacttacaaa aagcctattt
     8461 gataggcttt ttttgt
//
LOCUS       DATWEK010000055         7269 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.055, whole genome shotgun sequence.
ACCESSION   DATWEK010000055 DATWEK010000000
VERSION     DATWEK010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7269
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.055"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(45..260)
                     /locus_tag="VCR92_001684"
                     /pseudo
     CDS             complement(45..260)
                     /locus_tag="VCR92_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(458..802)
                     /locus_tag="VCR92_001685"
     CDS             complement(458..802)
                     /locus_tag="VCR92_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268734.1"
                     /translation="MLRTNTIAGNFFIDGQQQKTLINPIKIDKDIVTIQEFDFKIRKF
                     LMESKEIHLTKSPYIRGSLEIHSKNRKHEKINLYDAKPNSTRSDVLKKYKDNKTINMK
                     DFSHFDIYLWTK"
     gene            complement(843..1868)
                     /locus_tag="VCR92_001686"
     CDS             complement(843..1868)
                     /locus_tag="VCR92_001686"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922160.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEP4268735.1"
                     /translation="MRKRCYSTSAAVLAAVTLFALSVDRGVIADSFSANQEIIYSEVT
                     PYHVTSVWTKGVIPPANFTQGEDVFHAPYVANQGWYDITKTFNGKDDLLCGAATAGNM
                     LHWWFDQNKEKIEAYLKKHPDKQKIMFGDQELLDVRKVINTKGDQTNSELFNYFRDKA
                     FPGLSARRIGVMPDLALDMFINGYYLNVYKTQTTDVNRTYQEKDRRGGIFDAVFTRGD
                     QSKLLTSRHDFKEKNLKEISDLIKKELTEGKALGLSHTCANVRINHVINLWGADFDSN
                     GNLKAIYVTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQ
                     DSWNQTN"
     gene            2372..2574
                     /locus_tag="VCR92_001687"
                     /pseudo
     CDS             2372..2574
                     /locus_tag="VCR92_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
     gene            2776..3156
                     /locus_tag="VCR92_001688"
     CDS             2776..3156
                     /locus_tag="VCR92_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEP4268736.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDE
                     QQKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGIHLEFKN"
     gene            3156..4004
                     /locus_tag="VCR92_001689"
     CDS             3156..4004
                     /locus_tag="VCR92_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEP4268737.1"
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLS
                     IDDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQF
                     LAEEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEIL
                     NDLIADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAF
                     GVTPRL"
     gene            4129..5337
                     /locus_tag="VCR92_001690"
     CDS             4129..5337
                     /locus_tag="VCR92_001690"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEP4268738.1"
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIH
                     DVDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLEQKRLRAVGKAEERFEEDA
                     LRIMRGFRFAASLDFDIEAATFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGIS
                     AMIACQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLK
                     AWKTSNDFQRYVTKLIALYRIRQERSFEKLDIYQYGKEMASLVEGLRKAQSLSVDMDH
                     IEALDQALAIHNKYDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTI
                     EAFVREELAT"
     gene            5334..7211
                     /locus_tag="VCR92_001691"
     CDS             5334..7211
                     /locus_tag="VCR92_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEP4268739.1"
                     /translation="MSHFLVKKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTT
                     LLDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDASSVLDTVLSSDVKAIQLIRQ
                     YELLMANYTEDKQETLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGM
                     RRRVQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHV
                     ATRIFELDKAGLTEYQGNYQDYVRLKAEQDERDATNLHKKKQLYKQELAWMRTQPQAR
                     ATKQQARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKD
                     FNLIIQNKDRIGIVGDNGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMD
                     ETKRVINYLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLK
                     LLIEKPNVLLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKVATKILAFE
                     EGDIRIFYGSYSDYLDEKAFEKETVEADLAKAIVTEEVPLPPKEEKKRMSYLEKQEWA
                     QIEDKIATIEANIEEIENQMLTVVSDYGQLAQLQKELDQRNNDLLLAYERFEYLSGLD
                     I"
BASE COUNT         2313 a         1191 c         1472 g         2293 t
ORIGIN      
        1 atatgtttat cgttgtaata atcaatgtca tttgtaatcg cttattctga gtcttctagt
       61 gatttacagt tattctcata accatagaac atttctgatt ttaagatgcc aaagaaagat
      121 tccatcatgc cattgtcagg cctgtttctt ttacgtgaca tagacggacg aattccttta
      181 gagtttagga aatgatgata atagttgtgt tgatattgcc aaccttgatc actctatcat
      241 atagttccgt catagcattt atttggagat gcctttttcc attattggtt taatgtgatt
      301 taagcaaggt tattagctaa acttaatgcc agacaaaaac accccaatta ttagattttt
      361 tgtctaactt ttggggcgca attcaatctg agcagtttta gatttggtat caatgttatt
      421 ataggtcaat tgatcatatt tatccagagc ttttagctta tttagtccaa agataaatat
      481 caaaatggct gaaatctttc atgtttatag tcttattgtc tttatatttt tttaagacat
      541 cagatctggt gctattgggt tttgcgtcat ataaattgat tttttcatgt ttcctatttt
      601 tactgtgaat ttctaaactc ccccttatat aaggagactt agtcaaatga atttcttttg
      661 attccatcaa aaattttctt attttaaaat cgaactcttg aatcgtaaca atatccttat
      721 cgatttttat aggatttatt aatgtttttt gctgttgccc atctataaaa aaattccctg
      781 caatagtatt agtccttaga ataccatcat ctgttgaatg taatctttct tattgatacg
      841 ctttaattgg tctgattcca actatcttgc cctgttgaaa gtgtaaataa ccctagtact
      901 tgagcaccaa tattatcttc ttttatttct ttagcagaaa tagctacttt tccagcggag
      961 ttaacaccaa caaagtattt cttcatacca atagatgcat tactatcaga gtctgttaca
     1021 taaatagctt taaggttccc gttagaatca aagtcagctc cccacaggtt tataacatgg
     1081 ttgatgcgta cgttagcgca ggtgtgtgat aggcctagag ccttgccttc ggttaactct
     1141 ttcttaatga gatcactgat ttctttgaga tttttttctt taaaatcatg acgacttgtc
     1201 aatagcttac tttgatcacc tcttgtaaat acggcgtcaa aaataccacc tcggcgatct
     1261 ttctcttgat aggttctatt gacatcagta gtctgtgtct tataaacatt taagtaataa
     1321 ccattgataa acatatctaa agcaagatca ggcataactc caattcggcg tgctgacaaa
     1381 ccggggaaag ctttatctcg gaaataatta aaaagctcgc tatttgtttg gtcaccttta
     1441 gtattaataa cttttcttac atccaataat tcttgatcac caaacatgat tttttgttta
     1501 tctgggtgtt tttttagata tgcttcaatt ttttctttgt tttgatcgaa ccaccagtga
     1561 agcatattcc ctgctgtggc agccccgcaa agaagatcgt cttttccatt gaatgttttg
     1621 gtaatatcat accatccttg gttagcaaca taaggagcgt gaaaaacatc ttcgccttga
     1681 gtgaagtttg ctggaggaat aactcctttg gtccaaacgg aagtaacgtg ataaggtgtt
     1741 acttccgaat atataatctc ttgattagca gaaaaactat ctgctataac accacgatct
     1801 accgatagag caaataaagt cactgctgcc aatactgcag ctgaagttga atagcatctt
     1861 tttctcataa gaataccttt ttctatataa ttttattata aaaagattat aacatataga
     1921 catctattgt tgcaattttt taaaataata cttaattttt taaataattt ttaataaacg
     1981 taaacaagcg attgacaatg gagatatcac aagagataca gtagtggttg tgcttaaaat
     2041 ggacggtttt ttgatgatat gttgccgcat gaggaagtga gcaataggag agctgtgata
     2101 gaagaaagag aggaagaagc gttgatgaaa ttagacaaat aaaaaaaaag acctcatcca
     2161 gaagaggtcg tggtataact ggggacgata ggttcaattg ataaaaaatc ttgttagctt
     2221 acgatctatg ttgttttgaa tgcctttaac tcaacatcgt taatggattt tgagataaaa
     2281 aaataaatcc aatagtctgg tactttccta ttttttgtct gttaaaacgt ttttatttta
     2341 taatggataa aaggagaaga agggcggagc gatgattaag ctctatgggt ttaagtatgg
     2401 gttagttgga gaggttttgc ggcggattga acgcctagga tttacgtttg agcgattaga
     2461 gctaagacaa gctagttcga aatacttggc taagcatgat gaggccttgg tgataaacct
     2521 ttttatcctg gacttaaaac ttacctgacc agtggttctg ttttaattga ggtgcagtac
     2581 aagaccacta acgggtgttt ttttgatata atgtcagtat aaggacgact aaatataaat
     2641 aggtgaaaaa atagatatct gttcgagaga tagcactgtt taaaacgtta tgcgaaaata
     2701 gtagtttagg ggctacttta ataatcttca aatctatgct ataatggatc atattgatac
     2761 caaggagaat aaaaaatgca attagttcgt gaaaaagaat ttgtcaacca gtaccattat
     2821 gatgctagaa atttagagtg ggaaaaagaa aacggaacac cagagaccaa ttttgaagtg
     2881 acttttcagt tgattgataa agatgagcag caaaaagaaa cagtaattgt atctgtattg
     2941 caatttgtta ttgtcaaaga agaatttgtt attagtgggg tcatctcaca aatggttcgt
     3001 attttagatc gtttagtgga taaaccaagc gaatttacgc aagaggaagt tgaatcctta
     3061 gctgctcctt tgctagacat ggttaagcga ttgacttatg aagtcacaga aattgccttg
     3121 gatcgtccag gtattcattt ggagtttaaa aattaatgaa attagcagta attactgaca
     3181 gtacagcaac actaccaaca gatctgaaac aagataaagc tatttttagc cttgatatac
     3241 cagttatcat tgacgatgag acctattttg aaggtcgaaa tttgagtata gatgattttt
     3301 atcaaaagat ggctgactcc caaaatcttc ccaagacaag tcagccaagt ttatctgaac
     3361 tagataatct tttaggactt ttgtcttcta agggctatac acatgttatt ggcttgttct
     3421 tagctggagg aatctcaggc ttttggcaaa atattcaatt tttagctgaa gaacatcctg
     3481 agattgaaat ggcatttcca gacagtaaga tcacatctgc tcctttaggt agtatggtaa
     3541 aaaatgtgct agattggtca cgtcaaggaa tgacatttca agctatttta aacaagctgc
     3601 aagaacagat tgatgggacg acagccttta ttatggttga tgaccttaat catctggtta
     3661 aaggcggacg cctgtcaaat gggtctgctc ttcttggaaa tcttttgagt attaaaccta
     3721 tcttacgctt tgatgaagag ggaaaaatcg ttgtttatga aaaagtgaga acagaaaaga
     3781 aagccatgaa acgcttggtt gagattttaa atgacttgat agcagacggt cagtataatg
     3841 tgtctattat tcactcaaaa gcacaagaca aagctgatta tttgaaacga ctcttacaag
     3901 acagtggtta tcaatatgac attgaagagg ttcattttgg agcggtgatt gctactcatt
     3961 taggagaagg agccattgca tttggcgtaa caccgaggct ttaattgtcg attagaaaaa
     4021 atagttaatt gcaagaatca ctaaaacaat aacaaaatgt gatagaaccc aagtagccta
     4081 atcacacttt agattgggct acttggatga taggttagaa aacaacgtat gaaattaatg
     4141 acaatgcctt ctgagtttca gaaggcttta cccatattga ctaaaataaa agaagctggt
     4201 tatgaagcct actttgtggg aggaagcgtc agagatgttt tactcgagcg tcccattcat
     4261 gatgtagata ttgcaactag ttcctatcct gaagagacta aagcgatttt taacagaact
     4321 gtcgatgttg gcattgaaca tggtacagtg ctcgtgcttg aaaatggcgg tgagtatgaa
     4381 atcacaacct ttaggacaga agatgtctat gttgactatc gccgtcctag tcaggtttct
     4441 tttgtgcgct ctttagagga agacttaaaa cgaagagact ttaccgtcaa tgccttggcc
     4501 ttggatgaaa atggtcaagt tattgataaa tttagaggac tcattgattt ggagcaaaaa
     4561 cggttacgag cagtgggtaa agcagaggaa cgttttgaag aagatgcact acgcattatg
     4621 agaggctttc gatttgcggc gagtctggat tttgacattg aagctgcaac ttttgaagct
     4681 atgaggagcc attcacctct attggaaaag atttctgtgg aacgttcttt tactgaattt
     4741 gataaattat tgatggcacc gcactggcga aaagggattt ctgccatgat tgcttgtcag
     4801 gcttatgact atttaccagg cttgaagcag caggaagcag gcttgaatca tctgatagtt
     4861 tctttgaaag ataactttac ctttagtgat caccaccaag cttgggctta tgtgatgatt
     4921 agtttagcca ttgaggatcc taaaagcttc ctaaaagcat ggaagacttc aaatgatttt
     4981 cagcgttatg tcacaaagtt gattgctctt tatagaattc gtcaggaaag atcttttgaa
     5041 aaattggata tttaccagta cggcaaggaa atggcaagtc tagtggaagg cctccgaaaa
     5101 gctcaaagct tatctgttga catggaccac attgaagctt tagatcaagc gctagccatt
     5161 cataacaaat acgatatcgt ccttaatggt tctcacctga ttaaggattt tgggatgaaa
     5221 ccaggtcctc agctagggct tatgcttgag aaagttgaat tagcgattgt agagggacgc
     5281 ctagataatg atttcactac aattgaagca tttgttagag aggaattagc aacatgagcc
     5341 attttttggt gaagaaattg acaaaaacgg tgggagataa aacagtcttt caggatattt
     5401 cctttattat tcatgacttt gaccgtattg ggattattgg ggttaatgga acaggaaaaa
     5461 caactctttt agatgtcttg tcgggaaggc ttggttttga cggagaccat tcaccatttt
     5521 ctaaagccaa tgattacaaa atcgcttact taacacaaga tcctgaattt aacgatgcat
     5581 cctctgtttt agatacggta ttgtcatctg atgttaaggc gattcagctg attcgtcagt
     5641 atgaactatt gatggcgaat tatactgaag ataaacaaga gaccttagag tccctcatgt
     5701 ctgaaatgga tcgcttagat gcttggtcta ttgaaagtga tgtcaaaaca gtcctatcaa
     5761 aattaggcat cacggatttg gaacaaaaag tgggagacct atcaggtggt atgagaagac
     5821 gtgtccagtt agctcaagta ttgctaggag ctgctgactt actcttgttg gatgagccga
     5881 ccaaccatct cgatattgac accatcgctt ggttaacaac ctatctcaag acagctaaaa
     5941 aaaccgtcct ttttattacc catgaccgtt atttccttga tcatgtggct acccgtattt
     6001 ttgaattgga taaagcggga ctgacagaat atcaaggcaa ttaccaagac tatgtgcgct
     6061 taaaagcaga acaagacgaa cgagatgcta ctaatttaca caagaagaag caactctata
     6121 aacaagaatt agcttggatg aggacgcagc cacaggcgcg tgcaaccaaa cagcaggcta
     6181 gaatcaatcg tttcactgac ttgaaaaaag aagttcacca agacagttct gcagataaat
     6241 tggagatggc tttcgaaacg agccgaattg ggaagaaggt gattcacttt gaagaccttt
     6301 cttttgctta tggcgaccga cagttgatta aggattttaa cttgattatt caaaataaag
     6361 atcgtattgg aattgttgga gataacggcg tcggaaaatc taccctgtta aatatcatca
     6421 acggtgatct caaaccaact tctgggaagc ttgatattgg agatactatt cgtgtaggtt
     6481 atttctctca gcagctcaaa gatatggatg agaccaaacg ggtcattaat taccttcaag
     6541 aagtggctga tgaggttaaa acaagcgtgg gaacaacgag tatcagtgag cttttagagc
     6601 aatttctttt tccgagatca agtcatggca cgctgattgc taaattatct ggtggggaga
     6661 aaaaacggct ctacttgcta aaactgctca ttgaaaagcc aaatgttctt ctccttgatg
     6721 agccaacaaa tgatttagac attgccacct tgacggtctt agaaaacttt ttagctaact
     6781 ttgcaggacc agtcattacg gttagtcacg atcgttattt cctagacaaa gtagccacta
     6841 agattttagc ctttgaagaa ggcgatattc gtatttttta tgggagttac agtgattacc
     6901 ttgatgaaaa agcttttgaa aaagaaacag ttgaggctga cttagctaaa gcaatagtca
     6961 ctgaagaagt gccacttcct ccgaaagagg agaaaaagcg catgtcctac cttgaaaaac
     7021 aagaatgggc tcagatagaa gataaaatag caactattga ggctaatatt gaagaaattg
     7081 aaaaccaaat gttaactgta gttagtgatt atggccagtt agctcaatta caaaaggaac
     7141 tcgatcagcg caataatgat ttattattgg cgtatgaacg gtttgagtat ttgagtggac
     7201 tagacatata agtatactat ggtaatgtta tgtttataat aaacaagtga taatagaaaa
     7261 gaagtgctc
//
LOCUS       DATWEK010000056         7140 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.056, whole genome shotgun sequence.
ACCESSION   DATWEK010000056 DATWEK010000000
VERSION     DATWEK010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7140
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.056"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            12..587
                     /locus_tag="VCR92_001692"
     CDS             12..587
                     /locus_tag="VCR92_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEP4268740.1"
                     /translation="MKKVINTILLAACFLFFLGNFTTNVLAEGINDKMENGTESDISF
                     QNGELLKNYLILEGERVYFDYDRATQDKVSDDVLEMGMLVEAISKDYSEKTFTPDKYF
                     KASWPVHGNYCGPGHNGNNFTLPVVDVLDQGCQNHDSCYKWGAGIGANCECNRQLVNY
                     IKVYRRWMPANVLGVADAIRVYFETVGSIGC"
     gene            933..1115
                     /locus_tag="VCR92_001693"
     CDS             933..1115
                     /locus_tag="VCR92_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEP4268741.1"
                     /translation="MLTYDEFKQAIDNGYIVGDTVAIVRKNGQIFDYVLPGEKVRPSE
                     VVAEEIVEEVVVELDK"
     gene            1360..2100
                     /locus_tag="VCR92_001694"
     CDS             1360..2100
                     /locus_tag="VCR92_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEP4268742.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLF
                     QKEPYDIVLTDINMPKLNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKADVEDMLGKLQQKLDLSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLT
                     LKSLAQQLGFSPNYLSVLIKKDLGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVG
                     FEDMNYFSQRFKQLVGVTPSQYKKGGQA"
     gene            2097..3830
                     /locus_tag="VCR92_001695"
     CDS             2097..3830
                     /locus_tag="VCR92_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP4268743.1"
                     /translation="MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERD
                     TRQSIRQSSQFIDAYIKPLKETTSVLAKNTEIQAFASQIHQENDKQVLQLMKMVLATN
                     SDLQAAVLVTKDGRTVSTNSQLTMKTSSDMMAEPWYKAAIDRQAMPVLTPARQLSLSS
                     KKEWVVSVTQEVVDRAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVY
                     HPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRV
                     QRQIFWSFLGTGLLACLICGFATVLALRRWIRPIQQLQQVILAIQKGDRQLRAQETGS
                     PELTNLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYE
                     VQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLVLTVWDNGK
                     GIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLTLPKMH
                     ELMADDTQENE"
     gene            3903..4982
                     /locus_tag="VCR92_001696"
     CDS             3903..4982
                     /locus_tag="VCR92_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEP4268744.1"
                     /translation="MSLASDYFSRQTPIVEKLMAYGFEKRNNGYFYNERFMEEEFEAQ
                     LRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEVTP
                     FQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVEGKWYAMIFSLLADKLDQIPER
                     LVGQTCEVMTVKVNPKAFPQLLQQEGIYPAYHMSKKNWISIILDDKVTDDKLWTLVTQ
                     SRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYI
                     TAPVKSIRYVCQVLETNIPNEGYRKNPNIDKLMRLRKRQQYKDGLLSFDLMKKHGVAA
                     VRGPRRLSPQLIAFLKEKEYFKENN"
     gene            4996..5712
                     /locus_tag="VCR92_001697"
     CDS             4996..5712
                     /locus_tag="VCR92_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEP4268745.1"
                     /translation="MVEFVADQSFWELFPDAKLGVVLLKDVQNQAESPEDVKQLLADS
                     HELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPL
                     VDIYNAASLRFGLPVGAEDSDSFIGDLRLTITDGGDDFYLIGDADNNPTLPNELCYKD
                     DIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALDFIEGSAKMYLHA
                     ITSVHVLDKDNPHVPLFTEN"
     gene            complement(5878..6351)
                     /locus_tag="VCR92_001698"
     CDS             complement(5878..6351)
                     /locus_tag="VCR92_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEP4268746.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSR
                     DMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGL
                     AQSFGSILDAMQIPEIVATICGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK"
     gene            6493..>7140
                     /locus_tag="VCR92_001699"
     CDS             6493..>7140
                     /locus_tag="VCR92_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEP4268747.1"
                     /translation="MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFF
                     EGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYL"
BASE COUNT         2181 a         1251 c         1572 g         2136 t
ORIGIN      
        1 ggagaaaatt tatgaaaaaa gtaataaata ctattctatt agctgcttgt tttttattct
       61 ttttaggtaa ttttactaca aatgtattag ctgaagggat aaatgataaa atggaaaatg
      121 gcactgaaag tgatattagc ttccaaaatg gtgaactcct aaaaaattat cttatcctag
      181 aaggtgaacg agtatacttt gattatgata gagcaactca agataaagta tcagatgatg
      241 ttctagagat gggaatgtta gttgaagcta taagtaagga ttattctgag aagacattca
      301 ccccagataa gtattttaaa gctagttggc ctgtccacgg taactattgt ggaccaggtc
      361 ataatgggaa taactttacg ttgccagtag tagatgtttt ggatcaaggt tgccaaaacc
      421 acgatagttg ctataagtgg ggtgccggta ttggtgctaa ttgtgaatgt aaccgtcagc
      481 tagttaatta cataaaagtt tatagacgat ggatgccagc gaatgtcctt ggcgtagccg
      541 atgctattag agtatatttt gagacagtag gttctatagg atgttaaatt tcaaaaaaaa
      601 cgttagtgat tattcgaagt actatatttt gagtatagtg ttattatgga taggaatgtt
      661 ctttgttcct tgggataaga ctctattcgg tgtttcgatt tatctgtttg ttatgcaaaa
      721 gttatttata gtgtttggtt tgacggctat cttcatggcc tttgtgtcta aaaaaataaa
      781 tctatttatt tggggaatat tatttatttt cgcattttgg attaatatgt ttttgttatt
      841 ttccgtatta ccaattttgg gaaattagtt taacaaaaaa gaagaggggg gtctccctct
      901 tcttttacga ataaatagat aaggaggtac ttatgctaac atacgacgag tttaagcaag
      961 cgattgacaa tggatatatc gtaggagaca cagtagcgat tgtgcgtaaa aacggacaga
     1021 tttttgatta tgtgttgcct ggcgaaaaag tcagaccgtc ggaggttgtg gctgaggaaa
     1081 tagtggaaga ggtggtggtg gaattagaca aataaaaaag acttttccaa gtcccgaaat
     1141 cagatgctcc ccagcgcaaa attactacgt tatttactac gttgttttta aaatcagtgt
     1201 aattgaccag ataatgtaag gttgtaaaat gttgatttat caagtgatta ggcaatgata
     1261 gcaaatgata ccatattaat gttcttttct gatataatag aagaaagact agtatgagag
     1321 ggccatgcaa ggccctttat aaagataagg agacaccgtg tgtactcatt gttaattgta
     1381 gaagacgaat accttgtgcg ccagggtatt cgttctttgg ttgattttag ccagttcaag
     1441 attgataggg tcaacgaagc agaaaatggc cagttggctt gggacttgtt tcagaaagag
     1501 ccttatgata ttgttttgac ggatatcaat atgcccaaat taaatgggat tcaactagca
     1561 gaactcatta aacaggaatc cccccaaact catctggtat ttttgacggg ctacgatgat
     1621 tttaactatg ccttatctgc tttgaagtta ggggcagatg attacttgct caaacccttt
     1681 tccaaggccg atgtggaaga tatgttagga aagctccagc aaaaattaga cctttccaag
     1741 aaaacagaaa ccatccagga attggttgag cagcctcaaa aagaagtatc agcaatagca
     1801 atggctattc atgagcgatt ggcagattct gatttgaccc taaaaagctt ggctcagcag
     1861 cttggtttta gccctaatta ccttagcgtc ttgattaaaa aagatttagg gatgcccttt
     1921 caagattatc tggtacaaga acggttgaaa aaagccaagc ttctcttgtt aaccagtaat
     1981 cttaaaatct atgaaattgc agagcaggtc ggttttgagg acatgaatta tttttctcag
     2041 cgctttaagc aactggtagg cgttacccca agtcagtata aaaaaggagg ccaggcatga
     2101 agcgttatcc cctactggtc cagttgattt cgtatgtttt tgtgatcgta attgccctca
     2161 ttaccacgct tggtttgctt tattaccaga cgagttctcg taatatcagg caactaattg
     2221 aacgtgatac ccggcagagc attcggcaaa gttcccaatt tattgacgct tacatcaagc
     2281 ctcttaaaga aacaacttcg gtgctggcga aaaatacgga aattcaagcc tttgctagtc
     2341 aaattcatca agaaaatgac aaacaggttc ttcagctcat gaagatggtt cttgcgacca
     2401 attccgattt acaagcagct gttctggtga ctaaggatgg tcgaacggtg tctaccaatt
     2461 ctcagttgac catgaaaacc tctagtgaca tgatggcaga accctggtat aaagcagcca
     2521 tagaccgtca ggccatgcca gtcttgaccc cagctcggca attatccctt tcttctaaaa
     2581 aagaatgggt agtttctgtg acccaagagg tagtagatag ggctgggcat aatttaggtg
     2641 tgctaagact tgatattgca tacccgacca ttaaagcgtc tttagatcag cttcagctag
     2701 gccgccaagg ctttgccttt attgtgaatg ataagcatga atttgtttac catcccaaaa
     2761 agagtgttta cagttcttct aaggagatgg ctgcgatgaa gccttattta gcgattcaga
     2821 atggttacac taaggacaag acatcttttg tttaccaaaa actcattcct aacagtcaat
     2881 ggactttagt gggagtggcg tcactggatc agttgcaccg ggtgcagcgc caaatttttt
     2941 ggtcctttct tggaacaggg cttctagcct gtctgatttg tggctttgca actgtcttag
     3001 ccttacgcag atggattcgt cccattcaac aattgcagca agttattctt gctattcaaa
     3061 aaggagatcg tcagttacgt gcccaagaaa cgggttctcc agaattgaca aaccttgccc
     3121 aacagtttaa tgcgctctta gatcaaattg atagcttgat ggttgccgtt gcggataagg
     3181 aaaaggcgat tgggcagtat aggttacaag ccttggctag tcagattaac ccgcattttc
     3241 tctataacac cttggacact attatttgga tggcagaatt taatgacagc aagcgcgtgg
     3301 tagaagtgac caagtctcta gctaagtatt ttcgtttggc ccttaatcag gggaacgaat
     3361 acattcgttt ggcagatgaa ctggatcacg ttagccaata cctctttatt caaaaacagc
     3421 gctatggaga caagctaagt tatgaagtgc aaggcttaga tgtctacgca gactttgtta
     3481 ttcctaagct tatcttacag cccttagtag aaaatgctat ctaccatggc atcaaagaag
     3541 tcgatcgcaa aggcatgatc aaggttacgg tatctgatac agctcagcat ctggtgttga
     3601 ctgtttggga taatggtaaa ggcattgaag actcttcact gaccaatagt cagagcttgt
     3661 tggctagggg aggtgtgggc cttaaaaatg ttgaccagcg gttaaaactt cactatggtg
     3721 aaggctacca catgaccatt catagccagt cagaccagtt cactgaaata caattaaccc
     3781 ttcctaaaat gcatgaatta atggcagacg acacacagga aaatgagtaa ggttacagga
     3841 agtgcatgtc agccatttcc ctaagttagg gtattggaga taagaacctt agaaaggata
     3901 tcatgagttt agcatctgac tattttagcc gacagacccc catagttgaa aagctaatgg
     3961 cttacggttt tgaaaaacga aataatggtt acttctataa cgaacggttt atggaagaag
     4021 aatttgaggc gcagcttagg attgatgagg ctggcaatat ctgggatcgg gttattgatt
     4081 gtgacttgga ggaggattat ttgcctttac aacaagcagc ctggcaagga acctatactg
     4141 ggcaggttag agcagcctat ttggaactct tggagcgctt atcagtagcc tgttttgaag
     4201 tcactccttt tcagtcaatg caagctaata gacttgctaa gcatatcacc aaagaatggt
     4261 ctgacccaat ggactatcct tttgaaaagc acccagacct tgcaacctat cgggtagagg
     4321 gcaaatggta tgctatgatt ttttctctct tggctgataa attagaccag ataccagaga
     4381 gattagtagg acagacatgt gaagtgatga ctgtcaaagt taatcccaag gctttccctc
     4441 agttactgca gcaagaaggc atttacccag cgtatcacat gtcaaagaaa aactggatta
     4501 gtattatttt ggatgataag gtaacagatg ataagctttg gacgttagta actcaaagtc
     4561 gtcaactagt caacccaaac ggtctttcta atcctaatgg tcctgattat tgggttattc
     4621 cagctaattt gaaatactat gatattgatg cagaatttgc agccaatgat gtgattttat
     4681 ggacccaaaa agctggtatt gccgtgggag actatgtgct gatttatata acagccccag
     4741 tcaaatccat tcgctatgtc tgccaagttc tagaaaccaa tatacctaac gaaggctatc
     4801 gtaaaaatcc taacattgac aaactcatgc gtctccgaaa acgccaacag tacaaggatg
     4861 gtctcttgtc ttttgacctt atgaaaaaac atggcgtagc tgcagtgaga gggccaagac
     4921 gattaagccc tcaattaatt gcatttttaa aggaaaaaga gtattttaaa gagaacaact
     4981 aaaggagaat aagagatggt tgaatttgta gcagatcaaa gtttttggga actttttcca
     5041 gatgccaaac taggtgtcgt cttattaaag gatgttcaga atcaagcaga gtcaccagaa
     5101 gatgtcaaac agctcttagc agacagccat gagttagcaa aagcttattt aacagcagac
     5161 aattttagtg ataatcaggt ggttcaagtc taccgcaagg cctatcaaca ctttaaaacc
     5221 aaaaaaggag ctcgctctag cattgaagcc cttctcaagc gggtgtcaaa tggtcaaagc
     5281 attccgtcga tcaatccgct agtggatatt tataatgcag ctagtctacg ttttggttta
     5341 cctgttggag ccgaagatag tgacagtttt atcggagatt tgcgtctgac gataacagac
     5401 ggtggtgacg acttttactt gattggggat gctgacaata acccaacctt gccaaatgag
     5461 ctgtgttata aagatgatat tggagcggtt tgtcgttgcc ttaactggcg agatggcgaa
     5521 cgcaccatgg tgacagaaca caccaaaaat gcatttttga ttatcgaagc tcttgatcaa
     5581 gaaggtcaaa atagattgca agaagctctt gacttcattg aaggcagcgc aaaaatgtac
     5641 cttcatgcaa tcacctctgt gcatgtgttg gataaagaca atccacacgt gccacttttt
     5701 acggaaaact agattagtag gatgaactgt gtaaaataga aggttaacaa aaaagcgagt
     5761 aaacgaatgt cctgtcattt aggtttttgt ttactcgctt tttgatgaga ttttactgct
     5821 gtcctagcaa aaggtgagga tgaggtcgta tatcacatag aggttttctg ttaagcctta
     5881 tttgttacta aagaagaatg gtggtgtgta atgactaagg gtctcgtaac aagccttggc
     5941 ttgctcattg tcttcacaga caatcaagca agtatcatca ccacagatcg ttgctacaat
     6001 ttctggaatt tgcatggcat ctaaaatgga gccaaaggat tgggctagtc caggtaacgt
     6061 ttttaaaata atttgatgtt gaactatctt taacatgacc aaagcgtctt ccatgtaaaa
     6121 acgaagacga tgttcccagc gggtttgtga aatggctaac gcttcatagt gtgtgtcgtt
     6181 tccggaagtt actttgacca ggttcaattc cttcatgtca cgtgataggg tagcctgagt
     6241 gatcgtgatg ccattttttt gcaaccgttc ttgtaattct tgctgtgtat gtatagttgt
     6301 ctcagagatg agggaacgta tgagttggtg acgcgtctct ttcttattca ttgttataat
     6361 cttcctttaa cgtaattgat aacaatccga gtatagcaaa aagaggagaa ggtgtaaagt
     6421 ttttgatgaa ccgcttacaa aatggctttt ttatggtaaa ataaagatga tgtttagaaa
     6481 aaggagattt gtgtgattcg aagagaagat tatcaatacc ttagaaaact aaacgatttt
     6541 cgctactttt ctattgaaca atttgacaaa attgtagggc agatggaatt ccgaaaagct
     6601 aaaaaggacc atatcctttt ttttgaggga gataaaagag ataagctttt tctagtgacc
     6661 tctggttatt tcaaggtgga gcagtccgat caatcaggaa ccttcatgta tacggatttc
     6721 atcagacacg gtaccatttt tccttacggt ggcctcttta cagatgatta ttaccatttt
     6781 tcagtggtag ccatgacaga cgtgacttat ttttactttc cagtcgattt atttgaagat
     6841 tattcgcttg aaaatcgtct acaaatgaaa cacttatata gtaagatgtc taaactgctc
     6901 gagttacatg agttgagggt tcgaaatttg attacatcaa gtgctagttc tcgtgtgatt
     6961 cagtctctgg cgattttgct ggttgaaatg ggtaaagaca gtgatacctt accttttcaa
     7021 ttaacaacaa cagatattgc tcaaataagt gggacgacaa gagaaactgt tagccatgtg
     7081 cttagggatt tgaagaagca agaattgatt accataaaag gtaagtattt gacttatcta
//
LOCUS       DATWEK010000057         7114 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.057, whole genome shotgun sequence.
ACCESSION   DATWEK010000057 DATWEK010000000
VERSION     DATWEK010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7114
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.057"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            231..1004
                     /gene="cfa"
                     /locus_tag="VCR92_001700"
     CDS             231..1004
                     /gene="cfa"
                     /locus_tag="VCR92_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_149017463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAMP factor pore-forming toxin Cfa"
                     /protein_id="HEP4268748.1"
                     /translation="MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTILMNNNQA
                     NLQRDALVQKLDEGHQQLEAIKHEAKGTDIEATVNKAIDAVDHMKSSIRFNTETIYDF
                     SSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKA
                     QVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKSFDVYNR
                     LNKAITHAVGVQLNPTTTVQQVDDEVIAVQNALETALKS"
     gene            complement(1374..2609)
                     /locus_tag="VCR92_001701"
     CDS             complement(1374..2609)
                     /locus_tag="VCR92_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HEP4268749.1"
                     /translation="MTQDPIANLKLARKGPIVSIIVYLLLSAAKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLI
                     HTIKRIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLAD
                     AVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLK
                     KYEKAILEIPKIVAVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKVEQLLSDQ
                     FSIYDIDIHVEPAMILEEEIFDNVAKKLYRYEKLILSKVPDYDHYIAKSFQLVDANGQ
                     TVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQHTSIWRRHESWSLLFHQ
                     ITPIAKRQLHHTHYRIVKM"
     gene            complement(2729..4051)
                     /locus_tag="VCR92_001702"
     CDS             complement(2729..4051)
                     /locus_tag="VCR92_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEP4268750.1"
                     /translation="MIALVKLIDNLVWGPPLLILLVGTGIYLTSRLGLIQILKLPRAF
                     KLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIG
                     TFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYI
                     LSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTNESVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLT
                     QSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFILM
                     VGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK"
     regulatory      complement(4179..4265)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            4580..6898
                     /gene="pcrA"
                     /locus_tag="VCR92_001703"
     CDS             4580..6898
                     /gene="pcrA"
                     /locus_tag="VCR92_001703"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEP4268751.1"
                     /translation="MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKFVNPWNILAITFTNKAAREMKERALSLNPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQA
                     ADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVL
                     LEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVAST
                     ISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIA
                     YLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKG
                     KAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIE
                     EFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLF
                     GKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQAR
                     KAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLE
                     VSGSGKTMELKIKFPEVGLKKLLASVAPIEKK"
BASE COUNT         2407 a         1305 c         1377 g         2025 t
ORIGIN      
        1 aaatgacaag aaaagttatt ttaggtcaat taacgtccgt ttaaaagtaa tactagacat
       61 ttaatgacat taaaaaatga ttatttttgc gaaatcctct tattttctgg aaattaaaga
      121 aatattgacc ttagtaaaaa caagtagtat gataacgtta taagcgctta taaattaatt
      181 taacttcact taactattta aataggttta ttatattcag gaggaataat atgaaaccca
      241 aacaccttct ctgtctttca acagttgttg ctggattagc tttattttca actatgacgc
      301 actcagtttt agctgatgat gcttcaaatc ccgatactat tttaatgaat aacaaccaag
      361 cgaatcttca aagagacgct ctagtgcaaa agcttgatga gggacatcaa caattagaag
      421 ctattaaaca tgaagctaaa ggtactgata ttgaggctac tgttaacaaa gctatcgatg
      481 ctgttgatca catgaagagt tctatacgct tcaatactga aacgatctat gattttagtt
      541 caattggggc aagagtagaa gcattatcag atgctatcaa agcaatcgta ttttccacaa
      601 cccaattaac tcacaaagta gaaaaagcgc atactgatat ggggtttgct attactaaat
      661 tagtcattcg tattatagat ccatttgcat ctgttgacgc tatcaaagct caagtacaag
      721 aaattaaagc acttgaggaa aaagttatca attatcctga tttacagcca acagaccgtg
      781 ctactatcta tactaaagct aaactaaata aagctatttg gaacactcgt ttagaaagag
      841 ataaaaaggt tttagggatc aaatcatttg acgtttataa tagacttaac aaagctatca
      901 cacatgcggt tggtgtccaa ctaaatccga caaccactgt tcaacaagtt gacgatgaag
      961 ttattgctgt gcaaaatgct ttggaaacag ctcttaagtc atagagtgta taagtaatgt
     1021 gttgtatagg tagatgatta tattaggata tagaataggt aaagatttta aatatcttac
     1081 cattgtagag tttgaggtga tgttctcata aacaatgagt cacctgtagc cctttttgcc
     1141 tttaacatga tgtaccaatt taaggtattg ttcaaccgtc actattgaat cttgtttaac
     1201 ctcctaaact aataagattc aatatgaaaa cgtgtattct taaaaaaatc cctatgatct
     1261 gtttaaaaac aaattgtagg gattttttta actatttaac ttattatttt gggactagga
     1321 atcgctttag gaatatcatg aagtatagtt atgttataag ataagtaatg tttttacatt
     1381 tttacaatac gatagtgtgt gtgatgtaat tgtctcttag cgataggggt aatttggtgg
     1441 aagagtaagg accaagattc atgacgcctc caaatactgg tatgttgatt gccatttaat
     1501 tggtaagtta ccaacatcgt tttttgacta atggattcaa tctgaaaatg gttgaagtta
     1561 cttggataat aaatttcttg gttcaaaaat tgttcatagt taactgtttg gccattcgca
     1621 tcaaccagtt ggaaagactt agcaatgtag tggtcatagt caggaacctt actcaaaatt
     1681 aatttttcgt agcggtagag ctttttggcg acattatcaa aaatctcttc ttcgagaatc
     1741 atggcaggtt caacgtgaat atcaatgtca taaatagaaa attggtcact caataactgc
     1801 tccactttct ctgtaataga gtgactttca tagactgaaa gatcaggatt catttcaagt
     1861 acaatatcaa gatagacatt gctaccatag gtcctagctc gttgagactt aacggcgaca
     1921 attttaggga tttctaaaat ggctttttcg tattttttca aatgacggct atcaaatcca
     1981 tcagataaac taaacgaact ttccataaag atatcaaaag ctgttttaag aataaagaac
     2041 gtaatgatca tagcagctat atgatcgata actggtaaat gcaaagaagc tgctataata
     2101 gcaattgatg ttccgataga agtaacagca tcagctagat tatccttaga agcagcgact
     2161 aaggcactgg attttacacg tttggaaaga cgtttgttaa agacatagac ccctaacata
     2221 acaaaagctg aaacgatacc gacaatagcc ccaagagggt caatatcaac ttgctgacca
     2281 ctaaagatac gtttaattgt gtgaatcagt acttggaaac ctacaagaaa cataataaaa
     2341 gaagtgacaa ggctggataa atcttcaatt ttccaatgac caaatttatg attggcatcg
     2401 gctggttggc tagctaagtg aagaccaata agcagggcta catttcccac aatatccgat
     2461 aaattgttaa atccatcagc aataagggaa cttgcattta acaaataacc agctaataat
     2521 ttggcagcac taagcaacaa gtagacaata atactaacga ttgggccctt tctggctagt
     2581 tttaaatttg caatcggatc ctgtgtcata ataactcctt tgatttcaac tttatattat
     2641 accataaaaa ggggcttaag aaaaaagcct agcttcttga acttggcaga agaagactag
     2701 gtataactgg gtagtactaa cgtcatgttt acttaataaa gtaatgcttg gtttctaaaa
     2761 taacaactgg cgagagagct aggagggcaa tcaggttagg aagtgccatt aaaccattga
     2821 caatatcagc caaaacccaa atcagttcta acttaaggaa gcctcctagg cctaccatta
     2881 agataaagac aatacggaag taggtgagat gtgtaatgcc aaagaggaat tcaaagcagc
     2941 gttctccata ataactccat cctaaaatcg ttgtaaaggc gaagagaact agggaaaagg
     3001 ttaggccaaa agtccctaaa tttccaaaca cagtggcaaa ggcagattgg gtcagaggag
     3061 ccccttcgag ctgcccagtc cattggcctg ttactaaaat agataggccg gttagggtac
     3121 agataataat cgtatcaata aaagttcctg tcatggagat caggccctgc tccacggatt
     3181 cattggtttt agctgctgct gcagcaatag gtgcagatcc tagtccagac tcattggaga
     3241 agacaccgcg tgcaattcct ttttgaatgg catccttcat gagacttcca gcaaagcctc
     3301 caatagcagc tgtcggagtg aaggctgatt gaaagactaa acgaataaca ggaagtagct
     3361 gctggtagtg actaaaaata actgctaaac tagatagaat ataaaaaata gccataaaag
     3421 gaacgacttt ttcagccact ttggaaatgg aatgaatgcc accaaaaata atggcagcca
     3481 caaagatagc taaaacaata ctgaccattt gtggggataa gccaaagcta tgacctaaag
     3541 acgaggtgat cgagttcact tgagcaaagg ttcctattcc aaatagggca actaggatcc
     3601 ctgaacccgc aaaaagaatg gctaagggtt tccattttgt ccccatgcca ttaacaatat
     3661 agtacatagg accaccagaa atatgaccgt tggcatcctt tgtacggtat ttaatcgcta
     3721 gtaccccttc agcgtactta gtggccattc caaaaaaagc ggcaacccac atccaaaaga
     3781 gcgctccagg accaccagac ttgatagcag tggcaacccc aacaatgtta ccagttccga
     3841 cagtagcggc aagggcagtt gcaagagcag caaaggatga aatatctcca tgtccttcgt
     3901 catctgaaaa aatgagttta aaggctcttg gtagttttaa gatttgaatt aatcctaaac
     3961 gactggtaag gtaaatcccc gtcccaacca ataaaattaa gaggggcggt ccccaaacaa
     4021 ggttatcaat taatttaacg agtgctatca tctttctctc ctaaaagtca tcgaagacgc
     4081 caaaagaaaa aagctatctc tttctttgag acaacttctg aagcaatgat aaaacagcaa
     4141 acacaaaaaa gactaagact gttcttaatg gtgtttgtat tttaccttct gtccttttgc
     4201 ctgagagatt gagcagtatg ccttgcccct tcggcgccta ataaggtctc tccagaagtc
     4261 cgtccatcaa acagtcccgt tcaaaaactg aacacctgag agtataactc cttcggcgaa
     4321 aaaaattctt ctcctgcatg acatcattcg gtttattaaa ttaggactat catacctcaa
     4381 aaaacgaatg aagtcaacca aaatagcaaa aaaataagga atgctttaag aaatcgctat
     4441 tatttttaaa tatctgatcc taaactagaa aaaaggaatc tctttacttt tggggtcttc
     4501 tttgctattt ttcttggaaa catgatataa ttttaaggtt gataaaagag atgtcactga
     4561 acgagattaa ggagaaagca tgaatccttt attaaatgga atgaatgatc ggcaggcaca
     4621 agctgttcaa acaactgaag gccccttatt gattatggcg ggggctggtt ctggtaaaac
     4681 aagggtactg acccatcgta ttgcctattt aattgatgaa aaatttgtca atccttggaa
     4741 tattttagct attaccttta ctaataaggc tgcgcgtgaa atgaaagaaa gagccttgtc
     4801 cttaaatcca gctactaaag ataccttaat tgctaccttt cactccatgt gtgtacggat
     4861 tctgcgtcgt gaggctgatc acattggtta caaccgaaac ttcacaatcg tggatccagg
     4921 tgagcaacga acgttgatga agcgcatttt aaaacaatta aatatagacc ctaaaaagtg
     4981 gaatgaacgt tctattttag gaactatttc aaacgctaaa aatgatttgc ttgatgaaaa
     5041 gggatacgag gcacaggctg ctgatatgta tagtcaaatc gtagcgaggt gttacaaagc
     5101 ttatcaggaa gaattacgac gtagcgaagc acttgacttt gatgatttaa tcatgatgac
     5161 gctacgcctg tttgacgcta atcctgacgt gttagcttat taccagcagc gttaccaata
     5221 cattcatgtg gatgagtacc aagataccaa ccatgctcaa tatcagctaa ttaaattgct
     5281 agcttctcgc tttaaaaata tttgcgttgt tggagacgct gatcagtcta tctatggttg
     5341 gcggggagct gacatgcaaa atattcttga ttttgaaaaa gattacccag atgctaaggt
     5401 agtgctttta gaagaaaact atcgctctac caagaaaatt ctgcaagcag ctaacgacgt
     5461 gattaacaat aaccgtaatc gccgtcctaa gaaactttgg acacaaaatg cggatggtga
     5521 acaactggtt tattaccggg caaatgatga gcgagatgag gcagtatttg tggcctcaac
     5581 cattagcaat atgagtcaag agcttggaaa aaacttcaaa gatttcgctg ttttataccg
     5641 taccaatgcc caatctcgga ccattgaaga agcactctta aaatccaata ttccttacac
     5701 catggttgga ggcaccaagt tttacagccg taaagaaatt cgggatttga ttgcctattt
     5761 aaccattgtt gctaaccctg ctgataatat ttcttttgag cggattgtga atgagcctaa
     5821 acgaggtgtt ggtccaggaa cgcttgataa actgcgtcag tttgcctatg agagtgacca
     5881 gtctttatta gaagcagctt caaatctatt gatgtccccc ttgaaaggta aagcagcaca
     5941 agctatcatg gacttggcca atattctcgg tcagctacgt caagacctag atcagatgag
     6001 tatcaccgac ttagcagaag ctttgttaga aaaaacaggt tatttagata gcttacgcct
     6061 gcaaaataca ttggaaagcc aagcccgtat cgaaaatatc gaagaattct tatctgttac
     6121 caaaaatttt gacgagtcaa gtgcctctca agaagaagac gaaaccggtg ttgatcgctt
     6181 gggacgtttt ttaaacgatt tagcactgat tgctgataca gatgattccc aagcagaagc
     6241 tgctgaagta accttaatga ccctacatgc tgccaaaggc ttggagttcc ctgttgtttt
     6301 cttaattggt atggaagaag gtgtcttccc cttatcacgt gcctctgaag atccagatga
     6361 attggaagaa gaaagacgtt tagcttatgt cggaatcaca agagctgaag aagttctctt
     6421 tatgaccaat gccaacacca gaaccctctt tggtaaaagt agttataacc gtccaacacg
     6481 cttcttgaaa gaaatttcag aggaactact ctcttataaa ggattggcaa gaccagcaca
     6541 atcttcattt ggtgtgcgtt tttctactga aacacacaca cagtttggac aagggatgag
     6601 cctatcagaa gccttacaag ctcgaaaggc ccaggctcaa gtaagacaat cagcacagcc
     6661 aatgcaggca catacgatac catcagcttc aactagctca gttttaccgt ttggttctaa
     6721 tagctctgta gaagaggtca cttggcagat tggcgatatc gctcaccata aaaaatgggg
     6781 agacgggact gtgcttgagg tttcaggctc cggaaaaacg atggaattga aaatcaaatt
     6841 tccagaagtt ggtctaaaga aattactagc aagtgttgct cctattgaga aaaaataaga
     6901 aaaaaatgag cttcctacta tataagtgag taggaagctc atttttttag atttctgtat
     6961 catataaaag ttaaaaaatt ttaagtttta ggagcatatc agttgcattt taaatttaaa
     7021 ggtgtataat aacaatataa attaaataac gagtggtcac tttataaaat attatcaaaa
     7081 taacatttta taggattttg aaatatcggt attc
//
LOCUS       DATWEK010000058         7078 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.058, whole genome shotgun sequence.
ACCESSION   DATWEK010000058 DATWEK010000000
VERSION     DATWEK010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7078
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.058"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(159..1418)
                     /locus_tag="VCR92_001704"
     CDS             complement(159..1418)
                     /locus_tag="VCR92_001704"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEP4268752.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGV
                     PAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYM
                     DTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQ
                     GVQKLHGTRHQVIPDRIEAGTYIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMT
                     VEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADGRGTIIDTIYEKRIN
                     HVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITN
                     IEFILRGYASIIAKLTALGADIQLIED"
     gene            complement(1592..2788)
                     /locus_tag="VCR92_001705"
     CDS             complement(1592..2788)
                     /locus_tag="VCR92_001705"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEP4268753.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAE
                     TCVYTGSVHVFGEISTKAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSG
                     DIAQGVNEALESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLA
                     ELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKV
                     IKAVIPADYLDDDTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPE
                     AVLEAAVRQVFDLRPAGIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKVDALVE
                     AVKTVL"
     gene            complement(3324..5702)
                     /locus_tag="VCR92_001706"
     CDS             complement(3324..5702)
                     /locus_tag="VCR92_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEP4268754.1"
                     /translation="MKTKKVIILVGLLLSSQLTLISCQSRGNGTYPIKTKQSRKGMTS
                     NKIKPIKKSKKTNKTHKGMAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIF
                     YADLKGSPFEYLIPKGASLAKPAVAQQAASQGTSKVADPHHHYEFNPADIVAEDALGY
                     TVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSPVSTATANGIPGLHFPTSDGFQ
                     FNGQGIVGVTKDSILVDHDGHLHPISFADLRQGGWAYVADQYDPAKKAEKPAETPHTP
                     ELSEREKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIG
                     KDIPEPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTSFPSNEKDPNKM
                     KEWLATVIKLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKRLLMT
                     KTGVTDYRFLDNMPQLEGIDISQNNLKDISFLSKYKNLTLVAAADNGIEDIRPLGQLP
                     NLKFLVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLSRNADVD
                     LATLQAPNLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEA
                     EGNQIKSLVLKDKQGSLTFLDVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPN
                     KTVTNIDISHNNIPLADLKLNEQHIPEAIAKNFPAVYEGSMVGNGTAEEKAAMATKAK
                     ESAQEASESHDYNHNHAYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD"
     gene            5906..6847
                     /locus_tag="VCR92_001707"
     CDS             5906..6847
                     /locus_tag="VCR92_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEP4268755.1"
                     /translation="MKTSEKIYQLLSQTDDFVSGEYLADQLSISRTSVWKSIKSLENQ
                     GIQIDSLKHKGYRMVQGDILLPKTISQGLGMPVTYTPHSQSTQLDAKQGIEAHNSAPR
                     LYLAPSQEAAKGRLDRQFFSASTGGIYMSMYLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTEIKWVNDIYLGNHKVAGILTEAITSVETGLITDVIIGVGLNFFVTDFPEAIA
                     QKAGSLFTEKPTITRNDLIIDIWKLFLSIPVKDHVKVYKEKSLVLNKQVTFTENSQEK
                     RAIAIDLTDQGHLIVQFENGDFQTLRSGEISLSSWEN"
     gene            complement(6822..7025)
                     /locus_tag="VCR92_001708"
     CDS             complement(6822..7025)
                     /locus_tag="VCR92_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEP4268756.1"
                     /translation="MTIRQFLFMAFVCAFETYFFNDLLLSGNYLFALFWGLLLFRDLR
                     RVHTINQLTKTILKTANSPKKKD"
BASE COUNT         2103 a         1500 c         1258 g         2217 t
ORIGIN      
        1 actcattatt ttagcattaa aattaataat attagttagt gatatcattt ttatattttt
       61 tatgacagtt aaaaagccat aaaatgcaac aaagtatgca cctaagtatt attagcctaa
      121 gcacatgtaa tataaaaaag agaagcgtta gcttctcttt agtcttcgat taattgaata
      181 tctgccccta gtgctgttaa ttttgcaatg atactagcat agccacgtaa gataaattca
      241 atattagtaa tttctgtctt gccttcagct attagaccag cagtcactag agccgctccg
      301 gcacgtaaat cagtggcttt gacctgagct cctgtcaggc gagacggccc ttgataaaca
      361 atctgaccac caataactga gatatctgct cccatgcgca tcaactctgg cacatggtta
      421 atgcgctttt catatatagt gtcaataatc gttccacgac catctgcttt taacaacaag
      481 ggcgttaatg gctgttgcaa atcagtggca aaaccagggt aaggagaggt tttaattgta
      541 atagccttga gggattcttg cttttcaaca aagatagcat cctcttctac cgtcatacgg
      601 acacccattt cttctaactt agcaatgaaa ctctctaaat gctcataaag aacattagtg
      661 atcttaacac cttttccaat agctgccgcc aaagcgatat aagtccctgc ttcaatacga
      721 tcaggaataa cttggtgtct agtaccatgc aatttctgaa caccttgtat cgtaataata
      781 tctgtacctg ctccacgaat atgcgcaccc atgttattca aaagagtagc cacatcaata
      841 atctctggct cacgtgcagc gttttcaata accgttttac cttgagcttt tgttgccgca
      901 accatagtat taattgtagc accgacacta acggtgtcca tatagatatg agcgccatga
      961 attttttgac catttgtcga taaattcata ttttcaccct cataagacac ttcaactccc
     1021 atagcctcga aggccttcaa atgcaagtca attggtcttg gtcctaaatc gcaaccacca
     1081 ggtaagccaa caactgcttg tccaaaacga cctaaaagac taccgtagaa ataataggaa
     1141 gctcgaagac tattaatctt tccgtaaggc atcgggatgt cttgcacccc tctagggtca
     1201 atttctaaag tatcaccatg atagtttact gttgctccca taagctccat gatttcaatc
     1261 agactatcta catcactaat agcaggtaca ccatcaagaa tcacaatatc atcggctaag
     1321 atgattgctg gaataagcgc aacaacactg ttttttgccc ctgaaactgc cacttctcca
     1381 gataaggctt ttccgccatt aataataatt ttacgcatac attcaaaact ttcttatact
     1441 agaattcaac cttttcattt tatcataaat catgaagcct gacaattatt gacgtcttaa
     1501 tttttaatca tcccttttaa aggcttattt aataacaaaa aagcagagta agattttttc
     1561 actcactcta cttttttaat aaagttgtcg tttataatac tgtttttaca gcttctacta
     1621 aagcatcaac cttatttaaa cgctcccatg gcaaatcaat atctgttctc cccatgtgac
     1681 cataggcagc tgtttgtttg taaatcgggc gttttaaatc aagcatttga ataatgcctg
     1741 ctggccgtaa atcaaagact tgacgaacag cagcttctaa aacagcttca ggaaccgttg
     1801 aggttccaaa tgtatccacg cgaacagaca caggctgagc caccccaatc gcataagcta
     1861 gttggacttc agctttcgtc gcaagacctg ctgccacaag gtttttagca atataacgag
     1921 cagcataaga agccgaacgg tccacttttg tcgcatcttt tcctgaaaaa gcaccgccac
     1981 catgacgtga atagcctcca taggtatcca caataatctt acgtccggtc aatccagagt
     2041 ctccttgcgg acctccaata acaaaacgtc ctgttggatt aatgaagaac tttgtgtcat
     2101 catctaaata atctgctgga attacagcct tgatcacttt ttcaatcaca tcctgacgaa
     2161 tttggtcatt agtagcttct ggatcatgct gagtagaaat aacgactgta tccacacgaa
     2221 caggtttatc gtgttcatcg tactcaactg tcacttgaga tttagcatct ggacgtagat
     2281 aactaatctc acctgactta cgtaattccg ccaagcgacg cactaattgg tgagataagg
     2341 aaattggtaa aggcatcaat tctggtgttt cattgatggc aaaaccaaac atgagccctt
     2401 ggtcacccgc tccaatatgg ctaaggtcat cagtatcacc ttctctgctt tcgagagctt
     2461 cattaacccc ctgagcgata tctccagatt gttctacaag tgatggatgt actcccactg
     2521 attctgctga aaagccatat tctgcttctg tataaccaat ttctgcaatg gtgtcgcgga
     2581 ccacacggtt aatatcaatg tatgcttttg ttgagatttc tccaaaaaca tgaacagaac
     2641 ctgtgtaaac acaagtttct gcagccacat gggcttctgg atcttctgct aaaatggcat
     2701 ctaaaatagc atctgaaatt tggtctgcaa tcttatctgg atgcccttca gatacggact
     2761 cagacgtgaa aagtttacgt tctgacataa aaatgtcccc cctaatatgt tgattcttcc
     2821 tttttcagtc acattgacca caaagcaaga agttgcctac ccctttcttc ctagctgatt
     2881 gagcaagtca agtggccaaa accaacttag ctaatcagtt acggttttac tagtaaggca
     2941 actagctagt ccacctagtg gctagcgtcc attaaccaga caaagaatgt ctgacaatag
     3001 cgttgagtta caaagaatcc ggtttccttg ttgagaggat gtcaccacaa aataagcctt
     3061 agacgaagta atttagctaa agagagaacg actgttcccc aaatgaagtc aacaacgtct
     3121 caaaacattt cgttcaacag accgtcttat cgggactcaa taacaatcta ttataacatg
     3181 ttttagccat ttaggtgcca ttcttttcac tcattatcct atttatttca aaaaaacctc
     3241 aaggttattc ttgaggtttt cttgatagtc aacaatggtg tcattaagac gattcagttg
     3301 gatcgggtta ttcttagatt agtttagtca gcatggtttt gctcatcttt agcttcattt
     3361 tcatcctcat gttcatggtc gtgatcatct ttgtctctgt gctcgtgagc atgaccttct
     3421 tcatcttcat aggcatgatt atggttgtag tcatgtgatt ccgatgcttc ttgagcactt
     3481 tctttcgcct tagtagccat agctgctttt tcttcagctg ttccattacc taccatagaa
     3541 ccttcgtaaa ccgctgggaa gtttttcgca atggcttctg gaatatgttg ctcgttcaat
     3601 ttaaggtctg ccaatgggat attgttatga ctaatatcaa tgttagtaac tgtcttattg
     3661 ggtttagata ggttgacatt tgttaattgg tttttagaca cgcttaaaat gtcaagtgct
     3721 gtaaaattat taacaccttc tagagaagtc aactggttgc ctgtcacatc caagaaagta
     3781 agtgaccctt gcttgtcttt aagcacaagc gatttaattt ggttaccttc tgcttctact
     3841 ctgacaatga cgctacttgc ttcaatacct tcaagagatt gcaattgcgc acggttaata
     3901 gataggctag atagattagg attatttttc aagaaatcca aatgagaaac cttggtatca
     3961 ttgaccatta acgtttctaa gttgggtgct tgaagtgttg ctaagtcaac atcagcattt
     4021 cttgataaat caacaaccgt caatgattct ttatgagaaa cagggcttaa atctgtaatc
     4081 tgattattat caatgtgcaa ttcttgcaat tgatgtaacg atgccagtgg gcttaaatca
     4141 gaaatcttat tattactcaa tacgaggaat ttgagatttg gtaattgacc aagcggccta
     4201 atatcttcaa taccattatc agcagccgct actagagtta agtttttata tttgctcaag
     4261 aaactaatat ctttgagatt gttttgtgaa atatcaatgc cttctaactg tggcatatta
     4321 tccaaaaatc tataatcagt cacccctgtt tttgtcatta gtaaccgttt caatttttta
     4381 aattgcaaaa caggtgagat atctttgatt ggtgtaaagc caattcctaa agtttctaag
     4441 ttgggtaaca gtgaaagtcc tttacgttgc aaaggatctt tacggctgcc caagtcaagt
     4501 ttgataaccg ttgctaacca ttctttcatc ttattcggat ctttttcatt tgatgggaat
     4561 gaggttggag catcgtgagt gcgaacgata tccaaaatca cttcttcatc aaaccctaag
     4621 gcacgcaagg tatccattcc aaccttatgt ttttccaatt cacgggcatg ctcaatagca
     4681 tgtggttctg gaatgtcttt tccgatttca atatcagata acatcaatac gtgtgcgtgg
     4741 tcatggtgag ggtattccaa accaagttta ccgtcttgtg tttccacacg tttaatagtt
     4801 gatggatcaa tccccaattt ttctgccaaa taagctaatt tttcttggta ttccttttca
     4861 cgttcagata gctctggtgt gtgaggggtt tctgctggct tttctgcttt tttagcggga
     4921 tcgtattgat ctgccacata tgcccagcca ccctgacgaa ggtccgcaaa agaaatagga
     4981 tgtaagtgac catcgtggtc cactaaaata ctgtcttttg ttaccccaac aataccttga
     5041 ccgttaaatt gaaaaccatc tgaggttggg aaatgcaagc ctggaatacc attagctgta
     5101 gctgttgaaa cagggctact ggtttgtggc aagcgagtag caacctgttt agcttgtgcc
     5161 tgtgtctgac ctgataagct tgacttcaaa atataatgga agtgatcatc gtggcgaacc
     5221 gtgtagccta aagcatcttc agccacaata tccgctgggt taaattcata atggtgatga
     5281 ggatctgcta ctttagaagt cccttgacta gctgcttgct gagcaacagc tggcttagct
     5341 aaacttgctc cttttggaat aaggtattca aatggacttc cctttaaatc ggcataaaaa
     5401 ataaaatgcg aatgaccatc atggtcaaca acgattccct gatctgtttt tgataagatt
     5461 tttgagtctt tggttaaaat aaacccatca tctgtaggaa aatcgacacc cgccatacct
     5521 ttgtgagtct tgtttgtctt tttgcttttt ttaatcggtt taattttgtt tgacgtcatt
     5581 cccttacgtg attgtttcgt tttaatggga tatgtaccat tacctcgtga ttgacaagat
     5641 atcaaagtca actgagatga taacaataga ccaactaaaa taataacttt tttcgttttc
     5701 attcaaccct cctttttatt taactggtta agtatatcac atcacttgtt tttcctcaag
     5761 ctctttttag gataactatt agttgttgac gagttggagc tctgaagctt caacaaacaa
     5821 tagtttctgt tgttagtagc attacacaaa aaaactaact tttcttttcc tttgaaaata
     5881 agatctttta taatatacta tacatatgaa aacatcagaa aaaatttatc aattactgtc
     5941 acaaaccgat gacttcgtca gtggggaata tctagcagat caactcagta tctctcgtac
     6001 atccgtttgg aaatccatca aaagtctcga aaatcagggg attcaaattg attctttaaa
     6061 acacaagggc taccgcatgg tacaaggtga tattttatta cccaaaacca ttagccaagg
     6121 gcttgggatg ccagtcacct atacccctca cagccaatct acccaattag atgccaaaca
     6181 aggaatcgaa gctcataaca gcgctccaag gctttaccta gctcctagcc aagaagctgc
     6241 caaaggacgc ctcgatcggc aatttttttc agctagcacc ggtggtattt acatgtccat
     6301 gtacctaaaa cccaatgtcc cttatgctga tatgcctcct tatacgatga tggttgcttc
     6361 cagtattgtc aaagctatct cgcgattaac aggcattgat acagaaatca aatgggtaaa
     6421 cgacatctat ctaggtaacc ataaagttgc agggattctg acagaagcca ttacttctgt
     6481 tgaaactggt ttaatcaccg atgtcattat tggggttggt ctcaactttt ttgtcaccga
     6541 cttcccagaa gcgattgctc aaaaggcagg ttctctcttt accgaaaaac cgactatcac
     6601 gcgcaatgac cttatcattg acatctggaa attattctta tctattcctg tcaaggacca
     6661 tgtcaaagtt tacaaagaaa aatcacttgt tcttaataaa caagtgacct ttacagaaaa
     6721 tagtcaagaa aaacgtgcta ttgcgattga tctcacagat caaggacacc tcattgtaca
     6781 gtttgaaaat ggtgacttcc aaaccttgcg aagcggtgaa atcagtcttt cttcttggga
     6841 gaattagccg tttttaaaat ggttttagtc aattggttaa tggtatgcac tcttcttaaa
     6901 tccctaaaga gcaacaagcc ccaaaataag gcgaagagat aatttccaga gagcaacagg
     6961 tcattaaaaa aataggtttc aaaagcacat acaaaggcca taaaaagaaa ttgtcgaata
     7021 gtcatagctt tattataaca gaaaaaaatg attctatgaa gaatccacac agattgat
//
LOCUS       DATWEK010000059         6493 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.059, whole genome shotgun sequence.
ACCESSION   DATWEK010000059 DATWEK010000000
VERSION     DATWEK010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6493
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.059"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            74..4180
                     /gene="cas9"
                     /locus_tag="VCR92_001709"
     CDS             74..4180
                     /gene="cas9"
                     /locus_tag="VCR92_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922251.1"
                     /note="Cas9, originally named Csn1, is the large,
                     multifunctional signature protein of type II CRISPR/Cas
                     systems. It is well known even to general audiences
                     because its RNA-guided endonuclease activity has made it a
                     popular tool for custom editing of eukaryotic genomes;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR RNA-guided endonuclease Cas9"
                     /protein_id="HEP4268757.1"
                     /translation="MDKKYSIGLDIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIK
                     KNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLE
                     ESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAH
                     MIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSK
                     SRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLD
                     NLLAQIGDQYADLFLAAKNLSDAILLSDILRLNSEITKAPLSASMIKRYDEHHQDLTL
                     LKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLAK
                     LNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPY
                     YVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVL
                     PKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKE
                     DYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLT
                     LFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDF
                     LKSDGFANRNFMQLIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQT
                     VKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKE
                     HPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFIKDDSIDNKV
                     LTRSDKNRGKSNNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKA
                     GFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQF
                     YKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIG
                     KATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLS
                     MPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVV
                     AKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVRKDLIVKLPKYSLF
                     ELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQH
                     KHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGA
                     PAAFKYFDTTIDRKRYTSTKEVLDATFIHQSITGLYETRIDLSQLGGD"
     gene            4180..5049
                     /gene="cas1"
                     /locus_tag="VCR92_001710"
     CDS             4180..5049
                     /gene="cas1"
                     /locus_tag="VCR92_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR-associated endonuclease Cas1"
                     /protein_id="HEP4268758.1"
                     /translation="MAGWRTVVVNTHSKLSYKNNHLIFKDAYKTELIHLSEIDILLLE
                     TTDIVLSTMLVKRLVDENVLVIFCDDKRLPTAMLMPFYGRHDSSLQLGKQMSWSETVK
                     SQVWTTIIAQKILNQSCYLGACSYFEKSQSIMDLYHGLENFDPSNREGHAARIYFNTL
                     FGNDFSRDLEHPINAGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDI
                     MEPFRPLVDKIVYENRNQPFPKIKRELFTLFSDTFSYNGKEMYLTNIISDYTKKVVKA
                     LNNEGKGVPEFRI"
     gene            5046..5387
                     /gene="cas2"
                     /locus_tag="VCR92_001711"
     CDS             5046..5387
                     /gene="cas2"
                     /locus_tag="VCR92_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEP4268759.1"
                     /translation="MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSI
                     YSKLLLNNTANNAMIGRLREHNPNKGNITLLTVTEKQFARMIYLHGERNNCIANSDER
                     LVFLGEAFDES"
     gene            5377..6039
                     /gene="csn2"
                     /locus_tag="VCR92_001712"
     CDS             5377..6039
                     /gene="csn2"
                     /locus_tag="VCR92_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II-A CRISPR-associated protein Csn2"
                     /protein_id="HEP4268760.1"
                     /translation="MNLNFSLLDEPIPLRGGTILVLEDVCVFSKIVQYCYKYEEDSEL
                     KFFDRKMKTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVA
                     TITELIVFECLENELDLEYDEITILELIKSLGVKVETQSDTIFEKCLEILQIFKYLTK
                     KKLLIFVNSGAFLTKDEVASLQEYISLTNLTVLFLEPRELYDFPQYILDEDYFLITKN
                     MV"
     repeat_region   6142..6441
                     /inference="COORDINATES: alignment:crt:1.2"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=6142..6177
                     /rpt_unit_seq="gttttagagctatgctgttttgaatggtcccaaaac"
BASE COUNT         2229 a          959 c         1287 g         2018 t
ORIGIN      
        1 tcattaaaac tattagtgaa atcatcaaac tcattatgga tttaatttaa actttttatt
       61 ttaggaggca aaaatggata agaaatactc aataggctta gatatcggca caaatagcgt
      121 cggatgggcg gtgatcactg atgattataa ggttccgtct aaaaagttca aggttctggg
      181 aaatacagac cgccacagta tcaaaaaaaa tcttataggg gctcttttat ttgacagtgg
      241 agagacagcg gaagcgactc gtctcaaacg gacagctcgt agaaggtata cacgtcggaa
      301 gaatcgtatt tgttatctac aggagatttt ttcaaatgag atggcgaaag tagatgatag
      361 tttctttcat cgacttgaag agtctttttt ggtggaagaa gacaagaagc atgaacgtca
      421 tcctattttt ggaaatatag tagatgaagt tgcttatcat gagaaatatc caactatcta
      481 tcatctgcga aaaaaattgg tagattctac tgataaagcg gatttgcgct taatctattt
      541 ggccttagcg catatgatta agtttcgtgg tcattttttg attgagggag atttaaatcc
      601 tgataatagt gatgtggaca aactatttat ccagttggta caaacctaca atcaattatt
      661 tgaagaaaac cctattaacg caagtggagt agatgctaaa gcgattcttt ctgcacgatt
      721 gagtaaatca agacgattag aaaatctcat tgctcagctc cccggtgaga agaaaaatgg
      781 cttatttggg aatctcattg ctttgtcatt gggtttgacc cctaatttta aatcaaattt
      841 tgatttggca gaagatgcta aattacagct ttcaaaagat acttacgatg atgatttaga
      901 taatttattg gcgcaaattg gagatcaata tgctgatttg tttttggcag ctaagaattt
      961 atcagatgct attttacttt cagatatcct aagattaaat agtgaaataa ctaaggctcc
     1021 cctatcagct tcaatgatta aacgctacga tgaacatcat caagacttga ctcttttaaa
     1081 agctttagtt cgacaacaac ttccagaaaa gtataaagaa atcttttttg atcaatcaaa
     1141 aaacggatat gcaggttata ttgatggggg agctagccaa gaagaatttt ataaatttat
     1201 caaaccaatt ttagaaaaaa tggatggtac tgaggaatta ttggcgaaac taaatcgtga
     1261 agatttgctg cgcaagcaac ggacctttga caacggctct attccccatc aaattcactt
     1321 gggtgagctg catgctattc tgagaagaca agaagacttt tatccatttt taaaagacaa
     1381 tcgtgagaag attgaaaaaa tcttgacttt tcgaattcct tattatgttg gtccattggc
     1441 gcgtggcaat agtcgttttg catggatgac tcggaagtct gaagaaacaa ttaccccatg
     1501 gaattttgaa gaagttgtcg ataaaggtgc ttcagctcaa tcatttattg aacgcatgac
     1561 aaactttgat aaaaatcttc caaatgaaaa agtactacca aaacatagtt tgctttatga
     1621 gtattttacg gtttataacg aattgacaaa ggtcaaatat gttactgagg gaatgcgaaa
     1681 accagcattt ctttcaggtg aacagaagaa agccattgtt gatttactct tcaaaacaaa
     1741 tcgaaaagta accgttaagc aattaaaaga agattatttc aaaaaaatag aatgttttga
     1801 tagtgttgaa atttcaggag ttgaagatag atttaatgct tcattaggta cctaccatga
     1861 tttgctaaaa attattaaag ataaagattt tttggataat gaagaaaatg aagatatctt
     1921 agaggatatt gttttaacat tgaccttatt tgaagatagg gagatgattg aggaaagact
     1981 taaaacatat gctcacctct ttgatgataa ggtgatgaaa cagcttaaac gtcgccgtta
     2041 tactggttgg ggacgtttgt ctcgaaaatt gattaatggt attagggata agcaatctgg
     2101 caaaacaata ttagattttt tgaaatcaga tggttttgcc aatcgcaatt ttatgcagct
     2161 gatccatgat gatagtttga catttaaaga agacattcaa aaagcacaag tgtctggaca
     2221 aggcgatagt ttacatgaac atattgcaaa tttagctggt agccctgcta ttaaaaaagg
     2281 tattttacag actgtaaaag ttgttgatga attggtcaaa gtaatggggc ggcataagcc
     2341 agaaaatatc gttattgaaa tggcacgtga aaatcagaca actcaaaagg gccagaaaaa
     2401 ttcgcgtgag cgtatgaaac gtattgaaga aggtatcaaa gaattaggaa gtcagattct
     2461 taaagagcat cctgttgaaa atactcaatt gcaaaatgaa aagctctatc tctattatct
     2521 ccaaaatgga agagacatgt atgtggacca agaattagat attaatcgtt taagtgatta
     2581 tgatgtcgat cacattgttc cacaaagttt cattaaagac gattcaatag acaataaggt
     2641 cttaacgcgt tctgataaaa atcgtggtaa atcgaataac gttccaagtg aagaagtagt
     2701 caaaaagatg aaaaactatt ggagacaact tctaaacgcc aagttaatca ctcaacgtaa
     2761 gtttgataat ttaacgaaag ctgaacgtgg aggtttgagt gaacttgata aagctggttt
     2821 tatcaaacgc caattggttg aaactcgcca aatcactaag catgtggcac aaattttgga
     2881 tagtcgcatg aatactaaat acgatgaaaa tgataaactt attcgagagg ttaaagtgat
     2941 taccttaaaa tctaaattag tttctgactt ccgaaaagat ttccaattct ataaagtacg
     3001 tgagattaac aattaccatc atgcccatga tgcgtatctt aatgccgtcg ttggaactgc
     3061 tttgattaag aaatatccaa aacttgaatc ggagtttgtc tatggtgatt ataaagttta
     3121 tgatgttcgt aaaatgattg ctaagtctga gcaggaaata ggcaaagcaa ccgcaaaata
     3181 tttcttttac tctaatatca tgaacttctt caaaacagaa attacacttg caaatggaga
     3241 gattcgcaaa cgccctctaa tcgaaactaa tggggaaact ggagaaattg tctgggataa
     3301 agggcgagat tttgccacag tgcgcaaagt attgtccatg ccccaagtca atattgtcaa
     3361 gaaaacagaa gtacagacag gcggattctc caaggagtca attttaccaa aaagaaattc
     3421 ggacaagctt attgctcgta aaaaagactg ggatccaaaa aaatatggtg gttttgatag
     3481 tccaacggta gcttattcag tcctagtggt tgctaaggtg gaaaaaggga aatcgaagaa
     3541 gttaaaatcc gttaaagagt tactagggat cacaattatg gaaagaagtt cctttgaaaa
     3601 aaatccgatt gactttttag aagctaaagg atataaggaa gttagaaaag acttaatcgt
     3661 taaactacct aaatatagtc tttttgagtt agaaaacggt cgtaaacgga tgctggctag
     3721 tgccggagaa ttacaaaaag gaaatgagct ggctctgcca agcaaatatg tgaatttttt
     3781 atatttagct agtcattatg aaaagttgaa gggtagtcca gaagataacg aacaaaaaca
     3841 attgtttgtg gagcagcata agcattattt agatgagatt attgagcaaa tcagtgaatt
     3901 ttctaagcgt gttattttag cagatgccaa tttagataaa gttcttagtg catataacaa
     3961 acatagagac aaaccaatac gtgaacaagc agaaaatatt attcatttat ttacgttgac
     4021 gaatcttgga gctcccgctg cttttaaata ttttgataca acaattgatc gtaaacgata
     4081 tacgtctaca aaagaagttt tagatgccac ttttatccat caatccatca ctggtcttta
     4141 tgaaacacgc attgatttga gtcagctagg aggtgactga tggctggttg gcgtactgtt
     4201 gtggtaaata cccactcgaa attatcctat aagaataatc atctgatttt taaggatgcc
     4261 tataaaacgg agctgatcca tttatcagaa attgatattt tgttattaga aacgaccgat
     4321 attgtcttgt ccactatgct ggtaaaacgg ctagtggatg agaatgtcct tgtcatattc
     4381 tgtgatgata aacgattacc aacagctatg ctgatgcctt tttatggtcg tcatgattcg
     4441 agtttacagc ttgggaaaca aatgtcctgg tcagaaacag tcaaatcgca ggtttggacg
     4501 acgattattg ctcaaaagat tttgaatcaa tcttgctatc taggagcatg ctcctatttt
     4561 gaaaaatccc aatctattat ggatttatat catggtttgg aaaattttga tccgagtaat
     4621 cgagaagggc atgcagcgag aatttatttt aatacacttt ttgggaacga tttctcaaga
     4681 gatttggagc atccaatcaa tgcaggtctg gattatggtt atactttatt attgagtatg
     4741 tttgcgcgtg aagtggttgt gtctggatgt atgactcagt ttgggcttaa acacgctaat
     4801 cagtttaatc agttcaattt tgctagcgat attatggaac catttaggcc tttggtggat
     4861 aagattgttt atgaaaatcg aaatcagcct tttcccaaaa taaagagaga gttatttact
     4921 ttgttttcag atacattttc atataatggt aaagagatgt atctcacgaa tattattagc
     4981 gattatacta aaaaagttgt caaagctctg aataatgaag ggaaaggagt tcctgaattt
     5041 aggatatgag ttatagatat atgagaatga tacttatgtt tgatatgccg acggacaccg
     5101 ctgaggaacg aaaagcctat cgaaaatttc ggaaattttt acttagtgaa gggtttatca
     5161 tgcatcaatt ttctatttat agtaagttgc tgttgaataa tacagctaac aatgccatga
     5221 ttggtcggct gagggagcat aatcctaata aaggaaatat tacattacta acggtcacag
     5281 aaaaacagtt tgcacgaatg atttatttac atggtgaaag aaataattgt attgcaaact
     5341 ccgatgaaag acttgtattt cttggggagg cttttgatga atcttaattt ttccttacta
     5401 gatgaaccga ttccattaag aggcggtaca attcttgtgc tcgaagatgt ctgtgtattt
     5461 tcaaaaatag tgcaatattg ttacaaatat gaggaagatt ctgaacttaa attttttgat
     5521 cgcaagatga aaaccatcaa agaatcagaa atcatgcttg taacagatat tttaggattt
     5581 gatgttaact cctcaaccat tttaaaattg attcatgcag atttagaatc tcaatttaat
     5641 gagaaacccg aagtgaaatc gatgattgac aaattggttg ctacgattac agaactgatt
     5701 gtctttgaat gcttagaaaa tgaattagat ttagagtatg atgaaatcac aatcctggaa
     5761 ttgattaagt ccttaggagt aaaagtagaa acgcaaagtg atactatttt tgaaaaatgt
     5821 ctagagatac ttcaaatttt caaatatctc actaagaaaa agttgcttat ttttgtcaat
     5881 agcggagctt ttctaacaaa ggatgaagtg gctagtttac aagagtatat atcattgaca
     5941 aatttaacag ttctcttttt agaaccacgt gaactatatg attttccgca gtatatttta
     6001 gatgaagatt atttcttaat aactaaaaat atggtataat actcttaata aatgcagtaa
     6061 tacaggggct tttcaagact gaagtctagc tgagacaaat agtgcgatta cgaaattttt
     6121 tagacaaaaa tagtctacga ggttttagag ctatgctgtt ttgaatggtc ccaaaactgc
     6181 tccagatgga tttttaaact gattattgtt ttagagctat gctgttttga atggtcccaa
     6241 aactagaaat tgacaatgct ttttcttttg tctgttttag agctatgctg ttttgaatgg
     6301 tcccaaaaca atagagctag acaaaaaatt gagtttgacg ttttagagct atgctgtttt
     6361 gaatggtccc aaaacgacat attaacgtcc tttctcctgc tttccgtttt agagctatgc
     6421 tgttttgaat ggtctccatt caacattgcc gatgataact tgagaaagag ggttaatacc
     6481 agcagtcgga tac
//
LOCUS       DATWEK010000060         6489 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.060, whole genome shotgun sequence.
ACCESSION   DATWEK010000060 DATWEK010000000
VERSION     DATWEK010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6489
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.060"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..865
                     /locus_tag="VCR92_001713"
     CDS             <1..865
                     /locus_tag="VCR92_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEP4268761.1"
                     /translation="HVTDDLKPFQVRDLVSGHLERIQEEVEKKYPNAGFNSDKYNGLK
                     ESNSLLSDGFEVKSGNLIFDKKLTIPLTTLFDVINPDFLANSDRAAYDNYRTYKEQHP
                     KKLVALTFDDGPDPTTTPQVLDILAKYQAKGTFFMIGSKVVNNENLTKRVSDAGHEIA
                     NHTWDHPNLTNLSVSEIQHQVNMTNQAIEKACGKKPRYLRPPYGATNATVQQSSGLTQ
                     MLWTVDTRDWENHSTDGIMTNVKNQLQPGGVVLMHDIHQTTINALPAVMEYLKAEGYE
                     CVTVSELYAHQ"
     gene            complement(975..2060)
                     /locus_tag="VCR92_001714"
     CDS             complement(975..2060)
                     /locus_tag="VCR92_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEP4268762.1"
                     /translation="MITKFPPQWQEKLDQVAFTHLTPIQEQAFQPIVDGKNFLGISPT
                     GTGKTLAYVFPSLLALTPKKSQQLLILAPNTELAGQIFEVTKDWAQPLGLTAQLFISG
                     TSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMSVNTIVLDEYDELLGDSQYDFV
                     QKISHYVPRDHQMVYMSATNKVDQTSLAPNTFCIDLSEQTNDAIQHFYLMVDKRERTD
                     LLRKFANIPHFRALVFFNSLSDLGATEERLQYNGAAAVSLASDINVKFRKTILEKFKS
                     HQLSLLLATDLVARGIDIDNLDYVIHFDVARDKENYTHRAGRTGRMGKSGIVITFVSH
                     PEDLKKLKKFAKVSEISLKNQQLHFIN"
     gene            2158..2784
                     /gene="udk"
                     /locus_tag="VCR92_001715"
     CDS             2158..2784
                     /gene="udk"
                     /locus_tag="VCR92_001715"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEP4268763.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYK
                     DQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQ
                     DPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV"
     gene            2864..3127
                     /locus_tag="VCR92_001716"
     CDS             2864..3127
                     /locus_tag="VCR92_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEP4268764.1"
                     /translation="MLLIWLGLLFVWNELVFVIYAFDKRKAIKKKRRISERNLLVITV
                     LFGGFGALLAAKKYHHKTRKWYFVITWYTSILLTLLVTYIFMK"
     gene            complement(3180..3989)
                     /locus_tag="VCR92_001717"
     CDS             complement(3180..3989)
                     /locus_tag="VCR92_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEP4268765.1"
                     /translation="MKQITQQKWLRYGLFIALVLNGIELELLGLTANNLSFKEAFALI
                     LTISLLGIYLIPFAAAIFYLSKKFHMNLNVIIVSCLSGLYISGFLASCGNHLVGQFWS
                     YIIPSKDALKLWGDALTAPIVEEPIKASSAILVITLFPRLTLKEKLVVALLSGMGFQL
                     AEDIRYLIQAKSIDSLVPTAIERISTAVTSHWVHTAIFTIGAYLLLKGSNLFSKQQQI
                     FWLLSPLVLHFIWNSPLTSIPGMTVLLGTLILLIFGDLFQKINTLDDDVLF"
     gene            4134..4631
                     /locus_tag="VCR92_001718"
     CDS             4134..4631
                     /locus_tag="VCR92_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEP4268766.1"
                     /translation="MNKSKKIEQYQLMIAQAKELFANESNALANLSNASALLNMTLPN
                     SVFAGFYLFDGQELILGPFQGRVSCVHIKLGKGVCGESAQSRRTIIINDVKQHANYIS
                     CDAAAMSEIVVPMVKEGHLIGVLDLDSSLVADYDEVDQEYLEAFVDLFLEKTTFTFNM
                     FGVKN"
     gene            4631..6316
                     /gene="dnaX"
                     /locus_tag="VCR92_001719"
     CDS             4631..6316
                     /gene="dnaX"
                     /locus_tag="VCR92_001719"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEP4268767.1"
                     /translation="MYQALYRKYRSQTFDEMVGQSVISTTLKQAVESGKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVDGEPCNQCDICRDITNGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHK
                     IPATILSRVQRFEFKAIKQKAIREHLAWVLDKEGIAYEVDALNLIARRAEGGMRDALS
                     ILDQALSLSPDNQVTIAIAEEITGSISMLALGDYVRYVSQEQATQALAALETIYDSGK
                     SMSRFATDLLTYLRDLLVVKAGGDNQRQSAVFDTNLSLSIDRIFQMITVVTSHLPEIK
                     KGTHPRIYAEMMTIQLAKEEGVALPSGLSSDVTTEVEGLKRELNQLKQALAQLQASPS
                     PSHAPVKPAQAKPKLTTYKIDRVKILKIMEETVQDSQQSRQYLDALKTAWNEILDSIS
                     AQDRALLMGSEPVLANSENAILAFEAAFNAEQAMKRTDLNAIFGNIMSKAAGFSPNIL
                     AVPKADFHHIRSEFALQLKTQKASDPTEETIEETLEIPEGFDFLVDKINAVED"
BASE COUNT         2085 a         1097 c         1336 g         1971 t
ORIGIN      
        1 tcacgttaca gacgacttga aaccgtttca ggtaagggat ctagtatcag gacatttaga
       61 aagaatacaa gaagaagttg aaaaaaaata tccaaatgct ggttttaata gcgataagta
      121 caatggctta aaagaatcta attctttatt aagcgatggc tttgaggtaa aatcgggaaa
      181 ccttattttt gataaaaagc taacgatacc tttgacgaca ttatttgatg ttattaatcc
      241 agatttttta gcaaatagcg atagagctgc gtatgataat tataggacct acaaagaaca
      301 gcatcccaaa aaactagttg cattaacgtt tgatgatggt ccagatccga cgacgactcc
      361 tcaagtttta gatattttgg caaaatacca ggctaaggga actttcttta tgataggttc
      421 aaaagttgtg aataatgaaa accttactaa acgtgttagc gacgctggcc atgaaattgc
      481 taatcatact tgggatcatc ccaatctgac taatctttca gtcagcgaga ttcaacatca
      541 agttaatatg acgaaccagg ctattgaaaa agcttgtggc aagaaacctc gctatttacg
      601 ccctccatac ggagctacaa atgcaactgt tcagcaatcc tcaggattaa cacaaatgct
      661 ttggacggtt gatacaagag attgggaaaa tcatagcact gatggcatta tgactaatgt
      721 caaaaaccaa ttgcaaccgg gaggagttgt tttaatgcat gatattcatc aaacaactat
      781 caatgctttg ccggcagtta tggaatatct aaaagcagaa ggatacgaat gtgtgactgt
      841 atcagaactc tatgcgcatc agtaagtaat atcgttatgt ttctttagaa ttgatatact
      901 aaacaatcca attactttga agtaattgga ttgttgtttt tagtagccct tgattaagtt
      961 ttgtttttta acaactagtt gatgaaatga agttgttgat ttttgaggga gatttcagag
     1021 actttagcaa attttttcaa ttttttgagg tcttcagggt ggctaacaaa ggtaataacg
     1081 ataccagatt ttcccatacg gccggttcgt ccagctctgt gagtataatt ttccttatca
     1141 cgagcaacat caaaatgaat gacatagtca agattatcaa tatcaatgcc ccgagcaaca
     1201 agatccgtag ctaacaataa ggagagttgg tgggatttga atttttcgag aatggtttta
     1261 cggaatttga cattgatgtc actcgctaag gaaaccgcag cagctccatt atattggaga
     1321 cgttcttccg tagcacccaa atcagataaa ctgttgaaaa agactaaagc tctaaaatga
     1381 ggaatattag caaattttcg taataaatcg gtacgttcgc gcttgtcaac catgaggtaa
     1441 aaatgctgaa tagcatcgtt ggtttgctct gaaagatcga tgcagaatgt atttggagct
     1501 aaggaagttt gatccacctt attagtagca ctcatgtata ccatttgatg atctcgagga
     1561 acatagtggc taattttttg aacaaaatca tattgggaat cacctaatag ttcgtcatat
     1621 tcatctaaaa caatggtgtt gacagacatc atcttgattt ttttcaattt aatcagttca
     1681 aaaatgcgtc caggggtccc aatcaggatt tcaggacctt ttttgaggcg ttcgatttga
     1741 cgtttttgac tggttccaga aataaagagt tgtgccgtta agcctagtgg ctgtgcccaa
     1801 tcctttgtga cttcaaaaat ttggccagct aattcggtat taggggctaa aatgagtagt
     1861 tgttgggact ttttaggcgt cagtgccaat agactaggaa agacataagc taaggtcttg
     1921 cccgtcccag tagggctaat accaaggaaa tttttaccat caacaatagg ttgaaaggcc
     1981 tgttcttgga ttggcgttaa atgggtaaat gcaacttggt caagtttttc ttgccattga
     2041 gggggaaatt tagtgatcat gcgtcttcct tttactattg tttctatatt cattatagca
     2101 ttatagtctc aattttggta aaatagtgag aaagactttt tagatttgga gtttaaaatg
     2161 cttaaaaaac cgattattat tggtgtaact ggtggttcag gtggcggtaa aacaagtgtg
     2221 tcacgcgcta ttttggacag ttttccaaat gctcgtattg cgatgattca acacgattct
     2281 tactataaag atcagtctca catgagtttt gaagaaaggg tcaaaaccaa ttatgaccat
     2341 cctctagctt ttgatacaga ttttatgatt cagcaactaa aagaattatt agctggtaga
     2401 cctgtagata ttcctatcta tgattacaaa aagcataccc gcagtaatac gacctttcgt
     2461 caggatcctc aggatgttat tattgttgaa ggtattcttg tcctagaaga tgagcgtttg
     2521 cgagatttga tggatatcaa gctctttgta gacacagatg acgatattcg tattattcgt
     2581 cgtattaagc gtgacatgat ggaacgtggc agaagcttag aaagtattat tgatcagtac
     2641 acaagcgtgg taaagcctat gtatcatcag tttattgagc caagtaaacg ctatgctgat
     2701 attgttattc cagagggagt tagtaatgtc gttgctattg atgttattaa tagtaaaatt
     2761 gcgagtattc ttggagaagt atagtggaag tggctgagta gattatttaa atctgctctt
     2821 ttattgttgt gctcttcata gagaaaggga tcataaaata gaaatgttat taatttggct
     2881 tggattacta tttgtttgga atgaactcgt gtttgtcata tatgcctttg ataaaagaaa
     2941 agccataaaa aagaaacggc gtattagtga aagaaactta ttagtgataa cagttttgtt
     3001 tggaggtttt ggagcattac ttgcagctaa aaagtaccac cataaaacca gaaagtggta
     3061 ctttgtcatc acttggtata ctagtatttt gttgacatta ctagtaactt atatctttat
     3121 gaagtgagtc acttaaaaga cccttaatca gtattattta gtcaaggctc ttttatagtt
     3181 taaaaaagca catcatcgtc aagggtgttg attttttgaa aaagatcacc aaagattaaa
     3241 aggattaatg ttcctagtaa aactgtcatg ccaggaatgc ttgttagagg agagttccag
     3301 atgaaatgta gcaccagagg acttaataac cagaaaattt gttgctgttt tgaaaaaagg
     3361 ttagaaccct ttaataataa gtatgctcca atggtaaaaa tagctgtatg tacccaatgt
     3421 gaagtcacag cagtgctaat acgttcaata gcagtcggta cgagactatc tatagatttt
     3481 gcttgaatca aataacggat atcttctgct agttgaaagc ccatgccaga aagtaaagca
     3541 acaactaatt tttctttaag agtaagtcta ggaaataaag taattactaa aatagccgaa
     3601 gaagccttaa tgggctcttc gacaataggg gcagttaaag catctcccca aagctttaaa
     3661 gcgtctttag aagggatgat gtatgaccaa aattgtccta cgagatggtt cccacaagaa
     3721 gctaaaaaac ctgaaatata aagtccgcta agacagctaa caataataac attcaggttc
     3781 atatgaaatt ttttacttaa ataaaaaata gctgctgcaa atggaattaa gtaaatgcct
     3841 aatagactaa tggttagtat tagagcaaaa gcttctttaa aggaaaggtt gttagctgtc
     3901 agtcctaaca attcaagttc aataccattt aaaactaaag caataaaaag accgtatcgt
     3961 aaccatttct gttgagtgat ttgtttcacg aaaacctcct aatattaaga tgatattaat
     4021 aatattgaaa attatatcat aaacaacctc aaaaaccatt ttaaaaattg actgaagcga
     4081 aagatagtcg taaaaaatac tcgaatagac ccagatatgc tataataaaa ggtatgaata
     4141 agtctaaaaa aattgagcaa taccaactaa tgatagcaca ggcaaaagag ctgtttgcga
     4201 atgaatcaaa tgctttggct aatttgtcaa atgccagcgc cctgttaaac atgacactac
     4261 ccaattctgt ttttgcggga ttttaccttt ttgatgggca ggaattaatt cttggccctt
     4321 ttcaaggtag ggtttcttgc gtccatatca agcttggtaa aggtgtttgt ggcgaatcag
     4381 ctcagtctcg tcgaaccatt attataaatg atgtgaagca gcatgccaac tatatttcct
     4441 gtgatgcggc agccatgagt gaaattgttg tgcctatggt gaaagaaggc catttgattg
     4501 gggtgctgga cttggattct agccttgtag ctgattatga tgaggttgat caagaatact
     4561 tagaggcctt tgtggaccta tttcttgaaa agaccacgtt tacctttaac atgtttggag
     4621 ttaaaaactg atgtatcaag ctctttatcg gaaataccgg agccaaacgt ttgacgaaat
     4681 ggtgggacaa tcggttattt ccacaacttt aaagcaggca gttgaatctg gcaagattag
     4741 ccatgcttat cttttttcag gtcctagagg gactgggaaa acaagtgcgg caaagatttt
     4801 tgcaaaggcc atgaattgtc ctaaccaagt cgatggtgaa ccctgtaatc aatgcgatat
     4861 ttgccgagat atcacgaatg gaagcttgga agatgtgatt gaaattgatg ctgcctcgaa
     4921 taatggtgtt gatgaaattc gtgacattcg agacaaatca acctatgcgc caagtcgtgc
     4981 gacttataag gtttatatta ttgatgaggt tcacatgtta tcaacagggg cttttaatgc
     5041 gcttttgaaa actttggaag aaccgacaga aaatgttgtc tttatcttgg caacaacgga
     5101 attgcataaa attccagcca ctattttatc tcgtgtgcaa cgctttgaat tcaaagctat
     5161 taagcaaaaa gctattcgag agcatttagc ctgggttttg gacaaagaag gtattgccta
     5221 tgaggtggat gctttaaatc tcattgcaag gcgagcagaa ggaggcatgc gtgatgcttt
     5281 atctatttta gatcaggctt tgagcttgtc accagataat caggtcacca ttgcaattgc
     5341 cgaagaaatt acaggttcta tttccatgct tgctctgggt gactatgttc gatatgtctc
     5401 ccaagaacag gctacgcaag ctctggcagc cttagagacc atttatgata gtgggaagag
     5461 catgagccgc tttgcgacag atttattgac ctatctgcgt gatttattgg tggttaaagc
     5521 tggcggtgac aatcagcgtc agtcagctgt ttttgatacc aatttgtctc tctcgataga
     5581 tcgtatattc caaatgataa cagttgttac tagtcatctc cctgaaatca aaaagggaac
     5641 ccatcctcgg atttatgccg aaatgatgac tattcagcta gctaaagaag aaggagtagc
     5701 gttaccatca ggtttgtcat cagatgtgac gactgaagtt gagggactta aacgtgaact
     5761 taatcagctt aagcaagcct tggcacaatt gcaagccagt cccagtccct cacatgctcc
     5821 tgtaaaacca gcacaggcta aaccgaaact aaccacttac aagattgatc gggtgaaaat
     5881 actgaaaatc atggaagaaa cggttcaaga tagtcagcaa tcacgccaat acttggatgc
     5941 cctaaaaaca gcttggaatg aaattttaga cagtatctca gctcaagata gagccttact
     6001 aatgggatca gagcctgttc tggccaatag tgagaatgct attttagctt ttgaagctgc
     6061 ttttaatgct gagcaagcaa tgaagcgtac tgatttgaat gcgatattcg gcaacattat
     6121 gagcaaagca gcaggcttct cacctaatat tttggcagtc cctaaagctg attttcatca
     6181 cattcgttct gagtttgcct tacaattgaa aactcaaaag gcttctgacc ctacagaaga
     6241 gacgatagaa gaaacccttg agattccaga aggctttgat tttctagttg ataaaattaa
     6301 tgccgttgag gattaaacat tattagctgt taatgaacca gtaacgctat aaaggtaagc
     6361 ctattgggct tacctttagc gtttttttat ctaatatacc aagatagttt ttctagccaa
     6421 tcctctaata gtagaagtga aaccaaaaaa gattgatgct ttcttgggta tccaagtcag
     6481 catcaatct
//
LOCUS       DATWEK010000061         6352 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.061, whole genome shotgun sequence.
ACCESSION   DATWEK010000061 DATWEK010000000
VERSION     DATWEK010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6352
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.061"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            61..1249
                     /gene="hasA"
                     /locus_tag="VCR92_001720"
                     /pseudo
     CDS             61..1249
                     /gene="hasA"
                     /locus_tag="VCR92_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106926.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronan synthase HasA"
     gene            1285..2493
                     /gene="hasB"
                     /locus_tag="VCR92_001721"
     CDS             1285..2493
                     /gene="hasB"
                     /locus_tag="VCR92_001721"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase HasB"
                     /protein_id="HEP4268768.1"
                     /translation="MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSP
                     IQDEYIEDYLKSKQLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIK
                     EVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFDNTYLALRVAYF
                     NELDTYAESRKLNSHMIIQGISHDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIP
                     QTLIEAIVSSNNVRKSYIAKQIINVLEERESPVKVVGVYRLIMKSNLDNFRESAIKDV
                     IDILKSKDIKIIIYEPMLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNK
                     VYSRDIFNRD"
     gene            2675..3589
                     /gene="hasC"
                     /locus_tag="VCR92_001722"
     CDS             2675..3589
                     /gene="hasC"
                     /locus_tag="VCR92_001722"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     HasC"
                     /protein_id="HEP4268769.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKNELLKLVDETTAINLHFIR
                     QSHPRGLGDAVLQAKAFVGNEPFVGMLGDDLMDITNASAKPLTKQLMEDYDKTHASTI
                     AVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIF
                     DILERQTPGAGNEVQLTDAIDTLNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEH
                     PEVKEDLKNYIIKLGKALEKSKVPTHSK"
     gene            3897..4310
                     /gene="yaaA"
                     /locus_tag="VCR92_001723"
     CDS             3897..4310
                     /gene="yaaA"
                     /locus_tag="VCR92_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEP4268770.1"
                     /translation="MIYKLFTEFITLQALLKELGIIQSGGAIKGFLAETTVLFNGEDE
                     KRRGKKIRIGDKISLPDQDLIITIVEPSQEEKEQFAEEIAEKTRVAALVKQMNQANKK
                     TSSKHKNRQSTTKKSLRATKKTKGKPTAPVRFPGI"
     gene            4312..5418
                     /gene="recF"
                     /locus_tag="VCR92_001724"
     CDS             4312..5418
                     /gene="recF"
                     /locus_tag="VCR92_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEP4268771.1"
                     /translation="MWIKELELKHYRNYDHLLASFSSGLNVFIGNNAQGKTNFLEAIY
                     FLSLTRSHRTRADKELIHFDHSTVSLTGKIQRISGTVDLEINLSDKGRVTKINALKQA
                     KLSDYIGTMMVVLFAPEDLQLVKGAPSLRRKFIDIDLGQIKPVYLSELSHYNHVLKQR
                     NSYLKSAQQIDAAFLAVLDEQLAGYGARVMEHRIDFINALEKEANTHHQAISNGLESL
                     SLSYQSSVVFDKKTNIYQQFLHQLEKNHQKDFFRKNTSVGPHRDNLAFYINGMNANFA
                     SQGQHRSLILSLKMAEVSLMKALTGDNPILLLDDVMSELDNTRQTKLLETVIKENVQT
                     FITTTSLDHLSQLPEGIRIFHVTKGTVQVDSDIH"
     gene            complement(5475..6338)
                     /locus_tag="VCR92_001725"
     CDS             complement(5475..6338)
                     /locus_tag="VCR92_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEP4268772.1"
                     /translation="MEGIFYALIPMFTWGSIGFVSNKIGGKPSQQTLGMTFGALLFSL
                     AVWLIVRPEMTLQLWLFGILGGFIWSIGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTRPMQFVVGSLALLLLIIGFYFSSKQDDANAQVNHLHNFSKGFRALTYS
                     TIGYVMYAVLFNNIMKFEVLSVILPMAVGMVLGAITFMSFKISIDQYVIKNSVVGLLW
                     GIGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVVTGIICFI
                     VGAILLGVVKS"
BASE COUNT         2207 a         1130 c         1085 g         1930 t
ORIGIN      
        1 aaaaaaactt taattgtttt atcctttatt tttttgatat ctatcttgat ttatctaaat
       61 atgtatctat ttggaacatc aactgtagga atttatggag taatattaat aacctatcta
      121 gttattaaac ttggattatc tttcctttat gagccattta aaggaaatcc acatgactat
      181 aaagttgctg ccgtaattcc ttcttaataa tgaagatgcc gagtcattat tagaaactct
      241 taaaagtgtg ttagcacaga cctatccgtt atcagaaatt tatattgttg atgatgggag
      301 ttcaaacaca gatgcaatac aattaattga agagtatgta aatagagaag tggatatttg
      361 tcgaaacgtt atcgttcacc gttcccttgt caataaagga aaacgccatg ctcaagcgtg
      421 ggcatttgaa agatctgacg ctgacgtttt tttaaccgta gattcagata cttatatcta
      481 tccaaatgcc ttagaagaac tcctaaaaag cttcaatgat aagacagttt atgctgcaac
      541 aggacatttg aatgctagaa acagacaaac taatctatta acgcgactta cagatatccg
      601 ttacgataat gcctttgggg tggagcgtgc tgctcaatca ttaacaggta atattttagt
      661 ttgctcagga ccattgagta tttatcgacg tgaagtgatt attcctaact tagagcgcta
      721 taaaaatcaa acattcctag gtttacctgt tagcattggg gatgatcgat gtttaacaaa
      781 ttatgctatt gatttaggac gcactgtcta ccaatcaaca gctagatgtg atactgatgt
      841 acctttccaa ttaaaaagtt atttaaagca acaaaatcga tggaataaat ctttttttag
      901 agaatctatt atttctgtta aaaaaattct ttctaatccc atcgttgcct tatggactat
      961 tttcgaagtc gttatgttta tgatgttgat tgtcgcaatt gggaatcttt tgtttaatca
     1021 agctattcaa ttagacctta ttaaactttt tgccttttta tccatcatct ttatcgttgc
     1081 tttatgtcgt aatgttcatt atatggtcaa acatcctgct agttttttgt tatctcctct
     1141 gtatggaata ttacacttgt ttgtcttaca gcccctaaaa ctttattctt tatgcaccat
     1201 taaaaatacg gaatggggaa cacgtaaaaa ggtcactatt tttaaataat atatgcatcg
     1261 agtagttaga gaaggagtaa ttttatgaaa atagcagttg ctggatcagg atatgttgga
     1321 ttatcactag gagttctttt atcacttcaa aacgaagtca ctattgttga tattcttcct
     1381 tctaaagttg ataagattaa taatggctta tcaccaattc aagatgaata tattgaagat
     1441 tacttaaaaa gtaagcaatt atctattaaa gcaactttag atagcaaagc agcttataaa
     1501 gaagcggaac tggtcattat tgccacacct acaaattaca acagtagaat taattatttt
     1561 gatacacagc atgttgaaac agttatcaaa gaggtactaa gcgttaatag ccatgcaact
     1621 cttatcatca aatcaacaat tccaataggt ttcattactg aaatgagaca gaaattccaa
     1681 actgatcgta ttatcttcag ccctgaattt ttaagagagt ctaaagcttt atatgacaac
     1741 ttatatccaa gccgaattat tgtttcttgt gaagaaaacg attctccaaa agtaaaggca
     1801 gacgcagaaa aatttgcact tttattaaag tctgcagcta aaaaaaataa tgtaccagta
     1861 cttattatgg gagcttcaga agctgaagca gtaaaactat ttgacaatac ttatttagcg
     1921 ttaagggtag cttattttaa tgagttagac acttacgcag aatcgagaaa attaaatagt
     1981 cacatgatta ttcaaggaat ttctcatgat gatcgaatag gaatgcatta taataaccca
     2041 tcatttggtt atggaggtta ttgtctacct aaagatacga agcaattatt ggcaaattac
     2101 aataatattc cccaaacgct aattgaagct atcgtttcat caaataatgt gcgcaagtcc
     2161 tatattgcta agcaaattat caacgtctta gaagagcggg agtccccagt aaaagtagtc
     2221 ggggtttacc gtttaattat gaaaagtaac ttagataatt ttagagaaag tgctatcaaa
     2281 gatgttattg acattcttaa aagtaaagac attaagataa ttatttatga gccaatgtta
     2341 aacaaacttg aatctgaaga tcaatctgta cttgtaaatg atttagagaa tttcaagaaa
     2401 caagcaaata ttatcgtaac taatcgctat gataatgaat tacaagatgt taaaaataaa
     2461 gtttacagta gagatatttt taatagagac tagccatgtc ttcatctata acaataatat
     2521 tcatttttac tttaaaagaa ctgcagttgg tggtatgatt gagcactatg aaatagtcga
     2581 aaaatcatat gaaaacgtaa catgatgtca aatgaattcc gttctgaaaa cgaatgtcac
     2641 taagccatag attataaaaa gtgaggagtt actgatgacc aaagtcagaa aagccattat
     2701 tcctgctgca ggtctaggaa cacgtttttt acctgctacc aaagctcttg ccaaagagat
     2761 gttgcccatc gttgataaac caaccatcca gtttatcgtc gaagaagcgc taaaatctgg
     2821 catcgaggaa atccttgtgg tgaccggaaa agctaaacgc tctatcgagg accattttga
     2881 ttcaaacttt gaattagaat acaacctcca agctaagggg aaaaatgaac tgttgaaatt
     2941 agtggatgaa accactgcca ttaaccttca ttttatccgt caaagccacc caagaggact
     3001 gggagatgct gtcttacaag ccaaagcctt tgtgggcaat gaaccctttg tgggcatgct
     3061 tggagatgac ttaatggaca ttacaaatgc atccgctaaa cctctcacca aacaactcat
     3121 ggaggactat gacaagacgc atgcatccac tatcgctgtg atgaaagttc ctcatgaaga
     3181 tgtgtctagc tatggggtta tcgctcctca aggcaaggct gtcaagggcc tttacagtgt
     3241 agacaccttt gttgaaaaac cacaaccaga agatgcgcct agtgatttgg ctattattgg
     3301 tcgttacctc ctaacccctg aaatttttga tattttggaa agacagaccc ctggagcagg
     3361 taacgaagtg caactcacag atgctatcga taccctcaat aaaactcagc gtgtctttgc
     3421 acgagaattt aaaggtaatc gttacgatgt tggggataaa tttggattca tgaaaacatc
     3481 tatcgactat gccttagaac acccagaggt caaagaggac ttgaaaaatt acattatcaa
     3541 actaggaaaa gctttggaaa aaagtaaagt accaacacat tcaaagtaat gtgttggtac
     3601 tttacttttt tccttgttta tagcaactta agtttatatc ttgaaaattg tcaacgttcc
     3661 aaaatataaa agttttgtgt tatacaactt tactagaggg acatattaat aataggattt
     3721 atacgtagaa aaatgataaa cataagtaca gcttttgtta aaactaatta acaagaactt
     3781 caaaactaaa tagttatttg gacgagtatg atactttata aatagctctt attcagctat
     3841 tattatttat ttctgtttta tgctataatg acttgaatga caaaatggag atgacaatga
     3901 tatacaaatt atttacagaa tttatcaccc tacaagccct tcttaaagaa ttaggaatta
     3961 tccaaagtgg tggcgctatc aagggatttc tcgctgaaac aaccgttcta tttaatggtg
     4021 aagatgagaa acgtcgaggc aaaaaaatca gaatagggga taagatttct ctacctgacc
     4081 aagacttaat tatcactatt gttgagccta gtcaagaaga aaaagaacaa tttgccgaag
     4141 aaatagctga aaagacacgt gtagcggctc tagtgaaaca aatgaaccaa gctaacaaaa
     4201 agacttcttc taaacataaa aatcgtcaat ctactaccaa aaaatcacta agagcaacta
     4261 agaaaactaa aggtaaacca actgcacctg tccgcttccc aggtatctag tatgtggatt
     4321 aaagagttag agttaaaaca ttatcgcaat tatgaccacc tgcttgcctc attttcgtcg
     4381 ggtttaaatg tctttatcgg taataatgct caaggaaaaa ccaattttct cgaggcaatc
     4441 tattttctat cacttactag aagtcatcgc acgagggctg ataaagaatt gattcatttt
     4501 gatcactcaa ctgtttctct tactggtaag attcagcgta ttagtggtac tgttgattta
     4561 gaaatcaatc tatcagataa aggacgtgtg acaaagatta atgcgctaaa gcaagcaaaa
     4621 ttatctgatt atattggaac gatgatggtt gtgctttttg caccagaaga tttgcaacta
     4681 gttaagggag cacctagcct tcgtcgcaaa tttatcgaca ttgaccttgg tcaaattaag
     4741 cctgtttact tatctgagtt atcccattat aaccacgtgc ttaaacagcg taatagctat
     4801 ttaaaaagtg cccaacaaat tgatgccgct tttctagctg ttctagatga gcaattagct
     4861 ggctatggag cccgtgtcat ggaacatcgt attgatttta tcaatgcgtt agagaaagaa
     4921 gcaaatactc atcaccaagc catctcaaat ggtttagaaa gtctctctct ctcctatcag
     4981 tcgtcagttg tctttgacaa aaaaactaat atttaccaac aatttttaca ccaacttgaa
     5041 aaaaatcatc agaaagattt cttccgtaaa aacactagcg ttggtccaca tcgcgataac
     5101 ttagcctttt acattaacgg gatgaatgct aactttgcta gtcaaggtca gcaccgcagc
     5161 cttattcttt ccttaaaaat ggctgaagtt agtttaatga aggccttgac tggagataac
     5221 cccattcttt tactagacga tgtcatgagc gagctagaca atacacgaca aacaaagtta
     5281 cttgaaacag taattaaaga aaatgtccaa acctttatca caacaacaag tttggatcac
     5341 ctgtcacagt tgccagaagg tatccgtatt tttcacgtaa caaaaggaac cgttcaagtt
     5401 gattctgata ttcactaata acatcaaaaa aagggttcag ttaaactgag cctttttttg
     5461 atattatgtg gcgattaaga tttgaccaca cctaataaaa tagcacctac gataaaacaa
     5521 ataattcctg tgacaaccca acgcatttct tttttggttt tggtttcgcc taggaataaa
     5581 atgcctccaa caatcgaaat gatagcacct aattgtgaga aactaaaggc aatagcaagt
     5641 cctgcttttg atgcagctaa aagcatgaaa atattcccaa tgccccaaag taatccaaca
     5701 acgctatttt taatcacata ctggtcaatg gaaattttaa atgacatgaa agttatagct
     5761 cctaaaacca tacctactgc catgggcaaa atgactgaca aaacttcaaa tttcatgatg
     5821 ttattaaata atacagcata catcacgtaa ccaattgttg aataagtgag cgccctaaat
     5881 ccttttgaaa aattatgaag gtgattgact tgtgcattag catcatcttg tttactagaa
     5941 aagtaaaaac caataatcag aagtaatagt gctagacttc ctactacaaa ttgcataggt
     6001 cttgtccatt catgaaaaac gaggacacca atcaaacttc ccagaacaag ttgagagcca
     6061 cttgacaaag gattggcaac ggagactccc atgtattgca tggcatgaaa ttgaccagtt
     6121 tgaccaattg accagataaa accacccaat attccaaaaa gccaaagttg cagtgtcatc
     6181 tcaggtctaa caattaacca aacagctaat gaaaataata aagccccaaa agtcattcct
     6241 agagtttgtt gcgaaggttt tcctccaatt ttgttactaa caaatccaat gcttccccat
     6301 gtaaacatgg gaataagtgc ataaaaaata ccttccaaaa tgttatctcc tt
//
LOCUS       DATWEK010000062         6228 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.062, whole genome shotgun sequence.
ACCESSION   DATWEK010000062 DATWEK010000000
VERSION     DATWEK010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6228
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.062"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..480
                     /locus_tag="VCR92_001726"
     CDS             <1..480
                     /locus_tag="VCR92_001726"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268773.1"
                     /translation="LTQEQLNALAEKNALIQAEMEAKASIDTVNQWITAYQNYVNANN
                     ADKKKSEQALQDASNRLLQVQYDVKDLKQQWDFIDTYMSVQNEGLIIGKKDGSAYAKF
                     SNDRISLFSGNSEVMHISQGTLNIANGIFTKTIQIGRFRFETHPADVDMLVIRYLGG"
     gene            482..2551
                     /locus_tag="VCR92_001727"
     CDS             482..2551
                     /locus_tag="VCR92_001727"
                     /inference="COORDINATES: protein motif:HMM:NF017688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268774.1"
                     /translation="MATATFSGQYGHNMTLEVWSDWNRQNVASNSSTVNVQARLRTNG
                     YASMYGVTADLTVTINGGSAIEHPAINIGTNSSQLIFGHDYSVPHNGDGTKTVGIKIS
                     VALNAGGYGSSMVAFDLKLPTIPRASTISDVTGTLGSAMTLNINRKNSGFKHTVKYNF
                     GALSGTIATNVDTSVSWTPPLNLATAMPNKTSDWGNITVETYSGSSKIGSATCRLTLN
                     VPDSVKPTLGSITLTDSNATVKNLLNTANTFAQVMSNIQVTFNNASGAYGSTISSYRA
                     EIVGKNQSTNSNNGFLGMMNFNGTVTIRATVTDSRGRTSNAVDVKVTVINYFTPQISF
                     TLQRSGSSSTTLTVTRNARIAPLTVGGKQKNKMIISFKYKEHSATNYTTDTGSAGGTW
                     TTIDNLTNSRANLAATFSTLKTYDIIGKIEDAFTSYEFLATVGTEKFPIAIRPDRVGF
                     GKTPENANAVDSDWVFKYKNKDIQHHQLTRNDGTAIMLTDGSDLNDVTSPGCYNGSNL
                     LHAPANGWNYIRVTKHTNNNGYVLQEAIAFYGNVSAYRVQTNKTWGSWQYYAIQNTVA
                     EFTAVNQTKVYKTTLAGPYGFGIAVTRSGNVVTATMDYIHRSNTNWSGTANETIPVGW
                     RPISQAIINAIGEGGGGTGASLFNGSYVHLSYKPDGSISGRIKLEANPLWFGATISWI
                     TTDPFPS"
     gene            2564..2905
                     /locus_tag="VCR92_001728"
     CDS             2564..2905
                     /locus_tag="VCR92_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000667466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEP4268775.1"
                     /translation="MKLKFGSKSQEFEQDGTVKGTKVTLTNDDGAFYPVMLPADKISL
                     SNAELEELALEVVYQENFRDKYENEKFNEITKELAKHKENSEIAQVTLLDVVTQLYDK
                     GVLTDEIIEEN"
     gene            2931..3089
                     /locus_tag="VCR92_001729"
     CDS             2931..3089
                     /locus_tag="VCR92_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000972859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268776.1"
                     /translation="MMIKLYAINVISGNYQYAKIPKVLKPKVKAQIALMVEDDELLAE
                     LTKENTAE"
     gene            3111..3443
                     /locus_tag="VCR92_001730"
     CDS             3111..3443
                     /locus_tag="VCR92_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015977395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268777.1"
                     /translation="MVGQDIIHEAMRATWTIDKVGGVLAIAIILVILLLISGMIWVIK
                     KLVTGFQETNKELLASNNRIATENQQQMARLTEAVNNLSLETRKDISVLQEKVDDLED
                     VVRNTQMF"
     gene            3456..3782
                     /locus_tag="VCR92_001731"
     CDS             3456..3782
                     /locus_tag="VCR92_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006532419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEP4268778.1"
                     /translation="MNDVILQGIMLILTGFAGFIVKTVKDYLFKEGGEKALRIVEIVA
                     KNAVNAVEQIANEDTKGEQKLNAAKTKVKKALEQYNIYLSDSQLEMFIEAAVKEMNDS
                     WKGENK"
     gene            3779..4372
                     /locus_tag="VCR92_001732"
                     /pseudo
     CDS             3779..4372
                     /locus_tag="VCR92_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006532420.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase"
     gene            4582..5346
                     /locus_tag="VCR92_001733"
     CDS             4582..5346
                     /locus_tag="VCR92_001733"
                     /inference="COORDINATES: protein motif:HMM:NF024784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEP4268779.1"
                     /translation="MSKTKRGVCANCHKVFVVSKKQAERMKQGKSVYCSMECGLEKNG
                     KSRIVVHDIPCCKCGALFTPTRQQYKRYKYNNNVSISYCSDECRYKRDYPFTPHDDYV
                     TVYVGDDEVLLDWDIFEDYGCTIYIIYDKRNGYKNVSVFQNGRKKRLARDILDVTDPN
                     IEIDHINGNTLDNRRSNLRIVTHTENMWNKDNYKNNTSGIKGVHLNKKGLWVARIQVG
                     KDRLFLGSSKDKSVAEKMRLDAEKKYFGKYDRKFLK"
     gene            5397..5636
                     /locus_tag="VCR92_001734"
     CDS             5397..5636
                     /locus_tag="VCR92_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018364452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268780.1"
                     /translation="MPVGLVNWVDENGNNLPDGQDKDFKAGMYFSFEIDEAHIADAGE
                     GGYYGGYYWRKFEFGQFGTVWLSCRDKDDLVNYYN"
BASE COUNT         2090 a         1085 c         1324 g         1729 t
ORIGIN      
        1 ctaacgcaag aacagctgaa tgcgttggca gagaagaatg ctcttattca agctgaaatg
       61 gaagcaaaag cgagcattga tacagtgaac caatggataa ccgcttatca aaactatgtc
      121 aatgctaaca acgcagacaa aaagaaatcc gagcaagcat tacaagacgc atcgaaccgc
      181 ttgttacaag ttcagtatga tgttaaagac ctcaaacagc aatgggattt cattgataca
      241 tatatgagtg ttcaaaatga aggtctaatt atcggtaaaa aagatggttc agcctatgct
      301 aaatttagca atgacagaat tagtttattc tcggggaaca gtgaagtcat gcatatttct
      361 caaggtacac taaacattgc aaacggtatt ttcactaaaa caatccagat cggacgtttc
      421 cgctttgaaa cacacccagc agatgtcgac atgctggtaa taaggtattt aggaggatga
      481 tatggcaaca gctacattta gcggacaata tggacataat atgacattgg aagtctggtc
      541 ggattggaac aggcaaaacg tggcaagcaa cagctctaca gtcaatgtac aagcaaggct
      601 taggacgaat ggttatgcgt caatgtatgg tgttacagct gatttaaccg ttactatcaa
      661 cggtggctcg gctatcgaac atccagctat taatattggc acaaactcat ctcaattgat
      721 ttttggtcat gattatagcg tgccgcataa cggagacggg actaaaacgg ttggtatcaa
      781 aatttctgtt gctttaaacg ctggcggtta cggaagctca atggtcgctt ttgatttaaa
      841 actgccaacg attccccgag caagtacaat cagcgatgtt acaggcacac ttggaagtgc
      901 tatgacactc aatatcaatc gcaagaatag tggttttaag catacggtca aatacaactt
      961 tggggcgcta tctggcacaa tcgcaacgaa tgttgacacc tctgttagct ggacgccacc
     1021 gctcaatctg gctaccgcta tgccaaataa aacgagcgat tggggcaata ttactgtaga
     1081 gacttatagt ggctctagca agattggttc agcaacgtgt aggcttactt tgaatgtccc
     1141 tgacagcgtc aaaccaacgc tcggcagtat aacgctgacg gatagcaatg caacagttaa
     1201 gaacttgtta aatacagcta atacattcgc ccaagtgatg tcaaatatac aagtaacttt
     1261 caacaacgct agtggcgctt atggttcaac gatttcaagc tatcgtgctg aaattgttgg
     1321 caagaatcaa agcacgaatt caaataatgg ctttcttggc atgatgaact ttaatggcac
     1381 ggtgactatt cgagcgacag taacagacag tcgaggacga acgtcaaacg cagttgatgt
     1441 taaagttact gttatcaatt attttactcc acaaatttcg tttacattgc agcgtagcgg
     1501 ttcttctagc acgaccttaa ccgtcacaag aaatgccaga atagctcctt taacagtcgg
     1561 tggaaagcaa aagaacaaaa tgattatttc ttttaagtac aaggagcatt cagctactaa
     1621 ctacacaact gacacaggaa gcgctggtgg aacatggacg actattgata atttaacaaa
     1681 ctctagggct aatttagcag ctacttttag cacactaaag acttatgaca ttatcggtaa
     1741 aatcgaagat gcatttacaa gctatgagtt cttagcaact gttggtacag agaagtttcc
     1801 tattgcaatt agaccagaca gggtaggttt tggcaaaaca ccagaaaatg caaatgctgt
     1861 tgacagcgat tgggtgttta aatacaaaaa caaagacatt caacaccatc agttaactag
     1921 aaacgatggt acagctatca tgttaacaga tggtagtgat ttaaatgatg tcactagccc
     1981 ggggtgttac aatggcagca atctattaca cgctcccgca aatggctgga attatattcg
     2041 tgtgacgaaa cacacaaata ataacggtta tgttttacaa gaagctatcg ctttttatgg
     2101 gaatgtttca gcttatcgcg ttcagaccaa caaaacttgg ggctcttggc aatactatgc
     2161 aatccaaaac acagtagccg agtttacggc agttaatcag acaaaagtgt ataaaacaac
     2221 tttagcaggt ccgtacggtt ttggaatagc tgtaactcgc tctggaaacg tcgtgacagc
     2281 aacaatggat tatattcacc gctcaaatac gaattggagc ggtacggcta acgaaaccat
     2341 accagtcggc tggagaccta taagtcaagc aattattaat gcaataggtg aaggtggtgg
     2401 tggaactggt gcgtcactat ttaacggtag ctatgttcac ttgtcgtaca agcccgacgg
     2461 ctctatcagc ggtcgtatta agctggaagc taatccgctt tggtttggtg ctacaatctc
     2521 atggattacc acagacccat tcccatcata gaaaggagaa aatatgaaac taaaatttgg
     2581 ttcaaaatca caggaatttg agcaagatgg cacggttaaa ggtacgaaag tcaccttgac
     2641 caacgatgac ggtgcattct atcccgtcat gctaccagcc gacaaaatca gcttatctaa
     2701 cgcagagctg gaagagttag cgctggaagt cgtttatcaa gagaattttc gtgataagta
     2761 cgaaaacgag aaattcaatg aaatcacgaa agagcttgca aaacacaagg aaaattctga
     2821 aatagcacaa gttactttat tagatgttgt cactcaactt tatgataaag gagtgctgac
     2881 tgatgaaatt attgaagaaa attaaagaca aaatagaaag aggaatagat atgatgatta
     2941 aactttacgc aattaacgtt atttcaggaa actaccaata tgccaaaatc ccaaaagtgc
     3001 ttaaaccaaa agtcaaagca caaatcgctc tcatggtcga agatgatgag cttttggcag
     3061 agctaactaa ggaaaatact gctgaataag cttagaaagc agaggggctt atggttggac
     3121 aagatattat tcatgaagcc atgagagcaa cttggacgat tgataaagtt ggcggagttt
     3181 tagctatagc tattatccta gtcatcttgc ttttaatcag tggtatgatt tgggtcatca
     3241 agaagttagt gactggcttt caggagacga ataaggaact gttagcttcc aataatcgga
     3301 ttgctactga aaaccaacag caaatggcta gattgacaga agctgttaat aatctctcac
     3361 tagaaactcg caaagacata tcagttttgc aagagaaagt ggacgattta gaagatgttg
     3421 ttagaaatac acagatgttt taaaggagta agaaaatgaa tgatgtaatt ttacaaggca
     3481 ttatgcttat tttaactggc tttgctggtt ttatcgtgaa aacagtaaag gactacctct
     3541 ttaaagaggg tggagaaaaa gctttgcgta ttgttgaaat cgtggcaaaa aatgctgtta
     3601 acgcagtgga gcagattgca aatgaggaca ctaaaggcga acaaaaatta aatgctgcta
     3661 agacgaaagt caagaaagcg ttagagcaat acaatatcta tttatctgat agtcagcttg
     3721 aaatgtttat tgaagcagca gtaaaagaaa tgaatgatag ctggaaagga gaaaataaat
     3781 gaatacagat gttttaatca actggtttga aagtcgtcga ggaaaactta cttattcgat
     3841 gtacggaagt cgtaacggct cagacggcac agcagactgt tcagggtcaa tctcccaagc
     3901 tttgaaagag gctggagtaa atatcatcgg tttaccgtca acggtgacat taggctcaca
     3961 attggcaaat aatggctttt atcgtgtatc aaaaaacgaa gattggaatg gtcaacgagg
     4021 cgacattgtc atgatgtcat ggggtgctga tatgtcacaa tctggtggtg ctggcggtca
     4081 tgttggtgta ctggaagatg ctaatacgtt catcagcgtt gactattcaa ctggcggaca
     4141 agcaggtaca gcagtgtcat ctcataattg ggatagttat tacaacaatt ctagaccagc
     4201 ttacgttgaa gcttggcgtt ttagcgggtc aacagctaca cagcctaaca cagttgtttc
     4261 aggcggtcgt aaaccagaca gcaaagctta ctatctagcc aatcaggtag ctttcgtaaa
     4321 tggcatttac caaattaaat gcgattacct agctccaatt ggattcaact gggttgccta
     4381 atttcagctc agtataaact atatgaacgc atacaaagcg gtgttatact atatgtatag
     4441 ctaacggtgg aactcccatg tggacaatac cgtgccaagc ctaataatgt aggaaggtgt
     4501 aacgactatc cctttgtgga gtacgtttac tatttgtacg taaatggaag tgtatagatt
     4561 ttagaagaaa ggtatcataa gatgagtaaa accaaacgtg gcgtttgtgc caactgtcat
     4621 aaagtttttg tagtatcaaa aaaacaagct gagcgcatga aacaaggaaa atctgtttat
     4681 tgctctatgg aatgtggatt agaaaagaac ggtaaaagcc gaatcgtggt ccacgatatt
     4741 ccttgttgta aatgcggagc actatttaca ccgacacgtc aacagtataa gcgctataaa
     4801 tacaacaata atgtatctat atcatactgt tctgatgaat gtcggtataa acgagattac
     4861 ccttttacac cacatgacga ttatgttact gtctatgtgg gtgatgatga agtgctatta
     4921 gattgggata tatttgaaga ttatggttgt acgatctaca taatatatga taaacgcaat
     4981 ggttataaaa acgtttcagt atttcaaaat ggacgtaaga aacgccttgc tagagatata
     5041 cttgacgtaa cagatcctaa tattgaaata gaccatatta acggtaacac gcttgacaat
     5101 cgtagaagta acttaagaat agtgacacac actgaaaata tgtggaataa agataactac
     5161 aaaaataata cttcaggtat aaaaggtgtt catttaaata aaaagggttt gtgggttgca
     5221 cgcatacaag taggtaaaga ccgattattc ttaggttctt ctaaagacaa atcagtcgct
     5281 gaaaaaatgc gtttagatgc agagaaaaaa tactttggaa aatatgacag gaagtttcta
     5341 aaataagata tagtctaatc ttattagcaa taataagtat tttatgtgaa aacggtatcc
     5401 cagtaggtct ggtcaattgg gttgatgaaa acggaaacaa cttgcctgac ggtcaagaca
     5461 aggactttaa agctggtatg tactttagtt ttgagattga cgaggctcat attgcagatg
     5521 ctggcgaagg cggatattat ggcggatatt actggcgtaa atttgagttc ggtcaattcg
     5581 gtacagtctg gctttcttgt cgtgataaag acgacttggt aaattattac aattaagcca
     5641 aaagaaaagc tctaagcgat tgcttagggc ttcttttttt atctataaaa taaataagcg
     5701 actagataca atgtcatttt taaaaatcgt caaaccaacg tatctcttgc cgactttaat
     5761 gatttttgtt agtttgatat cagctaaacc gtgtattcta aattctaatt taacaactgg
     5821 ataccatttt ccgcaaaatt ttccgtattt gaaaggattt ttcattttac tacctcgctc
     5881 gcttttgtta tattataaca taaatagtat aattaaatag ttaaccttta acgccttagc
     5941 ctttgtggtt aaggcttttt ttggtataat aggtacataa gtagttgaga ggtcttactt
     6001 ataatatctg gcagagagtg ggctgacgag cgcacgttaa agagaagtac gttttgggct
     6061 agcgtgagct agtccttttt ttattttcca aattacccca gcagcaccca gaaagcctat
     6121 aacagcaacg tttgtttatt ttccgtttta acggactttt tttattattt ccgttataac
     6181 ggactaaaaa attttaaaaa atatcaaaaa agttaaagaa agttattg
//
LOCUS       DATWEK010000063         5524 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.063, whole genome shotgun sequence.
ACCESSION   DATWEK010000063 DATWEK010000000
VERSION     DATWEK010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5524
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.063"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..1144
                     /locus_tag="VCR92_001735"
     CDS             <1..1144
                     /locus_tag="VCR92_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEP4268781.1"
                     /translation="DNKLTVDDESRDAPAGIAHFLEHKLFEDESGGDISLKFTQLGAE
                     TNAFTTFNQTSFFFSTASKFQENLELLQYFVLSANITDESVSREKKIIGQEIDMYQDD
                     ADYRAYSGILQNLFPKTSLANDIAGSKASIQKITKILLETHHTYFYQPTNMSLFIVGD
                     IDIDETFLAIQRFQTTLSYPDRKRVTVDPLHYYPVIKSSSVDMDVTIAKLVVGFRGYL
                     TLTQHSLLTYRIALKLFLSMLIGWTSKIYHTLYEDGKIDDSFDVDVEIHHHFQFVLIS
                     LDTPEPIAMSNYIRQKLATIKISKEFTNEHLNLLKKEMYGDFIQSLDSIEHLTHQFSL
                     YLSDSDKETYFDIPKIIERLTLKDVVTIGKAFFEKADASDFTVFPK"
     gene            1194..2219
                     /locus_tag="VCR92_001736"
     CDS             1194..2219
                     /locus_tag="VCR92_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP4268782.1"
                     /translation="MSEKSLGEVLRESRVGKNITLDDIELKTGISSHYLLAMELDQFK
                     IIPEEKFDQFLKEYADIVELDFNTLKRRYRYQVNSKKDSDIKSVTEIVEEKLSKKRLQ
                     EKLLSHQSMGYGQPLEVSKNKETLVIPVKTVGLDSKSPLKTISPVSQFKSDNRLIPKK
                     NVSRMRRNSTDSRSKTSLFPIAILGTVAFAIISVIILGVWQQFEKSQRAKEAEVALLK
                     ASEQSTNGLKNNSNDRKTQVTTEGSGNYLIATVTKSKETVDISVSLTEAQSSWISLTN
                     SEIGEGGITLTQDSPTYTATLPAEITESLLTLGVTKGVSVTIDGQPVDLSPLTSTDLS
                     YITFKIQ"
     gene            2233..2775
                     /gene="pgsA"
                     /locus_tag="VCR92_001737"
     CDS             2233..2775
                     /gene="pgsA"
                     /locus_tag="VCR92_001737"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEP4268783.1"
                     /translation="MIKKENIPNLLTLVRIAMIPFFLFITSSSNKVGWHIFAAVIFAI
                     ASFTDYLDGYLARKWHVASNFGKFADPLADKMLVMSAFIMLVGLGLVPAWVSAVIICR
                     ELAVTGLRLLLVETGGKVLAAAMPGKIKTATQMLSIILLLCHWIFLGNVLLYIALFFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            2777..3616
                     /locus_tag="VCR92_001738"
     CDS             2777..3616
                     /locus_tag="VCR92_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEP4268784.1"
                     /translation="MSAIIELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGS
                     GKSTTIRLIDGLLEPESGSIIVDGDLLTITNVWEIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGIAHEDIKERVNHALELVGMQNFKEKEPARLSGGQKQRVAIAGAVAMKPK
                     IIILDEATSMLDPKGRLELIKTIKNIRDDYQLTVISITHDLDEVALSDRVLVMKDGQV
                     ESTSTPEQLFARGDELLQLGLDIPFTTSVVQMLQEEGYPVDYGYLTEKELENQLCQLI
                     SKM"
     gene            3592..4434
                     /locus_tag="VCR92_001739"
     CDS             3592..4434
                     /locus_tag="VCR92_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEP4268785.1"
                     /translation="MSINLQNVSYTYQAGTPFEGRALFNINLDILDGSYTAFIGHTGS
                     GKSTIMQLLNGLHVPTTGIVSVDKQDITNHSKNKEIKSIRKHVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSPEEAEALAREKLALVGISENLFEKNPFELSGGQMRRVAIAGIL
                     AMQPKVLVLDEPTAGLDPKGRKELMTIFKKLHQSGMTIVLVTHLMDDVANYADFVYVL
                     DKGKIILSGKPKTIFQQVSLLEKKQLGVPKVTKLAQRLVDRGIPISSLPITLEELKEV
                     LKHG"
     gene            4427..5227
                     /locus_tag="VCR92_001740"
     CDS             4427..5227
                     /locus_tag="VCR92_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEP4268786.1"
                     /translation="MDKLILGRYIPGDSLIHRLDPRSKLLAMIIYIVIIFWANNVVTN
                     LLMLTFTLAVVFLSKIKLSFFLNGVKPMIGIILFTTLFQMFFSQGGKVIFSWWFISIT
                     DLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVESLLKPLTRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQRARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGEGRTKYRQLDWQLKDSLAIGIVSLLGLLLFFLKTSL"
BASE COUNT         1795 a          882 c         1022 g         1825 t
ORIGIN      
        1 tgacaataag ttgacagtcg atgacgaatc acgagatgct ccagcaggta ttgcacactt
       61 tttagaacat aaactctttg aagatgaatc aggtggagat atttcattaa agtttacaca
      121 gctaggagca gagacaaatg cctttacaac tttcaaccaa acgagtttct tcttttcaac
      181 agctagtaaa tttcaggaaa atttggaact ccttcaatat tttgttcttt ctgctaatat
      241 aacagatgaa tctgttagta gagaaaaaaa aataatcggg caagaaattg atatgtatca
      301 agatgatgct gactaccgtg catatagtgg aatccttcag aacttatttc caaaaacaag
      361 tttagctaat gatattgctg gctcaaaagc atccattcaa aagatcacga aaatattatt
      421 ggaaacgcat catacttatt tttaccaacc tactaatatg agtctattca ttgtcggtga
      481 tattgatatt gacgaaactt ttttagctat tcaaaggttt caaaccacat tatcctatcc
      541 agatagaaaa agggtaactg ttgatccttt acactactat cctgtcatta aatcatcttc
      601 tgttgacatg gatgttacta ttgccaagct ggttgttggt tttcgagggt atctgacctt
      661 aactcagcat tcactattaa cgtatcgtat tgccttgaag ctatttttat caatgcttat
      721 aggttggact tctaaaatct atcatacgct atatgaagat ggtaaaatag acgattcatt
      781 tgatgtggat gttgaaattc atcatcattt tcaatttgta ttaatatcac ttgatacacc
      841 agagcctatc gcaatgtcta actatatccg tcaaaaatta gccactataa agatatcaaa
      901 agagtttaca aatgagcact taaatctatt aaaaaaagaa atgtatggtg actttattca
      961 gagtttagac tctatagaac atttaaccca tcagttcagt ctatacctgt ctgattctga
     1021 taaagaaaca tattttgata ttccaaaaat tatagaaaga ctcactctaa aagatgttgt
     1081 tacaattgga aaagcatttt ttgaaaaagc tgatgcttca gacttcacag tcttcccaaa
     1141 atagatgaaa atctgttata ataggattac tatattattt ttgaggtacc tgtatgagtg
     1201 aaaaaagtct tggtgaagtg ttaagagaat cgcgtgttgg aaaaaatatc acactagatg
     1261 atatagaatt gaagacaggg atttcttccc attacttgct ggcaatggaa ttggatcagt
     1321 ttaaaattat tccggaagaa aaatttgatc aatttttaaa agaatatgct gacattgttg
     1381 agttagattt caatacttta aaaagacgat accgttatca agttaattcc aaaaaagaca
     1441 gtgatataaa atctgtaact gagattgttg aagagaagtt aagtaagaaa cgattacaag
     1501 agaagttgtt atcacatcag agcatggggt atggtcaacc gttagaagtt tctaaaaaca
     1561 aagaaacctt agttatccct gtaaagactg ttggtttaga tagcaaatcg ccactaaaaa
     1621 cgatatcgcc tgttagccaa tttaaatcag ataacaggtt aattcctaaa aaaaatgtgt
     1681 cacgtatgag gcgaaatagc actgacagtc gttctaaaac gtcactattt cccatagcta
     1741 tattaggaac ggttgctttt gcaattatca gtgttatcat tttaggtgtt tggcaacaat
     1801 tcgaaaagag tcaaagagct aaagaagctg aagttgcttt gcttaaagcc tctgagcagt
     1861 ctactaacgg tttaaaaaat aattcaaatg atcgcaaaac tcaagtcaca actgaggggt
     1921 cgggtaatta tttaatagcg actgttacta aatctaaaga gaccgttgat atcagtgtgt
     1981 ctttaactga ggcacaaagt agttggattt ctctaacaaa ttcagaaatt ggtgaaggtg
     2041 gtataacatt gactcaagac tcgccaactt atacagcgac tttacctgca gaaataacag
     2101 aatcattgtt gacacttggt gtgacaaaag gtgtatctgt aacaattgat ggacaacctg
     2161 ttgatctatc acctttaaca agtactgact taagttatat cacgtttaag atccaataat
     2221 taaggtagac taatgataaa aaaagaaaat attcctaatc tattaactct tgttcgaatc
     2281 gcaatgattc ctttctttct ttttattact tcctcatcta ataaggtggg gtggcatatt
     2341 tttgcagctg tgatttttgc aattgccagt tttaccgatt atctagatgg gtatcttgcg
     2401 cgtaagtggc atgtagccag taattttgga aagtttgccg atcctctagc agataagatg
     2461 cttgtcatga gtgcctttat catgttagtt ggacttggct tagttcctgc gtgggtgtca
     2521 gctgttatta tttgccgaga attggcagta actggtcttc gattactact tgttgaaacc
     2581 ggaggaaagg tccttgcagc tgctatgccg ggaaaaatca aaacagcgac acaaatgttg
     2641 tctattattt tattactttg ccattggata ttcctaggaa acgtcttact ctatattgct
     2701 ctttttttca ctatttattc tggatatgat tattttaaag gagcaagctt tctttttaag
     2761 gatacgttta aataacatgt cagctattat tgaacttaaa aaagttacat ttaattacca
     2821 taaagaccaa gaaaaaccaa cattagatgg cgtatcgttt catgtgaaac aaggtgagtg
     2881 gctgtctatc attggccata acggatctgg taaatcaacg actattcgat taattgatgg
     2941 attattggaa ccagaatcag ggtctattat tgttgatgga gatctactaa ccataactaa
     3001 tgtttgggaa attcgtcata aaattggtat ggtctttcaa aaccctgata atcagtttgt
     3061 tggagcaact gttgaagatg atgttgcttt tgggcttgaa aataaaggta ttgcacatga
     3121 agatataaaa gagagggtta atcatgcttt agagttagtc ggcatgcaga actttaaaga
     3181 aaaagaacca gcccgtttat ctggtggcca aaaacagcgc gtagctattg caggtgcagt
     3241 tgctatgaag cctaaaatta ttattttaga tgaagctact agtatgcttg accctaaagg
     3301 acgattagag ttaatcaaaa ctataaaaaa catccgtgac gactaccagc tgactgttat
     3361 ttccattact catgacttag atgaagttgc tcttagtgat agagttttag tgatgaaaga
     3421 tggtcaagtg gaatcaacat caacaccaga acaattattt gcaagagggg atgaactact
     3481 ccaattaggt cttgatatcc cttttacaac atctgttgta cagatgcttc aagaagaagg
     3541 ttatcctgtt gactatggat atctcacaga aaaggaatta gaaaatcagt tatgtcaatt
     3601 aatctccaaa atgtaagtta tacttatcaa gcagggactc cttttgaagg gcgtgccctt
     3661 tttaacatta atttagatat tttagatggt tcttatacgg cttttatcgg acatactgga
     3721 tccgggaaat cgaccattat gcaattgcta aatggtttac acgttccgac aacgggaatt
     3781 gtcagcgtag ataaacaaga tataacgaat cactctaaaa ataaagagat taaatctatt
     3841 cgaaaacatg taggattagt ttttcaattt ccagaaagtc aactatttga agagacagtt
     3901 ttgaaagatg ttgcttttgg ccctcaaaat tttggggtct ctccggagga agcagaagct
     3961 ttagcgcgtg aaaaactagc tcttgttggg atttcagaaa atctttttga aaagaatcca
     4021 tttgaactct cagggggtca aatgcgtcgt gttgctattg cgggtatcct tgctatgcag
     4081 ccaaaggttt tagttttaga tgaaccgact gctggtcttg atcctaaagg gcgtaaagaa
     4141 ttaatgacta tttttaaaaa gttacaccaa tctggcatga ctattgtttt agtaacccat
     4201 ctgatggatg atgtggccaa ttacgcagat tttgtatatg ttcttgacaa aggtaaaatt
     4261 attttatcag gaaaacccaa aacaattttt caacaagtca gtttgcttga gaaaaaacag
     4321 ttaggagttc ctaaggtgac taaacttgct caaaggcttg ttgatagagg aatacctatc
     4381 tcttctttgc ctattacctt agaggagcta aaagaggtac taaaacatgg ataagctgat
     4441 tcttggtcgt tatattcccg gagattctct cattcatcgt cttgacccaa gaagtaaatt
     4501 attagcgatg attatttata ttgtcattat cttttgggct aacaatgttg tgacaaattt
     4561 gttgatgttg acttttactt tagcagttgt ttttttgtca aaaatcaagt tgtctttctt
     4621 tttaaatggg gttaaaccaa tgattggtat tatcctcttc acgactttat ttcagatgtt
     4681 tttctcacaa ggaggaaaag taatttttag ttggtggttc attagcataa ctgatttagg
     4741 attgagccaa gctattttaa tttttatgcg tttcgttcta attattttct tttcaacgct
     4801 gttaacgttg acgacaacac ctttaagcct atctgatgca gttgaatcat tattaaaacc
     4861 tttaacaaga tttaaagttc cagctcacga gatcggacta atgctttctt taagtttacg
     4921 ttttgtgcct actttaatgg atgataccac gcgtattatg aatgcacaaa gggcccgtgg
     4981 agttgatttt ggagagggaa atttaattca aaaagttaaa tctattattc ctattttaat
     5041 ccctcttttc gcttcaagct ttaaaagagc cgacgcatta gctattgcta tggaagctag
     5101 aggttatcag ggaggagaag ggcgaactaa atatcgtcaa ttagactggc agctaaaaga
     5161 tagtttagct attggaatag tttctttatt gggtttgcta ctttttttct tgaaaacctc
     5221 tttgtaatat tttttagcac aaaacttttc tttattagta agaagtgaat tgtacctcaa
     5281 aagttagata caacatctaa tgattgaggt acttttcttc atttgaggaa ttgaaaaccg
     5341 ctatctcaac tatattaatc ctcccaataa taacaaatcg aacgaaatct aaaaggactg
     5401 agtcctgttc aatacagaac taaattatta gtttaatgat attatcccgc tttttaatgt
     5461 tgctaagaag aagagtttta tgatttttta caacttctta taatatcaat gtagttgtaa
     5521 tatt
//
LOCUS       DATWEK010000064         5156 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.064, whole genome shotgun sequence.
ACCESSION   DATWEK010000064 DATWEK010000000
VERSION     DATWEK010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5156
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.064"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            101..1649
                     /locus_tag="VCR92_001741"
     rRNA            101..1649
                     /locus_tag="VCR92_001741"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1701..1773
                     /locus_tag="VCR92_001742"
     tRNA            1701..1773
                     /locus_tag="VCR92_001742"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1734..1736,aa:Ala,seq:tgc)
     gene            2074..4976
                     /locus_tag="VCR92_001743"
     rRNA            2074..4976
                     /locus_tag="VCR92_001743"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5062..>5156
                     /gene="rrf"
                     /locus_tag="VCR92_001744"
     rRNA            5062..>5156
                     /gene="rrf"
                     /locus_tag="VCR92_001744"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1461 a         1063 c         1481 g         1151 t
ORIGIN      
        1 agacgaacca aacgtgaggg tgatatggag acatattacc cgtcaagaaa cgagaaataa
       61 atctgtcagc gacagaagga acgagtaagt tcaaacgcaa attaaagaga gtttgatcct
      121 ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct gagaactggt
      181 gcttgcaccg gttcaaggag ttgcgaacgg gtgagtaacg cgtaggtaac ctacctcata
      241 gcgggggata actattggaa acgatagcta ataccgcata agagagacta acgcatgtta
      301 gtaatttaaa aggggcaatt gctccactat gagatggacc tgcgttgtat tagctagttg
      361 gtgaggtaaa ggctcaccaa ggcgacgata catagccgac ctgagagggt gatcggccac
      421 actgggactg agacacggcc cagactccta cgggaggcag cagtagggaa tcttcggcaa
      481 tgggggcaac cctgaccgag caacgccgcg tgagtgaaga aggttttcgg atcgtaaagc
      541 tctgttgtta gagaagaatg atggtgggag tggaaaatcc accaagtgac ggtaactaac
      601 cagaaaggga cggctaacta cgtgccagca gccgcggtaa tacgtaggtc ccgagcgttg
      661 tccggattta ttgggcgtaa agcgagcgca ggcggttttt taagtctgaa gttaaaggca
      721 ttggctcaac caatgtacgc tttggaaact ggagaacttg agtgcagaag gggagagtgg
      781 aattccatgt gtagcggtga aatgcgtaga tatatggagg aacaccggtg gcgaaagcgg
      841 ctctctggtc tgtaactgac gctgaggctc gaaagcgtgg ggagcaaaca ggattagata
      901 ccctggtagt ccacgccgta aacgatgagt gctaggtgtt aggccctttc cggggcttag
      961 tgccggagct aacgcattaa gcactccgcc tggggagtac gaccgcaagg ttgaaactca
     1021 aaggaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg
     1081 aagaacctta ccaggtcttg acatcccgat gcccgctcta gagatagagt tttacttcgg
     1141 tacatcggtg acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa
     1201 gtcccgcaac gagcgcaacc cctattgtta gttgccatca ttaagttggg cactctagcg
     1261 agactgccgg taataaaccg gaggaaggtg gggatgacgt caaatcatca tgccccttat
     1321 gacctgggct acacacgtgc tacaatggtt ggtacaacga gtcgcaagcc ggtgacggca
     1381 agctaatctc ttaaagccaa tctcagttcg gattgtaggc tgcaactcgc ctacatgaag
     1441 tcggaatcgc tagtaatcgc ggatcagcac gccgcggtga atacgttccc gggccttgta
     1501 cacaccgccc gtcacaccac gagagtttgt aacacccgaa gtcggtgagg taacctatta
     1561 ggagccagcc gcctaaggtg ggatagatga ttggggtgaa gtcgtaacaa ggtagccgta
     1621 tcggaaggtg cggctggatc acctcctttc taaggaaatg gaacacgttt atcgtcttat
     1681 ttagttttga gaggtcttgt ggggccttag ctcagctggg agagcgcctg ctttgcacgc
     1741 aggaggtcag cggttcgatc ccgctaggct ccatcaggat acaatcctac taaacttaat
     1801 acaagtgaag ttgaacacgc aactcacttc ctaggaaaat agacaatctt cccttgtgtg
     1861 caaggcccac atggtcagat tcctaatttt ctacagaagt ttcgctaaag cgagcgttgc
     1921 ttggtatcct atataatagt ccattgaaaa ttgaatatct atatcaaatt ccacgatcta
     1981 gaaatagatt gtagaaaagt aacaagaaaa taaaccgaaa acgctgtgac tatttgataa
     2041 gttttctagt ttttaaaaaa actaggttaa taaggttaag ttaataaggg cgcacggtgg
     2101 atgccttggc actagaagcc gaagaaggac gtgacaaacg acgaaatgct ttggggagct
     2161 gtaagtaagc gctgatccag agatgtccga atgggggaac ccactaacta atggttagta
     2221 tccataactg ttaaggttat gagaaggaag acgcagtgaa ctgaaacatc taagtagctg
     2281 caggaagaga aagcaaacgc gattgcctta gtagcggcga gcgaaacggc aggagggcaa
     2341 accgaagtgt ttacacttcg gggttgtagg actgcgacgt gggactttaa aaggatagaa
     2401 gaattacctg ggaaggtaag ccaaagagag taaaagcctc gtatttaaaa ttcttttgag
     2461 ccctagcagt atcctgagta cggcgagaca cgtgaaatct cgttggaatc tgggaggacc
     2521 atctcccaac cctaaatact ctctagtgac cgatagtgaa ccagtaccgt gagggaaagg
     2581 tgaaaagcac cccgggaggg gagtgaaata gaacctgaaa ccgtgtgcct acaacaagtt
     2641 cgagcccgtt aatgggtgag agcgtgcctt ttgtagaatg aaccggcgag ttacgatatg
     2701 atgcgaggtt aagttgaaga gacggagccg tagggaaacc gagtcttaat agggcgattt
     2761 agtatcatgt tgtagacccg aaaccatgtg acctacccat gagcaggttg aaggtgaggt
     2821 aaaactcact ggaggaccga accagggcac gttgaaaagt gcttggatga cttgtgggta
     2881 gcggagaaat tccaaacgaa cttggagata gctggttctc tccgaaatag ctttagggct
     2941 agcgtcgatg ttaagtctct tggaggtaga gcactgtttg ggtgaggggt ccatctcgga
     3001 ttaccaatct cagataaact ccgaatgcca acgagatatc atcggcagtc agactgcgag
     3061 tgctaagatc cgtagtcgaa agggaaacag cccagaccac cagctaaggt cccaaaataa
     3121 ctgttaagtg gaaaaggatg tggggttgca cagacaacta ggatgttagc ttagaagcag
     3181 ctattcattc aaagagtgcg taatagctca ctagtcgagt gaccctgcgc cgaaaatgta
     3241 ccggggctaa aacagtttac cgaagctgtg gatgacacaa aagtgtcatg gtaggagagc
     3301 gttctatgtg tgaagaaggt gtaccgtgag gagcgctgga acgcatagaa gtgagaatgc
     3361 cggtatgagt agcgaaagac aggtgagaat cctgtccacc gtaagactaa ggtttccagg
     3421 ggaaggctcg tccgccctgg gttagtcggg acctaaggag agaccgaaag gtgtatccga
     3481 tggccaacag gttgatattc ctgtactaga gtatatagtg atggagggac gcagtaggct
     3541 aactaaaccg gacgattgga agagtccggc taagcagtga ggtgtaagat gagtcaaatg
     3601 cttatcttta taacattgag ctgtgatggg gagcgaattt tagtagcgaa gttagtgatg
     3661 tcacactgcc aagaaaagct tctagcgttt aatgatactc tacccgtacc gcaaaccgac
     3721 acaggtagtc gaggcgagta gcctcaggtg atcgagagaa ctctcgttaa ggaactcggc
     3781 aaaatgaccc cgtaacttcg ggagaagggg tgctgactta ggtcagccgc agtgaatagg
     3841 cccaagcaac tgtttatcaa aaacacagct ctctgctaaa tcgtaagatg atgtataggg
     3901 ggtgacgcct gcccggtgct ggaaggttaa gaggagggtt tagcgcaagc gaagatctga
     3961 attgaagccc cagtaaacgg cggccgtaac tataacggtc ctaaggtagc gaaattcctt
     4021 gtcgggtaag ttccgacccg cacgaaaggc gtaatgattt gggcactgtc tcaacgagag
     4081 actcggtgaa attttagtac ctgtgaagat gcaggttacc cgcgacagga cggaaagacc
     4141 ccatggagct ttactgcagt ttgatattga gtatctgtac cacatgtaca ggataggtag
     4201 gagccattga cttcgggacg ccagtttcga atgaggcgct gttgggatac tacccttgtg
     4261 ttatggctac tctaacccag ataggttatc cctatcggag acagtgtctg acgggcagtt
     4321 tgactggggc ggtcgcctcc taaagagtaa cggaggcgcc caaaggttcc ctcagattgg
     4381 ttggaaatca atcgcagagt gtaaaggtat aagggagctt gactgcgaga gctacaactc
     4441 gagcagggac gaaagtcggg cttagtgatc cggtggtacc gaatggaagg gccatcgctc
     4501 aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtt cacatcgacg
     4561 gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg ggctgtagtc ggtcccaagg
     4621 gttgggctgt tcgcccatta aagcggcacg cgagctgggt tcagaacgtc gtgagacagt
     4681 tcggtcccta tccgtcgcgg gcgtaggaaa tttgagagga tctgctccta gtacgagagg
     4741 accagagtgg acttaccgct ggtgtaccag ttgtcttgcc aaaggcatcg ctgggtagct
     4801 atgtagggaa gggataagcg ctgaaagcat ctaagtgcga agcccccctc aagatgagat
     4861 ttcccatgat tttatatcag taagagccct gagagatgat caggtagata ggttaggagt
     4921 gtaagtgtag cgatacatgt agcggactaa tactaatagc tcgaggactt atccaaaaag
     4981 aaatattgac aacgttacgg attcttgtta gactatagat attcaatttt gagtgggtta
     5041 tgaaaatagc acatttacaa gttaagtgac gatagcctag gagatacacc tgtacccatg
     5101 ccgaacacag cagttaagcc ctagaacgcc tgatgtagtt gggggttgcc ccctgt
//
LOCUS       DATWEK010000065         5154 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.065, whole genome shotgun sequence.
ACCESSION   DATWEK010000065 DATWEK010000000
VERSION     DATWEK010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5154
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.065"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(85..618)
                     /locus_tag="VCR92_001745"
     CDS             complement(85..618)
                     /locus_tag="VCR92_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEP4268787.1"
                     /translation="MVNRKENTKQAILKAMVMLLKTESFDDITTVKLSKRAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKKYQNKEQAFLEVFEFLQREQLLSSLLSANG
                     TKEIQAFIINKVRLLITTDLQDKFSTEELSQTEKEYQSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTQFVLKMLTST"
     gene            753..3026
                     /locus_tag="VCR92_001746"
     CDS             753..3026
                     /locus_tag="VCR92_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEP4268788.1"
                     /translation="MLEELKTLIKNPKLMITMIGVALVPALYNLSFLGSMWDPYGRVN
                     DLPIAVVNHDKPAKRADKSLTIGNDMVDKMSKSKDLEYHFVSAKQAQEGLKEGDYYMV
                     ITLPEDLSQRAATLLNPEPQKLTIRYQTSKGHGMVAAKMGETAMAKLKESVSQNITKT
                     YTSAVFSSMTDLQSGLKEASAGSQALASGAKTAQAGSQTLSTNLAALTGASQQFQQGT
                     GRLTSGLTTYTDGVNQVKNGLGTLSTDIPNYLNGVSRLSQGASQLNQGLSQLTQATTL
                     SDEKAKGIQSLIVGLPVLNQGIQQLNTELSTLQPPNLNADELGNSLGAIAQAAKQVIA
                     EETAAQNEQLSALQATSVYQSLTAEQQGELAAALSQSDKSQTVSAAQTILSSVQTLST
                     GLQTLSQGNSLAQLDQLKAAVSQIASQSNQALPGASSALSELSMGLSKVNGSLNQQVL
                     PGSNQLTTGLAQLNRYNTVIGSGVIKLSEGANALSSKSGELLDGSHQLSEGATKLADS
                     SSQLSQGGHQLTSGLTELSTGLSTLNGSLAKASQQLSLVSVTDKNAKAVAKPLVLNEK
                     DKDGVKTNGIGMAPYMIAVSLMVVALSTNVIFANSLSGRPVKDKWDWAKQKFVINGFI
                     STMGSIVLYLAIQLLGFEARYGMETLGFIMLSGWTFMALVTALVGWDDRYGSFASLVM
                     LLLQVGSSGGSYPIELSGAFFQKLHPFLPMTYVVSGLRQTISLSGHIGVEVKVLTGFL
                     LAFMVLALLIYRPKKTV"
     gene            complement(3143..4216)
                     /locus_tag="VCR92_001747"
     CDS             complement(3143..4216)
                     /locus_tag="VCR92_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEP4268789.1"
                     /translation="MKNISRKCFMTSVVCIVLGAILLGAGYATGGLQDIKHQTAPKKV
                     IQTFDHVTALDIDTNFSTITVETGPVKKPTVTYYTHSKFIDPLEIKIENETLHISEKP
                     RDVIITGGIELIGFGLNKSDRNHNYRTTTITLPKGTSLKELKGSSMPQATISDLTVQD
                     LEFSGGLTLLNTRIKKGKVFGTFNATDSLLANLELKADYSLSSLTNSSLENGTISLGH
                     GQLTTKNTNLKSVTIQSLSPGGVETEETSLENVTFTVTSEQENEETNDNGAIFTAHAL
                     TLKGTNTISGGNVAVDITLTDPKTTAYKTKTEDGKILLGSQLTPAKIGKESTSDVISY
                     VAENKAATGNLTVNLNKGDITIK"
     gene            complement(4213..4800)
                     /locus_tag="VCR92_001748"
     CDS             complement(4213..4800)
                     /locus_tag="VCR92_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEP4268790.1"
                     /translation="MTRTEYLAELDKYLRKLPREDYHEALEYYIEYFDEAGPDKESQV
                     IDDLGNPKEAASEIISNVLGKHLATPEKTPKNRATIIGLTILSLFAAPIALPVLLALI
                     LFIIACLMLGLTAIFAAYIFGLAGILVAGVTLFESLTLIGSSIPAQAMGIGSALLCFG
                     GGLLIWIIATALLRFSGRAFVAFIKWISHKKGAQA"
     gene            complement(4787..5113)
                     /locus_tag="VCR92_001749"
     CDS             complement(4787..5113)
                     /locus_tag="VCR92_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEP4268791.1"
                     /translation="MYFPVSATLIEFLILAIVEKNDSYGYDISQTIKLVANIKESTLY
                     PILKKLEKAGFLTTYSQEHQGRKRKYYAVTSSGRAQLIFLKKEWQSYKFALDGIIEGS
                     LRHDKD"
BASE COUNT         1536 a          965 c         1011 g         1642 t
ORIGIN      
        1 atcccttcat tttactatgg cttctaaaaa agttatcact aaggctgatg acttgtaaaa
       61 tgatactttc gtaagggtta ttatttaggt actcgtaagc attttgagaa cgaattgtgt
      121 catttcttga ggtgattctt ttttaccttt agcaatccaa ctttgacaga caccaaaaaa
      181 agcatgggct aagtagatac tttggtattc tttttccgtt tgagataact cttcggtact
      241 gaacttgtcc tgtaaatcag tagtgatgag taggcgaact ttattgatga taaaggcctg
      301 tatttcttta gtaccgttag cagacaaaag ggaagagaga agctgttctc tttggagaaa
      361 ttcaaatact tcaaggaagg cttgttcttt attttgatat tttttctcaa aaatatattc
      421 taatttgtga aaaaaggttt gctgataata gtcaatcatt tcatatttat ctttatagtg
      481 tgtgtaaaaa ctagagcgac taattccagc tcttttagat aatttaactg tggtaatatc
      541 gtcaaaactt tcggttttta gtaacataac cattgctttt aaaattgctt gcttcgtatt
      601 ttctttacgg ttgaccatct accatctctc cttttgaaca cttttagacg taatgtccaa
      661 aagtgaattt ttttctcttg taaatttaaa tttaaattgt ataatatatt ttatcataat
      721 ttttgaacag tatgtccatt ttaggagaaa atatgttaga agaattgaaa acacttatta
      781 aaaatccaaa attaatgatt acaatgattg gtgtggccct agtgcctgcc ttatataatt
      841 tatcctttct aggctcaatg tgggatcctt atggtcgggt caatgacctt cccattgctg
      901 ttgttaatca tgataagcct gcaaagagag ctgataagtc attgacaatt gggaatgata
      961 tggtggacaa gatgtctaaa agtaaagatt tagagtatca ttttgtctca gctaagcaag
     1021 ctcaagaggg acttaaagaa ggtgattatt atatggttat tactttaccc gaagatcttt
     1081 ctcaacgggc agcaacctta ttaaatcccg aaccccaaaa attaactatc cgttaccaaa
     1141 cgagtaaagg acatggaatg gtcgctgcta agatggggga aacagcgatg gctaagctga
     1201 aagagtctgt ttcgcaaaac attacgaaga cttatacctc agcagttttt agcagtatga
     1261 cagacctcca atcaggatta aaagaagcct cagctggaag tcaagcactt gcttcaggag
     1321 cgaagaccgc tcaggcgggg agtcaaacac tttcgacgaa cttagcagcc ttaacgggtg
     1381 ctagccaaca gtttcaacaa ggtactggtc gattgacatc aggtttgact acctatacag
     1441 atggtgtcaa ccaagtcaag aatgggttag gaacattatc aacggacatc cccaattatc
     1501 tgaacggggt ttctaggtta tcccagggag cttctcagct taatcagggt ctttcacagt
     1561 tgacacaagc aacaacactt tctgacgaga aagctaaggg aattcaatcc ttaattgtag
     1621 gactaccagt cctaaatcaa ggcattcagc aactaaatac agagctatca acattgcaac
     1681 cccctaacct taatgctgat gagttaggta atagcttagg agctatcgct caagctgcca
     1741 aacaagttat tgctgaagag actgccgctc agaatgaaca actatcggct ctccaagcca
     1801 ctagtgttta tcaatcatta actgctgaac aacaaggaga gttagctgcg gccctcagtc
     1861 aatctgataa aagtcaaacc gtatctgcag cccaaactat tttaagttct gttcaaacac
     1921 tgtcaacagg tttacaaact ctgtcccaag gaaatagttt agctcaatta gaccagctta
     1981 aagcagctgt ttcacagatt gcgagtcagt ctaaccaggc tttacctgga gcgagttctg
     2041 cattatctga gttgtcaatg gggttatcaa aggtaaatgg tagcttaaat caacaagttc
     2101 taccaggaag taatcaattg acaacaggat tagcacaatt aaacaggtat aatactgtca
     2161 ttggttctgg ggtaataaaa ctctcagaag gtgccaatgc cttgtcatcc aagtccggag
     2221 aattactaga tggtagccat caattatcag agggtgctac taaactagct gatagtagtt
     2281 ctcaattgag tcagggtggt catcaattaa cgagcggatt gactgaatta tcaacaggat
     2341 tatcaacctt aaatggttcc ttagccaaag cctctcagca gttatcgctt gtttctgtga
     2401 ctgataaaaa tgctaaagct gtcgcaaaac ctcttgtgtt aaatgagaaa gacaaagatg
     2461 gtgttaagac gaatgggatc gggatggcac cttatatgat tgctgtttct ctaatggttg
     2521 tggccctttc aaccaacgtc atttttgcta attctttatc tggtcgtccg gtcaaagata
     2581 aatgggattg ggctaaacaa aaatttgtta ttaatggttt tatttcgact atgggatcca
     2641 ttgttctcta cttagctatt caattattag ggtttgaagc ccgttatggt atggaaacct
     2701 taggatttat tatgctaagt ggttggacgt ttatggctct tgtcacagct ttggtcggtt
     2761 gggatgatcg atatggctct tttgcttctt tggtcatgtt attacttcag gttggctctt
     2821 caggtggctc ttaccccatt gagttaagtg gagcattctt ccaaaagtta catcctttct
     2881 taccaatgac ttatgtggta tctggtttac gacaaaccat ttcattatca ggtcatattg
     2941 gagtagaagt gaaagtctta actggtttct tactggcatt tatggtatta gcactactca
     3001 tttatcgtcc caagaaaaca gtctaaataa aataacctca aaaaaaaaca gcatctaagg
     3061 cagttacact agatgctgtt ttttgtctta ttttgacaat aacttgacaa tttctgtcaa
     3121 gttttttatt gtcttgttaa gattatttga tagtaatgtc tcccttattg agattaaccg
     3181 ttaaatttcc agtagctgct ttattctcag ccacataaga aataacatct gaagttgatt
     3241 ccttaccaat cttagctggt gtcagctgtg atccaagtaa gattttacca tcttcggttt
     3301 ttgtcttata ggcggtcgtc tttggatcgg tcaaagttat gtcaacagca acattaccac
     3361 cactaatagt attagtgcct ttaagggtaa gagcatgagc agtgaatata gcaccattat
     3421 cattggtttc ctcgttttct tgctcactag taacagtgaa agtcacattt tcaaggcttg
     3481 tttcttcagt ttcaacccca ccaggagata gagattggat ggtgacagat ttaagattag
     3541 tattttttgt ggttaattgt ccatgcccta agctaatcgt cccattttct aaactagaat
     3601 tcgtaaggct tgacaacgaa tagtcggctt tcaactcaag attggctaac aagctatcag
     3661 tagcgttaaa tgttccaaaa accttccctt tctttattct agtatttaga agtgtcagac
     3721 caccactgaa ctcaaggtct tgaaccgtta aatccgatat agtggcttga ggcatgcttg
     3781 agcctttgag ctctttaaga ctggtacctt ttggaagcgt tatggtagtg gttcggtagt
     3841 tgtggttgcg gtcactttta tttaatccaa acccgatcag ttcaatacct ccggtgatga
     3901 tgacatctct gggtttttca gaaatatgaa gtgtctcgtt ctctatttta atttctaaag
     3961 gatcaataaa tttagaatgt gtgtaatagg taacggttgg ttttttgaca ggccctgttt
     4021 ctactgtaat agttgaaaaa ttggtatcaa tatcaagagc tgttacgtga tcaaatgttt
     4081 ggataacctt tttaggggct gtttggtgtt taatgtcttg aagcccgcca gttgcataac
     4141 cagctcctaa aagaatggct cctaaaacaa tacacacgac actggtcata aaacatttgc
     4201 gtgagatatt tttcatgctt gagctccttt cttgtgacta atccatttaa taaaggcaac
     4261 gaaggcacgt cctgaaaaac gcaggagtgc agtggcaata atccaaatga gaagaccacc
     4321 accaaaacac aacaaggcgc tgccgattcc catagcttgt gcaggaatag atgagccaat
     4381 caaggtcaag ctttcaaaca gggtcactcc tgcgacaaga atacctgcaa gcccaaaaat
     4441 gtaggcggca aagatagctg tgagcccgag cattaggcag gcaataataa agagaatcaa
     4501 cgccagcaat acgggtaaag caatcggagc agcaaagagg gacaaaatgg ttaatccaat
     4561 aattgttgcc cgatttttgg gagttttctc gggagttgcc aagtgttttc ctagaacatt
     4621 tgaaatgatt tcactggcag cttccttagg atttcctaaa tcgtcgataa cctggctttc
     4681 tttgtcagga ccagcttcat caaaatattc aatataatat tccaacgctt catggtagtc
     4741 ttctctaggt agtttgcgca agtatttatc tagttctgct agatactcag tccttgtcat
     4801 gtcttaagct cccttcaata atcccgtcta aggcaaattt atagctctgc cattcttttt
     4861 ttagaaaaat cagctgtgct ctccccgaag aagtgacagc ataatattta cgctttcgtc
     4921 cctgatgttc ttgactataa gttgtcaaaa aacctgcctt ctccaatttt ttaagaatag
     4981 gatagagggt ggattctttg atattagcca ctagtttaat ggtttgacta atatcgtaac
     5041 cgtaagaatc gtttttttcg acaatggcta aaatcagaaa ttcaatcaag gtagccgata
     5101 ctggaaaata cattttaggc tcctttcata tataaaaatt ttatatataa ttat
//
LOCUS       DATWEK010000066         5058 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.066, whole genome shotgun sequence.
ACCESSION   DATWEK010000066 DATWEK010000000
VERSION     DATWEK010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5058
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.066"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            530..3556
                     /locus_tag="VCR92_001750"
     CDS             530..3556
                     /locus_tag="VCR92_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HEP4268792.1"
                     /translation="MKKHLKTVALTLTTVSVVTHNQEVFSLVKEPILKQTQASSSISG
                     ADYAESSGKSKLKINETSGPVDDTVTDLFSDKRTTPEKIKDNLAKGPREQELKAVTEN
                     TESEKQITSGSQLEQSKESLSLNKTVPSTSNWEICDFITKGNTLVGLSKSGVEKLSQT
                     DHLVLPSQAADGTQLIQVASFAFTPDKKTAIAEYTSRAGENGEISQLDVDGKEIINEG
                     EVFNSYLLKKVTIPTGYKHIGQDAFVDNKNIAEVNLPESLETISDYAFAHLALKQIDL
                     PDNLKAIGELAFFDNQITGKLSLPRQLMRLAERAFKSNHIKTIEFRGNSLKVIGEASF
                     QDNDLSQLMLPDGLEKIESEAFTGNPGDDHYNNRVVLWTKSGKNPYGLATENTYVNPD
                     KSLWQESPEIDYTKWLEEDFTYQKNSVTGFSNKGLQKVKRNKNLEIPKQHNGVTITEI
                     GDNAFRNVDFQNKTLRKYDLEEVKLPSTIRKIGAFAFQSNNLKSFEASDDLEEIKEGA
                     FMNNRIETLELKDKLVTIGDAAFHINHIYAIVLPESVQEIGRSAFRQNGANNLIFMGS
                     KVKTIGEMAFLSNRLEHLDLSEQKQLTEIPVQAFSDNALKEVLLPASLKTIREEAFKK
                     NHLKQLEVASALSHIAFNALDDNDGDEQFDNKVVVKTHHNSYALADGEHFIVDPDKLS
                     STMVDLEKILKLIEGLDYSTLRQTTQTQFRDMTTAGKALLSKSNLRQGEKQKFLQEAQ
                     FFLGRVDLDKAIAKAEKALVTKKATKNGQLLERSINRAVLAYNNSAIKKANVKRLEKE
                     LDLLTGLVEGKGPLAQATMVQGVYLLKTPLPLPEYYIGLNVYFDKSGKLIYALDMSDT
                     IGEGQKDAYGNPILNVDEDNEGYHALAVATLADYEGLDIKTILNSKLSQLTSIRQVPT
                     AAYHRAGIFQAIQNAAAEAEQLLPKPGTHSEKSSSSESANSKDRGLQSNPKTNRGRHS
                     AILPRTGSKGSFVYGILGYTSVALLSLITAIKKKKY"
     gene            3576..3977
                     /locus_tag="VCR92_001751"
     CDS             3576..3977
                     /locus_tag="VCR92_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEP4268793.1"
                     /translation="MITQEMKDLINNQLAMVATVDAKGQPNIGPKRSMRLWDDKTFIY
                     NENTDGQTRINIEDNGKIEIAFVDRERLLGYRFVGTAEIQTEGAYYEAAKKWAQGRMG
                     VPKAVGIIHVERIFNLQSGANAGKEINSESN"
     gene            complement(4167..5042)
                     /locus_tag="VCR92_001752"
     CDS             complement(4167..5042)
                     /locus_tag="VCR92_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEP4268794.1"
                     /translation="MPASKKVTIIFILNLSFSLIEFIFGTLFFSGAILADAVHDFGDA
                     IAIGISAILERKAVKKESPNFSLGYKRFSLLGALTTNLILISGSLLVMIETIPKLWHP
                     TIVNYDGMFVLAIFAIIINGFASFIIHSNQTKNEEILSLHFLEDILGWLAIIILSLIL
                     KWKPWYILDPLLSIAIASFILSKALPKLVATANIFLDGVPDSIDYCALHHELSQLPHI
                     VSVNQLNVWSMDGIDHRATIHCCLKESTTEKHCKKSIRLICQRYNINSVTVEIDTSLN
                     EHQHHCSSLSGIEVN"
BASE COUNT         1789 a          786 c          965 g         1518 t
ORIGIN      
        1 ttgaaaggag aaatagttta tgttagtata ctgattaagt gaagctgtaa tgaggcttat
       61 acgatcaaaa aagttagagt aactttataa aacagtggtg ttgaagcaag tttagcttct
      121 tctcagaaat agattatcta taaaaaatcc caaaagtagt ttgtttccag ttaatgaact
      181 tcttttggga aggctttttt gctgatcgcc acttcacttg tatatcggga acattcacgc
      241 taagatgtat aagttgaatc gtttgtctat ggcttgatga aaattaatca aaagataatg
      301 ttcaactcta taattagtac aagcaaaatg agataactta ttcattagta agcataagat
      361 ataacaagag aaattacctt aaaacaggaa gtactagagt atttaaaata agtgatagac
      421 ttggatatta ttaggtcgac tagtgttctt ttcaataatt taatatcgtt attattagta
      481 tcagccaatc aaatgtggat aagttggctt ttagaaaggt tttaccacaa tgaagaaaca
      541 tcttaaaaca gttgccttga ccctcactac agtatcggta gtcacccaca atcaggaagt
      601 ttttagttta gtcaaagagc cgattcttaa acaaactcaa gcttcttcat cgatttctgg
      661 cgctgactac gcagaaagta gcggtaaaag caagttaaag attaatgaaa cttctggccc
      721 tgttgatgat acagtcactg acttattttc ggataaacgt actactcctg aaaaaataaa
      781 agataatctt gctaaaggtc cgagagaaca agagttaaag gcagtaacag agaatacaga
      841 atcagaaaag cagatcactt ctggatctca actagaacaa tcaaaagagt ctctttcttt
      901 aaataaaaca gtgccatcaa cgtctaattg ggagatttgt gattttatta ctaaggggaa
      961 tacccttgtt ggtctttcaa aatcaggtgt tgaaaagtta tctcaaactg atcatctcgt
     1021 attgcctagt caagcagcag atggaactca attgatacaa gtagctagtt ttgcttttac
     1081 tccagataaa aagacggcaa ttgcagaata taccagtagg gctggagaaa atggggaaat
     1141 aagccaacta gatgtggatg gaaaagaaat tattaacgaa ggtgaggttt ttaattctta
     1201 tctactaaag aaggtaacaa tcccaactgg ttataaacat attggtcaag atgcttttgt
     1261 ggacaataag aatattgctg aggttaatct tcctgaaagc ctcgagacta tttctgacta
     1321 tgcttttgct cacctagctt tgaaacagat cgatttgcca gataatttaa aagcgattgg
     1381 agaattagct ttttttgata atcaaattac aggtaaactt tctttgccac gtcagttaat
     1441 gcgattagca gaacgtgctt ttaaatcaaa ccatatcaaa acaattgagt ttagaggaaa
     1501 tagtctaaaa gtgatagggg aagctagttt tcaagataat gatctgagtc aactaatgct
     1561 acctgacggt cttgaaaaaa tagaatcaga agcttttaca ggaaatccag gagatgatca
     1621 ctacaataac cgtgttgttt tgtggacaaa atctggaaaa aatccttatg gtcttgctac
     1681 tgaaaatacc tatgttaatc ctgataagtc actatggcag gaaagtcctg agattgatta
     1741 tactaaatgg ttagaggaag attttaccta tcaaaaaaat agtgttacag gtttttcaaa
     1801 taaaggctta caaaaagtaa aacgtaataa aaacttagaa attccaaaac agcacaatgg
     1861 tgttactatt actgaaattg gtgataatgc ttttcgcaat gttgattttc aaaataaaac
     1921 tttacgtaaa tatgatttgg aagaagtaaa gcttccctca actattcgga aaataggtgc
     1981 ttttgctttt caatctaata acttgaaatc ttttgaagca agtgacgatt tagaagagat
     2041 taaagaggga gcctttatga ataatcgtat tgaaaccttg gaattaaaag ataaattagt
     2101 tactattggt gatgcggctt tccatattaa tcatatttat gccattgttc ttccagaatc
     2161 tgtacaagaa atagggcgtt cagcatttcg gcaaaatggt gcaaataatc ttatttttat
     2221 gggaagtaag gttaagacca taggtgagat ggcattttta tcaaatagac ttgaacatct
     2281 ggatctttct gagcaaaaac agttaacaga gattcctgtt caagcctttt cagacaatgc
     2341 cttgaaagaa gtattattac cagcatcact gaaaacgatt cgagaagaag ccttcaaaaa
     2401 gaatcattta aaacaactgg aagtggcatc tgccttgtcc catattgctt ttaatgcttt
     2461 agatgataat gatggtgatg aacaatttga caataaagtg gttgttaaaa cgcatcataa
     2521 ttcctacgca ctagcagatg gtgagcattt tatcgttgat ccagataagt tatcttctac
     2581 aatggtagac cttgaaaaga ttttaaaact aatcgaaggt ttagattatt ctacattacg
     2641 tcagactact caaactcagt ttagagacat gactactgca ggtaaagcgt tgttgtcaaa
     2701 atctaacctc cgacaaggag aaaaacaaaa attccttcaa gaagcacaat ttttccttgg
     2761 ccgcgttgat ttggataaag ccatagctaa agctgagaag gctttagtga ccaagaaggc
     2821 aacaaagaat ggtcagttgc ttgaaagaag tattaacaga gcggtattag cttataataa
     2881 tagcgctatt aaaaaagcta atgttaagcg cttggaaaaa gagttagact tgctaacagg
     2941 attagttgag ggaaaaggac cattagcgca agctacaatg gtacaaggag tttatttatt
     3001 aaagacgcct ttgccattgc cagagtatta tatcggattg aacgtttatt ttgacaagtc
     3061 tggaaaattg atttatgcac ttgatatgag tgatactatt ggcgagggac aaaaagacgc
     3121 ttatggtaat cctatattaa atgttgacga ggataatgaa ggttatcatg ccttggcagt
     3181 tgccacttta gctgattatg aggggctcga catcaaaaca attttaaata gtaagcttag
     3241 tcaattaaca tctattcgtc aggtaccgac tgcagcctat catagagccg gtattttcca
     3301 agctatccaa aatgcagcgg cagaagcaga gcagttattg cctaaaccag gtacgcactc
     3361 tgagaaatca agctcaagtg aatctgctaa ctctaaagat agaggattgc aatcaaaccc
     3421 aaaaacgaat agaggacgac actctgcaat attgcctagg acagggtcaa aaggcagctt
     3481 tgtctatgga atcttaggtt acactagcgt tgctttactg tcactaataa ctgctataaa
     3541 aaagaaaaaa tattaaattg atttaaggag aagaaatgat aacacaagaa atgaaagatc
     3601 ttattaataa ccaattagca atggttgcga cggttgatgc caaaggtcaa cccaatattg
     3661 gtccaaaacg ttctatgcgt ctctgggatg ataaaacatt tatttataat gaaaatacag
     3721 atggtcaaac tcgtattaac attgaagata atgggaaaat tgaaattgcc tttgttgatc
     3781 gtgagcgcct tttaggttac aggtttgtag gaactgctga aattcaaaca gaaggtgctt
     3841 attacgaagc agcgaaaaaa tgggcacaag gacgcatggg ggtaccaaaa gcagttggta
     3901 ttattcatgt cgagcgtatt tttaatttac aatctggtgc taatgcaggt aaagaaataa
     3961 acagtgaaag taactaaaat taactaaaat taactgtaac agtatttagg acccttattt
     4021 taaatgctaa aaaacaagca tactcttttt tacagcatag tgactatgtt gtaaaaaggg
     4081 gtatgcttat taggtgctct taatatttct agataactgc acctaataag ttttcaatag
     4141 acttatagca cattagttga cttcaattag ttgacttcaa taccagaaag agaagaacag
     4201 tgatgttggt gttcgtttaa agaagtatcg atttccacag tgactgagtt tatattgtac
     4261 ctttgacaaa tcagtctaat agattttttg caatgttttt cagtggtaga ttctttcaag
     4321 cagcaatgta tagttgctct atggtcaata ccatccatcg accaaacatt aagctgatta
     4381 acagacacta tatgaggaag ttggctgagt tcatggtgca aagcgcaata gtctatcgaa
     4441 tcaggaacac catctaaaaa aatgttagcg gttgctacta actttggaag agctttagat
     4501 aatataaaag aagcaatggc aattgataat aaaggatcaa gaatgtacca aggtttccat
     4561 tttaagatca gtgacagtat gataatggct aaccatccaa ggatatcttc taaaaagtga
     4621 aggcttaata tttcttcatt ttttgtctgg ttagagtgaa tgatgaagct agcaaatcca
     4681 ttgattataa ttgcaaaaat agctaaaacg aacataccgt cataattaac aatagtagga
     4741 tgccataatt ttggtatcgt ttcaatcatt actaataatg acccgctaat aagtattaga
     4801 tttgtcgtta gcgctcctaa aaggctaaat cgcttatagc ctagtgaaaa atttggactc
     4861 tcttttttaa cagcctttct ttctaagata gctgagatac caatagcaat ggcatctcca
     4921 aaatcgtgga cagcatctgc taaaatagca cccgaaaaga ataatgttcc aaaaataaat
     4981 tcaatgaggg aaaaactaag atttaatata aaaataatgg tgactttttt acttgctggc
     5041 ataattttct ccttttgt
//
LOCUS       DATWEK010000067         5050 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.067, whole genome shotgun sequence.
ACCESSION   DATWEK010000067 DATWEK010000000
VERSION     DATWEK010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5050
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.067"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            36..254
                     /locus_tag="VCR92_001753"
     CDS             36..254
                     /locus_tag="VCR92_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin NrdH"
                     /protein_id="HEP4268795.1"
                     /translation="MITVYSKNNCMQCKMTKKFLEQHGANFQEINIDEHPEKVDYVKS
                     LGFTSAPVIEADNLVFSGFQPAKLKELI"
     gene            274..2433
                     /gene="nrdE"
                     /locus_tag="VCR92_001754"
     CDS             274..2433
                     /gene="nrdE"
                     /locus_tag="VCR92_001754"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEP4268796.1"
                     /translation="MSLKDIGDISYFRLNNEINRPVNGKIPLHKDKEALKAFFAENVL
                     PNTMSFTSITEKIEYLISNDYIESAFIQKYRPEFITELDSIIKSENFRFKSFMAAYKF
                     YQQYALKTNDGEYYLENLEDRVLFNALYFADGQEDLAKDLAVEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARKNEDMYLFSPYNVEKEYGIPFNYLDITNMYDELVANPKI
                     TKTKIKARDLETEISKLQQESGYPYIINIDTANKANPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVEMGTDISCNLGSTNILNMMTSPDFGRSIKTMTRALTFVTDSSSIEAVPT
                     IKHGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLLNYWTLVESNNIAR
                     ERQTTFVGFENSKYANGSYFDKYVTGHFVPKSDLVKSLFKDHFIPQASDWEALRDAVQ
                     KDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFLRSELPMELYEWKTQSKQTTRDLS
                     ILRNYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            2766..3725
                     /gene="nrdF"
                     /locus_tag="VCR92_001755"
     CDS             2766..3725
                     /gene="nrdF"
                     /locus_tag="VCR92_001755"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEP4268797.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSLQEKDLVGKVFGGLTLLDTMQSETGVEAIRADVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEEIFEWTNNNEFLQEKARIINNIYANGDALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFR
                     DWMYDLLYQLYENEEKYTKTLYDGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGSVEAMSDDDYNYGL"
     gene            3700..5013
                     /locus_tag="VCR92_001756"
     CDS             3700..5013
                     /locus_tag="VCR92_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEP4268798.1"
                     /translation="MTIIIMDSNSAHETDNLSVSFLNFCYNSLMKRHFLLLTFYLFLT
                     GLTAGLVAFILTKAIHLIQSLSFGFSQGSFSTMIASVPPQRRALSLLFAGLLAGLGWH
                     LLAKKGKDIQSIQQIIQDDISFSPWTQFWHGWLQLTTVSMGAPVGREGASREVAVTLT
                     SLWSQRCNLSKADQKLLLACASSAALGAVYNAPLATILFILEAILNRWSLKNIYAACL
                     TSYVAVETVALLQGRHEIQYLMPQQHWTLGTLIWSVLAGLILSLFAHAYKHLLEHLPK
                     ADAKSQWFIPKVLIAFSLIAGLSIFFPEILGNGKAGLLFFLHEEPHLSYISWLLVAKA
                     VAISLVFASGAKGGKIAPSMMLGGASGLLLAILSQYLIPLSLSNTLAIMVGATIFLGV
                     INKIPLAAPVFLVEITGQSLLMIIPLALANLIFYFSYQFYRFILK"
BASE COUNT         1496 a         1025 c          898 g         1631 t
ORIGIN      
        1 agatggaacc attactaatt ttagaaggac aagacatgat tacagtatat tccaaaaata
       61 attgcatgca gtgcaaaatg actaagaaat ttttagaaca acacggagcc aacttccagg
      121 aaattaatat cgatgaacat cctgaaaaag tggattatgt gaaaagtctt ggcttcacat
      181 ctgctcctgt tatcgaagca gataacctcg tattttctgg cttccaacct gcaaagttaa
      241 aagaattgat ttaataagac aaggaaaaat aatatgagtc tcaaagatat tggcgatatt
      301 tcatattttc gcctaaataa tgaaattaac cgtcctgtta atggtaaaat tccacttcat
      361 aaagacaaag aagctttaaa agcttttttc gctgaaaatg tgctgccaaa caccatgtct
      421 tttacttcca ttacggaaaa aattgagtat ttaatctcaa atgattacat tgaatcagct
      481 tttattcaga aataccgtcc tgaatttatt actgaattag atagcataat caaatcagaa
      541 aattttcgct ttaaatcatt tatggcagcc tacaagttct accagcaata cgccttaaaa
      601 acaaatgatg gagagtatta tttagaaaac cttgaagacc gtgtcttgtt taatgctttg
      661 tattttgcag atggtcaaga agacttagca aaagatttag ccgttgaaat gattaaccaa
      721 cgttaccaac cggctactcc ttccttttta aatgctggtc gaagccgtcg tggtgaattg
      781 gtctcttgtt tcttgattca agtaactgat gacatgaatt ctatcggacg ttccattaac
      841 tctgccttgc aattatcccg tattggtgga ggtgttggga ttaccttgtc taacctccgt
      901 gaagctggcg caccaatcaa aggctatgct ggtgcagcct caggagttgt tcctgttatg
      961 aaattatttg aagatagttt ttcttattca aatcaacttg ggcaacgtca aggagctggt
     1021 gttgtttacc taaatgtttt tcatcctgat atcattgctt tcttatctac taaaaaagaa
     1081 aatgccgatg aaaaggtgcg tgttaaaacc ttgtcactag ggattaccgt tcctgataaa
     1141 ttctacgaat tagctcgtaa aaacgaggac atgtatctct ttagtcctta caatgttgaa
     1201 aaagaatatg gcattccctt taactatctc gacattacca atatgtacga tgagttagtg
     1261 gcgaacccta aaattactaa gactaaaatt aaagctcgtg atcttgaaac agagatttca
     1321 aaattacaac aagaatctgg ttacccttat atcatcaata ttgatacagc taataaagct
     1381 aatcctatcg atggaaaaat catcatgagc aacttgtgtt ctgaaatttt acaagttcaa
     1441 acacctagcc ttatcaatga tgcgcaagag tttgtagaaa tgggaactga tatttcatgt
     1501 aacttaggtt ccactaatat cctgaacatg atgacctcac cagactttgg ccgttctatt
     1561 aagaccatga cacgtgccct aacttttgtt actgattcat caagcattga agctgttcca
     1621 accattaaac atggcaatag ccaagctcat acttttggcc ttggagctat gggactacat
     1681 tcttaccttg ctcaacatca tattgaatat ggcagtccag aatccatcga gtttactgat
     1741 atttacttta tgctcctgaa ttattggacc ttggtcgaat ccaataacat cgctcgtgag
     1801 cgccaaacta cctttgttgg ctttgagaac tctaagtacg ctaatggtag ttactttgat
     1861 aaatacgtta caggacactt tgttccaaaa tctgatttgg tcaaaagtct ctttaaagat
     1921 cactttattc cgcaagcttc agattgggag gctcttcgcg acgccgttca aaaagatggt
     1981 ctttatcatc aaaaccgtct agcagttgct ccaaatggct ctatttctta tatcaatgac
     2041 tgctctgctt ctattcaccc aatcacacaa agaattgaag aacgtcaaga aaagaaaatt
     2101 ggtaaaatct actatcctgc aaatggtttg tctacggata ccattcctta ctatacatct
     2161 gcttacgata tggacatgcg caaagttatt gatgtctatg ccgctgcgac cgaacatgtg
     2221 gaccaaggct tgtcattaac tctattcctt cgtagtgagt tgcctatgga gctttatgag
     2281 tggaaaacac aaagcaaaca aaccactcgt gatttatcca tcttacgaaa ctacgctttc
     2341 aataaaggca ttaaatctat ctactatatc cgtaccttta cggatgatgg ggaagaagtg
     2401 ggcgcaaacc aatgtgaatc ttgtgtcatt taattggtta agaagtaatg atgctaaagc
     2461 atctattact tctacggcag tcgctttagg cgatctgcct aaaccactca ctaactacgt
     2521 aaggaaagta ttatcgactt tccttactcc gtgtcgtaat tcctcgatat gccctaatga
     2581 tgctaaagca tctattactt cttggacaat cgctttaggc gttccgccta aaccactcac
     2641 tgactcattc gttacccttt tgaatctatt taaacttatt attaccggta gaactttggt
     2701 cggttctact ggtttatctc gatatcctta acgcacttta ctactcttta ggagatcatt
     2761 tttctatgac tacatattat gaagcaatta actggaatga aatcgaagac gtcattgaca
     2821 agtcaacttg ggaaaagttg accgaacaat tttggcttga tacccgtatc cctttatcaa
     2881 atgacttaga cgattggcgc aaactttctc ttcaagaaaa agatcttgtt ggcaaggttt
     2941 ttggaggatt aaccctactt gataccatgc aatcagaaac tggtgtcgaa gctattcgtg
     3001 ctgatgttcg cactcctcac gaagaagctg tcttaaacaa tattcaattt atggaatcag
     3061 ttcatgctaa atcatactcg tctatctttt caaccttaaa caccaaaaaa gaaattgaag
     3121 agatctttga gtggactaat aataatgagt tccttcaaga aaaagcacgt attatcaata
     3181 acatttacgc taatggagat gccttacaaa agaaagttgc ctcaacatat ctcgaaactt
     3241 tcctttttta ttctggcttt ttcacccctc tttactattt gggaaataat aagctagcaa
     3301 atgttgctga aatcattaaa ctaattattc gtgatgaatc tgtacatggt acttatatcg
     3361 gttacaaatt ccagcttggt tttaacgaac taccagaaga tgagcaagag aattttcgtg
     3421 attggatgta tgacctcctt tatcagctgt atgaaaatga agaaaaatac accaaaacgc
     3481 tttatgatgg cgtagggtgg actgaggaag ttatgacctt tttacgctac aatgctaaca
     3541 aagctcttat gaatttagga caagatcctt tattcccaga tactgcaaac gatgttaacc
     3601 caattgttat gaatggtatt tcaacaggaa catcaaacca tgactttttc tcacaggtag
     3661 ggaatggcta tcttcttggt tctgtagaag ctatgtctga tgacgattat aattatggac
     3721 tctaatagtg ctcacgagac tgataatcta tcagtctctt ttcttaactt ttgttataat
     3781 agtcttatga aacgacactt tttactcttg accttttacc tctttttaac aggtttaaca
     3841 gctggccttg ttgcttttat cttaacaaaa gccattcacc tgattcagtc cctcagtttt
     3901 ggattcagtc aaggttcttt tagcactatg attgctagcg ttccaccaca aagacgagct
     3961 ctttcacttc tctttgctgg acttcttgca ggtcttgggt ggcacctatt ggctaaaaaa
     4021 ggaaaggaca ttcaatctat tcagcaaatc attcaagatg acatctcatt tagtccctgg
     4081 acacagtttt ggcatggttg gctccaatta acgaccgtat ctatgggagc tcctgtcggc
     4141 cgagaaggag cttcacggga agtcgctgtt accttgacgt ctctttggag ccaaagatgc
     4201 aacttgtcaa aagccgatca aaaactttta ttagcttgcg cttctagcgc tgcccttggt
     4261 gctgtctaca atgctccctt agccactatt ttatttatct tggaagctat tcttaaccgt
     4321 tggtccctta aaaatatata cgctgcctgc ctaacgagct atgtggctgt ggaaacagtt
     4381 gctttattac aaggccgaca tgagattcaa tacctaatgc ctcagcaaca ttggacgcta
     4441 ggaaccctta tttggtccgt cctggctggt cttatccttt ccctctttgc tcacgcttac
     4501 aaacatcttt tggaacacct tcctaaggct gatgccaaaa gtcagtggtt tattccgaaa
     4561 gttctcatcg cttttagcct tatcgcagga ctcagcattt tcttcccaga gattttagga
     4621 aatggcaaag ctggattact cttttttctc catgaagaac cacatctgag ctatattagc
     4681 tggctacttg ttgccaaagc tgtcgctatc tctttagttt ttgcttctgg agcaaaaggg
     4741 ggtaaaattg ctccttctat gatgcttgga ggtgctagtg gcttactact agctatcctt
     4801 agtcagtacc ttattccctt gtctctatca aatacgttag ccattatggt tggtgcaaca
     4861 atctttttag gtgtgatcaa taagataccc ttggcggcac cagtttttct ggttgaaatt
     4921 acaggccaat cgttactaat gattatccct ttagcattag ctaacctcat tttttatttt
     4981 agctatcagt tttatcgttt catccttaaa tgattagtta attacttttt taataaaaag
     5041 cttcggatga
//
LOCUS       DATWEK010000068         4985 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.068, whole genome shotgun sequence.
ACCESSION   DATWEK010000068 DATWEK010000000
VERSION     DATWEK010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4985
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.068"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            8..877
                     /locus_tag="VCR92_001757"
     CDS             8..877
                     /locus_tag="VCR92_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEP4268799.1"
                     /translation="MYHTTALSFLKKGYQVIPLRKDTGTPMIKFKDIQITEEVIKNTN
                     WFNCDYALLMRGIWCIDIDTHDMDEKLAKELYIMIKKMGIDLLSVLSTDKYDNGLDGY
                     SSIIRHEYKNELISNFKNTFAELTASGGMHILFKKRDGINYTQKIGVMPGVDIKANDN
                     NFVKIFPSDGREVLQAVKTLPYYDGKFEEEAFKPKQEGITTYFGGSVTYTSNGSHEGR
                     EAYERVATGTSYNRNNDLFKGACWAFENGIDIDDLTSIIGTVKGRDVFTREEFELTIE
                     SAKRKVSYVTIRT"
     gene            831..1181
                     /locus_tag="VCR92_001758"
     CDS             831..1181
                     /locus_tag="VCR92_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEP4268800.1"
                     /translation="MNQRNEKSATSLSEHDIQNLIRMELSQAGHMVFRANVGKVKTAD
                     GRFFDTGLPKGFCDLFGFKPNGQIFFIEVKNETGRIRPEQKKFMEVMASRGALVGVAR
                     SVEDALNIVNDTSR"
     gene            1165..1521
                     /locus_tag="VCR92_001759"
     CDS             1165..1521
                     /locus_tag="VCR92_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268801.1"
                     /translation="MTLVDDFYKQMEPSIKAFLDDNITIADKEEADRVYRSVKYYKKL
                     NRLPPPDVLEWFQRIYTTKEMIMLIKQSYRLKQKKTDEDDKIYEKWMFKNYGDVKLVK
                     KIKRTDALERARRMGL"
     gene            1763..1999
                     /locus_tag="VCR92_001760"
     CDS             1763..1999
                     /locus_tag="VCR92_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HEP4268802.1"
                     /translation="MIEELVHKPKHYNHGEIDLIESWYKTYPWDQFVAIMESHIDKYI
                     KRHRYKGNATQDLEKALEYTKRLIEYWLIESVEE"
     gene            1996..2166
                     /locus_tag="VCR92_001761"
     CDS             1996..2166
                     /locus_tag="VCR92_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268803.1"
                     /translation="MKRYIEVKDEWKSATDHLNDFIDKNKYAKVTVVGYQVVQLSPYG
                     RDLTYILAEVEE"
     gene            2163..2447
                     /locus_tag="VCR92_001762"
     CDS             2163..2447
                     /locus_tag="VCR92_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268804.1"
                     /translation="MTIDEALQNLRDNFNKIMNVLKNDWKALLFLAIAIFGMMVTVSY
                     FSYRDARQYYESQITGLRTQLSRTQKQLKRASEDRARQTKRIAEFTHNGG"
     gene            2449..3081
                     /locus_tag="VCR92_001763"
     CDS             2449..3081
                     /locus_tag="VCR92_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEP4268805.1"
                     /translation="MIKIDEIHRILGIDEVYKAPKRLTDILFDKDSREDIFRQFLKYE
                     TDVSYDWFMQYFEEEQADRKNKKQDFTPKSVSTLLSKIISGNQYYEVAVGTGGILIQA
                     WQEQRLNDSPFTYRPSKYWYHVEELSDKAVPFLLFNMSIRGINGVVVHGDSLTRQVKN
                     IYFLQNTKDDMLSFSDINVMPRTQDIEQEFNVKEWIGDAIVHVESKLNAR"
     gene            3086..3565
                     /locus_tag="VCR92_001764"
     CDS             3086..3565
                     /locus_tag="VCR92_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEP4268806.1"
                     /translation="MNIEEAIKKIRELEAFNYFDFKGNLIRRIDVLGIIDQLKIIVQQ
                     CVADWYEKHKDNLEYDLYLYQMSIYDEKVEEDDFYYWMQKSKNPVRTLINMHQFGYEI
                     EQEQLYTVDLPNGQPLVRGKNTLYFSQNLTAENAKLTESEIRKDFEWAWQFAKEVTE"
     gene            3562..3732
                     /locus_tag="VCR92_001765"
     CDS             3562..3732
                     /locus_tag="VCR92_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268807.1"
                     /translation="MTEELGVLYSEKWHKYYLYKTCRYISYVDNPHQATKCTRKQAEQ
                     FPQFKWVSLTKL"
     gene            4014..4448
                     /locus_tag="VCR92_001766"
     CDS             4014..4448
                     /locus_tag="VCR92_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEP4268808.1"
                     /translation="MTFFPEINIQKTKSNAKRKLREYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVPSKPVERLALNRVSAEQELDAIEQAVSMILEPERRRILYDKYLAPYKKAD
                     KVIYTELCMSESFYYDTLDIALLAFAELYREGVLLVEQGVFS"
BASE COUNT         1781 a          788 c         1063 g         1353 t
ORIGIN      
        1 ttaccttatg taccacacaa cagcactttc attcttaaaa aaaggatatc aggttatacc
       61 gcttagaaaa gatactggaa cgccaatgat taagtttaaa gatatccaaa taacggaaga
      121 agtgatcaaa aatacaaact ggtttaattg tgattatgct ttattaatgc gtggcatttg
      181 gtgtattgat attgatactc atgacatgga cgagaagtta gctaaagagt tatacataat
      241 gataaaaaag atggggattg atttattatc tgtattatcg actgataagt atgacaatgg
      301 actagatggt tattcgtcaa ttattaggca tgagtataaa aacgaattaa tcagtaattt
      361 taaaaataca ttcgcagaat taactgcaag tggtggtatg cacatactct ttaaaaaacg
      421 cgatggtatt aattacacgc aaaaaatagg agtaatgcct ggtgttgaca taaaagcgaa
      481 tgataataat tttgtcaaaa tattcccatc tgacggacgt gaagttttac aagcagttaa
      541 aacattacct tattatgatg gaaaatttga agaggaagca tttaaaccaa aacaagaagg
      601 tataacaacc tattttggag gttctgtcac atatacatca aacggaagtc acgaaggccg
      661 agaggcttat gaacgtgtag caactggaac atcatataac aggaataatg atttgtttaa
      721 aggagcgtgt tgggcgtttg aaaatggtat cgatattgat gatttaacat caattattgg
      781 gacggttaaa ggcagagacg tatttacgag agaggagttt gaattaacga ttgaatcagc
      841 gaaacgaaaa gtcagctacg tcactatcag aacatgatat ccaaaacctt atccgaatgg
      901 aattatcaca agcggggcat atggtatttc gagcaaatgt cggaaaggtg aaaacagcag
      961 atggtagatt ttttgataca ggtttaccaa aaggtttttg tgatttgttt ggatttaaac
     1021 caaacggaca aatatttttt atcgaagtta aaaatgaaac aggtcggata agaccagaac
     1081 agaaaaaatt tatggaggtc atggcatcta gaggagcgct tgtaggagtg gctcggtcag
     1141 tggaagatgc cttaaacata gtcaatgaca ctagtagatg atttttacaa acaaatggag
     1201 ccgtcaatta aagcgttttt agacgataac attaccatcg cagacaaaga agaagctgac
     1261 agagtctata gatctgtcaa atactataaa aaactaaaca gattgccgcc acctgatgta
     1321 ttggagtggt tccaacgaat ttacacgaca aaggaaatga taatgttaat caagcagtct
     1381 taccgcctta aacaaaaaaa gacagatgag gatgacaaga tttacgaaaa gtggatgttt
     1441 aaaaactacg gtgacgttaa gctcgttaaa aaaatcaaac gcacggacgc actagaaaga
     1501 gctcggagaa tgggtctatg aaaagacaca gacagtggca taacgatatt aaatatacac
     1561 ctagatctta cgataatctg ttgccttacg atatatcaga gctgttaata gctcacagat
     1621 gcaaaataaa gatgtctgat gacgttttag cagataagat aggcatttat acttggcaat
     1681 taaaagcgct cttagaacgc agaatattgc caaatgagag cgagtgtaaa ttgattataa
     1741 attttttgag agaggtggag tgatgataga agaattagta cataaaccaa agcattataa
     1801 tcacggagaa attgatttga ttgagtcgtg gtataagacg tacccatggg accagtttgt
     1861 cgcaatcatg gaaagtcaca ttgataaata cattaaacga catagataca aaggcaatgc
     1921 gactcaggat ttagaaaaag cactcgaata tacaaagcgt ctcattgaat attggttaat
     1981 cgaaagcgtg gaagaatgaa gagatatatt gaagttaagg acgaatggaa aagtgcaaca
     2041 gaccacctga acgattttat cgacaaaaac aagtacgcaa aagtgacagt tgttggttat
     2101 caagtcgtac aactttctcc ttacggaaga gatttgactt atattttggc agaggtggaa
     2161 gaatgacaat agatgaagcg ttgcaaaatt tacgtgataa ctttaataaa ataatgaatg
     2221 tcctaaaaaa cgattggaaa gcactattgt ttcttgcaat cgcaatattt gggatgatgg
     2281 taaccgtgtc gtattttagc tatcgcgacg cacgacaata ttacgagtcg caaatcacag
     2341 gactacgtac acagctaagc aggacacaaa agcagcttaa acgtgctagc gaagatagag
     2401 ctagacagac aaagcgaatt gcggaattta cgcacaacgg agggtaacat gattaagatc
     2461 gatgagatac atcgcatact aggcatcgac gaagtttata aagcacccaa acgacttacg
     2521 gacatactct ttgataaaga tagtcgtgag gatatattta gacagttttt gaaatatgaa
     2581 acagatgtat cctacgactg gtttatgcaa tattttgagg aagaacaagc tgaccgcaaa
     2641 aataaaaagc aagactttac gcctaaatcg gttagtacac tattatctaa aataataagt
     2701 ggtaatcaat actacgaggt agcagtcggg acgggtggga tacttatcca agcatggcaa
     2761 gaacaacgat taaatgacag tccatttact tatcgtccga gtaaatactg gtatcacgta
     2821 gaagagttat cggacaaagc agtaccgttt ctactcttta atatgtctat aagagggata
     2881 aatggtgtgg tggtgcatgg tgactcttta acaagacaag ttaaaaacat ttattttttg
     2941 caaaatacaa aagacgacat gctgagtttt agtgatatta acgttatgcc aaggactcaa
     3001 gatattgagc aagaatttaa tgtcaaagag tggattggtg atgcgatagt gcatgtagag
     3061 agtaagttaa atgcgaggta acaaaatgaa cattgaagaa gctattaaaa agataagaga
     3121 actagaggcg tttaattatt tcgactttaa aggtaattta attagaagaa ttgatgtatt
     3181 aggtatcatc gaccaactaa aaattatagt acaacaatgt gttgcagatt ggtacgaaaa
     3241 gcataaagat aatttggaat atgatttata tttatatcaa atgtcaatct atgatgaaaa
     3301 agttgaagaa gatgattttt attattggat gcaaaaatca aagaatccag ttcgtactct
     3361 tattaatatg caccaatttg gctatgaaat cgagcaagag cagctgtata cagttgattt
     3421 gccaaacggt cagcctttag tacgcggtaa aaacactttg tattttagtc aaaatctaac
     3481 agccgaaaat gcaaaactca ctgaatcaga aatccgaaaa gacttcgagt gggcttggca
     3541 atttgcgaaa gaggtgactg aatgactgaa gagttaggag tgttatatag cgaaaaatgg
     3601 cataagtatt atttatataa aacttgcagg tatatatctt atgttgataa tccacatcag
     3661 gctactaaat gcacccgcaa acaagcagaa cagtttccac agtttaaatg ggtatcgctg
     3721 acaaaattat aaccccacgc aagcgctcaa gagcctgcga tggctctgtg ggggtggacc
     3781 gaaattaaaa aatagaaacg agaacctcct tacaccaaaa caaatctaaa gcgggttatc
     3841 ggtcatccgt gattatccaa ggcgtcgcta atgctttaac acgacatcgt gcgcctgtgt
     3901 caaaaaacaa aggaaagaga gggcttttct ccacaaaaca aaaagacgtc cacacggaac
     3961 gcccccttgg ttaaatttaa gcttaaataa attataccac atcgggggct ttcatgacgt
     4021 tttttccaga aattaatata caaaaaacta aatcaaacgc taagcgaaaa ctaagagagt
     4081 atccacgctg gcgaaggata gctaatgacg tagatactca aaaagttaca gctacttact
     4141 catttgagcc aaggcaaccg catggggtcc ctagtaaacc agttgagaga ctagcgctaa
     4201 accgtgtgtc agcagaacaa gagctggatg cgattgagca agccgtcagt atgatactag
     4261 agccagagag acgcaggatt ttgtatgaca aatatttagc gccttataaa aaggcagata
     4321 aggttattta tacagaattg tgtatgtcag agagctttta ctatgataca cttgacattg
     4381 ctttgttagc ttttgcagag ctgtacagag agggtgtgtt gcttgttgag caaggagttt
     4441 ttagctagtt tttatacagt aataagatag tttatacata tttttacatg ttattatagt
     4501 actatcaaaa taacaagaag agataacctt ttaatcactg actattttat ttagtcgcca
     4561 actttaacta cgatcaaact tgttatttta tggtatgtgg gacgtgcagg ttcgaatcct
     4621 gccgtctcta tcagcgtcag gggagacgcg accccacacc catttaaagg tagacacgat
     4681 ctgatgtgtg gggttttatg attaaccgca agtaaaacaa gggtcgcaac cttgcttgtg
     4741 gttagtaggc ttaatggtcg tttatgcacg ttcgattcgt gcaaagcctg ttaggaacat
     4801 gaaccgtgat tggaaaacgg tggaggtagc gccttgcttc gggacgttag ctaagtccga
     4861 aaactctttg cgaagagcca gaagaagatg tgtcggttcg attccgactg ttcctgttgc
     4921 atttaatgca aactccatat ttttattaaa aaagcctatt atacctattg tgtaagggct
     4981 ttttt
//
LOCUS       DATWEK010000069         4767 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.069, whole genome shotgun sequence.
ACCESSION   DATWEK010000069 DATWEK010000000
VERSION     DATWEK010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4767
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.069"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            56..1252
                     /locus_tag="VCR92_001767"
     CDS             56..1252
                     /locus_tag="VCR92_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEP4268809.1"
                     /translation="MKKRILSAVLVSGVTLGAAITVGAEDLSTKIAKQDSIISNLTTE
                     QKAAQNQVSALQAQVSSLQSEQDKLTARNTELEALSKRFEQEIKALTSQIVARNEKLK
                     NQARSAYKNNETSGYINALLNSKSISDVVNRLVAINRAVSANAKLLEQQKADKVSLEE
                     KQAANQTAINTIAANMAMAEENQNTLRTQQANLVAATANLALQLASATEDKANLVAQK
                     EAAEKAAAEALAQEQAAKVKAQEQAAQQAASVEAAKSAITPAPQATPAAQSSNAIEPA
                     ALTAPAAPSAGPQTSYDSSNTYPVGQCTWGAKSLAPWAGNNWGNGGQWAYSAQAAGYR
                     TGSTPMVGAIAVWNDGGYGHVAVVVEVQSASSIRVMESNYSGRQYIADHRGWFNPTGV
                     TFIYPH"
     gene            1505..2467
                     /locus_tag="VCR92_001768"
     CDS             1505..2467
                     /locus_tag="VCR92_001768"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEP4268810.1"
                     /translation="MSYSDLKLFALSSNKELAEKVASAMDLQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGEDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGNVSGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQRSAIEKLIVL
                     DTIYLPKERLIDKIEQISIADLVAEAIIRIHEKRPLSPLFEMGN"
     gene            2653..3408
                     /gene="recO"
                     /locus_tag="VCR92_001769"
     CDS             2653..3408
                     /gene="recO"
                     /locus_tag="VCR92_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEP4268811.1"
                     /translation="MQLTESLGIVLFNRNYREDDKLVKIFTEVAGKQMFFVKHISRSK
                     MSSIIQPLTIADFIFKLNDTGLSYVVDYSNVNTYRYINNDIFRLAYASYVLALADAAI
                     ADNESDSHLFTFLKKTLDLMEEGLDYEILTNIFEIQILDRFGISLNFHECAICHRTDL
                     PLDFSHRFSAVLCSEHYYKDNRRNHLDPNVIYLLSRFQKITFDDLRTISLNKDIKKKL
                     RQFIDELYHDYVGIKLKSKTFIDNLVKWGDIMK"
     gene            3511..4518
                     /gene="plsX"
                     /locus_tag="VCR92_001770"
     CDS             3511..4518
                     /gene="plsX"
                     /locus_tag="VCR92_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEP4268812.1"
                     /translation="MKRIAIDAMGGDNAPKAIVEGVNQAIEAFSDIEIQLYGDQTKIN
                     SYLIQSDRVAIIHTDEKIMSDDEPAKAVRRKKKASMVLAAKAVKEGKADAIISAGNTG
                     ALLAVGLFVVGRIKGVDRPGLLSTIPTVTGLGFDMLDLGANAENTAKHLHQYAILGSF
                     YAKNVRGIANPRVGLLNNGTEETKGDPLRKATYELLTADNTISFVGNVEARELMSGVA
                     DVIVSDGFTGNAVLKSIEGTAISIMGQLKQIINSGGIKTKIGASLLKSSLYEMRKTLD
                     YSSAGGAVLFGLKAPVVKSHGSSDVKAIFSTIKQVRTMLDTNVVGQLVEEFAKETQVN
                     D"
     gene            4511..4753
                     /locus_tag="VCR92_001771"
     CDS             4511..4753
                     /locus_tag="VCR92_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017228.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEP4268813.1"
                     /translation="MTRQEIFERLINLIQKQRSYLSVAITEQTHLKNDLAVDSIELVE
                     FIINVEDEFHLAIPDEDVEDMVFMGDVLDYLVQRLT"
BASE COUNT         1545 a          739 c          987 g         1496 t
ORIGIN      
        1 tttttttttt ggtaaaatat aagatgtctt atcgaaaagg agtagttttt ttattatgaa
       61 aaaaagaatt ttatcagcag ttcttgtaag tggtgttacc ctcggagcag ctataactgt
      121 aggagcggag gatttaagta ctaagattgc taagcaagat tctattatct caaatctgac
      181 tacagagcaa aaagctgcac agaatcaagt ttcagcgtta caggctcaag taagttcact
      241 acaatctgaa caagataaac tgaccgcaag aaatacagaa cttgaggcgc tttcaaagcg
      301 atttgagcaa gaaattaagg ctctaacaag tcaaattgtt gctcgtaatg aaaaattaaa
      361 aaatcaagct cgtagtgctt ataaaaacaa tgaaacttct ggttatatta atgcactttt
      421 gaattctaaa tcaatttctg atgttgtaaa ccgtttagta gcaattaata gagctgtctc
      481 tgctaacgct aaattgttag aacaacaaaa agctgataaa gtttcccttg aagaaaagca
      541 agctgctaac caaacagcta ttaataccat tgccgctaat atggcaatgg ctgaagaaaa
      601 ccaaaataca ttacgtactc aacaagctaa tttggtagct gcaactgcaa atttagctct
      661 ccaattagca tctgctactg aagataaagc taatttggta gctcaaaaag aagctgcaga
      721 aaaagctgct gctgaagcct tagcacaaga acaggctgct aaagttaagg cacaagaaca
      781 ggctgcacaa caagcagcat ctgttgaagc agcaaaatct gctattactc cagcaccaca
      841 agctactccg gcagcgcaaa gtagtaatgc tattgaacca gctgcactca cggctccggc
      901 agctccttct gcaggaccac aaacatcata tgattcttct aatacttatc cagttggaca
      961 atgcacatgg ggagctaaat ctttagctcc ttgggcagga aataattggg gaaatggtgg
     1021 tcaatgggct tatagtgctc aagcagctgg ttatcgtact ggttcaacgc cgatggtagg
     1081 tgcgattgcc gtttggaacg atggtggtta tggacatgtc gccgttgtag ttgaggttca
     1141 aagtgcctca agtattcgtg tgatggagtc taactacagt ggtagacagt acattgctga
     1201 ccaccgtggc tggtttaatc caacaggtgt tacatttatt tatccacact aacatattat
     1261 ttaggttaga acagttgttc taaccttttt gattactcct attgtggaat agttctgaga
     1321 gtattgacga tatagttaat ttataagaga gttgtttggc caatcgctta tgtataatat
     1381 aagagaagta tataaagtcg ataaaaggta tatttaatac attctttaac ggtttttcaa
     1441 tttcatttga taattcactt gaaaagcgtt aaaatggtat aggattaaaa ctttggagga
     1501 aaaaatgtct tattctgatt taaaattgtt tgctttatcg tcaaacaagg aattagcaga
     1561 aaaagttgcg tctgcaatgg atcttcaact tggaaagtct acggttcgcc agttttcaga
     1621 tggtgaaatc caagtaaata ttgaagaatc aattcgtggt catcatgtct ttattttgca
     1681 atcaactagc tcacctgtca atgacaattt aatggaaatt ttgattatgg tcgatgcttt
     1741 aaagcgtgct agtgctgaaa aaatttcagt tgtgatgcct tactacggct atgcacgcca
     1801 agaccgtaaa gcgcgttctc gtgaacctat tacttcgaaa ttagttgcta atatgttaga
     1861 agttgctggt gtagatcgct tattaacggt tgatttacat gctgctcaaa ttcaagggtt
     1921 ctttgatatt ccagttgatc acttgatggg tgcaccttta attgcagact attttgatcg
     1981 tcatggttta gtgggtgaag atgttgtcgt tgttagtcct gaccatggtg gtgtgactcg
     2041 tgcgcgtaaa ttagcacaat tcctccaaac accaattgca attatcgata agcgtcgtag
     2101 tgtggataag atgaacacca gtgaagtgat gaatattatc ggaaatgttt cgggcaagaa
     2161 atgtatcttg attgacgata tgattgatac cgcagggact atttgccatg cagcagatgc
     2221 gcttgctgaa gcgggggcaa cagctgtgta tgcgtcatgt acgcatcccg ttctttctgg
     2281 accagcactt gataatattc aacgttcggc tatcgaaaaa ctaattgttc ttgatactat
     2341 ttatctgcca aaagaacgcc ttattgataa aattgaacaa atttcaattg ctgatttggt
     2401 tgcagaagcg attattcgca ttcatgaaaa acgtccgttg tcacctttat ttgagatggg
     2461 caattaaact taacgaagcc tgagataata gatctcaggc tttttgactt gaataaaatg
     2521 taagggtaat gtggtattaa ttattgtggg atgaactatg caattctaaa ggattttggg
     2581 tataataaga aagataacaa cagtttattg taaactaaga taaaaggtaa gagaaaaata
     2641 cgacgaggta atatgcaact aacagaatca ctaggcatcg ttctttttaa taggaattat
     2701 cgagaagatg ataaattagt caaaatattt actgaagtag caggtaagca gatgtttttc
     2761 gtgaaacata ttagtcgttc caaaatgtcc tcaatcattc aaccactaac gattgctgat
     2821 tttattttca agttaaatga tacaggcttg tcttatgttg ttgactatag taacgttaac
     2881 acttatcggt atattaataa tgatattttt cgattagcct atgctagtta tgtcttagca
     2941 ttagctgatg ctgcgattgc agataatgaa tcagattcgc atttgtttac gtttttgaaa
     3001 aaaacacttg atttgatgga agagggccta gattatgaaa ttttgacaaa tatttttgaa
     3061 attcagatat tagatcgttt tggtattagt ctaaactttc atgagtgtgc catttgtcat
     3121 cgcactgatt taccgcttga tttttcccat cgtttttcag ctgtactttg ttctgaacat
     3181 tattacaaag acaaccgacg taatcattta gatccaaatg ttatctactt gttgagtcga
     3241 tttcaaaaaa tcacatttga tgatttgaga actatttcat tgaataaaga catcaaaaag
     3301 aagcttcgtc agttcattga tgagttgtat cacgactatg taggaatcaa attaaaaagt
     3361 aaaacattca ttgataattt agttaagtgg ggagatatta tgaaatgata gggcctcttt
     3421 cgtttatggg aattggtttc agaatatgct ataataaaaa tactattaat agattgtgta
     3481 agaacacaag atataattaa aggagtggaa atgaagagaa ttgcaataga tgctatgggt
     3541 ggagataacg ctcctaaagc tattgttgag ggtgttaatc aagcaataga agcattttca
     3601 gatatcgaaa ttcaacttta cggtgatcag acaaagatta actcctatct tattcaatca
     3661 gatcgtgttg ctattattca tacagatgaa aaaattatgt cagatgatga acctgcaaaa
     3721 gctgttcgcc gtaaaaagaa ggcttcaatg gttttagcag ctaaggcagt gaaagaagga
     3781 aaagcagatg ccattatttc agcaggtaat acaggtgctc ttttagctgt aggtttgttt
     3841 gttgtggggc gtatcaaggg agttgatcgt ccaggattat tatcaactat tcccacagta
     3901 accggattag gatttgatat gttggatctt ggagctaatg ctgaaaatac ggcaaaacat
     3961 ttacatcaat atgctatttt aggctctttc tatgctaaga atgtacgtgg gattgctaat
     4021 ccacgtgttg gtctattaaa caatggtaca gaagaaacaa aaggagatcc ccttcgtaag
     4081 gccacttatg aacttttaac agcagataat acaatatctt ttgttggtaa tgtcgaggcg
     4141 cgagaactta tgtcaggtgt tgcagatgtt attgtatcag atggtttcac gggaaacgca
     4201 gtgttgaaat caatagaagg aacagctatt agcattatgg ggcaactgaa acagataatt
     4261 aatagcggcg gtattaagac taaaattgga gctagtctac ttaaaagtag tctttacgag
     4321 atgaggaaga ctcttgacta ctctagtgct ggaggtgcag ttttatttgg tttaaaggca
     4381 cctgttgtaa agtctcatgg ttctagtgat gtaaaagcta ttttttcaac gataaaacaa
     4441 gtacgtacga tgctagacac taacgtggtc ggacaattag tagaagaatt tgctaaggag
     4501 actcaagtaa atgactagac aggagatttt tgaaagactg attaacttaa ttcagaagca
     4561 aagaagctat ttgagtgtag ctattacaga acaaacacat ttaaaaaatg atttagcggt
     4621 tgactctatt gaactagttg aatttattat taatgttgaa gatgaatttc atcttgctat
     4681 tcctgatgaa gatgttgagg atatggtatt tatgggagac gttttagatt atttagttca
     4741 gcgtttgact tagttagaat aataaaa
//
LOCUS       DATWEK010000070         4465 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.070, whole genome shotgun sequence.
ACCESSION   DATWEK010000070 DATWEK010000000
VERSION     DATWEK010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4465
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.070"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            26..871
                     /locus_tag="VCR92_001772"
     CDS             26..871
                     /locus_tag="VCR92_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEP4268814.1"
                     /translation="MTFILHYLEQSHIENIGLTIFKKLVSLIILLLFFAILKRVTNYL
                     FEKTINKSFAYSRQSEARKKTLSKLTHNILNYLLYFLLIYWILSLFGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDNVTISDIEGSVFGVGIRTTQIRGFD
                     GTLHFIPNRSITVVSNKSRGNMRALIEIPLYSTVNLSQVTRIIDEVNQKELPNHPQIV
                     GKPNILGPQNNSNGQFTFRIAIFTENGEQFKIYHTFYRLYQEALLKEGIQLPTAISYS
                     ITSKS"
     gene            complement(936..1496)
                     /locus_tag="VCR92_001773"
     CDS             complement(936..1496)
                     /locus_tag="VCR92_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEP4268815.1"
                     /translation="MLNNLEKQTREIVIDVVERSAIQPGNLFVLGLSSSEILGSRIGK
                     QSSLEVGQIVVEVVLDELNKRGVHLAVQGCEHVNRALVVERHVAESKQLEIVNVVPNL
                     HAGGSAQMAAFQFMSDPVEVEEVIAHAGLDIGDTAIGMHIKRVQIPLIPCQRELGGAH
                     VTALASRPKLIGGARADYNMDIIRKS"
     gene            complement(1510..1980)
                     /locus_tag="VCR92_001774"
     CDS             complement(1510..1980)
                     /locus_tag="VCR92_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEP4268816.1"
                     /translation="MQNSKIRQMSLTGILTALVVVLGRFVMLPTPTGFLTLLDAGIYA
                     VSFSFGSAQGAIVGGLSGFLIDLVAGYPQWMFHSLIAHSVQGYFAGWRGRKRWLGVVI
                     GSFIMIFWYFLGSLMLGYGLSGSLAGIWGNVMQNTLGLFVGFIIFKAILRQKKR"
     gene            complement(1970..2734)
                     /locus_tag="VCR92_001775"
     CDS             complement(1970..2734)
                     /locus_tag="VCR92_001775"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEP4268817.1"
                     /translation="MKTDYIVTISGNDILSGGGLYADLATYIRYDLQAFVAVTCLTTR
                     SEEGFSLFPVAKEIFRDQLNSFTNAPISAIKIGLLPNAEMCEIVLDFIKGHLGIPVVL
                     DPVLACKEIDDVKIVPLRQEILQLLPYVTVVTPNLVEAQLLSQKEIVSLKDMQEAAKY
                     FYQLGAKQVVIKGGNRFSQKKAIDLFYDGKEIVTLECPVLEKNNIGAGCTFASSIASQ
                     LVKKKTPLEAVKNSKELVYQAILQSDRYGVKQSYAK"
     gene            complement(2724..3473)
                     /gene="truA"
                     /locus_tag="VCR92_001776"
     CDS             complement(2724..3473)
                     /gene="truA"
                     /locus_tag="VCR92_001776"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEP4268818.1"
                     /translation="MVRYKATISYDGTLFSGFQRQRHLRTVQEEIEKTLYKLNNGTKI
                     IIHGAGRTDAGVHAYGQVIHFDLPQEQEVEKLRFALDTQTPEDIDVVNIEKVADDFHC
                     RYQKHLKTYEFLVDNGRPKNPMMRHYTTHYPYTLNIKLMQEAINGLVGTHDFTGFTAA
                     GTSVQNKVRTITKATVSRDEKTDFLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQ
                     VKVILSSKNRQLAGPTISGNGLYLKEICYEN"
     gene            complement(3658..4239)
                     /locus_tag="VCR92_001777"
     CDS             complement(3658..4239)
                     /locus_tag="VCR92_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEP4268819.1"
                     /translation="MHNEKSNRTLVSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKV
                     KPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERLYRYFKTKFSSYL
                     KDLLCRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQER
                     MQFQALIRGERFKGRRALLRKISPYFKEFAQQL"
     gene            complement(4235..4308)
                     /locus_tag="VCR92_001778"
     tRNA            complement(4235..4308)
                     /locus_tag="VCR92_001778"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4272..4274),aa:Arg,seq:acg)
     gene            complement(4388..4461)
                     /locus_tag="VCR92_001779"
     tRNA            complement(4388..4461)
                     /locus_tag="VCR92_001779"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4425..4427),aa:Asn,seq:gtt)
BASE COUNT         1415 a          989 c          658 g         1403 t
ORIGIN      
        1 taaactatca aagaaaggat ttctcatgac atttatatta cattacctag agcagtctca
       61 tatcgaaaat attggcttaa cgatttttaa aaagctagtg tctctcatta ttctattact
      121 cttttttgct attttaaaac gtgttactaa ctatcttttt gaaaaaacca ttaacaaatc
      181 gtttgcttat tcaagacaaa gtgaagctcg caaaaaaaca ctctctaagc tcactcacaa
      241 tattttaaat tacttattgt attttcttct catttattgg atacttagct tatttggcat
      301 acctgtctct agtcttctag caggagctgg aattgctgga gtagcaatcg ggttaggtgc
      361 acagggattt ttatctgacg ttgtcaatgg cttttttatc ttatttgaga atcaatttga
      421 agtaggagat aacgttacta tctctgacat agaaggcagt gtctttggtg ttggaattag
      481 aactactcaa attcgtggat tcgatggaac actacatttc atcccaaacc gtagcatcac
      541 cgttgtcagc aacaaatctc gtggtaatat gcgtgcctta attgaaattc ctctttattc
      601 cactgttaat ttgagccaag tcactcgaat cattgatgaa gtgaatcaaa aggaattgcc
      661 aaaccatcct caaatcgttg gcaaaccaaa tattttaggg cctcaaaata actctaatgg
      721 acagttcact tttagaattg ctattttcac agaaaatgga gaacaattta agatttacca
      781 tactttttat agactttatc aagaagcttt actcaaagaa ggcattcaat taccgactgc
      841 aatcagctat tctatcacct caaaatctta atataatctt aaaaaatcct tttttctaga
      901 aaaaacacca attgttttat tccagaaaaa agggtttagg atttacggat aatatccata
      961 ttgtaatcag ccctagctcc accaattaat tttggtcgac tagccaaagc tgtcacatga
     1021 gcacctccta gctctcgttg acaaggaatc agagggatct gaacacgctt aatatgcatt
     1081 cctatagcag tatcacctat atcaagtcca gcgtgtgcaa taacttcttc tacttcgaca
     1141 gggtctgaca taaattgaaa agcagccatc tgagcactgc caccagcatg aagattcgga
     1201 accacattga caatctctaa ctgcttagat tctgccacat gcctctctac taccaaggca
     1261 cgattgacgt gttcacaacc ttgtacagcc aaatgaacac cacgcttatt taattcatct
     1321 aacacaactt caacaactat ttgacctact tctagactag attgttttcc aattctacta
     1381 cccaaaattt cgctagatga aagacctaga acaaaaagat tacctggttg aatagcagag
     1441 cgttctacaa catcaatgac gatttccctt gtttgtttct ctaaattatt caacaacttc
     1501 tcactctcct tatctctttt tttgccttaa tatggcctta aagataataa aaccaacaaa
     1561 aagccctaat gtattttgca tgacgtttcc ccaaataccg gctaaagatc ccgaaaggcc
     1621 ataaccaagc ataagagagc ctaaaaagta ccaaaaaatc atgataaaag aacctatcac
     1681 aacaccaagc caacgcttgc gccctctcca tcccgcaaaa tacccttgga cactgtgagc
     1741 aatcaaacta tgaaacatcc actgagggta tcctgccact aaatcgatta aaaaacctga
     1801 taaccctccc acaatagctc cttgagctga tccaaaggaa aagctgacag cataaattcc
     1861 tgcatccaac agcgttaaaa aacctgttgg agtaggtagc atgacaaatc ttcctaaaac
     1921 aacaaccaat gctgtcaata tccctgttaa actcatttgt cgtatcttac tattttgcat
     1981 aactttgttt tactccgtat ctatcagatt gtaaaatagc ttggtagact aactcttttg
     2041 agtttttcac agcttctagt ggcgtttttt tctttactaa ctgactagcg atactagatg
     2101 caaaagtaca gcctgcgcca atattatttt tctcaagtac aggacattcc aaggtaacaa
     2161 tctctttacc gtcataaaaa agatcaatag cctttttctg actaaatcga ttaccaccct
     2221 tgataaccac ctgttttgcc ccaagttgat aaaaatattt agcagcttct tgcatatctt
     2281 ttaaagaaac aatctctttt tgagataata gctgagcctc taccaaattt ggagtaacaa
     2341 cagttacata aggcaataat tgtaaaatct cctgtcttag aggaactatt ttaacatcat
     2401 ctatttcttt acatgctaga acaggatcta aaaccactgg gattcccaga tgccccttta
     2461 taaaatccaa aactatttca cacatttccg cattaggtaa caaaccaatt ttaatagcag
     2521 aaattggagc gttcgtaaag ctattcaact gatcacggaa aatttcttta gctaccggaa
     2581 atagactaaa gccctcttca gatctagtag ttaaacaagt taccgctaca aaggcctgta
     2641 ggtcatacct tatgtaagtc gctaaatcag catagagacc acctccactt aaaatatcgt
     2701 tcccagatat agtcacgata taatcagttt tcataacaaa tctccttcaa gtaaagccca
     2761 tttccagata tcgttggtcc agctagctga cgatttttgg agctcaaaat cactttaact
     2821 tgttcaactg gcatttgacc attaccaatt ttcagcaaag ttcccaccat attcctcacc
     2881 tgcttataga gaaaaccatt tcctgaaaaa gtaaacacca aaaaatcagt tttttcatcc
     2941 cgagataccg ttgctttggt aatcgttcgc accttatttt gtaccgaagt tcctgctgct
     3001 gtaaaaccag taaaatcgtg tgtacctacc agaccgttaa tagcttcttg cataagttta
     3061 atattaagag tataagggta atgagtggta tagtgtcgca tcatcggatt tttaggtcga
     3121 ccattatcaa ctaaaaattc ataagttttt aaatgcttct gataacgaca atgaaaatca
     3181 tcagccactt tttctatatt aacaacatca atatcttcag gagtctgtgt atcaagagca
     3241 aatcgtaatt tttcaacttc ttgttcttga ggcaaatcaa aatggatcac ctgtccataa
     3301 gcatgtactc ctgcatccgt acgtcctgca ccatgaatta taatttttgt accgttattt
     3361 aatttataga gtgttttttc aatctcttct tgaaccgtac gtaaatgtct ttgtctttga
     3421 aaacccgaaa aaagagtccc atcataggaa atcgttgctt tgtatcttac catgttacta
     3481 ttttaacatt tcttaaacgt aagagaaact atttttaatc aaactgtacc caaacaaatg
     3541 aaagacgtat tgaagcttac tctaagccac tagcgattta aaagctataa gaaagctatt
     3601 tcctccaaac tctctccttt tttcgtagat ttacccctaa ttccttatag gtcttgctta
     3661 caactgctgt gcaaattcct taaaataggg actgatcttc ctaagtagag cacgtcttcc
     3721 cttgaaacgt tcgcccctga taagtgcttg aaactgcata cgctcttgcg aatttaattg
     3781 gttctctaag ctagctatta cctcttgata agccacatag tcgtctagcc ataaccctct
     3841 cgatggaatg gcatgtgcaa cctcccctat ctcttcatat gctaacttat ggaactgacg
     3901 cttttgactt tcttgacggc ataataaatc tttcaaataa gatgaaaatt ttgttttaaa
     3961 atagcgatat aaacgctctt cttcctcaat taactctggg tacctttcta gtaactgtaa
     4021 taagataata tgtccttctt gtaaccagtc atctctatcc cacaattgaa tataatagtg
     4081 tcgctttaat ttcaaaataa tgggcttaac tttttcaaac gctgctcttg tctctatcga
     4141 cattttgagt ctccttttct ttttaactat ccctagtata aagagaacca caaaaaaaca
     4201 acaggacact aatgtcctgt tgcttttttc attatgcacc ctagaggagt cgaacctcta
     4261 accgcctgat tcgtagtcag gtactctatc cagttgagct aagggtgcca acgcatatct
     4321 tgcctctatc ttaccacact cttctctaaa atgcaaaaaa agataggacg cttcctacct
     4381 ctctctactc cgccagtagg actcgaacct acgacatcat gattaacagt catgcgctac
     4441 taccaactga gctatggcgg ataaa
//
LOCUS       DATWEK010000071         4446 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.071, whole genome shotgun sequence.
ACCESSION   DATWEK010000071 DATWEK010000000
VERSION     DATWEK010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4446
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.071"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..103)
                     /locus_tag="VCR92_001780"
     CDS             complement(<1..103)
                     /locus_tag="VCR92_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HEP4268820.1"
                     /translation="MDEFKGIKVEFIQLSNKNIFDVLEKDLSKKLRFE"
     gene            complement(89..214)
                     /locus_tag="VCR92_001781"
                     /pseudo
     CDS             complement(89..214)
                     /locus_tag="VCR92_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769756.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
     gene            complement(319..591)
                     /locus_tag="VCR92_001782"
                     /pseudo
     CDS             complement(319..591)
                     /locus_tag="VCR92_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424370.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(610..915)
                     /locus_tag="VCR92_001783"
     CDS             complement(610..915)
                     /locus_tag="VCR92_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEP4268821.1"
                     /translation="MKEYQVTMSDDAKADLLSIYHYVRDELCAPQAADNLLERLSQEM
                     LSLSIFPERCAIIEDLIGKGYTFRQLIVKKYRIVYHVLEDEVIIVAVVYGSRHMNNW"
     gene            complement(915..1217)
                     /locus_tag="VCR92_001784"
     CDS             complement(915..1217)
                     /locus_tag="VCR92_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEP4268822.1"
                     /translation="MAKTGTLNLRVDDSVKSAADDILKRLGIPMSTAIDMFLNQIILT
                     GGIPFDVSLPEAPQRVNVDYMSQEKFYDKLIFSFEDAKTGNRKDVREFLSQLKENA"
     gene            complement(1272..1448)
                     /locus_tag="VCR92_001785"
     CDS             complement(1272..1448)
                     /locus_tag="VCR92_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HEP4268823.1"
                     /translation="MGQNVVMRQAPGGNIKPDKEKSVEKIDGIVGLILGLDRCIRRQG
                     DEASVYDERGILSF"
     gene            1464..2357
                     /locus_tag="VCR92_001786"
     CDS             1464..2357
                     /locus_tag="VCR92_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268824.1"
                     /translation="MTTMLDFPFHHEFIEFLGRWTHILITLLKRHHGQADTAIPRYLL
                     VTIREKTGIVKSTTVQNTAFTTQSNQLKKQYGQFLLTESNNCCACPGCDRPLILTSGN
                     LAAENYEVSAIEKDKDAEPLNLIALCPDCFLTYQADSRKKIVTALKNVKKILVSAHNS
                     QQAISDMKLDSGIVSVLTSLNKLKCDEYDISYDSKQLTDKISPENNRTLYQLVKNPVI
                     DNYLTIQKIIVNLDKQGKIDYEEIQYQTRSMYKKLKAAKHNNLAIFNTISEKLHKATL
                     QDIYFCQTIVSYFIQKCEVLE"
     gene            2357..2581
                     /locus_tag="VCR92_001787"
     CDS             2357..2581
                     /locus_tag="VCR92_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268825.1"
                     /translation="MQLPNKLYSYQKSTLAYLPRVLNEIKSGNSNVKDIFHAISEELD
                     DPTDFLSIMDCLYALNAIEMSNEGEVKLCL"
     gene            2572..4230
                     /locus_tag="VCR92_001788"
     CDS             2572..4230
                     /locus_tag="VCR92_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2326 domain-containing protein"
                     /protein_id="HEP4268826.1"
                     /translation="MLIEMWSPVFKNHGEIRESICFHYGLNVIMGMDLADNSIGKSSS
                     LLAIDFIFGGNSYLKSIAVKKLGDHPIYFCFQFEKKFYFSRDTANPDIILVCDKSYSP
                     TGETMDLGIFLNKLKKRYHLDSPELSFRLAMSGFFRIAGKSNQNTDFPLQVYSSQKSS
                     ESITTLIQLFNLYDNIARYKERLKDKSDQLTTFRNARKYTFISNLVGGKKQFEANVSE
                     IKRLEYDLAHLQDTHQDKIDSDDIEKNQQKLQLRNTKLELESSLRDKQRRLKLLDISI
                     EFGLYPTESDLTELQQYFPDTNLKKLYEVEAYHKKLETILDSEFSTERESLIAEIDEL
                     ESQLTTLNQELQELGNIPNLSSEYLESYSKLTATINALKEQNEAYLKESGLSKEKSEA
                     DADLKRSTEDILLDLEVKINSKMREFNNILYPDIRKAPQINLNAHNSYSFYTPDDDGT
                     GTKFKGMIVFDLVMLYLTNLPALTHDSLLLSNVSYQATEALLKLYDQSRSLNKQVFLA
                     FDKASSYSPDANQLLSENTVLRLSSNGNELYGISWNKGENSDEI"
     gene            4220..4429
                     /locus_tag="VCR92_001789"
     CDS             4220..4429
                     /locus_tag="VCR92_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP4268827.1"
                     /translation="MRFSYNKLWKLLIDKGWTKTKLRQEAGISSSTIAKLGKGENITT
                     DILLEICIALDCKIEDIVEIVDNNI"
BASE COUNT         1500 a          905 c          735 g         1306 t
ORIGIN      
        1 cttcaaatct taacttttta gataaatctt tctccaaaac atcaaatata tttttgttag
       61 acagttgaat aaattctact ttaattcctt taaactcatc cacattctcg ccactagtcg
      121 tgcgaccaaa gaggtagaaa aagtcctgac cttcataact gttttgaggc ttatctctag
      181 ccctttttct tccaattaaa tcaagtagtc ccataagccc tccttatttt ggggtacaaa
      241 aaaagcacct cctttgaagt gctttcggta tatttctttc aaagtaatca acagtctttc
      301 ttacaaaacc tagtattctc attctgtcaa ttccttaaat gcgtcaagat gtcgtgataa
      361 tactgaagtc gcaatctcat ctaaccttgc ttgttcaaca actgttgtca tctgctcatc
      421 actgcttaaa ctttggtgat ccgctgatag tttgctatca gatggactta ataccaaagt
      481 tccatcagtt gatttataaa ggttaaactc ctaattctct tgaatgccaa atgggtcagg
      541 tatcggaaga tagatgtcat caccaatttg tatcgtcttt acgagttcca tacatcactc
      601 tcccttactt taccaattat tcatatgacg tgatccatag acgaccgcaa caattataac
      661 ttcatcttcc agaacatggt atacaatgcg atattttttg acaatcagtt gtctgaaggt
      721 atagcctttt ccaatcagat cctcaatgat ggcacaacgt tcaggaaaaa tggatagtga
      781 taacatttct tgggataacc tctcaagaag attatccgct gcctgtggtg cacagagttc
      841 atcacgaaca tagtgataga tgctcagcaa atctgcttta gcatcatccg acatggtgac
      901 ctgatattct ttcattaagc attttccttc aattgagata gaaattctct gacatccttg
      961 cggttgccag ttttcgcatc ttcaaagctg aagataagct tatcataaaa cttctcctga
     1021 ctcatgtaat caacattaac tcgttgaggc gcttcaggta gagaaacatc aaatgggata
     1081 cccccagtca aaataatctg attcaaaaac atatcaatcg cagttgacat aggaatacct
     1141 aagcgtttca aaatatcatc tgccgcactt tttactgaat catcaactcg taaattcaaa
     1201 gttcccgttt tagccatggt tatcctcctt ttttgtaacg acattgtatc acgtttttag
     1261 agttgactca actaaaaact caatatccct cgctcatcat agacgctagc ttcatcacct
     1321 tggcggcgaa tgcaacggtc aagccccagg ataagaccta caataccgtc aatcttctca
     1381 acagattttt ccttatctgg cttgatgttg cctccagggg cttgtcgcat caccacgttt
     1441 tgtcccatcc atttaaggac tggatgacca ccatgttaga ttttcccttc catcatgagt
     1501 ttatagagtt ccttggacgg tggactcata tccttataac tctgctcaaa aggcaccatg
     1561 gtcaagccga caccgcaatt ccaaggtatc ttctagtaac cataagagag aagacaggga
     1621 ttgtaaaatc aaccactgtg caaaatactg cgttcactac ccagtcgaat cagctcaaaa
     1681 aacaatacgg gcagttcttg ttaacagaat ctaataactg ttgtgcatgc ccaggctgtg
     1741 atagaccact cattctaacc agtggcaact tagcagcaga aaattacgag gtttcagcca
     1801 ttgaaaaaga taaggacgct gaaccactga atctgatagc cctctgccca gattgttttt
     1861 taacctatca agcagatagt cgcaaaaaaa ttgtaacagc tctaaaaaat gttaaaaaga
     1921 ttctagtctc tgcacataac agccaacaag cgatttctga tatgaagtta gacagtggaa
     1981 ttgtttcagt tttgactagt ctcaataaac taaaatgtga tgaatatgat atctcctatg
     2041 actcgaagca attgactgat aagatatcac ctgagaacaa tcgtacgctt tatcaattgg
     2101 ttaaaaaccc agttattgat aactacttaa ccattcaaaa aatcatcgta aatttggaca
     2161 aacaaggaaa aattgattac gaggaaatcc aatatcaaac gcgatcgatg tataaaaagt
     2221 taaaagcagc caagcataat aatctggcta ttttcaatac tatttcggaa aaactccata
     2281 aagctacact acaggacatc tacttctgtc agacgattgt ctcttacttt atccaaaaat
     2341 gcgaggtact tgaataatgc aattaccaaa taaactttac tcctatcaaa aaagcaccct
     2401 tgcttatttg cctagagtgc taaatgaaat caaaagtgga aactcaaacg tcaaagatat
     2461 ctttcacgct atctcagaag agttggatga tcctacagat ttcttatcta taatggattg
     2521 cttgtatgca ttgaacgcta ttgaaatgtc taatgaagga gaagtaaaat tatgcttata
     2581 gaaatgtggt ctccagtatt taagaatcac ggagaaattc gggaatcaat ctgcttccac
     2641 tatgggttaa acgtgattat ggggatggat ttagctgata actctatcgg caaatcctcc
     2701 tcactattag ccattgattt catctttgga ggtaatagct atctaaaatc aattgcggtt
     2761 aaaaaattag gtgatcatcc tatctatttc tgctttcaat ttgagaaaaa gttttatttt
     2821 tcaagagata cggccaaccc agatatcatt ctagtgtgtg acaagagcta ctctccaacc
     2881 ggtgaaacaa tggacctagg aatttttctt aacaaactta agaaacgata tcatttagat
     2941 tctccagagc tatcattccg attagctatg agtggcttct ttaggattgc aggaaaaagt
     3001 aatcaaaata ccgatttccc tttacaagtt tattcgagcc aaaaatcttc tgaatctatt
     3061 actactctca tccaactgtt taatttgtat gataacattg cacgatacaa agaacgtctg
     3121 aaagataaga gcgaccagtt aacaactttt cgtaatgctc gaaagtatac cttcatctcc
     3181 aacctggttg gcggtaaaaa gcaatttgaa gcaaatgtct cagaaataaa aagattggaa
     3241 tatgatttag cacatctcca agacactcat caagataaaa ttgactctga tgatattgag
     3301 aaaaatcaac aaaaactcca gcttagaaat actaagctgg agttagaaag cagtcttcgg
     3361 gacaagcaaa gacgtcttaa gctattggac atcagtatcg aatttggctt atatcctact
     3421 gaatctgact taacagagct tcaacaatac ttcccagata ctaatctcaa aaaattatat
     3481 gaagttgaag cttaccacaa aaaattggaa actattttag attccgaatt ctcaactgaa
     3541 cgtgaatccc taatagctga gatcgacgaa ttagagagtc aattaacaac tctaaaccaa
     3601 gaacttcaag aactaggaaa catcccaaat ctttcaagtg agtacttaga aagctactct
     3661 aaactaacag ctacaatcaa tgcactaaaa gaacaaaacg aggcctactt aaaggagtct
     3721 ggtctatcca aagaaaaatc agaagcggac gctgacttga aacgcagtac agaagatatc
     3781 cttctagatc tagaagtaaa aatcaacagt aagatgcgtg aattcaataa cattctatat
     3841 ccagatattc gcaaagctcc tcaaattaac ctcaatgctc acaatagcta ctccttctat
     3901 acaccagatg atgatggtac aggaactaag tttaaaggga tgattgtatt cgacttagta
     3961 atgctctacc ttactaatct gccagcactc acacacgatt cattactctt gagtaatgtt
     4021 agctaccaag cgactgaagc acttttgaag ctgtatgacc agtcaaggtc attgaacaaa
     4081 caagtctttt tagccttcga taaagccagc tcttattctc cagatgctaa tcaactcttg
     4141 tcagaaaata cggtattgag actctctagt aacggaaatg aactctacgg tatttcatgg
     4201 aacaaaggag aaaactcaga tgagatttag ttacaataaa ttatggaaac ttcttattga
     4261 taaaggttgg accaaaacaa agctcaggca agaagctggg attagttctt ccacgatcgc
     4321 aaaattggga aaaggggaaa atatcactac tgatatttta ttggaaattt gtattgcact
     4381 tgattgtaag attgaagata tagtagaaat tgtagataat aatatctaga aataaaaaaa
     4441 gcacta
//
LOCUS       DATWEK010000072         4329 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.072, whole genome shotgun sequence.
ACCESSION   DATWEK010000072 DATWEK010000000
VERSION     DATWEK010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4329
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.072"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(108..887)
                     /gene="spek"
                     /locus_tag="VCR92_001790"
     CDS             complement(108..887)
                     /gene="spek"
                     /locus_tag="VCR92_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeK"
                     /protein_id="HEP4268828.1"
                     /translation="MKKNTLTLLFLVCVSLALYTTESVFSDTYNTNDVRNPRNIYAPR
                     YDKDEILDNRRLKEIYNKEIIEKNNISINAKQGTQLIFNTDENTTVWNDNTFKKVISS
                     NLSPSQERMFNVGDHVNIFAIVKSYHVVCKEQFNYSDGGIIKTSDVKPEEKAIYINIF
                     GEKELRTLTAKDKITFKNNIVTLQEIDVRLRKSLMGDSKIKLYEYDSLYKKGFWDIHY
                     KDGGIRHTNLFTYPDYTDNETIDMSKVSHFDVHLNEDFSKD"
     gene            complement(1191..2057)
                     /locus_tag="VCR92_001791"
     CDS             complement(1191..2057)
                     /locus_tag="VCR92_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HEP4268829.1"
                     /translation="MGTIAPAFMELLLDANFCKAPVNNQDTLLKVYHREMAKDNVTIP
                     YEIIAEYVYSHEDSVEENEKLNSNIDFIISEFSGTDTQKDILIKNLDKIKSNYSLAQT
                     QKKFILKNSQEAKDVLEKIIPELNTLAKETSNLAATNDELKKQSAETDGVLQKVKQGV
                     DDVRNTKSSIYTDFIAILGVFSAFVFVMFGGIDVARAIFDIGNDLQTLDLSRMITVSS
                     LMLIGVLTLMYSLLLWVARITGKNFGNCYSSKCDNGCRHKWRHFLMRHSFYFSLMFLL
                     VLTTVVSHCLLK"
     gene            complement(2045..2569)
                     /locus_tag="VCR92_001792"
     CDS             complement(2045..2569)
                     /locus_tag="VCR92_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEP4268830.1"
                     /translation="MHALFVANYIIEYSNKKGYKINNLKLQKLLYFVNVRNILENGAP
                     LFEESMEKWKYGPVVPDVYHEYKRFGAFSISTDEMIMEYVEFSVSPFGELSDLEITEY
                     DSQKVENTQLIENTVDALHGFGPFELVDITHDHTPWKKYEDRIMDGVQGIKYTIEEIK
                     DFFGHNPGAKIWVQ"
     gene            complement(2709..3911)
                     /locus_tag="VCR92_001793"
     CDS             complement(2709..3911)
                     /locus_tag="VCR92_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEP4268831.1"
                     /translation="MTFLDDIKQGCLDGWTKYKILPSLTAAQAILESGWGKHAPHNAL
                     FGIKADASWTGKSFDTKTQEEYQPGIVTDIVDRFRAYDSWTDSIIDHGKFLNDNPRYK
                     AVIGETDYKKACYAIKAAGYATASSYVELLIQLIEENDLQSWDREALKNNKEETMTTA
                     NEIVQYCVNLANSGMGVDKDGAHGTQCCDLPCFVAKNWFGVDLWGNAIDLLDSASAQG
                     WEVHRMPTEANPKAGATFVQSVPYHQFGHTGIVIEDSDGYTMRTVEQNIDGNADALYV
                     GAPARFNTRDFTGVVGWFYPPYQGDTVTQPVSTEPQTSDTIVETAKTGTFTLDVAEIN
                     IRRWPSLASEVVGIYKQGDTVSFDSEGYANGYYWISYVGGLGMRDYLAIGQTDKDGNR
                     ISIWGKLN"
     gene            complement(4022..4207)
                     /locus_tag="VCR92_001794"
     CDS             complement(4022..4207)
                     /locus_tag="VCR92_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268832.1"
                     /translation="MNKWFKKVAIKTIKTMAQTAVGLIGSSMLITDINWPTMLSAVLL
                     SGLTCVLMNVSQIKEEE"
BASE COUNT         1322 a          887 c          651 g         1469 t
ORIGIN      
        1 tattcctcgg ttgaccgata gtgatgccta gaagtctact aaaaccgtct aattcatcaa
       61 aatctattta aatagactaa aaattaaatt aaaatagcat tcaaccacta atctttagaa
      121 aaatcttcgt ttaagtgaac atcaaagtga ctaactttac tcatatcaat cgtttcatta
      181 tctgtatagt cggggtaagt aaataaattg gtgtgtctaa tgccaccgtc tttataatga
      241 atatcccaaa accctttttt atacaaagaa tcgtactcat acaattttat tttgctgtcc
      301 cccatcaaac ttttcctaag tctaacatca atctcctgaa gagttacaat attattttta
      361 aaggtaatct tatctttagc tgttaatgtt cgtaattctt tttcaccaaa aatattaata
      421 taaattgctt tttcttctgg ttttacatca cttgttttta ttattccccc atcactataa
      481 ttgaattgtt ccttgcatac aacatgatat gactttacta tagcaaaaat attcacatga
      541 tcaccaacat taaacattct ttcctgtgaa ggagaaagat tactagatat gactttctta
      601 aaagtgttat cattccaaac tgtagtattt tcatccgtat taaaaatcaa ttgcgttcct
      661 tgtttggcat ttatcgatat attatttttt tcaataattt ctttattata tatttctttt
      721 aatcttctat tatccaaaat ttcgtcttta tcatatctag gagcatatat gttccttgga
      781 tttctaacat catttgtatt gtacgtatct gaaaagacac tctcagtagt gtatagagca
      841 agcgatacac acacaaggaa taacaaagtc aaggtatttt ttttcatttt ttctcctaac
      901 attttttaag tttaatcaat ttgtttagca agtatactat atttaaataa taattcaact
      961 ataattttaa aaaaacacaa aaaaaacatt atacagctat aaagcttaat ataataggat
     1021 tttatgtata caattattta acagcatcta ttcaagatag cctacttcat caggttggta
     1081 tgactaagtt tttaacttat cttcccccct ttttttgttt tagaagataa aagaattttc
     1141 ttgattttgc acacaaaaaa ccgccctcaa tcaagagagc ggttggtttt ttatttaagg
     1201 agacagtgac taactacagt tgttaaaaca agtaagaaca ttaaagaaaa ataaaatgaa
     1261 tgtctcatga gaaaatgacg ccatttatgc cgacacccat tatcacattt tgacgaatag
     1321 cagttaccga aatttttacc tgtaattcta gctacccaca gcaacaaaga atacatcaat
     1381 gtcaatacac cgattagcat tagacttgag acagtaatca tccttgataa atcaagagtc
     1441 tgaagatcat taccaatgtc aaatatcgcc cttgctacat ctataccacc aaacataaca
     1501 aaaacaaaag ctgaaaacac tcctaagata gcaataaagt ctgtgtagat tgaagatttt
     1561 gtattccgaa catcatccac tccttgctta actttttgca aaacaccgtc agtctctgcg
     1621 gattgttttt ttaattcgtc atttgtagct gcaaggttag aagtttcttt tgctaatgtg
     1681 tttagctcag ggataatctt ctccagaaca tctttagctt cttgagagtt tttaagtata
     1741 aattttttct gagtttgagc taatgaataa ttgcttttta ttttatcgag gttttttatc
     1801 aaaatatctt tttgtgtatc agtccctgaa aattccgaaa taataaagtc gatatttgag
     1861 tttaatttct cattttcttc aacgctatct tcgtgactat acacatattc agcaattatt
     1921 tcataaggaa ttgtgacatt atctttagcc atttccctat gataaacctt taataaagtg
     1981 tcttgattat ttactggtgc tttgcaaaaa ttagcatcta gtaataattc cataaacgct
     2041 ggagctattg tacccatatt ttagcccctg gattatgtcc aaaaaagtct tttatttctt
     2101 cgattgtata tttaattcct tggacaccgt ccattattct atcctcatac tttttccaag
     2161 gtgtatggtc gtgagtaata tcaacaagtt cgaacggacc gaacccatgc agagcatcaa
     2221 ctgtattctc aatcaattga gtattctcta ctttttgtga gtcatattca gttatctcta
     2281 agtcagataa ctccccgaat gggctgacgc tgaattcaac atattccata atcatctcgt
     2341 ctgtagaaat ggaaaaagct ccaaaacgtt tatattcatg atagacatca ggaacaaccg
     2401 gtccatactt ccacttttcc atactctctt caaaaagcgg agctccattt tcaagaatgt
     2461 ttcttacatt aacgaagtat aataattttt gcaatttaag gttattaatt ttgtagcctt
     2521 ttttatttga atactcaatt atataatttg caacaaataa cgcatgcatc tcaattacac
     2581 ctcctttttc ttaattataa catatttgtc aagtactata tcttgttagc taaaaagtta
     2641 gctaacacta catcttgatt aggataccaa aaaacagccc ccgcaaaaag cgagggcatt
     2701 tgtcttatct aatttaattt accccaaata ctgatgcggt tcccgtcttt atcagtctgt
     2761 ccaatagcta ggtagtcacg catacctaag cctccaacat agctaatcca ataatagcca
     2821 ttagcgtagc cctcgctatc aaagctgaca gtatcacctt gcttgtagat acctacaacc
     2881 tcgctggcta gacttggcca gcgtctgata ttgatctctg caacatcaag ggtaaaggtg
     2941 cctgtttttg ctgtctctac gatagtgtca gaagtttgcg gctcggtgct gactggttgc
     3001 gtgactgtat ccccttgata tggtgggtaa aaccatccaa caacgccagt aaagtcacga
     3061 gtattaaaac gagctggtgc gccgacatat aaggcgtctg cattgccatc aatgttttgt
     3121 tcaacagtcc gcatagtgta gccgtcgcta tcctcaatga caattcccgt atgtccaaat
     3181 tgatgatacg gcactgattg gacaaatgta gcgcctgctt ttgggtttgc ctctgttggc
     3241 atacgatgga cttcccagcc ttgcgcactt gcgctgtcta ataaatcaat cgcattgccc
     3301 caaagatcaa caccaaacca atttttagcg acaaaacaag gcaagtcaca gcattgcgtc
     3361 ccgtgagcac cgtctttgtc aacacccatg cctgaattag caaggttaac acagtattgt
     3421 acaatttcgt ttgcggttgt catcgtttcc tccttattat ttttaagagc ttctctatcc
     3481 caactttgta agtcgttttc ctcaatcagt tggattaaaa gttcgacata gctacttgcc
     3541 gtagcgtatc cagctgcttt aatagcgtaa caagcttttt tatagtcagt ctcaccgata
     3601 actgctttgt agcgtggatt atcgtttaaa aatttgccat gatcaataat actgtcagtc
     3661 caactatcat aggccctaaa tcggtccaca atatccgtga cgataccagg ctggtactcc
     3721 tcctgagttt tagtgtcaaa agacttacct gtccagctcg catcagcctt aataccaaat
     3781 aaagcgttat gtggtgcatg tttgccccaa ccgctctcta aaatagcctg agcagctgtc
     3841 aaggatggca agattttata cttagtccag ccatctaaac agccctgctt aatatcatct
     3901 aaaaaggtca tctgtcctcc ttatctaaaa acggataaaa gataagagca atcacagaca
     3961 gcggaacata cagtattgcg attgctataa ctaatgctaa tcgtgtgact gctcgcatgg
     4021 cttattcctc ttccttgatt tgtgacacat tcatgaggac acaagtaagt cctgacaaca
     4081 acactgctga tagcatagta ggccagttaa tatccgtaat caacatgctt gacccgataa
     4141 gaccaaccgc agtttgtgcc attgtcttaa ttgttttgat tgctactttt ttaaaccatt
     4201 tgttcatttt tcttctcctt ttttaaacag cgtgacaata cgctccttat taataatgac
     4261 ttcatcttcg acacgaccta aacgctcttc gtggcggtcg ataatttttt tggtaatctc
     4321 acggtcacg
//
LOCUS       DATWEK010000073         3988 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.073, whole genome shotgun sequence.
ACCESSION   DATWEK010000073 DATWEK010000000
VERSION     DATWEK010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3988
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.073"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            327..590
                     /locus_tag="VCR92_001795"
     CDS             327..590
                     /locus_tag="VCR92_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEP4268833.1"
                     /translation="MASKDFHIVAETGIHARPATLLVQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTISAEGADAEDAIAAIEETMTKEGLA"
     gene            595..2328
                     /gene="ptsP"
                     /locus_tag="VCR92_001796"
     CDS             595..2328
                     /gene="ptsP"
                     /locus_tag="VCR92_001796"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEP4268834.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETVTVADTNAEEARL
                     DVALQAAQDELSVIRENAVESLGEEAAAVFDAHLMVLADPEMISQVKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATINEESIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     VIAVNGITGEVIIDPSEDQVLAFKEAGAAYAKQKAEWSLLKDAHTETADGKHFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGDAMFRTQMRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMEEYANRALTECSTAEEV
                     LELSKEYVSED"
     gene            2513..3940
                     /locus_tag="VCR92_001797"
     CDS             2513..3940
                     /locus_tag="VCR92_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEP4268835.1"
                     /translation="MAKQYKNLVNGEWKLSENEITIYAPATGEELGSVPAMTQAEVDA
                     VYASAKKALSDWRALSYVERAAYLHKAADILVRDAEKIGAILSKEVAKGHKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPVNLA
                     GSKIAPALISGNVVALKPPTQGSISGLLLAEAFAEAGIPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGEGIGKLAGMRPIMLELGGKDSAIVLEDADLVLAAKNIVAGA
                     FGYSGQRCTAVKRVLVMDKVADQLAAEIKTLVEKLSVGMPEDDADITPLIDTSAADFV
                     EGLIKDATDKGATALTAFNREGNLISPVLFDHVTTDMRLAWEEPFGPVLPIIRVTTVE
                     EAIKISNESEYGLQASIFTTNFPKAFGIAEQLEVGTVHLNNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTTVKSVVFDIQ"
BASE COUNT         1251 a          729 c          870 g         1138 t
ORIGIN      
        1 ataaagctaa aaagcaagct ataaacttat ctaaaacaca acatattgtg ttgaaataaa
       61 aaacagaaac ctaaatattg tgtcaatctg gattcttatg gttagagctc tagcgttttg
      121 gtgatagaag ctaagcagtt ttaataaagc attaaagtct gaaaaataaa ttgtgaaaaa
      181 cgtgaaaata aaagaaaata atttcacatt ttttgtcgtt taaatattta atcttgaaaa
      241 taaaaaagca ttgtgctata atcggttgtt gtaagggtta tcatgtgatg gctcaaaaat
      301 acacaactta aaaggagaac catactatgg cttcaaaaga ctttcacatt gttgcagaaa
      361 caggtattca tgcgcgtcca gcgactttgc ttgttcaaac agctagcaaa tttgcttcag
      421 acatcactct tgactacaaa ggtaaagcag taaatctaaa atcaatcatg ggtgttatga
      481 gtcttggtgt tggtcaaggt gcagatgtta ctatctcagc tgaaggtgca gatgctgaag
      541 atgccattgc agcaattgaa gaaacaatga ctaaagaggg attggcataa gactatgaca
      601 gaaatgctta aaggaattgc agcctcagac ggcgttgctg ttgctaaagc atatctacta
      661 gttcagccgg atttgtcatt tgagactgtt acagtcgcag atacaaatgc agaagaagct
      721 cgccttgatg ttgcactcca agctgcacaa gacgagcttt ctgttatccg tgaaaatgca
      781 gtagaaagct taggtgaaga agcagcagcc gtttttgatg cccatttgat ggttcttgct
      841 gatccagaaa tgatcagcca ggttaaagaa acgattcgcg caaaacaaac gaatgcagaa
      901 acaggtctta aagaagtgac tgacatgttc atcaccatct ttgaaggcat ggaagataac
      961 ccatacatgc aagaacgtgc agcggacatc cgcgacgttg caaaacgtgt gttggctcac
     1021 cttttaggtg taaaacttcc aaatccagct acaatcaatg aagaatcaat cgttatcgca
     1081 cacgatttga caccttcaga tactgctcaa cttaacaaac aatttgtaaa agcatttgtt
     1141 acaaatatcg gtggtcgtac aagtcactca gctatcatgg cacgtacact tgagatcgct
     1201 gcggtacttg gaacaaatga tattacaaaa cgtgttaaag atggtgatgt gattgccgtt
     1261 aatggtatca ctggtgaagt gattatcgat ccaagcgaag atcaagtact tgcttttaaa
     1321 gaagctggtg cggcttatgc caaacaaaaa gcagagtggt ctctccttaa agatgcgcac
     1381 actgaaacag ctgatggcaa acactttgaa ttggctgcta atatcggtac gcctaaagac
     1441 gttgaaggtg ttaatgacaa tggcgctgaa gctgttggcc tttaccgtac tgagttcttg
     1501 tacatggatt ctcaagactt cccaactgaa gacgaacaat acgaagctta caaagcagtg
     1561 cttgaaggca tgaatggcaa acctgttgtg gttcgtacaa tggatattgg tggagataag
     1621 gaacttcctt actttgacct tccaaaagaa atgaacccat tcctcggttt ccgtgctctt
     1681 cgtatctcca tctctgaaac tggggatgcc atgttccgca cacaaatgcg tgcgcttctt
     1741 cgcgcctctg ttcacggaca acttcgtatc atgttcccaa tggtagcact tcttaaagaa
     1801 ttccgtgctg caaaagcagt ctttgacgaa gaaaaagcaa acttgcttgc agaaggcgtt
     1861 gcggttgctg atgacatcca agttggtatc atgattgaga ttcctgcagc tgctatgctt
     1921 gcagaccaat ttgctaagga agttgatttc ttctcaattg gaacaaacga ccttatccaa
     1981 tacactatgg cagcagaccg tatgaacgaa caagtatcat acctttacca accatacaac
     2041 ccatcaatat tacgtttgat caacaatgtg atcaaagcag cgcacgctga aggtaaatgg
     2101 gcaggtatgt gtggtgagat ggcaggtgac caacaagctg ttccacttct tgttggaatg
     2161 ggcttggatg agttttctat gtcagcaact tcagtacttc gtacgcgtag tttaatgaag
     2221 aaacttgact ctgctaagat ggaagaatat gcaaatcgtg cgcttacaga atgttcaaca
     2281 gcagaagaag ttcttgaact ttctaaagaa tacgtttctg aagattaacg ggttaaagag
     2341 ttggtttaaa ccagctcttt tttgctagct aaaaatacaa ttactttttg gtgtgaaatc
     2401 atttgagtta tcaaataatt atcagaattt tcagatattt agtgtagcca aatcttgaat
     2461 tatatcagaa aagtgataga ataagattac tatcataaaa ggagataaaa cgttggcaaa
     2521 acaatataaa aatttagtga acggtgaatg gaaactatca gaaaacgaga ttaccattta
     2581 cgcaccagca acaggtgaag agttaggatc agttccagcg atgacgcagg cagaggtaga
     2641 tgctgtttac gcttcagcta aaaaggctct atcagattgg cgcgccttgt cttatgtgga
     2701 acgtgcagct taccttcata aagcggctga tattttagta cgtgatgctg aaaagatcgg
     2761 cgcgattctt tcaaaagaag tagccaaagg tcacaaggca gctgtcagtg aagttattcg
     2821 taccgctgaa atcattaatt atgcagcaga agaagggctt cgtatggaag gtgaagttct
     2881 tgaaggtggt agcttcgaag ccgcaagtaa gaagaagatt gctattgttc gtcgtgaacc
     2941 agttggttta gttcttgcca tctcaccttt taattatccc gttaacttgg caggttctaa
     3001 aattgctcca gcccttattt caggaaatgt tgttgctctt aaaccaccaa cacaaggctc
     3061 tatttctggt ttgttactag cagaagcttt tgcagaagct ggtattccag caggtgtctt
     3121 taataccatt acagggcgag gttctgttat tggggattac atcgttgagc acgaagcggt
     3181 taactttatc aactttacag gttctactcc aattggggaa ggaatcggta aattagcggg
     3241 tatgcgacca attatgcttg agcttggcgg taaggattct gctatcgttt tggaagatgc
     3301 agatcttgtt ttagcagcga aaaatattgt agccggtgct tttggttact caggacaacg
     3361 ttgtacagcg gttaaacgcg ttcttgtgat ggacaaggtg gcggatcaat tggcggctga
     3421 gattaaaaca cttgttgaaa aactaagtgt cggaatgcct gaagacgatg ctgatattac
     3481 accattaatt gatacatcag ctgctgattt tgttgaaggg ttgattaaag atgcaactga
     3541 taagggagct actgctttga cagcctttaa tcgtgaaggc aatcttattt cacccgttct
     3601 ctttgatcat gtgacaactg acatgcgttt ggcatgggaa gagccgttcg gcccagtatt
     3661 accaattatt cgtgtaacca ctgtagaaga agccatcaag atttctaatg agtctgaata
     3721 tggtttgcaa gcttctattt ttacaactaa tttcccaaaa gcttttggca ttgctgagca
     3781 attagaagtt ggaactgttc accttaacaa taaaacacaa cgtggaacag ataatttccc
     3841 attcttaggc gctaaaaaat caggtgcagg ggtacaagga gttaaatatt ctatcgaagc
     3901 tatgacaact gttaaatctg ttgtatttga tatccagtaa taaaaaaaat aaacaaaaag
     3961 ttaggttaac ttaacttttt gtttattt
//
LOCUS       DATWEK010000074         3637 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.074, whole genome shotgun sequence.
ACCESSION   DATWEK010000074 DATWEK010000000
VERSION     DATWEK010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3637
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.074"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            19..372
                     /locus_tag="VCR92_001798"
     CDS             19..372
                     /locus_tag="VCR92_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268836.1"
                     /translation="MSRKGVQEYDVTNVSERSIKIIKKAMYDEGTGFKPIHFYGIAIC
                     EGTREFYRPTYPFVRSEEDLDNLKDFINLYETDLLTFYTHGHNYDFGCFIYGIGNDGK
                     DKFRDRWFKEGVIFY"
     gene            465..2705
                     /locus_tag="VCR92_001799"
     CDS             465..2705
                     /locus_tag="VCR92_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HEP4268837.1"
                     /translation="MKQTKVLTGIAVAALSTGTGLVQADDLSNTRPAKAAEVVTHMEV
                     TENQVADAKTKADEATKAVKDQEATVKAIEAEKSQAQQSLVEATTAVNDTEKLASEAT
                     PDGLTKAQEETEASQSAVTDAQAQLEAAQEAESKAQTAVDHQKETVAKASQAVNQAKA
                     ALTTSNQAADVSAAEEKVLEAQEAVTKAETQVSQAQEADAKHESDVRHAKEELDLKSQ
                     KLTEKQTTLEQVMAAIEAERLTKPVENGTYFNQRDNEWQKAYGGKTFAATGCVPSALA
                     MVFSELAKREVTPTEIADYLWHNTDEFNKHYGGTSGKGLVAATNHYGFASTHLDSQST
                     IIAALQAGHHVLAAVQNNKFSPWGSQYSHEIVLRGYSNGNTYVYDPYNRANIGWYPIA
                     NLWNEQSRDAIDTAEVGVPFFKITTQKMAQLEMAKAVANEGLDEAKQAVKQAEANVTA
                     LEQVISQTSQAKEQLAAAKANLVTAKDMLDKAKQTAKLTEQDLETKTANLKQAQEHLT
                     LKQDDLAKAQTELAAQEKSLEQLTQVLSLAQENLGRATKAVEQTKADLTQKQAYVTNL
                     KQVTKLRQESQAKVNQAKAVLSEASARLEQELETLKTLQAKEANLTAQYQAIFKAYQA
                     VLAVKHHSQLAESKAKLEAKGEEAVPVVNEVGHVTDYVSGPTQLADAVAVRTEETSSK
                     TKNTSPVSVKLMAKQGHQKALETIVTSQSSLPQTGEQVVSILSLVGLNFLGLSSFLGL
                     RKQEEK"
     gene            2875..>3637
                     /locus_tag="VCR92_001800"
     CDS             2875..>3637
                     /locus_tag="VCR92_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEP4268838.1"
                     /translation="MKQMETKGYGYFRKTKAYGLVCGITLAGALTLGTTSVSADDVTT
                     LNPATNLTTLQTPPTADQTQLAHQAGQQSGELVSEVSNTEWDNAVTTAQKAGVTVKQS
                     EKVTHDSLSSAQADLEKQTQAVTEATTKQEANTTAINQAVSENKAIDQANRDEKARVD
                     ALNTKGEADTKAKNETGQAQVDAQNKQAQAAADAMNAKLKADYEAKLTEIKQIESENE
                     AIRQRNQQASQATHQANQAAQAAYQEKLAEIERIKA"
BASE COUNT         1342 a          646 c          789 g          860 t
ORIGIN      
        1 gaaaagaaag gtattatgat gtctaggaaa ggagtacaag aatacgatgt aacaaatgta
       61 tctgaaagaa gtataaagat aattaagaaa gctatgtatg atgaaggaac aggttttaag
      121 ccaattcatt tttatggaat agctatctgc gaagggacta gagaatttta tagacctact
      181 tatccatttg ttagaagtga agaagattta gataacttaa aagattttat taacttatat
      241 gagacagatt tgttaacttt ttatacacat ggtcataatt atgactttgg ctgttttatt
      301 tatggtatag gaaatgacgg aaaagataag ttccgtgata gatggtttaa agaaggagtc
      361 attttctatt gaattttaaa ataattaaaa aaaagatgac ccaaggtaac attaaagtag
      421 tataataatc ttaataaagg aagttatagg aagggcaact acttatgaaa caaacaaaag
      481 tattaacagg aatcgcagtc gcagctttat ctacaggtac aggtcttgtg caggcagatg
      541 atttatcaaa cacaagacca gctaaagcag ctgaagttgt gacacatatg gaagtgacag
      601 aaaatcaagt ggcggacgct aaaacaaaag ctgatgaggc aacgaaagcc gttaaggatc
      661 aggaagctac ggttaaggct attgaggcag aaaaatctca agcacaacaa tctttagttg
      721 aggcgacaac agcagttaat gataccgaaa agttagctag tgaagcgaca ccagatggtc
      781 taacaaaagc ccaagaagag actgaggcta gtcaaagcgc tgttactgat gcacaagcac
      841 aacttgaagc agctcaagag gctgaatcaa aagcccaaac agcagttgac catcagaaag
      901 aaacagtcgc caaagcgtct caagctgtta atcaagccaa agcagctctc acgacaagta
      961 atcaagccgc tgatgttagt gcagcagaag aaaaagtgtt agaggctcaa gaagcggtta
     1021 cgaaagcaga aacacaagtt agtcaggctc aagaagcaga tgctaaacat gagtctgatg
     1081 tgagacatgc caaagaagag cttgacctta agtctcaaaa attaacagaa aaacaaacaa
     1141 ctctagaaca agtcatggct gcgattgaag cagagcgtct gactaagcca gttgaaaatg
     1201 gcacttactt taaccaaaga gataacgagt ggcaaaaagc ctatggtggg aagacctttg
     1261 cggcgacagg atgtgtgcct agtgctttgg ctatggtttt ttcagagctg gctaaaagag
     1321 aggtgacacc gactgagatt gctgattact tatggcataa cacagatgag tttaataaac
     1381 attatggtgg tacaagtggt aaaggacttg tagctgctac taatcattat ggctttgctt
     1441 caacacattt agatagtcaa tcaactatta ttgcagcttt acaagcaggt catcatgttt
     1501 tggctgcagt acagaataat aaatttagtc cttggggatc acaatatagt catgaaattg
     1561 tcttgcgtgg ttactcaaat ggcaatactt atgtttacga tccttataat cgagctaaca
     1621 ttggttggta ccctattgct aatttatgga atgaacaaag tcgtgatgct attgatacag
     1681 cagaggttgg agtacctttc tttaaaataa caactcaaaa aatggcacaa ctcgaaatgg
     1741 caaaagcagt agctaatgaa ggcttagatg aagctaagca agctgttaaa caagcggaag
     1801 caaatgtgac agccttagaa caagttattt ctcaaacctc acaagccaaa gaacaattag
     1861 ctgcagctaa ggctaactta gtcacagcca aagatatgct ggataaggct aaacaaacgg
     1921 ctaaattaac agaacaagac ttagaaacga aaacagctaa tcttaagcaa gctcaagaac
     1981 atctaaccct taaacaagat gacctagcta aagctcaaac ggagctagca gctcaagaga
     2041 aaagcttgga acagttaact caagtgcttt cattagctca agaaaatctt ggccgtgcta
     2101 caaaagcagt tgaacagact aaggctgatc ttacccaaaa acaggcttat gtgacgaatc
     2161 ttaagcaagt gacaaaactg agacaagaaa gtcaagccaa agtaaaccaa gctaaggcgg
     2221 ttctcagtga agcaagtgct cgtttagaac aagaacttga gaccttaaaa accttacaag
     2281 ccaaagaggc taacctaaca gcacagtatc aagctatctt taaagcctat caagctgttt
     2341 tagctgtgaa acaccactca caattggctg aaagcaaagc taagcttgaa gctaagggag
     2401 aagaagctgt tcctgtggtg aatgaagtgg gacacgtaac ggattatgtg tctgggccaa
     2461 cacagttggc tgatgctgta gcagtgagaa cagaagaaac atcatcaaaa acaaagaaca
     2521 cttctcctgt tagtgtgaaa ttgatggcca agcaaggtca tcaaaaggct cttgaaacta
     2581 tcgttacttc acaaagtagc cttcctcaga caggtgagca agttgtctct attttgagct
     2641 tagtaggttt gaatttttta ggcttaagta gttttttggg gcttaggaag caagaggaaa
     2701 agtaataaaa tatagaacaa gaggtcattc tttagagaat ggctttttga ttggagttat
     2761 gatgaaaata gtttttaatt ggaaggcaag attaccttcc ttttcttttt agtaaaacat
     2821 ataagacctg ggatcgtcac aaaaagcaac ctagaagaga gatgagaaaa taacatgaaa
     2881 caaatggaaa ctaagggtta tggttatttt agaaaaacaa aggcctatgg tcttgtttgt
     2941 ggtattactt tagcgggagc gttgacgttg ggtacaacaa gtgtttctgc ggatgacgta
     3001 actactttaa acccagcgac taacttaaca acgctacaaa cacctccaac agctgatcaa
     3061 acacagctag ctcatcaagc tggccagcag tcaggggagt tggtatcaga ggtgagcaat
     3121 accgaatggg ataatgctgt cacaacagct caaaaagcag gtgttactgt caaacagtct
     3181 gagaaggtca cacatgatag cttatcatct gcgcaagccg atttagagaa acaaactcaa
     3241 gctgtcacag aagcgacaac taaacaagaa gccaacacaa cagctattaa tcaagcagtt
     3301 tcggaaaata aagcgattga tcaagctaat cgtgatgaaa aagctagagt tgacgctctt
     3361 aatactaaag gggaagctga taccaaagct aaaaatgaaa ctggtcaagc ccaagtagat
     3421 gcacaaaata aacaagccca agcagcagct gatgccatga atgccaaatt aaaggcagac
     3481 tatgaggcca agttaacaga aatcaagcag attgaatcag aaaatgaagc tatccgtcag
     3541 cgcaaccaac aagctagtca agcgactcat caagccaatc aagcagccca agctgcctat
     3601 caagaaaagc tagcagagat tgagcgcatc aaagccg
//
LOCUS       DATWEK010000075         3328 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.075, whole genome shotgun sequence.
ACCESSION   DATWEK010000075 DATWEK010000000
VERSION     DATWEK010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3328
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.075"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            67..249
                     /locus_tag="VCR92_001801"
     CDS             67..249
                     /locus_tag="VCR92_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEP4268839.1"
                     /translation="MDNFLELQFEELVNISGGKGNIGSAIGGCLGGMLIAAAGGPITG
                     GAAAFVCVASGIAAYQ"
     gene            complement(440..1125)
                     /locus_tag="VCR92_001802"
                     /pseudo
     CDS             complement(440..1125)
                     /locus_tag="VCR92_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191693.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1444..1671
                     /locus_tag="VCR92_001803"
     CDS             1444..1671
                     /locus_tag="VCR92_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEP4268840.1"
                     /translation="MEIKKLETFHQMTIEKLAKVEGGKNNWQANVSGVIAAGSAGAAI
                     GFPVCGVACGYIGAKTAITLWAGVTGATGGF"
     gene            1684..1884
                     /locus_tag="VCR92_001804"
     CDS             1684..1884
                     /locus_tag="VCR92_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEP4268841.1"
                     /translation="MTTMKELTINDMASISGGNAPGDAVIGGLGGLASGLKFCKLPHP
                     VLAGGCVVGFTVGGAYLGYTAN"
     gene            2898..3299
                     /locus_tag="VCR92_001805"
     CDS             2898..3299
                     /locus_tag="VCR92_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268842.1"
                     /translation="MRNILRFLGIVIISAVILFSIGSFYDLPLMKNIQLICWSFILDL
                     FVFVYKQRQTTEVLTWYQVVKQFWLFIKCTILIPTLIAFIIIIGCLTSISEVSIYFYL
                     HLTVVCYTIGMILSLGRLIFPNHSIFNKLKK"
BASE COUNT         1072 a          447 c          657 g         1152 t
ORIGIN      
        1 tattgcgggt ggattaactt gcgttggtgg tatgttattt aatggaaaat aattttgagg
       61 tgaaaaatgg ataatttttt agaattacag tttgaagaat tagtaaatat ttctggtgga
      121 aaaggaaata ttggatctgc tatcggaggg tgcttaggtg ggatgcttat agctgcagca
      181 ggaggtccaa taactggagg tgcggcagca tttgtatgtg tagcatctgg aattgcagct
      241 tatcaatgat atgattatag ttataatact cggtttaatt tgtctaatac tttcccaaat
      301 ttttttgaag gataaagagg taagagaaaa tgcaagtaaa gtaattttaa ttgtgatatt
      361 tgtttatgtc ttactaagta ctattacaaa ttaataatat taaaatgttg tgtaaacaca
      421 agagtagagt ttttgaatat tagtcaaata aactatcaag tgtgtcaaag catgctccga
      481 atcctttatg aatacgagct ccgaacttaa tattatagtc ctcgaaaata cttacaagac
      541 atcgttctaa ggcttcttca tttgggaaaa ccactctctt cttgttttgt cgcttaattt
      601 ctttattgag tgattcaatc aagtttgtag agtaaatgct agaccaaatg tgatgtggga
      661 attgatagaa agtaaggaga ttttccgtcg tttcaagtga tgccatgacc tttttataac
      721 gaggcttcca ttcagaaaca agtggtgacc atacatgcgc tcaataatgt cactgatttc
      781 gcgtgtcgta acgccagtct gatagagttt gatcaccatc tcttccaagt ggtcatctcg
      841 tctagcataa gatggtaata aaactggtga aaactcgccg tttcgatctc ttgggatgat
      901 taaattgact aagccatact ttgtttcaaa ctgacgagaa taagtcccat tacggctatt
      961 acctgtgttg taaccttctt tttcataagg ttcataacca agaaaagctg atagttcaac
     1021 ttgcaagagg tcattcatag ctatttctaa agaggagcga aagaattcat caatatcttg
     1081 tttttgtgct aggaagttaa gtaattctgt ggtaaactga gtcatgggaa taaatctctt
     1141 tctagtgaag tgtcgtaact ctactataca agatttattc ctttttgtgt gtttacacaa
     1201 gatattttac actaccatca aaaatcttaa aaggtattta taaaagcatg aatggtatca
     1261 tttaaacttc ttaattaatt aactattgtc acagcgtaag tgtagagagg ataaaaagac
     1321 atttcatgat gaaaaatagc cttttaagat tttgaaacca tgatactgtt ctttatgata
     1381 ttctgtacta gctcgaggtt gcaacgagac aaatttaaga attatgaaaa gaagttattc
     1441 gatatggaga taaagaaact ggaaacattt caccaaatga ctatagaaaa gcttgccaag
     1501 gttgagggtg gtaagaataa ttggcaggca aatgtcagtg gggttatcgc tgcaggtagt
     1561 gctggagctg ctataggttt tccagtttgc ggtgtagcct gtggttatat tggagctaaa
     1621 acagctatta ctctttgggc tggtgtaaca ggagctacag gcggcttcta gaggaaagaa
     1681 aggatgacaa caatgaagga attaacaatt aatgacatgg ctagtataag tggaggaaac
     1741 gctccaggag atgctgtaat tggtggtctt ggaggcttag cttctggatt gaaattttgt
     1801 aaactgccac atccagtatt ggcaggtgga tgtgttgtag gatttacagt tggtggagca
     1861 tatttgggat atacagcaaa ttaaatgatc tatacgattt ttattattat gaatgcgtct
     1921 ataatgtttt taatcattgt tgatgccatt cataaaaaaa tgttgataaa tctataccat
     1981 atttagtgtt tttaattttc aatcaattat ccctttcgga aaaatcggta aacatgttat
     2041 ctatcgtagc tttggtagcg tcattatttg tttttatcga taaaagaaaa tagtgattat
     2101 gccaatgaat ttagatatca ctcttagctt tttaaaatac aaaagagtga aattagaatg
     2161 aaaaagactt caaaaatatg gaagtgctaa aaaaatggtc tgactatcat aaatggaggc
     2221 ggaaaagacg gagcaaatat ctttttgaca gggatggcag gtgctgcgca gggagtgaca
     2281 gtttgtgctc agacaggcgt atttatccct tggcaaggtt atattttgtg tggagcagct
     2341 ggtgctgcta caaatattat ctggcctcac taaatatata aatgactatc tatcactgat
     2401 atataagtag tagaggagtg gtatgaaaat tttagatatt atttttaacc tatatgatag
     2461 aaagatgata tttctagaaa atgttgaaaa gctgggaggt tacattgtcc cttttaccct
     2521 tatcatcttg agtgtagcct acaactttag gcacccttat cctatttggg ctgctgtact
     2581 aggaggtata tcccttattg tgatctttat ttattttata cttattgttt atctatattt
     2641 gcgttataga tacttggtgt ggaaaaaaat accagaaatt aagattaatt ctactgagct
     2701 atcatgcaat cacatttaag gggaaaatgg attacttata caatatcagt acttatgata
     2761 tttaacttta gagactaaag agttaaaagc aaaatacgta ttgaaaattg gttaaaaaag
     2821 ttataactgt ctctgataac aggaataata atttgttcgg ttatatttgc taccgataga
     2881 gtagaggagg tgaagatatg cgtaatatat taagattttt aggtattgtt attatttctg
     2941 cagtgattct atttagtata ggtagtttct acgatttacc attaatgaaa aatatacaac
     3001 ttatctgttg gagttttatc cttgatttat tcgtttttgt ctacaaacaa agacaaacga
     3061 cagaagtgct cacatggtat caagttgtta agcaattttg gttatttatt aagtgtacaa
     3121 ttcttattcc taccttaatt gcttttatta taataatagg atgtttgacg agtatatcag
     3181 aggtatcaat ttacttttat ttacacctta ctgttgtttg ctatacaata ggaatgattt
     3241 tatcattagg tcgtcttatt tttcctaatc actctatatt taataaactt aaaaagtgaa
     3301 atgaatcata tttaaagttt gtttttaa
//
LOCUS       DATWEK010000076         3322 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.076, whole genome shotgun sequence.
ACCESSION   DATWEK010000076 DATWEK010000000
VERSION     DATWEK010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3322
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.076"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            12..1661
                     /locus_tag="VCR92_001806"
     CDS             12..1661
                     /locus_tag="VCR92_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_115157939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-like surface protein"
                     /protein_id="HEP4268843.1"
                     /translation="MFRRSKNNSYDTSQTKQRFSIKKFKFGAASVLIGLSFLGGVTQG
                     NLNIFEESIVAASTIPGSAATLNTSITKNIQNGNAYIDLYDVKNGLIDPQNLIVLNPS
                     SYSANYYIKQGAKYYSNPSEITTTGSATITFNILDETGNPHKKADGQIDIVSVNLTIY
                     DSTALRNRIDEVINNANDPKWSDGSRDEVLTGLEKIKKDIDNNPKTQIDIDNKINEVN
                     EIEKLLVVSLPDKIKYSPEAKHRTVEQHAELDAKDSIANTDELPSNSTYNWKNGHKPD
                     TSTSGEKDGIVEVHYPDGTVDDVNVKVTVTSKKTDNTAPTLTVTPEQQTVKVDEDITF
                     TVTVEDENEVELGLDDLKAKYENDIIGARVKIKYLTKEPNKKVMEVTIMKATLADKGA
                     ITFTAKDKAGNQAEPKTVTINVLPLKDSNEPKGKDQTVKVGETPKAEDSIGNLSDLPK
                     GTTVAFEAPVDTATPGDKPAKVVVTYPDGSKDTVDVTVKVVDPRTDADKNDPAGKNQQ
                     VKGKGNKLPATGENATPFFNVAALTIISSVGLLSVSKKKED"
     gene            complement(2167..2316)
                     /locus_tag="VCR92_001807"
                     /pseudo
     CDS             complement(2167..2316)
                     /locus_tag="VCR92_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            2373..2666
                     /locus_tag="VCR92_001808"
     CDS             2373..2666
                     /locus_tag="VCR92_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEP4268844.1"
                     /translation="MSTVAVRVDDQLKDDATELFQSLGLDMSTAVKMFLIQSVKTQSI
                     PFEIKNQSSVSDEEFQNLVETKLKGIRVKASDPESVNAFFGDEDFSEYEEYFK"
     gene            2663..3001
                     /locus_tag="VCR92_001809"
     CDS             2663..3001
                     /locus_tag="VCR92_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268845.1"
                     /translation="MSDIEVYSVLVSRIEYSDGTGSKVRPAVVVKFNDEVIKTLRLTT
                     KYENKSDNIKSQYLEVIDWAKANLKRRSWIDTIQYYDLEDKGFNIKIIGKLSDRDIER
                     LKDFLRAKEV"
     gene            3004..>3322
                     /locus_tag="VCR92_001810"
     CDS             3004..>3322
                     /locus_tag="VCR92_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268846.1"
                     /translation="MKKKLVGFIVLALSTIILVACSNDSLEGEYYWINDARNQHMATI
                     KGDKGYVESEGGYSIKIDSELKIIESKFGSEKYSYKDGKLTTNFTGVESDFYKKGSKA
                     CEEA"
BASE COUNT         1225 a          433 c          635 g         1029 t
ORIGIN      
        1 aggagaatat tatgtttaga aggtctaaaa ataacagtta tgatacttca cagacgaaac
       61 aacggttttc aattaagaag ttcaagtttg gtgcagcttc tgtactaatt ggtcttagtt
      121 ttttgggtgg ggttacacaa ggtaatctta atatttttga agagtcaata gttgctgcat
      181 ctacaattcc agggagtgca gcgaccttaa atacaagcat cactaaaaat atacaaaacg
      241 gaaatgctta catagattta tatgatgtaa agaatggatt gattgatcct caaaacctca
      301 ttgtattaaa tccatcaagc tattcagcaa attattatat caaacaaggt gctaaatatt
      361 atagtaatcc gagtgaaatt acaacaactg gttcagcaac tattactttt aatatacttg
      421 atgaaactgg aaatccacat aaaaaagctg atggacaaat tgatatagtt agtgtgaatt
      481 taactatata tgattctaca gctttaagaa ataggataga tgaagtaata aataatgcaa
      541 atgatcctaa gtggagtgat gggagtcgtg atgaagtctt aactggatta gaaaaaataa
      601 aaaaagatat tgataataat ccaaaaacac aaatagatat tgataataaa attaatgaag
      661 tcaatgaaat agagaaattg ttagttgtat cgctaccaga taaaattaag tattcgccag
      721 aggctaagca taggactgtt gaacaacacg cggaattaga tgcaaaagat agcattgcaa
      781 atacagatga attgccatca aattcaacgt ataactggaa aaatggtcat aaaccagaca
      841 cctcaacatc aggtgaaaaa gacggaattg ttgaagttca ctatccagat ggtactgttg
      901 atgatgtgaa tgttaaagta accgttacat cgaaaaaaac tgataataca gctccaacat
      961 taaccgtcac tccagagcaa cagactgtta aagtggatga agatattacc tttacggtta
     1021 cagttgaaga cgaaaatgaa gttgaactag gtttagatga tcttaaagct aagtatgaaa
     1081 atgatatcat tggagctcgt gttaaaatta agtatcttac taaagaacct aataagaaag
     1141 tcatggaagt gacaattatg aaagctactt tagcagataa gggcgcaatt acctttactg
     1201 caaaagataa agcaggtaat caagcagaac ctaagacagt taccatcaat gttcttccgc
     1261 ttaaggatag caacgaacca aaaggtaagg accaaacggt caaagtagga gaaacaccga
     1321 aggcagaaga ttctattggt aacttatcag atcttccgaa aggtacaaca gtagcctttg
     1381 aagctccagt tgatacagca acaccgggag acaaaccagc aaaagttgtt gtgacttacc
     1441 cagatggttc aaaagatact gtagatgtga ctgttaaggt tgtcgatcca cgtacagatg
     1501 ccgataagaa tgatccagca ggtaaaaatc agcaagtcaa aggtaaagga aataaactac
     1561 cagcaacagg tgagaatgca actccattct ttaatgttgc agctttgaca attatatcat
     1621 cagttggttt attatctgtt tctaagaaaa aagaggatta atcttttgac ctaaaatgtc
     1681 actaaacttt tcaccattta ttggtgtgaa cacattaata aagttatgta tctctctcca
     1741 acaaacttaa ttaaagtatt tcaatttttc gagtttaatt cttgaaaaag cctatcgaga
     1801 ttattaattt cgataggctt ttgattttgt gtaagcgtcc aataacgagg tatcttccat
     1861 tttcttccct attccgtaag catccaatat accttgttat tggacgctta ctataaaact
     1921 gaagaaatga tcctatttag ttgaaatttg taaatgaagt gtatcattag agcctaagat
     1981 gttaatccta ggctctcttt tgttgattta aaatttttag gtgtaatcaa atgtaaggtt
     2041 agatgcaaaa ttttctaaaa tgactgtttg tcttttcaag taattaaatg tatttaaggg
     2101 gaatttataa aaataaaagg agtgtgtcaa taatgttgtg taaacacact ggcaaagctg
     2161 ggattgttaa tcaaataggc tttcaagtgt gtctgtacaa tgaccaaaac ctttgtggac
     2221 tcgttgttct tgcttgaagt tgtaatcatt aaatagtgtg actagacagt gttctagggt
     2281 ctcttcactg ggaaatacga ttttcttttt tgtttgcgtt gtattgcagt tagtgataca
     2341 atggttatac aaaaatgatt tgaggtgata ttatgtcaac agtagcagta agagttgatg
     2401 atcaattaaa agatgatgct acagaacttt ttcaatcctt agggttggat atgagtacag
     2461 cagtaaaaat gtttttgatt cagtctgtta aaactcaaag tattcctttt gaaataaaaa
     2521 atcaatcatc tgtttctgat gaagaatttc aaaatttggt agaaacaaaa ttaaaaggaa
     2581 tacgagttaa ggctagtgat ccagaaagtg taaatgcgtt ttttggagat gaagattttt
     2641 cagaatatga ggaatatttt aaatgagtga tattgaggta tattctgtat tagtttcacg
     2701 tattgaatat tctgatggta caggttcaaa ggttcgtcct gctgtagtag tcaaatttaa
     2761 tgatgaagta ataaaaactt taagattaac tactaaatat gaaaataagt ctgacaatat
     2821 aaaaagtcag tatttagaag ttattgattg ggcaaaagca aatttaaaaa ggcgttcatg
     2881 gattgataca attcagtact atgatttaga ggacaaggga ttcaatatta aaattattgg
     2941 taagttaagt gatagagata ttgaaagatt aaaagatttt ctcagagcaa aggaagttta
     3001 gttatgaaaa agaaattagt tggttttatt gttctagctt tatctacaat aattttggta
     3061 gcatgttcta atgattcact tgaaggtgaa tattattgga ttaatgatgc tagaaatcag
     3121 catatggcta caattaaagg cgataagggt tatgttgaat cagaaggcgg ttattccata
     3181 aaaattgatt cagagttaaa aattattgaa agtaaatttg gttctgaaaa atatagttat
     3241 aaggatggaa aattgacaac aaattttact ggtgtagaaa gtgattttta taaaaaggga
     3301 tcaaaagctt gtgaggaagc at
//
LOCUS       DATWEK010000077         3173 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.077, whole genome shotgun sequence.
ACCESSION   DATWEK010000077 DATWEK010000000
VERSION     DATWEK010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3173
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.077"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..838
                     /locus_tag="VCR92_001811"
     CDS             <1..838
                     /locus_tag="VCR92_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEP4268847.1"
                     /translation="LGNAGQVSQVESGKRPITSSMLVYLNALTASSYTYIVFGELDEF
                     IENLFHYFFSSILYRDLEAVDENLYSFMSDDLISIQSSCLSIAKTFANFNIQRKRFMI
                     STETEMDTFHKKDDIDVWVGGKSYNPARSFRNNPINELTVIDFEEMADILLLMLRDNL
                     IRSFEINVCNTLFELDKNGEPTTFNLDKIDSIINKWWSENVSTEIIPNLIKKLRENPL
                     FNIGFMVNDILERMYKEDIPKSYLTSVPLVISKKARSTLSIKSNGSQKIDKSKFAQIL
                     SL"
     gene            904..1656
                     /locus_tag="VCR92_001812"
     CDS             904..1656
                     /locus_tag="VCR92_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEP4268848.1"
                     /translation="MAIPDLDKFSSNLQQGKIPVIKHFELNLDKGSHWAIAGNSGSGK
                     PYALTYFLSVLKPMSGLIIIDPKFDTPSQWARENKIAVIHPVENHSKSDFVSQVNEQL
                     NQCATLIQKRQAILYDNPNHQFTHLTIVIDEVLALSEGVNKNIKEAFFSLLSQIALLG
                     HATKIHLFLGSQRFDHNTIPISVREQLNVLLQIGNINQKTTQFLFPDLDPEGIVIPTG
                     HGTGIIQVVDNEHSYQVLPLLCPTYYTKRGIL"
     gene            1653..2255
                     /locus_tag="VCR92_001813"
     CDS             1653..2255
                     /locus_tag="VCR92_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268849.1"
                     /translation="MTTKTYFMRSFNLILYLLLIAPICYVFGWLFNLVSVQLSTVTFV
                     NLDTVKNVTDTISSVCYGFALISLLLALLSGLKMIQRLNTDSLGNYCQSIYRTFLLRH
                     FLFQRERVQKVSNFEHQTVTTINPIHNGFNRAVRKCIVDIRKDAITVFLKVPRDQQGQ
                     KILKDTGVQLKEEIVIQHTDYYFSSPVRVRNQLWFIGQKR"
     gene            complement(2731..3012)
                     /locus_tag="VCR92_001814"
     CDS             complement(2731..3012)
                     /locus_tag="VCR92_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEP4268850.1"
                     /translation="MLSKSLQVPLEQLIAEDIPKMTLIIKDEEIKQCDRNTHIMLFGT
                     LLIAISIYPIMSWLGWWGYGPVAILWLIIMRIALRIERFKKTYDVQTYR"
     gene            complement(3019..3069)
                     /locus_tag="VCR92_001815"
                     /pseudo
     CDS             complement(3019..3069)
                     /locus_tag="VCR92_001815"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
BASE COUNT         1042 a          595 c          523 g         1013 t
ORIGIN      
        1 actaggcaat gcaggtcaag ttagtcaagt tgaaagtggt aagcgaccaa ttacgagttc
       61 gatgttagtt tatttaaatg ctctaaccgc ttcgagctat acgtatatcg tttttggaga
      121 gttagatgag tttattgaga atctgtttca ttattttttc agttctattt tatatagaga
      181 tttagaggct gtagatgaaa acctatattc tttcatgagt gatgatttaa tttcaatcca
      241 atcaagttgt ctaagtattg ccaagacatt tgcaaatttc aatattcaaa gaaaaagatt
      301 tatgatttct actgaaactg aaatggatac ttttcacaag aaagatgaca ttgacgtatg
      361 ggttggtgga aaaagttata accccgctag gagttttagg aataatccaa taaatgaatt
      421 aactgttatt gattttgaag aaatggctga tattcttttg ttgatgttga gagataatct
      481 aattaggtcg tttgaaatta atgtctgcaa cacactgttc gaattagata aaaatggtga
      541 accgacaaca tttaatctag ataaaattga ctcaataatc aataagtggt ggtctgagaa
      601 tgtctcaaca gagataatac ccaacctcat aaaaaaactt agagaaaatc ccttgtttaa
      661 tatcggattt atggtaaatg atatattaga acgaatgtat aaagaggaca taccaaagtc
      721 ttaccttact tctgttccat tagttatttc caaaaaagca aggtcaactt tatcgattaa
      781 gtcaaacgga agtcaaaaaa tagataaatc aaaatttgca cagattttgt ccctttagag
      841 acggatgact tacacattca acgtggatta ttcttccctt ggagaaaggg gatttcagaa
      901 cgcttggcga ttcctgattt agataaattt tcatctaact tacaacaggg gaaaattcct
      961 gtcataaagc acttcgaact caatttagat aaggggagtc actgggctat tgctggaaat
     1021 tcaggttctg ggaaaccgta cgctctcact tacttcttga gtgtcctgaa acctatgtcc
     1081 ggcctaatta tcattgaccc aaaattcgat acccctagcc aatgggcaag agaaaataaa
     1141 attgccgtta tccacccagt agaaaaccat tcaaaatctg atttcgtttc acaagtcaat
     1201 gaacaattaa accagtgtgc aactctcatt cagaaacgac aagctatctt gtatgataat
     1261 cccaatcatc aatttaccca tctaactatt gttattgatg aagtcctcgc tctatcagag
     1321 ggagtcaata agaatatcaa agaagctttt ttctccctac tatcacaaat tgccttgttg
     1381 ggacatgcta ctaaaatcca tctattcttg ggaagccagc gttttgacca taacactatt
     1441 cccatttcag tgagggaaca gctaaacgta ttattgcaaa ttggaaatat caatcagaaa
     1501 accactcaat tcttatttcc agacctagat ccagagggga ttgtcattcc aacaggacac
     1561 ggaacaggta tcattcaagt tgtcgataat gaacactcct atcaagttct acccttactc
     1621 tgtccaacct actatactaa gcgaggtatc ctatgaccac taaaacctac ttcatgagaa
     1681 gcttcaatct catattatac ttactgctta ttgctccaat ctgctatgtg ttcggttggc
     1741 tgttcaatct tgtttcagtt caattatcta ccgtcacatt tgtcaatctg gatacggtta
     1801 aaaacgttac tgataccatt agttctgtat gttatggatt cgctcttatt tctttacttc
     1861 tagccttatt atctggatta aagatgatac aacgcttgaa tacagatagc cttgggaact
     1921 actgccaatc tatttatcgc acctttctat taagacactt ccttttccag cgtgaacgag
     1981 tacagaaggt aagcaacttt gaacaccaga ccgttaccac tatcaatcca atccataacg
     2041 ggtttaaccg agctgtacgt aagtgtatcg tagatatacg aaaagatgcc attactgtat
     2101 ttctaaaagt tcctagagac caacaggggc aaaaaatcct aaaggatacg ggagtacaac
     2161 tgaaagaaga gattgtcatc caacacacag actattattt ctcttctcct gttcgagttc
     2221 gtaaccaatt gtggtttatt ggtcaaaagc gttaattcct tggggctgtg gcttgcgtta
     2281 agcaaaagcc agacagcccc ttttttatat tcttatctat catgacctat tggggttact
     2341 acgacaacga aagttagaag ctgtgggtat ttatttatct tgaaaagatt gctgaactaa
     2401 cgcaataact actctaccat tcactctacc ttttattaag caactatcaa taaatattga
     2461 tacaataagg tttataacag ctaaaataga aaatacttaa cctttacaga agtaaaataa
     2521 ttgagatgag aaaagcctat gaaatgaacg tttcaaaggc ttttttcgtg tttaaaaaaa
     2581 caaatgaaaa aacaaaatag agagtagggt tattaacact gtcaatcctg tgtacgcaat
     2641 aacaatccat gctttttgat aaggatattt tgctttttct ttaatcttat caatctgatc
     2701 taagctctca ccctttgcta taacttcaag ttatcggtaa gtctgaacat catatgtctt
     2761 tttaaatcgc tcaattctta aggcgatacg catgattatc aaccataaga tagcaaccgg
     2821 accatatccc caccaaccta accaagacat tataggataa atactgatag caattaggag
     2881 tgtcccaaat aacataatat gcgtattcct atcacattgt ttaatctcct catccttaat
     2941 aattaaagtc atttttggga tatcttctgc tattagttgc tctaaaggaa cctgtaagga
     3001 cttacttaac atcaaaagat tttgcaggtc tggatagctt ttaccgtttt cccagtttga
     3061 gatagtcttc ttgaaacata catcatttca gcaagctctt cttgtgacat ctgtaatttt
     3121 tttcaataat aagataactg gtttttaaag cccataataa atctcctttt taa
//
LOCUS       DATWEK010000078         3108 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.078, whole genome shotgun sequence.
ACCESSION   DATWEK010000078 DATWEK010000000
VERSION     DATWEK010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3108
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.078"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            326..1444
                     /locus_tag="VCR92_001816"
     CDS             326..1444
                     /locus_tag="VCR92_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015968565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268851.1"
                     /translation="MGIIAAGQITVVDLSDAPVLNAFITANRPTTQVYSQTSGSYNPS
                     YASTPQTLTLNLTKAGSTASIVGGVSGLRWYVVDGATKTEITSKVNTDNEFVSGTNNE
                     NLTTKLNIDTDRGSKRYEAAGIWKDPITGLDVQFSADIDLFLTQVGKEAQVLNVYAGN
                     GNTFRNNLPASLTVNADLYRGNVLTNDKKIFKFFYQDTSITGSTVAGYDPDGGIGWHL
                     CNNGSSATEGQTPNVKPTEPTTGQGVLTVSPSKVTNAQSFKVVCINRIDNTKTTGLCT
                     LLDMSDPYSLMLDSSAGNIFKNRQGSTALKARLYRNGEELDANGTGKTYKWSKYDKNG
                     VMDVNFGGGGNAYKTGKTINVNATEIVAKASFKCEVWE"
     gene            1459..1662
                     /locus_tag="VCR92_001817"
     CDS             1459..1662
                     /locus_tag="VCR92_001817"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268852.1"
                     /translation="MIKADIKIAEQRQIVDVPVETKSEAIRVLWNTYGLGIDIKRWIE
                     EEKDEQTDSNEPTDSDESDGKGD"
     gene            1601..>3108
                     /locus_tag="VCR92_001818"
     CDS             1601..>3108
                     /locus_tag="VCR92_001818"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268853.1"
                     /translation="MSKLIATSQLTLMNLTEKAIERTEVTFWHGLSATKHPLGVYDCG
                     GRDHAFANEFDVVSGKKYTVRVIAQKTKGTINLKGGIWYTERTSGYQFDGLAALTLVG
                     ELSEDGLGIWERTLTVPNGKTKGRVYVQLEQSSTSGFSTAYRVYDAQVFDENGQPLVT
                     DQNNFGALTSPMAAPDGTYIWKRTITHYTDGTNDTVWEYSGVGEKGNTGANGQTSHVH
                     FAFADNATGGGFSLTTPKAYMGWYADFNEAASTDPTKYRWSKWKGDQGLPGKPGADGK
                     TSYFHMAYADSADGRTGFSFKESGQQYQGYYTDFVQANSTDPTKYTWMDRRAGIEVDF
                     RNLLSKTNRGKTNWSWIISSGGTTAEDYNVDGINAVKLTRTSDASFSWNYIQYQGLLR
                     NLIEPNTKYTLSFDIKPSVDVTFTASLRRGDSGAPLTNSTTMNKATANQWNKVSCVLT
                     SKTTLPDDLSQVVYLQGMPVAKGNYLIIKNIKLGKGNVPTPWIPALEDTQDQ"
BASE COUNT         1010 a          614 c          731 g          753 t
ORIGIN      
        1 gaaatcacgc tagctaatat ggtcgagcag attgatttag tcatcctgac gtcaaacggc
       61 tatacgttca aaaacaacaa catagcgagc acactgacag ccactctatg gcgtgggaat
      121 aaggaaatcg acaaagatgg cactgagttc agctacgttt ggaagaaagt caatagcgat
      181 gagacgccgg acgaacattg gaacgctgac cattcgtact ctcaaaaatc aataagaatc
      241 acagaagctg acgtatttag acgagccaca ttctcgtgcg aagtccaata tgtcggcaaa
      301 cgagtttaaa aggagaaaaa atattatggg aattatcgcg gcaggacaga taacagtcgt
      361 agacttgtca gacgcgcctg tactgaatgc gtttatcaca gctaatagac ctacaacgca
      421 agtttatagt caaacgtctg gaagttataa tccatcttat gcctcaacac ctcaaacgtt
      481 aacacttaac ttaactaaag ctggctcaac agcaagcatt gtcggcggtg ttagtggctt
      541 acgctggtat gttgtggacg gtgccacaaa aacagaaata acgtcaaaag ttaatactga
      601 taacgagttt gtttcaggca ctaacaatga gaacttgacc actaagctaa atattgacac
      661 agacagaggc tcgaagcgct atgaggcagc tggaatttgg aaagacccaa tcactggtct
      721 ggacgttcag ttcagtgctg acattgacct gtttttaaca caggttggga aagaggcaca
      781 ggttttgaac gtttatgctg gaaatggtaa tacgttccga aacaacttac ctgccagcct
      841 cacagtcaac gcagaccttt atcgtgggaa tgtgttaacg aatgataaaa aaatattcaa
      901 gttcttttac caagacacga gcattactgg cagcacagta gctggttatg atcctgacgg
      961 cggcattgga tggcatctat gcaataatgg cagcagcgcc actgaaggtc aaacgccaaa
     1021 cgtgaagccg actgagccaa cgactgggca aggcgtcctc actgtatcgc caagcaaagt
     1081 aactaacgca caaagtttca aagtcgtatg cattaaccga atcgacaaca caaaaacaac
     1141 aggtctatgc actttgttag atatgtcaga tccatacagc ttaatgcttg attcaagtgc
     1201 cggaaacatt ttcaaaaacc gtcaagggtc aactgcactg aaggcgcgtc tttatcgaaa
     1261 cggcgaagag cttgacgcaa acggcacagg taagacttac aagtggtcga aatatgacaa
     1321 aaacggtgtt atggatgtca attttggcgg tggaggcaat gcatacaaaa ctggcaaaac
     1381 aattaatgtt aacgctactg aaattgtagc taaagctagc ttcaaatgtg aagtctggga
     1441 atagggggtg tataggatat gattaaagca gatattaaaa ttgctgaaca gcgtcaaatt
     1501 gtcgatgtgc ctgttgaaac aaagtcagaa gcaattcgtg tgctttggaa tacatatggt
     1561 ctagggattg atatcaaacg ctggattgag gaggaaaaag atgagcaaac tgatagcaac
     1621 gagccaactg actctgatga atctgacgga aaaggcgatt gagcgaactg aggtaacgtt
     1681 ttggcacggc ttatccgcaa ctaaacaccc gctaggggtt tatgattgcg gtggtcgtga
     1741 ccatgctttt gctaatgagt ttgacgttgt cagcggaaag aaatatacag ttagggttat
     1801 tgctcaaaaa acaaaaggga ctattaatct taaaggcggt atctggtaca cggaaagaac
     1861 gtctggttat caatttgatg gtctagcagc ccttactctg gtaggggaac ttagtgaaga
     1921 tgggctagga atttgggaaa gaactttaac agtcccaaat ggaaaaacca agggtagagt
     1981 ttatgttcag cttgaacagt catcgactag tggattttca accgcttatc gtgtatacga
     2041 cgctcaggta tttgatgaaa acgggcaacc ccttgtgact gaccagaata attttggtgc
     2101 tttaacaagt cctatggcag cccctgatgg cacatacatc tggaagcgta ctatcacaca
     2161 ctacactgac ggtacaaatg atactgtctg ggaatatagc ggtgttggcg agaagggtaa
     2221 tacaggggcg aacggtcaaa cctcgcacgt acactttgcc ttcgccgaca acgcaactgg
     2281 tggcggattt agcttaacta caccaaaagc atacatgggt tggtacgctg attttaacga
     2341 ggcggcaagt acagacccga ctaagtatag gtggagcaag tggaaaggcg accaaggctt
     2401 gccaggaaaa ccaggtgctg acgggaaaac gtcctatttc cacatggcct atgcagattc
     2461 cgcagatggc agaactggtt ttagttttaa agagtctggt cagcagtatc aaggctatta
     2521 cacagacttc gtacaagcaa acagtacaga cccaactaaa tacacttgga tggatagacg
     2581 ggctgggatt gaagttgact ttagaaactt actttctaaa accaaccgag ggaagacaaa
     2641 ttggtcatgg attatttcga gcggtggaac gactgcagaa gattataatg ttgatggaat
     2701 caatgctgtt aaattaacgc gtacgtcaga tgcttcgttt tcgtggaatt acattcaata
     2761 tcaggggtta ctgagaaatc ttattgaacc aaatacaaaa tatacacttt cgtttgatat
     2821 aaaaccaagc gttgacgtga ctttcacagc gtcattgagg cgtggcgata gcggcgcccc
     2881 actcacaaat agcacaacaa tgaataaagc cacagctaat cagtggaata aagtctcttg
     2941 tgttttaacg tcaaaaacaa cattgccaga tgatttgtcg caagttgtct atttacaagg
     3001 tatgcctgtt gcaaaaggca attatttgat aattaaaaac atcaaacttg gaaaaggtaa
     3061 cgttccaaca ccgtggatac cagctttaga agatacacaa gaccaaat
//
LOCUS       DATWEK010000079         3086 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.079, whole genome shotgun sequence.
ACCESSION   DATWEK010000079 DATWEK010000000
VERSION     DATWEK010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3086
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.079"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            821..1954
                     /locus_tag="VCR92_001819"
                     /pseudo
     CDS             821..1954
                     /locus_tag="VCR92_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088025.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            2216..2521
                     /locus_tag="VCR92_001820"
     CDS             2216..2521
                     /locus_tag="VCR92_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HEP4268854.1"
                     /translation="MEKSTLKLKPDFIGKAWYEKLGNAPRRIDGEAGQFQRHIVSNEK
                     HGVFHVITPALAQVFKTDDVVEIDGEAIFFEDRALNGNSVAPALNVRATGLKLAGGK"
     gene            2524..2979
                     /locus_tag="VCR92_001821"
     CDS             2524..2979
                     /locus_tag="VCR92_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEP4268855.1"
                     /translation="MAKVGLNFGEKIQIVDKSYRVLNDGLVDLKEIFGDLSFRSFEET
                     DLIYEDDMTQPRRQDGSYPQIPTGESRGLVVGIFSPVQQQTEFVTLVDMSLAEFEALQ
                     LKYREPVELEGIIVTYSSVGSNQFKLFASKIKRSVSQKVANEGNHKQEK"
BASE COUNT          997 a          567 c          660 g          862 t
ORIGIN      
        1 aacagatgat gttccaaact tagagaagga aaagccggta ccaccaactc cagttaaacc
       61 agaggcagtt aaacctgttt tagaacaaga aaaaccagtc ccagaagctc ctcaaaagcc
      121 aacagatgat gttccaaact tagagaagga aaaaccagta ccaccaaccc cagttgaacc
      181 tgaagcaatt aagccagatc tccaaagctt tacgccagag gtttatgacc cgattaaacc
      241 agttgtgaaa ccccatgtca ccgttcctga aaaggtcgtc tatgaggtta tggttcatcc
      301 tgttcaagtg aaacaaacgc caacaaatgt taagtctgtt actaatagtg atcaggttaa
      361 tatcgatgga caactggtac caaaaggatc aacggtaacg tgggagcttg ttaatacttc
      421 tctcaaagct ggtcgtcagg acatcacaag ctatgaacta actgatccac taccagatgg
      481 ttttgagtta gatgttaccg ccacacaaac cctttctcct gaatgggtga taacaacgga
      541 tgaagcaggc aaggttagtc ttaaggcttc tcaatccctt ttggctcact tcaatgctaa
      601 acgtgatcaa gatgtagaag tccctaaggt atcactggtt ggtcgtttac tgaatgatgc
      661 ggggacttat cacaatacct ttaagacggt ggtcactact ccaactggta gctacacggt
      721 aatctctaac acaccagtga tctatacacc agggaacgat ccgaaaacac ctcgtaaccc
      781 aggaggagat aatccaacac cgcatgataa tctgattcag ccaactaaaa ccattgtgga
      841 cgacaagggt cagtccattg atgggaagtc tgtcttgcca aacagcacgc tgacttacgt
      901 ggctaagcaa gattttgatc agtacaaagg gatgacagct gccaaagaaa gtgtcatgaa
      961 aggctttatc tatgtcgatg attacaagga tgaagcgata gatggtcatt cactcgttgt
     1021 gaattccatt aaggccgcta acggagatga tgtaaccaat ctcttagaga tgcgccatgt
     1081 gttatctcaa gatacgcttg acgataagct aaaagcactc atcaaggcat caggcatttc
     1141 tccagtcggt gaattttaca tgtgggtagc taaagaccca gcagcctttt acaaagctta
     1201 tgttcaaaaa gggttagaca ttacctacaa cttgtccttt aaacttaaac aggactttaa
     1261 gaaaggtgac attactaacc aaacctacca aattgatttt ggaaacggat actacggtaa
     1321 tatcgtggta aaccatctgt ctgaactaac tgttcataag gatgttttcg ataaagaagg
     1381 tggtcaatca atcaatgctg gcactgttaa agttggtgat gaggtcacct atcgcttgga
     1441 aggttgggtt gttccgacta accgtggcta tgacttgaca gaatacaaat ttgtggatca
     1501 gcttcagcat acgcatgacc tctaccagaa agacaaggtc cttgcgacgg ttgatattac
     1561 tttatcagat ggtagtgtta tcactaaagg tactgactta gcgaaatata ctgagacagt
     1621 ttacaataag gaaacaggtc actatgaatt agcgttcaag caagacttct tagctaaggt
     1681 cgttcgttct agcgaatttg gtgcagatgc ttttgtggtt gttaaacgca tcaaagcagg
     1741 tgatgtggca aatgagtata ccttgtatgt caacggtaat cctgtgaagt ctaataaagt
     1801 caccactcat acgccagaac aacctcaacc tgtaactcct aaagcaccag ctttaccatc
     1861 cacaggagag caaggagtat ctatcttaac ggcgcttggg gccgctttac tctcactctt
     1921 aggttatgta gggcttaaaa agcgtcaaca gtaagttatt aatggataag ccatcaaagt
     1981 agattacttt gggtctatcc attctctcta gcaagtaact attaggggga tctcctttcc
     2041 cttcaaaaaa ctagccgaaa aagtttacta ttggttactt gttagggtga gtggatagat
     2101 cttggtttat cactagaata gtgaccgaaa agtcaaaaaa ctaagtggta aggctaggaa
     2161 ataattgata agacaatcct agccttttta ttttaaaaat gaaaagaggt aaattatgga
     2221 gaaatcaaca ttaaagttaa aaccagattt tattggtaaa gcatggtatg aaaaattagg
     2281 aaatgctccc cgtcggattg atggcgaagc agggcagttt cagcgtcata ttgtgtcgaa
     2341 tgaaaagcat ggggtttttc atgtgattac accggcttta gcccaagtat ttaaaacaga
     2401 tgatgtagtt gaaattgatg gtgaagctat cttttttgaa gatagagctt tgaatggtaa
     2461 tagtgtagca cctgcactta atgtacgtgc aacaggattg aaattagctg gaggtaaata
     2521 gtaatggcaa aagtaggttt aaattttgga gagaaaattc agattgtaga taaaagttat
     2581 cgcgtattaa atgatggttt agttgacttg aaagaaattt ttggtgactt atcatttcga
     2641 tcctttgaag aaacagattt aatttatgaa gatgatatga ctcaaccaag acgtcaagat
     2701 ggttcttacc cacaaattcc tacaggcgaa tcacgtggac ttgttgttgg tattttctca
     2761 ccagtgcagc aacaaacaga atttgttact ttggttgata tgagccttgc ggagtttgaa
     2821 gcgttgcagt tgaaatatcg tgagccagtt gaattagaag gtattatcgt gacttattct
     2881 tctgtaggaa gtaatcagtt taagttattt gcttccaaaa ttaaacgctc tgttagccaa
     2941 aaagtagcta atgaaggtaa tcataagcaa gaaaaataaa taataaggga gaggtaagat
     3001 gcgtttactg cctgaatata gagggattaa ggtaaaacca tatatgaggt atatgagtta
     3061 ttaccttttt tcttttctat ttattt
//
LOCUS       DATWEK010000080         3057 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.080, whole genome shotgun sequence.
ACCESSION   DATWEK010000080 DATWEK010000000
VERSION     DATWEK010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3057
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.080"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..307
                     /gene="tilS"
                     /locus_tag="VCR92_001822"
     CDS             <1..307
                     /gene="tilS"
                     /locus_tag="VCR92_001822"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEP4268856.1"
                     /translation="SFMPKSNEDQGQVSIPLFSLSSIKLRSRQSGDYISFGHFSKKIR
                     RLFIDEKFTIAERQNAIIGEQDEQIIFVLIGNKTYLRKACKHDIMLAKLYIDKLEKG"
     gene            312..854
                     /gene="hpt"
                     /locus_tag="VCR92_001823"
     CDS             312..854
                     /gene="hpt"
                     /locus_tag="VCR92_001823"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEP4268857.1"
                     /translation="MLEQDIQKILYSENDIIRKTKKLGEQLTKDYQEKNPLMIGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYHGGTSSSGEVKILKDVDTNIEGRDIIIVEDII
                     DTGRTLKYLRDMFKYRKANTIKIATLFDKPEGRVVKIEADYVCYNIPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            876..2855
                     /gene="ftsH"
                     /locus_tag="VCR92_001824"
     CDS             876..2855
                     /gene="ftsH"
                     /locus_tag="VCR92_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEP4268858.1"
                     /translation="MKNNKNNGFVKNSFIYILMIIVVITGFQFYLKGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIIEVKGKYEKPQKVTVNSGLSFLGGRASTQVTEFSSL
                     VLPSDTILKEMTAAADKNGTELTVKQESSSGTWITFLMSFLPIVIFAAFMMMMMNQGG
                     GGARGAMSFGKNKAKSQSKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKSLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNENIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLANDVNLKVVAQQTPGFV
                     GADLENVLNEAALVAARRNKIKIDASDIDEAEDRVIAGPSKKDRTISQKEREMVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDLKEQLAGLMGGR
                     VAEEIVFNAQTSGASNDFEQATQIARAMVTEYGMSEKLGPVQYEGNHAMMPGQISPEK
                     SYSAQTAQMIDDEVRELLNQARNQAADIINENRDTHKLIAEALLKYETLDAAQIKSIY
                     ETGKMPVDLETDDNEAHALSYDEIKNKMTESESAE"
BASE COUNT         1054 a          434 c          626 g          943 t
ORIGIN      
        1 ttcatttatg ccaaaaagta acgaagatca aggacaggta agtatacctt tatttagttt
       61 atcgtctatt aaattaagaa gtcgccaatc tggagattat atttcttttg gtcacttttc
      121 aaaaaaaata agacgtttat ttatagatga aaaattcaca atagctgaac gccaaaatgc
      181 tattattgga gagcaagatg agcagattat atttgtattg ataggtaata aaacttattt
      241 gagaaaagct tgtaaacatg atataatgtt ggctaaactg tatattgata aattagaaaa
      301 agggtgacag catgctcgag caagatattc aaaaaattct ttactctgaa aatgatatta
      361 ttcggaaaac taaaaaatta ggagaacaat taacaaaaga ttatcaagaa aaaaatccgc
      421 ttatgattgg tgtattaaaa ggatcagttc cttttatggc agaactaatg aaacacatcg
      481 atactcatgt tgaaattgat tttatggtag tatcaagtta tcatggcggt acatctagca
      541 gtggtgaagt taaaatttta aaagatgtag ataccaatat tgaaggaaga gatatcataa
      601 ttgttgaaga tattattgac accggtcgca ccttaaaata tttacgagat atgtttaagt
      661 accgtaaagc taatactatc aaaattgcaa cactgtttga taaacctgaa ggtcgtgttg
      721 ttaaaattga agcagattat gtttgttaca atattccaaa tgaatttatc gtaggctttg
      781 gtttagatta cgcagaaaat tatcgcaatc ttccttacgt aggtgtatta aaagaagaag
      841 tctattcaaa atagaaaaag gtcaatgttt actgtatgaa aaataataaa aataatggtt
      901 ttgttaaaaa ttcttttata tatatattga tgattattgt tgtcatcaca ggatttcaat
      961 tttatcttaa gggaaccagc acacaaagcc aacagattag ttattccaaa ttaattaaac
     1021 atcttaaggc tggagatata aaatctttaa gttatcagcc tagcggtagt attattgaag
     1081 ttaaagggaa atatgagaaa cctcaaaaag tgacagttaa ttcaggacta tcatttttag
     1141 gtggaagagc ttcaacacag gtaacagagt tctcatcttt agtattacct agtgatacca
     1201 tcttgaaaga aatgacagca gcagctgata aaaatggaac agagcttaca gttaagcagg
     1261 aaagttcaag tggtacttgg attaccttct taatgagctt tttacctatt gttatttttg
     1321 ctgctttcat gatgatgatg atgaatcaag gtggtggagg agctcgtggt gctatgagtt
     1381 tcggcaaaaa taaggcaaaa tctcaatcaa aaggcgatgt taaagtgaga tttacagacg
     1441 ttgctggtgc cgaagaagaa aaacaagaat tagtagaagt tgttgatttt ttgaaaaatc
     1501 ctaaaaaata taaatcacta ggagcacgga tcccagcggg agttcttcta gaggggcctc
     1561 caggtactgg taaaacatta ctagctaaag ctgtagcagg tgaagctgga gtgccatttt
     1621 tcagtatttc aggttcagat tttgtcgaaa tgtttgtcgg tgtaggtgct agtcgtgttc
     1681 gttctttatt tgaggatgct aaaaaagctg agcgtgcaat catctttatc gatgaaattg
     1741 acgctgtagg tcgtcgtcgt ggtgctggca tgggaggcgg taacgatgaa cgagaacaga
     1801 cccttaacca attactcatt gaaatggatg gttttgaggg taatgagaac attatcgtta
     1861 ttgctgcaac taaccgtagt gatgttttag atccagcttt actaagacca ggtcgttttg
     1921 atcgtaaggt tttagttggt cgccctgatg ttaaaggacg tgaagccatt ttacgtgttc
     1981 atgctaaaaa taaaccactt gcaaatgacg ttaatttgaa agtagtagcc caacagactc
     2041 caggttttgt aggtgctgat cttgaaaatg ttttaaatga agctgcgttg gttgctgctc
     2101 gcagaaataa aattaaaatt gacgctagtg atattgatga agctgaagat cgtgttattg
     2161 ctggaccatc aaagaaagat cgcactattt cgcaaaaaga gcgagaaatg gttgcttatc
     2221 acgaagctgg tcatactatt gttggtttag ttttatctaa tgcgcgtgta gttcacaagg
     2281 taactattgt acctcgtgga cgagcaggtg gttatatgat cgctcttcca aaagaagatc
     2341 aaatgcttct ttctaaagaa gatctgaaag agcaattagc aggattgatg ggtggtcgtg
     2401 ttgctgaaga aattgttttt aatgctcaaa catcaggtgc gtcaaatgac tttgagcaag
     2461 ctactcagat agcaagggcc atggttacgg aatatggtat gagtgaaaag cttggaccag
     2521 ttcaatatga aggtaaccat gcgatgatgc caggacagat ctctcctgaa aaatcttact
     2581 ctgcccaaac agctcaaatg attgatgatg aggttcgtga actcttaaat caagctcgta
     2641 atcaagcagc tgatatcatc aatgagaatc gagatactca taaattgatt gctgaagctc
     2701 ttctcaaata tgaaactcta gacgctgcac aaattaaatc aatttatgaa actggtaaaa
     2761 tgccagttga tttagaaact gatgataatg aagctcatgc gttatcttat gacgaaatta
     2821 aaaataaaat gacagaatct gaatctgcag aatgatataa aaaagctgaa cttatagatt
     2881 aagttcagct tttttatcaa cacaatatcc ttgtaaacgt tatgaattgt aataggtgcc
     2941 taattgctag aaatgagaag atgacatact tttttttctt tattacttaa agtgagaaag
     3001 actttggtat ttaaaactag aaaattgtta aagccatttg aaaaaatcta ttagtgt
//
LOCUS       DATWEK010000081         3030 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.081, whole genome shotgun sequence.
ACCESSION   DATWEK010000081 DATWEK010000000
VERSION     DATWEK010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3030
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.081"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..816
                     /locus_tag="VCR92_001825"
     CDS             <1..816
                     /locus_tag="VCR92_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEP4268859.1"
                     /translation="SKKATAREMCAPLQGRIVTMEGMTHTEQGVKVLALSDYGYGYAG
                     GCLGVHCGHYLTPFIIGVNELPEDPDYLKDLTPEQAEENARIQAKQRALERAIRNQKE
                     RLHIASQLGDDELITSERLKLRNLQGKMRAYVDQHDFLHRDYSRERLFSTQNSYEKNK
                     ILLGTKKKTLEKQREVKSAIIGMKTSNNIKIKDVSKHLVDRAVERKVETQTIIDALKN
                     PLEIKEIKYDEYGRPSQKFIGKDTSVVINPSTGNIATTHKTGKRIRRKYGFEK"
     gene            813..1043
                     /locus_tag="VCR92_001826"
     CDS             813..1043
                     /locus_tag="VCR92_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268860.1"
                     /translation="MKIVEILNEKQIAFVKECLPNFDLDKILQNGELNDDFAEALEDY
                     YQLKAFDNAYNITQKGKIAESIIDKFVDLNIW"
     gene            1204..1761
                     /locus_tag="VCR92_001827"
     CDS             1204..1761
                     /locus_tag="VCR92_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HEP4268861.1"
                     /translation="MPFTKDDLINLGLTDEQAKEVFTLHGKDLNETKSALDTITQERD
                     SLKNQLQNAETQIETLKADANTSAEQKEALDKLQAEYDKFKADAEANLAMTQKVNAIN
                     LALKDTNAHNPSTLMKFIDVDTVELDEDGKPKLDDIITGLKESDPYLFKADDDTPNPS
                     IFATGNPAAKDPTPDAFAQALGLTE"
     gene            1775..2647
                     /locus_tag="VCR92_001828"
     CDS             1775..2647
                     /locus_tag="VCR92_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268862.1"
                     /translation="MSINYITKHEGQFEKRLMQGSLTSILETPRVNWLGARSFELPII
                     SVTGYKTHTRSKGYNAGTVSNDKNVYTLGFDRDVEFFVDTADVDETNQELSAANISNT
                     FISEHATPEVDAYRFSKIATAAITGNHFKAEDSITPENVYSTLKAAILPMRKFGASNL
                     VMYVSSEVMDALERSKDFTRSIATTSPQGIDTRVTSLDGVQLIEVWDDARFKTKFDFT
                     TGFVKAEDGKDINFLIVAKTAVIAKAKFNSIYLFAPGQHTEGDGYLYQNRLYHDLFVL
                     KSQEDGIYVSHKSA"
     gene            2658..2837
                     /locus_tag="VCR92_001829"
     CDS             2658..2837
                     /locus_tag="VCR92_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268863.1"
                     /translation="MKKYFKENQVYTVQEGSELEVQLIADGFEVLELKQEVVEEVEEQ
                     EEKPKRTKKSKNEGE"
     gene            2837..>3030
                     /locus_tag="VCR92_001830"
     CDS             2837..>3030
                     /locus_tag="VCR92_001830"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268864.1"
                     /translation="MAKYKAAKNIFFKSLNKSVMVDETIELDKEYADHVNADLAKAFP
                     DVEKVLVPLEEEPESVPEEVS"
BASE COUNT         1083 a          525 c          601 g          821 t
ORIGIN      
        1 tcaaagaaag ccacagctag agaaatgtgt gcacctttgc agggtcgtat agtgacaatg
       61 gaaggcatga cacatacaga gcaaggtgtt aaggtacttg ctttgtctga ctacggatat
      121 ggttatgctg gtggttgttt gggtgtgcat tgtggacatt atttgacacc ttttattatt
      181 ggggtcaatg agctaccaga agacccagac tatctcaaag acttaacgcc cgaacaagca
      241 gaagagaatg cacgtataca agccaaacaa agagcacttg aacgtgctat cagaaaccaa
      301 aaagagcgcc tacacatcgc tagtcaactg ggagatgatg aacttatcac atctgaacgc
      361 ttaaaactta gaaacttaca aggaaagatg cgagcttatg ttgatcagca tgatttcttg
      421 catcgtgatt attcaaggga aaggttattt tcaactcaaa attcatacga aaaaaataaa
      481 atattgttag ggactaagaa gaaaacttta gagaagcaac gagaggtgaa aagtgctata
      541 ataggcatga aaacaagcaa caatataaaa attaaagacg tttcaaaaca tcttgttgat
      601 cgtgctgttg aacgaaaggt tgaaactcaa actatcattg atgctttaaa aaatcctctt
      661 gaaataaaag agattaaata tgatgagtat ggtagaccat ctcaaaaatt tatcggtaaa
      721 gatacatcag ttgttattaa tccatctaca gggaatattg caacaactca taagacagga
      781 aaaagaattc gcagaaagta tggttttgaa aaatgaaaat agttgaaatt ctaaacgaaa
      841 agcaaatagc ttttgttaaa gagtgcttac ctaattttga tttagataaa attttgcaaa
      901 acggtgagtt gaatgatgac tttgcagaag ctttggaaga ttattaccag ctcaaagcct
      961 ttgacaatgc atacaacatt acacaaaaag gtaaaatagc agaaagtatc attgataaat
     1021 ttgtagatct gaatatttgg taagttatct tacttatttg cacctagatt ttttctaggt
     1081 gctttttttg tgcgttcaaa acggtaaaaa gtccgctttg ttcaaaggta aactgaagaa
     1141 gtaaataaga ttttaccttt gtggtggggg ttagccacct acaaaaagga ctaggaggac
     1201 aaaatgccat ttacaaaaga tgaccttatc aatcttggat tgacagatga acaagctaaa
     1261 gaagttttta ctttgcatgg caaagatttg aatgaaacta aatcagcctt ggacactatc
     1321 acgcaagagc gagacagtct taaaaatcaa ttgcaaaatg ctgagacaca gattgaaaca
     1381 ttgaaagctg atgcgaatac aagtgccgaa caaaaagaag cgcttgataa attgcaagct
     1441 gaatatgaca agtttaaagc tgatgctgaa gcaaatcttg caatgacaca aaaggtcaat
     1501 gctatcaacc ttgcattgaa agatactaac gcacacaatc catcaacctt gatgaaattt
     1561 attgatgttg acactgttga gcttgacgaa gacggtaagc caaaactaga cgacatcatc
     1621 acaggattaa aggaaagtga cccttatctt ttcaaagcag acgatgacac acctaaccca
     1681 agtatttttg ctactggaaa tcccgcagca aaagacccaa caccagacgc ctttgcacag
     1741 gctttgggat tgactgaata aaaaggagga aatcatgtca attaactaca ttactaaaca
     1801 tgaggggcaa tttgaaaaac gccttatgca aggttcttta acatcaatcc ttgaaacccc
     1861 tagagtaaat tggcttggcg cacgttcttt tgaacttcca atcatttctg taacaggtta
     1921 taaaactcac acacgctcta aaggttacaa cgctggaaca gtatcgaacg acaaaaatgt
     1981 ttacacattg ggatttgacc gtgatgtaga gttctttgtt gatacagcag atgtcgatga
     2041 aacaaatcaa gaactttcag cggctaacat ttcaaatact ttcatttcag aacatgcaac
     2101 accagaggtt gatgcttatc gcttttctaa aattgcaaca gcagcaatca ctggtaacca
     2161 tttcaaagca gaagatagca tcacaccaga aaatgtctat agcactttga aagctgctat
     2221 tttgccaatg cgtaaatttg gtgcatctaa ccttgttatg tacgtgtcta gcgaggtgat
     2281 ggatgcttta gaacgttcta aagactttac acgctcaatc gcaactacat ctccacaagg
     2341 tattgatacc cgtgtcactt ctcttgacgg tgtgcaactt atcgaagttt gggatgatgc
     2401 acgtttcaaa actaaatttg atttcactac aggttttgtt aaagctgagg acggtaaaga
     2461 tattaatttc ttgattgttg ctaaaacagc tgttattgcc aaagccaaat ttaactctat
     2521 ctatctcttt gcgccagggc aacacacaga aggtgacggc tacttgtatc aaaaccgtct
     2581 ataccacgac ttgtttgttt tgaaatcgca agaagatggt atttatgtct cacataaatc
     2641 agcgtaggag gtagcagatg aaaaagtatt tcaaagaaaa tcaagtctac actgttcaag
     2701 aaggtagcga gcttgaagta caacttatcg cagatggttt tgaagttcta gaacttaaac
     2761 aagaagttgt tgaagaagtt gaagaacaag aagagaaacc taagcgtacc aaaaaatcta
     2821 aaaatgaggg tgaataatgg ctaaatataa agctgctaaa aacatattct ttaaatcgct
     2881 caataaaagc gtgatggttg atgaaactat tgagcttgat aaagaatacg ctgaccatgt
     2941 taatgctgat ttagctaaag cttttccaga cgttgaaaag gtgctagtac cgcttgagga
     3001 agaacccgag tcagtacctg aagaagtatc
//
LOCUS       DATWEK010000082         2920 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.082, whole genome shotgun sequence.
ACCESSION   DATWEK010000082 DATWEK010000000
VERSION     DATWEK010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2920
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.082"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..703
                     /locus_tag="VCR92_001831"
     CDS             <1..703
                     /locus_tag="VCR92_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEP4268865.1"
                     /translation="FVTEQMLKDIERIKANDFDYYRYIYLGEPVGLGNNVYNMSTFHP
                     LDSLPANDRLIGISFALDGGHQQSATACGAFGITAKGNVILIDTYYYSPAGKVVKKAP
                     SQLSQDIHSFTRSVVDKYRVQVLQYTIDSAEGALRNQMYLDFAIRWHPVAKLKKVTMI
                     DSFQSLLAQGRFYYLDTEANKIFIEEHRMYRWDEKTIQSDNPNVIKEDDHTCDVSQYF
                     ALDNAKILGLRVGNS"
     gene            713..2263
                     /locus_tag="VCR92_001832"
     CDS             713..2263
                     /locus_tag="VCR92_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEP4268866.1"
                     /translation="MGLIQKVKDFFNRGRYNMQTSNLNSILDHPKIAVSQEEYSRIQH
                     NLTYYQSKFDDVEYINSEGDVKRRKFNHLPIARTASKKIASLVYNEQAEITSDNKTVD
                     EFISYTLDNDRFNKNFERYLESGLALGGLAMRPYVDGDRIRVAFVQAPVFLPLQSNTQ
                     DVSNAAILTKAIKSEGRKNVYYTLVEFHEWVTADGNEQGSTKDKSYYRITNELYKSDI
                     SDALGQRVNLSELYPDLEQVTMFKDLSRPLFTYLKTPGMNNKDINSPLGLSIFDNAKT
                     TIDFINRTYDEFMWEVKMGQRRVIIPEQLTKLTAQREDGSITFKRRFETDQNIYTQLG
                     GGDMDANSIKDITTPIRSNDYITAISEGLKLFEMQIGVSAGMFSFDGKSMKTATEVVS
                     ENSDTYQMRNSIAALVEQSIKELCVSICELGKATGLYKGEIPELEDISVNLDDGVFTD
                     RNAELAYWMQMVSAGFAPQRLGIQKTLNVSEEEAKDYLVEINGELPPENDADLALYGR
                     KQVEEDDE"
     gene            2256..>2920
                     /locus_tag="VCR92_001833"
     CDS             2256..>2920
                     /locus_tag="VCR92_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEP4268867.1"
                     /translation="MSKRPVLNDQQFSLKMQGVSDIYAQMQQELFDNMIKRLIVRGSA
                     DLQENPYIWQMQKLNDMHMLNEENLKIITERTGIAEDLLRDVIANEGLKVYKDTKQQL
                     AEDLGRRDGEYIANGVTDSLEAYTSQAISDLNLINTTLPRSIQKTYKSIVEKSVAEVV
                     ISSKSADKAIRDTIMKWQKKNFTGFVDKGGREWRADAYARAIIKTTTFRVYNEMRTAP
                     AKE"
BASE COUNT          976 a          547 c          643 g          754 t
ORIGIN      
        1 ttttgtcact gagcaaatgc taaaagacat cgaacgtatt aaagctaatg actttgatta
       61 ttacagatat atctacctgg gcgagccagt cggacttgga aacaacgtat acaacatgag
      121 cacgtttcat ccgttggata gtttgccagc taatgatagg ctgattggta tttcctttgc
      181 acttgacggt ggtcaccagc agtcagcaac agcttgcgga gcatttggaa ttacagcaaa
      241 aggcaatgtc attttgattg atacttacta ctattcacca gcggggaaag tagtcaagaa
      301 agcgcctagt caattatcac aagacataca cagttttact cgttcggttg tggataagta
      361 cagagtgcaa gtgctacagt acacaatcga tagtgctgag ggggcattgc gaaaccagat
      421 gtatttagac tttgctattc gctggcatcc agtagccaag cttaaaaaag tgacaatgat
      481 tgacagtttt cagtcattgc ttgctcaagg acgattttat tatttagaca cggaagccaa
      541 taagatattt atcgaagagc atcgcatgta tcgttgggat gagaagacaa tccagtcaga
      601 taatccaaac gtcatcaaag aagatgacca cacatgcgac gtatcacaat actttgcctt
      661 ggacaatgct aaaatccttg gtttacgtgt cggaaacagt taggaggaca ttatgggtct
      721 aatccagaaa gtaaaagatt tctttaatcg tgggaggtat aacatgcaga cttcaaattt
      781 aaacagtatt cttgatcatc caaaaattgc agttagtcaa gaggagtaca gtcgtattca
      841 acacaatcta acttactatc aatctaaatt tgatgacgtc gaatatatta acagcgaggg
      901 tgatgtgaaa cgtcgcaagt ttaatcattt gccgattgca cgaacagcat cgaaaaagat
      961 tgctagctta gtttacaacg aacaagcaga aatcacatca gacaacaaaa cagttgatga
     1021 gttcatcagc tacacgcttg acaatgaccg ctttaacaag aattttgagc gctatttgga
     1081 aagtggtttg gcgttgggtg gtcttgctat gcgtccatat gttgacggtg atagaattcg
     1141 tgtagcattc gttcaagcac cagtattctt accgttgcaa tcaaatacgc aagacgtgtc
     1201 gaatgctgct atcttgacta aagcaatcaa gtcagagggc agaaagaacg tgtattacac
     1261 gctcgtagag tttcatgaat gggtgacagc tgacggaaac gagcaaggaa gtacgaaaga
     1321 taaaagctat tatcgtatca ctaacgagct ttacaagtca gacatcagcg acgcattagg
     1381 tcaacgtgtg aacttgtctg aattatatcc agaccttgag caagtcacaa tgtttaaaga
     1441 cttatcacgt ccattgttta cgtatctcaa gactccagga atgaacaaca aagacataaa
     1501 cagtccgctt ggtctatcta tctttgataa tgctaaaacg acaattgact ttatcaacag
     1561 aacttacgat gagttcatgt gggaagtcaa aatgggtcaa cgtcgtgtca ttatccctga
     1621 acaattaact aagctaacag cacagagaga agatggttca atcactttta aacgacgctt
     1681 tgagacagac caaaacatct atacacagct aggcggtggc gatatggacg ctaacagcat
     1741 taaggacatt acaacaccta tccgctcaaa cgactacatt acagccattt cagaaggtct
     1801 gaaactattt gagatgcaga ttggcgtgtc tgctggcatg ttctcgtttg acggcaagag
     1861 tatgaagaca gctaccgaag tagttagcga gaatagcgac acataccaaa tgcgcaatag
     1921 tattgctgct cttgttgagc aatcgattaa agagttatgc gtatctattt gcgaactcgg
     1981 taaagctaca ggtctgtaca agggcgaaat accagagcta gaagacattt cagtcaatct
     2041 tgacgatggt gtctttacag accgaaacgc agagcttgct tattggatgc aaatggtatc
     2101 agcaggcttt gcaccacaac gtttaggcat ccaaaaaaca ttgaatgtgt ccgaagagga
     2161 agctaaagac tatctagttg aaatcaatgg ggaattacca ccagaaaatg atgcagactt
     2221 agcgctttat ggcaggaaac aagtagagga agacgatgag taagagacca gtcttaaatg
     2281 accagcaatt ctctttgaag atgcaaggag ttagcgatat ttacgctcag atgcagcaag
     2341 aactctttga taatatgatt aagcgtttaa tcgttcgtgg tagtgctgat ttacaagaaa
     2401 atccatatat ttggcaaatg caaaagttga atgatatgca catgctaaac gaagagaatc
     2461 ttaaaattat cacggagcgc acaggtatag cagaggactt gttacgtgac gttatagcta
     2521 acgaaggatt aaaggtttac aaagacacta aacagcaact tgcagaggat ttaggcagga
     2581 gagatggcga atatattgcc aacggcgtga cagatagcct tgaagcttac acatcgcaag
     2641 cgattagtga cttaaacctt atcaatacga ctttgcctag gtcaattcaa aaaacataca
     2701 aatcaattgt tgagaagtcc gtagccgaag tggttatcag ttcaaaatca gctgataaag
     2761 ctattcgtga cactatcatg aaatggcaaa agaagaattt tacaggtttt gtcgataaag
     2821 gcggcagaga gtggcgagca gatgcgtacg caagagctat tattaaaacg acaacgttta
     2881 gagtttacaa cgaaatgcgc acagcaccag ctaaggaaat
//
LOCUS       DATWEK010000083         2920 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.083, whole genome shotgun sequence.
ACCESSION   DATWEK010000083 DATWEK010000000
VERSION     DATWEK010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2920
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.083"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..703
                     /locus_tag="VCR92_001834"
     CDS             <1..703
                     /locus_tag="VCR92_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEP4268868.1"
                     /translation="FVTEQMLKDIERIKANDFDYYRYIYLGEPVGLGNNVYNMSTFHP
                     LDSLPANDRLIGISFALDGGHQQSATACGAFGITAKGNVILLDTYYYSPAGKVVKKAP
                     SQLSQDIHSFTRSVVDKYRVQVLQYTIDSAEGALRNQMYLDFAIRWHPVAKLKKVTMI
                     DSFQSLLAQGRFYYLDTEANKIFIEEHRMYRWDEKTIQSDNPNVIKEDDHTCDVSQYF
                     ALDNAKILGLRVGNS"
     gene            713..2263
                     /locus_tag="VCR92_001835"
     CDS             713..2263
                     /locus_tag="VCR92_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEP4268869.1"
                     /translation="MGLIQKVKDFFNRGRYNMQTSNLNSILDHPKIAVSQEEYSRIQH
                     NLTYYQSKFDDVEYINSEGDVKRRKFNHLPIARTASKKIASLVYNEQAEITSDNKSVD
                     EFISYTLDNDRFNKNFERYLESSLALGGLAMRPYVDGDRVRVAFVQAPVFLPLQSNTQ
                     DVSNAAILTKAIQSEGRKNVYYTLVEFHEWVTADGKEQGSTKDKSYYRITNELYKSDI
                     SDALGQRVNLSELYPDLEPVTMFKDLSRPLFTYLKTPGMNNKDINSPLGLSIFDNAKT
                     TIDFINRTYDEFMWEVKMGQRRVIIPEQLTKLTAQREDGSITFKRRFETDQNIYTQLG
                     GGDMDANSIKDITTPIRSNDYITAISEGLKLFEMQIGVSAGMFSFDGKSMKTATEVVS
                     ENSDTYQMRNSIAALVEQSIKELCVSICELGKATGLYKGEIPELEDISVNLDDGVFTD
                     RNAELAYWLQMVSAGFAPQRLGIQKTLNVSEEEAKDYLAEINGELPPENDADLALYGR
                     KQVEEDDE"
     gene            2256..>2920
                     /locus_tag="VCR92_001836"
     CDS             2256..>2920
                     /locus_tag="VCR92_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEP4268870.1"
                     /translation="MSKRPVLNDQQFSLKMQGVSDIYAQMQQELFDNMIKRLIVRGSA
                     DLQENPYIWQMHKLNDMHMLNKENLKIITERTGIAEDLLRDVIANEGLNVYKDTKQQL
                     AEDLGRRDGEYIANGVTDSLEAYTSQAISDLNLINTTLPRSIQKTYKSIVEKSVAEVV
                     ISSKSADKAIRDTIMKWQKKNFTGFVDKGGREWRADAYARAVIKTTTFRVYNEMRTAP
                     AKE"
BASE COUNT          961 a          550 c          650 g          759 t
ORIGIN      
        1 ttttgtcact gagcaaatgc taaaagacat cgaacgtatt aaagctaatg actttgatta
       61 ttacagatat atctacctgg gtgagccagt cggacttgga aacaacgtat acaacatgag
      121 cacgtttcat ccgttggata gtttgccagc taatgatagg ctgattggta tttcctttgc
      181 acttgacggt ggtcaccagc agtcagcaac agcttgcgga gcatttggaa ttacagcaaa
      241 aggcaatgtc attttgcttg atacttacta ctattcacca gcggggaaag tagtcaagaa
      301 agcgcctagt caattatcac aagacataca cagttttact cgttcggttg tggataagta
      361 cagagtgcaa gtgctacagt acacaatcga tagtgctgag ggggcattgc gaaaccagat
      421 gtatttagat tttgccattc gttggcatcc agtagccaag ctaaaaaaag tgacaatgat
      481 tgacagcttt cagtcgttgc ttgctcaggg acgtttttat tatttagaca cggaagccaa
      541 taagatattt atcgaagagc atcgtatgta tcgttgggat gagaagacaa tccagtcaga
      601 taatccaaac gttatcaaag aagatgacca cacatgcgac gtatcacaat actttgcctt
      661 ggacaatgct aaaatccttg gtttacgtgt cggaaacagt taggaggaca ttatgggtct
      721 aatccagaaa gtaaaagatt tctttaatcg tgggaggtat aacatgcaga cttcaaattt
      781 aaacagtatt cttgatcatc caaaaattgc agttagtcaa gaggagtaca gtcgtattca
      841 acacaatcta acttactatc aatctaaatt tgatgacgtc gaatatatta acagtgaggg
      901 tgatgtgaaa cgtcgcaagt ttaatcattt gccgattgca cgaacagcat cgaaaaagat
      961 tgctagctta gtttacaacg aacaagcaga aatcacatca gacaacaaat cagttgatga
     1021 gttcatcagc tacacgcttg acaatgaccg ctttaacaag aattttgagc gctatttgga
     1081 aagcagtttg gcgttgggtg gtcttgccat gcgtccgtat gttgacggtg atagagttcg
     1141 tgtagcattc gttcaagcgc ctgttttctt gccgttgcaa tcaaatacgc aagacgtgtc
     1201 gaatgctgct atcttgacta aagcaatcca gtcagagggc agaaagaacg tgtattacac
     1261 gctcgtagag tttcatgaat gggtgacagc tgacggaaaa gagcaaggaa gtacgaaaga
     1321 taaaagctat tatcgtatca ctaacgagct gtacaagtca gacatcagcg acgcattagg
     1381 tcaacgtgtg aacttgtctg aattgtatcc agaccttgag ccggtcacaa tgtttaaaga
     1441 cttatcacgt ccattgttta cgtatctcaa gactccagga atgaacaaca aagacatcaa
     1501 cagtccgctt ggtctatcta tctttgataa tgctaaaacg acaattgact ttatcaacag
     1561 aacttacgat gagttcatgt gggaagtcaa aatgggtcaa cgtcgtgtca ttatccctga
     1621 acaattaact aagctaacag cacagagaga agatggttca atcactttta aacgacgctt
     1681 tgagacagac caaaacatct atacacagct aggcggtggc gatatggacg ctaacagcat
     1741 caaggacatt acaacaccta tccgctcaaa cgactacatt acagccattt cagaaggtct
     1801 gaagttgttt gaaatgcaga ttggcgtgtc tgctggcatg ttctcgtttg acggcaagag
     1861 tatgaagaca gctaccgaag tagttagcga gaatagtgac acataccaaa tgcgcaatag
     1921 tattgctgct cttgttgagc aatcaatcaa agagttatgc gtatctattt gcgaactcgg
     1981 taaagctaca ggtctgtaca agggcgaaat accagagcta gaagacattt cagtcaatct
     2041 tgacgatggt gtctttacag accgaaacgc agagcttgct tattggctgc aaatggtatc
     2101 agcaggcttt gcaccacaac gtttaggcat tcagaaaaca ttgaatgtgt ccgaagagga
     2161 agctaaagac tatctagctg aaatcaatgg ggaattacca ccagaaaatg atgcagactt
     2221 agcgctttat ggcaggaaac aagtagagga agacgatgag taagagacca gtcttaaatg
     2281 accagcaatt ctctttgaag atgcaaggag ttagcgatat ttacgctcag atgcagcaag
     2341 aactctttga taatatgatt aagcgtttaa tcgttcgtgg tagtgctgat ttgcaagaaa
     2401 atccatacat ttggcaaatg cataagttga atgatatgca catgctaaac aaagaaaact
     2461 tgaaaattat caccgaacgt acaggcatag cagaggactt gttacgtgac gttatagcta
     2521 acgaaggatt aaatgtttac aaagacacta aacagcaact tgcagaggat ttaggcagga
     2581 gagatggtga atatattgcc aacggcgtga cagatagcct tgaagcttac acatcgcaag
     2641 cgattagtga cttaaacctt atcaatacga ctttgcctag gtcaattcaa aaaacataca
     2701 aatcaattgt tgagaagtcc gtagccgaag tggttatcag ttcaaaatca gctgataaag
     2761 ctattcgtga cactatcatg aaatggcaaa agaagaattt tacaggtttt gtcgataaag
     2821 gcggcagaga gtggcgagca gatgcgtacg caagagctgt tattaaaacg acaacgttta
     2881 gagtttacaa cgaaatgcgc acagcaccag ctaaggaaat
//
LOCUS       DATWEK010000084         2717 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.084, whole genome shotgun sequence.
ACCESSION   DATWEK010000084 DATWEK010000000
VERSION     DATWEK010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2717
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.084"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..1782)
                     /locus_tag="VCR92_001837"
     CDS             complement(<1..1782)
                     /locus_tag="VCR92_001837"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEP4268871.1"
                     /translation="MADGKVVIQIDMDGKSAQSEVKSLKSSLLGLGESVNSMGSTFKS
                     VLGANLISSAVISGVNALTGAVKGAFSSTIDEGAKLQQSIGGIETLFKDSAGTVKNYA
                     QQAFETAGVSANTYMENVTSFSASLISSLGGDTAAAAELANTAMVDMSDNANKMGTDM
                     EYITQTYQSLARGNYAMLDNLKLGYGGTKSEMERLMKDAEKLTGEHYTVGDFADTVKA
                     IHAVQESLGITGTTAREASTTLSGSFSSMKAAWTDFKGNLADGELDITPSLQGLARTT
                     STFLFGNFIPMVTNVLSKLPQAFSTLMDSMGEEIQKGLKQIAPNLDIDIVGAFKNIKA
                     AAQMAFNPLFIFNFKSALSNVGAALQSIWSTFNNVAGGGFSWTLTISNAISALMVTIK
                     NGAKIVKRFMDSFSETGAMQQIKFAIDSVITAYTTLTYAVGEASIWSTLGTVIGNVAK
                     VIAQVVQAIADFISRLDPSIVQGFTNVLVGGIAGLMAFSAGTNLVSKGMKGLEFIKSF
                     NPFKMFKKNAKDGADGATEAVGQSKSKIAQILQGLASVIKSVGTSIAVAAKGIGTGLA
                     NAFVGLGTALKMAGPANIIALGTAVGIA"
     gene            complement(1800..2384)
                     /locus_tag="VCR92_001838"
     CDS             complement(1800..2384)
                     /locus_tag="VCR92_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000459714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage Gp15 family protein"
                     /protein_id="HEP4268872.1"
                     /translation="MFDISKRMDDRLVLNGKEYQLFLSFDNVLKVFDMWSDDRFPVQI
                     KPQLALVKLTNSSDFKNMEFETALNIYSEVFDKHIKSVRAIDAVERYDLEGNVIPQKP
                     REDSDDGKPLYSIKYDGEFIFSSFMQAYNIDLIEEQGKLHWQKFNALLSGLPDGTKLI
                     EVMKIRAWKPQKGDSSKEKQRMRELQEEYALPEE"
     gene            complement(2384..>2717)
                     /locus_tag="VCR92_001839"
     CDS             complement(2384..>2717)
                     /locus_tag="VCR92_001839"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268873.1"
                     /translation="FNIGNVSLEFLPSDEQSKYIQEKGLEIQNKAKTLTDDSSESDFE
                     TAMKVKALLDELFETMFDAETPQKLYKAVGENTLSYLRVFYQISNAIREVNAERQNDE
                     YFKQFLSE"
BASE COUNT          765 a          622 c          466 g          864 t
ORIGIN      
        1 tgcaataccg actgctgtgc ctaatgcaat aatatttgct ggtccagcca ttttaagagc
       61 cgtacctaat ccaacaaaag catttgccaa gcctgtacca atcccttttg ctgcaacagc
      121 aatactagta cccaccgatt taatgaccga tgcaagacct tgtaagattt gagcaatctt
      181 agatttactt tgacctacag cttctgtcgc accatctgct ccgtccttag cgttcttctt
      241 gaacattttg aacggattaa atgacttgat aaattcaagt cccttcatgc cttttgaaac
      301 taagttagtc cctgctgaaa acgccatcaa accagcaata ccaccaacta gaacattggt
      361 aaatccttgg acaatgcttg ggtctaacct tgaaataaaa tcagcaatag cttgtacgac
      421 ttgtgcaatg actttagcaa cattaccgat gactgttccc aacgtcgacc aaatagaagc
      481 ttcaccaact gcataagtca atgtcgtgta cgccgtaata acactatcaa tcgcaaattt
      541 gatttgttgc atagcgccag tttctgaaaa gctatccatg aatcgcttaa caatcttagc
      601 tccattttta atcgttacca tcaatgctga aatagcatta ctgattgtta atgtccatga
      661 aaatccacca ccagccacat tattaaacgt cgaccaaatc gactgcaaag ctgctcctac
      721 attgctcaaa gcacttttga aattgaaaat aaacaaagga ttaaaagcca tttgagcagc
      781 tgctttaata ttcttgaacg ctcctacaat gtcaatatca aggtttggag caatctgttt
      841 caaacctttt tggatttctt ctcccatact atccataaga gtagaaaagg cttgcggtaa
      901 tttagataaa acgtttgtaa ccataggaat aaaattcccg aacaaaaatg ttgatgtcgt
      961 tcttgccaaa ccttgcaaag atggcgtaat atccaattca ccatcggcta agtttccttt
     1021 gaaatcagtc caagccgctt tcatggagct aaaagaaccg ctcaaagttg ttgatgcttc
     1081 tcttgctgtc gttcctgtaa tcccaaggct ttcttgaact gcgtggatgg ctttaaccgt
     1141 atccgcaaag tcaccgactg tgtagtgttc accagtcagt ttttcggcat ctttcatcaa
     1201 gcgttccatt tcggatttcg taccaccata cccaagcttg aggttatcaa gcatggcata
     1261 gttcccacgg gctaacgatt gataagtttg tgtgatgtat tccatgtctg tacccatttt
     1321 gttggcgtta tcagacatgt ctaccattgc cgtatttgct aattcagcag ctgccgctgt
     1381 gtcaccgccg agcgagctaa tcaaactagc agagaatgag gtgacgttct ccatgtacgt
     1441 gtttgcggat accccagctg tttcaaaagc ttgttgagca tagtttttaa ccgtacccgc
     1501 tgagtccttg aatagcgttt caataccacc gatagattgt tgtaatttag ctccctcgtc
     1561 gatagtagat gagaatgctc ctttaactgc accagttaaa gcgttgacac cagaaatcac
     1621 agcagaacta atcaagttag cgccaagaac ggacttaaac gtacttccca tgctattaac
     1681 gctctcaccc aatccaagca acgaactttt taaggattta acctcggatt gtgcgctttt
     1741 gccatccata tctatctgaa tgacaacttt tccatctgcc atgttttccc tcctttcgtc
     1801 tattcttcag gcaatgcgta ttcttcttgt aattcacgca ttctttgttt ttcttttgag
     1861 ctatcgcctt tctgtggctt ccaagctcgg attttcataa cttcaattag ctttgttcca
     1921 tctggtaaac cagacaataa agcattgaat ttctgccaat gcaattttcc ttgttcttca
     1981 atcaaatcaa tgttgtaagc ttgcataaac gatgaaaaaa tgaactcgcc gtcatatttg
     2041 attgaataca gaggttttcc gtcgtctgag tcttctcgtg gtttttgggg gataacattc
     2101 ccttctaagt catagcgctc aactgcatca atcgctctaa cgctcttaat atgcttgtca
     2161 aacacttctg aataaatatt caaagctgtt tcaaactcca tatttttaaa atcagagcta
     2221 ttagtgagct taaccagtgc taactgtggc ttaatctgta ctggaaatct gtcatctgac
     2281 cacatatcaa agactttcaa gacgttatcg aacgaaagaa aaagctggta ctcttttcca
     2341 ttgagcacca gcctatcatc cattcttttg gaaatgtcaa acatcactca gatagaaact
     2401 gtttgaaata ttcatcgttt tgacgttctg cgttgacttc tcgaattgca ttgctaattt
     2461 gataaaatac acgcaagtaa gacaatgtgt tctcaccaac tgctttatac agtttttgag
     2521 gtgtttcagc atcaaacatt gtttcaaaca attcatctaa cagcgctttg actttcattg
     2581 ctgtttcaaa gtcgctttct gatgagtcgt ctgtaagagt tttagctttg ttttgaattt
     2641 caagaccttt ctcttgaatg tatttacttt gttcatcgct tggcaagaac tcaagactga
     2701 catttccgat attgaac
//
LOCUS       DATWEK010000085         2633 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.085, whole genome shotgun sequence.
ACCESSION   DATWEK010000085 DATWEK010000000
VERSION     DATWEK010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2633
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.085"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..1704)
                     /locus_tag="VCR92_001840"
     CDS             complement(<1..1704)
                     /locus_tag="VCR92_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEP4268874.1"
                     /translation="MAEGKVTIQIDMDGRKAQSEVKSLKSTLLSLGDGANKIGSSFKS
                     LLAANVVGSALMSGIGALKGGLTSMYGELSSNTKAWKTFEGNLTQVWGASEETSKKIS
                     QVKSTLQDYATQTIYSASDMAQTYSQLAAVGIKNTDQLVMGFGGLAAAAENPTQAMKT
                     LSQQATQMAAKPKVQWQDFKLMLEQTPAGIAAVAKEMGMSTSEMVTAVQDGKIATEDF
                     FNAVAKVGNSDQFKKMATEFKTVDQAIDGAKETLSNKLMPAFEKLNQFGIKTVVALTD
                     ALDKINFDKLADNLGKALDGIDIEGIMAKAEQAMKMFFNPIFVMKFKSALDSVKGALS
                     SIAGAFNSVAGGGWSWLMTASNYVSALIVTVRTGAKAVKKFMDSFAETGAMQQIKWAI
                     DSVIAAYSYLVSEVGEASIWSTLGTVIGNVAKVIAQVVKAIADFVSRLDPSIVQGFTN
                     VLVGGIAGLMAFSAGTNLVSKGMKGLEFIKSFNPFKMFKKNAKDGADGATEAVGQSKS
                     KIAQILQGLASVIKSAGTSIAVAAKGIGTGLANAFVGLGTALKMAGPANIIALGTAVG
                     IA"
     gene            complement(1719..2300)
                     /locus_tag="VCR92_001841"
     CDS             complement(1719..2300)
                     /locus_tag="VCR92_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage Gp15 family protein"
                     /protein_id="HEP4268875.1"
                     /translation="MFDISKRMDDRLVLNGKEYQLFLSFDNVLKVFDMWSDDRFPVQI
                     KPQLALVKLTNSSDFKNMDFETALNIYSEVFDKHIKSVRAIDAVERYDLEGNVIPRKP
                     REDSDDGKPLYSIKYDGEFIFSSFMQAYHIDLIEEQGKLHWSKFNALLSGLPDGTKLI
                     EVMKIRAWKPQKGDSAKEKQRMRALQEEYALPD"
     gene            complement(2300..>2633)
                     /locus_tag="VCR92_001842"
     CDS             complement(2300..>2633)
                     /locus_tag="VCR92_001842"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268876.1"
                     /translation="FVVGDCTLEFMPSDEQSKEMQAKADELKQRANSIDGIANEDSWG
                     AVQEIKAVLDEFFKTMFDNETPEKLYKAVGQNTMTYLKVFLQISKAINEVNAERQNDE
                     YFKQFLSE"
BASE COUNT          713 a          627 c          437 g          856 t
ORIGIN      
        1 tgcaataccg actgctgtgc ctaatgcaat aatatttgct ggtccagcca ttttaagagc
       61 cgtacctaat ccaacaaaag catttgccaa gcctgtacca atcccttttg ctgcaacagc
      121 aatactagta cccgccgatt taatgaccga tgcaagacct tgtaagattt gagcaatctt
      181 agatttactt tgacctacag cttctgtcgc accatctgct ccgtccttag cgttcttctt
      241 gaacattttg aacggattaa atgacttgat aaattcaagt cccttcatgc cttttgaaac
      301 taagttagtc cctgctgaaa acgccatcaa accagcaata ccaccgacta atacatttgt
      361 aaaaccttgt acaatgcttg gatctaaacg agaaacaaag tcagctatcg ctttaaccac
      421 ttgagctata acttttgcaa cattgccaat tactgtccca agcgttgacc aaatagaagc
      481 ttcaccaacc tctgaaacaa gatagctata tgctgcaatc acgctatcaa tagcccattt
      541 aatctgttgc atcgctcctg tttctgcaaa actgtccata aatttcttga cggcttttgc
      601 tcctgttcta accgttacta tcagagctga tacgtaatta ctagctgtca tgagccatga
      661 ccagccacca ccagcaacac tattaaaagc accagctatt gaactcaacg cacctttaac
      721 actgtctaat gcgcttttga atttcatgac aaaaatgggg ttaaagaaca ttttcatagc
      781 ttgctcagct ttagccatta ttccctcaat gtcgatacca tcaagcgctt tgccaagatt
      841 atcagctaac ttgtcaaagt taattttgtc taaagcatct gtaagcgcta caactgtctt
      901 aatcccgaat tgattaagct tttcaaacgc tggcatcagc ttgttagata gtgtttcttt
      961 cgcaccatct atggcttggt caactgtttt aaactctgta gccattttct tgaattggtc
     1021 actattacca accttagcta ctgcgttaaa gaagtcttct gtcgcaattt ttccatcttg
     1081 aacggctgtt accatttcag atgtagacat acccatttct ttggcaactg ctgcgatacc
     1141 tgctggtgtt tgttcgagca tcaatttaaa atcttgccat tgtaccttag gcttagcagc
     1201 catttgcgta gcttgttgtg acaaggtctt catggcttgc gttgggtttt cggcggctgc
     1261 tgcaagccca ccaaacccca taacaagttg atcggtattt ttgataccaa ccgccgctaa
     1321 ctgactgtac gtttgcgcca tgtcagacgc actgtagatt gtctgtgtag cataatcttg
     1381 caaggtactt ttgacttgac taatcttctt actggtttct tctgacgctc cccaaacttg
     1441 cgtcaagtta ccttcaaacg tcttccaagc ttttgtatta gagctaagtt ctccatacat
     1501 gcttgtaaga ccgcctttaa gcgctccaat tccagacatc aaagcagaac caactacatt
     1561 agcggctaat agtgatttaa acgagctacc aatcttatta gcgccatcac ctagactaag
     1621 caaagtgctt ttgagtgatt tcacttctga ttgtgctttt ctaccatcca tatcaatttg
     1681 gatggtcact ttaccttctg ccatattccc ctcctttctt aatcaggcaa tgcgtactct
     1741 tcttgtaaag cacgcatgcg ctgtttttct tttgcgctgt cgcctttttg tggcttccaa
     1801 gctcggattt tcataacttc aattagcttt gttccatctg gtaaaccaga caataaagca
     1861 ttaaattttg accaatgcaa tttcccttgt tcttcaatca aatcaatgtg ataggcttgc
     1921 ataaacgatg aaaaaatgaa ctcgccgtca tatttgattg aatacagagg ttttccgtca
     1981 tctgagtctt ctcgtggttt tctggggata acattccctt ccaggtcata gcgctcaact
     2041 gcatcaatcg ctctaacgct cttaatatgc ttgtcaaaca cttctgaata aatattcaaa
     2101 gctgtttcaa agtccatatt tttaaaatca gagctattag tgagcttaac cagtgctaac
     2161 tgtggcttaa tctgtactgg aaatctgtca tctgaccaca tatcaaagac tttcaagacg
     2221 ttatcgaacg aaagaaaaag ctggtactct tttccattga gcaccagcct atcatccatt
     2281 cttttggaaa tgtcaaacat tactcagata gaaactgttt aaaatattca tcgttttgac
     2341 gttcagcatt aacttcgtta attgcttttg aaatttgcaa gaacaccttg agataggtca
     2401 ttgtattttg accaacagct ttatagagct tttcaggtgt ttcattgtca aacatcgttt
     2461 taaagaactc gtctaagaca gctttgattt cttgaactgc tccccaagag tcctcgttag
     2521 caattccgtc aatgctatta gcacgctgtt tcaactcatc agcttttgct tgcatttctt
     2581 tgctttgctc atcgcttggc atgaattcaa gcgtacaatc tcctactaca aat
//
LOCUS       DATWEK010000086         2615 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.086, whole genome shotgun sequence.
ACCESSION   DATWEK010000086 DATWEK010000000
VERSION     DATWEK010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2615
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.086"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..1688
                     /locus_tag="VCR92_001843"
     CDS             <1..1688
                     /locus_tag="VCR92_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4268877.1"
                     /translation="FNNFFVKKRSQELGVLAILGFSKKELTQLLTLENLVILVLSYLV
                     SLLLGPTLYFLAVLVITHLLELTLEVQWFITANEIIESLGILVVVFLINVITNGLIIS
                     KQSLIEFVNFSRKAEKKIKIRKVRAIIAITALLLSYILCLATVFSSTRNMLLSIGMVP
                     VSLLIIVLVVLGTVFTIRYGLAFIVSLLKGNKKRLYRPLSNIIYPKFNYRIATKNKLL
                     TVLGGLLTVTVSVAGMMVMLYAYSLNGIERLTPSAIEYNVKSENGQVNVTTILENDQV
                     SLVDVDLLRLNTNPEVTITESGQTIPYFDIINYSDYKELMKAQGRINSIEGSKSLPLL
                     INYYPTEISLGKTFNLGNAYDVTVKQVSTHNVFSFSTSVTTLVVSDKLYAKLSSCFPE
                     KEMTIRTFNGNSIRSSEAFYNQFSMVPDVISSYSKEYTVKTANIATYIFITFLSILFI
                     ICTGSILYFTSLIEIMENKEEYGYLSKLGYSKKMIHRIPRYETGILFLIPVFIGIVNG
                     GMLLIYYKYLFMDTLVAGNIIMLSLLLCLLFFLIIYGTFYVLTLRSVTSIIKN"
     gene            1728..>2615
                     /locus_tag="VCR92_001844"
     CDS             1728..>2615
                     /locus_tag="VCR92_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268878.1"
                     /translation="MIRIKNITKSKFFGTAIILLQQLIALLILVYNRENLSLLFSEKV
                     ALVMTLIDTAFIWLATILRQKQGDIFKRIISIISLTIWQYLVSVLTRGTPLFLSSGLQ
                     IILLYCYTVEITNLILYGHKQFKDKLDKGLLIIIFVSITSLFVNSILFNFLFLMVFTI
                     LHLYPLLVIVLYYRSFRQQISVVRRSLILFSLLLLVILGSELYGEMLDVNQAFNNLGW
                     YLFPLIMSVIYYFKTIHDKLSFVTQRWLGDYKARIELLFLLLILCWIVLMKVLVKDFL
                     LFFIVVDASTLFCLVVISCI"
BASE COUNT          837 a          364 c          437 g          977 t
ORIGIN      
        1 atttcaataa tttctttgta aaaaaacgta gtcaagagct tggagtctta gcaatactag
       61 ggttttcaaa aaaagaatta acacaattac tgactttaga aaatcttgtt attctagttt
      121 taagttactt ggtaagttta ctattgggac cgaccttata ttttttagcg gtactggtaa
      181 ttactcatct attggaatta acattggaag ttcagtggtt tattacagct aatgagatta
      241 tagagtcttt aggaatatta gtcgtagttt ttctgattaa tgtcatcaca aatggactta
      301 tcattagtaa acagtctttg attgaatttg ttaatttctc aagaaaggct gagaaaaaaa
      361 ttaagataag aaaagtcaga gctattattg ctatcactgc attgctattg tcatatattt
      421 tatgtttggc gacagtgttt tcatccacac gaaatatgct attaagcata gggatggtac
      481 cggtttctct attgataatt gtcttagttg ttttaggaac agtgttcacc atcagatatg
      541 gattggcttt tatagtttcg ttattaaaag gaaataaaaa aaggttatac cgtcctctgt
      601 ctaatatcat ctatcccaaa tttaactatc gtattgcaac aaaaaataaa ttattaacag
      661 tcttgggagg tcttttaaca gtaaccgttt cagttgctgg aatgatggta atgctctatg
      721 cttattctct taatgggata gagaggttga ctccatctgc catagaatat aatgttaaat
      781 cagaaaacgg tcaagtcaat gttacaacta ttttagagaa cgaccaagtg agcttggttg
      841 atgttgacct attgagattg aacactaacc cagaagtaac tatcacagaa tctgggcaaa
      901 caattcctta ttttgatata attaattaca gtgattataa agagttaatg aaagctcaag
      961 ggagaataaa ttctattgaa ggtagtaagt cactcccatt gttaataaat tattatccaa
     1021 cagaaattag ccttggaaaa acctttaact taggaaatgc atatgatgtt actgtaaaac
     1081 aagtatcaac gcataatgtt tttagttttt ctacaagtgt cacgaccttg gttgtttctg
     1141 ataaattata tgctaaactt agttcttgtt ttccagagaa agaaatgaca attaggactt
     1201 ttaatggaaa ttcgattagg tcaagtgaag cattttacaa tcagtttagt atggttcctg
     1261 atgttatcag tagttatagt aaggaataca cagtaaagac tgctaatatt gcgacttata
     1321 tctttataac tttcctatcc atactcttta ttatttgtac aggtagtatt ctgtacttta
     1381 caagcctcat cgaaatcatg gaaaataaag aagaatatgg ctatctaagt aagctaggtt
     1441 atagtaaaaa aatgattcat cggattcctc gatatgaaac aggtatactt ttccttattc
     1501 ctgtattcat tgggattgta aatggtggta tgttgcttat ttactataaa tatttattca
     1561 tggatacatt ggtagcaggc aatatcataa tgttatcttt attgctttgt ctgcttttct
     1621 tcttgataat atatggcaca ttttatgtat tgacattgcg gtcagtgaca tccataatca
     1681 aaaattaatt ttaaaaatct tttaacttta acgattaagt aaataatatg ataagaataa
     1741 aaaacataac aaagagtaag ttctttggga ctgcaataat cttgttgcaa caattaatag
     1801 ccttgttaat tttggtctat aatcgagaga acctgtctct tcttttctct gaaaaagtag
     1861 ctcttgtaat gacccttatt gatacagctt ttatttggct ggcaacaata ttacgccaaa
     1921 aacaaggtga tatttttaaa aggattattt ctatcatctc cttaacaatt tggcaatact
     1981 tagtatctgt gctgacaaga ggaactcctc tctttttaag cagtggacta cagattatat
     2041 tgctctattg ttataccgtt gagattacta atttaatatt atatgggcac aaacaattta
     2101 aagataagtt agataagggc ttgttaataa ttatttttgt ttctataact agcctttttg
     2161 ttaatagcat tttatttaat tttttattcc tgatggtttt tactatttta cacctgtatc
     2221 cgttactagt tatagtgcta tattataggt cctttaggca acaaatatca gttgttagac
     2281 gttcattgat actattttct ttacttttgc tggtaatact tggtagtgaa ctttatggag
     2341 aaatgctaga tgttaatcaa gcctttaata atttgggatg gtatctgttt ccccttataa
     2401 tgagtgtaat atactatttt aagaccatac atgataaatt gagttttgtt acccaaagat
     2461 ggttaggtga ttacaaagct cgtatagaac tattatttct acttcttatc ctttgttgga
     2521 ttgtactcat gaaggtatta gttaaagatt ttttgctatt ttttatagtt gttgacgcaa
     2581 gcacattgtt ttgtctagtg gtaatttctt gcatc
//
LOCUS       DATWEK010000087         2613 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.087, whole genome shotgun sequence.
ACCESSION   DATWEK010000087 DATWEK010000000
VERSION     DATWEK010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2613
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.087"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            21..635
                     /locus_tag="VCR92_001845"
     CDS             21..635
                     /locus_tag="VCR92_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HEP4268879.1"
                     /translation="MFKKENLKQRYFNFGLVALALTILAIIFAFSSKNADTKSYAKKS
                     ESKMVTIDKAPKNNHAITKEESKDKSKSIASEPIPTVENSVAPTVTEEAPVVQQEVTQ
                     TVQQVSSVAYNPNNVVLSNGNTAGIVGSQAAAQMAAATGVPQSTWEHIIARESNGNPN
                     AANASGASGLFQTMPGWGSTATVEDQVNAALKAYSAQGLSAWGY"
     gene            complement(1049..1921)
                     /gene="sdaAA"
                     /locus_tag="VCR92_001846"
     CDS             complement(1049..1921)
                     /gene="sdaAA"
                     /locus_tag="VCR92_001846"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEP4268880.1"
                     /translation="MFYTIEELVKQADQQFNGNIAELMIATEVEMSGRNREDIIKIMS
                     RNLQVMKAAVTEGLTSTKSISGLTGGDAVKMDNYIKKGNSLSDTTILNAVRNAIAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLATAIEKLDLSEKEQLEFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSAAAMSAAALVKAAGGTSHQASQAIAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGASFALVAADMALADIDSQIPVDEVIDAMYQVGSAMPTAFRETAEGGLAA
                     TPTGRRYSVEIFGE"
     gene            complement(1933..2604)
                     /gene="sdaAB"
                     /locus_tag="VCR92_001847"
     CDS             complement(1933..2604)
                     /gene="sdaAB"
                     /locus_tag="VCR92_001847"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEP4268881.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGDIPD
                     EVTFHLYNSFAKTYRGHGTDKALVAGIMGMDTDNPDIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKTLSVTGISIGGGNIQVTELNGFSVSLSMNTPTIVTVHKDI
                     PGMIAKVTDILSSNNINIATMNVTRESAGEKATMIIEVDSRECQEAANQIAKIPHIYN
                     VNFFD"
BASE COUNT          824 a          492 c          486 g          811 t
ORIGIN      
        1 gaaaagtgag gtattattga atgtttaaga aagaaaattt aaaacaacgt tattttaatt
       61 ttggattagt agcgttagct ctaacaatat tagccatcat ttttgccttc tcaagtaaaa
      121 atgctgatac taagtcttat gctaagaagt cagaaagtaa aatggtaaca atcgacaagg
      181 ctccaaaaaa taatcatgct attactaaag aagaaagcaa agataaatca aagagcattg
      241 cttcggagcc tattcccaca gtagaaaact ctgtagctcc gacagtaaca gaggaagcac
      301 cggttgttca gcaagaagtg actcaaactg ttcagcaggt atcttcagta gcctataatc
      361 caaacaatgt ggtactttcc aatggaaata ctgctggtat tgtaggaagt caagcggcgg
      421 cacagatggc agcagcaaca ggtgttccac aatcaacttg ggaacatata attgcgcgtg
      481 aatctaatgg aaatcctaac gcagctaatg cttctggggc atcagggttg ttccagacaa
      541 tgccaggttg gggttctaca gcaacggttg aagatcaagt caatgcagcc ttgaaagcct
      601 atagtgcaca aggtttatca gcttggggtt actaaataaa catagctgga agaaataaaa
      661 cctattgtta gtatttacta acaataggtt tttggtattt aattgtcttt atgatttgta
      721 gtgatgaatt agtctcaaaa caaaacattg ccttatcagg gaatatagct cgtattattt
      781 aggaaaactg accagcactt aagtgcctct gatatttaag gcagttatac tgataacaag
      841 caggaaaaaa actcttaaat gtttataaga tcattagcaa ttttcagtat tttacactac
      901 tacacttttg agttttaaca atttactaga agttgtttct aaggggaaac aacatagctt
      961 gatagctatc tattagtcat tttagtgaat atatagcaga aaaataaaac gctttcaaat
     1021 atttctaaga atttttctaa ctatctattt attcgccaaa tatttctacg ctgtaacgtc
     1081 gtccagttgg agtagcggct aaaccacctt ctgctgtttc acggaaagca gttggcatgg
     1141 cagagccgac ttgatacata gcatcaataa cttcgtcaac aggaatttga gaatcaatat
     1201 cagctaaagc catatcagct gcgacaaggg cgaaacttgc tcctagagca ttgcgtttga
     1261 cacaaggcac ttctactagg ccggcaacag gatcacagac aagtcctaat aaatttttga
     1321 taacaaacgc aatagcttga ctagcttgat gagatgttcc accagctgct ttaacaagag
     1381 cagctgcact catagcagct gcagaaccaa cttctgcttg gcatccacct tctgcaccag
     1441 aaatagaggc gttatttcca ataacaagac caaaagctcc tgcagtaaat aaaaactcta
     1501 attgttcttt ttctgataag tcaagttttt caatagctgt tgcgagcact gctggtaagc
     1561 atcctgcact tcctgcagtg ggtgttgcac agacaagtcc cattttagca tttaattcgt
     1621 ttacagctat agcatttcta acagcattaa gaatagtagt atcagaaagg ctgttccctt
     1681 ttttaatgta gttatccatt ttgaccgcat cgccccctgt caaaccactg atagatttgg
     1741 ttgaggttag tccttctgtt acagctgctt tcataacttg taaattgcgt gacatgattt
     1801 tgataatatc ttctcgattt cttccagaca tctccacttc cgtggcaatc atgagttcag
     1861 caatatttcc attaaattgt tggtcagctt gtttgacaag ttcttcaata gtataaaaca
     1921 tagctttcct ttctagtcaa agaagttgac attataaata tgaggaattt ttgcaatttg
     1981 gttggctgct tcttggcact ctctagaatc gacttctata atcatagtag ctttttcacc
     2041 agcggattca cgtgtaacat tcattgtggc gatattaata ttattggaag ataggatatc
     2101 agttaccttt gcgatcattc cgggaatatc tttgtgtaca gtaactatag taggggtatt
     2161 catggataac gagacagaaa aaccatttag ttctgttact tgaatgtttc ctcctccaat
     2221 tgaaatacca gtaacactaa gtgttttgtc agcttttttg acactgattt taacagtatt
     2281 gggatgggga gcattactat cttttaagat atcccaatag atttttatcc ctttttgatg
     2341 agcaatttct agagaatttt taatatcagg attatcagta tccataccca taattcctgc
     2401 aacaagagcc ttatcagtac catgtcctct gtaggtttta gcaaatgaat tataaaggtg
     2461 aaacgtcact tcatcaggaa tatctccaaa gatggaatgg actaccttac caattctgac
     2521 ggcaccagct gtgtgactac ttgatggacc aatcattact ggcccaatga tgtcaaaaac
     2581 tgattgaaat ttttgtgtat tcataggcaa ctc
//
LOCUS       DATWEK010000088         2608 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.088, whole genome shotgun sequence.
ACCESSION   DATWEK010000088 DATWEK010000000
VERSION     DATWEK010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2608
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.088"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            261..995
                     /locus_tag="VCR92_001848"
     CDS             261..995
                     /locus_tag="VCR92_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HEP4268882.1"
                     /translation="MNLSIFGLKNIPYLKEGDSIEKLIEESIKTSGFFIEDNDVLCIA
                     SKVVSIAEGQVMSLNEIQVSDVAKEIHRNIPRKDPRIIEIMLNLVNRDLSRLDIKKNY
                     IGCRLENGLKLTSGGIDRKSVDEVFLLPNNPDASAKRISEYLKKSLGKNVAVVITDSD
                     GREDKRGATQVAIGIYGIHPLRKTEVIDSQGETIKFQEETLCDMIAACAGLVMGQRGT
                     GIPAVLIKGLDYKWSENTSIKEALNE"
     gene            988..1974
                     /locus_tag="VCR92_001849"
     CDS             988..1974
                     /locus_tag="VCR92_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HEP4268883.1"
                     /translation="MSRNQDCKNILIIGFGKIGKIKAYKWLSRGYEVYVKDLKFSSMK
                     YLNTNSDVLDDLSRQYFTIEICTPTNHHLTLLKTVITRYVYSYISIEKPLCNRLEDLE
                     EMKSLVESHPHLAKKMFASEQYFFSKILEKLLQVDCFSLDKIKEITVNFSKDRIEDNE
                     NGRFLDKEILGYGIEIPHIIAVISYLGISLEEFKKGIFVNAIYIKDLEKHDYSIEILS
                     CINQTVIKIISNLGSFAIREGKIEGGDAKTVRRVTIDDKTILFDPHPKLERYKSELVT
                     GTNTFQIHDDMMDTYISLLEGNAIPEDCYINNAIEITKLLINLYSECEKIYL"
     gene            1984..>2608
                     /locus_tag="VCR92_001850"
     CDS             1984..>2608
                     /locus_tag="VCR92_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="HEP4268884.1"
                     /translation="MDLKITNGFYDPSHLSYEVVERKGLGHPDTLADGIAEQIEIDYS
                     LYCLDKFGVIPHHNFDKIIIRGGHSVQDFGGSDFIEPIKIIFLGRASKKCFNSSIPLF
                     KIQKKAATKYLNRILPNLDVENYVEFETLTSDFTTKTNWFSPEAIEDLPEYLDVPKAN
                     DTATMISYWPLTISEELALMIEGYFYKLDKNELPTPRFTKMGGDIKVM"
BASE COUNT          979 a          312 c          506 g          811 t
ORIGIN      
        1 ggtagacaag gttattccaa aattgaaaaa atatatttac tatattcact gtaagaacta
       61 tgttaacaat gatttaggaa tacattatgt agaactaggt aaaggaatta tcgattataa
      121 aacaatcatt catgaaatcc atgaacattt tatagactta atttttagtt tagaagtaca
      181 tgaaaaagaa atagacaaaa aggcagaagt agtgaggaag tcttatctga cactaaatga
      241 gtatattaat ggaggctaaa atgaatttga gtatatttgg tttaaagaat attccttatt
      301 tgaaagaagg ggatagtata gaaaagctta ttgaagaaag cattaaaact tcaggatttt
      361 ttatcgaaga caatgatgtg ctttgcatag cttctaaagt tgtatctatc gcagaaggcc
      421 aggtgatgtc tttaaacgag atacaagtga gtgatgtagc aaaagaaatc cacaggaata
      481 ttcctcgtaa agatcctaga ataattgaaa ttatgctaaa tttagtcaat agagatctgt
      541 cacgtttaga tatcaaaaaa aattacattg gttgtcgctt ggaaaatggt ttaaagttga
      601 caagtggtgg aatcgataga aaatcagtag atgaagtatt tcttttacct aataatccgg
      661 atgcttctgc aaaaagaatt tcggaatatc ttaaaaaatc acttggaaaa aatgttgcag
      721 ttgttataac agatagtgat ggtagagagg ataaaagagg tgctactcaa gtagcaattg
      781 gtatttatgg tattcatcct ttgagaaaaa cagaagtaat agattcacaa ggagagacaa
      841 taaaattcca agaagagact ttgtgtgata tgattgcagc ttgtgctggc ttagtaatgg
      901 ggcaacgtgg aactggaatt ccagctgtcc tcattaaggg cttggattat aaatggtctg
      961 aaaatactag tattaaggaa gcgttaaatg agtagaaatc aggactgtaa gaatattcta
     1021 atcattggtt ttggaaaaat tgggaaaatt aaagcgtaca agtggctatc acgcggatat
     1081 gaggtatatg tcaaagattt gaaattctcc agcatgaaat accttaatac aaatagtgat
     1141 gtgttggatg atttatcacg acaatatttt actattgaga tttgtactcc gacaaatcac
     1201 caccttacgc tattgaaaac cgttataaca aggtatgtct attcttatat tagcattgaa
     1261 aaaccactgt gtaacaggtt agaagattta gaagaaatga agtcgctagt agaaagtcac
     1321 ccacatctag caaaaaaaat gtttgccagt gaacaatact tcttttcgaa aattttggaa
     1381 aaactgttac aagtagattg tttctctcta gataaaatca aggaaataac agttaatttt
     1441 tctaaagata ggattgagga taacgagaat gggagatttt tagataaaga gatattgggc
     1501 tatggaatag agattcctca tatcattgct gtcatttctt atttaggaat ttcattagaa
     1561 gaattcaaaa aagggatctt tgtgaatgct atttatataa aagacttaga gaaacacgat
     1621 tattcaatag aaatattatc ttgtattaat caaacagtga ttaaaattat tagtaatttg
     1681 ggaagttttg caataagaga gggcaagatt gaaggaggtg atgctaaaac agtaagaaga
     1741 gttaccattg atgacaaaac aatactattt gatccacatc ctaaactcga gaggtataag
     1801 agtgaattgg tgactgggac aaatacgttt caaatacacg atgatatgat ggacacgtat
     1861 atcagtttgt tagaaggaaa tgctattcct gaagattgct atatcaataa tgcaattgag
     1921 ataacaaaat tattaattaa cttatattca gaatgtgaaa aaatttattt atgaggtgta
     1981 actatggatt taaaaattac aaacggcttt tatgacccaa gtcatttatc atacgaagta
     2041 gtagaacgta aaggattagg gcatcctgat accttagcag atggaattgc tgagcaaatt
     2101 gaaattgatt actcacttta ttgtttggac aagtttggtg ttattccaca tcataatttt
     2161 gataagatta ttatccgagg gggacattca gttcaggatt ttggtggaag tgactttatt
     2221 gaaccaatta aaattatttt tctaggtagg gcgagcaaaa aatgttttaa tagttcaatt
     2281 ccacttttta aaattcagaa aaaggctgca actaaatatt taaatagaat tttacctaat
     2341 ttagatgttg aaaattatgt agaatttgag acattgacct cagattttac tacaaaaact
     2401 aattggttct cgcctgaagc aatagaagat ttaccggagt atctagatgt accaaaggca
     2461 aatgatacag ctacaatgat aagttattgg ccattaacaa tttctgaaga attagcatta
     2521 atgattgaag ggtattttta taaattagat aagaatgaat taccaacgcc aagatttact
     2581 aaaatgggtg gtgatattaa agtaatgg
//
LOCUS       DATWEK010000089         2565 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.089, whole genome shotgun sequence.
ACCESSION   DATWEK010000089 DATWEK010000000
VERSION     DATWEK010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2565
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.089"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..137
                     /locus_tag="VCR92_001851"
     CDS             <1..137
                     /locus_tag="VCR92_001851"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEP4268885.1"
                     /translation="VGWAMGRRMQDKLVTEAFNQAYNREKPKEGVIVHTDQGSQYTGA
                     "
     gene            165..392
                     /locus_tag="VCR92_001852"
                     /pseudo
     CDS             165..392
                     /locus_tag="VCR92_001852"
                     /inference="COORDINATES: protein motif:HMM:NF025063.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            519..674
                     /locus_tag="VCR92_001853"
                     /pseudo
     CDS             519..674
                     /locus_tag="VCR92_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039767.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(721..1251)
                     /locus_tag="VCR92_001854"
     CDS             complement(721..1251)
                     /locus_tag="VCR92_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HEP4268886.1"
                     /translation="MSNFISPVYEIKSIPIEKISPNDYNPNSVAPPEMKLLYDSIKSD
                     GYTMPIVCYYDKEEDRYSIVDGFHRYRIMLDYSDIYERESGRLPVSVIDKSLDYRMAS
                     TIRHNRARGSHDVDLMSQIVKDLHECGRSDNWIAKHLGMDKDEILRLKQITGLASLFK
                     DHEFNQSWEPEELLNE"
     gene            complement(1244..>2565)
                     /locus_tag="VCR92_001855"
     CDS             complement(1244..>2565)
                     /locus_tag="VCR92_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HEP4268887.1"
                     /translation="NQNVYDALIERLHFLFNEFPIVYISFSGGKDSGLLLNILLDFRD
                     KYYPDREIGVFHQDFEAQYSLTTKYVQETFTSLEGRKKVSLYWVCLPMATRTALSSYE
                     MFWYPWDDKTEDIWVRPMPSQDYVINLENNSITTYRYKMNQEDLAKQFGRWYKQIHGN
                     QKTVCILGNRASESLHRYSGFINKKYGYQKECWITKQFKDVWTASPLYDWSVEDIWHA
                     YYKFSYSYNELYDLFYKAGLKPSQMRVASPFQDYAVDSLNLYRIIDQETWVKLLGRVQ
                     GVNFSNIYGRTKAMGYKSIALPKGHSWKSYTQFLLSTLPVRLRNNYVRKFNKSIDFWH
                     KTGGGLAEETINELIEKGYRIARNGISNYTSFKHSRVIFLDQIPDDTDDIVTTKDIPS
                     WKRMCFCILKNDHICRTMGFGLTREQQKIVAFLKEKYKTSLKELESE"
BASE COUNT          840 a          517 c          357 g          851 t
ORIGIN      
        1 ttgttggttg ggcaatgggc cgacgtatgc aagacaagtt ggtaacagaa gctttcaatc
       61 aagcttataa tagagaaaag cctaaagaag gggtaatcgt ccatacagat cagggttctc
      121 aatataccgg agcatgattt caggacctac ttagacagaa aaaatgtaag tccaggatga
      181 gtcgaaaagg taatccatac gataatgcac tcatggaatc cttttataaa acattaaaaa
      241 gagagcttgt caatgatgct catttcgcaa ctattgagca agctcagctt gagattttta
      301 aatatagtga gacttactat aaccctaaac gtctgcattc agctttaggg tatctctcac
      361 ctgtagaatt tgaaaaaata gttactcatt agcttaactt tatgtctatt ttttcttgac
      421 aagtccaggg tatgaagtcc ccttatacac atactttcaa aacagctctc aatcctctgt
      481 ccgctacaaa aatacgtcac cgctgccctc cagctgcctc attcaacgac aaacttgaag
      541 ccacaaacag actcatcaag ggcattaagt acaatgcctt tagatttcag aactttgaca
      601 actttaaaac caaaatcctc atcgctttga acatccaaaa agagagaacc aatctgattc
      661 tctctcgttg ttaatgataa gtcacccact acagttgaca atgagtctct tacttcctgt
      721 ttactcattt aatagctctt ctggttccca agattgatta aactcatggt ccttaaaaag
      781 agaagccaat cctgttattt gtttcagtct taaaatttca tctttatcca ttcctaaatg
      841 ttttgcaatc cagttatcac ttcgcccaca ctcatgaaga tcctttacaa tctgactcat
      901 caaatcaaca tcatgacttc ctctagctct attatgtcga atggtagaag ccattcgata
      961 gtctaatgac ttatcaataa cagaaacagg taatctccca ctttcccttt cataaatatc
     1021 tgaataatct agcattatac gatatctatg aaaaccatca acaatactat accgatcctc
     1081 ttccttatcg taatagcaaa caatcggcat agtataacca tcagatttta tactatcata
     1141 caataatttc atttcaggcg gagcaactga attcggatta taatcatttg gagaaatctt
     1201 ttcaattgga attgatttaa tctcatagac tggactaata aaattactca ctttctaact
     1261 cctttaaact cgtcttatat ttctctttta aaaaggctac tattttttgt tgctctcttg
     1321 tcaaaccaaa ccccatagtt cgacaaatat gatcgttttt taaaatacag aaacacattc
     1381 gtttccagct tggtatatcc tttgttgtta caatatcgtc tgtatcatca ggaatttgat
     1441 ctaaaaaaat aacccttgaa tgtttaaaag aggtataatt tgaaatacca tttctagcaa
     1501 tacgatatcc tttttcaatt agttcattaa ttgtttcctc cgcaagtcct ccgcctgttt
     1561 tatgccaaaa gtctattgat ttattaaatt ttctaacata attatttctt aacctcactg
     1621 gtagcgttga taaaagaaac tgagtgtacg acttccacga atgacccttt ggtaaagcaa
     1681 ttgatttata tcccattgct ttagtacgtc cataaatatt cgaaaagtta actccttgaa
     1741 cacgtcccaa aagctttacc caagtttctt gatctattat tctataaaga tttaggctat
     1801 caacagcata gtcttgaaaa ggagatgcaa ctctcatttg tgatggtttt aaacccgctt
     1861 tatagaatag atcataaagt tcgttataag aataagaaaa cttatagtaa gcatgccata
     1921 tgtcttccac tgaccaatca tataagggag atgctgtcca gacatctttg aattgtttgg
     1981 taatccagca ttccttttga taaccatact ttttattgat aaaaccacta tatctgtgta
     2041 aggattctga agcacggttt cctaatatac aaactgtttt ttgatttccg tgaatttgtt
     2101 tataccacct accaaattgt ttcgctaaat cctcctgatt cattttataa cgataagtag
     2161 taattgaatt attttccaaa ttaataacat aatcttgaga tggcattggt cttacccaga
     2221 tatcttctgt tttgtcatcc cacggatacc aaaacatttc ataactacta agtgcagttc
     2281 tagtagccat cggtaagcac acccaataca aagaaacttt ttttctacct tctaaagaag
     2341 tgaatgtttc ttgaacatat tttgttgtta aactgtactg tgcttcaaaa tcttgatgaa
     2401 acacacctat ttctctatcc ggataatatt tatctctaaa atccagtaaa atattaagaa
     2461 gtaacccact atcttttcca cctgagaagg aaatatagac aataggaaat tcattaaaca
     2521 aaaaatgtaa tctttctatc aatgcatcat aaacattttg attta
//
LOCUS       DATWEK010000090         2468 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.090, whole genome shotgun sequence.
ACCESSION   DATWEK010000090 DATWEK010000000
VERSION     DATWEK010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2468
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.090"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..644)
                     /locus_tag="VCR92_001856"
     CDS             complement(<1..644)
                     /locus_tag="VCR92_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEP4268888.1"
                     /translation="MSRDPTLLIDESNLTIGSDGRAYYTFTADGDTKSVKIANNKCIG
                     TTRFNQLMIERGGKPTNYVAPVVVEGTGNPTGLFKDLKEISLELTDTKNSKLWSKIKL
                     NNQGMIEEYYNGTIKSEIIKTAEGTQQRISSETDKKLALINETVSGIRREYQDADRQL
                     SASYQASIDGLKATMANDKIGLQAEIKASAQGLSQKYDDELRKLSAKITTTSSGT"
     gene            complement(655..984)
                     /locus_tag="VCR92_001857"
     CDS             complement(655..984)
                     /locus_tag="VCR92_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268889.1"
                     /translation="MRGHNLLKDLNNIIINNKTIDRIICNNTIVYQRSWDLLFDGLLT
                     SAGKKLDIYPFYKIVINNAFFVKTPTTKNNTIFLAGHKILALQDSHFCFFRALEKSFF
                     VKIYGKN"
     gene            complement(971..2185)
                     /locus_tag="VCR92_001858"
     CDS             complement(971..2185)
                     /locus_tag="VCR92_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268890.1"
                     /translation="MTSVETIPIKIVFDRKDASEWQSTNPVIDEGELVVELDTHKLKV
                     GDGKTSYNDLPYYEGPQGESITKVQLSENGDLSVWIGDKETKLGNIKGQKGDKGTSIT
                     DITKDGETLTIKLSDDTQKIFNIPNGQKGDRGKGVESARIDESGHLKLKIEEESELDL
                     GNVKGESGPKGDSITITNHKRVSDGTQVSFSDGTQIVVPKGDTGDVNGINLEDYVKKS
                     ELKNVGSADVKAINDFLGLSQKVFTSSYSYTDSLLKSYAKPSYSASWYVNESTVSTKN
                     GDKVLITIHNTTTQADNYLEVAVTYVGANYVTATSTGRLLTTPGEVKVVTKKQAEKDY
                     AAKKHKHEISDIAGLNERLSGYLRQADIQSQLNNIGKLKDTQTGQYLEVKVVDKGQVP
                     SNTSGMIVFERS"
     gene            complement(2182..>2468)
                     /locus_tag="VCR92_001859"
     CDS             complement(2182..>2468)
                     /locus_tag="VCR92_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HEP4268891.1"
                     /translation="KGVKLVLTPTKAKMDAQTFEVTKDKQSIEVYPLSYTGVLTGDWY
                     KSKSVEINASEAQELALEMAYKEIADAKGATIIGKQSDKPKIILDGRRDR"
BASE COUNT          616 a          531 c          439 g          882 t
ORIGIN      
        1 gtgccgcttg aggttgttgt gatcttagca gataacttgc gcaactcatc atcatacttt
       61 tgcgatagcc cttgtgctga ggctttaatc tcagcttgta aaccgatttt atcattggcc
      121 attgtggctt ttaagccgtc tatgctagct tgatagctag ctgatagctg tctatctgca
      181 tcttggtact cacgtctaat gcctgagact gtctcgttga taagcgcaag ttttttatcg
      241 gtctcgctac taatacgttg ctgcgtgccc tctgcggttt tgataatctc agattttatt
      301 gtaccgttgt aatactcttc aatcatccct tgattattaa gcttgatttt tgaccaaagt
      361 ttggagtttt tagtatctgt taactcgagg ctaatctctt tgaggtcttt aaatagtcca
      421 gtcggattac ctgtcccctc gacaaccacg ggcgccacgt agttagttgg tttaccccct
      481 cgctcaatca tgagctggtt aaagcgagtt gtaccgatac atttgttatt ggctatttta
      541 acgctttttg tgtcaccatc agccgtaaat gtataataag cacgtccatc tgagccgatt
      601 gttaaatttg actcgtctat taaaagtgtt gggtctctac tcaaatgtta cctcctaatt
      661 tttaccgtaa attttgacaa aaaaactttt ttctaatgct ctaaaaaaac aaaaatgact
      721 atcttgtaat gctagtattt tatgccctgc taaaaaaatc gtattgtttt ttgttgtggg
      781 ggttttaaca aaaaatgcat tattgattac gattttataa aaaggataaa tatccaattt
      841 tttcccagcg cttgtcagca aaccgtcaaa aagcagatcc cacgaacgct gatagacaat
      901 cgtattatta caaataatac gatcaatcgt tttgttatta ataatgatat tatttaaatc
      961 ttttaacaaa ttatgacctc tcaaacacga tcatgccact ggtattgcta ggcacctgtc
     1021 ctttatcaac cactttaacc tcaagatatt gtccggtttg cgtgtctttt agcttaccga
     1081 tattattaag ctgtgactgt atatcagctt gtctgagata gccagacaag cgctcattaa
     1141 gaccagctat gtcactaatc tcatgcttat gttttttagc agcataatct ttttccgctt
     1201 gcttttttgt cactactttg acttcaccag gagtagtcag taagcgacct gttgaggtag
     1261 cagtcacgta gttagcacca acataagtca ccgctacctc caaataattg tctgcttggg
     1321 tggtagtgtt atgtattgta atcaatactt tgtcaccatt tttggtagaa actgtagatt
     1381 cgttgacata ccaactcgcc gaatagctgg gttttgcata actttttagt aagctatctg
     1441 tataactata gctgcttgta aacacctttt gagatagccc taaaaagtca ttaatagctt
     1501 taacatctgc agaaccgacg tttttaagtt cagatttttt gacataatct tccagattga
     1561 tgccgttgac atcaccagta tccccttttg ggacaacaat ttgtgtcccg tcgctgaaag
     1621 atacctgcgt tccatctgaa acacgcttgt gatttgtgat agtaatacta tcacctttag
     1681 gtcctgactc acctttaacg tttccaagat ctaactctga ttcctcttca atttttaatt
     1741 ttaaatgacc ggattcgtca atcctagcgc tctctacgcc cttacctcta tccccttttt
     1801 ggccattggg gatattaaag attttttgag tgtcgtctga tagtttgata gtgagtgtct
     1861 caccatcttt ggtgatgtcg gttatacttg tccctttgtc ccctttttga cctttgatgt
     1921 tgccaagctt agtctctttg tcgccaatcc acacagacaa gtcaccattt tcggatagtt
     1981 gtacttttgt tatggattct ccttgcggac cttcatagta aggcaagtca ttgtagcttg
     2041 ttttaccatc tccgaccttt agcttatggg tgtctagctc gacgactagt tcaccttcgt
     2101 caatgacagg gttagttgac tgccattctg aagcgtcttt tcggtcaaag acaattttta
     2161 ttggtattgt ttcgactgat gtcatctgtc cctcctccca tctaaaataa tttttggttt
     2221 atcggactgt ttgccgataa tagttgcacc tttggcatct gcaatctctt tataagccat
     2281 ctcaagagct aattcctgcg cctctgaggc gtttatctcc acagacttag atttatacca
     2341 atcacctgtt aaaacgcctg tatagctcaa aggataaacc tctatagact gtttatcttt
     2401 agtgacctca aacgtctgtg catccatttt tgctttggtt ggtgtcagta ctaacttaac
     2461 tcccttgt
//
LOCUS       DATWEK010000091         2343 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.091, whole genome shotgun sequence.
ACCESSION   DATWEK010000091 DATWEK010000000
VERSION     DATWEK010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2343
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.091"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..183
                     /locus_tag="VCR92_001860"
     CDS             <1..183
                     /locus_tag="VCR92_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP4268892.1"
                     /translation="TDEEKKKIFDRFYRVDKARTRQTGGFGLGLALAQQIVMSLKGNI
                     TVKDNDPKGSIFEVKL"
     gene            complement(308..556)
                     /locus_tag="VCR92_001861"
     CDS             complement(308..556)
                     /locus_tag="VCR92_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEP4268893.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG"
     gene            complement(610..1530)
                     /locus_tag="VCR92_001862"
     CDS             complement(610..1530)
                     /locus_tag="VCR92_001862"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEP4268894.1"
                     /translation="MSNEFINFEKISRESWKTLHQKAKALLTQEELKSITSLNDNISI
                     NDVIDIYLPLINLIQVYKIAQENLSFSKSLFLKKDIQLRPFIIGISGSVAVGKSTTSR
                     LLQLLLSRTHPNSQVELVTTDGFLYPNQFLIEQGLLNRKGFPESYNMELLLDFLDSIK
                     NGQTAFAPVYSHDIYDIIPNQKQSFNNPDFLIVEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSSHIETWYIERFLSILKLAKRDPHNYYAQYAQLPRSEAIAFARNVWKTVNLENL
                     EKFIEPTRNRAELILHKSADHKIDEIYLKK"
     gene            1765..>2343
                     /locus_tag="VCR92_001863"
     CDS             1765..>2343
                     /locus_tag="VCR92_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEP4268895.1"
                     /translation="MKKYLKKIGKMMTKMYYDENPDSLHDIHEVKVELLNHPFTFLTD
                     SGVFSKKMVDFGSQVLLETLNFKENERVLDLGCGYGPLGISLAKVQRVDATLVDINNR
                     ALDLARKNATNNQVAVTIFQSNIYENISGHFEHIISNPPIRAGKRVVHSIIEKSIDFL
                     VVNGDLTIVIQKKQGAPSAKAKMATIFGNVEIL"
BASE COUNT          784 a          331 c          432 g          796 t
ORIGIN      
        1 acagatgaag aaaagaaaaa gatttttgat cgtttttatc gagttgacaa agctagaaca
       61 cggcaaacag gtggatttgg cttggggttg gctttagctc agcaaatcgt gatgtcttta
      121 aaaggaaata ttacagtaaa ggataatgat cctaaaggta gtatttttga agtcaaatta
      181 taagctaaaa agggcgacca ataaggtcag cccttttaaa gttattttta actgtcaacg
      241 ctttattgta ttttttgagt ttttaccgta taaaaaaact ccagctggag ttttcattgg
      301 atatttatta gccaagtttt gcagcaaggc gtgctttatc gcggcttgct ttgtttttgt
      361 gaatcaaacc ttttgattca gctttatcga tgcttgaaga agcagcgcgg aaaagctctt
      421 cagatgggtt agcttcaaat gctttgatag cagtacgcat agctgatttt tgtgctgagt
      481 ttttttcgtt tgctttaacg ttaagttcag cgcgtttaat agctgattta atatttgcca
      541 atgttttcac ctccaaatta atctaactac attattatat agaaaatata tgcgtttggc
      601 aaccctttat cactttttga ggtaaatttc atcaatttta tgatcagcac ttttatgtaa
      661 aattaattca gcacggttac gtgtaggttc aatgaatttt tcaagatttt ctaaattaac
      721 ggttttccaa acgttgcgcg caaatgctat agcctcagat cgaggtaatt gtgcatattg
      781 ggcataataa ttatgagggt cacgttttgc taattttaaa atgcttagaa accgttcaat
      841 gtaccaggtt tcgatgtgac tgctgtctgc atcaatataa atagaaaaat caaagtaatc
      901 actcatatat aaacgattgt tttgttgatt ttgaaaaaca ttaatacctt cgacgataag
      961 gaagtcaggg ttattaaatg attgtttttg atttgggata atatcgtaaa tatcatgaga
     1021 atagacgggt gcaaaagccg tttgaccatt tttgatggaa tctagaaaat ctaagagaag
     1081 ttccatgtta taagattctg gaaatccttt acgatttaac agtccttgtt caataagaaa
     1141 ctgattagga tataaaaaac catcagtcgt taccagttcg acttgactat tggggtgcgt
     1201 tcgtgataat aaaagttgta aaagacgact agttgttgat ttaccaacag ctactgaacc
     1261 agaaattcca ataataaaag gccttaattg aatgtctttt tttagaaaaa ggcttttaga
     1321 aaaagaaaga ttttcttgcg caattttgta aacctggatc agattaatta atggaaggta
     1381 gatatcaatg acatcgttaa tactgatgtt atcatttaag ctagtaatac ttttaagttc
     1441 ctcttgtgtg agaagagctt ttgctttttg atgtaatgtt ttccaagact ctctagaaat
     1501 tttttcaaag ttgataaatt catttgacat ggtagctcct aatcatttga cagtgcttac
     1561 attataccat tttagttaaa aaataaataa tttttcgtta gtatttacac gaaaattaat
     1621 acgattaact caaaaaagcc acacattcct agtacaatta tcctgctata ttctaacaaa
     1681 tagttaaagt tcggttttta tttgtaatat agataaaatt gttaaaaaac aagcgtcttg
     1741 taaaccattt caaagtatga tagaatgaaa aagtacctta aaaagatagg aaaaatgatg
     1801 acaaagatgt attatgatga aaatccagat agtctacacg atattcatga agtaaaagta
     1861 gagctgctta atcatccctt tacttttttg acggattcag gtgtcttttc aaagaaaatg
     1921 gttgatttcg gtagtcaagt attattagag acactaaatt tcaaggagaa cgaacgtgta
     1981 ctggacttag gttgcggcta tggtcctctt gggattagtc tagccaaggt tcaaagggta
     2041 gacgcaacct tagtggacat caataatcgt gctcttgatt tagctagaaa aaatgcaact
     2101 aataaccaag tggcagtaac tatttttcaa tcaaatattt atgaaaatat tagtggccat
     2161 tttgagcata ttattagtaa tcctcctatt agagcaggaa agagagtagt tcatagtatt
     2221 attgaaaaaa gcatagattt tttagtggtt aatggtgact taacgattgt gattcaaaaa
     2281 aaacaaggag ctcctagcgc taaagcaaaa atggcaacta tttttggtaa tgttgagata
     2341 tta
//
LOCUS       DATWEK010000092         2330 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.092, whole genome shotgun sequence.
ACCESSION   DATWEK010000092 DATWEK010000000
VERSION     DATWEK010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2330
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.092"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            1357..>2330
                     /locus_tag="VCR92_001864"
     CDS             1357..>2330
                     /locus_tag="VCR92_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001161118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEP4268896.1"
                     /translation="MGEKGDKGDTGERGPQGIQGLQGPKGDQGIQGPKGADGKTQYTH
                     IAYANNATGGGFSQTDQTKAYIGMYVDFNATDSTDPTKYKWSKWKGSDGAQGIPGKAG
                     ADGKTPYIHFAYADDNKGTNFSLTDKNQQYMGYYSDYTQADSSDYTKYKWVDRLANVK
                     VGNKNLILKSNDLANPHKQSGANTTVTSTDDYFVIKSTGYTANAWGGMSWNMSISEVK
                     AGEEFSILMPVYIDSSVNLDNGWNFNLKNHPSNSTAYNYSIPVTKKDQWFNVAITFKA
                     YKDVVFDTYPFYVYLVKNGLVRIKPPMLVRGNVIPSDYVVAPEDTQAD"
BASE COUNT          766 a          467 c          535 g          562 t
ORIGIN      
        1 gaaatcacgc tgactaatgt taatgatgga gtcaaaggac cgcaaggtga acaaggccca
       61 caaggaccaa aaggcgataa aggcgataaa ggcgaggacg gtatcgccgg taaagacggt
      121 gtaggcttga aatcaacagt cgtcacttac ggtttgagcg catctgaaac cacacgacca
      181 acaaactgga ctgaacaagt gccagctctg accaaaggca agtatttgtg gactaaaaca
      241 gtatggactt atacagataa cactaacgaa acaggctacc aaaaaacata tatcgccaga
      301 gatggtaaca acggtaatga tggcatcgct ggtaaggatg gcgtaggtat caagtcaacg
      361 actatcactt atgcaagctc aacttctggc ataactaagc ctacaagtgg ctggtctagc
      421 actattccga gtgtttcagc tggtaacttt ctttggacta agaccgtttg gacgtacacg
      481 gacaatactg gcgaaactgg ctattccgtt gcgaaaatgg gtgagactgg agccaaagga
      541 gacaaaggag acaaaggtga taagggcgac aagggagaca gaggttcaga cggaatcgct
      601 ggtaaagatg gtgtggggtt aaaatcaaca cttgttactt atggaatgag tgcatctgaa
      661 actacacaac caagtggctg gagtgctcaa gtaccaacac tgacaaaagg taattactta
      721 tggactaaga ctatttggac ttatacagat aataccactg aaacgggtta ccagaaaact
      781 tatattgcca aagatggtaa tgatggcgct gacggtatcg caggtaaaga cggtgtgggg
      841 ttggttaata ctacattacg atattgcaag tcaaacgatg gagtaaataa accaacagga
      901 agcgtaatcg catcatttcc tgacaaaatt acaccttctc gttcagtagt tgacaatctt
      961 gtaatgactg ggaaatatgt tcatcttgaa caaggaaaga cttatatctt gtcagctgaa
     1021 accaatgggg attttactaa ccagcacagc gataccgtaa gtagtaacaa tgctacaatt
     1081 tggattgtta atcctagttt tagtacttgg ctaattattt caaattctaa tacttcatta
     1141 ggtacgaaat acactcatac ccgtcctacc ggcgattatg aaatccgtgt taacagttac
     1201 acaccagaca atagcacttg ggttaagaat atagtatttg aagacggcac ttggtcgcct
     1261 gacattccag tagtaaatcc cggtgaattc ttatggactc ggacaacatg gttttattca
     1321 gacggcacca gtgagcaagg tttttctgtc gctaagatgg gcgaaaaagg tgacaagggg
     1381 gacactggtg agcgcggtcc gcaaggtatc caaggcttgc aaggacctaa aggtgaccaa
     1441 ggtatccaag gtcctaaagg agccgatggt aaaacacagt acacgcatat tgcctacgcc
     1501 aataatgcaa cgggcggtgg ctttagtcaa acagaccaaa ccaaagccta catcggtatg
     1561 tatgttgact ttaacgccac agacagtaca gacccaacca aatacaagtg gagcaagtgg
     1621 aaaggctctg acggtgcgca aggtattcct ggtaaagcag gagcagacgg gaaaacaccg
     1681 tacattcact ttgcttacgc cgacgataac aaaggtacta actttagctt gactgataag
     1741 aatcagcagt acatgggcta ctacagcgat tacacgcaag ctgacagtag cgattacaca
     1801 aaatataagt gggtggatag gctagcgaat gttaaagttg gcaacaaaaa cctcattcta
     1861 aaatcaaatg accttgcaaa tccgcataag caatctggtg ctaacacgac agtaacatca
     1921 actgatgact acttcgttat aaaaagcact ggctacacag cgaacgcatg gggcggtatg
     1981 tcgtggaata tgtctatttc agaagtgaaa gctggcgagg agttctctat tttgatgcca
     2041 gtttacattg atagttcagt caacttggac aacggctgga atttcaatct aaaaaatcat
     2101 ccttcaaatt caacggcata taactacagt atacctgtaa ctaaaaaaga ccagtggttt
     2161 aatgttgcaa tcacctttaa agcttataaa gatgtcgttt ttgatactta tccgttttat
     2221 gtttatctcg tcaaaaatgg tctagtacgc attaaaccgc ctatgcttgt tcgtggaaat
     2281 gtgataccaa gcgattatgt tgtcgcccca gaagataccc aagctgacat
//
LOCUS       DATWEK010000093         2296 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.093, whole genome shotgun sequence.
ACCESSION   DATWEK010000093 DATWEK010000000
VERSION     DATWEK010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2296
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.093"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..1224
                     /locus_tag="VCR92_001865"
     CDS             <1..1224
                     /locus_tag="VCR92_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEP4268897.1"
                     /translation="LNGLRAEFTRSNQGMRTELESKISGLRTVQQTTANQISQEIRDR
                     TGAVSRVQQDLESYQRRLQDAEDNYSSLTHTVRGLQSDVGSPTGKIQSRFTQLQYQID
                     QRVTRDGVMSIINQSGDSIKLAIQKAGGINAKMSGSEIISAINLNSYGVQIAGKQIAL
                     DGNTVVNGTFTTKIAEAIKIRADQIIAGTLDASKARIINLNASSIVGLDANFIKAKIG
                     YAIVDMLEGKVIKARNSAMLIDLSSAKMDFNSNATINFNSRDNALVRKDGTHTAFVHF
                     SNATPKGYTGSALYASIGITSSGDGVNSASSGRFAGLRSFRYATGYNHTAAVDQTELY
                     GDNVLIADDFSINRGFKFRPDKMEKVLDMNDLYAAVVALGRCWGHLANVGWNTAHSNF
                     TNAVTRELSNYIGII"
     gene            1236..1664
                     /locus_tag="VCR92_001866"
     CDS             1236..1664
                     /locus_tag="VCR92_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEP4268898.1"
                     /translation="MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVVDKIKE
                     YAKDEGDLIDLYAQKDKDGKFVIDERKNIKLADPTKIDELNDLLSELGNEDITIKGHE
                     YSKRFIDFLEYLAESEDEFTSDEIIIIDNILEEFEESKGE"
     gene            1667..>2296
                     /locus_tag="VCR92_001867"
     CDS             1667..>2296
                     /locus_tag="VCR92_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268899.1"
                     /translation="MKTLTLSGKPYPIHEGGKVVKTEVRLIGDNGLFIPIELIGDQTA
                     KGADDLIKEGLDAFVREYVTKYAVAESVQKVEELSLAQKEIEQNAEQAKVTAEAAEKQ
                     AKSLELVIAKSQKMANLQAIHLLTSGSKVEPDIYKGLLELIEPAKKGEYQAYDVFTVV
                     DESHEEQAGEGNLVFVHVNEPFTYDKQTLEELESEDKVTVIKYADLVKQD"
BASE COUNT          767 a          441 c          526 g          562 t
ORIGIN      
        1 ctcaatggct tacgtgctga gtttactcgc tcaaatcaag gtatgcggac agaactcgag
       61 tctaaaatca gcggactaag aacggtgcaa cagaccactg ctaaccaaat atcacaagag
      121 attagagaca ggacaggagc agtcagtcgt gtgcagcaag acctagagag ttatcagcgt
      181 cgtttgcagg atgcggaaga taattacagt agcttaaccc atacagttag aggtttgcag
      241 agtgatgtgg gatccccgac tggtaaaatc caatcacgct ttacgcagct gcaataccaa
      301 atagaccagc gagtgactcg tgacggagtt atgtcaatca ttaaccagtc tggagacagc
      361 attaaattag ctatccaaaa ggctggcggc attaatgcca agatgtctgg cagcgaaatc
      421 atctcagcga ttaacttaaa ctcctacggt gtgcaaatcg ctggtaagca gatagcttta
      481 gatggtaaca cggtagttaa cggcaccttt accacaaaaa tagccgaggc tatcaaaatc
      541 agagctgacc aaatcatagc aggcacttta gatgcctcta aagctcgtat tattaatcta
      601 aacgccagca gtatcgttgg tttagacgct aactttatca aagctaaaat tggctatgcg
      661 attgttgaca tgcttgaggg taaagtgatt aaggcacgca atagcgctat gcttattgat
      721 cttagctcgg ctaagatgga ttttaatagt aatgcgacca tcaactttaa cagccgagat
      781 aacgctttag tgcgtaaaga cggtacccac actgcctttg tacactttag taatgccaca
      841 ccaaaaggtt atacaggttc ggcattatat gcctctattg gtatcacctc atctggtgat
      901 ggggtcaaca gtgcgtcatc tggacgtttt gcagggctaa ggtcatttag gtatgctacg
      961 ggatataatc atactgctgc agtcgaccaa accgagctat acggtgataa tgtcttgatt
     1021 gcagatgact ttagcatcaa tcgaggattt aaatttagac cagacaaaat ggaaaaagtg
     1081 ctcgacatga acgacttgta tgcggctgta gtagccttag gccgctgttg ggggcacttg
     1141 gctaacgtcg gctggaatac tgctcatagc aattttacaa atgcggtcac tagagagttg
     1201 agtaattaca ttggtattat ttaaaaggag aaaacatgga tttaacgctt aaaaacaaag
     1261 atttaaacac attatatagt gtactagaca aaatcaaggt cacgaacatg cgagcaaacc
     1321 gcggacgtgc taagctactc gcaaaagtag tcgataaaat caaagagtac gccaaggatg
     1381 agggtgacct tattgatctg tatgctcaaa aagacaaaga tggcaagttt gtcatcgatg
     1441 agcgcaaaaa catcaagcta gcagacccga ctaagattga tgagctcaac gacttattgt
     1501 ccgaacttgg taatgaggac attactatca aaggccatga gtattctaag cgttttatcg
     1561 actttttgga gtacttggca gaatcggaag atgagtttac ctcagacgaa atcattatca
     1621 tcgataacat tttagaggaa tttgaagaaa gcaaaggaga ataactatga agacattaac
     1681 actatcaggc aaaccttatc caattcatga aggcggtaaa gttgtaaaaa cagaggttcg
     1741 cttaatcggt gacaatgggc tatttatccc cattgaatta atcggtgatc agacagctaa
     1801 gggagcagat gaccttatta aagagggact agatgctttt gtacgcgagt atgtgactaa
     1861 atacgccgta gcagaatcag tgcaaaaagt ggaagagttg agcctcgcac aaaaagagat
     1921 tgagcaaaat gcggagcaag caaaggtaac agcagaagcc gctgaaaaac aagctaaatc
     1981 tctggagctt gtcattgcaa aatctcaaaa aatggctaat ctacaagcaa tccatctact
     2041 aacaagcgga agcaaagtgg aacccgatat ttacaaaggt cttttagagc taatcgagcc
     2101 agccaaaaaa ggtgagtatc aagcctatga tgtctttacg gtagtagacg agtcgcacga
     2161 agagcaggca ggagaaggta atcttgtctt tgtacacgtt aacgagccat ttacttatga
     2221 caaacaaacc ttagaggagc tagagtcaga agacaaagta acagttatca aatatgcaga
     2281 cttagttaag caggat
//
LOCUS       DATWEK010000094         2290 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.094, whole genome shotgun sequence.
ACCESSION   DATWEK010000094 DATWEK010000000
VERSION     DATWEK010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2290
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.094"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..575
                     /locus_tag="VCR92_001868"
     CDS             <1..575
                     /locus_tag="VCR92_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEP4268900.1"
                     /translation="NPSESQFFSVITMQNHIPWSSDYPEEIVAEGKNFTEEENHNLTS
                     YARLLSFTDKETRAFLEKLTQINKPITVVFYGDHLPGLYPDSAFNKHIENKYLTDYFI
                     WSNGTNEKKNHPLINSSDFTAALFEHTDSKVSPYYALLTEVLNKASVDKSPDSPEVKA
                     IQNDLKNIQYDVTIGKGYLLKHKTFFKISR"
     gene            754..1449
                     /locus_tag="VCR92_001869"
     CDS             754..1449
                     /locus_tag="VCR92_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEP4268901.1"
                     /translation="MKKLIIIPAYNESSNIVNTIRTIESDAPDFDYIIIDDCSTDNTL
                     AICQKQGFNVISLPINLGIGGAVQTGYRYAQRCGYDVAVQVDGDGQHNPCYLEKMVEV
                     LVQSSVNMVIGSRFITKEGFQSSFARRIGIKYFTWLIALLTGKKITDATSGLRLIDRS
                     LIERFANHYPDDYPEPETVVDVLVSHFKVKEIPVVMNERQGGVSSISLTKSVYYMIKV
                     TLAILVVRLKGNR"
     gene            1451..1792
                     /locus_tag="VCR92_001870"
     CDS             1451..1792
                     /locus_tag="VCR92_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEP4268902.1"
                     /translation="MTVTASLFISFIVLTFVFFLINLIKKDKLAIKYSLLWFILALLI
                     LLFTWLPNILNKMSHFLGIHSPTNMLFFLGFCLSLAIIFSLTNNISLQNDKVKRLTQE
                     VALMKKEKTND"
     gene            1785..>2290
                     /locus_tag="VCR92_001871"
     CDS             1785..>2290
                     /locus_tag="VCR92_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEP4268903.1"
                     /translation="MINPSKQNQTIFLWNMLGSLSTAVISVILLMVVTRLLTSADSDI
                     YAFAYSFANMMVVVGLFQVRNYQATDINEKYSFSQYLVARLMTCLLMLAITVIYLTLT
                     KTDSYKSTIVFLVCFYRSTDAFSDLYQGMFQQHERLDIAGKSLAYRNTLIFMVYTAII
                     LYSKNLTLA"
BASE COUNT          762 a          342 c          398 g          788 t
ORIGIN      
        1 ttaatcctag tgaaagccaa tttttctcag ttattacaat gcaaaatcat attccttggt
       61 catccgatta tcctgaagaa attgttgctg aaggaaaaaa tttcacggaa gaagaaaatc
      121 acaacctaac aagttatgct cggttattat cgtttactga taaggaaaca agagcatttt
      181 tagaaaaatt aacacaaatt aacaagccta tcacagtggt gttttacgga gatcatttac
      241 ccggtttata tcctgatagt gcttttaaca agcatattga aaataaatac cttactgatt
      301 attttatttg gagtaatggt actaacgaga aaaaaaatca tccgcttatc aactcaagtg
      361 attttactgc agctttattt gagcatactg attcaaaagt atcaccttac tatgctttgt
      421 taacagaggt actgaataaa gctagtgtcg ataaatcacc agatagtcct gaagttaaag
      481 ctattcagaa tgatttaaaa aatatccaat acgatgtgac tataggaaaa ggttaccttt
      541 tgaaacacaa aacttttttt aagatatcac gttaagaaaa atgctaggct gtccgagtat
      601 agacgagcat caaggtttgg taatttgctc aaatgattgt caacagagtg tctaggacca
      661 ggtttaaaag attataattc ttaaggtctt attcgtttat aaaaaatgaa tactctttta
      721 aaatcttaat tgaaatgaat aggagaagtt ttcgtgaaaa agttaatcat tattcctgct
      781 tacaatgaaa gcagtaatat tgtcaatact atacgtacta ttgaatcaga tgccccggat
      841 tttgactata tcattattga tgattgctca acggataata cgttagcaat atgtcaaaaa
      901 caggggttca atgttatttc tttgcccatt aacctgggaa ttggcggtgc ggtgcaaact
      961 ggctatcgtt atgcacaaag atgtggatat gacgttgcag ttcaagtaga tggagatggt
     1021 cagcacaatc catgctattt ggaaaaaatg gttgaggtat tagttcaatc ttcagtaaat
     1081 atggtaattg gatcacgatt tatcacaaaa gaagggtttc agtcatcatt tgctcgacgt
     1141 atcggcataa agtattttac ttggcttatt gcgctactaa caggaaaaaa aataacagat
     1201 gcaacgtcag gtctaaggtt aattgaccgt tcattgattg aacgttttgc taatcattat
     1261 ccagatgatt atcctgaacc tgaaacagtt gttgatgtat tggttagtca ttttaaagtg
     1321 aaagaaattc ctgttgtaat gaatgagcga caaggcggtg tgtcatctat ctcgttgacg
     1381 aaatcggtct attatatgat taaagtgact ttagctattt tagttgttag attgaaagga
     1441 aatcgttaaa atgacggtaa cagccagttt atttataagt tttattgtat taacctttgt
     1501 tttctttttg attaacttaa tcaaaaaaga taaactagcg attaagtact ctttattgtg
     1561 gtttatttta gctttattaa ttttactatt tacgtggtta cctaacatat taaataaaat
     1621 gtctcacttc ctgggtattc attcaccaac caatatgtta ttctttttag gtttttgttt
     1681 gagtttagct attatttttt cactgactaa taatatttca cttcaaaatg ataaagtaaa
     1741 acgtctgacc caagaagtgg cccttatgaa aaaagagaaa accaatgatt aatccttcaa
     1801 aacaaaacca aacgattttt ttatggaata tgttaggaag tttatcaaca gctgtaatat
     1861 cagttatatt acttatggtg gttactaggt tactaacttc ggctgattca gatatttacg
     1921 cctttgccta ttcttttgct aatatgatgg tagttgttgg actttttcag gttcgtaatt
     1981 atcaagcaac agatattaat gaaaaatatt cctttagtca gtacttagtg gcaagactga
     2041 tgacttgttt attaatgtta gccataacag taatttattt aacgttaact aagacagata
     2101 gctacaagag tacaattgtc tttctagtct gtttctatag atcgacagat gctttttcgg
     2161 atttatatca gggaatgttc caacaacatg aacggctgga tattgcaggt aaatcgctag
     2221 cctacagaaa tactcttatt tttatggtgt acacagcaat aatattatat tccaaaaatc
     2281 ttactttagc
//
LOCUS       DATWEK010000095         2267 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.095, whole genome shotgun sequence.
ACCESSION   DATWEK010000095 DATWEK010000000
VERSION     DATWEK010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2267
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.095"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            43..333
                     /locus_tag="VCR92_001872"
     CDS             43..333
                     /locus_tag="VCR92_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEP4268904.1"
                     /translation="MKKLEQIRKESKEIKNKIDDTEERLRQLKNQEKKILKQDIEKRR
                     KERTHRLITRGAILESLIENAEELTDEEIKILLEEAIKTKEFKETLKLMREN"
     gene            801..1175
                     /locus_tag="VCR92_001873"
     CDS             801..1175
                     /locus_tag="VCR92_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005957761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268905.1"
                     /translation="MSCIMSQMNTGKIVFPSILAMMLLQSIVASIASLIFPAGLIGAK
                     VTEKLYTGKSYIVFLVFSSIIPAIYFTAIMSISGLLRMKGYDENFWKIYFSSFPINVV
                     FGYFSSIFWNVILDKFLRRKEA"
     gene            1177..1602
                     /locus_tag="VCR92_001874"
     CDS             1177..1602
                     /locus_tag="VCR92_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002840511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEP4268906.1"
                     /translation="MNKSIGKLITYLSRCIQQELKNVVVPFDISVGEEPYYMALTKQD
                     GLTQDELTKLVKVDKAATTRMVKSLEQKGYITRETDPKDKRNKKIYLTERGRLKYEPL
                     SRALKEFNQKLTSEWTDEQYKIVYQSLEMLQKKFEIDNK"
     gene            1877..1975
                     /locus_tag="VCR92_001875"
                     /pseudo
     CDS             1877..1975
                     /locus_tag="VCR92_001875"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            2098..>2267
                     /locus_tag="VCR92_001876"
     CDS             2098..>2267
                     /locus_tag="VCR92_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268907.1"
                     /translation="MAIKRIKLSIEEQIEKKEESIKQLKNQKIQLKKKLNEQERKARN
                     KRLIEKGAVFESV"
BASE COUNT          938 a          314 c          397 g          618 t
ORIGIN      
        1 aaaactctat cgtctttttt tattacaaga aaggagtttt gcatgaaaaa attagaacaa
       61 atcagaaaag aatcaaaaga aataaaaaat aaaattgacg atacagaaga aagattaagg
      121 caactaaaaa atcaagaaaa aaagatatta aaacaagaca tagaaaaaag aagaaaagaa
      181 agaacacata ggctcataac aagaggagca atcttagaaa gccttataga aaatgcagaa
      241 gaactaacag atgaagaaat aaaaatccta ctagaagaag caataaagac aaaagaattt
      301 aaagaaacac taaaactaat gagagaaaat taataaaaat aaagggtgtt gtaaataatc
      361 aaatctccct tagattttct aagggcgcaa ttatacagct atcagagatt gatgcattgc
      421 gttctccgaa ggctcctaat cggagggctg tgatttgtgc gatcaatgag ccaaacggat
      481 atacttgcat attcactcgc cgaatgcccc aacagccgac agaatgtcgg cttccgcagt
      541 catggtctgc tccaaatcaa acacggacgc tacgcttccc ctgcgctggc tgccgccagc
      601 caccctttga aaggaaaaat ttttataaac agtatttact acgaagttta ccaataaaat
      661 attattttaa gagatctaag cttaaaaaca aattagttga cgcatcaact aatttgtgat
      721 atacttaagt tattcttaaa agtgaggtaa gagtaatgaa atataaacgt tatattttcc
      781 ctatattgat ggggagtaca atgagttgta ttatgtctca gatgaatact ggaaaaattg
      841 tttttccgtc tatacttgca atgatgttat tacaatctat agttgcaagt atagcatctt
      901 tgatttttcc ggctggactt ataggtgcaa aagtaacaga gaaactatat actggaaaat
      961 catatattgt ttttttagtt ttttcatcaa taattccagc gatatatttt actgcaatta
     1021 tgtctataag cggattgtta agaatgaagg gatatgatga gaatttctgg aaaatatatt
     1081 tttcctcatt tcctattaat gttgtatttg gatatttttc tagtattttt tggaatgtga
     1141 tattggacaa atttttaaga agaaaagagg cataaagtga acaaaagcat tggaaaactt
     1201 ataacttatt tatcaagatg tattcagcaa gaattaaaaa atgtagttgt tccatttgat
     1261 ataagtgtcg gagaagagcc ttattacatg gcacttacaa aacaggatgg attgactcag
     1321 gatgaattaa caaaacttgt gaaagtagat aaggctgcta cgactcgaat ggttaaatca
     1381 ttagagcaaa agggatatat cacacgagaa acagacccta aagataagag aaacaaaaaa
     1441 atatatctta cagaaagggg acgattaaaa tatgaacctt taagtagagc attaaaagaa
     1501 tttaatcaga agttaacatc agaatggaca gatgaacaat ataaaatcgt ttatcaaagt
     1561 ctggaaatgc tacaaaaaaa atttgagatt gataataaat aagttttaat ttattgcccc
     1621 tctacacatc gggtcaactt gccacgaact ttcacaacta aatacccacc gctaaaacag
     1681 cggcacacca agcaggaaat ctgaaaaagg tctcctggta tggatacaat aaataataag
     1741 taatcatagg aggattttaa attagctaga cactacgaag aagacttcaa aaggcaaata
     1801 gtagaaatct ttaatcaagg taacaacaca tataaaaaat tgggagaaga atacgatata
     1861 gcaccgtcaa taatcagagt atgtttattg gaacaataac ctaagggtta atggatcatt
     1921 aggttacttg acaccagtta aatataggca atcaagatta actagtagtt attagttaat
     1981 ctaaaattag tacgttcgat tttagattgt acaaataggt gttgacaatc cacactaagc
     2041 tgaaaaacga ttagaaataa aaatctattc gtttttttat tttaagaaat gatacaaatg
     2101 gcaattaaaa gaataaagtt aagtattgaa gaacagatcg aaaagaaaga agaaagcatt
     2161 aagcaattaa aaaatcaaaa aatacagctg aagaaaaaac ttaatgagca agaaagaaaa
     2221 gcaagaaaca aaagacttat agaaaaaggt gcagtgtttg aaagtgt
//
LOCUS       DATWEK010000096         2267 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.096, whole genome shotgun sequence.
ACCESSION   DATWEK010000096 DATWEK010000000
VERSION     DATWEK010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2267
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.096"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..143
                     /locus_tag="VCR92_001877"
     CDS             <1..143
                     /locus_tag="VCR92_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEP4268908.1"
                     /translation="SKRTKKEKQLAERLKDDNFVKKYARAKYYLSREGEMIYPIPGLL
                     PK"
     gene            278..1564
                     /locus_tag="VCR92_001878"
     CDS             278..1564
                     /locus_tag="VCR92_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEP4268909.1"
                     /translation="MRKLLAAMLMTFFLTPLPVISTEKKLIFSKNAVYQLKQDVVQST
                     QFYNQLPSNPNLYQETCAYKDSDLTLPAGRLGVNQPLLIKSLVLNKESLPVFELADGT
                     YVEANRQLIYDDIVLNQVDIDSYFWTQKKLRLYSAPYVLGTQTIPSSFSFAQKVHATQ
                     MAQTNHGTYYLIDDKGWASQEDLVQFDNRMLKVQEMLLQKYNNPNYSIFVKQLNTQTS
                     AGINADKKMYAASISKLAPLYIVQKQLQKKKLAENKTLTYTKDVNHFYGDYDPLGSGK
                     ISKIADNKDYRVEDLLKAVAQQSDNVATNILGYYLCHQYDKAFRSEIKALSGIDWDME
                     QRLLTSRSAANMMEAIYHQKGQIISYLSNTEFDQQRITKNITVPVAHKIGDAYDYKHD
                     VAIVYGNTPFILSIFTNKSTYEDITAIADDVYGILK"
     gene            1561..>2267
                     /gene="tilS"
                     /locus_tag="VCR92_001879"
     CDS             1561..>2267
                     /gene="tilS"
                     /locus_tag="VCR92_001879"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEP4268910.1"
                     /translation="MMTYQEIFNEIKNKAYFKNHRHVLIAVSGGVDSMNLLHFLYLFQ
                     DKLKIRIGIAHVNHKQRSESDSEEAYLKCWAKKHDIPIYVSNFEGIFSEKAARDWRYA
                     FFKSIMLKNNYSALVTAHHSDDQAETILMRLIRGSRLRHLSGIKSVQPFANGQLIRPF
                     LTFSKKDLPEIFHFEDSSNRELSFLRNRVRNNYLPLLKQENPRFIQGLNQLALENSLL
                     FQAFKELTNHITTTDLT"
BASE COUNT          846 a          341 c          361 g          719 t
ORIGIN      
        1 tgtcaaagag gacaaaaaaa gaaaaacaat tagcagaacg actaaaagat gataattttg
       61 tcaaaaaata tgctagggca aaatactatt tatcgcgtga aggagaaatg atttatccta
      121 ttccaggact attaccaaaa tgatgatgga taatattgta aaaaaaatag aagcatttct
      181 tgctttttct gataaaaaat tagcagagct gcaacaggaa aatcaaaaag ttaaagaaga
      241 aagtcagtat attcaaaaaa actagaaagg agtcaatatg agaaaattat tagcggctat
      301 gttaatgact ttttttctga ctcctttacc agtgattagt acagaaaaaa aacttatatt
      361 ttcaaaaaat gctgtttatc aattgaaaca agatgtcgtt caatcaacac aattctataa
      421 tcagctaccc tctaatccaa atctttatca agaaacgtgt gcctataaag acagtgattt
      481 aactctacca gcaggaagat taggtgtaaa tcaaccatta cttattaaat cgcttgttct
      541 taacaaagaa tctttaccgg tttttgagtt agctgatggt acctatgttg aggctaatcg
      601 acaattgatt tatgacgata ttgtacttaa tcaagtagat atagatagct atttttggac
      661 acaaaagaaa cttaggcttt attcagcccc ttatgtttta ggtacgcaaa caattccttc
      721 ttctttttca tttgctcaaa aagttcatgc cactcaaatg gcacaaacaa accatggaac
      781 ttattatctt attgatgata agggctgggc atcacaagaa gatctagttc aatttgataa
      841 ccgcatgtta aaagtccagg aaatgctctt acaaaaatat aataacccaa attattcaat
      901 ttttgtaaag caactcaaca cacaaacaag tgctggtatt aatgctgata aaaaaatgta
      961 tgctgcaagt atctcgaagt tagcaccact ttatattgtt caaaaacaat tacaaaaaaa
     1021 gaaattagca gagaataaaa ctttgactta tactaaagat gttaatcatt tttatggaga
     1081 ctatgatcca ttgggaagtg gtaaaattag taaaatagct gataataaag attatcgtgt
     1141 tgaagaccta ctgaaagctg tagcacaaca atcggataat gtagcaacta atattttagg
     1201 ttattatcta tgtcatcagt atgataaagc tttccgctca gagataaaag ctttatcagg
     1261 tatcgattgg gatatggagc agcgcttatt aacttctcgt tcagctgcaa atatgatgga
     1321 agctatttat catcaaaaag gccaaattat ttcttacctt tcaaataccg aatttgatca
     1381 acaacgtatc acaaaaaata ttactgttcc agttgcacat aaaattggtg atgcttatga
     1441 ttataaacat gacgttgcta ttgtttacgg taatactcca tttattttgt ctatttttac
     1501 aaataaatca acctatgaag atattacggc tattgcagat gacgtttatg gtattttaaa
     1561 atgatgacct atcaagaaat ttttaatgaa ataaaaaata aagcctactt taaaaatcat
     1621 agacatgtgt taatagccgt atctggtgga gtagattcaa tgaatttatt gcacttttta
     1681 tacctgtttc aagacaaatt gaaaattcgt attggtattg ctcatgttaa tcacaaacaa
     1741 agatcagaat cagattcaga agaagcttat ttaaagtgtt gggctaaaaa acatgacata
     1801 cctatttatg tttctaattt tgaaggaata ttttcagaaa aagcagcacg tgattggcgc
     1861 tatgcttttt ttaaaagtat tatgttaaaa aataactatt cagctttagt aacagctcac
     1921 cattcagatg atcaagcaga aactattttg atgaggctaa ttagaggaag ccgattgagg
     1981 cacttgtcgg gtataaaaag cgtgcaacca tttgccaatg gtcaacttat aagacctttt
     2041 ttaactttct caaaaaagga cttgccagaa atttttcatt ttgaagattc ttcaaatagg
     2101 gaattatcat ttttaagaaa tagagttaga aataattatt taccattgtt aaagcaggaa
     2161 aatcctaggt tcattcaggg attaaatcaa ttagcacttg aaaatagctt actttttcaa
     2221 gcttttaagg agctaacaaa tcatattact accactgatt taacaga
//
LOCUS       DATWEK010000097         2195 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.097, whole genome shotgun sequence.
ACCESSION   DATWEK010000097 DATWEK010000000
VERSION     DATWEK010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2195
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.097"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            88..567
                     /gene="rlmH"
                     /locus_tag="VCR92_001880"
     CDS             88..567
                     /gene="rlmH"
                     /locus_tag="VCR92_001880"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEP4268911.1"
                     /translation="MKVKLICVGKLKERYLKDGISEYQKRLSRFCQFEMIELTDERTP
                     DKASFADNQLIMSKEAQRIHKKIGERDFVIALAIEGKQFPSETFSELISGVTVKGYST
                     ITFIIGGSLGLDSIIKKRANMLMSFGLLTLPHQLMRLVLTEQIYRAFMITQGSPYHK"
     gene            complement(725..798)
                     /locus_tag="VCR92_001881"
     tRNA            complement(725..798)
                     /locus_tag="VCR92_001881"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(762..764),aa:Arg,seq:tct)
     gene            963..1737
                     /locus_tag="VCR92_001882"
                     /pseudo
     CDS             963..1737
                     /locus_tag="VCR92_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001871253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            1932..2003
                     /locus_tag="VCR92_001883"
     tRNA            1932..2003
                     /locus_tag="VCR92_001883"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1965..1967,aa:Glu,seq:ttc)
     gene            2037..2110
                     /locus_tag="VCR92_001884"
     tRNA            2037..2110
                     /locus_tag="VCR92_001884"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2071..2073,aa:Asn,seq:gtt)
BASE COUNT          745 a          382 c          408 g          660 t
ORIGIN      
        1 tgtacaaagg tttttattag tagttgaaga aaaataactt gtggataaat tgtgtaaaaa
       61 gtaatgttct tgtgatacaa ttaagctatg aaagtgaaac taatttgtgt tggaaaacta
      121 aaagaaagat accttaaaga tggtatttca gaatatcaaa aaagactttc ccgtttttgt
      181 caattcgaaa tgattgagtt aactgatgaa agaacaccag ataaagcaag ttttgctgat
      241 aatcaattga ttatgagtaa agaagctcag cgaatccata aaaaaattgg ggaacgtgat
      301 tttgtaattg cattagctat tgaaggaaaa cagtttcctt cagagacatt tagtgaatta
      361 atatcagggg ttactgttaa gggatattca actatcacgt ttattattgg tgggagtctt
      421 ggattagatt caattattaa aaaaagagct aatatgctaa tgagttttgg attgttaacc
      481 ttacctcatc agttaatgcg tctagttctt actgagcaaa tttatcgtgc ttttatgatt
      541 acacaaggca gtccttatca taagtaagag agtgtgaact ggaataacta actcttacca
      601 ctttattaga taatagttcg gtataattaa aagcaaatat taaaaaaaga cgtactaaat
      661 cctatctttt caatacacta aggtaaatac aaaaaaaagc actaaaacag tgctttttta
      721 tctttgatcc cagcaggatt cgaacctgcg accgttcgct tagaaggcga atgctctatc
      781 cagctgagct atgagacctt aaccacatca ttttaacaaa aattatctaa aactgtcaat
      841 atttattttg aaaaaactag aaaataacat aatatcccgc gttgtaaaat gaagtgcaac
      901 aaaaaagaca tgttcatctg atatactaga attccccaat tcagtatgga aagcagatga
      961 acatgtctaa tattaattct accagaaagt catcctattc tcatctttca gccacagaac
     1021 ggggtgaaat tgctgcttat cttaaaatgg gaaagaaacc cgttgagatt gctcgacttc
     1081 tggggcgtca ctgttctaca atctgccgag aaataaaacg tggttcagta gatcaggtaa
     1141 aggataagaa tggaaaacaa accttcttca acgcctattt cgctgatagt gggcaacgtg
     1201 tctattaaac caatcgattt gcctaaggtg gttagtatca gaaaacgttc taagaaagtc
     1261 atgaagacga ataagaagac tttaggtaaa tctatcgaag aacgtccaga atatattaat
     1321 gatcgttctg aatttgggca ttgggagatt gatttggttc tcggcaagaa aaccaaaagt
     1381 gaagctgtta tgttgacttt ggtagagcgc cagacacgct atgcactagg agttaagcta
     1441 gaagacaagc agtcccaaac cattaaccgt gctgtcacgc atctcatcag tcagtatcct
     1501 attgcatcca tcacagcgga taatggttct gagtttagtt tactctcaga cttaaaagct
     1561 gttgacgttt actttgcaca tccctattct tcacatgaga gaggaacaag cgagaacttc
     1621 aatggcctcc tcagagaata tgtccctaaa ggagtctcac ttaatccact aacctctgaa
     1681 gaacttgaca atgatattac tgccatcaat gagcgcctaa gacgacttct tcaatagcaa
     1741 tcctcaaaat tcctgtttga gctatcccga acagcttaac ctctggaact ctagttatct
     1801 atgaactcgt tgcacttgac ttgacaactt gcggtttaaa aaaaatcaaa tttttttaaa
     1861 aaaagtatag acaaaaaaaa tcaatctgct ataatagtaa gagtgttaag gagatatcct
     1921 ccaaaacttc tggtccgttg gtcaaggggt taagacaccg ccttttcacg gcggtaacac
     1981 gggttcgaat cccgtacgga ctatcgcaat tgtcattttg gcaatttttt tctttttccg
     2041 gcatagctca gttggtagta gcgcatgact gttaatcatg atgtcgtagg ttcgagtcct
     2101 actggcggag tgataagata tttcctaaga taatcttagg atttttttat ttagtaaaac
     2161 agatactcag gtcaaatact caatttacta attat
//
LOCUS       DATWEK010000098         2194 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.098, whole genome shotgun sequence.
ACCESSION   DATWEK010000098 DATWEK010000000
VERSION     DATWEK010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2194
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.098"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            152..2143
                     /gene="uvrB"
                     /locus_tag="VCR92_001885"
     CDS             152..2143
                     /gene="uvrB"
                     /locus_tag="VCR92_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEP4268912.1"
                     /translation="MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPDNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFR
                     VEFFGDEIDRICEIESLTGKTIGEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQL
                     QLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDGRSPGEPPYTLLDFF
                     PEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIIYVSATPGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARD
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADKMTDSMQ
                     RAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRG
                     ERKEAINALQKQMQEAAELLDFELAAQMRDLILELKLMD"
BASE COUNT          738 a          363 c          471 g          622 t
ORIGIN      
        1 acaaaatgtt gaacattaag caagaaattt gttatttata tgtcataaaa cataacatgt
       61 aaatgacatg ttttttacgc ttattggagg tgattctggc ttatctatgt taaaatagtc
      121 tataagagat aagactatta gagggtataa aatgattgat aaacgtgatg ataaaccatt
      181 taaactaaaa tcaaagtata aaccgtctgg tgatcagcca caagctattg aaagcctagt
      241 tgataatatt gagggcggag aaaaagctca gattctccta ggtgctacag gaacgggaaa
      301 aacatacacc atgagccaag taattagtaa agtaaataaa cctaccttag tgatagctca
      361 caataaaacc ttagcaggac aattatatgg tgaatttaaa gaattttttc cagacaatgc
      421 tgtggaatac tttgtttcct attatgatta ctaccaacct gaagcatatg tcccatcaag
      481 cgacacctat atcgaaaaag atagttcagt caatgatgaa atcgataaac ttcgccattc
      541 agccacctct tctttacttg agcgtaacga tgtcatagtg gtagcttctg tatcttgtat
      601 ttatggacta ggttcgccaa aagagtacgc agattcagca gtcagcctac gtccaggtca
      661 ggagatatca cgtgacactt tgctaaatca attagtagat attcaatttg agcgtaatga
      721 tattgatttt caacgcggct gttttcgtgt acgtggcgat gttgttgagg tctttccagc
      781 atccagggat gaacatgctt ttcgggtgga atttttcggg gatgagattg atcgtatatg
      841 tgaaatcgaa agtttaactg ggaaaactat tggagaagtt gaccatttgg ttttatttcc
      901 agctactcac tttgtaacaa atgatgagca tatggagcaa tcaatagcca aaattcaagc
      961 agagttagca gagcagttac agttatttga atctgaaggt aaactactag aagcacagcg
     1021 attacgccaa agaacggaat atgatattga aatgttacgt gaaatgggct atactagcgg
     1081 agtcgaaaac tattcccgtc atatggatgg caggtcacca ggagaacctc cttatacctt
     1141 gttagatttc ttcccagaag attttttaat tatgattgat gaaagtcaca tgacaatggg
     1201 acaaatcaaa ggcatgtata atggtgacca agccagaaaa caaatgctag ttgactatgg
     1261 ttttcgattg ccatcagctc ttgataatcg tcccttaaga cgcgaggaat ttgaaagtca
     1321 tgtgcaccaa attatctatg tttcagcaac gcctggtgaa tacgaaatgt cacagactaa
     1381 tacaattatt gagcaaatta ttcgtccgac tgggctactt gatcctgaaa ttgatgtaag
     1441 gccaagtatg gggcaaatgg atgatttgtt gggagaaatt aaccagcgcg tagcgcgcga
     1501 tgaacggacg ttcatcacaa ccttaactaa aaaaatggca gaagatttga ctgattatct
     1561 aaaagagatg ggtgtcaagg tcaagtatat gcacagtgat attaaaacct tagagcggac
     1621 agaaattatt cgtgatttac gacttggtgt ttttgatgtc ttgattggaa tcaatctgct
     1681 ccgtgaaggg attgatgtgc cagaagttag tcttgtagcc attttggatg ctgataaaga
     1741 gggtttcctc cgtaatgaac gcggcttgat tcagaccatc ggtagagcag ctcgaaacgt
     1801 agatggtcat gtcattatgt atgcggacaa gatgacagat tctatgcagc gggctattga
     1861 cgaaacggct cgtcgtcgtg agattcaaat agcatataac aaagcgcacg gcatcgttcc
     1921 acaaactata aaaaaagaca tcagaggcct tattagtata agtaaaacaa gccacaatga
     1981 tatatcgaaa gaagagatgg attatgaaag tatgtcaaga ggagaacgaa aagaagcgat
     2041 caatgctctg caaaaacaaa tgcaagaggc agctgaatta cttgatttcg aattggcagc
     2101 tcaaatgcga gacttgattt tagaacttaa attaatggac taggttttga ataaagctta
     2161 tattatactt attaacatat ataagttaaa gtca
//
LOCUS       DATWEK010000099         2023 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.099, whole genome shotgun sequence.
ACCESSION   DATWEK010000099 DATWEK010000000
VERSION     DATWEK010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2023
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.099"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..1230
                     /locus_tag="VCR92_001886"
     CDS             <1..1230
                     /locus_tag="VCR92_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEP4268913.1"
                     /translation="LDGLRAEFTHSNQGMRVELESKISGLQSTQQATARQISQEISNR
                     EGAVSRVQQGLDSYQRRLQNAEGSYSSLQQTVSGLQSDVNSPNSKLNSRISQLASQID
                     QRVTRADVTSIINQSGDSIKLAIQRAGGIDAKMSAKEIVSAINLNGYGVRISGERIAL
                     DGNTTVNGAFGAKIGEFIKLKADQIIGGTIDANKINVINLNASSIVGLDANFIKARIE
                     YAITSLLEGKVIKARNGAMTIDLQSGQINHYTNESAMRRIDSSTASQFIKMTKSGFIS
                     EIGNMQAAMTVIGSNSDGSENHENKTFGGIRIWNGKSSYQSTSFVELVGNRVAIYGNK
                     NRSPWLFDSTTSGYAYLIPQNESGIKHAIGRADRKIDQIHVGDIYVQGERVAMMLKDL
                     ANRIGYIGTGGWANRIG"
     gene            1244..1405
                     /locus_tag="VCR92_001887"
     CDS             1244..1405
                     /locus_tag="VCR92_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268914.1"
                     /translation="MQEKLLGKIINDLTLKVANLTLENAQLKAQHEIELEELNAQLDE
                     ATAPKEEGK"
     gene            1408..>2023
                     /locus_tag="VCR92_001888"
     CDS             1408..>2023
                     /locus_tag="VCR92_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268915.1"
                     /translation="MRNWKVTGNYPQWDGTGAVIDTQVIITDDRGAVIAEKIKKDLRT
                     ANDAEIIEAALEEFKKTAYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQKMINLQTIHMLTSGGKIDPDIYKGMLELIEPAKKGEYQAYDVFTVVDSTKEED
                     GEAGEGNLVFVHVNEPFTYEAQTLKDLESEDKVTVIKYADLVKQD"
BASE COUNT          701 a          357 c          488 g          477 t
ORIGIN      
        1 ctcgatggct tacgagctga gtttactcat agtaatcaag gtatgcgcgt agagctggag
       61 tcaaaaatca gtgggttgca atcaacgcaa caagcaactg ccaggcaaat ctcacaagag
      121 ataagtaacc gtgaaggtgc tgtcagtcgt gtacaacagg gcctagacag ttatcagcgg
      181 cgattacaaa atgctgaagg gagttacagc agcttacaac aaactgttag tggtttacag
      241 tctgatgtta atagtccaaa cagtaagctt aattctcgga ttagccaatt agctagtcaa
      301 attgaccaac gagtcacaag agccgatgtg acaagcatca ttaaccagtc tggggacagt
      361 atcaagttag ccatacagag agctggtggg attgatgcta agatgtccgc aaaagagatt
      421 gtctcagcca taaacctcaa tggctacggt gtcagaattt ctggtgagcg tattgcttta
      481 gacggcaata ccacggttaa cggggctttt ggcgcaaaaa ttggtgagtt tatcaagcta
      541 aaagccgacc agattatcgg tgggacaatc gatgcaaaca aaatcaatgt gattaatctc
      601 aacgctagca gtattgttgg tttagacgct aattttatta aagcaaggat tgagtatgcg
      661 atcacaagtt tgcttgaggg taaagttatt aaggctcgta atggtgcgat gacaatagac
      721 ttgcaaagcg gtcaaatcaa ccattacaca aatgagtcag ccatgagacg tatcgatagc
      781 agtacagcta gtcagtttat aaagatgaca aagtcaggct ttatatctga gataggtaac
      841 atgcaagctg caatgacggt tataggctct aatagcgatg ggtcagaaaa ccatgaaaat
      901 aaaaccttcg gaggcataag aatttggaac gggaagtcat cttatcaatc gacaagtttt
      961 gttgaattag tcggtaaccg tgtagcaatc tatggaaata aaaatcgtag tccatggctc
     1021 tttgactcaa caacgtcagg atatgcttac ctcattccac agaatgaaag tggtataaag
     1081 catgccatag ggagagctga tcgtaagata gaccaaatcc acgttggaga tatctatgtg
     1141 caaggcgaac gtgtcgctat gatgttaaaa gatttagcga ataggattgg ctatataggt
     1201 acaggtggct gggctaaccg cataggataa attaggagaa acaatgcaag aaaaattatt
     1261 aggaaaaatt attaacgatt taacacttaa agtcgctaat ttaacgctgg aaaatgctca
     1321 attaaaagca cagcatgaaa tcgaattgga agaattaaac gcacaattgg atgaagcaac
     1381 agcaccgaag gaagaaggta aataaacatg agaaattgga aagtaacagg aaactaccca
     1441 cagtgggacg gtacaggagc agtcattgat acgcaggtaa ttattacaga tgacaggggt
     1501 gcagtcatcg cagagaagat caaaaaagat ttgagaacag ctaatgatgc agaaattatc
     1561 gaggctgctt tagaggagtt taaaaagact gcttacgtcg aaatcgctat gggcgaagcc
     1621 gtgcaaaaag tagacgacct tgaaaaaatc tcacaggaaa ctgctaagac tgccaaaact
     1681 gctcaaacag ctgctggact agctaaggtg tccgcagagc gcacgcaaaa gatgattaac
     1741 ttacaaacga tccacatgtt aacgagcggc ggcaagattg atcctgacat ttataaaggc
     1801 atgcttgagc taatcgagcc agccaaaaaa ggtgagtatc aagcgtatga tgtctttacg
     1861 gtggtcgaca gtactaaaga ggaagacggt gaagcaggcg aagggaacct agtcttcgta
     1921 cacgttaacg agccgtttac ttatgaggcg caaactctta aagatttgga atcagaggat
     1981 aaagtcacag tcattaaata tgcggatttg gttaaacaag att
//
LOCUS       DATWEK010000100         1768 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.100, whole genome shotgun sequence.
ACCESSION   DATWEK010000100 DATWEK010000000
VERSION     DATWEK010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1768
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.100"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            89..1480
                     /locus_tag="VCR92_001889"
     CDS             89..1480
                     /locus_tag="VCR92_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEP4268916.1"
                     /translation="MTIFRKKKKYSNKTEMQRHFKVIDLVFLGLGSMVGTGIFTVTGI
                     GAAKYAGPALTISIIISAIAIGILALFYAEFASRMPSNGGAYSYVYATLGEFPAWLVG
                     WYIIMEFLTAISSVAVGWGSYLKGLLANYNIVLPNALNGTFNLKNGTYIDILPVLVMF
                     FVTGIVLMNSKLALRFNSFLVILKFSALALFIFVGIFFIDHNNWSHFAPYGVGQITGG
                     KTGIFAGASVMFFAFLGFESISMAVDEVKEPQKTIPKGIILSLIIVTALYIVVTTILT
                     GIVHYTKLNVPDAVAFALRNIRLYWAADYVSIVAILTLITVCISMTYALARTIYSISR
                     DGLLPKSLYTLTKKNKVPQNATLVTGLLAMICAGIFPLSSLAEFVNICTLAYLIILSG
                     AIIKLRRIEGEPKANEFKTPLVPFLPMLAIIICLSFMSQYKAFTWIAFAIATIIGTLI
                     YLAYGYTHSIENK"
BASE COUNT          566 a          258 c          295 g          649 t
ORIGIN      
        1 gtttcagtca accaataaga tgaaatttac aatcattact aactatgata cacttagtag
       61 aaaatcattt actatagaag gtgataacat gactattttt cgtaaaaaaa agaaatattc
      121 caataaaaca gaaatgcaaa ggcacttcaa agttattgat ttagtttttt taggcctagg
      181 ttcaatggtt ggaacaggta tctttacagt tactggcata ggcgctgcta agtatgcagg
      241 tcctgcttta acaatatcga ttatcatttc cgcgattgct attggaattt tagccttatt
      301 ttatgcagaa tttgcgtctc gtatgccttc taacggtggt gcttatagtt atgtttatgc
      361 aaccttggga gagtttccag catggcttgt tggctggtat attattatgg aatttttaac
      421 agctatatct agtgttgctg ttggctgggg aagttattta aaaggattac ttgccaatta
      481 taatatagta ttaccaaacg ctttaaatgg cacgttcaat cttaagaatg gaacttacat
      541 agatattctt cctgttttag tgatgttttt cgtgacaggg attgtcctaa tgaattcgaa
      601 attagccctg agattcaata gttttttagt tattttaaaa ttttcagcac tggctttatt
      661 tatctttgta ggcatttttt ttattgatca caataattgg tctcattttg ctccatatgg
      721 tgtaggacaa attactggag gtaaaacagg tatctttgct ggtgcttctg ttatgttctt
      781 tgcattttta ggatttgaat ctatttcaat ggcagttgat gaagtgaaag aaccacaaaa
      841 aacaattcct aaaggtatca ttttatcttt gattattgta acagcactct atatagttgt
      901 caccactatt ttaacgggaa ttgtacacta cactaaatta aatgttccag acgcggtggc
      961 ttttgcttta agaaatatta gactttattg ggcagctgac tatgtgtcga tagttgctat
     1021 tttgactctt attacggtat gtatttctat gacctatgca ttagctagaa caatttacag
     1081 tattagtaga gatggtttat tacctaaatc actttatact ctcactaaaa aaaataaagt
     1141 gcctcaaaat gctactcttg tcactggact acttgctatg atttgtgcgg gaatatttcc
     1201 tttatcgagt ctagcagagt ttgttaatat ttgtacttta gcatatttaa ttattctgtc
     1261 gggtgcaatt attaaactca gaagaataga aggagaacca aaagcaaatg aatttaaaac
     1321 tcctctagta ccattcctac caatgttggc aattatcatt tgtctatcat ttatgagcca
     1381 atataaagct tttacttgga ttgcttttgc tattgccaca attattggga cattaatcta
     1441 cttagcttat ggttatactc attcaataga aaataaataa tgttttgata ataagatttg
     1501 acattacatt atagactata atgtttagaa gtaaatgagt agtaaaatca atacctactt
     1561 acttatcaaa gttgtaatat ttaaaattac ccaaccccta gagaattgat tagtctctag
     1621 gggttgattg gtacaatgac atagactcta aaacgatttt aatactaaat atgatagata
     1681 taactttcaa aaaagaaaat tagttcattt ttgttacaca ataaaatttg ttatttagca
     1741 gtaatataat tgaaaaacag aaacattt
//
LOCUS       DATWEK010000101         1761 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.101, whole genome shotgun sequence.
ACCESSION   DATWEK010000101 DATWEK010000000
VERSION     DATWEK010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1761
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.101"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            124..765
                     /locus_tag="VCR92_001890"
     CDS             124..765
                     /locus_tag="VCR92_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEP4268917.1"
                     /translation="MKDLLKQYQAKPLGEEKRYAVFLPLILVNDDWHVLYEVRSQHIS
                     QPGEVSFPGGQVENQETLQEAAIRETVEELTVDASQIQLWGEIDYLVQSSRTIHCFVG
                     QLVVDDWKSIQPNEEVDKVFIVPLRQLLFTDPVYYRLEATPIETTDFPFDRIRNGKYY
                     QFSQEYRSIPFYENLEETIWGMTAQFTKCLTDILNDESIAKKNPSDIENSKGR"
     gene            complement(812..1654)
                     /locus_tag="VCR92_001891"
     CDS             complement(812..1654)
                     /locus_tag="VCR92_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEP4268918.1"
                     /translation="MVSFISRVFKGMIIALGFILPGVSGGVLAAILGIYERMISFLAH
                     MRDNFIENVLFFLPVGIGGILGIALFSFPVEFLLKHYQVSVLWGFAGAIVGTIPSLIK
                     ESTKQSQRDKADWLWLVLTFVISGLGLYFLNDLIGTLPANFLTFILAGALIALGVLVP
                     GLSPSNLLLILGLYGPMLIGFKSLDLLGTFLPIAIGGVLAILAFSKSMDYALQHHHSK
                     VYHFIIGIVLSSTLLILIPNSSSPESISYSHAGILTWLMAFVLFALGIWLGLWMSQLE
                     EKYK"
BASE COUNT          637 a          311 c          336 g          477 t
ORIGIN      
        1 ttttatatat aaaaaaataa catatatatc aaaaatcact aactaggagt aataaattga
       61 ccaaaaagct aggattggtt atgatgaaga taagattaac ggaaagagaa attagggaag
      121 gctatgaagg acttattaaa acagtatcag gcaaaaccac taggagagga gaagcggtac
      181 gccgtatttt tacctcttat tcttgtcaat gatgactggc atgtcttata tgaagtcaga
      241 agtcagcata tttcacaacc gggggaagtt tctttcccag ggggacaagt agaaaatcag
      301 gagacacttc aagaagctgc tatccgagaa acagttgagg aattgactgt tgatgcgtcc
      361 cagatccagc tatggggtga aattgattat ttagtacagt cttctagaac tattcattgt
      421 ttcgttggtc aattagtcgt tgatgactgg aaaagcatac agcctaacga agaagttgac
      481 aaggtcttta tagtaccttt acgtcagcta cttttcactg atcctgtcta ttatcgttta
      541 gaagccactc ctattgagac aacggatttt ccttttgacc gtattcgtaa tgggaaatac
      601 taccaattta gtcaagagta ccgtagtatt ccgttttatg aaaatctaga agaaaccata
      661 tggggaatga ctgcccagtt tactaagtgt ttaaccgata ttctaaatga tgaatcaatt
      721 gcaaagaaaa acccctcaga tattgaaaat tctaagggga gatagagcac tagtttgttg
      781 gcgtcaactt tttgtcaaca aactgtaaag gttatttgta tttttcttct aattgactca
      841 tccaaagtcc gagccaaata ccaagagcaa ataacacaaa ggccataagc caggttaaga
      901 tacctgcatg actgtaggaa atggattcgg gactactact atttggaata agaattaata
      961 gcgtgctgga taatacaata ccaatgataa agtggtaaac ttttgaatga tggtgctgta
     1021 aagcataatc catactttta gaaaaagcca agatggctag gactcctccg atagcaatag
     1081 gtaagaaagt ccctaataaa tccaaagatt tgaaccctat taacatagga ccatagagtc
     1141 ctaagataag taagagattt gacgggctta gtccagggac cagtactcct aaagcaatta
     1201 aggcacctgc taaaataaag gttaaaaagt tagctggtaa ggtaccgatt aagtcattta
     1261 agaagtaaag acctagtcct gaaataacaa aggtaaggac tagccatagc cagtcagctt
     1321 tgtctctttg agactgcttg gttgactcct taatcagact aggaatagtg ccgacaatag
     1381 cgccagcaaa tccccataag acgctaactt gatagtgctt aagcaaaaac tcaacgggga
     1441 aagaaaagag agcaatacct aaaataccac caattcctac tggtaagaaa aataagacat
     1501 tttcaataaa gttatccctc atatgagcta aaaaggaaat cattcgctca tagattccta
     1561 aaatggctgc gagaacacca ccggatacac caggtaaaat aaaacctagt gcaataatca
     1621 tgcctttaaa aactcttgaa ataaatgaaa ccattgttgc ctcctgaaaa gaatgatttt
     1681 attgtatcat aaatttaaag aattgctgac acaaagctgc atatccctac taaaataatt
     1741 gttcctaata aataatacat t
//
LOCUS       DATWEK010000102         1759 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.102, whole genome shotgun sequence.
ACCESSION   DATWEK010000102 DATWEK010000000
VERSION     DATWEK010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1759
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.102"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(21..359)
                     /gene="cadX"
                     /locus_tag="VCR92_001892"
     CDS             complement(21..359)
                     /gene="cadX"
                     /locus_tag="VCR92_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cd(II)/Zn(II)-sensing metalloregulatory
                     transcriptional regulator CadX"
                     /protein_id="HEP4268919.1"
                     /translation="MKKDSICQVGVINQQNVTTATNYLEKEKVQKSLRILSKFTDNKQ
                     INIIFYLLAVEELCVCDIACLLNLSMASASHHLRKLANQNILDTRREGKIIYYFIKDE
                     EIRDFFNQLG"
     gene            complement(371..985)
                     /locus_tag="VCR92_001893"
     CDS             complement(371..985)
                     /locus_tag="VCR92_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEP4268920.1"
                     /translation="MIQNVVTSIILYSGTAVDLLIILMLFFAKRKSRKDIINIYLGQF
                     LGSVSLILLSLLFAFVLDYIPSKEILGLLGLIPIFLGLKVLLLGDSDGEAIAKEGLSK
                     DNKNLIFLVAMITFASCGADNIGVFVPYFTTLNLANLIVALLTFLVMIYLLVFSAQKL
                     AQVPSVGETLEKYSRWFIAVVYLGLGMYILIENNSFDMLWAVLG"
     gene            complement(1278..1427)
                     /gene="rpmG"
                     /locus_tag="VCR92_001894"
     CDS             complement(1278..1427)
                     /gene="rpmG"
                     /locus_tag="VCR92_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEP4268921.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVT
                     FTEVK"
     gene            complement(1443..1625)
                     /gene="rpmF"
                     /locus_tag="VCR92_001895"
     CDS             complement(1443..1625)
                     /gene="rpmF"
                     /locus_tag="VCR92_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEP4268922.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVQFDETTGDYSRSHRVSL
                     KGYYKGRKIAKANEAK"
BASE COUNT          582 a          292 c          288 g          597 t
ORIGIN      
        1 gaaagtagta aaaatagttg ttatcctagt tgattaaaaa aatctctgat ttcctcatct
       61 tttataaaat aatatataat tttcccctct cttctagtgt ccaagatgtt ttgattggct
      121 agtttacgaa gatggtggga ggcagatgcc atactgagat ttaataaaca ggctatatcg
      181 cagacacaga gttcttcgac ggcaaggaga taaaagatga tatttatctg tttattatcg
      241 gtaaattttg ataaaatacg aagtgatttt tggacttttt ccttttcaag gtagttcgtt
      301 gcggttgtaa cattttgttg atttataaca cctacttgac agatactatc ttttttcata
      361 attttttctc ctagcctaac acagcccata gcatgtcaaa gctgttgttt tcaatcagga
      421 tatacatccc caatcctaaa tagacaacgg caataaacca tctgctatat ttttccaaag
      481 tttctccaac agaagggact tgtgccaatt tttgggcaga aaaaaccaag agataaatca
      541 tgactagaaa ggtaagtaaa gccactatca aattcgctaa atttaaggta gtaaaatatg
      601 ggacaaagac accaatattg tcagcaccac aacttgcaaa agtaatcata gcgactagaa
      661 aaatcaggtt tttattatct ttgctcaaac cttctttggc aatagcttct ccatcagaat
      721 ctcctaaaag caaaactttg aggcctagga aaattggaat caaaccgagc aaacctaaaa
      781 tctctttact aggaatataa tctaagacaa atgcaaaaag caaacttagc aatattagac
      841 taacagagcc tagaaattgt cctaaataga tgttaatgat gtcttttctg ctttttcttt
      901 tggcaaaaaa taacattagg ataataagta agtctacggc tgtcccagaa tacaggatta
      961 ttgaagtaac aacattttga atcataaaac acctcattca aatatatttt tgaatgaatt
     1021 ttaacattaa actttgtaga tgtcaatttc agctacacca aaatatagat aagaagttag
     1081 tgtaccaaat ataaaaaagc cctgccatcc aaatgataac agggcttaac ttcaatatcc
     1141 aaatgatata ttcatctaaa aaaggtagag taaaaggtag agttcttatt gatttatatt
     1201 acaatgtaat gaacttcaaa aattcaaaaa tcgcttaaaa tcaacgtttt gacgtctaat
     1261 gacgtgtagt gaacccctta cttaacctct gtaaatgtaa cgtgtttacg taattttggt
     1321 gagtattttt tcaattgaag acggtctgga gtgttacgtt tgttttttga agtaaggtac
     1381 aagcgttcac cagattcttt atgttcaagt gtaatattta cgcgcatggt atctcccttc
     1441 tattatttag cttcgttagc tttagcgatt ttacgtcctt tgtagtatcc tttaagggat
     1501 acacggtgag aacgtgagta atctccagta gtttcgtcga attgtacaga tggagctgtc
     1561 aatttgtagt gtgtacgacg tttgtttttc ttcgcttttg acgtgtgacg tgcaggtact
     1621 gccattttct tattcttcct ttcgatgtgt aagttttgat tttcatcaac ttcactatga
     1681 taacatatct tttttgtaaa gtaaagttac ttgacaaaac tttttatttt tacaatttca
     1741 tggtgaaaat actatcaaa
//
LOCUS       DATWEK010000103         1715 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.103, whole genome shotgun sequence.
ACCESSION   DATWEK010000103 DATWEK010000000
VERSION     DATWEK010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1715
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.103"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..781
                     /locus_tag="VCR92_001896"
     CDS             <1..781
                     /locus_tag="VCR92_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HEP4268923.1"
                     /translation="GNILVYGRLKYFKEGISLYYIGEYLAECLLIEHSDTLLIHAAAV
                     YNPLSGHSILLLGDKGAGKTTVAIRLCIEHGYHLIGNDQVIFGSNSGILLTYAGTSFF
                     KIRRTAVLSDNLLFKLFSKFFNRSLQFNKASWDDKISIFPKELGIRTCNFSTEISKIY
                     YIKTDKKEKQIYHSIWSDSLASLYLNELLGRHISGQVACFQSDNGKYFSTMPLINYEK
                     NNRVREQIVKGIFAKQKLFKITAATPAKIAEAIIENVKKNS"
     gene            836..>1715
                     /locus_tag="VCR92_001897"
     CDS             836..>1715
                     /locus_tag="VCR92_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEP4268924.1"
                     /translation="MFVIGIPTLNEADNISRLVKQIDEYAVNLGKEIIIINSDSKSTD
                     GTPQIFLETKTYNTKVSIVSEAKGKGYNVRNIFEYAINHVPNFSGLILIDGDVVSMKK
                     MWLEKMFIAIESGNDLIIPNYARKSFEGNATNHFIYPMLVKFFKRDMPYQCISGDFGF
                     SRGLIKDLTLKCNWHKYTLGYGIDIFLTLTAILKSYKIKEIDLQSKIHKKSFEKIEKI
                     FLEVSQSFFETINDNSLNQDKLRLNINFESHSRQFIKSSDILSSNDIENLKLRALFLL
                     QEEKQYPHGLSEVEWDG"
BASE COUNT          635 a          202 c          315 g          563 t
ORIGIN      
        1 tggaaatatt ttagtttatg gaagattaaa gtattttaaa gaaggaattt cattatacta
       61 cattggagag tacttagctg aatgtctctt gattgaacat agtgacacct tattaattca
      121 tgcagcagca gtttataatc ctttatctgg ccattcaatt ttactattag gagataaagg
      181 tgctggaaaa actacggttg caataaggct gtgtatagaa catgggtatc accttattgg
      241 taatgaccaa gtaatatttg gttcgaactc tggaatacta ctaacttatg cagggacatc
      301 tttctttaaa ataagaagga cagctgtttt gtcggacaat ttactgttta aattatttag
      361 caaatttttt aaccgttcat tacaatttaa taaggcaagt tgggatgata aaatttcaat
      421 tttcccaaag gagttgggaa tacgaacttg taatttttct actgaaatct caaaaattta
      481 ttatataaag acagacaaga aagaaaagca aatttatcat tcaatttgga gtgatagttt
      541 agcaagtcta tatctaaatg agctattggg aaggcatatt tctggacagg ttgcatgttt
      601 tcaatcagat aatggaaaat atttttctac aatgcctttg ataaattatg aaaaaaataa
      661 tcgggtacga gaacagatag tgaagggtat tttcgctaaa caaaaattat ttaaaattac
      721 agcagctacg ccagctaaga ttgcagaagc gattatagaa aatgttaaga aaaactcata
      781 gtgtgtgtga atttggggat taatatgaag tattgaaaaa ggagtaagag taattatgtt
      841 tgtgataggc attccaactt taaatgaggc agataatatc agtagattag ttaaacaaat
      901 tgatgagtat gctgtaaatt tagggaaaga aattattatt attaattcgg atagtaaaag
      961 tacagatgga actccgcaga tttttttaga aaccaaaact tataacacca aagtttcgat
     1021 agtatcagaa gctaaaggaa aaggttataa tgtgagaaat attttcgaat atgcaataaa
     1081 tcatgtgccg aatttctccg gtttaatttt gattgatgga gacgttgtct caatgaaaaa
     1141 aatgtggtta gaaaagatgt ttatagcaat tgaatctgga aatgatctta taatcccaaa
     1201 ttatgctaga aaatcttttg aaggaaatgc gacaaaccat tttatttatc ccatgttagt
     1261 gaaatttttc aaacgtgata tgccttatca atgcatctct ggtgattttg gattttcaag
     1321 aggattgata aaagatttaa ctttgaagtg taattggcac aaatatacat taggttacgg
     1381 gatagatatt tttttaacct taacagctat attaaagtca tacaaaatta aggaaatcga
     1441 tttacaatca aagattcata aaaaaagctt tgagaagatt gaaaaaattt ttttagaagt
     1501 ttcacaaagt ttcttcgaaa ctattaatga taattctttg aatcaagata agttacgttt
     1561 aaatataaat tttgaaagtc attcaagaca gtttattaag tccagtgata tcctatccag
     1621 caatgatatc gagaatttaa agttaagagc gttgttttta ttacaggaag aaaaacagta
     1681 tccacatggg ctgtcagagg tagaatggga cggaa
//
LOCUS       DATWEK010000104         1659 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.104, whole genome shotgun sequence.
ACCESSION   DATWEK010000104 DATWEK010000000
VERSION     DATWEK010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1659
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.104"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..1242
                     /locus_tag="VCR92_001898"
     CDS             <1..1242
                     /locus_tag="VCR92_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4268925.1"
                     /translation="GKNEFEILYKRSSDERANWYISHLLTHDFAVKELRLGTLESYFL
                     KKYDKNNQLFINQENSINRSKMKYGIVLGVLEIAIQSIIMFLAVREAFLGILLVGNVT
                     TFIRSLSTMQTSTQNIVNNIYSFYNGSLYMELLYDFTHDELVHNPIIESTVDTIQSVE
                     FERVSFSYNGKDNVINDISFSIKAGERLAIVGENGSGKSTIFKLACGLYDNYEGNIYI
                     NGINLRSIQKKSYYKRISALFQDFLKYELTLRENVGLGELSKLYSDEDLISALKYTGV
                     DSIFYFNQEKLNQIDLEQQLGNWFEDGRQLSGGQWQKIALSRVYLKEADCYLLDEPSS
                     ALDPESETKIFKTFFELSQNKIGIFITHKPSITQSVNKILYLDNGCIAETGSFADLNI
                     KGMKFKNLLDKEIGATYDTSN"
     gene            1226..>1659
                     /locus_tag="VCR92_001899"
     CDS             1226..>1659
                     /locus_tag="VCR92_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEP4268926.1"
                     /translation="MTPQIKQIVDYIADSFINYEQIVAESENKVLINIESKYRNTFFD
                     KSLSHGVPSLILMYSSLYKVTKDERYLTFSNIYVEKLVDIISRDGIESPSLYAGTAGI
                     ALAIKEASISGKYYPKLLSSLNCLLKEQIKDKLVVSFSNIEKG"
BASE COUNT          619 a          186 c          306 g          548 t
ORIGIN      
        1 ggtaaaaatg aatttgagat actatataaa aggagtagcg atgagagagc aaattggtat
       61 attagtcatc ttttaacaca tgattttgct gtcaaggagt tgaggttagg tacgttagaa
      121 agttattttc taaaaaaata tgataaaaat aatcaattat ttattaatca ggaaaatagt
      181 ataaatagat ctaaaatgaa atacggcata gtattaggtg tattggagat tgctatacaa
      241 tctattatta tgttccttgc agttagagaa gcatttctag gaatattatt agttggaaat
      301 gtaactactt ttataaggtc tttatctaca atgcaaacaa gtacacaaaa tatagtaaat
      361 aatatctatt ctttctataa tggttcattg tacatggagt tattgtatga ttttacgcat
      421 gatgagttag tacataaccc tataatcgaa agtacggttg atacaattca gtcagttgaa
      481 tttgaaagag tttctttttc atataatggt aaggataatg taataaacga tataagtttt
      541 tcaattaaag caggagagag gttagcaatt gttggtgaaa atggttctgg aaaaagtacg
      601 attttcaaat tagcctgcgg tctttacgat aattatgaag gcaatatata tataaatggt
      661 attaatcttc gttcaataca gaaaaagtca tactacaaga gaatatccgc attgttccaa
      721 gattttttaa agtatgaatt gacactgcgt gaaaatgttg gattgggtga attatcaaag
      781 ttatatagtg atgaggattt aataagtgca ctgaagtata caggagttga ttcgatattt
      841 tactttaatc aggaaaaatt aaatcagata gatctggaac agcaattagg gaattggttt
      901 gaggatggga gacagttatc tggtggacag tggcaaaaaa ttgcattatc aagagtatat
      961 ctcaaagaag cggattgcta tttgctagat gagcctagtt ctgcgttaga tcctgagtct
     1021 gaaacaaaaa tttttaaaac attttttgaa ttatcgcaaa ataaaattgg tatttttatt
     1081 acgcataagc caagcattac tcaatctgtg aataaaattt tgtatctaga taatggatgt
     1141 atagctgaaa caggaagttt cgctgattta aatattaaag gaatgaagtt taaaaactta
     1201 ttagataaag aaattggagc cacatatgac acctcaaatt aaacagatag tagattacat
     1261 tgcagatagt tttataaatt atgaacagat agtagctgaa agtgagaata aagtactaat
     1321 taatattgaa tctaaatata gaaatacctt ttttgataaa tctctgagtc atggtgtgcc
     1381 atcattaatc ttaatgtata gttcactata taaagtgaca aaagatgaga gatatctaac
     1441 attctccaac atatacgttg agaaattagt agacataatc tctagagatg gtatagaatc
     1501 tccgtctctc tatgctggca ctgcaggtat tgcattagct attaaagaag cgagtatatc
     1561 tggaaagtat tatccgaaat tattatcatc cttaaattgt cttctaaaag aacaaattaa
     1621 agacaaattg gtagtaagtt tttctaatat tgagaaagg
//
LOCUS       DATWEK010000105         1458 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.105, whole genome shotgun sequence.
ACCESSION   DATWEK010000105 DATWEK010000000
VERSION     DATWEK010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1458
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.105"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(170..1291)
                     /gene="mnmA"
                     /locus_tag="VCR92_001900"
     CDS             complement(170..1291)
                     /gene="mnmA"
                     /locus_tag="VCR92_001900"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEP4268927.1"
                     /translation="MTDNSKIRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDT
                     DEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGTVHMLRGADNGKDQTYFLSQLS
                     QEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQ
                     KGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQ
                     GFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVAVHVRGDKAEVVFA
                     EPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI"
BASE COUNT          456 a          311 c          237 g          454 t
ORIGIN      
        1 taatgactca acttttacga actattttta aaaataatgt gattatattt aaaatataca
       61 gatatcataa attaatccat taacgcatga ttggttttta taaataatat catatgatgt
      121 ataaggaatt gttgaatgtc cctttctttt tatcttaata aaagattcat taaatgtact
      181 gacaaggctg cccattttta taagccatgt caatcatacc accaccaagg cattcttttc
      241 cgtcatagaa aacaacagct tgaccaggag taatcgcgcg ctgtggctct gcaaaaacaa
      301 cttctgcctt atctcctcga acatgcaccg ccacgtgtga atcgggttga cgatagcgaa
      361 atttagcagt acattcaaat gtgaactctt ctggcatctc acgtgtaaaa tggatgactg
      421 aggcgtcaag actatttgac attagggctt catggtagaa accttgacca acgtataaaa
      481 tattttgcga caaatcttta ccgacaacaa accaaggttg attatcccca ccatgctgac
      541 caccaatgcc cagaccacca cgctgaccaa tagtataata cataagaccg gcatgttctc
      601 ccatatcgcg accatcaata gtcatcatgc gacctttttg tgccggtaag tactggctca
      661 aaaactgttt gaaattcttt tcaccaataa aacaaatacc tgttgaatct ttctttttag
      721 ccgttgcaag tcctgctcgc tcagcgattt ctctaacttc tgacttttgc aaatgaccaa
      781 gggggaataa agtcttttgt agttgttcct gtgatagttg acttaaaaag taggtttggt
      841 ctttgccatt atcagctcca cgtaacatgt gaaccgtacc attttcatca cgcttgactt
      901 gagcatagtg tcccgttgct acataatctg cacctaaagt catggcatag tcaaggaaag
      961 ctttaaattt tatttcctta ttacacatga catcgggatt tggagtacga cctgctcggt
     1021 attcggccaa gaaatattca aatactctgt cccaatattc tttttcaaaa ttgactgagt
     1081 agtaaggaat accgatttga tcagcaacgg ctgctacatc tttgtaatct tcagtagctg
     1141 tgcaaacacc aaattcatct gtatcgtccc agtttttcat gaagacacca ataacatcat
     1201 aaccttgctc ctttaaaagt agagctgtta cagatgaatc aacgccacca ctcataccaa
     1261 cgacaacacg tatctttgag ttatctgtca taaaaaattc tcccatcaat aataagatag
     1321 aaaaagataa tcatcatatt atgaatatta tgattctttt tcttatcagt taacgtacga
     1381 ttgaaggtcg tcgttttcaa aagtcgattt gaaggtcgat tttgaagcgc catcagcgca
     1441 aaccttatta taacaatt
//
LOCUS       DATWEK010000106         1418 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.106, whole genome shotgun sequence.
ACCESSION   DATWEK010000106 DATWEK010000000
VERSION     DATWEK010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1418
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.106"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..281
                     /locus_tag="VCR92_001901"
     CDS             <1..281
                     /locus_tag="VCR92_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268928.1"
                     /translation="YKRFINFEDDFDYRKQAVKLAMAFQIAYLDVSGIMTADDKKTMT
                     SVSIGRTSINYGSSVGGSDGQQYNLSLDAENVLKQAGFSLVVGVDYDR"
     gene            271..597
                     /locus_tag="VCR92_001902"
     CDS             271..597
                     /locus_tag="VCR92_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003108661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEP4268929.1"
                     /translation="MIDKRLLQDTINVQKVQKKDDFGDLAYSAPFAVKSVRFDRYVSV
                     KGTNNSKTKDKTGTVFIYPAVSKVDVDDSWLEATINDGNRDYIVKSIQPNYLNGKLFS
                     YEIGVV"
     gene            597..947
                     /locus_tag="VCR92_001903"
     CDS             597..947
                     /locus_tag="VCR92_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEP4268930.1"
                     /translation="MSFFVRTKTDISRVEKKVSNDNILKGKRALANQVLLDADKYIPK
                     EDGALRASGQTAMDGSNVSWNTVYARAQYYGTNGIVTFNHYTTSGTGKLWYDTAQKAN
                     SDKWKRVAAKGMGL"
     gene            947..1345
                     /locus_tag="VCR92_001904"
     CDS             947..1345
                     /locus_tag="VCR92_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEP4268931.1"
                     /translation="MQDNKNFQEVLLKHINSFDRLPLKARLDYFNEDEDDLVINAIPG
                     GTIDKEFMDGTREVSLPFEIAVKSRTNKKASDIIWFLNGELSAFDIDLPSTDNSYTFL
                     SLLVEKPGINGRDEQGFFVYTLQLTAKLEI"
BASE COUNT          478 a          233 c          310 g          397 t
ORIGIN      
        1 tctacaagcg ttttatcaac tttgaagatg attttgatta tcgtaagcaa gcagtcaagc
       61 ttgcgatggc atttcagatt gcttacttgg atgtttcagg catcatgaca gctgatgaca
      121 aaaaaacaat gacaagcgtg tctattggac gtacctcaat caattacggc tcatctgtgg
      181 gcggttcaga cggtcagcaa tataacttat cgcttgatgc ggagaacgtg cttaaacagg
      241 caggatttag ccttgtggtg ggggttgatt atgatagata aacgcttatt gcaagacact
      301 attaatgttc aaaaagtaca aaagaaagat gattttggag atttagcata ttcagcaccg
      361 ttcgccgtta aatcagtcag atttgacagg tatgtttctg tcaaaggtac gaataactct
      421 aaaactaaag ataagacagg tacagttttc atttatccag ctgtttcaaa agtagatgtg
      481 gatgatagtt ggcttgaagc aacaatcaat gacggaaatc gtgattacat tgttaaaagt
      541 attcaaccga actatctgaa cgggaaattg ttcagctatg agattggagt ggtctaatga
      601 gtttctttgt tcggactaaa actgacatta gccgtgttga aaagaaagtg tcaaacgaca
      661 acattctaaa agggaaacgt gcattagcta atcaagtgct tttagatgct gacaagtata
      721 ttcctaaaga agacggtgct ttacgtgcta gcggtcaaac cgctatggat ggaagcaatg
      781 tctcatggaa tacagtatat gcacgagcac aatattatgg cactaacgga attgttacat
      841 ttaaccatta tacaacgtca ggtactggta aattatggta tgacacagct caaaaggcta
      901 attcagataa gtggaaacgt gtagctgcta aaggaatggg gctctaatgc aagataacaa
      961 aaactttcaa gaagtgcttt taaaacatat taatagtttt gacagattac cgttgaaagc
     1021 aagactagat tatttcaacg aggatgaaga tgatttggtt atcaatgcta ttccaggtgg
     1081 aacgattgac aaggaattca tggacggtac gagagaagta agtctaccgt ttgaaattgc
     1141 ggtcaaaagc agaaccaaca agaaagcaag tgatattatc tggtttctaa acggcgaatt
     1201 gtcagcgttt gacattgatt tgccaagtac agataattca tacacttttt tgtccttgtt
     1261 ggttgaaaaa cctggtatca acggaagaga tgagcaaggt ttctttgtct acaccttgca
     1321 actaacagca aaattggaaa tttaaggagg aaattatggc acgtcaaaaa aatgcgaagc
     1381 gacaacattt tatcgcaccg tttaacccag aaacacca
//
LOCUS       DATWEK010000107         1415 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.107, whole genome shotgun sequence.
ACCESSION   DATWEK010000107 DATWEK010000000
VERSION     DATWEK010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1415
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.107"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..281
                     /locus_tag="VCR92_001905"
     CDS             <1..281
                     /locus_tag="VCR92_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268932.1"
                     /translation="YKRFINFEDDFDYRKQAVKLAMAFQIAYLDVSGIMTADDKKTMT
                     SVSIGRTKIDYKTSESTFSGQQYNLSIDAENVLKQAGFSLVVGVDYDR"
     gene            271..597
                     /locus_tag="VCR92_001906"
     CDS             271..597
                     /locus_tag="VCR92_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003108661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEP4268933.1"
                     /translation="MIDKRLLTDTVIVQKVQKENDFGDLTYSEPLTVKHVRFDRSSSV
                     SGANNSKKKDRTGTIFIYPAISGVKVDNSWDEATVSDGANTYIVKSHEPNYLNGKIFS
                     YEVGVI"
     gene            597..944
                     /locus_tag="VCR92_001907"
     CDS             597..944
                     /locus_tag="VCR92_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEP4268934.1"
                     /translation="MFRIRTKADLSGAERKVSDANILRAKRVVANQVLMDTANYIPMK
                     DGDLRASGQIAIDGSAVSWDTVYARAQFYGTNGIVVFRKYTTPGTGKLWYDKSAEANV
                     GKWKRVAAKGMGL"
     gene            944..1342
                     /locus_tag="VCR92_001908"
     CDS             944..1342
                     /locus_tag="VCR92_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEP4268935.1"
                     /translation="MQDNKNFQIVLLKYINSFKQLPLKARLDYFKDNQDDLVVNAIPG
                     GTIEREFMDGTREVSLPFEIAVKSKSNQLASDVIWFLNGELSVFDIDLPSTDDSYTFL
                     SLSVGKPGINGKDEHGYFVYTLQLQAKLEI"
BASE COUNT          462 a          231 c          321 g          401 t
ORIGIN      
        1 tctacaagcg ttttatcaac tttgaagatg attttgatta tcgtaagcaa gcagtcaagc
       61 ttgcgatggc atttcagatt gcttacttgg atgtttcagg catcatgaca gctgatgaca
      121 agaaaacaat gacaagcgtt tctatcggac gtaccaaaat cgattacaag acatctgaga
      181 gcacgtttag cggtcagcaa tataatttat caattgatgc cgaaaacgtt ctgaaacagg
      241 caggatttag ccttgtcgtg ggagttgatt atgatagata agcgtttgtt aactgacact
      301 gttattgttc aaaaagtaca aaaagaaaat gattttggtg atttaactta ttcagaaccg
      361 ttgacggtca aacacgttcg ctttgaccgc tctagttctg tttctggagc gaataactct
      421 aagaaaaaag acagaacagg aacaattttc atttatccag ccatttcggg tgtcaaggta
      481 gacaacagct gggatgaggc gactgttagc gatggtgcta atacgtacat tgttaaaagt
      541 catgagccta attacttaaa tggcaaaatc tttagctatg aagtaggagt gatttgatgt
      601 ttcgtattcg gacaaaggct gatttgagtg gtgctgagcg taaagtatca gacgcaaata
      661 ttttgagagc gaaacgtgta gtagctaacc aggttctgat ggatacagcc aattacatcc
      721 cgatgaagga cggtgatttg cgagccagcg gacaaatagc tatagatggt agtgctgttt
      781 cttgggatac agtatatgca cgagctcaat tttatgggac aaatggcatt gttgtattta
      841 gaaaatacac gacaccaggt acaggaaagc tttggtatga caaatcagcg gaagcaaatg
      901 ttggtaagtg gaaacgtgta gctgctaaag gaatggggct ctaatgcaag ataacaaaaa
      961 ctttcaaata gtacttttaa aatacattaa cagttttaaa caattgccgt tgaaagcacg
     1021 gctagattat ttcaaagata atcaagatga tttggtcgtc aatgctattc caggcggaac
     1081 gatcgagaga gaattcatgg acggtacgag agaagtaagc ctaccgtttg aaattgcagt
     1141 caaaagtaag agtaatcagc tggcaagtga tgtcatttgg tttctgaatg gtgagttatc
     1201 agtatttgat attgatttgc caagcacaga cgactcttac acattcttat ctctttcagt
     1261 tggtaaacct ggtattaatg gcaaagatga acatggttat tttgtttaca cattgcaatt
     1321 acaagcaaaa ttagaaattt gaggaggaaa ttatggcacg tcaaaaaaat gcccaacgca
     1381 aacactttgt agcaccgttt aatccaggaa cgcca
//
LOCUS       DATWEK010000108         1386 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.108, whole genome shotgun sequence.
ACCESSION   DATWEK010000108 DATWEK010000000
VERSION     DATWEK010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1386
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.108"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            329..811
                     /locus_tag="VCR92_001909"
     CDS             329..811
                     /locus_tag="VCR92_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEP4268936.1"
                     /translation="MNERQKRFADEFIKLGNATKAAINAGYSEKYAGANADKLLKNTK
                     IRAYIDDQLSELHKKNIMDAEEALSILSDIARGNRDEEVLMMNPVTGEVKRLRKKADN
                     ATVIKAIQEILKRYPTAKQAEKLELELAKLREQVNANEAQDEQIIIVDEWAEEVDDGL
                     "
     gene            801..>1386
                     /locus_tag="VCR92_001910"
     CDS             801..>1386
                     /locus_tag="VCR92_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEP4268937.1"
                     /translation="MVFNVQKNVNPHFKPVWISSEPYNILKGGRNSFKSSVIALKLVY
                     MMIKYIKKGDTANVVIIRKVANTIRDSVFNKIQWALQLYGVFGGFKTTVSPFKIIHKK
                     TGSTFYFYGQDDFQKLKSNDIGNIIAVWYEEAAEFDSEEDFDQSNVTFMRQKHAKAKC
                     VQFFWSYNPPRNPYSWINKWFETMKIRDEYLCHSS"
BASE COUNT          486 a          235 c          293 g          372 t
ORIGIN      
        1 ataacaatga agatgcagcg ttttacgtca atttgaacac agtcacaagt gaggttatct
       61 caagaacaga tgagtcactt gtcagagtgc tcaaagaggt atatgtatac gagacaatga
      121 acgtgatagg tgctagtcaa aggatttact acaggagtcc aaacagaaca tacaaacatc
      181 tcaacaactg gtttgataac tatttccgtg ctacatacag acatttgtta gctaacgcct
      241 tgaaagaacg gtaaaaagcc acgttaactt gatattacaa tgaaatcatg agtcttaact
      301 catgattttt tgtgtgaaag gagaggtaat gaatgaacgt cagaaacgat ttgcagatga
      361 atttatcaag ctaggaaatg caacgaaagc agcaattaac gctggatatt ctgagaaata
      421 tgcaggcgct aacgctgata agctactaaa aaatactaaa attcgagcgt acattgatga
      481 tcaactttct gaattacaca agaaaaacat catggatgct gaagaggcgt tgagtatact
      541 atcagacatt gccaggggaa atcgtgacga agaagttttg atgatgaacc cagttacagg
      601 cgaagtcaaa aggctcagga agaaagcaga taatgcaaca gttatcaaag ctattcaaga
      661 aattttgaaa cgttatccaa ctgctaaaca agccgaaaaa ttagagcttg aattggctaa
      721 gttgcgtgaa caagtcaatg ctaacgaggc gcaagacgag cagattatta tcgttgatga
      781 atgggctgag gaggtagacg atggtcttta atgttcaaaa gaacgtaaac ccacatttta
      841 agcctgtttg gatatcaagc gaaccttata acattttaaa aggtggacgt aactcgttta
      901 agtcgtctgt aatcgcatta aagcttgtat acatgatgat taaatacatc aagaagggtg
      961 acacagctaa cgttgttatt attcgtaaag tagccaatac aatccgtgac agtgtcttta
     1021 ataaaataca gtgggcgttg caattatacg gcgtttttgg tggttttaaa acgactgtta
     1081 gcccgttcaa gataattcat aagaaaacag ggtcaacgtt ctatttttac ggtcaggacg
     1141 actttcaaaa gctgaaatca aacgatattg ggaatattat cgctgtttgg tatgaagaag
     1201 cagccgaatt tgatagcgaa gaagattttg accagtcaaa cgttactttc atgcgccaga
     1261 aacacgctaa agctaaatgc gtgcaattct tttggtccta taaccctcca cgtaatccat
     1321 acagttggat taacaagtgg tttgagacta tgaaaatccg tgatgaatat ctttgccact
     1381 catcta
//
LOCUS       DATWEK010000109         1379 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.109, whole genome shotgun sequence.
ACCESSION   DATWEK010000109 DATWEK010000000
VERSION     DATWEK010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1379
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.109"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            411..>1379
                     /locus_tag="VCR92_001911"
     CDS             411..>1379
                     /locus_tag="VCR92_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEP4268938.1"
                     /translation="MTDSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVIHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERFIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKILNKNGKPKTRKVELTIWNDKGNVEKWRENFSDLCNEYLAKNKIEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNDLVKTIKEEIKTLK
                     GWIGNLLDNLSTAYEKFKDIERDKVIDNPKLFNLTNYLLTYSEIQKE"
BASE COUNT          643 a          182 c          232 g          322 t
ORIGIN      
        1 ttaaatgatg aagaaataag attaaacata atggaaattt tagaagaaag agtagatgat
       61 gatgtagaaa aatcacctaa agatgaaata acataattgt cccttggtta caagggcgca
      121 attatacacc ctaaagggtg cttgcgtgcc tttagagcaa aacccttgca gggagcaaca
      181 accattcgtt ttttaaaagt caagggtaaa taaactcgct aaggctcgcc attgactttt
      241 aaaatttgaa atgaacaaaa caattaagcc gacatactga aacaacaaaa attaattcag
      301 tagtcggctt tttctattct atcatttcaa aacgctcatt cacaaagagg atataaaaat
      361 ctattaagcc tccacctaaa acaacaaaaa aagaaaggaa gtgataaaaa atgacagaca
      421 gttttcattt ttcagtaaac ataatatcaa gaggaaaagg gaaaagtgca gtagcaagtg
      481 cagcatatat aagtggagaa aaaataaaaa atgaatggga cggagtaatc catgactaca
      541 caagaaaaga aaaaatatta gtaaaaaata taatattgcc tgatcatata ccaaaagaat
      601 ttaatgatag gtctacatta tggaataaag tagaaatggc agaaaaaaat tctaatgcac
      661 aactagcaag acaattcata ataggactac caaaagaatt atctttaagt gaaaataaaa
      721 acctagtcga aagatttata aaagaaaatc taacatcaca aggaatgata gtagattatg
      781 caatccatga tgagagtcaa gacaaaaatg gaaatatcca ttgtcatata atgaccataa
      841 tgcgaccaat aaacgaaaaa ggagagttct tagcaaagtc aaaaaaagaa tatatcctag
      901 atgaaaaagg agaaaagatt ttaaacaaaa atggaaaacc taaaacaaga aaagtagaac
      961 taacaatctg gaatgataag ggcaatgtag aaaaatggag agaaaatttt tcagaccttt
     1021 gcaatgaata tctagcaaaa aacaagatag aaaaaagagt agaccatagg agttttaaaa
     1081 gacaaaattc tgattattta ccgacaatcc atttaggatc agcagcaagt gcaatggaaa
     1141 gaaagggaat agaaactgac aaaggaaact ataatagaga aataagaaaa tataacgacc
     1201 ttgtaaagac aataaaagaa gagataaaaa cattaaaggg ttggatagga aatctattag
     1261 ataacctatc tactgcttat gaaaaattta aggatataga aagagataag gtaatagaca
     1321 accctaaact tttcaatcta acaaattatc tattaactta ttcagaaatt caaaaagaa
//
LOCUS       DATWEK010000110         1312 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.110, whole genome shotgun sequence.
ACCESSION   DATWEK010000110 DATWEK010000000
VERSION     DATWEK010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1312
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.110"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..>1312)
                     /locus_tag="VCR92_001912"
     CDS             complement(<1..>1312)
                     /locus_tag="VCR92_001912"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEP4268939.1"
                     /translation="SALANLAPLVVAVGVAIGATAPAITALGNAISSVVASVGVALPP
                     IIVAISNAITQIGLMLGTILPPIITSLGTAISQIAVAITPIVGIISSAFVQIVTVVSN
                     AIVQIIQALSPFIPAITEMVVAVAPVLSQIVDAFNNLISQISPIIDSITNLFKTLGEQ
                     ISNILDSAKGVITGFGDAVRNVLDGIAGIFDSMGNAALNAGNGVKQMAQGVKMLVDLK
                     LGDLAATLATTASGLGKMASHSAGMSQLGSAMTQVGTGMTQFATGAMISLAALSQFDA
                     VITTLKTNLSLLPAMMTVAGAGFPVFVSQAVAGIAGLSAVNAPIAAFKAQLMSLTPTI
                     LSATAGFAMFGARAMVINGTFTVIGGFISAFNARILSMGAATAMAGASFGALAGRVGA
                     LGGVLSSVSGGFANIGASAASSASQMRSIISATQSVISAFSSMRA"
BASE COUNT          390 a          321 c          277 g          324 t
ORIGIN      
        1 gcgcgcattg agctaaacgc tgaaataaca gactgtgtcg ctgaaatgat tgaacgcatt
       61 tgagacgctg aacttgccgc actcgcacca atatttgcaa aaccgcctga aactgacgat
      121 agaactccac ctaaagcacc tactctacca gctaacgcac caaacgacgc tcctgccatt
      181 gctgttgctg cgcccattga caagatgcgt gcgttaaatg cactaataaa tccaccgatg
      241 acggtaaacg tgccattgat gaccatcgct ctagcaccaa acattgcaaa gcccgctgta
      301 gcagataaga ttgttggtgt taaactcatc aattgtgctt taaatgctgc aattggtgca
      361 ttaacagctg ataatccagc aataccagcg actgcttgag aaacgaatac tgggaaacct
      421 gcaccagcca ccgtcatcat cgctggcaaa agagacaaat tggtcttgag tgttgtaatc
      481 actgcatcaa actgacttaa agcagctaac gaaatcattg cgccagtcgc aaactgagtc
      541 ataccagttc caacttgtgt cattgccgag ccgagctggc tcatccctgc tgaatgacta
      601 gccattttac cgagaccact agctgtagta gctaaagttg ctgctaaatc gcctagtttt
      661 aaatcaacta gcatcttgac accttgcgcc atctgcttaa cgccattacc agcattaaga
      721 gcggcattcc ccattgagtc gaaaatgccc gcaataccgt ctaaaacgtt tcgaacggcg
      781 tcgccgaaac cagtgataac acccttagca ctgtccagaa tgttgctgat ttgctcacct
      841 aacgtcttga acaggttggt gattgagtca ataatcggac tgatttgact gattaggttg
      901 ttaaacgcat ccacgatttg agatagtact ggagctaccg ctacgaccat ctctgtaatc
      961 gctgggataa acggtgatag cgcttgaata atttgaacaa tagcgttaga cactaccgtc
     1021 acaatttgaa cgaaagcact actaataatt ccaacgattg gtgtaatagc aacagcaatt
     1081 tgagagatgg ctgtgccgag agatgtaatg attggtggca aaatcgtacc aagcattaag
     1141 ccgatttgtg ttatcgcatt gctaatagct acaataatag gcggtaaagc cacaccaacg
     1201 gatgcaacaa ccgagcttat tgcattacct aaagctgtga tagctggtgc tgttgcacca
     1261 attgccacac cgactgctac tactaaaggc gctaggttag ctaatgcact tg
//
LOCUS       DATWEK010000111         1308 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.111, whole genome shotgun sequence.
ACCESSION   DATWEK010000111 DATWEK010000000
VERSION     DATWEK010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1308
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.111"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            108..296
                     /locus_tag="VCR92_001913"
     CDS             108..296
                     /locus_tag="VCR92_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4268940.1"
                     /translation="MLITENIAVKVRKKRAVKQLGKVELSKKLGITPPTLSKIEAGNY
                     KAPKRIYASVMEWLAEDY"
     gene            312..878
                     /locus_tag="VCR92_001914"
     CDS             312..878
                     /locus_tag="VCR92_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
                     /protein_id="HEP4268941.1"
                     /translation="MNRQVSIFEEVNDQGGAFQVVTTMTFHDRLLDIYGNIQEPLFRA
                     RDVAEMIDHSKTRNGYYDVQSMLRKVDDDEKVKGVPLEGATKNFRSGQKVWFLTEHGL
                     YEVLMRSSKPKAKEFRKAVKNILKEIRLNGYYMQGELVQNSQPTPDIDDLSYIKQKLT
                     DLQDVDSLQDLRWKMAKLYHVIETLDEY"
     gene            935..1177
                     /locus_tag="VCR92_001915"
     CDS             935..1177
                     /locus_tag="VCR92_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor protein"
                     /protein_id="HEP4268942.1"
                     /translation="MKATTYKELKKWIDEGVDLAELAQGYADKVPSVDREQFEAVTQG
                     IFNVLEGVSLMLDDKVLIYNRKAEQKRLNDIEQGDY"
BASE COUNT          499 a          198 c          277 g          334 t
ORIGIN      
        1 acgaaaaaaa attggatttt tatcttgaca accaaattta tttgcgttaa tatagatttt
       61 gcaaaaataa gacgaaaaaa aattgggttt ttgcaaagga ggaatatatg cttattacag
      121 aaaatatagc tgttaaggtt cgtaaaaaaa gagctgttaa acagttagga aaagtggagc
      181 tttctaaaaa attagggata acgccaccca ctctatcaaa aattgaagct ggcaactaca
      241 aagcacctaa gcgtatctac gctagtgtca tggaatggct agcagaggat tattagaaag
      301 gcaggaacaa aatgaataga caggtcagta tttttgaaga agtcaatgat caagggggag
      361 ctttccaagt tgtaaccact atgacttttc acgatcggct attagatatt tacggtaata
      421 ttcaagaacc gttatttaga gctagagatg ttgcggaaat gattgatcac agcaaaacaa
      481 ggaacggata ttatgacgtt caatctatgc taagaaaggt agatgatgac gaaaaagtta
      541 aaggcgtccc tttagagggt gctacgaaaa atttccgtag cggtcaaaaa gtttggtttt
      601 taactgagca tggactttat gaagtgctta tgcggtcaag caaaccaaaa gccaaagagt
      661 ttagaaaagc agtcaaaaac attctcaaag aaatccgttt gaatggctac tacatgcaag
      721 gagagcttgt ccaaaacagt caaccgaccc cagacattga tgatttaagc tatatcaagc
      781 agaagttaac tgacttacag gacgttgaca gcttacaaga tttacggtgg aagatggcta
      841 agttatatca cgtcatcgaa acactggatg aatattaaga aataagacaa caaaaaaaag
      901 cgcaataata cgcacggata aaggagaaat gattatgaaa gcaacaactt acaaagagtt
      961 gaagaaatgg attgatgaag gtgttgattt agctgagcta gcacagggtt acgctgacaa
     1021 agtacctagt gtagaccgtg aacagtttga agcagtcaca cagggaattt tcaacgtatt
     1081 ggaaggcgta tcgctcatgc ttgatgacaa agtgctaatc tataatcgca aagcagagca
     1141 aaagcgtttg aatgacattg aacaaggtga ttattaatta ataatcaaga gtaacaaaaa
     1201 aagccttgaa ctttggcgag gaacaggctt ttcacttcaa ttaactaaaa ccataaaaaa
     1261 gcaagtatgg gatttagtta ggtatttatt taattatacc acaatcaa
//
LOCUS       DATWEK010000112         1286 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.112, whole genome shotgun sequence.
ACCESSION   DATWEK010000112 DATWEK010000000
VERSION     DATWEK010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1286
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.112"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..>1286
                     /locus_tag="VCR92_001916"
     CDS             <1..>1286
                     /locus_tag="VCR92_001916"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEP4268943.1"
                     /translation="LVVAVGVAIGATAPAITALGNAISSVVASVGVALPPIIVAISNA
                     ITQIGLMLGTILPPIITSLGTAISQIAVAITPIVGIISSAFVQIVTVVSNAIVQIIQA
                     LSPFIPAITEMVVAVAPVLSQIVDAFNNLISQISPIIDSITNLFKTLGEQISNILDSA
                     KGVITGFGDAVRNVLDGIAGIFDSMGNAALNAGNGVKQMAQGIKILVDMPLDDLSATL
                     VKTASGLGKIGSHASTMAQVGTAMTQVATGMAQFALGATISLAALSQFDAVITTLKTN
                     LSLLPAMMTVAGAGFPAFVSQAVAGIAGLSAVNAPIAAFKAQLMSLTPTILSATAGFA
                     MFGARAMVINGTFTVIGGLISAFNARILSMGAATAMAGASFGALAGRVGALGGALSSV
                     SGGFANIGASAASSASQMRSIISATQSVISAFSSMRA"
BASE COUNT          322 a          278 c          308 g          378 t
ORIGIN      
        1 ttagtagtag cagtcggtgt ggcaattggt gcaacagcac cagctatcac agctttaggt
       61 aacgcaataa gctcggttgt tgcatccgtt ggtgtggctt taccacctat tattgtagct
      121 attagcaatg cgataacaca aatcggctta atgcttggta cgattttgcc accaatcatt
      181 acatctctcg gcacagccat ctctcaaatt gctgttgcta ttacaccaat cgttggaatt
      241 attagtagtg ctttcgttca aattgtgacg gtagtgtcta acgctattgt tcaaattatt
      301 caagcgctat caccgtttat cccagcgatt acagagatgg tcgtagcggt agctccagta
      361 ctatctcaaa tcgtagatgc gtttaacaac ctaatcagtc aaatcagtcc gattattgac
      421 tcaatcacca acctgttcaa gacgttaggt gagcaaatca gcaacattct ggacagtgct
      481 aagggtgtta tcactggttt cggcgacgcc gttcgaaacg ttttagacgg tattgcgggc
      541 attttcgact caatggggaa tgccgctctc aatgctggta atggcgttaa gcagatggcg
      601 caaggtatca aaatacttgt tgatatgcct ttagatgatt tgagcgctac tttggttaaa
      661 acagctagcg gtctcggaaa aataggaagc cacgcctcaa ctatggcaca agtaggcaca
      721 gcgatgacac aagtcgccac tggtatggct caatttgctc tgggcgcaac tatttcgtta
      781 gctgctttaa gccaatttga tgcagtgatt acaacactca agactaattt gtctcttttg
      841 ccagcgatga tgacggtggc tggtgcaggt ttcccggcat tcgtttctca agcagtcgct
      901 ggtattgctg gattatcagc tgttaatgca ccaattgcag catttaaagc acaattgatg
      961 agtttaacac caacaatctt atctgctaca gcgggctttg caatgtttgg tgctagagcg
     1021 atggtcatca atggcacgtt taccgtcatc ggtggactta ttagtgcatt taacgcacgc
     1081 atcttgtcaa tgggcgcagc aacagcaatg gcaggagcgt cgtttggtgc gttagctggt
     1141 agagtaggtg ctttaggtgg agctctatcg tcagtttcag gcggttttgc aaatattggt
     1201 gcgagtgcgg caagttcggc gtctcaaatg cgttcaatca tttcagcgac acaatctgtt
     1261 atttcagcgt tcagctcaat gcgtgc
//
LOCUS       DATWEK010000113         1274 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.113, whole genome shotgun sequence.
ACCESSION   DATWEK010000113 DATWEK010000000
VERSION     DATWEK010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1274
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.113"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            54..956
                     /locus_tag="VCR92_001917"
     CDS             54..956
                     /locus_tag="VCR92_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP4268944.1"
                     /translation="MTQQSMLLSIEQVNKSYGKNQVLSDISFDIYKGEICGLVGQNGA
                     GKTTLMRILSGLIGKDSGQIKQLQPYRMGSIIESPTLYPNMTAHDNLYYAALQLRLAD
                     AKERIHEVLELIGLEKVSKKKKVKDYSLGMRQRLAIGLSILDFPEFLILDEPINGLDP
                     AGIKEMRQIILNLRDCYGITILISSHILSELDLVVDRYVIMHKGKVIKSMDKAELKAQ
                     VKVQIALHTSDDQLVKNRLLELGLRVETDGQMLLIKPTLSVMELIKIVLDLPVEIFDI
                     YHHQVSFEHYYLDLLGKDAASPLI"
     gene            969..>1274
                     /locus_tag="VCR92_001918"
     CDS             969..>1274
                     /locus_tag="VCR92_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP4268945.1"
                     /translation="MISYLKADLFRIRQERLALFSCMLLVVIAVGVAYSFRKTPNQVI
                     MIQIINIITDFVTLFFLTPARIFFSDDYNYRTINNVVVKQQNRTLIIIYKLLVSFGLS
                     "
BASE COUNT          413 a          193 c          244 g          424 t
ORIGIN      
        1 ttattatgtg taagatattg tattaatcga taagtacaaa aaaggagcgg aaaatgacac
       61 agcaatcaat gttactaagt attgagcaag taaataaatc ctatggtaaa aatcaggttt
      121 taagtgatat ctcttttgat atttacaaag gagaaatttg cggccttgtg ggtcaaaatg
      181 gtgctggaaa gacaacgtta atgcgtattt tatctggcct aattggaaaa gattcagggc
      241 aaatcaaaca gttacaaccc tatcgaatgg gatcaattat tgagtcaccg acactttatc
      301 ccaatatgac agctcatgat aatctttact atgcagcgtt gcaattgaga ttagctgatg
      361 caaaagagcg catacatgag gttttggaac ttattgggtt agaaaaagtg agcaaaaaga
      421 aaaaggtgaa agattattct ttagggatgc gccaacgttt ggctattggt ctttcgatac
      481 tggattttcc agaattttta atcttggatg aacccattaa tggtcttgat ccagcaggaa
      541 tcaaagaaat gcgtcagatt attttgaacc taagagattg ctatggtatt acgattttga
      601 tttccagtca tattttatca gaattagact tagttgttga tcgttacgtg attatgcata
      661 aaggcaaagt tattaagagt atggacaaag cagagcttaa agctcaagta aaagtacaaa
      721 ttgcccttca tacaagcgat gatcagctgg taaaaaatag acttttagaa ttggggctta
      781 gagttgagac tgatggtcag atgctactaa taaaaccaac tttatcagta atggagctta
      841 tcaaaattgt tctagatctg cctgttgaga tttttgacat ttatcatcat caagtgagct
      901 ttgaacatta ttacctcgat ttgttaggta aagatgcagc atcaccatta atttagaaag
      961 aggtttttat gatttcctat cttaaagcag atttatttcg gatacgccaa gagcgtttag
     1021 ctctattttc ttgtatgcta cttgttgtca ttgctgttgg tgtagcctat agttttcgca
     1081 agacacctaa ccaagtcatc atgatacaaa tcattaatat tattactgat tttgtgacgc
     1141 ttttcttttt aacaccagcc cgtatctttt ttagtgatga ctataactac cgtacgatta
     1201 ataatgttgt ggtcaaacaa caaaatcgta ctttaattat aatctataaa ctgctagtta
     1261 gttttggctt atct
//
LOCUS       DATWEK010000114         1241 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.114, whole genome shotgun sequence.
ACCESSION   DATWEK010000114 DATWEK010000000
VERSION     DATWEK010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1241
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.114"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            71..>1241
                     /locus_tag="VCR92_001919"
     CDS             71..>1241
                     /locus_tag="VCR92_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEP4268946.1"
                     /translation="MIDSLLLKSLHSLLGLTITVCDQNFSVIREYKSDKTISLFYNHY
                     LILSNFSKTQHDFLFHYGSLGELFLVHHIQQYYIIIGPWRSNAIDPLLLKKKLTETQI
                     NASEQDYFIDRLSQLPFFSLSQIRELLIVTNYCLTGVVKDKLSEPLHYYTKGWSNSFD
                     LDKIKQFSKQNMSSYKYQYHFENNILKAVKSGSEFLLKETVEHFSNSIVPIISGDELR
                     SEKNYSIIIYDRLSQATIQAGLDIETAYRARDRFIKETESTISLNEVLKLRDTAILFY
                     TQQVDSLKRHLETPHSQTIVAVIRYLENNLNRFIKTEEIAKECHMSESKLRKLFKQEK
                     HITIQQYFINLKIEAAKQLLDENKKVEEVSNLLGFSTSSNFSRTFKKIVGISPLEY"
BASE COUNT          451 a          210 c          170 g          410 t
ORIGIN      
        1 attattctgt tgactttaaa gaaatcttct ctaaaataga taacatatta aatcaaaggt
       61 ggtaactcat atgattgatt ctttattgtt gaaatcatta cacagtcttc taggtctaac
      121 tattactgtt tgtgatcaaa atttttctgt tatcagagag tataaatccg ataaaactat
      181 ttcacttttt tacaatcatt accttatttt aagtaacttt agtaaaactc aacatgattt
      241 tttatttcat tatggctctt taggagaact ttttcttgtc caccatattc aacaatatta
      301 tattatcatc ggtccctggc gtagcaatgc tattgatcct ttacttctta agaaaaagct
      361 gactgaaaca caaatcaatg ctagtgaaca agactacttt attgatagac tatcccaatt
      421 acctttcttc tcacttagtc aaatccgaga attactaata gtaaccaatt attgtctaac
      481 tggggttgtg aaagataaat tatcagagcc cttacattac tacacgaaag ggtggagcaa
      541 ctcctttgat ctagataaaa ttaagcaatt ttctaaacag aatatgagtt cttacaaata
      601 tcagtatcat tttgaaaata atattctaaa agctgttaaa tcaggtagtg aatttctttt
      661 gaaagaaaca gtggaacact ttagcaattc tatcgtacct ataatcagtg gagatgaatt
      721 gcgatctgaa aaaaactact ccatcattat ttatgatcgt ctctcacagg ctaccatcca
      781 agcaggactt gatatcgaaa cagcttatcg agcacgagat cgttttataa aagaaaccga
      841 gtcaactata agtctaaatg aagttttaaa attacgtgat actgctatct tattctatac
      901 tcaacaagtt gattctttaa aaagacatct cgaaacccct cattctcaaa ctattgtcgc
      961 agtgattcga tatcttgaaa ataatctaaa tcgctttatt aaaacagaag aaatagctaa
     1021 agaatgtcac atgagtgaat cgaagttacg aaaactattt aagcaagaaa aacacatcac
     1081 tattcaacaa tattttataa acttaaaaat cgaagctgct aagcagttac tagacgaaaa
     1141 taagaaagta gaagaagttt ccaatttact tggattttcc acttcttcta atttttcaag
     1201 gacatttaaa aaaatagtgg gaattagccc actagaatat a
//
LOCUS       DATWEK010000115         1235 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.115, whole genome shotgun sequence.
ACCESSION   DATWEK010000115 DATWEK010000000
VERSION     DATWEK010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1235
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.115"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..1091)
                     /locus_tag="VCR92_001920"
     CDS             complement(<1..1091)
                     /locus_tag="VCR92_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysin"
                     /protein_id="HEP4268947.1"
                     /translation="MATYQEYKSRSNGNAYDIDGSLGAQCWDGYADYCKYLGLPYANC
                     TNTGYARDIWEQRHKNGILNYFDEVETMQAGDVAIFMVVAGVTPYSHAAIFDSDAGSG
                     YGWFLGQNQGGANGAYNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGLNKGDYFIDVS
                     AYQQADLTATCQQAGTTKTIIKVSESLAWLSDRHQQQANTSDPIGYYHFGRFGGDSNL
                     AQREADLFLSNLPTKKVSYLVIDYEDSASADKEANTNAVIAFMDKIANAGYKPVYYSY
                     KPFTLNNIDYQQIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAG
                     GLDKNIVLLADDSSKVDIPKIDKPQSQLT"
BASE COUNT          358 a          265 c          209 g          403 t
ORIGIN      
        1 aaagtaagct ggctttgtgg tttgtcaatc ttaggtatat ccactttgct actatcatct
       61 gctaataata caatattttt atctaaacca cctgctactc ctacacttgt gaactgccac
      121 cagcgcacac catccattga agggaagaac tcccaaagtg gctctgttcg tacttcgtag
      181 tctggataac cagctatcca aatgctgttt gggtacttag cgataatttg ctgataatca
      241 atattattaa gcgtaaatgg tttatagctg taataaacag gcttatatcc agcgtttgca
      301 attttatcca taaacgcaat aactgcatta gtgttagctt ctttgtcggc acttgcagag
      361 tcttcataat caatgactaa gtaagagact tttttggttg gtaaattgga cagaaataaa
      421 tctgcttctc gttgcgctaa gttgctatct cctccaaatc gtccaaagtg ataataacca
      481 atagggtcac tagtattagc ttgttgctga tgcctatcag acagccaagc gagtgactcg
      541 gatactttga taatcgtttt agtagtgcca gcttgctgac aagtagcggt taagtctgct
      601 tgttgataag ctgatacatc aataaaataa tcgcctttat ttagtcctat attacctata
      661 acagtaactg catttttaaa aacttttggt ctaaatgcag taggataagt cgttgaatat
      721 ggtattttta ctaaattata tgctccgttt gctccaccct ggttttgacc taaaaaccat
      781 ccgtatccac tacctgcatc actatcaaaa atagccgcat ggctatacgg tgtaacacct
      841 gcaactacca taaaaattgc gacatctcca gcttgcatag tctctacttc gtcaaagtag
      901 tttaaaatac catttttgtg acgttgttcc catatatccc ttgcatatcc tgtatttgta
      961 cagtttgcgt atggcagtcc tagatactta cagtagtctg cgtagccatc ccaacattgc
     1021 gcaccaagcg atccatcaat atcgtaagca ttgccatttg aacgactttt atattcctga
     1081 tatgtagcca tttatccctc cttatctaaa aatggataaa aaatcaaagc aaccacagat
     1141 aatggcacat acagtattgc gattgctata actaatgcta atcgtgtgat tgctcgcatg
     1201 acctattcct cttccttgat ttgtgacaca ttcat
//
LOCUS       DATWEK010000116         1214 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.116, whole genome shotgun sequence.
ACCESSION   DATWEK010000116 DATWEK010000000
VERSION     DATWEK010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1214
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.116"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            113..>1214
                     /locus_tag="VCR92_001921"
     CDS             113..>1214
                     /locus_tag="VCR92_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEP4268948.1"
                     /translation="MKIVQGVQLHLIKTKQFKTNHITFRFSGDLNQKTVAKRVLVAQM
                     LATANECYPTVRQFREKLARLYGASLSTNVLTKGLVHIVDIDITFIQDRYACNGEKIL
                     DEMIQFLKDILFSPLLSIAQYQPKVFETEKNNLINYIESDREDSFYYSSLKVKELFYC
                     NKNLQMSEYGSPELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRVVQLIHQFPL
                     DNRNKNLNFFHLQNSVNIIKESIEKRAVHQSILQLAYHFPSVFGQRDYYALVLLNGLL
                     GSFAHSRLFIKIREEEGLAYSIGCRFDSYTGLFEIYTGIDSQHRTKTLQLIIQELNAI
                     KMGRFSEQLIKKTRSMLLNNALLSEDYNKNIIE"
BASE COUNT          440 a          187 c          191 g          396 t
ORIGIN      
        1 tattttacta acactagaat cccgacaatt aagtcaaaaa aagttatcac tcacctaacc
       61 tgaataaaaa tggtataatc gtaaggatca cactatttat taaggaaaca ttatgaaaat
      121 tgttcaggga gtacaacttc atctgattaa gaccaaacag tttaaaacca atcatattac
      181 ctttcgtttt tcaggtgatt tgaaccaaaa aacagtagca aaaagagtct tagtggcaca
      241 gatgttagca acagctaatg agtgttatcc aactgttagg cagtttagag aaaaattagc
      301 acgactttat ggagctagct tgtcaactaa cgtgttaaca aaagggttag ttcatattgt
      361 ggatatcgat attactttta ttcaagatag atatgcttgc aatggggaaa aaatactaga
      421 tgaaatgatt cagtttttaa aagatatctt gttctcaccc ctattatcca tcgcccagta
      481 tcagcctaaa gtttttgaga ctgaaaaaaa taatttgatt aactacatcg agtcagatag
      541 agaggattct ttttactaca gctctcttaa ggtaaaagaa ttgttttatt gtaataagaa
      601 tctacaaatg tcagaatatg gtagcccaga actaattgca aaagagactg cctatactag
      661 ctatcaagaa tttcataaaa tgctcaatga agatcagatt gatattttca ttttaggaga
      721 ttttgatgat tatcgcgttg ttcagctaat tcatcaattt ccacttgata accgaaataa
      781 aaacctaaat ttctttcatt tacaaaattc tgtcaatatt attaaagaat ctattgaaaa
      841 aagagcagtt catcaatcta ttttacaatt agcttatcac ttcccttcag tttttggaca
      901 acgtgactat tatgctttag ttcttttaaa tgggttgtta ggctcttttg cacattcccg
      961 tctctttata aaaattagag aagaagaagg acttgcttat agtatagggt gtcgttttga
     1021 tagttataca ggtttatttg aaatttatac tggaattgac agtcaacatc gcactaaaac
     1081 gttacaacta atcatccaag aattaaatgc cattaaaatg ggacgattct cagaacaatt
     1141 gattaaaaag accagatcga tgttgttgaa taacgcctta ttatcagaag attataataa
     1201 aaatataatt gaaa
//
LOCUS       DATWEK010000117         1133 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.117, whole genome shotgun sequence.
ACCESSION   DATWEK010000117 DATWEK010000000
VERSION     DATWEK010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1133
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.117"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..>1133)
                     /locus_tag="VCR92_001922"
     CDS             complement(<1..>1133)
                     /locus_tag="VCR92_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic dehydratase"
                     /protein_id="HEP4268949.1"
                     /translation="DKCNEKKKQNVKVSLNSYSKRAAFRTTPFGIFTAINTVDLTKGT
                     TSNVQKVSFIKKAVPDYSWIYSLVKSYEISNLEKLSLKINTAAFTQGDRYVLPFTVNE
                     SEEDRNISFSKPIKLLVEKCKTRYIKYEELIDVFKNNYPDIVSDMLESYIHDLVTNDF
                     LISDLRPPICNINSLDYLLSKLEEGTLCTDLTTLKKMIEDYNDLNIGEGRDLLLQIFD
                     KMESIYKYDNGGNYLKVDSLAEYEGGFNILSETARESIERLAEMFVKLNTNVKRRGGR
                     KNSLEEYQLKFIGKYGENCSIPFVEVINKDAGIGFPEYYKGGEGEAIELSDPIMQMFE
                     KKYEEALLNGGHIEFYSKDLDDFQTDQSNSLDSFELNFNIKII"
BASE COUNT          346 a          202 c          126 g          459 t
ORIGIN      
        1 tttattattt ttatattaaa atttaattca aacgaatcta aactattgct ttgatctgtt
       61 tgaaaatcat ctaaatcttt tgaataaaat tcgatatgcc ctccatttaa tagagcttcc
      121 tcatatttct tttcaaacat ttgcattatt ggatcgctta actctattgc ttcaccttct
      181 cctcctttgt aatattcagg aaaacctatg cctgcatctt tatttattac ttcaacaaaa
      241 ggaattgagc agttttctcc atatttgcca ataaatttca actgatactc ttcaagtgaa
      301 tttttcctcc cccctcttct ctttacattt gtatttaatt ttacaaacat ctctgcgagt
      361 cgttctatac tttcccgagc cgtttcagat agaatattaa aaccgccttc atactctgct
      421 aatgaatcaa cttttaagta atttccaccg ttatcatatt tataaatact ttccatttta
      481 tcaaaaatct gcaaaagtaa gtctctacct tccccaatat ttaaatcgtt gtaatcttca
      541 atcatcttct ttaaagtagt taagtcagta catagtgttc cttcttctaa tttagatagt
      601 agataatcta aggaattgat attacaaatt ggtggtctta aatctgaaat taaaaaatca
      661 tttgtaacta agtcgtgtat atatgactct agcatgtctg acactatatc tggataatta
      721 tttttaaata catctattaa ctcttcatat tttatatatc gagttttaca tttttctaca
      781 agtaacttaa ttggttttga aaaacttatg tttctatctt cctctgattc attcactgta
      841 aatggtagta catatctgtc accttgagta aacgccgctg tatttatttt taatgaaagt
      901 ttttcaaggt tacttatttc atacgatttt actagagaat atatccatga ataatctggg
      961 actgcttttt taataaaact aaccttttgt acattagaag tggttccctt tgtcaaatca
     1021 actgtattaa tagcagtaaa gataccaaat ggagtagttc taaacgctgc tcttttagaa
     1081 taactattta atgagacttt tacattttgc tttttctttt cattacattt atc
//
LOCUS       DATWEK010000118         1132 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.118, whole genome shotgun sequence.
ACCESSION   DATWEK010000118 DATWEK010000000
VERSION     DATWEK010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1132
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.118"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            97..531
                     /locus_tag="VCR92_001923"
     CDS             97..531
                     /locus_tag="VCR92_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP4268950.1"
                     /translation="MIDVSKKLKQLRIDRGIAKSRLITYLSITLRTYDRYEDGSRTPD
                     LVTLMKLSDFYQCSLDELVKGNTNDTLVDRALIVSYRDLKDKGLNDKLAHGLVKQVYD
                     TYEFEKIPQISDANRIKFIYKEDLVTLLESIVSKIQEEKKCD"
     gene            689..1129
                     /locus_tag="VCR92_001924"
     CDS             689..1129
                     /locus_tag="VCR92_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEP4268951.1"
                     /translation="MEHRLSMHYFQVKKEIFGVLLLSPVILLIMWGYVSSNQDDGRLT
                     QKQYYETVVNQTVNLVFYKKSCPYCKVAKKEIATQAKDSQVITYYVDTSTGEGQKLVK
                     KYHVKYAPTIVSIRKGNIQSFLYARDRGNNIIVEKEKIKEVFSQ"
BASE COUNT          415 a          124 c          229 g          364 t
ORIGIN      
        1 ttctctaagc tatatttttt tatttttgga aagggtatta agcatagtat cttttttaaa
       61 ggtaaaaatt tagaatgatt gaaagggagc tgaataatga ttgatgtatc aaaaaaacta
      121 aaacaactaa gaattgatag agggattgct aaatcgcggt tgatcactta tttatcgata
      181 actttaagaa cttatgacag atatgaagat ggtagtcgta ctcctgattt agtaacgtta
      241 atgaaattat cggattttta tcaatgctcg cttgatgaat tagttaaagg gaacacaaat
      301 gatacgcttg ttgatagggc attgattgtt tcgtatagag atcttaaaga taagggttta
      361 aatgataaat tggctcatgg tctagtgaag caggtctatg atacttatga atttgagaag
      421 attcctcaaa tatctgatgc taatagaatt aagtttatct ataaagaaga tttggttact
      481 ttacttgaaa gtatcgtgtc aaaaatacaa gaggagaaga aatgtgacta gctaaaagat
      541 tttggaggta atgaatgtta gtttatgaat ttattaaaca aaagattttg tgtcatcagc
      601 taaccaggtt gttacgaata ggtactgtaa tgataactgg actctcctat agtttagata
      661 actggaaaaa gtggaggggg attgaaatat ggagcatcga ttgagtatgc actattttca
      721 agtgaaaaaa gaaatttttg gggtattatt attgagtccc gttattttat tgattatgtg
      781 gggctatgtt tctagcaatc aagatgatgg tcgactaacg caaaagcaat actatgaaac
      841 agtggtcaac caaacggtta atttagtgtt ttataaaaag tcatgtccct attgcaaagt
      901 agctaaaaaa gaaattgcta ctcaagctaa ggatagtcaa gttattactt attatgttga
      961 tactagtacg ggagaaggac aaaaattggt taaaaaatac catgttaagt acgcacctac
     1021 aatagtatca attagaaaag gaaatattca atcatttttg tatgctcgag atagaggcaa
     1081 caacattata gtagaaaaag aaaagataaa agaagtattt agtcagtaag ct
//
LOCUS       DATWEK010000119         1128 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.119, whole genome shotgun sequence.
ACCESSION   DATWEK010000119 DATWEK010000000
VERSION     DATWEK010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1128
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.119"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            201..890
                     /locus_tag="VCR92_001925"
     CDS             201..890
                     /locus_tag="VCR92_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HEP4268952.1"
                     /translation="MLKIQNLKKSYGKRTILNNVNMNIPKGKVYALIGPNGAGKSTIM
                     KILTGLVSKTSGSIIFEGREWSRRDLRKIGSIIEEPPLYKNLSAYDNMKVVTTMLGVS
                     ESAILPLLNKVGLGNIDKRPVKQFSLGMKQRLGIAISLINSPKLLILDEPTNGLDPIG
                     IQELREIIESFKSEGMTIMISSHILSEVEHLADFIGFIYEGKIVLEKEYDGSENLEEL
                     FNNQILFEKRR"
     gene            896..>1128
                     /locus_tag="VCR92_001926"
     CDS             896..>1128
                     /locus_tag="VCR92_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HEP4268953.1"
                     /translation="MVQIFLSNLFKIKNTSISKLILIFPIICVMLSLLFSALGGESIL
                     RLAAETTVNQWGVIWINVIIAVNSGLLNKLELDS"
BASE COUNT          403 a          129 c          216 g          380 t
ORIGIN      
        1 ctcatgtctt atatgaaaga gtataatcga tttggtggta caaatgatat ctataatact
       61 aaattcaatt tagtaggaag ttttttacat ctatcaatga atcgattaaa cgggattgat
      121 agagagtttg aagagaaagt gtattgtttt gcttactata cactaaacgc tcagcaatat
      181 atagaatggg agtaactaat atgttgaaaa tacaaaatct aaaaaaatct tatggtaaga
      241 gaaccatatt gaataatgtc aatatgaata ttcctaaggg aaaagtgtat gctttaatcg
      301 gtccaaatgg tgctggaaaa tcaactatta tgaaaatttt gacaggctta gttagtaaga
      361 caagtggttc tattattttt gaaggtagag aatggtcacg tcgggatctg cgaaaaatcg
      421 ggagtattat tgaagaacca ccactttata aaaatttgag tgcttacgat aatatgaagg
      481 tagttacaac aatgcttggt gtttcagaaa gcgctatact tccattatta aataaagttg
      541 gtctaggaaa tattgacaag agaccagtaa aacaattttc tcttggaatg aagcaacggt
      601 taggtatagc tatctcttta ataaattcac ctaaattact tatattagac gaacctacta
      661 atggcttgga cccaattgga attcaagaat taagggaaat tatagagtca tttaaatcag
      721 aaggaatgac aattatgatt tcaagccata tactgtcaga agttgaacat ctagctgatt
      781 ttattggatt tatctatgaa ggaaagattg ttctggaaaa agaatatgac ggctctgaga
      841 atcttgaaga gttattcaat aatcaaattt tatttgaaaa gaggaggtag gggctatggt
      901 acaaattttt ttatcaaatt tatttaaaat aaaaaatacg agtattagca agttgattct
      961 tatttttcct attatttgtg tgatgttatc tttattgttt tcagcattag gtggtgaaag
     1021 tatcctacgt ttagctgcgg aaacaacagt aaatcagtgg ggagttattt ggattaatgt
     1081 tattattgct gtaaattctg gtttgttaaa taaattagaa ttagattc
//
LOCUS       DATWEK010000120         1016 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.120, whole genome shotgun sequence.
ACCESSION   DATWEK010000120 DATWEK010000000
VERSION     DATWEK010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1016
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.120"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..>1016)
                     /locus_tag="VCR92_001927"
     CDS             complement(<1..>1016)
                     /locus_tag="VCR92_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEP4268954.1"
                     /translation="IEQLKHDLAGVFNVDKPVKITYADEPDKYYLGLPVDDISHDNIT
                     RWFQRSEITILIPDGVAHSVTDARFEEPTWNGNKMTFKINNEGNVDAYPIITIKHNSE
                     NGYVGLVSQNGAFELGSKEEADSEEYKKSEILFDYTSNTGPTRILNGFEEGKFNEAIS
                     NVQEVLDGQLEVDNAWGRPHIHLKNGTSASITWDIPADSAGEVGALYEYIWWRQIFWA
                     GHQSQYGFMKVVVSDENGQFLYGTETFKRSNSLTTEYNFMVSDGKGGYHFLDRYTFWC
                     THLDSQNPFNEPRGWSDIYRKDGWIQFFWNGQYKEYNIPEIKGKKSAKVSVIFGSVGG
                     KPGVT"
BASE COUNT          273 a          240 c          169 g          334 t
ORIGIN      
        1 gtcactccag gtttgccccc tacgctccca aatataacac tgactttagc ggacttttta
       61 ccctttatct cagggatgtt gtattctttg tattgaccgt tccaaaaaaa ctgtatccag
      121 ccatctttcc tgtagatatc tgaccaacct cgtggctcat taaatggatt ttgactgtct
      181 aaatgcgtac accaaaatgt atagcggtca agaaaatgat agccaccttt tccgtcagaa
      241 accataaaat tatattcagt tgttagactg ttagaacgtt taaatgtctc tgtcccgtat
      301 agaaattgac cattttcatc tgatacaacc actttcataa atccgtactg cgattgatgt
      361 ccagcccaaa aaatctgtct ccaccagatg tactcatata gcgctcctac ctctcctgcg
      421 ctgtctgctg gtatgtccca agtgatagac gcagacgtcc catttttcaa gtggatgtgt
      481 ggtctccccc aagcattgtc tacctcaagt tgtccatcta gaacctcttg aacgttacta
      541 attgcctcat taaatttacc ctcttcaaat ccgtttaaaa tccttgttgg tccagtgttt
      601 gacgtgtaat caaacaagat ttcagatttc ttgtattctt cagagtctgc ttcttccttg
      661 cttccaagct caaaagcgcc attttgacta actagtccta catagccgtt ttctgaatta
      721 tgtttaatcg tgataatcgg ataagcatct acattcccct cattattgat tttgaacgtc
      781 attttattgc cgttccaggt aggctcttca aaacgtgcat ccgtcaccga atgagccact
      841 ccgtcaggga ttaaaatagt gatttctgaa cgctgaaacc aacgtgttat gttatcgtga
      901 gaaatatcgt caacaggcaa acctaaataa tacttgtctg gttcatctgc atatgtaatt
      961 ttgactggtt tatcaacgtt gaatacgcca gctaaatcat gtttaagctg ttcaat
//
LOCUS       DATWEK010000121          978 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.121, whole genome shotgun sequence.
ACCESSION   DATWEK010000121 DATWEK010000000
VERSION     DATWEK010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..978
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.121"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            126..407
                     /locus_tag="VCR92_001928"
     CDS             126..407
                     /locus_tag="VCR92_001928"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEP4268955.1"
                     /translation="MTVLNYVNAGDAKSIHNHLFHYTRQVRRHVKVITIGILSAHYYE
                     ITMLFLQAKIILDCFHIPQRLRQAITRFRIRIINTSAIKPIAYRTLKLY"
     gene            complement(884..971)
                     /locus_tag="VCR92_001929"
     tRNA            complement(884..971)
                     /locus_tag="VCR92_001929"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(935..937),aa:Ser,seq:gct)
BASE COUNT          338 a          206 c          115 g          319 t
ORIGIN      
        1 agaatgaatt tttagttact tatccacagg ttaataactt cttttcgcct aaaatattat
       61 ccacaatagt gacattttct attatcagtt atagtataat ttcattagga atctaaaacc
      121 ttagcatcac ggttttaaat tatgtaaatg ctggggacgc aaaaagcatt cataatcatc
      181 tctttcatta taccagacag gtgagaaggc atgtcaaagt tattaccata ggcatactca
      241 gtgcccacta ctatgagatt actatgcttt ttctacaggc taaaattatc ctcgattgtt
      301 ttcatatccc ccaacgtctt agacaagcta taactcgctt tcgtatccga atcataaata
      361 cttctgctat aaaacctatc gcgtatagaa ctctcaaact ttactgaaaa ctcatacagc
      421 atgattcacg gaagctcatc aataatagct ttattgccca atttttcgta cgcccataac
      481 taacatctag aaaagaaaag ctcttactca caagatctct gaatttcaat aattattcct
      541 aactctatca actcttgctc ttcccatttt tcagacaatt tttaaaattt ttctaaaaga
      601 aaagaaaaca agattagcaa tatacttaaa ctcaactact ctaaggccaa attagaaaca
      661 gtcaacaacc ttatcaaagc catcaagtta aacgttttac tcctctacag tagtcaaaga
      721 gcctatcatt ttagttatcg aaataatgaa cgatttaaat attctattta gttggttttg
      781 aagattacaa aaaaaagacg ataaccgtct tctttccccc ttatttataa ttcatccttt
      841 aatatgtttc atttaacata ttaaccaaaa tatctttaca aaacggagaa taagggattc
      901 gaacccttgc gccagttacc cgacctaacg atttagcaaa ccgtcctctt cagcctcttg
      961 agtaattctc caaatata
//
LOCUS       DATWEK010000122          962 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.122, whole genome shotgun sequence.
ACCESSION   DATWEK010000122 DATWEK010000000
VERSION     DATWEK010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..962
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.122"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..>962
                     /locus_tag="VCR92_001930"
     CDS             <1..>962
                     /locus_tag="VCR92_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEP4268956.1"
                     /translation="RKRNEQAGQTTNQTNQAAQAAYQEKLAEIERINAENAAIRDRNT
                     KARQEAERQNQQLKTTYEAQLSAYQQALQAKKEAENKAIDQVVFGIDAKANGVDNAEY
                     GNSIMTVTTQPDGSFVFKHDMIDGVKTIGHGTLTGKINHHYEANKDGSITAYIDSVTF
                     DKYEYQNVAKNDAVDKNIAFRILSATGQELFVKAHDGDKTFSETLNKTVSLKLTYQLK
                     PHEAVKDIKVFQLHDDWVHDTHGSALVSYVNNNDAVPHIEVPEKPVEPDMVTPKVEQE
                     KPVPEAPQKPTDGVPNLEKEKPVPPTPVKPEAVKPVLEQEKPVP"
BASE COUNT          357 a          178 c          189 g          238 t
ORIGIN      
        1 cgtaagcgta atgaacaagc aggtcaaacg acgaatcaaa cgaatcaagc ggctcaagct
       61 gcctatcaag aaaagctagc agagattgag cgtattaacg ccgagaatgc cgccattcgt
      121 gatcgcaaca ctaaagctcg acaagaagca gaacgtcaaa accaacagtt aaaaactact
      181 tatgaagctc aattatcagc ctaccaacaa gcactacaag ctaaaaaaga agctgaaaac
      241 aaagctatcg atcaggttgt ctttggaatt gatgcaaaag ccaacggtgt tgataatgca
      301 gaatatggta attcaatcat gactgttaca acgcaaccag atggttcgtt tgtttttaag
      361 catgatatga ttgatggtgt caaaacaatt ggtcatggga ctttaacggg taaaattaat
      421 catcattatg aggctaataa agatggtagc attacagctt atattgatag tgtaacattt
      481 gataagtatg aatatcaaaa tgtagctaaa aatgacgcag ttgataaaaa tattgctttt
      541 cgtattttaa gtgccacagg tcaagaatta tttgttaaag cccatgatgg tgataaaact
      601 tttagtgaaa ctttaaataa gacagtgtct cttaagttaa cttaccaact aaaaccgcat
      661 gaagctgtaa aagatatcaa agtatttcaa ctgcatgatg actgggtaca cgacacacat
      721 ggttctgctt tagtttctta tgtgaacaac aatgatgctg tgccacatat tgaagtacca
      781 gaaaagccag tggagcctga tatggttaca ccaaaagttg agcaagaaaa accagtccca
      841 gaggctcctc aaaaaccaac agatggtgtt ccaaacttag agaaggaaaa gccggttcct
      901 ccaaccccag ttaaaccaga ggcagttaaa cctgttttag aacaagaaaa accagtacca
      961 ga
//
LOCUS       DATWEK010000123          947 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.123, whole genome shotgun sequence.
ACCESSION   DATWEK010000123 DATWEK010000000
VERSION     DATWEK010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..947
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.123"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..252
                     /locus_tag="VCR92_001931"
     CDS             <1..252
                     /locus_tag="VCR92_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEP4268957.1"
                     /translation="VYRKDFVTGTRDIPNRYAMGSTVVIDNETNTVTKDGLNKNSDIV
                     QGSHHFLSVPPGESELDIYFSSWIKKMPTVKVEFENRSL"
     gene            253..>947
                     /locus_tag="VCR92_001932"
     CDS             253..>947
                     /locus_tag="VCR92_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEP4268958.1"
                     /translation="MILTIHDAQLRKVAFVDNEKQGTLDFFDDTWTRNLQTGSSTYEF
                     SISKKSLVSDMVFNRTYSYLNERAFVSFEYKGETFLFNVMTVEEDEKKIKCYCENLNL
                     ELINEYSNPFKAGRAMSFVEYCNAMDLLNMTKLSVGINEISDYKRTLEWEGQDTKLAR
                     LISLANKFDAEIEFKTYLNDDSTIKQFLVNVYHENDGVNYHGVGRDRKDITLVYGKNI
                     KSIRRKIDKTNIF"
BASE COUNT          314 a          163 c          201 g          269 t
ORIGIN      
        1 gtttatcgca aagattttgt gacaggtact agagacatcc cgaaccgcta tgctatgggc
       61 tcaacagttg tcatcgacaa cgaaacaaac acagtgacta aagacggtct taacaaaaat
      121 tcggacatcg tccaaggctc acatcatttc ttgagtgttc cgcctgggga gtctgagttg
      181 gacatctatt tctcatcgtg gattaaaaaa atgcctacag ttaaggtgga gtttgagaat
      241 aggagtttgt aaatgattct aacaatacac gatgcacaac tgagaaaagt agcgttcgtt
      301 gataatgaga agcaaggcac gttagatttt ttcgatgaca cttggacacg caatttgcaa
      361 actgggtcat caacatatga atttagcatt tcaaaaaaat cacttgtttc tgacatggtc
      421 tttaacagaa cttacagcta tttgaatgaa cgtgcttttg tttcatttga gtacaaaggc
      481 gagacgtttc tctttaacgt gatgactgtt gaagaagatg aaaagaaaat caaatgctat
      541 tgtgagaatt taaatctaga acttattaac gagtattcga atccgtttaa ggctggtaga
      601 gctatgtcat tcgttgagta ttgcaatgct atggatttac taaatatgac taaattatcc
      661 gtaggtatca acgagatttc ggactacaag cgtacgttgg aatgggaagg acaagacacg
      721 aaacttgcca gacttatttc acttgcgaac aaatttgatg ctgaaatcga atttaaaacc
      781 tacctcaacg atgacagtac tatcaagcag tttttggtca atgtttatca cgaaaatgat
      841 ggcgtgaatt accacggcgt tgggcgtgac aggaaagaca taacgcttgt ttacggaaaa
      901 aacatcaagt caattaggcg caagattgat aagacgaaca tctttaa
//
LOCUS       DATWEK010000124          947 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.124, whole genome shotgun sequence.
ACCESSION   DATWEK010000124 DATWEK010000000
VERSION     DATWEK010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..947
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.124"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..695)
                     /locus_tag="VCR92_001933"
     CDS             complement(<1..695)
                     /locus_tag="VCR92_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEP4268959.1"
                     /translation="MLLTIHDAHLKKVAFIDNEKQGTLSFYDDTWTRNLQTGSSTYEF
                     SISKKTLVSDTVLNRTYSYLNERAFVSFEYKGETFLFNVMTVEEDEKKIKCYCENLNL
                     ELINEYSNPFKADRAMSFVEYCNAMDLLNMTKLSIGINEISDYKRTLEWEGQDTKLAR
                     LISLANKFDAEIEFKTYLNDDSTIKQFLVNVYHENDGVNYHGVGRDRKDITLVYGKNL
                     KSIKRKVDKTNIF"
     gene            complement(696..>947)
                     /locus_tag="VCR92_001934"
     CDS             complement(696..>947)
                     /locus_tag="VCR92_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEP4268960.1"
                     /translation="VYRKDFVTGTRDIPNRYAMGSTVVINNETDTVMKDNLNKNEDIV
                     QGSHHFLSVPPGESELDIYFSSWIKKMPTVKVEFEKRSL"
BASE COUNT          269 a          198 c          158 g          322 t
ORIGIN      
        1 ttaaagatat ttgtcttgtc aaccttgcgc ttgattgact taagattctt cccataaacc
       61 agcgtaatgt cttttctgtc acgcccaacg ccgtgataat taacgccgtc attttcgtga
      121 taaacattga ccaaaaactg cttgatagta ctgtcatcgt tgagatatgt tttaaattcg
      181 atttcagcat caaatttgtt cgcaagtgaa ataagtctgg caagtttggt gtcttgccct
      241 tcccattcca aagtgcgctt gtaatctgaa atctcattaa taccgatgga taatttagtc
      301 atatttagta aatccatagc attacagtac tcaacaaatg acatagctct gtctgcttta
      361 aacggatttg aatattcgtt aataagttct aggtttaaat tctcacaata acatttgatt
      421 ttcttttcat cttcttcaac agtcatcaca ttaaacagaa acgtctcgcc tttatattca
      481 aacgacacaa aggcacgttc gttcaaatag ctgtatgttc tgtttaagac tgtatctgaa
      541 acaagcgtct tcttagagat gctaaactca tacgttgacg aacctgtttg tagattacgt
      601 gtccaagtat cgtcgtaaaa actcaatgtg ccttgcttct cgttgtcaat aaacgctact
      661 ttcttcaaat gtgcatcgtg tattgttaga agcatctaca agctcctttt ctcaaactcc
      721 actttgactg taggcatttt cttgatccat gatgagaaat agatgtctaa ctcagactcg
      781 ccaggcggaa cactcaagaa atgatgtgag ccctgtacga tatcctcatt tttattcaag
      841 ttatctttca tcactgtgtc tgtttcgttg ttaataacaa cggttgagcc catagcatag
      901 cggttcggga tgtctctagt acctgtcaca aaatctttgc gataaac
//
LOCUS       DATWEK010000125          901 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.125, whole genome shotgun sequence.
ACCESSION   DATWEK010000125 DATWEK010000000
VERSION     DATWEK010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..901
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.125"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..176)
                     /locus_tag="VCR92_001935"
     CDS             complement(<1..176)
                     /locus_tag="VCR92_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015968624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEP4268961.1"
                     /translation="MTEIMTFNGIGMSQYFRITDIIRPIGNKRTVSTDTSPFLGVNIQ
                     EIKIGAKEHKIKFD"
     gene            complement(173..865)
                     /locus_tag="VCR92_001936"
     CDS             complement(173..865)
                     /locus_tag="VCR92_001936"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268962.1"
                     /translation="MKNQGRMIGQQTAQNIAQGISSGAGSARSAMSSLMASVRAAGMS
                     GVGSMRAIGAYIGQGLASGMMSALGSVTAAANALVAQAERAARAKAKIHSPSRLFRDN
                     VGRYIAQGVAVGIEKDSYTVNDALGAMYDKVQAFSYRAEDLIGAGSTNFSHSIQVKSD
                     LDKAIKAKVEIVQEKSNEVMEKAIDAMGKLADRPIDMRLNDDTLIASTSDRYQDYQQT
                     QITRNNRMWGRP"
BASE COUNT          227 a          207 c          167 g          300 t
ORIGIN      
        1 atgtcaaatt tgattttgtg ttctttagct ccgattttaa tttcttggat attaacaccc
       61 aaaaaaggag aagtgtcagt tgacactgtc cttttattac caatcgggcg aataatgtca
      121 gtaatcctaa agtattgaga catcccaata ccgttaaatg tcattatttc tgtcatggtc
      181 taccccacat tctgttgtta cgtgtaattt gtgtttgttg ataatcttgg tatctgtcac
      241 tagttgatgc gataagcgtg tcatcgttca aacgcatgtc gattggacgg tctgcgagtt
      301 tacccatcgc atctatagct ttttccataa cttcgtttga tttttcttgt acgatttcaa
      361 cttttgcttt gattgcttta tctaaatcgg atttaacctg gatactgtgt gagaaattag
      421 ttgatccagc tccgattagg tcttcagctc tgtagctaaa tgcttgtact ttgtcataca
      481 ttgcacctaa agcatcgtta actgtgtagc tgtccttttc aataccaacc gcaacacctt
      541 gtgcaatata gcgacctaca ttgtcacgga ataggcgcga tggtgaatga attttggctt
      601 ttgctcgtgc cgctctctct gcttgtgcta ctaacgcatt agcagctgcc gtcacacttc
      661 caagagctga catcatacca ctagccaaac cttgcccgat atatgcacca attgcacgca
      721 ttgaaccgac tccagacatc cctgctgcac gtacagatgc cataagagaa ctcattgccg
      781 accttgcact accagcaccg ctagaaatac cttgagcgat attttgagct gtttgttgac
      841 caatcatgcg tccttgattt ttcatctgat ttccaataga tgtaacagca ctaagcattg
      901 c
//
LOCUS       DATWEK010000126          819 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.126, whole genome shotgun sequence.
ACCESSION   DATWEK010000126 DATWEK010000000
VERSION     DATWEK010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..819
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.126"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            19..705
                     /locus_tag="VCR92_001937"
     CDS             19..705
                     /locus_tag="VCR92_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP4268963.1"
                     /translation="MYKILAIDDDKEILKLMKTALEIENYHVITCQEIELPIVFDDFK
                     GYDLILLDIMMPNISGTEFCYKIREEVHSPIIFVSALDGDNEIVQALNIGGDDFIVKP
                     FSLKQFVAKVNSHLKREERAKIKNEAEERVKRSFPPIEIYLEERMLYIDKQPLFLTYR
                     EYEILELLSRHPYKVFTKEEIYEQVYSDEASALFHSISEYIYQIRMKFSSFGINPIKT
                     IRGIGYKWDV"
BASE COUNT          286 a           96 c          160 g          277 t
ORIGIN      
        1 tatttaaaag gggtaataat gtataagatt ttagccatag atgatgataa agaaattctg
       61 aagcttatga agactgcttt ggagattgaa aattaccatg ttataacctg tcaagagata
      121 gaattaccaa tagtttttga tgattttaaa ggatatgatt tgatcttatt ggatatcatg
      181 atgcctaata taagtggaac tgagttttgt tataaaattc gggaagaagt tcattctcca
      241 attatttttg ttagcgcttt agatggcgat aatgaaattg tccaagcttt aaatataggg
      301 ggagacgatt ttattgtgaa accatttagc ttaaaacaat tcgtagctaa agttaactct
      361 catttgaaga gagaagagag agcaaagata aagaatgagg ctgaggagag agtgaagcgc
      421 agttttccac ctatagaaat ctatctagag gaacgtatgt tatatattga taaacagccg
      481 ttattcctga cttatagaga gtacgaaatt ttagaattac tgtcacgtca tccgtataaa
      541 gttttcacaa aagaagagat atatgaacaa gtatatagcg atgaagcttc agcattgttt
      601 cattctattt cagaatatat ctatcagatt agaatgaaat tttcaagttt tggaattaat
      661 ccaataaaaa ctattcgcgg gattggttat aaatgggatg tttaaaaaat attcaataaa
      721 aaatcgtgtt tggcgcgccg tcgttgaaat tgtctttgga gtttgtatca ctgttttaat
      781 gattgcgata atatcgcttt ctttttcaaa gttaaatat
//
LOCUS       DATWEK010000127          782 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.127, whole genome shotgun sequence.
ACCESSION   DATWEK010000127 DATWEK010000000
VERSION     DATWEK010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..782
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.127"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..>782
                     /locus_tag="VCR92_001938"
     CDS             <1..>782
                     /locus_tag="VCR92_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HEP4268964.1"
                     /translation="VGLSIGLLLAKEHDVTFFDIDNKKIDLINKRQSPLKEAAINKLL
                     CKAKNINATSSEELAYKDATFIILSLPTNLKFNKLDTSIIEISVSNILKINKKATIVI
                     KSTVPIGFTEYLRNRFHYNDIIFSPEFLREGSTIHDQLYPSRTIVGNESRNSQLFLDI
                     LTDISVEKDSPSLLVGSSEAEAIKLFSNAYLAQKIAFFNELDTFAEMQNLDSKKIIEA
                     MGYDQRIGNSHNNPSFGFGGYCLPKDIKQLEYHFKEIPAPII"
BASE COUNT          279 a          123 c          126 g          254 t
ORIGIN      
        1 acgttggatt atcgataggg ctcctacttg caaaggaaca cgacgtcacc ttttttgata
       61 ttgataataa aaaaattgat ttaataaata aaaggcaatc ccctcttaaa gaagcagcta
      121 taaacaaact tttatgtaag gcaaaaaata ttaatgcaac ttcttctgaa gaattagcat
      181 ataaggatgc gactttcata atcttgtctt tgccaaccaa cctaaaattt aataagcttg
      241 atacttccat tatcgaaatt tctgtaagta atattttaaa gataaacaaa aaggctacaa
      301 ttgtaataaa gtcgacagtt ccaattggtt ttacagaata tttaaggaat cgatttcact
      361 acaacgatat cattttttca cctgagttcc ttagggaagg atcaactatt catgatcaat
      421 tgtatccttc gagaactata gttggaaatg aatctagaaa ttctcaatta ttcttagaca
      481 tactaacaga tatatcggtt gaaaaagact cgccatcttt attagttggc tcttctgaag
      541 cagaagcgat aaagttattt tcgaatgcat acttggcaca aaaaattgct ttttttaatg
      601 agttggatac gtttgctgaa atgcaaaatt tggactcaaa aaaaattatt gaggctatgg
      661 gatatgacca gagaatagga aattcgcaca ataatccttc tttcggtttt ggtgggtact
      721 gtcttcctaa ggatattaag caattagagt atcattttaa agaaattcca gcaccaatta
      781 tt
//
LOCUS       DATWEK010000128          749 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.128, whole genome shotgun sequence.
ACCESSION   DATWEK010000128 DATWEK010000000
VERSION     DATWEK010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..749
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.128"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            49..>749
                     /gene="mf2"
                     /locus_tag="VCR92_001939"
     CDS             49..>749
                     /gene="mf2"
                     /locus_tag="VCR92_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNase Mf2"
                     /protein_id="HEP4268965.1"
                     /translation="MKLSKQKASLLTAVLLLLSLSITTITVDAAKVRTYPNVSHANTH
                     YKNTASSKLLPFTANYQLQLGELDNLNRATFSHIQLQDRHETKDVRTKINYDPVGWHN
                     YQFPYGDGSKSSWVMNRGHLVGYQFCGLNDEPRNLVTMTAWLNTGAYSGANDSNPEGM
                     LYYENRLDSWLALHPDFWLDYKVTPIYSGNEVVPRQIELQYVGIDSSGELLTIRLNSN
                     KESIDENGVTTVILE"
BASE COUNT          251 a          133 c          138 g          227 t
ORIGIN      
        1 tatttgatcc actctaaaag ctaaaaatgg aaaggtttag gtgttatcat gaaattatct
       61 aaacaaaagg caagtttgct taccgctgtt ttactgttac tttctctttc tataacgaca
      121 ataactgttg acgcagctaa ggtacgaact tatccgaatg tatcccatgc aaacacacat
      181 tataaaaata ctgcttctag taagctctta ccttttactg ctaattatca gttacaactt
      241 ggtgagttgg ataaccttaa ccgcgctacc ttttcacata tccaactgca agatagacac
      301 gaaactaaag atgtacgcac taaaataaat tatgaccctg tgggatggca taactatcaa
      361 tttccatacg gagatggctc aaaatcttca tgggtaatga atcgtgggca tctagtcgga
      421 tatcaatttt gtggattaaa cgatgaacca agaaatttag tgacaatgac agcctggcta
      481 aacacaggtg cttattcagg agcaaatgac agcaatcctg aagggatgtt atactatgaa
      541 aaccgtttag attcttggct tgcacttcac cctgactttt ggctagatta taaagtcact
      601 cctatatata gtggcaatga agtagtgcct cgacaaattg aattacagta tgttggaatt
      661 gattcatctg gtgagttgct tactataagg ctaaatagta ataaagaaag tattgatgaa
      721 aatggtgtta ctacagtaat cttagaaaa
//
LOCUS       DATWEK010000129          746 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.129, whole genome shotgun sequence.
ACCESSION   DATWEK010000129 DATWEK010000000
VERSION     DATWEK010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..746
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.129"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..647
                     /locus_tag="VCR92_001940"
     CDS             <1..647
                     /locus_tag="VCR92_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEP4268966.1"
                     /translation="REAEFDLGIAHGITGPMLILAKLKSEKILSVEVGDILNKAINLM
                     FLFRRDDKLWPGKIYTSNILDLDLNYLPTRMAWCYGTPGTAVALFKMCQLIDLNFIDD
                     INESLIAQMRSSDKNVYSLTMCHGLAGVTFIYDLIGKNYSSERLTRFAEELRQQIITS
                     FSTTKVFGYTDREKFGEIEVELESIGILQGVSGIVLFLLNPYSDEELLWQRIFI"
BASE COUNT          267 a           88 c          148 g          243 t
ORIGIN      
        1 atagagaagc tgaatttgat ctaggaattg cacatggaat tactggtcct atgctaatcc
       61 tagcaaaatt aaaatcagaa aaaattttga gtgtagaagt aggagatata ctgaataaag
      121 ctataaattt aatgttttta tttagaaggg atgacaaact atggcctgga aaaatttata
      181 ctagtaatat tttggatctt gatttaaatt atcttcctac tagaatggca tggtgttacg
      241 gtacgcctgg aactgcagtt gcccttttta aaatgtgtca attgatagat ttaaatttta
      301 ttgacgatat taatgaaagt ttaattgctc agatgagaag ttcagacaaa aatgtctatt
      361 ctcttacaat gtgccatggt ttggcaggag taacttttat atatgacttg attggtaaaa
      421 attattcaag tgagaggcta actcgctttg cagaagagct tcgccaacaa ataattacat
      481 cgttttcaac tacaaaagta tttgggtata ctgacagaga aaaatttgga gaaatagaag
      541 ttgaactgga gtcaataggg atattgcaag gggtatcagg gatagtgtta ttcttattaa
      601 atccttacag tgacgaggag ctattgtggc aaagaatatt tatttaattt gaaaaggaga
      661 acaaaatgta taaggtattt ccaactggta tgattcgtat tccattgcaa aaacaagaat
      721 tttataataa agactatgaa gattta
//
LOCUS       DATWEK010000130          720 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.130, whole genome shotgun sequence.
ACCESSION   DATWEK010000130 DATWEK010000000
VERSION     DATWEK010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.130"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(1..74)
                     /locus_tag="VCR92_001941"
     tRNA            complement(1..74)
                     /locus_tag="VCR92_001941"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(38..40),aa:Arg,seq:acg)
     gene            complement(91..175)
                     /locus_tag="VCR92_001942"
     tRNA            complement(91..175)
                     /locus_tag="VCR92_001942"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(139..141),aa:Leu,seq:taa)
     gene            complement(184..255)
                     /locus_tag="VCR92_001943"
     tRNA            complement(184..255)
                     /locus_tag="VCR92_001943"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(221..223),aa:Gly,seq:gcc)
     gene            complement(268..340)
                     /locus_tag="VCR92_001944"
     tRNA            complement(268..340)
                     /locus_tag="VCR92_001944"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(305..307),aa:Thr,seq:tgt)
     gene            complement(351..432)
                     /locus_tag="VCR92_001945"
     tRNA            complement(351..432)
                     /locus_tag="VCR92_001945"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(396..398),aa:Leu,seq:tag)
     gene            complement(438..510)
                     /locus_tag="VCR92_001946"
     tRNA            complement(438..510)
                     /locus_tag="VCR92_001946"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(475..477),aa:Lys,seq:ttt)
     gene            complement(542..614)
                     /locus_tag="VCR92_001947"
     tRNA            complement(542..614)
                     /locus_tag="VCR92_001947"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(579..581),aa:Asp,seq:gtc)
     gene            complement(632..704)
                     /locus_tag="VCR92_001948"
     tRNA            complement(632..704)
                     /locus_tag="VCR92_001948"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(669..671),aa:Val,seq:tac)
BASE COUNT          185 a          207 c          158 g          170 t
ORIGIN      
        1 tgcaccctag aggagtcgaa cctctaaccg cctgattcgt agtcaggtac tctatccagt
       61 tgagctaagg gtgctatttc aaaaaattaa tgccgaggac cggaatcgaa ccggtacgat
      121 gtaaaccatc gcaggatttt aagtcctgtg cgtctgccag ttccgccacc ccggctcctc
      181 aaaagcgaac gacgggattc gaacccgcga cccccacctt ggcaaggtga tgttctacca
      241 ctgaactacg ttcgcaacta atctcaatgc cggctacatg acttgaacac gcgaccctct
      301 gattacaaat cagatgctct accaactgag ctaagccggc taatctttta tgcgggttaa
      361 gggacttgaa cccccacgcc gttaagcgcc agatcctaaa tctggtgcgt ctgccaattc
      421 cgccaaaccc gcttttatga cccgtactgg gctcgaacca gtgacccatt gattaaaagt
      481 caattgctct accaactgag ctaacgagtc tttccttcaa aaaatatgac tactctttga
      541 acggtcccga cgggaatcga acccgcgatc ttcgccgtga cagggcgacg tgataaccgc
      601 tacactacgg gacctgtatt ttccaatact atgggagtta acgggatcga accgctgacc
      661 ctctgcttgt aaggcagatg ctctcccagc tgagctaaac tcccattgag tgtgtcatta
//
LOCUS       DATWEK010000131          713 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.131, whole genome shotgun sequence.
ACCESSION   DATWEK010000131 DATWEK010000000
VERSION     DATWEK010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..713
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.131"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..>713
                     /locus_tag="VCR92_001949"
     CDS             <1..>713
                     /locus_tag="VCR92_001949"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268967.1"
                     /translation="SEENSDQKLTIGSLPNWELKNDKGIVEFYKRGDALYAPISAQLY
                     PSTFTSETQSDQWTRRDMDFNVKSIQQLETEGLKQLKASAYPELTYEFDGYIDADIGD
                     TVELSDGGFANTLLIEARIFEQKLSFSTKKNWKTTLGNFRALQSKLSNDIQSELERLV
                     EDAKPYNIRISTDNGTMFKNNEGESLVKATLWKGGKVVSRDVSWRWALDGVVTVGMQY
                     RVQAKDITDTAVLTVSGYVG"
BASE COUNT          226 a          138 c          172 g          177 t
ORIGIN      
        1 agtgaagaga acagtgatca gaaattgact atcggaagct tgccaaactg ggagctcaag
       61 aatgataaag gcatcgttga gttttacaag cgtggcgatg ctctctatgc gcctatttca
      121 gcacagcttt atccgtcaac gtttacgtcg gaaactcaat cagatcaatg gactagacgt
      181 gacatggact ttaacgtcaa aagcattcaa cagcttgaga cagaaggttt gaaacagttg
      241 aaagcgtcag cttatccaga attaacatac gaatttgacg gctatattga tgcagatatt
      301 ggagacacag tagagctctc agatggtggc tttgctaaca cattgctgat tgaagcacgt
      361 atttttgaac aaaagctaag cttttcgact aaaaaaaact ggaagaccac acttggaaat
      421 tttagagctt tgcaaagcaa gttatctaac gacatccaga gcgaacttga acgtttagta
      481 gaagatgcaa aaccgtacaa tattcgcatt tcgacggata atggaacgat gttcaagaac
      541 aatgagggcg aaagtctagt aaaagccaca ctttggaaag gtggcaaagt tgttagtcgg
      601 gacgtctcat ggcgctgggc tttggacggc gtggtcacag tcggtatgca ataccgtgtc
      661 caagctaaag acatcactga cacagcggtt ttaaccgtct cgggctatgt cgg
//
LOCUS       DATWEK010000132          643 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.132, whole genome shotgun sequence.
ACCESSION   DATWEK010000132 DATWEK010000000
VERSION     DATWEK010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..643
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.132"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
BASE COUNT          207 a          130 c           80 g          226 t
ORIGIN      
        1 ttatttttta acaaaaaagt cgacttatga aagaagtcga catagaaaaa aatattctca
       61 ctatatttca atttaaattg catgctcgta tcttcgcaca ctcctttcac tatgtttctc
      121 aacatgagct actcagtcga ataagtccac cttatccttt agctagacaa agtctaacac
      181 accgcccaca ataccatacc taatccgcct caccacgttt tcagtaatca ttgtcaacac
      241 cccttgcaga gtagcagttt tagttttttg ctcaacacag gctaactaac ataaacctta
      301 gtgtgctttt gaggtctgaa ctttacttgt ttagttgaac acacagtaat tactataatc
      361 atggccacaa ctattttgca tcaattttta tagtaaaact aagctaggta ggaataacta
      421 tctaactttt tttgcttaaa caagcaaaat tcaaacttca aaagttatca gacaacttgg
      481 tatagtaaac tacacttgct ttacttctga agaatttcac gctataataa aagtgtctat
      541 gttttattat gtgtgttatt caacttagct tagctgtgtt gtctgacgca ctttttattt
      601 aattatcaat gttctaaaat ttaactctat tcctcaaatt agt
//
LOCUS       DATWEK010000133          641 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.133, whole genome shotgun sequence.
ACCESSION   DATWEK010000133 DATWEK010000000
VERSION     DATWEK010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..641
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.133"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(196..609)
                     /locus_tag="VCR92_001950"
     CDS             complement(196..609)
                     /locus_tag="VCR92_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEP4268968.1"
                     /translation="MKLNAIHHVAIIVSDYHLSKDFYVNKLGFEIIRENYRSDKHDYK
                     LDLSCGRIELEIFGKVTSDPNYQAPPKRVSQPEFKSEACGLRHLAFRVTNIESYVDDL
                     KSLGIPVEPIRHDDYTGEKMTFFFDPDGLPLELHE"
BASE COUNT          229 a          124 c           89 g          199 t
ORIGIN      
        1 tcgtcaaata ttttgctttt cctatagtta ttctattaaa aaacttcgac aagattactc
       61 caaaaattgc tcttcacttt gaaagttaac caaatcattt aacgatcaaa agagattaat
      121 caagcaaaag aagatacaac aaataactat ttttaacgag tttaatagca cgatccagtc
      181 gttaacctaa taagtctatt catgtaattc taaaggcaaa ccatccggat caaaaaagaa
      241 agtcattttc tcacctgtgt aatcatcatg cctaataggc tccactggaa ttcctaagct
      301 ctttagatca tctacataac tctcaatgtt ggtaacacga aaagcaaggt gcctcaaacc
      361 acaggcctca cttttaaatt ctggttgact tacacgttta ggaggagctt gatagttggg
      421 gtcacttgtc accttaccaa aaatctccaa ttcaatacga ccacaagata aatctaattt
      481 gtaatcatgc ttgtcagaac gataattttc tctgataatt tcaaatccga gtttattcac
      541 ataaaaatct tttgacagat gataatcaga tacaataata gcaacgtgat gaatggcatt
      601 tagtttcatc atatttctcc tttcaaaaaa agtaggatga g
//
LOCUS       DATWEK010000134          609 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.134, whole genome shotgun sequence.
ACCESSION   DATWEK010000134 DATWEK010000000
VERSION     DATWEK010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..609
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.134"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..171
                     /locus_tag="VCR92_001951"
     CDS             <1..171
                     /locus_tag="VCR92_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEP4268969.1"
                     /translation="KQMIKLLKKNGFYEVGQRGSHKKFRDDKGHQTIVPLHNKDLGKG
                     LEDAILKQAGLK"
     gene            229..606
                     /locus_tag="VCR92_001952"
     CDS             229..606
                     /locus_tag="VCR92_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEP4268970.1"
                     /translation="MLVYPALFTQDGDYILVTFPDIPEAITQGKDIQEAFEMATEVLG
                     FALEDYKEYPKPTSPSDLKEQFPDSYIALIQIDMLAYMKKYHANKVRKNVTIPEWLNE
                     LAEENNLNFSQVLTEALELKLQA"
BASE COUNT          225 a          106 c          111 g          167 t
ORIGIN      
        1 aagcagatga taaagttgct taaaaagaac gggttttacg aagtcggtca acgtggaagt
       61 cataagaagt tccgagacga taaaggacat caaacaattg tgccactgca caataaagac
      121 cttggtaaag gtcttgaaga tgctatttta aaacaagcag gtttaaaata atctgcttgc
      181 tgaatagcaa ttttatctca ctaaaacaat taaaaggaga attatcgtat gttagtttat
      241 ccagctttat tcactcaaga cggcgattat attcttgtaa cttttccaga catccctgag
      301 gctatcactc aaggaaaaga tatccaagaa gcttttgaaa tggctacaga ggttctaggg
      361 tttgcgcttg aagattacaa agaataccca aaaccaactt cgccatcaga tttgaaagag
      421 caatttcctg atagttatat tgcattgatt caaattgata tgctagcgta tatgaaaaaa
      481 tatcacgcaa acaaagttcg caaaaatgta actatcccag aatggttaaa cgaactcgca
      541 gaagagaata acctcaactt ttctcaagtt cttactgaag cgcttgaatt aaaattacaa
      601 gcataagag
//
LOCUS       DATWEK010000135          534 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.135, whole genome shotgun sequence.
ACCESSION   DATWEK010000135 DATWEK010000000
VERSION     DATWEK010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.135"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..>534
                     /locus_tag="VCR92_001953"
     CDS             <1..>534
                     /locus_tag="VCR92_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISAs1-like element IS1548 family transposase"
                     /protein_id="HEP4268971.1"
                     /translation="TDRLKELKVQFEQSLTSLDAVHQLISVDGKTIRGNRGKNQKPVH
                     IVTAYDGGHHLSLGQVAVEEKSNEIVAIPQLLRTIDIRKSIVTIDAMGTQTAIVDTII
                     KGKADYCLAVKGNQETLYDDIALYFSDVNLLEELQENAQYYQTVEKSRGQIEVREYWV
                     SSDIKWLCQNHPKWHKLR"
BASE COUNT          178 a           86 c          122 g          148 t
ORIGIN      
        1 tacagaccgt ttaaaagagc ttaaagttca atttgagcaa tcattgacaa gcttagatgc
       61 cgttcatcaa ctgatttcag tggacggtaa aacgattcga ggcaatcgag gtaaaaatca
      121 gaagcctgtt catattgtaa cggcttatga tgggggtcat catcttagtt tgggacaggt
      181 agcggttgag gagaaaagta atgaaattgt tgccattcct cagttattgc ggacaattga
      241 tatccgtaaa agcattgtaa cgatagacgc aatgggcacg cagacggcta tcgttgatac
      301 gattataaaa ggtaaagcag actattgctt agccgtcaaa ggaaatcaag aaacacttta
      361 tgatgatatt gctctttatt ttagtgatgt caacttattg gaagaactcc aagaaaatgc
      421 acagtattat cagactgttg aaaaatctag gggacagatt gaagttagag aatactgggt
      481 gtcttccgat atcaaatggt tgtgtcaaaa ccatcccaaa tggcataagt tacg
//
LOCUS       DATWEK010000136          493 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.136, whole genome shotgun sequence.
ACCESSION   DATWEK010000136 DATWEK010000000
VERSION     DATWEK010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.136"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..176)
                     /locus_tag="VCR92_001954"
     CDS             complement(<1..176)
                     /locus_tag="VCR92_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015968624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEP4268972.1"
                     /translation="MTEIMTFNGIGMSQYFRITDIIRPIGNKRTVSTDTSPFLGVNIQ
                     EIKIGAKEHKIKFD"
     gene            complement(173..>493)
                     /locus_tag="VCR92_001955"
     CDS             complement(173..>493)
                     /locus_tag="VCR92_001955"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP4268973.1"
                     /translation="ALGAMYDKVQAFSYRAEDLIGAGSTNFSHSIQVKSDLDKAIKAK
                     VEIVQEKSNEVMEKAIDAMGRLADRPIDMRLNDDTLIASTSDRYQDYQQTQITRTNRM
                     WGRP"
BASE COUNT          124 a           98 c           87 g          184 t
ORIGIN      
        1 atgtcaaatt tgattttgtg ttctttagct ccgattttaa tttcttggat attcaccccc
       61 aaaaaaggag aagtgtcagt tgacaccgtc cttttattac caatcgggcg aataatgtca
      121 gtaattctaa agtattgaga catcccaata ccgttaaaag tcattatttc tgtcatggtc
      181 taccccacat tctgttagta cgtgtaatct gtgtttgttg ataatcttga tatctatcgc
      241 tagtagatgc aataagcgtg tcgtcattca atcgcatatc gattggacgg tctgcgagtc
      301 tgcccattgc atctatagct ttttccatta cttcgtttga tttttcttgt acaatctcaa
      361 cttttgcttt gattgcttta tctaaatcgg atttaacctg gatactgtgt gagaaattag
      421 ttgatccagc tccgattagg tcttcagctc tgtagctaaa tgcttgtact ttgtcataca
      481 ttgcacctaa agc
//
LOCUS       DATWEK010000137          409 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.137, whole genome shotgun sequence.
ACCESSION   DATWEK010000137 DATWEK010000000
VERSION     DATWEK010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.137"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..374
                     /locus_tag="VCR92_001956"
     CDS             <1..374
                     /locus_tag="VCR92_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEP4268974.1"
                     /translation="FLPLAKYIETIDDDTDEETDDTGYYDGDGTPEETVTSVSGAYSV
                     SGLYDAEDKAQALIASKRYEIGDGRRVWHRVVESNGKKSFTQIANVSGIKAGSGDATA
                     YEEFECTLKWIKKPIEKAITE"
BASE COUNT          128 a           71 c           95 g          115 t
ORIGIN      
        1 cgttcttacc attggctaaa tacatcgaaa ctatcgatga cgacacagac gaagaaacag
       61 atgacactgg ttactatgac ggtgatggta caccagaaga aacggttaca tctgtttctg
      121 gtgcttactc tgtttctggt ctatatgatg cggaggataa ggcgcaagct ctaattgcat
      181 ctaaacgcta tgaaatcggt gatggtcgtc gtgtatggca tcgtgtagtt gagtcaaacg
      241 gcaagaagtc atttactcaa atcgctaacg tttctggcat taaagctggt tctggtgatg
      301 cgacagctta tgaagaattc gaatgcacac tcaaatggat taaaaagcca attgagaaag
      361 ctattacaga atagaaaggt ttgaaatatg tcacgagttt ataattttg
//
LOCUS       DATWEK010000138          405 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.138, whole genome shotgun sequence.
ACCESSION   DATWEK010000138 DATWEK010000000
VERSION     DATWEK010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.138"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..>405
                     /locus_tag="VCR92_001957"
     CDS             <1..>405
                     /locus_tag="VCR92_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="HEP4268975.1"
                     /translation="HYYLTTTGSCIDFGEEGAVGRGNKTHGIISSFRPNTMEAPAGKN
                     CTYFVGKVWGFLSDTIAKEIYEAFNTPCQIIMQLNIGSKLYRPTHLFIQTEESVDQER
                     VLEIVNRHLNNGKQNTNLILSTQHFIPKTNVY"
BASE COUNT          147 a           56 c           68 g          134 t
ORIGIN      
        1 accattatta tttaactact acaggttctt gtattgattt cggagaagaa ggtgcagttg
       61 gtcgaggtaa taaaactcat ggtatcatat caagttttag gccaaatact atggaagcac
      121 cagctggaaa aaattgtact tattttgtag gaaaggtttg gggatttttg tctgatacta
      181 ttgccaaaga aatttatgaa gcattcaata ctccctgtca aatcattatg caattaaata
      241 ttggatcaaa attgtataga ccaacccatt tatttattca gacagaagaa agtgttgatc
      301 aagaaagagt attagaaatt gttaacaggc atttaaataa tggtaaacaa aatactaatt
      361 taatcttgtc aactcaacat tttattccta aaaccaatgt ttatg
//
LOCUS       DATWEK010000139          350 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28788
            SAMN08562584-rid19743753.denovo.139, whole genome shotgun sequence.
ACCESSION   DATWEK010000139 DATWEK010000000
VERSION     DATWEK010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562584
            Sequence Read Archive: SRR6746879
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919223.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919223.2
            Genome Coverage       :: 204x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 07:38:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,958
            CDSs (total)                      :: 1,922
            Genes (coding)                    :: 1,873
            CDSs (with protein)               :: 1,873
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 28 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 10 of 49
            Pseudo Genes (multiple problems)  :: 12 of 49
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562584-rid19743753.denovo.139"
                     /strain="MGAS28788"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Oregon"
                     /collection_date="2012"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(150..>350)
                     /locus_tag="VCR92_001958"
     CDS             complement(150..>350)
                     /locus_tag="VCR92_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEP4268976.1"
                     /translation="VPYYEATLRTDYYVESKPNASSADKEFIKAGTRVRVYEKVNGWS
                     RINASQSDQWVEDKYLSNATQV"
BASE COUNT          119 a           69 c           52 g          110 t
ORIGIN      
        1 tttaataata agaaatcaca aaatatttta gcacaaaaaa gaaaaaaatc aacgaaaatg
       61 cttaaataac aattaaaatc tttataacaa aaacagcccc cgcaaaagcg agggcatttg
      121 tcttatctaa aggagcttta cctcctattt tatacttgtg ttgcattaga taaatactta
      181 tcttcgaccc actggtcaga ctgagaagcg ttaatacgtg accatccatt cactttttca
      241 tagactctta cacgagttcc tgccttgata aattctttat cagcgctact tgcgtttggc
      301 ttagactcta cataatagtc tgttctaagg gttgcttcgt agtaaggtac
//
